| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 2.702e-37 | -84.20 | ONDER_CDH1_TARGETS_2_DN | MSigDB lists | ONDER_CDH1_TARGETS_2_DN | 445 | 140 | 17758 | 1761 |
EXPH5,KLK10,IL15RA,LGR4,EPAS1,IL18,F11R,SDC1,NUP62CL,EPCAM,CYP1A1,AP1M2,ALDH1A3,DUSP10,CLDN4,TACSTD2,TINAGL1,PTPRE,CD55,CELSR2,ARHGDIB,RBM47,HPSE,KCNK1,PLK2,ZNF165,DDX58,PRSS8,PARP12,FAM169A,ITGA6,FXYD3,SOX9,ABCG2,CNTNAP2,SLC1A3,B4GALT4,HERC6,S100A2,ANO1,PRRG4,MECOM,CA2,LYPD3,FLRT3,RIMS3,KCNN4,BHLHE41,AIM1,MAP3K9,TMEM51,SORL1,MAST4,ALS2CL,RIMS2,IGSF3,FAM69A,KLK5,CORO2A,PIP4K2C,EPHA1,STEAP1,CDK5R1,FRMD4B,PTPRF,EPN3,FGD6,KLK7,SERPINB1,IFIH1,HOOK1,SEMA3A,XDH,PLA2G4A,GRHL2,ST14,RPS6KA1,CD82,MGST2,DDR1,TMPRSS4,EPS8L2,IER3,CDS1,SCNN1A,ARTN,CDH1,CYP4F11,CDH3,OAS3,EPB41L4B,TSPAN1,SNX10,GM2A,SEMA3B,MBP,CYB5R2,SLC39A8,RAB38,DUOX1,POPDC3,INPP4B,KLF5,NRG1,SLC27A3,ANXA3,ARHGEF3,ESRP1,SDC4,ARL4C,CYB561,SIRPA,HDAC9,RNF128,CTSC,CD9,TSPAN13,ERBB3,SYK,NFE2L3,HES1,ARAP2,GCLC,SYBU,LRRC1,FOS,CD83,GALNT3,TIMP3,SERPINA1,FGFR2,SPINT2,CLIP4,SPCS3,FZD5,TBC1D4,PTGES,L1CAM,OCLN,ARHGEF4 |
| 2.884e-32 | -72.62 | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | 530 | 147 | 17758 | 1761 |
BCAM,EPAS1,CRYM,ATP8A1,TMEM41B,PPFIBP2,NANS,SLC20A1,SDC1,BTG3,ANKS6,ARHGEF37,IQCE,ZFP36,ELF5,ALDH1A3,KLF3,RAB20,TACSTD2,PACSIN1,TLN2,SCARA3,TRAM1,CD55,SH3BGRL,EZR,PTGFRN,IDH1,LHFPL2,ARF4,MFAP3L,KLF12,WIPI1,FAM114A1,CAB39,EPB41L4A,TRAF5,GLCCI1,GAB1,HOXC13,ARAP3,NUAK1,FXYD3,NCKAP1,DHRS3,TNS3,GATA2,LYPD3,KCNN4,VASN,CADPS2,LIMCH1,NCEH1,ULBP2,SLC12A2,FAM69A,IGSF3,GFPT1,PRODH,SLC37A1,TBC1D8B,PIP4K2C,SPATA13,TP53INP2,PCTP,MUM1L1,FAS,FECH,EPN3,SH3BP4,FGD6,PLD1,PROM2,GALNT12,CAST,ATP2C2,ERBB2,IL13RA1,OSR2,FAM198B,DDR1,IER3,CDS1,FAM46A,BCL6,CDH3,PDE4D,EPB41L4B,RASGEF1A,TSPAN1,RAB27B,SCYL3,CPD,CLCN3,TIMP2,FZD4,SAT1,UTRN,SLC11A2,DOCK5,ALCAM,DAG1,NFIX,ARHGAP35,PTPRJ,CCDC149,SLC9A6,ZNF704,INPP4B,VSIG10,ABCA1,ANXA3,MACC1,PBX3,CYB561,FBXO6,NUCB2,BEX2,HOXB2,SH2D4A,PARM1,SGPL1,IRF2BPL,TMEM87B,MGAT4A,DRAM1,SLC44A2,TRIM62,ATP2B1,PVRL4,PDGFC,ARAP2,TACC1,RAPGEF2,LITAF,DIAPH2,LRRC1,PITX2,GALNT3,FUCA1,SWAP70,SYT7,RND3,TWSG1,ARRB1,GRIN2D,PKIA |
| 1.248e-29 | -66.55 | cytoplasm | cellular component | GO:0005737 | 10396 | 1255 | 17570 | 1756 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CARD10,GRM5,CDKN2C,MUC4,UBE2T,CRY2,TIAM1,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,COX6C,FAM21C,RABGGTA,ATG4A,MARCH8,FRY,PAIP2B,ATP5H,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,PANX2,DGKG,MYLIP,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,PLIN5,ETS2,CLMN,STK39,CFAP20,TMEM173,RUSC1,DOCK9,NQO1,INPP5D,PTTG1,C5orf30,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,SNX12,COX20,GABARAPL1,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,DCAF7,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,OPLAH,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,WDR45B,ACOT7,ILDR1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,ITPR2,MGAT5B,SPTB,FANCI,PLS3,CPNE2,BTG3,RPS6KA2,NPNT,PAPSS1,SLC44A1,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,KCNIP3,CELSR2,STAU2,NFE2L1,ARFRP1,SESN1,DZIP1L,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,HOXA9,ARRDC1,MYL12B,RRAGD,RUNX2,LMTK3,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,RGMB,MGAT4B,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,RASGRP2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,HOXB7,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,TTC21B,PDGFA,WDR44,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,IDE,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,CMAS,PINK1,CPEB4,HAL,CDCA8,ERI2,HMGN3,LBR,AIP,VPS26A,PARM1,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,GCNT1,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,PALD1,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,METAP2,SGCE,SPATA18,SLC35C1,KIF13A,POR,GDE1,BMP1,WBSCR27,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,AGBL5,FAM83D,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,CYP39A1,ZFYVE9,EPS8L2,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,SEMA3B,ATG4D,DOCK4,COG2,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ITPR3,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,IGFBP6,CENPI,EPS8,HERC5,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,GOLGA2P5,RNF128,FUT8,DRAM1,CD9,CITED2,FARP2,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,RAB15,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,SP6,GLA,NRGN,CAPN1,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,GAD1,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PDE5A,NUBP1,C3orf58,RANBP9,STEAP1,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,SNX30,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,PDIA5,COL18A1,PHLDA1,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,SEPHS1,CHP1,C3orf52,GLO1,CD40,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,ARHGEF11,CIT,TGFBR1,COL4A5,TRIB2,NTAN1,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,A4GALT,RRBP1,ARVCF,CLIP2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,IL18,SYTL4,BARD1,CA8,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SPEF2,NWD1,TNIP1,SH3BGRL,MTRF1L,ICMT,PPP1R14C,CYP4F3,COL12A1,ANKRD6,DNM1L,LIMK1,SERPINB6,MRPS28,ARF6,GAB1,ALDH6A1,NFKBIE,NUAK1,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,TP53INP2,SPTLC2,CYB5A,DCP2,DHX32,NCOA3,SCARB2,TIMM8A,ITPR1,AURKA,MDH1,MAL2,ARPC2,DRP2,NDE1,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,TMSB15A,GALNT12,RGS20,TESK2,NUF2,PRKACA,APC2,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,SSH3,CAMSAP3,FZD4,CYS1,SYNE2,PLEKHO1,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,PKN1,NUCB2,ARHGEF40,GSTP1,ETS1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,ADD3,CTSC,ANKS1B,ARSG,ALG13,CALD1,TMBIM6,ADAM15,ECI2,PLEKHF1,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,GALNT3,FHL1,HMGA1,CENPE,UNKL,MYL9,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,SDC1,PDGFB,CNTRL,SHC3,ELF5,DUSP10,TLN2,TRAM1,DDX59,S100A13,NEB,CCDC38,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,SPATA13,EIF2AK1,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ITGA7,ATP1B3,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,CYP26A1,ATP6V0B,N4BP3,PLCG2,SRR,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,EVA1A,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,ANXA9,LTA4H,AIFM3,NDST3,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,RUSC2,GNE,BLVRB,PSMD10,NKRF,CRABP2,DSE,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,PRDX4,FUCA1,SERPINA1,NAT1,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PLXNA1,CCNB1,FAM101B,CENPN,NCS1,CTGF,ELMO2,ZFP36,RGS3,STEAP2,AOX1,PACSIN1,RCAN3,LAMP2,KIFC2,SNTB2,CASP9,NBPF3,TNS1,AGO4,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,ZFAND5,AHRR,SLC25A4,PLK2,GNPTAB,NKD1,FAM110C,SARAF,DHTKD1,EIF4EBP2,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,ISYNA1,MECOM,ITGA3,SNX18,PIK3AP1,BDH1,SORL1,PIKFYVE,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,MMD,AMER1,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,PRKAG2,DCK,CSNK1G1,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,RNF182,SNN,AIFM2,MNS1,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,SP4,NIN,PRDM11,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,APOBEC3H,SPR,SIX4,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,PGM2L1,ETAA1,GPER1,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,EXPH5,EMX1,CASP3,CPT2,HEBP1,CAMKK1,CACNB4,DNER,DENND2D,SH3KBP1,ABCD4,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,EDNRA,CXXC4,MDK,NEIL1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,CA2,NCEH1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,AMDHD1,GLCE,GNAS,FECH,NUDT16,PLPP3,CDCA5,NFKBIA,RHOBTB2,PITPNA,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,FRYL,ZDHHC12,RPN2,GOT1,PDIA6,F2R,SCYL3,MAP3K3,GCA,OSTM1,ERBB2IP,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,ARMC7,TRMT2B,POMGNT1,SAC3D1,IL17RB,MLPH,ADORA1,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,GCLC,NR4A1,ASPM,OGDHL,MBNL3,KLHL2,HLA-B,HNRNPH2,PRCP,DHRS2,SOX8,SNPH |
| 2.242e-28 | -63.66 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 665 | 162 | 17758 | 1761 |
ILDR1,SLC35D2,LGR4,EPAS1,FAM199X,CRYM,DNAJC3,PPFIBP2,TGOLN2,NANS,OAT,BTG3,ANKS6,LRRC6,CTGF,ALDH1A3,SLC44A1,ELF5,STEAP2,KCNS3,NTN4,PTPRE,TRAM1,CYP1B1,PCGF5,CD55,ACVR1C,GALNT7,PTGFRN,IDH1,STK17B,POR,WIPI1,GDE1,ATP7B,FAM114A1,FAM110C,AGFG2,EIF4EBP2,SCOC,SLC25A27,ASAH1,B4GALT4,TNFRSF19,ATG4A,GNS,FRY,PIK3AP1,SNX18,BDH1,TPST1,LIMCH1,NCEH1,SLC12A2,SNX7,GFPT1,B3GNT7,HPS3,SLC37A1,CORO2A,ZNF320,PDE5A,PCTP,STEAP1,PLIN5,CYB5A,FRMD4B,GNAS,EPN3,SLCO4A1,PLEKHH2,UAP1,PELI2,FGD6,CLMN,PITPNA,NR4A2,STK39,PLD1,MAL2,SERPINB1,NIPA1,DOCK9,UGP2,FAM92A1,ST14,GALNT12,CAST,RPS6KA1,ATP2C2,CCDC68,IL13RA1,FTH1,AIFM2,EPS8L2,CDS1,NOV,ATP6V0B,SCNN1A,EPB41L4B,LRP11,TSPAN1,PDIA6,NR2C1,SCYL3,MYO5B,CPD,TMTC1,ERLEC1,SEPT6,SAT1,SLC11A2,ATP1B1,DUSP4,PTPRJ,POPDC3,SECTM1,EFNA5,ST3GAL1,PRR15,BIN1,NKX3-1,CPEB4,CD63,DAP,GNE,GDF15,FBXO6,HOXB2,LBR,SH2D4A,TMEM63A,ADD3,GNB5,RRBP1,UBE2J1,DRAM1,TMBIM6,ATP8B1,C2orf72,CITED2,TPCN1,S100A6,PGM1,PHF20L1,LONRF3,PPARA,SNTB1,KLHL2,GALNT3,FUCA1,TMC5,DBI,DTX4,PGRMC1,OTUB2,SH3BGRL2,ETAA1,FZD5,AHR,DCBLD1,GOLGB1 |
| 3.888e-26 | -58.51 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 436 | 120 | 17758 | 1761 |
CASP3,SPRED1,BCAM,TTC39B,EPAS1,TMEM41B,ATP8A1,ATP2C2,PPFIBP2,CCDC68,ERBB2,IL13RA1,FAM198B,SLC20A1,SDC1,KREMEN1,ZNF275,CDS1,APLP2,ZNF823,EFR3A,ARHGEF37,ZFP36,KLF3,ALDH1A3,REEP1,AOX1,ZDHHC23,CDH3,CLDN4,RAB20,TACSTD2,EPB41L4B,EGLN3,RAB27B,TSPAN1,LRP11,S100A13,TIMP2,CD55,FZD4,SH3BGRL,SAT1,UTRN,EZR,SLC11A2,GALNT7,PTGFRN,LHFPL2,ALCAM,DAG1,ARF4,MFAP3L,ENPP1,PTPRJ,WIPI1,PLK2,FAM114A1,FAM110C,ZNF704,CAB39,VSIG10,EPB41L4A,TRAF5,GLCCI1,ST3GAL1,GAB1,NXT2,ANXA3,ARL4C,ASAH1,PBX3,GDF15,NUCB2,PARM1,ZNF432,DOPEY2,TMEM87B,GATA2,KIF13B,BMP7,DRAM1,ATP8B1,SLC44A2,TSPAN13,LIMCH1,KLF9,NCEH1,ULBP2,SLC12A2,TRIM62,ATP2B1,IGSF3,PHF20L1,RHOA,B3GNT2,PQLC3,TACC1,CORO2A,PIP4K2C,LITAF,FUCA1,EPN3,GALNT3,TIMP3,SWAP70,ACADSB,TWSG1,DBI,SH3BP4,ZDHHC7,ARRB1,MAL2,FZD5,NDFIP1,CPEB2,AHR,KLF7,PROM2,EHD1 |
| 1.026e-25 | -57.54 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 458 | 123 | 17758 | 1761 |
PLA2G4A,TRIM2,NQO1,DDIT4L,TSC22D3,ATP2C2,PPFIBP2,LMCD1,C5orf30,LYNX1,BCL2L1,DNER,KBTBD11,ERP29,EMP2,DENND2D,ARHGEF16,CYP26A1,PLS3,EPCAM,PDGFA,RAB15,SCNN1A,CDH1,LMO4,ALDH1A3,ENPP5,BRI3,CDH3,CLDN4,TACSTD2,GLB1L2,ACSL4,MANF,TINAGL1,TMEM37,TSPAN1,DLG3,TIPARP,ETV4,SP5,SMAGP,CYP1B1,SEMA3B,SUSD3,MYO5B,LAMP2,MBP,SLC39A8,SERTAD4,CYS1,EZR,TFAP2C,ASB13,ARHGEF26,ATP1A1,KCNMB4,GPRC5B,KCNK1,ABHD12,SIPA1L1,FAM110C,TLE1,SP6,HS3ST3B1,ANXA9,WBSCR27,SLC25A30,ST3GAL1,PRR15,ANXA3,COL9A3,NKX3-1,ALDH6A1,IGFBP6,FXYD3,SOX9,COL4A5,HMGN3,B4GALT4,DHRS3,ANO1,SLC9A2,HLA-A,ELF3,HDAC9,M6PR,SNTA1,RALGPS2,RNF128,FAM189A1,LLGL2,KCNN4,LYPD6,BDH1,AIM1,TMEM51,SGK1,IGFBP2,TSPAN13,KLF9,CITED2,SLC12A2,TLE6,MDFI,PDGFC,PLSCR1,GCLC,CORO2A,AIF1L,CRISPLD2,GPLD1,ENDOD1,HLA-B,FGFR2,MFSD2A,NFKBIA,HOXB13,LRRK1,TMEM159,PTGES,PROM2,ADAMTS16 |
| 1.959e-25 | -56.89 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 837 | 182 | 17758 | 1761 |
UGT8,FAM199X,VANGL1,DNAJC3,RET,FHDC1,ARFGEF1,MPP5,FAM101B,BARD1,CA8,TRIM68,CMTM6,FANCI,EPDR1,PLS3,ZNF823,GRHL1,NPNT,IL6ST,PHTF1,CEP78,PASK,KCNS3,ATRNL1,TRPC1,HYLS1,MANF,RNF26,PTPRE,PCGF5,SMARCA2,CENPA,SERTAD4,USP18,PIF1,ANLN,STK17B,ADRBK2,PRIM1,KDM4D,MAN2A2,TMEM164,ZNF114,KCNMB4,ANKRD6,LRIG1,FAM110C,NOD2,ZNF165,NFKBIZ,RAP1GAP,GLCCI1,E2F8,PRKAA2,LRRFIP2,HJURP,UBASH3B,RAB23,KIF23,GPSM2,BMP2K,PRRG4,ATG4A,OTUD1,B3GALNT1,IGF1R,SPIN4,SLC16A6,LIMCH1,CADPS2,PIM1,NCEH1,ZMYM1,CKAP4,CHSY3,MFI2,KIF20A,PRSS23,BTNL9,ANO6,ZNF320,SPATA13,TCF7,NPHP3,NFIB,G2E3,GNAS,NCOA3,SEMA4D,TMEM30A,PRPS2,SH3BP4,FAM83D,NDE1,NIPA1,ARHGAP11A,DLGAP5,IL15,IQGAP1,GALNT12,C5orf30,KCTD12,NUF2,TMEM170B,SLC7A2,STIL,KBTBD11,MNS1,ZNF385B,SS18,KIF14,REEP1,PLK4,ZDHHC23,RTKN2,LGMN,LMAN1,SNX10,CDKN2D,CTH,SIRT1,TMEM200B,ENPP4,FZD4,SLC39A8,CDC20,ALCAM,SP4,FZD7,NIN,ALDH5A1,PDLIM3,ZNF704,OVOL1,HS3ST3B1,SLC25A30,PPP2R2D,ZNF701,NKX3-1,DEPDC1,CENPI,CIT,EPS8,ARL4C,NKRF,NUCB2,SIX4,DNAJB9,IL17RB,RASSF8,CTNNBIP1,KIF5B,LYPD6,FAM20B,FAIM,NPTXR,SGCB,MED22,HMMR,RAB3B,ASPM,MBNL3,CXorf57,PRICKLE1,BORA,FOS,CD83,ENDOD1,ACADSB,RAB11FIP2,AMMECR1,NMI,OTUB2,CLIP4,UACA,SPCS3,ITGAV,CENPE,CMPK2,ZBTB33,DIS3L |
| 3.025e-25 | -56.46 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 487 | 127 | 17758 | 1761 |
LMO7,UGP2,EPAS1,AASS,CAST,ATP8A1,TSC22D3,EPHA4,LMCD1,ERBB2,IL13RA1,FTH1,SYTL2,CDS1,SESN3,CYP1A1,CTGF,N4BP3,ALDH1A3,KLF3,DUSP10,CDH3,CLDN4,TACSTD2,NTN4,IFIT1,SLC39A10,EGLN3,RAB27B,CD55,SNTB2,COQ10B,SERTAD4,PTGER4,LOXL2,ATP1B1,DUSP4,LHFPL2,ALCAM,MYL12A,ATP10D,FZD7,OPTN,MAP2,PLK2,ZNF704,TLE1,CAB39,KLF5,PIK3C2B,NFKBIZ,TRAF5,ST3GAL1,GAB1,ABCA1,HOXC13,PRSS8,ANXA3,FBLIM1,BMF,PARP12,PINK1,CPEB4,MACC1,NUAK1,FRMD6,DNAJB2,ARL4C,OSGIN2,ABCG2,GDF15,DSE,CRABP2,B4GALT4,SH2D4A,MECOM,ELF3,DTX3L,TNS3,ITGB8,CALD1,MGAT4A,FRAS1,BMP7,UBE2J1,TFAP2A,DRAM1,LIMCH1,CITED2,LRIF1,ATP2B1,PARP9,EPB41L5,PVRL4,HES1,PHF20L1,ARAP2,PCDH1,HPS3,SALL4,TACC1,CORO2A,RAPGEF2,ANO6,PRICKLE1,DIAPH2,PDE5A,LRRC1,NPHP3,PCTP,CRISPLD2,FAT4,RND3,TMEM30A,MATN2,SH3BP4,PGM2L1,ZDHHC7,UACA,SH3BGRL2,ITGAV,MAP3K5,SERPINB1,L1CAM,CPEB2,AHR,ABCG1 |
| 3.461e-25 | -56.32 | cytoplasmic part | cellular component | GO:0044444 | 7817 | 986 | 17570 | 1756 |
ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,AK7,SLC25A13,DNAJC3,HEXB,RET,FBXO2,MMADHC,TGOLN2,IL18,ISOC2,LACTB2,SYTL4,CARD10,EPDR1,CALM2,CDKN2C,DAPK2,PQLC2,PSMD1,AP1M2,MUC4,CABP1,CYP2S1,ALDH1A3,FUT1,TUBG1,TINAGL1,PIK3CD,ACOX2,TIAM1,MGAT5,APOBEC3G,ERAP2,NWD1,SPEF2,CDA,MTRF1L,TFAP2C,PRKAR2B,ICMT,RNF19B,CYP4F3,ARF4,COL12A1,ABR,ENPP1,CARHSP1,PLCG1,MID1IP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,HDAC1,SERPINB6,MRPS28,TMOD2,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NFKBIE,ALDH6A1,GGA1,RAB23,SLC36A4,GPSM2,COX6C,FAM21C,LMNA,RABGGTA,ATG4A,MARCH8,GNS,FRY,ATP5H,FLRT3,FAM13B,NEK2,PCYOX1,CADPS2,MYDGF,NCAM1,NDUFA12,NUP85,C9orf72,PPP6R1,MCCC2,HPS3,PQLC3,KIF20A,ERO1A,ELK1,NPHP3,TP53INP2,PCTP,SPTLC2,PSMA4,GNA11,SFXN5,DCP2,PLIN5,CYB5A,DHX32,SCARB2,TIMM8A,ITPR1,AURKA,MDH1,MAL2,NDE1,ARPC2,CFAP20,TMEM173,RUSC1,XDH,EGLN1,DOCK9,ARHGAP11A,MTM1,CCDC109B,NQO1,PAPSS2,GALNT12,INPP5D,PTTG1,RGS20,NUF2,MGST2,MVB12B,PRKACA,APC2,APPBP2,CDS1,CCND1,RCN1,MUC16,SCNN1A,CDH1,DACT1,XYLT2,ACSL4,RASGEF1A,RAB27B,CDKN2D,SNX10,TMEM9,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,FZD4,SEPT6,SYNE2,SAT1,CYS1,DNAJB14,RAB38,SNX12,COX20,GABARAPL1,IRS2,ALDH3B1,PDLIM3,CDK19,WFS1,SLC9A6,INPP4B,PNPLA6,SLC25A30,ISOC1,MAPK12,TTC8,TNRC6C,CKAP2,SDC4,HABP4,PDIA3,CTSZ,PKN1,NUCB2,GSTP1,SLC25A43,PDIA4,SGPL1,NEO1,CTNNBIP1,ADD3,FUT2,CTSC,ARSG,CALD1,ALG13,MGAT4A,FAM20B,CST3,BAX,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,TPCN1,S100A6,CRTAP,PARP9,ACBD5,AMOTL2,OPLAH,LCA5,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,ELOVL3,MRS2,GRIN1,UBE2A,AK4,BLVRA,NEURL1B,CRISPLD2,GALNT3,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,CENPE,HMGA1,FHL1,CMPK2,WDR45B,ACOT7,MYL9,ILDR1,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,NDC80,NDRG2,DNAJB11,F11R,ITPR2,MGAT5B,HDAC6,PDGFB,SDC1,SPTB,RPS6KA2,NPNT,SHC3,CNTRL,PAPSS1,SLC44A1,PASK,TMEM143,ABCA2,DUSP10,SCARA3,TRAM1,NEB,S100A13,SMAGP,PLK1,CD55,KCNIP3,STAU2,NFE2L1,EZR,KLK6,ARFRP1,ANLN,PRKRA,IDH1,SESN1,CDK1,RHEB,OPTN,DZIP1L,DPYSL3,TRIM9,PLCH1,HS6ST1,AGPAT2,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,ARRDC1,PIK3C2B,PIEZO1,MYL12B,MAFF,RRAGD,PRKAA2,LMTK3,BMF,LGALS3,CHCHD7,DNAJB2,FXYD3,RASA2,HLA-F,ASAH1,ADCK5,RAB6A,NCKAP1,CNTNAP2,B4GALT4,DHRS3,B4GALNT1,RINL,GATA2,EXOC8,SELK,MDFIC,AHCY,FAR2,WNT3A,PLCB2,MPHOSPH9,ALDH3A2,CKAP4,C9orf9,CYP26B1,CHSY3,DPYSL5,MRPS33,TESK1,RGMB,PCBP3,MGAT4B,EMC2,STRADB,SCRIB,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,EPN3,COQ10A,H1F0,COL13A1,PHLPP2,MFSD2A,CSF1,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,ATP1B3,CCNB2,IFI6,RNF146,NIPA1,NF2,UPF3B,UGP2,P3H2,XYLT1,TP53,ERBB2,FAM198B,LPIN3,STIL,EMP2,BCAP31,CYP26A1,SYTL2,PDGFA,ATP6V0B,WDR44,PLCG2,N4BP3,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,MINPP1,LMAN1,EGLN3,GM2A,DVL2,SULF2,CTH,CPD,PPIF,SIRT1,TMTC1,CLCN3,ERLEC1,EVA1A,AKT1,COQ10B,S100A4,CCSAP,CDC20,ACO1,MYL12A,DAG1,ATP13A2,TAPBP,DNAJC10,ATP1A1,IDE,IRF7,ANXA9,SYT13,AIFM3,LTA4H,ST3GAL1,NDST3,ARFGEF3,MAN2B2,BIN1,COL9A3,CMAS,PINK1,PACSIN2,GOLIM4,CPEB4,MACC1,CD63,RUSC2,HAL,BLVRB,GNE,CDCA8,PSMD10,NKRF,CRABP2,DSE,LBR,AIP,PARM1,VPS26A,DNAJB9,FZD6,M6PR,ZDHHC21,CCDC92,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,SYK,TLE6,GCNT1,FAH,RHOA,PSMB4,NR3C1,IFITM3,GUSB,AMFR,PLAUR,LITAF,PRICKLE1,STMN3,MAML2,GGH,COL7A1,PELI3,FNDC3A,BCAR1,RNPEP,BBS2,TXNDC11,BORA,MAPK8IP1,PRDX4,FUCA1,SERPINA1,SCG2,NAT1,PGRMC1,SPCS3,NDFIP1,UBE2C,TBC1D4,PTGES,ARHGEF9,ARHGEF4,DIS3L,GOLGB1,SUN1,LAMP1,GAA,SLC35D2,TXN,HSPG2,TSC22D3,ATP8A1,TAP1,PSME1,NANS,CCNB1,VASH1,PJA2,OAT,CENPN,NCS1,SLC9A7,TYMP,CYP1A1,CTGF,STIM1,ELMO2,ZFP36,OSBPL3,RGS3,PALD1,STEAP2,KCNS3,PIK3CA,AOX1,IRF2,SNX16,TACSTD2,MARCH2,PACSIN1,METAP2,LAMP2,SGCE,SPATA18,SNTB2,CASP9,SLC35C1,AGO4,KIF13A,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,POR,SLC25A4,PLK2,GNPTAB,FAM110C,BMP1,DHTKD1,SARAF,F2RL1,TRAF5,FGD1,DDX58,MRPL44,SCOC,TBC1D1,TMEM55B,HLA-E,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,HERC6,PSIP1,MESDC2,MECOM,DOPEY2,ITGA3,SNX18,ZNRF2,PIK3AP1,VASN,RPL39,BDH1,TPST1,PRKG1,SORL1,CACNA1D,PIKFYVE,SYTL3,GPR161,TRAK2,FAM69A,GFPT1,FADS2,PMPCB,PRODH,B3GNT7,KLK5,MMD,ADCK3,LPGAT1,CALM1,AMER1,PIP4K2C,VEZT,NPC2,ATP8B3,ANTXR1,GLT8D2,RASA1,STX3,FAS,DGKH,AP1AR,PLEKHH2,PRKAG2,FAAH,PELI2,DCK,AGBL5,FGD6,KLK7,PLIN3,MAP3K5,HOOK1,IFIH1,NRBP1,EHD1,PLA2G4A,SLC2A4,CEP70,ARMCX3,NLRX1,TRIP10,THRA,RPS6KA1,IQGAP1,CCDC110,CAST,RALBP1,ATP2C2,FTH1,BCL2L1,SNN,AIFM2,CYP39A1,MNS1,ZFYVE9,ACAP2,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,PHKA2,LGMN,TSPAN1,SULT2B1,NAGA,GPX4,SEMA3B,ATG4D,MYO5B,DOCK4,SEC23A,COG2,CAPN6,CYB5R2,PANK1,LYRM1,KIF1C,PRKCQ,SLC11A2,PKMYT1,ITPR3,TRIQK,ATP10D,NIN,CEP162,JAK1,DDOST,PPP2R5A,NGFRAP1,STK26,SLC27A1,KLF5,MLKL,HS3ST3B1,SLC27A3,NR3C2,COBL,NUDT6,ARHGEF3,IGFBP6,ATP9A,CENPI,EPS8,HERC5,APOBEC3H,FBXO6,SPR,DNAH3,HLA-A,SLC25A36,GOLGA2P5,RNF128,PTEN,FUT8,DRAM1,SGK3,CD9,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,FARP2,PDGFC,RASGRF1,ARAP2,ZWINT,ARHGEF28,ALDH2,SHMT1,B3GNT2,ERMAP,MPP1,FURIN,C1GALT1C1,DIAPH2,YES1,FOS,ARSK,KIF11,CPTP,GPLD1,DCTN6,NUCB1,ACADSB,FGFR2,PGM2L1,ERAP1,GPER1,LRRK1,WDR62,FZD5,ARSB,SLC25A38,ESPL1,OCLN,MELK,ESYT2,RGMA,EXPH5,CASP3,CRYM,CPT2,CAMKK1,VARS2,CACNB4,DNER,SLC8B1,ERP29,TRIM68,SH3KBP1,ABCD4,CHPF,ZFYVE16,RAB15,GRHL1,METTL7A,SIVA1,IMPAD1,DPYSL2,CEP78,PHTF1,DLG1,AKR1B1,TRPC1,RAB20,RP2,MYH14,CTTN,TECR,MYRIP,BTBD3,RASGRP1,LAMP3,CYP1B1,NLRP4,ATL1,TRIM8,CENPA,ITCH,USP18,ARHGDIB,PTGFRN,MRPS36,TYSND1,STK17B,EDNRA,MAN2A2,CXXC4,GPRC5B,HPSE,KCNK1,MADD,CAB39,SP6,GLA,NRGN,RAP1GAP,CAPN1,PCSK5,STARD3NL,GRN,LASP1,FAM213B,PIFO,ARAP3,PPP1R2,SERPINE2,PEX6,ASB9,ABCG2,CALM3,TEC,PHLPP1,ADAMTSL4,B3GALNT1,CA2,COL6A1,SUCO,HLA-C,NCEH1,GAD1,CCDC88A,SNX7,KDELR1,ELK3,OXR1,GYLTL1B,PDE5A,NUBP1,C3orf58,RANBP9,STEAP1,AMDHD1,GLCE,FECH,GNAS,UAP1,PLPP3,TMEM30A,NFKBIA,CDCA5,SH3BP4,RHOBTB2,CTSA,SHROOM2,JAK3,APOL2,COL16A1,SNX30,PROM2,CCNE2,LZTFL1,DYNLRB1,SLC25A24,SORBS1,SPC25,IL15,PSME2,PDIA5,COL18A1,TDRKH,PHLDA1,ARHGEF16,SLC25A48,SS18,CYP4F11,ZDHHC12,KIF14,FRYL,REEP1,FABP6,GOT1,DIXDC1,RPN2,ECE1,F2R,PDIA6,SCYL3,CHP1,MAP3K3,OSTM1,C3orf52,GLO1,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,BFSP1,SECTM1,PEX2,TLE1,SPTBN5,CYP2U1,REEP4,ABCA1,GLIS3,ANXA3,FBLIM1,GCLM,SORT1,ENO2,ARHGEF11,CIT,POC1B,TGFBR1,COL4A5,TRMT2B,POMGNT1,TMEM63A,KIF5B,TOP2A,CARD8,ADORA1,ADRBK1,MLPH,LLGL2,A4GALT,GALNS,RRBP1,KIAA0319,IQGAP3,CLIP2,MYO5A,B3GALT6,SUN2,PGM1,SYPL1,RAB3B,CFAP46,GCLC,SYBU,RC3H2,OGDHL,NADK2,KLHL2,CTSL,ARHGAP24,HLA-B,SWAP70,RND3,DHRS2,PRCP,CTSV,RAP2C,DTX4,ARRB1,UACA,MCUR1,PLOD3,CEP41,AHR,ABCG1,SNPH |
| 1.938e-24 | -54.60 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4650 | 643 | 17775 | 1757 |
KLK10,AASS,AK7,DNAJC3,RET,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,LACTB2,BARD1,CARD10,ZNF275,GRM5,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,TINAGL1,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RIMS3,RANBP1,NEK2,MAP3K9,ALPK1,ZMYM1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,RCN1,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,MX1,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SYNE2,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,TTC8,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SLC25A43,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,FUT2,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,TMBIM6,WWP1,MAPK11,NKAPP1,ADAMTS2,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,CNTNAP1,PITX2,RAB11FIP2,ACVRL1,NR1D2,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,SPTB,PLS3,BTG3,RPS6KA2,SHC3,CNTRL,MKRN3,IL6ST,PAPSS1,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,ZNF462,PLK1,THRB,PCGF5,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,ZBTB7B,RHEB,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,WIPI1,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,DHRS3,IGF1R,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,TP53,ERBB2,LPIN3,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,ANXA9,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,PSMD10,HMGN3,NKRF,GDF15,LBR,PPP2R3A,SIRPA,FZD6,DNAJB9,M6PR,ZDHHC21,FOXP2,CDK16,UBE2J1,GTF2F2,TRIM21,SGK1,BUB1,ABCD1,ALDH7A1,FAIM,SYK,ATP2B1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,COL7A1,BCAR1,DGKE,PRDX4,SERPINA1,FAT4,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,HSPG2,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,ZFP36,OSBPL3,PRICKLE3,IQCE,RGS3,FOSB,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,GALNT7,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,TNFRSF19,S100A2,TSPAN7,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,RPL39,PPP4R1,AIM1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,DDB2,KCNJ12,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,RPS6KA1,CD274,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,MYO5B,CAPN6,FOXJ2,PRKCQ,PYGO1,PKMYT1,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,DNAH3,FGF19,EFNB1,SCML1,WWP2,E2F7,RNF128,GNB5,DRAM1,SGK3,ERBB3,SPRY2,TRIM62,NCOA2,TGIF1,RASGRF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,CSTF2,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,ZCCHC12,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,ITCH,USP18,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,RNF113A,PDIK1L,RANBP9,MUM1L1,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,RARG,CCNE2,SPC25,HDAC11,MORC4,COL18A1,MRAS,ARHGEF16,SS18,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,IL17RB,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,BMP7,MYO5A,PGM1,RAB3B,ASPM,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,ZMIZ1,GEM,AHR,L1CAM,RAB3IL1 |
| 1.938e-24 | -54.60 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4650 | 643 | 17775 | 1757 |
KLK10,AASS,AK7,DNAJC3,RET,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,LACTB2,BARD1,CARD10,ZNF275,GRM5,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,TINAGL1,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RIMS3,RANBP1,NEK2,MAP3K9,ALPK1,ZMYM1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,RCN1,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,MX1,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SYNE2,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,TTC8,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SLC25A43,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,FUT2,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,TMBIM6,WWP1,MAPK11,NKAPP1,ADAMTS2,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,CNTNAP1,PITX2,RAB11FIP2,ACVRL1,NR1D2,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,SPTB,PLS3,BTG3,RPS6KA2,SHC3,CNTRL,MKRN3,IL6ST,PAPSS1,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,ZNF462,PLK1,THRB,PCGF5,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,ZBTB7B,RHEB,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,WIPI1,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,DHRS3,IGF1R,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,TP53,ERBB2,LPIN3,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,ANXA9,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,PSMD10,HMGN3,NKRF,GDF15,LBR,PPP2R3A,SIRPA,FZD6,DNAJB9,M6PR,ZDHHC21,FOXP2,CDK16,UBE2J1,GTF2F2,TRIM21,SGK1,BUB1,ABCD1,ALDH7A1,FAIM,SYK,ATP2B1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,COL7A1,BCAR1,DGKE,PRDX4,SERPINA1,FAT4,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,HSPG2,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,ZFP36,OSBPL3,PRICKLE3,IQCE,RGS3,FOSB,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,GALNT7,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,TNFRSF19,S100A2,TSPAN7,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,RPL39,PPP4R1,AIM1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,DDB2,KCNJ12,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,RPS6KA1,CD274,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,MYO5B,CAPN6,FOXJ2,PRKCQ,PYGO1,PKMYT1,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,DNAH3,FGF19,EFNB1,SCML1,WWP2,E2F7,RNF128,GNB5,DRAM1,SGK3,ERBB3,SPRY2,TRIM62,NCOA2,TGIF1,RASGRF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,CSTF2,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,ZCCHC12,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,ITCH,USP18,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,RNF113A,PDIK1L,RANBP9,MUM1L1,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,RARG,CCNE2,SPC25,HDAC11,MORC4,COL18A1,MRAS,ARHGEF16,SS18,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,IL17RB,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,BMP7,MYO5A,PGM1,RAB3B,ASPM,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,ZMIZ1,GEM,AHR,L1CAM,RAB3IL1 |
| 2.099e-24 | -54.52 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4361 | 611 | 17775 | 1757 |
KLK10,AK7,DNAJC3,RET,FBXO2,MMADHC,DHX8,LACTB2,SYTL4,MORF4L2,BARD1,CARD10,ZNF275,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,F12,ICMT,PPP1R14C,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ATG4A,ELF3,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,AURKA,MDH1,GDF11,DRP2,FBXO27,NDE1,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,IL13RA1,NUF2,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,ST5,RNF220,CDH1,DACT1,ACSL4,ARL4D,DLG3,RASGEF1A,RAB27B,CDKN2D,ETV4,SNX10,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,DNAJB14,RAB38,SNX12,NFIX,IRS2,CDK19,SLC9A6,AXL,CORO1C,INPP4B,RGS14,MAPK12,CTSZ,ANO9,PKN1,SLC25A43,ARHGEF40,ETS1,BEX2,SRPX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,NKAPP1,MAPK11,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,UBE2A,CXorf57,AK4,SNTB1,PITX2,ACVRL1,NR1D2,PPM1H,CENPE,HMGA1,ITGAV,FHL1,TRIM2,EPAS1,FAM199X,CUL4B,EPHA4,NDC80,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PLS3,BTG3,RPS6KA2,SHC3,CNTRL,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,PLK1,THRB,PCGF5,CBX6,CR2,ARFRP1,KLK6,IDH1,SESN1,RHEB,KDM4D,TRIM9,TMEM164,PLEKHG6,KCNMB4,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,RASA2,DNAJB2,ADCK5,HES2,RAB6A,IGF1R,GATA2,SPIN4,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,FOXD2,RASGRP2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,UPF3B,NF2,FOXM1,TP53,ERBB2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,EGLN3,MINPP1,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,PSMD10,HMGN3,NKRF,GDF15,LBR,FZD6,PPP2R3A,DNAJB9,SIRPA,ZDHHC21,FOXP2,CDK16,UBE2J1,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,FAIM,SYK,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,BCAR1,DGKE,PRDX4,SERPINA1,PGRMC1,SH3BGRL2,PPP2R3C,UBE2C,ARHGEF9,PTGES,HIPK3,ZBTB33,ARHGEF4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,RGS3,IQCE,PRICKLE3,OSBPL3,ZFP36,FOSB,PIK3CA,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,SAV1,CCNF,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,TNFRSF19,S100A2,PSIP1,TSPAN7,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,RPL39,BHLHE41,PPP4R1,PRKG1,ADCK2,DAPK1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,PRODH,PMPCB,DDB2,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,DGKH,MMP15,PRKAG2,TMEM54,TCEAL4,PCDH19,CDK18,KLK7,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,RPS6KA1,BCL2L1,CD274,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,EPHB4,PDE4D,PHKA2,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,ITPR3,ASB13,FZD7,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,EFNB1,FGF19,SCML1,WWP2,E2F7,GNB5,RNF128,PTEN,SGK3,DRAM1,ERBB3,SPRY2,TRIM62,NCOA2,RASGRF1,TGIF1,ALDH2,ZWINT,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,ABCB1,CSTF2,FZD5,NCAPG2,ESPL1,MELK,CXorf56,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,ZCCHC12,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ITCH,RGAG1,ROR1,ADRBK2,STK17B,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,CPPED1,NR2C2,CD99,ARAP3,SERPINE2,PPP1R2,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,RNF113A,PDIK1L,RANBP9,MUM1L1,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,RARG,TOB1,CCNE2,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,TWIST1,SCYL3,CKS2,MAP3K3,SUSD3,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,FRMD6,COL4A5,TGFBR1,TRMT2B,TRIB2,HMGXB4,HDAC9,TOP2A,IL17RB,KIF5B,CARD8,ADRBK1,LLGL2,MYCL,PGM1,RAB3B,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,GEM,ZMIZ1,AHR,L1CAM,RAB3IL1 |
| 2.250e-24 | -54.45 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4290 | 603 | 17775 | 1757 |
KLK10,AK7,DNAJC3,RET,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,BARD1,CARD10,ZNF275,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SLC25A43,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,PITX2,ACVRL1,NR1D2,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PLS3,BTG3,RPS6KA2,CNTRL,SHC3,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,PLK1,THRB,PCGF5,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,IGF1R,GATA2,SPIN4,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,TP53,ERBB2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,PSMD10,HMGN3,NKRF,GDF15,LBR,PPP2R3A,SIRPA,FZD6,DNAJB9,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,ABCD1,ALDH7A1,BUB1,FAIM,SYK,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,BCAR1,DGKE,PRDX4,SERPINA1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,ZFP36,OSBPL3,PRICKLE3,IQCE,RGS3,FOSB,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,S100A2,TNFRSF19,PSIP1,TSPAN7,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,RPL39,PPP4R1,ADCK2,PRKG1,DAPK1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,PRODH,DDB2,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,RPS6KA1,CD274,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,CAPN6,FOXJ2,PRKCQ,PYGO1,PKMYT1,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,FGF19,EFNB1,HLA-A,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,SGK3,DRAM1,ERBB3,TRIM62,SPRY2,NCOA2,TGIF1,RASGRF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,DIAPH2,FBXO9,C1GALT1C1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,CSTF2,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,ZCCHC12,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,CENPA,TRIM8,ITCH,USP18,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,RNF113A,PDIK1L,RANBP9,MUM1L1,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,RARG,CCNE2,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,IL17RB,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,PGM1,RAB3B,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,GEM,ZMIZ1,AHR,L1CAM,RAB3IL1 |
| 4.539e-24 | -53.75 | GOZGIT_ESR1_TARGETS_DN | MSigDB lists | GOZGIT_ESR1_TARGETS_DN | 691 | 157 | 17758 | 1761 |
TRIM2,TSC22D3,EPHA4,RET,LMCD1,CACNB4,SIPA1L2,SESN3,CYP1A1,RPS6KA2,NPNT,ELF5,MITF,AOX1,POF1B,ATRNL1,DUSP10,SNX16,TACSTD2,RASGRP1,CYP1B1,PCGF5,CELSR2,SH3BGRL,USP18,PIAS3,PLCH1,ENPP1,WIPI1,MAP2,PLK2,FAM114A1,NFKBIZ,TANC2,HOXC13,PRSS8,CD99,RUNX2,FAM169A,NUAK1,ITGA6,SOX9,ASB9,SAMD9,HERC6,DHRS3,LMNA,B3GALNT1,IGF1R,SLC16A6,FLRT3,FRAS1,AIM1,RUNDC3B,FAR2,SLC12A2,GAD1,MAST4,CKAP4,ABCC1,EPB41L5,SLC37A1,PRSS23,MICB,SPATA13,PDK3,NPC2,IFIT3,NUDT16,PVRL2,LTBP2,SHROOM2,IFI6,KLF7,NCKAP5,ARMCX3,GRHL2,PAPSS2,NF2,ATP2C2,COL18A1,FTH1,OSR2,FAM198B,SLC7A2,TMPRSS4,SYTL2,SCNN1A,FAM46A,TRANK1,SP100,BCL6,VAT1,TWIST1,IFIT1,TMEM64,TSPAN1,RAB27B,EGLN3,MX1,TMTC1,TIMP2,SLC39A8,SAT1,UTRN,ATP1B1,ALCAM,GABARAPL1,SHROOM3,SECTM1,INPP4B,TLE1,IRF7,ST3GAL1,SLC25A30,CTHRC1,IGFBP6,TSPAN15,MACC1,FRMD6,ATP9A,SELL,GDF15,COL4A5,TRIB2,NUCB2,CRABP2,HDAC9,CD109,CXCL16,MLPH,ITGB8,SLC27A6,FUT8,SGK1,FAM102A,TSPAN13,KLF9,MYO5A,RBMS2,S100A6,LCA5,MBNL3,STMN3,AK4,BLVRA,LEPR,SERPINA1,FGFR2,RND3,NAT1,CDCA7L,PGM2L1,SH3BGRL2,CPEB2,AHR,PKIA |
| 2.615e-23 | -52.00 | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 1033 | 205 | 17758 | 1761 |
EMX1,SIGIRR,EPAS1,PPM1J,SLC25A13,RET,TAP1,FHDC1,CACNA2D2,NDRG2,F11R,TP53I11,MGAT5B,SDC1,CARD10,DAPK2,CPNE2,AP1M2,CTGF,NPNT,ZFP36,PAQR5,PAPL,KCNS3,SERINC2,DUSP10,RAB20,TACSTD2,NTN4,TMEM37,SCARA3,SP5,SMAGP,USP18,EZR,ROR1,PIF1,ANLN,ZBTB7B,LHFPL2,STK17B,CDK1,ARHGEF26,COL12A1,PGF,ENPP1,CARHSP1,AGPAT2,ATP7B,FAM110C,RAB11FIP1,LEMD1,UNC5B,ITPKA,F2RL1,MAFF,E2F8,GAB1,SCN5A,SERPINE2,HJURP,LGALS3,CDKN1C,BVES,SOX9,KIF23,SLC1A3,DHRS3,ANO1,PRRG4,MECOM,TNS3,PIK3AP1,CYR61,GATA2,PRKG1,TMEM51,MDFIC,C10orf54,GAD1,ALS2CL,SNX7,DPYSL5,PRODH,PRSS23,MYBL2,PDE5A,NFIB,FRMD4B,SOX13,GNAS,BCAR3,ONECUT1,SLC4A4,FAM64A,PVRL2,ITGA7,MFSD2A,NR4A2,CDK18,MAL2,ARHGAP11A,SLC2A4,CCDC109B,SPC25,GRHL2,S100A11,ST14,DDIT4L,ERBB2,COL18A1,PKP2,SLC7A2,OSR2,STIL,EMP2,CCND1,NOV,RNF220,CDH1,PLCG2,N4BP3,EGLN3,SULF2,MYO5B,PTPRU,SLC39A8,PTGER4,UTRN,PRKCQ,ERBB2IP,ATP1B1,DUSP4,ITPR3,DOCK5,MAP3K6,FZD7,CMTM7,NFIX,BFSP1,POPDC3,SHROOM3,TSPAN18,VSIG10,EFNA5,MLKL,HS3ST3B1,SYT13,MAPK12,GLIS3,NKX3-1,CDH22,CD63,TSPAN15,SDC4,RASSF7,NOTUM,FGF19,SIX4,SLC9A2,FZD6,TMEM63A,IL17RB,TOP2A,E2F7,CXCL16,LLGL2,BMP7,A4GALT,CD9,ATP8B1,PLEKHF1,BUB1,IGFBP2,TAGLN2,ERBB3,GCNT1,NFE2L3,RASGRF1,HES1,ADAMTS2,RAB3B,ASPM,MBNL3,LITAF,PPARA,AIF1L,GRTP1,SNTB1,CRISPLD2,CD83,GALNT3,SWAP70,FAT4,SMTNL2,PLOD2,FGFR2,TBX18,UACA,LRRK1,ICOSLG,FZD5,UBE2C,OCLN,TLL2 |
| 1.558e-22 | -50.21 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4587 | 628 | 17775 | 1757 |
KLK10,AASS,AK7,DNAJC3,RET,CACNA2D2,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,BARD1,CARD10,ZNF275,CDKN2C,DAPK2,WEE1,MUC4,ALDH1A3,KLF3,FUT1,PIK3CD,RNF26,TIAM1,APOBEC3G,NWD1,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,RNF19B,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,FRY,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SLC25A43,SRPX2,BEX2,PDIA4,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,PITX2,ACVRL1,NR1D2,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PLS3,BTG3,RPS6KA2,CNTRL,SHC3,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,PLK1,THRB,PCGF5,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,DAZAP1,IGF1R,GATA2,SPIN4,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,TP53,ERBB2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,MACC1,PSMD10,HMGN3,NKRF,GDF15,LBR,VPS26A,PPP2R3A,SIRPA,FZD6,DNAJB9,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,ABCD1,ALDH7A1,BUB1,FAIM,SYK,ATP2B1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,BCAR1,DGKE,PRDX4,SERPINA1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LGR4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,ZFP36,OSBPL3,PRICKLE3,IQCE,RGS3,FOSB,PIK3CA,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,RPL39,PPP4R1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,PRODH,DDB2,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,VEZT,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,RPS6KA1,CD274,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,CAPN6,FOXJ2,PRKCQ,PYGO1,PKMYT1,C15orf39,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,FGF19,EFNB1,HLA-A,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERBB3,TRIM62,SPRY2,NCOA2,TGIF1,RASGRF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,DIAPH2,FBXO9,C1GALT1C1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,CSTF2,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,ZCCHC12,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,CENPA,TRIM8,ITCH,USP18,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ZNF114,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,PEX6,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,RNF113A,PDIK1L,RANBP9,MUM1L1,GNAS,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,RARG,CCNE2,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,FRYL,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,IL17RB,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,TOX2,MYO5A,PGM1,RAB3B,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,GEM,ZMIZ1,AHR,L1CAM,RAB3IL1 |
| 1.569e-22 | -50.21 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 329 | 95 | 17758 | 1761 |
TRIP10,DNAJC3,CUL4B,TGOLN2,PLXNA1,OSR2,CYP1A1,SP100,RGS3,IL6ST,N4BP3,CDKN1B,IRF2,MANF,PIK3CD,ECE1,MYBL1,NR2C1,MAP3K3,PPIF,DOCK4,COL6A2,TNIP1,RIPK2,NFE2L1,LOXL2,ATP1B1,RNF19B,ABR,OPTN,IRS2,DNAJC10,JAK1,RBM47,GPRC5B,P4HA2,LRIG1,INPP4B,ABCA1,PARP12,SDC4,SOX9,EFHD2,CYB561,DSE,ARHGEF40,ETS1,NRP2,HLA-A,PDIA4,ZNF432,GATA2,BHLHE41,CALD1,AIM1,COL6A1,DRAM1,SGK1,TRIM21,CD70,RFX5,HLA-C,CLIP2,TRIM62,TPCN1,IGSF3,MDFI,NFE2L3,AMOTL2,HES1,MMD,PRSS23,PLAUR,RAPGEF2,MGAT4B,STEAP1,BSDC1,CD83,HLA-B,SLCO4A1,ETS2,RAB11FIP2,DHRS2,CSF1,NFKBIA,NMI,SLC2A6,NETO2,SH3BP4,ARRB1,GEM,FZD5,PTGES,KLF7,EHD1 |
| 8.429e-22 | -48.53 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 430 | 111 | 17758 | 1761 |
PLA2G4A,KLK10,FAM92A1,IL15,TRIP10,RALBP1,RGS20,MMADHC,PKP2,IL18,PHLDA1,FAM101B,SH3KBP1,PLS3,BTG3,SP100,OSBPL3,ALDH1A3,AKR1B1,CDH3,PIK3CD,GM2A,ERAP2,MBP,LOXL2,PPP1R14C,DOCK5,CASP4,ATP10D,MYL12A,IRS2,DUOX1,ATP1A1,PTK7,SLC9A6,AXL,CORO1C,BMP1,PRKCDBP,KLF5,F2RL1,BIN1,FBLIM1,ANXA3,ARAP3,SERPINE2,IGFBP6,TBC1D1,FRMD6,HLA-E,ITGA6,UBASH3B,PM20D2,SAMD9,SLC1A3,GPSM2,DSE,S100A2,ETS1,GSTP1,SRPX2,FZD6,SIRPA,CD109,ADD3,ITGA3,ITGB8,CTSC,CALD1,TOX2,AIM1,PPP4R1,FXYD5,CCDC82,SGK1,MDFIC,SPRY2,ALDH3A2,CCDC88A,SNX7,FAM69A,WBP5,PDGFC,ELK3,KLK5,PLSCR1,NR3C1,STAT4,PARP4,BTN3A2,RUNX3,YES1,IFIT3,ANTXR1,FAS,STK17A,ETS2,RND3,TWSG1,TMEM30A,NMI,FAM83D,CLIP4,MDH1,FHL1,ATP1B3,ARPC2,TMEM173,DCBLD1,CYBRD1,ESYT2 |
| 1.379e-21 | -48.03 | pleura | COSMIC cancer mutations | pleura | 5040 | 673 | 17775 | 1757 |
KLK10,AASS,AK7,DNAJC3,RET,CACNA2D2,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,BARD1,CARD10,ZNF275,CDKN2C,DAPK2,WEE1,AP1M2,MUC4,ALDH1A3,KLF3,FUT1,PIK3CD,RNF26,TIAM1,APOBEC3G,NWD1,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,RNF19B,ARF4,PIAS3,PLCG1,MID1IP1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,GGA1,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,FRY,RANBP1,NEK2,MAP3K9,CADPS2,ALPK1,MYLIP,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,DCP2,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,MUC16,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,SHROOM3,CDK19,CORO1C,SLC9A6,AXL,SIPA1L1,INPP4B,RGS14,MAPK12,TNRC6C,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SLC25A43,SRPX2,BEX2,PDIA4,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,ACBD5,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,PITX2,SYT7,ACVRL1,NR1D2,PPM1H,CENPE,ITGAV,HMGA1,FHL1,ILDR1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PLS3,BTG3,CPNE2,RPS6KA2,SHC3,CNTRL,MKRN3,IL6ST,ELF5,DUSP10,ANO4,SCARA3,TLN2,MYBL1,TRAM1,ZNF462,PLK1,THRB,PCGF5,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,MAP2,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,B4GALT4,DAZAP1,IGF1R,SPIN4,GATA2,KIF13B,PIM1,PLCB2,ALDH3A2,CHSY3,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,TP53,ERBB2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,CLCN3,AKT1,FIGNL1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,KLHL13,MACC1,PSMD10,NKRF,HMGN3,GDF15,LBR,PARM1,VPS26A,PPP2R3A,NRP2,SIRPA,FZD6,DNAJB9,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,BUB1,ABCD1,ALDH7A1,FAIM,SYK,ATP2B1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,BCAR1,DGKE,PRDX4,SERPINA1,FAT4,ZNF214,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LGR4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,SLC9A7,ZFP36,OSBPL3,PRICKLE3,IQCE,RGS3,FOSB,PIK3CA,SNX16,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,TANC2,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,RPL39,PPP4R1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,CACNA1D,PIKFYVE,RIMS2,SOCS5,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,VEZT,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,FAAH,SLC4A3,TCEAL4,PCDH19,KLK7,CDK18,CABIN1,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,SLC2A4,REPS2,ARMCX3,TRIP10,RPS6KA1,FTH1,CD274,BCL2L1,DDR1,TMPRSS4,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,TSPAN1,PHKA2,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,C15orf39,ASB13,ITPR3,SP4,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,CENPI,ARL4C,HERC5,FBXO6,FGF19,EFNB1,HLA-A,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERBB3,TRIM62,SPRY2,NCOA2,TGIF1,RASGRF1,ZWINT,ALDH2,LONRF3,MPP1,ZKSCAN2,FURIN,C1GALT1C1,DIAPH2,FBXO9,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,AMMECR1,CSTF2,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,SIPA1L2,RAB15,ZCCHC12,TSPAN6,ANKRD12,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ZNF114,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,PEX6,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,OXR1,RNF113A,PDIK1L,RANBP9,MUM1L1,XKRX,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,RARG,CCNE2,NCKAP5,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,CYP4F11,FRYL,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,TLE1,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,COL4A5,TRMT2B,TRIB2,SBF1,HMGXB4,HDAC9,IL17RB,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,TOX2,MYO5A,PGM1,RAB3B,SYBU,MBNL3,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,RND3,HNRNPH2,RAP2C,GRAMD1C,ZMIZ1,GEM,AHR,L1CAM,RAB3IL1,ABCG1 |
| 2.802e-21 | -47.32 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5361 | 706 | 17775 | 1757 |
ACACB,KLK10,AK7,SLC25A13,DNAJC3,RET,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,ISOC2,LACTB2,DPP8,BARD1,CARD10,ZNF275,EPDR1,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,ACOX2,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,ABR,ARF4,PIAS3,PLCG1,MID1IP1,ATP7B,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,SPTLC2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SSH3,COL6A2,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,SDC4,PDIA3,CTSZ,ANO9,PKN1,ETS1,SLC25A43,ARHGEF40,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,TPCN1,S100A6,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,PITX2,NR1D2,ACVRL1,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TMEM131,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,FANCI,PLS3,BTG3,RPS6KA2,SHC3,CNTRL,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,NEB,ZNF462,PLK1,THRB,PCGF5,MCTP1,CELSR2,CBX6,EZR,CR2,KLK6,ARFRP1,ANLN,IDH1,SESN1,RHEB,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,MAP2,HOXA9,KLF11,PIK3C2B,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,HJURP,ZCCHC24,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,IGF1R,SPIN4,GATA2,FRAS1,PIM1,PLCB2,ALDH3A2,CYP26B1,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,SEMA3A,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,XYLT1,TP53,ERBB2,SLC7A2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,ZMAT1,BIN1,COL9A3,PINK1,GOLIM4,KLHL13,PSMD10,NKRF,HMGN3,GDF15,DSE,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,SH2D4A,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,WBP5,DLGAP1,HMMR,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,TXNDC11,BCAR1,DGKE,PRDX4,SERPINA1,FAT4,NETO2,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,HSPG2,LGR4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,VASH1,SLC9A7,CYP1A1,ANKS6,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,FOSB,PIK3CA,SNX16,RCAN3,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,LDB2,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,CALB2,KIF23,SLC1A3,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,DOPEY2,RALGPS2,ITGA3,SNX18,BHLHE41,SLC16A6,RPL39,PPP4R1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,IGSF3,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,PLEKHH2,TMEM54,TCEAL4,FAM83D,PCDH19,KLK7,CDK18,PER3,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,NLRX1,RPS6KA1,THRA,BCL2L1,CD274,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,ATG4D,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,C15orf39,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,COBL,IER5L,ARHGEF3,HAPLN3,CENPI,ARL4C,HERC5,FBXO6,FGF19,EFNB1,TEAD3,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERBB3,CNPY3,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,TGIF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,LRRC1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,AMMECR1,CSTF2,CCDC69,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,SIPA1L2,RAB15,ZCCHC12,IMPAD1,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,CAPN1,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,AIM1L,HLA-C,ZRANB1,SLC12A2,ETV7,CCDC88A,SNX7,ELK3,OXR1,RNF113A,PDIK1L,RANBP9,MUM1L1,GNAS,XKRX,BCAR3,UAP1,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,APOL2,RARG,CCNE2,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,RPN2,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,DOCK5,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,FRMD6,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,KIF5B,IL17RB,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,MYCL,MYO5A,PGM1,RAB3B,ASPM,RC3H2,SYBU,MBNL3,OGDHL,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,ENDOD1,SWAP70,RND3,HNRNPH2,DHRS2,RAP2C,DTX4,GRAMD1C,ZMIZ1,PLOD3,GEM,AHR,L1CAM,RAB3IL1,CD33,SNPH |
| 2.802e-21 | -47.32 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5361 | 706 | 17775 | 1757 |
ACACB,KLK10,AK7,SLC25A13,DNAJC3,RET,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,ISOC2,LACTB2,DPP8,BARD1,CARD10,ZNF275,EPDR1,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,ACOX2,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,SH3BGRL,PRKAR2B,LOXL2,PPP1R14C,ICMT,ABR,ARF4,PIAS3,PLCG1,MID1IP1,ATP7B,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,SPTLC2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,TIMM8A,ITPR1,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,CD82,PTTG1,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SSH3,COL6A2,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,SLC9A6,AXL,INPP4B,RGS14,MAPK12,SDC4,PDIA3,CTSZ,ANO9,PKN1,ETS1,SLC25A43,ARHGEF40,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,ALG13,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,TPCN1,S100A6,ADAMTS2,BCL9,RAPGEF2,PIK3R1,NUB1,CXorf57,UBE2A,AK4,SNTB1,PITX2,NR1D2,ACVRL1,PPM1H,CENPE,ITGAV,HMGA1,FHL1,TMEM131,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,FANCI,PLS3,BTG3,RPS6KA2,SHC3,CNTRL,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,NEB,ZNF462,PLK1,THRB,PCGF5,MCTP1,CELSR2,CBX6,EZR,CR2,KLK6,ARFRP1,ANLN,IDH1,SESN1,RHEB,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,MAP2,HOXA9,KLF11,PIK3C2B,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,HJURP,ZCCHC24,RASA2,DNAJB2,ADCK5,RAB6A,HES2,CNTNAP2,IGF1R,SPIN4,GATA2,FRAS1,PIM1,PLCB2,ALDH3A2,CYP26B1,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,SEMA3A,CCNB2,RNF146,USP43,NF2,UPF3B,FOXM1,XYLT1,TP53,ERBB2,SLC7A2,STIL,BCAP31,RAD23A,WDR44,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,ZMAT1,BIN1,COL9A3,PINK1,GOLIM4,KLHL13,PSMD10,NKRF,HMGN3,GDF15,DSE,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,SH2D4A,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,WBP5,DLGAP1,HMMR,HES1,RHOA,FBLN5,MOSPD2,LITAF,MAML2,TXNDC11,BCAR1,DGKE,PRDX4,SERPINA1,FAT4,NETO2,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,HSPG2,LGR4,VANGL1,TSC22D3,PPFIBP2,CAMK1D,CCNB1,VASH1,SLC9A7,CYP1A1,ANKS6,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,FOSB,PIK3CA,SNX16,RCAN3,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,LDB2,CCNF,SAV1,SLC25A5,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,CALB2,KIF23,SLC1A3,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,DOPEY2,RALGPS2,ITGA3,SNX18,BHLHE41,SLC16A6,RPL39,PPP4R1,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,IGSF3,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,PLEKHH2,TMEM54,TCEAL4,FAM83D,PCDH19,KLK7,CDK18,PER3,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,NLRX1,RPS6KA1,THRA,BCL2L1,CD274,DDR1,ZFYVE9,APOBEC3B,NOV,ZNF75D,DOK4,CDKN1B,PDE4D,EPHB4,PHKA2,ATG4D,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,C15orf39,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,COBL,IER5L,ARHGEF3,HAPLN3,CENPI,ARL4C,HERC5,FBXO6,FGF19,EFNB1,TEAD3,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERBB3,CNPY3,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,TGIF1,ZWINT,ALDH2,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,LRRC1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,AMMECR1,CSTF2,CCDC69,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,JARID2,LTBP1,CASP3,CAMKK1,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,SIPA1L2,RAB15,ZCCHC12,IMPAD1,TSPAN6,POF1B,RAB20,RP2,CTTN,PTPRE,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,GLA,RAP1GAP,CAPN1,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,AIM1L,HLA-C,ZRANB1,SLC12A2,ETV7,CCDC88A,SNX7,ELK3,OXR1,RNF113A,PDIK1L,RANBP9,MUM1L1,GNAS,XKRX,BCAR3,UAP1,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,SHROOM2,JAK3,TOB1,APOL2,RARG,CCNE2,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,SS18,RPN2,TWIST1,SCYL3,CKS2,SUSD3,MAP3K3,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,DOCK5,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,BHLHB9,PPP2R2D,LIFR,ENO2,ARHGEF11,FRMD6,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,HDAC9,KIF5B,IL17RB,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,MYCL,MYO5A,PGM1,RAB3B,ASPM,RC3H2,SYBU,MBNL3,OGDHL,RUNX3,TCEAL8,FOXL1,KLHL2,ARHGAP24,ENDOD1,SWAP70,RND3,HNRNPH2,DHRS2,RAP2C,DTX4,GRAMD1C,ZMIZ1,PLOD3,GEM,AHR,L1CAM,RAB3IL1,CD33,SNPH |
| 8.842e-21 | -46.17 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3789 | 532 | 17775 | 1757 |
KLK10,AK7,DNAJC3,RET,MMADHC,FBXO2,DHX8,LACTB2,BARD1,CARD10,CDKN2C,DAPK2,WEE1,ALDH1A3,KLF3,FUT1,PIK3CD,RNF26,TIAM1,APOBEC3G,SMARCA2,FBXL16,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,PIAS3,PLCG1,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,HOXC13,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,RANBP1,NEK2,MAP3K9,ALPK1,DGKG,NUP85,STAT4,MYBL2,ELK1,TP53INP2,GNA11,STK17A,DHX32,PTPRF,NCOA3,ETS2,ITPR1,AURKA,MDH1,GDF11,FBXO27,SERPINB1,ADAMTS16,EGLN1,ARHGAP11A,MTM1,CD82,PTTG1,RGS20,TESK2,NUF2,GRK6,PRKACA,APC2,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,CDKN2D,ETV4,SNX10,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,RAB38,DNAJB14,SNX12,NFIX,IRS2,CDK19,CORO1C,AXL,INPP4B,RGS14,MAPK12,CTSZ,ANO9,PKN1,ETS1,ARHGEF40,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ITGB8,CALD1,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,ADAMTS2,TACC1,BCL9,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,AK4,SNTB1,PITX2,ACVRL1,NR1D2,NR4A3,PPM1H,CENPE,ITGAV,HMGA1,TRIM2,EPAS1,EPHA4,CUL4B,ARFGEF1,DNAJB11,TP53I11,ITPR2,HDAC6,PDGFB,BTG3,RPS6KA2,CNTRL,SHC3,IL6ST,ELF5,DUSP10,SCARA3,MYBL1,TRAM1,PLK1,THRB,PCGF5,CD55,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,KDM4D,TRIM9,PLEKHG6,KCNMB4,HOXA9,KLF11,PIK3C2B,MAFF,RRAGD,PRKAA2,BMF,RUNX2,RASA2,DNAJB2,ADCK5,RAB6A,HES2,IGF1R,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,TESK1,PCBP3,CORO2A,SPATA13,STRADB,EIF2AK1,SCRIB,PDK3,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,ZDHHC7,PLD1,CCNB2,RNF146,USP43,NF2,FOXM1,TP53,ERBB2,STIL,RAD23A,LMO4,PLCG2,PLK4,BCL6,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,ACO1,PTGER4,MYL12A,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,CMTM4,BIN1,PINK1,GOLIM4,PSMD10,HMGN3,GDF15,LBR,PPP2R3A,SIRPA,FZD6,DNAJB9,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,ALDH7A1,BUB1,FAIM,SYK,DLGAP1,HES1,RHOA,LITAF,PPARA,MAML2,BCAR1,DGKE,SERPINA1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ARHGEF4,TTC39B,VANGL1,PPFIBP2,CAMK1D,CCNB1,OSBPL3,IQCE,RGS3,ZFP36,FOSB,PIK3CA,SNX16,SMYD5,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,PIF1,CCNF,SAV1,TP53I3,AHRR,ANKRD10,HLF,PLK2,NKD1,LRIG1,SERPINI1,UNC5B,F2RL1,TRAF5,FGD1,DDX58,CDK17,FRMD4A,CDKN1C,DGKQ,KIF23,S100A2,TNFRSF19,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,SNX18,BHLHE41,PPP4R1,ADCK2,PRKG1,DAPK1,TNFRSF12A,CD70,PIKFYVE,RIMS2,SOCS5,PRODH,DDB2,KLK5,ADCK3,PIP4K2C,NFIB,RASA1,FAS,DGKH,MMP15,PRKAG2,TMEM54,KLK7,NR4A2,CDK18,MAP3K5,NRBP1,PLA2G4A,SPRED1,TRIP10,RPS6KA1,THRA,CD274,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,DOK4,CDKN1B,PDE4D,EPHB4,MED30,NR2C1,FOXJ2,PRKCQ,PYGO1,PKMYT1,ASB13,ITPR3,FZD7,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,NGFRAP1,SLC27A1,MLKL,CBX7,IER5L,ARHGEF3,ARL4C,HERC5,FBXO6,FGF19,SCML1,WWP2,E2F7,RNF128,GNB5,PTEN,SGK3,DRAM1,ERBB3,SPRY2,TRIM62,NCOA2,TGIF1,RASGRF1,ALDH2,ZWINT,LONRF3,FURIN,FBXO9,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,FZD5,NCAPG2,ESPL1,MELK,DEF6,JARID2,CASP3,LTBP1,CAMKK1,DENND2D,KREMEN1,ABCD4,ARHGEF10L,RAB15,LRRC6,RAB20,CTTN,PTPRE,RASGRP1,NLRP4,CENPA,TRIM8,ITCH,USP18,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,CAB39,RAP1GAP,NR2C2,ARAP3,SERPINE2,PPP1R2,ETV5,ASB9,ZRANB1,ETV7,SNX7,ELK3,PDIK1L,RANBP9,BCAR3,UAP1,NFKBIA,RHOBTB2,ALPK3,PITPNA,JAK3,RARG,TOB1,CCNE2,SPC25,HDAC11,MRAS,ARHGEF16,SS18,TWIST1,SCYL3,CKS2,MAP3K3,SUSD3,PTPRU,GLO1,ERBB2IP,DUSP4,CD40,KCTD2,FANCE,CASP4,MAP3K6,SOCS3,PPP2R2D,LIFR,ENO2,ARHGEF11,TGFBR1,TRIB2,HMGXB4,HDAC9,TOP2A,IL17RB,CARD8,ADRBK1,LLGL2,BMP7,MYCL,PGM1,RAB3B,ASPM,NR4A1,SYBU,RUNX3,FOXL1,ARHGAP24,KLHL2,SWAP70,RND3,RAP2C,SOX8,GEM,ZMIZ1,AHR,RAB3IL1 |
| 6.925e-20 | -44.12 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 410 | 104 | 17758 | 1761 |
GAA,LGR4,EPAS1,IQGAP1,MORC4,COL18A1,F11R,PHLDA1,LTBP3,RCN1,CCND1,EPCAM,APLP2,SCNN1A,OSBPL3,VAT1,CLDN4,BRI3,TACSTD2,ECE1,CTTN,LGMN,PTPRE,DVL2,CPD,ATL1,CD55,TRIM8,TIMP2,TNIP1,S100A4,LYRM1,NFE2L1,HTATIP2,LOXL2,C15orf39,KCTD2,DAG1,OPTN,TAPBP,ALDH3B1,ATP1A1,DDOST,JAK1,RBM47,ABHD12,ST3GAL1,ABCA1,CAPN1,GRN,TTC8,PARP12,ENO2,HLA-E,HLA-F,ABCG2,ARL4C,FAM134A,EFHD2,ASAH1,POMGNT1,NTAN1,S100A2,LGALS3BP,H1FX,GNS,TMEM87B,ADD3,ITGA3,CALD1,FRAS1,FUT8,TOX2,CST3,CD9,FXYD5,MDFIC,HLA-C,CITED2,ALDH3A2,CRTAP,TGIF1,MFI2,IFITM3,MGAT4B,LITAF,NPC2,SNTB1,CRISPLD2,HLA-B,SCG2,CSF1,NFKBIA,NLRC5,CCDC69,CLIP4,UACA,ARRB1,CTSA,PLD1,NDFIP1,TOB1,L1CAM,EHD1 |
| 3.424e-19 | -42.52 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 400 | 101 | 17758 | 1761 |
LAMP1,AVPI1,CCDC109B,PAPSS2,NQO1,SSH1,EPAS1,CAST,IQGAP1,XYLT1,CUL4B,HEXB,IL13RA1,NANS,ERP29,CMTM6,BCAP31,PLS3,CCND1,APLP2,CTGF,DOK4,OSBPL3,PAPSS1,VAT1,TWIST1,CTTN,ACSL4,LMAN1,SCARA3,S100A13,LAMP2,COL6A2,SEC61B,TIMP2,OSTM1,COQ10B,LOXL2,MCFD2,IDH1,ATP10D,CASP4,ARF4,GABARAPL1,DPYSL3,TAPBP,JAK1,WIPI1,AXL,BMP1,NRG1,GRN,MAN2B2,MRC2,PCOLCE,IGFBP6,SERPINE2,RAB23,ARL4C,NUCB2,NTAN1,SRPX2,LGALS3BP,GNS,PTEN,CYR61,CALD1,COL6A1,RRBP1,CST3,DRAM1,TPST1,FXYD5,TNFRSF12A,TAGLN2,S100A6,SNX7,GFPT1,PDGFC,ADAMTS2,ELK3,FBLN5,RHOA,PLAUR,UBE2A,C1GALT1C1,RNPEP,STEAP1,PRDX4,ENDOD1,NUCB1,SWAP70,UAP1,AMMECR1,PRPS2,PGRMC1,PITPNA,STK39,ITGAV,PTGES,EHD1 |
| 4.332e-19 | -42.28 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 985 | 187 | 17758 | 1761 |
KLK10,IL15RA,TMEM41B,TAP1,ARFGEF1,MPP5,PLXNA1,DNER,NCS1,TYMP,CTGF,SHC3,IL6ST,PAQR5,PHTF1,KLF3,PIK3CA,IRF2,NTN4,RP2,CTTN,ERAP2,XKR8,LAMP3,LAMP2,SPEF2,CITED4,SERTAD4,USP18,NFE2L1,ROR1,ICMT,OPTN,AHRR,ANKRD10,GPRC5B,MAP2,PLK2,P4HA2,LIMK1,CAB39,EIF4EBP2,SERPINI1,NXT2,DDX58,BMF,RUNX2,PARP12,NFKBIE,ZNF395,SERPINE2,LGALS3,NUAK1,HLA-E,HLA-F,SAMD9,SLC1A3,HERC6,SPIN4,FLRT3,VASN,COL6A1,HLA-C,NDUFA12,CCDC88A,CKAP4,FAM69A,PAQR7,SOCS5,RGMB,VEZT,TCF7,STEAP1,STX3,CYB5A,FAS,PTPRF,NCOA3,SCARB2,AP1AR,UAP1,SLC4A4,ETS2,CSF1,NFKBIA,CGREF1,MATN2,FGD6,YOD1,STK39,TMEM159,SEMA3A,IFIH1,COL16A1,APOL2,EGLN1,EHD1,PLA2G4A,SPRED1,LZTFL1,CCDC109B,ARMCX3,PSME2,CAST,RGS20,MRAS,APC2,APLP2,NOV,FAM46A,TRANK1,SP100,EFR3A,BRI3,RPN2,OAS3,TMEM64,LGMN,RAB27B,CTH,PPIF,MX1,RIPK2,OSTM1,S100A4,SAT1,C3orf52,ATP1B1,C15orf39,NIN,TAPBP,C19orf66,CORO1C,SECTM1,ZNF704,OVOL1,ADAMTS14,EFNA5,MLKL,NR3C2,FRMD6,POC1B,ARL4C,HERC5,EFHD2,PBX3,CYB561,GDF15,DSE,SRPX2,DNAJB9,SLC25A36,ZDHHC21,DTX3L,CTSC,FUT8,RRBP1,DRAM1,SLC44A2,SGK1,TRIM21,FAM102A,TPCN1,PARP9,ACBD5,PHF20L1,PLSCR1,EIF5A2,MYEOV,C1GALT1C1,PELI3,CD83,ENDOD1,GALNT3,HLA-B,BANK1,PLOD2,RND3,NMI,NETO2,ERAP1,GEM,FZD5,CPEB2,PKIA,JARID2,TMEM131 |
| 5.516e-19 | -42.04 | anatomical structure morphogenesis | biological process | GO:0009653 | 2356 | 367 | 16441 | 1675 |
GAA,ADD1,HSPG2,LGR4,SSH1,AK7,RET,NRG2,IL18,PSME1,PLXNA1,VASH1,FAM101B,CALM2,WEE1,TYMP,PSMD1,CTGF,STIM1,ALDH1A3,PIK3CA,TACSTD2,PACSIN1,RCAN3,TIPARP,TIAM1,DNAAF3,SPEF2,CASP9,TFAP2C,LOXL2,SAV1,ZFAND5,ARHGEF26,COL12A1,ABR,PGF,PLCG1,DNM1L,LIMK1,TRAF3IP1,NKD1,LRIG1,BMP1,HDAC1,TMOD2,UNC5B,E2F8,HOXC13,FGD1,SCN5A,CDKN1C,ITGA6,SOX9,RAB23,SLC1A3,MERTK,ELF3,MECOM,ITGA3,FRY,CYR61,FLRT3,MEGF8,BHLHE41,TNFRSF12A,MYDGF,CACNA1D,NCAM1,PIKFYVE,EPB41L5,SALL4,CALM1,EPHA1,NPHP3,ANTXR1,NFIB,PSMA4,RASA1,MMP15,NCOA3,ETS2,SEMA4D,MATN2,FAM83D,AURKA,NR4A2,GDF11,ARPC2,CFAP20,ADAMTS16,EGLN1,EHD1,MTM1,SPRED1,FOXO6,GRHL2,TCTN2,ST14,THRA,IQGAP1,CAST,RPS6KA1,C5orf30,PKP2,BCL2L1,PRKACA,DDR1,NOV,DACT1,CNNM4,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,SNX10,SEMA3B,COL6A2,FZD4,FOXJ2,SAT1,HTATIP2,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,CEP162,EPHA10,IRS2,JAK1,SHROOM3,AXL,SLC9A6,PNPLA6,KLF5,NRG1,COBL,TTC8,CTHRC1,NKX3-1,TNRC6C,SDC4,CTSZ,PLPPR4,SPR,ETS1,HOXB2,FGF19,EFNB1,SRPX2,SIX4,NEO1,SGPL1,SCML1,CTNNBIP1,E2F7,PTEN,FJX1,BAX,CD9,ADAM15,ATP8B1,ERBB3,CITED2,SPRY2,S100A6,FARP2,RASGRF1,TGIF1,PDGFC,B3GNT2,ARHGEF28,FMN1,RAPGEF2,GRIN1,C1GALT1C1,YES1,CRISPLD2,GPLD1,CNTNAP1,PITX2,FGFR2,ACVRL1,TBX18,NR4A3,RYK,ERAP1,GRIN2D,ITGAV,FHL1,FZD5,OSR1,RGMA,MYL9,CASP3,EMX1,UGT8,EPAS1,EPHA4,MPP5,SDC1,PDGFB,CACNB4,SPTB,RPS6KA2,LRRC6,SHC3,NPNT,DPYSL2,IMPAD1,ELF5,DLG1,TRPC1,NTN4,RP2,CTTN,MYH14,BTBD3,RASGRP1,SP5,CYP1B1,THRB,ATL1,CELSR2,NFE2L1,EZR,ARFRP1,PRKRA,DZIP1L,DPYSL3,EDNRA,HS6ST1,HPSE,MAP2,HOXA9,MYL12B,CAPN1,PCSK5,RUNX2,SERPINE2,BVES,RASA2,CALM3,NCKAP1,DHRS3,CA2,IGF1R,GATA2,FRAS1,COL6A1,WNT3A,SLC12A2,ETV7,MDFI,CYP26B1,DPYSL5,ELK3,RGMB,STRADB,SCRIB,RANBP9,CDK5R1,SOX13,FOXD2,BCAR3,GNAS,ONECUT1,PVRL2,COL13A1,ITGA7,CSF1,PLPP3,EGFL7,PITPNA,JAK3,SHROOM2,SEMA3A,RARG,KLF7,HOXB7,NF2,FOXM1,PSME2,TP53,COL18A1,ERBB2,OSR2,STIL,IER3,TTC21B,PDGFA,SS18,SETDB2,ARTN,KIF14,LMO4,FRYL,BCL6,TWIST1,ECE1,NOTCH3,F2R,DVL2,FRS3,SIRT1,S100A4,DUSP4,MYL12A,DAG1,SOCS3,ARHGAP35,PTPRJ,PTK7,PTBP3,TLE1,SPTBN5,EFNA5,LIFR,COL9A3,PACSIN2,ARHGEF11,ADGRG1,POC1B,FRMD6,LRP4,PSMD10,AES,COL4A5,TGFBR1,CRABP2,PPP2R3A,NRP2,FZD6,KIF5B,CD109,BMP7,TFAP2A,SGK1,SYK,MYO5A,GCNT1,HES1,RHOA,PSMB4,CFAP46,NR4A1,PPARA,PRICKLE1,COL7A1,BBS2,FOXL1,ARHGAP24,FAT4,SCG2,TWSG1,PRCP,CTSV,SPINT2,PGRMC1,HOXB13,PLOD3,CEP41,ZMIZ1,SOX8,L1CAM |
| 7.973e-19 | -41.67 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | 423 | 104 | 17758 | 1761 |
EXPH5,SIGIRR,GRHL2,ST14,TSC22D3,ATP2C2,PPFIBP2,ERBB2,F11R,ERP29,DDR1,EMP2,FAM46C,DENND2D,CDS1,EPCAM,AP1M2,CDH1,GRHL1,METTL7A,IQCE,ENPP5,FUT1,SERINC2,CNNM4,CDH3,CLDN4,MYH14,RAB27B,TSPAN1,DLG3,SULT2B1,SCYL3,MYO5B,CAMSAP3,SSH3,KIFC2,USP18,ZBTB7B,PLCH1,PPP2R5A,RBM47,WFS1,OVOL1,ZNF165,FAM195A,ARRDC1,ANXA9,C1orf43,EPB41L4A,PRR15,PRSS8,LMTK3,ALDH6A1,MACC1,ESRP1,FXYD3,BLVRB,CYB561,CRABP2,SEPP1,ANO1,PRRG4,ELF3,AIM1L,MLPH,LYPD3,LLGL2,MGAT4A,FAM63A,SLC44A2,SORL1,TMBIM6,FAM102A,IGFBP2,CADPS2,TSPAN13,CACNA1D,ERBB3,MYLIP,MCCC2,EPB41L5,PVRL4,PRODH,PLEKHA6,PCDH1,SLC37A1,PIP4K2C,EPHA1,SPTLC2,CYB5A,SOX13,EPN3,TJP3,SYT7,FAAH,SPINT2,PPM1H,MAL2,HOOK1,TOB1,RUSC1,PROM2,ABCG1 |
| 8.034e-19 | -41.67 | regulation of signaling | biological process | GO:0023051 | 2886 | 430 | 16441 | 1675 |
TXN,LGR4,RET,CACNA2D2,NRG2,PSME1,IL18,SYTL4,PJA2,SLC20A1,CARD10,GRM5,CALM2,DAPK2,SESN3,PSMD1,CTGF,RGS3,IL31RA,KCNS3,CRY2,RCAN3,TIAM1,METAP2,TNIP1,ACVR1C,SH3BGRL,PBK,SLC35C1,PRKAR2B,ICMT,SLC25A5,POR,ARHGEF26,ABR,ANKRD10,ENPP1,PLCG1,SLC25A4,DNM1L,ANKRD6,PLK2,TRAF3IP1,NKD1,FAM110C,NOD2,HDAC1,EIF4EBP2,TMOD2,ITPKA,ARF6,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,FGD1,CDKN1C,NUAK1,ITGA6,SOX9,RAB23,SLC1A3,TNFRSF19,KIAA1161,LMNA,MECOM,TFAP4,ITGA3,RALGPS2,CYR61,PIK3AP1,RIMS3,VASN,FAM13B,DAPK1,MAP3K9,SORL1,TNFRSF12A,MYDGF,CACNA1D,NCAM1,RIMS2,GPR161,SOCS5,KLK5,CALM1,AMER1,NPHP3,PSMA4,PLIN5,STX3,RASA1,FAS,AP1AR,NCOA3,SEMA4D,PELI2,ITPR1,FAM83D,FGD6,NR4A2,GDF11,MAP3K5,RUSC1,XDH,ARHGAP11A,SPRED1,NLRX1,TRIP10,THRA,INPP5D,DDIT4L,RALBP1,IQGAP1,RGS20,GRK6,BCL2L1,MVB12B,PRKACA,APC2,ZFYVE9,EPS8L2,CCND1,NOV,APLP2,ST5,RNF220,SP100,DACT1,DAB2IP,PDE4D,RASGEF1A,LGMN,CDKN2D,MYT1,NR2C1,RIPK2,FZD4,PRKCQ,ITPR3,FZD7,IRS2,JAK1,WFS1,SLC9A6,AXL,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,NRG1,RGS14,CTHRC1,ARHGEF3,NKX3-1,IGFBP6,EPS8,PDIA3,PKN1,GSTP1,ARHGEF40,FGF19,NEO1,CTNNBIP1,GNB5,CTSC,PTEN,BAX,PLEKHF1,TMBIM6,SLC44A2,IGFBP2,MAPK11,ERBB3,CITED2,TRIM62,SPRY2,NCOA2,FARP2,RASGRF1,TGIF1,ARAP2,ARHGEF28,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,FURIN,FBXO9,GPLD1,CNTNAP1,FGFR2,ACVRL1,SYT7,DBI,TBX18,RYK,GRIN2D,ITGAV,GPER1,LRRK1,FZD5,SIGIRR,LTBP1,ILDR1,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,PDGFB,SLC8B1,ERP29,KREMEN1,TRIM68,SPTB,SH3KBP1,ARHGEF10L,SIPA1L2,NPNT,SHC3,ARHGEF37,IL6ST,SIVA1,TSPAN6,PASK,DLG1,AKR1B1,DUSP10,CTTN,SLC39A10,PTPRE,MYRIP,S100A13,RASGRP1,CYP1B1,CD55,TRIM8,ITCH,USP18,EZR,KLK6,ARHGDIB,PRKRA,SESN1,CDK1,RHEB,OPTN,CXXC4,PLEKHG6,ARHGEF19,KCNMB4,GPRC5B,AGPAT2,HPSE,MADD,RAB11FIP1,PRKCDBP,ADIPOR1,RAP1GAP,RRAGD,PRKAA2,LASP1,RUNX2,BMF,ARAP3,PPP1R2,LGALS3,SERPINE2,BVES,RASA2,UBASH3B,PDCL,CALM3,PHLPP1,DHRS3,FBLN1,IL18R1,ANO1,CA2,IGF1R,GATA2,KCNN4,MDFIC,C10orf54,WNT3A,ZRANB1,ALS2CL,MDFI,CYP26B1,SPATA13,STRADB,PDE5A,SCRIB,C3orf58,RANBP9,G2E3,CDK5R1,GNAS,MAPKAPK2,ONECUT1,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,RHOBTB2,EGFL7,JAK3,TOB1,IFI6,AFAP1,RNF146,LMO7,SORBS1,AVPI1,NF2,FOXM1,IL15,PSME2,TP53,ERBB2,EMP2,BCAP31,ARHGEF16,CYP26A1,IER3,TTC21B,PDGFA,KIF14,BCL6,CDH3,TWIST1,DIXDC1,ECE1,F2R,DVL2,FRS3,CTH,CHP1,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,AKT1,FIGNL1,S100A4,CDC20,ERBB2IP,DUSP4,CD40,MAP3K6,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,SECTM1,TLE1,EFNA5,IRF7,SPTBN5,ABCA1,ARFGEF3,GCLM,PINK1,CD63,ADGRG1,TSPAN15,ARHGEF11,LRP4,PSMD10,TGFBR1,AES,GDF15,HMGN3,NOTUM,CRABP2,TRIB2,AIP,HMGXB4,PPP2R3A,FZD6,CD109,KIF5B,CARD8,ADORA1,ADRBK1,LLGL2,CDK16,BMP7,BUB1,FAIM,IQGAP3,SYK,MYO5A,HES1,RHOA,RAB3B,PSMB4,ASPM,PLAUR,GCLC,RC3H2,SYBU,LITAF,PRICKLE1,STMN3,PELI3,FOXL1,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,PRCP,NETO2,UACA,ARRB1,SPCS3,NDFIP1,L1CAM,ARHGEF9,HIPK3,ARHGEF4 |
| 1.156e-18 | -41.30 | regulation of signal transduction | biological process | GO:0009966 | 2548 | 389 | 16441 | 1675 |
TXN,LGR4,RET,NRG2,PSME1,IL18,PJA2,SLC20A1,CARD10,GRM5,CALM2,DAPK2,SESN3,PSMD1,CTGF,RGS3,IL31RA,CRY2,RCAN3,TIAM1,METAP2,TNIP1,SH3BGRL,PBK,SLC35C1,ICMT,SLC25A5,POR,ARHGEF26,ABR,ANKRD10,ENPP1,PLCG1,DNM1L,ANKRD6,PLK2,TRAF3IP1,NKD1,FAM110C,NOD2,HDAC1,TMOD2,ARF6,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,FGD1,CDKN1C,NUAK1,ITGA6,SOX9,RAB23,TNFRSF19,KIAA1161,LMNA,MECOM,TFAP4,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,FAM13B,DAPK1,MAP3K9,SORL1,TNFRSF12A,MYDGF,NCAM1,GPR161,SOCS5,KLK5,CALM1,AMER1,NPHP3,PSMA4,PLIN5,RASA1,FAS,NCOA3,SEMA4D,PELI2,ITPR1,FAM83D,FGD6,NR4A2,GDF11,MAP3K5,RUSC1,XDH,ARHGAP11A,SPRED1,NLRX1,TRIP10,THRA,INPP5D,DDIT4L,RALBP1,RGS20,GRK6,BCL2L1,MVB12B,PRKACA,APC2,ZFYVE9,EPS8L2,CCND1,NOV,APLP2,ST5,RNF220,SP100,DACT1,DAB2IP,PDE4D,RASGEF1A,LGMN,CDKN2D,NR2C1,RIPK2,FZD4,PRKCQ,FZD7,IRS2,JAK1,WFS1,AXL,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TRABD2A,NRG1,RGS14,CTHRC1,ARHGEF3,NKX3-1,IGFBP6,EPS8,PDIA3,PKN1,GSTP1,ARHGEF40,FGF19,NEO1,CTNNBIP1,GNB5,CTSC,PTEN,BAX,PLEKHF1,TMBIM6,SLC44A2,IGFBP2,MAPK11,ERBB3,CITED2,TRIM62,SPRY2,NCOA2,FARP2,RASGRF1,TGIF1,ARAP2,ARHGEF28,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,FURIN,FBXO9,CNTNAP1,FGFR2,ACVRL1,TBX18,RYK,GRIN2D,ITGAV,GPER1,LRRK1,FZD5,SIGIRR,LTBP1,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,ERP29,KREMEN1,TRIM68,SPTB,SH3KBP1,ARHGEF10L,SIPA1L2,NPNT,SHC3,ARHGEF37,IL6ST,TSPAN6,SIVA1,DLG1,AKR1B1,DUSP10,CTTN,SLC39A10,PTPRE,S100A13,RASGRP1,CYP1B1,CD55,TRIM8,ITCH,USP18,EZR,ARHGDIB,KLK6,PRKRA,SESN1,CDK1,RHEB,OPTN,CXXC4,PLEKHG6,ARHGEF19,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,RAP1GAP,RRAGD,PRKAA2,LASP1,RUNX2,BMF,ARAP3,PPP1R2,LGALS3,SERPINE2,RASA2,UBASH3B,PDCL,CALM3,PHLPP1,DHRS3,FBLN1,IL18R1,IGF1R,GATA2,KCNN4,MDFIC,C10orf54,WNT3A,ZRANB1,ALS2CL,MDFI,CYP26B1,SPATA13,STRADB,PDE5A,C3orf58,RANBP9,G2E3,CDK5R1,GNAS,MAPKAPK2,ONECUT1,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,RHOBTB2,EGFL7,JAK3,TOB1,IFI6,AFAP1,RNF146,SORBS1,AVPI1,NF2,FOXM1,IL15,PSME2,TP53,ERBB2,EMP2,BCAP31,ARHGEF16,CYP26A1,IER3,TTC21B,PDGFA,KIF14,BCL6,CDH3,TWIST1,DIXDC1,F2R,DVL2,FRS3,CTH,CHP1,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,AKT1,FIGNL1,S100A4,ERBB2IP,DUSP4,CD40,MAP3K6,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,SECTM1,TLE1,IRF7,SPTBN5,ABCA1,ARFGEF3,GCLM,PINK1,ADGRG1,CD63,ARHGEF11,TSPAN15,LRP4,PSMD10,TGFBR1,AES,GDF15,NOTUM,CRABP2,TRIB2,AIP,PPP2R3A,FZD6,HMGXB4,CD109,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,BUB1,FAIM,IQGAP3,SYK,MYO5A,HES1,RHOA,PSMB4,ASPM,PLAUR,GCLC,RC3H2,LITAF,PRICKLE1,STMN3,PELI3,FOXL1,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,PRCP,NETO2,UACA,ARRB1,NDFIP1,L1CAM,ARHGEF9,HIPK3,ARHGEF4 |
| 1.868e-18 | -40.82 | positive regulation of biological process | biological process | GO:0048518 | 5310 | 702 | 16441 | 1675 |
ACACB,DNAJC3,HEXB,RET,CACNA2D2,NRG2,IL18,MORF4L2,SYTL4,BARD1,CARD10,LTBP3,GRM5,CALM2,DAPK2,PSMD1,ALDH1A3,SEMA3G,PIK3CD,TIAM1,TIPARP,SMARCA2,TNIP1,SH3BGRL,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,ABR,PIAS3,PGF,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,NOD2,AGFG2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,E2F8,GAB1,HOXC13,SCN5A,GGA1,ITGA6,SOX9,MERTK,LMNA,ELF3,TFAP4,MEGF8,FLRT3,FAM13B,RANBP1,NEK2,MAP3K9,MYDGF,NCAM1,MYLIP,NUP85,SALL4,STAT4,PYM1,MYBL2,ELK1,TP53INP2,PSMA4,PLIN5,STK17A,NCOA3,ETS2,SEMA4D,SETD3,ITPR1,AURKA,STK39,GDF11,ARPC2,CFAP20,TMEM173,RUSC1,XDH,DOCK9,ARHGAP11A,GRHL2,NQO1,INPP5D,RGS20,PKP2,MGST2,MVB12B,PRKACA,APC2,TNFSF9,CCND1,ST5,RNF220,CDH1,SP100,SH3BP1,DACT1,RTKN2,ACSL4,RAB27B,RASGEF1A,MYT1,ETV4,ENPP4,RIPK2,FZD4,SYNE2,CDCA2,NUSAP1,GTF2A2,NFIX,IRS2,CDK19,WFS1,CORO1C,AXL,SIPA1L1,PLEKHG1,RGS14,MAPK12,CTHRC1,TCAF1,TNRC6C,NKX3-1,CKAP2,SDC4,BTN3A1,PDIA3,PKN1,ETS1,GSTP1,ARHGEF40,SRPX2,NEO1,CTNNBIP1,CXCL16,ITGB8,CTSC,FAM20B,CST3,BAX,PLEKHF1,IGFBP2,MAPK11,S100A6,PLSCR1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,CNTNAP1,PITX2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,HMGA1,CENPE,FHL1,OSR1,USF2,ILDR1,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,LMCD1,DNAJB11,F11R,NENF,ITPR2,HDAC6,PDGFB,SDC1,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,MITF,ELF5,PASK,SCARA3,MYBL1,S100A13,SMAGP,ZNF462,PLK1,THRB,PCGF5,CD55,CITED4,NFE2L1,CR2,EZR,KLK6,PRKRA,CDK1,RHEB,OPTN,DPYSL3,KDM4D,PLEKHG6,KLF12,AGPAT2,PRKCDBP,KLF11,PIEZO1,MAFF,RRAGD,PRKAA2,PRSS8,RUNX2,BMF,LGALS3,DNAJB2,RASA2,NCKAP1,FBLN1,IL18R1,ANO1,TNS3,DAZAP1,IGF1R,RINL,GATA2,TBCD,MDFIC,PIM1,WNT3A,PLCB2,RGMB,SPATA13,STRADB,SCRIB,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,CSF1,NLRC5,ATP1B3,SEMA3A,RNF146,AVPI1,NF2,HOXB7,UPF3B,FOXM1,TP53,ERBB2,LPIN3,STIL,EMP2,BCAP31,SYTL2,IER3,RAD23A,PDGFA,LMO4,PLCG2,BCL6,PLK4,CDH3,ESPN,NOTCH3,TMEM64,LMAN1,EGLN3,GM2A,DVL2,SULF2,CTH,SIRT1,PPIF,CLCN3,TIMP2,AKT1,S100A4,CDC20,SERTAD3,PTGER4,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,RBL1,MMP17,PTK7,EFNA5,IRF7,ARFGEF3,BIN1,PINK1,MACC1,ADGRG1,CD63,DAP,SELL,PSMD10,GDF15,HMGN3,CRABP2,PARM1,NRP2,PPP2R3A,GTF2F2,TFAP2A,SGK1,TRIM21,BUB1,SYK,TLE6,NFE2L3,HES1,RHOA,PSMB4,NR3C1,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,BCAR1,BBS2,MAPK8IP1,CD83,BANK1,TWSG1,SCG2,CDCA7L,NMI,PPP2R3C,ICOSLG,NDFIP1,TBC1D4,UBE2C,ARHGEF9,ARHGEF4,LAMP1,TXN,LGR4,ATP8A1,PSME1,CAMK1D,CCNB1,SLC20A1,NCS1,CYP1A1,CTGF,STIM1,ELMO2,ZFP36,RGS3,IL31RA,FOSB,SERINC2,PIK3CA,IRF2,TACSTD2,PACSIN1,ACVR1C,CASP9,NBPF3,SAV1,LDB2,SLC25A5,POR,ARHGEF26,AHRR,PLK2,NKD1,BMP1,FAM110C,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,CDKN1C,SCOC,THEMIS2,TBC1D1,HLA-E,SLC25A27,KIF23,SLC1A3,TNFRSF19,PSIP1,KIAA1161,MECOM,C9orf69,ITGA3,RALGPS2,CYR61,SNX18,PIK3AP1,DAPK1,SORL1,TNFRSF12A,CACNA1D,GPR161,RIMS2,SOCS5,EPB41L5,KLK5,MMD,MFI2,TBC1D8B,MICB,CALM1,AMER1,ANO6,PIP4K2C,EPHA1,NFIB,RASA1,STX3,FAS,MMP15,PRKAG2,PELI2,FAM83D,FGD6,KLK7,NR4A2,MAP3K5,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,ARMCX3,THRA,RPS6KA1,IQGAP1,RALBP1,CD274,BCL2L1,AIFM2,MNS1,EPS8L2,NOV,ACAP2,CDKN1B,DAB2IP,PDE4D,IFIT1,LGMN,TSPAN1,MED30,NR2C1,SEMA3B,DOCK4,FOXJ2,UTRN,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,FZD7,PPP2R5A,JAK1,STK26,NGFRAP1,TRIOBP,SLC27A1,NRG1,KLF5,COBL,DENND5B,WASF3,ARHGEF3,PCOLCE,DEPDC1,EPS8,PBX3,EFNB1,FGF19,TEAD3,HLA-A,ADGRB2,SIX4,WWP2,E2F7,RNF128,PTEN,SGK3,SLC44A2,ERBB3,CITED2,CNOT6L,CNPY3,TRIM62,SPRY2,OSGIN1,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARHGEF28,ARAP2,FURIN,YES1,GRTP1,FOS,GPLD1,FGFR2,TBX18,RYK,ERAP1,GRIN2D,LRRK1,GPER1,FZD5,ARSB,ESPL1,MELK,RGMA,JARID2,EXPH5,CASP3,CAMKK1,CACNB4,ERP29,DENND2D,EPCAM,ARHGEF10L,RAB15,SIPA1L2,HSF2,GRHL1,ARHGEF37,TSPAN6,DPYSL2,SIVA1,DLG1,AKR1B1,TRPC1,RP2,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,NLRP4,TRIM8,ITCH,ARHGDIB,STK17B,EDNRA,MDK,ARHGEF19,GPRC5B,HPSE,MADD,CAB39,SP6,ADIPOR1,NRGN,RAP1GAP,CAPN1,NR2C2,GRN,LASP1,PIFO,ARAP3,SERPINE2,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,CA2,KCNN4,SUCO,C10orf54,ZRANB1,ALS2CL,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,GNAS,BCAR3,ONECUT1,NUDT16,PLPP3,TMEM30A,CDCA5,NFKBIA,SH3BP4,CTSA,EGFL7,JAK3,TOB1,RARG,COL16A1,PROM2,KLF7,SORBS1,IL15,PSME2,COL18A1,IL27RA,OSR2,PHLDA1,ARHGEF16,SS18,ARTN,KIF14,TWIST1,DIXDC1,ECE1,EPB41L4B,F2R,FRS3,CHP1,MAP3K3,ERBB2IP,DUSP4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,JADE1,BHLHB9,SECTM1,OVOL1,TLE1,SPTBN5,LIFR,ABCA1,GLIS3,GCLM,ANXA3,ARHGEF11,TSPAN15,CIT,LRP4,TGFBR1,AES,TRIB2,SBF1,HDAC9,IRF2BPL,KIF5B,TOP2A,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,TOX2,IQGAP3,SUN2,RAB3B,NR4A1,GCLC,ASPM,RC3H2,RGCC,RUNX3,ARHGAP24,CTSL,HLA-B,SWAP70,RAP2C,DTX4,ARRB1,ZMIZ1,SOX8,L1CAM,AHR,RAB3IL1,ABCG1 |
| 2.677e-18 | -40.46 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 436 | 105 | 17758 | 1761 |
SORBS1,DLGAP5,EPAS1,IL15,AASS,KCTD12,IL13RA1,OAT,NUP62CL,IER3,APLP2,CYP1A1,RPS6KA2,CDH1,ALDH1A3,BCL6,TMEM143,TUBG1,IFIT1,PIK3CD,TLN2,MYBL1,GM2A,CTH,LAMP3,CYP1B1,ING1,COL6A2,S100A4,SAT1,PTGER4,TFAP2C,PRKAR2B,ATP1B1,CCNF,ALCAM,POR,ATP13A2,PGF,HPSE,ANKRD6,NGFRAP1,PLK2,EIF4EBP2,SERPINI1,NRGN,LIFR,GRN,BIN1,SORT1,CDKN1C,SERPINE2,ITGA6,SDC4,HABP4,CNTNAP2,GPSM2,DSE,SEPP1,DNAH3,BMP2K,TOP2A,GNS,RNF128,ALPP,RRBP1,SGK3,RUNDC3B,CD9,TSPAN13,NCAM1,ULBP2,CLIP2,WBP5,CYP26B1,HES1,ALDH2,NR4A1,OGDHL,CXorf57,FOS,SPTLC2,MAPK8IP1,CRISPLD2,GLCE,RASGRP2,FUCA1,TIMP3,SWAP70,ACADSB,H1F0,DHRS2,NAT1,ITGA7,CGREF1,ABCB1,FGD6,NR4A2,CDK18,FHL1,FZD5,L1CAM,IFI6,AHR,ACOT7 |
| 3.610e-18 | -40.16 | system development | biological process | GO:0048731 | 4011 | 557 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,NRG2,IL18,GRM5,CALM2,CDKN2C,WEE1,PSMD1,ALDH1A3,CLDN4,PIK3CD,SEMA3G,TIPARP,TIAM1,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,LIMK1,ATP7B,TRAF3IP1,HDAC1,TMOD2,ITPKA,ARF6,E2F8,GAB1,HOXC13,SCN5A,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FRY,FLRT3,MEGF8,MYDGF,NCAM1,DGKG,MYLIP,REC8,SALL4,NPHP3,PSMA4,GNA11,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,CLMN,AURKA,GDF11,ARPC2,DRP2,NDE1,XDH,ADAMTS16,EGLN1,PAPSS2,GRHL2,PKP2,PRKACA,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,AXL,CORO1C,WFS1,SIPA1L1,PNPLA6,RGS14,MAPK12,CTHRC1,TNRC6C,NKX3-1,SDC4,CTSZ,PKN1,PLPPR4,GSTP1,ETS1,HOXB2,SRPX2,NEO1,SGPL1,CTNNBIP1,ITGB8,IGSF9,CST3,BAX,ADAM15,TMBIM6,WWP1,SGCB,S100A6,ADAMTS2,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,AK4,CRISPLD2,PITX2,CNTNAP1,ACVRL1,DBI,NR4A3,ITGAV,FHL1,OSR1,USF2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,SDC1,PDGFB,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,CELSR2,NFE2L1,EZR,CR2,KLK6,PRKRA,ANLN,IDH1,CDK1,RHEB,DPYSL3,HS6ST1,MAP2,HOXA9,MYL12B,MAFF,RUNX2,LGALS3,RASA2,CNTNAP2,NCKAP1,DHRS3,IL18R1,TNS3,DAZAP1,IGF1R,GATA2,KIF13B,FRAS1,WNT3A,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,PRX,CDK5R1,MAPKAPK2,COL13A1,ITGA7,PHLPP2,CSF1,PRPS2,CCNB2,SEMA3A,HOXB7,NF2,FOXM1,TP53,ERBB2,STIL,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,MBP,TIMP2,AKT1,S100A4,CDC20,PTGER4,MYL12A,DAG1,PTPRJ,PTK7,EFNA5,LTA4H,BIN1,COL9A3,CDH22,ADGRG1,PSMD10,CRABP2,FZD6,NRP2,PPP2R3A,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,SYK,TLE6,GCNT1,HES1,RHOA,PSMB4,PPARA,PRICKLE1,STMN3,FNDC3A,BBS2,PRDX4,FAT4,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,LGR4,SSH1,HSPG2,TMEM41B,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,TACSTD2,ZBTB18,PACSIN1,SGCE,CASP9,CCNF,LDB2,SAV1,ZFAND5,HLF,PLK2,LRIG1,NKD1,BMP1,DHTKD1,SERPINI1,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,CDKN1C,SLC25A27,SLC1A3,HERC6,TNFRSF19,KIAA1161,MECOM,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,RIMS2,IGSF3,EPB41L5,MMD,AMER1,CALM1,ANO6,EPHA1,NFIB,RASA1,STX3,FAS,MATN2,FAM83D,PCDH19,NR4A2,EHD1,FOXO6,SPRED1,ST14,RPS6KA1,CAST,IQGAP1,THRA,BCL2L1,DDR1,NOV,APLP2,DOK4,CDKN1B,CNNM4,DAB2IP,PDE4D,EPHB4,SEMA3B,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,EPHA10,JAK1,NRG1,KLF5,CBX7,COBL,WASF3,HAPLN3,CENPI,PBX3,SPR,SEPP1,FGF19,EFNB1,SIX4,TEAD3,ADGRB2,E2F7,PTEN,FJX1,CD9,ATP8B1,ERBB3,CITED2,SPRY2,FARP2,RASGRF1,PDGFC,TGIF1,ARHGEF28,B3GNT2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,SLC25A38,MELK,JARID2,RGMA,EXPH5,CASP3,EMX1,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,MYH14,CTTN,BTBD3,RASGRP1,SP5,CYP1B1,ATL1,EDNRA,MDK,HPSE,GPRC5B,NRGN,CAPN1,PCSK5,NR2C2,GRN,SERPINE2,BVES,ETV5,CALM3,CA2,COL6A1,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,BCAR3,GNAS,FECH,ONECUT1,PLPP3,TMEM30A,ALPK3,EGFL7,PITPNA,SHROOM2,JAK3,RARG,KLF7,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,PHLDA1,SETDB2,ARTN,KIF14,FRYL,TWIST1,DIXDC1,ECE1,FRS3,MAP3K3,PTPRU,OSTM1,GLO1,IGSF8,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,OVOL1,TLE1,PTBP3,SPTBN5,LIFR,ANXA3,ARHGEF11,CIT,LRP4,AES,TGFBR1,COL4A5,HDAC9,KIF5B,TOP2A,MDM1,ADORA1,ADRBK1,LLGL2,MYCL,BMP7,TOX2,KIAA0319,MYO5A,ASPM,NR4A1,RC3H2,TTC7A,RUNX3,FOXL1,ARHGAP24,SWAP70,DHRS2,PRCP,SPINT2,CTSV,ARRB1,HOXB13,ZMIZ1,SOX8,PLOD3,L1CAM,AHR |
| 4.372e-18 | -39.97 | regulation of response to stimulus | biological process | GO:0048583 | 3566 | 506 | 16441 | 1675 |
LAMP1,TXN,LGR4,DNAJC3,RET,TAP1,NRG2,PSME1,IL18,PLXNA1,CAMK1D,VASH1,PJA2,SLC20A1,CARD10,GRM5,CALM2,DAPK2,SESN3,PSMD1,AP1M2,CTGF,ELMO2,RGS3,IL31RA,PIK3CA,CRY2,SEMA3G,PIK3CD,RCAN3,TIAM1,APOBEC3G,METAP2,TNIP1,SH3BGRL,PBK,CASP9,SLC35C1,AGO4,F12,ICMT,SLC25A5,POR,ARHGEF26,ABR,ANKRD10,ENPP1,PLCG1,DNM1L,ANKRD6,PLK2,LIMK1,TRAF3IP1,NKD1,FAM110C,NOD2,HDAC1,TMOD2,ARF6,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,LZTS1,FGD1,DDX58,SEMA6B,SCN5A,CDKN1C,SCOC,NUAK1,THEMIS2,ITGA6,HLA-E,SOX9,RAB23,SLC1A3,TNFRSF19,KIAA1161,LMNA,MECOM,TFAP4,ITGA3,RALGPS2,CYR61,PIK3AP1,MEGF8,VASN,FAM13B,DAPK1,MAP3K9,PRKG1,SORL1,TNFRSF12A,ALPK1,MYDGF,PIKFYVE,NCAM1,NUP85,GPR161,SOCS5,KLK5,MICB,CALM1,AMER1,ANO6,PIP4K2C,ELK1,NPHP3,PSMA4,PLIN5,STX3,RASA1,FAS,PTPRF,NCOA3,SEMA4D,PELI2,ITPR1,FAM83D,FGD6,MDH1,NR4A2,STK39,KLK7,GDF11,ARPC2,MAP3K5,CFAP20,PER3,IFIH1,NUP58,TMEM173,RUSC1,XDH,ARHGAP11A,SPRED1,NLRX1,TRIP10,THRA,INPP5D,RPS6KA1,DDIT4L,RALBP1,RGS20,GRK6,BCL2L1,MVB12B,PRKACA,APC2,ZFYVE9,EPS8L2,CCND1,NOV,APLP2,ST5,RNF220,CDH1,SP100,FAM46A,DACT1,CDKN1B,DAB2IP,PDE4D,IFIT1,RASGEF1A,LGMN,CDKN2D,MYT1,NR2C1,SEMA3B,ENPP4,RIPK2,FZD4,PRKCQ,ATP1B1,ITPR3,FZD7,IRS2,JAK1,CDK19,STK26,WFS1,SLC9A6,AXL,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,NRG1,RGS14,CTHRC1,ARHGEF3,TNRC6C,NKX3-1,IGFBP6,EPS8,BTN3A1,PDIA3,HERC5,PKN1,ETS1,GSTP1,ARHGEF40,FGF19,HLA-A,NEO1,CTNNBIP1,GNB5,CTSC,PTEN,BAX,PLEKHF1,TMBIM6,SLC44A2,IGFBP2,MAPK11,ERBB3,CITED2,CNPY3,SPRY2,TRIM62,NCOA2,PARP9,FARP2,RASGRF1,TGIF1,ARAP2,ARHGEF28,PLSCR1,BCL9,MPP1,RAPGEF2,PIK3R1,GRIN1,FURIN,FBXO9,YES1,FOS,GPLD1,CNTNAP1,FGFR2,ACVRL1,NR1D2,TBX18,RYK,NR4A3,ERAP1,GRIN2D,ITGAV,GPER1,HMGA1,LRRK1,FZD5,SIGIRR,LTBP1,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,KREMEN1,TRIM68,SPTB,SH3KBP1,HTR1D,ARHGEF10L,SIPA1L2,RPS6KA2,NPNT,SHC3,ARHGEF37,IL6ST,SIVA1,TSPAN6,DLG1,AKR1B1,DUSP10,CTTN,SLC39A10,SCARA3,PTPRE,S100A13,RASGRP1,SMAGP,CYP1B1,CD55,TRIM8,ITCH,USP18,CR2,EZR,KLK6,ARHGDIB,PRKRA,SESN1,CDK1,RHEB,OPTN,KDM4D,MDK,CXXC4,PLEKHG6,ARHGEF19,GPRC5B,HPSE,AGPAT2,MADD,PRKCDBP,ADIPOR1,RAP1GAP,RRAGD,PRKAA2,LASP1,RUNX2,ARAP3,BMF,PPP1R2,SERPINE2,LGALS3,HLA-F,RASA2,UBASH3B,PDCL,CALM3,NCKAP1,TEC,PHLPP1,DHRS3,FBLN1,IL18R1,ANO1,IGF1R,GATA2,KCNN4,MDFIC,C10orf54,HLA-C,WNT3A,ZRANB1,ALS2CL,MDFI,CYP26B1,SPATA13,STRADB,PDE5A,EIF2AK1,C3orf58,RANBP9,G2E3,CDK5R1,GNAS,FECH,MAPKAPK2,NUDT16,ONECUT1,PVRL2,PLPP3,PHLPP2,CSF1,NFKBIA,SH3BP4,NLRC5,RHOBTB2,EGFL7,YOD1,JAK3,SEMA3A,TOB1,AFAP1,IFI6,RNF146,SORBS1,AVPI1,NF2,FOXM1,IL15,PSME2,TP53,ERBB2,IL27RA,SLC7A2,EMP2,BCAP31,ARHGEF16,CYP26A1,IER3,TTC21B,PDGFA,ARTN,KIF14,PLCG2,BCL6,CDH3,TWIST1,DIXDC1,F2R,DVL2,FRS3,CTH,CHP1,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,ERLEC1,AKT1,FIGNL1,S100A4,PTGER4,ERBB2IP,DUSP4,CD40,CASP4,MAP3K6,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,SECTM1,TLE1,EFNA5,SPTBN5,IRF7,ABCA1,ARFGEF3,GCLM,PINK1,CD63,ADGRG1,TSPAN15,ARHGEF11,LRP4,PSMD10,SELL,TGFBR1,AES,GDF15,HMGN3,NOTUM,CRABP2,TRIB2,AIP,HMGXB4,PPP2R3A,FZD6,CD109,CARD8,ADORA1,ADRBK1,LLGL2,CDK16,BMP7,UBE2J1,BUB1,FAIM,IQGAP3,SYK,MYO5A,HES1,FBLN5,RHOA,PSMB4,ASPM,PLAUR,GCLC,NR4A1,SYBU,RC3H2,LITAF,PPARA,RGCC,PRICKLE1,STMN3,PELI3,BCAR1,BBS2,FOXL1,MAPK8IP1,CTSL,ARHGAP24,HLA-B,BANK1,SWAP70,TWSG1,SCG2,PRCP,NMI,NETO2,ARRB1,UACA,PPP2R3C,NDFIP1,HIPK3,L1CAM,ARHGEF9,CD33,ARHGEF4 |
| 7.485e-18 | -39.43 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 398 | 98 | 17758 | 1761 |
PLA2G4A,SPRED1,IL15RA,IL15,TRIP10,C5orf30,COL18A1,IL13RA1,IL18,F11R,SNN,KREMEN1,TNFSF9,CMTM6,CDS1,RCN1,SETDB2,ZFP36,SLC44A1,IRF2,MINPP1,F2R,SNX10,TIPARP,TIAM1,XKR8,MX1,GCA,PCGF5,RIPK2,SERTAD3,EZR,CD40,ASB13,ALCAM,ADRBK2,SOCS3,NFIX,PTPRJ,C19orf66,RBL1,SECTM1,NFKBIZ,DDX58,ARHGEF3,FRMD4A,TBC1D1,UBASH3B,SDC4,MIER3,C6orf106,HMGN3,GPSM2,LMNA,ZDHHC21,OTUD1,CA2,IGSF9,ITGB8,CTSC,MGAT4A,SGK3,TPST1,DRAM1,TRIM21,TNFRSF12A,PIM1,CITED2,PVRL4,MMD,NR3C1,PLAUR,BCL9,SPATA13,VEZT,FNDC3A,FOS,DCP2,FAS,CD83,DGKH,ENDOD1,PVRL2,PLOD2,RND3,CSF1,TMEM30A,SLC2A6,SPINT2,RAP2C,NLRC5,UACA,ITGAV,ICOSLG,FZD5,IFIH1,KLF7,JARID2 |
| 8.349e-18 | -39.32 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | 1094 | 198 | 17758 | 1761 |
TTC39B,CPT2,HEXB,TAP1,FBXO2,IL18,LYNX1,F11R,FAM101B,SLC20A1,SDC1,PDGFB,PLS3,BTG3,UBE2T,CNTRL,STIM1,ZFP36,SIVA1,FOSB,MITF,AOX1,AKR1B1,SNX16,ACOX2,TINAGL1,TIPARP,S100A13,CD55,CITED4,CELSR2,USP18,MCFD2,PRKRA,ICMT,IDH1,RNF19B,STK17B,PGF,ANKRD10,PIAS3,CARHSP1,PLEKHG6,HS6ST1,WIPI1,GDE1,PLK2,BMP1,ARRDC1,SP6,ITPKA,RAP1GAP,GLCCI1,CAPN1,PRSS8,LASP1,PARP12,NFKBIE,SERPINE2,PEX6,TBC1D1,ITGA6,DNAJB2,DGKQ,ISYNA1,TSPAN7,ELF3,GNS,DOPEY2,ZNRF2,VASN,EXOC8,TMEM51,PCYOX1,DAPK1,ZRANB1,SLC12A2,MMD,PQLC3,TESK1,CORO2A,LPGAT1,HMG20B,TCF7,NPC2,IFIT3,TP53INP2,PCTP,STX3,CDK5R1,FAS,MAPKAPK2,MMP15,CSF1,MDH1,CDK18,LTBP2,MAL2,JAK3,IFIH1,RUSC1,EHD1,SPC25,UPF3B,IL15,NLRX1,ST14,INPP5D,DDIT4L,MORC4,COL18A1,KCTD12,CD274,DDR1,BCAP31,PDGFA,ATP6V0B,SCNN1A,SP100,DOK4,LMO4,SRR,IFIT1,OAS3,ECE1,SIRT1,MX1,PPIF,DRAP1,PTGER4,UTRN,IGSF8,FZD7,ATP13A2,TAPBP,WFS1,OVOL1,KLF5,SLC27A1,IRF7,TM2D2,CPEB4,ENO2,CKAP2,ARMC7,GDF15,CRABP2,SPR,EFNB1,TEAD3,LGALS3BP,DNAJB9,SAC3D1,SGPL1,RNF128,LLGL2,GTF2F2,DRAM1,TRIM21,FAM102A,ARVCF,ADAM15,TSPAN13,ERBB3,CITED2,TPCN1,OSGIN1,MYO5A,FAH,OPLAH,ARAP2,ALDH2,PSMB4,CRB3,GUSB,NR4A1,NUB1,LITAF,AK4,BCAR1,RNPEP,FOS,GPLD1,FUCA1,ENDOD1,GALNT3,ACADSB,PRCP,NMI,PGRMC1,OTUB2,SH3BGRL2,CENPE,HMGA1,CMPK2,FZD5,AHR,DCBLD1 |
| 9.169e-18 | -39.23 | large_cell | COSMIC cancer mutations | large_cell | 15622 | 1647 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.091e-17 | -39.06 | single-organism cellular process | biological process | GO:0044763 | 11471 | 1316 | 16441 | 1675 |
AK7,SLC25A13,HEXB,RET,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,ENPP1,CARHSP1,PLCG1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,ITGA6,MTL5,RAB23,GPSM2,COX6C,HPCAL4,TTYH3,ATG4A,TFAP4,FRY,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,MYDGF,PANX2,ULBP2,DGKG,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,REC8,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PSMA4,GNA11,SFXN5,SLC4A4,ETS2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,DOCK9,NQO1,INPP5D,CD82,PTTG1,C5orf30,GRK6,MGST2,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,DLG3,RASGEF1A,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,SEPT6,HTATIP2,XRCC6BP1,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,MAPK12,CTHRC1,CKAP2,SDC4,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,BAX,KLC3,IGFBP2,PARP9,ACBD5,PVRL4,OPLAH,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,TLL2,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,ITPR2,MGAT5B,SPTB,FANCI,PLS3,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,KCNMB4,AGPAT2,HOXA9,KLF11,MYL12B,RRAGD,RUNX2,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,DPYSL5,PCDH1,RGMB,MGAT4B,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,SLC2A6,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,ZDHHC23,CDH3,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTPRJ,IDE,ABHD12,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CPEB4,KLHL13,HAL,CDCA8,GDF15,AIP,DNAJB9,FZD6,NRP2,M6PR,ZDHHC21,CD109,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,HES1,FBLN5,RHOA,PLAUR,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,SLC35D2,TXN,SSH1,LGR4,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,SERINC2,KCNS3,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,SPATA18,ACVR1C,SLC35C1,KIF13A,POR,PRIM1,PRDM5,BMP1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,THEMIS2,TMEM55B,HERC6,TNFRSF19,S100A2,TSPAN7,MESDC2,C9orf69,RALGPS2,BHLHE41,RPL39,PPP4R1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,ADCK3,LPGAT1,CALM1,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,MATN2,FAM83D,SFMBT1,CABIN1,KLK7,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,ST14,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,FOXJ2,PANK1,KIF1C,ATP1B1,RAD17,PKMYT1,PYGO1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,COBL,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,ADGRB2,SLC25A36,RASSF8,E2F7,GNB5,FJX1,FUT8,DRAM1,CD9,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,FBXO9,DIAPH2,YES1,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,SIVA1,CEP78,TRPC1,CTTN,BTBD3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,BVES,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,HLA-C,C10orf54,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,ELK3,PODXL2,VWA1,PDE5A,NUBP1,MFSD7,RANBP9,STEAP1,UAP1,TMEM30A,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,CCNE2,DYNLRB1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ARTN,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,EPB41L4B,CHP1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,COL4A5,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,RRBP1,MYO5A,B3GALT6,PGM1,CFAP46,RC3H2,RGCC,NADK2,TTC7A,RUNX3,FOXL1,LEPR,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,CD33,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,NRG2,IL18,MORF4L2,SYTL4,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,PQLC2,PSMD1,CYP2S1,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,APOBEC3G,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,ICMT,CYP4F3,COL12A1,PGF,DNM1L,LIMK1,MRPS28,ARF6,E2F8,GAB1,ALDH6A1,NFKBIE,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,GNS,FAM13B,NEK2,NCAM1,NDUFA12,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,CYB5A,STK17A,PTPRF,NCOA3,SEMA4D,SETD3,ITPR1,AURKA,MDH1,NDE1,ARPC2,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,ETS1,GSTP1,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,SIGIRR,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,SDC1,SHC3,CNTRL,ELF5,DUSP10,ANO4,TLN2,TRAM1,MYBL1,S100A13,NEB,CD55,ING1,MCTP1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,H1F0,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,AVPI1,NF2,UGP2,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,LHX6,PLCG2,SRR,EGLN3,MINPP1,SCN2A,GM2A,DVL2,CTH,SIRT1,TIMP2,EVA1A,MBP,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,COL9A3,PACSIN2,MFSD14B,ADGRG1,CD63,DAP,GNE,BLVRB,SWI5,PSMD10,SELL,GABRG2,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,ABCD1,FAIM,TLE6,FAH,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,CD83,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,UBE2C,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,CTGF,ELMO2,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,PACSIN1,RCAN3,XKR8,LAMP2,ORAI2,KIFC2,PBK,CASP9,TNS1,AGO4,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,HLF,SLC25A4,PLK2,GNPTAB,PTER,NKD1,DHTKD1,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,NDUFA4,SLC1A3,ISYNA1,KIAA1161,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,MMD,MICB,AMER1,ANO6,PIP4K2C,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,SLC4A3,FGD6,NR4A2,MAP3K5,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,RPS6KA1,CAST,IQGAP1,CD274,AIFM2,MNS1,APLP2,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,H2AFV,NIN,CMTM7,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,APOBEC3H,CYB561,SPR,LGALS3BP,TEAD3,SIX4,SNTA1,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,SHMT1,ARAP2,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,PGM2L1,GRIN2D,GPER1,ARSB,NCAPG2,SLC25A38,OCLN,JARID2,EXPH5,EMX1,CASP3,NMRK1,LTBP1,CPT2,CAMKK1,CACNB4,DNER,KREMEN1,TMC1,PTCHD4,SH3KBP1,ABCD4,CHPF,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,DLG1,AKR1B1,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,STRIP2,ROR1,MRPS36,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,UEVLD,ADIPOR1,RAP1GAP,GRN,FAM213B,PIFO,LRRFIP2,PEX6,PHLPP1,CA2,KCNN4,DIAPH2-AS1,FXYD5,KDELR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,GLCE,FECH,GNAS,BCAR3,ONECUT1,NUDT16,SLC6A6,PLPP3,UTP14C,CGREF1,CDCA5,NFKBIA,RHOBTB2,PITPNA,YOD1,EGFL7,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,SLC25A48,SS18,SVBP,SETDB2,FRYL,ZDHHC12,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,AES,NOTUM,POMGNT1,SAC3D1,IL17RB,ADORA1,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,GCLC,NR4A1,DEPDC4,ASPM,OGDHL,HLA-B,DHRS2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 1.438e-17 | -38.78 | regulation of cell communication | biological process | GO:0010646 | 2931 | 430 | 16441 | 1675 |
TXN,LGR4,RET,CACNA2D2,NRG2,PSME1,IL18,SYTL4,PJA2,SLC20A1,CARD10,GRM5,CALM2,DAPK2,SESN3,PSMD1,CTGF,CABP1,RGS3,IL31RA,KCNS3,CRY2,RCAN3,TIAM1,METAP2,TNIP1,ACVR1C,SH3BGRL,PBK,SLC35C1,PRKAR2B,ICMT,SLC25A5,POR,ARHGEF26,ABR,ANKRD10,ENPP1,PLCG1,SLC25A4,DNM1L,ANKRD6,PLK2,TRAF3IP1,NKD1,FAM110C,NOD2,HDAC1,EIF4EBP2,TMOD2,ITPKA,ARF6,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,LZTS1,FGD1,CDKN1C,SCOC,NUAK1,ITGA6,SOX9,RAB23,SLC1A3,TNFRSF19,KIAA1161,LMNA,MECOM,TFAP4,ITGA3,RALGPS2,CYR61,PIK3AP1,RIMS3,VASN,FAM13B,DAPK1,MAP3K9,SORL1,TNFRSF12A,MYDGF,CACNA1D,PIKFYVE,NCAM1,RIMS2,GPR161,SOCS5,KLK5,CALM1,AMER1,PIP4K2C,NPHP3,PSMA4,PLIN5,STX3,RASA1,FAS,NCOA3,SEMA4D,PELI2,ITPR1,FAM83D,FGD6,NR4A2,GDF11,MAP3K5,RUSC1,XDH,ARHGAP11A,SPRED1,NLRX1,TRIP10,THRA,INPP5D,DDIT4L,RALBP1,IQGAP1,RGS20,GRK6,BCL2L1,MVB12B,PRKACA,APC2,ZFYVE9,EPS8L2,CCND1,NOV,APLP2,ST5,RNF220,SP100,DACT1,DAB2IP,PDE4D,RASGEF1A,LGMN,CDKN2D,MYT1,NR2C1,RIPK2,FZD4,PRKCQ,ITPR3,FZD7,IRS2,JAK1,WFS1,SLC9A6,AXL,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,NRG1,RGS14,CTHRC1,ARHGEF3,NKX3-1,IGFBP6,EPS8,PDIA3,PKN1,GSTP1,ARHGEF40,FGF19,NEO1,CTNNBIP1,GNB5,CTSC,PTEN,BAX,PLEKHF1,TMBIM6,SLC44A2,IGFBP2,MAPK11,ERBB3,CITED2,TRIM62,SPRY2,NCOA2,FARP2,RASGRF1,TGIF1,ARAP2,ARHGEF28,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,FURIN,FBXO9,GPLD1,CNTNAP1,FGFR2,ACVRL1,SYT7,DBI,TBX18,RYK,GRIN2D,ITGAV,GPER1,LRRK1,FZD5,SIGIRR,LTBP1,ILDR1,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,PDGFB,SLC8B1,ERP29,KREMEN1,TRIM68,SPTB,SH3KBP1,ARHGEF10L,SIPA1L2,NPNT,SHC3,ARHGEF37,IL6ST,SIVA1,TSPAN6,PASK,DLG1,AKR1B1,DUSP10,CTTN,SLC39A10,PTPRE,MYRIP,S100A13,RASGRP1,CYP1B1,CD55,TRIM8,ITCH,USP18,EZR,KLK6,ARHGDIB,PRKRA,SESN1,CDK1,RHEB,OPTN,CXXC4,PLEKHG6,ARHGEF19,KCNMB4,GPRC5B,AGPAT2,HPSE,MADD,RAB11FIP1,PRKCDBP,ADIPOR1,RAP1GAP,RRAGD,PRKAA2,LASP1,RUNX2,BMF,ARAP3,PPP1R2,LGALS3,SERPINE2,RASA2,UBASH3B,PDCL,CALM3,PHLPP1,DHRS3,FBLN1,IL18R1,ANO1,CA2,IGF1R,GATA2,KCNN4,MDFIC,C10orf54,WNT3A,ZRANB1,ALS2CL,MDFI,CYP26B1,SPATA13,STRADB,PDE5A,C3orf58,RANBP9,G2E3,CDK5R1,GNAS,MAPKAPK2,ONECUT1,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,RHOBTB2,EGFL7,JAK3,TOB1,IFI6,AFAP1,RNF146,SORBS1,AVPI1,NF2,FOXM1,IL15,PSME2,TP53,ERBB2,EMP2,BCAP31,ARHGEF16,CYP26A1,IER3,TTC21B,PDGFA,KIF14,BCL6,CDH3,TWIST1,DIXDC1,F2R,DVL2,FRS3,CTH,CHP1,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,AKT1,FIGNL1,S100A4,CDC20,ERBB2IP,DUSP4,CD40,MAP3K6,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,SECTM1,TLE1,EFNA5,IRF7,SPTBN5,ABCA1,ARFGEF3,GCLM,PINK1,ADGRG1,CD63,TSPAN15,ARHGEF11,LRP4,PSMD10,TGFBR1,AES,GDF15,HMGN3,NOTUM,CRABP2,TRIB2,AIP,HMGXB4,PPP2R3A,FZD6,CD109,KIF5B,CARD8,ADORA1,ADRBK1,LLGL2,CDK16,BMP7,BUB1,FAIM,IQGAP3,SYK,MYO5A,HES1,RHOA,RAB3B,PSMB4,ASPM,PLAUR,GCLC,RC3H2,SYBU,LITAF,PRICKLE1,STMN3,PELI3,FOXL1,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,PRCP,NETO2,UACA,ARRB1,SPCS3,NDFIP1,L1CAM,ARHGEF9,HIPK3,ARHGEF4 |
| 2.148e-17 | -38.38 | LEE_BMP2_TARGETS_UP | MSigDB lists | LEE_BMP2_TARGETS_UP | 703 | 143 | 17758 | 1761 |
EXPH5,LTBP1,GAA,ACACB,ATP8A1,FAM102B,NDRG2,IL18,NENF,ITPR2,EPCAM,SESN3,NPNT,METTL7A,RGS3,AOX1,SERINC2,IRF2,CRY2,RAB20,NTN4,SMARCA2,CITED4,USP18,CBX6,EZR,SESN1,ARHGEF26,EDNRA,WIPI1,KCNK1,LRIG1,BMP1,WBSCR27,TRAF5,RRAGD,GRN,CD99,PRSS8,BMF,ZNF395,ALDH6A1,MECOM,CA2,COL6A1,DAPK1,C10orf54,MYLIP,IGSF3,DDB2,PRSS23,ADCK3,PDE5A,FRMD4B,SCARB2,H1F0,PELI2,MATN2,CTSA,PLD1,MAL2,PLIN3,PER3,SERPINB1,IFIH1,RUSC1,REPS2,ST14,DDIT4L,CAST,CD82,THRA,HDAC11,COL18A1,SLC7A2,OSR2,EMP2,DDR1,CYP39A1,TMPRSS4,IER3,PDGFA,APOBEC3B,CDH1,VAT1,GLB1L2,ACSL4,NOTCH3,TSPAN1,CTDSP2,NAGA,C6orf1,TIMP2,COL6A2,SLC39A8,SAT1,ATP1B1,H2AFV,ALCAM,FZD7,GABARAPL1,TAPBP,WFS1,ABCA1,FBLIM1,PINK1,IGFBP6,DAP,ESRP1,BLVRB,EPS8,SDC4,ARL4C,EFHD2,H1FX,FZD6,TMCC3,DTX3L,RNF128,MLPH,ITGB8,BMP7,KLF9,GCNT1,NFE2L3,SUN2,OPLAH,FBLN5,PLSCR1,PIK3R1,COL7A1,LEPR,CRISPLD2,FUCA1,NR1D2,NMI,SPINT2,DTX4,ABCB1,OTUB2,LRRK1,TBC1D4,RGMA |
| 3.175e-17 | -37.99 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14582 | 1563 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,ERI2,GDF15,HMGN3,LBR,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,NGFRAP1,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,IER5L,DEPDC1,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,ARHGEF37,ANKFN1,CEP78,TRPC1,CTTN,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,SNX30,LMO7,CCNE2,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,SRPX2,TIPRL,PDIA4,NEO1,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,MAPK11,WWP1,NPTXR,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,TRIM2,GNPDA1,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,ZNF462,PCGF5,MCTP1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,SLC20A1,NCS1,SESN3,CTGF,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,APOBEC3H,SEPP1,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,SAMD9,PHLPP1,ZNF432,AIM1L,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.175e-17 | -37.99 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14582 | 1563 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,ERI2,GDF15,HMGN3,LBR,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,NGFRAP1,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,IER5L,DEPDC1,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,ARHGEF37,ANKFN1,CEP78,TRPC1,CTTN,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,SNX30,LMO7,CCNE2,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,SRPX2,TIPRL,PDIA4,NEO1,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,MAPK11,WWP1,NPTXR,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,TRIM2,GNPDA1,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,ZNF462,PCGF5,MCTP1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,SLC20A1,NCS1,SESN3,CTGF,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,APOBEC3H,SEPP1,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,SAMD9,PHLPP1,ZNF432,AIM1L,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.258e-17 | -37.96 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 16161 | 1685 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.678e-17 | -37.41 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15548 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.678e-17 | -37.41 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15548 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.678e-17 | -37.41 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15548 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.678e-17 | -37.41 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15548 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.014e-17 | -37.35 | classic | COSMIC cancer mutations | classic | 15549 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.561e-17 | -37.26 | protein binding | molecular function | GO:0005515 | 10510 | 1218 | 16491 | 1673 |
HEXB,RET,TGOLN2,ISOC2,LACTB2,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TIAM1,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,RAB23,GPSM2,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,MAP3K9,MYDGF,ZMYM1,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PYM1,ERO1A,ELK1,NPHP3,PCTP,GNA11,PSMA4,PLIN5,SLC4A4,ETS2,RAET1L,S100A5,CLMN,STK39,GDF11,TMEM159,NUP58,TMEM173,RUSC1,DOCK9,TPRN,NQO1,INPP5D,CD82,PTTG1,C5orf30,GRK6,MVB12B,REPS1,APPBP2,RCN1,MUC16,CDH1,SH3BP1,LRP11,DLG3,ZNF365,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,SEPT6,PTPN9,SAT1,HTATIP2,GTF2A2,SNX12,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,ISOC1,MAPK12,CTHRC1,TCAF1,ESRP1,DCAF7,SDC4,HABP4,BTN3A1,CTSZ,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,CST3,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,PVRL4,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,CXorf57,CNTNAP1,RPL12,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,ACOT7,BCAM,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,F11R,NENF,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NPNT,IL6ST,MITF,PASK,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,TRIM9,PLEKHG6,KCNMB4,KLF12,HOXA9,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,KIF13B,TBCD,SELK,AHCY,PIM1,WNT3A,DPYSL5,RGMB,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,COL13A1,P4HA3,NLRC5,PLD1,SEMA3A,CCNB2,SMCO4,HOXB7,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,PDGFA,LMO4,BCL6,PLK4,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,STK38,EFNA5,IRF7,SYT13,BIN1,ZMAT1,PINK1,CPEB4,CDCA8,GDF15,HMGN3,LBR,AIP,VPS26A,DNAJB9,FZD6,SH2D4A,NRP2,CD109,FOXP2,CDK16,ALPP,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,COL7A1,BBS2,TXNDC11,SCG2,SH3BGRL2,ICOSLG,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,STIM1,OSBPL3,PALD1,FOSB,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SPATA18,ACVR1C,KIF13A,LDB2,POR,ANKRD10,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,THEMIS2,S100A2,PSIP1,MESDC2,C9orf69,LYPD3,BHLHE41,VASN,PPP4R1,DAPK1,TMEM51,PRKG1,OSTF1,CACNA1D,SYTL3,SOCS5,TRAK2,KLK5,ADCK3,CALM1,NPC2,EPHA1,ANTXR1,JADE2,MMP15,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,AGBL5,FAM83D,SFMBT1,CDK18,CABIN1,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,REPS2,THRA,DDIT4L,CCDC110,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,ZFYVE9,EPS8L2,NOV,ACAP2,BRI3,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,UTRN,KIF1C,ATP1B1,RAD17,PKMYT1,PYGO1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TRIOBP,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,HERC5,FBXO6,EFNB1,FGF19,HLA-A,WWP2,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,PDGFC,TGIF1,ZWINT,LONRF3,ZC3H11A,FBXO9,DIAPH2,YES1,AIF1L,FOS,KIF11,DCTN6,CDK5RAP1,TIMP3,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,SIVA1,TRPC1,CTTN,MYRIP,CENPA,ITCH,USP18,TYSND1,GPRC5B,HPSE,MADD,CAB39,ZNF165,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,PYROXD2,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,COL6A1,LIMCH1,HLA-C,ZRANB1,SLC12A2,ETV7,GAD1,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,NUBP1,PDIK1L,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,KCTD9,ARTN,KIF14,REEP1,DIXDC1,ECE1,EPB41L4B,SEPHS1,CHP1,PTPRU,C3orf52,CD40,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,INTS8,TRIB2,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ARVCF,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RGCC,NADK2,RUNX3,TCEAL8,LEPR,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,ARRB1,UACA,GRAMD1C,MCUR1,CEP41,PLOD3,AHR,RAB3IL1,CD33,ABCG1,ACACB,IL15RA,ADD1,DNAJC3,FBXO2,NRG2,DHX8,IL18,SYTL4,MORF4L2,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,CYP2S1,CABP1,ALDH1A3,KLF3,TUBG1,ACOX2,MANF,TINAGL1,PIK3CD,SEMA3G,APOBEC3G,SMARCA2,TNIP1,SH3BGRL,LOXL2,F12,ICMT,PGF,DNM1L,LIMK1,SERPINB6,ARF6,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,SOX9,MERTK,LMNA,ELF3,GNS,NEK2,NCAM1,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,CYB5A,DCP2,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,ARPC2,FBXO27,NDE1,ZNF502,EGLN1,XDH,MTM1,GRHL2,TMSB15A,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CCND1,RNF220,SCNN1A,SP100,DACT1,RAB27B,ARL4D,CDKN2D,SSH3,CAMSAP3,FZD4,CYS1,SYNE2,PLEKHO1,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,PKN1,NUCB2,TMA16,ARHGEF40,GSTP1,ETS1,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,CTSC,ANKS1B,ALG13,CALD1,TMBIM6,ADAM15,ECI2,PLEKHF1,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,UNKL,MYL9,SIGIRR,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,SDC1,NUP62CL,PDGFB,CNTRL,SHC3,MKRN3,ANO4,TLN2,TRAM1,S100A13,NEB,PCGF5,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,PRKAA2,BMF,HLA-F,UBASH3B,CNTNAP2,IL18R1,IGF1R,GATA2,EXOC8,MDFIC,C9orf9,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,EPN3,MAPKAPK2,PVRL2,H1F0,CSF1,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,AVPI1,UGP2,UPF3B,NF2,FOXM1,ERBB2,CCDC68,RAD23A,PLCG2,LHX6,SRR,EGLN3,DVL2,CTH,SIRT1,MBP,TIMP2,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,C19orf66,PTK7,ANXA9,LTA4H,CMTM4,PACSIN2,MACC1,ADGRG1,CD63,RUSC2,DAP,GNE,SWI5,PSMD10,SELL,GABRG2,NKRF,CRABP2,SIRPA,PPP2R3A,CCDC92,ABCD1,BUB1,FAIM,FAH,DLGAP1,HMMR,PSMB4,CRB3,IFITM3,NR3C1,AMFR,PPARA,LITAF,PELI3,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,FAT4,SERPINA1,TWSG1,CDCA7L,NMI,PGRMC1,NETO2,CLIP4,PPP2R3C,GUCD1,UBE2C,NDFIP1,DIS3L,SUN1,PPP4R4,TTC39B,ATP8A1,TAP1,CCNB1,FAM101B,NCS1,CTGF,ELMO2,PRICKLE3,IQCE,ZFP36,RGS3,IL31RA,PACSIN1,RCAN3,LAMP2,ORAI2,KIFC2,SNTB2,PBK,CASP9,TNS1,AGO4,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,AHRR,SLC25A4,PLK2,GNPTAB,NKD1,FAM110C,SARAF,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,C6orf106,KIF23,NDUFA4,ISYNA1,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EPB41L5,DDB2,MFI2,MICB,AMER1,ANO6,PIP4K2C,VEZT,RASA1,STX3,FAS,GABRD,PRKAG2,DCK,CSNK1G1,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,SLC2A4,CEP70,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,RNF182,CD274,TMPRSS4,MNS1,APLP2,FAM46A,DOK4,CDKN1B,DAB2IP,IFIT1,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,LINC01588,H2AFV,SP4,NIN,CMTM7,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,MLKL,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ARL4C,APOBEC3H,CYB561,TEAD3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,TAGLN2,CNOT6L,CNPY3,SPRY2,OSGIN1,NCOA2,RASGRF1,SHMT1,MPP1,PARP4,FURIN,C1GALT1C1,NUCB1,AMMECR1,CSTF2,GRIN2D,GPER1,NCAPG2,OCLN,ESYT2,EXPH5,EMX1,CASP3,NMRK1,LTBP1,CAMKK1,CACNB4,DNER,DENND2D,KREMEN1,SH3KBP1,CHPF,C7orf49,LRRC6,ZCCHC12,TSPAN6,DPYSL2,DLG1,POF1B,SUN3,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,PTGFRN,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,ADIPOR1,RAP1GAP,GRN,PIFO,LRRFIP2,PEX6,SAMD9,PHLPP1,CA2,KCNN4,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,OXR1,GYLTL1B,HMG20B,RNF113A,GNAS,FECH,BCAR3,NUDT16,PLPP3,CDCA5,NFKBIA,YOD1,EGFL7,GAS2L1,SPC25,FAM92A1,IL15,MORC4,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,GCA,IGSF8,ERBB2IP,KCTD2,BFSP1,BHLHB9,PEX2,REEP4,LIFR,ANXA3,SORT1,FRMD6,POC1B,LRP4,ARMC7,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,MLPH,ADORA1,KIAA0319,IQGAP3,SUN2,RAB3B,NR4A1,GCLC,ASPM,OGDHL,MBNL3,KLHL2,HLA-B,HNRNPH2,PRCP,DHRS2,OTUB2,GEM,SOX8,L1CAM,SNPH |
| 7.564e-17 | -37.12 | medulla | COSMIC cancer mutations | medulla | 15553 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 8.010e-17 | -37.06 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15554 | 1639 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 9.935e-17 | -36.85 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 17034 | 1740 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.025e-16 | -36.82 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 808 | 156 | 17758 | 1761 |
EXPH5,CASP3,SLC35D2,TRIM2,EPAS1,TMEM41B,TGOLN2,PJA2,SLC20A1,PDGFB,SDC1,FAM46C,CMTM6,EPCAM,CDKN2C,BTG3,DPYSL2,OSBPL3,IL6ST,PHTF1,ALDH1A3,SLC44A1,SERINC2,RCAN3,BTBD3,CYP1B1,LAMP2,ORAI2,SMARCA2,TRIM8,SNTB2,CASP9,ROR1,GALNT7,MCFD2,ANLN,SESN1,ARF4,MDK,MID1IP1,SLC25A4,HPSE,GPRC5B,KCNK1,ZNF367,FAM114A1,DHTKD1,KLF11,ITPKA,MAFF,E2F8,STARD3NL,CDKN1C,SCOC,PDCL,SLC36A4,ISYNA1,DHRS3,TTYH3,ANO1,BMP2K,ELF3,UBE2Q2,ITGA3,KCNN4,VASN,LIMCH1,NCEH1,ZRANB1,SLC12A2,GPR161,KIF20A,LPGAT1,ANO6,SPTLC2,PDIK1L,ANTXR1,C3orf58,RANBP9,GNA11,DCP2,GNAS,EPN3,PRPS2,AURKA,STK39,SHROOM2,TMEM173,SLC25A24,GRHL2,NF2,FOXM1,CAST,RALBP1,ATP2C2,GRK6,DDR1,PHLDA1,ARHGEF16,CDS1,RCN1,CCND1,EPB41L4B,F2R,ETV4,SNX10,MED30,SUSD3,SEC23A,TMTC1,FZD4,SYNE2,IGSF8,H2AFV,DAG1,ALDH5A1,SLC9A6,VSIG10,KLF5,REEP4,ST3GAL1,PRR15,ABCA1,CMTM4,IER5L,ANXA3,CTHRC1,PINK1,PACSIN2,IGFBP6,AES,CTSZ,LBR,SIX4,VPS26A,GNB5,FAIM,SGCB,SYK,CRTAP,HMMR,TACC1,AMFR,PRICKLE1,AIF1L,ARSK,GALNT3,NR1D2,AMMECR1,SPINT2,RAP2C,HOXB13,CEP41,PTGES,ESYT2,ABCG1 |
| 1.093e-16 | -36.75 | COLDREN_GEFITINIB_RESISTANCE_DN | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_DN | 217 | 65 | 17758 | 1761 |
EXPH5,LMO7,GRHL2,REPS2,ST14,ATP2C2,PRSS22,DDR1,TMPRSS4,EPS8L2,CDS1,WEE1,AP1M2,CDH1,GRHL1,NPNT,ALDH1A3,ENPP5,CLDN4,CDH3,TACSTD2,MYH14,TSPAN1,SMAGP,ENPP4,GCA,KLK6,ARHGDIB,RAB38,KCNMB4,RBM47,CCDC149,OVOL1,CAB39,ANXA9,GAB1,PRSS8,MACC1,FXYD3,SRPX2,PRRG4,ZDHHC21,ELF3,AIM1L,AIM1,KLC3,ERBB3,PVRL4,ARAP2,TBC1D8B,PDE5A,EPHA1,FRMD4B,GNAS,EPN3,ENDOD1,GALNT3,TMEM54,TJP3,TMC5,STK39,SH3BGRL2,MAL2,GRAMD1C,OCLN |
| 2.036e-16 | -36.13 | anatomical structure development | biological process | GO:0048856 | 4662 | 621 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,CACNA2D2,NRG2,IL18,GRM5,CDKN2C,CALM2,WEE1,PSMD1,PAQR5,ALDH1A3,CLDN4,PIK3CD,SEMA3G,TIAM1,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,HDAC1,TMOD2,ITPKA,ARF6,E2F8,GAB1,HOXC13,SCN5A,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,PAQR7,REC8,SALL4,NPHP3,PSMA4,GNA11,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,CLMN,AURKA,GDF11,CFAP20,DRP2,NDE1,ARPC2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,C5orf30,PKP2,PRKACA,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,WFS1,CORO1C,AXL,SIPA1L1,PNPLA6,TRABD2A,RGS14,MAPK12,TTC8,CTHRC1,TNRC6C,NKX3-1,SDC4,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,SGPL1,NEO1,CTNNBIP1,IGSF9,ITGB8,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,SGCB,S100A6,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,CRISPLD2,CNTNAP1,PITX2,ACVRL1,DBI,NR4A3,ITGAV,FHL1,OSR1,USF2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,DZIP1L,DPYSL3,HS6ST1,AGPAT2,MAP2,HOXA9,MAFF,MYL12B,RUNX2,LGALS3,RASA2,NCKAP1,CNTNAP2,DHRS3,IL18R1,TNS3,DAZAP1,IGF1R,GATA2,KIF13B,FRAS1,WNT3A,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,G2E3,PRX,CDK5R1,FOXD2,MAPKAPK2,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,ERBB2,STIL,IER3,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,TIMP2,MBP,AKT1,S100A4,CDC20,PTGER4,MYL12A,DAG1,DUOX1,PTPRJ,PTK7,EFNA5,LTA4H,BIN1,COL9A3,PACSIN2,CDH22,ADGRG1,PSMD10,GDF15,CRABP2,FZD6,PPP2R3A,NRP2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,SYK,TLE6,GCNT1,HES1,RHOA,PSMB4,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,FAT4,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,LGR4,SSH1,HSPG2,TMEM41B,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,TACSTD2,RCAN3,ZBTB18,PACSIN1,SGCE,CASP9,LDB2,SAV1,CCNF,ZFAND5,ARHGEF26,HLF,PTER,PLK2,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,UNC5B,TANC2,F2RL1,LZTS1,FGD1,SEMA6B,CDKN1C,SLC25A27,SLC1A3,HERC6,TNFRSF19,KIAA1161,MECOM,MESDC2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,RIMS2,IGSF3,EPB41L5,KLK5,MMD,CALM1,ANO6,AMER1,VEZT,EPHA1,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,MATN2,FAM83D,PCDH19,KLK7,NR4A2,HOOK1,EHD1,SPRED1,FOXO6,TCTN2,ST14,THRA,IQGAP1,RPS6KA1,CAST,BCL2L1,DDR1,APLP2,NOV,DOK4,CNNM4,CDKN1B,DAB2IP,EPHB4,PDE4D,SEMA3B,FOXJ2,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,CEP162,EPHA10,JAK1,NRG1,KLF5,CBX7,COBL,WASF3,HAPLN3,CENPI,PBX3,SEPP1,SPR,EFNB1,FGF19,ADGRB2,SIX4,TEAD3,SCML1,E2F7,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,TAGLN2,CITED2,SPRY2,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,C1GALT1C1,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,JARID2,RGMA,EXPH5,EMX1,CASP3,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,GRHL1,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,RP2,CTTN,MYH14,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,EDNRA,MDK,CXXC4,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,CA2,COL6A1,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,SOX13,BCAR3,GNAS,FECH,ONECUT1,TMEM30A,PLPP3,ALPK3,PITPNA,EGFL7,SHROOM2,JAK3,RARG,KLF7,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,PHLDA1,SS18,SETDB2,ARTN,FRYL,KIF14,DIXDC1,TWIST1,ECE1,F2R,FRS3,MAP3K3,PTPRU,OSTM1,GLO1,IGSF8,DUSP4,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,SECTM1,PTBP3,TLE1,OVOL1,SPTBN5,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,CIT,FRMD6,LRP4,COL4A5,AES,TGFBR1,HDAC9,TOP2A,KIF5B,MDM1,ADRBK1,ADORA1,LLGL2,MYCL,BMP7,TOX2,KIAA0319,MYO5A,CFAP46,NR4A1,ASPM,RC3H2,TTC7A,RUNX3,FOXL1,ARHGAP24,SWAP70,PRCP,DHRS2,CTSV,RAP2C,SPINT2,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,AHR,L1CAM |
| 2.400e-16 | -35.97 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 694 | 139 | 17758 | 1761 |
MYL9,LTBP1,TXN,PPFIBP2,CACNA2D2,NDRG2,IL18,TP53I11,SYTL4,FAM101B,SDC1,LTBP3,ZNF275,PLS3,DAPK2,BTG3,CTGF,TSPAN6,FOSB,MITF,RAB20,TINAGL1,RCAN3,PACSIN1,S100A13,CYP1B1,SMARCA2,SGCE,CR2,SESN1,STK17B,AHRR,HLF,GPRC5B,MAP2,PLK2,HOXA9,PRDM5,PRKCDBP,NFKBIZ,CDKN1C,DNAJB2,ABCG2,NCKAP1,PHLPP1,IL18R1,CYR61,GATA2,PAIP2B,AIM1,COL6A1,TPST1,SORL1,MDFIC,LIMCH1,NCAM1,DGKG,SLC12A2,ABCC1,PAQR7,PQLC3,PRSS23,TESK1,STAT4,NFIB,SLC6A6,ETS2,NFKBIA,MATN2,NR4A2,LTBP2,ZDBF2,SERPINB1,IFIH1,TOB1,SNX30,IL15,HDAC11,COL18A1,PHLDA1,IER3,PDGFA,CCND1,DAB2IP,EPHB4,EPB41L4B,IFIT1,DLG3,F2R,SNX10,SLC39A8,S100A4,PTGER4,PRKCQ,RAB38,DUSP4,CD40,ALCAM,CASP4,GABARAPL1,NFIX,SOCS3,ARHGAP35,PDLIM3,JAK1,C19orf66,MMP17,TLE1,IRF7,ABCA1,COL9A3,NKX3-1,FRMD6,LRP4,EPS8,PBX3,CTSZ,DNAJB9,LGALS3BP,GNB5,CALD1,RRBP1,KLF9,CITED2,NPTXR,S100A6,WBP5,IFITM3,NR4A1,RC3H2,STMN3,YES1,FOS,TIMP3,FHL1,GEM,L1CAM,PKIA,ABCG1 |
| 2.563e-16 | -35.90 | multicellular organismal development | biological process | GO:0007275 | 4594 | 613 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,NRG2,IL18,GRM5,CDKN2C,CALM2,WEE1,PSMD1,PAQR5,ALDH1A3,KLF3,CLDN4,PIK3CD,SEMA3G,TIAM1,TIPARP,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,LIMK1,ATP7B,TRAF3IP1,HDAC1,TMOD2,ITPKA,ARF6,GAB1,E2F8,HOXC13,SCN5A,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,PAQR7,REC8,SALL4,NPHP3,PSMA4,GNA11,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,ITPR1,CLMN,AURKA,GDF11,CFAP20,DRP2,NDE1,ARPC2,XDH,ADAMTS16,EGLN1,PAPSS2,GRHL2,INPP5D,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,CORO1C,WFS1,AXL,SIPA1L1,PNPLA6,RGS14,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,DCAF7,SDC4,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,SGPL1,NEO1,CTNNBIP1,IGSF9,ITGB8,CST3,BAX,ADAM15,TMBIM6,WWP1,SGCB,S100A6,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,CRISPLD2,CNTNAP1,PITX2,ACVRL1,DBI,NR4A3,CENPE,ITGAV,FHL1,OSR1,USF2,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,DPYSL3,HS6ST1,MAP2,HOXA9,MAFF,MYL12B,RUNX2,LGALS3,RASA2,NCKAP1,CNTNAP2,FBLN1,DHRS3,ANO1,IL18R1,TNS3,DAZAP1,IGF1R,GATA2,KIF13B,FRAS1,PIM1,WNT3A,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,G2E3,PRX,CDK5R1,MAPKAPK2,COL13A1,PHLPP2,CSF1,ITGA7,PRPS2,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,ERBB2,STIL,EMP2,PDGFA,TTC21B,LMO4,PLCG2,LHX6,SRR,BCL6,PLK4,CDH3,NOTCH3,MINPP1,SCN2A,DVL2,SULF2,SIRT1,TIMP2,MBP,AKT1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,DUOX1,IDE,PTPRJ,PTK7,EFNA5,LTA4H,BIN1,COL9A3,CDH22,ADGRG1,GABRG2,PSMD10,CRABP2,FZD6,PPP2R3A,NRP2,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,SYK,TLE6,GCNT1,HES1,RHOA,PSMB4,PPARA,STMN3,PRICKLE1,COL7A1,FNDC3A,BBS2,PRDX4,FAT4,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,HSPG2,SSH1,LGR4,VANGL1,TMEM41B,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,TACSTD2,ZBTB18,PACSIN1,SGCE,CASP9,LDB2,SAV1,CCNF,ZFAND5,HLF,PLK2,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,UNC5B,TANC2,F2RL1,LZTS1,FGD1,SEMA6B,CDKN1C,SLC25A27,SLC1A3,HERC6,TNFRSF19,KIAA1161,MECOM,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,EPB41L5,MMD,CALM1,ANO6,AMER1,VEZT,EPHA1,NFIB,STX3,RASA1,FAS,MMP15,MATN2,FAM83D,PCDH19,NR4A2,HOOK1,EHD1,SPRED1,FOXO6,ST14,THRA,IQGAP1,CAST,RPS6KA1,BCL2L1,DDR1,MNS1,APLP2,NOV,DOK4,CNNM4,CDKN1B,DAB2IP,EPHB4,PDE4D,GPX4,SEMA3B,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,EPHA10,JAK1,NGFRAP1,NRG1,KLF5,PRR15,CBX7,COBL,WASF3,PCOLCE,HAPLN3,CENPI,PBX3,SEPP1,SPR,FGF19,EFNB1,ADGRB2,SIX4,TEAD3,E2F7,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,CITED2,SPRY2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,JARID2,RGMA,EXPH5,EMX1,CASP3,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,GRHL1,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,CTTN,MYH14,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,ARHGDIB,EDNRA,MDK,CXXC4,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,CA2,COL6A1,SUCO,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,BCAR3,GNAS,FECH,ONECUT1,TMEM30A,UTP14C,PLPP3,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,APOL2,RARG,KLF7,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,PHLDA1,SETDB2,ARTN,FRYL,KIF14,DIXDC1,TWIST1,ECE1,FRS3,MAP3K3,PTPRU,OSTM1,GLO1,IGSF8,CD40,DUSP4,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,PTBP3,TLE1,OVOL1,SPTBN5,LIFR,ANXA3,SORT1,ARHGEF11,CIT,LRP4,COL4A5,AES,TGFBR1,HDAC9,TOP2A,KIF5B,MDM1,ADRBK1,ADORA1,LLGL2,MYCL,BMP7,TOX2,KIAA0319,ARVCF,MYO5A,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FOXL1,LEPR,ARHGAP24,SWAP70,PRCP,DHRS2,CTSV,SPINT2,ARRB1,HOXB13,PLOD3,SOX8,ZMIZ1,AHR,L1CAM |
| 3.586e-16 | -35.56 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 790 | 152 | 17758 | 1761 |
KIAA1462,EPAS1,VANGL1,TEX2,MPP5,PDGFB,CARD10,ZFYVE16,CTGF,SHC3,DPYSL2,IL6ST,KLF3,PIK3CA,TRPC1,NTN4,SEMA3G,TIPARP,BTBD3,MGAT5,CD55,HSPA12A,LOXL2,LDB2,ARHGEF26,COL12A1,OPTN,SERPINI1,GLCCI1,NXT2,LASP1,PARP12,SCOC,CDKN1C,PPP1R2,CHCHD7,TBC1D1,RASA2,SLC36A4,PHLPP1,MERTK,ATG4A,UBE2Q2,FRY,ZNRF2,VASN,PRKG1,EXOC8,C8orf58,SLC12A2,MAST4,TRAK2,MMD,BTNL9,HEATR5A,SPTLC2,ANKRD29,RANBP9,C3orf58,PRX,TMEM30A,PELI2,NFKBIA,SFMBT1,YOD1,PLD1,SHROOM2,TOB1,ADAMTS16,LMO7,MTM1,LZTFL1,SORBS1,ARMCX3,UGP2,CAST,CTDSPL,IL13RA1,KBTBD11,ARHGEF16,ACAP2,ST5,FAM46A,FRYL,PDE4D,ACSL4,TMEM64,SULF2,SEMA3B,DOCK4,ENPP4,MAP3K3,TMTC1,COQ10B,PTGER4,DOCK5,PTPRJ,JAK1,SHROOM3,PLEKHG1,VSIG10,HS3ST3B1,SLC27A3,LIFR,PRR15,PCOLCE,CPEB4,FRMD6,COL4A5,TRIB2,ETS1,EFNB1,SIRPA,SH2D4A,TMCC3,KIF5B,FOXP2,AKIRIN1,ITGB8,SGK3,ARVCF,CCDC82,FAM102A,ATP8B1,SGK1,CITED2,ACBD5,PHF20L1,ARAP2,PLSCR1,MOSPD2,TACC1,RC3H2,PARP4,MBNL3,DIAPH2,C1GALT1C1,YES1,FNDC3A,AIF1L,ENDOD1,ARHGAP24,TIMP3,PLOD2,ABCB1,UACA,ARRB1,SH3BGRL2,GEM,HIPK3,CPEB2,JARID2 |
| 5.067e-16 | -35.22 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 1022 | 183 | 17758 | 1761 |
LTBP1,UGT8,TRIM2,KIAA1462,ATP8A1,TEX2,ITPR2,DNER,SDC1,CMTM6,ABCD4,CPNE2,SESN3,RGS3,IQCE,CEP78,SLC44A1,ABCA2,ANKRD12,DUSP10,PTPRE,ATL1,SMARCA2,KCNIP3,KIFC2,EZR,TMEM151A,TNS1,KIF13A,ICMT,CCNF,ZFAND5,LHFPL2,DPYSL3,LRRC42,MFAP3L,HLF,WIPI1,GNPTAB,NKD1,LRIG1,BMP1,SERPINI1,UNC5B,GAB1,E2F8,BMF,UBASH3B,SLC1A3,ATG4A,RALGPS2,SPIN4,COL6A1,TMEM51,SORL1,RFX5,NCEH1,CCDC88A,FAM69A,ADCK3,LPGAT1,PIP4K2C,NPC2,SPTLC2,TP53INP2,C3orf58,CYB5A,FRMD4B,SOX13,SCARB2,SLC6A6,COQ10A,ETS2,SEMA4D,ITGA7,TMEM30A,CSF1,SETD3,MATN2,SH3BP4,CLMN,PCDH19,CABIN1,GDF11,MAP3K5,PER3,SHROOM2,TMEM14A,COL16A1,AFAP1,RUSC1,SNX30,DOCK9,EHD1,LZTFL1,SLC25A24,SORBS1,TCTN2,REPS2,CD82,DDR1,TNFSF9,CYP39A1,PDGFA,FAM46A,ZDHHC12,REEP1,ENPP5,VAT1,DIXDC1,PDE4D,EPB41L4B,LMAN1,ZNF365,NAGA,MYO5B,DOCK4,CLCN3,MBP,TIMP2,COL6A2,CAPN6,OSTM1,SAT1,CDCA2,PRKCQ,DNAJB14,ERBB2IP,H2AFV,ALCAM,ATP13A2,SOCS3,ALDH3B1,CDK19,ABHD12,AXL,CORO1C,PLEKHG1,CBX7,GLIS3,ZMAT1,TNRC6C,PINK1,PCOLCE,POC1B,LRP4,EPS8,COL4A5,FBXO6,PARM1,NEO1,HDAC9,TMEM63A,WWP2,TMCC3,SGPL1,FOXP2,ADD3,RNF128,ITGB8,LYPD6,CD9,FAM63A,FAM102A,SGCB,AMOTL2,ACBD5,PDGFC,MOSPD2,PPARA,C1GALT1C1,PRICKLE1,BCAR1,FOS,TIMP3,SMTNL2,NR1D2,FGFR2,RAB11FIP2,SOX8,ARSB,AHR,CPEB2 |
| 5.313e-16 | -35.17 | endomembrane system | cellular component | GO:0012505 | 3658 | 500 | 17570 | 1756 |
SUN1,LAMP1,SLC35D2,ACACB,KLK10,HSPG2,IL15RA,MRPS15,ATP8A1,DNAJC3,HEXB,RET,TAP1,FBXO2,TGOLN2,SYTL4,VASH1,PJA2,SLC9A7,NCS1,CYP1A1,AP1M2,MUC4,CTGF,STIM1,CABP1,OSBPL3,CYP2S1,STEAP2,KCNS3,FUT1,TUBG1,SNX16,MARCH2,PACSIN1,MGAT5,ERAP2,LAMP2,SPEF2,SGCE,SNTB2,SLC35C1,KIF13A,GALNT7,ICMT,MCFD2,CYP4F3,POR,ARF4,COL12A1,DNM1L,GNPTAB,ATP7B,BMP1,SARAF,ARF6,F2RL1,FGD1,SCN5A,FAM169A,NFKBIE,SCOC,GGA1,TMEM55B,HLA-E,RAB23,FAM21C,KIAA1161,LMNA,MESDC2,MECOM,MARCH8,DOPEY2,SNX18,ZNRF2,FLRT3,RANBP1,TPST1,PRKG1,SORL1,MYDGF,PIKFYVE,NCAM1,SYTL3,NUP85,C9orf72,PPP6R1,GPR161,FAM69A,TRAK2,FADS2,B3GNT7,KLK5,PQLC3,MMD,KIF20A,LPGAT1,ERO1A,PIP4K2C,VEZT,NPC2,ATP8B3,ANTXR1,SPTLC2,GLT8D2,STX3,CYB5A,DGKH,AP1AR,FAAH,ITPR1,FGD6,KLK7,MAL2,ARPC2,MAP3K5,PLIN3,NRBP1,NUP58,TMEM173,RUSC1,XDH,EHD1,DOCK9,PLA2G4A,MTM1,SLC2A4,CEP70,TRIP10,GALNT12,CAST,CCDC110,ATP2C2,RGS20,MGST2,BCL2L1,CD274,MVB12B,PRKACA,APC2,CYP39A1,MNS1,REPS1,ZFYVE9,CDS1,RCN1,MUC16,ACAP2,CDH1,XYLT2,CDKN1B,PDE4D,ACSL4,LGMN,RAB27B,SULT2B1,SNX10,TMEM9,SEMA3B,GPX4,MYO5B,MX1,DOCK4,SEC23A,SEC61B,COL6A2,COG2,SYNE2,PANK1,KIF1C,HTATIP2,SLC11A2,PKMYT1,DNAJB14,RAB38,ITPR3,TRIQK,SNX12,ATP10D,GABARAPL1,JAK1,DDOST,STK26,WFS1,SLC9A6,PNPLA6,SLC27A1,KLF5,HS3ST3B1,NR3C2,IGFBP6,ATP9A,SDC4,PDIA3,CTSZ,FBXO6,PKN1,NUCB2,HLA-A,PDIA4,SGPL1,NEO1,AKIRIN1,GOLGA2P5,FUT2,RNF128,CTSC,ARSG,ALG13,MGAT4A,FAM20B,CST3,FUT8,SGK3,CD9,BAX,ATP8B1,PLEKHF1,ADAM15,TMBIM6,CNPY3,TPCN1,S100A6,CRTAP,AMOTL2,PDGFC,B3GNT2,PLSCR1,BCL9,RAPGEF2,PIK3R1,ELOVL3,EIF5A2,GRIN1,FURIN,C1GALT1C1,DIAPH2,YES1,NEURL1B,FOS,ARSK,CPTP,CRISPLD2,GALNT3,NUCB1,PLOD2,FGFR2,RAB11FIP2,SYT7,DBI,ERAP1,GPER1,FZD5,ARSB,ESYT2,RGMA,EXPH5,EPHA4,ARFGEF1,NDRG2,DNAJB11,NENF,MPP5,ITPR2,MGAT5B,PDGFB,NUP62CL,SDC1,ERP29,DNER,TRIM68,ABCD4,CHPF,ZFYVE16,RAB15,RPS6KA2,GRHL1,METTL7A,IMPAD1,PHTF1,PASK,ABCA2,DLG1,DUSP10,SUN3,RAB20,RP2,CTTN,SCARA3,TECR,TRAM1,MYRIP,RASGRP1,LAMP3,CYP1B1,ATL1,KCNIP3,STAU2,NFE2L1,EZR,KLK6,ARFRP1,PTGFRN,RHEB,OPTN,DPYSL3,MAN2A2,HS6ST1,AGPAT2,MAP2,KCNK1,WIPI1,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,GLA,NRGN,RAP1GAP,PCSK5,STARD3NL,RRAGD,PIFO,FAM213B,BMF,LMTK3,SERPINE2,FXYD3,HLA-F,RAB6A,CNTNAP2,B4GALT4,ADAMTSL4,DHRS3,B4GALNT1,B3GALNT1,COL6A1,EXOC8,SUCO,SELK,MDFIC,HLA-C,FAR2,WNT3A,NCEH1,MPHOSPH9,ALDH3A2,CCDC88A,CKAP4,SNX7,C9orf9,KDELR1,CYP26B1,CHSY3,MGAT4B,GYLTL1B,EMC2,C3orf58,STEAP1,GLCE,GNAS,EPN3,H1F0,COL13A1,PLPP3,TMEM30A,MFSD2A,P4HA3,SH3BP4,ZDHHC7,CTSA,PLD1,TMEM120A,JAK3,APOL2,COL16A1,NIPA1,SNX30,NF2,IL15,P3H2,XYLT1,PDIA5,TP53,COL18A1,ERBB2,FAM198B,LPIN3,EMP2,BCAP31,CYP26A1,SYTL2,PDGFA,ATP6V0B,WDR44,CYP4F11,ZDHHC12,REEP1,ZDHHC23,RPN2,ECE1,NOTCH3,TMEM64,MINPP1,LMAN1,F2R,PDIA6,SCYL3,SEPHS1,CHP1,SULF2,CPD,SIRT1,CLCN3,ERLEC1,EVA1A,C3orf52,ACO1,ERBB2IP,CASP4,DNAJC10,TAPBP,ATP1A1,SECTM1,IRF7,SYT13,CYP2U1,REEP4,AIFM3,ST3GAL1,ABCA1,NDST3,ARFGEF3,GLIS3,COL9A3,ANXA3,SORT1,PACSIN2,GOLIM4,CPEB4,CD63,TGFBR1,COL4A5,NKRF,CRABP2,DSE,POMGNT1,LBR,VPS26A,PARM1,DNAJB9,ZDHHC21,M6PR,ADORA1,CDK16,A4GALT,RRBP1,KIAA0319,TFAP2A,UBE2J1,SGK1,MYO5A,GCNT1,B3GALT6,SUN2,SYPL1,RAB3B,RHOA,IFITM3,AMFR,NR4A1,PLAUR,SYBU,LITAF,PRICKLE1,STMN3,MAML2,COL7A1,FNDC3A,TXNDC11,RNPEP,MAPK8IP1,PRDX4,CTSL,HLA-B,SERPINA1,RND3,SCG2,DHRS2,CTSV,RAP2C,PGRMC1,ARRB1,SPCS3,PLOD3,NDFIP1,PTGES,ABCG1,GOLGB1 |
| 8.531e-16 | -34.70 | locomotion | biological process | GO:0040011 | 1396 | 235 | 16441 | 1675 |
MYL9,LAMP1,EPHA4,HEXB,RET,NRG2,F11R,PSME1,PLXNA1,CACNB4,PDGFB,SDC1,DNER,CMTM6,SPTB,SH3KBP1,CALM2,TYMP,PSMD1,RPS6KA2,LRRC6,CTGF,SHC3,ELMO2,SIVA1,DPYSL2,MITF,PIK3CA,DLG1,TRPC1,NTN4,MYH14,SEMA3G,PIK3CD,CTTN,TIAM1,RASGRP1,CYP1B1,CD55,CELSR2,STRIP2,ITCH,CR2,EZR,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,DPYSL3,MDK,PLCG1,LIMK1,UNC5B,F2RL1,MYL12B,SEMA6B,SCN5A,LGALS3,BVES,ITGA6,RASA2,CALM3,NCKAP1,S100A2,MERTK,TNS3,ITGA3,CYR61,GATA2,MEGF8,FLRT3,COL6A1,PRKG1,TNFRSF12A,CACNA1D,NCAM1,ZRANB1,WNT3A,NUP85,CCDC88A,EPB41L5,DPYSL5,PODXL2,RGMB,CALM1,ANO6,SPATA13,STRADB,SCRIB,EPHA1,PSMA4,RANBP9,NFIB,RASA1,CDK5R1,PTPRF,SCARB2,SEMA4D,PVRL2,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,PITPNA,ATP1B3,PLD1,NDE1,ARPC2,SHROOM2,SEMA3A,JAK3,KLF7,SPRED1,INPP5D,RPS6KA1,PSME2,RALBP1,ERBB2,EMP2,APC2,DDR1,ARHGEF16,PDGFA,NOV,ARTN,LHX6,DAB2IP,DIXDC1,TWIST1,PDE4D,EPHB4,RASGEF1A,DLG3,TSPAN1,ETV4,SCYL3,FRS3,SEMA3B,DOCK4,COL6A2,FZD4,SYNE2,PRKCQ,ATP1B1,ALCAM,MYL12A,DAG1,ARHGAP35,CMTM7,EPHA10,IRS2,IDE,PTPRJ,JAK1,AXL,PTK7,CORO1C,PEX2,EFNA5,SPTBN5,NRG1,CMTM4,COL9A3,CTHRC1,CD63,ADGRG1,ARHGEF11,EPS8,SDC4,PSMD10,SELL,TGFBR1,COL4A5,PKN1,ETS1,DNAH3,SRPX2,EFNB1,FGF19,SIX4,NRP2,SIRPA,WWP2,NEO1,SGPL1,KIF5B,CXCL16,ADRBK1,PTEN,BMP7,FUT8,KIAA0319,BAX,WWP1,ERBB3,SYK,MYO5A,PARP9,FARP2,GCNT1,PVRL4,HES1,RASGRF1,B3GNT2,RHOA,ARHGEF28,PSMB4,CFAP46,ASPM,RAPGEF2,PLAUR,NR4A1,PIK3R1,GRIN1,YES1,BCAR1,GPLD1,CNTNAP1,PITX2,ARHGAP24,FGFR2,SCG2,ACVRL1,NR4A3,RYK,PGRMC1,GRIN2D,ITGAV,SOX8,ARSB,L1CAM,RGMA |
| 1.069e-15 | -34.47 | bladder | COSMIC cancer mutations | bladder | 14810 | 1576 | 17775 | 1757 |
HECA,AK7,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,TTYH3,RABGGTA,ATG4A,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,ST5,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,ETV4,MX1,TMEM200B,COL6A2,C6orf1,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,GTF2A2,SNX12,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,WFS1,CORO1C,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,ZFAND4,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,UBE2A,CXorf57,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NPNT,IL6ST,PAPSS1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,TMEM164,HS6ST1,PLEKHG6,KCNMB4,KLF12,AGPAT2,HOXA9,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,RUNX2,PARP12,HJURP,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,GLB1L2,NOTCH3,OAS3,LMAN1,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,ABHD12,RBL1,MMP17,STK38,EFNA5,IRF7,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDH22,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,DNAJB9,H1FX,SH2D4A,FZD6,NRP2,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SSH1,HSPG2,LGR4,VANGL1,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,BHLHE41,RPL39,VASN,PPP4R1,AIM1,DAPK1,TPST1,ADCK2,PRKG1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,PELI2,MATN2,AGBL5,FAM83D,SFMBT1,CABIN1,CDK18,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,PANK1,UTRN,TMEM144,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,CBX7,COBL,IER5L,DEPDC1,HAPLN3,CENPI,EPS8,PBX3,HERC5,EFHD2,FBXO6,DNAH3,FGF19,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FJX1,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,METTL7A,ARHGEF37,SIVA1,CEP78,ANKFN1,TRPC1,CTTN,MYRIP,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ADAMTSL4,COL6A1,LIMCH1,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,VWA1,HEATR5A,NUBP1,PDIK1L,C3orf58,RANBP9,MFSD7,STEAP1,UAP1,TMEM30A,SH3BP4,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,LZTFL1,NCKAP5,DYNLRB1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,ECE1,EPB41L4B,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,FOXL1,LEPR,ENDOD1,ARHGAP24,SWAP70,RND3,TRIM69,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,CEP41,PLOD3,AHR,RAB3IL1,CD33,ABCG1,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,LYNX1,MORF4L2,SYTL4,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,PQLC2,AP1M2,CABP1,CYP2S1,ALDH1A3,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SMARCA2,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,ARF6,E2F8,GAB1,HOXC13,NFKBIE,FAM169A,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,TIMM8A,SEMA4D,SETD3,ITPR1,AURKA,MDH1,NDE1,DRP2,FBXO27,ARPC2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,PRSS22,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,PLEKHG1,INPP4B,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,GSTP1,ARHGEF40,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,NKAPP1,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,GALNT3,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,DCBLD1,MYL9,SIGIRR,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,DDX59,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,C3orf18,IL18R1,DAZAP1,IGF1R,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,MAPKAPK2,EPN3,COQ10A,H1F0,PVRL2,ITGA7,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,EGLN3,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,RUSC2,GNE,GABRG2,PSMD10,SELL,NKRF,DSE,SIRPA,PPP2R3A,SLC9A2,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,IGDCC4,HMMR,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,CCDC34,PELI3,FNDC3A,BCAR1,MAPK8IP1,BSDC1,SCRN2,PRDX4,CDKN2AIPNL,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,CDCA7L,TMC5,NMI,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,SESN3,CTGF,ELMO2,IQCE,PRICKLE3,ZFP36,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,HSPA12A,CASP9,NBPF3,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,RBM47,PLK2,GNPTAB,NKD1,FAM110C,DHTKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,PRRG4,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,FADS2,B3GNT7,DDB2,PMPCB,MMD,ZNF84,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,BROX,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CNNM4,CDKN1B,DAB2IP,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,NIN,PRDM11,CMTM7,EPHA10,PPP2R5A,JAK1,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,LGALS3BP,TEAD3,SIX4,TMCC3,SNTA1,AKIRIN1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CCDC69,PGM2L1,CSTF2,GRIN2D,ETAA1,ARSB,NCAPG2,SLC25A38,OCLN,ESYT2,JARID2,EXPH5,EMX1,LTBP1,CASP3,NMRK1,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,KREMEN1,TMC1,SH3KBP1,ABCD4,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,TSPAN6,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,POF1B,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,STK17B,ADRBK2,EDNRA,CXXC4,LRRC42,NEIL1,ARHGEF19,ZNF114,UEVLD,ADIPOR1,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,AIM1L,ZNF432,CA2,KCNN4,RFX5,NCEH1,SIMC1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,RNF113A,AMDHD1,MUM1L1,GLCE,FECH,GNAS,XKRX,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,PROM2,GAS2L1,SLC25A24,FAM92A1,SPC25,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,SUSD3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,PPP2R2D,SORT1,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,IL17RB,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,LRRC66,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 1.069e-15 | -34.47 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14810 | 1576 | 17775 | 1757 |
HECA,AK7,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,GTF2A2,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,LYNX1,MORF4L2,SYTL4,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,MYL9,SIGIRR,TRIM2,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,NKRF,DSE,SLC9A2,PPP2R3A,SIRPA,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,PRDX4,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,RBM47,PLK2,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,GAS2L1,SLC25A24,SPC25,FAM92A1,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,SORT1,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.240e-15 | -34.32 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1762 | 293 | 16036 | 1726 |
LAMP1,ACACB,HECA,SSH1,TSC22D3,SLC25A13,TMEM41B,FAM102B,PJA2,DPP8,SLC20A1,BARD1,FAM46C,CMTM6,NCS1,SESN3,CTGF,OSBPL3,ALDH1A3,SNX16,MARCH2,ZBTB18,LAMP2,TMEM68,SNTB2,SERTAD4,TFAP2C,SAV1,ICMT,SLC25A5,ARF4,PIAS3,ANKRD10,RBM47,LIMK1,ATP7B,EIF4EBP2,TRAF5,NXT2,FGD1,NUAK1,C6orf106,TTYH3,MECOM,TFAP4,ZNRF2,SLC16A6,FAM13B,RANBP1,CD70,OSTF1,C9orf72,PAQR7,TRAK2,GFPT1,MMD,PRSS23,SALL4,LPGAT1,MICB,ANO6,CALM1,AMER1,PIP4K2C,VEZT,ELK1,ANTXR1,NFIB,GNA11,DCP2,AP1AR,NCOA3,PRKAG2,SEMA4D,DCK,SETD3,NR4A2,MAL2,TMEM159,FBXO27,SPRED1,TCTN2,CAST,C5orf30,RNF182,IL13RA1,CCND1,APLP2,FAM46A,DOK4,CDKN1B,EPHB4,ACSL4,DLG3,SNX10,SZRD1,FOXJ2,PANK1,NUSAP1,ATP1B1,H2AFV,NIN,IRS2,STK26,AXL,CORO1C,SLC9A6,INPP4B,TRIOBP,EFCAB14,KLF5,ISOC1,DEPDC1,SDC4,OSGIN2,EFHD2,FAM217B,SLC25A43,ETS1,PDIA4,NEO1,SGPL1,SCML1,CTNNBIP1,AKIRIN1,DTX3L,CXCL16,GNB5,SLC27A6,PTEN,FAM20B,CD9,CITED2,SPRY2,SLC16A5,TGIF1,BCL9,FURIN,AK4,YES1,LRRC1,AIF1L,KIF11,AMMECR1,RYK,ARSB,WDR45B,JARID2,EXPH5,CCNI,CASP3,TRIM2,EPAS1,FAM199X,CNOT8,FLYWCH2,CUL4B,DNAJB11,F11R,HDAC6,NUP62CL,SH3KBP1,METTL7A,DPYSL2,SLC44A1,MITF,TRPC1,CTTN,SLC39A10,BTBD3,TRAM1,TRIM8,ING1,STAU2,ITCH,CBX6,EZR,IDH1,KCNK1,DOLPP1,ADIPOR1,KLF11,PXDC1,STARD3NL,PARP12,ZNF395,PPP1R2,SERPINE2,LRRFIP2,UBASH3B,ETV5,PDCL,CALM3,PM20D2,RAB6A,PHLPP1,DHRS3,UBE2Q2,DAZAP1,GATA2,SPIN4,EXOC8,LIMCH1,PIM1,DESI2,CKAP4,CYP26B1,STRADB,GLCE,FECH,MAPKAPK2,UAP1,TMEM30A,PRPS2,YOD1,TMEM14A,TOB1,IFI6,LZTFL1,CTDSPL,TP53,OSR2,PHLDA1,KCTD9,SS18,WDR44,EFR3A,REEP1,EPB41L4B,LMAN1,DVL2,GM2A,CTH,CHP1,FRS3,SEPHS1,CPD,SIRT1,GCA,OSTM1,COQ10B,C3orf52,FANCE,DAG1,SOCS3,TAPBP,PTBP3,VSIG10,LTA4H,TMEM263,BIN1,MFSD14B,GOLIM4,SORT1,ARHGEF11,CIT,GNE,CDCA8,AES,TGFBR1,COL4A5,DNAJB9,FZD6,VPS26A,CCDC92,IRF2BPL,CARD8,UBE2J1,TFAP2A,SGK1,ABCD1,TSPAN13,KLF9,IQGAP3,C12orf75,HES1,MOSPD2,NR3C1,GCLC,AMFR,PLAUR,RC3H2,LITAF,NADK2,FNDC3A,TCEAL8,CDCA7L,RAP2C,NETO2,GUCD1,UBE2C,ZBTB33,ABCG1 |
| 1.298e-15 | -34.28 | kidney | COSMIC cancer mutations | kidney | 16177 | 1682 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.918e-15 | -33.47 | VECCHI_GASTRIC_CANCER_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_EARLY_UP | 388 | 91 | 17758 | 1761 |
ILDR1,KLK10,IL15RA,DLGAP5,S100A11,FOXM1,PTTG1,NDC80,DHX8,NUF2,LACTB2,CCNB1,AIFM2,NUP62CL,BARD1,TMPRSS4,CENPN,FANCI,UBE2T,KIF14,CDH3,TACSTD2,SLC39A10,RASGEF1A,CKS2,TMEM68,CENPA,FIGNL1,PBK,CDC20,TFAP2C,KLK6,NUSAP1,CDCA2,F12,ANLN,CDK1,ANKRD10,ABHD12,HOXA9,ZNF367,OVOL1,KLF5,MRPS28,PIEZO1,HSPB1,E2F8,GRN,IER5L,DEPDC1,MACC1,CKAP2,GDF15,GPSM2,SAC3D1,IL17RB,TOP2A,E2F7,SPIN4,KCNN4,RANBP1,TFAP2A,CD9,NEK2,BUB1,FAR2,GAD1,S100A6,HMMR,ZWINT,MFI2,KIF20A,IFITM3,ASPM,MYBL2,MYEOV,FAM133B,COL7A1,GGH,SCRIB,CDCA5,TMC5,PGRMC1,AURKA,KLK7,HMGA1,NCAPG2,UBE2C,CCNB2,IFI6,MELK |
| 3.871e-15 | -33.19 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1782 | 276 | 17758 | 1761 |
HSPG2,VANGL1,FBXO2,MORF4L2,CAMK1D,CALM2,WEE1,SESN3,ELMO2,STIM1,RGS3,CABP1,FOSB,STEAP2,KCNS3,MANF,LAMP2,SMARCA2,ACVR1C,SNTB2,SH3BGRL,SERTAD4,PRKAR2B,SAV1,LDB2,RNF19B,PIAS3,NKD1,BMP1,EIF4EBP2,SERPINI1,ARF6,F2RL1,HSPB1,SCN5A,CDK17,ALDH6A1,CALB2,SOX9,RAB23,C6orf106,ISYNA1,SLC1A3,MERTK,TNFRSF19,TSPAN7,LMNA,MECOM,TFAP4,CYR61,SLC16A6,FLRT3,CACNA1D,PIKFYVE,MAST4,MYLIP,MMD,TBC1D8B,CALM1,NPC2,NFIB,SFXN5,DGKH,PTPRF,NCOA3,AP1AR,PRKAG2,NR4A2,CDK18,STK39,ARPC2,HOOK1,SLC2A4,ARMCX3,GRHL2,REPS2,RALBP1,C5orf30,RNF182,CD274,GRK6,SNN,REPS1,APPBP2,CDS1,RNF220,CDH1,DACT1,XYLT2,ACSL4,PDE4D,ETV4,MYT1,DOCK4,CAPN6,SYNE2,CDCA2,PYGO1,ALCAM,SP4,FZD7,PDLIM3,AXL,NRG1,HS3ST3B1,PRIMA1,NR3C2,CBX7,PRR15,IER5L,SDC4,PBX3,NUCB2,SEPP1,SRPX2,HOXB2,PDIA4,WWP2,DTX3L,ADD3,RNF128,PTEN,ANKS1B,CALD1,FAM20B,MAPK11,NPTXR,SPRY2,NCOA2,ACBD5,ADAMTS2,TGIF1,ARAP2,BCL9,EIF5A2,PIK3R1,UBE2A,LRRC1,FOS,PITX2,NUCB1,TIMP3,FGFR2,NR4A3,OSR1,FZD5,CPEB2,MELK,JARID2,RGMA,LTBP1,TRIM2,PPM1J,HEBP1,ARFGEF1,MPP5,PDGFB,SPTB,SH3KBP1,NKAIN3,RPS6KA2,SHC3,TSPAN6,IL6ST,MITF,TRPC1,DUSP10,RP2,BTBD3,ZNF462,PCGF5,TRIM8,ING1,NFE2L1,RGAG1,ROR1,PTGFRN,SESN1,ZBTB7B,DPYSL3,CXXC4,KLF12,GPRC5B,RRAGD,PCSK5,RMND5A,PRKAA2,LASP1,BMF,LRRFIP2,CHCHD7,ETV5,ASB9,CALM3,CNTNAP2,FAM81A,DHRS3,IL18R1,IGF1R,FRAS1,RFX5,SLC12A2,CCDC88A,MDFI,CYP26B1,ELK3,OXR1,C3orf58,SOX13,GNAS,BCAR3,EPN3,UAP1,COL13A1,H1F0,NFKBIA,SH3BP4,SEMA3A,CCNB2,TOB1,NCKAP5,SORBS1,HOXB7,NF2,UGP2,TP53,ERBB2,FAM198B,BCAP31,KCTD9,SYTL2,CYP26A1,RAD23A,LHX6,BCL6,EGLN3,SEPHS1,MAP3K3,CLCN3,MYL12A,TLE1,EFNA5,REEP4,ST3GAL1,NDST3,CMTM4,TM2D2,PACSIN2,ARHGEF11,POC1B,COL4A5,NRP2,PPP2R3A,ZDHHC21,IRF2BPL,FOXP2,KIF5B,ADRBK1,TOX2,TFAP2A,ARVCF,ABCD1,HES1,MOSPD2,NR3C1,CRB3,PRICKLE1,TCEAL8,PRDX4,SCG2,RAP2C,NETO2,PGRMC1,GEM,UBE2C,DIS3L |
| 4.276e-15 | -33.09 | CHEN_METABOLIC_SYNDROM_NETWORK | MSigDB lists | CHEN_METABOLIC_SYNDROM_NETWORK | 1167 | 199 | 17758 | 1761 |
LTBP1,LGR4,PPM1J,CAMKK1,HEXB,DNAJB11,NDRG2,NANS,LTBP3,CALM2,CDKN2C,RAB15,BTG3,RPS6KA2,TSPAN6,OSBPL3,DUSP10,MTMR11,SEMA3G,PTPRE,LAMP2,CENPA,TNIP1,CBX6,ARHGDIB,PIF1,LOXL2,SESN1,STK17B,ABR,DPYSL3,TMEM164,PLK2,LRIG1,SERPINB6,UNC5B,TRAF5,F2RL1,E2F8,MYL12B,GRN,LASP1,FRMD4A,LGALS3,CHCHD7,TBC1D1,UBASH3B,ASAH1,CALM3,LMNA,ELF3,GNS,CA2,PIK3AP1,RINL,KCNN4,VASN,COL6A1,OPN3,TPST1,TMEM51,FXYD5,CADPS2,AHCY,OSTF1,C10orf54,C9orf9,MDFI,PRODH,MFI2,STAT4,ANO6,CALM1,NPC2,IFIT3,SPTLC2,ANTXR1,STEAP1,RASA1,CACHD1,SLC6A6,FAM64A,SEMA4D,DCK,SLC2A6,MATN2,SLC4A3,FGD6,CDK18,LTBP2,ARPC2,COL16A1,USP43,GAS2L1,PLA2G4A,SPRED1,SLC25A24,SLC2A4,CCDC109B,NQO1,S100A11,INPP5D,C5orf30,CD274,FAM198B,SNN,ZNF385B,CDS1,RCN1,APOBEC3B,ATP6V0B,SCNN1A,SP100,PLCG2,VAT1,CDH3,LGMN,DLG3,RASGEF1A,SEMA3B,SUSD3,C3orf52,PLEKHO1,TMEM144,KIF1C,IGSF8,SLC11A2,PKMYT1,ITPR3,NIN,ATP13A2,ALDH3B1,ABHD12,NGFRAP1,WFS1,NRG1,RGS14,REEP4,SLC27A3,ANXA3,CMAS,SORT1,PCOLCE,CD63,FRMD6,ARMC7,BLVRB,GNE,HAL,EPS8,DSE,HOXB2,SRPX2,LGALS3BP,SIRPA,NRP2,SGPL1,SLC25A36,RASSF8,FAM111A,CXCL16,RNF128,SLC27A6,GALNS,CD9,DRAM1,IGFBP2,TAGLN2,SYK,MYO5A,S100A6,GCNT1,ADAMTS2,FBLN5,PLSCR1,LONRF3,GUSB,FMN1,PLAUR,SYBU,LITAF,PRICKLE1,BLVRA,FOS,GPLD1,CD83,ENDOD1,GALNT3,ACVRL1,PRCP,PPM1H,FHL1,HMGA1,ICOSLG,FZD5,L1CAM,ESPL1,RAB3IL1,ABCG1 |
| 5.376e-15 | -32.86 | vesicle | cellular component | GO:0031982 | 3622 | 491 | 17570 | 1756 |
SUN1,LAMP1,GAA,TXN,KLK10,HSPG2,IL15RA,ATP8A1,DNAJC3,HEXB,FBXO2,TGOLN2,PSME1,IL18,LYNX1,NANS,PLXNA1,SYTL4,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,DAPK2,PSMD1,AP1M2,MUC4,ALDH1A3,STEAP2,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,MARCH2,PACSIN1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,MCFD2,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,DNM1L,PTER,ATP7B,NOD2,BMP1,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,MARCH8,GNS,DOPEY2,ITGA3,SNX18,ZNRF2,ATP5H,MEGF8,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,CADPS2,MYDGF,PIKFYVE,NCAM1,SYTL3,C9orf72,RIMS2,GPR161,GFPT1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,VEZT,NPC2,ATP8B3,TP53INP2,ANTXR1,JADE2,PSMA4,GNA11,STX3,CYB5A,FAS,PTPRF,AP1AR,SCARB2,NCOA3,SLC4A4,ITPR1,MDH1,KLK7,MAL2,ARPC2,CFAP20,SERPINB1,TMEM173,RUSC1,EHD1,PLA2G4A,MTM1,SLC2A4,NQO1,ST14,TRIP10,S100A11,BROX,CD82,IQGAP1,KCTD12,FTH1,BCL2L1,CD274,MVB12B,PRKACA,DDR1,APPBP2,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,ACSL4,EPHB4,TSPAN1,LGMN,RAB27B,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,SEC23A,COL6A2,RIPK2,FZD4,SEPT6,SYNE2,CYS1,UTRN,SLC11A2,ATP1B1,RAB38,ALCAM,H2AFV,SNX12,GABARAPL1,EPHA10,ALDH3B1,STK26,CORO1C,SLC9A6,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,PKN1,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,PDIA4,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,SGK3,CD9,BAX,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,AMOTL2,PVRL4,PDGFC,ALDH2,SHMT1,B3GNT2,PLSCR1,ERMAP,RAPGEF2,GRIN1,PARP4,FURIN,C1GALT1C1,AK4,BLVRA,YES1,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,FGFR2,RAB11FIP2,SYT7,DBI,ABCB1,ERAP1,ITGAV,GPER1,FZD5,ARSB,OCLN,CYBRD1,ACOT7,RGMA,BCAM,CRYM,GNPDA1,HEBP1,CUL4B,NDRG2,F11R,MPP5,PDGFB,SDC1,ERP29,SH3KBP1,SUSD2,EPCAM,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,ABCA2,DLG1,AKR1B1,RAB20,RP2,MYH14,CTTN,MYRIP,NEB,S100A13,SMAGP,LAMP3,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,OPTN,DPYSL3,TRIM9,CXXC4,ZNF114,GPRC5B,KCNK1,UEVLD,WIPI1,RAB11FIP1,CAB39,ARRDC1,PIK3C2B,GLA,NRGN,MYL12B,CAPN1,CPPED1,PCSK5,GRN,PRSS8,LASP1,PIFO,FAM213B,BMF,SERPINE2,LGALS3,HLA-F,FXYD3,CALM3,ASAH1,PM20D2,RAB6A,NCKAP1,FBLN1,ANO1,CA2,RINL,COL6A1,AHCY,HLA-C,WNT3A,GAD1,SLC12A2,ALDH3A2,CCDC88A,CKAP4,SNX7,ABCC1,C9orf9,KDELR1,PCBP3,VWA1,SCRIB,NUBP1,C3orf58,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,TMEM30A,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,PROM2,UGP2,PSME2,CTDSPL,HDAC11,COL18A1,ERBB2,MRAS,EMP2,PHLDA1,BCAP31,SYTL2,PDGFA,ATP6V0B,EFR3A,PLCG2,N4BP3,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,DVL2,CTH,CHP1,CPD,GCA,CLCN3,TIMP2,AKT1,FIGNL1,S100A4,ACO1,GLO1,IGSF8,CD40,MYL12A,DAG1,ATP13A2,PTPRJ,ATP1A1,BHLHB9,SECTM1,SPTBN5,ANXA9,SYT13,ST3GAL1,LTA4H,ABCA1,LIFR,ARFGEF3,MAN2B2,ANXA3,SORT1,PACSIN2,GOLIM4,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FZD6,TMEM63A,KIF5B,TAF1B,MLPH,CDK16,A4GALT,BMP7,GALNS,FAM63A,ALDH7A1,SYK,ATP2B1,MYO5A,FAH,PGM1,SYPL1,FBLN5,RAB3B,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,SYBU,COL7A1,GGH,FNDC3A,RNPEP,SCRN2,PRDX4,ENDOD1,FUCA1,CTSL,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,SCG2,PRCP,DHRS2,CTSV,RAP2C,TMC5,PGRMC1,ARRB1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 6.611e-15 | -32.65 | movement of cell or subcellular component | biological process | GO:0006928 | 1515 | 247 | 16441 | 1675 |
MYL9,TXN,AK7,RET,EPHA4,HEXB,NRG2,F11R,PSME1,PLXNA1,CACNB4,PDGFB,DNER,SDC1,SPTB,SH3KBP1,CALM2,RPS6KA2,PSMD1,LRRC6,CTGF,ELMO2,SHC3,DPYSL2,MITF,DLG1,PIK3CA,TRPC1,NTN4,PIK3CD,CTTN,MYH14,SEMA3G,TIAM1,NEB,RASGRP1,CYP1B1,KIFC2,CELSR2,STRIP2,EZR,ARHGDIB,TNS1,KIF13A,LOXL2,ANLN,ZFAND5,CDK1,ARF4,DPYSL3,MDK,PLCG1,LIMK1,TRAF3IP1,UNC5B,ARF6,HSPB1,F2RL1,MYL12B,SEMA6B,SCN5A,LGALS3,BVES,ITGA6,RASA2,CALM3,KIF23,RAB6A,NCKAP1,MERTK,S100A2,TNS3,ITGA3,CYR61,GATA2,MEGF8,KIF13B,FLRT3,COL6A1,PRKG1,TNFRSF12A,CACNA1D,ZRANB1,NCAM1,WNT3A,MYLIP,NUP85,CCDC88A,EPB41L5,DPYSL5,PODXL2,KIF20A,RGMB,CALM1,ANO6,SPATA13,STRADB,SCRIB,EPHA1,NPHP3,PSMA4,NFIB,RANBP9,RASA1,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,PITPNA,NR4A2,PLD1,ATP1B3,NDE1,ARPC2,SHROOM2,SEMA3A,JAK3,KLF7,DYNLRB1,SPRED1,DLGAP5,INPP5D,RPS6KA1,PSME2,ERBB2,DDR1,EMP2,APC2,ARHGEF16,PDGFA,TTC21B,NOV,ARTN,KIF14,LHX6,DAB2IP,DIXDC1,TWIST1,PDE4D,EPHB4,TSPAN1,DLG3,RASGEF1A,ETV4,SCYL3,FRS3,SEMA3B,DOCK4,COL6A2,SYNE2,KIF1C,IGSF8,PRKCQ,ATP1B1,ALCAM,DAG1,MYL12A,ARHGAP35,EPHA10,IRS2,JAK1,PTK7,CORO1C,AXL,PEX2,SPTBN5,NRG1,EFNA5,COL9A3,CTHRC1,ARHGEF11,ADGRG1,CD63,FRMD6,EPS8,SDC4,SELL,PSMD10,TGFBR1,COL4A5,PKN1,ETS1,DNAH3,EFNB1,FGF19,SRPX2,SIRPA,NRP2,SIX4,SGPL1,NEO1,KIF5B,CXCL16,PTEN,CALD1,BMP7,FUT8,KIAA0319,CD9,KLC3,BAX,ERBB3,SYK,MYO5A,PARP9,FARP2,GCNT1,RASGRF1,HES1,SUN2,RHOA,LCA5,ARHGEF28,B3GNT2,PSMB4,CFAP46,NR4A1,PLAUR,AMFR,RAPGEF2,ASPM,PIK3R1,GRIN1,YES1,BCAR1,KIF11,GPLD1,ARHGAP24,CNTNAP1,PITX2,ACVRL1,FGFR2,SCG2,SPINT2,PGRMC1,RYK,NR4A3,GRIN2D,CENPE,ITGAV,SOX8,ARSB,L1CAM,RGMA |
| 7.343e-15 | -32.55 | developmental process | biological process | GO:0032502 | 5307 | 683 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,CACNA2D2,NRG2,IL18,GRM5,CDKN2C,CALM2,WEE1,PSMD1,PAQR5,ALDH1A3,KLF3,CLDN4,PIK3CD,SEMA3G,TIAM1,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,HDAC1,TMOD2,ITPKA,ARF6,GAB1,E2F8,HOXC13,SCN5A,ALDH6A1,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,PAQR7,REC8,SALL4,ERO1A,NPHP3,ELK1,TP53INP2,PSMA4,GNA11,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,ITPR1,CLMN,AURKA,GDF11,CFAP20,NDE1,DRP2,ARPC2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,NQO1,INPP5D,C5orf30,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,RAB38,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,WFS1,AXL,CORO1C,SIPA1L1,PNPLA6,TRABD2A,RGS14,MAPK12,TTC8,CTHRC1,TNRC6C,NKX3-1,DCAF7,SDC4,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,SGPL1,NEO1,CTNNBIP1,IGSF9,ITGB8,CTSC,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,SGCB,S100A6,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,CRISPLD2,CNTNAP1,PITX2,ACVRL1,DBI,NR4A3,CENPE,HMGA1,ITGAV,FHL1,OSR1,USF2,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,CELSR2,CITED4,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,DZIP1L,DPYSL3,HS6ST1,AGPAT2,MAP2,HOXA9,MAFF,MYL12B,RUNX2,LGALS3,RASA2,CNTNAP2,NCKAP1,FBLN1,DHRS3,IL18R1,ANO1,TNS3,DAZAP1,IGF1R,GATA2,FRAS1,KIF13B,PIM1,WNT3A,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,G2E3,PRX,CDK5R1,FOXD2,MAPKAPK2,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,TMEM120A,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,ERBB2,STIL,EMP2,IER3,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,DUOX1,IDE,PTPRJ,PTK7,EFNA5,LTA4H,BIN1,COL9A3,PACSIN2,CDH22,CD63,ADGRG1,GABRG2,PSMD10,GDF15,CRABP2,FZD6,PPP2R3A,NRP2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,SYK,TLE6,GCNT1,HES1,RHOA,PSMB4,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,FAT4,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,LGR4,SSH1,HSPG2,VANGL1,TMEM41B,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,TACSTD2,RCAN3,ZBTB18,PACSIN1,SGCE,ACVR1C,CASP9,LDB2,SAV1,CCNF,ZFAND5,ARHGEF26,HLF,PTER,PLK2,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,UNC5B,TANC2,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,CDKN1C,SLC25A27,SLC1A3,HERC6,TNFRSF19,KIAA1161,MECOM,MESDC2,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,EPB41L5,KLK5,MMD,CALM1,ANO6,AMER1,VEZT,EPHA1,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,MATN2,FAM83D,PCDH19,SFMBT1,KLK7,NR4A2,HOOK1,EHD1,SPRED1,FOXO6,SLC2A4,TCTN2,ST14,THRA,IQGAP1,RPS6KA1,CAST,BCL2L1,DDR1,MNS1,NOV,APLP2,DOK4,CNNM4,CDKN1B,DAB2IP,EPHB4,PDE4D,MED30,SEMA3B,GPX4,FOXJ2,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,CEP162,EPHA10,JAK1,NGFRAP1,NRG1,KLF5,PRR15,CBX7,COBL,WASF3,PCOLCE,HAPLN3,CENPI,PBX3,SEPP1,SPR,EFNB1,FGF19,ADGRB2,SIX4,TEAD3,SCML1,E2F7,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,TAGLN2,CITED2,SPRY2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,WDR62,NCAPG2,ARSB,SLC25A38,MELK,JARID2,RGMA,EXPH5,EMX1,CASP3,UGT8,MPP5,CACNB4,DNER,TMC1,EPCAM,LRRC6,GRHL1,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,RP2,CTTN,MYH14,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,TRIM8,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,CA2,COL6A1,SUCO,C10orf54,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,SOX13,FECH,GNAS,BCAR3,ONECUT1,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,APOL2,RARG,KLF7,IL15,PSME2,HDAC11,COL18A1,TDRKH,MRAS,OSR2,PHLDA1,SS18,SETDB2,ARTN,FRYL,KIF14,RPN2,DIXDC1,TWIST1,ECE1,F2R,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,SECTM1,PTBP3,TLE1,OVOL1,SPTBN5,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,CIT,FRMD6,LRP4,COL4A5,AES,TGFBR1,HDAC9,IRF2BPL,TOP2A,KIF5B,MDM1,ADRBK1,ADORA1,LLGL2,MYCL,BMP7,TOX2,RRBP1,KIAA0319,ARVCF,MYO5A,CFAP46,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FOXL1,LEPR,ARHGAP24,SWAP70,PRCP,DHRS2,CTSV,RAP2C,SPINT2,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,L1CAM,AHR |
| 8.592e-15 | -32.39 | RUTELLA_RESPONSE_TO_HGF_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_UP | 401 | 92 | 17758 | 1761 |
LAMP1,CASP3,TXN,NQO1,TRIP10,HEXB,IL18,FTH1,TEX2,PLXNA1,BCAP31,CCND1,ZFYVE16,IL6ST,MITF,AKR1B1,VAT1,RAB20,SNX10,GM2A,SEPHS1,LAMP3,CYP1B1,LAMP2,CPD,PPIF,DOCK4,TIMP2,MCTP1,FOXJ2,ACO1,SLC11A2,RAB38,LHFPL2,ADRBK2,OPTN,DUOX1,JAK1,RBM47,GLA,HSPB1,ST3GAL1,GCLM,PACSIN2,PINK1,LGALS3,CD63,TBC1D1,SDC4,C6orf106,ASAH1,SLC1A3,C3orf18,SGPL1,GNS,TNS3,MDM1,LYPD3,SLC16A6,BHLHE41,TPST1,TMEM51,CD9,SGK1,TMBIM6,KLF9,ALDH3A2,FAM69A,FAH,WBP5,GFPT1,SUN2,LITAF,GGH,SNTB1,CYB5A,STK17A,NCOA3,SCARB2,PVRL2,NAT1,ITPR1,NETO2,NR4A3,MDH1,ATP1B3,LTBP2,FZD5,PLOD3,TBC1D4,IFI6,ABCG1 |
| 1.210e-14 | -32.05 | BENPORATH_CYCLING_GENES | MSigDB lists | BENPORATH_CYCLING_GENES | 620 | 124 | 17758 | 1761 |
ARHGAP11A,CCNE2,CASP3,CEP70,DLGAP5,FOXM1,VANGL1,DNAJC3,PTTG1,NDC80,DHX8,NUF2,MORF4L2,GRK6,CCNB1,SDC1,BARD1,STIL,NCS1,KCTD9,FANCI,CCND1,PDGFA,CDKN2C,SS18,HSF2,UBE2T,RGS3,KIF14,LMO4,REEP1,PASK,MITF,CDKN1B,GOT1,IFIT1,PIK3CD,SLC39A10,CDKN2D,BTBD3,CKS2,SEPHS1,PLK1,CENPA,PBK,CYB5R2,PTPN9,CDC20,NUSAP1,ARHGDIB,PIF1,PKMYT1,DUSP4,CCNF,ANLN,ITPR3,KCTD2,RHEB,PRIM1,ANKRD10,PLK2,E2F8,GCLM,HJURP,PPP1R2,CKAP2,DCAF7,CIT,SLC25A27,RAB23,OSGIN2,CDCA8,KIF23,GDF15,GPSM2,LBR,LMNA,DNAJB9,SLC25A36,TOP2A,KIF5B,MDM1,GATA2,NEK2,TFAP2A,SLC44A2,SGK1,BUB1,KLF9,ZMYM1,LRIF1,HMMR,TGIF1,ZWINT,NR3C1,HMG20B,COL7A1,RNF113A,BORA,BBS2,ANTXR1,KIF11,G2E3,DCTN6,NCOA3,FAM64A,H1F0,KBTBD2,CDCA7L,ITPR1,MATN2,FAM83D,AURKA,UACA,DONSON,CENPE,NDE1,PLIN3,WDR62,UBE2C,CCNB2,ESPL1,AFAP1,MELK |
| 1.592e-14 | -31.77 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1566 | 252 | 16441 | 1675 |
TXN,EPHA4,ARFGEF1,LMCD1,NRG2,NDRG2,PSME1,IL18,NENF,PJA2,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,CALM2,ARHGEF10L,DAPK2,SIPA1L2,SESN3,PSMD1,CTGF,NPNT,SHC3,ARHGEF37,IL6ST,RGS3,TSPAN6,IL31RA,DLG1,AKR1B1,DUSP10,RCAN3,TIAM1,S100A13,RASGRP1,CYP1B1,TRIM8,TNIP1,ITCH,PBK,EZR,ARHGDIB,ICMT,PRKRA,SESN1,CDK1,RHEB,ABR,ARHGEF26,OPTN,PLEKHG6,PLCG1,ARHGEF19,GPRC5B,HPSE,DNM1L,ANKRD6,PLK2,MADD,FAM110C,NOD2,PRKCDBP,ADIPOR1,ARF6,UNC5B,HSPB1,RAP1GAP,TRAF5,F2RL1,GAB1,FGD1,RRAGD,PRKAA2,ARAP3,BMF,SERPINE2,NUAK1,RASA2,SOX9,CALM3,PHLPP1,FBLN1,TNFRSF19,IL18R1,KIAA1161,MECOM,ITGA3,RALGPS2,IGF1R,CYR61,PIK3AP1,FAM13B,MAP3K9,SORL1,MDFIC,MYDGF,NCAM1,ALS2CL,MDFI,CALM1,SPATA13,PDE5A,STRADB,PSMA4,C3orf58,RANBP9,G2E3,RASA1,CDK5R1,FAS,GNAS,MAPKAPK2,SEMA4D,PELI2,CSF1,NFKBIA,ITPR1,SH3BP4,FAM83D,FGD6,RHOBTB2,GDF11,MAP3K5,JAK3,XDH,ARHGAP11A,SPRED1,AVPI1,NF2,NLRX1,FOXM1,TRIP10,IL15,PSME2,RALBP1,TP53,ERBB2,BCL2L1,BCAP31,ARHGEF16,EPS8L2,PDGFA,NOV,ST5,DACT1,KIF14,BCL6,DAB2IP,TWIST1,PDE4D,RASGEF1A,CDKN2D,F2R,DVL2,FRS3,CHP1,CTH,MAP3K3,SIRT1,PPIF,TIMP2,RIPK2,AKT1,FIGNL1,FZD4,S100A4,PRKCQ,ERBB2IP,DUSP4,CD40,DAG1,MAP3K6,FZD7,ARHGAP35,IRS2,PTPRJ,JAK1,AXL,STK38,WFS1,SECTM1,SIPA1L1,PLEKHG1,INPP4B,TLE1,SPTBN5,NRG1,RGS14,ABCA1,ARFGEF3,ARHGEF3,PINK1,NKX3-1,ADGRG1,ARHGEF11,PSMD10,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,ARHGEF40,AIP,FGF19,CARD8,ADORA1,PTEN,BMP7,BAX,PLEKHF1,TMBIM6,SLC44A2,BUB1,MAPK11,ERBB3,IQGAP3,SYK,TRIM62,SPRY2,MYO5A,FARP2,HES1,RASGRF1,ARAP2,ARHGEF28,RHOA,PSMB4,RAPGEF2,PLAUR,RC3H2,GRIN1,LITAF,FBXO9,STMN3,MAPK8IP1,ARHGAP24,BANK1,FGFR2,RYK,ARRB1,UACA,GRIN2D,GPER1,LRRK1,FZD5,NDFIP1,L1CAM,ARHGEF9,HIPK3,ARHGEF4 |
| 1.829e-14 | -31.63 | membrane-bounded vesicle | cellular component | GO:0031988 | 3503 | 475 | 17570 | 1756 |
SUN1,LAMP1,GAA,TXN,KLK10,HSPG2,IL15RA,ATP8A1,DNAJC3,HEXB,FBXO2,TGOLN2,PSME1,IL18,LYNX1,NANS,PLXNA1,SYTL4,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,AP1M2,MUC4,ALDH1A3,STEAP2,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,PACSIN1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,MCFD2,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,DNM1L,PTER,ATP7B,BMP1,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,MARCH8,GNS,DOPEY2,ITGA3,SNX18,ZNRF2,MEGF8,ATP5H,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,CADPS2,MYDGF,NCAM1,SYTL3,RIMS2,GPR161,GFPT1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,VEZT,NPC2,ATP8B3,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FAS,PTPRF,AP1AR,SCARB2,NCOA3,SLC4A4,ITPR1,MDH1,KLK7,MAL2,ARPC2,CFAP20,SERPINB1,TMEM173,RUSC1,EHD1,PLA2G4A,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,FTH1,KCTD12,BCL2L1,CD274,MVB12B,PRKACA,DDR1,APPBP2,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,ACSL4,EPHB4,TSPAN1,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,SEC23A,COL6A2,FZD4,SEPT6,SYNE2,CYS1,UTRN,ATP1B1,RAB38,ALCAM,H2AFV,SNX12,GABARAPL1,EPHA10,ALDH3B1,STK26,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,PKN1,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,PDIA4,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,SGK3,CD9,BAX,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,PVRL4,PDGFC,ALDH2,SHMT1,B3GNT2,PLSCR1,RAPGEF2,GRIN1,FURIN,PARP4,C1GALT1C1,AK4,BLVRA,YES1,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,FGFR2,RAB11FIP2,SYT7,DBI,ABCB1,ERAP1,ITGAV,GPER1,FZD5,ARSB,OCLN,CYBRD1,ACOT7,RGMA,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,NDRG2,F11R,MPP5,PDGFB,SDC1,ERP29,SH3KBP1,SUSD2,EPCAM,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,ABCA2,DLG1,AKR1B1,RAB20,RP2,MYH14,CTTN,MYRIP,NEB,S100A13,SMAGP,LAMP3,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,OPTN,DPYSL3,TRIM9,ZNF114,GPRC5B,KCNK1,UEVLD,WIPI1,RAB11FIP1,CAB39,ARRDC1,PIK3C2B,GLA,NRGN,MYL12B,CAPN1,CPPED1,PCSK5,GRN,PRSS8,LASP1,PIFO,FAM213B,BMF,SERPINE2,LGALS3,HLA-F,FXYD3,CALM3,ASAH1,PM20D2,RAB6A,NCKAP1,FBLN1,ANO1,CA2,RINL,COL6A1,AHCY,HLA-C,WNT3A,GAD1,SLC12A2,ALDH3A2,CCDC88A,CKAP4,SNX7,ABCC1,C9orf9,KDELR1,PCBP3,VWA1,SCRIB,NUBP1,C3orf58,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,TMEM30A,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,PROM2,UGP2,PSME2,CTDSPL,HDAC11,COL18A1,MRAS,PHLDA1,BCAP31,SYTL2,PDGFA,ATP6V0B,EFR3A,PLCG2,N4BP3,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,DVL2,CTH,CHP1,CPD,GCA,CLCN3,TIMP2,FIGNL1,S100A4,ACO1,GLO1,IGSF8,CD40,MYL12A,DAG1,ATP13A2,ATP1A1,PTPRJ,BHLHB9,SECTM1,SPTBN5,ANXA9,SYT13,ST3GAL1,LTA4H,ABCA1,LIFR,ARFGEF3,MAN2B2,ANXA3,SORT1,PACSIN2,GOLIM4,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FZD6,TMEM63A,KIF5B,TAF1B,MLPH,CDK16,A4GALT,BMP7,GALNS,FAM63A,ALDH7A1,SYK,ATP2B1,MYO5A,FAH,PGM1,SYPL1,RAB3B,RHOA,FBLN5,PSMB4,IFITM3,GUSB,CRB3,PLAUR,SYBU,COL7A1,GGH,FNDC3A,RNPEP,SCRN2,PRDX4,ENDOD1,FUCA1,CTSL,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,SCG2,DHRS2,PRCP,CTSV,RAP2C,TMC5,PGRMC1,ARRB1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 1.884e-14 | -31.60 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 188 | 56 | 17758 | 1761 |
GCLM,UGT8,ARHGEF3,CEP70,EPAS1,NUAK1,GALNT12,CAST,ITGA6,XYLT1,GNE,ETV5,NDC80,MORC4,HERC5,KCTD12,NTAN1,PLS3,ALPP,GATA2,KCNN4,OPN3,MTMR11,ACSL4,PDE4D,SCARA3,GM2A,SMAGP,CYP1B1,NFE2L3,SGCE,PGM1,CAPN6,SEPT6,SYNE2,SAT1,PTGER4,NPC2,DUSP4,CRISPLD2,OPTN,SCG2,ANKRD6,PTER,NMI,SLC2A6,NR4A3,ERAP1,DHTKD1,CLMN,CDK18,SERPINI1,MAP3K5,FZD5,PER3,L1CAM |
| 2.115e-14 | -31.49 | CAGGTG_V$E12_Q6 | MSigDB lists | CAGGTG_V$E12_Q6 | 2354 | 341 | 17758 | 1761 |
TSC22D3,FBXO2,CACNA2D2,NRG2,PSME1,CAMK1D,LTBP3,SLC9A7,EPDR1,CALM2,CDKN2C,TYMP,CYP1A1,SESN3,AP1M2,RGS3,PAQR5,FOSB,SERINC2,SNX16,PIK3CD,ARMCX6,TIAM1,SMARCA2,FBXL16,SERTAD4,TMEM151A,TFAP2C,TNS1,KIF13A,GALNT7,F12,PPP1R14C,SLC25A5,COL12A1,ABR,RBM47,ATP7B,LRIG1,SERPINI1,UNC5B,ITPKA,ARF6,F2RL1,SCN5A,FRMD4A,CDKN1C,ITGA6,HPCAL4,PSIP1,ITGA3,PIK3AP1,SLC16A6,MEGF8,BHLHE41,DAPK1,TNFRSF12A,CACNA1D,NCAM1,MYLIP,DGKG,RIMS2,IGSF3,SOCS5,EPB41L5,CALM1,PIP4K2C,EPHA1,SPTLC2,GNA11,MMP15,PRKAG2,ETS2,NR4A2,CDK18,MAP3K5,DRP2,HOOK1,EGLN1,EHD1,SPRED1,ARMCX3,GRHL2,TRIP10,THRA,CD82,IQGAP1,CAST,DDIT4L,RNF182,PRSS22,IL13RA1,BCL2L1,PRKACA,DDR1,TMPRSS4,ZNF385B,ZFYVE9,CDS1,NOV,RNF220,SCNN1A,CDH1,ENPP5,RTKN2,ACSL4,SNX10,ETV4,SULT2B1,SEMA3B,SSH3,FZD4,FOXJ2,SYNE2,KIF1C,PRKCQ,ATP1B1,ITPR3,ALCAM,NFIX,ALDH3B1,PDLIM3,CORO1C,AXL,NRG1,NR3C2,COBL,PRR15,MAPK12,IER5L,CTHRC1,NKX3-1,IGFBP6,SDC4,EPS8,ARL4C,PKN1,SEPP1,LGALS3BP,WWP2,CTNNBIP1,AKIRIN1,ADD3,ITGB8,RNF128,SLC27A6,ARSG,FUT8,CD9,TAGLN2,ERBB3,CNOT6L,CITED2,SPRY2,PVRL4,ARAP2,LONRF3,TACC1,BCL9,PIK3R1,ELOVL3,GRIN1,C1GALT1C1,LRRC1,FOS,ACADSB,PLOD2,SYT7,AMMECR1,NR4A3,CCDC69,HMGA1,FZD5,OSR1,OCLN,DEF6,TLL2,RGMA,EXPH5,EMX1,LTBP1,SIGIRR,BCAM,EPAS1,PPM1J,CAMKK1,MGAT5B,ITPR2,SDC1,PDGFB,SPTB,EPCAM,NPNT,ELF5,SLC44A1,DLG1,ABCA2,NTN4,MYH14,BTBD3,NEB,CYP1B1,ZNF462,PCGF5,TRIM8,CELSR2,CBX6,ROR1,ZBTB7B,DPYSL3,MDK,PLEKHG6,GPRC5B,KCNK1,MADD,ARRDC1,SP6,LEMD1,EPB41L4A,NRGN,RRAGD,BMF,SERPINE2,ZNF395,CHCHD7,UBASH3B,CALM3,FAM81A,DHRS3,IGF1R,GATA2,KIF13B,SELK,WNT3A,GAD1,PLCB2,MPHOSPH9,DPYSL5,PCDH1,ELK3,CORO2A,OXR1,MGAT4B,GYLTL1B,VWA1,TCF7,PDIK1L,RANBP9,RASGRP2,EPN3,GNAS,COQ10A,PVRL2,COL13A1,UTP14C,MFSD2A,ITGA7,DONSON,LTBP2,SHROOM2,SEMA3A,RARG,NCKAP5,SORBS1,HOXB7,XYLT1,COL18A1,TDRKH,CYP26A1,PDGFA,ATP6V0B,ARTN,PLK4,BCL6,CDH3,VAT1,EPB41L4B,EGLN3,FRS3,SIRT1,GCA,IGSF8,DUSP4,DOCK5,SOCS3,ATP13A2,DUOX1,PTPRJ,IDE,RBL1,OVOL1,TLE1,SPTBN5,ANXA9,AIFM3,CMTM4,FBLIM1,COL9A3,MACC1,KLHL13,GABRG2,SELL,CRABP2,TRIB2,LBR,SIRPA,NRP2,HDAC9,CCDC92,KIF5B,IRF2BPL,MDM1,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,UBE2J1,TFAP2A,ARVCF,TSPAN13,NR3C1,CRB3,NR4A1,PPARA,PELI3,FNDC3A,TXNDC11,MAPK8IP1,CD83,ARHGAP24,SWAP70,SMTNL2,SCG2,SPINT2,NETO2,UACA,SH3BGRL2,CEP41,AHR,PKIA |
| 2.136e-14 | -31.48 | GGGCGGR_V$SP1_Q6 | MSigDB lists | GGGCGGR_V$SP1_Q6 | 2787 | 391 | 17758 | 1761 |
PPP4R4,TXN,ADD1,TSC22D3,SLC25A13,NRG2,MORF4L2,OAT,DPP8,CENPN,SLC9A7,CALM2,CDKN2C,DAPK2,WEE1,PQLC2,PSMD1,SESN3,ELMO2,STIM1,PRICKLE3,ZFP36,OSBPL3,FOSB,FUT1,KCNS3,ATRNL1,CLDN4,CRY2,IQCD,TINAGL1,XKR8,LAMP2,SMARCA2,SNTB2,TFAP2C,ZFAND5,SLC25A5,RNF19B,COL12A1,ABR,PIAS3,DNM1L,PTER,PLK2,FAM114A1,HDAC1,AGFG2,MRPS28,SERPINI1,UNC5B,HSPB1,HOXC13,NXT2,FGD1,CDK17,GGA1,ITGA6,SOX9,HPCAL4,PSIP1,RABGGTA,TFAP4,ITGA3,LYPD3,BHLHE41,BDH1,FAM13B,RANBP1,RUNDC3B,TNFRSF12A,CACNA1D,NCAM1,ZMYM1,PIKFYVE,MYLIP,C9orf72,EPB41L5,DDB2,CALM1,NPC2,ATP8B3,ELK1,TP53INP2,SPTLC2,NFIB,PSMA4,RASA1,GABRD,TMEM54,AGBL5,FBXO27,PER3,RUSC1,ARMCX3,CEP70,GRHL2,REPS2,TRIP10,THRA,IQGAP1,RGS20,IL13RA1,BCL2L1,GRK6,PRKACA,REPS1,APPBP2,APLP2,ACAP2,RNF220,SH3BP1,XYLT2,CDKN1B,RASGEF1A,DLG3,ETV4,GPX4,SEMA3B,DOCK4,FZD4,DRAP1,KIF1C,SLC11A2,NUSAP1,RAD17,ATP1B1,ALCAM,H2AFV,SP4,FZD7,GABARAPL1,IRS2,PPP2R5A,DDOST,CORO1C,AXL,SLC9A6,SLC27A1,KLF5,HS3ST3B1,PRIMA1,SLC27A3,NR3C2,IER5L,PCOLCE,DCAF7,HABP4,PDIA3,NUCB2,GSTP1,TIPRL,FGF19,EFNB1,SIX4,TEAD3,AKIRIN1,ITGB8,RNF128,FUT8,SGK3,CD9,WWP1,TAGLN2,ERBB3,CITED2,CNPY3,TRIM62,TPCN1,NCOA2,CRTAP,ACBD5,ADAMTS2,SHMT1,ALDH2,LONRF3,NUB1,UBE2A,C1GALT1C1,CNTNAP1,PITX2,TIMP3,RPL12,ACADSB,AMMECR1,NR4A3,HMGA1,ETAA1,FZD5,OSR1,MELK,DEF6,TLL2,EXPH5,CCNI,SIGIRR,CPT2,FLYWCH2,CAMKK1,ARFGEF1,NDRG2,MPP5,TEX2,MGAT5B,TP53I11,ITPR2,HDAC6,SDC1,PDGFB,SPTB,TSEN34,SH3KBP1,CHPF,PLS3,ZFYVE16,NKAIN3,SUSD2,DPYSL2,SIVA1,IL6ST,PHTF1,MITF,PASK,ABCA2,TRPC1,MYH14,BTBD3,PLK1,ATL1,CD55,TRIM8,CITED4,NFE2L1,CBX6,RGAG1,PRKRA,ANLN,IDH1,SESN1,CDK1,OPTN,KDM4D,MAN2A2,ARHGEF19,AGPAT2,WIPI1,HOXA9,ZNF367,KLF11,GLA,NRGN,MAFF,PCSK5,STARD3NL,RMND5A,LASP1,LRRFIP2,ZCCHC24,DNAJB2,ETV5,CALM3,RAB6A,PHLPP1,DAZAP1,IGF1R,KCNN4,TBCD,AHCY,SELK,MDFIC,PIM1,SLC12A2,GAD1,CCDC88A,CYP26B1,MRPS33,ELK3,OXR1,MGAT4B,GYLTL1B,PDE5A,HMG20B,TCF7,EIF2AK1,SCRIB,PDIK1L,C3orf58,CDK5R1,RASGRP2,FOXD2,XKRX,ONECUT1,PVRL2,H1F0,PRPS2,NFKBIA,SLC2A6,ZDHHC7,RARG,KLF7,UPF3B,UGP2,NF2,HOXB7,TP53,TDRKH,BCAP31,IER3,ATP6V0B,ZNF687,ARTN,WDR44,LMO4,REEP1,SRR,PLK4,BCL6,CDH3,GLB1L2,LMAN1,PDIA6,SCYL3,DVL2,FRS3,CPD,SUSD3,MAP3K3,SERTAD3,GLO1,CD40,MAP3K6,ATP13A2,DUOX1,C19orf66,OVOL1,EFNA5,C1orf43,REEP4,ABCA1,COL9A3,PACSIN2,ENO2,CPEB4,CIT,BLVRB,COL4A5,NOTUM,TRIB2,AIP,SIRPA,NRP2,TOP2A,IRF2BPL,MDM1,MLPH,LLGL2,CDK16,BMP7,TOX2,RRBP1,GALNS,SGK1,ARVCF,ABCD1,ALDH7A1,TSPAN13,C12orf75,B3GALT6,SUN2,RHOA,CRB3,DEPDC4,NR4A1,PPARA,OGDHL,STMN3,PRICKLE1,COL7A1,PELI3,LEPR,SWAP70,HNRNPH2,PRCP,RAP2C,PGRMC1,FAM117A,PPP2R3C,CEP41,NDFIP1,AHR,DIS3L |
| 2.424e-14 | -31.35 | MEK_UP.V1_UP | MSigDB lists | MEK_UP.V1_UP | 189 | 56 | 17758 | 1761 |
BCAM,ENO2,EPAS1,GALNT12,GNE,ETV5,ARL4C,EFHD2,GDF15,TP53I11,C11orf95,TMPRSS4,PARM1,TNS3,CYP1A1,KCNN4,BMP7,ALDH1A3,OPN3,MAP3K9,SORL1,CLDN4,LIMCH1,CADPS2,EGLN3,PTPRE,SLC12A2,ULBP2,S100A6,MYO5A,CYP1B1,GCNT1,FADS2,SGCE,TIMP2,PCDH1,PTPRU,PTGER4,VWA1,ARHGDIB,EPHA1,NPC2,DUSP4,SPTLC2,POR,SLC6A6,PTK7,SLC9A6,SLC2A6,ARRB1,CLMN,FHL1,F2RL1,L1CAM,PKIA,ABCG1 |
| 2.831e-14 | -31.20 | single-organism developmental process | biological process | GO:0044767 | 5226 | 671 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,CACNA2D2,NRG2,IL18,GRM5,CDKN2C,CALM2,WEE1,PSMD1,PAQR5,ALDH1A3,KLF3,CLDN4,PIK3CD,SEMA3G,TIAM1,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,HDAC1,TMOD2,ITPKA,ARF6,GAB1,E2F8,HOXC13,SCN5A,ALDH6A1,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,PAQR7,REC8,SALL4,ERO1A,NPHP3,ELK1,TP53INP2,PSMA4,GNA11,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,ITPR1,CLMN,AURKA,GDF11,CFAP20,NDE1,DRP2,ARPC2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,NQO1,INPP5D,C5orf30,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,RAB38,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,WFS1,AXL,CORO1C,SIPA1L1,PNPLA6,TRABD2A,RGS14,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,DCAF7,SDC4,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,SGPL1,NEO1,CTNNBIP1,IGSF9,ITGB8,CTSC,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,SGCB,S100A6,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,CRISPLD2,CNTNAP1,PITX2,ACVRL1,DBI,NR4A3,CENPE,HMGA1,ITGAV,FHL1,OSR1,USF2,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,DZIP1L,DPYSL3,HS6ST1,MAP2,HOXA9,MAFF,MYL12B,RUNX2,LGALS3,RASA2,CNTNAP2,NCKAP1,FBLN1,DHRS3,IL18R1,ANO1,TNS3,DAZAP1,IGF1R,GATA2,FRAS1,KIF13B,PIM1,WNT3A,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,G2E3,PRX,CDK5R1,FOXD2,MAPKAPK2,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,TMEM120A,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,ERBB2,STIL,EMP2,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,DUOX1,IDE,PTPRJ,PTK7,EFNA5,LTA4H,BIN1,COL9A3,PACSIN2,CDH22,CD63,ADGRG1,GABRG2,PSMD10,GDF15,CRABP2,FZD6,PPP2R3A,NRP2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,SYK,TLE6,GCNT1,HES1,RHOA,PSMB4,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,FAT4,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,LGR4,SSH1,HSPG2,VANGL1,TMEM41B,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,TACSTD2,ZBTB18,PACSIN1,SGCE,ACVR1C,CASP9,LDB2,SAV1,CCNF,ZFAND5,ARHGEF26,HLF,PTER,PLK2,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,UNC5B,TANC2,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,CDKN1C,SLC25A27,SLC1A3,HERC6,TNFRSF19,KIAA1161,MECOM,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,EPB41L5,MMD,CALM1,ANO6,AMER1,VEZT,EPHA1,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,MATN2,FAM83D,PCDH19,SFMBT1,NR4A2,HOOK1,EHD1,SPRED1,FOXO6,SLC2A4,TCTN2,ST14,THRA,IQGAP1,RPS6KA1,CAST,BCL2L1,DDR1,MNS1,NOV,APLP2,DOK4,CNNM4,CDKN1B,DAB2IP,EPHB4,PDE4D,MED30,SEMA3B,GPX4,FOXJ2,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,CEP162,EPHA10,JAK1,NGFRAP1,NRG1,KLF5,PRR15,CBX7,COBL,WASF3,PCOLCE,HAPLN3,CENPI,PBX3,SEPP1,SPR,EFNB1,FGF19,ADGRB2,SIX4,TEAD3,E2F7,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,TAGLN2,CITED2,SPRY2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,WDR62,NCAPG2,ARSB,SLC25A38,MELK,JARID2,RGMA,EXPH5,EMX1,CASP3,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,GRHL1,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,RP2,CTTN,MYH14,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,TRIM8,ARHGDIB,EDNRA,MDK,CXXC4,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,CA2,COL6A1,SUCO,C10orf54,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,BCAR3,GNAS,FECH,ONECUT1,TMEM30A,UTP14C,PLPP3,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,APOL2,RARG,KLF7,IL15,PSME2,HDAC11,COL18A1,TDRKH,MRAS,OSR2,PHLDA1,SS18,SETDB2,ARTN,FRYL,KIF14,RPN2,DIXDC1,TWIST1,ECE1,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,PTBP3,TLE1,OVOL1,SPTBN5,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,CIT,FRMD6,LRP4,COL4A5,AES,TGFBR1,HDAC9,TOP2A,KIF5B,MDM1,ADRBK1,ADORA1,LLGL2,MYCL,BMP7,TOX2,RRBP1,KIAA0319,ARVCF,MYO5A,CFAP46,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FOXL1,LEPR,ARHGAP24,SWAP70,PRCP,DHRS2,CTSV,RAP2C,SPINT2,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,L1CAM,AHR |
| 3.704e-14 | -30.93 | KOBAYASHI_EGFR_SIGNALING_24HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_DN | 242 | 65 | 17758 | 1761 |
CCNE2,SPC25,DLGAP5,NDC80,CCNB1,SLC20A1,BARD1,PHLDA1,STIL,CENPN,CARD10,FANCI,IER3,CCND1,KIF14,PLK4,TUBG1,ACOX2,MYBL1,CKS2,PLK1,PPIF,CENPA,PBK,CDC20,NUSAP1,PKMYT1,DUSP4,CCNF,CDK1,PRIM1,AXL,NRG1,MAFF,E2F8,HJURP,DEPDC1,ENO2,ITGA6,ETV5,SOX9,CDCA8,KIF23,GPSM2,TOP2A,FAM111A,RANBP1,NEK2,BUB1,TNFRSF12A,HMMR,ZWINT,ASPM,MYBL2,KIF11,STEAP1,SLCO4A1,FAM64A,NETO2,AURKA,DONSON,UBE2C,NCAPG2,ESPL1,MELK |
| 4.259e-14 | -30.79 | GOLDRATH_ANTIGEN_RESPONSE | MSigDB lists | GOLDRATH_ANTIGEN_RESPONSE | 334 | 80 | 17758 | 1761 |
CASP3,TXN,TTC39B,DLGAP5,S100A11,GNPDA1,CCNB1,IER3,CDKN2C,WEE1,SP100,UBE2T,SIVA1,PLCG2,PLK4,TMEM37,F2R,SNX10,S100A13,CKS2,PLK1,CENPA,FIGNL1,S100A4,SH3BGRL,CDC20,PTGER4,NUSAP1,CCNF,ANLN,DOCK5,H2AFV,ALCAM,CDK1,PRIM1,CARHSP1,SERPINB6,RELL1,E2F8,CD99,RUNX2,LGALS3,CKAP2,CDCA8,EFHD2,IL18R1,HLA-A,LMNA,TOP2A,CA2,CST3,AIM1,NEK2,MDFIC,BUB1,PIM1,IQGAP3,CITED2,SGCB,S100A6,WBP5,SYPL1,PLSCR1,PQLC3,KIF20A,IFITM3,ASPM,LITAF,GGH,KIF11,PRDX4,GALNT3,H1F0,TMEM30A,CDCA5,DBI,AURKA,GEM,CCNB2,ACOT7 |
| 5.200e-14 | -30.59 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14745 | 1564 | 17775 | 1757 |
HECA,AK7,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,GTF2A2,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,MORF4L2,SYTL4,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,MYL9,SIGIRR,TRIM2,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,NKRF,DSE,SLC9A2,PPP2R3A,SIRPA,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,PRDX4,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,RBM47,PLK2,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,ABCD4,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,GAS2L1,SLC25A24,SPC25,FAM92A1,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,SORT1,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.518e-14 | -30.36 | HELLER_HDAC_TARGETS_UP | MSigDB lists | HELLER_HDAC_TARGETS_UP | 299 | 74 | 17758 | 1761 |
SORBS1,DLGAP5,EPAS1,AASS,IL13RA1,APLP2,CYP1A1,LRRC6,BCL6,IFIT1,PIK3CD,CTTN,CDKN2D,GM2A,LAMP3,CPD,ING1,S100A4,CDC20,SAT1,PTGER4,PRKAR2B,CCNF,H2AFV,POR,ATP13A2,HPSE,ANKRD6,PLK2,SERPINI1,NRGN,GRN,CDKN1C,CHCHD7,ITGA6,ZCCHC24,SDC4,BLVRB,GPSM2,SBF1,SEPP1,H1FX,BMP2K,SCML1,SNTA1,TOP2A,GNS,RNF128,LLGL2,SGK3,CD9,RUNDC3B,ADAM15,TSPAN13,NCAM1,NCOA2,HES1,CXorf57,HMG20B,MAPK8IP1,GLCE,MAPKAPK2,NCOA3,TIMP3,H1F0,DHRS2,ITGA7,CGREF1,NR4A2,FHL1,CENPE,L1CAM,IFI6,DOCK9 |
| 7.270e-14 | -30.25 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 15563 | 1630 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,ACOT7,TLL2,CCNI,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,ABCB1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,ARF6,GAB1,E2F8,HOXC13,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,NEK2,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,AHRR,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,STX3,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.033e-13 | -29.90 | BLALOCK_ALZHEIMERS_DISEASE_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_UP | 1631 | 252 | 17758 | 1761 |
EXPH5,LAMP1,CCNI,CASP3,BCAM,SSH1,CPT2,PPFIBP2,TAP1,FBXO2,IL18,NENF,PDGFB,TRIM68,CMTM6,LTBP3,ABCD4,DAPK2,CDKN2C,TYMP,BTG3,METTL7A,STIM1,TSPAN6,ZFP36,IL6ST,MITF,ABCA2,SNX16,RP2,MTMR11,MYBL1,TRAM1,TIPARP,TNIP1,CASP9,NFE2L1,SLC35C1,SAV1,CYP4F3,RHEB,EDNRA,DPYSL3,MAN2A2,NEIL1,KCNMB4,GPRC5B,AGPAT2,AGFG2,HDAC1,PIK3C2B,MAFF,PCSK5,RRAGD,MRC2,RUNX2,LRRFIP2,CDKN1C,GGA1,HLA-E,ITGA6,DNAJB2,SOX9,ASB9,PDCL,ASAH1,C3orf18,FBLN1,BMP2K,LMNA,TNS3,DAZAP1,IGF1R,RPL39,KIF13B,AIM1,PIM1,NCAM1,ETV7,DGKG,ALDH3A2,RIMS2,CKAP4,TRAK2,REC8,ZNF84,ADCK3,MICB,HMG20B,TCF7,SCRIB,ELK1,SPTLC2,NFIB,GLCE,SOX13,RASGRP2,MAPKAPK2,PTPRF,NCOA3,SLC4A4,CSF1,ITGA7,KBTBD2,NFKBIA,MATN2,DONSON,LTBP2,NDE1,PLIN3,JAK3,APOL2,KLF7,EHD1,GAS2L1,SORBS1,NQO1,IL15,S100A11,TRIP10,IQGAP1,CAST,RPS6KA1,ACTR8,THRA,RALBP1,CTDSPL,TP53,COL18A1,IL13RA1,FTH1,MRAS,GRK6,DDR1,CYP39A1,ARHGEF16,ST5,ACAP2,FAM46A,SP100,KIF14,PLCG2,BCL6,VAT1,PDE4D,ECE1,PHKA2,F2R,CTDSP2,NAGA,SEMA3B,SEPHS1,MAP3K3,SSH3,MBP,COL6A2,COG2,S100A4,SEPT6,FOXJ2,SERTAD3,HTATIP2,ERBB2IP,C15orf39,H2AFV,FANCE,CASP4,DAG1,ATP10D,SOCS3,IRS2,TAPBP,PDLIM3,RBL1,WFS1,SECTM1,PNPLA6,TRIOBP,KLF5,IRF7,LIFR,ABCA1,MAPK12,BIN1,PACSIN2,GOLIM4,DCAF7,LRP4,EPS8,OSGIN2,SELL,HERC5,COL4A5,HMGN3,DSE,PKN1,SEPP1,LGALS3BP,SLC9A2,HMGXB4,H1FX,NRP2,PDIA4,SGPL1,WWP2,SNTA1,KIF5B,MDM1,ADD3,ITGB8,FUT2,LLGL2,CALD1,RRBP1,TFAP2A,ATP8B1,TMBIM6,SGK1,KLF9,NPTXR,CNPY3,CLIP2,RBMS2,MED22,AMOTL2,NFE2L3,SUN2,HES1,TGIF1,ARAP2,TACC1,GUSB,GCLC,RC3H2,LITAF,DIAPH2,FBXO9,COL7A1,LRRC1,YES1,PLOD2,PRCP,NR4A3,RYK,CCDC69,ERAP1,GEM,PLOD3,ZMIZ1,UBE2C,USF2,GOLGB1 |
| 1.144e-13 | -29.80 | HALLMARK_ESTROGEN_RESPONSE_LATE | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_LATE | 201 | 57 | 17758 | 1761 |
KLK10,PAPSS2,ST14,BLVRB,RET,CACNA2D2,COX6C,EMP2,STIL,IL17RB,CCND1,TOP2A,BTG3,ADD3,SCNN1A,RPS6KA2,CA2,CDH1,LLGL2,CYP4F11,ZFP36,IL6ST,OPN3,CD9,PLK4,SGK1,FAM102A,TSPAN13,ACOX2,SULT2B1,SNX10,TIAM1,ALDH3A2,SEMA3B,CYP26B1,PPIF,KIF20A,CELSR2,PRSS23,MICB,AMFR,CDC20,TFAP2C,PRKAR2B,FOS,MDK,ALDH3B1,JAK1,SERPINA1,PDLIM3,TJP3,DHRS2,WFS1,ANXA9,GLA,PTGES,TOB1 |
| 1.272e-13 | -29.69 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 690 | 131 | 17758 | 1761 |
CCNI,HECA,SSH1,TSC22D3,CUL4B,RET,TAP1,IL18,MPP5,F11R,ITPR2,MORF4L2,SIPA1L2,STIM1,METTL7A,DPYSL2,PIK3CA,TMEM143,DUSP10,SNX16,CTTN,PTPRE,DDX59,CD55,TRIM8,NFE2L1,IDH1,PLCH1,CARHSP1,MID1IP1,PTER,RAB11FIP1,SERPINB6,MAFF,CDK17,ALDH6A1,HLA-E,ZCCHC24,HLA-F,ETV5,B4GALT4,IL18R1,TTYH3,PSIP1,BMP2K,GNS,SLC16A6,C10orf54,NCEH1,C9orf9,GFPT1,DDB2,IFIT3,NPHP3,NCOA3,ITPR1,STK39,NDE1,SERPINB1,RNF146,EHD1,SLC25A24,NQO1,ARMCX3,S100A11,CAST,FTH1,TMEM170B,PHLDA1,RCN1,SP100,LMO4,BCL6,TWIST1,PDE4D,SCYL3,CTH,TIMP2,FOXJ2,UTRN,CD40,DUSP4,MYL12A,DNAJC10,JAK1,CDK19,C19orf66,TRIOBP,RGS14,ST3GAL1,ANXA3,CPEB4,GNE,BLVRB,MIER3,TGFBR1,TRIB2,ETS1,ARHGEF40,H1FX,DNAJB9,HLA-A,SLC25A36,HDAC9,IRF2BPL,CCDC92,E2F7,FAM111A,TMEM87B,GNB5,LLGL2,FAM63A,KLF9,SGCB,SYK,MYO5A,TGIF1,ARAP2,PLSCR1,NR3C1,RAPGEF2,SNTB1,BSDC1,KLHL2,ERAP1,CCDC69,PPP2R3C,ITGAV,CPEB2,ARHGEF9,GOLGB1 |
| 1.324e-13 | -29.65 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16676 | 1712 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.347e-13 | -29.64 | MODULE_6 | MSigDB lists | MODULE_6 | 399 | 89 | 17758 | 1761 |
MYL9,LTBP1,TRIM2,NQO1,HSPG2,EPAS1,S100A11,CRYM,SDC1,DDR1,ARHGEF16,CHPF,IER3,CCND1,EPCAM,CYP1A1,ST5,SCNN1A,CDH1,LMO4,ALDH1A3,FOSB,BCL6,CLDN4,TACSTD2,NOTCH3,LGMN,TSPAN1,CYP1B1,CPD,SGCE,CD55,COL6A2,PTPRU,S100A4,ITPR3,ALCAM,DPYSL3,MDK,ALDH3B1,HLF,AGPAT2,BMP1,KLF5,MAFF,GRN,PRSS8,COL9A3,PCOLCE,IGFBP6,ATP9A,ITGA6,SOX9,GNE,ASAH1,GDF15,NUCB2,SEPP1,DHRS3,FBLN1,S100A2,HOXB2,ELF3,TMEM63A,M6PR,CYR61,CTSC,LLGL2,KCNN4,COL6A1,IGFBP2,ERBB3,CITED2,SLC12A2,HES1,PRSS23,NR4A1,GCLC,FOS,CYB5A,FUCA1,TIMP3,SERPINA1,ETS2,ITGA7,DTX4,STK39,GEM,SERPINB1 |
| 1.383e-13 | -29.61 | regulation of molecular function | biological process | GO:0065009 | 2753 | 391 | 16441 | 1675 |
TXN,PPP4R4,ADD1,DNAJC3,RET,NRG2,PSME1,CAMK1D,CCNB1,CARD10,GRM5,CALM2,CDKN2C,PSMD1,CTGF,STIM1,CABP1,RGS3,SERINC2,PIK3CA,CRY2,RCAN3,TIAM1,ACVR1C,CASP9,PRKAR2B,PIF1,SAV1,PPP1R14C,POR,ARF4,ARHGEF26,ABR,PLCG1,MID1IP1,PLK2,LIMK1,NOD2,AGFG2,SERPINB6,SERPINI1,HSPB1,TRAF5,GAB1,FGD1,DDX58,CDKN1C,TBC1D1,NUAK1,ITGA6,GPSM2,BMP2K,TFAP4,RALGPS2,CYR61,SNX18,PPP4R1,FAM13B,RANBP1,NEK2,DAPK1,MAP3K9,PRKG1,SORL1,CACNA1D,NCAM1,PPP6R1,GPR161,SOCS5,EPB41L5,MMD,TBC1D8B,CALM1,EPHA1,PSMA4,NFIB,PLIN5,RASA1,FAS,MMP15,PTPRF,NCOA3,PRKAG2,SEMA4D,ITPR1,FGD6,AURKA,NR4A2,STK39,CABIN1,MAP3K5,SERPINB1,TMEM173,XDH,EGLN1,DOCK9,ARHGAP11A,SPRED1,GRHL2,NQO1,THRA,RPS6KA1,RALBP1,CAST,IQGAP1,PTTG1,RGS20,MGST2,PRKACA,EPS8L2,CCND1,APLP2,ST5,ACAP2,SP100,SH3BP1,CDKN1B,DAB2IP,PDE4D,IFIT1,DLG3,RASGEF1A,CDKN2D,DOCK4,CAMSAP3,RIPK2,FZD4,UTRN,PRKCQ,SLC11A2,ATP1B1,PKMYT1,ITPR3,GTF2A2,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,SIPA1L1,PLEKHG1,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,TCAF1,CTHRC1,ARHGEF3,PCOLCE,NKX3-1,DEPDC1,SDC4,HABP4,HERC5,ANO9,PKN1,SPR,GSTP1,ARHGEF40,TIPRL,FGF19,WWP2,CTNNBIP1,DIRAS3,GNB5,CTSC,PTEN,CST3,SGK3,BAX,ADAM15,TMBIM6,MAPK11,ERBB3,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,RAPGEF2,PIK3R1,GRIN1,FURIN,GRTP1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,GRIN2D,GPER1,CENPE,FHL1,FZD5,CPEB2,SIGIRR,CASP3,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,DENND2D,SPTB,ARHGEF10L,SIPA1L2,NPNT,SHC3,ARHGEF37,SIVA1,DLG1,DUSP10,RP2,SLC39A10,RASGRP1,CYP1B1,ZNF462,PLK1,TRIM8,ITCH,ARHGDIB,PRKRA,CDK1,EDNRA,KDM4D,PLEKHG6,NEIL1,ARHGEF19,GPRC5B,MADD,CAB39,GLA,RAP1GAP,PIFO,LMTK3,ARAP3,PPP1R2,HJURP,SERPINE2,BVES,RASA2,UBASH3B,FXYD3,CALM3,FBLN1,IGF1R,RINL,TBCD,FXYD5,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,CCDC88A,MDFI,SPATA13,STRADB,PDE5A,SCRIB,CDK5R1,RASGRP2,GNAS,MAPKAPK2,BCAR3,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,CTSA,ATP1B3,JAK3,IFI6,PROM2,CCNE2,AVPI1,NF2,PSME2,TP53,ERBB2,EMP2,STIL,BCAP31,ARHGEF16,SYTL2,PDGFA,KIF14,PLCG2,BCL6,CDH3,TWIST1,OAS3,TMEM64,EGLN3,F2R,GM2A,DVL2,FRS3,CTH,CKS2,CHP1,MAP3K3,PPIF,SIRT1,TIMP2,AKT1,CDC20,ERBB2IP,DUSP4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,DNAJC10,PTPRJ,RBL1,STK38,MMP17,SPTBN5,EFNA5,PPP2R2D,ARFGEF3,ANXA3,GCLM,PINK1,SORT1,ARHGEF11,DAP,PSMD10,TGFBR1,AES,TRIB2,SBF1,AIP,PARM1,PPP2R3A,FZD6,SH2D4A,ZDHHC21,CD109,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,SGK1,TRIM21,BUB1,IQGAP3,SYK,MYO5A,HES1,RHOA,PSMB4,PLAUR,AMFR,PPARA,RGCC,STMN3,COL7A1,LEPR,MAPK8IP1,ARHGAP24,SERPINA1,SPINT2,RAP2C,NETO2,ARRB1,PPP2R3C,NDFIP1,TBC1D4,UBE2C,ARHGEF9,HIPK3,PKIA,RAB3IL1,ARHGEF4 |
| 1.486e-13 | -29.54 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | 542 | 110 | 17758 | 1761 |
ARHGAP11A,CCNE2,CASP3,SPC25,CEP70,DLGAP5,FOXM1,PTTG1,NDC80,NUF2,SLC7A2,CCNB1,FAM101B,STIL,MNS1,CENPN,FANCI,CDKN2C,WEE1,UBE2T,SIVA1,OSBPL3,PASK,PLK4,HYLS1,RNF26,MYBL1,SEPHS1,CKS2,PLK1,PPIF,CENPA,FIGNL1,PBK,S100A4,SERTAD4,CDC20,PLEKHO1,NUSAP1,CDCA2,PIF1,PKMYT1,CCNF,DOCK5,STK17B,CDK1,PRIM1,JAK1,MAP2,ANKRD6,RBL1,LIMK1,ZNF367,ZNF704,FAM195A,ISOC1,IER5L,LASP1,HJURP,DEPDC1,SERPINE2,CKAP2,POC1B,DCAF7,CENPI,CIT,BLVRB,CDCA8,ERI2,KIF23,SLC1A3,TSPAN7,H1FX,TOP2A,FAM111A,E2F7,IGF1R,NEK2,BUB1,LIMCH1,ERBB3,IQGAP3,NUP85,SNX7,HMMR,DLGAP1,CYP26B1,SHMT1,KIF20A,ASPM,RC3H2,MYBL2,CCDC34,NEURL1B,BORA,KIF11,NFIB,FAM64A,CDCA5,CDCA7L,FAM83D,AURKA,ETAA1,CENPE,WDR62,NCAPG2,UBE2C,CCNB2,ESPL1,MELK |
| 1.573e-13 | -29.48 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 267 | 68 | 17758 | 1761 |
ARMCX3,ST14,NRG2,SDC1,PHLDA1,FAM46C,EPDR1,EPCAM,RGS3,IL6ST,RAB20,MANF,LMAN1,PDIA6,MCFD2,C15orf39,IRS2,AMZ2,ENPP1,RBM47,WIPI1,NGFRAP1,SHROOM3,ANKRD6,WFS1,TANC2,ABCA1,DENND5B,TSPAN15,PDIA3,CTSZ,NCKAP1,SLC1A3,RABGGTA,PDIA4,FOXP2,B3GALNT1,IGF1R,KCNN4,SLC16A6,RRBP1,UBE2J1,TPST1,PLEKHF1,ECI2,ALDH7A1,TSPAN13,CITED2,CKAP4,KDELR1,FARP2,ABCC1,FADS2,IFITM3,GUSB,OXR1,GYLTL1B,PRICKLE1,FNDC3A,BBS2,TXNDC11,ANTXR1,SPINT2,MATN2,UACA,CDK18,SH3BGRL2,TMEM173 |
| 1.619e-13 | -29.45 | rectum | COSMIC cancer mutations | rectum | 16679 | 1712 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.961e-13 | -29.26 | positive regulation of cellular process | biological process | GO:0048522 | 4598 | 598 | 16441 | 1675 |
ACACB,DNAJC3,HEXB,RET,NRG2,IL18,MORF4L2,SYTL4,BARD1,CARD10,LTBP3,GRM5,CALM2,DAPK2,PSMD1,ALDH1A3,SEMA3G,PIK3CD,TIAM1,SMARCA2,TNIP1,SH3BGRL,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,ABR,PIAS3,PGF,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,E2F8,GAB1,HOXC13,SCN5A,ITGA6,SOX9,MERTK,LMNA,ELF3,TFAP4,MEGF8,FLRT3,NEK2,MAP3K9,MYDGF,NCAM1,NUP85,SALL4,STAT4,PYM1,MYBL2,ELK1,TP53INP2,PSMA4,PLIN5,STK17A,NCOA3,ETS2,SEMA4D,SETD3,AURKA,STK39,GDF11,ARPC2,CFAP20,TMEM173,RUSC1,XDH,GRHL2,NQO1,INPP5D,MVB12B,PRKACA,TNFSF9,CCND1,ST5,RNF220,CDH1,SP100,DACT1,RTKN2,ACSL4,RAB27B,RASGEF1A,ETV4,RIPK2,FZD4,SYNE2,CDCA2,NUSAP1,GTF2A2,NFIX,IRS2,CDK19,WFS1,CORO1C,AXL,RGS14,MAPK12,CTHRC1,TCAF1,TNRC6C,NKX3-1,CKAP2,SDC4,PDIA3,PKN1,ETS1,GSTP1,SRPX2,NEO1,CTNNBIP1,CXCL16,CTSC,FAM20B,CST3,BAX,PLEKHF1,IGFBP2,MAPK11,S100A6,PLSCR1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,CNTNAP1,PITX2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,HMGA1,CENPE,OSR1,USF2,ILDR1,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,LMCD1,NENF,HDAC6,PDGFB,SDC1,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,ELF5,PASK,MITF,MYBL1,S100A13,ZNF462,PLK1,THRB,PCGF5,CD55,CITED4,NFE2L1,EZR,KLK6,PRKRA,CDK1,RHEB,OPTN,DPYSL3,KDM4D,AGPAT2,KLF12,PRKCDBP,KLF11,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,DNAJB2,RASA2,NCKAP1,FBLN1,IL18R1,ANO1,TNS3,DAZAP1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,RGMB,STRADB,SCRIB,CDK5R1,MAPKAPK2,PVRL2,CSF1,NLRC5,ATP1B3,SEMA3A,RNF146,AVPI1,NF2,UPF3B,FOXM1,TP53,ERBB2,LPIN3,EMP2,STIL,BCAP31,RAD23A,PDGFA,LMO4,PLCG2,BCL6,PLK4,CDH3,ESPN,NOTCH3,TMEM64,LMAN1,EGLN3,DVL2,CTH,SULF2,SIRT1,PPIF,CLCN3,TIMP2,AKT1,S100A4,CDC20,SERTAD3,PTGER4,DAG1,PTPRJ,IDE,RBL1,PTK7,EFNA5,IRF7,BIN1,PINK1,MACC1,CD63,ADGRG1,DAP,SELL,PSMD10,GDF15,HMGN3,CRABP2,PARM1,NRP2,PPP2R3A,GTF2F2,TFAP2A,TRIM21,BUB1,SYK,TLE6,NFE2L3,HES1,RHOA,PSMB4,NR3C1,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,BCAR1,MAPK8IP1,CD83,BANK1,TWSG1,SCG2,CDCA7L,NMI,PPP2R3C,ICOSLG,NDFIP1,UBE2C,ARHGEF9,ARHGEF4,LAMP1,TXN,LGR4,ATP8A1,PSME1,CAMK1D,CCNB1,SLC20A1,NCS1,CYP1A1,CTGF,STIM1,ZFP36,FOSB,IL31RA,PIK3CA,IRF2,TACSTD2,PACSIN1,ACVR1C,CASP9,NBPF3,SAV1,LDB2,SLC25A5,POR,AHRR,PLK2,NKD1,FAM110C,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,SCOC,CDKN1C,HLA-E,SLC25A27,KIF23,SLC1A3,TNFRSF19,PSIP1,KIAA1161,MECOM,C9orf69,ITGA3,CYR61,PIK3AP1,DAPK1,SORL1,TNFRSF12A,GPR161,RIMS2,SOCS5,EPB41L5,KLK5,MFI2,MMD,CALM1,ANO6,AMER1,PIP4K2C,EPHA1,NFIB,RASA1,STX3,FAS,PRKAG2,PELI2,FAM83D,NR4A2,MAP3K5,EHD1,SPRED1,FOXO6,DLGAP5,ARMCX3,THRA,IQGAP1,RPS6KA1,CD274,BCL2L1,AIFM2,MNS1,EPS8L2,NOV,CDKN1B,DAB2IP,IFIT1,PDE4D,TSPAN1,MED30,NR2C1,SEMA3B,DOCK4,FOXJ2,UTRN,PRKCQ,SLC11A2,PYGO1,ATP1B1,ITPR3,FZD7,PPP2R5A,JAK1,STK26,NGFRAP1,TRIOBP,SLC27A1,NRG1,KLF5,COBL,WASF3,ARHGEF3,PCOLCE,EPS8,PBX3,EFNB1,FGF19,TEAD3,HLA-A,ADGRB2,SIX4,WWP2,E2F7,RNF128,PTEN,SLC44A2,ERBB3,CNOT6L,CITED2,TRIM62,SPRY2,OSGIN1,NCOA2,PDGFC,TGIF1,RASGRF1,FURIN,YES1,FOS,GPLD1,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,ARSB,ESPL1,MELK,JARID2,RGMA,EXPH5,CASP3,CAMKK1,ERP29,EPCAM,RAB15,HSF2,GRHL1,TSPAN6,DPYSL2,SIVA1,DLG1,AKR1B1,TRPC1,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,TRIM8,STK17B,EDNRA,MDK,GPRC5B,HPSE,MADD,CAB39,SP6,ADIPOR1,RAP1GAP,CAPN1,NR2C2,GRN,PIFO,LASP1,SERPINE2,BVES,ETV5,CALM3,TEC,ADAMTSL4,CA2,KCNN4,SUCO,C10orf54,ZRANB1,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,GNAS,BCAR3,ONECUT1,NUDT16,PLPP3,TMEM30A,NFKBIA,CDCA5,SH3BP4,EGFL7,JAK3,RARG,COL16A1,TOB1,PROM2,KLF7,SORBS1,IL15,PSME2,COL18A1,OSR2,PHLDA1,ARHGEF16,SS18,KIF14,TWIST1,DIXDC1,ECE1,EPB41L4B,F2R,FRS3,CHP1,MAP3K3,CD40,DOCK5,MAP3K6,SOCS3,ARHGAP35,JADE1,BHLHB9,SECTM1,OVOL1,SPTBN5,LIFR,ABCA1,GLIS3,ANXA3,ARHGEF11,TSPAN15,CIT,LRP4,AES,TGFBR1,TRIB2,HDAC9,IRF2BPL,TOP2A,KIF5B,CARD8,ADRBK1,ADORA1,BMP7,TOX2,IQGAP3,SUN2,RAB3B,NR4A1,GCLC,ASPM,RC3H2,RGCC,RUNX3,SWAP70,RAP2C,ARRB1,ZMIZ1,SOX8,L1CAM,AHR |
| 2.155e-13 | -29.17 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 531 | 108 | 17758 | 1761 |
MYL9,LMO7,CCNE2,CCDC109B,TXN,ADD1,XYLT1,EPHA4,NUF2,FAM198B,SNN,FAM46C,CARD10,SYTL2,APOBEC3B,SIPA1L2,METTL7A,OSBPL3,ALDH1A3,TWIST1,NTN4,SCARA3,ANO4,SMAGP,GPX4,TMEM200B,TMTC1,COL6A2,TIMP2,SNTB2,S100A4,UTRN,LOXL2,ROR1,TP53I3,ZNF469,OPTN,PRIM1,DPYSL3,NFIX,MDK,CARHSP1,GPRC5B,ABHD12,AXL,CORO1C,PRKCDBP,HSPB1,F2RL1,NR3C2,CD99,CTHRC1,PCOLCE,IGFBP6,ITGA6,BLVRB,SDC4,ARL4C,DHRS3,TNFRSF19,FBLN1,ANO1,LMNA,MECOM,DTX3L,TNS3,FRY,RNF128,COL6A1,CD9,OPN3,ATP8B1,C10orf54,C12orf75,S100A6,PARP9,SNX7,FAM69A,NFE2L3,ADAMTS2,RAB3B,PRSS23,PQLC3,RGMB,IFITM3,PRICKLE1,STMN3,PDE5A,KIF11,FOXL1,CYB5A,STK17A,CNTNAP1,PRKAG2,NMI,MATN2,SH3BP4,FGD6,ARRB1,UACA,LTBP2,HMGA1,PLIN3,SHROOM2,MELK,ACOT7,KLF7,EHD1 |
| 2.290e-13 | -29.11 | LIU_PROSTATE_CANCER_DN | MSigDB lists | LIU_PROSTATE_CANCER_DN | 456 | 97 | 17758 | 1761 |
MYL9,LTBP1,ACACB,SORBS1,FAM92A1,HSPG2,EPAS1,TSC22D3,FHDC1,FBXO2,MRAS,OSR2,SDC1,PHLDA1,BTG3,ZNF75D,ST5,GRHL1,METTL7A,DOK4,AKR1B1,DAB2IP,NTN4,ACOX2,TMEM200B,SGCE,TIMP2,CELSR2,SPATA18,SH3BGRL,S100A4,CYS1,TNS1,FZD7,OPTN,DPYSL3,PGF,DUOX1,HLF,WFS1,CORO1C,TSPAN18,KLF11,PRIMA1,UNC5B,HSPB1,TRAF5,NR3C2,MRC2,ENO2,TBC1D1,HLA-E,FRMD6,TGFBR1,ISYNA1,CRABP2,DSE,GSTP1,ARHGEF40,ANO1,RAVER2,MECOM,CALD1,FLRT3,COL6A1,TPST1,NCAM1,C12orf75,ALDH3A2,S100A6,GPR161,SNX7,PDGFC,DDB2,ALDH2,FBLN5,MFI2,PRSS23,LONRF3,TACC1,PIK3R1,COL7A1,NEURL1B,CRISPLD2,CACHD1,SLC6A6,TIMP3,PLEKHH2,ETS2,FGFR2,COL13A1,MFSD2A,FAM83D,CLIP4,FHL1,PER3,COL16A1 |
| 2.455e-13 | -29.04 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 443 | 95 | 17758 | 1761 |
FAM92A1,IL15,RALBP1,CUL4B,PTTG1,NDC80,RGS20,KCTD12,RNF182,FAM101B,PHLDA1,STIL,SH3KBP1,CDKN2C,PDGFA,CPNE2,PSMD1,AKR1B1,PIK3CD,PLK1,TIMP2,COL6A2,CDC20,LOXL2,MCFD2,ANLN,ATP10D,FZD7,CMTM7,SOCS3,GPRC5B,POPDC3,CORO1C,AXL,PRKCDBP,BIN1,CD99,GLIS3,FBLIM1,RUNX2,MRC2,ARAP3,HJURP,IGFBP6,DEPDC1,SERPINE2,TBC1D1,UBASH3B,ZCCHC24,ETV5,DSE,S100A2,ETS1,ARHGEF40,GSTP1,ADD3,CTSC,CALD1,PPP4R1,COL6A1,TOX2,FXYD5,SGK1,CCDC82,BUB1,MDFIC,PIM1,CLIP2,SGCB,SPRY2,GPR161,CCDC88A,CRTAP,FAM69A,WBP5,SNX7,CYP26B1,PDGFC,ELK3,NR3C1,MPP1,EIF5A2,STRADB,ANTXR1,FAS,STK17A,FAT4,TWSG1,COL13A1,LTBP2,FHL1,ITGAV,LRRK1,SEMA3A,SERPINB1 |
| 2.521e-13 | -29.01 | single-organism process | biological process | GO:0044699 | 12803 | 1417 | 16441 | 1675 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,TTYH3,RABGGTA,ATG4A,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,MYDGF,PANX2,DGKG,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,ADAMTS16,DOCK9,TPRN,NQO1,INPP5D,CD82,PTTG1,C5orf30,GRK6,MGST2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,RASGEF1A,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,SEPT6,SAT1,HTATIP2,XRCC6BP1,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,MAPK12,CTHRC1,CKAP2,DCAF7,SDC4,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,BAX,KLC3,IGFBP2,PARP9,ACBD5,PVRL4,OPLAH,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,TLL2,CCNI,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,ITPR2,MGAT5B,SPTB,FANCI,PLS3,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,KCNMB4,AGPAT2,HOXA9,KLF11,MYL12B,RRAGD,RUNX2,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,DPYSL5,PCDH1,RGMB,MGAT4B,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,P4HA3,SLC2A6,ZDHHC7,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,ABHD12,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDH22,KLHL13,HAL,CDCA8,GDF15,LBR,AIP,VPS26A,DNAJB9,FZD6,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,HES1,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,CFAP61,SLC35D2,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,STIM1,OSBPL3,KCNS3,SERINC2,PIK3CA,IRF2,SNX16,TACSTD2,ZBTB18,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,GDE1,LRIG1,PRDM5,BMP1,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,THEMIS2,TMEM55B,HERC6,TNFRSF19,S100A2,TSPAN7,MESDC2,C9orf69,DOPEY2,RALGPS2,BHLHE41,RPL39,PPP4R1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,ADCK3,LPGAT1,CALM1,NPC2,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,MATN2,FAM83D,SFMBT1,CABIN1,KLK7,PER3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,ST14,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,PRR15,CBX7,COBL,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,ADGRB2,SLC25A36,RASSF8,E2F7,GNB5,FJX1,FUT8,DRAM1,CD9,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,FBXO9,DIAPH2,YES1,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,HSF2,SIVA1,CEP78,TRPC1,CTTN,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,LIMCH1,HLA-C,C10orf54,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,ELK3,PODXL2,VWA1,PDE5A,NUBP1,C3orf58,MFSD7,RANBP9,STEAP1,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,CCNE2,DYNLRB1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ARTN,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,COL4A5,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,B3GALT6,PGM1,CFAP46,RC3H2,RGCC,NADK2,TTC7A,RUNX3,FOXL1,LEPR,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,NRG2,IL18,MORF4L2,SYTL4,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,ALDH1A3,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,PGF,DNM1L,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,GNS,FAM13B,NEK2,NCAM1,NDUFA12,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,CYB5A,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,NDE1,DRP2,ARPC2,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,ETS1,GSTP1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,SIGIRR,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,SDC1,SHC3,CNTRL,ELF5,DUSP10,ANO4,TLN2,TRAM1,MYBL1,S100A13,NEB,CD55,ING1,MCTP1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,H1F0,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,AVPI1,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,PLCG2,LHX6,SRR,EGLN3,MINPP1,SCN2A,GM2A,DVL2,CTH,SIRT1,TIMP2,EVA1A,MBP,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,MAN2B2,COL9A3,PACSIN2,MFSD14B,CD63,ADGRG1,DAP,GNE,BLVRB,SWI5,PSMD10,SELL,GABRG2,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,ABCD1,FAIM,TLE6,FAH,DLGAP1,HMMR,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,CD83,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,NAT1,TMC5,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,UBE2C,SUN1,GAA,TMEM41B,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,CTGF,ELMO2,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,PACSIN1,RCAN3,XKR8,LAMP2,ORAI2,KIFC2,PBK,CASP9,TNS1,AGO4,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,HLF,SLC25A4,PLK2,GNPTAB,PTER,NKD1,SARAF,DHTKD1,EIF4EBP2,UNC5B,TANC2,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,NDUFA4,SLC1A3,ISYNA1,KIAA1161,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,MMD,MFI2,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,CD274,AIFM2,MNS1,APLP2,DOK4,CNNM4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,H2AFV,NIN,CMTM7,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,LGALS3BP,TEAD3,SIX4,SNTA1,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,PGM2L1,GRIN2D,GPER1,NCAPG2,ARSB,SLC25A38,OCLN,ESYT2,JARID2,EXPH5,EMX1,LTBP1,CASP3,NMRK1,CPT2,CAMKK1,CACNB4,DNER,KREMEN1,TMC1,PTCHD4,SH3KBP1,ABCD4,CHPF,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,DLG1,AKR1B1,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,STRIP2,ROR1,MRPS36,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,UEVLD,ADIPOR1,RAP1GAP,GRN,FAM213B,PIFO,LRRFIP2,PEX6,PHLPP1,CA2,KCNN4,DIAPH2-AS1,FXYD5,NCEH1,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,AMDHD1,GLCE,GNAS,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,PLPP3,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,SLC25A48,SS18,SVBP,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,AES,NOTUM,POMGNT1,SAC3D1,IL17RB,MDM1,ADORA1,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,OGDHL,HLA-B,DHRS2,PRCP,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 2.835e-13 | -28.89 | cellular developmental process | biological process | GO:0048869 | 3526 | 478 | 16441 | 1675 |
ADD1,HSPG2,SSH1,LGR4,AK7,RET,HEXB,CACNA2D2,NRG2,PSME1,PLXNA1,CAMK1D,CCNB1,FAM101B,NCS1,GRM5,CALM2,CDKN2C,WEE1,TYMP,PSMD1,CYP1A1,CTGF,PAQR5,IL31RA,PIK3CD,SEMA3G,PACSIN1,ZBTB18,TIPARP,TIAM1,DNAAF3,SMARCA2,SPEF2,ACVR1C,CASP9,TFAP2C,LOXL2,SAV1,ARF4,ARHGEF26,COL12A1,PGF,PLCG1,HLF,DNM1L,LIMK1,PTER,PLK2,TRAF3IP1,NKD1,BMP1,HDAC1,DHTKD1,TMOD2,UNC5B,ITPKA,ARF6,F2RL1,E2F8,LZTS1,SEMA6B,SCN5A,MRC2,ALDH6A1,CDKN1C,ITGA6,SOX9,MTL5,RAB23,SLC1A3,GPSM2,HERC6,MERTK,KIAA1161,LMNA,ELF3,MECOM,ITGA3,FRY,CYR61,FLRT3,MEGF8,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,PIKFYVE,DGKG,RIMS2,PAQR7,EPB41L5,REC8,MMD,CALM1,ERO1A,AMER1,EPHA1,NPHP3,ELK1,TP53INP2,ANTXR1,NFIB,PSMA4,STX3,RASA1,FAS,PTPRF,MMP15,ETS2,SEMA4D,MATN2,FAM83D,CLMN,AURKA,SFMBT1,NR4A2,GDF11,ARPC2,CFAP20,NDE1,HOOK1,EHD1,MTM1,SPRED1,FOXO6,SLC2A4,GRHL2,TCTN2,ST14,THRA,IQGAP1,CAST,RPS6KA1,C5orf30,BCL2L1,APC2,PRKACA,TNFSF9,CCND1,NOV,CDH1,DACT1,DAB2IP,EPHB4,ACSL4,PDE4D,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,FOXJ2,HTATIP2,SLC11A2,PRKCQ,RAB38,PYGO1,ALCAM,FZD7,CMTM7,NFIX,CEP162,EPHA10,IRS2,JAK1,SHROOM3,SLC9A6,AXL,CORO1C,SIPA1L1,KLF5,NRG1,RGS14,COBL,MAPK12,TTC8,WASF3,CTHRC1,SDC4,PBX3,PLPPR4,SPR,ETS1,EFNB1,FGF19,SIX4,TEAD3,NEO1,SGPL1,E2F7,IGSF9,PTEN,CST3,BAX,CD9,ADAM15,ATP8B1,MAPK11,TAGLN2,ERBB3,CITED2,SGCB,SPRY2,S100A6,OSGIN1,FARP2,RASGRF1,TGIF1,B3GNT2,ARHGEF28,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,FBXO9,C1GALT1C1,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,PITX2,CNTNAP1,ACVRL1,FGFR2,TBX18,NR4A3,RYK,ERAP1,GRIN2D,GPER1,ITGAV,FHL1,LRRK1,FZD5,OSR1,WDR62,ARSB,SLC25A38,JARID2,TLL2,RGMA,EXPH5,MYL9,CASP3,EMX1,UGT8,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,MPP5,DNER,SDC1,PDGFB,CACNB4,SPTB,TMC1,PLS3,EPCAM,RPS6KA2,LRRC6,NPNT,SHC3,DPYSL2,IL6ST,IMPAD1,MITF,ELF5,DLG1,TMEM143,DUSP10,TRPC1,NTN4,RP2,CTTN,MYH14,BTBD3,RASGRP1,THRB,ATL1,CELSR2,NFE2L1,EZR,CR2,KLK6,ANLN,ZBTB7B,CDK1,RHEB,DZIP1L,DPYSL3,EDNRA,MDK,HS6ST1,GPRC5B,MAP2,MYL12B,MAFF,NR2C2,GRN,RUNX2,LGALS3,SERPINE2,BVES,RASA2,ETV5,CALM3,CNTNAP2,TEC,IL18R1,DAZAP1,IGF1R,GATA2,KIF13B,COL6A1,C10orf54,WNT3A,ETV7,CCDC88A,MDFI,CYP26B1,DPYSL5,ELK3,RGMB,STRADB,HMG20B,TCF7,SCRIB,EIF2AK1,RANBP9,CDK5R1,FOXD2,FECH,ONECUT1,PVRL2,COL13A1,UTP14C,MFSD2A,ITGA7,TMEM30A,CSF1,PLPP3,EGFL7,PITPNA,TMEM120A,JAK3,SHROOM2,SEMA3A,RARG,KLF7,HOXB7,NF2,IL15,FOXM1,PSME2,HDAC11,TP53,COL18A1,ERBB2,TDRKH,OSR2,STIL,PHLDA1,TTC21B,PDGFA,SS18,ARTN,KIF14,LMO4,FRYL,LHX6,PLCG2,PLK4,BCL6,CDH3,TWIST1,DIXDC1,NOTCH3,SULF2,FRS3,SIRT1,TIMP2,AKT1,FIGNL1,PTPRU,OSTM1,S100A4,CDC20,PTGER4,GLO1,MYL12A,DAG1,SOCS3,ARHGAP35,PTPRJ,BFSP1,BHLHB9,PTK7,PEX2,PTBP3,EFNA5,SPTBN5,LTA4H,LIFR,BIN1,COL9A3,PACSIN2,SORT1,ARHGEF11,ADGRG1,CD63,POC1B,CIT,FRMD6,LRP4,PSMD10,COL4A5,GDF15,TGFBR1,CRABP2,NRP2,PPP2R3A,HDAC9,TOP2A,CD109,KIF5B,LLGL2,CDK16,MYCL,BMP7,RRBP1,KIAA0319,TFAP2A,UBE2J1,SGK1,SYK,TLE6,MYO5A,HES1,RHOA,PSMB4,CFAP46,ASPM,NR4A1,RC3H2,STMN3,RUNX3,COL7A1,FNDC3A,BBS2,FOXL1,ARHGAP24,FAT4,TWSG1,DHRS2,CTSV,RAP2C,SPINT2,PGRMC1,HOXB13,CEP41,PLOD3,ZMIZ1,SOX8,L1CAM |
| 3.324e-13 | -28.73 | nervous system development | biological process | GO:0007399 | 2292 | 335 | 16441 | 1675 |
HSPG2,SSH1,AK7,TMEM41B,RET,HEXB,NRG2,PSME1,PLXNA1,CAMK1D,NCS1,GRM5,CALM2,CDKN2C,WEE1,PSMD1,ALDH1A3,SEMA3G,PACSIN1,ZBTB18,TIAM1,SMARCA2,SPEF2,TFAP2C,ARF4,ABR,PLCG1,LIMK1,PLK2,TRAF3IP1,NKD1,LRIG1,SERPINI1,TMOD2,UNC5B,ITPKA,ARF6,LZTS1,SEMA6B,SCN5A,CDKN1C,SOX9,RAB23,SLC1A3,HPCAL4,MECOM,ITGA3,FRY,FLRT3,MEGF8,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,PIKFYVE,MYLIP,DGKG,RIMS2,MMD,SALL4,CALM1,EPHA1,NFIB,PSMA4,STX3,RASA1,FAS,PTPRF,TIMM8A,SEMA4D,MATN2,CLMN,PCDH19,AURKA,NR4A2,GDF11,ARPC2,NDE1,DRP2,EHD1,SPRED1,FOXO6,GRHL2,ST14,THRA,IQGAP1,CAST,RPS6KA1,PRKACA,APLP2,CDH1,DACT1,DOK4,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,MYT1,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,EPHA10,IRS2,JAK1,SHROOM3,AXL,SLC9A6,SIPA1L1,NRG1,RGS14,COBL,WASF3,CTHRC1,HAPLN3,SDC4,PBX3,PLPPR4,SPR,SEPP1,GSTP1,ETS1,HOXB2,FGF19,EFNB1,SIX4,ADGRB2,TEAD3,NEO1,IGSF9,PTEN,CST3,CD9,BAX,ATP8B1,WWP1,ERBB3,S100A6,FARP2,RASGRF1,TGIF1,PDGFC,B3GNT2,ARHGEF28,FMN1,TACC1,RAPGEF2,GRIN1,AK4,YES1,FOS,CDK5RAP1,CNTNAP1,PITX2,TIMP3,FGFR2,DBI,NR4A3,RYK,GRIN2D,GPER1,ITGAV,FZD5,WDR62,ARSB,JARID2,RGMA,MYL9,CASP3,EMX1,UGT8,CUL4B,EPHA4,ARFGEF1,NDRG2,MPP5,DNER,PDGFB,CACNB4,TMC1,SPTB,PLS3,RPS6KA2,SHC3,DPYSL2,IL6ST,DLG1,DUSP10,TRPC1,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,CELSR2,EZR,KLK6,CDK1,RHEB,DPYSL3,EDNRA,MDK,HS6ST1,GPRC5B,MAP2,NRGN,MYL12B,NR2C2,GRN,RUNX2,SERPINE2,RASA2,ETV5,CALM3,CNTNAP2,NCKAP1,IGF1R,GATA2,KIF13B,COL6A1,WNT3A,ALDH3A2,CCDC88A,DPYSL5,PCDH1,RGMB,HMG20B,TCF7,SCRIB,RANBP9,PRX,CDK5R1,PHLPP2,CSF1,PLPP3,TMEM30A,PITPNA,SEMA3A,SHROOM2,JAK3,RARG,KLF7,NF2,PSME2,HDAC11,TP53,ERBB2,PHLDA1,STIL,TTC21B,PDGFA,ARTN,KIF14,LMO4,FRYL,LHX6,SRR,BCL6,TWIST1,DIXDC1,NOTCH3,SCN2A,DVL2,SULF2,FRS3,MBP,TIMP2,AKT1,CDC20,IGSF8,MYL12A,DAG1,ARHGAP35,PTPRJ,ALDH5A1,BHLHB9,PTK7,PEX2,SPTBN5,EFNA5,LIFR,BIN1,ANXA3,COL9A3,CDH22,ADGRG1,ARHGEF11,CIT,LRP4,PSMD10,TGFBR1,COL4A5,CRABP2,PPP2R3A,FZD6,NRP2,HDAC9,KIF5B,FOXP2,ADORA1,CDK16,LLGL2,MYCL,BMP7,KIAA0319,TFAP2A,SGK1,TLE6,MYO5A,HES1,RHOA,PSMB4,ASPM,PRICKLE1,STMN3,RUNX3,BBS2,FAT4,TWSG1,SPINT2,CTSV,PGRMC1,SOX8,PLOD3,L1CAM |
| 3.407e-13 | -28.71 | regulation of catalytic activity | biological process | GO:0050790 | 2284 | 334 | 16441 | 1675 |
TXN,PPP4R4,DNAJC3,RET,NRG2,PSME1,CCNB1,CARD10,GRM5,CALM2,CDKN2C,PSMD1,CTGF,CABP1,RGS3,SERINC2,PIK3CA,CRY2,RCAN3,TIAM1,ACVR1C,CASP9,PRKAR2B,PIF1,PPP1R14C,POR,ARF4,ABR,ARHGEF26,PLCG1,MID1IP1,LIMK1,NOD2,AGFG2,SERPINB6,SERPINI1,HSPB1,GAB1,FGD1,CDKN1C,TBC1D1,NUAK1,ITGA6,GPSM2,BMP2K,TFAP4,RALGPS2,CYR61,SNX18,PPP4R1,RANBP1,FAM13B,NEK2,DAPK1,MAP3K9,PRKG1,SORL1,NCAM1,PPP6R1,GPR161,SOCS5,MMD,TBC1D8B,CALM1,EPHA1,PSMA4,PLIN5,RASA1,FAS,MMP15,PRKAG2,SEMA4D,ITPR1,FGD6,NR4A2,STK39,CABIN1,MAP3K5,SERPINB1,XDH,EGLN1,DOCK9,ARHGAP11A,SPRED1,GRHL2,NQO1,RPS6KA1,RALBP1,IQGAP1,CAST,PTTG1,RGS20,MGST2,PRKACA,EPS8L2,CCND1,APLP2,ST5,ACAP2,SH3BP1,CDKN1B,DAB2IP,IFIT1,DLG3,RASGEF1A,CDKN2D,DOCK4,CAMSAP3,RIPK2,FZD4,PRKCQ,SLC11A2,ATP1B1,PKMYT1,ITPR3,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,SIPA1L1,PLEKHG1,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,ARHGEF3,PCOLCE,NKX3-1,DEPDC1,SDC4,HERC5,PKN1,SPR,GSTP1,ARHGEF40,TIPRL,FGF19,DIRAS3,CTSC,PTEN,CST3,BAX,TMBIM6,MAPK11,ERBB3,SPRY2,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,RAPGEF2,PIK3R1,GRIN1,FURIN,GRTP1,GPLD1,CDK5RAP1,TIMP3,FGFR2,GRIN2D,GPER1,CENPE,FZD5,CPEB2,CASP3,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,ERP29,DENND2D,SPTB,ARHGEF10L,SIPA1L2,NPNT,SHC3,ARHGEF37,DLG1,DUSP10,RP2,SLC39A10,RASGRP1,PLK1,ARHGDIB,PRKRA,CDK1,EDNRA,PLEKHG6,NEIL1,ARHGEF19,GPRC5B,MADD,CAB39,GLA,RAP1GAP,PIFO,LMTK3,ARAP3,PPP1R2,SERPINE2,BVES,RASA2,UBASH3B,FXYD3,CALM3,FBLN1,IGF1R,RINL,TBCD,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,CCDC88A,MDFI,SPATA13,STRADB,PDE5A,SCRIB,CDK5R1,RASGRP2,GNAS,BCAR3,MAPKAPK2,CSF1,SH3BP4,NLRC5,CTSA,ATP1B3,JAK3,IFI6,PROM2,CCNE2,AVPI1,NF2,PSME2,TP53,ERBB2,EMP2,STIL,BCAP31,ARHGEF16,SYTL2,PDGFA,KIF14,BCL6,CDH3,OAS3,TMEM64,EGLN3,F2R,GM2A,DVL2,FRS3,CHP1,CKS2,MAP3K3,PPIF,SIRT1,TIMP2,AKT1,CDC20,DUSP4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,DNAJC10,PTPRJ,RBL1,STK38,MMP17,SPTBN5,EFNA5,PPP2R2D,ARFGEF3,GCLM,ANXA3,PINK1,SORT1,ARHGEF11,DAP,PSMD10,TGFBR1,TRIB2,SBF1,AIP,PARM1,PPP2R3A,SH2D4A,ZDHHC21,CD109,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,SGK1,BUB1,IQGAP3,SYK,RHOA,PSMB4,PLAUR,RGCC,STMN3,COL7A1,LEPR,MAPK8IP1,ARHGAP24,SERPINA1,SPINT2,RAP2C,ARRB1,PPP2R3C,UBE2C,TBC1D4,ARHGEF9,HIPK3,PKIA,RAB3IL1,ARHGEF4 |
| 3.698e-13 | -28.63 | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | MSigDB lists | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | 135 | 44 | 17758 | 1761 |
CCNE2,CCDC109B,DLGAP5,HJURP,FOXM1,MRPS15,PTTG1,NDC80,CDCA8,KIF23,CCNB1,STIL,FANCI,SAC3D1,TOP2A,APOBEC3B,CA2,KIF14,NEK2,BUB1,CKS2,HMMR,PLK1,CENPA,ZWINT,KIF20A,ASPM,PBK,CDC20,MYBL2,NUSAP1,GGH,CCNF,KIF11,CDK1,NETO2,AURKA,HMGA1,CENPE,CCNB2,UBE2C,E2F8,ESPL1,MELK |
| 4.429e-13 | -28.45 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 8129 | 946 | 17775 | 1757 |
ACACB,ADD1,IL15RA,AASS,AK7,SLC25A13,DNAJC3,HEXB,RET,CACNA2D2,DHX8,NRG2,IL18,SYTL4,LACTB2,CA8,BARD1,LTBP3,CALM2,CDKN2C,DAPK2,WEE1,AP1M2,KIAA1107,CABP1,CYP2S1,PAQR5,ALDH1A3,KLF3,FUT1,PIK3CD,TIAM1,MGAT5,ERAP2,NWD1,SMARCA2,TNIP1,SH3BGRL,SERTAD4,TMEM151A,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,ABR,ENPP1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,FAM114A1,NOD2,HDAC1,MRPS28,TMOD2,RELL1,ITPKA,HSPB1,GAB1,MTL5,SLC36A4,MERTK,TTYH3,LMNA,RAVER2,ATG4A,MARCH8,GNS,FRY,FAM189A1,RIMS3,NEK2,MAP3K9,CADPS2,ALPK1,NCAM1,NDUFA12,DGKG,NUP85,C9orf72,MCCC2,HPS3,SLC37A1,PQLC3,SALL4,STAT4,MYBL2,ELK1,SPTLC2,SFXN5,GNA11,PSMA4,DCP2,STK17A,DHX32,PTPRF,CACHD1,SCARB2,SLC4A4,SEMA4D,SETD3,S100A5,CLMN,AURKA,GDF11,FBXO27,TMEM159,NDE1,DRP2,ARPC2,XDH,ADAMTS16,EGLN1,DOCK9,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,PTTG1,RGS20,PKP2,TESK2,IL13RA1,GRK6,PRKACA,ZNF385B,APPBP2,CDS1,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,XYLT2,RTKN2,RAB27B,DLG3,SNX10,MYT1,TMEM9,SCN3A,MX1,SEC61B,COL6A2,RIPK2,PTPN9,SEPT6,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,XRCC6BP1,GABARAPL1,IRS2,PDLIM3,SHROOM3,CDK19,CORO1C,AXL,SIPA1L1,INPP4B,PLEKHG1,PRIMA1,MAPK12,TTC8,TNRC6C,HABP4,SDC4,PDIA3,ANO9,PKN1,PLPPR4,SLC25A43,NEO1,PDIA4,ADD3,ITGB8,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,FAM20B,KLC3,FAM102A,ADAM15,WWP1,IGFBP2,MAPK11,SGCB,CRTAP,ACBD5,AMOTL2,PVRL4,ADAMTS2,LCA5,PLSCR1,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,CXorf57,AK4,BLVRA,NEURL1B,SNTB1,CRISPLD2,PLOD2,RAB11FIP2,ACVRL1,SYT7,PPM1H,USF2,DCBLD1,CYBRD1,ACOT7,TLL2,MYL9,KIAA1462,EPAS1,PPM1J,GNPDA1,FAM199X,CNOT8,EPHA4,ARFGEF1,LMCD1,TEX2,F11R,ITPR2,NUP62CL,SDC1,SPTB,PLS3,CPNE2,RPS6KA2,NPNT,SHC3,IL6ST,PAPSS1,SLC44A1,TMEM143,DUSP10,NTN4,ANO4,TLN2,TRAM1,DDX59,NEB,SMAGP,CCDC38,ZNF462,PLK1,THRB,MCTP1,KCNIP3,CELSR2,CBX6,EZR,CR2,KLK6,ANLN,IDH1,RHEB,DZIP1L,OPTN,TRIM9,PLEKHG6,MFAP3L,HS6ST1,KCNMB4,MSL1,AGPAT2,KLF12,MAP2,WIPI1,P4HA2,DOLPP1,ZNF367,KLF11,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MYL12B,RRAGD,RMND5A,PRKAA2,UBASH3B,ADCK5,RAB6A,CNTNAP2,NCKAP1,FBLN1,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,MDFIC,PIM1,FAR2,WNT3A,PLCB2,ALDH3A2,CYP26B1,CHSY3,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,TESK1,ZNF320,STRADB,EIF2AK1,TCF7,PDK3,ANKRD29,G2E3,MAPKAPK2,KBTBD2,PHLPP2,P4HA3,PRPS2,NLRC5,LTBP2,ATP1B3,PLD1,SEMA3A,CCNB2,USP43,NF2,UGP2,FOXM1,CTDSPL,TMX4,XYLT1,TP53,CCDC68,ERBB2,LPIN3,STIL,RAD23A,TTC21B,WDR44,EFR3A,LMO4,PLK4,CDH3,GLB1L2,ESPN,OAS3,MINPP1,SCN2A,LMAN1,CTDSP2,DVL2,CTH,SULF2,CPD,SIRT1,CLCN3,TMTC1,MBP,ERLEC1,AKT1,COQ10B,PTGER4,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,ABHD12,RBL1,PTK7,STK38,ADAMTS14,EFNA5,ANXA9,SYT13,NDST3,CMTM4,BIN1,CMAS,PINK1,GOLIM4,CDH22,CPEB4,RUSC2,DAP,HAL,ERI2,GABRG2,PSMD10,CRABP2,DSE,SLC9A2,PPP2R3A,NRP2,SIRPA,SH2D4A,CD109,C16orf74,CDK16,LYPD6,GTF2F2,SGK1,TSPAN13,BUB1,ALDH7A1,ABCD1,SYK,ATP2B1,FAH,NFE2L3,DLGAP1,FBLN5,MOSPD2,NR3C1,AMFR,MAML2,GGH,COL7A1,PELI3,FNDC3A,BBS2,MAPK8IP1,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,ICOSLG,NDFIP1,TBC1D4,PTGES,HIPK3,ARHGEF4,GOLGB1,LAMP1,GAA,SLC35D2,PPP4R4,LGR4,HSPG2,SSH1,VANGL1,TMEM41B,ATP8A1,PPFIBP2,PLXNA1,NANS,CAMK1D,VASH1,SLC9A7,NCS1,TYMP,SESN3,ANKS6,ZNF823,ELMO2,STIM1,ZFP36,OSBPL3,IQCE,IL31RA,AOX1,PIK3CA,ATRNL1,SNX16,IQCD,LOC81691,SGCE,KIFC2,SPATA18,ACVR1C,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,LDB2,SAV1,CCNF,ZFAND5,SLC25A5,ARHGEF26,AHRR,SLC25A4,PLK2,PTER,GNPTAB,LRIG1,NKD1,PRDM5,SERPINI1,TANC2,UNC5B,F2RL1,FGD1,DDX58,MRC2,CDK17,FRMD4A,TBC1D1,TMEM55B,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,TNFRSF19,S100A2,PSIP1,BMP2K,C9orf69,DOPEY2,RALGPS2,ITGA3,LYPD3,PIK3AP1,ZNRF2,BDH1,RUNDC3B,DAPK1,OPN3,ADCK2,TPST1,PRKG1,TMEM51,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,SYTL3,GPR161,FAM69A,EPB41L5,PMPCB,DDB2,KCNJ12,PRODH,KLK5,MFI2,TBC1D8B,ADCK3,LPGAT1,PIP4K2C,ANTXR1,NFIB,RASA1,STX3,FRMD4B,MMP15,DGKH,AP1AR,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,PELI2,DCK,FAM83D,AGBL5,FGD6,SFMBT1,PCDH19,CABIN1,KLK7,NR4A2,CDK18,MAP3K5,HOOK1,IFIH1,NRBP1,EHD1,FRMPD3,PLA2G4A,SPRED1,TCTN2,DLGAP5,CEP70,IQGAP1,RALBP1,RPS6KA1,THRA,ATP2C2,BCL2L1,TMEM170B,DDR1,AIFM2,TMPRSS4,CYP39A1,ZFYVE9,EPS8L2,APLP2,NOV,ZNF75D,ACAP2,FAM46A,CNNM4,EPHB4,PHKA2,MED30,GPX4,ATG4D,MYO5B,SEC23A,CAPN6,UTRN,KIF1C,PRKCQ,PKMYT1,PYGO1,ATP1B1,ITPR3,ALCAM,H2AFV,ATP10D,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,DDOST,PPP2R5A,JAK1,TSPAN18,ZNF704,SLC27A1,NRG1,MLKL,HS3ST3B1,NR3C2,COBL,CBX7,DENND5B,WASF3,PCOLCE,ATP9A,CENPI,EPS8,CCNJL,HERC5,PBX3,FBXO6,SPR,DNAH3,SIX4,TMCC3,SLC25A36,WWP2,RASSF8,E2F7,FAM111A,TMEM87B,RNF128,PTEN,FUT8,SGK3,CD9,ATP8B1,SLC44A2,ERBB3,SLC16A5,NCOA2,FARP2,TGIF1,PDGFC,ARHGEF28,SHMT1,ARAP2,ERMAP,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,DIAPH2,FBXO9,YES1,LRRC1,GRTP1,KIF11,CDK5RAP1,DCTN6,NUCB1,ACADSB,FGFR2,TBX18,AMMECR1,ABCB1,PGM2L1,ERAP1,GRIN2D,ARSB,CXorf56,MELK,OCLN,DEF6,JARID2,RGMA,ESYT2,EXPH5,LTBP1,UGT8,CRYM,HEBP1,CAMKK1,MPP5,DNER,CACNB4,TMC1,PTCHD4,SH3KBP1,ABCD4,ARHGEF10L,NKAIN3,ZFYVE16,SIPA1L2,LRRC6,ARHGEF37,SIVA1,DPYSL2,IMPAD1,PHTF1,ANKFN1,DLG1,POF1B,TRPC1,AKR1B1,RAB20,SUN3,RP2,MYH14,TECR,SLC39A10,PTPRE,MYRIP,RASGRP1,LAMP3,ATL1,TRIM8,ITCH,RGAG1,ROR1,PTGFRN,STK17B,ADRBK2,EDNRA,CXXC4,MAN2A2,ARHGEF19,HPSE,KCNK1,MADD,ADIPOR1,NRGN,CAPN1,CPPED1,PCSK5,NR2C2,LASP1,ZNF395,LRRFIP2,BVES,ETV5,ABCG2,CALM3,SAMD9,FAM81A,PHLPP1,ADAMTSL4,ZNF432,AIM1L,COL6A1,FXYD5,LIMCH1,ZRANB1,LRIF1,SLC12A2,ETV7,ALS2CL,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,AMDHD1,RANBP9,MUM1L1,SOX13,GNAS,BCAR3,XKRX,FECH,SLC6A6,UAP1,UTP14C,TMEM30A,SH3BP4,ALPK3,PITPNA,SHROOM2,JAK3,COL16A1,APOL2,SNX30,KLF7,CCNE2,LMO7,LZTFL1,DYNLRB1,NCKAP5,FAM92A1,SPC25,PDIA5,COL18A1,IL27RA,MRAS,TDRKH,PHLDA1,KCTD9,LRRC45,SS18,SLC25A48,CYP4F11,ZDHHC12,FRYL,REEP1,RPN2,DIXDC1,EPB41L4B,ECE1,F2R,SCYL3,SEPHS1,MAP3K3,PTPRU,SLC39A8,GLO1,ERBB2IP,DOCK5,MAP3K6,CASP4,ALDH5A1,BFSP1,TLE1,OVOL1,VSIG10,SPTBN5,ABCA1,LNP1,PPP2R2D,LIFR,GLIS3,ANXA3,GCLM,ARHGEF11,TSPAN15,FRMD6,POC1B,LRP4,ARMC7,TGFBR1,COL4A5,TRMT2B,INTS8,TRIB2,TMEM63A,IL17RB,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,GALNS,KIAA0319,IQGAP3,MYO5A,RBMS2,B3GALT6,PGM1,SYPL1,RAB3B,NR4A1,DEPDC4,ASPM,RC3H2,OGDHL,MBNL3,LRRC66,TTC7A,RUNX3,KLHL2,ENDOD1,SWAP70,TRIM69,PRCP,SPINT2,OTUB2,UACA,ARRB1,GRAMD1C,HOXB13,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1 |
| 4.638e-13 | -28.40 | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | 310 | 74 | 17758 | 1761 |
DLGAP5,PTTG1,MORC4,TESK2,ERBB2,BCL2L1,CCNB1,MNS1,CENPN,APOBEC3B,CDKN2C,BTG3,KIF14,PLK4,ACSL4,CKS2,CPD,PLK1,GCA,LOC81691,ING1,C6orf1,CENPA,FIGNL1,SLC39A8,PANK1,SLC11A2,GLO1,PPP1R14C,H2AFV,CDK1,ARHGEF26,RBL1,E2F8,NXT2,DEPDC1,CKAP2,BLVRB,CDCA8,OSGIN2,KIF23,NUCB2,SAC3D1,SCML1,IL17RB,SNTA1,TOP2A,PIK3AP1,NEK2,DAPK1,BUB1,NCEH1,C12orf75,SHMT1,ZWINT,SPATA13,MYBL2,GGH,KIF11,PRDX4,BCAR3,TWSG1,ITPR1,DBI,PRPS2,NETO2,FAM83D,AURKA,CSTF2,CENPE,NCAPG2,UBE2C,CCNB2,MELK |
| 4.761e-13 | -28.37 | GNF2_CDC2 | MSigDB lists | GNF2_CDC2 | 61 | 28 | 17758 | 1761 |
HMMR,ZWINT,KIF20A,DLGAP5,HJURP,FOXM1,CKAP2,ASPM,CDC20,PTTG1,NDC80,MYBL2,CDCA8,NUSAP1,CCNF,KIF11,CDK1,FANCI,PRIM1,TOP2A,PLK4,AURKA,CENPE,UBE2C,CCNB2,E2F8,MELK,CKS2 |
| 5.139e-13 | -28.30 | intracellular | cellular component | GO:0005622 | 13688 | 1482 | 17570 | 1756 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CARD10,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,MYDGF,PANX2,ZMYM1,DGKG,MYLIP,NUP85,PPP6R1,MCCC2,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,PLIN5,ETS2,S100A5,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,DOCK9,NQO1,INPP5D,PTTG1,C5orf30,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,DCAF7,ESRP1,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,OPLAH,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,ILDR1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,CPNE2,BTG3,RPS6KA2,NPNT,PAPSS1,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,METAP2,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,GDE1,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,TNFRSF19,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,SLC8B1,TRIM68,ZFYVE16,RAB15,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PDE5A,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,SEPHS1,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,ARHGEF11,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,NRG2,DHX8,IL18,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,ALDH1A3,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,FBXO27,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,SSH3,CAMSAP3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,TMA16,NUCB2,ETS1,ARHGEF40,GSTP1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,ADD3,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,UNKL,MYL9,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,ANO4,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,EPN3,COQ10A,H1F0,ITGA7,CSF1,MFSD2A,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,LHX6,PLCG2,N4BP3,SRR,SCN2A,MINPP1,EGLN3,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,EVA1A,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,BLVRB,GNE,SWI5,PSMD10,NKRF,CRABP2,DSE,PPP2R3A,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,PRDX4,FUCA1,SERPINA1,FAT4,ZNF214,NAT1,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IL31RA,STEAP2,AOX1,PACSIN1,RCAN3,LAMP2,LOC81691,KIFC2,SNTB2,PBK,CASP9,NBPF3,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,NKD1,FAM110C,SARAF,DHTKD1,EIF4EBP2,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,BDH1,SORL1,PIKFYVE,RIMS2,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,MMD,ZNF84,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,PRKAG2,DCK,CSNK1G1,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,CEP70,ARMCX3,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,RNF182,SNN,AIFM2,MNS1,APLP2,ZNF75D,DOK4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,NIN,PRDM11,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,CSTF2,PGM2L1,GRIN2D,GPER1,ETAA1,ARSB,NCAPG2,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,TSEN34,SH3KBP1,ABCD4,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,EDNRA,CXXC4,MDK,NEIL1,ZNF114,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,RFX5,NCEH1,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,HMG20B,AMDHD1,GLCE,GNAS,FECH,BCAR3,NUDT16,ONECUT1,PLPP3,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,GCA,ZNF525,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,ARMC7,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,IL17RB,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,DHRS2,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 5.317e-13 | -28.26 | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | MSigDB lists | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | 435 | 93 | 17758 | 1761 |
CCNE2,UGT8,SPC25,DLGAP5,FOXM1,VANGL1,PTTG1,NDC80,RGS20,PKP2,CCNB1,CENPN,FANCI,CALM2,APOBEC3B,CDKN2C,SS18,MUC16,ARTN,IMPAD1,KIF14,PLK4,TUBG1,EGLN3,ARL4D,MYBL1,CDKN2D,SEPHS1,CKS2,PPIF,SEC23A,CENPA,RIPK2,PBK,ITCH,CDC20,NUSAP1,F12,CDK1,PRIM1,CARHSP1,ENPP1,DNM1L,RBL1,E2F8,PRKAA2,CMAS,HJURP,DEPDC1,CKAP2,CENPI,CDCA8,KIF23,CALM3,GPSM2,SLC9A2,TOP2A,NEK2,CD70,BUB1,LRIF1,MPHOSPH9,ATP2B1,SNX7,HMMR,ZWINT,KIF20A,ASPM,CALM1,RC3H2,MYBL2,AK4,GGH,KIF11,CDK5R1,GNAS,FAM64A,TWSG1,PLOD2,TIMM8A,DCK,NETO2,AURKA,PPP2R3C,HMGA1,CENPE,WDR62,NCAPG2,UBE2C,SEMA3A,CCNB2,ACOT7,MELK |
| 5.905e-13 | -28.16 | CHICAS_RB1_TARGETS_SENESCENT | MSigDB lists | CHICAS_RB1_TARGETS_SENESCENT | 539 | 108 | 17758 | 1761 |
CCNE2,CCDC109B,PSME2,CD82,KCTD12,IL27RA,CD274,SLC7A2,VASH1,FAM101B,EMP2,SLC20A1,PHLDA1,FANCI,WEE1,CPNE2,APLP2,BTG3,SP100,UBE2T,IL6ST,PAQR5,ALDH1A3,TUBG1,TRPC1,LRP11,RAB27B,APOBEC3G,ERAP2,CTH,COL6A2,RIPK2,SPATA18,SLC39A8,CYB5R2,NUSAP1,RAB38,ATP1B1,LDB2,PRIM1,EDNRA,DPYSL3,PDLIM3,HPSE,ZNF367,FAM114A1,LRIG1,NRG1,NFKBIZ,GLCCI1,SLC27A3,ST3GAL1,NRGN,GLIS3,GCLM,PCOLCE,FRMD4A,ENO2,NUCB2,TRIB2,PSIP1,LGALS3BP,SAC3D1,SLC25A36,DIRAS3,DTX3L,ADD3,MLPH,SPIN4,FUT8,RANBP1,ALDH7A1,NUP85,FAH,SNX7,CYP26B1,TGIF1,DDB2,MMD,PLSCR1,GUSB,OXR1,BTN3A2,STMN3,COL7A1,IFIT3,BBS2,STEAP1,CYB5A,HLA-B,SLCO4A1,SERPINA1,TMEM54,DCK,CDCA7L,PRPS2,NETO2,DONSON,GEM,NDE1,NCAPG2,IFI6,DCBLD1,MELK,ACOT7,TMEM173,CYBRD1,JARID2 |
| 6.131e-13 | -28.12 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 363 | 82 | 17758 | 1761 |
SPRED1,IL15RA,LGR4,TP53,IL13RA1,OSR2,CA8,MNS1,CENPN,SP100,NPNT,LMO4,ALDH1A3,CTTN,TSPAN1,CD55,FIGNL1,SH3BGRL,ITCH,SYNE2,C3orf52,EZR,LOXL2,H2AFV,ZFAND5,PRIM1,ALDH5A1,ABHD12,P4HA2,LRIG1,ZNF165,ANXA9,GLCCI1,E2F8,PRR15,GLIS3,FXYD3,ABCG2,HMGN3,B4GALT4,S100A2,PSIP1,PPP2R3A,PARM1,H1FX,HLA-A,RASSF8,E2F7,ADD3,ITGA3,SLC16A6,BMP7,DRAM1,FXYD5,CACNA1D,SYK,C9orf72,MCCC2,RAB3B,ASPM,MICB,PLAUR,PIK3R1,CCDC34,EPHA1,AIF1L,KIF11,STEAP1,LEPR,KLHL2,BCAR3,HLA-B,TJP3,ETS2,PLOD2,COL13A1,TMEM30A,RAP2C,ARRB1,PTGES,PKIA,EHD1 |
| 6.759e-13 | -28.02 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 1013 | 175 | 16441 | 1675 |
MYL9,LTBP1,CASP3,RET,EPHA4,NRG2,F11R,PSME1,ITPR2,PDGFB,SPTB,SH3KBP1,CALM2,ZFYVE16,RPS6KA2,PSMD1,CTGF,ELMO2,SHC3,ZCCHC12,IL6ST,IL31RA,PIK3CA,PIK3CD,MYH14,TIAM1,PTPRE,TIPARP,RASGRP1,ACVR1C,CASP9,PRKAR2B,AGO4,ROR1,ZFAND5,ARF4,ABR,RHEB,PGF,PLCG1,LIMK1,CAB39,HDAC1,EIF4EBP2,HSPB1,GAB1,MYL12B,RRAGD,PCSK5,FGD1,PRKAA2,RUNX2,RASA2,SOX9,CALM3,TEC,NCKAP1,PHLPP1,IGF1R,MEGF8,FLRT3,C10orf54,NCAM1,SOCS5,RGMB,CALM1,STRADB,EPHA1,ELK1,PSMA4,RASA1,CDK5R1,PTPRF,MAPKAPK2,PRKAG2,PHLPP2,CSF1,NFKBIA,ITPR1,LTBP2,GDF11,ARPC2,JAK3,TOB1,SPRED1,SORBS1,REPS2,IQGAP1,PSME2,RPS6KA1,TP53,ERBB2,PRKACA,DDR1,ARHGEF16,ZFYVE9,PDGFA,ATP6V0B,SS18,DOK4,CDKN1B,DAB2IP,EPHB4,RASGEF1A,FRS3,SULF2,AKT1,RIPK2,PTPRU,ERBB2IP,ITPR3,DUSP4,MYL12A,SOCS3,EPHA10,IRS2,PTPRJ,IDE,JAK1,RBL1,NGFRAP1,AXL,SLC9A6,SIPA1L1,SPTBN5,NRG1,EFNA5,RGS14,LIFR,MAPK12,SORT1,TNRC6C,ARHGEF3,ARHGEF11,LRP4,EPS8,PSMD10,GDF15,TGFBR1,FGF19,EFNB1,NRP2,SGPL1,ADRBK1,PTEN,BMP7,FUT8,MAPK11,ERBB3,CITED2,SPRY2,SYK,RASGRF1,TGIF1,PDGFC,ARHGEF28,RHOA,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,BCAR1,GPLD1,TWSG1,FGFR2,ACVRL1,GRIN2D,ITGAV,ARHGEF9,ARHGEF4,RGMA |
| 6.768e-13 | -28.02 | intracellular part | cellular component | GO:0044424 | 13357 | 1452 | 17570 | 1756 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CARD10,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,COX6C,FAM21C,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,PANX2,ZMYM1,DGKG,MYLIP,NUP85,PPP6R1,MCCC2,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,PLIN5,ETS2,S100A5,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,DOCK9,NQO1,INPP5D,PTTG1,C5orf30,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,DCAF7,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,OPLAH,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,ILDR1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,CPNE2,BTG3,RPS6KA2,NPNT,PAPSS1,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,METAP2,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,GDE1,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,RAD17,PYGO1,PKMYT1,ITPR3,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,SLC8B1,TRIM68,ZFYVE16,RAB15,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PDE5A,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,AFAP1,SNX30,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,SEPHS1,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,ARHGEF11,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,IL18,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,ALDH1A3,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,FBXO27,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,SSH3,CAMSAP3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,PKN1,TMA16,NUCB2,ETS1,ARHGEF40,GSTP1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,ADD3,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,UNKL,MYL9,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ITGA7,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,N4BP3,PLCG2,LHX6,SRR,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,EVA1A,MBP,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,RUSC2,GNE,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,PPP2R3A,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,PRDX4,FUCA1,SERPINA1,ZNF214,NAT1,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PLXNA1,CCNB1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,STEAP2,AOX1,PACSIN1,RCAN3,LAMP2,LOC81691,KIFC2,SNTB2,PBK,CASP9,NBPF3,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,NKD1,FAM110C,DHTKD1,SARAF,EIF4EBP2,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,BDH1,SORL1,PIKFYVE,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,AMER1,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,PRKAG2,DCK,CSNK1G1,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,RNF182,SNN,AIFM2,MNS1,APLP2,ZNF75D,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,NIN,PRDM11,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,CSTF2,PGM2L1,GPER1,ETAA1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,TSEN34,SH3KBP1,ABCD4,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,EDNRA,CXXC4,MDK,NEIL1,ZNF114,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,RFX5,NCEH1,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,HMG20B,AMDHD1,GLCE,GNAS,FECH,NUDT16,ONECUT1,PLPP3,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,MAP3K3,GCA,ZNF525,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,ARMC7,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,IL17RB,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,DHRS2,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 7.796e-13 | -27.88 | HALLMARK_TNFA_SIGNALING_VIA_NFKB | MSigDB lists | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 198 | 55 | 17758 | 1761 |
DDX58,NFKBIE,IL15RA,TRIP10,SDC4,TAP1,IL18,SNN,PHLDA1,TNFSF9,IER3,CCND1,BTG3,CYR61,SLC16A6,ZFP36,IL6ST,FJX1,FOSB,DRAM1,BCL6,SGK1,KLF9,PTPRE,TIPARP,ATP2B1,HES1,TGIF1,RIPK2,TNIP1,NR4A1,PLAUR,SAT1,LITAF,PTGER4,DUSP4,RNF19B,FOS,CD83,SOCS3,IRS2,ETS2,PLK2,CSF1,NFKBIA,SLC2A6,NR4A3,NR4A2,GEM,ICOSLG,F2RL1,IFIH1,MAFF,ABCA1,EHD1 |
| 8.090e-13 | -27.84 | DELYS_THYROID_CANCER_UP | MSigDB lists | DELYS_THYROID_CANCER_UP | 438 | 93 | 17758 | 1761 |
KLK10,ST14,S100A11,GALNT12,EPHA4,IL13RA1,SDC1,IER3,CCND1,DAPK2,APLP2,RPS6KA2,RGS3,ALDH1A3,PAPSS1,PASK,CDH3,TACSTD2,ECE1,CTTN,ARMCX6,TIAM1,TIPARP,PTPRE,S100A13,CKS2,CYP1B1,CPD,CD55,PTPRU,S100A4,KLK6,ARHGDIB,LOXL2,ROR1,DUSP4,ITPR3,MAP3K6,TP53I3,ABR,DPYSL3,MDK,ALDH3B1,GPRC5B,KCNK1,MAP2,PTK7,CORO1C,P4HA2,MRC2,IGFBP6,LGALS3,LRP4,SDC4,EPS8,ETV5,PBX3,GDF15,CRABP2,DHRS3,S100A2,NRP2,ELF3,ADORA1,ITGA3,CTSC,KCNN4,AIM1,FJX1,FXYD5,ERBB3,IGSF3,NFE2L3,DDB2,PRSS23,BCL9,UBE2A,PDE5A,NPC2,STX3,FAS,KLHL2,PTPRF,ENDOD1,SERPINA1,COL13A1,DTX4,S100A5,CTSA,ATP1B3,MAP3K5,ACOT7,DOCK9 |
| 8.770e-13 | -27.76 | chrxq22 | MSigDB lists | chrxq22 | 75 | 31 | 17758 | 1761 |
FRMPD3,TBC1D8B,FAM199X,CENPI,TSC22D3,CXorf57,MORC4,PSMD10,DIAPH2,COL4A5,MORF4L2,NUP62CL,TCEAL8,BEX2,MUM1L1,ATG4A,XKRX,TMEM164,RNF128,NGFRAP1,TIMM8A,HNRNPH2,TSPAN6,AMMECR1,TCEAL4,PGRMC1,CSTF2,ACSL4,DRP2,WBP5,NXT2 |
| 9.297e-13 | -27.70 | NUYTTEN_EZH2_TARGETS_DN | MSigDB lists | NUYTTEN_EZH2_TARGETS_DN | 957 | 164 | 17758 | 1761 |
ADD1,EPAS1,DNAJC3,NDC80,TGOLN2,CCNB1,PJA2,CENPN,FANCI,EPCAM,WEE1,C7orf49,UBE2T,METTL7A,TSPAN6,IMPAD1,SLC44A1,FUT1,TRPC1,HYLS1,MARCH2,PACSIN1,MYBL1,SP5,CYP1B1,LAMP2,PLK1,PCGF5,CENPA,PBK,CASP9,F12,CDK1,PRIM1,KDM4D,RBM47,HPSE,KCNK1,HOXA9,ZNF165,EIF4EBP2,F2RL1,E2F8,HJURP,TBC1D1,ITGA6,MTL5,ASB9,KIF23,PHLPP1,TNFRSF19,UBE2Q2,PAIP2B,NEK2,MDFIC,SLC12A2,ALDH3A2,GPR161,EPB41L5,REC8,MRPS33,KIF20A,PQLC3,TBC1D8B,ADCK3,LPGAT1,EIF2AK1,ANTXR1,C3orf58,NFIB,DCP2,GLCE,FAM64A,DCK,PHLPP2,CDCA5,PRPS2,FAM83D,AGBL5,AURKA,MAL2,NDE1,CCNB2,HOOK1,CCNE2,SPC25,DLGAP5,FOXM1,PTTG1,TDRKH,RNF182,NUF2,GRK6,STIL,ARHGEF16,SYTL2,CCND1,SS18,RNF220,SP100,KIF14,RTKN2,F2R,ETV4,ZNF365,MED30,MAP3K3,FZD4,SYNE2,CDC20,KCTD2,H2AFV,FANCE,AMZ2,BFSP1,PPP2R5A,INPP4B,VSIG10,C1orf43,REEP4,ISOC1,CBX7,CMTM4,GLIS3,MAN2B2,CMAS,GOLIM4,PACSIN2,DEPDC1,CENPI,CDCA8,OSGIN2,SWI5,SLC25A43,LBR,VPS26A,FZD6,SIRPA,SAC3D1,SGPL1,TOP2A,ADD3,ALG13,BUB1,IQGAP3,HMMR,SYPL1,HES1,SHMT1,ZWINT,PSMB4,ASPM,MRS2,SYBU,C2orf69,AIF1L,BORA,KLHL2,ACADSB,CENPE,CEP41,UBE2C,PTGES,DIS3L |
| 9.733e-13 | -27.66 | PH/PTB_dom | interpro domains | IPR011993 | 379 | 84 | 18293 | 1814 |
SPRED1,MTM1,NF2,SPTB,ARHGEF16,EPS8L2,ARHGEF10L,ACAP2,ELMO2,SHC3,DOK4,OSBPL3,RGS3,PLCG2,DAB2IP,RTKN2,EPB41L4B,TLN2,TIAM1,FRS3,AKT1,PLEKHO1,EZR,TNS1,ANLN,ADRBK2,ARHGEF26,ABR,IRS2,PLCG1,PLEKHG6,PLCH1,ARHGEF19,TRIOBP,PLEKHG1,SPTBN5,EPB41L4A,GAB1,FGD1,ARAP3,ARHGEF3,FRMD4A,ARHGEF11,TBC1D1,CIT,FRMD6,RASA2,EPS8,TEC,SBF1,PHLPP1,ARHGEF40,TNS3,ADRBK1,RALGPS2,ANKS1B,RANBP1,EXOC8,PLEKHF1,CADPS2,MYLIP,FARP2,EPB41L5,RASGRF1,ARAP2,PLEKHA6,ARHGEF28,SPATA13,SNTB1,MAPK8IP1,RASA1,FRMD4B,ARHGAP24,DGKH,SWAP70,PLEKHH2,FGD6,PLD1,TBC1D4,AFAP1,ARHGEF9,DEF6,DOCK9,ARHGEF4 |
| 1.010e-12 | -27.62 | neurogenesis | biological process | GO:0022008 | 1664 | 257 | 16441 | 1675 |
SSH1,RET,HEXB,NRG2,PSME1,PLXNA1,CAMK1D,NCS1,GRM5,CALM2,CDKN2C,WEE1,PSMD1,SEMA3G,PACSIN1,ZBTB18,TIAM1,TFAP2C,ARF4,PLCG1,LIMK1,PLK2,NKD1,UNC5B,ITPKA,ARF6,LZTS1,SEMA6B,SCN5A,CDKN1C,SOX9,SLC1A3,ITGA3,FRY,FLRT3,MEGF8,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,DGKG,RIMS2,MMD,CALM1,EPHA1,NFIB,PSMA4,STX3,RASA1,PTPRF,SEMA4D,MATN2,CLMN,AURKA,NR4A2,GDF11,ARPC2,NDE1,EHD1,SPRED1,FOXO6,RPS6KA1,IQGAP1,CDH1,DACT1,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,EPHA10,IRS2,JAK1,AXL,SLC9A6,SIPA1L1,NRG1,RGS14,COBL,WASF3,CTHRC1,SDC4,PBX3,PLPPR4,SPR,EFNB1,FGF19,SIX4,TEAD3,NEO1,IGSF9,PTEN,CD9,BAX,ATP8B1,ERBB3,S100A6,FARP2,RASGRF1,TGIF1,B3GNT2,ARHGEF28,FMN1,TACC1,RAPGEF2,GRIN1,YES1,CDK5RAP1,CNTNAP1,PITX2,FGFR2,NR4A3,RYK,GRIN2D,GPER1,ITGAV,FZD5,WDR62,ARSB,RGMA,MYL9,EMX1,CASP3,UGT8,EPHA4,CUL4B,ARFGEF1,MPP5,PDGFB,CACNB4,DNER,TMC1,SPTB,PLS3,RPS6KA2,SHC3,IL6ST,DPYSL2,DLG1,TRPC1,DUSP10,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,CELSR2,EZR,KLK6,CDK1,RHEB,DPYSL3,HS6ST1,GPRC5B,MAP2,MYL12B,GRN,RUNX2,SERPINE2,RASA2,ETV5,CALM3,CNTNAP2,IGF1R,GATA2,KIF13B,COL6A1,WNT3A,CCDC88A,DPYSL5,RGMB,HMG20B,SCRIB,TCF7,RANBP9,CDK5R1,CSF1,PLPP3,TMEM30A,PITPNA,SEMA3A,JAK3,KLF7,NF2,PSME2,HDAC11,TP53,ERBB2,PHLDA1,PDGFA,ARTN,FRYL,LMO4,LHX6,BCL6,DIXDC1,TWIST1,NOTCH3,FRS3,TIMP2,AKT1,CDC20,DAG1,MYL12A,ARHGAP35,PTPRJ,PTK7,BHLHB9,PEX2,SPTBN5,EFNA5,LIFR,BIN1,COL9A3,ADGRG1,ARHGEF11,CIT,LRP4,PSMD10,TGFBR1,COL4A5,CRABP2,PPP2R3A,NRP2,HDAC9,KIF5B,CDK16,LLGL2,MYCL,BMP7,TFAP2A,KIAA0319,SGK1,TLE6,HES1,RHOA,PSMB4,ASPM,STMN3,RUNX3,FAT4,PGRMC1,SOX8,L1CAM |
| 1.063e-12 | -27.57 | extracellular membrane-bounded organelle | cellular component | GO:0065010 | 2742 | 380 | 17570 | 1756 |
LAMP1,GAA,TXN,HSPG2,ATP8A1,DNAJC3,HEXB,FBXO2,PSME1,IL18,LYNX1,NANS,PLXNA1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,ALDH1A3,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,PTER,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,GNS,DOPEY2,ITGA3,SNX18,MEGF8,ATP5H,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,RIMS2,GFPT1,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FAS,PTPRF,SCARB2,NCOA3,SLC4A4,MDH1,MAL2,ARPC2,CFAP20,SERPINB1,EHD1,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,FTH1,KCTD12,CD274,MVB12B,PRKACA,DDR1,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,EPHB4,ACSL4,TSPAN1,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,COL6A2,FZD4,SYNE2,CYS1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,EPHA10,ALDH3B1,STK26,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,BAX,CD9,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,PVRL4,PDGFC,ALDH2,B3GNT2,SHMT1,PLSCR1,FURIN,PARP4,C1GALT1C1,AK4,YES1,BLVRA,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,ACOT7,CYBRD1,RGMA,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,NDRG2,F11R,MPP5,ERP29,SDC1,EPCAM,SUSD2,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,DLG1,AKR1B1,RP2,MYH14,CTTN,S100A13,NEB,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,ZNF114,GPRC5B,UEVLD,ARRDC1,CAB39,GLA,MYL12B,CPPED1,CAPN1,GRN,PRSS8,LASP1,FAM213B,LGALS3,FXYD3,CALM3,ASAH1,PM20D2,NCKAP1,RAB6A,FBLN1,ANO1,CA2,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,PROM2,UGP2,PSME2,HDAC11,CTDSPL,COL18A1,MRAS,EFR3A,PLCG2,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,CTH,CHP1,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,IGSF8,GLO1,CD40,MYL12A,DAG1,ATP1A1,PTPRJ,BHLHB9,SECTM1,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,MAN2B2,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,FAM63A,ALDH7A1,MYO5A,ATP2B1,FAH,SYPL1,PGM1,RHOA,RAB3B,FBLN5,PSMB4,IFITM3,CRB3,GUSB,PLAUR,GGH,RNPEP,SCRN2,PRDX4,ENDOD1,CTSL,FUCA1,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,DHRS2,PRCP,CTSV,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 1.063e-12 | -27.57 | extracellular exosome | cellular component | GO:0070062 | 2742 | 380 | 17570 | 1756 |
LAMP1,GAA,TXN,HSPG2,ATP8A1,DNAJC3,HEXB,FBXO2,PSME1,IL18,LYNX1,NANS,PLXNA1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,ALDH1A3,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,PTER,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,GNS,DOPEY2,ITGA3,SNX18,MEGF8,ATP5H,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,RIMS2,GFPT1,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FAS,PTPRF,SCARB2,NCOA3,SLC4A4,MDH1,MAL2,ARPC2,CFAP20,SERPINB1,EHD1,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,FTH1,KCTD12,CD274,MVB12B,PRKACA,DDR1,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,EPHB4,ACSL4,TSPAN1,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,COL6A2,FZD4,SYNE2,CYS1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,EPHA10,ALDH3B1,STK26,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,BAX,CD9,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,PVRL4,PDGFC,ALDH2,B3GNT2,SHMT1,PLSCR1,FURIN,PARP4,C1GALT1C1,AK4,YES1,BLVRA,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,ACOT7,CYBRD1,RGMA,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,NDRG2,F11R,MPP5,ERP29,SDC1,EPCAM,SUSD2,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,DLG1,AKR1B1,RP2,MYH14,CTTN,S100A13,NEB,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,ZNF114,GPRC5B,UEVLD,ARRDC1,CAB39,GLA,MYL12B,CPPED1,CAPN1,GRN,PRSS8,LASP1,FAM213B,LGALS3,FXYD3,CALM3,ASAH1,PM20D2,NCKAP1,RAB6A,FBLN1,ANO1,CA2,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,PROM2,UGP2,PSME2,HDAC11,CTDSPL,COL18A1,MRAS,EFR3A,PLCG2,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,CTH,CHP1,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,IGSF8,GLO1,CD40,MYL12A,DAG1,ATP1A1,PTPRJ,BHLHB9,SECTM1,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,MAN2B2,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,FAM63A,ALDH7A1,MYO5A,ATP2B1,FAH,SYPL1,PGM1,RHOA,RAB3B,FBLN5,PSMB4,IFITM3,CRB3,GUSB,PLAUR,GGH,RNPEP,SCRN2,PRDX4,ENDOD1,CTSL,FUCA1,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,DHRS2,PRCP,CTSV,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 1.135e-12 | -27.50 | MODULE_54 | MSigDB lists | MODULE_54 | 253 | 64 | 17758 | 1761 |
ARHGAP11A,CCNE2,DLGAP5,NQO1,FOXM1,PTTG1,NDC80,NUF2,CCNB1,BARD1,APOBEC3B,CDKN2C,UBE2T,CDH1,IMPAD1,KIF14,PLK4,MANF,OAS3,CKS2,PLK1,CENPA,PBK,CDC20,NUSAP1,PKMYT1,CCNF,ANLN,SLC25A5,CDK1,PRIM1,E2F8,HJURP,CDKN1C,DEPDC1,CKAP2,KIF23,GPSM2,LBR,CTNNBIP1,TOP2A,RANBP1,NEK2,AHCY,BUB1,TNFRSF12A,GAD1,HMMR,ZWINT,ASPM,MYBL2,GGH,AIF1L,KIF11,PRDX4,FAM64A,CDCA5,FAM83D,AURKA,CENPE,HMGA1,CCNB2,UBE2C,MELK |
| 1.176e-12 | -27.47 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | 166 | 49 | 17758 | 1761 |
LASP1,PCOLCE,HSPG2,EPAS1,ST14,SOX9,CYB561,IL13RA1,TGFBR1,ETS1,CA8,ANO1,SIRPA,FZD6,RAD23A,IER3,APLP2,WEE1,CYR61,CALD1,VASN,F2R,S100A6,CPD,HES1,TGIF1,PDGFC,TIMP2,AKT1,GUSB,FZD4,SNTB2,SAT1,UTRN,TNS1,COL7A1,NFIB,DPYSL3,GALNT3,PIAS3,ATP1A1,ETS2,PLOD2,BMP1,FHL1,ITGAV,COL16A1,EHD1,EGLN1 |
| 1.185e-12 | -27.46 | GNF2_HMMR | MSigDB lists | GNF2_HMMR | 47 | 24 | 17758 | 1761 |
HMMR,PLK1,ZWINT,KIF20A,DLGAP5,FOXM1,ASPM,CDC20,NDC80,CDCA8,NUSAP1,KIF11,CDK1,TOP2A,PLK4,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,E2F8,MELK,CKS2 |
| 1.292e-12 | -27.37 | negative regulation of cellular process | biological process | GO:0048523 | 4068 | 535 | 16441 | 1675 |
HECA,ACACB,ADD1,DNAJC3,FBXO2,IL18,MORF4L2,SYTL4,BARD1,GRM5,CALM2,CDKN2C,PSMD1,CABP1,CRY2,SEMA3G,APOBEC3G,SMARCA2,TNIP1,CDA,TFAP2C,PRKAR2B,LOXL2,ARF4,ABR,PIAS3,ENPP1,MID1IP1,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,ARF6,HSPB1,E2F8,NFKBIE,NUAK1,ITGA6,SOX9,RAB23,FAM21C,MERTK,LMNA,ELF3,TFAP4,PAIP2B,NEK2,MYDGF,SALL4,ERO1A,NPHP3,PSMA4,PLIN5,NCOA3,ETS2,SEMA4D,ITPR1,AURKA,CLMN,STK39,GDF11,SERPINB1,XDH,EGLN1,GRHL2,INPP5D,PTTG1,RGS20,PKP2,PRKACA,APC2,CCND1,CDH1,SP100,DACT1,DLG3,CDKN2D,ETV4,MX1,CAMSAP3,RIPK2,APOBEC3D,FZD4,HTATIP2,SNX12,NFIX,IRS2,CORO1C,WFS1,AXL,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TCAF1,TNRC6C,NKX3-1,CKAP2,ANO9,PKN1,ETS1,GSTP1,TIPRL,NEO1,CTNNBIP1,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,CRTAP,PLSCR1,RAPGEF2,PIK3R1,GRIN1,PITX2,NR1D2,ACVRL1,NR4A3,ITGAV,HMGA1,FHL1,OSR1,SIGIRR,CNOT8,EPHA4,ARFGEF1,LMCD1,NDRG2,TP53I11,HDAC6,PDGFB,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,IL6ST,ELF5,PASK,MITF,DUSP10,PLK1,THRB,CD55,KCNIP3,ING1,CBX6,EZR,PRKRA,SESN1,CDK1,RHEB,OPTN,DPYSL3,TRIM9,KLF12,HOXA9,RAB11FIP1,PRKCDBP,KLF11,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,LGALS3,DNAJB2,RASA2,UBASH3B,PDCL,HES2,DHRS3,FBLN1,IGF1R,GATA2,TBCD,MDFIC,PIM1,WNT3A,CYP26B1,STRADB,SCRIB,EIF2AK1,IFIT3,G2E3,CDK5R1,NLRC5,SEMA3A,IFI6,NF2,FOXM1,P3H2,CTDSPL,TP53,ERBB2,STIL,CYP26A1,SYTL2,IER3,PDGFA,LMO4,PLCG2,BCL6,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,DVL2,CTH,SULF2,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,PTGER4,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,RBL1,STK38,IRF7,ARFGEF3,PINK1,PACSIN2,CPEB4,ADGRG1,DAP,PSMD10,NKRF,PPP2R3A,SH2D4A,FZD6,CD109,FOXP2,TFAP2A,UBE2J1,TRIM21,BUB1,KLF9,FAIM,NFE2L3,HES1,RHOA,PSMB4,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,PELI3,MAPK8IP1,PRDX4,BANK1,SERPINA1,TWSG1,SCG2,NMI,NDFIP1,TBC1D4,UBE2C,PTGES,HIPK3,ZBTB33,PKIA,PPP4R4,TXN,LGR4,TSC22D3,PSME1,CAMK1D,VASH1,CCNB1,FAM101B,CTGF,RGS3,ZFP36,FOSB,IL31RA,PIK3CA,IRF2,TACSTD2,PACSIN1,ZBTB18,ACVR1C,PBK,SLC35C1,AGO4,PIF1,SAV1,CCNF,SLC25A5,POR,AHRR,SLC25A4,PLK2,NKD1,PRDM5,SERPINI1,EIF4EBP2,UNC5B,F2RL1,LZTS1,SEMA6B,CDKN1C,SLC25A27,MECOM,ITGA3,CYR61,PIK3AP1,VASN,BHLHE41,PRKG1,DAPK1,SORL1,GPR161,SOCS5,EPB41L5,MFI2,AMER1,CALM1,EPHA1,NFIB,RASA1,FAS,AP1AR,PRKAG2,PLEKHH2,SFMBT1,CABIN1,NR4A2,PER3,SPRED1,S100A11,NLRX1,IQGAP1,CAST,DDIT4L,RPS6KA1,THRA,FTH1,CD274,BCL2L1,ZFYVE9,APOBEC3B,APLP2,NOV,CDKN1B,DAB2IP,IFIT1,PDE4D,LGMN,NR2C1,SEMA3B,DRAP1,PRKCQ,PKMYT1,RAD17,H2AFV,FZD7,PPP2R5A,TRIOBP,SLC27A1,NRG1,KLF5,CBX7,IGFBP6,DEPDC1,EPS8,APOBEC3H,FGF19,SIX4,WWP2,SNTA1,FAM111A,E2F7,GNB5,RNF128,PTEN,CD9,ATP8B1,ERBB3,CNOT6L,CITED2,TRIM62,SPRY2,OSGIN1,NCOA2,TGIF1,ZWINT,FURIN,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,LRRK1,GPER1,FZD5,ESPL1,CPEB2,JARID2,CASP3,LTBP1,CRYM,ERP29,SH3KBP1,EPCAM,TSPAN6,SIVA1,DLG1,CTTN,SLC39A10,PTPRE,CYP1B1,TRIM8,ITCH,ARHGDIB,EDNRA,CXXC4,MDK,NEIL1,MADD,CAB39,ADIPOR1,GLA,RAP1GAP,ARAP3,SERPINE2,CALM3,PHLPP1,FXYD5,C10orf54,RFX5,ETV7,MDFI,ELK3,OXR1,HMG20B,PDE5A,NUBP1,RANBP9,ONECUT1,NUDT16,PLPP3,CGREF1,NFKBIA,SH3BP4,YOD1,EGFL7,JAK3,SHROOM2,RARG,TOB1,PROM2,GAS2L1,LZTFL1,IL15,PSME2,COL18A1,OSR2,SVBP,SETDB2,KIF14,FABP6,TWIST1,DIXDC1,F2R,CHP1,PTPRU,GLO1,ERBB2IP,DUSP4,SOCS3,ARHGAP35,JADE1,BHLHB9,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,LIFR,ABCA1,GLIS3,GCLM,SORT1,CIT,LRP4,AES,TGFBR1,NOTUM,TRIB2,HMGXB4,HDAC9,TOP2A,IRF2BPL,CARD8,TAF1B,ADRBK1,ADORA1,BMP7,KIAA0319,NR4A1,GCLC,ASPM,RGCC,MBNL3,RUNX3,LEPR,ARHGAP24,SWAP70,DHRS2,RAP2C,SPINT2,CTSV,ARRB1,SOX8,AHR,ABCG1,CD33 |
| 1.328e-12 | -27.35 | extracellular vesicle | cellular component | GO:1903561 | 2755 | 381 | 17570 | 1756 |
LAMP1,GAA,TXN,HSPG2,ATP8A1,DNAJC3,HEXB,FBXO2,PSME1,IL18,LYNX1,NANS,PLXNA1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,ALDH1A3,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,PTER,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,GNS,DOPEY2,ITGA3,SNX18,MEGF8,ATP5H,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,RIMS2,GFPT1,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FAS,PTPRF,SCARB2,NCOA3,SLC4A4,MDH1,MAL2,ARPC2,CFAP20,SERPINB1,EHD1,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,FTH1,KCTD12,CD274,MVB12B,PRKACA,DDR1,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,EPHB4,ACSL4,TSPAN1,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,COL6A2,FZD4,SYNE2,CYS1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,EPHA10,ALDH3B1,STK26,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,BAX,CD9,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,PVRL4,PDGFC,ALDH2,B3GNT2,SHMT1,PLSCR1,FURIN,PARP4,C1GALT1C1,AK4,YES1,BLVRA,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,ACOT7,CYBRD1,RGMA,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,NDRG2,F11R,MPP5,ERP29,SDC1,EPCAM,SUSD2,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,DLG1,AKR1B1,RP2,MYH14,CTTN,S100A13,NEB,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,ZNF114,GPRC5B,UEVLD,ARRDC1,CAB39,GLA,MYL12B,CPPED1,CAPN1,GRN,PRSS8,LASP1,FAM213B,LGALS3,SERPINE2,FXYD3,CALM3,ASAH1,PM20D2,NCKAP1,RAB6A,FBLN1,ANO1,CA2,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,PROM2,UGP2,PSME2,HDAC11,CTDSPL,COL18A1,MRAS,EFR3A,PLCG2,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,CTH,CHP1,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,IGSF8,GLO1,CD40,MYL12A,DAG1,ATP1A1,PTPRJ,BHLHB9,SECTM1,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,MAN2B2,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,FAM63A,ALDH7A1,MYO5A,ATP2B1,FAH,SYPL1,PGM1,RHOA,RAB3B,FBLN5,PSMB4,IFITM3,CRB3,GUSB,PLAUR,GGH,RNPEP,SCRN2,PRDX4,ENDOD1,CTSL,FUCA1,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,DHRS2,PRCP,CTSV,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 1.328e-12 | -27.35 | extracellular organelle | cellular component | GO:0043230 | 2755 | 381 | 17570 | 1756 |
LAMP1,GAA,TXN,HSPG2,ATP8A1,DNAJC3,HEXB,FBXO2,PSME1,IL18,LYNX1,NANS,PLXNA1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,ALDH1A3,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,CARHSP1,PTER,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,HLA-E,RAB23,NDUFA4,TTYH3,GNS,DOPEY2,ITGA3,SNX18,MEGF8,ATP5H,VASN,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,RIMS2,GFPT1,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FAS,PTPRF,SCARB2,NCOA3,SLC4A4,MDH1,MAL2,ARPC2,CFAP20,SERPINB1,EHD1,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,FTH1,KCTD12,CD274,MVB12B,PRKACA,DDR1,EPS8L2,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,EPHB4,ACSL4,TSPAN1,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,COL6A2,FZD4,SYNE2,CYS1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,EPHA10,ALDH3B1,STK26,AXL,ISOC1,WASF3,PCOLCE,IGFBP6,EPS8,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,EFNB1,LGALS3BP,HLA-A,WWP2,FUT2,ITGB8,CTSC,MGAT4A,CST3,FUT8,BAX,CD9,ADAM15,SLC44A2,WWP1,IGFBP2,TAGLN2,S100A6,PVRL4,PDGFC,ALDH2,B3GNT2,SHMT1,PLSCR1,FURIN,PARP4,C1GALT1C1,AK4,YES1,BLVRA,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,ACOT7,CYBRD1,RGMA,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,NDRG2,F11R,MPP5,ERP29,SDC1,EPCAM,SUSD2,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,DLG1,AKR1B1,RP2,MYH14,CTTN,S100A13,NEB,THRB,NLRP4,CD55,ITCH,CR2,EZR,ARHGDIB,IDH1,CDK1,RHEB,ZNF114,GPRC5B,UEVLD,ARRDC1,CAB39,GLA,MYL12B,CPPED1,CAPN1,GRN,PRSS8,LASP1,FAM213B,LGALS3,SERPINE2,FXYD3,CALM3,ASAH1,PM20D2,NCKAP1,RAB6A,FBLN1,ANO1,CA2,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,PRPS2,SH3BP4,FAM213A,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,PROM2,UGP2,PSME2,HDAC11,CTDSPL,COL18A1,MRAS,EFR3A,PLCG2,VAT1,GOT1,ECE1,MINPP1,LMAN1,PDIA6,GM2A,CTH,CHP1,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,IGSF8,GLO1,CD40,MYL12A,DAG1,ATP1A1,PTPRJ,BHLHB9,SECTM1,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,MAN2B2,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,FAM63A,ALDH7A1,MYO5A,ATP2B1,FAH,SYPL1,PGM1,RHOA,RAB3B,FBLN5,PSMB4,IFITM3,CRB3,GUSB,PLAUR,GGH,RNPEP,SCRN2,PRDX4,ENDOD1,CTSL,FUCA1,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,DHRS2,PRCP,CTSV,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 1.333e-12 | -27.34 | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | MSigDB lists | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | 574 | 112 | 17758 | 1761 |
UNKL,HECA,SLC2A4,GRHL2,EPAS1,TRIP10,VANGL1,RPS6KA1,THRA,EPHA4,TGOLN2,PLXNA1,FAM46C,ZFYVE9,CCND1,WEE1,BTG3,DPYSL2,LHX6,ENPP5,SNX16,NTN4,CRY2,ACSL4,TMEM64,EGLN3,RASGEF1A,MAP3K3,TIMP2,CELSR2,ITCH,FOXJ2,PTGFRN,ARHGAP35,MFAP3L,HLF,KLF12,RBL1,LIMK1,ZNF367,STK38,LRIG1,RAB11FIP1,ZNF704,AGFG2,KLF11,GAB1,ABCA1,PRR15,NR2C2,FGD1,ARHGEF3,FRMD4A,ARHGEF11,FRMD6,HABP4,FAM134A,ARL4C,KIF23,PBX3,EFNB1,VPS26A,NRP2,DNAJB9,M6PR,MARCH8,UBE2Q2,ITGB8,RNF128,GNB5,PTEN,CALD1,LYPD6,BHLHE41,FJX1,MAP3K9,UBE2J1,SORL1,FAM102A,KLF9,PANX2,CYP26B1,DPYSL5,ELK3,TBC1D8B,LPGAT1,OXR1,ANO6,EIF5A2,PIK3R1,SYBU,FURIN,PPARA,YES1,FNDC3A,TP53INP2,NCOA3,CSNK1G1,PHLPP2,RAP2C,NETO2,NR4A3,CLIP4,FAM117A,SFMBT1,YOD1,NR4A2,MAP3K5,OSR1,NIPA1,PKIA,RGMA |
| 1.643e-12 | -27.13 | regulation of biological quality | biological process | GO:0065008 | 3288 | 447 | 16441 | 1675 |
SUN1,LAMP1,GAA,TXN,SSH1,ADD1,LGR4,ATP8A1,HEXB,RET,TAP1,PSME1,ISOC2,PLXNA1,SYTL4,BARD1,GRM5,SLC9A7,CALM2,WEE1,CYP1A1,SESN3,PQLC2,PSMD1,MUC4,CTGF,STIM1,ZFP36,ALDH1A3,IL31RA,STEAP2,PIK3CA,CLDN4,IRF2,CRY2,SEMA3G,PIK3CD,ACOX2,ZBTB18,TIPARP,ERAP2,XKR8,LAMP2,TNIP1,ACVR1C,PRKAR2B,PIF1,F12,LDB2,SAV1,ABR,PRIM1,PIAS3,ENPP1,CARHSP1,PLCG1,PLK2,LIMK1,ATP7B,NOD2,HDAC1,EIF4EBP2,TMOD2,ITPKA,ARF6,HSPB1,F2RL1,FGD1,SEMA6B,SCN5A,NFKBIE,SCOC,ITGA6,DGKQ,CALB2,SOX9,MTL5,SLC25A27,KIF23,SLC1A3,MERTK,MECOM,TFAP4,ITGA3,MEGF8,RIMS3,FLRT3,PRKG1,SORL1,TNFRSF12A,CACNA1D,DGKG,MYLIP,SYTL3,NUP85,RIMS2,SLC37A1,MFI2,CALM1,ANO6,ERO1A,NPC2,ATP8B3,NPHP3,TP53INP2,GNA11,PSMA4,SFXN5,DCP2,PLIN5,STX3,RASA1,FAS,DGKH,SLCO4A1,GABRD,PLEKHH2,SLC4A4,SEMA4D,CSNK1G1,ITPR1,SLC4A3,FGD6,AURKA,STK39,ARPC2,CFAP20,NUP58,XDH,ADAMTS16,EGLN1,EHD1,DOCK9,PLA2G4A,MTM1,CCDC109B,SLC2A4,PAPSS2,THRA,INPP5D,ATP2C2,PKP2,FTH1,BCL2L1,PRKACA,DDR1,CCND1,NOV,APLP2,SCNN1A,SP100,DACT1,CNNM4,DAB2IP,PDE4D,IFIT1,TSPAN1,MYT1,SCN3A,SEMA3B,MYO5B,ENPP4,SSH3,FZD4,SYNE2,PRKCQ,SLC11A2,ATP1B1,RAB38,ITPR3,ATP10D,IRS2,POPDC3,SHROOM3,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,TRIOBP,NRG1,PRIMA1,RGS14,WASF3,ATP9A,EPS8,HABP4,PDIA3,CTSZ,ANO9,PKN1,GSTP1,SRPX2,ADGRB2,SIX4,WWP2,PDIA4,SGPL1,SLC25A36,NEO1,CTNNBIP1,SNTA1,RNF128,IGSF9,PTEN,SGK3,CD9,BAX,ATP8B1,TMBIM6,MAPK11,CNOT6L,TPCN1,CRTAP,RASGRF1,LCA5,ALDH2,PLSCR1,FMN1,RAPGEF2,PIK3R1,EIF5A2,GRIN1,FURIN,C1GALT1C1,YES1,KIF11,ACADSB,RAB11FIP2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ERAP1,ITGAV,GPER1,CENPE,LRRK1,USF2,SLC25A38,CYBRD1,MYL9,EMX1,LTBP1,CASP3,EPAS1,CRYM,ARFGEF1,F11R,NENF,VARS2,ITPR2,HDAC6,CACNB4,PDGFB,SLC8B1,SPTB,SH3KBP1,HTR1D,RPS6KA2,SIVA1,DPYSL2,ABCA2,DLG1,AKR1B1,TRPC1,SUN3,RAB20,MYH14,CTTN,TLN2,ANO4,SLC39A10,NEB,S100A13,RASGRP1,CYP1B1,PLK1,THRB,CD55,CELSR2,STRIP2,NFE2L1,EZR,KLK6,EDNRA,TRIM9,KCNMB4,GPRC5B,KCNK1,ADIPOR1,PIEZO1,MYL12B,MAFF,PCSK5,PRKAA2,ARAP3,SERPINE2,PEX6,BVES,ETV5,ABCG2,CALM3,NCKAP1,DHRS3,FBLN1,ANO1,B4GALNT1,CA2,GATA2,KCNN4,WNT3A,GAD1,SLC12A2,MDFI,KDELR1,CYP26B1,GYLTL1B,HMG20B,PDE5A,SCRIB,EIF2AK1,PDK3,NUBP1,STEAP1,CDK5R1,RASGRP2,FECH,GNAS,MAPKAPK2,PLPP3,ITGA7,CSF1,TMEM30A,NFKBIA,CTSA,ATP1B3,SHROOM2,CCNB2,JAK3,SEMA3A,RARG,NF2,PSME2,TMX4,PDIA5,TP53,EMP2,BCAP31,CYP26A1,SYTL2,IER3,PDGFA,ATP6V0B,CYP4F11,PLCG2,BCL6,CDH3,GOT1,ECE1,TMEM64,SCN2A,LMAN1,F2R,PDIA6,GM2A,CHP1,SIRT1,PPIF,CLCN3,AKT1,CCSAP,CDC20,ACO1,CD40,MYL12A,DAG1,ARHGAP35,ATP13A2,DNAJC10,DUOX1,ALDH5A1,IDE,ATP1A1,PTPRJ,ABHD12,BHLHB9,PEX2,PTBP3,EFNA5,SPTBN5,SYT13,AIFM3,ABCA1,GCLM,FBLIM1,PINK1,CD63,POC1B,LRP4,GABRG2,PSMD10,SELL,CRABP2,SIRPA,SLC9A2,FZD6,KIF5B,ADORA1,ADRBK1,CDK16,SGK1,TRIM21,IQGAP3,SYK,ATP2B1,MYO5A,SUN2,RAB3B,RHOA,PSMB4,ASPM,PLAUR,GCLC,RC3H2,PPARA,TTC7A,BCAR1,TXNDC11,BBS2,RNPEP,DGKE,PRDX4,SWAP70,SERPINA1,DHRS2,PRCP,ARRB1,PPP2R3C,MCUR1,SOX8,PLOD3,NDFIP1,L1CAM,ABCG1,SNPH |
| 1.785e-12 | -27.05 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 722 | 132 | 17758 | 1761 |
ACACB,BCAM,ADD1,FAM199X,HEBP1,ATP8A1,EPHA4,FHDC1,TEX2,F11R,LTBP3,EPCAM,CTGF,STIM1,METTL7A,TSPAN6,RCAN3,TNS1,SESN1,POR,DPYSL3,PGF,ANKRD10,TMEM164,LRIG1,RELL1,GLCCI1,RAP1GAP,CAPN1,TBC1D1,DNAJB2,DHRS3,FBLN1,B3GALNT1,TNS3,BHLHE41,PCYOX1,OPN3,SORL1,LIMCH1,MYLIP,ALDH3A2,MCCC2,EPB41L5,PQLC3,SPATA13,GNAS,NUDT16,SCARB2,CACHD1,PRKAG2,SLC4A4,MATN2,ITPR1,NFKBIA,CLMN,PITPNA,LTBP2,MAP3K5,PLIN3,PER3,TOB1,RNF146,PROM2,SPRED1,GRHL2,HDAC11,ERBB2,KCTD12,DDR1,CDS1,APLP2,ST5,ENPP5,EPB41L4B,ARL4D,LGMN,TMTC1,MBP,C3orf52,SYNE2,PTGER4,HTATIP2,ERBB2IP,DOCK5,ATP1A1,ALDH5A1,ST3GAL1,LIFR,CBX7,MAN2B2,WASF3,ARHGEF3,PINK1,CPEB4,CYB561,SEPP1,H1FX,TMCC3,NEO1,CCDC92,ADD3,ITGB8,LLGL2,PTEN,RRBP1,CST3,FAM63A,SGK1,ERBB3,CITED2,TPCN1,GCNT1,HES1,ALDH2,ARAP2,TTC7A,STMN3,FBXO9,SNTB1,LEPR,BSDC1,SERPINA1,NR1D2,FAM117A,ERAP1,FZD5,TBC1D4,HIPK3,CYBRD1,GOLGB1,ABCG1 |
| 1.836e-12 | -27.02 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 792 | 144 | 16441 | 1675 |
MYL9,CASP3,RET,EPHA4,NRG2,PSME1,ITPR2,PDGFB,SPTB,SH3KBP1,CALM2,RPS6KA2,PSMD1,CTGF,ELMO2,SHC3,IL31RA,PIK3CA,PIK3CD,MYH14,TIAM1,TIPARP,RASGRP1,CASP9,PRKAR2B,AGO4,ROR1,ZFAND5,ARF4,ABR,RHEB,PGF,PLCG1,LIMK1,CAB39,HDAC1,EIF4EBP2,HSPB1,GAB1,MYL12B,RRAGD,PCSK5,FGD1,PRKAA2,RASA2,SOX9,CALM3,TEC,NCKAP1,PHLPP1,IGF1R,FLRT3,NCAM1,SOCS5,CALM1,STRADB,EPHA1,ELK1,PSMA4,RASA1,CDK5R1,MAPKAPK2,PRKAG2,PHLPP2,CSF1,NFKBIA,ITPR1,ARPC2,JAK3,SPRED1,SORBS1,REPS2,IQGAP1,PSME2,RPS6KA1,ERBB2,PRKACA,DDR1,ARHGEF16,PDGFA,ATP6V0B,SS18,DOK4,CDKN1B,DAB2IP,EPHB4,RASGEF1A,SULF2,FRS3,AKT1,RIPK2,ERBB2IP,ITPR3,DUSP4,MYL12A,SOCS3,EPHA10,IRS2,PTPRJ,IDE,JAK1,NGFRAP1,AXL,SLC9A6,SIPA1L1,NRG1,SPTBN5,EFNA5,RGS14,MAPK12,SORT1,TNRC6C,ARHGEF3,ARHGEF11,EPS8,PSMD10,FGF19,EFNB1,NRP2,SGPL1,ADRBK1,PTEN,MAPK11,ERBB3,SPRY2,SYK,RASGRF1,PDGFC,ARHGEF28,RHOA,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,BCAR1,GPLD1,FGFR2,GRIN2D,ITGAV,ARHGEF9,ARHGEF4 |
| 1.981e-12 | -26.95 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 16286 | 1681 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.048e-12 | -26.91 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | 592 | 114 | 17758 | 1761 |
SPC25,IL15,NLRX1,ST14,CPT2,DDIT4L,INPP5D,HEXB,MORC4,COL18A1,KCTD12,LYNX1,IL18,F11R,SLC20A1,SDC1,PDGFB,DDR1,PDGFA,ATP6V0B,UBE2T,CNTRL,STIM1,LMO4,FOSB,AOX1,SRR,AKR1B1,SNX16,ACOX2,TINAGL1,ECE1,S100A13,PPIF,CD55,CITED4,UTRN,PRKRA,ICMT,IDH1,STK17B,FZD7,ATP13A2,PGF,ANKRD10,PIAS3,CARHSP1,HS6ST1,PLEKHG6,WIPI1,GDE1,BMP1,OVOL1,SLC27A1,SP6,ITPKA,GLCCI1,LASP1,ENO2,CKAP2,ITGA6,DNAJB2,ARMC7,DGKQ,GDF15,EFNB1,LGALS3BP,DNAJB9,SAC3D1,GNS,DOPEY2,RNF128,ZNRF2,LLGL2,VASN,EXOC8,PCYOX1,DAPK1,DRAM1,FAM102A,ARVCF,TSPAN13,OSGIN1,FAH,OPLAH,ARAP2,ALDH2,MMD,PQLC3,GUSB,NR4A1,CORO2A,LPGAT1,HMG20B,AK4,TCF7,NPC2,BCAR1,TP53INP2,RNPEP,PCTP,STX3,GPLD1,FAS,FUCA1,MMP15,ENDOD1,PRCP,SH3BGRL2,CDK18,CENPE,FZD5,DCBLD1,RUSC1 |
| 2.217e-12 | -26.83 | cell surface receptor signaling pathway | biological process | GO:0007166 | 2257 | 327 | 16441 | 1675 |
LGR4,IL15RA,RET,NRG2,IL18,PSME1,PLXNA1,GRM5,CALM2,PSMD1,CTGF,ELMO2,IL31RA,PIK3CA,IRF2,TACSTD2,PIK3CD,SEMA3G,TIAM1,TIPARP,ACVR1C,CASP9,CDA,PRKAR2B,AGO4,ZFAND5,ARF4,ABR,PGF,PLCG1,LIMK1,NKD1,HDAC1,EIF4EBP2,UNC5B,HSPB1,GAB1,FGD1,SEMA6B,THEMIS2,HLA-E,ITGA6,SOX9,MERTK,TNFRSF19,TSPAN7,MESDC2,ITGA3,MEGF8,FLRT3,DAPK1,TNFRSF12A,CD70,NCAM1,NUP85,SOCS5,STAT4,MICB,CALM1,AMER1,ANO6,EPHA1,NPHP3,ELK1,PSMA4,RASA1,FAS,PTPRF,PRKAG2,SEMA4D,PELI2,CSNK1G1,ITPR1,CABIN1,GDF11,ARPC2,NUP58,SPRED1,REPS2,TCTN2,CD82,INPP5D,RPS6KA1,IQGAP1,IL13RA1,BCL2L1,GRK6,CD274,PRKACA,DDR1,APC2,ZFYVE9,CCND1,SP100,DACT1,DOK4,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,TSPAN1,RASGEF1A,SEMA3B,MX1,RIPK2,FZD4,PRKCQ,PYGO1,ITPR3,FZD7,EPHA10,IRS2,JAK1,NGFRAP1,SLC9A6,AXL,TSPAN18,SIPA1L1,TRABD2A,SLC27A1,NRG1,RGS14,MAPK12,CTHRC1,ARHGEF3,TNRC6C,EPS8,HERC5,BTN3A1,EFNB1,FGF19,HLA-A,ADGRB2,SGPL1,CTNNBIP1,ITGB8,PTEN,FUT8,CD9,BAX,ADAM15,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,FARP2,AMOTL2,RASGRF1,TGIF1,PDGFC,ARHGEF28,BCL9,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,NEURL1B,FOS,GPLD1,ACVRL1,FGFR2,RYK,NR4A3,GRIN2D,ITGAV,FZD5,RGMA,MYL9,CASP3,LTBP1,EPHA4,NDRG2,F11R,ITPR2,SDC1,DNER,PDGFB,CACNB4,SPTB,TRIM68,KREMEN1,SH3KBP1,ZFYVE16,RPS6KA2,ZCCHC12,SHC3,IL6ST,TSPAN6,SIVA1,MITF,MYH14,PTPRE,RASGRP1,TRIM8,CELSR2,USP18,ITCH,CR2,ROR1,RHEB,MDK,CXXC4,MADD,CAB39,ADIPOR1,MYL12B,RRAGD,PCSK5,PRKAA2,RUNX2,LRRFIP2,HLA-F,RASA2,CALM3,TEC,NCKAP1,PHLPP1,FBLN1,IL18R1,IGF1R,HLA-C,C10orf54,ZRANB1,WNT3A,RGMB,STRADB,TCF7,IFIT3,CDK5R1,MAPKAPK2,ONECUT1,CSF1,ITGA7,PHLPP2,PLPP3,NFKBIA,LTBP2,JAK3,SEMA3A,IFI6,RARG,COL16A1,TOB1,RNF146,SORBS1,PSME2,TP53,ERBB2,IL27RA,STIL,ARHGEF16,TTC21B,PDGFA,SS18,ATP6V0B,PLCG2,CDH3,GOT1,DIXDC1,NOTCH3,OAS3,DVL2,SULF2,FRS3,AKT1,PTPRU,ERBB2IP,CD40,DUSP4,MYL12A,SOCS3,DUOX1,PTPRJ,IDE,RBL1,PTK7,TLE1,EFNA5,IRF7,SPTBN5,ABCA1,LIFR,SORT1,CPEB4,ARHGEF11,ADGRG1,LRP4,PSMD10,GDF15,AES,TGFBR1,NOTUM,FZD6,HMGXB4,NRP2,PPP2R3A,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,TRIM21,TSPAN13,SYK,HES1,RHOA,PSMB4,IFITM3,NR4A1,PLAUR,MAML2,PELI3,BBS2,BCAR1,LEPR,HLA-B,TWSG1,DTX4,ARRB1,GEM,ARHGEF9,L1CAM,ZBTB33,ARHGEF4 |
| 2.757e-12 | -26.62 | MODULE_38 | MSigDB lists | MODULE_38 | 447 | 93 | 17758 | 1761 |
MYL9,LTBP1,HSPG2,EPAS1,S100A11,TRIP10,ERBB2,NRG2,SDC1,EMP2,PDGFB,ARHGEF16,CHPF,IER3,CCND1,ST5,CDH1,SH3BP1,FOSB,CLDN4,TACSTD2,ECE1,NOTCH3,LGMN,SMYD5,SMAGP,COL6A2,TIMP2,PTPRU,S100A4,PTPN9,CDA,TFAP2C,PKMYT1,DUSP4,PGF,AGPAT2,WFS1,BMP1,TLE1,ABCA1,MAFF,GRN,PRSS8,PCOLCE,CDKN1C,DCAF7,DNAJB2,BLVRB,ETV5,GNE,ARL4C,GDF15,DHRS3,FBLN1,EFNB1,TEAD3,M6PR,TMEM63A,ITGA3,CYR61,CTSC,LLGL2,LYPD3,GATA2,KCNN4,COL6A1,DAPK1,TFAP2A,IGFBP2,ERBB3,PIM1,CITED2,CLIP2,PLCB2,IGSF3,HES1,PCDH1,MPP1,FURIN,TCF7,CDK5R1,MMP15,FUCA1,TIMP3,ETS2,PVRL2,SEMA4D,DTX4,SLC4A3,LTBP2,JAK3,OCLN |
| 2.993e-12 | -26.53 | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 210 | 56 | 17758 | 1761 |
LMO7,MTM1,MACC1,FRMD6,RASA2,SLC20A1,ETS1,PHLDA1,ELF3,IER3,APOBEC3B,IRF2BPL,WEE1,OTUD1,IGF1R,FOSB,KLF3,CLDN4,TACSTD2,NCEH1,TIPARP,BTBD3,TGIF1,HES1,MBP,CD55,NR4A1,RAPGEF2,PLAUR,ANO6,C3orf52,CASP9,EZR,KLK6,GALNT7,PPP1R14C,FNDC3A,FOS,FRMD4B,SOCS3,ETS2,RND3,PLK2,SH3BP4,NR4A3,NR4A2,NFKBIZ,NRG1,GEM,SEMA3A,F2RL1,COBL,MAFF,TOB1,CPEB2,OCLN |
| 3.277e-12 | -26.44 | generation of neurons | biological process | GO:0048699 | 1584 | 245 | 16441 | 1675 |
MYL9,CASP3,EMX1,UGT8,SSH1,CUL4B,RET,EPHA4,ARFGEF1,NRG2,PSME1,PLXNA1,CAMK1D,DNER,CACNB4,PDGFB,SPTB,TMC1,NCS1,GRM5,PLS3,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,IL6ST,DLG1,DUSP10,TRPC1,NTN4,CTTN,MYH14,SEMA3G,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,CELSR2,EZR,TFAP2C,KLK6,CDK1,ARF4,RHEB,DPYSL3,HS6ST1,PLCG1,GPRC5B,MAP2,LIMK1,PLK2,NKD1,UNC5B,ITPKA,ARF6,MYL12B,LZTS1,GRN,SEMA6B,SCN5A,RUNX2,CDKN1C,SERPINE2,RASA2,ETV5,SOX9,CALM3,CNTNAP2,SLC1A3,ITGA3,IGF1R,FRY,GATA2,FLRT3,MEGF8,KIF13B,COL6A1,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,WNT3A,DGKG,RIMS2,CCDC88A,DPYSL5,MMD,RGMB,CALM1,HMG20B,TCF7,SCRIB,EPHA1,NFIB,PSMA4,RANBP9,STX3,RASA1,CDK5R1,PTPRF,SEMA4D,TMEM30A,CSF1,MATN2,CLMN,AURKA,PITPNA,NR4A2,GDF11,ARPC2,NDE1,JAK3,SEMA3A,KLF7,EHD1,SPRED1,FOXO6,NF2,PSME2,RPS6KA1,IQGAP1,TP53,ERBB2,PHLDA1,PDGFA,ARTN,CDH1,DACT1,LMO4,FRYL,LHX6,BCL6,TWIST1,DIXDC1,DAB2IP,EPHB4,NOTCH3,ACSL4,DLG3,RASGEF1A,ETV4,SEMA3B,FRS3,SSH3,CAMSAP3,COL6A2,TIMP2,AKT1,FZD4,CDC20,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,NFIX,ARHGAP35,EPHA10,IRS2,JAK1,BHLHB9,PTK7,AXL,SLC9A6,PEX2,SIPA1L1,EFNA5,SPTBN5,NRG1,RGS14,LIFR,COBL,BIN1,CTHRC1,COL9A3,ARHGEF11,ADGRG1,CIT,LRP4,SDC4,PBX3,PSMD10,COL4A5,TGFBR1,CRABP2,PLPPR4,SPR,FGF19,EFNB1,SIX4,NRP2,PPP2R3A,TEAD3,NEO1,HDAC9,KIF5B,IGSF9,PTEN,CDK16,MYCL,BMP7,KIAA0319,BAX,SGK1,ATP8B1,ERBB3,TLE6,S100A6,FARP2,RASGRF1,TGIF1,HES1,B3GNT2,ARHGEF28,RHOA,PSMB4,FMN1,ASPM,RAPGEF2,GRIN1,STMN3,RUNX3,YES1,CDK5RAP1,CNTNAP1,PITX2,FAT4,FGFR2,NR4A3,RYK,PGRMC1,GRIN2D,GPER1,ITGAV,FZD5,SOX8,ARSB,L1CAM,RGMA |
| 3.953e-12 | -26.26 | protein phosphorylation | biological process | GO:0006468 | 942 | 163 | 16441 | 1675 |
CAMKK1,EPHA4,RET,NRG2,PSME1,IL18,CAMK1D,CCNB1,PDGFB,SPTB,GRM5,CALM2,DAPK2,WEE1,PSMD1,RPS6KA2,SHC3,IL31RA,PASK,PIK3CA,DUSP10,PIK3CD,RASGRP1,PLK1,ACVR1C,PBK,ROR1,PRKRA,CDK1,STK17B,ADRBK2,PLK2,LIMK1,NOD2,CAB39,ITPKA,GAB1,PRKAA2,CDK17,LMTK3,NUAK1,RASA2,SOX9,CALM3,ADCK5,TEC,TNFRSF19,MERTK,BMP2K,IGF1R,PPP4R1,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,MDFIC,ALPK1,PIM1,NCAM1,MAST4,MDFI,MMD,TESK1,STAT4,CALM1,STRADB,EIF2AK1,EPHA1,PDK3,ELK1,PDIK1L,PSMA4,CDK5R1,RASA1,STK17A,MAPKAPK2,PRKAG2,CSNK1G1,AURKA,ALPK3,STK39,CDK18,MAP3K5,JAK3,NRBP1,SPRED1,IL15,RPS6KA1,PSME2,ERBB2,TESK2,GRK6,PRKACA,DDR1,PDGFA,CCND1,DOK4,PLK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,F2R,SCYL3,FRS3,MAP3K3,AKT1,RIPK2,PTGER4,PRKCQ,PKMYT1,DUSP4,XRCC6BP1,MAP3K6,EPHA10,IRS2,JAK1,STK26,CDK19,AXL,STK38,PTK7,NRG1,SPTBN5,MLKL,ST3GAL1,MAPK12,PINK1,CIT,PSMD10,TGFBR1,PKN1,TRIB2,FGF19,ADRBK1,CDK16,SGK3,SGK1,BUB1,MAPK11,ERBB3,IQGAP3,SYK,RASGRF1,PSMB4,RAPGEF2,PIK3R1,GRIN1,RUNX3,YES1,FOS,MAPK8IP1,PRDX4,ACVRL1,SCG2,FGFR2,RYK,GRIN2D,ITGAV,LRRK1,HIPK3,MELK |
| 4.445e-12 | -26.14 | cell morphogenesis | biological process | GO:0000902 | 1143 | 189 | 16441 | 1675 |
MYL9,CASP3,EMX1,UGT8,ADD1,SSH1,AK7,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,FAM101B,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,LRRC6,SHC3,DPYSL2,DLG1,TRPC1,NTN4,MYH14,RP2,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,CASP9,EZR,LOXL2,ARHGEF26,DPYSL3,DZIP1L,PLCG1,MAP2,LIMK1,TRAF3IP1,UNC5B,MYL12B,SCN5A,BVES,RASA2,SOX9,RAB23,CALM3,SLC1A3,MERTK,IGF1R,FRY,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,EPB41L5,DPYSL5,RGMB,CALM1,STRADB,SCRIB,EPHA1,NPHP3,ANTXR1,RANBP9,PSMA4,NFIB,RASA1,CDK5R1,ONECUT1,SEMA4D,MATN2,FAM83D,AURKA,PITPNA,NR4A2,ARPC2,CFAP20,JAK3,SHROOM2,SEMA3A,KLF7,EHD1,SPRED1,TCTN2,GRHL2,ST14,PSME2,RPS6KA1,IQGAP1,C5orf30,ERBB2,COL18A1,STIL,TTC21B,PDGFA,SS18,ARTN,FRYL,KIF14,DACT1,BCL6,DAB2IP,EPHB4,RASGEF1A,DLG3,SNX10,ETV4,FRS3,SEMA3B,COL6A2,FZD4,S100A4,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,CEP162,ARHGAP35,EPHA10,IRS2,JAK1,SHROOM3,AXL,SLC9A6,NRG1,EFNA5,SPTBN5,LIFR,COBL,TTC8,COL9A3,PACSIN2,ARHGEF11,FRMD6,POC1B,LRP4,PSMD10,TGFBR1,COL4A5,PLPPR4,SPR,EFNB1,FGF19,NRP2,NEO1,KIF5B,PTEN,BMP7,SGK1,ADAM15,ERBB3,S100A6,FARP2,RASGRF1,HES1,RHOA,B3GNT2,ARHGEF28,PSMB4,CFAP46,FMN1,RAPGEF2,GRIN1,C1GALT1C1,YES1,BBS2,CNTNAP1,FGFR2,SPINT2,PGRMC1,NR4A3,RYK,GRIN2D,ITGAV,CEP41,PLOD3,L1CAM,RGMA |
| 4.449e-12 | -26.14 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 791 | 140 | 17758 | 1761 |
SUN1,SIGIRR,TXN,CAMKK1,IL18,F11R,SLC20A1,LTBP3,PLS3,WEE1,CPNE2,ANKS6,CTGF,ARHGEF37,OSBPL3,KLF3,MITF,SERINC2,DUSP10,CLDN4,MTMR11,TINAGL1,TRAM1,TIPARP,ZNF462,TRIM8,CD55,SERTAD4,NFE2L1,TFAP2C,ARHGDIB,SAV1,MCFD2,ANLN,PTGFRN,RHEB,COL12A1,ABR,ANKRD10,KCNK1,GDE1,ARRDC1,PIK3C2B,F2RL1,LGALS3,DNAJB2,RASA2,SAMD9,SLC1A3,DHRS3,S100A2,ANO1,PRRG4,ITGA3,CYR61,TNFRSF12A,PIM1,C8orf58,NCEH1,MAST4,GAD1,MDFI,SNX7,CYP26B1,PCDH1,ELK3,MFI2,PRSS23,DHX32,STK17A,BCAR3,PTPRF,PRKAG2,ETS2,KBTBD2,YOD1,ATP1B3,LTBP2,MAL2,PLD1,NDE1,KLF7,SPRED1,SLC25A24,CAST,PKP2,PRSS22,IER3,APOBEC3B,ST5,SCNN1A,DACT1,DAB2IP,SULF2,MYO5B,PTPRU,DRAP1,SAT1,C3orf52,SYNE2,RAB38,C15orf39,DOCK5,ALCAM,H2AFV,GABARAPL1,CORO1C,OVOL1,TLE1,PPP2R2D,PRR15,ANXA3,ARHGEF3,TSPAN15,FRMD6,DSE,CRABP2,ETS1,SH2D4A,SGPL1,IRF2BPL,CD109,TMEM87B,GNB5,CALD1,TFAP2A,TAGLN2,CLIP2,SYK,AMOTL2,TGIF1,HES1,NUB1,FURIN,PARP4,COL7A1,PLOD2,ITGAV,PTGES,AHR |
| 4.486e-12 | -26.13 | cell differentiation | biological process | GO:0030154 | 3353 | 452 | 16441 | 1675 |
ADD1,HSPG2,SSH1,LGR4,RET,HEXB,CACNA2D2,NRG2,PSME1,PLXNA1,CAMK1D,CCNB1,FAM101B,NCS1,GRM5,CALM2,CDKN2C,WEE1,TYMP,PSMD1,CYP1A1,CTGF,PAQR5,IL31RA,PIK3CD,SEMA3G,PACSIN1,ZBTB18,TIPARP,TIAM1,SMARCA2,ACVR1C,CASP9,TFAP2C,LOXL2,SAV1,ARF4,ARHGEF26,COL12A1,PGF,PLCG1,HLF,LIMK1,PTER,PLK2,NKD1,BMP1,HDAC1,DHTKD1,TMOD2,UNC5B,ITPKA,ARF6,F2RL1,E2F8,LZTS1,SEMA6B,SCN5A,MRC2,ALDH6A1,CDKN1C,ITGA6,SOX9,MTL5,SLC1A3,GPSM2,HERC6,MERTK,KIAA1161,LMNA,ELF3,MECOM,ITGA3,FRY,CYR61,FLRT3,MEGF8,BHLHE41,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,DGKG,RIMS2,PAQR7,EPB41L5,REC8,MMD,CALM1,ERO1A,AMER1,EPHA1,ELK1,TP53INP2,ANTXR1,NFIB,PSMA4,STX3,RASA1,FAS,PTPRF,MMP15,ETS2,SEMA4D,MATN2,FAM83D,CLMN,AURKA,SFMBT1,NR4A2,GDF11,ARPC2,NDE1,HOOK1,EHD1,SPRED1,FOXO6,SLC2A4,GRHL2,ST14,THRA,IQGAP1,CAST,RPS6KA1,BCL2L1,APC2,PRKACA,TNFSF9,CCND1,NOV,CDH1,DACT1,DAB2IP,EPHB4,ACSL4,PDE4D,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,FOXJ2,HTATIP2,SLC11A2,PRKCQ,RAB38,PYGO1,ALCAM,FZD7,CMTM7,NFIX,EPHA10,IRS2,JAK1,SHROOM3,SLC9A6,AXL,CORO1C,SIPA1L1,KLF5,NRG1,RGS14,COBL,MAPK12,WASF3,CTHRC1,SDC4,PBX3,PLPPR4,SPR,ETS1,EFNB1,FGF19,SIX4,TEAD3,NEO1,SGPL1,E2F7,IGSF9,PTEN,CST3,BAX,CD9,ADAM15,ATP8B1,MAPK11,TAGLN2,ERBB3,CITED2,SGCB,SPRY2,S100A6,OSGIN1,FARP2,RASGRF1,TGIF1,B3GNT2,ARHGEF28,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,FBXO9,C1GALT1C1,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,PITX2,CNTNAP1,ACVRL1,FGFR2,TBX18,NR4A3,RYK,ERAP1,GRIN2D,GPER1,ITGAV,FHL1,LRRK1,FZD5,OSR1,WDR62,ARSB,SLC25A38,JARID2,TLL2,RGMA,EXPH5,MYL9,CASP3,EMX1,UGT8,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,MPP5,DNER,SDC1,PDGFB,CACNB4,TMC1,SPTB,PLS3,EPCAM,RPS6KA2,NPNT,SHC3,DPYSL2,IL6ST,IMPAD1,MITF,ELF5,DLG1,TMEM143,DUSP10,TRPC1,NTN4,CTTN,MYH14,BTBD3,RASGRP1,THRB,ATL1,CELSR2,NFE2L1,EZR,CR2,KLK6,ANLN,ZBTB7B,CDK1,RHEB,DPYSL3,EDNRA,MDK,HS6ST1,GPRC5B,MAP2,MYL12B,MAFF,NR2C2,GRN,RUNX2,LGALS3,SERPINE2,BVES,RASA2,ETV5,CALM3,CNTNAP2,TEC,IL18R1,DAZAP1,IGF1R,GATA2,KIF13B,COL6A1,C10orf54,WNT3A,ETV7,CCDC88A,MDFI,CYP26B1,DPYSL5,ELK3,RGMB,HMG20B,TCF7,SCRIB,EIF2AK1,RANBP9,CDK5R1,FOXD2,FECH,ONECUT1,PVRL2,COL13A1,UTP14C,MFSD2A,ITGA7,TMEM30A,CSF1,PLPP3,EGFL7,PITPNA,TMEM120A,JAK3,SEMA3A,RARG,KLF7,HOXB7,NF2,IL15,FOXM1,PSME2,HDAC11,TP53,COL18A1,ERBB2,TDRKH,OSR2,PHLDA1,PDGFA,ARTN,KIF14,LMO4,FRYL,PLCG2,LHX6,PLK4,BCL6,CDH3,TWIST1,DIXDC1,NOTCH3,SULF2,FRS3,SIRT1,TIMP2,AKT1,FIGNL1,PTPRU,OSTM1,S100A4,CDC20,PTGER4,GLO1,MYL12A,DAG1,SOCS3,ARHGAP35,PTPRJ,BFSP1,BHLHB9,PTK7,PEX2,PTBP3,EFNA5,SPTBN5,LTA4H,LIFR,BIN1,COL9A3,SORT1,ARHGEF11,CD63,ADGRG1,CIT,FRMD6,LRP4,PSMD10,COL4A5,GDF15,TGFBR1,CRABP2,NRP2,PPP2R3A,HDAC9,TOP2A,CD109,KIF5B,LLGL2,CDK16,MYCL,BMP7,RRBP1,KIAA0319,TFAP2A,UBE2J1,SGK1,SYK,TLE6,MYO5A,HES1,RHOA,PSMB4,ASPM,NR4A1,RC3H2,STMN3,RUNX3,COL7A1,FNDC3A,BBS2,FOXL1,ARHGAP24,FAT4,TWSG1,DHRS2,CTSV,SPINT2,RAP2C,PGRMC1,HOXB13,PLOD3,ZMIZ1,SOX8,L1CAM |
| 4.545e-12 | -26.12 | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 363 | 80 | 17758 | 1761 |
MYL9,DLGAP5,PTTG1,PDIA5,ERBB2,COL18A1,NDRG2,CCNB1,EMP2,MNS1,CENPN,SH3KBP1,APOBEC3B,CDKN2C,KIF14,PLK4,CLDN4,PLK1,CENPA,TIMP2,S100A4,CDCA2,LOXL2,PPP1R14C,CDK1,DAG1,RBL1,PIK3C2B,RELL1,PRSS8,DEPDC1,ENO2,CIT,BLVRB,CDCA8,SELL,KIF23,SLC36A4,SLC1A3,NRP2,IL17RB,TOP2A,CA2,CYR61,PIK3AP1,VASN,NEK2,SLC44A2,ADAM15,BUB1,TAGLN2,KLF9,ERBB3,SLC12A2,MPHOSPH9,AMOTL2,SUN2,ZWINT,PSMB4,NR4A1,SPATA13,MYBL2,NEURL1B,KIF11,PITX2,TJP3,H1F0,PVRL2,DBI,FAM83D,AURKA,SFMBT1,CTSA,CENPE,GEM,NCAPG2,UBE2C,CCNB2,ACOT7,MELK |
| 4.640e-12 | -26.10 | cell projection organization | biological process | GO:0030030 | 1206 | 197 | 16441 | 1675 |
MYL9,EMX1,UGT8,AK7,CUL4B,EPHA4,ARFGEF1,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,RPS6KA2,PSMD1,LRRC6,SHC3,DPYSL2,DLG1,TRPC1,NTN4,CTTN,MYH14,PACSIN1,TIAM1,BTBD3,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,EZR,ARF4,ARHGEF26,DZIP1L,DPYSL3,PLCG1,MAP2,LIMK1,TRAF3IP1,UNC5B,ITPKA,ARF6,MYL12B,FGD1,PIFO,SCN5A,ITGA6,RASA2,RAB23,CALM3,CNTNAP2,NCKAP1,ITGA3,IGF1R,FRY,MEGF8,FLRT3,COL6A1,PRKG1,FXYD5,CACNA1D,NCAM1,WNT3A,NUP85,CCDC88A,DPYSL5,RGMB,CALM1,ANO6,SPATA13,SCRIB,EPHA1,NPHP3,NUBP1,PSMA4,RANBP9,NFIB,STX3,RASA1,CDK5R1,PTPRF,ONECUT1,PVRL2,SEMA4D,MATN2,FGD6,CLMN,AURKA,PITPNA,NR4A2,CFAP20,ARPC2,SEMA3A,JAK3,KLF7,EHD1,SPRED1,TCTN2,RPS6KA1,IQGAP1,PSME2,C5orf30,ERBB2,STIL,EMP2,MNS1,PDGFA,TTC21B,CDH1,ARTN,DACT1,FRYL,DAB2IP,ACSL4,EPHB4,DLG3,RASGEF1A,ETV4,SNX10,FRS3,SEMA3B,CAMSAP3,COL6A2,AKT1,PRKCQ,SLC11A2,ALCAM,DAG1,MYL12A,ARHGAP35,CEP162,EPHA10,IRS2,JAK1,STK26,SLC9A6,SPTBN5,NRG1,EFNA5,KLF5,COBL,LIFR,TTC8,WASF3,COL9A3,CTHRC1,PACSIN2,ARHGEF11,POC1B,CIT,LRP4,SDC4,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,NEO1,KIF5B,IGSF9,CDK16,PTEN,BMP7,SGK1,ERBB3,S100A6,FARP2,RASGRF1,B3GNT2,ARHGEF28,LCA5,RHOA,PSMB4,CFAP46,FMN1,RAPGEF2,GRIN1,STMN3,YES1,BBS2,CNTNAP1,FAT4,FGFR2,RAP2C,PGRMC1,NR4A3,RYK,GRIN2D,ITGAV,CEP41,L1CAM,ARHGEF4,RGMA |
| 5.134e-12 | -26.00 | cellular component morphogenesis | biological process | GO:0032989 | 1223 | 199 | 16441 | 1675 |
MYL9,CASP3,EMX1,UGT8,ADD1,SSH1,AK7,EPHA4,NRG2,MPP5,PSME1,PLXNA1,CACNB4,FAM101B,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,LRRC6,SHC3,DPYSL2,DLG1,TRPC1,NTN4,MYH14,RP2,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,CASP9,EZR,LOXL2,ARHGEF26,DPYSL3,DZIP1L,PLCG1,MAP2,DNM1L,LIMK1,TRAF3IP1,TMOD2,UNC5B,MYL12B,SCN5A,BVES,RASA2,SOX9,RAB23,CALM3,SLC1A3,MERTK,IGF1R,FRY,FLRT3,COL6A1,CACNA1D,PIKFYVE,NCAM1,WNT3A,EPB41L5,DPYSL5,RGMB,CALM1,STRADB,SCRIB,EPHA1,NPHP3,ANTXR1,RANBP9,PSMA4,NFIB,RASA1,CDK5R1,ONECUT1,PVRL2,SEMA4D,MATN2,FAM83D,AURKA,PITPNA,NR4A2,ARPC2,CFAP20,JAK3,SHROOM2,SEMA3A,KLF7,EHD1,SPRED1,MTM1,TCTN2,GRHL2,ST14,PSME2,IQGAP1,RPS6KA1,C5orf30,ERBB2,COL18A1,BCL2L1,STIL,PDGFA,TTC21B,SS18,ARTN,FRYL,KIF14,DACT1,BCL6,DAB2IP,EPHB4,RASGEF1A,DLG3,SNX10,ETV4,FRS3,SEMA3B,COL6A2,FZD4,S100A4,PRKCQ,SLC11A2,ALCAM,MYL12A,DAG1,FZD7,CEP162,ARHGAP35,EPHA10,IRS2,JAK1,SHROOM3,AXL,SLC9A6,NRG1,EFNA5,SPTBN5,LIFR,COBL,TTC8,COL9A3,PACSIN2,ARHGEF11,FRMD6,POC1B,LRP4,PSMD10,TGFBR1,COL4A5,PLPPR4,SPR,FGF19,EFNB1,SIX4,NRP2,NEO1,KIF5B,PTEN,BMP7,BAX,CD9,ADAM15,SGK1,ERBB3,S100A6,FARP2,RASGRF1,HES1,RHOA,B3GNT2,ARHGEF28,PSMB4,FMN1,CFAP46,RAPGEF2,GRIN1,C1GALT1C1,YES1,BBS2,CNTNAP1,FGFR2,SPINT2,PGRMC1,NR4A3,RYK,GRIN2D,ITGAV,CEP41,PLOD3,L1CAM,RGMA |
| 6.225e-12 | -25.80 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 11169 | 1233 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,CARD10,LTBP3,ZNF275,CDKN2C,PAQR5,TMEM37,TIAM1,TIPARP,MGAT5,CDA,TMEM151A,PRKAR2B,ABR,ARF4,ENPP1,PLCG1,CARHSP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,FAM21C,TTYH3,MARCH8,TFAP4,FRY,RIMS3,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,HPS3,PQLC3,NPHP3,PCTP,SFXN5,GNA11,PSMA4,CACHD1,ETS2,S100A5,CLMN,TMEM173,DOCK9,NQO1,PTTG1,MGST2,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,PTPN9,SEPT6,SAT1,XRCC6BP1,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,HABP4,SDC4,OSGIN2,BTN3A1,SLC25A43,CTNNBIP1,ITGB8,MGAT4A,FAM20B,BAX,FAM102A,IGFBP2,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,AK4,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,PLS3,SUSD2,CPNE2,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,THRB,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,ZNF367,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,RASA2,PDCL,ADCK5,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,AHCY,FAR2,WNT3A,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,CDK5R1,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,EFNA5,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,HAL,CDCA8,GTF3A,GDF15,LBR,AIP,PARM1,VPS26A,NRP2,SH2D4A,FZD6,ZDHHC21,CD109,C16orf74,LYPD6,GTF2F2,FAM63A,SGK1,TSPAN13,ALDH7A1,ATP2B1,NFE2L3,FBLN5,MOSPD2,GUSB,PLAUR,MAML2,GGH,RNPEP,BBS2,TXNDC11,DGKE,SH3BGRL2,PTGES,HIPK3,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,HSPG2,SSH1,VANGL1,TSC22D3,NANS,VASH1,OAT,PJA2,SLC9A7,ANKS6,STIM1,OSBPL3,PIK3CA,SNX16,IRF2,ACVR1C,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TNFRSF19,MESDC2,DOPEY2,RALGPS2,ZNRF2,AIM1,DAPK1,TMEM51,PRKG1,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,LPGAT1,CALM1,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,FAM83D,AGBL5,SFMBT1,CABIN1,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,THRA,RALBP1,ATP2C2,BCL2L1,TMEM170B,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,BRI3,EPHB4,PDE4D,MED30,NAGA,COG2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TSPAN18,ZNF704,FAM195A,COBL,CBX7,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,FGF19,SLC25A36,WWP2,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,TBX18,ABCB1,ERAP1,WDR62,ESPL1,MELK,DEF6,RGMA,UGT8,CRYM,MPP5,ERP29,TRIM68,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,ANKFN1,TRPC1,MYRIP,BTBD3,LAMP3,CENPA,USP18,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,MADD,ZNF165,SP6,CAPN1,NR2C2,CD99,LASP1,ARAP3,PPP1R2,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,PM20D2,FAM81A,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,APOL2,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,KCTD9,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,PTPRU,GLO1,CD40,CASP4,SOCS3,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,HMGXB4,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,TCEAL8,ARHGAP24,ENDOD1,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,TINAGL1,PIK3CD,ACOX2,ERAP2,NWD1,TNIP1,SH3BGRL,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,MRPS28,RELL1,ARF6,E2F8,GAB1,FAM169A,ALDH6A1,SOX9,MERTK,LMNA,RAVER2,GNS,FAM189A1,FAM13B,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,AURKA,FBXO27,ARPC2,DRP2,NDE1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,IL13RA1,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,CAMSAP3,FZD4,PLEKHO1,SYNE2,CYS1,NUSAP1,CDCA2,RAB38,IRS2,SIPA1L1,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,TIPRL,SRPX2,NEO1,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,CALD1,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,GALNT3,NR1D2,CENPE,USF2,CYBRD1,DCBLD1,SIGIRR,GNPDA1,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,NDC80,HDAC6,NUP62CL,SDC1,SHC3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,ZCCHC24,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,TESK1,CORO2A,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,PVRL2,PRPS2,LTBP2,ATP1B3,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,CCDC68,LPIN3,RAD23A,ATP6V0B,EFR3A,MINPP1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,CDC20,DUOX1,DNAJC10,PRRT4,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,CMTM4,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,RUSC2,DAP,BLVRB,GABRG2,DSE,CRABP2,SIRPA,SLC9A2,PPP2R3A,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,CRB3,NR3C1,AMFR,LITAF,PPARA,FNDC3A,BSDC1,MAPK8IP1,PRDX4,CD83,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NMI,NETO2,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,NDFIP1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,PLXNA1,SLC20A1,NCS1,SESN3,ELMO2,PRICKLE3,IQCE,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,RCAN3,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,SPNS3,ARHGEF26,AHRR,SLC25A4,GNPTAB,PTER,NKD1,FAM110C,DHTKD1,EIF4EBP2,UNC5B,TANC2,TRAF5,DDX58,CDK17,FRMD4A,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,PRRG4,MECOM,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,EPB41L5,FADS2,DDB2,PMPCB,MFI2,TBC1D8B,MICB,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,NLRX1,TRIP10,CAST,IQGAP1,RPS6KA1,BROX,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,IFIT1,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,CCNJL,SEPP1,LGALS3BP,TMCC3,SNTA1,PHF7,PTEN,ATP8B1,SLC44A2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,AMMECR1,CCDC69,CSTF2,PGM2L1,GRIN2D,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,CPT2,HEBP1,DNER,CACNB4,KREMEN1,DENND2D,TMC1,TSEN34,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,LRRC6,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,POF1B,SUN3,RAB20,RP2,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,ARHGEF19,NEIL1,ZNF114,ADIPOR1,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,NCEH1,SIMC1,LRIF1,KDELR1,OXR1,HMG20B,AMDHD1,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,PROM2,SPC25,FAM92A1,IL15,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,F2R,PDIA6,FRS3,SUSD3,GCA,ZNF525,SLC39A8,OSTM1,DUSP4,DOCK5,KCTD2,BFSP1,OVOL1,VSIG10,CYP2U1,REEP4,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,DEPDC4,MBNL3,LRRC66,OGDHL,KLHL2,C2orf70,HNRNPH2,OTUB2,GEM,SNPH |
| 6.368e-12 | -25.78 | GSE7460_TCONV_VS_TREG_LN_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_DN | 196 | 53 | 17758 | 1761 |
TTC8,CCNE2,KIAA1462,NFKBIE,ATP9A,FRMD6,UBASH3B,TGFBR1,CD274,BCL2L1,NCKAP1,PHLPP1,HDAC6,BMP2K,HDAC9,IGF1R,SNX18,OSBPL3,ZDHHC23,MDFIC,TMEM64,LMAN1,SLC12A2,F2R,MGAT5,SOCS5,ELK3,SH3BGRL,CORO2A,PTGER4,PRICKLE1,KIF13A,DUSP4,PRKRA,SESN1,CASP4,CD83,GABARAPL1,PIAS3,BANK1,ACADSB,TWSG1,AXL,MATN2,LRIG1,ABCB1,SH3BGRL2,NFKBIZ,GEM,TANC2,TBC1D4,AHR,RRAGD |
| 6.400e-12 | -25.77 | positive regulation of catalytic activity | biological process | GO:0043085 | 1521 | 236 | 16441 | 1675 |
CASP3,TXN,CAMKK1,EPHA4,RET,ARFGEF1,NRG2,DNAJB11,F11R,PSME1,ITPR2,CCNB1,PDGFB,ERP29,CARD10,DENND2D,SPTB,GRM5,CALM2,ARHGEF10L,SIPA1L2,PSMD1,CTGF,NPNT,SHC3,ARHGEF37,RGS3,SERINC2,PIK3CA,DLG1,RP2,SLC39A10,TIAM1,RASGRP1,PLK1,ACVR1C,CASP9,ARHGDIB,PRKAR2B,PRKRA,CDK1,POR,ARF4,ABR,ARHGEF26,EDNRA,PLEKHG6,PLCG1,MID1IP1,ARHGEF19,GPRC5B,MADD,NOD2,AGFG2,CAB39,RAP1GAP,GAB1,FGD1,PIFO,ARAP3,TBC1D1,ITGA6,RASA2,CALM3,FBLN1,TFAP4,RALGPS2,CYR61,SNX18,RINL,TBCD,RANBP1,FAM13B,NEK2,DAPK1,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,PLCB2,ALS2CL,CCDC88A,GPR161,MDFI,MMD,TBC1D8B,CALM1,SPATA13,PDE5A,STRADB,SCRIB,EPHA1,PSMA4,PLIN5,RASA1,CDK5R1,FAS,RASGRP2,GNAS,MMP15,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,CSF1,ITPR1,FGD6,NR4A2,STK39,CTSA,ATP1B3,MAP3K5,JAK3,XDH,DOCK9,ARHGAP11A,SPRED1,AVPI1,GRHL2,IQGAP1,PSME2,RALBP1,RGS20,ERBB2,MGST2,PRKACA,EMP2,STIL,BCAP31,ARHGEF16,EPS8L2,CCND1,PDGFA,ST5,ACAP2,SH3BP1,KIF14,CDKN1B,CDH3,DAB2IP,RASGEF1A,EGLN3,F2R,GM2A,DVL2,FRS3,MAP3K3,DOCK4,SIRT1,TIMP2,RIPK2,AKT1,FZD4,CDC20,PRKCQ,SLC11A2,ATP1B1,ITPR3,CD40,DOCK5,MAP3K6,ARHGAP35,IRS2,DNAJC10,JAK1,STK26,NGFRAP1,MMP17,WFS1,CORO1C,SIPA1L1,PLEKHG1,SLC27A1,EFNA5,SPTBN5,NRG1,RGS14,DENND5B,MAPK12,ARFGEF3,GCLM,ARHGEF3,PINK1,PCOLCE,NKX3-1,DEPDC1,ARHGEF11,DAP,SDC4,PSMD10,TGFBR1,PKN1,SBF1,ARHGEF40,FGF19,PARM1,CARD8,ADORA1,ADRBK1,CTSC,LLGL2,PTEN,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,FARP2,PDGFC,RASGRF1,ARAP2,RHOA,ARHGEF28,PLSCR1,PSMB4,RAPGEF2,GRIN1,RGCC,GRTP1,GPLD1,ARHGAP24,FGFR2,ARRB1,PPP2R3C,GRIN2D,GPER1,CENPE,FZD5,TBC1D4,UBE2C,ARHGEF9,RAB3IL1,ARHGEF4 |
| 6.505e-12 | -25.76 | FEVR_CTNNB1_TARGETS_UP | MSigDB lists | FEVR_CTNNB1_TARGETS_UP | 646 | 120 | 17758 | 1761 |
CASP3,MTM1,ACACB,CCDC109B,TTC39B,UGP2,IL15,GNPDA1,ATP8A1,ATP2C2,TAP1,C5orf30,F11R,IL13RA1,TGOLN2,SLC20A1,EPS8L2,SYTL2,CDS1,TYMP,CTGF,ELMO2,FABP6,PLCG2,KLF3,BCL6,SRR,VAT1,GOT1,RAB20,CRY2,CTTN,EGLN3,DLG3,PTPRE,SULT2B1,TRIM8,KIFC2,USP18,CASP9,SYNE2,GLO1,SLC11A2,KLK6,MCFD2,DOCK5,CASP4,STK17B,POR,ABR,SOCS3,OPTN,GABARAPL1,TMEM164,HLF,CORO1C,WFS1,FAM114A1,TRIOBP,PLEKHG1,IRF7,CYP2U1,UNC5B,ITPKA,MAFF,PCSK5,LGALS3,GGA1,HLA-E,DNAJB2,DAP,EPS8,HAL,RAB6A,NUCB2,LMNA,NRP2,PARM1,SGPL1,AIM1L,CXCL16,ADRBK1,MLPH,ITGA3,IGSF9,RRBP1,TNFRSF12A,ABCD1,CACNA1D,PIM1,OSGIN1,S100A6,GCNT1,OPLAH,KLK5,GCLC,CORO2A,LITAF,EIF2AK1,EPHA1,IFIT3,FOS,GNA11,STX3,MMP15,SLC6A6,FAAH,SYT7,CGREF1,TMC5,ABCB1,CLMN,CDK18,CMPK2,TMEM120A,SERPINB1,NDFIP1,OCLN,KLF7,XDH |
| 6.522e-12 | -25.76 | bile_duct | COSMIC cancer mutations | bile_duct | 15891 | 1649 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,NEK2,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.522e-12 | -25.76 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15891 | 1649 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,NEK2,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.959e-12 | -25.69 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 632 | 118 | 17758 | 1761 |
UNKL,LTBP1,GAA,SSH1,HSPG2,IQGAP1,TMEM41B,PDIA5,ERBB2,TEX2,PLXNA1,SDC1,DDR1,SLC20A1,TNFSF9,LTBP3,CMTM6,BCAP31,CHPF,APLP2,ATP6V0B,PQLC2,IL6ST,TSPAN6,ZFP36,TINAGL1,MANF,ECE1,EPHB4,SLC39A10,MINPP1,LMAN1,RNF26,PDIA6,CPD,PLK1,TIMP2,CDC20,SLC11A2,IGSF8,PKMYT1,ICMT,ITPR3,ATP10D,POR,DAG1,FZD7,ATP1A1,GPRC5B,DDOST,ABHD12,AXL,SLC9A6,P4HA2,BMP1,PIEZO1,GLA,GRN,MRC2,TM2D2,PCOLCE,IGFBP6,PDIA3,COL4A5,CTSZ,SBF1,EFNB1,NRP2,NEO1,PDIA4,TMEM63A,SGPL1,M6PR,GNS,CD109,ITGA3,IGF1R,VASN,KCNN4,CST3,DRAM1,CD9,SLC44A2,TMBIM6,TNFRSF12A,NCAM1,CNPY3,CRTAP,CKAP4,ABCC1,HMMR,AMOTL2,B3GALT6,PCDH1,PRSS23,RGMB,GUSB,ANO6,TTC7A,SPTLC2,TXNDC11,NFIB,PRDX4,PTPRF,ENDOD1,RPL12,FAM64A,PVRL2,CSF1,FAM83D,PCDH19,LTBP2,PLOD3,WDR62,PTGES,DCBLD1,TMEM173,ESYT2 |
| 7.222e-12 | -25.65 | HAN_SATB1_TARGETS_DN | MSigDB lists | HAN_SATB1_TARGETS_DN | 420 | 88 | 17758 | 1761 |
MYL9,LTBP1,LZTFL1,PAPSS2,HOXB7,EPAS1,CD82,TAP1,IL18,AIFM2,AP1M2,RPS6KA2,CDH1,PHTF1,MITF,CDH3,PIK3CD,PDE4D,OAS3,PTPRE,NAGA,CPD,MX1,MBP,COL6A2,FZD4,OSTM1,SEPT6,TFAP2C,TNS1,CD40,TP53I3,CASP4,ATP13A2,LRRC42,C19orf66,RAB11FIP1,KLF5,PPP2R2D,MAFF,DENND5B,PCSK5,WASF3,PACSIN2,ENO2,ZCCHC24,CTSZ,COL4A5,SBF1,IL18R1,DNAJB9,SGPL1,M6PR,NEO1,B3GALNT1,TAF1B,CALD1,ALG13,SORL1,LIMCH1,MAPK11,CITED2,ULBP2,TPCN1,RIMS2,CYP26B1,RASGRF1,NR3C1,RC3H2,AK4,IFIT3,ANTXR1,STX3,PTPRF,NCOA3,PRKAG2,RAB11FIP2,PLOD2,RND3,PELI2,MATN2,SLC2A6,ITPR1,FHL1,JAK3,APOL2,RARG,KLF7 |
| 7.851e-12 | -25.57 | biliary_tract | COSMIC cancer mutations | biliary_tract | 16126 | 1667 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.060e-11 | -25.27 | positive regulation of molecular function | biological process | GO:0044093 | 1782 | 267 | 16441 | 1675 |
TXN,ADD1,RET,NRG2,PSME1,CAMK1D,CCNB1,CARD10,GRM5,CALM2,PSMD1,CTGF,STIM1,RGS3,SERINC2,PIK3CA,TIAM1,ACVR1C,CASP9,PRKAR2B,SAV1,POR,ARF4,ABR,ARHGEF26,PLCG1,MID1IP1,PLK2,NOD2,AGFG2,TRAF5,GAB1,FGD1,DDX58,TBC1D1,ITGA6,TFAP4,RALGPS2,CYR61,SNX18,RANBP1,FAM13B,NEK2,DAPK1,MAP3K9,SORL1,NCAM1,GPR161,EPB41L5,MMD,TBC1D8B,CALM1,EPHA1,PSMA4,PLIN5,RASA1,FAS,MMP15,NCOA3,PRKAG2,SEMA4D,ITPR1,FGD6,NR4A2,STK39,MAP3K5,TMEM173,XDH,DOCK9,ARHGAP11A,SPRED1,GRHL2,IQGAP1,RALBP1,RGS20,MGST2,PRKACA,EPS8L2,CCND1,ST5,ACAP2,SP100,SH3BP1,CDKN1B,DAB2IP,RASGEF1A,DOCK4,RIPK2,FZD4,PRKCQ,SLC11A2,ATP1B1,ITPR3,GTF2A2,IRS2,JAK1,NGFRAP1,STK26,WFS1,CORO1C,SIPA1L1,PLEKHG1,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,TCAF1,CTHRC1,ARHGEF3,PCOLCE,NKX3-1,DEPDC1,SDC4,PKN1,ARHGEF40,FGF19,CTSC,PTEN,SGK3,BAX,MAPK11,ERBB3,TRIM62,SPRY2,NCOA2,FARP2,PDGFC,RASGRF1,ARAP2,ARHGEF28,PLSCR1,RAPGEF2,GRIN1,GRTP1,GPLD1,FGFR2,GRIN2D,GPER1,CENPE,FZD5,CASP3,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,ERP29,PDGFB,SPTB,DENND2D,ARHGEF10L,SIPA1L2,ARHGEF37,SHC3,NPNT,DLG1,RP2,SLC39A10,RASGRP1,PLK1,TRIM8,ARHGDIB,PRKRA,CDK1,EDNRA,KDM4D,PLEKHG6,ARHGEF19,GPRC5B,MADD,CAB39,RAP1GAP,PIFO,ARAP3,RASA2,CALM3,FBLN1,RINL,TBCD,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,CCDC88A,MDFI,SPATA13,STRADB,PDE5A,SCRIB,CDK5R1,RASGRP2,BCAR3,MAPKAPK2,GNAS,CSF1,PLPP3,NFKBIA,CTSA,ATP1B3,JAK3,AVPI1,PSME2,ERBB2,STIL,EMP2,BCAP31,ARHGEF16,PDGFA,KIF14,PLCG2,CDH3,TWIST1,EGLN3,F2R,GM2A,DVL2,CTH,CHP1,FRS3,SIRT1,MAP3K3,TIMP2,AKT1,CDC20,CD40,DOCK5,MAP3K6,ARHGAP35,DNAJC10,MMP17,SPTBN5,EFNA5,ARFGEF3,GCLM,ANXA3,PINK1,ARHGEF11,DAP,PSMD10,TGFBR1,SBF1,PARM1,CARD8,ADRBK1,ADORA1,LLGL2,TRIM21,SGK1,IQGAP3,SYK,HES1,RHOA,PSMB4,PLAUR,AMFR,RGCC,ARHGAP24,ARRB1,PPP2R3C,UBE2C,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4 |
| 1.168e-11 | -25.17 | GSE10325_BCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_BCELL_VS_LUPUS_BCELL_DN | 193 | 52 | 17758 | 1761 |
DLGAP5,LGALS3,PSME2,HLA-E,DNAJC3,TAP1,PDIA5,CDCA8,HERC5,NDUFA4,HMGN3,PSME1,RAB6A,HERC6,PJA2,SDC1,HLA-A,BTG3,CTSC,IFIT1,ACSL4,OAS3,TIPARP,TRAM1,APOBEC3G,NAGA,HMMR,REC8,PPIF,GFPT1,LAMP2,MX1,PLSCR1,USP18,ITCH,RAPGEF2,MICB,SAT1,GGH,BLVRA,IFIT3,KIF11,OPTN,FAS,BCAR3,DDOST,RBM47,TMEM30A,NMI,IRF7,ZMIZ1,IFI6 |
| 1.220e-11 | -25.13 | negative regulation of biological process | biological process | GO:0048519 | 4447 | 571 | 16441 | 1675 |
HECA,ACACB,ADD1,DNAJC3,FBXO2,IL18,MORF4L2,SYTL4,BARD1,GRM5,CALM2,CDKN2C,PSMD1,CABP1,CRY2,SEMA3G,TIPARP,APOBEC3G,SMARCA2,TNIP1,CDA,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,ARF4,ABR,PIAS3,ENPP1,MID1IP1,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,ARF6,HSPB1,E2F8,NFKBIE,NUAK1,ITGA6,SOX9,RAB23,FAM21C,MERTK,LMNA,ELF3,MARCH8,TFAP4,PAIP2B,NEK2,MYDGF,MYLIP,NUP85,SALL4,ERO1A,NPHP3,TP53INP2,PSMA4,PLIN5,NCOA3,ETS2,SEMA4D,ITPR1,AURKA,CLMN,STK39,GDF11,SERPINB1,NUP58,XDH,EGLN1,GRHL2,NQO1,INPP5D,PTTG1,RGS20,PKP2,PRKACA,APC2,CCND1,CDH1,SP100,DACT1,ACSL4,DLG3,CDKN2D,MYT1,ETV4,MX1,CAMSAP3,RIPK2,APOBEC3D,FZD4,HTATIP2,SNX12,NFIX,IRS2,CORO1C,WFS1,AXL,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TCAF1,TNRC6C,NKX3-1,CKAP2,ANO9,PKN1,ETS1,GSTP1,TIPRL,NEO1,CTNNBIP1,ITGB8,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,CRTAP,PLSCR1,RAPGEF2,PIK3R1,GRIN1,PITX2,NR1D2,ACVRL1,NR4A3,ITGAV,HMGA1,FHL1,OSR1,SIGIRR,CNOT8,EPHA4,ARFGEF1,LMCD1,NDRG2,F11R,NENF,TP53I11,HDAC6,PDGFB,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,IL6ST,ELF5,PASK,MITF,DUSP10,MYBL1,PLK1,THRB,CD55,KCNIP3,ING1,CBX6,EZR,PRKRA,SESN1,CDK1,RHEB,OPTN,DPYSL3,TRIM9,KLF12,HOXA9,RAB11FIP1,PRKCDBP,KLF11,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,LGALS3,DNAJB2,RASA2,UBASH3B,PDCL,HES2,DHRS3,FBLN1,IGF1R,GATA2,TBCD,MDFIC,PIM1,WNT3A,CYP26B1,STRADB,SCRIB,EIF2AK1,IFIT3,G2E3,CDK5R1,NLRC5,SEMA3A,IFI6,NF2,FOXM1,P3H2,CTDSPL,TP53,ERBB2,STIL,CYP26A1,SYTL2,IER3,PDGFA,LMO4,PLCG2,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,DVL2,CTH,SULF2,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,PTGER4,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,RBL1,STK38,IRF7,ARFGEF3,PINK1,PACSIN2,CPEB4,ADGRG1,DAP,PSMD10,NKRF,AIP,PPP2R3A,FZD6,SH2D4A,CD109,FOXP2,TFAP2A,UBE2J1,TRIM21,BUB1,KLF9,FAIM,NFE2L3,HES1,RHOA,PSMB4,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,PELI3,BBS2,MAPK8IP1,CD83,PRDX4,BANK1,SERPINA1,TWSG1,SCG2,NMI,NDFIP1,TBC1D4,UBE2C,PTGES,HIPK3,ZBTB33,PKIA,PPP4R4,TXN,LGR4,TSC22D3,TAP1,PSME1,CAMK1D,VASH1,CCNB1,FAM101B,CTGF,RGS3,ZFP36,FOSB,IL31RA,PIK3CA,IRF2,TACSTD2,PACSIN1,ZBTB18,ACVR1C,PBK,SLC35C1,AGO4,PIF1,SAV1,CCNF,SLC25A5,POR,AHRR,SLC25A4,PLK2,NKD1,PRDM5,SERPINI1,EIF4EBP2,UNC5B,F2RL1,LZTS1,DDX58,SEMA6B,CDKN1C,HLA-E,SLC25A27,MECOM,ITGA3,CYR61,PIK3AP1,VASN,BHLHE41,PRKG1,DAPK1,SORL1,GPR161,SOCS5,EPB41L5,MFI2,MICB,CALM1,AMER1,EPHA1,NFIB,RASA1,FAS,AP1AR,PRKAG2,PLEKHH2,SFMBT1,CABIN1,NR4A2,PER3,IFIH1,SPRED1,S100A11,NLRX1,THRA,IQGAP1,CAST,DDIT4L,RPS6KA1,FTH1,CD274,BCL2L1,ZFYVE9,APOBEC3B,APLP2,NOV,CDKN1B,DAB2IP,IFIT1,PDE4D,LGMN,NR2C1,SEMA3B,DOCK4,DRAP1,PRKCQ,PKMYT1,RAD17,H2AFV,FZD7,PPP2R5A,TRIOBP,SLC27A1,NRG1,KLF5,CBX7,IGFBP6,DEPDC1,EPS8,HERC5,APOBEC3H,FGF19,HLA-A,ADGRB2,SIX4,WWP2,SNTA1,FAM111A,E2F7,GNB5,RNF128,PTEN,CD9,ATP8B1,ERBB3,CNOT6L,CITED2,SPRY2,TRIM62,OSGIN1,NCOA2,TGIF1,ZWINT,FURIN,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,LRRK1,GPER1,FZD5,ESPL1,CPEB2,JARID2,CASP3,LTBP1,CRYM,ERP29,SH3KBP1,EPCAM,TSPAN6,SIVA1,DLG1,CTTN,SLC39A10,PTPRE,CYP1B1,TRIM8,ITCH,ARHGDIB,EDNRA,CXXC4,MDK,NEIL1,MADD,CAB39,ADIPOR1,GLA,RAP1GAP,ARAP3,SERPINE2,PPP1R2,CALM3,PHLPP1,FXYD5,C10orf54,RFX5,ETV7,MDFI,ELK3,OXR1,HMG20B,PDE5A,NUBP1,RANBP9,GNAS,ONECUT1,NUDT16,PLPP3,CGREF1,NFKBIA,SH3BP4,YOD1,EGFL7,SHROOM2,JAK3,RARG,TOB1,PROM2,GAS2L1,LZTFL1,IL15,PSME2,COL18A1,TDRKH,IL27RA,OSR2,SVBP,SETDB2,KIF14,FABP6,TWIST1,DIXDC1,F2R,CHP1,PTPRU,GLO1,ERBB2IP,DUSP4,DOCK5,SOCS3,ARHGAP35,JADE1,BHLHB9,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,LIFR,ABCA1,GLIS3,GCLM,ANXA3,SORT1,CIT,LRP4,AES,TGFBR1,NOTUM,TRIB2,HMGXB4,HDAC9,TOP2A,IRF2BPL,CARD8,TAF1B,ADRBK1,ADORA1,BMP7,KIAA0319,IQGAP3,NR4A1,GCLC,ASPM,RGCC,MBNL3,RUNX3,LEPR,ARHGAP24,HLA-B,SWAP70,DHRS2,CTSV,RAP2C,SPINT2,ARRB1,SOX8,AHR,CD33,ABCG1 |
| 1.314e-11 | -25.06 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | 279 | 66 | 17758 | 1761 |
KIAA1462,THRA,ERBB2,METTL7A,DPYSL2,PLCG2,ABCA2,GLB1L2,EPHB4,MARCH2,NOTCH3,MGAT5,CTDSP2,NAGA,GM2A,CELSR2,HSPA12A,CBX6,ITPR3,IDH1,H2AFV,POR,DAG1,ABR,ARHGAP35,LRRC42,ALDH5A1,PTK7,WFS1,ATP7B,FAM114A1,PNPLA6,ST3GAL1,CAPN1,LASP1,SERPINE2,ENO2,ITGA6,ZCCHC24,LRP4,SBF1,TMEM63A,PDIA4,GNS,DOPEY2,RIMS3,TBCD,RRBP1,BDH1,CD9,SORL1,NPTXR,IGSF3,DDB2,FADS2,SHMT1,PARP4,FBXO9,TCF7,STEAP1,FUCA1,PTPRF,ITGA7,ITPR1,PITPNA,CTSA |
| 1.531e-11 | -24.90 | GNF2_CENPE | MSigDB lists | GNF2_CENPE | 40 | 21 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,MYBL2,CDCA8,NUSAP1,CCNF,KIF11,CDK1,PRIM1,AURKA,BUB1,CENPE,CCNB2,UBE2C,ESPL1,CKS2 |
| 1.634e-11 | -24.84 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 392 | 83 | 17758 | 1761 |
LAMP1,SIGIRR,NQO1,TMX4,HEXB,PDIA5,IL18,FTH1,TEX2,BCAP31,TSEN34,CCND1,ZFYVE16,APLP2,MITF,AKR1B1,VAT1,RAB20,SNX10,GM2A,CYP1B1,LAMP2,CPD,PPIF,DOCK4,TIMP2,CD55,MCTP1,ACO1,SLC11A2,LHFPL2,MAN2A2,RBM47,GLA,LTA4H,ST3GAL1,GCLM,PINK1,PACSIN2,LGALS3,CDKN1C,ZNF395,TBC1D1,CD63,HLA-E,C6orf106,ASAH1,SELL,GTF3A,SLC1A3,ARHGEF40,HDAC9,GNS,TNS3,MDM1,SLC16A6,BHLHE41,TPST1,TMEM51,CD9,SGK1,TMBIM6,KLF9,CNPY3,ALDH3A2,FAH,WBP5,SUN2,PLSCR1,GGH,SNTB1,SPTLC2,STK17A,SCARB2,ETS2,NAT1,ITPR1,CCDC69,NR4A2,MDH1,LTBP2,PLOD3,IFI6 |
| 1.783e-11 | -24.75 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | 195 | 52 | 17758 | 1761 |
ARHGAP11A,CASP3,TXN,SPC25,DEPDC1,CKAP2,CENPI,NDC80,CDCA8,KIF23,NUF2,STIL,CENPN,TOP2A,CD109,E2F7,PSMD1,IMPAD1,PASK,NEK2,BUB1,ALDH7A1,HYLS1,IQGAP3,MYBL1,C12orf75,CKS2,HMMR,PLK1,CENPA,KIF20A,FIGNL1,ASPM,PBK,CDC20,MYBL2,NUSAP1,NEURL1B,KIF11,CDK1,FAS,PRDX4,FAM64A,NGFRAP1,FAM83D,AURKA,CENPE,UBE2C,CCNB2,ESPL1,CPPED1,MELK |
| 1.818e-11 | -24.73 | GNF2_CCNB2 | MSigDB lists | GNF2_CCNB2 | 56 | 25 | 17758 | 1761 |
HMMR,ZWINT,KIF20A,DLGAP5,FOXM1,CKAP2,ASPM,PBK,CDC20,PTTG1,NDC80,CDCA8,NUSAP1,KIF11,CDK1,TOP2A,PLK4,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,MELK,CKS2 |
| 1.840e-11 | -24.72 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 738 | 131 | 17758 | 1761 |
ACACB,SLC25A13,ARFGEF1,NENF,NANS,ITPR2,LACTB2,SLC20A1,TYMP,RPS6KA2,SNX16,CTTN,TRAM1,S100A13,APOBEC3G,CD55,GALNT7,LHFPL2,CDK1,ABR,MAN2A2,ANKRD10,TMEM164,MSL1,WIPI1,GNPTAB,P4HA2,PRKCDBP,HDAC1,MRPS28,GLA,RAP1GAP,TRAF5,LZTS1,CDK17,PARP12,LGALS3,CHCHD7,TBC1D1,HLA-E,HLA-F,ITGA6,ASB9,COX6C,GNS,FRY,COL6A1,OPN3,DAPK1,FXYD5,SORL1,HLA-C,FAR2,MPHOSPH9,ABCC1,ZNF84,OXR1,CDK5R1,FRMD4B,SOX13,GNAS,ETS2,NR4A2,ARPC2,DOCK9,NQO1,DLGAP5,S100A11,IQGAP1,PSME2,RGS20,COL18A1,KCTD12,MGST2,APPBP2,IER3,NOV,CDH1,EFR3A,KIF14,REEP1,NOTCH3,CKS2,DOCK4,TIMP2,SYNE2,PTGER4,HTATIP2,NUSAP1,SLC11A2,FZD7,AMZ2,TAPBP,DNAJC10,IDE,CDK19,C19orf66,PEX2,INPP4B,VSIG10,BIN1,DAP,ATP9A,GTF3A,GDF15,INTS8,NTAN1,NUCB2,CTSC,ALG13,SGK1,WWP1,TAGLN2,SGCB,ATP2B1,S100A6,NCOA2,PHF20L1,ZC3H11A,GUSB,IFITM3,DIAPH2,AK4,PRDX4,HLA-B,NETO2,ARRB1,FHL1,GEM,FZD5,PLOD3 |
| 1.893e-11 | -24.69 | organelle | cellular component | GO:0043226 | 12606 | 1376 | 17570 | 1756 |
HECA,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CMTM6,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIPARP,MGAT5,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,COX6C,FAM21C,TTYH3,MARCH8,TFAP4,FRY,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,ZMYM1,MYLIP,NUP85,PPP6R1,MCCC2,REC8,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,S100A5,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,TPRN,NQO1,CD82,PTTG1,C5orf30,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CKAP2,DCAF7,ESRP1,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,ITGB8,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,PVRL4,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,RINL,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,BCL6,PLK4,ZDHHC23,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,SERINC2,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,ZNRF2,BHLHE41,RPL39,VASN,DAPK1,TPST1,PRKG1,OSTF1,CYSRT1,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,ST14,THRA,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ITPR3,ALCAM,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,EPCAM,RAB15,HSF2,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,SNX7,TPGS2,ELK3,VWA1,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,ECE1,EPB41L4B,SEPHS1,CHP1,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,ENO2,TSPAN15,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,ENDOD1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,RAP2C,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,LYNX1,IL18,MORF4L2,SYTL4,BARD1,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,ALDH1A3,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,EGLN1,XDH,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,SLC9A6,SIPA1L1,TRABD2A,RGS14,TTC8,NKX3-1,RASSF7,PDIA3,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,ADD3,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,UNKL,MYL9,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,ELF5,DUSP10,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,ALDH3A2,C9orf9,ABCC1,CYP26B1,CHSY3,MRPS33,PCBP3,CORO2A,SPATA13,TCF7,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,TIMP2,EVA1A,MBP,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,SIRPA,CCDC92,BUB1,ABCD1,KLF9,TLE6,FAH,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,FUCA1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,TMC5,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,FAM101B,CENPN,NCS1,SESN3,CTGF,IQCE,ZFP36,RGS3,STEAP2,AOX1,MTMR11,PACSIN1,LAMP2,LOC81691,KIFC2,SNTB2,PBK,HSPA12A,CASP9,TNS1,AGO4,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,TP53I3,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,FAM110C,SARAF,DHTKD1,TRAF5,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,BDH1,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,MMD,ZNF84,MFI2,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,FRMD4B,FAS,DGKH,PRKAG2,DCK,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,BROX,KCTD12,CD274,SNN,AIFM2,MNS1,APLP2,ZNF75D,CDKN1B,DAB2IP,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,HS3ST3B1,NR3C2,WASF3,NUDT6,PCOLCE,ATP9A,ARL4C,CCNJL,APOBEC3H,SEPP1,SPR,LGALS3BP,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,NCOA2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,NUCB1,CSTF2,GPER1,ARSB,NCAPG2,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,HEBP1,CAMKK1,DNER,TMC1,SH3KBP1,TSEN34,ABCD4,CHPF,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,MRPS36,PTGFRN,STK17B,CXXC4,NEIL1,ZNF114,UEVLD,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,RFX5,NCEH1,LRIF1,KDELR1,OXR1,GYLTL1B,HMG20B,MUM1L1,GLCE,GNAS,FECH,ONECUT1,NUDT16,PLPP3,UTP14C,CDCA5,NFKBIA,ALPK3,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,ANXA3,SORT1,FRMD6,POC1B,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,MDM1,MLPH,ADORA1,GALNS,KIAA0319,SYPL1,SUN2,RAB3B,NR4A1,ASPM,MBNL3,OGDHL,KLHL2,HLA-B,GAREM2,C2orf70,HNRNPH2,PRCP,DHRS2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 1.920e-11 | -24.68 | regulation of Ras protein signal transduction | biological process | GO:0046578 | 185 | 51 | 16441 | 1675 |
ARHGEF3,ARAP3,ADGRG1,FOXM1,ARHGEF11,RASA2,ARFGEF1,ERBB2,ARHGEF40,ARHGEF16,EPS8L2,ARHGEF10L,ITGA3,RALGPS2,ARHGEF37,KIF14,BCL6,DAB2IP,RASGEF1A,TIAM1,F2R,ALS2CL,SPRY2,RASGRP1,FARP2,RASGRF1,TIMP2,ARHGEF28,SPATA13,STMN3,ICMT,ARHGEF26,ABR,RASA1,ARHGAP35,ARHGAP24,PLEKHG6,ARHGEF19,CSF1,MADD,PLEKHG1,FGD6,ARRB1,NRG1,ARF6,F2RL1,ARHGEF9,ABCA1,ARHGEF4,FGD1,ARFGEF3 |
| 2.063e-11 | -24.60 | ERB2_UP.V1_UP | MSigDB lists | ERB2_UP.V1_UP | 184 | 50 | 17758 | 1761 |
BCAM,PAPSS2,ENO2,HOXB7,EPAS1,GALNT12,CAST,CNOT8,SOX9,ETV5,GDF15,CA8,FAM46C,PARM1,APOBEC3B,CYP1A1,KCNN4,MGAT4A,DRAM1,OPN3,BCL6,CADPS2,LIMCH1,NOTCH3,PDE4D,TSPAN1,EGLN3,SLC12A2,ULBP2,PTPRE,ZNF365,S100A6,CYP1B1,FADS2,PCDH1,PTPRU,SAT1,PTGER4,VWA1,NPC2,DUSP4,SLC6A6,SERPINA1,WIPI1,SLC9A6,P4HA2,CLMN,EPB41L4A,ABCG1,RRAGD |
| 2.268e-11 | -24.51 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 778 | 136 | 17758 | 1761 |
HECA,GNPDA1,IL18,F11R,PJA2,HSF2,ZFP36,KLF3,PIK3CA,ANKRD12,DUSP10,SNX16,RP2,ARMCX6,RCAN3,TIPARP,ING1,CD55,ITCH,RNF19B,LHFPL2,STK17B,POR,OPTN,PGF,ANKRD10,GPRC5B,KLF12,WIPI1,KCNK1,P4HA2,RAB11FIP1,ZNF165,KLF11,TANC2,F2RL1,MAFF,NR2C2,RRAGD,RMND5A,CDK17,LGALS3,CDKN1C,ZNF395,FAM169A,DNAJB2,C6orf106,RAB6A,DHRS3,PRRG4,IGF1R,LYPD3,MAP3K9,PIM1,LRIF1,GPR161,GFPT1,ZNF84,SPTLC2,STX3,AP1AR,SLCO4A1,NCOA3,SLC6A6,ETS2,CSNK1G1,NFKBIA,FGD6,TMEM159,PER3,TOB1,PLA2G4A,SORBS1,UPF3B,ARMCX3,IL15,CCDC68,FTH1,SNN,PHLDA1,TNFSF9,APPBP2,IER3,NOV,DOK4,VAT1,CNNM4,CTH,PPIF,SIRT1,MBP,RIPK2,COQ10B,SAT1,C3orf52,DNAJB14,FZD7,GABARAPL1,IRS2,CDK19,TLE1,IRF7,NRG1,KLF5,ABCA1,GCLM,ARHGEF3,FAM134A,BTN3A1,GDF15,DSE,DNAJB9,SLC25A36,SGPL1,PLEKHF1,FAM102A,KLF9,CITED2,CLIP2,SPRY2,ATP2B1,OSGIN1,WBP5,GCLC,EIF5A2,FOS,BSDC1,SWAP70,NR1D2,RND3,GEM,ZMIZ1,SLC25A38,HIPK3,AHR,GOLGB1 |
| 2.277e-11 | -24.51 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 308 | 70 | 17758 | 1761 |
SLC25A24,PKP2,PDGFB,SDC1,PHLDA1,NCS1,IER3,NPNT,DPYSL2,STEAP2,VAT1,ACSL4,SP5,CYP1B1,TIMP2,AKT1,SH3BGRL,SERTAD4,LOXL2,DUSP4,CMTM7,IRS2,PDLIM3,PLK2,CORO1C,AXL,BMP1,EFNA5,ANXA3,ARAP3,SCOC,NUAK1,ARL4C,HMGN3,COL4A5,TNFRSF19,ETS1,TTYH3,TMCC3,ITGA3,CYR61,FLRT3,CALD1,UBE2J1,TNFRSF12A,TAGLN2,CITED2,S100A6,AMOTL2,PRSS23,LPGAT1,AMFR,PRICKLE1,EPHA1,AIF1L,TCEAL8,STEAP1,MUM1L1,FRMD4B,GNAS,PITX2,PLOD2,RND3,TMEM30A,CSF1,CSNK1G1,RYK,ITGAV,PKIA,KLF7 |
| 2.571e-11 | -24.38 | organ development | biological process | GO:0048513 | 2766 | 381 | 16441 | 1675 |
GAA,HECA,ADD1,LGR4,HSPG2,AK7,RET,NRG2,PLXNA1,CCNB1,FAM101B,CALM2,CYP1A1,CTGF,STIM1,ALDH1A3,IL31RA,PIK3CA,CLDN4,TACSTD2,PIK3CD,SEMA3G,ZBTB18,TIPARP,SPEF2,SGCE,CASP9,TFAP2C,LOXL2,SAV1,ICMT,LDB2,CCNF,ZFAND5,ARF4,ABR,ENPP1,HLF,ATP7B,TRAF3IP1,NKD1,LRIG1,BMP1,HDAC1,DHTKD1,ARF6,F2RL1,GAB1,E2F8,HOXC13,FGD1,SEMA6B,SCN5A,CDKN1C,ITGA6,SOX9,SLC25A27,RAB23,GPSM2,HERC6,MERTK,TNFRSF19,KIAA1161,LMNA,ELF3,MECOM,ITGA3,CYR61,FLRT3,MEGF8,BHLHE41,PRKG1,IGSF3,EPB41L5,REC8,SALL4,ANO6,CALM1,AMER1,NPHP3,NFIB,GNA11,FAS,NCOA3,SEMA4D,FAM83D,PCDH19,NR4A2,GDF11,NDE1,XDH,ADAMTS16,EGLN1,PAPSS2,GRHL2,ST14,THRA,IQGAP1,CAST,RPS6KA1,PKP2,BCL2L1,DDR1,TNFSF9,RCN1,CCND1,APLP2,NOV,CDH1,CNNM4,CDKN1B,DAB2IP,RTKN2,EPHB4,PDE4D,SNX10,ETV4,MYT1,SEMA3B,FZD4,UTRN,SLC11A2,PYGO1,FZD7,CMTM7,NFIX,IRS2,PDLIM3,WFS1,CORO1C,AXL,PNPLA6,KLF5,NRG1,COBL,CBX7,MAPK12,CTHRC1,NKX3-1,TNRC6C,CENPI,SDC4,PBX3,CTSZ,PKN1,PLPPR4,SEPP1,ETS1,HOXB2,FGF19,EFNB1,SIX4,SGPL1,CTNNBIP1,E2F7,ITGB8,PTEN,FJX1,CST3,BAX,CD9,ADAM15,ATP8B1,TMBIM6,ERBB3,CITED2,SGCB,SPRY2,FARP2,TGIF1,ADAMTS2,PDGFC,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,AK4,FOS,CRISPLD2,GPLD1,CDK5RAP1,PITX2,ACVRL1,FGFR2,DBI,TBX18,NR4A3,RYK,FHL1,LRRK1,FZD5,OSR1,WDR62,USF2,SLC25A38,MELK,JARID2,EXPH5,CASP3,EMX1,EPAS1,EPHA4,NDRG2,DNER,SDC1,PDGFB,CACNB4,TMC1,SPTB,PLS3,EPCAM,RPS6KA2,LRRC6,NPNT,DPYSL2,IMPAD1,ELF5,MITF,DLG1,TMEM143,AKR1B1,MYH14,BTBD3,NEB,SP5,CYP1B1,THRB,CELSR2,NFE2L1,EZR,CR2,PRKRA,ANLN,IDH1,EDNRA,MDK,HS6ST1,HOXA9,NRGN,MAFF,CAPN1,PCSK5,RUNX2,SERPINE2,BVES,CALM3,CNTNAP2,NCKAP1,DHRS3,IL18R1,TNS3,DAZAP1,CA2,IGF1R,GATA2,FRAS1,WNT3A,SLC12A2,ETV7,MDFI,CYP26B1,HMG20B,TCF7,EIF2AK1,SCRIB,C3orf58,CDK5R1,BCAR3,MAPKAPK2,GNAS,FECH,ONECUT1,COL13A1,ITGA7,PHLPP2,CSF1,PRPS2,ALPK3,JAK3,SHROOM2,CCNB2,SEMA3A,RARG,HOXB7,NF2,IL15,FOXM1,TP53,COL18A1,ERBB2,MRAS,OSR2,PHLDA1,STIL,TTC21B,PDGFA,SETDB2,ARTN,KIF14,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,TWIST1,DIXDC1,ECE1,NOTCH3,MINPP1,DVL2,SULF2,SIRT1,MBP,AKT1,PTPRU,OSTM1,S100A4,PTGER4,GLO1,IGSF8,DAG1,SOCS3,ARHGAP35,PTPRJ,BFSP1,PTK7,OVOL1,PTBP3,TLE1,LTA4H,LIFR,ANXA3,COL9A3,CDH22,ADGRG1,LRP4,AES,TGFBR1,PPP2R3A,FZD6,NRP2,HDAC9,ZDHHC21,TOP2A,FOXP2,CD109,MDM1,ADRBK1,BMP7,TOX2,TFAP2A,SYK,MYO5A,GCNT1,HES1,RHOA,ASPM,RC3H2,PPARA,TTC7A,RUNX3,FNDC3A,BBS2,FOXL1,PRDX4,FAT4,TWSG1,DHRS2,CTSV,SPINT2,ARRB1,PPP2R3C,HOXB13,PLOD3,ZMIZ1,SOX8,AHR |
| 2.612e-11 | -24.37 | GNF2_CENPF | MSigDB lists | GNF2_CENPF | 61 | 26 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,HJURP,FOXM1,CKAP2,ASPM,CDC20,PTTG1,NDC80,MYBL2,CDCA8,NUSAP1,CCNF,KIF11,CDK1,FANCI,PRIM1,TOP2A,PLK4,AURKA,CENPE,UBE2C,CCNB2,E2F8,CKS2 |
| 2.733e-11 | -24.32 | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | 168 | 47 | 17758 | 1761 |
CCDC109B,DEPDC1,DLGAP5,HJURP,FOXM1,SOX9,PTTG1,NDC80,KIF23,NUF2,PM20D2,CCNB1,BARD1,DDR1,FANCI,MECOM,TOP2A,KIF14,NEK2,TMEM51,NCEH1,SLC39A10,ETV4,CKAP4,ABCC1,ZWINT,MMD,KIF20A,SALL4,ASPM,PBK,CDC20,NUSAP1,LRRC1,GALNT7,ANLN,KIF11,LHFPL2,CDK1,ATP1A1,CDCA5,CDCA7L,AURKA,CENPE,UBE2C,CCNB2,E2F8 |
| 2.759e-11 | -24.31 | phosphorylation | biological process | GO:0016310 | 1198 | 193 | 16441 | 1675 |
NMRK1,AK7,CAMKK1,EPHA4,RET,NRG2,PSME1,IL18,CAMK1D,CCNB1,PDGFB,SPTB,GRM5,CALM2,DAPK2,WEE1,PSMD1,RPS6KA2,SHC3,IMPAD1,PAPSS1,IL31RA,PASK,PIK3CA,DUSP10,PIK3CD,RASGRP1,PLK1,ACVR1C,PBK,ROR1,PRKRA,CDK1,STK17B,ADRBK2,PLK2,LIMK1,GNPTAB,NOD2,CAB39,DHTKD1,PIK3C2B,ITPKA,GAB1,PRKAA2,CDK17,LMTK3,NUAK1,RASA2,DGKQ,SOX9,CALM3,NDUFA4,ADCK5,TEC,TNFRSF19,MERTK,BMP2K,IGF1R,PPP4R1,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,MDFIC,ALPK1,PIM1,PIKFYVE,NCAM1,MAST4,DGKG,MDFI,PMPCB,MMD,TESK1,ADCK3,STAT4,CALM1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ELK1,PDIK1L,PSMA4,CDK5R1,RASA1,STK17A,DGKH,MAPKAPK2,PRKAG2,CSNK1G1,DCK,PRPS2,AURKA,ALPK3,STK39,CDK18,MAP3K5,JAK3,NRBP1,SPRED1,PAPSS2,IL15,RPS6KA1,PSME2,ERBB2,TESK2,GRK6,PRKACA,DDR1,PDGFA,CCND1,DOK4,PLK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,F2R,SCYL3,FRS3,SEPHS1,MAP3K3,RIPK2,AKT1,PANK1,PTGER4,PRKCQ,PKMYT1,XRCC6BP1,DUSP4,MAP3K6,EPHA10,IRS2,JAK1,CDK19,STK26,AXL,STK38,PTK7,NRG1,SPTBN5,MLKL,ST3GAL1,MAPK12,PINK1,ENO2,CIT,GNE,PSMD10,TGFBR1,PKN1,TRIB2,FGF19,ADRBK1,CDK16,FAM20B,SGK3,SGK1,BUB1,MAPK11,ERBB3,IQGAP3,SYK,RASGRF1,PGM1,PSMB4,RAPGEF2,PIK3R1,GRIN1,OGDHL,NADK2,AK4,RUNX3,YES1,FOS,MAPK8IP1,DGKE,PRDX4,FGFR2,ACVRL1,SCG2,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,HIPK3,MELK |
| 3.052e-11 | -24.21 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | 180 | 49 | 17758 | 1761 |
ANXA3,TRIM2,ALDH6A1,CDKN1C,CAST,IQGAP1,BLVRB,CTDSPL,ASAH1,KCTD12,COL4A5,IL27RA,TGOLN2,SEPP1,MERTK,CARD10,MECOM,CDS1,PLS3,SP100,CDH1,FRY,EFR3A,LLGL2,KIF13B,PLCG2,MITF,TPST1,TACSTD2,IFIT1,AMOTL2,LAMP2,NR3C1,ATP1B1,LDB2,ALCAM,ATP10D,CYB5A,FUCA1,NCOA3,ATP1A1,PPP2R5A,GPRC5B,ETS2,PRCP,AXL,PRPS2,MATN2,TOB1 |
| 3.150e-11 | -24.18 | PLASARI_TGFB1_TARGETS_10HR_DN | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_DN | 234 | 58 | 17758 | 1761 |
LMO7,TRIM2,REPS2,NQO1,LGR4,DDIT4L,IL18,NUF2,HERC6,CCNB1,DHRS3,FOXP2,SESN3,PTEN,METTL7A,IL6ST,TRIM21,BUB1,DIXDC1,IFIT1,SCARA3,SLC12A2,TLE6,PARP9,CYP1B1,HMMR,SMARCA2,FIGNL1,SH3BGRL,USP18,PIK3R1,CBX6,MBNL3,PDE5A,NUSAP1,PRKAR2B,IFIT3,LDB2,IDH1,SESN1,NFIB,MUM1L1,NFIX,PRIM1,PLEKHH2,FAT4,RND3,NR1D2,FGFR2,MAP2,NMI,PLEKHG1,CLIP4,PER3,OSR1,SERPINB1,SEMA3A,LIFR |
| 3.168e-11 | -24.18 | bounding membrane of organelle | cellular component | GO:0098588 | 2293 | 321 | 17570 | 1756 |
SUN1,LAMP1,GAA,ACACB,SLC35D2,IL15RA,ATP8A1,DNAJC3,RET,TAP1,SYTL4,PJA2,NCS1,SLC9A7,PQLC2,CYP1A1,AP1M2,STIM1,CABP1,CYP2S1,STEAP2,FUT1,SNX16,MARCH2,MGAT5,ERAP2,LAMP2,SPATA18,SNTB2,SLC35C1,KIF13A,GALNT7,MCFD2,ICMT,POR,CYP4F3,ENPP1,DNM1L,GNPTAB,ATP7B,SARAF,ARF6,SCOC,GGA1,HLA-E,TMEM55B,RAB23,SLC36A4,FAM21C,MARCH8,DOPEY2,ZNRF2,SNX18,VASN,FLRT3,TPST1,PCYOX1,NCAM1,PIKFYVE,PPP6R1,GPR161,FAM69A,FADS2,B3GNT7,MMD,LPGAT1,ERO1A,ATP8B3,SPTLC2,ANTXR1,GNA11,CYB5A,SCARB2,FAAH,ITPR1,MAP3K5,PLIN3,TMEM173,EHD1,PLA2G4A,ARMCX3,TCTN2,NLRX1,GALNT12,ATP2C2,BCL2L1,MGST2,MVB12B,SNN,AIFM2,APC2,CYP39A1,ZFYVE9,CDS1,ACAP2,SCNN1A,XYLT2,ACSL4,TSPAN1,RAB27B,SNX10,TMEM9,MX1,SEC23A,SEC61B,COG2,FZD4,SYNE2,CYS1,SLC11A2,DNAJB14,PKMYT1,RAB38,ITPR3,TRIQK,ATP10D,GABARAPL1,DDOST,STK26,WFS1,SLC9A6,PNPLA6,HS3ST3B1,NR3C2,TTC8,ATP9A,CTSZ,HLA-A,SGPL1,FUT2,CTSC,MGAT4A,ALG13,FUT8,FAM20B,DRAM1,CD9,BAX,SLC44A2,PLEKHF1,TMBIM6,TPCN1,ACBD5,PDGFC,B3GNT2,EIF5A2,ELOVL3,FURIN,C1GALT1C1,CPTP,GPLD1,GALNT3,NUCB1,PLOD2,SYT7,RAB11FIP2,ERAP1,GPER1,FZD5,WDR45B,ESYT2,EPHA4,ARFGEF1,MGAT5B,ITPR2,PDGFB,CHPF,ABCD4,ZFYVE16,RAB15,SLC44A1,DLG1,ABCA2,RAB20,TECR,SCARA3,MYRIP,TRAM1,RASGRP1,CYP1B1,LAMP3,ATL1,NFE2L1,PTGFRN,RHEB,OPTN,MAN2A2,HS6ST1,HPSE,AGPAT2,WIPI1,DOLPP1,RAB11FIP1,PIEZO1,NRGN,RAP1GAP,STARD3NL,RRAGD,BMF,LMTK3,PEX6,FXYD3,HLA-F,RAB6A,B4GALT4,DHRS3,B4GALNT1,B3GALNT1,COL6A1,SUCO,SELK,HLA-C,FAR2,WNT3A,GAD1,ALDH3A2,MPHOSPH9,CKAP4,KDELR1,CHSY3,CYP26B1,MGAT4B,GYLTL1B,EMC2,C3orf58,STEAP1,GLCE,GNAS,MFSD2A,PHLPP2,PLPP3,TMEM30A,ZDHHC7,CTSA,PLD1,APOL2,PROM2,XYLT1,PDIA5,ERBB2,FAM198B,LPIN3,EMP2,BCAP31,CYP26A1,PDGFA,ATP6V0B,WDR44,CYP4F11,REEP1,VAT1,RPN2,NOTCH3,ECE1,LMAN1,PDIA6,CHP1,CLCN3,EVA1A,OSTM1,C3orf52,CASP4,ATP13A2,TAPBP,PEX2,SPTBN5,IRF7,CYP2U1,REEP4,ST3GAL1,NDST3,ARFGEF3,MAN2B2,ANXA3,GOLIM4,PACSIN2,PINK1,SORT1,CD63,POMGNT1,DSE,LBR,DNAJB9,VPS26A,PARM1,TMEM63A,ZDHHC21,M6PR,A4GALT,RRBP1,KIAA0319,UBE2J1,SGK1,ABCD1,GCNT1,B3GALT6,SUN2,RHOA,RAB3B,IFITM3,AMFR,PLAUR,SYBU,LITAF,COL7A1,FNDC3A,TXNDC11,BBS2,MAPK8IP1,HLA-B,SERPINA1,RND3,RAP2C,PGRMC1,ARRB1,SPCS3,PLOD3,NDFIP1,PTGES,GOLGB1,ABCG1 |
| 3.284e-11 | -24.14 | MODULE_180 | MSigDB lists | MODULE_180 | 109 | 36 | 17758 | 1761 |
BCAM,BLVRB,CRABP2,PDGFB,ARHGEF16,SYTL2,CDS1,ELF3,IL17RB,EPCAM,SCNN1A,MLPH,KIAA1107,CDH1,METTL7A,LLGL2,BMP7,BDH1,CD9,CLDN4,ERBB3,SULT2B1,DPYSL5,SSH3,TFAP2C,AIF1L,CYB5A,MDK,TJP3,NAT1,SPINT2,MAL2,ANXA9,HOOK1,ISOC1,OCLN |
| 3.431e-11 | -24.10 | BASAKI_YBX1_TARGETS_UP | MSigDB lists | BASAKI_YBX1_TARGETS_UP | 272 | 64 | 17758 | 1761 |
S100A11,PTTG1,NDC80,NUF2,CCNB1,FAM101B,EMP2,CENPN,FANCI,CTGF,SIVA1,NTN4,RNF26,MYBL1,CTH,PLK1,TIMP2,CENPA,PBK,CDC20,CDA,HTATIP2,ANLN,H2AFV,CDK1,RHEB,DPYSL3,PLK2,ZNF367,AXL,ANXA3,PINK1,HJURP,DEPDC1,CENPI,FRMD6,CDCA8,KIF23,S100A2,GSTP1,SAC3D1,E2F7,DAZAP1,CYR61,NEK2,BUB1,TNFRSF12A,DDB2,ZWINT,KIF20A,PRSS23,ASPM,BORA,RND3,NFKBIA,SH3BP4,FAM83D,AURKA,CCNB2,UBE2C,ESPL1,L1CAM,MELK,RUSC1 |
| 3.438e-11 | -24.09 | positive regulation of metabolic process | biological process | GO:0009893 | 3495 | 463 | 16441 | 1675 |
ACACB,TXN,LGR4,DNAJC3,HEXB,RET,NRG2,PSME1,IL18,MORF4L2,CAMK1D,CCNB1,BARD1,CARD10,GRM5,CALM2,PSMD1,CTGF,ZFP36,RGS3,IL31RA,FOSB,SERINC2,PIK3CA,IRF2,PIK3CD,TIAM1,TIPARP,SMARCA2,TNIP1,ACVR1C,CASP9,TFAP2C,PRKAR2B,F12,LDB2,SAV1,RNF19B,POR,ARF4,ARHGEF26,ABR,AHRR,PIAS3,PLCG1,MID1IP1,ANKRD6,PLK2,NKD1,NOD2,AGFG2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,GAB1,HOXC13,FGD1,DDX58,CDKN1C,SCOC,GGA1,TBC1D1,ITGA6,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,ITGA3,RALGPS2,CYR61,SNX18,FAM13B,RANBP1,NEK2,DAPK1,MAP3K9,SORL1,MYDGF,NCAM1,MYLIP,NUP85,RIMS2,GPR161,SOCS5,MMD,MFI2,TBC1D8B,SALL4,STAT4,CALM1,PYM1,MYBL2,PIP4K2C,EPHA1,ELK1,TP53INP2,PSMA4,NFIB,PLIN5,RASA1,FAS,MMP15,NCOA3,PRKAG2,ETS2,SEMA4D,PELI2,SETD3,ITPR1,FGD6,AURKA,NR4A2,STK39,GDF11,MAP3K5,TMEM173,XDH,DOCK9,ARHGAP11A,SPRED1,ARMCX3,GRHL2,DLGAP5,THRA,RPS6KA1,RALBP1,IQGAP1,RGS20,MGST2,PRKACA,APC2,EPS8L2,CCND1,ST5,ACAP2,CDH1,SP100,SH3BP1,DACT1,CDKN1B,DAB2IP,RASGEF1A,ETV4,MYT1,MED30,DOCK4,RIPK2,FZD4,FOXJ2,CDCA2,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,GTF2A2,FZD7,NFIX,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,CORO1C,WFS1,SIPA1L1,PLEKHG1,SLC27A1,KLF5,NRG1,RGS14,DENND5B,MAPK12,ARHGEF3,PCOLCE,NKX3-1,TNRC6C,DEPDC1,CKAP2,SDC4,PBX3,PKN1,ETS1,GSTP1,ARHGEF40,FGF19,TEAD3,SIX4,WWP2,E2F7,ITGB8,RNF128,CTSC,PTEN,CST3,BAX,PLEKHF1,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,FURIN,YES1,GRTP1,FOS,GPLD1,PITX2,FGFR2,NR1D2,ACVRL1,RYK,NR4A3,GRIN2D,GPER1,CENPE,HMGA1,LRRK1,FZD5,OSR1,USF2,ESPL1,RGMA,JARID2,CASP3,EPAS1,CNOT8,CAMKK1,CUL4B,EPHA4,ARFGEF1,DNAJB11,F11R,NENF,ITPR2,HDAC6,PDGFB,ERP29,DENND2D,SPTB,FANCI,ARHGEF10L,EPCAM,SIPA1L2,RPS6KA2,HSF2,GRHL1,NPNT,SHC3,ARHGEF37,IL6ST,ELF5,PASK,MITF,DLG1,RP2,SLC39A10,MYBL1,RASGRP1,ZNF462,PLK1,THRB,PCGF5,TRIM8,CITED4,ITCH,NFE2L1,EZR,ARHGDIB,PRKRA,CDK1,EDNRA,KDM4D,MDK,PLEKHG6,ARHGEF19,GPRC5B,KLF12,MADD,PRKCDBP,CAB39,RAP1GAP,MAFF,NR2C2,PRKAA2,PIFO,RUNX2,ARAP3,BVES,DNAJB2,RASA2,ETV5,ASB9,CALM3,TEC,FBLN1,DAZAP1,IGF1R,RINL,GATA2,TBCD,SUCO,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,CCDC88A,MDFI,ELK3,RGMB,SPATA13,STRADB,PDE5A,SCRIB,CDK5R1,RASGRP2,GNAS,MAPKAPK2,BCAR3,NUDT16,ONECUT1,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,CTSA,ATP1B3,JAK3,TOB1,RARG,KLF7,PROM2,SORBS1,AVPI1,UPF3B,FOXM1,IL15,PSME2,TP53,ERBB2,OSR2,LPIN3,EMP2,STIL,BCAP31,ARHGEF16,IER3,PDGFA,SS18,LMO4,KIF14,PLCG2,BCL6,CDH3,TWIST1,ECE1,EPB41L4B,NOTCH3,EGLN3,F2R,GM2A,DVL2,FRS3,CTH,CHP1,MAP3K3,SIRT1,CLCN3,TIMP2,AKT1,CDC20,SERTAD3,ERBB2IP,CD40,DOCK5,MAP3K6,ARHGAP35,JADE1,DNAJC10,RBL1,MMP17,TLE1,EFNA5,IRF7,SPTBN5,ABCA1,ARFGEF3,GLIS3,ANXA3,GCLM,PINK1,CD63,ARHGEF11,DAP,PSMD10,TGFBR1,GDF15,HMGN3,TRIB2,SBF1,PARM1,PPP2R3A,IRF2BPL,TOP2A,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,IQGAP3,SYK,NFE2L3,HES1,RHOA,PSMB4,NR3C1,PLAUR,NR4A1,GCLC,PPARA,RGCC,PRICKLE1,MAML2,RUNX3,ARHGAP24,BANK1,RAP2C,NMI,ARRB1,PPP2R3C,SOX8,ZMIZ1,NDFIP1,TBC1D4,UBE2C,AHR,ARHGEF9,RAB3IL1,ABCG1,ARHGEF4 |
| 3.607e-11 | -24.05 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 511 | 101 | 16441 | 1675 |
CASP3,SPRED1,PPP4R4,NF2,FOXM1,DNAJC3,IQGAP1,CTDSPL,TP53,NDRG2,CCNB1,PDGFB,SYTL2,IER3,CALM2,PDGFA,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,CRY2,TWIST1,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,PLK1,PPIF,SIRT1,CAMSAP3,TNIP1,AKT1,ITCH,PBK,CDA,EZR,PRKAR2B,PKMYT1,DUSP4,DAG1,SOCS3,EDNRA,IRS2,ENPP1,DNAJC10,PTPRJ,PPP2R5A,CORO1C,STK38,TRAF3IP1,SLC27A1,RGS14,HSPB1,F2RL1,ARFGEF3,PINK1,LMTK3,CDKN1C,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,GSTP1,FBLN1,TIPRL,SH2D4A,MECOM,CD109,TFAP4,IGF1R,PTEN,BMP7,BAX,SORL1,SPRY2,SOCS5,RHOA,CALM1,PPARA,EPHA1,RANBP9,MAPK8IP1,CDK5RAP1,SWAP70,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,GPER1,LRRK1,UBE2C,HIPK3,PKIA,XDH,EGLN1 |
| 3.607e-11 | -24.05 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 511 | 101 | 16441 | 1675 |
CASP3,SPRED1,PPP4R4,NF2,FOXM1,DNAJC3,IQGAP1,CTDSPL,TP53,NDRG2,CCNB1,PDGFB,SYTL2,IER3,CALM2,PDGFA,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,CRY2,TWIST1,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,PLK1,PPIF,SIRT1,CAMSAP3,TNIP1,AKT1,ITCH,PBK,CDA,EZR,PRKAR2B,PKMYT1,DUSP4,DAG1,SOCS3,EDNRA,IRS2,ENPP1,DNAJC10,PTPRJ,PPP2R5A,CORO1C,STK38,TRAF3IP1,SLC27A1,RGS14,HSPB1,F2RL1,ARFGEF3,PINK1,LMTK3,CDKN1C,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,GSTP1,FBLN1,TIPRL,SH2D4A,MECOM,CD109,TFAP4,IGF1R,PTEN,BMP7,BAX,SORL1,SPRY2,SOCS5,RHOA,CALM1,PPARA,EPHA1,RANBP9,MAPK8IP1,CDK5RAP1,SWAP70,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,GPER1,LRRK1,UBE2C,HIPK3,PKIA,XDH,EGLN1 |
| 3.625e-11 | -24.04 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 175 | 48 | 17758 | 1761 |
LMO7,NCKAP5,ARHGEF3,NUAK1,CAST,EPHA4,IL18,SLC1A3,SLC7A2,SEPP1,PDGFB,ADAMTSL4,FBLN1,CARD10,LGALS3BP,SNTA1,PLCG2,COL6A1,DRAM1,SCARA3,S100A13,GM2A,SCN3A,ADAMTS2,COL6A2,PLEKHA6,CDA,PRICKLE1,ZFAND5,PCTP,EPN3,TMEM30A,MATN2,NR4A3,CLIP4,CLMN,NFKBIZ,LTBP2,OSR1,ARSB,F2RL1,IFIH1,SERPINB1,LIFR,AHR,TMEM173,JARID2,MAPK12 |
| 3.976e-11 | -23.95 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 512 | 99 | 17775 | 1757 |
LGR4,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,SDC1,DDR1,DAPK2,WEE1,RPS6KA2,IL6ST,PIK3CA,FUT1,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,SMARCA2,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,TANC2,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,PSIP1,BMP2K,ADRBK1,IGF1R,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,ATP8B1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,ZRANB1,SYK,SYTL3,ADCK3,TESK1,ZNF320,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,GNA11,STK17A,DHX32,MAPKAPK2,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 4.058e-11 | -23.93 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10319 | 1147 | 17775 | 1757 |
AK7,SLC25A13,RET,ISOC2,LACTB2,DPP8,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,ITPKA,HSPB1,NXT2,SCN5A,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,ATG4A,TFAP4,FRY,RIMS3,MEGF8,RANBP1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,HPS3,ELK1,NPHP3,PCTP,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,CLMN,GDF11,ADAMTS16,DOCK9,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,MUC16,ST5,CDH1,XYLT2,RASGEF1A,DLG3,ZNF365,ETV4,SNX10,MYT1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,XRCC6BP1,SNX12,NFIX,PDLIM3,CDK19,CORO1C,AXL,PNPLA6,MAPK12,CTHRC1,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,CST3,BAX,FAM102A,IGFBP2,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,DBI,PPM1H,ITGAV,ACOT7,TLL2,TMEM131,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,HOXA9,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,ADCK5,RAB6A,HES2,NCKAP1,ANO1,TNS3,FRAS1,KIF13B,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,IDE,PTPRJ,RBL1,STK38,MMP17,IRF7,ZMAT1,BIN1,PINK1,CDH22,CPEB4,KLHL13,HAL,GDF15,HMGN3,LBR,H1FX,NRP2,DNAJB9,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,MAML2,GGH,COL7A1,TXNDC11,DGKE,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,SLC35D2,HSPG2,SSH1,VANGL1,TSC22D3,CAMK1D,PJA2,SLC9A7,ANKS6,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,ARMCX6,METAP2,ACVR1C,LDB2,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,ADCK2,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAM83D,CABIN1,CDK18,KLK7,HOOK1,IFIH1,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,RALBP1,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ACAP2,EPHB4,PDE4D,TSPAN1,MED30,DOCK4,COG2,FOXJ2,DRAP1,UTRN,PKMYT1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,NGFRAP1,CCDC149,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,CENPI,EPS8,HERC5,FBXO6,DNAH3,EFNB1,FGF19,SCML1,WWP2,RASSF8,E2F7,TMEM87B,GNB5,RNF128,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,CXorf56,MELK,DEF6,UGT8,VARS2,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,METTL7A,ANKFN1,TRPC1,CTTN,MYRIP,BTBD3,NLRP4,CENPA,USP18,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,CALM3,COL6A1,LIMCH1,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,ELK3,VWA1,HEATR5A,NUBP1,PDIK1L,STEAP1,RANBP9,UAP1,TMEM30A,SH3BP4,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,SORBS1,HDAC11,PDIA5,MRAS,CYP4F11,KIF14,FABP6,EPB41L4B,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,TLE1,ABCA1,ENO2,ARHGEF11,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,RRBP1,ARVCF,CLIP2,RBMS2,B3GALT6,PGM1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,NRG2,DHX8,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,WEE1,PQLC2,PSMD1,KLF3,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,ANKRD6,LIMK1,SERPINB6,ARF6,E2F8,GAB1,HOXC13,FAM169A,SOX9,MERTK,LMNA,ELF3,RAVER2,FAM189A1,NEK2,NCAM1,C9orf72,SALL4,STAT4,MYBL2,TP53INP2,DHX32,STK17A,PTPRF,NCOA3,TIMM8A,ITPR1,AURKA,MDH1,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,PAPSS2,TMSB15A,GALNT12,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,CAMSAP3,FZD4,PLEKHO1,SYNE2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,RGS14,NKX3-1,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,SLC27A6,ARSG,CTSC,ALG13,CALD1,PLEKHF1,ADAM15,NKAPP1,MAPK11,WWP1,NPTXR,TPCN1,LCA5,BCL9,RAPGEF2,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,FHL1,HMGA1,CENPE,DCBLD1,SIGIRR,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,NUP62CL,PDGFB,CNTRL,SHC3,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,MCTP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,CNTNAP2,DHRS3,IL18R1,IGF1R,GATA2,SPIN4,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,IFIT3,ANKRD29,G2E3,MAPKAPK2,PVRL2,ITGA7,PRPS2,LTBP2,NIPA1,RNF146,NF2,UPF3B,FOXM1,XYLT1,ERBB2,CCDC68,FAM198B,LPIN3,CYP26A1,RAD23A,PLCG2,SCN2A,EGLN3,MINPP1,DVL2,CTH,SIRT1,CPD,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,NDST3,CMTM4,MAN2B2,COL9A3,GOLIM4,TM2D2,MACC1,RUSC2,GNE,BLVRB,PSMD10,NKRF,DSE,SIRPA,PPP2R3A,ABCD1,BUB1,FAIM,IGDCC4,FAH,DLGAP1,HMMR,CRB3,NR3C1,AMFR,LITAF,PPARA,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,BANK1,FAT4,SERPINA1,ZNF214,NMI,NETO2,PGRMC1,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,GAA,TMEM41B,PPFIBP2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IQCE,PRICKLE3,RGS3,STEAP2,AOX1,ATRNL1,MTMR11,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,HSPA12A,CASP9,NBPF3,TNS1,PIF1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,NKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,DGKQ,SLC25A27,C6orf106,KIF23,KIAA1161,PRRG4,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,RUNDC3B,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,B3GNT7,DDB2,ZNF84,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,ARMCX3,TRIP10,RPS6KA1,IQGAP1,BROX,RNF182,CD274,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,NIN,CMTM7,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,MLKL,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,TMCC3,SNTA1,PTEN,SGK3,ATP8B1,CNOT6L,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,GPLD1,AMMECR1,CSTF2,PGM2L1,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,CASP3,LTBP1,CPT2,CAMKK1,FLYWCH2,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,TSEN34,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,ZCCHC12,TSPAN6,ANKRD12,POF1B,RAB20,RP2,SLC39A10,PTPRE,RASGRP1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,ARHGEF19,NEIL1,ZNF114,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,ZNF432,OTUD1,CA2,LRIF1,ALS2CL,OXR1,GYLTL1B,RNF113A,MUM1L1,GNAS,XKRX,BCAR3,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,PROM2,SPC25,MORC4,TDRKH,ARHGEF16,LRRC45,SS18,FRYL,TWIST1,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,IGSF8,ERBB2IP,DUSP4,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,LIFR,PPP2R2D,ANXA3,POC1B,FRMD6,LRP4,AES,NOTUM,TRMT2B,IL17RB,MLPH,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,NR4A1,LRRC66,MBNL3,OGDHL,KLHL2,C2orf70,HNRNPH2,OTUB2,HOXB13,GEM,L1CAM,SNPH |
| 4.138e-11 | -23.91 | upper_aerodigestive_tract | COSMIC cancer mutations | upper_aerodigestive_tract | 13823 | 1471 | 17775 | 1757 |
HECA,AK7,HEXB,RET,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,PAQR7,HPS3,PQLC3,ELK1,NPHP3,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM173,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,ISOC1,MAPK12,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,CST3,BAX,KLC3,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,GDF15,HMGN3,AIP,LBR,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,SNX16,HYLS1,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,ANKRD10,LRIG1,PRDM5,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,ADCK2,TPST1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,FZD7,AMZ2,DDOST,NGFRAP1,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,SP5,LAMP3,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,MADD,ZNF165,CAB39,SP6,GLA,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,PYROXD2,ETV5,ASB9,ABCG2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,APOL2,SNX30,LMO7,CCNE2,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,MORF4L2,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,FAM189A1,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,TPCN1,CRTAP,AMOTL2,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,GRIN1,MYEOV,SNTB1,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,DCBLD1,CYBRD1,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,HLA-F,ASAH1,CNTNAP2,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,PLCG2,LHX6,SRR,MINPP1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DUOX1,DNAJC10,PRRT4,ATP1A1,C19orf66,PTK7,ADAMTS14,C1orf43,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,MACC1,RUSC2,GNE,GABRG2,PSMD10,NKRF,DSE,CRABP2,SIRPA,PPP2R3A,SLC9A2,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,NR3C1,AMFR,LITAF,PPARA,CCDC34,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,FAM117A,PPP2R3C,UBE2C,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,TBC1D8B,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,NLRX1,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,ZCCHC12,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,MDK,CXXC4,LRRC42,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,LRIF1,ALS2CL,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,OVOL1,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,RAB3B,NR4A1,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 4.211e-11 | -23.89 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 248 | 60 | 17758 | 1761 |
CD99,IER5L,CASP3,KIAA1462,HLA-E,TSC22D3,DCAF7,CUL4B,EFHD2,KCTD12,BCL2L1,EMP2,EFNB1,SH3KBP1,SIRPA,ZDHHC21,RALGPS2,SNX18,GATA2,DPYSL2,PAQR5,BHLHE41,KLF3,TOX2,OPN3,STEAP2,DAPK1,IGFBP2,TSPAN13,NPTXR,TRIM62,SMAGP,MDFI,FBLN5,FZD4,SYNE2,PPARA,SPATA13,ARHGDIB,NEURL1B,RNF19B,SPTLC2,CDK1,STEAP1,FZD7,GLCE,FAS,FUCA1,GALNT3,PGF,TMEM164,ATP1A1,JAK1,TRIM69,NMI,RAB11FIP1,PGM2L1,HS3ST3B1,CMPK2,CPPED1 |
| 4.447e-11 | -23.84 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 352 | 76 | 17758 | 1761 |
CEP70,UGP2,HEBP1,CAST,DNAJC3,TSC22D3,HEXB,PKP2,PDGFA,TTC21B,FAM46A,CTGF,ARTN,UBE2T,KLF3,AOX1,STEAP2,TMEM37,EGLN3,PDIA6,CTDSP2,CCDC38,SULF2,PCGF5,C6orf1,SERTAD4,HTATIP2,LOXL2,DUSP4,PRKRA,IDH1,STK17B,ENPP1,TAPBP,WIPI1,RBL1,NFKBIZ,DENND5B,GRN,FBLIM1,HJURP,FBXO6,FGF19,TMCC3,PDIA4,FAM111A,E2F7,SPIN4,CYR61,COL6A1,SGK1,TRIM21,PLEKHF1,BUB1,PIM1,KLF9,CNOT6L,NCOA2,FAM69A,MOSPD2,PQLC3,TBC1D8B,UBE2A,PDE5A,GGH,BLVRA,FOS,PRKAG2,RND3,NR1D2,H1F0,PLD1,TMEM159,CEP41,DCBLD1,CYBRD1 |
| 4.664e-11 | -23.79 | LEE_EARLY_T_LYMPHOCYTE_UP | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_UP | 100 | 34 | 17758 | 1761 |
CD99,CEP70,DLGAP5,PTTG1,NDC80,NUF2,CCNB1,FANCI,TOP2A,E2F7,UBE2T,KIF14,NEK2,BUB1,FAIM,SYK,CKS2,HMMR,CENPA,KIF20A,ASPM,MPP1,PBK,GGH,CDCA2,NUSAP1,GALNT7,KIF11,CDK1,AURKA,CCNB2,UBE2C,E2F8,MELK |
| 4.786e-11 | -23.76 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10324 | 1147 | 17775 | 1757 |
AK7,SLC25A13,RET,ISOC2,LACTB2,DPP8,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,ITPKA,HSPB1,NXT2,SCN5A,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,ATG4A,TFAP4,FRY,RIMS3,MEGF8,RANBP1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,HPS3,ELK1,NPHP3,PCTP,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,CLMN,GDF11,ADAMTS16,DOCK9,CD82,PTTG1,C5orf30,GRK6,REPS1,APPBP2,MUC16,ST5,CDH1,XYLT2,RASGEF1A,DLG3,ZNF365,ETV4,SNX10,MYT1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,XRCC6BP1,SNX12,NFIX,PDLIM3,CDK19,CORO1C,AXL,PNPLA6,MAPK12,CTHRC1,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,CST3,BAX,FAM102A,IGFBP2,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,DBI,PPM1H,ITGAV,ACOT7,TLL2,TMEM131,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,HOXA9,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,ADCK5,RAB6A,HES2,NCKAP1,ANO1,TNS3,FRAS1,KIF13B,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,IDE,PTPRJ,RBL1,STK38,MMP17,IRF7,ZMAT1,BIN1,PINK1,CDH22,CPEB4,KLHL13,HAL,GDF15,HMGN3,LBR,H1FX,NRP2,DNAJB9,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,MAML2,GGH,COL7A1,TXNDC11,DGKE,SCG2,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,SLC35D2,HSPG2,SSH1,VANGL1,TSC22D3,CAMK1D,PJA2,SLC9A7,ANKS6,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,ARMCX6,METAP2,ACVR1C,LDB2,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,ADCK2,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAM83D,CABIN1,CDK18,KLK7,HOOK1,IFIH1,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,RALBP1,BCL2L1,DDR1,ZFYVE9,APOBEC3B,NOV,ACAP2,EPHB4,PDE4D,TSPAN1,MED30,DOCK4,COG2,FOXJ2,DRAP1,UTRN,PKMYT1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,NGFRAP1,CCDC149,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,CENPI,EPS8,HERC5,FBXO6,DNAH3,EFNB1,FGF19,SCML1,WWP2,RASSF8,E2F7,TMEM87B,GNB5,RNF128,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,CXorf56,MELK,DEF6,UGT8,VARS2,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,METTL7A,ANKFN1,TRPC1,CTTN,MYRIP,BTBD3,NLRP4,CENPA,USP18,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,GLA,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,CALM3,COL6A1,LIMCH1,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,ELK3,VWA1,HEATR5A,NUBP1,PDIK1L,STEAP1,RANBP9,UAP1,TMEM30A,SH3BP4,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,SORBS1,HDAC11,PDIA5,MRAS,CYP4F11,KIF14,FABP6,EPB41L4B,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,TLE1,ABCA1,ENO2,ARHGEF11,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,RRBP1,ARVCF,CLIP2,RBMS2,B3GALT6,PGM1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,NRG2,DHX8,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,WEE1,PQLC2,PSMD1,KLF3,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,ANKRD6,LIMK1,SERPINB6,ARF6,E2F8,GAB1,HOXC13,FAM169A,SOX9,MERTK,LMNA,ELF3,RAVER2,FAM189A1,NEK2,NCAM1,C9orf72,SALL4,STAT4,MYBL2,TP53INP2,DHX32,STK17A,PTPRF,NCOA3,TIMM8A,ITPR1,AURKA,MDH1,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,PAPSS2,TMSB15A,GALNT12,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,CAMSAP3,FZD4,PLEKHO1,SYNE2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,RGS14,NKX3-1,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,SLC27A6,ARSG,CTSC,ALG13,CALD1,PLEKHF1,ADAM15,NKAPP1,MAPK11,WWP1,NPTXR,TPCN1,LCA5,BCL9,RAPGEF2,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,FHL1,HMGA1,CENPE,DCBLD1,SIGIRR,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,NUP62CL,PDGFB,CNTRL,SHC3,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,MCTP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,CNTNAP2,DHRS3,IL18R1,IGF1R,GATA2,SPIN4,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,IFIT3,ANKRD29,G2E3,MAPKAPK2,PVRL2,ITGA7,PRPS2,LTBP2,NIPA1,RNF146,NF2,UPF3B,FOXM1,XYLT1,ERBB2,CCDC68,FAM198B,LPIN3,CYP26A1,RAD23A,PLCG2,SCN2A,EGLN3,MINPP1,DVL2,CTH,SIRT1,CPD,TMTC1,MBP,FIGNL1,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,NDST3,CMTM4,MAN2B2,COL9A3,GOLIM4,TM2D2,MACC1,RUSC2,GNE,BLVRB,PSMD10,NKRF,DSE,SIRPA,PPP2R3A,ABCD1,BUB1,FAIM,IGDCC4,FAH,DLGAP1,HMMR,CRB3,NR3C1,AMFR,LITAF,PPARA,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,BANK1,FAT4,SERPINA1,ZNF214,NMI,NETO2,PGRMC1,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,GAA,TMEM41B,PPFIBP2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IQCE,PRICKLE3,RGS3,STEAP2,AOX1,ATRNL1,MTMR11,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,HSPA12A,CASP9,NBPF3,TNS1,PIF1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,NKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,DGKQ,SLC25A27,C6orf106,KIF23,KIAA1161,PRRG4,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,RUNDC3B,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,B3GNT7,DDB2,ZNF84,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,ARMCX3,TRIP10,RPS6KA1,IQGAP1,BROX,RNF182,CD274,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,NIN,CMTM7,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,MLKL,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,TMCC3,SNTA1,PTEN,SGK3,ATP8B1,CNOT6L,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,GPLD1,AMMECR1,CSTF2,PGM2L1,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,CASP3,LTBP1,CPT2,CAMKK1,FLYWCH2,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,TSEN34,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,ZCCHC12,TSPAN6,ANKRD12,POF1B,RAB20,RP2,SLC39A10,PTPRE,RASGRP1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,ARHGEF19,NEIL1,ZNF114,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,ZNF432,OTUD1,CA2,LRIF1,ALS2CL,OXR1,GYLTL1B,RNF113A,MUM1L1,GNAS,XKRX,BCAR3,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,PROM2,SPC25,MORC4,TDRKH,ARHGEF16,LRRC45,SS18,FRYL,TWIST1,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,IGSF8,ERBB2IP,DUSP4,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,LIFR,PPP2R2D,ANXA3,POC1B,FRMD6,LRP4,AES,NOTUM,TRMT2B,IL17RB,MLPH,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,NR4A1,LRRC66,MBNL3,OGDHL,KLHL2,C2orf70,HNRNPH2,OTUB2,HOXB13,GEM,L1CAM,SNPH |
| 4.832e-11 | -23.75 | negative regulation of response to stimulus | biological process | GO:0048585 | 1309 | 206 | 16441 | 1675 |
SIGIRR,LTBP1,TXN,LGR4,DNAJC3,EPHA4,TAP1,NDRG2,PSME1,NENF,PDGFB,GRM5,SH3KBP1,PSMD1,IL6ST,RGS3,TSPAN6,DLG1,DUSP10,CRY2,SEMA3G,CTTN,PTPRE,CD55,TNIP1,ITCH,PBK,SLC35C1,EZR,F12,SLC25A5,ABR,OPTN,CXXC4,ENPP1,ANKRD6,TRAF3IP1,MADD,NKD1,NOD2,PRKCDBP,HDAC1,UNC5B,HSPB1,F2RL1,LZTS1,PRKAA2,SEMA6B,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,HLA-E,UBASH3B,RASA2,SOX9,PHLPP1,FBLN1,DHRS3,LMNA,MECOM,ITGA3,IGF1R,PIK3AP1,GATA2,VASN,DAPK1,PRKG1,SORL1,C10orf54,WNT3A,GPR161,MDFI,SOCS5,CYP26B1,MICB,AMER1,STRADB,NPHP3,PSMA4,RANBP9,G2E3,PLIN5,RASA1,ONECUT1,SEMA4D,NFKBIA,ITPR1,SH3BP4,NLRC5,EGFL7,NR4A2,YOD1,JAK3,SEMA3A,TOB1,IFI6,XDH,SPRED1,NF2,NLRX1,FOXM1,INPP5D,DDIT4L,PSME2,RGS20,TP53,IL27RA,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,IER3,PDGFA,CCND1,NOV,DACT1,BCL6,DAB2IP,TWIST1,IFIT1,LGMN,CDKN2D,DVL2,CHP1,SEMA3B,SULF2,CTH,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,PTGER4,PRKCQ,ERBB2IP,DUSP4,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,WFS1,TRABD2A,TLE1,NRG1,RGS14,CTHRC1,GCLM,PINK1,NKX3-1,LRP4,PSMD10,TGFBR1,AES,NOTUM,ETS1,GSTP1,HMGXB4,HLA-A,PPP2R3A,FZD6,CD109,CTNNBIP1,CARD8,ADORA1,ADRBK1,PTEN,BMP7,UBE2J1,BAX,TMBIM6,ERBB3,FAIM,SPRY2,TGIF1,RHOA,PSMB4,PLAUR,GCLC,GRIN1,LITAF,PPARA,PRICKLE1,STMN3,PELI3,BBS2,MAPK8IP1,ARHGAP24,HLA-B,BANK1,SCG2,TWSG1,TBX18,NMI,NR4A3,ARRB1,ITGAV,GPER1,NDFIP1,HIPK3 |
| 4.923e-11 | -23.73 | GSE3982_MAC_VS_BCELL_UP | MSigDB lists | GSE3982_MAC_VS_BCELL_UP | 194 | 51 | 17758 | 1761 |
CMAS,GNPDA1,VANGL1,ATP9A,CIT,CDCA8,PBX3,TGOLN2,PLXNA1,COX6C,PPP2R3A,SYTL2,TOP2A,CYP1A1,DPYSL2,GALNS,PAPSS1,TMEM51,KCNS3,BCL6,DIXDC1,TACSTD2,MTMR11,OAS3,TLN2,GFPT1,MPP1,CDA,ACO1,AK4,IDH1,ADRBK2,STX3,RHEB,CD83,GABARAPL1,FUCA1,FAM64A,TIMM8A,HNRNPH2,P4HA2,DBI,NR4A3,BMP1,VSIG10,ANXA9,FHL1,FZD5,ZMIZ1,ARSB,ACOT7 |
| 5.240e-11 | -23.67 | GNF2_CCNA2 | MSigDB lists | GNF2_CCNA2 | 67 | 27 | 17758 | 1761 |
HMMR,PLK1,ZWINT,CENPA,DLGAP5,HJURP,KIF20A,FOXM1,ASPM,CDC20,NDC80,CDCA8,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,KIF14,AURKA,CENPE,CCNB2,UBE2C,E2F8,ESPL1,MELK,CKS2 |
| 5.594e-11 | -23.61 | - | gene3d domains | 2.30.29.30 | 379 | 84 | 9988 | 1080 |
SPRED1,MTM1,NF2,SPTB,ARHGEF16,EPS8L2,ARHGEF10L,ACAP2,ELMO2,SHC3,DOK4,OSBPL3,RGS3,PLCG2,DAB2IP,RTKN2,EPB41L4B,TLN2,TIAM1,FRS3,AKT1,PLEKHO1,EZR,TNS1,ANLN,ADRBK2,ARHGEF26,ABR,IRS2,PLCG1,PLEKHG6,PLCH1,ARHGEF19,TRIOBP,PLEKHG1,SPTBN5,EPB41L4A,GAB1,FGD1,ARAP3,ARHGEF3,FRMD4A,ARHGEF11,TBC1D1,CIT,FRMD6,RASA2,EPS8,TEC,SBF1,PHLPP1,ARHGEF40,TNS3,ADRBK1,RALGPS2,ANKS1B,RANBP1,EXOC8,PLEKHF1,CADPS2,MYLIP,FARP2,EPB41L5,RASGRF1,ARAP2,PLEKHA6,ARHGEF28,SPATA13,SNTB1,MAPK8IP1,RASA1,FRMD4B,ARHGAP24,DGKH,SWAP70,PLEKHH2,FGD6,PLD1,TBC1D4,AFAP1,ARHGEF9,DEF6,DOCK9,ARHGEF4 |
| 5.820e-11 | -23.57 | ovary | COSMIC cancer mutations | ovary | 15550 | 1618 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,CD82,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,HABP4,SDC4,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,H1FX,NRP2,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,DAPK1,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,PLEKHF1,ADAM15,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,C2orf70,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.842e-11 | -23.56 | intracellular signal transduction | biological process | GO:0035556 | 1835 | 270 | 16441 | 1675 |
RET,NRG2,IL18,PSME1,PJA2,CA8,CENPN,CARD10,NCS1,CALM2,DAPK2,PSMD1,CTGF,IL31RA,PIK3CA,PIK3CD,RCAN3,TIAM1,CASP9,PRKAR2B,AGO4,SAV1,ARF4,ABR,CARHSP1,PLCG1,LIMK1,PLK2,NOD2,EIF4EBP2,ARF6,HSPB1,GAB1,FGD1,DDX58,NUAK1,DGKQ,SOX9,RAB23,MERTK,TNFRSF19,TFAP4,RALGPS2,FLRT3,FAM13B,DAPK1,MAP3K9,PRKG1,PIKFYVE,NCAM1,MAST4,DGKG,NUP85,RIMS2,SOCS5,PRODH,STAT4,CALM1,ERO1A,ELK1,PSMA4,RASA1,STK17A,DGKH,PRKAG2,ITPR1,STK39,MAP3K5,NDE1,ARPC2,IFIH1,DOCK9,ARHGAP11A,SPRED1,TRIP10,RALBP1,INPP5D,RPS6KA1,IQGAP1,NUF2,BCL2L1,PRKACA,ZNF385B,EPS8L2,CDH1,SP100,DOK4,CDKN1B,DAB2IP,PDE4D,ARL4D,RAB27B,RASGEF1A,DOCK4,RIPK2,PRKCQ,ATP1B1,RAB38,ASB13,ITPR3,IRS2,JAK1,STK26,AXL,NRG1,RGS14,MAPK12,ARHGEF3,TNRC6C,NKX3-1,DEPDC1,CENPI,EPS8,ARL4C,PKN1,FGF19,TEAD3,DIRAS3,E2F7,PTEN,SGK3,BAX,TMBIM6,ADAM15,MAPK11,ERBB3,NCOA2,FARP2,AMOTL2,RASGRF1,ARHGEF28,ZWINT,ARAP2,RAPGEF2,PIK3R1,GRIN1,DIAPH2,FOS,FGFR2,GRIN2D,CENPE,ITGAV,LRRK1,MELK,MYL9,CASP3,NDC80,ITPR2,PDGFB,SPTB,RAB15,RPS6KA2,SHC3,SIVA1,AKR1B1,DUSP10,RAB20,MYH14,CTTN,RASGRP1,CYP1B1,PLK1,CENPA,MCTP1,ITCH,EZR,ARHGDIB,ARFRP1,STK17B,RHEB,PLCH1,CAB39,PIK3C2B,MYL12B,PRKAA2,ARAP3,BMF,RASA2,PDCL,ASB9,CALM3,NCKAP1,RAB6A,TEC,PHLPP1,IGF1R,MDFIC,SELK,PLCB2,CCDC88A,MDFI,CORO2A,STRADB,RASGRP2,MAPKAPK2,BCAR3,PHLPP2,NFKBIA,RHOBTB2,PLD1,JAK3,NF2,SPC25,IL15,FOXM1,PSME2,TP53,ERBB2,CCDC68,MRAS,BCAP31,ARHGEF16,IER3,PDGFA,SS18,KIF14,PLCG2,BCL6,SCN2A,F2R,DVL2,CHP1,FRS3,SIRT1,MAP3K3,AKT1,CDC20,PTGER4,DUSP4,CD40,DOCK5,CASP4,MAP3K6,SOCS3,ARHGAP35,DNAJC10,STK38,IRF7,SPTBN5,ZMAT1,PINK1,ADGRG1,ARHGEF11,CIT,CDCA8,PSMD10,TGFBR1,SGK1,BUB1,IQGAP3,SYK,HES1,RAB3B,RHOA,PSMB4,DEPDC4,NR4A1,DGKE,MAPK8IP1,PRDX4,ARHGAP24,FAT4,SCG2,RND3,NMI,RAP2C,GEM,ARHGEF9,ZBTB33,ARHGEF4 |
| 5.925e-11 | -23.55 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | 111 | 36 | 17758 | 1761 |
PRSS8,GRHL2,MACC1,ST14,TSC22D3,FXYD3,ESRP1,F11R,PRRG4,CDS1,ELF3,SCNN1A,CDH1,ZFP36,FOSB,AIM1,CDH3,TACSTD2,MYO5B,SSH3,KLK5,MBNL3,LITAF,SLC11A2,KLK6,EPHA1,PPP1R14C,EPN3,ATP1A1,KCNK1,SPINT2,OVOL1,ZNF165,MAL2,EPB41L4A,PROM2 |
| 6.073e-11 | -23.52 | MANALO_HYPOXIA_UP | MSigDB lists | MANALO_HYPOXIA_UP | 201 | 52 | 17758 | 1761 |
ENO2,ZNF395,CDKN1C,NUAK1,HLA-E,ARL4C,COL18A1,NENF,ITPR2,TRIB2,PDGFB,PHLDA1,IER3,RPS6KA2,FAM46A,CYP4F11,RGS3,N4BP3,PLCG2,OPN3,BCL6,LIMCH1,EGLN3,CLIP2,MAST4,HES1,PGM1,ALDH2,PLEKHO1,AK4,DIAPH2,TNS1,LOXL2,LEPR,GLCE,PTPRF,PGF,HLA-B,ENPP1,PLOD2,CDK19,P4HA2,PELI2,AXL,ALPK3,TLE1,KLF11,GRAMD1C,MAFF,AFAP1,ABCA1,EGLN1 |
| 6.379e-11 | -23.48 | LIM_MAMMARY_STEM_CELL_DN | MSigDB lists | LIM_MAMMARY_STEM_CELL_DN | 409 | 84 | 17758 | 1761 |
SIGIRR,SLC35D2,ILDR1,NLRX1,ST14,CPT2,HDAC11,PPFIBP2,ERBB2,TDRKH,PSME1,SYTL4,DENND2D,TRIM68,ARHGEF16,EPCAM,AP1M2,CDH1,GRHL1,ZDHHC12,ALDH1A3,CLDN4,MYH14,DLG3,TRAM1,SULT2B1,SNX10,SCYL3,SULF2,MYO5B,ENPP4,GCA,SSH3,CAMSAP3,CLCN3,HTATIP2,ATP1B1,ALDH5A1,IDE,RBM47,CDK19,RAB11FIP1,ARRDC1,COBL,CMAS,ESRP1,PYROXD2,RASSF7,PSMD10,FBXO6,ANO9,PKN1,LGALS3BP,ELF3,DTX3L,ADD3,MLPH,CA2,LYPD3,BDH1,TFAP2A,SORL1,ERBB3,SLC16A5,TPCN1,NCOA2,MCCC2,PVRL4,OPLAH,SHMT1,SLC37A1,CRB3,CORO2A,SPATA13,C1GALT1C1,GRTP1,MFSD7,DHX32,PTPRF,TMEM54,TJP3,FAAH,NAT1,PPM1H |
| 6.713e-11 | -23.42 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | 315 | 70 | 17758 | 1761 |
ARHGAP11A,CCNE2,DLGAP5,FOXM1,PTTG1,RET,BARD1,STIL,FAM46C,CENPN,FANCI,UBE2T,CEP78,PLK4,GLB1L2,ARMCX6,MYBL1,SEMA3B,PLK1,PPIF,LOC81691,CELSR2,FIGNL1,SLC39A8,PBK,CDCA2,NUSAP1,PKMYT1,ANLN,CDK1,COL12A1,PRIM1,TMEM164,RBL1,ZNF367,LRIG1,DHTKD1,GLA,E2F8,CENPI,CIT,KIF23,IL17RB,TFAP4,TOP2A,E2F7,LYPD6,SGK3,BUB1,IQGAP3,MPHOSPH9,NUP85,ZWINT,ASPM,MICB,MYBL2,CCDC34,GGH,KIF11,DHRS2,CDCA5,CDCA7L,FAM83D,AURKA,WDR62,CCNB2,UBE2C,NCAPG2,ESPL1,MELK |
| 6.808e-11 | -23.41 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | 122 | 38 | 17758 | 1761 |
DLGAP5,SPC25,DEPDC1,CKAP2,PTTG1,CDCA8,KIF23,NUF2,FAM198B,CCNB1,FBLN1,CENPN,LBR,TOP2A,UBE2T,RANBP1,NEK2,BUB1,SEMA3B,SULF2,HMMR,CENPA,KIF20A,ASPM,CDC20,MYBL2,NUSAP1,ANLN,BORA,KIF11,H2AFV,CDK1,FAM64A,WIPI1,CCNB2,UBE2C,E2F8,MELK |
| 7.408e-11 | -23.33 | negative regulation of signal transduction | biological process | GO:0009968 | 1023 | 169 | 16441 | 1675 |
SIGIRR,LTBP1,LGR4,NDRG2,PSME1,GRM5,SH3KBP1,PSMD1,IL6ST,RGS3,TSPAN6,DLG1,DUSP10,CRY2,CTTN,PTPRE,TNIP1,ITCH,PBK,SLC35C1,EZR,SLC25A5,OPTN,CXXC4,ENPP1,ANKRD6,TRAF3IP1,MADD,NKD1,NOD2,PRKCDBP,HDAC1,UNC5B,HSPB1,F2RL1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,RASA2,UBASH3B,SOX9,PHLPP1,FBLN1,DHRS3,LMNA,MECOM,ITGA3,IGF1R,PIK3AP1,GATA2,VASN,DAPK1,SORL1,WNT3A,GPR161,MDFI,SOCS5,CYP26B1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,G2E3,PLIN5,RASA1,ONECUT1,NFKBIA,ITPR1,SH3BP4,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,SPRED1,NF2,FOXM1,NLRX1,INPP5D,DDIT4L,PSME2,RGS20,TP53,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,IER3,CCND1,NOV,DACT1,BCL6,DAB2IP,TWIST1,LGMN,CDKN2D,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,PRKCQ,ERBB2IP,DUSP4,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,WFS1,TRABD2A,TLE1,NRG1,RGS14,CTHRC1,GCLM,PINK1,NKX3-1,LRP4,PSMD10,TGFBR1,AES,NOTUM,GSTP1,PPP2R3A,FZD6,HMGXB4,CD109,CTNNBIP1,CARD8,ADRBK1,PTEN,BMP7,BAX,TMBIM6,ERBB3,FAIM,SPRY2,TGIF1,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,PELI3,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 7.462e-11 | -23.32 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 245 | 59 | 17758 | 1761 |
LTBP1,UGP2,ADD1,ZNF395,SERPINE2,IGFBP6,HEBP1,TMX4,SDC4,ARL4C,MORC4,COL18A1,IL27RA,NTAN1,CARD10,NRP2,M6PR,APOBEC3B,TNS3,CYR61,GATA2,CTSC,CD9,KCNS3,FXYD5,SGK1,OSTF1,EPB41L4B,PTPRE,GAD1,S100A13,SCN3A,FAM69A,HES1,PDGFC,TGIF1,COL6A2,ELK3,MMD,PLSCR1,NR3C1,PTPRU,PBK,SEPT6,PRKAR2B,LOXL2,ADRBK2,IRS2,PGF,CARHSP1,JAK1,DTX4,ARRB1,CLMN,CTSA,MAP3K5,MAFF,CYBRD1,PCSK5 |
| 7.849e-11 | -23.27 | regulation of hydrolase activity | biological process | GO:0051336 | 1252 | 198 | 16441 | 1675 |
CASP3,PPP4R4,EPHA4,RET,ARFGEF1,DNAJB11,F11R,PSME1,ITPR2,DENND2D,CALM2,ARHGEF10L,SIPA1L2,CTGF,NPNT,ARHGEF37,RGS3,CRY2,RP2,SLC39A10,TIAM1,RASGRP1,ACVR1C,CASP9,ARHGDIB,PRKAR2B,POR,ARF4,ABR,ARHGEF26,EDNRA,PLCG1,PLEKHG6,NEIL1,ARHGEF19,MADD,AGFG2,SERPINB6,SERPINI1,RAP1GAP,FGD1,ARAP3,LMTK3,PPP1R2,SERPINE2,TBC1D1,NUAK1,BVES,ITGA6,RASA2,CALM3,FBLN1,TFAP4,RALGPS2,CYR61,SNX18,RINL,RANBP1,FAM13B,TBCD,DAPK1,PRKG1,SORL1,WNT3A,PLCB2,ALS2CL,PPP6R1,TBC1D8B,CALM1,SPATA13,SCRIB,EPHA1,PLIN5,RASA1,FAS,RASGRP2,GNAS,BCAR3,SEMA4D,ITPR1,SH3BP4,FGD6,ATP1B3,MAP3K5,SERPINB1,IFI6,XDH,EGLN1,DOCK9,PROM2,ARHGAP11A,SPRED1,RPS6KA1,IQGAP1,PSME2,CAST,RALBP1,PTTG1,RGS20,TP53,ERBB2,PRKACA,BCAP31,ARHGEF16,SYTL2,EPS8L2,APLP2,ST5,ACAP2,SH3BP1,BCL6,CDKN1B,DAB2IP,IFIT1,TMEM64,OAS3,RASGEF1A,EGLN3,DLG3,CDKN2D,F2R,GM2A,CHP1,DOCK4,SIRT1,PPIF,CAMSAP3,TIMP2,AKT1,SLC11A2,ATP1B1,PKMYT1,ITPR3,CD40,DOCK5,ARHGAP35,DNAJC10,PPP2R5A,NGFRAP1,CORO1C,SIPA1L1,PLEKHG1,EFNA5,RGS14,PPP2R2D,MAPK12,ARFGEF3,DENND5B,ARHGEF3,PINK1,NKX3-1,PCOLCE,SORT1,DEPDC1,ARHGEF11,DAP,SBF1,ARHGEF40,AIP,TIPRL,PPP2R3A,SH2D4A,CD109,CARD8,ADRBK1,CTSC,LLGL2,CST3,BAX,TMBIM6,IQGAP3,SPRY2,FARP2,RASGRF1,ARAP2,RHOA,ARHGEF28,PLSCR1,RAPGEF2,PLAUR,FURIN,STMN3,COL7A1,GRTP1,LEPR,GPLD1,ARHGAP24,TIMP3,SERPINA1,FGFR2,SPINT2,ARRB1,GPER1,TBC1D4,CPEB2,ARHGEF9,RAB3IL1,ARHGEF4 |
| 8.323e-11 | -23.21 | GNF2_CDC20 | MSigDB lists | GNF2_CDC20 | 55 | 24 | 17758 | 1761 |
HMMR,PLK1,ZWINT,KIF20A,DLGAP5,FOXM1,ASPM,CDC20,PTTG1,NDC80,CDCA8,NUSAP1,KIF11,CDK1,TOP2A,PLK4,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,MELK,CKS2 |
| 8.648e-11 | -23.17 | cell development | biological process | GO:0048468 | 1717 | 255 | 16441 | 1675 |
EXPH5,MYL9,CASP3,EMX1,UGT8,EPAS1,CUL4B,RET,EPHA4,HEXB,CACNA2D2,ARFGEF1,NRG2,MPP5,PSME1,F11R,PLXNA1,CCNB1,DNER,FAM101B,SDC1,CACNB4,PDGFB,SPTB,TMC1,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,IMPAD1,PAQR5,DLG1,TRPC1,NTN4,CTTN,MYH14,SEMA3G,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,SMARCA2,CELSR2,CASP9,EZR,TFAP2C,LOXL2,ARF4,ARHGEF26,EDNRA,DPYSL3,HS6ST1,PLCG1,MAP2,LIMK1,TMOD2,UNC5B,F2RL1,MYL12B,SEMA6B,SCN5A,RUNX2,CDKN1C,BVES,RASA2,SOX9,ETV5,CALM3,CNTNAP2,SLC1A3,MERTK,KIAA1161,LMNA,IGF1R,FRY,CYR61,GATA2,FLRT3,MEGF8,COL6A1,PRKG1,CACNA1D,NCAM1,WNT3A,DGKG,PAQR7,EPB41L5,DPYSL5,REC8,RGMB,CALM1,SCRIB,EPHA1,ANTXR1,NFIB,PSMA4,RANBP9,STX3,RASA1,CDK5R1,PTPRF,ONECUT1,PVRL2,SEMA4D,MFSD2A,MATN2,FAM83D,CLMN,AURKA,PITPNA,NR4A2,GDF11,ARPC2,JAK3,HOOK1,SEMA3A,RARG,KLF7,EHD1,SPRED1,GRHL2,IL15,ST14,PSME2,RPS6KA1,IQGAP1,HDAC11,COL18A1,ERBB2,BCL2L1,PRKACA,PDGFA,CDH1,ARTN,DACT1,KIF14,FRYL,LHX6,BCL6,TWIST1,DAB2IP,EPHB4,PDE4D,ACSL4,RASGEF1A,DLG3,ETV4,SULF2,SEMA3B,FRS3,CAMSAP3,COL6A2,AKT1,FZD4,S100A4,SLC11A2,PRKCQ,PYGO1,ALCAM,MYL12A,DAG1,FZD7,ARHGAP35,EPHA10,IRS2,JAK1,BFSP1,SHROOM3,CORO1C,AXL,SLC9A6,PTBP3,KLF5,EFNA5,SPTBN5,NRG1,LIFR,COBL,WASF3,CTHRC1,COL9A3,ARHGEF11,CIT,FRMD6,LRP4,SDC4,PBX3,PSMD10,COL4A5,GDF15,TGFBR1,PLPPR4,SPR,FGF19,EFNB1,SIX4,NRP2,NEO1,KIF5B,IGSF9,PTEN,CDK16,BMP7,CST3,TFAP2A,CD9,UBE2J1,BAX,ADAM15,SGK1,ATP8B1,ERBB3,SGCB,S100A6,FARP2,RASGRF1,HES1,B3GNT2,ARHGEF28,RHOA,PSMB4,FMN1,ASPM,RAPGEF2,GRIN1,STMN3,DIAPH2,C1GALT1C1,RUNX3,YES1,FNDC3A,BBS2,CNTNAP1,PITX2,FAT4,FGFR2,SPINT2,RAP2C,NR4A3,RYK,PGRMC1,GRIN2D,HOXB13,ITGAV,LRRK1,PLOD3,FZD5,OSR1,SOX8,L1CAM,RGMA |
| 8.843e-11 | -23.15 | negative regulation of phosphorylation | biological process | GO:0042326 | 388 | 82 | 16441 | 1675 |
CASP3,SPRED1,NF2,FOXM1,DNAJC3,CTDSPL,NDRG2,CCNB1,IER3,CALM2,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,TWIST1,PDE4D,CDKN2D,CTDSP2,CHP1,PLK1,SIRT1,PPIF,TNIP1,AKT1,ITCH,PBK,EZR,PRKAR2B,DUSP4,DAG1,SOCS3,IRS2,ENPP1,DNAJC10,PTPRJ,PPP2R5A,CORO1C,STK38,TRAF3IP1,RGS14,HSPB1,F2RL1,PINK1,CDKN1C,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,FBLN1,GSTP1,MECOM,CD109,TFAP4,IGF1R,PTEN,BMP7,BAX,SORL1,SPRY2,SOCS5,RHOA,CALM1,PPARA,EPHA1,RANBP9,MAPK8IP1,CDK5RAP1,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,LRRK1,GPER1,UBE2C,HIPK3,PKIA,XDH |
| 9.238e-11 | -23.11 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | 145 | 42 | 17758 | 1761 |
CCNE2,TXN,DLGAP5,HJURP,FOXM1,CENPI,PTTG1,NDC80,CDCA8,CCNB1,STIL,CENPN,TOP2A,APOBEC3B,KIF14,NEK2,BUB1,CKS2,HMMR,PLK1,CENPA,ZWINT,KIF20A,ASPM,ITCH,CDC20,MYBL2,NUSAP1,PKMYT1,KIF11,H2AFV,CDK1,FAM64A,AURKA,DONSON,CENPE,NCAPG2,CCNB2,UBE2C,E2F8,ESPL1,MELK |
| 9.302e-11 | -23.10 | MODULE_139 | MSigDB lists | MODULE_139 | 73 | 28 | 17758 | 1761 |
DPYSL5,GCA,BCAM,BLVRB,TFAP2C,TP53I11,CRABP2,AIF1L,PDGFB,ARHGEF16,CYB5A,SYTL2,ELF3,EPCAM,SCNN1A,MLPH,CDH1,TJP3,BMP7,BDH1,SPINT2,CLDN4,ANXA9,MAL2,ERBB3,SULT2B1,ISOC1,OCLN |
| 9.457e-11 | -23.08 | cell morphogenesis involved in differentiation | biological process | GO:0000904 | 857 | 147 | 16441 | 1675 |
MYL9,CASP3,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,FAM101B,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,SHC3,DPYSL2,DLG1,TRPC1,NTN4,MYH14,BTBD3,TIAM1,RASGRP1,ATL1,CELSR2,CASP9,EZR,LOXL2,ARHGEF26,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,MYL12B,SCN5A,BVES,RASA2,SOX9,CALM3,SLC1A3,MERTK,IGF1R,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,EPB41L5,DPYSL5,RGMB,CALM1,SCRIB,EPHA1,ANTXR1,RANBP9,NFIB,PSMA4,RASA1,CDK5R1,SEMA4D,MATN2,FAM83D,PITPNA,NR4A2,ARPC2,JAK3,SEMA3A,KLF7,SPRED1,GRHL2,ST14,PSME2,RPS6KA1,COL18A1,ERBB2,PDGFA,ARTN,KIF14,DACT1,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,FRS3,SEMA3B,COL6A2,FZD4,S100A4,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,ARHGAP35,IRS2,EPHA10,JAK1,AXL,SLC9A6,SPTBN5,EFNA5,NRG1,COBL,COL9A3,ARHGEF11,FRMD6,LRP4,PSMD10,TGFBR1,COL4A5,PLPPR4,SPR,EFNB1,FGF19,NRP2,NEO1,KIF5B,PTEN,BMP7,ADAM15,ERBB3,S100A6,FARP2,HES1,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,FMN1,RAPGEF2,GRIN1,C1GALT1C1,YES1,CNTNAP1,FGFR2,SPINT2,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,PLOD3,L1CAM,RGMA |
| 9.568e-11 | -23.07 | GNF2_SMC2L1 | MSigDB lists | GNF2_SMC2L1 | 32 | 18 | 17758 | 1761 |
HMMR,ZWINT,FOXM1,ASPM,CDC20,NDC80,MYBL2,CDCA8,NUSAP1,KIF11,CDK1,PRIM1,TOP2A,BUB1,CENPE,CCNB2,ESPL1,CKS2 |
| 9.980e-11 | -23.03 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 349 | 76 | 16441 | 1675 |
CASP3,SPRED1,NF2,FOXM1,DNAJC3,CTDSPL,NDRG2,CCNB1,CALM2,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,TWIST1,PDE4D,CDKN2D,CTDSP2,CHP1,PLK1,SIRT1,TNIP1,AKT1,ITCH,PBK,EZR,PRKAR2B,DUSP4,DAG1,SOCS3,ENPP1,DNAJC10,PTPRJ,CORO1C,STK38,TRAF3IP1,RGS14,HSPB1,F2RL1,PINK1,CDKN1C,UBASH3B,PSMD10,CALM3,PKN1,TRIB2,FBLN1,GSTP1,MECOM,CD109,TFAP4,IGF1R,PTEN,BMP7,BAX,SORL1,SPRY2,SOCS5,CALM1,EPHA1,RANBP9,MAPK8IP1,CDK5RAP1,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,LRRK1,GPER1,UBE2C,HIPK3,PKIA,XDH |
| 1.009e-10 | -23.02 | response to stimulus | biological process | GO:0050896 | 7571 | 895 | 16441 | 1675 |
ADD1,IL15RA,AK7,SLC25A13,DNAJC3,RET,FBXO2,NRG2,IL18,MORF4L2,DPP8,CA8,BARD1,CMTM6,CARD10,GRM5,CALM2,DAPK2,WEE1,PSMD1,UBE2T,CYP2S1,ALDH1A3,KLF3,CLDN4,CRY2,SEMA3G,TINAGL1,PIK3CD,MANF,TIAM1,TIPARP,APOBEC3G,ERAP2,TNIP1,CDA,PRKAR2B,LOXL2,F12,RNF19B,CYP4F3,ARF4,ABR,PIAS3,PGF,ENPP1,CARHSP1,PLCG1,DNM1L,LIMK1,ATP7B,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NUAK1,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ATG4A,ELF3,MARCH8,TFAP4,MEGF8,RIMS3,FLRT3,FAM13B,RANBP1,MAP3K9,ALPK1,MYDGF,PANX2,NCAM1,DGKG,ULBP2,NDUFA12,NUP85,PAQR7,REC8,SALL4,STAT4,ERO1A,ELK1,NPHP3,PSMA4,GNA11,CYB5A,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,RAET1L,AURKA,MDH1,STK39,GDF11,NDE1,ARPC2,NUP58,TMEM173,EGLN1,DOCK9,ARHGAP11A,NQO1,PAPSS2,INPP5D,ACTR8,CD82,PTTG1,NUF2,IL13RA1,GRK6,MGST2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,CDH1,SP100,SH3BP1,DACT1,RTKN2,ACSL4,LRP11,ARL4D,DLG3,RAB27B,RASGEF1A,CDKN2D,ETV4,MX1,ENPP4,SEC61B,COL6A2,RIPK2,APOBEC3D,FZD4,RAB38,XRCC6BP1,IRS2,ALDH3B1,CDK19,SHROOM3,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,NKX3-1,TNRC6C,SDC4,HABP4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,ETS1,GSTP1,TIPRL,PDIA4,SGPL1,NEO1,CTNNBIP1,DTX3L,DIRAS3,CXCL16,ADD3,ITGB8,CTSC,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,PARP9,AMOTL2,OPLAH,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,AK4,NEURL1B,CNTNAP1,PITX2,HCP5,PLOD2,RAB11FIP2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,OSER1,ITGAV,CENPE,HMGA1,CMPK2,OSR1,USF2,WDR45B,CYBRD1,MYL9,SIGIRR,BCAM,EPAS1,CUL4B,EPHA4,NDC80,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,TP53I11,HDAC6,PDGFB,SDC1,SPTB,FANCI,SUSD2,CPNE2,RPS6KA2,NPNT,SHC3,IL6ST,PAPSS1,MITF,ABCA2,DUSP10,NTN4,SCARA3,S100A13,PLK1,THRB,CD55,KCNIP3,MCTP1,CELSR2,CITED4,NFE2L1,CR2,EZR,KLK6,ARFRP1,PRKRA,IDH1,SESN1,CDK1,RHEB,OPTN,DPYSL3,KDM4D,PLCH1,KCNMB4,MAP2,WIPI1,PIK3C2B,PIEZO1,MYL12B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,DNAJB2,RASA2,HLA-F,PDCL,RAB6A,NCKAP1,CNTNAP2,FBLN1,DHRS3,IL18R1,ANO1,IGF1R,GATA2,KIF13B,SELK,MDFIC,AHCY,PIM1,WNT3A,PLCB2,ABCC1,CYP26B1,DPYSL5,RGMB,CORO2A,STRADB,SCRIB,EIF2AK1,TCF7,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,NLRC5,LTBP2,PLD1,ATP1B3,SEMA3A,IFI6,RNF146,USP43,NF2,UGP2,FOXM1,XYLT1,TMX4,TP53,CCDC68,ERBB2,SLC7A2,STIL,EMP2,BCAP31,CYP26A1,RAD23A,IER3,TTC21B,PDGFA,ATP6V0B,PLCG2,SRR,BCL6,CDH3,NOTCH3,OAS3,SCN2A,LMAN1,EGLN3,CTDSP2,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,MBP,ERLEC1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,DAG1,ATP13A2,DUOX1,TAPBP,DNAJC10,PTPRJ,ATP1A1,IDE,ABHD12,RBL1,PTK7,STK38,EFNA5,IRF7,LTA4H,CMTM4,ZMAT1,COL9A3,PINK1,CPEB4,CD63,ADGRG1,DAP,SWI5,CDCA8,GABRG2,SELL,PSMD10,GDF15,CRABP2,AIP,DNAJB9,FZD6,PPP2R3A,SIRPA,NRP2,M6PR,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,TSPAN13,KLF9,SYK,ATP2B1,GCNT1,HES1,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,LITAF,PPARA,MAML2,GGH,PELI3,BCAR1,BBS2,TXNDC11,MAPK8IP1,DGKE,CD83,PRDX4,SERPINA1,FAT4,TWSG1,SCG2,NAT1,NMI,PGRMC1,ICOSLG,NDFIP1,TBC1D4,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,TAP1,PSME1,PLXNA1,CAMK1D,CCNB1,PJA2,VASH1,SLC20A1,CENPN,NCS1,TYMP,CYP1A1,SESN3,CTGF,STIM1,ELMO2,ZFP36,IL31RA,FOSB,STEAP2,PIK3CA,AOX1,IRF2,ATRNL1,TACSTD2,RCAN3,METAP2,LAMP2,SPATA18,ACVR1C,PBK,CASP9,SLC35C1,AGO4,PIF1,SAV1,ZFAND5,POR,AHRR,PLK2,NKD1,EIF4EBP2,NFKBIZ,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,KIF23,SLC1A3,TNFRSF19,TSPAN7,PSIP1,MESDC2,MECOM,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,RPL39,PPP4R1,TPST1,DAPK1,PRKG1,OPN3,SORL1,CD70,TNFRSF12A,OSTF1,CACNA1D,PIKFYVE,MAST4,GPR161,RIMS2,SOCS5,EPB41L5,GFPT1,DDB2,PRODH,MICB,CALM1,AMER1,ANO6,NPC2,EPHA1,ANTXR1,NFIB,RASA1,FAS,DGKH,MMP15,GABRD,PRKAG2,PELI2,CSNK1G1,MATN2,NR4A2,CABIN1,MAP3K5,IFIH1,EHD1,PLA2G4A,SPRED1,SLC2A4,TCTN2,REPS2,NLRX1,S100A11,TRIP10,THRA,RPS6KA1,IQGAP1,RALBP1,FTH1,CD274,BCL2L1,SNN,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,APLP2,NOV,ACAP2,DOK4,CNNM4,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,LGMN,TSPAN1,SULT2B1,NR2C1,MED30,GPX4,SEMA3B,ATG4D,DOCK4,PRKCQ,SLC11A2,ATP1B1,RAD17,PYGO1,ASB13,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,JAK1,DDOST,PPP2R5A,STK26,NGFRAP1,TSPAN18,SLC27A1,NRG1,NR3C2,CBX7,DENND5B,ARHGEF3,IGFBP6,DEPDC1,CENPI,EPS8,ARL4C,HERC5,APOBEC3H,FBXO6,SEPP1,EFNB1,FGF19,LGALS3BP,TEAD3,ADGRB2,HLA-A,RASSF8,E2F7,FAM111A,GNB5,PTEN,FUT8,SGK3,CD9,ATP8B1,SLC44A2,ERBB3,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARAP2,ZWINT,SHMT1,B3GNT2,ARHGEF28,ALDH2,MPP1,FURIN,PARP4,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,NUCB1,TIMP3,FGFR2,ABCB1,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,ARSB,CPEB2,MELK,RGMA,EMX1,LTBP1,CASP3,UGT8,CACNB4,DNER,SLC8B1,KREMEN1,TMC1,TRIM68,SH3KBP1,PTCHD4,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,SIVA1,TSPAN6,DPYSL2,DLG1,AKR1B1,TRPC1,RAB20,MYH14,CTTN,PTPRE,RASGRP1,SP5,LAMP3,CYP1B1,NLRP4,TRIM8,CENPA,ITCH,USP18,ARHGDIB,ROR1,STK17B,ADRBK2,EDNRA,MDK,CXXC4,NEIL1,ARHGEF19,GPRC5B,HPSE,MADD,CAB39,ADIPOR1,NRGN,RAP1GAP,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,SERPINE2,ETV5,ASB9,ABCG2,CALM3,TEC,PHLPP1,CA2,KCNN4,COL6A1,DIAPH2-AS1,C10orf54,HLA-C,ZRANB1,SLC12A2,CCDC88A,MDFI,ELK3,OXR1,BTN3A2,VWA1,HMG20B,PDE5A,RANBP9,FECH,GNAS,BCAR3,ONECUT1,PLPP3,TMEM30A,CGREF1,NFKBIA,CDCA5,SH3BP4,RHOBTB2,YOD1,PITPNA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,KLF7,GAS2L1,DYNLRB1,SLC25A24,SORBS1,SPC25,IL15,PSME2,PDIA5,COL18A1,IL27RA,MRAS,ARHGEF16,SS18,ARTN,CYP4F11,KIF14,GOT1,TWIST1,DIXDC1,RPN2,EPB41L4B,F2R,PDIA6,FRS3,CHP1,MAP3K3,PTPRU,ERBB2IP,DUSP4,CD40,FANCE,DOCK5,MAP3K6,CASP4,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,CYP2U1,LIFR,ABCA1,ANXA3,GCLM,SORT1,ARHGEF11,CIT,LRP4,TGFBR1,AES,COL4A5,NOTUM,HMGXB4,HDAC9,KIF5B,IL17RB,TOP2A,ADORA1,ADRBK1,BMP7,TOX2,IQGAP3,MYO5A,PGM1,RAB3B,NR4A1,DEPDC4,GCLC,RC3H2,RGCC,RUNX3,LEPR,CTSL,ARHGAP24,HLA-B,SWAP70,RND3,DHRS2,PRCP,CTSV,RAP2C,DTX4,ARRB1,UACA,HOXB13,GEM,SOX8,PLOD3,AHR,L1CAM,CD33,ABCG1 |
| 1.018e-10 | -23.01 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 490 | 95 | 17758 | 1761 |
GAS2L1,MYL9,DYNLRB1,FOXO6,BCAM,UPF3B,NF2,PKP2,IL27RA,TEX2,TGOLN2,MGAT5B,NUP62CL,BARD1,MNS1,RAB15,AP1M2,ACAP2,CTGF,ZDHHC12,KIF14,ENPP5,MITF,SUN3,NOTCH3,TMEM37,SCARA3,MED30,CTH,SEPHS1,SEMA3B,MYO5B,GCA,ORAI2,FBXL16,SERTAD4,UTRN,TNS1,ARHGDIB,PPP1R14C,DOCK5,PTGFRN,ALCAM,ALDH3B1,CARHSP1,ALDH5A1,CDK19,PTK7,WFS1,PEX2,RAB11FIP1,EIF4EBP2,PCOLCE,ZNF395,DCAF7,TMEM55B,ZCCHC24,GNE,C6orf106,DSE,SLC25A43,FBLN1,MARCH8,C16orf74,TNS3,ADD3,CYR61,CDK16,LIMCH1,MDFIC,RIMS2,FAH,GFPT1,RAB3B,ARAP2,OGDHL,MYBL2,STMN3,FBXO9,VEZT,AIF1L,ANTXR1,ENDOD1,FAM64A,H1F0,DHRS2,CDCA7L,MATN2,RAP2C,SPCS3,CENPE,CEP41,ARSB,NDFIP1,DIS3L |
| 1.080e-10 | -22.95 | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 427 | 86 | 17758 | 1761 |
SUN1,GAA,PDIA5,SLC20A1,DDR1,TNFSF9,BCAP31,CHPF,APLP2,PSMD1,RGS3,ZFP36,IL6ST,KLF3,FOSB,ABCA2,RPN2,EPHB4,LGMN,PDIA6,NAGA,SEMA3B,TIMP2,IGSF8,SLC11A2,LHFPL2,DAG1,POR,FZD7,SOCS3,TAPBP,ATP1A1,GPRC5B,DDOST,ABHD12,P4HA2,AXL,BMP1,AGFG2,NFKBIZ,GLA,GRN,RUSC2,PDIA3,COL4A5,ADAMTSL4,NRP2,SGPL1,WWP2,CD109,GNS,ITGA3,IGF1R,KCNN4,VASN,CALD1,RRBP1,CD9,SLC44A2,NCEH1,MAST4,CKAP4,IGSF3,ABCC1,SUN2,TGIF1,PGM1,PCDH1,RGMB,BCL9,C1GALT1C1,TTC7A,FOS,TP53INP2,NFIB,PTPRF,SLC6A6,RPL12,TIMP3,TWSG1,MATN2,PCDH19,PER3,ZMIZ1,COL16A1,DCBLD1 |
| 1.100e-10 | -22.93 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | 198 | 51 | 17758 | 1761 |
SUN1,CD99,CASP3,MTM1,TXN,DLGAP5,LGALS3,CDCA8,KIF23,TOP2A,CDKN2C,WEE1,CA2,UBE2T,SIVA1,PLK4,NEK2,BUB1,TAGLN2,IQGAP3,SNX10,CKS2,SYPL1,CENPA,KIF20A,IFITM3,ASPM,NR4A1,S100A4,CDC20,LITAF,NUSAP1,GGH,PDK3,ANLN,CCNF,DOCK5,KIF11,CDK1,PRDX4,GABARAPL1,PRIM1,GALNT3,H1F0,RBL1,DCK,DBI,AURKA,GEM,CCNB2,E2F8 |
| 1.104e-10 | -22.93 | cytosol | cellular component | GO:0005829 | 3220 | 423 | 17570 | 1756 |
ACACB,TXN,ADD1,AK7,TSC22D3,DNAJC3,FBXO2,MMADHC,PSME1,IL18,NANS,CCNB1,CENPN,NCS1,CALM2,CDKN2C,TYMP,PSMD1,AP1M2,CTGF,ELMO2,ZFP36,CABP1,OSBPL3,RGS3,ALDH1A3,PALD1,STEAP2,PIK3CA,AOX1,TUBG1,IRF2,TACSTD2,PIK3CD,PACSIN1,TIAM1,APOBEC3G,METAP2,NWD1,CASP9,CDA,AGO4,PRKAR2B,SAV1,POR,ARF4,ABR,CARHSP1,PLCG1,MID1IP1,DNM1L,LIMK1,NOD2,HDAC1,DHTKD1,SERPINB6,ITPKA,HSPB1,TRAF5,F2RL1,GAB1,FGD1,DDX58,NFKBIE,SCOC,TBC1D1,CALB2,DGKQ,KIF23,ISYNA1,HERC6,PSIP1,LMNA,ATG4A,MECOM,PIK3AP1,RPL39,FAM13B,NEK2,PRKG1,PIKFYVE,NUP85,PPP6R1,MCCC2,GFPT1,HPS3,CALM1,AMER1,NPHP3,TP53INP2,PCTP,PSMA4,DCP2,PLIN5,RASA1,FAS,PRKAG2,PELI2,DCK,AGBL5,AURKA,MDH1,NDE1,ARPC2,MAP3K5,IFIH1,XDH,EGLN1,DOCK9,PLA2G4A,ARHGAP11A,MTM1,SLC2A4,CEP70,NQO1,PAPSS2,TRIP10,THRA,INPP5D,RPS6KA1,RALBP1,CAST,IQGAP1,PTTG1,NUF2,FTH1,BCL2L1,MVB12B,AIFM2,PRKACA,CCND1,SCNN1A,DACT1,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,PHKA2,RASGEF1A,CDKN2D,SULT2B1,ATG4D,GPX4,MX1,DOCK4,SEC23A,SEC61B,RIPK2,COG2,SAT1,CYS1,PANK1,PRKCQ,PKMYT1,RAB38,ITPR3,GABARAPL1,CEP162,IRS2,ALDH3B1,JAK1,CDK19,NGFRAP1,STK26,INPP4B,MLKL,MAPK12,TTC8,ARHGEF3,TNRC6C,CENPI,HABP4,HERC5,PKN1,NUCB2,SPR,GSTP1,CTNNBIP1,ADD3,PTEN,CALD1,SGK3,BAX,WWP1,MAPK11,CNOT6L,SPRY2,TRIM62,S100A6,PARP9,FARP2,AMOTL2,OPLAH,RASGRF1,ARAP2,ZWINT,ARHGEF28,SHMT1,PLSCR1,RAPGEF2,PIK3R1,EIF5A2,UBE2A,DIAPH2,BLVRA,YES1,FOS,KIF11,CPTP,DCTN6,RPL12,PGM2L1,ERAP1,GPER1,HMGA1,CENPE,FHL1,CMPK2,WDR45B,ESPL1,OCLN,ACOT7,MYL9,ILDR1,CASP3,EPAS1,CNOT8,CAMKK1,CUL4B,ARFGEF1,NDC80,NDRG2,VARS2,HDAC6,CACNB4,SLC8B1,TRIM68,SPTB,SH3KBP1,CHPF,RPS6KA2,SHC3,CNTRL,DPYSL2,CEP78,PAPSS1,DLG1,AKR1B1,TRPC1,MYH14,BTBD3,S100A13,NEB,RASGRP1,PLK1,NLRP4,CD55,KCNIP3,CENPA,TRIM8,ITCH,USP18,EZR,ARHGDIB,PRKRA,IDH1,SESN1,CDK1,RHEB,OPTN,DPYSL3,EDNRA,PLCH1,WIPI1,MADD,CAB39,SP6,PIK3C2B,RAP1GAP,MYL12B,CAPN1,RRAGD,PRKAA2,FAM213B,BMF,ARAP3,SERPINE2,PEX6,DNAJB2,RASA2,CALM3,RAB6A,NCKAP1,TEC,PHLPP1,CA2,GATA2,EXOC8,AHCY,PLCB2,CCDC88A,DPYSL5,TESK1,PCBP3,STRADB,PDE5A,IFIT3,NUBP1,RANBP9,AMDHD1,CDK5R1,RASGRP2,GNAS,MAPKAPK2,UAP1,PHLPP2,CDCA5,NFKBIA,NLRC5,RHOBTB2,CCNB2,JAK3,RNF146,CCNE2,LZTFL1,SORBS1,SPC25,UGP2,UPF3B,PSME2,TP53,STIL,BCAP31,ARHGEF16,WDR44,KIF14,PLCG2,FABP6,PLK4,DIXDC1,GOT1,NOTCH3,OAS3,TMEM64,EGLN3,F2R,DVL2,CTH,CHP1,MAP3K3,AKT1,OSTM1,CDC20,ACO1,GLO1,MYL12A,CASP4,ARHGAP35,SOCS3,JADE1,IDE,TLE1,IRF7,SPTBN5,ANXA9,LTA4H,GCLM,CMAS,FBLIM1,PINK1,PACSIN2,ENO2,ARHGEF11,RUSC2,CIT,HAL,BLVRB,GNE,CDCA8,PSMD10,CRABP2,AIP,VPS26A,CARD8,ADRBK1,TFAP2A,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,IQGAP3,SYK,MYO5A,FAH,PGM1,RHOA,RAB3B,PSMB4,GCLC,OGDHL,PRICKLE1,GGH,PELI3,FNDC3A,BORA,BBS2,BCAR1,MAPK8IP1,PRDX4,KLHL2,ARHGAP24,SWAP70,NAT1,RAP2C,DTX4,ARRB1,CEP41,UBE2C,AHR,ARHGEF9,ARHGEF4 |
| 1.112e-10 | -22.92 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | 325 | 71 | 17758 | 1761 |
CCNI,CASP3,TXN,NQO1,TRIP10,IL13RA1,FTH1,PLXNA1,BCAP31,CCND1,ZFYVE16,DPYSL2,IL6ST,VAT1,EGLN3,GM2A,SEPHS1,LAMP3,CYP1B1,LAMP2,DOCK4,FOXJ2,ACO1,SLC11A2,RAB38,LHFPL2,MAP3K6,ADRBK2,OPTN,DUOX1,JAK1,RBM47,RAB11FIP1,TRAF5,ST3GAL1,HSPB1,GCLM,CD63,SDC4,C6orf106,SLC1A3,C3orf18,SGPL1,TNS3,LYPD3,TMEM51,TPST1,CD9,TMBIM6,WBP5,FAM69A,GFPT1,LITAF,RUNX3,GGH,CYB5A,CD83,NCOA3,PVRL2,NAT1,SPINT2,NR4A3,NETO2,MDH1,LRRK1,ATP1B3,LTBP2,FZD5,NDE1,TBC1D4,ABCG1 |
| 1.156e-10 | -22.88 | regulation of protein kinase activity | biological process | GO:0045859 | 829 | 143 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,NRG2,PSME1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,SHC3,RGS3,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,PRKAR2B,CDK1,PLCG1,GPRC5B,MADD,NOD2,CAB39,HSPB1,GAB1,CDKN1C,RASA2,UBASH3B,CALM3,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,CALM1,STRADB,PDE5A,EPHA1,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,CSF1,STK39,MAP3K5,JAK3,CCNE2,SPRED1,AVPI1,NF2,IQGAP1,PSME2,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,APLP2,KIF14,CDKN1B,DAB2IP,RASGEF1A,F2R,CDKN2D,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,AKT1,RIPK2,FZD4,PKMYT1,DUSP4,CD40,MAP3K6,SOCS3,IRS2,PTPRJ,JAK1,STK26,STK38,CORO1C,SLC27A1,NRG1,SPTBN5,EFNA5,RGS14,NKX3-1,PINK1,SDC4,HERC5,PSMD10,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,PSMB4,RAPGEF2,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,RAP2C,ARRB1,GRIN2D,PPP2R3C,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 1.157e-10 | -22.88 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 697 | 123 | 17758 | 1761 |
AVPI1,EPAS1,FOXM1,CAST,TMEM41B,BCL2L1,CAMK1D,AIFM2,KBTBD11,SDC1,MNS1,CARD10,SYTL2,FANCI,IER3,CCND1,NOV,CTGF,IMPAD1,DPYSL2,MITF,TRPC1,RAB20,DAB2IP,SCARA3,TIPARP,MGAT5,MAP3K3,PCGF5,ING1,FBXL16,KCNIP3,CITED4,TNIP1,SLC39A8,HSPA12A,PLEKHO1,NUSAP1,LOXL2,PKMYT1,ATP1B1,SAV1,LHFPL2,ADRBK2,DPYSL3,IRS2,ANKRD10,ZNF114,BFSP1,JAK1,GPRC5B,C19orf66,P4HA2,ZNF367,TRIOBP,LEMD1,TANC2,MAFF,PRKAA2,IER5L,ANXA3,CTHRC1,LGALS3,HJURP,SERPINE2,ENO2,NUAK1,DCAF7,RASSF7,ARL4C,PDIA3,NTAN1,ETS1,C11orf95,TTYH3,SIRPA,SLC25A36,SNTA1,E2F7,ADD3,ITGA3,FJX1,UBE2J1,DAPK1,DRAM1,BUB1,PANX2,GPR161,REC8,FADS2,DDB2,PDGFC,PGM1,RAB3B,NR3C1,TESK1,RGMB,TACC1,GCLC,MPP1,ANO6,MYBL2,AK4,DIAPH2,ANTXR1,KIF11,C3orf58,FAS,CACHD1,SLCO4A1,SWAP70,UAP1,PLOD2,NFKBIA,CDCA5,STK39,CDK18,FHL1,NCAPG2,APOL2,NIPA1,MELK,EGLN1 |
| 1.328e-10 | -22.74 | YAMAZAKI_TCEB3_TARGETS_DN | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_DN | 205 | 52 | 17758 | 1761 |
WASF3,GCLM,SPRED1,CMAS,TTC39B,CDKN1C,LGALS3,GNPDA1,SLC25A13,CUL4B,COL18A1,SLC20A1,PSIP1,LBR,SIX4,TOP2A,EPCAM,IGF1R,CDH1,NEK2,AKR1B1,SORL1,CLDN4,CDH3,IGFBP2,ALDH7A1,PIM1,ZMYM1,S100A6,MCCC2,CKS2,SULF2,TGIF1,ALDH2,KIF20A,MYBL2,TFAP2C,TCF7,NUSAP1,YES1,KIF11,G2E3,KCNK1,CDCA7L,SPINT2,AURKA,HMGA1,FZD5,CBX7,COBL,JARID2,FGD1 |
| 1.383e-10 | -22.70 | whole membrane | cellular component | GO:0098805 | 1942 | 277 | 17570 | 1756 |
LAMP1,SUN1,ACACB,GAA,ATP8A1,RET,SYTL4,PJA2,SLC9A7,NCS1,PQLC2,AP1M2,CABP1,STEAP2,CLDN4,SNX16,TACSTD2,MARCH2,PACSIN1,LAMP2,SGCE,SPATA18,SNTB2,PRKAR2B,KIF13A,MCFD2,ARF4,ENPP1,DNM1L,ATP7B,NOD2,UNC5B,ARF6,LZTS1,DDX58,SCN5A,GGA1,HLA-E,TMEM55B,ITGA6,RAB23,SLC36A4,SLC1A3,FAM21C,MARCH8,ITGA3,SNX18,ZNRF2,VASN,FLRT3,PCYOX1,PIKFYVE,RIMS2,GPR161,EPB41L5,MMD,ATP8B3,ANTXR1,GNA11,STX3,CYB5A,FAS,GABRD,SCARB2,TJP3,SLC4A4,ITPR1,STK39,MAL2,PLIN3,RUSC1,TMEM173,EHD1,SPRED1,SLC2A4,TCTN2,ARMCX3,NLRX1,ST14,KCTD12,BCL2L1,MVB12B,SNN,AIFM2,PRKACA,APC2,REPS1,EPS8L2,ZFYVE9,ACAP2,SCNN1A,CDH1,CNNM4,ACSL4,PDE4D,TSPAN1,DLG3,RAB27B,SNX10,TMEM9,SEC23A,FZD4,CYS1,SYNE2,UTRN,SLC11A2,ATP1B1,RAB38,ITPR3,GABARAPL1,SHROOM3,STK26,SLC9A6,CORO1C,SIPA1L1,SLC27A1,NRG1,RGS14,TTC8,ATP9A,EPS8,SDC4,EFHD2,EFNB1,SRPX2,HLA-A,SNTA1,ANKS1B,PTEN,CD9,BAX,DRAM1,SLC44A2,ATP8B1,PLEKHF1,IGFBP2,ERBB3,SPRY2,TPCN1,AMOTL2,ACBD5,PLSCR1,RAPGEF2,GRIN1,FURIN,AIF1L,CPTP,GPLD1,RAB11FIP2,GRIN2D,ITGAV,GPER1,FZD5,WDR45B,OCLN,CYBRD1,CASP3,EPHA4,HDAC6,PDGFB,ABCD4,ZFYVE16,EPCAM,RAB15,SLC44A1,DLG1,ABCA2,TRPC1,RAB20,RP2,CTTN,MYRIP,LAMP3,CD55,EZR,RHEB,HPSE,WIPI1,KCNK1,RAB11FIP1,PRKCDBP,PIEZO1,NRGN,STARD3NL,RRAGD,BMF,PEX6,BVES,HLA-F,NCKAP1,CNTNAP2,DHRS3,ANO1,IGF1R,CA2,KCNN4,COL6A1,HLA-C,WNT3A,FAR2,GAD1,SLC12A2,KDELR1,ABCC1,RGMB,SPATA13,SCRIB,C3orf58,STEAP1,RASGRP2,EPN3,TMEM30A,PHLPP2,SH3BP4,CTSA,ATP1B3,PLD1,SHROOM2,PROM2,SORBS1,NF2,ERBB2,EMP2,ATP6V0B,WDR44,VAT1,RPN2,ECE1,LMAN1,F2R,CLCN3,EVA1A,OSTM1,ERBB2IP,DAG1,ATP13A2,DUOX1,PTPRJ,ATP1A1,PEX2,EFNA5,IRF7,SPTBN5,ABCA1,ARFGEF3,MAN2B2,ANXA3,SORT1,PACSIN2,GOLIM4,PINK1,CD63,LRP4,GABRG2,VPS26A,PARM1,FZD6,TMEM63A,M6PR,ADORA1,KIAA0319,ABCD1,DLGAP1,SUN2,RAB3B,RHOA,CRB3,IFITM3,PLAUR,LITAF,BBS2,HLA-B,RAP2C,ARRB1,NDFIP1,L1CAM,ARHGEF4 |
| 1.400e-10 | -22.69 | localization | biological process | GO:0051179 | 4664 | 588 | 16441 | 1675 |
ACACB,ADD1,SLC25A13,HEXB,RET,CACNA2D2,TGOLN2,SYTL4,CALM2,PQLC2,AP1M2,SEMA3G,PIK3CD,TINAGL1,TMEM37,TIAM1,PRKAR2B,LOXL2,ICMT,RNF19B,ARF4,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,ARF6,NXT2,SCN5A,NFKBIE,GGA1,ITGA6,SOX9,RAB23,SLC36A4,GPSM2,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,CADPS2,PANX2,NUP85,C9orf72,PPP6R1,SLC37A1,KIF20A,ERO1A,PCTP,SFXN5,PLIN5,CYB5A,PTPRF,CACHD1,SCARB2,SLC4A4,TIMM8A,SEMA4D,ITPR1,AURKA,NDE1,ARPC2,NUP58,XDH,MTM1,CCDC109B,INPP5D,C5orf30,PKP2,MVB12B,PRKACA,APC2,APPBP2,CCND1,SCNN1A,CDH1,ACSL4,ARL4D,DLG3,RAB27B,RASGEF1A,SNX10,TMEM9,SCN3A,SEC61B,FZD4,SYNE2,HTATIP2,NUSAP1,RAB38,SNX12,SHROOM3,CORO1C,SLC9A6,AXL,PRIMA1,RGS14,SLC25A30,TTC8,CTHRC1,TCAF1,SDC4,HABP4,BTN3A1,PDIA3,CTSZ,ANO9,PKN1,ETS1,GSTP1,SLC25A43,SRPX2,PDIA4,SGPL1,CXCL16,ADD3,SLC27A6,CTSC,BAX,KLC3,PLEKHF1,WWP1,TPCN1,S100A6,PARP9,ACBD5,LCA5,TACC1,RAPGEF2,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,NEURL1B,CNTNAP1,PITX2,RPL12,RAB11FIP2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,CENPE,USF2,WDR45B,CYBRD1,ILDR1,EPHA4,ARFGEF1,NDC80,F11R,ITPR2,HDAC6,PDGFB,NUP62CL,SDC1,SUSD2,NPNT,SLC44A1,MITF,ABCA2,TLN2,ANO4,SCARA3,TRAM1,S100A13,PLK1,KCNIP3,CELSR2,STAU2,EZR,ARFRP1,ANLN,CDK1,OPTN,TRIM9,KCNMB4,WIPI1,RAB11FIP1,PIEZO1,RRAGD,PRKAA2,LGALS3,FXYD3,SLC22A31,RAB6A,NCKAP1,CNTNAP2,ANO1,B4GALNT1,TNS3,RINL,GATA2,FRAS1,KIF13B,EXOC8,SELK,WNT3A,ABCC1,SPATA13,STRADB,SCRIB,EIF2AK1,CDK5R1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,SLC2A6,ZDHHC7,LTBP2,ATP1B3,PLD1,SEMA3A,NIPA1,UPF3B,TP53,SLC7A2,EMP2,STIL,BCAP31,SYTL2,TTC21B,PDGFA,ATP6V0B,PLCG2,LHX6,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,DVL2,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,PTK7,SYT13,ARFGEF3,BIN1,PINK1,MFSD14B,PACSIN2,GOLIM4,CD63,ADGRG1,CDCA8,GABRG2,SELL,PSMD10,CRABP2,AIP,VPS26A,SIRPA,SLC9A2,ZDHHC21,M6PR,CDK16,SGK1,ABCD1,SYK,ATP2B1,GCNT1,HES1,FBLN5,RHOA,CRB3,PPARA,PRICKLE1,COL7A1,BCAR1,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,SPCS3,NDFIP1,TBC1D4,ARHGEF9,LAMP1,SUN1,GAA,SLC35D2,HSPG2,TSC22D3,ATP8A1,TAP1,CCNB1,SLC20A1,NCS1,SLC9A7,CTGF,STIM1,ELMO2,OSBPL3,PIK3CA,SERINC2,KCNS3,STEAP2,SNX16,MARCH2,PACSIN1,XKR8,LAMP2,ORAI2,ACVR1C,SLC35C1,KIF13A,TNS1,MCFD2,SLC25A5,ZFAND5,SPNS3,SLC25A4,GNPTAB,SARAF,F2RL1,SEMA6B,MRC2,SLC25A27,NDUFA4,SLC1A3,S100A2,MESDC2,DOPEY2,ITGA3,CYR61,SNX18,SLC16A6,RPL39,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,SYTL3,RIMS2,TRAK2,EPB41L5,KCNJ12,PMPCB,MFI2,CALM1,ANO6,NPC2,ATP8B3,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,CSNK1G1,MATN2,FAM83D,SLC4A3,NR4A2,PLIN3,HOOK1,NRBP1,EHD1,MFSD3,PLA2G4A,SLC2A4,DLGAP5,ARMCX3,TRIP10,THRA,RALBP1,ATP2C2,FTH1,CD274,BCL2L1,DDR1,TMPRSS4,ZFYVE9,NOV,ACAP2,CNNM4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,SEMA3B,ATG4D,MYO5B,DOCK4,SEC23A,COG2,KIF1C,PRKCQ,SLC11A2,PYGO1,ATP1B1,ITPR3,ATP10D,NIN,DDOST,JAK1,SLC27A1,NRG1,DENND5B,ATP9A,EPS8,ARL4C,CYB561,DNAH3,EFNB1,FGF19,LGALS3BP,SIX4,SLC25A36,RNF128,PTEN,FUT8,CD9,SGK3,SLC44A2,ATP8B1,SPRY2,SLC16A5,NCOA2,ZWINT,ZC3H11A,FURIN,PARP4,YES1,CPTP,GPLD1,MAMDC4,FGFR2,ABCB1,GRIN2D,ARSB,SLC25A38,ESPL1,ESYT2,EXPH5,LTBP1,UGT8,CRYM,CPT2,MPP5,DNER,SLC8B1,ERP29,CACNB4,TMC1,SH3KBP1,ABCD4,ZFYVE16,RAB15,LRRC6,DPYSL2,DLG1,TRPC1,SUN3,RAB20,RP2,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,CENPA,STRIP2,ADRBK2,EDNRA,MDK,UEVLD,KCNK1,PCSK5,GRN,LASP1,ARAP3,BVES,PEX6,ETV5,ABCG2,CALM3,CA2,KCNN4,FXYD5,ZRANB1,SLC12A2,GAD1,CCDC88A,KDELR1,SNX7,MDFI,PODXL2,BTN3A2,NUBP1,STEAP1,MFSD7,GNAS,SLC6A6,PLPP3,TMEM30A,CDCA5,NFKBIA,SH3BP4,CTSA,PITPNA,SHROOM2,JAK3,APOL2,TOB1,SNX30,DYNLRB1,SLC25A24,SORBS1,ARHGEF16,SLC25A48,SVBP,ARTN,KIF14,ZDHHC12,FABP6,REEP1,RPN2,TWIST1,DIXDC1,F2R,SCYL3,CHP1,PTPRU,SLC39A8,OSTM1,ERBB2IP,ALDH5A1,PEX2,SPTBN5,ABCA1,ANXA3,SORT1,TSPAN15,FRMD6,LRP4,TGFBR1,HMGXB4,TMEM63A,KIF5B,MLPH,ADRBK1,ADORA1,LLGL2,BMP7,RRBP1,KIAA0319,MYO5A,SYPL1,SUN2,RAB3B,CFAP46,NR4A1,ASPM,ARHGAP24,ARRB1,MCUR1,GEM,PLOD3,CEP41,SOX8,L1CAM,RAB3IL1,ABCG1,SNPH |
| 1.404e-10 | -22.69 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16389 | 1683 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.491e-10 | -22.63 | GNF2_RRM2 | MSigDB lists | GNF2_RRM2 | 40 | 20 | 17758 | 1761 |
HMMR,PLK1,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,CDCA8,NUSAP1,KIF11,CDK1,TOP2A,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,MELK |
| 1.604e-10 | -22.55 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | 275 | 63 | 17758 | 1761 |
ANXA3,MTM1,CMAS,SLC25A24,LGALS3,MACC1,S100A11,GNE,SOX9,CDCA8,PBX3,EFHD2,ISYNA1,CAMK1D,CA8,EMP2,DENND2D,LGALS3BP,SH3KBP1,CXCL16,CDH1,NPNT,KCNN4,STEAP2,TNFRSF12A,MAPK11,TACSTD2,HYLS1,EGLN3,SLC12A2,MGAT5,SP5,CPD,THRB,ARAP2,CENPA,TIMP2,CITED4,PLSCR1,FZD4,USP18,PLAUR,PBK,CDC20,GALNT7,DUSP4,NFIB,SOCS3,PLCH1,MFAP3L,ENPP1,ATP1A1,PRPS2,CDCA5,DTX4,CLMN,KLF5,SERPINB6,MLKL,F2RL1,TMEM173,ABCG1,ARHGEF4 |
| 1.627e-10 | -22.54 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 200 | 51 | 17758 | 1761 |
KLK10,PAPSS2,CALB2,BLVRB,RET,SLC7A2,DHRS3,ELF3,IL17RB,CCND1,ADD3,SCNN1A,RPS6KA2,MLPH,IGF1R,IL6ST,REEP1,OPN3,FAM63A,FAM102A,MYBL1,SULT2B1,MAST4,TIPARP,TIAM1,RASGRP1,SEMA3B,CYP26B1,PPIF,HES1,CELSR2,PRSS23,SLC37A1,MICB,AMFR,SYBU,TFAP2C,ASB13,FOS,ENDOD1,TMEM164,ALDH3B1,PDLIM3,TJP3,DHRS2,WFS1,LRIG1,ANXA9,GLA,PTGES,TOB1 |
| 1.780e-10 | -22.45 | regulation of phosphorylation | biological process | GO:0042325 | 1425 | 218 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,NRG2,NDRG2,PSME1,IL18,NENF,CCNB1,PDGFB,BARD1,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,CTGF,NPNT,SHC3,IL6ST,RGS3,IL31RA,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,TNIP1,ITCH,PBK,EZR,PRKAR2B,PPP1R14C,CDK1,KDM4D,ENPP1,PLCG1,GPRC5B,ANKRD6,TRAF3IP1,MADD,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,PRKAA2,PIFO,CDKN1C,ITGA6,UBASH3B,RASA2,SOX9,CALM3,TEC,PHLPP1,FBLN1,MECOM,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,CALM1,PDE5A,STRADB,EIF2AK1,EPHA1,PSMA4,RANBP9,RASA1,CDK5R1,FAS,FECH,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,NLRC5,FAM83D,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,CCNE2,SPRED1,AVPI1,NF2,FOXM1,IL15,IQGAP1,PSME2,CTDSPL,TP53,ERBB2,PRKACA,EMP2,STIL,IER3,CCND1,PDGFA,APLP2,ST5,DACT1,KIF14,CDKN1B,DAB2IP,TWIST1,PDE4D,RASGEF1A,CDKN2D,F2R,CTDSP2,DVL2,FRS3,CHP1,CKS2,MAP3K3,SIRT1,PPIF,TIMP2,RIPK2,AKT1,FZD4,RAD17,PKMYT1,DUSP4,CD40,DAG1,MAP3K6,FZD7,SOCS3,IRS2,DNAJC10,PTPRJ,JAK1,PPP2R5A,STK26,RBL1,STK38,CORO1C,SLC27A1,EFNA5,NRG1,SPTBN5,RGS14,PINK1,NKX3-1,SDC4,LRP4,PSMD10,HERC5,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,SRPX2,FGF19,CD109,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,HES1,PDGFC,RASGRF1,RHOA,PSMB4,RAPGEF2,PLAUR,PIK3R1,GRIN1,PPARA,RGCC,YES1,MAPK8IP1,CDK5RAP1,BANK1,FGFR2,ACVRL1,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 1.789e-10 | -22.44 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 732 | 127 | 17758 | 1761 |
MFSD3,NF2,REPS2,CAST,CD82,CUL4B,LMCD1,F11R,BCL2L1,VASH1,OAT,PHLDA1,CMTM6,SUSD2,ELMO2,METTL7A,IMPAD1,DPYSL2,TSPAN6,RGS3,OSBPL3,PHTF1,AOX1,RP2,IFIT1,MTMR11,TINAGL1,TMEM64,SCARA3,SEMA3B,MYO5B,GCA,PCGF5,SSH3,TRIM8,TNIP1,FIGNL1,S100A4,CYB5R2,C3orf52,PTGER4,KIF1C,ARHGDIB,ROR1,KCTD2,MAP3K6,SNX12,ARF4,OPTN,PIAS3,TMEM164,WIPI1,GDE1,SLC9A6,AXL,VSIG10,SLC27A1,NXT2,DDX58,FBLIM1,NFKBIE,CPEB4,IGFBP6,ENO2,CHCHD7,FRMD6,DCAF7,RASSF7,PDCL,ABCG2,C6orf106,PSMD10,PBX3,TGFBR1,SAMD9,PM20D2,C3orf18,TTYH3,AIM1L,FAM111A,ITGA3,ITGB8,SPIN4,ALPP,LYPD3,KCNN4,MEGF8,FUT8,COL6A1,CD9,S100A6,NFE2L3,DPYSL5,GFPT1,PLEKHA6,PRSS23,RGMB,TACC1,MPP1,CORO2A,EIF5A2,MYEOV,IFIT3,BCAR1,NFIB,DCP2,STK17A,SLC6A6,TIMP3,COQ10A,H1F0,DHRS2,PHLPP2,AMMECR1,CDCA7L,SPINT2,MATN2,YOD1,STK39,TMEM159,IFIH1,JAK3,PTGES,COL16A1,TMEM173,EGLN1,EHD1 |
| 2.035e-10 | -22.32 | enzyme binding | molecular function | GO:0019899 | 1647 | 244 | 16491 | 1673 |
LAMP1,EXPH5,CASP3,EPAS1,DNAJC3,CUL4B,SYTL4,CCNB1,HDAC6,PJA2,CACNB4,BARD1,TRIM68,NCS1,FANCI,CDKN2C,CALM2,CYP1A1,UBE2T,ELMO2,STIM1,SHC3,DPYSL2,ZFP36,IL31RA,DLG1,CRY2,MYRIP,THRB,PLK1,LAMP2,TNIP1,CASP9,EZR,PRKAR2B,LDB2,PRKRA,SLC25A5,RNF19B,TYSND1,POR,RHEB,OPTN,PIAS3,CARHSP1,PLCG1,GPRC5B,DNM1L,HOXA9,RAB11FIP1,NOD2,PRKCDBP,CAB39,HDAC1,SERPINB6,ADIPOR1,ITPKA,ARF6,HSPB1,RAP1GAP,TRAF5,FGD1,PIFO,SCN5A,RUNX2,FXYD3,DGKQ,SOX9,CALM3,CNTNAP2,NCKAP1,ADAMTSL4,RABGGTA,TFAP4,ITGA3,KCNN4,BHLHE41,KIF13B,RANBP1,EXOC8,NEK2,SORL1,CD70,C9orf72,PPP6R1,SYTL3,RIMS2,CCDC88A,SOCS5,TRAK2,KIF20A,CALM1,STRADB,NPC2,EPHA1,RANBP9,RASA1,CYB5A,CDK5R1,PLIN5,FAS,MAPKAPK2,SCARB2,PRKAG2,NFKBIA,SH3BP4,FAM83D,FGD6,AURKA,CABIN1,YOD1,STK39,ATP1B3,MAP3K5,PER3,JAK3,TOB1,TMEM173,DOCK9,EGLN1,EHD1,CCNE2,TPRN,SPRED1,SORBS1,FOXM1,RALBP1,CAST,IQGAP1,TP53,PKP2,ERBB2,BCL2L1,PRKACA,EMP2,ARHGEF16,SYTL2,RAD23A,CCND1,ACAP2,SP100,DACT1,KIF14,CDKN1B,DAB2IP,PDE4D,NOTCH3,DLG3,CDKN2D,SNX10,NR2C1,CHP1,MYO5B,DOCK4,SIRT1,TIMP2,MBP,AKT1,FZD4,CDC20,UTRN,ATP1B1,CD40,SNX12,GABARAPL1,IRS2,DNAJC10,ATP1A1,PTPRJ,JAK1,PPP2R5A,CDK19,STK38,WFS1,CORO1C,TRIOBP,NRG1,MLKL,PRIMA1,ABCA1,BIN1,GCLM,NKX3-1,SORT1,PINK1,TSPAN15,RUSC2,EPS8,LRP4,SDC4,SELL,PKN1,TRIB2,ETS1,GSTP1,FZD6,SH2D4A,HDAC9,SNTA1,TOP2A,ADD3,MLPH,CTSC,LLGL2,PTEN,CST3,UBE2J1,TMBIM6,ABCD1,IQGAP3,CITED2,SPRY2,SYK,MYO5A,HES1,PLSCR1,PLAUR,AMFR,PIK3R1,GRIN1,UBE2A,FURIN,RGCC,PPARA,PARP4,DIAPH2,YES1,BCAR1,KIF11,BORA,MAPK8IP1,CDK5RAP1,TIMP3,SERPINA1,ACVRL1,RAB11FIP2,NR4A3,ARRB1,HMGA1,ITGAV,FZD5,UBE2C,PKIA,DIS3L |
| 2.091e-10 | -22.29 | organelle membrane | cellular component | GO:0031090 | 3010 | 398 | 17570 | 1756 |
SUN1,LAMP1,GAA,ACACB,SLC35D2,IL15RA,MRPS15,SLC25A13,ATP8A1,DNAJC3,RET,TAP1,FBXO2,SYTL4,PJA2,NCS1,SLC9A7,PQLC2,CYP1A1,AP1M2,STIM1,CABP1,CYP2S1,OSBPL3,STEAP2,FUT1,SNX16,MARCH2,PACSIN1,MGAT5,ERAP2,LAMP2,SPATA18,SNTB2,SLC35C1,PRKAR2B,KIF13A,GALNT7,MCFD2,ICMT,SLC25A5,POR,CYP4F3,ENPP1,SLC25A4,DNM1L,GNPTAB,ATP7B,SARAF,MRPS28,ARF6,MRPL44,SCOC,FAM169A,GGA1,HLA-E,TMEM55B,SLC25A27,RAB23,NDUFA4,SLC36A4,SLC1A3,COX6C,FAM21C,KIAA1161,LMNA,MARCH8,DOPEY2,ZNRF2,SNX18,VASN,FLRT3,ATP5H,BDH1,TPST1,PCYOX1,CADPS2,NCAM1,PIKFYVE,NDUFA12,NUP85,PPP6R1,GPR161,FAM69A,FADS2,B3GNT7,PMPCB,PRODH,MMD,LPGAT1,ERO1A,ATP8B3,SPTLC2,ANTXR1,SFXN5,GNA11,CYB5A,DGKH,SCARB2,TIMM8A,FAAH,ITPR1,MAP3K5,PLIN3,NUP58,TMEM173,EHD1,PLA2G4A,SLC2A4,CCDC109B,ARMCX3,CEP70,TCTN2,NLRX1,GALNT12,ATP2C2,BCL2L1,MGST2,MVB12B,SNN,AIFM2,APC2,CYP39A1,ZFYVE9,APPBP2,CDS1,ACAP2,SCNN1A,XYLT2,ACSL4,TSPAN1,RAB27B,SNX10,TMEM9,GPX4,MYO5B,MX1,SEC23A,SEC61B,COG2,FZD4,SYNE2,CYS1,SLC11A2,DNAJB14,PKMYT1,RAB38,ITPR3,TRIQK,ATP10D,COX20,GABARAPL1,DDOST,STK26,WFS1,SLC9A6,PNPLA6,TRABD2A,SLC27A1,HS3ST3B1,SLC27A3,SLC25A30,NR3C2,TTC8,ATP9A,CTSZ,SLC25A43,HLA-A,SGPL1,SLC25A36,AKIRIN1,FUT2,CTSC,MGAT4A,ALG13,FUT8,FAM20B,CST3,DRAM1,BAX,CD9,SLC44A2,PLEKHF1,TMBIM6,TPCN1,ACBD5,PDGFC,B3GNT2,MRS2,EIF5A2,ELOVL3,FURIN,C1GALT1C1,CPTP,GPLD1,GALNT3,NUCB1,PLOD2,RAB11FIP2,SYT7,ERAP1,GPER1,FZD5,SLC25A38,WDR45B,ESYT2,CPT2,EPHA4,ARFGEF1,MGAT5B,ITPR2,SLC8B1,PDGFB,SH3KBP1,CHPF,ABCD4,ZFYVE16,RAB15,RPS6KA2,SLC44A1,DLG1,ABCA2,RAB20,TECR,SCARA3,MYRIP,TRAM1,RASGRP1,SMAGP,LAMP3,CYP1B1,ATL1,NFE2L1,KLK6,MRPS36,PTGFRN,RHEB,OPTN,MAN2A2,HS6ST1,GPRC5B,HPSE,AGPAT2,WIPI1,DOLPP1,RAB11FIP1,PIEZO1,NRGN,RAP1GAP,STARD3NL,RRAGD,BMF,LMTK3,LGALS3,PEX6,FXYD3,HLA-F,ABCG2,RAB6A,B4GALT4,DHRS3,B4GALNT1,B3GALNT1,COL6A1,SUCO,SELK,HLA-C,FAR2,WNT3A,GAD1,ALDH3A2,MPHOSPH9,CKAP4,KDELR1,SNX7,CHSY3,CYP26B1,MRPS33,MGAT4B,GYLTL1B,EMC2,C3orf58,STEAP1,GLCE,GNAS,FECH,COQ10A,MFSD2A,TMEM30A,PHLPP2,PLPP3,ZDHHC7,CTSA,PLD1,TMEM120A,APOL2,PROM2,SLC25A24,XYLT1,PDIA5,ERBB2,FAM198B,LPIN3,PHLDA1,EMP2,BCAP31,CYP26A1,PDGFA,ATP6V0B,SLC25A48,CYP4F11,WDR44,REEP1,N4BP3,VAT1,RPN2,ECE1,NOTCH3,LMAN1,PDIA6,SEPHS1,CHP1,PPIF,SIRT1,CLCN3,EVA1A,OSTM1,COQ10B,SLC39A8,C3orf52,ERBB2IP,CASP4,ATP13A2,TAPBP,PEX2,SPTBN5,IRF7,CYP2U1,REEP4,AIFM3,ST3GAL1,NDST3,ARFGEF3,MAN2B2,ANXA3,PINK1,PACSIN2,GOLIM4,SORT1,CD63,POMGNT1,DSE,LBR,DNAJB9,PARM1,VPS26A,FZD6,TMEM63A,ZDHHC21,M6PR,A4GALT,RRBP1,KIAA0319,UBE2J1,SGK1,ABCD1,GCNT1,B3GALT6,SYPL1,SUN2,RHOA,RAB3B,IFITM3,NR4A1,AMFR,PLAUR,SYBU,LITAF,PRICKLE1,COL7A1,FNDC3A,BBS2,TXNDC11,MAPK8IP1,HLA-B,SERPINA1,RND3,RAP2C,PGRMC1,ARRB1,MCUR1,SPCS3,PLOD3,NDFIP1,TBC1D4,PTGES,ABCG1,GOLGB1 |
| 2.101e-10 | -22.28 | regulation of kinase activity | biological process | GO:0043549 | 874 | 148 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,NRG2,PSME1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,SHC3,RGS3,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,PRKAR2B,CDK1,PLCG1,GPRC5B,MADD,NOD2,CAB39,HSPB1,GAB1,PIFO,CDKN1C,RASA2,UBASH3B,CALM3,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,CALM1,STRADB,PDE5A,EPHA1,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,CSF1,NLRC5,STK39,MAP3K5,JAK3,CCNE2,SPRED1,AVPI1,NF2,IQGAP1,PSME2,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,APLP2,KIF14,CDKN1B,DAB2IP,RASGEF1A,F2R,CDKN2D,DVL2,FRS3,CHP1,CKS2,MAP3K3,SIRT1,AKT1,RIPK2,FZD4,PKMYT1,DUSP4,CD40,MAP3K6,SOCS3,IRS2,PTPRJ,PPP2R5A,JAK1,STK26,RBL1,STK38,CORO1C,SLC27A1,NRG1,SPTBN5,EFNA5,RGS14,NKX3-1,PINK1,SDC4,HERC5,PSMD10,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,PSMB4,RAPGEF2,PIK3R1,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,RAP2C,ARRB1,PPP2R3C,GRIN2D,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 2.140e-10 | -22.26 | BILD_E2F3_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_E2F3_ONCOGENIC_SIGNATURE | 226 | 55 | 17758 | 1761 |
CCNE2,HECA,UGT8,ENO2,FAM92A1,CDKN1C,LRP4,DGKQ,ABCG2,C5orf30,MRAS,PSIP1,PRRG4,ZNF275,SAC3D1,RAVER2,IL17RB,CDKN2C,RAB15,E2F7,SCNN1A,FAM46A,SLC16A6,LYPD6,REEP1,CEP78,ZDHHC23,AKR1B1,ATRNL1,EPB41L4B,TIAM1,TMEM200B,ZWINT,AKT1,AK4,RUNX3,CD83,NIN,MMP15,GNAS,ALDH5A1,CDK19,DCK,ZNF367,LRIG1,NETO2,SFMBT1,DONSON,TMOD2,EPB41L4A,CMPK2,SLC27A3,NIPA1,DIS3L,RRAGD |
| 2.183e-10 | -22.25 | LANDIS_ERBB2_BREAST_TUMORS_324_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 143 | 41 | 17758 | 1761 |
CMAS,DAP,FXYD3,CD82,FHDC1,CYB561,F11R,ITPR2,NUCB2,PDIA4,IER3,CCND1,EPCAM,WEE1,CTSC,NPNT,KCNN4,LMO4,FUT8,AIM1,PAPSS1,CD9,ACSL4,ERBB3,LMAN1,SLC12A2,TIAM1,SMAGP,WBP5,NR4A1,LITAF,TFAP2C,EZR,CDK1,MAPK8IP1,GALNT3,SHROOM3,DCK,PTK7,STK39,FGD1 |
| 2.435e-10 | -22.14 | regulation of developmental process | biological process | GO:0050793 | 2113 | 300 | 16441 | 1675 |
ACACB,SSH1,LGR4,TSC22D3,HEXB,RET,CACNA2D2,IL18,MORF4L2,PLXNA1,CAMK1D,CCNB1,VASH1,FAM101B,LTBP3,GRM5,NCS1,CTGF,PIK3CA,TACSTD2,SEMA3G,PACSIN1,TIAM1,ACVR1C,TFAP2C,LOXL2,SAV1,POR,ABR,ENPP1,PLCG1,DNM1L,PLK2,LIMK1,TRAF3IP1,NKD1,BMP1,HDAC1,ITPKA,ARF6,HSPB1,LZTS1,FGD1,SEMA6B,TBC1D1,NUAK1,SOX9,FAM21C,BMP2K,LMNA,MECOM,ITGA3,CYR61,MEGF8,BHLHE41,FLRT3,VASN,SORL1,TNFRSF12A,MYDGF,RIMS2,GPR161,SOCS5,EPB41L5,MMD,MFI2,ANO6,EPHA1,NPHP3,GNA11,NFIB,RASA1,FAS,PTPRF,AP1AR,NCOA3,SEMA4D,SETD3,CSNK1G1,FGD6,AURKA,SFMBT1,GDF11,ARPC2,MAP3K5,XDH,ADAMTS16,EGLN1,EHD1,FOXO6,GRHL2,THRA,INPP5D,RPS6KA1,PKP2,PRKACA,APC2,MNS1,TNFSF9,CCND1,NOV,SP100,DACT1,CDKN1B,DAB2IP,LGMN,ETV4,SEMA3B,SSH3,RIPK2,HTATIP2,FZD7,SHROOM3,CORO1C,AXL,SIPA1L1,INPP4B,TRIOBP,KLF5,NRG1,RGS14,COBL,MAPK12,WASF3,CTHRC1,NKX3-1,EPS8,PKN1,ETS1,SPR,SRPX2,TEAD3,ADGRB2,SIX4,NEO1,SGPL1,CTNNBIP1,PTEN,CST3,BAX,MAPK11,CITED2,SPRY2,TRIM62,TGIF1,RAPGEF2,PIK3R1,GRIN1,FOS,CDK5RAP1,FGFR2,NR1D2,ACVRL1,TBX18,ERAP1,ITGAV,GPER1,HMGA1,OSR1,ARSB,EMX1,EPHA4,HDAC6,PDGFB,SH3KBP1,NPNT,IL6ST,DPYSL2,ELF5,MITF,DLG1,DUSP10,NTN4,MYH14,CTTN,S100A13,RASGRP1,CYP1B1,STRIP2,ITCH,EZR,ARHGDIB,KLK6,CDK1,RHEB,DPYSL3,GPRC5B,HPSE,HOXA9,SP6,MAFF,MYL12B,GRN,ARAP3,RUNX2,LGALS3,SERPINE2,BVES,UBASH3B,ETV5,PHLPP1,FBLN1,CA2,GATA2,KIF13B,SUCO,C10orf54,WNT3A,ZRANB1,CCDC88A,HMG20B,PDE5A,CDK5R1,SOX13,GNAS,TMEM30A,CSF1,ITGA7,NFKBIA,FAM213A,JAK3,SEMA3A,RARG,TOB1,GAS2L1,HOXB7,NF2,IL15,FOXM1,TP53,ERBB2,IL27RA,OSR2,EMP2,PDGFA,KIF14,LMO4,BCL6,VAT1,CDH3,TWIST1,DIXDC1,TMEM64,NOTCH3,DVL2,SIRT1,TIMP2,AKT1,CDC20,CCSAP,CD40,DAG1,SOCS3,ARHGAP35,BHLHB9,PTK7,IRF7,EFNA5,ABCA1,BIN1,FBLIM1,ANXA3,SORT1,PINK1,ADGRG1,CIT,LRP4,GDF15,TGFBR1,CRABP2,TRIB2,FZD6,PPP2R3A,HDAC9,CD109,MYCL,BMP7,KIAA0319,TFAP2A,IQGAP3,SYK,TLE6,HES1,RHOA,ASPM,RGCC,MBNL3,PPARA,PRICKLE1,RUNX3,BBS2,CD83,HLA-B,FAT4,TWSG1,PPP2R3C,SOX8,NDFIP1,L1CAM,ABCG1 |
| 2.608e-10 | -22.07 | PH_domain | interpro domains | IPR001849 | 278 | 63 | 18293 | 1814 |
ARAP3,ARHGEF3,ARHGEF11,CIT,RASA2,TEX2,TEC,SBF1,PHLPP1,PHLDA1,ARHGEF40,SPTB,ARHGEF16,SNTA1,ACAP2,ADRBK1,RALGPS2,ELMO2,DOK4,OSBPL3,PLCG2,EXOC8,PLEKHF1,DAB2IP,RTKN2,CADPS2,TIAM1,FARP2,RASGRF1,ARHGEF28,ARAP2,PLEKHA6,AKT1,SNTB2,PLEKHO1,SPATA13,SNTB1,ANLN,ADRBK2,RASA1,ABR,ARHGEF26,ARHGAP24,DGKH,IRS2,PLCG1,PLCH1,PLEKHG6,SWAP70,ARHGEF19,PLEKHH2,TRIOBP,PLEKHG1,FGD6,SPTBN5,PLD1,AFAP1,GAB1,ARHGEF9,DEF6,DOCK9,ARHGEF4,FGD1 |
| 2.837e-10 | -21.98 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12854 | 1379 | 17775 | 1757 |
HECA,AK7,SLC25A13,RET,DPP8,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,PAQR5,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ABR,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,RANBP1,MAP3K9,CADPS2,ALPK1,ZMYM1,DGKG,MYLIP,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,GNA11,SFXN5,PLIN5,CACHD1,SLC4A4,ETS2,CLMN,GDF11,TMEM173,ADAMTS16,DOCK9,TPRN,NQO1,GRK6,MGST2,REPS1,APPBP2,RCN1,ST5,MUC16,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,MYT1,SNX10,MX1,COL6A2,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,ZNF618,GABARAPL1,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CKAP2,HABP4,SDC4,OSGIN2,BTN3A1,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,CXorf57,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,NENF,ITPR2,MGAT5B,SPTB,PLS3,BTG3,RPS6KA2,NPNT,IL6ST,PAPSS1,MITF,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,TRIM9,HS6ST1,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,ARRDC1,KLF11,RRAGD,PARP12,DNAJB2,FXYD3,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,PDK3,PRX,CDK5R1,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,CTDSPL,TMX4,TP53,STIL,SYTL2,TTC21B,PDGFA,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,ESPN,GLB1L2,NOTCH3,OAS3,LMAN1,SULF2,PPIF,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,ABHD12,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CPEB4,CDH22,KLHL13,HAL,CDCA8,HMGN3,AIP,LBR,VPS26A,FZD6,SH2D4A,NRP2,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,ALDH7A1,SYK,ATP2B1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,BBS2,TXNDC11,RNPEP,DGKE,SCG2,SH3BGRL2,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,FGD1,MRC2,CDKN1C,SCOC,TBC1D1,TNFRSF19,S100A2,TSPAN7,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,AIM1,TPST1,DAPK1,ADCK2,TMEM51,PRKG1,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,SFMBT1,CABIN1,CDK18,PLIN3,PER3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,DLGAP5,TCTN2,REPS2,ST14,RALBP1,CCDC110,ATP2C2,FTH1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,ACAP2,TRANK1,BRI3,PDE4D,EPHB4,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,TMEM144,KIF1C,ATP1B1,PKMYT1,PYGO1,ASB13,ITPR3,ALCAM,ATP10D,AMZ2,POPDC3,TRIOBP,ZNF704,FAM195A,PRR15,COBL,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,PBX3,HERC5,EFHD2,DNAH3,FGF19,HLA-A,WWP2,SCML1,SLC25A36,RASSF8,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,FARP2,PDGFC,ZWINT,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,ARSK,KIF11,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,METTL7A,ARHGEF37,ANKFN1,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,NLRP4,ITCH,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,HLA-C,C10orf54,ZRANB1,SLC12A2,ETV7,GAD1,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,LMO7,LZTFL1,NCKAP5,DYNLRB1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,SEPHS1,CKS2,PTPRU,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,RBMS2,MYO5A,PGM1,PHF20L1,RC3H2,SYBU,TTC7A,RUNX3,FOXL1,LEPR,ENDOD1,ARHGAP24,SWAP70,RND3,TRIM69,SPINT2,RAP2C,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,DNAJC3,MMADHC,CACNA2D2,NRG2,DHX8,LYNX1,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,SEMA3G,ACOX2,PIK3CD,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SH3BGRL,LOXL2,F12,ICMT,PPP1R14C,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,NFKBIE,FAM169A,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,NDE1,DRP2,ARPC2,EGLN1,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,PRSS22,IL13RA1,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,RTKN2,ARL4D,TMEM9,SCN3A,ENPP4,SSH3,CAMSAP3,PLEKHO1,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,PLEKHG1,INPP4B,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,HOXB2,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ANKS1B,ALG13,CALD1,ADAM15,ECI2,WWP1,MAPK11,NPTXR,SGCB,TPCN1,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,CENPE,USF2,CYBRD1,DCBLD1,UNKL,GNPDA1,CUL4B,EPHA4,FHDC1,NDC80,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,KLK6,ANLN,IDH1,ZBTB7B,LHFPL2,RHEB,DPYSL3,MFAP3L,PLCH1,WIPI1,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,HLA-F,ZCCHC24,UBASH3B,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,EPN3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,CCDC68,SLC7A2,FAM198B,LPIN3,KBTBD11,EFR3A,N4BP3,PLCG2,EGLN3,MINPP1,SCN2A,CTH,SIRT1,CPD,TMTC1,MBP,COQ10B,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,CMTM4,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,DAP,RUSC2,GNE,BLVRB,PSMD10,SELL,GABRG2,DSE,PPP2R3A,SLC9A2,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,IGDCC4,FAH,DLGAP1,HMMR,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,MAPK8IP1,PRDX4,CD83,FUCA1,BANK1,FAT4,SERPINA1,ZNF214,NAT1,CDCA7L,TMC5,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,NDFIP1,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,NCS1,SESN3,CTGF,ELMO2,PRICKLE3,IQCE,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,XKR8,LOC81691,ORAI2,KIFC2,SNTB2,PBK,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,RBM47,PLK2,GNPTAB,NKD1,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,SLC1A3,ISYNA1,KIAA1161,PRRG4,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,RUNDC3B,SORL1,CD70,PIKFYVE,RIMS2,IGSF3,FAM69A,EPB41L5,FADS2,B3GNT7,DDB2,PMPCB,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,CEP70,S100A11,TRIP10,NLRX1,RPS6KA1,CAST,IQGAP1,RNF182,CD274,TMPRSS4,MNS1,APLP2,ZNF75D,FAM46A,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,SP4,ZNF469,NIN,CMTM7,PRDM11,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,CCNJL,APOBEC3H,CYB561,SEPP1,SPR,LGALS3BP,SIX4,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,SPRY2,OSGIN1,NCOA2,RASGRF1,SHMT1,ARAP2,MPP1,PARP4,FURIN,LRRC1,GPLD1,MAMDC4,AMMECR1,CSTF2,PGM2L1,CCDC69,GRIN2D,ETAA1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,NMRK1,LTBP1,CPT2,HEBP1,CAMKK1,FLYWCH2,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,TSEN34,ABCD4,CHPF,NKAIN3,ARHGEF10L,C7orf49,LRRC6,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,POF1B,ANKRD12,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,STK17B,ADRBK2,EDNRA,CXXC4,LRRC42,MDK,NEIL1,ARHGEF19,ZNF114,UEVLD,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,AIM1L,OTUD1,ZNF432,CA2,NCEH1,ALS2CL,OXR1,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,ONECUT1,SLC6A6,UTP14C,NFKBIA,CDCA5,ALPK3,PITPNA,PROM2,KLF7,GAS2L1,FAM92A1,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,SUSD3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,LRP4,ARMC7,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,IRF2BPL,IL17RB,MDM1,MLPH,ADORA1,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,GCLC,DEPDC4,NR4A1,ASPM,LRRC66,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,HNRNPH2,PRCP,OTUB2,GEM,SOX8,L1CAM,SNPH |
| 2.926e-10 | -21.95 | LTE2_UP.V1_UP | MSigDB lists | LTE2_UP.V1_UP | 179 | 47 | 17758 | 1761 |
GCLM,EPAS1,GALNT12,ABCG2,NUCB2,PJA2,FAM46C,TNS3,ADORA1,DPYSL2,BMP7,MGAT4A,KIF13B,LMO4,ELF5,REEP1,OPN3,AOX1,DRAM1,SORL1,ECI2,ACOX2,SCARA3,SLC12A2,ULBP2,MYO5A,CYP1B1,GCNT1,SEC23A,PGM1,MBP,PBK,STAU2,PTGER4,DIAPH2,GGH,NPC2,DUSP4,SPTLC2,EPN3,SERPINA1,P4HA2,SLC9A6,FAM117A,CLMN,MAP3K5,RRAGD |
| 3.014e-10 | -21.92 | Golgi apparatus | cellular component | GO:0005794 | 1442 | 216 | 17570 | 1756 |
SLC35D2,HSPG2,IL15RA,ATP8A1,EPHA4,ARFGEF1,NDRG2,TGOLN2,MGAT5B,PJA2,PDGFB,SDC1,TRIM68,SLC9A7,NCS1,CHPF,AP1M2,MUC4,CTGF,GRHL1,CABP1,IMPAD1,PASK,STEAP2,KCNS3,FUT1,DLG1,DUSP10,RAB20,RP2,CTTN,SCARA3,PACSIN1,MGAT5,RASGRP1,ATL1,SPEF2,SGCE,KCNIP3,SLC35C1,ARFRP1,KIF13A,GALNT7,MCFD2,PTGFRN,ARF4,RHEB,OPTN,MAN2A2,HS6ST1,DNM1L,WIPI1,GNPTAB,ATP7B,BMP1,GLA,ARF6,RAP1GAP,NRGN,F2RL1,FGD1,PCSK5,PIFO,LMTK3,SCOC,NFKBIE,GGA1,HLA-E,HLA-F,RAB6A,CNTNAP2,B4GALT4,MECOM,B4GALNT1,DOPEY2,B3GALNT1,TPST1,PRKG1,SORL1,MDFIC,HLA-C,PIKFYVE,NCAM1,WNT3A,MPHOSPH9,PPP6R1,CCDC88A,KDELR1,CHSY3,B3GNT7,MMD,KIF20A,MGAT4B,GYLTL1B,ATP8B3,C3orf58,GLT8D2,GLCE,GNAS,AP1AR,H1F0,PLPP3,TMEM30A,FGD6,ZDHHC7,PLD1,ARPC2,PLIN3,TMEM173,RUSC1,PLA2G4A,SLC2A4,TRIP10,IL15,GALNT12,P3H2,CCDC110,XYLT1,ATP2C2,RGS20,FAM198B,PRKACA,EMP2,APC2,BCAP31,PDGFA,MUC16,CDH1,WDR44,ZDHHC12,XYLT2,ZDHHC23,PDE4D,NOTCH3,LMAN1,RAB27B,F2R,SCYL3,SULF2,CHP1,CPD,SEC23A,CLCN3,COG2,ACO1,KIF1C,SLC11A2,RAB38,PKMYT1,GABARAPL1,TAPBP,ATP1A1,STK26,SECTM1,KLF5,HS3ST3B1,ST3GAL1,NDST3,ABCA1,ARFGEF3,GLIS3,SORT1,GOLIM4,IGFBP6,ATP9A,SDC4,CTSZ,DSE,NUCB2,POMGNT1,PARM1,HLA-A,NEO1,ZDHHC21,GOLGA2P5,FUT2,RNF128,CTSC,A4GALT,MGAT4A,FAM20B,FUT8,TFAP2A,ATP8B1,MYO5A,GCNT1,B3GALT6,PDGFC,B3GNT2,PLSCR1,BCL9,SYBU,LITAF,FURIN,C1GALT1C1,DIAPH2,STMN3,MAML2,COL7A1,YES1,FNDC3A,CPTP,GALNT3,HLA-B,NUCB1,SERPINA1,RND3,FGFR2,DBI,ARRB1,GPER1,FZD5,ARSB,NDFIP1,ABCG1,GOLGB1 |
| 3.221e-10 | -21.86 | prostate | COSMIC cancer mutations | prostate | 14584 | 1533 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,CLMN,GDF11,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,ZNF365,ETV4,MYT1,SNX10,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,XRCC6BP1,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,FAM102A,IGFBP2,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PDK3,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,VPS26A,NRP2,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,ST14,CCDC110,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,PBX3,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,HDAC6,PDGFB,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,EZR,KLK6,ANLN,PRKRA,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,BLVRB,GABRG2,SELL,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,XKR8,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,CYB561,SEPP1,SPR,TEAD3,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,AMDHD1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,FAM92A1,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,PEX2,VSIG10,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.281e-10 | -21.84 | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | 241 | 57 | 17758 | 1761 |
TRIM2,UGT8,SPC25,ATP9A,CIT,ETV5,SDC4,NDC80,CDCA8,KIF23,EFHD2,IL13RA1,NUF2,CCNB1,TRIB2,CENPN,FZD6,IER3,CCND1,TOP2A,CTNNBIP1,E2F7,RNF128,UBE2T,SNX18,CYR61,PLK4,BUB1,ETV4,ALS2CL,TRIM62,CKS2,PLK1,MBP,FIGNL1,ASPM,CDC20,VWA1,NUSAP1,DUSP4,CCNF,ANLN,LHFPL2,MMP15,SLC6A6,RBL1,RND3,ZNF367,SH3BP4,TLE1,AURKA,SERPINB6,CCNB2,SEMA3A,CPPED1,ACOT7,MELK |
| 3.323e-10 | -21.82 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 466 | 90 | 17775 | 1757 |
NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,CDH1,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,PIK3R1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,GNAS,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 3.655e-10 | -21.73 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 474 | 91 | 17775 | 1757 |
NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,CDH1,PIK3CA,PLK4,EPHB4,CDKN2D,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,PIK3R1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,GNAS,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 3.690e-10 | -21.72 | GNF2_MKI67 | MSigDB lists | GNF2_MKI67 | 27 | 16 | 17758 | 1761 |
HMMR,CENPA,ZWINT,KIF20A,FOXM1,ASPM,CDC20,NUSAP1,KIF11,CDK1,TOP2A,AURKA,CENPE,UBE2C,ESPL1,MELK |
| 3.729e-10 | -21.71 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 347 | 73 | 17758 | 1761 |
SUN1,LMO7,ILDR1,NLRX1,ST14,FHDC1,SYTL2,ARHGEF16,CDS1,RPS6KA2,SCNN1A,GRHL1,MITF,DLG1,AOX1,SERINC2,CLDN4,TINAGL1,TSPAN1,SMAGP,FBXL16,SLC39A8,SNTB2,CASP9,EZR,KIF1C,MCFD2,ICMT,MID1IP1,RBM47,SIPA1L1,TRIOBP,LNP1,COBL,CAPN1,PRKAA2,PRSS8,LMTK3,LRRFIP2,MACC1,ELF3,IL17RB,FOXP2,DIRAS3,ITGB8,CTSC,RUNDC3B,OPN3,FAIM,C12orf75,SGCB,ALDH3A2,RBMS2,EPB41L5,SHMT1,PARP4,PRICKLE1,EPHA1,FNDC3A,AIF1L,BCAR1,BBS2,SPTLC2,NFIB,FRMD4B,MMP15,GALNT3,TJP3,FAAH,PITPNA,FHL1,AHR,OCLN |
| 3.860e-10 | -21.68 | neuron projection development | biological process | GO:0031175 | 866 | 146 | 16441 | 1675 |
MYL9,EMX1,UGT8,CUL4B,EPHA4,ARFGEF1,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,DLG1,TRPC1,NTN4,CTTN,MYH14,PACSIN1,TIAM1,BTBD3,RASGRP1,ATL1,CELSR2,EZR,ARF4,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,MYL12B,SCN5A,RASA2,CALM3,CNTNAP2,IGF1R,FRY,MEGF8,FLRT3,COL6A1,PRKG1,CACNA1D,NCAM1,WNT3A,DPYSL5,RGMB,CALM1,EPHA1,NFIB,PSMA4,RANBP9,STX3,CDK5R1,RASA1,PTPRF,SEMA4D,MATN2,CLMN,AURKA,PITPNA,NR4A2,ARPC2,JAK3,SEMA3A,KLF7,EHD1,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,PDGFA,ARTN,CDH1,FRYL,DACT1,DAB2IP,ACSL4,EPHB4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,SLC11A2,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,EPHA10,IRS2,JAK1,SLC9A6,SPTBN5,NRG1,EFNA5,LIFR,COBL,COL9A3,ARHGEF11,CIT,LRP4,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,NEO1,KIF5B,IGSF9,PTEN,CDK16,BMP7,SGK1,ERBB3,S100A6,FARP2,RASGRF1,RHOA,ARHGEF28,B3GNT2,PSMB4,FMN1,RAPGEF2,GRIN1,STMN3,YES1,CNTNAP1,FGFR2,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,RGMA |
| 3.912e-10 | -21.66 | stomach-carcinoma | COSMIC cancer mutations | stomach-carcinoma | 446 | 87 | 17775 | 1757 |
CAMKK1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,PIK3CA,PLK4,EPHB4,PIK3CD,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,PIK3C2B,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,PIKFYVE,SYK,TESK1,PIK3R1,PIP4K2C,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 4.179e-10 | -21.60 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 468 | 90 | 17775 | 1757 |
NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,CDH1,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,PIK3R1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,GNAS,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 4.230e-10 | -21.58 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1669 | 246 | 16441 | 1675 |
CASP3,TXN,PPP4R4,DNAJC3,CAMKK1,EPHA4,NRG2,NDRG2,PSME1,IL18,NENF,CCNB1,PDGFB,BARD1,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,CTGF,NPNT,SHC3,IL6ST,RGS3,IL31RA,PIK3CA,DLG1,DUSP10,CRY2,SLC39A10,RASGRP1,PLK1,TNIP1,ITCH,PBK,CDA,EZR,PRKAR2B,PPP1R14C,IDH1,CDK1,KDM4D,EDNRA,ENPP1,PLCG1,GPRC5B,DNM1L,ANKRD6,TRAF3IP1,MADD,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,PRKAA2,PIFO,LMTK3,PPP1R2,CDKN1C,NUAK1,ITGA6,UBASH3B,RASA2,SOX9,CALM3,TEC,PHLPP1,FBLN1,MECOM,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,PPP6R1,CCDC88A,GPR161,MDFI,SOCS5,MMD,CALM1,PDE5A,STRADB,EIF2AK1,EPHA1,NPHP3,PSMA4,RANBP9,RASA1,CDK5R1,FAS,GNAS,FECH,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,NLRC5,FAM83D,STK39,GDF11,MAP3K5,JAK3,XDH,EGLN1,PROM2,CCNE2,SPRED1,AVPI1,NF2,FOXM1,IL15,IQGAP1,PSME2,CTDSPL,TP53,ERBB2,PRKACA,EMP2,STIL,SYTL2,IER3,CCND1,PDGFA,APLP2,ST5,DACT1,KIF14,CDKN1B,DAB2IP,TWIST1,PDE4D,RASGEF1A,DLG3,CDKN2D,F2R,CTDSP2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,PPIF,CAMSAP3,TIMP2,RIPK2,AKT1,FZD4,CDCA2,RAD17,PKMYT1,DUSP4,CD40,DAG1,MAP3K6,FZD7,SOCS3,IRS2,DNAJC10,PTPRJ,JAK1,PPP2R5A,STK26,RBL1,WFS1,CORO1C,STK38,SLC27A1,EFNA5,SPTBN5,NRG1,RGS14,ABCA1,PPP2R2D,ARFGEF3,PINK1,NKX3-1,LRP4,SDC4,PSMD10,HERC5,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,SRPX2,FGF19,TIPRL,PPP2R3A,SH2D4A,CD109,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,HES1,PDGFC,RASGRF1,RHOA,PSMB4,RAPGEF2,PLAUR,PIK3R1,GRIN1,PPARA,RGCC,YES1,MAPK8IP1,GPLD1,CDK5RAP1,BANK1,SWAP70,FGFR2,ACVRL1,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 4.272e-10 | -21.57 | YANG_BCL3_TARGETS_UP | MSigDB lists | YANG_BCL3_TARGETS_UP | 348 | 73 | 17758 | 1761 |
MYL9,ARHGAP11A,CCNE2,DLGAP5,FOXM1,AASS,PTTG1,TAP1,CCNB1,SDC1,TNFSF9,ZNF385B,CDKN2C,RAB15,UBE2T,PLK4,TACSTD2,TMEM37,TLN2,MYBL1,RASGRP1,CD55,USP18,PBK,CDC20,NUSAP1,CDCA2,CDK1,ARHGEF26,RBM47,IRF7,SERPINI1,ABCA1,PCSK5,IGFBP6,DEPDC1,SCOC,CKAP2,PEX6,DNAJB2,CENPI,HERC6,MERTK,DTX3L,TOP2A,FAM111A,RALGPS2,CTSC,SGK3,LIMCH1,BUB1,DGKG,KIF20A,NR4A1,SYBU,MBNL3,VWA1,PDK3,IFIT3,TXNDC11,GLT8D2,FAM64A,NMI,MATN2,NR4A3,FAM83D,AURKA,CMPK2,UBE2C,CCNB2,SERPINB1,ESPL1,ACOT7 |
| 4.402e-10 | -21.54 | neuron development | biological process | GO:0048666 | 1007 | 164 | 16441 | 1675 |
MYL9,EMX1,UGT8,CUL4B,RET,EPHA4,ARFGEF1,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,TMC1,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,DLG1,TRPC1,NTN4,CTTN,MYH14,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,CELSR2,EZR,ARF4,DPYSL3,HS6ST1,PLCG1,MAP2,LIMK1,UNC5B,MYL12B,SCN5A,CDKN1C,RASA2,CALM3,CNTNAP2,SLC1A3,IGF1R,FRY,GATA2,MEGF8,FLRT3,COL6A1,PRKG1,CACNA1D,NCAM1,WNT3A,DGKG,DPYSL5,RGMB,CALM1,SCRIB,EPHA1,NFIB,PSMA4,RANBP9,STX3,CDK5R1,RASA1,PTPRF,SEMA4D,MATN2,CLMN,AURKA,PITPNA,NR4A2,ARPC2,JAK3,SEMA3A,KLF7,EHD1,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,PDGFA,ARTN,CDH1,DACT1,FRYL,LHX6,DAB2IP,ACSL4,EPHB4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,EPHA10,IRS2,JAK1,SLC9A6,SPTBN5,NRG1,EFNA5,LIFR,COBL,COL9A3,CTHRC1,ARHGEF11,CIT,LRP4,SDC4,PSMD10,PBX3,COL4A5,PLPPR4,SPR,FGF19,EFNB1,NRP2,NEO1,KIF5B,IGSF9,PTEN,CDK16,BMP7,ATP8B1,SGK1,ERBB3,S100A6,FARP2,RASGRF1,HES1,RHOA,ARHGEF28,B3GNT2,PSMB4,FMN1,RAPGEF2,GRIN1,STMN3,RUNX3,YES1,CNTNAP1,FAT4,FGFR2,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,RGMA |
| 4.771e-10 | -21.46 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7663 | 879 | 17775 | 1757 |
ACACB,ADD1,IL15RA,AASS,AK7,SLC25A13,DNAJC3,RET,CACNA2D2,MMADHC,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,CARD10,CMTM6,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,MUC4,KIAA1107,CABP1,PAQR5,ALDH1A3,SEMA3G,PIK3CD,TMEM37,TIAM1,MGAT5,APOBEC3G,ERAP2,SH3BGRL,PRKAR2B,LOXL2,F12,PPP1R14C,COL12A1,ABR,ENPP1,PLCG1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,FAM114A1,NOD2,AGFG2,HDAC1,SERPINB6,MRPS28,RELL1,GAB1,NXT2,NFKBIE,FAM169A,RAB23,SLC36A4,GPSM2,MERTK,LMNA,RAVER2,ELF3,MARCH8,GNS,TFAP4,FRY,PAIP2B,FAM189A1,MEGF8,RANBP1,MAP3K9,CADPS2,ALPK1,ZMYM1,NCAM1,MYLIP,NDUFA12,DGKG,NUP85,PPP6R1,C9orf72,MCCC2,HPS3,SLC37A1,PQLC3,SALL4,STAT4,MYBL2,NPHP3,SPTLC2,PCTP,SFXN5,GNA11,DCP2,CYB5A,STK17A,DHX32,PTPRF,CACHD1,SCARB2,NCOA3,ETS2,SEMA4D,SETD3,ITPR1,CLMN,DRP2,TMEM173,XDH,EGLN1,DOCK9,ARHGAP11A,MTM1,GRHL2,NQO1,PAPSS2,GALNT12,RGS20,TESK2,PKP2,IL13RA1,MGST2,PRKACA,APC2,ZNF385B,APPBP2,CDS1,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,SH3BP1,RTKN2,LRP11,TMEM9,SCN3A,ENPP4,MX1,COL6A2,RIPK2,PTPN9,SEPT6,PLEKHO1,SYNE2,SAT1,CDCA2,RAB38,ZNF618,GABARAPL1,IRS2,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,PRIMA1,ISOC1,TTC8,TNRC6C,CKAP2,HABP4,RASSF7,SDC4,BTN3A1,PDIA3,ANO9,NUCB2,ETS1,SLC25A43,SRPX2,BEX2,NEO1,PDIA4,CTNNBIP1,ADD3,ITGB8,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,MGAT4A,FAM20B,FAM102A,WWP1,IGFBP2,NPTXR,AMOTL2,ADAMTS2,LCA5,PLSCR1,FAM160A1,FMN1,RAPGEF2,PIK3R1,GRIN1,CXorf57,AK4,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,PLOD2,RAB11FIP2,NR1D2,SYT7,PPM1H,ITGAV,CMPK2,USF2,DCBLD1,CYBRD1,TLL2,KIAA1462,EPAS1,GNPDA1,EPHA4,CUL4B,ARFGEF1,LMCD1,TEX2,NENF,ITPR2,SDC1,SPTB,PLS3,NPNT,SHC3,IL6ST,PAPSS1,SLC44A1,ELF5,TMEM143,DUSP10,NTN4,ANO4,TLN2,MYBL1,TRAM1,DDX59,CCDC38,ZNF462,THRB,MCTP1,KCNIP3,CELSR2,EZR,ANLN,IDH1,SESN1,LHFPL2,RHEB,DZIP1L,DPYSL3,TRIM9,PLCH1,HS6ST1,KCNMB4,KLF12,WIPI1,MAP2,P4HA2,ZNF367,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,RRAGD,BMF,UBASH3B,ZCCHC24,ADCK5,RAB6A,CNTNAP2,NCKAP1,C3orf18,DHRS3,FBLN1,IL18R1,TNS3,DAZAP1,UBE2Q2,IGF1R,FRAS1,AHCY,MDFIC,PIM1,FAR2,WNT3A,ALDH3A2,MPHOSPH9,C9orf9,CYP26B1,CHSY3,DPYSL5,MRPS33,PCDH1,PLEKHA6,BTNL9,RGMB,CORO2A,ZNF320,TCF7,KBTBD2,PHLPP2,P4HA3,PRPS2,LTBP2,ZDBF2,PLD1,ATP1B3,SEMA3A,USP43,NF2,UGP2,CTDSPL,TMX4,XYLT1,TP53,CCDC68,ERBB2,LPIN3,KBTBD11,STIL,PDGFA,TTC21B,WDR44,EFR3A,LMO4,PLCG2,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,NOTCH3,MINPP1,EGLN3,LMAN1,SULF2,SIRT1,CLCN3,TMTC1,MBP,ERLEC1,AKT1,COQ10B,DAG1,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,ABHD12,PTK7,STK38,ADAMTS14,EFNA5,ANXA9,SYT13,ST3GAL1,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,BIN1,COL9A3,PINK1,PACSIN2,GOLIM4,CDH22,CPEB4,KLHL13,MACC1,RUSC2,DAP,BLVRB,GNE,GABRG2,HMGN3,DSE,VPS26A,PPP2R3A,SLC9A2,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,CCDC92,LYPD6,UBE2J1,GTF2F2,SGK1,ALDH7A1,ABCD1,ATP2B1,IGDCC4,NFE2L3,DLGAP1,RHOA,FBLN5,MOSPD2,IFITM3,NR3C1,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,GGH,FNDC3A,RNPEP,TXNDC11,MAPK8IP1,CD83,PRDX4,BANK1,FAT4,CDCA7L,NETO2,CLIP4,FAM117A,SH3BGRL2,NDFIP1,TBC1D4,HIPK3,ARHGEF4,GOLGB1,GAA,SLC35D2,TXN,PPP4R4,LGR4,HSPG2,SSH1,VANGL1,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,VASH1,OAT,SLC9A7,NCS1,SESN3,ANKS6,STIM1,OSBPL3,IQCE,PRICKLE3,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,SNX16,IRF2,IQCD,HYLS1,PACSIN1,RCAN3,METAP2,ORAI2,LOC81691,SPATA18,ACVR1C,SNTB2,CASP9,HSPA12A,KIF13A,TNS1,GALNT7,MCFD2,LDB2,CCNF,TP53I3,SPNS3,POR,ARHGEF26,PRIM1,AHRR,GDE1,GNPTAB,LRIG1,NKD1,BMP1,PRDM5,DHTKD1,SERPINI1,NFKBIZ,TANC2,UNC5B,TRAF5,LZTS1,FGD1,DDX58,MRC2,MRPL44,CDK17,FRMD4A,SCOC,TBC1D1,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,TNFRSF19,TSPAN7,PRRG4,DOPEY2,RALGPS2,ITGA3,PIK3AP1,ZNRF2,AIM1,BDH1,RUNDC3B,DAPK1,OPN3,ADCK2,TPST1,PRKG1,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,FAM69A,EPB41L5,DDB2,PMPCB,FADS2,TBC1D8B,MICB,LPGAT1,ANTXR1,NFIB,GLT8D2,RASA1,STX3,FAS,DGKH,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,PELI2,DCK,SLC4A3,FAM83D,FGD6,PCDH19,CABIN1,CDK18,PER3,MAP3K5,HOOK1,IFIH1,EHD1,FRMPD3,PLA2G4A,SPRED1,CEP70,IQGAP1,RPS6KA1,ATP2C2,MNS1,TMPRSS4,CYP39A1,ZFYVE9,APLP2,ACAP2,FAM46A,CNNM4,CDKN1B,PHKA2,NR2C1,MED30,ATG4D,MYO5B,COG2,PANK1,UTRN,TMEM144,PRKCQ,PYGO1,ATP1B1,C15orf39,ITPR3,ASB13,ALCAM,ATP10D,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,ZNF704,NRG1,KLF5,HS3ST3B1,NR3C2,COBL,DENND5B,WASF3,ATP9A,CENPI,EPS8,CCNJL,HERC5,PBX3,SPR,DNAH3,FGF19,TMCC3,SLC25A36,WWP2,RASSF8,RNF128,PTEN,FUT8,ATP8B1,CCDC82,OSGIN1,FARP2,RASGRF1,PDGFC,ARHGEF28,ARAP2,PARP4,FURIN,DIAPH2,C2orf69,YES1,LRRC1,GRTP1,KIF11,DCTN6,ACADSB,AMMECR1,ABCB1,ERAP1,CCDC69,PGM2L1,GRIN2D,ETAA1,WDR62,SLC25A38,ARSB,NCAPG2,MELK,OCLN,DEF6,JARID2,RGMA,ESYT2,EXPH5,LTBP1,UGT8,CRYM,MPP5,ERP29,DNER,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,NKAIN3,EPCAM,SIPA1L2,LRRC6,DPYSL2,IMPAD1,TSPAN6,ANKFN1,PHTF1,DLG1,POF1B,ANKRD12,TRPC1,AKR1B1,SUN3,RP2,MYH14,TECR,SLC39A10,PTPRE,MYRIP,RASGRP1,LAMP3,ATL1,TRIM8,ITCH,ROR1,PTGFRN,MRPS36,STK17B,ADRBK2,EDNRA,CXXC4,ARHGEF19,HPSE,KCNK1,MADD,GLA,CAPN1,CPPED1,STARD3NL,NR2C2,CD99,PPP1R2,LRRFIP2,PYROXD2,ETV5,ABCG2,CALM3,FAM81A,PHLPP1,ADAMTSL4,AIM1L,CA2,COL6A1,LIMCH1,C10orf54,ZRANB1,SLC12A2,ETV7,ALS2CL,ELK3,PODXL2,OXR1,VWA1,PDE5A,HEATR5A,STEAP1,RANBP9,MUM1L1,SOX13,GLCE,GNAS,BCAR3,XKRX,ONECUT1,UAP1,TMEM30A,SH3BP4,ALPK3,PITPNA,SHROOM2,COL16A1,SNX30,PROM2,KLF7,LMO7,GAS2L1,DYNLRB1,NCKAP5,FAM92A1,SPC25,IL15,HDAC11,PDIA5,MORC4,COL18A1,IL27RA,MRAS,LRRC45,SLC25A48,SS18,ZNF687,SETDB2,CYP4F11,KIF14,FRYL,REEP1,RPN2,DIXDC1,EPB41L4B,ECE1,F2R,SEPHS1,SUSD3,GCA,ZNF525,PTPRU,SLC39A8,OSTM1,CD40,DUSP4,DOCK5,CASP4,ALDH5A1,BFSP1,TLE1,OVOL1,SPTBN5,CYP2U1,ABCA1,LNP1,LIFR,GLIS3,ANXA3,SORT1,ARHGEF11,TSPAN15,POC1B,LRP4,ARMC7,MIER3,TGFBR1,COL4A5,TRMT2B,INTS8,TRIB2,HMGXB4,MDM1,ADORA1,TAF1B,ADRBK1,MLPH,LLGL2,BMP7,TOX2,GALNS,KIAA0319,CLIP2,MYO5A,RBMS2,SYPL1,RAB3B,GCLC,DEPDC4,ASPM,SYBU,OGDHL,MBNL3,LRRC66,TTC7A,KLHL2,SWAP70,RND3,SPINT2,OTUB2,ARRB1,GRAMD1C,ZMIZ1,SOX8,GEM,AHR,ABCG1 |
| 5.567e-10 | -21.31 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1682 | 247 | 16441 | 1675 |
CASP3,TXN,PPP4R4,DNAJC3,CAMKK1,EPHA4,NRG2,NDRG2,PSME1,IL18,NENF,CCNB1,PDGFB,BARD1,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,CTGF,NPNT,SHC3,IL6ST,RGS3,IL31RA,PIK3CA,DLG1,DUSP10,CRY2,SLC39A10,RASGRP1,PLK1,TNIP1,ITCH,PBK,CDA,EZR,PRKAR2B,PPP1R14C,IDH1,CDK1,KDM4D,EDNRA,ENPP1,PLCG1,GPRC5B,DNM1L,ANKRD6,TRAF3IP1,MADD,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,PRKAA2,PIFO,LMTK3,PPP1R2,CDKN1C,NUAK1,ITGA6,UBASH3B,RASA2,SOX9,CALM3,TEC,PHLPP1,FBLN1,MECOM,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,PPP6R1,CCDC88A,GPR161,MDFI,SOCS5,MMD,CALM1,PDE5A,STRADB,EIF2AK1,EPHA1,PDK3,NPHP3,PSMA4,RANBP9,RASA1,CDK5R1,FAS,FECH,GNAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,NLRC5,FAM83D,STK39,GDF11,MAP3K5,JAK3,XDH,EGLN1,PROM2,CCNE2,SPRED1,AVPI1,NF2,FOXM1,IL15,IQGAP1,PSME2,CTDSPL,TP53,ERBB2,PRKACA,EMP2,STIL,SYTL2,IER3,CCND1,PDGFA,APLP2,ST5,DACT1,KIF14,CDKN1B,DAB2IP,TWIST1,PDE4D,RASGEF1A,DLG3,CDKN2D,F2R,CTDSP2,DVL2,FRS3,CHP1,CKS2,MAP3K3,SIRT1,PPIF,CAMSAP3,TIMP2,RIPK2,AKT1,FZD4,CDCA2,RAD17,PKMYT1,DUSP4,CD40,DAG1,MAP3K6,FZD7,SOCS3,IRS2,DNAJC10,PTPRJ,JAK1,PPP2R5A,STK26,RBL1,CORO1C,WFS1,STK38,SLC27A1,EFNA5,SPTBN5,NRG1,RGS14,ABCA1,PPP2R2D,ARFGEF3,PINK1,NKX3-1,LRP4,SDC4,PSMD10,HERC5,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,SRPX2,FGF19,TIPRL,PPP2R3A,SH2D4A,CD109,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,HES1,PDGFC,RASGRF1,RHOA,PSMB4,RAPGEF2,PLAUR,PIK3R1,GRIN1,PPARA,RGCC,YES1,MAPK8IP1,GPLD1,CDK5RAP1,BANK1,SWAP70,FGFR2,ACVRL1,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 5.917e-10 | -21.25 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 88 | 30 | 17758 | 1761 |
HMMR,COL9A3,CENPA,ENO2,DLGAP5,HJURP,KIF20A,ASPM,PBK,CDC20,CDCA8,NUSAP1,GPSM2,CCNB1,KIF11,GLT8D2,CENPN,CDK1,NRP2,TOP2A,NEK2,CDH3,BUB1,CENPE,NCAM1,CCNB2,UBE2C,ESPL1,MELK,CKS2 |
| 6.000e-10 | -21.23 | KIM_WT1_TARGETS_DN | MSigDB lists | KIM_WT1_TARGETS_DN | 427 | 84 | 17758 | 1761 |
GAS2L1,PLA2G4A,DLGAP5,LGR4,XYLT1,NDC80,BCL2L1,BARD1,MNS1,APPBP2,CCND1,ACAP2,DPYSL2,KIF14,LMO4,ANKRD12,CDKN1B,IRF2,IFIT1,MANF,TECR,ARMCX6,MYBL1,CKS2,SIRT1,CENPA,SNTB2,DRAP1,CDC20,HTATIP2,TFAP2C,NUSAP1,CCNF,H2AFV,STK17B,CDK1,ATP10D,WIPI1,PLK2,HOXA9,NRG1,F2RL1,NUDT6,HJURP,CKAP2,NUAK1,CENPI,ARL4C,CDCA8,ASAH1,KIF23,NDUFA4,GPSM2,SAC3D1,TOP2A,FAM111A,MDM1,BHLHE41,NEK2,BUB1,ZMYM1,CITED2,PIKFYVE,MPHOSPH9,NCOA2,TGIF1,HES1,KIF20A,ASPM,RAPGEF2,KIF11,CDK5R1,KLHL2,GNAS,PITX2,FAM64A,PLOD2,AURKA,FGD6,HOXB13,CENPE,PER3,ESPL1,TOB1 |
| 6.108e-10 | -21.22 | LIU_CMYB_TARGETS_UP | MSigDB lists | LIU_CMYB_TARGETS_UP | 159 | 43 | 17758 | 1761 |
ZNF395,NQO1,SOX9,FAM134A,ARL4C,ISYNA1,TP53I11,PHLPP1,NUCB2,OAT,CA8,DNAJB9,SH2D4A,H1FX,SAC3D1,IL17RB,ADD3,RPS6KA2,WDR44,LHX6,DLG1,KCNS3,ALDH7A1,ECE1,CITED2,TSPAN1,TIPARP,MPHOSPH9,TGIF1,MMD,HSPA12A,SAT1,LITAF,AK4,PRKAR2B,PCTP,CRISPLD2,STK17A,RBM47,DHRS2,RAB11FIP1,TOB1,ACOT7 |
| 6.519e-10 | -21.15 | LEF1_UP.V1_DN | MSigDB lists | LEF1_UP.V1_DN | 183 | 47 | 17758 | 1761 |
DDX58,PRSS8,NUDT6,PAPSS2,ATP8A1,GALNT12,IL18,SAMD9,HERC6,SEPP1,ELF3,IL17RB,TNS3,AP1M2,CTGF,AIM1,OPN3,DAPK1,SORL1,MDFIC,DIXDC1,LIMCH1,MARCH2,OAS3,RAB27B,TSPAN1,MYRIP,ERAP2,CYP1B1,CYP26B1,PDGFC,USP18,SH3BGRL,STAT4,TMEM144,ATP1B1,ALCAM,DPYSL3,PIAS3,PITX2,ALDH5A1,RBM47,GDE1,PLOD2,RHOBTB2,HOXB13,TMEM14A |
| 7.606e-10 | -21.00 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 429 | 84 | 17758 | 1761 |
TXN,IL15RA,CAST,KCTD12,IL18,APOBEC3B,ACAP2,SETDB2,FAM46A,SP100,ELMO2,METTL7A,ZFP36,KLF3,BCL6,IFIT1,OAS3,LGMN,PDIA6,TIPARP,DDX59,APOBEC3G,SIRT1,MX1,MBP,SLC39A8,USP18,SAT1,PTGER4,RNF19B,SOCS3,RBM47,MADD,SECTM1,KLF5,REEP4,LTA4H,DDX58,SORT1,PINK1,FRMD4A,BLVRB,ARL4C,HERC5,SAMD9,HERC6,NTAN1,SEPP1,LGALS3BP,PDIA4,IRF2BPL,GNS,ADD3,ZNRF2,CTSC,SNX18,PIK3AP1,SLC16A6,FAM63A,SGK1,CCDC82,WWP1,CITED2,ATP2B1,ACBD5,ARAP2,B3GNT2,IFITM3,NR3C1,MPP1,SPATA13,PRICKLE1,BLVRA,IFIT3,SPTLC2,FAS,FUCA1,SCARB2,PRCP,NMI,CLIP4,CMPK2,IFIH1,USF2 |
| 7.751e-10 | -20.98 | HALMOS_CEBPA_TARGETS_DN | MSigDB lists | HALMOS_CEBPA_TARGETS_DN | 43 | 20 | 17758 | 1761 |
GAS2L1,HES1,TSC22D3,ARL4C,TFAP2C,ROR1,FZD7,ELF3,BCAR3,SCNN1A,CTGF,CYR61,RGS3,CLDN4,DUSP10,ERBB3,MTMR11,IFIT1,F2RL1,TOB1 |
| 8.948e-10 | -20.83 | Kinase-like_dom | interpro domains | IPR011009 | 524 | 97 | 18293 | 1814 |
CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,CAMK1D,GRK6,DDR1,PRKACA,DAPK2,WEE1,RPS6KA2,PASK,PIK3CA,PLK4,EPHB4,PIK3CD,SCYL3,MAP3K3,PLK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,CDK1,EPHA10,JAK1,STK26,CDK19,PLK2,PTK7,STK38,LIMK1,AXL,PIK3C2B,MLKL,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,TGFBR1,ADCK5,TEC,TRIB2,PKN1,MERTK,BMP2K,ADRBK1,IGF1R,CDK16,SGK3,NEK2,MAP3K9,PRKG1,ADCK2,DAPK1,SGK1,MAPK11,BUB1,ERBB3,ALPK1,PIM1,MAST4,SYK,TESK1,ADCK3,STRADB,EIF2AK1,YES1,EPHA1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,CSNK1G1,RYK,ALPK3,AURKA,STK39,CDK18,LRRK1,MAP3K5,JAK3,NRBP1,HIPK3,MELK |
| 9.284e-10 | -20.80 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | 197 | 49 | 17758 | 1761 |
CD99,CASP3,MTM1,TXN,DLGAP5,LGALS3,GNPDA1,CDCA8,EFHD2,BMP2K,TOP2A,CDKN2C,CA2,UBE2T,NEK2,PLK4,BUB1,MDFIC,TMEM37,SNX10,S100A6,CKS2,SYPL1,CENPA,PLSCR1,KIF20A,IFITM3,ASPM,S100A4,SH3BGRL,LITAF,NUSAP1,CCNF,ANLN,DOCK5,KIF11,CDK1,PRDX4,PRIM1,GALNT3,CARHSP1,H1F0,CDCA5,AURKA,SERPINB6,GEM,CCNB2,E2F8,ACOT7 |
| 9.485e-10 | -20.78 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | 191 | 48 | 17758 | 1761 |
SORT1,CCDC109B,PARP12,ADD1,IL15,TSPAN15,IQGAP1,TAP1,NOTUM,FAM198B,DDR1,FAM46C,SRPX2,BEX2,ANO1,NRP2,DAPK2,CDKN2C,PDGFA,RALGPS2,TMEM143,TPST1,BRI3,RFX5,FAIM,PTPRE,DDX59,EPB41L5,PPIF,PLEKHA6,FBLN5,SPATA13,EPHA1,CMTM7,HLF,H1F0,NR1D2,SLC4A3,ICOSLG,PLIN3,PER3,IFIH1,SERPINB1,GLCCI1,CAPN1,JARID2,MAPK12,ABCG1 |
| 9.683e-10 | -20.76 | WU_CELL_MIGRATION | MSigDB lists | WU_CELL_MIGRATION | 179 | 46 | 17758 | 1761 |
LGALS3,IGFBP6,EPAS1,ST14,FXYD3,ESRP1,SOX9,EPS8,ARL4C,RGS20,ASAH1,COL18A1,DSE,S100A2,FBLN1,SIRPA,EPCAM,SCNN1A,CDH1,RNF128,CYR61,AIM1,DAPK1,CLDN4,CDH3,TACSTD2,LIMCH1,TSPAN13,S100A6,ERAP2,PDGFC,CD55,COL6A2,S100A4,PTGER4,CDA,ARHGDIB,LOXL2,GALNT3,TIMP3,KCNK1,AXL,DTX4,KLF5,F2RL1,PTGES |
| 9.765e-10 | -20.75 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7606 | 871 | 17775 | 1757 |
ACACB,ADD1,IL15RA,AASS,AK7,SLC25A13,DNAJC3,HEXB,RET,CACNA2D2,DHX8,NRG2,IL18,SYTL4,LACTB2,CA8,BARD1,LTBP3,CALM2,CDKN2C,DAPK2,AP1M2,KIAA1107,CABP1,CYP2S1,PAQR5,ALDH1A3,KLF3,PIK3CD,TIAM1,MGAT5,ERAP2,NWD1,TNIP1,SH3BGRL,TMEM151A,PRKAR2B,LOXL2,F12,PPP1R14C,CYP4F3,COL12A1,ABR,ENPP1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,FAM114A1,NOD2,HDAC1,MRPS28,TMOD2,RELL1,ITPKA,HSPB1,GAB1,MTL5,SLC36A4,MERTK,TTYH3,LMNA,RAVER2,ATG4A,MARCH8,GNS,FRY,FAM189A1,RIMS3,MAP3K9,CADPS2,ALPK1,NCAM1,NDUFA12,DGKG,NUP85,C9orf72,MCCC2,HPS3,SLC37A1,PQLC3,SALL4,STAT4,MYBL2,ELK1,SPTLC2,SFXN5,GNA11,PSMA4,DCP2,STK17A,DHX32,PTPRF,CACHD1,SCARB2,SLC4A4,SEMA4D,SETD3,S100A5,CLMN,AURKA,GDF11,FBXO27,TMEM159,NDE1,DRP2,ARPC2,XDH,ADAMTS16,EGLN1,DOCK9,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,PTTG1,RGS20,PKP2,IL13RA1,ZNF385B,APPBP2,CDS1,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,XYLT2,RTKN2,RAB27B,SNX10,MYT1,TMEM9,SCN3A,MX1,SEC61B,COL6A2,RIPK2,PTPN9,SEPT6,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,XRCC6BP1,GABARAPL1,IRS2,PDLIM3,SHROOM3,CDK19,CORO1C,SIPA1L1,INPP4B,PLEKHG1,PRIMA1,MAPK12,TTC8,TNRC6C,HABP4,SDC4,PDIA3,ANO9,SLC25A43,NEO1,PDIA4,ADD3,ITGB8,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,FAM20B,KLC3,FAM102A,ADAM15,WWP1,IGFBP2,MAPK11,SGCB,CRTAP,ACBD5,AMOTL2,PVRL4,ADAMTS2,LCA5,PLSCR1,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,CXorf57,AK4,BLVRA,NEURL1B,SNTB1,CRISPLD2,PLOD2,RAB11FIP2,SYT7,PPM1H,USF2,DCBLD1,CYBRD1,ACOT7,TLL2,MYL9,KIAA1462,EPAS1,GNPDA1,FAM199X,PPM1J,CNOT8,EPHA4,ARFGEF1,LMCD1,TEX2,F11R,ITPR2,NUP62CL,SDC1,SPTB,PLS3,CPNE2,NPNT,SHC3,PAPSS1,SLC44A1,TMEM143,DUSP10,NTN4,ANO4,TLN2,TRAM1,NEB,SMAGP,CCDC38,ZNF462,PLK1,THRB,MCTP1,KCNIP3,CELSR2,EZR,CR2,KLK6,ANLN,IDH1,RHEB,DZIP1L,OPTN,TRIM9,PLEKHG6,MFAP3L,HS6ST1,KCNMB4,MSL1,AGPAT2,KLF12,WIPI1,MAP2,P4HA2,DOLPP1,ZNF367,KLF11,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MYL12B,RRAGD,RMND5A,UBASH3B,ADCK5,RAB6A,CNTNAP2,NCKAP1,FBLN1,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,MDFIC,FAR2,WNT3A,PLCB2,ALDH3A2,CYP26B1,CHSY3,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,TCF7,ANKRD29,G2E3,KBTBD2,PHLPP2,P4HA3,PRPS2,NLRC5,LTBP2,PLD1,ATP1B3,SEMA3A,CCNB2,USP43,NF2,UGP2,FOXM1,CTDSPL,TMX4,XYLT1,TP53,CCDC68,ERBB2,STIL,RAD23A,TTC21B,WDR44,EFR3A,LMO4,CDH3,GLB1L2,ESPN,OAS3,MINPP1,SCN2A,LMAN1,CTDSP2,DVL2,CTH,SULF2,CPD,SIRT1,CLCN3,TMTC1,MBP,ERLEC1,AKT1,COQ10B,PTGER4,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,ABHD12,RBL1,PTK7,ADAMTS14,EFNA5,ANXA9,SYT13,NDST3,CMTM4,BIN1,CMAS,GOLIM4,CDH22,CPEB4,RUSC2,DAP,HAL,ERI2,GABRG2,PSMD10,CRABP2,DSE,SLC9A2,PPP2R3A,NRP2,SIRPA,SH2D4A,CD109,C16orf74,LYPD6,GTF2F2,TSPAN13,BUB1,ALDH7A1,ABCD1,ATP2B1,FAH,NFE2L3,DLGAP1,FBLN5,MOSPD2,NR3C1,AMFR,MAML2,GGH,COL7A1,PELI3,FNDC3A,BBS2,MAPK8IP1,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,ICOSLG,NDFIP1,TBC1D4,PTGES,HIPK3,ARHGEF4,GOLGB1,LAMP1,GAA,SLC35D2,PPP4R4,LGR4,HSPG2,SSH1,VANGL1,TMEM41B,ATP8A1,PPFIBP2,PLXNA1,NANS,VASH1,SLC9A7,NCS1,SESN3,ANKS6,ZNF823,ELMO2,STIM1,ZFP36,OSBPL3,IQCE,IL31RA,AOX1,PIK3CA,ATRNL1,SNX16,IQCD,LOC81691,SGCE,KIFC2,SPATA18,ACVR1C,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,LDB2,SAV1,CCNF,ZFAND5,SLC25A5,ARHGEF26,AHRR,SLC25A4,PTER,GNPTAB,LRIG1,NKD1,PRDM5,SERPINI1,TANC2,UNC5B,F2RL1,FGD1,DDX58,MRC2,FRMD4A,TBC1D1,TMEM55B,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,S100A2,TNFRSF19,C9orf69,DOPEY2,RALGPS2,ITGA3,LYPD3,PIK3AP1,ZNRF2,BDH1,RUNDC3B,OPN3,ADCK2,TPST1,PRKG1,TMEM51,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,GPR161,FAM69A,EPB41L5,PMPCB,DDB2,KCNJ12,PRODH,KLK5,MFI2,TBC1D8B,LPGAT1,PIP4K2C,ANTXR1,NFIB,RASA1,STX3,MMP15,DGKH,AP1AR,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,PELI2,DCK,FAM83D,AGBL5,FGD6,SFMBT1,PCDH19,CABIN1,KLK7,NR4A2,MAP3K5,HOOK1,IFIH1,EHD1,FRMPD3,PLA2G4A,SPRED1,TCTN2,DLGAP5,CEP70,IQGAP1,RALBP1,RPS6KA1,THRA,ATP2C2,BCL2L1,TMEM170B,AIFM2,TMPRSS4,CYP39A1,ZFYVE9,EPS8L2,NOV,APLP2,ZNF75D,ACAP2,CNNM4,EPHB4,PHKA2,MED30,GPX4,ATG4D,MYO5B,SEC23A,CAPN6,UTRN,KIF1C,PRKCQ,PYGO1,ATP1B1,ITPR3,ALCAM,H2AFV,ATP10D,SP4,ZNF469,CMTM7,PRDM11,NIN,PPP2R5A,JAK1,DDOST,TSPAN18,ZNF704,SLC27A1,NRG1,MLKL,HS3ST3B1,NR3C2,COBL,CBX7,DENND5B,WASF3,PCOLCE,ATP9A,CENPI,EPS8,CCNJL,HERC5,PBX3,FBXO6,SPR,DNAH3,SIX4,TMCC3,SLC25A36,WWP2,RASSF8,E2F7,FAM111A,TMEM87B,RNF128,PTEN,FUT8,CD9,ATP8B1,SLC44A2,NCOA2,FARP2,TGIF1,PDGFC,ARHGEF28,SHMT1,ARAP2,ERMAP,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,DIAPH2,FBXO9,YES1,LRRC1,GRTP1,KIF11,DCTN6,NUCB1,ACADSB,FGFR2,TBX18,AMMECR1,ABCB1,ERAP1,PGM2L1,GRIN2D,ARSB,CXorf56,MELK,OCLN,DEF6,JARID2,RGMA,ESYT2,EXPH5,LTBP1,UGT8,CRYM,HEBP1,MPP5,DNER,CACNB4,TMC1,SH3KBP1,PTCHD4,ABCD4,ARHGEF10L,NKAIN3,ZFYVE16,SIPA1L2,LRRC6,ARHGEF37,SIVA1,DPYSL2,IMPAD1,ANKFN1,PHTF1,DLG1,POF1B,TRPC1,AKR1B1,SUN3,RAB20,RP2,TECR,SLC39A10,PTPRE,MYRIP,RASGRP1,LAMP3,ATL1,TRIM8,ITCH,ROR1,PTGFRN,ADRBK2,EDNRA,CXXC4,MAN2A2,ARHGEF19,HPSE,KCNK1,MADD,ADIPOR1,NRGN,CAPN1,CPPED1,PCSK5,NR2C2,LASP1,ZNF395,LRRFIP2,BVES,ETV5,ABCG2,CALM3,SAMD9,FAM81A,PHLPP1,ADAMTSL4,AIM1L,COL6A1,FXYD5,LIMCH1,ZRANB1,LRIF1,SLC12A2,ETV7,ALS2CL,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,AMDHD1,RANBP9,MUM1L1,SOX13,GNAS,BCAR3,XKRX,FECH,SLC6A6,UAP1,UTP14C,TMEM30A,SH3BP4,PITPNA,SHROOM2,COL16A1,APOL2,SNX30,KLF7,CCNE2,LMO7,LZTFL1,NCKAP5,DYNLRB1,FAM92A1,SPC25,PDIA5,COL18A1,IL27RA,KCTD9,LRRC45,SLC25A48,SS18,CYP4F11,ZDHHC12,FRYL,REEP1,RPN2,DIXDC1,EPB41L4B,ECE1,F2R,SEPHS1,PTPRU,SLC39A8,GLO1,DOCK5,CASP4,ALDH5A1,BFSP1,TLE1,OVOL1,VSIG10,SPTBN5,ABCA1,LNP1,LIFR,GLIS3,ANXA3,GCLM,ARHGEF11,TSPAN15,POC1B,FRMD6,LRP4,ARMC7,TGFBR1,TRMT2B,INTS8,TRIB2,TMEM63A,IL17RB,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,GALNS,KIAA0319,IQGAP3,MYO5A,RBMS2,B3GALT6,PGM1,SYPL1,RAB3B,NR4A1,DEPDC4,ASPM,RC3H2,OGDHL,MBNL3,LRRC66,TTC7A,RUNX3,KLHL2,ENDOD1,SWAP70,TRIM69,PRCP,SPINT2,ARRB1,GRAMD1C,HOXB13,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1 |
| 9.767e-10 | -20.75 | regulation of locomotion | biological process | GO:0040012 | 725 | 126 | 16441 | 1675 |
NF2,ATP8A1,RET,COL18A1,PKP2,PLXNA1,CD274,CAMK1D,VASH1,HDAC6,PDGFB,EMP2,GRM5,HTR1D,PDGFA,EPCAM,DAPK2,NOV,SVBP,ARTN,SP100,KIF14,DAB2IP,TWIST1,TACSTD2,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,CYP1B1,SEMA3B,DOCK4,TRIM8,AKT1,ACVR1C,PTPRU,SYNE2,CCSAP,PTGER4,ARHGDIB,DOCK5,DAG1,ABR,DPYSL3,IRS2,PLCG1,PTPRJ,CORO1C,NKD1,FAM110C,NOD2,NRG1,HSPB1,F2RL1,GAB1,DDX58,SEMA6B,ANXA3,TCAF1,ARAP3,SERPINE2,LGALS3,ADGRG1,BVES,SOX9,SDC4,SELL,PKN1,ETS1,FBLN1,SRPX2,LMNA,NRP2,PPP2R3A,HDAC9,CXCL16,ITGA3,ADORA1,IGF1R,CYR61,PTEN,MEGF8,SGK3,SGK1,ADAM15,TRIM21,SORL1,CITED2,WNT3A,TRIM62,EPB41L5,SUN2,RHOA,IFITM3,MPP1,RAPGEF2,PIK3R1,ANO6,FURIN,RGCC,SPATA13,EPHA1,BCAR1,BBS2,STX3,GPLD1,ONECUT1,AP1AR,SWAP70,PVRL2,SEMA4D,SCG2,ACVRL1,PLPP3,PRCP,CSF1,SPINT2,RAP2C,EGFL7,ITGAV,GPER1,PLD1,CFAP20,ARSB,SEMA3A |
| 9.890e-10 | -20.73 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 467 | 89 | 17758 | 1761 |
SPRED1,IQGAP1,GALNT12,CUL4B,LMCD1,FAM198B,BCL2L1,PHLDA1,CALM2,WEE1,IL6ST,KLF3,BCL6,IFIT1,ACOX2,CTTN,LMAN1,GM2A,DOCK4,CD55,CYB5R2,SAT1,EZR,ROR1,DNAJB14,SAV1,CMTM7,DPYSL3,ANKRD10,JAK1,UEVLD,MAP2,NFKBIZ,F2RL1,NXT2,CDK17,CPEB4,CDKN1C,SERPINE2,ITGA6,UBASH3B,ARL4C,MIER3,C6orf106,EFHD2,CALM3,TGFBR1,POMGNT1,HDAC9,AKIRIN1,E2F7,ITGB8,OPN3,NCEH1,ATP2B1,CCDC88A,RASGRF1,PDGFC,ELK3,ZC3H11A,CALM1,IFIT3,LEPR,DCP2,MAPK8IP1,FAS,AP1AR,SCARB2,SLC6A6,TIMP3,PLEKHH2,ETS2,KBTBD2,TMEM30A,NFKBIA,OTUB2,PGM2L1,NR4A2,PLD1,HMGA1,LTBP2,GEM,TBC1D4,CPEB2,TOB1,TMEM173,PKIA,DCBLD1,ESYT2 |
| 9.977e-10 | -20.73 | GTGCCTT,MIR-506 | MSigDB lists | GTGCCTT,MIR-506 | 690 | 119 | 17758 | 1761 |
SPRED1,UPF3B,PAPSS2,RPS6KA1,IQGAP1,RALBP1,CTDSPL,SH3KBP1,ZNF687,ARHGEF37,WDR44,DACT1,LMO4,MITF,SERINC2,BCL6,VAT1,RASGEF1A,MYRIP,CTDSP2,CPD,PPIF,CAPN6,FZD4,SERTAD4,PTPN9,HTATIP2,RAB38,RAD17,DNAJB14,TYSND1,NFIX,MDK,PGF,ATP1A1,MID1IP1,RBL1,P4HA2,STK38,LRIG1,RAB11FIP1,OVOL1,ARRDC1,SLC27A1,NR3C2,LZTS1,ABCA1,CMTM4,CAPN1,NR2C2,LRRFIP2,TBC1D1,ZCCHC24,SDC4,EPS8,AES,NKRF,TGFBR1,FAM81A,ARHGEF40,EFNB1,SIX4,SLC9A2,NRP2,SGPL1,HDAC9,IRF2BPL,SNTA1,TFAP4,ITGA3,RNF128,ANKS1B,MGAT4A,FLRT3,FRAS1,PCYOX1,DAPK1,SLC44A2,SGK1,ABCD1,LIMCH1,PIM1,SLC12A2,C9orf72,SOCS5,SYPL1,PGM1,ELK3,NR3C1,NR4A1,FURIN,PIP4K2C,PDE5A,FAM133B,C2orf69,LRRC1,AIF1L,SPTLC2,TP53INP2,PDIK1L,C3orf58,CYB5A,GLCE,MAPKAPK2,TWSG1,ITGA7,AMMECR1,NR4A3,PCDH19,FAM117A,PITPNA,STK39,SOX8,FBXO27,PLOD3,RARG,AHR,NIPA1,ESYT2 |
| 1.019e-09 | -20.70 | tissue development | biological process | GO:0009888 | 1601 | 236 | 16441 | 1675 |
EXPH5,EMX1,CASP3,GAA,HSPG2,LGR4,RET,EPHA4,MPP5,F11R,PLXNA1,CCNB1,FAM101B,CACNB4,PDGFB,DNER,SDC1,TMC1,PLS3,EPCAM,CYP1A1,CTGF,GRHL1,STIM1,NPNT,IMPAD1,ALDH1A3,MITF,ELF5,DLG1,PIK3CA,TACSTD2,MYH14,SEMA3G,ZBTB18,TIPARP,CYP1B1,THRB,EZR,TFAP2C,KLK6,LOXL2,LDB2,SAV1,ZFAND5,ZBTB7B,CDK1,COL12A1,ARHGEF26,EDNRA,ENPP1,HLF,AGPAT2,PTER,TRAF3IP1,BMP1,HDAC1,F2RL1,GAB1,E2F8,MAFF,HOXC13,SEMA6B,RUNX2,LGALS3,SERPINE2,BVES,ITGA6,SOX9,RAB23,TEC,NCKAP1,GPSM2,MERTK,TNFRSF19,KIAA1161,LMNA,ELF3,MESDC2,MECOM,ITGA3,CA2,IGF1R,CYR61,GATA2,MEGF8,FRAS1,FLRT3,COL6A1,WNT3A,SLC12A2,ALDH3A2,EPB41L5,KLK5,SALL4,AMER1,ANO6,HMG20B,SCRIB,NPHP3,C3orf58,NFIB,GNAS,MMP15,ONECUT1,NCOA3,ETS2,SEMA4D,ITGA7,CSF1,FAM83D,KLK7,GDF11,SEMA3A,RARG,EGLN1,ADAMTS16,NF2,GRHL2,ST14,THRA,IQGAP1,TP53,PKP2,COL18A1,ERBB2,OSR2,PRKACA,DDR1,STIL,PDGFA,CCND1,NOV,ARTN,SETDB2,LMO4,CDH3,CNNM4,TWIST1,PDE4D,DLG3,MINPP1,ETV4,DVL2,SULF2,SEMA3B,AKT1,FZD4,S100A4,IGSF8,PRKCQ,DUSP4,DAG1,FZD7,ARHGAP35,SOCS3,BFSP1,SHROOM3,PTK7,CORO1C,SECTM1,OVOL1,NRG1,KLF5,LTA4H,COBL,CTHRC1,TNRC6C,NKX3-1,FRMD6,LRP4,SDC4,TGFBR1,CTSZ,CRABP2,FGF19,EFNB1,HOXB2,FZD6,PPP2R3A,NRP2,SIX4,ZDHHC21,CD109,CTNNBIP1,E2F7,MDM1,ITGB8,PTEN,BMP7,FJX1,CST3,BAX,TFAP2A,ADAM15,ERBB3,TAGLN2,CITED2,SGCB,SPRY2,MYO5A,GCNT1,TGIF1,HES1,RHOA,FMN1,BCL9,RAPGEF2,PPARA,PRICKLE1,COL7A1,RUNX3,FNDC3A,FOS,BBS2,FOXL1,GPLD1,ARHGAP24,PITX2,TIMP3,FAT4,ACVRL1,FGFR2,TWSG1,CTSV,DBI,RAP2C,SPINT2,TBX18,NR4A3,HOXB13,ITGAV,PLOD3,FZD5,OSR1,SOX8 |
| 1.023e-09 | -20.70 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 440 | 85 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 1.023e-09 | -20.70 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 440 | 85 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 1.049e-09 | -20.68 | KANG_DOXORUBICIN_RESISTANCE_UP | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_UP | 52 | 22 | 17758 | 1761 |
HMMR,PLK1,CENPA,ZWINT,HJURP,NQO1,FOXM1,ASPM,PBK,CDC20,CDCA8,NUSAP1,BARD1,CDK1,FANCI,TOP2A,FOSB,PLK4,AURKA,BUB1,NCAPG2,ABCC1 |
| 1.049e-09 | -20.68 | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | MSigDB lists | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | 52 | 22 | 17758 | 1761 |
HJURP,SPC25,KIF20A,CDCA8,MORC4,CDCA2,KIF11,MNS1,CENPN,MESDC2,ENDOD1,CDKN2C,E2F7,PDLIM3,ZNF367,CDCA7L,FAM83D,AURKA,DONSON,MYBL1,MED30,MELK |
| 1.096e-09 | -20.63 | SMID_BREAST_CANCER_BASAL_DN | MSigDB lists | SMID_BREAST_CANCER_BASAL_DN | 653 | 114 | 17758 | 1761 |
SIGIRR,ACACB,BCAM,REPS2,NQO1,HEBP1,ATP8A1,HDAC11,RET,CACNA2D2,C5orf30,ERBB2,FAM198B,TRIM68,CYP26A1,SYTL2,APPBP2,CDS1,CCND1,SCNN1A,LRRC6,IL6ST,REEP1,FOSB,AOX1,TMEM143,ATRNL1,CRY2,SEMA3G,ACOX2,RAB27B,TSPAN1,DLG3,MYT1,SEMA3B,CPD,SSH3,SH3BGRL,STAU2,C3orf52,GALNT7,RAB38,DUSP4,ALCAM,ARHGAP35,CXXC4,ENPP1,MSL1,RBM47,ATP7B,MMP17,LRIG1,RAB11FIP1,INPP4B,SERPINI1,ANXA9,TRAF5,HSPB1,PCSK5,ZCCHC24,BLVRB,MTL5,ASAH1,CYB561,GDF15,COL4A5,ISYNA1,CNTNAP2,NUCB2,SEPP1,FBLN1,HOXB2,ANO1,MDM1,MLPH,IGF1R,FRY,RALGPS2,GATA2,SLC16A6,FLRT3,KIF13B,CST3,FUT8,SORL1,WWP1,TSPAN13,CACNA1D,ERBB3,MAST4,MCCC2,FAH,PRSS23,SYBU,BLVRA,SPTLC2,MFSD7,CYB5A,NCOA3,TJP3,ACADSB,FAAH,DHRS2,NAT1,ITGA7,TMC5,ITPR1,TCEAL4,NR4A2,STK39,TOB1,CYBRD1,SNPH,ABCG1 |
| 1.114e-09 | -20.62 | neurotrophin TRK receptor signaling pathway | biological process | GO:0048011 | 394 | 80 | 16441 | 1675 |
CASP3,SPRED1,RPS6KA1,PSME2,ERBB2,NRG2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,PRKAR2B,AGO4,DUSP4,ITPR3,ABR,IRS2,PLCG1,JAK1,NGFRAP1,HDAC1,NRG1,SPTBN5,GAB1,PCSK5,FGD1,MAPK12,SORT1,TNRC6C,ARHGEF3,ARHGEF11,RASA2,PSMD10,CALM3,PHLPP1,FGF19,ADRBK1,PTEN,MAPK11,ERBB3,NCAM1,RASGRF1,RHOA,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FURIN,ELK1,BCAR1,PSMA4,RASA1,MAPKAPK2,FGFR2,PHLPP2,ITPR1,NFKBIA,GRIN2D,JAK3,ARHGEF9,ARHGEF4 |
| 1.114e-09 | -20.62 | kinase activity | molecular function | GO:0016301 | 775 | 132 | 16491 | 1673 |
LTBP1,NMRK1,AK7,CAMKK1,RET,EPHA4,CAMK1D,CCNB1,DAPK2,WEE1,RPS6KA2,PASK,PAPSS1,DLG1,PIK3CA,PIK3CD,PLK1,ACVR1C,PBK,ROR1,STK17B,CDK1,ADRBK2,LIMK1,PLK2,PIK3C2B,ITPKA,PRKAA2,LMTK3,CDK17,NUAK1,SOX9,DGKQ,ADCK5,TEC,MERTK,BMP2K,IGF1R,DAPK1,MAP3K9,ADCK2,PRKG1,NEK2,ALPK1,PIM1,PIKFYVE,DGKG,MAST4,MMD,ADCK3,TESK1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,PDIK1L,CDK5R1,STK17A,DGKH,MAPKAPK2,PRKAG2,DCK,CSNK1G1,PRPS2,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,PAPSS2,RPS6KA1,ERBB2,TESK2,GRK6,DDR1,PRKACA,CCND1,PLK4,EPHB4,PHKA2,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,RIPK2,PANK1,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,MAPK12,PINK1,CIT,GNE,TGFBR1,TRIB2,PKN1,NRP2,ADRBK1,CDK16,FAM20B,SGK3,SGK1,BUB1,MAPK11,ERBB3,SYK,MPP1,AK4,NADK2,YES1,DGKE,ACVRL1,FGFR2,RYK,PGM2L1,LRRK1,CMPK2,HIPK3,MELK |
| 1.117e-09 | -20.61 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | 198 | 49 | 17758 | 1761 |
IGFBP6,LGALS3,CD63,GALNT12,HEXB,PPFIBP2,ASAH1,KCTD12,IL18,FTH1,CTSZ,TEX2,SLC1A3,SIRPA,TMEM63A,SGPL1,ZFYVE16,TYMP,CA2,CTSC,AIM1,CD9,TMEM51,RAB20,CRY2,PTPRE,SYK,GM2A,CCDC88A,CKAP4,CYP1B1,PDGFC,TIMP2,ALDH2,MMD,PLAUR,SAT1,SLC11A2,TCF7,ATP1B1,FOS,LHFPL2,MSL1,RBM47,SLC2A6,ARRB1,SLC27A3,MAFF,RRAGD |
| 1.117e-09 | -20.61 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 198 | 49 | 17758 | 1761 |
GRN,CCNI,GAA,UPF3B,ZNF395,PSME2,NDRG2,AES,FTH1,F11R,CTSZ,CDKN2C,CTNNBIP1,ADD3,COL6A1,FUT8,CST3,SLC44A1,TMBIM6,HLA-C,TECR,SLC39A10,CTDSP2,LAMP2,ENPP4,SMARCA2,MMD,TNIP1,SH3BGRL,PIK3R1,SYNE2,EZR,NPC2,H2AFV,SESN1,ALCAM,DAG1,GABARAPL1,CNTNAP1,DCTN6,PTPRF,TWSG1,H1F0,SHROOM3,TMC5,DBI,EFNA5,CTSA,NDFIP1 |
| 1.172e-09 | -20.56 | WHITFIELD_CELL_CYCLE_G2 | MSigDB lists | WHITFIELD_CELL_CYCLE_G2 | 168 | 44 | 17758 | 1761 |
CASP3,HJURP,PPP1R2,CKAP2,DCAF7,NDC80,CDCA8,DHX8,KIF23,STIL,LBR,LTBP3,KCTD9,TOP2A,CDKN2C,KIF5B,RGS3,TFAP2A,SORL1,CDKN1B,IQGAP3,NR3C1,BTNL9,CYB5R2,NUSAP1,C2orf69,CDCA2,PIF1,ANLN,CCNF,BORA,KIF11,STK17B,CDK1,TYSND1,G2E3,TRIM69,KBTBD2,FAM83D,UACA,WDR62,UBE2C,ESPL1,MELK |
| 1.225e-09 | -20.52 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9403 | 1048 | 17775 | 1757 |
HECA,AK7,RET,LACTB2,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TMEM37,TIAM1,TIPARP,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,HSPB1,SCN5A,ITGA6,RAB23,TTYH3,ATG4A,TFAP4,FRY,FLRT3,MAP3K9,CADPS2,ALPK1,ZMYM1,DGKG,NUP85,MCCC2,HPS3,ELK1,NPHP3,SFXN5,GNA11,CACHD1,SLC4A4,ETS2,CLMN,GDF11,ADAMTS16,DOCK9,NQO1,C5orf30,GRK6,REPS1,APPBP2,MUC16,ST5,CDH1,XYLT2,ZNF365,ETV4,MYT1,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,XRCC6BP1,GABARAPL1,NFIX,SHROOM3,CDK19,WFS1,AXL,PRIMA1,MAPK12,BTN3A1,CTSZ,DIRAS3,ITGB8,IGSF9,MGAT4A,BAX,IGFBP2,PARP9,ADAMTS2,PLSCR1,PIK3R1,MRS2,CXorf57,UBE2A,CNTNAP1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CR2,SESN1,DZIP1L,TRIM9,PLEKHG6,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,RMND5A,PARP12,RUNX2,HJURP,LGALS3,RASA2,FXYD3,ADCK5,RAB6A,NCKAP1,FBLN1,TNS3,FRAS1,SELK,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,STRADB,SCRIB,PDK3,PRX,COL13A1,PHLPP2,SLC2A6,NLRC5,PLD1,SEMA3A,USP43,CTDSPL,TP53,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,BCL6,CDH3,GLB1L2,NOTCH3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,PTPRJ,ABHD12,RBL1,STK38,EFNA5,SYT13,ZMAT1,BIN1,CMAS,PINK1,CDH22,CPEB4,HAL,ERI2,GTF3A,GDF15,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,GTF2F2,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,RHOA,STMN3,MAML2,GGH,COL7A1,SMTNL2,SCG2,SH3BGRL2,HIPK3,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,SSH1,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,METAP2,SGCE,SPATA18,ACVR1C,KIF13A,LDB2,POR,PRIM1,GDE1,LRIG1,BMP1,PRDM5,NFKBIZ,MRC2,SCOC,TBC1D1,TMEM55B,TNFRSF19,PSIP1,DOPEY2,RALGPS2,ZNRF2,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,ADCK3,LPGAT1,NPC2,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,PELI2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,ST14,CCDC110,RALBP1,THRA,ATP2C2,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,MED30,ATG4D,COG2,PANK1,UTRN,PKMYT1,PYGO1,ATP1B1,ITPR3,ALCAM,ATP10D,FZD7,TSPAN18,ZNF704,SLC27A3,COBL,DEPDC1,IGFBP6,EPS8,HERC5,PBX3,DNAH3,FGF19,SLC25A36,WWP2,E2F7,TMEM87B,FUT8,DRAM1,CD9,CCDC82,ERBB3,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,YES1,GRTP1,FOS,CDK5RAP1,DCTN6,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,DEF6,RGMA,UGT8,VARS2,ERP29,HTR1D,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,SIVA1,ANKFN1,CTTN,MYRIP,SP5,CYP1B1,LAMP3,USP18,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,SP6,CAPN1,PCSK5,NR2C2,LASP1,ARAP3,ZNF395,BVES,PYROXD2,ETV5,ABCG2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,SLC12A2,CCDC88A,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,STEAP1,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,IL27RA,MRAS,OSR2,KCTD9,KIF14,DIXDC1,EPB41L4B,ECE1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,TLE1,SPTBN5,ABCA1,GLIS3,FBLIM1,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,NTAN1,HMGXB4,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,MYCL,BMP7,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,LEPR,FOXL1,ARHGAP24,ENDOD1,SWAP70,RND3,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,AHR,ABCG1,CD33,ACACB,KLK10,ADD1,AASS,DNAJC3,CACNA2D2,NRG2,DHX8,LYNX1,SYTL4,BARD1,CA8,EPDR1,DAPK2,WEE1,AP1M2,PQLC2,PSMD1,KIAA1107,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,ACOX2,SEMA3G,ERAP2,SMARCA2,SPEF2,NWD1,TNIP1,SERTAD4,SH3BGRL,LOXL2,PPP1R14C,CYP4F3,COL12A1,ANKRD6,LIMK1,AGFG2,MRPS28,E2F8,GAB1,HOXC13,FAM169A,ALDH6A1,SLC36A4,MERTK,ELF3,RAVER2,FAM189A1,NEK2,NCAM1,KIF20A,SALL4,STAT4,MYBL2,DCP2,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,ITPR1,AURKA,ARPC2,DRP2,NDE1,ZNF502,EGLN1,XDH,ARHGAP11A,GRHL2,ACTR8,TESK2,PKP2,IL13RA1,NUF2,PRSS22,APC2,PRKACA,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ARL4D,TMEM9,SCN3A,ENPP4,FZD4,CYS1,SYNE2,PLEKHO1,CDCA2,RAB38,IRS2,SIPA1L1,PLEKHG1,INPP4B,TTC8,NKX3-1,PDIA3,ANO9,NUCB2,PKN1,ETS1,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,CALD1,TMBIM6,ADAM15,PLEKHF1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,SNTB1,GALNT3,NR1D2,FHL1,CENPE,MYL9,SIGIRR,TRIM2,FAM199X,GNPDA1,PPM1J,CUL4B,EPHA4,FHDC1,NDC80,PDGFB,CNTRL,MKRN3,DUSP10,TLN2,ANO4,MYBL1,S100A13,NEB,CCDC38,ZNF462,CD55,MCTP1,EZR,ANLN,IDH1,ZBTB7B,RHEB,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,HLA-F,UBASH3B,CNTNAP2,DHRS3,IL18R1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,C9orf9,ABCC1,CHSY3,CYP26B1,TESK1,CORO2A,SPATA13,EIF2AK1,ANKRD29,G2E3,MAPKAPK2,EPN3,COQ10A,PVRL2,H1F0,MFSD2A,CSF1,ITGA7,LTBP2,IFI6,RNF146,UPF3B,UGP2,NF2,FOXM1,XYLT1,ERBB2,LPIN3,RAD23A,PLCG2,SCN2A,DVL2,GM2A,CTH,TMTC1,MBP,FIGNL1,S100A4,CDC20,MYL12A,DUOX1,DNAJC10,PRRT4,ATP1A1,C19orf66,PTK7,ADAMTS14,NDST3,CMTM4,MAN2B2,COL9A3,GOLIM4,MACC1,DAP,RUSC2,SELL,NKRF,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,KLF9,IGDCC4,FAH,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,FUCA1,BANK1,FAT4,ZNF214,TMC5,CDCA7L,NETO2,FAM117A,TBC1D4,DIS3L,GAA,PPP4R4,TTC39B,ATP8A1,TMEM41B,PPFIBP2,PLXNA1,FAM101B,SLC20A1,NCS1,RGS3,STEAP2,AOX1,ATRNL1,MTMR11,PACSIN1,LOC81691,KIFC2,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,CCNF,SAV1,SPNS3,AHRR,SLC25A4,RBM47,GNPTAB,PLK2,NKD1,DHTKD1,UNC5B,TANC2,TRAF5,DDX58,CDK17,MRPL44,FRMD4A,C6orf106,KIF23,SLC1A3,PRRG4,MECOM,ITGA3,PIK3AP1,RUNDC3B,SORL1,RIMS2,FAM69A,IGSF3,EPB41L5,FADS2,B3GNT7,DDB2,MMD,ZNF84,ANO6,AMER1,GLT8D2,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,PLA2G4A,CEP70,NLRX1,S100A11,TRIP10,CAST,IQGAP1,BROX,RNF182,AIFM2,TMPRSS4,MNS1,APLP2,ZNF75D,CDKN1B,CNNM4,DAB2IP,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SP4,NIN,PRDM11,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,CYB561,SEPP1,LGALS3BP,SNTA1,FAM111A,PHF7,PTEN,SGK3,SLC44A2,ATP8B1,SPRY2,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,MAMDC4,AMMECR1,GRIN2D,ETAA1,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,CASP3,LTBP1,CAMKK1,CACNB4,DNER,TMC1,KREMEN1,SH3KBP1,TSEN34,ABCD4,NKAIN3,ARHGEF10L,LRRC6,ZCCHC12,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,SLC39A10,PTPRE,RASGRP1,ROR1,PTGFRN,ADRBK2,EDNRA,ARHGEF19,NEIL1,ADIPOR1,CPPED1,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,KCNN4,RFX5,NCEH1,GYLTL1B,GLCE,XKRX,BCAR3,GNAS,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,GAS2L1,FAM92A1,PSME2,MORC4,LRRC45,SLC25A48,SS18,FRYL,GOT1,TWIST1,RPN2,PDIA6,SCYL3,FRS3,MAP3K3,SUSD3,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,FAM167A,IRF2BPL,IL17RB,MDM1,MLPH,ADORA1,GALNS,KIAA0319,IQGAP3,SYPL1,RAB3B,ASPM,GCLC,NR4A1,LRRC66,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,PRCP,OTUB2,SOX8,GEM,L1CAM |
| 1.309e-09 | -20.45 | regulation of protein phosphorylation | biological process | GO:0001932 | 1334 | 203 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,NRG2,NDRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,CTGF,NPNT,SHC3,IL6ST,RGS3,IL31RA,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,TNIP1,ITCH,PBK,EZR,PRKAR2B,CDK1,KDM4D,ENPP1,PLCG1,GPRC5B,ANKRD6,TRAF3IP1,MADD,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,CDKN1C,UBASH3B,RASA2,SOX9,CALM3,TEC,PHLPP1,FBLN1,MECOM,TFAP4,IGF1R,CYR61,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,CALM1,PDE5A,STRADB,EIF2AK1,EPHA1,PSMA4,RANBP9,RASA1,CDK5R1,FAS,FECH,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,FAM83D,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,CCNE2,SPRED1,AVPI1,NF2,FOXM1,IL15,IQGAP1,PSME2,CTDSPL,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,APLP2,ST5,DACT1,KIF14,CDKN1B,DAB2IP,TWIST1,PDE4D,RASGEF1A,CDKN2D,F2R,CTDSP2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,TIMP2,RIPK2,AKT1,FZD4,PKMYT1,DUSP4,CD40,DAG1,MAP3K6,FZD7,SOCS3,IRS2,DNAJC10,PTPRJ,JAK1,STK26,STK38,CORO1C,SLC27A1,EFNA5,NRG1,SPTBN5,RGS14,PINK1,NKX3-1,SDC4,LRP4,HERC5,PSMD10,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,FGF19,CD109,DIRAS3,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,HES1,PDGFC,RASGRF1,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,MAPK8IP1,CDK5RAP1,BANK1,FGFR2,ACVRL1,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 1.374e-09 | -20.41 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 499 | 93 | 17758 | 1761 |
LZTFL1,HECA,ST14,HEBP1,TESK2,DHX8,SLC20A1,PHLDA1,ERP29,EMP2,CYP39A1,CCND1,HSF2,RPS6KA2,KLF3,FOSB,DLG1,DUSP10,CDH3,TECR,F2R,SULT2B1,SIRT1,TIMP2,CD55,S100A4,SH3BGRL,UTRN,PTGER4,EZR,ERBB2IP,STK17B,FZD7,ABR,IRS2,HLF,KCNK1,NGFRAP1,CORO1C,NOD2,KLF11,ANXA9,HSPB1,F2RL1,PACSIN2,LGALS3,CDKN1C,DNAJB2,ARL4C,ASAH1,PBX3,SEPP1,S100A2,NEO1,CTNNBIP1,FRY,FJX1,OPN3,PIM1,SPRY2,ATP2B1,PDGFC,ALDH2,B3GNT2,PRSS23,TESK1,GUSB,PLAUR,DIAPH2,COL7A1,NFIB,CD83,MAPKAPK2,PTPRF,SLCO4A1,UAP1,PVRL2,FGFR2,SEMA4D,DCK,PELI2,MATN2,DBI,FAM117A,NR4A2,ITGAV,PLD1,FHL1,PER3,HOOK1,PKIA,JARID2,EGLN1 |
| 1.380e-09 | -20.40 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | 193 | 48 | 17758 | 1761 |
ARHGAP11A,CASP3,SPC25,FRMD4A,SERPINE2,ST14,CKAP2,UBASH3B,SLC25A13,ETV5,HMGN3,PHLPP1,FAM81A,CD109,RNF128,TOX2,RANBP1,NEK2,PLK4,BUB1,C12orf75,GCNT1,SYPL1,GCA,PCGF5,MMD,IFITM3,FIGNL1,STAU2,LPGAT1,CORO2A,LITAF,CBX6,DUSP4,C15orf39,PCTP,CD83,OPTN,PLOD2,TIMM8A,MAP2,INPP4B,NCAPG2,HOOK1,CCNB2,NRGN,MELK,STARD3NL |
| 1.380e-09 | -20.40 | GSE7852_TREG_VS_TCONV_LN_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_UP | 193 | 48 | 17758 | 1761 |
UNKL,ATP9A,FRMD6,UBASH3B,CD274,PHLPP1,HDAC9,SNX18,OSBPL3,ZDHHC23,NTN4,MDFIC,TMEM64,LMAN1,RASGEF1A,F2R,SH3BGRL,CORO2A,MPP1,KIF13A,DUSP4,PRKRA,RNPEP,SESN1,CASP4,CD83,ARHGAP24,ENDOD1,SWAP70,BANK1,ACADSB,ANKRD6,TWSG1,AXL,MATN2,LRIG1,FGD6,SERPINB6,NFKBIZ,ITGAV,TANC2,TBC1D4,NR3C2,AHR,MELK,ACOT7,CPPED1,RRAGD |
| 1.385e-09 | -20.40 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 1942 | 276 | 16441 | 1675 |
ACACB,SSH1,AK7,SLC25A13,HEXB,RET,NRG2,PSME1,IL18,CAMK1D,CCNB1,SLC20A1,GRM5,CALM2,DAPK2,WEE1,TYMP,PSMD1,IL31RA,PALD1,SERINC2,PIK3CA,PIK3CD,ACVR1C,PBK,TP53I3,ENPP1,PLCG1,PLK2,LIMK1,GNPTAB,NOD2,DHTKD1,ITPKA,GAB1,CDK17,NUAK1,TMEM55B,DGKQ,SOX9,NDUFA4,ISYNA1,TNFRSF19,MERTK,BMP2K,ATP5H,PPP4R1,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,NCAM1,MAST4,DGKG,MCCC2,GFPT1,PMPCB,MMD,ADCK3,STAT4,LPGAT1,CALM1,PIP4K2C,EPHA1,ELK1,SPTLC2,PSMA4,RASA1,STK17A,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,NRBP1,XDH,PLA2G4A,SPRED1,MTM1,DLGAP5,PAPSS2,INPP5D,RPS6KA1,TESK2,GRK6,PRKACA,DDR1,CDS1,CCND1,DOK4,DAB2IP,PDE4D,EPHB4,PHKA2,RASGEF1A,DLG3,SULT2B1,GPX4,SSH3,RIPK2,PTPN9,PANK1,PRKCQ,ATP1B1,PKMYT1,XRCC6BP1,EPHA10,IRS2,JAK1,CDK19,STK26,AXL,INPP4B,PNPLA6,SLC27A1,NRG1,MLKL,MAPK12,PKN1,PLPPR4,FGF19,PTEN,FAM20B,SGK3,SLC44A2,MAPK11,ERBB3,RASGRF1,SHMT1,PLSCR1,MPP1,RAPGEF2,PIK3R1,GRIN1,AK4,YES1,FOS,GPLD1,FGFR2,ACVRL1,DBI,PPM1H,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,MELK,ACOT7,NMRK1,PPM1J,CAMKK1,EPHA4,PDGFB,CACNB4,SPTB,RPS6KA2,SHC3,IMPAD1,PASK,SLC44A1,PAPL,PAPSS1,DLG1,DUSP10,PTPRE,RASGRP1,PLK1,ROR1,PRKRA,IDH1,ADRBK2,STK17B,CDK1,PLCH1,NEIL1,AGPAT2,DOLPP1,CAB39,PIK3C2B,CPPED1,PRKAA2,LMTK3,RASA2,UBASH3B,CALM3,ADCK5,TEC,PHLPP1,IGF1R,MDFIC,PIM1,PLCB2,MDFI,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,CDK5R1,MAPKAPK2,GNAS,NUDT16,PHLPP2,PLPP3,PRPS2,ALPK3,PLD1,JAK3,UGP2,IL15,PSME2,CTDSPL,ERBB2,LPIN3,PDGFA,PLCG2,PLK4,MINPP1,F2R,SCYL3,CTDSP2,SEPHS1,FRS3,MAP3K3,AKT1,PTPRU,FIGNL1,PTGER4,DUSP4,MAP3K6,ATP1A1,PTPRJ,ALDH5A1,ABHD12,PTK7,STK38,SPTBN5,ST3GAL1,PINK1,ENO2,CIT,GNE,PSMD10,TGFBR1,TRIB2,SBF1,PPP2R3A,ADRBK1,ALPP,CDK16,SGK1,BUB1,IQGAP3,SYK,PGM1,PSMB4,PLAUR,OGDHL,NADK2,RUNX3,MAPK8IP1,DGKE,PRDX4,SCG2,HIPK3 |
| 1.399e-09 | -20.39 | MODULE_52 | MSigDB lists | MODULE_52 | 420 | 82 | 17758 | 1761 |
DLGAP5,HSPG2,EPAS1,NQO1,S100A11,FOXM1,PTTG1,C5orf30,NRG2,CCNB1,SDC1,EMP2,CARD10,CHPF,IER3,EPCAM,CDKN2C,WEE1,GOT1,IFIT1,BTBD3,CKS2,PLK1,SGCE,TIMP2,CENPA,S100A4,CDC20,LOXL2,PKMYT1,CCNF,ITPR3,ALCAM,CDK1,DPYSL3,MDK,PLK2,BMP1,MAFF,GRN,ANXA3,COL9A3,PCOLCE,ITGA6,EPS8,ETV5,GDF15,M6PR,PDIA4,TOP2A,ITGA3,CYR61,CTSC,CALD1,PPP4R1,IGFBP2,ALDH7A1,CITED2,IGSF3,HMMR,FADS2,ZWINT,MMD,PRSS23,PLSCR1,LPGAT1,MYBL2,GGH,KIF11,PSMA4,STEAP1,CYB5A,TIMP3,SWAP70,SERPINA1,PLOD2,RND3,UBE2C,CCNB2,ESPL1,OCLN,PKIA |
| 1.399e-09 | -20.39 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 420 | 82 | 17758 | 1761 |
EXPH5,MYL9,BCAM,UGP2,AASS,CAST,TSC22D3,TMX4,CTDSPL,TAP1,KBTBD11,CDS1,PLS3,PDGFA,CTGF,SP100,EFR3A,PLCG2,PAPSS1,RPN2,IFIT1,F2R,CYP1B1,SEMA3B,SMARCA2,CD55,ING1,HSPA12A,NFE2L1,PTGER4,KLK6,PRKAR2B,GTF2A2,MYL12A,DAG1,RHEB,OPTN,DPYSL3,ALDH3B1,TAPBP,DNM1L,GDE1,HOXA9,AXL,LRIG1,ARF6,MAFF,CDKN1C,ATP9A,GNE,SDC4,PDIA3,HMGN3,TRIB2,VPS26A,DNAJB9,CTNNBIP1,KIF5B,ADD3,ADORA1,ITGA3,FRY,CYR61,BMP7,CALD1,IGFBP2,WWP1,CITED2,PLSCR1,NR3C1,LITAF,BCAR3,UAP1,PLOD2,FGFR2,PVRL2,PHLPP2,NMI,RHOBTB2,KLK7,ITGAV,TOB1 |
| 1.401e-09 | -20.39 | positive regulation of hydrolase activity | biological process | GO:0051345 | 828 | 139 | 16441 | 1675 |
CASP3,RET,ARFGEF1,DNAJB11,F11R,PSME1,ITPR2,DENND2D,CALM2,ARHGEF10L,SIPA1L2,CTGF,NPNT,ARHGEF37,RGS3,RP2,SLC39A10,TIAM1,RASGRP1,ACVR1C,CASP9,ARHGDIB,PRKAR2B,ARF4,ABR,ARHGEF26,EDNRA,PLCG1,PLEKHG6,ARHGEF19,MADD,AGFG2,RAP1GAP,FGD1,ARAP3,TBC1D1,ITGA6,RASA2,CALM3,FBLN1,TFAP4,RALGPS2,CYR61,SNX18,RINL,RANBP1,FAM13B,TBCD,DAPK1,WNT3A,PLCB2,ALS2CL,TBC1D8B,CALM1,SPATA13,SCRIB,EPHA1,PLIN5,RASA1,FAS,RASGRP2,GNAS,BCAR3,SEMA4D,ITPR1,FGD6,ATP1B3,MAP3K5,XDH,DOCK9,ARHGAP11A,IQGAP1,PSME2,RALBP1,RGS20,ERBB2,PRKACA,BCAP31,EPS8L2,ARHGEF16,ACAP2,ST5,SH3BP1,CDKN1B,DAB2IP,RASGEF1A,EGLN3,F2R,GM2A,SIRT1,DOCK4,AKT1,SLC11A2,ATP1B1,ITPR3,CD40,DOCK5,ARHGAP35,DNAJC10,NGFRAP1,CORO1C,SIPA1L1,PLEKHG1,RGS14,MAPK12,ARFGEF3,DENND5B,NKX3-1,PCOLCE,PINK1,ARHGEF3,DEPDC1,ARHGEF11,DAP,SBF1,ARHGEF40,CARD8,ADRBK1,CTSC,LLGL2,BAX,IQGAP3,FARP2,RASGRF1,RHOA,ARHGEF28,ARAP2,PLSCR1,RAPGEF2,GRTP1,GPLD1,ARHGAP24,FGFR2,ARRB1,GPER1,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4 |
| 1.422e-09 | -20.37 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 536 | 98 | 17758 | 1761 |
UGP2,AASS,CRYM,IQGAP1,KCTD12,IL27RA,ISOC2,TP53I11,PJA2,DNER,SDC1,EMP2,ZFYVE9,PDGFA,RAB15,SS18,IL6ST,XYLT2,ALDH1A3,ABCA2,DAB2IP,GLB1L2,RP2,NOTCH3,TIPARP,F2R,PPIF,COL6A2,TIMP2,PRKAR2B,GLO1,LOXL2,ATP1B1,ICMT,C15orf39,PTGFRN,TYSND1,CMTM7,IRS2,GPRC5B,ZNF367,INPP4B,RAB11FIP1,VSIG10,KLF11,ITPKA,REEP4,FRMD4A,OSGIN2,AES,GTF3A,CNTNAP2,SLC1A3,TRIB2,SPR,EFNB1,TSPAN7,NEO1,UBE2Q2,ADRBK1,IGSF9,CTSC,BMP7,COL6A1,TMEM51,FXYD5,CITED2,C12orf75,IGDCC4,PDGFC,HPS3,KIF20A,NR4A1,BCL9,MPP1,YES1,KIF11,ANKRD29,CACHD1,SLCO4A1,SLC6A6,TIMP3,TMEM54,COL13A1,MFSD2A,PRPS2,RYK,FAM83D,RHOBTB2,PITPNA,HMGA1,GDF11,PLOD3,FZD5,COL16A1,HIPK3,PKIA,RUSC1 |
| 1.436e-09 | -20.36 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | 250 | 57 | 17758 | 1761 |
SLC35D2,PACSIN2,TXN,NQO1,ST14,RPS6KA1,DNAJB2,FXYD3,ESRP1,EFHD2,F11R,NANS,GSTP1,SH3KBP1,EPS8L2,SYTL2,MECOM,ELF3,TMEM63A,IER3,CCND1,EPCAM,MLPH,RNF128,FUT2,LLGL2,DOK4,RRBP1,ATP8B1,TACSTD2,ERBB3,EPHB4,BTBD3,S100A6,ACBD5,GFPT1,TNIP1,CRB3,C3orf52,GALNT7,ATP1B1,GRTP1,GNA11,POR,GALNT3,TJP3,TMC5,DBI,DHTKD1,ARRDC1,HDAC1,FAM195A,VSIG10,KLF5,SH3BGRL2,SERPINB1,MYL12B |
| 1.460e-09 | -20.35 | kinase binding | molecular function | GO:0019900 | 576 | 105 | 16491 | 1673 |
CCNE2,SPRED1,SORBS1,FOXM1,DNAJC3,IQGAP1,TP53,PKP2,BCL2L1,CCNB1,PJA2,PRKACA,CACNB4,EMP2,BARD1,ARHGEF16,NCS1,CDKN2C,CALM2,CCND1,SP100,ELMO2,SHC3,DPYSL2,DACT1,ZFP36,KIF14,IL31RA,DLG1,DAB2IP,DLG3,CDKN2D,CHP1,PLK1,DOCK4,SIRT1,AKT1,TNIP1,CASP9,UTRN,EZR,PRKAR2B,RHEB,IRS2,PLCG1,ATP1A1,PTPRJ,GPRC5B,PPP2R5A,STK38,NOD2,PRKCDBP,CAB39,ADIPOR1,NRG1,MLKL,HSPB1,PIFO,SCN5A,PINK1,DGKQ,LRP4,SDC4,SOX9,CALM3,PKN1,TRIB2,GSTP1,HDAC9,TOP2A,ADD3,PTEN,KIF13B,SPRY2,SYK,CCDC88A,SOCS5,KIF20A,CALM1,PIK3R1,RGCC,EPHA1,BCAR1,KIF11,BORA,MAPK8IP1,CDK5R1,FAS,CDK5RAP1,MAPKAPK2,PRKAG2,ACVRL1,RAB11FIP2,FAM83D,NR4A3,ARRB1,AURKA,STK39,ITGAV,MAP3K5,FZD5,PER3,TOB1,TMEM173,PKIA |
| 1.510e-09 | -20.31 | protein kinase binding | molecular function | GO:0019901 | 511 | 96 | 16491 | 1673 |
CCNE2,SPRED1,SORBS1,FOXM1,DNAJC3,IQGAP1,TP53,PKP2,BCL2L1,CCNB1,PJA2,PRKACA,CACNB4,EMP2,ARHGEF16,NCS1,CDKN2C,CALM2,CCND1,ELMO2,SHC3,DPYSL2,DACT1,ZFP36,KIF14,IL31RA,DLG1,DAB2IP,CDKN2D,PLK1,DOCK4,SIRT1,AKT1,TNIP1,CASP9,UTRN,EZR,PRKAR2B,RHEB,IRS2,PLCG1,ATP1A1,PTPRJ,GPRC5B,STK38,NOD2,PRKCDBP,ADIPOR1,NRG1,MLKL,HSPB1,PIFO,SCN5A,PINK1,LRP4,SDC4,SOX9,CALM3,PKN1,TRIB2,GSTP1,HDAC9,TOP2A,ADD3,PTEN,KIF13B,SPRY2,SYK,CCDC88A,SOCS5,KIF20A,CALM1,PIK3R1,RGCC,EPHA1,BCAR1,KIF11,BORA,MAPK8IP1,CDK5R1,CDK5RAP1,MAPKAPK2,PRKAG2,RAB11FIP2,ACVRL1,FAM83D,NR4A3,ARRB1,AURKA,STK39,ITGAV,MAP3K5,FZD5,TOB1,TMEM173,PKIA |
| 1.538e-09 | -20.29 | WANG_SMARCE1_TARGETS_UP | MSigDB lists | WANG_SMARCE1_TARGETS_UP | 270 | 60 | 17758 | 1761 |
MYL9,IER5L,FBLIM1,BCAM,CTHRC1,KIAA1462,ALDH6A1,IGFBP6,HOXB7,EPAS1,ATP9A,GALNT12,LMCD1,IL13RA1,TGFBR1,TRIB2,TNFRSF19,CD109,SIPA1L2,ST5,FRY,ITGB8,SNX18,CALD1,DACT1,FLRT3,FRAS1,TOX2,SLC44A1,PCYOX1,ATP8B1,FAM102A,F2R,WBP5,SULF2,TIMP2,CD55,ROR1,IFIT3,PTGFRN,TCEAL8,ANTXR1,ATP10D,STEAP1,COL12A1,DPYSL3,SOCS3,NUCB1,NGFRAP1,SIPA1L1,MATN2,PGM2L1,HS3ST3B1,UNC5B,LIFR,HIPK3,ABCA1,CYBRD1,KLF7,TLL2 |
| 1.612e-09 | -20.25 | neurotrophin signaling pathway | biological process | GO:0038179 | 397 | 80 | 16441 | 1675 |
CASP3,SPRED1,RPS6KA1,PSME2,ERBB2,NRG2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,PRKAR2B,AGO4,DUSP4,ITPR3,ABR,IRS2,PLCG1,JAK1,NGFRAP1,HDAC1,NRG1,SPTBN5,GAB1,PCSK5,FGD1,MAPK12,SORT1,TNRC6C,ARHGEF3,ARHGEF11,RASA2,PSMD10,CALM3,PHLPP1,FGF19,ADRBK1,PTEN,MAPK11,ERBB3,NCAM1,RASGRF1,RHOA,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FURIN,ELK1,BCAR1,PSMA4,RASA1,MAPKAPK2,FGFR2,PHLPP2,ITPR1,NFKBIA,GRIN2D,JAK3,ARHGEF9,ARHGEF4 |
| 1.613e-09 | -20.25 | membrane-bounded organelle | cellular component | GO:0043227 | 11730 | 1282 | 17570 | 1756 |
HECA,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CMTM6,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIPARP,MGAT5,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,NOD2,HDAC1,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,COX6C,FAM21C,TTYH3,MARCH8,TFAP4,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,ZMYM1,NUP85,PPP6R1,MCCC2,REC8,PQLC3,PYM1,ERO1A,ELK1,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,S100A5,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,NQO1,CD82,PTTG1,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,CDK19,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,DCAF7,ESRP1,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,ITGB8,MGAT4A,FAM20B,CST3,BAX,IGFBP2,MED22,PARP9,ACBD5,PVRL4,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,FANCI,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,TRIM9,HS6ST1,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,RINL,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,WDR44,BCL6,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,SERINC2,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,ZNRF2,BHLHE41,VASN,TPST1,PRKG1,OSTF1,CYSRT1,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,TJP3,FAM64A,FAAH,AGBL5,SFMBT1,CABIN1,KLK7,PLIN3,PER3,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,ST14,THRA,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ITPR3,ALCAM,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,FBXO6,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,CITED2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,DIAPH2,YES1,AIF1L,FOS,ARSK,CPTP,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,EPCAM,RAB15,HSF2,METTL7A,SIVA1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,SNX7,ELK3,VWA1,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TOB1,APOL2,COL16A1,RARG,SNX30,LMO7,CCNE2,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,ECE1,SEPHS1,CHP1,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,ENO2,TSPAN15,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,ENDOD1,CTSL,SWAP70,RND3,TRIM69,CTSV,RAP2C,ARRB1,UACA,MCUR1,ZMIZ1,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,LYNX1,IL18,MORF4L2,SYTL4,BARD1,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,ALDH1A3,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,ARPC2,ZNF502,SERPINB1,EGLN1,XDH,MTM1,CCDC109B,GRHL2,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,ENPP4,SSH3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,SLC9A6,TRABD2A,RGS14,TTC8,NKX3-1,PDIA3,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,ADD3,CTSC,ARSG,ANKS1B,ALG13,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,UNKL,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,ELF5,DUSP10,TRAM1,MYBL1,DDX59,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,ALDH3A2,C9orf9,ABCC1,CYP26B1,CHSY3,MRPS33,PCBP3,SPATA13,TCF7,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,TIMP2,EVA1A,MBP,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,SIRPA,BUB1,ABCD1,KLF9,TLE6,FAH,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,FUCA1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,TMC5,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,CENPN,NCS1,SESN3,CTGF,ZFP36,RGS3,STEAP2,AOX1,MTMR11,PACSIN1,LAMP2,LOC81691,SNTB2,PBK,HSPA12A,CASP9,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,TP53I3,AHRR,HLF,SLC25A4,RBM47,GNPTAB,PTER,FAM110C,DHTKD1,SARAF,MRPL44,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,BDH1,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,MFI2,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,FAS,DGKH,PRKAG2,DCK,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,BROX,KCTD12,CD274,SNN,AIFM2,MNS1,APLP2,ZNF75D,CDKN1B,DAB2IP,LGMN,NR2C1,GPX4,MYO5B,SEC23A,LYRM1,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,HS3ST3B1,NR3C2,WASF3,NUDT6,PCOLCE,ATP9A,ARL4C,CCNJL,APOBEC3H,SEPP1,SPR,LGALS3BP,TEAD3,SIX4,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,NCOA2,SHMT1,PARP4,FURIN,C1GALT1C1,GPLD1,NUCB1,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,HEBP1,CAMKK1,DNER,SH3KBP1,TSEN34,ABCD4,CHPF,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,MRPS36,PTGFRN,STK17B,NEIL1,ZNF114,UEVLD,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,RFX5,NCEH1,LRIF1,KDELR1,OXR1,GYLTL1B,HMG20B,MUM1L1,GLCE,GNAS,FECH,ONECUT1,NUDT16,PLPP3,UTP14C,CDCA5,NFKBIA,ALPK3,PITPNA,PROM2,KLF7,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,ANXA3,SORT1,MIER3,AES,TRMT2B,POMGNT1,IRF2BPL,MDM1,MLPH,ADORA1,GALNS,KIAA0319,SYPL1,SUN2,RAB3B,NR4A1,ASPM,OGDHL,MBNL3,HLA-B,GAREM2,C2orf70,HNRNPH2,PRCP,DHRS2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 1.634e-09 | -20.23 | PEREZ_TP53_TARGETS | MSigDB lists | PEREZ_TP53_TARGETS | 1067 | 166 | 17758 | 1761 |
UNKL,GAA,ILDR1,TRIM2,TSC22D3,CACNA2D2,FAM102B,NRG2,LYNX1,TP53I11,FAM46C,LTBP3,ZNF275,WEE1,SIPA1L2,ELMO2,NPNT,CYP2S1,FUT1,TINAGL1,MARCH2,ANO4,KCNIP3,TRIM8,CELSR2,SPATA18,USP18,HSPA12A,TNS1,CCNF,TP53I3,ADRBK2,CYP4F3,TYSND1,ABR,EDNRA,HS6ST1,GDE1,GNPTAB,ZNF367,TRAF3IP1,UNC5B,GLCCI1,TRAF5,GAB1,LZTS1,HOXC13,GRN,CDKN1C,CHCHD7,NUAK1,BVES,ZCCHC24,ABCG2,HES2,DHRS3,MERTK,KIAA1161,MARCH8,AIM1L,IGF1R,FRY,GATA2,VASN,COL6A1,MDFIC,MYLIP,ULBP2,GAD1,ETV7,TRAK2,KCNJ12,B3GNT7,ADCK3,VWA1,IFIT3,GNA11,C3orf58,FECH,GNAS,COL13A1,SEMA4D,FAM83D,SHROOM2,IFIH1,APOL2,TMEM173,DOCK9,LMO7,FOXO6,GRHL2,GALNT12,CAST,INPP5D,COL18A1,FAM198B,AIFM2,APC2,EPS8L2,APOBEC3B,CYP4F11,DACT1,DOK4,LHX6,REEP1,CNNM4,CDKN1B,GLB1L2,DAB2IP,ESPN,IFIT1,ECE1,EPB41L4B,TMEM64,RASGEF1A,MYT1,ATG4D,DOCK4,ENPP4,MX1,TMEM144,XRCC6BP1,DUOX1,PTPRJ,HS3ST3B1,ANXA9,SLC25A30,LIFR,ABCA1,ISOC1,CMTM4,COL9A3,FBLIM1,CTHRC1,TNRC6C,ENO2,ARHGEF40,FAM167A,SAC3D1,TMEM63A,IRF2BPL,BMP7,LYPD6,TOX2,CST3,KLC3,FAM63A,FAM102A,ATP8B1,ABCD1,ALDH7A1,PVRL4,ADAMTS2,LONRF3,ELOVL3,GRTP1,CRISPLD2,SMTNL2,DHRS2,ABCB1,ARRB1,CMPK2,HIPK3,CYBRD1,ABCG1,ARHGEF4 |
| 1.657e-09 | -20.22 | PH_DOMAIN | prosite domains | PS50003 | 247 | 58 | 11866 | 1235 |
ARAP3,ARHGEF3,ARHGEF11,CIT,RASA2,TEC,SBF1,PHLPP1,ARHGEF40,SPTB,ARHGEF16,SNTA1,ACAP2,ADRBK1,RALGPS2,OSBPL3,PLCG2,EXOC8,PLEKHF1,DAB2IP,RTKN2,CADPS2,TIAM1,FARP2,RASGRF1,ARHGEF28,ARAP2,PLEKHA6,AKT1,SNTB2,PLEKHO1,SPATA13,SNTB1,ANLN,ADRBK2,ABR,ARHGEF26,RASA1,ARHGAP24,IRS2,DGKH,PLCH1,PLCG1,PLEKHG6,SWAP70,ARHGEF19,PLEKHH2,TRIOBP,PLEKHG1,FGD6,SPTBN5,AFAP1,GAB1,ARHGEF9,DEF6,DOCK9,ARHGEF4,FGD1 |
| 1.856e-09 | -20.10 | signaling | biological process | GO:0023052 | 5199 | 638 | 16441 | 1675 |
ADD1,IL15RA,DNAJC3,RET,NRG2,IL18,SYTL4,CA8,CARD10,GRM5,CALM2,DAPK2,PSMD1,CLDN4,CRY2,SEMA3G,PIK3CD,TIAM1,TIPARP,TNIP1,CDA,TFAP2C,PRKAR2B,ARF4,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NUAK1,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,TFAP4,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,NCAM1,DGKG,NUP85,PAQR7,SALL4,STAT4,ERO1A,ELK1,NPHP3,GNA11,PSMA4,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,STK39,GDF11,NDE1,ARPC2,NUP58,DOCK9,ARHGAP11A,NQO1,INPP5D,CD82,PKP2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,RTKN2,ARL4D,DLG3,RAB27B,RASGEF1A,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,IRS2,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,NKX3-1,TNRC6C,SDC4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,SGPL1,CTNNBIP1,DIRAS3,ITGB8,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,AMOTL2,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,CNTNAP1,RAB11FIP2,NR1D2,ACVRL1,SYT7,NR4A3,ITGAV,CENPE,MYL9,SIGIRR,BCAM,EPAS1,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,SHC3,IL6ST,MITF,DUSP10,NTN4,SCARA3,PLK1,THRB,KCNIP3,MCTP1,CELSR2,CR2,EZR,ARFRP1,RHEB,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,HLA-F,RASA2,PDCL,RAB6A,NCKAP1,CNTNAP2,FBLN1,DHRS3,IL18R1,ANO1,IGF1R,KIF13B,SELK,MDFIC,PIM1,WNT3A,PLCB2,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,SCRIB,TCF7,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,NF2,FOXM1,TP53,CCDC68,ERBB2,STIL,BCAP31,SYTL2,IER3,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,NOTCH3,OAS3,SCN2A,CTDSP2,DVL2,SULF2,CTH,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DNAJC10,DUOX1,PTPRJ,IDE,ATP1A1,RBL1,PTK7,STK38,EFNA5,IRF7,ANXA9,SYT13,ZMAT1,PINK1,CPEB4,ADGRG1,DAP,CDCA8,GABRG2,PSMD10,GDF15,CRABP2,AIP,DNAJB9,FZD6,NRP2,PPP2R3A,M6PR,CDK16,SGK1,TRIM21,BUB1,TSPAN13,SYK,DLGAP1,HES1,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,LITAF,PPARA,MAML2,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,FAT4,TWSG1,SCG2,NMI,ICOSLG,NDFIP1,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,LGR4,HSPG2,PSME1,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,ATRNL1,IRF2,TACSTD2,RCAN3,METAP2,ACVR1C,CASP9,AGO4,SAV1,ZFAND5,PLK2,NKD1,EIF4EBP2,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,SLC1A3,TNFRSF19,TSPAN7,MESDC2,ITGA3,RALGPS2,CYR61,PIK3AP1,PPP4R1,PRKG1,OPN3,DAPK1,SORL1,CD70,TNFRSF12A,OSTF1,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,MICB,CALM1,AMER1,ANO6,EPHA1,ANTXR1,RASA1,STX3,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,CABIN1,NR4A2,MAP3K5,IFIH1,SPRED1,REPS2,TCTN2,DLGAP5,TRIP10,S100A11,THRA,RPS6KA1,IQGAP1,RALBP1,CD274,BCL2L1,DDR1,EPS8L2,ZFYVE9,APLP2,NOV,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,LGMN,TSPAN1,MED30,NR2C1,SEMA3B,DOCK4,PRKCQ,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,FZD7,EPHA10,PPP2R5A,JAK1,STK26,NGFRAP1,TSPAN18,SLC27A1,NRG1,NR3C2,ARHGEF3,DEPDC1,IGFBP6,CENPI,EPS8,ARL4C,HERC5,EFNB1,FGF19,LGALS3BP,TEAD3,HLA-A,ADGRB2,RASSF8,E2F7,GNB5,PTEN,FUT8,FJX1,CD9,SGK3,SLC44A2,ERBB3,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ALDH2,ARHGEF28,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,FGFR2,RYK,GRIN2D,LRRK1,GPER1,FZD5,MELK,RGMA,CASP3,LTBP1,CAMKK1,CACNB4,DNER,KREMEN1,TRIM68,PTCHD4,SH3KBP1,HTR1D,EPCAM,ZFYVE16,RAB15,ZCCHC12,TSPAN6,DPYSL2,SIVA1,DLG1,AKR1B1,RAB20,MYH14,CTTN,PTPRE,RASGRP1,CYP1B1,CENPA,TRIM8,ITCH,USP18,ARHGDIB,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,RAP1GAP,NRGN,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,ETV5,ASB9,CALM3,TEC,PHLPP1,CA2,KCNN4,DIAPH2-AS1,C10orf54,HLA-C,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,GNAS,BCAR3,ONECUT1,PLPP3,NFKBIA,RHOBTB2,YOD1,JAK3,TOB1,RARG,COL16A1,SORBS1,SPC25,IL15,PSME2,PDIA5,IL27RA,MRAS,ARHGEF16,SS18,ARTN,KIF14,DIXDC1,GOT1,PDIA6,F2R,FRS3,CHP1,MAP3K3,PTPRU,ERBB2IP,DUSP4,CD40,DOCK5,MAP3K6,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,LIFR,ABCA1,SORT1,ARHGEF11,CIT,LRP4,TGFBR1,AES,NOTUM,HMGXB4,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,IQGAP3,MYO5A,SYPL1,RAB3B,NR4A1,DEPDC4,LEPR,FOXL1,ARHGAP24,CTSL,HLA-B,RND3,RAP2C,DTX4,UACA,ARRB1,GEM,SOX8,L1CAM,AHR,CD33,SNPH |
| 1.868e-09 | -20.10 | stomach | COSMIC cancer mutations | stomach | 16373 | 1678 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,ARF6,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,NR3C1,AMFR,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.952e-09 | -20.05 | neuron projection guidance | biological process | GO:0097485 | 562 | 103 | 16441 | 1675 |
MYL9,SPRED1,PSME2,RPS6KA1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,ARTN,SHC3,DPYSL2,DLG1,TRPC1,DAB2IP,NTN4,MYH14,EPHB4,DLG3,RASGEF1A,TIAM1,ETV4,RASGRP1,FRS3,SEMA3B,COL6A2,EZR,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,DPYSL3,EPHA10,IRS2,PLCG1,JAK1,LIMK1,SPTBN5,NRG1,EFNA5,UNC5B,MYL12B,SCN5A,COL9A3,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,FGF19,EFNB1,NRP2,NEO1,KIF5B,BMP7,FLRT3,COL6A1,ERBB3,CACNA1D,NCAM1,WNT3A,FARP2,DPYSL5,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,RANBP9,PSMA4,NFIB,CDK5R1,RASA1,CNTNAP1,FGFR2,SEMA4D,MATN2,RYK,NR4A3,PGRMC1,PITPNA,GRIN2D,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 1.952e-09 | -20.05 | axon guidance | biological process | GO:0007411 | 562 | 103 | 16441 | 1675 |
MYL9,SPRED1,PSME2,RPS6KA1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,ARTN,SHC3,DPYSL2,DLG1,TRPC1,DAB2IP,NTN4,MYH14,EPHB4,RASGEF1A,DLG3,TIAM1,ETV4,RASGRP1,FRS3,SEMA3B,COL6A2,EZR,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,DPYSL3,EPHA10,IRS2,PLCG1,JAK1,LIMK1,SPTBN5,NRG1,EFNA5,UNC5B,MYL12B,SCN5A,COL9A3,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,FGF19,EFNB1,NRP2,NEO1,KIF5B,BMP7,FLRT3,COL6A1,ERBB3,CACNA1D,NCAM1,WNT3A,FARP2,DPYSL5,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,RANBP9,PSMA4,NFIB,CDK5R1,RASA1,CNTNAP1,FGFR2,SEMA4D,MATN2,RYK,NR4A3,PGRMC1,PITPNA,GRIN2D,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 2.043e-09 | -20.01 | neuron projection morphogenesis | biological process | GO:0048812 | 741 | 127 | 16441 | 1675 |
MYL9,EMX1,SPRED1,UGT8,PSME2,RPS6KA1,IQGAP1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,PDGFA,CALM2,WEE1,RPS6KA2,PSMD1,ARTN,SHC3,DPYSL2,DACT1,DLG1,TRPC1,DAB2IP,NTN4,MYH14,CTTN,EPHB4,PACSIN1,RASGEF1A,DLG3,BTBD3,ETV4,TIAM1,RASGRP1,FRS3,SEMA3B,ATL1,COL6A2,CELSR2,EZR,PRKCQ,SLC11A2,ALCAM,DAG1,MYL12A,ARHGAP35,DPYSL3,EPHA10,IRS2,PLCG1,JAK1,MAP2,LIMK1,SLC9A6,SPTBN5,NRG1,EFNA5,UNC5B,LIFR,COBL,MYL12B,SCN5A,COL9A3,ARHGEF11,RASA2,LRP4,CALM3,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,NEO1,KIF5B,IGF1R,PTEN,BMP7,FLRT3,COL6A1,SGK1,ERBB3,CACNA1D,NCAM1,WNT3A,S100A6,FARP2,DPYSL5,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,FMN1,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,RANBP9,NFIB,PSMA4,RASA1,CDK5R1,CNTNAP1,FGFR2,SEMA4D,MATN2,RYK,NR4A3,PGRMC1,AURKA,PITPNA,GRIN2D,NR4A2,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 2.078e-09 | -19.99 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15558 | 1612 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,MX1,SEC61B,COL6A2,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,HABP4,SDC4,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,DDOST,POPDC3,TSPAN18,ZNF704,FAM195A,SLC27A3,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,MPP5,ERP29,TRIM68,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,ENDOD1,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,PSMD10,NKRF,DSE,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,NLRX1,BROX,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.087e-09 | -19.99 | CERVERA_SDHB_TARGETS_2 | MSigDB lists | CERVERA_SDHB_TARGETS_2 | 108 | 33 | 17758 | 1761 |
CCNE2,SERPINE2,NUAK1,UBASH3B,ESRP1,CYB561,ITPR2,TNFRSF19,HDAC9,SIPA1L2,CYR61,METTL7A,LYPD6,AIM1,TFAP2A,CADPS2,NOTCH3,SLC12A2,PRSS23,MFI2,SH3BGRL,MICB,COL7A1,STEAP1,LEPR,STK17A,GALNT3,GPRC5B,MATN2,NMI,SERPINI1,LTBP2,HS3ST3B1 |
| 2.161e-09 | -19.95 | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | MSigDB lists | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | 1587 | 228 | 17758 | 1761 |
EXPH5,BCAM,PPP4R4,KLK10,TTC39B,CRYM,CPT2,TMEM41B,EPHA4,NDC80,FBXO2,TP53I11,HDAC6,DENND2D,ZFYVE16,SESN3,ZNF823,CNTRL,METTL7A,ARHGEF37,POF1B,SNX16,NTN4,RP2,SEMA3G,RNF26,PLK1,CELSR2,ITCH,RGAG1,CDA,NFE2L1,MTRF1L,KIF13A,CYP4F3,CARHSP1,RBM47,HPSE,WIPI1,MAP2,KCNK1,DOLPP1,LRIG1,BMP1,AGFG2,SERPINI1,TMOD2,PIEZO1,TANC2,EPB41L4A,GLCCI1,E2F8,PCSK5,MRC2,NUAK1,BVES,DNAJB2,MTL5,RAB23,KIF23,ISYNA1,SLC1A3,CNTNAP2,PHLPP1,TSPAN7,PSIP1,PRRG4,MARCH8,ZNF432,TNS3,CA2,IGF1R,PAIP2B,KIF13B,EXOC8,NEK2,TMEM51,DAPK1,MAP3K9,RFX5,C10orf54,ALPK1,LRIF1,GAD1,MAST4,C9orf72,SYTL3,MPHOSPH9,RIMS2,MCCC2,CYP26B1,DDB2,KLK5,KIF20A,TBC1D8B,STAT4,BTN3A2,RNF113A,TP53INP2,GLT8D2,ANKRD29,FECH,XKRX,EPN3,CACHD1,UAP1,FAM64A,H1F0,CSF1,NFKBIA,FAM83D,CLMN,CDK18,KLK7,STK39,PLD1,PER3,ZNF502,HOOK1,IFIH1,CCNB2,RARG,APOL2,RNF146,EGLN1,LZTFL1,PAPSS2,DLGAP5,TCTN2,CD82,RGS20,TESK2,NUF2,SNN,PRKACA,EMP2,DDR1,TMPRSS4,ZNF385B,SYTL2,CCND1,PDGFA,ZNF75D,KIF14,BCL6,DAB2IP,IFIT1,PDE4D,ARL4D,TSPAN1,F2R,SULT2B1,CTDSP2,CTH,APOBEC3D,S100A4,SYNE2,SERTAD3,SLC11A2,NUSAP1,KCTD2,ZNF618,GABARAPL1,ALDH3B1,STK38,OVOL1,EFNA5,REEP4,ZNF701,CBX7,CMTM4,PINK1,CPEB4,KLHL13,CKAP2,TSPAN15,POC1B,ARMC7,BLVRB,HABP4,MIER3,NKRF,GDF15,HMGN3,COL4A5,CRABP2,H1FX,HDAC9,DTX3L,CXCL16,ADD3,TMEM87B,ALPP,LLGL2,FAM63A,TFAP2A,DRAM1,ATP8B1,KLF9,ERBB3,C12orf75,PARP9,PDGFC,ASPM,PIK3R1,LRRC66,MBNL3,PRICKLE1,DIAPH2,FBXO9,LRRC1,BBS2,KIF11,KLHL2,ARHGAP24,RPL12,TIMP3,FAT4,ACADSB,FGFR2,TRIM69,CLIP4,UACA,CENPE,ZMIZ1,CYBRD1,CXorf56,GOLGB1 |
| 2.206e-09 | -19.93 | DODD_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_UP | 1528 | 221 | 17758 | 1761 |
EXPH5,SUN1,SIGIRR,KLK10,TTC39B,EPAS1,CRYM,AK7,CAMKK1,FHDC1,NDRG2,IL18,SYTL4,DNER,GRM5,AP1M2,RPS6KA2,LRRC6,CTGF,ARHGEF37,STIM1,TSPAN6,ZFP36,ALDH1A3,ANKFN1,SERINC2,IQCD,TACSTD2,CRY2,MYH14,RCAN3,SCARA3,SMAGP,THRB,ATL1,ORAI2,SPEF2,CD55,SPATA18,SERTAD4,CASP9,EZR,SLC35C1,CR2,TNS1,STK17B,SPNS3,POR,DZIP1L,PIAS3,NEIL1,HLF,AGPAT2,TRAF3IP1,RAB11FIP1,AGFG2,PIK3C2B,SERPINB6,WBSCR27,GAB1,MYL12B,CPPED1,PCSK5,PRKAA2,ZNF395,LGALS3,CDKN1C,DNAJB2,TMEM55B,PHLPP1,DHRS3,TNFRSF19,KIAA1161,ELF3,OTUD1,AIM1L,DOPEY2,RALGPS2,FLRT3,KIF13B,BHLHE41,BDH1,RUNDC3B,MAP3K9,C10orf54,ALS2CL,ALDH3A2,C9orf72,PPP6R1,C9orf9,PAQR7,REC8,B3GNT7,KCNJ12,ELK3,PCDH1,PLEKHA6,SLC37A1,PRSS23,PCBP3,SPTLC2,TP53INP2,GNA11,FRMD4B,DHX32,RASGRP2,FECH,EPN3,MMP15,SLC6A6,COQ10A,TJP3,SETD3,RHOBTB2,SFMBT1,CLMN,PITPNA,NR4A2,TMEM120A,PLIN3,SERPINB1,DOCK9,USP43,LMO7,LZTFL1,SLC25A24,NQO1,TCTN2,NLRX1,ST14,CAST,THRA,GALNT12,ATP2C2,ERBB2,PRSS22,GRK6,MNS1,TMPRSS4,CYP39A1,SYTL2,EPS8L2,CDS1,APLP2,MUC16,SCNN1A,ENPP5,REEP1,BCL6,DIXDC1,EPB41L4B,LRP11,TSPAN1,CTH,MYO5B,ENPP4,MBP,PTPRU,SAT1,RAB38,DUOX1,ALDH3B1,PPP2R5A,WFS1,SIPA1L1,KLF5,SLC27A1,ANXA9,RGS14,CBX7,COBL,PRR15,GCLM,SORT1,PINK1,GNE,EFHD2,CYB561,GDF15,NUCB2,DNAH3,SRPX2,WWP2,MLPH,ADORA1,PHF7,SLC27A6,FUT2,LLGL2,A4GALT,KIAA0319,FAM63A,FAM102A,TPCN1,SLC16A5,S100A6,FARP2,AMOTL2,PVRL4,HES1,LCA5,FMN1,AMFR,RAPGEF2,SYBU,MYEOV,DIAPH2,TTC7A,BCAR1,SCRN2,C2orf70,ZNF214,TMC5,ABCB1,DTX4,CCDC69,CSTF2,CLIP4,SH3BGRL2,FHL1,GRAMD1C |
| 2.228e-09 | -19.92 | AMUNDSON_GAMMA_RADIATION_RESPONSE | MSigDB lists | AMUNDSON_GAMMA_RADIATION_RESPONSE | 41 | 19 | 17758 | 1761 |
PLK1,CENPA,PTTG1,KIF23,CCNF,CCNB1,CDK1,LBR,CDKN2C,WEE1,PPP2R5A,NEK2,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,CKS2 |
| 2.317e-09 | -19.88 | single organism signaling | biological process | GO:0044700 | 5196 | 637 | 16441 | 1675 |
ADD1,IL15RA,DNAJC3,RET,NRG2,IL18,SYTL4,CA8,CARD10,GRM5,CALM2,DAPK2,PSMD1,CLDN4,CRY2,PIK3CD,SEMA3G,TIAM1,TIPARP,TNIP1,CDA,TFAP2C,PRKAR2B,ARF4,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NUAK1,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,TFAP4,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,NCAM1,DGKG,NUP85,PAQR7,SALL4,STAT4,ERO1A,NPHP3,ELK1,PSMA4,GNA11,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,STK39,GDF11,NDE1,ARPC2,NUP58,DOCK9,ARHGAP11A,NQO1,CD82,INPP5D,PKP2,IL13RA1,NUF2,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,RTKN2,ARL4D,DLG3,RASGEF1A,RAB27B,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,IRS2,SLC9A6,CORO1C,WFS1,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TNRC6C,NKX3-1,SDC4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,SGPL1,CTNNBIP1,DIRAS3,ITGB8,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,AMOTL2,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,CNTNAP1,ACVRL1,NR1D2,SYT7,RAB11FIP2,NR4A3,CENPE,ITGAV,MYL9,SIGIRR,BCAM,EPAS1,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,SHC3,IL6ST,MITF,DUSP10,NTN4,SCARA3,THRB,PLK1,KCNIP3,MCTP1,CELSR2,CR2,EZR,ARFRP1,RHEB,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,NCKAP1,RAB6A,CNTNAP2,FBLN1,DHRS3,ANO1,IL18R1,IGF1R,KIF13B,SELK,MDFIC,PIM1,WNT3A,PLCB2,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,TCF7,SCRIB,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,NF2,FOXM1,TP53,ERBB2,CCDC68,STIL,BCAP31,SYTL2,IER3,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,CTH,SULF2,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,PTK7,STK38,IRF7,EFNA5,ANXA9,SYT13,ZMAT1,PINK1,CPEB4,ADGRG1,DAP,CDCA8,GABRG2,PSMD10,GDF15,CRABP2,AIP,FZD6,PPP2R3A,DNAJB9,NRP2,M6PR,CDK16,SGK1,TRIM21,BUB1,TSPAN13,SYK,DLGAP1,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,FAT4,SCG2,TWSG1,NMI,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,TXN,LGR4,HSPG2,PSME1,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,ATRNL1,IRF2,TACSTD2,RCAN3,METAP2,ACVR1C,CASP9,AGO4,SAV1,ZFAND5,PLK2,NKD1,EIF4EBP2,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,SLC1A3,TNFRSF19,TSPAN7,MESDC2,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,PRKG1,OPN3,DAPK1,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,MICB,CALM1,ANO6,AMER1,EPHA1,ANTXR1,STX3,RASA1,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,CABIN1,NR4A2,MAP3K5,IFIH1,SPRED1,REPS2,TCTN2,S100A11,TRIP10,RALBP1,THRA,IQGAP1,RPS6KA1,BCL2L1,CD274,DDR1,EPS8L2,ZFYVE9,APLP2,NOV,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,LGMN,MED30,NR2C1,SEMA3B,DOCK4,PRKCQ,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,FZD7,EPHA10,JAK1,PPP2R5A,NGFRAP1,STK26,TSPAN18,SLC27A1,NRG1,NR3C2,ARHGEF3,DEPDC1,IGFBP6,CENPI,EPS8,ARL4C,HERC5,EFNB1,FGF19,LGALS3BP,ADGRB2,HLA-A,TEAD3,RASSF8,E2F7,GNB5,PTEN,FJX1,FUT8,CD9,SGK3,SLC44A2,ERBB3,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ALDH2,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,FGFR2,RYK,GRIN2D,GPER1,LRRK1,FZD5,MELK,RGMA,LTBP1,CASP3,CAMKK1,DNER,CACNB4,TRIM68,KREMEN1,PTCHD4,SH3KBP1,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,DPYSL2,SIVA1,TSPAN6,DLG1,AKR1B1,RAB20,CTTN,MYH14,PTPRE,RASGRP1,CYP1B1,TRIM8,CENPA,USP18,ITCH,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,MDK,CXXC4,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,NRGN,RAP1GAP,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,ETV5,ASB9,CALM3,TEC,PHLPP1,CA2,KCNN4,DIAPH2-AS1,HLA-C,C10orf54,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,BCAR3,GNAS,ONECUT1,PLPP3,NFKBIA,RHOBTB2,YOD1,JAK3,COL16A1,RARG,TOB1,SORBS1,SPC25,IL15,PSME2,PDIA5,MRAS,IL27RA,ARHGEF16,SS18,ARTN,KIF14,GOT1,DIXDC1,F2R,PDIA6,CHP1,FRS3,MAP3K3,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CASP4,MAP3K6,SOCS3,ARHGAP35,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LIFR,SORT1,ARHGEF11,CIT,LRP4,AES,TGFBR1,NOTUM,HMGXB4,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,IQGAP3,MYO5A,SYPL1,RAB3B,DEPDC4,NR4A1,FOXL1,LEPR,CTSL,ARHGAP24,HLA-B,RND3,RAP2C,DTX4,ARRB1,UACA,GEM,SOX8,AHR,L1CAM,CD33,SNPH |
| 2.353e-09 | -19.87 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13367 | 1420 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,DPP8,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,PAQR5,TMEM37,TIAM1,TIPARP,MGAT5,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,TMEM159,TMEM173,RUSC1,DOCK9,NQO1,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,XRCC6BP1,GTF2A2,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,HABP4,SDC4,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,CDK5R1,PRX,RASGRP2,KBTBD2,PHLPP2,P4HA3,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,NANS,VASH1,OAT,PJA2,SLC9A7,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,PIK3CA,IRF2,SNX16,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KLK5,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,THRA,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,TSPAN1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,DDOST,ZNF704,FAM195A,COBL,CBX7,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,DNAH3,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,PDGFC,ZWINT,ARHGEF28,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,TRPC1,MYRIP,BTBD3,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,LASP1,ARAP3,PPP1R2,ZNF395,BVES,PYROXD2,ETV5,ABCG2,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,HMGXB4,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,RC3H2,TTC7A,RUNX3,ENDOD1,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,PIK3CD,TINAGL1,ACOX2,ERAP2,NWD1,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SLC36A4,MERTK,LMNA,RAVER2,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,FHL1,USF2,DCBLD1,CYBRD1,MYL9,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,ZCCHC24,UBASH3B,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,LPIN3,RAD23A,ATP6V0B,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,PRRT4,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SIRPA,PPP2R3A,SLC9A2,CCDC92,ABCD1,BUB1,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,FAM101B,SLC20A1,NCS1,SESN3,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,UNC5B,TANC2,TRAF5,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,PRRG4,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,IFIT1,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,PCOLCE,ATP9A,CCNJL,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,CPT2,HEBP1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,LRRC6,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,ZNF114,NEIL1,ADIPOR1,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,LRIF1,ALS2CL,KDELR1,OXR1,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,NFKBIA,RHOBTB2,ALPK3,YOD1,PITPNA,EGFL7,KLF7,PROM2,SPC25,FAM92A1,IL15,TDRKH,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,OVOL1,VSIG10,CYP2U1,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,IL17RB,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,GCLC,DEPDC4,ASPM,MBNL3,LRRC66,OGDHL,KLHL2,C2orf70,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.395e-09 | -19.85 | cellular response to chemical stimulus | biological process | GO:0070887 | 2460 | 335 | 16441 | 1675 |
SSH1,ADD1,IL15RA,DNAJC3,RET,NRG2,PSME1,IL18,CCNB1,CALM2,CYP1A1,PSMD1,CTGF,ELMO2,CYP2S1,IL31RA,KLF3,FOSB,PIK3CA,IRF2,PIK3CD,TIAM1,TIPARP,CASP9,AGO4,PRKAR2B,CYP4F3,POR,ABR,ENPP1,PLCG1,NOD2,HDAC1,EIF4EBP2,HSPB1,GAB1,FGD1,SCN5A,HLA-E,SOX9,TNFRSF19,LMNA,TFAP4,MEGF8,FLRT3,VASN,DAPK1,TNFRSF12A,CD70,MYDGF,NCAM1,NUP85,SOCS5,PAQR7,EPB41L5,GFPT1,PRODH,STAT4,CALM1,ANO6,ERO1A,ELK1,PSMA4,RASA1,FAS,NCOA3,PRKAG2,ITPR1,NR4A2,MAP3K5,NUP58,TMEM173,EGLN1,EHD1,PLA2G4A,SPRED1,SLC2A4,NQO1,PAPSS2,THRA,RPS6KA1,IQGAP1,IL13RA1,MGST2,BCL2L1,PRKACA,CYP39A1,ZFYVE9,CCND1,NOV,ACAP2,CDH1,SP100,CDKN1B,DAB2IP,PDE4D,IFIT1,RASGEF1A,SULT2B1,NR2C1,MX1,DOCK4,SEC61B,RIPK2,FZD4,PRKCQ,SLC11A2,ITPR3,FZD7,IRS2,ALDH3B1,JAK1,CDK19,NGFRAP1,WFS1,AXL,SLC27A1,NRG1,NR3C2,MAPK12,ARHGEF3,TNRC6C,NKX3-1,HERC5,ETS1,GSTP1,FGF19,HLA-A,CXCL16,PTEN,CST3,FUT8,BAX,CD9,IGFBP2,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,NCOA2,OPLAH,RASGRF1,TGIF1,PDGFC,ALDH2,SHMT1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,TIMP3,PLOD2,FGFR2,RAB11FIP2,NR1D2,ACVRL1,NR4A3,OSER1,GRIN2D,GPER1,CMPK2,OSR1,USF2,CPEB2,MELK,RGMA,CASP3,UGT8,EPAS1,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,TRIM68,SPTB,ZFYVE16,CPNE2,RPS6KA2,NPNT,SHC3,ZCCHC12,IL6ST,PAPSS1,AKR1B1,RASGRP1,SP5,CYP1B1,THRB,TRIM8,USP18,NFE2L1,EZR,PRKRA,RHEB,DPYSL3,WIPI1,MAP2,MADD,CAB39,ADIPOR1,NR2C2,PCSK5,RRAGD,PRKAA2,RUNX2,LGALS3,HLA-F,RASA2,ETV5,CALM3,PHLPP1,IL18R1,IGF1R,COL6A1,AHCY,PIM1,C10orf54,HLA-C,WNT3A,CYP26B1,RGMB,OXR1,STRADB,TCF7,PDK3,IFIT3,RASGRP2,GNAS,FECH,MAPKAPK2,PHLPP2,CSF1,NFKBIA,SH3BP4,YOD1,LTBP2,JAK3,IFI6,RARG,COL16A1,GAS2L1,SLC25A24,SORBS1,UGP2,IL15,PSME2,PDIA5,TP53,ERBB2,IL27RA,ARHGEF16,CYP26A1,PDGFA,ATP6V0B,CYP4F11,TWIST1,GOT1,OAS3,EGLN3,PDIA6,CTDSP2,FRS3,CTH,PPIF,SIRT1,TIMP2,AKT1,ERBB2IP,DUSP4,CD40,CASP4,ATP13A2,SOCS3,DUOX1,ATP1A1,IDE,RBL1,PTK7,IRF7,SPTBN5,CYP2U1,LIFR,ABCA1,GCLM,PINK1,SORT1,CPEB4,ARHGEF11,LRP4,PSMD10,GABRG2,TGFBR1,GDF15,AIP,DNAJB9,NRP2,HDAC9,IL17RB,ADRBK1,BMP7,TFAP2A,TRIM21,KLF9,IQGAP3,SYK,MYO5A,RHOA,PSMB4,NR3C1,IFITM3,GCLC,NR4A1,AMFR,LITAF,RGCC,PPARA,BBS2,BCAR1,LEPR,CTSL,HLA-B,SCG2,TWSG1,NAT1,DHRS2,PLOD3,TBC1D4,ARHGEF9,AHR,ARHGEF4 |
| 2.545e-09 | -19.79 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 280 | 61 | 17758 | 1761 |
SLC25A24,MRC2,PAPSS2,GNPDA1,CALB2,XYLT1,COL4A5,IL27RA,HMGN3,SYTL4,CCNB1,COX6C,EMP2,ZNF385B,IL17RB,APLP2,ADD3,ADORA1,IGF1R,SLC27A6,TSPAN6,SGK3,ADCK2,ATRNL1,RFX5,TECR,MYBL1,C12orf75,TIPARP,DVL2,CYP1B1,SUSD3,LAMP2,CELSR2,PRSS23,TNIP1,KIF20A,AMFR,PIK3R1,SYBU,PARP4,AK4,TFAP2C,STMN3,F12,SAV1,TP53I3,PLIN5,CYB5A,IRS2,TMEM164,KCNMB4,PPP2R5A,PDLIM3,TRIM69,P4HA2,LRIG1,RAP2C,DHTKD1,SLC27A3,JARID2 |
| 2.681e-09 | -19.74 | BILD_HRAS_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_HRAS_ONCOGENIC_SIGNATURE | 241 | 55 | 17758 | 1761 |
TTC8,GRHL2,EPHA4,SDC4,GDF15,HMGN3,CD274,SLC20A1,SDC1,PHLDA1,EFNB1,IER3,PDGFA,C7orf49,ST5,KCNN4,ZFP36,FLRT3,BCL6,TNFRSF12A,PIK3CD,PIM1,PTPRE,MAST4,ULBP2,S100A6,ATP2B1,CYP1B1,PPIF,CD55,ELK3,PLAUR,FBXO9,DUSP4,ITPR3,LHFPL2,FOS,NFIB,COL12A1,HPSE,UAP1,FGFR2,KCNK1,MFSD2A,FAM110C,KLF5,MDH1,NFKBIZ,GLCCI1,SERPINB1,ARHGEF9,TOB1,ABCA1,ACOT7,EHD1 |
| 2.755e-09 | -19.71 | caecum | COSMIC cancer mutations | caecum | 14975 | 1562 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,ZNF365,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,AK4,CNTNAP1,PLOD2,RAB11FIP2,SYT7,DBI,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,SYTL2,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,AIP,LBR,PARM1,H1FX,NRP2,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,TFAP2A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,ACAP2,TRANK1,EPHB4,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,ABCG1,CD33,ACACB,KLK10,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,RELL1,GAB1,E2F8,FAM169A,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,HMGA1,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,H1F0,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,FADS2,B3GNT7,MFI2,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,GRHL1,ZCCHC12,DPYSL2,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,UTP14C,NFKBIA,ALPK3,RHOBTB2,YOD1,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.825e-09 | -19.68 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16643 | 1698 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.861e-09 | -19.67 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | 197 | 48 | 17758 | 1761 |
GAA,IL15RA,UBASH3B,PBX3,TGFBR1,TRMT2B,NCKAP1,NUCB2,LTBP3,IL17RB,ITGA3,CYP2S1,KIF13B,OSBPL3,CD70,MDFIC,MTMR11,F2R,TRAM1,C9orf72,GCNT1,LAMP2,LOC81691,TIMP2,S100A4,TFAP2C,PRICKLE1,FAM133B,PRKAR2B,RNF19B,ALCAM,C3orf58,ANKRD29,FRMD4B,AHRR,ENPP1,PTPRJ,KLF12,HPSE,ANKRD6,AXL,CSF1,S100A5,FGD6,SPCS3,PER3,NIPA1,EHD1 |
| 2.962e-09 | -19.64 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | 191 | 47 | 17758 | 1761 |
RMND5A,FBLIM1,RASA2,HDAC11,SELL,IL18,IL27RA,SYTL4,DNER,IL18R1,LTBP3,DNAJB9,RASSF8,SESN3,RPS6KA2,SCNN1A,CA2,FAM13B,SLC44A1,N4BP3,PIK3CA,BCL6,FAM102A,MDFIC,KLF9,ECE1,ERBB3,MYLIP,SPRY2,C9orf72,NR3C1,USP18,KIF1C,KCTD2,STK17B,IRS2,MMP15,EPN3,HLA-B,GPRC5B,NR1D2,HOXA9,WFS1,RELL1,GAB1,ABCA1,JARID2 |
| 2.967e-09 | -19.64 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 499 | 92 | 17758 | 1761 |
FOXO6,SLC25A24,UPF3B,NQO1,FOXM1,FAM199X,ST14,VANGL1,TRIP10,GNPDA1,NUF2,GRK6,PLXNA1,BARD1,PDGFA,NPNT,PAQR5,SERINC2,TRPC1,TWIST1,SLC39A10,LRP11,RCAN3,TMEM200B,ORAI2,KIFC2,CBX6,TFAP2C,ITPR3,KCTD2,PTGFRN,ZNF618,ATP13A2,PGF,ANKRD10,DNAJC10,GPRC5B,DDOST,POPDC3,DNM1L,MAP2,ZNF704,HDAC1,VSIG10,TRAF5,RRAGD,PCSK5,CTHRC1,LASP1,FBLIM1,PACSIN2,SORT1,ENO2,CDKN1C,SERPINE2,HJURP,FXYD3,SOX9,INTS8,FBLN1,SAC3D1,PDIA4,SLC25A36,MECOM,CD109,ZNF432,B3GALNT1,CARD8,UBE2Q2,CTSC,MYLIP,MPHOSPH9,CKAP4,IGSF3,MMD,NUB1,MRS2,MYBL2,SCRIB,GNAS,AMMECR1,CDCA7L,SLC2A6,NETO2,ALPK3,STK39,HMGA1,PLD1,NDE1,SERPINB1,PTGES,DEF6 |
| 3.075e-09 | -19.60 | regulation of transferase activity | biological process | GO:0051338 | 986 | 158 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,NRG2,PSME1,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,CDKN2C,PSMD1,SHC3,RGS3,SERINC2,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,PRKAR2B,PIF1,CDK1,PLCG1,GPRC5B,LIMK1,MADD,NOD2,CAB39,HSPB1,GAB1,PIFO,CDKN1C,RASA2,UBASH3B,CALM3,TFAP4,IGF1R,CYR61,NEK2,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,CALM1,STRADB,PDE5A,EPHA1,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,CSF1,NLRC5,STK39,MAP3K5,JAK3,CCNE2,SPRED1,AVPI1,NF2,GRHL2,IQGAP1,PSME2,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,APLP2,KIF14,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,F2R,DVL2,FRS3,CHP1,CKS2,MAP3K3,SIRT1,AKT1,RIPK2,FZD4,CDC20,PRKCQ,PKMYT1,DUSP4,CD40,MAP3K6,SOCS3,IRS2,PTPRJ,PPP2R5A,JAK1,STK26,RBL1,STK38,CORO1C,SLC27A1,NRG1,SPTBN5,EFNA5,RGS14,NKX3-1,PINK1,SDC4,HERC5,PSMD10,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,PARM1,DIRAS3,ADORA1,PTEN,BMP7,BAX,BUB1,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,PSMB4,RAPGEF2,PIK3R1,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,RAP2C,ARRB1,PPP2R3C,GRIN2D,CENPE,FZD5,UBE2C,HIPK3,PKIA |
| 3.099e-09 | -19.59 | phosphorus metabolic process | biological process | GO:0006793 | 2000 | 281 | 16441 | 1675 |
ACACB,SSH1,AASS,AK7,SLC25A13,HEXB,RET,NRG2,PSME1,IL18,CAMK1D,CCNB1,SLC20A1,GRM5,CALM2,DAPK2,WEE1,TYMP,PSMD1,IL31RA,PALD1,SERINC2,PIK3CA,PIK3CD,ACVR1C,PBK,TP53I3,ENPP1,PLCG1,PLK2,LIMK1,GNPTAB,NOD2,DHTKD1,ITPKA,GAB1,CDK17,NUAK1,TMEM55B,DGKQ,SOX9,NDUFA4,ISYNA1,TNFRSF19,MERTK,BMP2K,ATP5H,PPP4R1,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,NCAM1,MAST4,DGKG,MCCC2,GFPT1,PMPCB,MMD,ADCK3,STAT4,LPGAT1,CALM1,PIP4K2C,EPHA1,ELK1,SPTLC2,PSMA4,RASA1,STK17A,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,NRBP1,XDH,PLA2G4A,SPRED1,MTM1,DLGAP5,PAPSS2,INPP5D,RPS6KA1,TESK2,GRK6,PRKACA,DDR1,CDS1,CCND1,DOK4,DAB2IP,PDE4D,EPHB4,ACSL4,PHKA2,RASGEF1A,DLG3,SULT2B1,GPX4,SSH3,RIPK2,PTPN9,PANK1,PRKCQ,ATP1B1,PKMYT1,XRCC6BP1,EPHA10,IRS2,JAK1,CDK19,STK26,AXL,INPP4B,PNPLA6,SLC27A1,NRG1,MLKL,MAPK12,PKN1,PLPPR4,FGF19,PTEN,FAM20B,SGK3,SLC44A2,MAPK11,ERBB3,RASGRF1,SHMT1,PLSCR1,MPP1,RAPGEF2,PIK3R1,ELOVL3,GRIN1,AK4,YES1,FOS,GPLD1,FGFR2,ACVRL1,DBI,PPM1H,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,MELK,ACOT7,NMRK1,PPM1J,CAMKK1,EPHA4,PDGFB,CACNB4,SPTB,RPS6KA2,SHC3,IMPAD1,PAPSS1,PASK,SLC44A1,PAPL,DLG1,DUSP10,TECR,PTPRE,RASGRP1,PLK1,ROR1,PRKRA,IDH1,ADRBK2,STK17B,CDK1,PLCH1,NEIL1,AGPAT2,DOLPP1,CAB39,PIK3C2B,CPPED1,PRKAA2,LMTK3,RASA2,UBASH3B,CALM3,ADCK5,TEC,PHLPP1,IGF1R,MDFIC,PIM1,FAR2,PLCB2,MDFI,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,CDK5R1,MAPKAPK2,GNAS,NUDT16,PHLPP2,PLPP3,PRPS2,ALPK3,PLD1,JAK3,UGP2,IL15,PSME2,CTDSPL,ERBB2,LPIN3,PDGFA,PLCG2,PLK4,MINPP1,F2R,SCYL3,CTDSP2,SEPHS1,FRS3,MAP3K3,AKT1,PTPRU,FIGNL1,PTGER4,DUSP4,MAP3K6,ATP1A1,PTPRJ,ALDH5A1,ABHD12,PTK7,STK38,SPTBN5,ST3GAL1,PINK1,ENO2,CIT,GNE,PSMD10,TGFBR1,TRIB2,SBF1,PPP2R3A,ADRBK1,CDK16,ALPP,SGK1,BUB1,IQGAP3,SYK,PGM1,PSMB4,PLAUR,OGDHL,NADK2,RUNX3,MAPK8IP1,DGKE,PRDX4,SCG2,HIPK3 |
| 3.105e-09 | -19.59 | regulation of small GTPase mediated signal transduction | biological process | GO:0051056 | 281 | 62 | 16441 | 1675 |
ARHGAP11A,ARHGEF3,ARAP3,ADGRG1,FOXM1,TRIP10,ARHGEF11,RALBP1,RASA2,ARFGEF1,ERBB2,ARHGEF40,ARHGEF16,EPS8L2,ARHGEF10L,SIPA1L2,ITGA3,RALGPS2,ARHGEF37,KIF14,FAM13B,BCL6,DAB2IP,RASGEF1A,TIAM1,F2R,ALS2CL,SPRY2,RASGRP1,FARP2,RASGRF1,TIMP2,ARAP2,ARHGEF28,RHOA,SPATA13,STMN3,ARHGDIB,ICMT,ARHGEF26,ABR,RASA1,ARHGAP35,ARHGAP24,PLEKHG6,ARHGEF19,CSF1,SIPA1L1,MADD,PLEKHG1,FGD6,RHOBTB2,ARRB1,NRG1,ARF6,F2RL1,RAP1GAP,ABCA1,ARHGEF9,ARHGEF4,FGD1,ARFGEF3 |
| 3.117e-09 | -19.59 | skin | COSMIC cancer mutations | skin | 17124 | 1732 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.152e-09 | -19.58 | large_intestine | COSMIC cancer mutations | large_intestine | 17444 | 1751 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.403e-09 | -19.50 | response to wounding | biological process | GO:0009611 | 747 | 127 | 16441 | 1675 |
PLA2G4A,MYL9,CASP3,PAPSS2,INPP5D,TP53,ERBB2,F11R,ITPR2,CCNB1,VASH1,PRKACA,PDGFB,SDC1,DDR1,CALM2,PDGFA,WEE1,NOV,CYP1A1,CTGF,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,CDH3,EPB41L4B,LMAN1,F2R,RASGRP1,LAMP2,ENPP4,AKT1,KLK6,PRKAR2B,PRKCQ,ATP1B1,F12,CD40,ITPR3,MYL12A,ARF4,FZD7,OPTN,DPYSL3,MDK,PLCG1,KCNMB4,ARHGEF19,HPSE,ABHD12,PTK7,AXL,HDAC1,NRG1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,DGKQ,SDC4,HABP4,CALM3,KIF23,SELL,TGFBR1,SLC1A3,TEC,ETS1,MERTK,FBLN1,SIRPA,FZD6,ITGA3,CYR61,GATA2,FLRT3,CST3,CD9,PRKG1,BAX,ADAM15,ERBB3,WNT3A,DGKG,SYK,ATP2B1,ELK3,RHOA,PLSCR1,BCL9,PLAUR,CALM1,PIK3R1,ANO6,PPARA,C1GALT1C1,HMG20B,PDE5A,SCRIB,YES1,BCAR1,KIF11,GNA11,DGKE,RASGRP2,DGKH,GNAS,ARHGAP24,TIMP3,SERPINA1,SYT7,ACVRL1,PRCP,ITPR1,MATN2,ARRB1,ITGAV,ATP1B3,CENPE,HOXB13,L1CAM,EHD1,DOCK9 |
| 3.508e-09 | -19.47 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 110 | 33 | 17758 | 1761 |
ARHGAP11A,DLGAP5,ZNF395,DEPDC1,ATP8A1,C5orf30,KIF23,KCTD12,CCNB1,H1FX,ZFP36,KIF14,NEK2,BUB1,EGLN3,PLK1,HMMR,SUN2,CENPA,CD55,KIF20A,ASPM,CDC20,CR2,CDK5R1,H1F0,AURKA,NR4A2,CENPE,UBE2C,TRAF5,MAFF,EGLN1 |
| 3.584e-09 | -19.45 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 705 | 121 | 16491 | 1673 |
LTBP1,NMRK1,PAPSS2,CAMKK1,RPS6KA1,RET,EPHA4,TESK2,ERBB2,GRK6,CAMK1D,CCNB1,PRKACA,DDR1,CCND1,DAPK2,WEE1,RPS6KA2,PASK,PAPSS1,PIK3CA,PLK4,PIK3CD,EPHB4,PHKA2,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PANK1,PRKCQ,ROR1,PKMYT1,XRCC6BP1,MAP3K6,STK17B,CDK1,ADRBK2,EPHA10,JAK1,STK26,CDK19,PTK7,LIMK1,STK38,PLK2,AXL,PIK3C2B,MLKL,ITPKA,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,SOX9,GNE,DGKQ,ADCK5,TGFBR1,TEC,PKN1,TRIB2,MERTK,BMP2K,NRP2,IGF1R,ADRBK1,CDK16,FAM20B,DAPK1,MAP3K9,ADCK2,PRKG1,NEK2,SGK3,SGK1,MAPK11,BUB1,ERBB3,ALPK1,PIM1,PIKFYVE,DGKG,MAST4,SYK,MMD,TESK1,PIP4K2C,NADK2,STRADB,EIF2AK1,YES1,EPHA1,PDK3,PDIK1L,DGKE,CDK5R1,STK17A,DGKH,MAPKAPK2,PRKAG2,FGFR2,ACVRL1,CSNK1G1,RYK,ALPK3,AURKA,PGM2L1,STK39,CDK18,LRRK1,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 3.645e-09 | -19.43 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16661 | 1699 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.734e-09 | -19.41 | cell migration | biological process | GO:0016477 | 771 | 130 | 16441 | 1675 |
RET,EPHA4,HEXB,F11R,PDGFB,DNER,SDC1,SH3KBP1,CTGF,ELMO2,MITF,PIK3CA,PIK3CD,CTTN,SEMA3G,TIAM1,CYP1B1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,MDK,PLCG1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,S100A2,MERTK,TNS3,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PRKG1,TNFRSF12A,ZRANB1,NUP85,CCDC88A,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,ATP1B3,NDE1,SHROOM2,SEMA3A,JAK3,INPP5D,EMP2,APC2,DDR1,ARHGEF16,NOV,ARTN,LHX6,DIXDC1,TWIST1,DAB2IP,EPHB4,PDE4D,RASGEF1A,TSPAN1,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,JAK1,CORO1C,AXL,PTK7,PEX2,NRG1,CTHRC1,ADGRG1,CD63,SDC4,EPS8,SELL,TGFBR1,PKN1,EFNB1,FGF19,SIX4,SIRPA,SGPL1,CXCL16,PTEN,FUT8,KIAA0319,BAX,SYK,GCNT1,PARP9,HES1,RHOA,NR4A1,ASPM,RAPGEF2,PIK3R1,YES1,BCAR1,GPLD1,PITX2,ARHGAP24,SCG2,ACVRL1,ITGAV,SOX8,ARSB,L1CAM |
| 3.757e-09 | -19.40 | regulation of localization | biological process | GO:0032879 | 2322 | 318 | 16441 | 1675 |
LAMP1,ACACB,TXN,LGR4,ATP8A1,RET,CACNA2D2,IL18,PLXNA1,SYTL4,CAMK1D,CCNB1,VASH1,BARD1,NCS1,CALM2,DAPK2,STIM1,CABP1,KCNS3,CRY2,TACSTD2,SEMA3G,PIK3CD,TMEM37,PACSIN1,ACVR1C,NBPF3,PRKAR2B,SLC25A5,ABR,ENPP1,PLCG1,SLC25A4,DNM1L,NKD1,FAM110C,NOD2,SARAF,ARF6,HSPB1,F2RL1,GAB1,DDX58,SEMA6B,SCN5A,NFKBIE,TBC1D1,HLA-E,SOX9,RAB23,SLC25A27,MERTK,LMNA,ITGA3,CYR61,RIMS3,MEGF8,NEK2,DAPK1,SORL1,CACNA1D,SYTL3,NUP85,RIMS2,EPB41L5,KCNJ12,MMD,CALM1,ANO6,ERO1A,EPHA1,TP53INP2,PLIN5,STX3,AP1AR,PRKAG2,SEMA4D,ITPR1,STK39,CFAP20,NUP58,TMEM173,EHD1,THRA,IQGAP1,PKP2,BCL2L1,CD274,PRKACA,APC2,NOV,CDH1,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,ACSL4,TSPAN1,RAB27B,MYT1,SCN3A,SEMA3B,DOCK4,SYNE2,UTRN,PRKCQ,ATP1B1,ITPR3,SNX12,FZD7,IRS2,PPP2R5A,CORO1C,WFS1,AXL,INPP4B,NRG1,TCAF1,NKX3-1,SDC4,ANO9,PKN1,ETS1,SRPX2,FGF19,SIX4,WWP2,NEO1,SNTA1,CXCL16,GNB5,PTEN,FAM20B,SGK3,BAX,ADAM15,TMBIM6,MAPK11,ERBB3,CITED2,TPCN1,RASGRF1,MPP1,RAPGEF2,PIK3R1,GRIN1,FURIN,GPLD1,NUCB1,SYT7,ACVRL1,NR4A3,ITGAV,GPER1,FHL1,FZD5,ARSB,EXPH5,ILDR1,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,SLC8B1,SDC1,ZFYVE16,EPCAM,NKAIN3,RAB15,DPYSL2,SIVA1,PASK,ABCA2,DLG1,TRPC1,RAB20,MYRIP,RASGRP1,CYP1B1,KCNIP3,TRIM8,CELSR2,EZR,ARHGDIB,CDK1,DPYSL3,TRIM9,KCNMB4,RAB11FIP1,CAB39,RAP1GAP,PRSS8,BMF,ARAP3,LGALS3,SERPINE2,BVES,UBASH3B,FXYD3,CALM3,NCKAP1,FBLN1,ANO1,IL18R1,IGF1R,CA2,GATA2,KCNN4,FXYD5,MDFIC,WNT3A,MDFI,SPATA13,CDK5R1,GNAS,ONECUT1,PLPP3,CSF1,TMEM30A,CDCA5,NFKBIA,YOD1,EGFL7,ATP1B3,PLD1,JAK3,SEMA3A,PROM2,LZTFL1,SORBS1,NF2,TP53,ERBB2,COL18A1,EMP2,BCAP31,ARHGEF16,SYTL2,IER3,PDGFA,SVBP,KIF14,REEP1,PLCG2,BCL6,CDH3,TWIST1,EPB41L4B,SCN2A,F2R,CHP1,PPIF,SIRT1,CLCN3,ERLEC1,AKT1,PTPRU,CCSAP,PTGER4,CD40,DOCK5,DAG1,ATP1A1,PTPRJ,EFNA5,SYT13,ABCA1,BIN1,ANXA3,PACSIN2,PINK1,CD63,ADGRG1,PSMD10,SELL,TGFBR1,HMGN3,PPP2R3A,NRP2,HDAC9,KIF5B,CARD8,ADRBK1,ADORA1,CDK16,LLGL2,BMP7,UBE2J1,SGK1,TSPAN13,SYK,MYO5A,HES1,SUN2,RHOA,RAB3B,SYBU,LITAF,RGCC,PPARA,BORA,BBS2,BCAR1,BANK1,SWAP70,PRCP,SPINT2,RAP2C,NETO2,ARRB1,SPCS3,NDFIP1,TBC1D4,PKIA,ABCG1 |
| 4.135e-09 | -19.30 | positive regulation of response to stimulus | biological process | GO:0048584 | 1946 | 274 | 16441 | 1675 |
LAMP1,TXN,LGR4,RET,NRG2,PSME1,IL18,CAMK1D,SLC20A1,CARD10,GRM5,CALM2,DAPK2,PSMD1,CTGF,ELMO2,IL31RA,PIK3CA,PIK3CD,TNIP1,SH3BGRL,F12,POR,PLCG1,DNM1L,ANKRD6,PLK2,LIMK1,NKD1,FAM110C,NOD2,TMOD2,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,DDX58,CDKN1C,SCOC,THEMIS2,HLA-E,SOX9,TNFRSF19,KIAA1161,TFAP4,CYR61,PIK3AP1,MEGF8,MAP3K9,TNFRSF12A,MYDGF,NCAM1,SOCS5,KLK5,MICB,CALM1,AMER1,ANO6,PIP4K2C,ELK1,PSMA4,STX3,RASA1,FAS,SEMA4D,PELI2,ITPR1,KLK7,GDF11,ARPC2,MAP3K5,CFAP20,IFIH1,TMEM173,RUSC1,XDH,SPRED1,INPP5D,RPS6KA1,BCL2L1,PRKACA,NOV,ST5,RNF220,DACT1,DAB2IP,PDE4D,RASGEF1A,LGMN,NR2C1,ENPP4,RIPK2,FZD4,PRKCQ,ITPR3,FZD7,IRS2,JAK1,CDK19,AXL,NRG1,NKX3-1,EPS8,BTN3A1,PDIA3,PKN1,FGF19,HLA-A,NEO1,CTSC,PTEN,BAX,PLEKHF1,SLC44A2,MAPK11,ERBB3,CITED2,CNPY3,SPRY2,TRIM62,RASGRF1,PLSCR1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,CNTNAP1,FGFR2,ACVRL1,NR4A3,RYK,GRIN2D,GPER1,LRRK1,HMGA1,FZD5,EPHA4,LMCD1,ARFGEF1,NENF,ITPR2,HDAC6,ERP29,PDGFB,CACNB4,SPTB,RPS6KA2,SHC3,NPNT,IL6ST,TSPAN6,SIVA1,AKR1B1,SLC39A10,SCARA3,S100A13,RASGRP1,SMAGP,CYP1B1,CD55,TRIM8,ITCH,CR2,KLK6,PRKRA,CDK1,RHEB,KDM4D,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,RRAGD,PRKAA2,LASP1,BMF,RASA2,CALM3,NCKAP1,TEC,ANO1,IL18R1,IGF1R,KCNN4,MDFIC,C10orf54,WNT3A,ZRANB1,MDFI,PDE5A,MAPKAPK2,GNAS,NUDT16,PVRL2,CSF1,PLPP3,NFKBIA,NLRC5,JAK3,TOB1,RNF146,AVPI1,SORBS1,IL15,FOXM1,PSME2,TP53,ERBB2,IL27RA,EMP2,BCAP31,PDGFA,ARTN,PLCG2,CDH3,DIXDC1,F2R,DVL2,CTH,SULF2,FRS3,PPIF,SIRT1,MAP3K3,TIMP2,AKT1,S100A4,PTGER4,CD40,DUSP4,MAP3K6,PTPRJ,SECTM1,IRF7,SPTBN5,PINK1,TSPAN15,ADGRG1,CD63,PSMD10,SELL,GDF15,TGFBR1,PPP2R3A,ADORA1,BMP7,BUB1,IQGAP3,SYK,HES1,RHOA,PSMB4,PLAUR,ASPM,RC3H2,RGCC,LITAF,BCAR1,MAPK8IP1,CTSL,HLA-B,SWAP70,BANK1,SCG2,TWSG1,ARRB1,NDFIP1,L1CAM |
| 4.157e-09 | -19.30 | cell communication | biological process | GO:0007154 | 5288 | 645 | 16441 | 1675 |
ADD1,IL15RA,DNAJC3,RET,NRG2,IL18,SYTL4,CA8,CARD10,GRM5,CALM2,DAPK2,PSMD1,CLDN4,CRY2,PIK3CD,SEMA3G,TIAM1,TIPARP,TNIP1,CDA,TFAP2C,PRKAR2B,ARF4,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NUAK1,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ATG4A,TFAP4,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,NCAM1,DGKG,NUP85,PAQR7,SALL4,STAT4,ERO1A,NPHP3,ELK1,PSMA4,GNA11,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,STK39,GDF11,NDE1,ARPC2,NUP58,DOCK9,ARHGAP11A,NQO1,CD82,INPP5D,PKP2,IL13RA1,NUF2,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,ENPP5,RTKN2,ARL4D,DLG3,RASGEF1A,RAB27B,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,IRS2,SLC9A6,CORO1C,WFS1,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TNRC6C,NKX3-1,SDC4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,SGPL1,CTNNBIP1,DIRAS3,ITGB8,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,AMOTL2,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,CNTNAP1,ACVRL1,NR1D2,SYT7,RAB11FIP2,NR4A3,CENPE,ITGAV,USF2,WDR45B,MYL9,SIGIRR,BCAM,EPAS1,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,SHC3,IL6ST,MITF,DUSP10,NTN4,SCARA3,THRB,PLK1,KCNIP3,MCTP1,CELSR2,CR2,EZR,ARFRP1,RHEB,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,NCKAP1,RAB6A,CNTNAP2,FBLN1,DHRS3,ANO1,IL18R1,IGF1R,KIF13B,FRAS1,SELK,MDFIC,PIM1,WNT3A,PLCB2,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,TCF7,SCRIB,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,NF2,FOXM1,TP53,ERBB2,CCDC68,STIL,BCAP31,SYTL2,IER3,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,CTH,SULF2,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,PTK7,STK38,IRF7,EFNA5,ANXA9,SYT13,ZMAT1,PINK1,CPEB4,ADGRG1,DAP,CDCA8,GABRG2,PSMD10,GDF15,CRABP2,AIP,FZD6,PPP2R3A,DNAJB9,NRP2,M6PR,CDK16,SGK1,TRIM21,BUB1,TSPAN13,SYK,DLGAP1,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,FAT4,SCG2,TWSG1,NMI,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,TXN,LGR4,HSPG2,PSME1,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,ATRNL1,IRF2,TACSTD2,RCAN3,METAP2,ACVR1C,CASP9,AGO4,SAV1,ZFAND5,PLK2,NKD1,EIF4EBP2,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,SLC1A3,TNFRSF19,TSPAN7,MESDC2,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,PRKG1,OPN3,DAPK1,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,MICB,CALM1,ANO6,AMER1,EPHA1,ANTXR1,STX3,RASA1,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,CABIN1,NR4A2,MAP3K5,IFIH1,SPRED1,REPS2,TCTN2,S100A11,TRIP10,RALBP1,THRA,IQGAP1,RPS6KA1,BCL2L1,CD274,DDR1,EPS8L2,ZFYVE9,APLP2,NOV,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,LGMN,MED30,NR2C1,ATG4D,SEMA3B,DOCK4,PRKCQ,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,FZD7,EPHA10,JAK1,PPP2R5A,NGFRAP1,STK26,TSPAN18,SLC27A1,NRG1,NR3C2,ARHGEF3,DEPDC1,IGFBP6,CENPI,EPS8,ARL4C,HERC5,EFNB1,FGF19,LGALS3BP,ADGRB2,HLA-A,TEAD3,RASSF8,E2F7,GNB5,PTEN,FJX1,FUT8,CD9,SGK3,SLC44A2,ERBB3,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ALDH2,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,FGFR2,RYK,GRIN2D,GPER1,LRRK1,FZD5,MELK,RGMA,LTBP1,CASP3,CAMKK1,DNER,CACNB4,TRIM68,KREMEN1,PTCHD4,SH3KBP1,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,DPYSL2,SIVA1,TSPAN6,DLG1,AKR1B1,RAB20,CTTN,MYH14,PTPRE,RASGRP1,CYP1B1,TRIM8,CENPA,USP18,ITCH,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,MDK,CXXC4,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,NRGN,RAP1GAP,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,ETV5,ASB9,CALM3,TEC,PHLPP1,CA2,KCNN4,DIAPH2-AS1,HLA-C,C10orf54,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,BCAR3,GNAS,ONECUT1,PLPP3,NFKBIA,RHOBTB2,YOD1,JAK3,COL16A1,RARG,TOB1,GAS2L1,SORBS1,SPC25,IL15,PSME2,PDIA5,MRAS,IL27RA,ARHGEF16,SS18,ARTN,KIF14,GOT1,DIXDC1,F2R,PDIA6,CHP1,FRS3,MAP3K3,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CASP4,MAP3K6,SOCS3,ARHGAP35,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LIFR,SORT1,ARHGEF11,CIT,LRP4,AES,TGFBR1,NOTUM,HMGXB4,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,IQGAP3,MYO5A,SYPL1,RAB3B,DEPDC4,NR4A1,FOXL1,LEPR,CTSL,ARHGAP24,HLA-B,RND3,CTSV,RAP2C,DTX4,ARRB1,UACA,GEM,SOX8,AHR,L1CAM,CD33,SNPH |
| 4.243e-09 | -19.28 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14963 | 1560 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,ZNF365,MYT1,SNX10,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,AK4,CNTNAP1,PLOD2,RAB11FIP2,SYT7,DBI,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,SYTL2,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,LBR,PARM1,H1FX,NRP2,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,TFAP2A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,ACAP2,TRANK1,EPHB4,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,ABCG1,CD33,ACACB,KLK10,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,RELL1,GAB1,E2F8,FAM169A,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,HMGA1,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,H1F0,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,FADS2,B3GNT7,MFI2,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,CPEB2,JARID2,ESYT2,EXPH5,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,GRHL1,ZCCHC12,DPYSL2,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,UTP14C,NFKBIA,ALPK3,RHOBTB2,YOD1,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 4.309e-09 | -19.26 | cell part morphogenesis | biological process | GO:0032990 | 967 | 155 | 16441 | 1675 |
MYL9,EMX1,UGT8,AK7,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,LRRC6,SHC3,DPYSL2,DLG1,TRPC1,NTN4,MYH14,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,EZR,DPYSL3,DZIP1L,PLCG1,MAP2,DNM1L,LIMK1,TRAF3IP1,UNC5B,MYL12B,SCN5A,RASA2,RAB23,CALM3,IGF1R,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,DPYSL5,RGMB,CALM1,EPHA1,NPHP3,RANBP9,PSMA4,NFIB,RASA1,CDK5R1,ONECUT1,PVRL2,SEMA4D,MATN2,AURKA,PITPNA,NR4A2,ARPC2,CFAP20,JAK3,SEMA3A,KLF7,EHD1,SPRED1,MTM1,TCTN2,PSME2,RPS6KA1,IQGAP1,C5orf30,ERBB2,BCL2L1,STIL,PDGFA,TTC21B,ARTN,DACT1,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,SNX10,FRS3,SEMA3B,COL6A2,PRKCQ,SLC11A2,ALCAM,DAG1,MYL12A,CEP162,ARHGAP35,EPHA10,IRS2,JAK1,SLC9A6,NRG1,EFNA5,SPTBN5,LIFR,COBL,TTC8,COL9A3,PACSIN2,ARHGEF11,POC1B,LRP4,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,NEO1,KIF5B,PTEN,BMP7,BAX,SGK1,ERBB3,S100A6,FARP2,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,CFAP46,FMN1,RAPGEF2,GRIN1,YES1,BBS2,CNTNAP1,FGFR2,NR4A3,RYK,PGRMC1,GRIN2D,ITGAV,CEP41,L1CAM,RGMA |
| 4.323e-09 | -19.26 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | 100 | 31 | 17758 | 1761 |
SHMT1,S100A11,CAST,AMFR,STAT4,ARL4C,KIF1C,CR2,SLC1A3,RAB6A,NUCB2,STK17B,RABGGTA,ENDOD1,PGF,NCOA3,STIM1,TSPAN6,SLC16A6,STK38,PPP4R1,ALDH1A3,PCYOX1,FUT1,PITPNA,ADIPOR1,WWP1,IGFBP2,TIAM1,NRBP1,GM2A |
| 4.626e-09 | -19.19 | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | 206 | 49 | 17758 | 1761 |
SLC25A24,MRC2,LGALS3,ST14,ATP8A1,FXYD3,ESRP1,SOX9,HDAC11,HAL,SDC1,PHLDA1,SRPX2,ANO1,EPDR1,EPCAM,MLPH,CDH1,GRHL1,CYR61,ELF5,TMEM51,TNFRSF12A,IGFBP2,TACSTD2,RAB27B,SLC12A2,GM2A,NFE2L3,FADS2,TGIF1,CD55,SLC39A8,TFAP2C,CDK1,MAPK8IP1,EDNRA,GABARAPL1,SOX13,CARHSP1,ETS2,SHROOM3,NGFRAP1,PLK2,BMP1,LRRK1,COL16A1,GAB1,PROM2 |
| 4.847e-09 | -19.15 | signal transduction | biological process | GO:0007165 | 4816 | 594 | 16441 | 1675 |
ADD1,IL15RA,DNAJC3,RET,NRG2,IL18,CA8,CARD10,GRM5,CALM2,DAPK2,PSMD1,CLDN4,CRY2,PIK3CD,SEMA3G,TIAM1,TIPARP,TNIP1,CDA,PRKAR2B,ARF4,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,ITPKA,ARF6,HSPB1,GAB1,NUAK1,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,TFAP4,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,NCAM1,DGKG,NUP85,PAQR7,SALL4,STAT4,ERO1A,NPHP3,ELK1,GNA11,PSMA4,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,STK39,GDF11,NDE1,ARPC2,NUP58,DOCK9,ARHGAP11A,CD82,INPP5D,IL13RA1,NUF2,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,RTKN2,ARL4D,RASGEF1A,RAB27B,MX1,SEC61B,RIPK2,FZD4,RAB38,IRS2,SLC9A6,WFS1,CORO1C,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,NKX3-1,TNRC6C,SDC4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,SGPL1,CTNNBIP1,DIRAS3,ITGB8,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,AMOTL2,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,CNTNAP1,NR1D2,ACVRL1,NR4A3,CENPE,ITGAV,MYL9,SIGIRR,BCAM,EPAS1,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,SHC3,IL6ST,MITF,DUSP10,SCARA3,THRB,PLK1,KCNIP3,MCTP1,CELSR2,CR2,EZR,ARFRP1,RHEB,OPTN,PLCH1,WIPI1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,NCKAP1,RAB6A,FBLN1,DHRS3,ANO1,IL18R1,IGF1R,KIF13B,SELK,MDFIC,PIM1,WNT3A,PLCB2,DPYSL5,RGMB,CORO2A,STRADB,TCF7,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,CSF1,ITGA7,LTBP2,PLD1,SEMA3A,IFI6,RNF146,NF2,FOXM1,TP53,ERBB2,CCDC68,STIL,BCAP31,IER3,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,SULF2,CTH,SIRT1,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,IRF7,EFNA5,ZMAT1,PINK1,CPEB4,ADGRG1,DAP,CDCA8,PSMD10,GABRG2,GDF15,CRABP2,AIP,FZD6,PPP2R3A,DNAJB9,NRP2,M6PR,SGK1,TRIM21,BUB1,TSPAN13,SYK,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,FAT4,SCG2,TWSG1,NMI,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,TXN,LGR4,HSPG2,PSME1,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,CTGF,ELMO2,IL31RA,PIK3CA,ATRNL1,IRF2,TACSTD2,RCAN3,METAP2,ACVR1C,CASP9,AGO4,SAV1,ZFAND5,PLK2,NKD1,EIF4EBP2,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,TNFRSF19,TSPAN7,MESDC2,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,PRKG1,OPN3,DAPK1,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,GPR161,RIMS2,SOCS5,GFPT1,PRODH,MICB,ANO6,AMER1,CALM1,EPHA1,ANTXR1,RASA1,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,PELI2,NR4A2,CABIN1,MAP3K5,IFIH1,SPRED1,TCTN2,REPS2,S100A11,TRIP10,IQGAP1,RPS6KA1,THRA,RALBP1,CD274,BCL2L1,DDR1,ZFYVE9,EPS8L2,APLP2,NOV,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,LGMN,NR2C1,MED30,SEMA3B,DOCK4,PRKCQ,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,FZD7,EPHA10,JAK1,PPP2R5A,STK26,NGFRAP1,TSPAN18,SLC27A1,NRG1,NR3C2,ARHGEF3,DEPDC1,IGFBP6,CENPI,EPS8,ARL4C,HERC5,EFNB1,FGF19,LGALS3BP,ADGRB2,HLA-A,TEAD3,RASSF8,E2F7,GNB5,PTEN,FUT8,SGK3,CD9,SLC44A2,ERBB3,CITED2,CNPY3,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,FGFR2,RYK,GRIN2D,GPER1,LRRK1,FZD5,MELK,RGMA,LTBP1,CASP3,DNER,CACNB4,TRIM68,KREMEN1,PTCHD4,SH3KBP1,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,DPYSL2,SIVA1,TSPAN6,AKR1B1,RAB20,CTTN,MYH14,PTPRE,RASGRP1,CYP1B1,TRIM8,CENPA,USP18,ITCH,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,MDK,CXXC4,GPRC5B,MADD,CAB39,ADIPOR1,NRGN,RAP1GAP,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,ASB9,CALM3,TEC,PHLPP1,CA2,DIAPH2-AS1,HLA-C,C10orf54,ZRANB1,CCDC88A,MDFI,ELK3,PDE5A,BCAR3,GNAS,ONECUT1,PLPP3,NFKBIA,RHOBTB2,YOD1,JAK3,COL16A1,RARG,TOB1,SORBS1,SPC25,IL15,PSME2,PDIA5,MRAS,IL27RA,ARHGEF16,SS18,ARTN,KIF14,GOT1,DIXDC1,F2R,PDIA6,CHP1,FRS3,MAP3K3,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CASP4,MAP3K6,SOCS3,ARHGAP35,SECTM1,TLE1,SPTBN5,ABCA1,LIFR,SORT1,ARHGEF11,CIT,LRP4,AES,TGFBR1,NOTUM,HMGXB4,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,IQGAP3,RAB3B,DEPDC4,NR4A1,LEPR,CTSL,ARHGAP24,HLA-B,RND3,RAP2C,DTX4,ARRB1,UACA,GEM,SOX8,AHR,L1CAM,CD33 |
| 4.859e-09 | -19.14 | MODULE_342 | MSigDB lists | MODULE_342 | 200 | 48 | 17758 | 1761 |
MYL9,PRSS8,FBLIM1,SORBS1,LMTK3,TSC22D3,FXYD3,CCDC68,F11R,CRABP2,AIFM2,SDC1,LGALS3BP,CYP26A1,EPS8L2,SH2D4A,ELF3,EPCAM,SCNN1A,MLPH,CDH1,CDH3,CLDN4,IGFBP2,TACSTD2,EGLN3,SSH3,PRSS23,VWA1,GRTP1,PPP1R14C,PTGFRN,TP53I3,CYB5A,GALNT3,PTPRF,GPRC5B,CDCA5,SPINT2,FAM83D,SERPINB6,ANXA9,MAL2,HOOK1,F2RL1,E2F8,OCLN,XDH |
| 5.068e-09 | -19.10 | Prot_kinase_dom | interpro domains | IPR000719 | 482 | 89 | 18293 | 1814 |
CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,CAMK1D,GRK6,DDR1,PRKACA,DAPK2,WEE1,RPS6KA2,PASK,PLK4,EPHB4,SCYL3,MAP3K3,PLK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,CDK1,EPHA10,JAK1,STK26,CDK19,PLK2,PTK7,STK38,LIMK1,AXL,MLKL,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,TGFBR1,TEC,TRIB2,PKN1,MERTK,BMP2K,ADRBK1,IGF1R,CDK16,SGK3,NEK2,MAP3K9,PRKG1,DAPK1,SGK1,MAPK11,BUB1,ERBB3,PIM1,MAST4,SYK,TESK1,STRADB,EIF2AK1,YES1,EPHA1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,CSNK1G1,RYK,AURKA,STK39,CDK18,LRRK1,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 5.326e-09 | -19.05 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16536 | 1689 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,AIP,LBR,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,GEM,L1CAM,SNPH |
| 5.562e-09 | -19.01 | atypical | COSMIC cancer mutations | atypical | 529 | 95 | 17775 | 1757 |
NF2,VANGL1,RPS6KA1,CAMKK1,EPHA4,RET,TP53,TESK2,ERBB2,GRK6,CAMK1D,LPIN3,PRKACA,DDR1,CDKN2C,DAPK2,WEE1,RPS6KA2,FAM46A,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,IDH1,ADRBK2,STK17B,MAP3K6,EPHA10,JAK1,CDK19,PLK2,PTK7,LIMK1,STK38,AXL,HDAC1,MLKL,PPP2R2D,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,PRKG1,MAP3K9,ADCK2,SGK3,SGK1,BUB1,MAPK11,ALPK1,PIM1,ERBB3,SYK,TESK1,ADCK3,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,P4HA3,AURKA,UACA,ALPK3,CDK18,MAP3K5,JAK3,NRBP1,HIPK3,MELK |
| 6.058e-09 | -18.92 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | 195 | 47 | 17758 | 1761 |
GRN,SORT1,AVPI1,PAPSS2,LGR4,CD63,ST14,TBC1D1,GALNT12,BLVRB,PPFIBP2,TGFBR1,CTSZ,CRABP2,SLC20A1,MERTK,BCAP31,SIRPA,LMNA,ARHGEF10L,APLP2,TNS3,CA2,CTSC,CD9,TMEM51,VAT1,AHCY,SYK,NAGA,CYP1B1,LAMP2,PDGFC,TIMP2,RIPK2,NPC2,IDH1,LHFPL2,TP53I3,FUCA1,RBM47,SLC2A6,CTSA,GLA,SLC27A3,ACOT7,CD33 |
| 6.238e-09 | -18.89 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16526 | 1688 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,GEM,L1CAM,SNPH |
| 6.428e-09 | -18.86 | negative regulation of signaling | biological process | GO:0023057 | 1132 | 175 | 16441 | 1675 |
SIGIRR,LTBP1,LGR4,NDRG2,PSME1,SYTL4,GRM5,SH3KBP1,PSMD1,IL6ST,RGS3,TSPAN6,DLG1,DUSP10,CRY2,CTTN,PTPRE,TNIP1,ACVR1C,ITCH,PBK,SLC35C1,EZR,SLC25A5,OPTN,CXXC4,ENPP1,ANKRD6,PLK2,TRAF3IP1,MADD,NKD1,RAB11FIP1,NOD2,PRKCDBP,HDAC1,UNC5B,HSPB1,F2RL1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,RASA2,UBASH3B,SOX9,PHLPP1,FBLN1,DHRS3,LMNA,MECOM,ITGA3,IGF1R,PIK3AP1,GATA2,VASN,DAPK1,SORL1,WNT3A,GPR161,MDFI,SOCS5,CYP26B1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,G2E3,PLIN5,RASA1,AP1AR,ONECUT1,NFKBIA,ITPR1,SH3BP4,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,SPRED1,NF2,FOXM1,NLRX1,INPP5D,DDIT4L,PSME2,RGS20,TP53,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,IER3,CCND1,NOV,DACT1,BCL6,DAB2IP,TWIST1,LGMN,CDKN2D,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,PRKCQ,ERBB2IP,DUSP4,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,WFS1,TRABD2A,TLE1,NRG1,RGS14,CTHRC1,GCLM,PINK1,NKX3-1,LRP4,PSMD10,TGFBR1,AES,NOTUM,GSTP1,PPP2R3A,FZD6,HMGXB4,CD109,CTNNBIP1,CARD8,ADRBK1,ADORA1,PTEN,BMP7,BAX,TMBIM6,ERBB3,FAIM,SPRY2,TGIF1,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,PELI3,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 6.593e-09 | -18.84 | brain | COSMIC cancer mutations | brain | 17017 | 1724 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.652e-09 | -18.83 | CHANG_CYCLING_GENES | MSigDB lists | CHANG_CYCLING_GENES | 141 | 38 | 17758 | 1761 |
CASP3,DLGAP5,HJURP,DEPDC1,FOXM1,CKAP2,PTTG1,CDCA8,KIF23,NUF2,SDC1,BARD1,SCML1,TOP2A,UBE2T,BUB1,IFIT1,CKS2,HMMR,PLK1,CENPA,PBK,NUSAP1,ANLN,CCNF,CDK1,G2E3,PRIM1,ANKRD10,FAM64A,PRPS2,CDCA5,FAM83D,AURKA,DONSON,UBE2C,CCNB2,MELK |
| 6.960e-09 | -18.78 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6650 | 768 | 17775 | 1757 |
ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,AK7,SLC25A13,RET,CACNA2D2,ISOC2,CA8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,DAPK2,WEE1,MUC4,CYP2S1,TUBG1,ACOX2,PIK3CD,RNF26,TIAM1,MGAT5,APOBEC3G,NWD1,SMARCA2,TNIP1,SH3BGRL,MTRF1L,PRKAR2B,LOXL2,F12,CYP4F3,COL12A1,ABR,PIAS3,ENPP1,CARHSP1,MID1IP1,ATP7B,LIMK1,AGFG2,SERPINB6,RELL1,E2F8,NXT2,ITGA6,MTL5,SLC36A4,GPSM2,MERTK,TTYH3,LMNA,ELF3,RABGGTA,GNS,FRY,MEGF8,RIMS3,FAM13B,NEK2,MAP3K9,CADPS2,ALPK1,ZMYM1,NCAM1,MYLIP,ULBP2,DGKG,PPP6R1,C9orf72,HPS3,SLC37A1,SALL4,MYBL2,NPHP3,SPTLC2,STK17A,PTPRF,CACHD1,NCOA3,SLC4A4,SEMA4D,SETD3,ITPR1,CLMN,AURKA,MDH1,TMEM159,ARPC2,ZNF502,TMEM173,ADAMTS16,DOCK9,ARHGAP11A,PAPSS2,ACTR8,PKP2,TESK2,PRSS22,GRK6,PRKACA,APC2,REPS1,ZNF385B,APPBP2,MUC16,ST5,SCNN1A,CDH1,SNX10,MYT1,TMEM9,SCN3A,TMEM200B,ENPP4,MX1,COL6A2,RIPK2,FZD4,SEPT6,PLEKHO1,SYNE2,NUSAP1,RAB38,SNX12,SHROOM3,CDK19,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,RGS14,MAPK12,TTC8,CKAP2,SDC4,OSGIN2,ANO9,PKN1,PLPPR4,GSTP1,ETS1,SRPX2,TIPRL,HOXB2,NEO1,PDIA4,ADD3,FUT2,ANKS1B,CTSC,FAM102A,TMBIM6,ECI2,WWP1,MAPK11,TPCN1,CRTAP,AMOTL2,ADAMTS2,RAPGEF2,PIK3R1,MRS2,NUB1,SNTB1,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,ACVRL1,NR1D2,CENPE,ITGAV,HMGA1,OSR1,CYBRD1,ACOT7,TLL2,TMEM131,MYL9,SIGIRR,BCAM,KIAA1462,TRIM2,EPAS1,EPHA4,FHDC1,NDC80,TEX2,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,IL6ST,ABCA2,TLN2,MYBL1,DDX59,NEB,CCDC38,ZNF462,PLK1,KCNIP3,CELSR2,STAU2,CBX6,EZR,CR2,ARFRP1,ANLN,LHFPL2,ZBTB7B,RHEB,DZIP1L,OPTN,TRIM9,HS6ST1,MSL1,WIPI1,P4HA2,HOXA9,RAB11FIP1,ARRDC1,PIK3C2B,PIEZO1,EPB41L4A,MYL12B,RMND5A,PRSS8,PRKAA2,RUNX2,HJURP,LGALS3,PDCL,ADCK5,CNTNAP2,NCKAP1,C3orf18,DHRS3,ANO1,B4GALNT1,TNS3,IGF1R,KIF13B,EXOC8,AHCY,PIM1,FAR2,PLCB2,ALDH3A2,ABCC1,CHSY3,PCDH1,PLEKHA6,TESK1,PCBP3,CORO2A,ZNF320,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,IFIT3,G2E3,CDK5R1,FOXD2,MAPKAPK2,PRPS2,SLC2A6,ZDHHC7,LTBP2,PLD1,ZDBF2,SEMA3A,NF2,HOXB7,UPF3B,CTDSPL,XYLT1,TP53,ERBB2,SLC7A2,FAM198B,CYP26A1,SYTL2,ATP6V0B,WDR44,EFR3A,PLCG2,PLK4,GLB1L2,ESPN,NOTCH3,SCN2A,CTH,SULF2,CLCN3,TMTC1,MBP,ERLEC1,AKT1,CDC20,ACO1,DAG1,ATP13A2,DNAJC10,DUOX1,ATP1A1,IDE,PRRT4,PTPRJ,PTK7,STK38,ADAMTS14,SYT13,NDST3,CMTM4,BIN1,CMAS,COL9A3,PINK1,GOLIM4,CDH22,CPEB4,RUSC2,CDCA8,SELL,HMGN3,LBR,PARM1,PPP2R3A,DNAJB9,CD109,FOXP2,ALPP,CDK16,TFAP2A,SGK1,BUB1,FAIM,SYK,ATP2B1,IGDCC4,NFE2L3,DLGAP1,FBLN5,PSMB4,IFITM3,NR3C1,AMFR,PRICKLE1,MAML2,COL7A1,BBS2,BCAR1,MAPK8IP1,DGKE,BSDC1,SCRN2,FUCA1,SERPINA1,FAT4,NAT1,TMC5,NETO2,PGRMC1,NDFIP1,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,TXN,PPP4R4,TTC39B,HSPG2,LGR4,VANGL1,PPFIBP2,TAP1,PLXNA1,NANS,CAMK1D,SLC20A1,SLC9A7,ANKS6,CTGF,ZNF823,STIM1,ZFP36,RGS3,IQCE,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,ATRNL1,IRF2,MARCH2,METAP2,LAMP2,LOC81691,KIFC2,ACVR1C,PBK,CASP9,NBPF3,KIF13A,TNS1,GALNT7,SAV1,SLC25A5,POR,AHRR,ANKRD10,RBM47,GDE1,PLK2,GNPTAB,NKD1,LRIG1,FAM110C,DHTKD1,TANC2,WBSCR27,UNC5B,LZTS1,DDX58,MRC2,MRPL44,CDK17,HLA-E,C6orf106,TNFRSF19,BMP2K,MESDC2,C9orf69,DOPEY2,ITGA3,BHLHE41,SLC16A6,VASN,AIM1,DAPK1,ADCK2,TPST1,PRKG1,TMEM51,SORL1,CACNA1D,TRAK2,IGSF3,GFPT1,PMPCB,KCNJ12,PRODH,KLK5,PRSS23,TBC1D8B,ADCK3,MICB,CALM1,AMER1,ANO6,NPC2,ATP8B3,ANTXR1,NFIB,FRMD4B,MMP15,DGKH,GABRD,SLCO4A1,PLEKHH2,DCK,MATN2,TCEAL4,FAM83D,AGBL5,FGD6,SFMBT1,CABIN1,CDK18,PER3,PLIN3,MAP3K5,IFIH1,NRBP1,FRMPD3,SLC2A4,DLGAP5,TRIP10,ST14,NLRX1,IQGAP1,RALBP1,RPS6KA1,CCDC110,BCL2L1,TMEM170B,CD274,DDR1,AIFM2,ZFYVE9,EPS8L2,NOV,ACAP2,FAM46A,TRANK1,CNNM4,DAB2IP,EPHB4,PHKA2,MYO5B,DOCK4,SEC23A,PRKCQ,PKMYT1,ATP1B1,C15orf39,ITPR3,ATP10D,SP4,ZNF469,FZD7,NIN,EPHA10,JAK1,CCDC149,SLC27A1,NRG1,KLF5,MLKL,SLC27A3,NR3C2,DENND5B,ARHGEF3,EPS8,HERC5,CYB561,FBXO6,SEPP1,DNAH3,FGF19,SIX4,HLA-A,LGALS3BP,TMCC3,SLC25A36,RASSF8,SNTA1,TMEM87B,RNF128,PTEN,SGK3,SLC44A2,ERBB3,CITED2,TRIM62,SPRY2,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,ARHGEF28,ALDH2,ARAP2,LONRF3,ZC3H11A,MPP1,ZKSCAN2,PARP4,C2orf69,LRRC1,YES1,ARSK,GPLD1,MAMDC4,ACADSB,FGFR2,ERAP1,ETAA1,FZD5,WDR62,SLC25A38,ESPL1,MELK,JARID2,EXPH5,LTBP1,CASP3,HEBP1,CAMKK1,VARS2,MPP5,ERP29,TMC1,TRIM68,PTCHD4,SH3KBP1,CHPF,ABCD4,HTR1D,ARHGEF10L,SIPA1L2,GRHL1,ARHGEF37,SIVA1,CEP78,DLG1,ANKRD12,AKR1B1,SUN3,RP2,MYH14,RASGRP1,CYP1B1,TRIM8,CENPA,RGAG1,ROR1,STK17B,ADRBK2,TYSND1,ARHGEF19,NEIL1,HPSE,MADD,SP6,RAP1GAP,CAPN1,LASP1,ARAP3,ZNF395,PEX6,BVES,ETV5,ABCG2,PM20D2,SAMD9,PHLPP1,ADAMTSL4,KCNN4,COL6A1,C10orf54,RFX5,SLC12A2,GAD1,ALS2CL,CCDC88A,MDFI,PODXL2,OXR1,PDE5A,HEATR5A,PDIK1L,AMDHD1,RANBP9,GLCE,XKRX,BCAR3,SLC6A6,TMEM30A,UTP14C,NFKBIA,SH3BP4,ALPK3,EGFL7,SHROOM2,JAK3,TOB1,RARG,AFAP1,PROM2,CCNE2,LZTFL1,NCKAP5,SPC25,PSME2,HDAC11,PDIA5,MORC4,COL18A1,IL27RA,KCTD9,SLC25A48,SS18,ZNF687,FRYL,ECE1,F2R,PDIA6,SCYL3,FRS3,MAP3K3,GCA,SLC39A8,DOCK5,CASP4,MAP3K6,ALDH5A1,BHLHB9,OVOL1,SPTBN5,ABCA1,LIFR,ANXA3,TSPAN15,LRP4,FAM134A,TGFBR1,COL4A5,NOTUM,TRIB2,SBF1,NTAN1,HDAC9,KIF5B,IRF2BPL,MDM1,TAF1B,ADRBK1,LLGL2,BMP7,GALNS,KIAA0319,ARVCF,CLIP2,MYO5A,PGM1,PHF20L1,SUN2,GCLC,ASPM,MBNL3,TTC7A,ARHGAP24,ENDOD1,HLA-B,C2orf70,TRIM69,RND3,PRCP,SPINT2,UACA,ARRB1,ZMIZ1,GEM,AHR,SNPH |
| 6.960e-09 | -18.78 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6650 | 768 | 17775 | 1757 |
ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,AK7,SLC25A13,RET,CACNA2D2,ISOC2,CA8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,DAPK2,WEE1,MUC4,CYP2S1,TUBG1,ACOX2,PIK3CD,RNF26,TIAM1,MGAT5,APOBEC3G,NWD1,SMARCA2,TNIP1,SH3BGRL,MTRF1L,PRKAR2B,LOXL2,F12,CYP4F3,COL12A1,ABR,PIAS3,ENPP1,CARHSP1,MID1IP1,ATP7B,LIMK1,AGFG2,SERPINB6,RELL1,E2F8,NXT2,ITGA6,MTL5,SLC36A4,GPSM2,MERTK,TTYH3,LMNA,ELF3,RABGGTA,GNS,FRY,MEGF8,RIMS3,FAM13B,NEK2,MAP3K9,CADPS2,ALPK1,ZMYM1,NCAM1,MYLIP,ULBP2,DGKG,PPP6R1,C9orf72,HPS3,SLC37A1,SALL4,MYBL2,NPHP3,SPTLC2,STK17A,PTPRF,CACHD1,NCOA3,SLC4A4,SEMA4D,SETD3,ITPR1,CLMN,AURKA,MDH1,TMEM159,ARPC2,ZNF502,TMEM173,ADAMTS16,DOCK9,ARHGAP11A,PAPSS2,ACTR8,PKP2,TESK2,PRSS22,GRK6,PRKACA,APC2,REPS1,ZNF385B,APPBP2,MUC16,ST5,SCNN1A,CDH1,SNX10,MYT1,TMEM9,SCN3A,TMEM200B,ENPP4,MX1,COL6A2,RIPK2,FZD4,SEPT6,PLEKHO1,SYNE2,NUSAP1,RAB38,SNX12,SHROOM3,CDK19,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,RGS14,MAPK12,TTC8,CKAP2,SDC4,OSGIN2,ANO9,PKN1,PLPPR4,GSTP1,ETS1,SRPX2,TIPRL,HOXB2,NEO1,PDIA4,ADD3,FUT2,ANKS1B,CTSC,FAM102A,TMBIM6,ECI2,WWP1,MAPK11,TPCN1,CRTAP,AMOTL2,ADAMTS2,RAPGEF2,PIK3R1,MRS2,NUB1,SNTB1,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,ACVRL1,NR1D2,CENPE,ITGAV,HMGA1,OSR1,CYBRD1,ACOT7,TLL2,TMEM131,MYL9,SIGIRR,BCAM,KIAA1462,TRIM2,EPAS1,EPHA4,FHDC1,NDC80,TEX2,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,IL6ST,ABCA2,TLN2,MYBL1,DDX59,NEB,CCDC38,ZNF462,PLK1,KCNIP3,CELSR2,STAU2,CBX6,EZR,CR2,ARFRP1,ANLN,LHFPL2,ZBTB7B,RHEB,DZIP1L,OPTN,TRIM9,HS6ST1,MSL1,WIPI1,P4HA2,HOXA9,RAB11FIP1,ARRDC1,PIK3C2B,PIEZO1,EPB41L4A,MYL12B,RMND5A,PRSS8,PRKAA2,RUNX2,HJURP,LGALS3,PDCL,ADCK5,CNTNAP2,NCKAP1,C3orf18,DHRS3,ANO1,B4GALNT1,TNS3,IGF1R,KIF13B,EXOC8,AHCY,PIM1,FAR2,PLCB2,ALDH3A2,ABCC1,CHSY3,PCDH1,PLEKHA6,TESK1,PCBP3,CORO2A,ZNF320,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,IFIT3,G2E3,CDK5R1,FOXD2,MAPKAPK2,PRPS2,SLC2A6,ZDHHC7,LTBP2,PLD1,ZDBF2,SEMA3A,NF2,HOXB7,UPF3B,CTDSPL,XYLT1,TP53,ERBB2,SLC7A2,FAM198B,CYP26A1,SYTL2,ATP6V0B,WDR44,EFR3A,PLCG2,PLK4,GLB1L2,ESPN,NOTCH3,SCN2A,CTH,SULF2,CLCN3,TMTC1,MBP,ERLEC1,AKT1,CDC20,ACO1,DAG1,ATP13A2,DNAJC10,DUOX1,ATP1A1,IDE,PRRT4,PTPRJ,PTK7,STK38,ADAMTS14,SYT13,NDST3,CMTM4,BIN1,CMAS,COL9A3,PINK1,GOLIM4,CDH22,CPEB4,RUSC2,CDCA8,SELL,HMGN3,LBR,PARM1,PPP2R3A,DNAJB9,CD109,FOXP2,ALPP,CDK16,TFAP2A,SGK1,BUB1,FAIM,SYK,ATP2B1,IGDCC4,NFE2L3,DLGAP1,FBLN5,PSMB4,IFITM3,NR3C1,AMFR,PRICKLE1,MAML2,COL7A1,BBS2,BCAR1,MAPK8IP1,DGKE,BSDC1,SCRN2,FUCA1,SERPINA1,FAT4,NAT1,TMC5,NETO2,PGRMC1,NDFIP1,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,TXN,PPP4R4,TTC39B,HSPG2,LGR4,VANGL1,PPFIBP2,TAP1,PLXNA1,NANS,CAMK1D,SLC20A1,SLC9A7,ANKS6,CTGF,ZNF823,STIM1,ZFP36,RGS3,IQCE,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,ATRNL1,IRF2,MARCH2,METAP2,LAMP2,LOC81691,KIFC2,ACVR1C,PBK,CASP9,NBPF3,KIF13A,TNS1,GALNT7,SAV1,SLC25A5,POR,AHRR,ANKRD10,RBM47,GDE1,PLK2,GNPTAB,NKD1,LRIG1,FAM110C,DHTKD1,TANC2,WBSCR27,UNC5B,LZTS1,DDX58,MRC2,MRPL44,CDK17,HLA-E,C6orf106,TNFRSF19,BMP2K,MESDC2,C9orf69,DOPEY2,ITGA3,BHLHE41,SLC16A6,VASN,AIM1,DAPK1,ADCK2,TPST1,PRKG1,TMEM51,SORL1,CACNA1D,TRAK2,IGSF3,GFPT1,PMPCB,KCNJ12,PRODH,KLK5,PRSS23,TBC1D8B,ADCK3,MICB,CALM1,AMER1,ANO6,NPC2,ATP8B3,ANTXR1,NFIB,FRMD4B,MMP15,DGKH,GABRD,SLCO4A1,PLEKHH2,DCK,MATN2,TCEAL4,FAM83D,AGBL5,FGD6,SFMBT1,CABIN1,CDK18,PER3,PLIN3,MAP3K5,IFIH1,NRBP1,FRMPD3,SLC2A4,DLGAP5,TRIP10,ST14,NLRX1,IQGAP1,RALBP1,RPS6KA1,CCDC110,BCL2L1,TMEM170B,CD274,DDR1,AIFM2,ZFYVE9,EPS8L2,NOV,ACAP2,FAM46A,TRANK1,CNNM4,DAB2IP,EPHB4,PHKA2,MYO5B,DOCK4,SEC23A,PRKCQ,PKMYT1,ATP1B1,C15orf39,ITPR3,ATP10D,SP4,ZNF469,FZD7,NIN,EPHA10,JAK1,CCDC149,SLC27A1,NRG1,KLF5,MLKL,SLC27A3,NR3C2,DENND5B,ARHGEF3,EPS8,HERC5,CYB561,FBXO6,SEPP1,DNAH3,FGF19,SIX4,HLA-A,LGALS3BP,TMCC3,SLC25A36,RASSF8,SNTA1,TMEM87B,RNF128,PTEN,SGK3,SLC44A2,ERBB3,CITED2,TRIM62,SPRY2,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,ARHGEF28,ALDH2,ARAP2,LONRF3,ZC3H11A,MPP1,ZKSCAN2,PARP4,C2orf69,LRRC1,YES1,ARSK,GPLD1,MAMDC4,ACADSB,FGFR2,ERAP1,ETAA1,FZD5,WDR62,SLC25A38,ESPL1,MELK,JARID2,EXPH5,LTBP1,CASP3,HEBP1,CAMKK1,VARS2,MPP5,ERP29,TMC1,TRIM68,PTCHD4,SH3KBP1,CHPF,ABCD4,HTR1D,ARHGEF10L,SIPA1L2,GRHL1,ARHGEF37,SIVA1,CEP78,DLG1,ANKRD12,AKR1B1,SUN3,RP2,MYH14,RASGRP1,CYP1B1,TRIM8,CENPA,RGAG1,ROR1,STK17B,ADRBK2,TYSND1,ARHGEF19,NEIL1,HPSE,MADD,SP6,RAP1GAP,CAPN1,LASP1,ARAP3,ZNF395,PEX6,BVES,ETV5,ABCG2,PM20D2,SAMD9,PHLPP1,ADAMTSL4,KCNN4,COL6A1,C10orf54,RFX5,SLC12A2,GAD1,ALS2CL,CCDC88A,MDFI,PODXL2,OXR1,PDE5A,HEATR5A,PDIK1L,AMDHD1,RANBP9,GLCE,XKRX,BCAR3,SLC6A6,TMEM30A,UTP14C,NFKBIA,SH3BP4,ALPK3,EGFL7,SHROOM2,JAK3,TOB1,RARG,AFAP1,PROM2,CCNE2,LZTFL1,NCKAP5,SPC25,PSME2,HDAC11,PDIA5,MORC4,COL18A1,IL27RA,KCTD9,SLC25A48,SS18,ZNF687,FRYL,ECE1,F2R,PDIA6,SCYL3,FRS3,MAP3K3,GCA,SLC39A8,DOCK5,CASP4,MAP3K6,ALDH5A1,BHLHB9,OVOL1,SPTBN5,ABCA1,LIFR,ANXA3,TSPAN15,LRP4,FAM134A,TGFBR1,COL4A5,NOTUM,TRIB2,SBF1,NTAN1,HDAC9,KIF5B,IRF2BPL,MDM1,TAF1B,ADRBK1,LLGL2,BMP7,GALNS,KIAA0319,ARVCF,CLIP2,MYO5A,PGM1,PHF20L1,SUN2,GCLC,ASPM,MBNL3,TTC7A,ARHGAP24,ENDOD1,HLA-B,C2orf70,TRIM69,RND3,PRCP,SPINT2,UACA,ARRB1,ZMIZ1,GEM,AHR,SNPH |
| 7.007e-09 | -18.78 | BLUM_RESPONSE_TO_SALIRASIB_DN | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_DN | 335 | 68 | 17758 | 1761 |
CCNE2,PTTG1,NDC80,SDC1,STIL,BARD1,LTBP3,PLS3,CDKN2C,FOSB,PLK4,TUBG1,TECR,F2R,CYP1B1,CKS2,PLK1,CENPA,SLC39A8,PBK,CDC20,NUSAP1,CCNF,H2AFV,CDK1,PRIM1,DPYSL3,PIAS3,CARHSP1,BFSP1,HDAC1,HSPB1,PACSIN2,SOX9,KIF23,GPSM2,ISYNA1,CRABP2,TSPAN7,LMNA,TOP2A,TNS3,RANBP1,NEK2,OPN3,BUB1,RFX5,MCCC2,HMMR,SHMT1,ZWINT,KIF20A,PRSS23,MYBL2,HMG20B,KIF11,FOS,CYB5A,TWSG1,PLOD2,DCK,MATN2,AURKA,NR4A2,UBE2C,CCNB2,ESPL1,ZBTB33 |
| 7.307e-09 | -18.73 | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | 471 | 87 | 17758 | 1761 |
SUN1,AVPI1,ATP2C2,C5orf30,CCDC68,PRSS22,CD274,OSR2,BCL2L1,GRK6,KCTD9,SIPA1L2,ZFP36,OSBPL3,IL6ST,ANKRD12,DUSP10,RCAN3,PTPRE,ZNF365,TIAM1,DDX59,MYO5B,NLRP4,ATL1,CITED4,COQ10B,SAT1,PTGER4,TFAP2C,DUSP4,DOCK5,ZFAND5,RNF19B,STK17B,IRS2,GPRC5B,SHROOM3,CAB39,ST3GAL1,DDX58,ARHGEF3,PARP12,CDK17,PPP1R2,ENO2,ATP9A,RUSC2,SDC4,SOX9,ARL4C,B4GALT4,PARM1,BMP2K,AKIRIN1,RASSF8,AIM1L,ITGB8,CYR61,CALD1,SGK1,PIM1,SPRY2,FAM69A,SOCS5,AMOTL2,ARAP2,B3GNT2,RGMB,FAM160A1,GCLC,SYBU,EIF5A2,NPHP3,BCAR1,C3orf58,STK17A,BCAR3,PRKAG2,KBTBD2,MATN2,PGM2L1,HIPK3,AHR,KLF7,JARID2,EHD1 |
| 7.917e-09 | -18.65 | cell morphogenesis involved in neuron differentiation | biological process | GO:0048667 | 719 | 122 | 16441 | 1675 |
MYL9,SPRED1,PSME2,RPS6KA1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,ARTN,SHC3,DPYSL2,DACT1,DLG1,TRPC1,DAB2IP,NTN4,MYH14,EPHB4,RASGEF1A,DLG3,BTBD3,TIAM1,ETV4,RASGRP1,FRS3,SEMA3B,ATL1,COL6A2,CELSR2,EZR,PRKCQ,SLC11A2,ALCAM,DAG1,MYL12A,ARHGAP35,DPYSL3,EPHA10,IRS2,PLCG1,JAK1,MAP2,LIMK1,SLC9A6,SPTBN5,NRG1,EFNA5,UNC5B,COBL,MYL12B,SCN5A,COL9A3,ARHGEF11,RASA2,LRP4,CALM3,PSMD10,COL4A5,SLC1A3,PLPPR4,SPR,EFNB1,FGF19,NRP2,NEO1,KIF5B,IGF1R,PTEN,BMP7,FLRT3,COL6A1,ERBB3,CACNA1D,NCAM1,WNT3A,S100A6,FARP2,DPYSL5,RASGRF1,HES1,ARHGEF28,B3GNT2,RHOA,PSMB4,FMN1,RGMB,RAPGEF2,CALM1,GRIN1,SCRIB,YES1,EPHA1,RANBP9,NFIB,PSMA4,RASA1,CDK5R1,CNTNAP1,FGFR2,SEMA4D,MATN2,RYK,NR4A3,PGRMC1,PITPNA,GRIN2D,NR4A2,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 8.068e-09 | -18.64 | negative regulation of protein modification process | biological process | GO:0031400 | 584 | 104 | 16441 | 1675 |
CASP3,SPRED1,PPP4R4,NF2,FOXM1,DNAJC3,PSME2,CTDSPL,NDRG2,PSME1,CCNB1,SYTL2,CALM2,CDKN2C,SVBP,PSMD1,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,CRY2,TWIST1,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,PLK1,SIRT1,CAMSAP3,TNIP1,AKT1,ITCH,PBK,CDC20,EZR,PRKAR2B,PKMYT1,DUSP4,DAG1,SOCS3,PIAS3,ENPP1,DNAJC10,PTPRJ,CORO1C,LIMK1,STK38,TRAF3IP1,RGS14,HSPB1,F2RL1,ARFGEF3,PINK1,LMTK3,CDKN1C,DNAJB2,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,GSTP1,FBLN1,TIPRL,SH2D4A,MECOM,CD109,SNTA1,TFAP4,IGF1R,PTEN,BMP7,BAX,TRIM21,SORL1,BUB1,SPRY2,CRTAP,SOCS5,PSMB4,GCLC,CALM1,HMG20B,EPHA1,PSMA4,RANBP9,MAPK8IP1,CDK5RAP1,SWAP70,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,GPER1,LRRK1,UBE2C,HIPK3,PKIA,JARID2,XDH |
| 8.335e-09 | -18.60 | negative regulation of cell communication | biological process | GO:0010648 | 1144 | 176 | 16441 | 1675 |
SIGIRR,LTBP1,LGR4,NDRG2,PSME1,SYTL4,GRM5,SH3KBP1,PSMD1,IL6ST,CABP1,RGS3,TSPAN6,DLG1,DUSP10,CRY2,CTTN,PTPRE,TNIP1,ACVR1C,ITCH,PBK,SLC35C1,EZR,SLC25A5,OPTN,CXXC4,ENPP1,ANKRD6,PLK2,TRAF3IP1,MADD,NKD1,RAB11FIP1,NOD2,PRKCDBP,HDAC1,UNC5B,HSPB1,F2RL1,LZTS1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,RASA2,UBASH3B,SOX9,PHLPP1,FBLN1,DHRS3,LMNA,MECOM,ITGA3,IGF1R,PIK3AP1,GATA2,VASN,DAPK1,SORL1,WNT3A,GPR161,MDFI,SOCS5,CYP26B1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,G2E3,PLIN5,RASA1,ONECUT1,NFKBIA,ITPR1,SH3BP4,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,SPRED1,NF2,FOXM1,NLRX1,INPP5D,DDIT4L,PSME2,RGS20,TP53,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,IER3,CCND1,NOV,DACT1,BCL6,DAB2IP,TWIST1,LGMN,CDKN2D,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,PRKCQ,ERBB2IP,DUSP4,DAG1,ARHGAP35,SOCS3,PTPRJ,STK38,WFS1,TRABD2A,TLE1,NRG1,RGS14,CTHRC1,GCLM,PINK1,NKX3-1,LRP4,PSMD10,TGFBR1,AES,NOTUM,GSTP1,PPP2R3A,FZD6,HMGXB4,CD109,CTNNBIP1,CARD8,ADORA1,ADRBK1,PTEN,BMP7,BAX,TMBIM6,ERBB3,FAIM,SPRY2,TGIF1,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,PELI3,MAPK8IP1,ARHGAP24,BANK1,SCG2,TWSG1,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 8.510e-09 | -18.58 | KIM_WT1_TARGETS_12HR_UP | MSigDB lists | KIM_WT1_TARGETS_12HR_UP | 154 | 40 | 17758 | 1761 |
MYL9,ENO2,DLGAP5,ZNF395,LGR4,ATP9A,ZCCHC24,LRP4,RASSF7,SOX9,EPS8,GDF15,TRIB2,PJA2,DDR1,SLC20A1,KIF5B,TNS3,ADORA1,DOK4,BHLHE41,RUNDC3B,UBE2J1,IFIT1,KLF9,TLN2,MYBL1,ULBP2,GFPT1,OXR1,PLEKHO1,HSPA12A,ATP1B1,FZD7,ENDOD1,TIMP3,KCNK1,P4HA2,CSF1,ZMIZ1 |
| 8.579e-09 | -18.57 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 47 | 17758 | 1761 |
TXN,ENO2,UGP2,DEPDC1,GNPDA1,SLC25A13,GNE,SOX9,PKP2,IL13RA1,B4GALT4,SDC1,MERTK,CHPF,ELF3,IER3,ARTN,XYLT2,FUT8,TPST1,GOT1,ALDH7A1,PHKA2,EGLN3,CITED2,CTH,HMMR,B3GALT6,GFPT1,CENPA,KIF20A,GUSB,COG2,GCLC,AK4,PDK3,IDH1,CDK1,CYB5A,GLCE,IRS2,PLOD2,P4HA2,AURKA,MDH1,NDST3,RRAGD |
| 8.599e-09 | -18.57 | PH | smart domains | SM00233 | 278 | 63 | 9131 | 997 |
ARAP3,ARHGEF3,ARHGEF11,CIT,RASA2,TEX2,TEC,SBF1,PHLPP1,PHLDA1,ARHGEF40,SPTB,ARHGEF16,SNTA1,ACAP2,ADRBK1,RALGPS2,ELMO2,DOK4,OSBPL3,PLCG2,EXOC8,PLEKHF1,DAB2IP,RTKN2,CADPS2,TIAM1,FARP2,RASGRF1,ARHGEF28,ARAP2,PLEKHA6,AKT1,SNTB2,PLEKHO1,SPATA13,SNTB1,ANLN,ADRBK2,RASA1,ABR,ARHGEF26,ARHGAP24,DGKH,IRS2,PLCG1,PLCH1,PLEKHG6,SWAP70,ARHGEF19,PLEKHH2,TRIOBP,PLEKHG1,FGD6,SPTBN5,PLD1,AFAP1,GAB1,ARHGEF9,DEF6,DOCK9,ARHGEF4,FGD1 |
| 8.634e-09 | -18.57 | regulation of programmed cell death | biological process | GO:0043067 | 1414 | 209 | 16441 | 1675 |
CASP3,TRIM2,TSC22D3,DNAJC3,RET,PSME1,CAMK1D,HDAC6,BARD1,ERP29,CARD10,EPCAM,DAPK2,PSMD1,RPS6KA2,CTGF,IL6ST,SIVA1,ALDH1A3,IL31RA,MITF,PIK3CA,CTTN,SLC39A10,TIAM1,CYP1B1,PLK1,KCNIP3,ACVR1C,ITCH,CASP9,SAV1,PRKRA,SLC25A5,CDK1,POR,STK17B,ARF4,ABR,OPTN,MDK,SLC25A4,DNM1L,PLK2,MADD,NOD2,HDAC1,KLF11,UNC5B,HSPB1,TRAF5,FGD1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,SLC25A27,PHLPP1,ADAMTSL4,MERTK,LMNA,MECOM,TFAP4,IGF1R,CYR61,DAPK1,MAP3K9,TNFRSF12A,MYDGF,PIM1,WNT3A,OXR1,ANO6,STRADB,SCRIB,IFIT3,PSMA4,G2E3,RASA1,CDK5R1,FAS,STK17A,SEMA4D,NFKBIA,AURKA,NR4A2,STK39,GDF11,MAP3K5,JAK3,RARG,IFI6,XDH,NQO1,THRA,INPP5D,RPS6KA1,PSME2,CAST,TP53,ERBB2,COL18A1,CD274,BCL2L1,AIFM2,PHLDA1,STIL,BCAP31,ARHGEF16,IER3,SP100,KIF14,PLCG2,BCL6,CDKN1B,DAB2IP,TWIST1,LGMN,EGLN3,CDKN2D,F2R,CTH,SIRT1,PPIF,RIPK2,AKT1,FIGNL1,HTATIP2,PRKCQ,SLC11A2,GLO1,CD40,MAP3K6,CASP4,SOCS3,IRS2,CDK19,STK26,NGFRAP1,BHLHB9,AXL,WFS1,TLE1,NRG1,IRF7,LIFR,BIN1,GCLM,ARHGEF3,PINK1,NKX3-1,CPEB4,ARHGEF11,DAP,PDIA3,PSMD10,SELL,TGFBR1,AES,GDF15,ETS1,GSTP1,BEX2,SIX4,TOP2A,CARD8,ADORA1,CTSC,PTEN,BMP7,CST3,TFAP2A,BAX,SGK3,SGK1,PLEKHF1,TMBIM6,BUB1,ERBB3,CITED2,FAIM,SPRY2,OSGIN1,RHOA,PSMB4,RAPGEF2,PLAUR,GCLC,PIK3R1,GRIN1,RGCC,PELI3,BCAR1,MAPK8IP1,GPLD1,FGFR2,SCG2,DHRS2,NR4A3,ARRB1,ITGAV,GPER1,SOX8,OSR1,ARHGEF9,HIPK3,MELK,ARHGEF4 |
| 8.660e-09 | -18.56 | wound healing | biological process | GO:0042060 | 667 | 115 | 16441 | 1675 |
PLA2G4A,MYL9,CASP3,PAPSS2,INPP5D,TP53,ERBB2,F11R,ITPR2,CCNB1,PRKACA,PDGFB,SDC1,DDR1,CALM2,PDGFA,WEE1,NOV,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,CDH3,EPB41L4B,LMAN1,F2R,RASGRP1,LAMP2,ENPP4,AKT1,KLK6,PRKAR2B,PRKCQ,ATP1B1,F12,CD40,ITPR3,MYL12A,FZD7,OPTN,PLCG1,KCNMB4,ARHGEF19,HPSE,ABHD12,PTK7,AXL,HDAC1,NRG1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SDC4,CALM3,KIF23,SELL,TGFBR1,TEC,ETS1,MERTK,FBLN1,SIRPA,FZD6,ITGA3,CYR61,GATA2,CD9,PRKG1,ADAM15,ERBB3,WNT3A,DGKG,SYK,ATP2B1,ELK3,RHOA,PLSCR1,BCL9,PLAUR,CALM1,PIK3R1,ANO6,PPARA,C1GALT1C1,HMG20B,PDE5A,SCRIB,YES1,KIF11,BCAR1,GNA11,DGKE,RASGRP2,DGKH,GNAS,ARHGAP24,TIMP3,SERPINA1,SYT7,ACVRL1,PRCP,ITPR1,ARRB1,ITGAV,ATP1B3,CENPE,L1CAM,DOCK9,EHD1 |
| 8.917e-09 | -18.54 | REICHERT_MITOSIS_LIN9_TARGETS | MSigDB lists | REICHERT_MITOSIS_LIN9_TARGETS | 28 | 15 | 17758 | 1761 |
HMMR,TOP2A,PLK1,CENPA,KIF20A,ASPM,CALD1,KIF23,AURKA,CDCA2,NUSAP1,CENPE,CCNF,CCNB1,G2E3 |
| 8.995e-09 | -18.53 | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 191 | 46 | 17758 | 1761 |
MTM1,REPS2,FBXO2,PBX3,NDUFA4,PJA2,SCML1,ZFYVE16,FRY,UBE2J1,OSTF1,PIM1,PIKFYVE,CLIP2,CCDC88A,SOCS5,LOC81691,PDGFC,RHOA,CD55,SAT1,CR2,YES1,PCTP,ATP10D,FUCA1,PIAS3,HLA-B,MFAP3L,PRKAG2,JAK1,H1F0,CSF1,DBI,RAP2C,PPM1H,RYK,FAM117A,ZDHHC7,CAB39,ADIPOR1,ARPC2,NDFIP1,JARID2,RRAGD,CD33 |
| 8.995e-09 | -18.53 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | 191 | 46 | 17758 | 1761 |
ENO2,CPEB4,AK7,FRMD6,CAMKK1,UBASH3B,ITGA6,ETV5,SDC4,SELL,NDRG2,TGFBR1,BCL2L1,MGST2,NUCB2,PHLPP1,IL17RB,ITGB8,FAM46A,TPST1,KLC3,WWP1,PIM1,RASGEF1A,NEB,SULF2,GFPT1,SYPL1,LCA5,MPP1,MBNL3,IGSF8,DUSP4,SESN1,CYB5A,CMTM7,CD83,NCOA3,CDKN2AIPNL,SWAP70,TIMM8A,TWSG1,GRAMD1C,TANC2,LTA4H,RRAGD |
| 9.119e-09 | -18.51 | molecular function regulator | molecular function | GO:0098772 | 1207 | 183 | 16491 | 1673 |
CASP3,PPP4R4,DNAJC3,CACNA2D2,ARFGEF1,PSME1,PDGFB,DENND2D,ARHGEF10L,CALM2,CDKN2C,SIPA1L2,PSMD1,ARHGEF37,STIM1,RGS3,CABP1,DLG1,PIK3CA,KCNS3,RP2,RCAN3,TIAM1,RASGRP1,KCNIP3,CASP9,ARHGDIB,PRKAR2B,PIF1,PRKRA,PPP1R14C,ARHGEF26,ABR,PIAS3,PLEKHG6,ARHGEF19,KCNMB4,GPRC5B,MADD,AGFG2,CAB39,SERPINB6,SERPINI1,RAP1GAP,HSPB1,FGD1,ARAP3,SERPINE2,PPP1R2,CDKN1C,TBC1D1,RASA2,FXYD3,CALM3,GPSM2,FBLN1,HPCAL4,BMP2K,RALGPS2,RINL,FAM13B,RANBP1,TBCD,PPP4R1,PRKG1,FXYD5,WNT3A,ALS2CL,TBC1D8B,CALM1,SPATA13,RASA1,CDK5R1,RASGRP2,BCAR3,MMP15,PRKAG2,ITPR1,SH3BP4,FGD6,CTSA,CABIN1,ATP1B3,SERPINB1,DOCK9,CCNE2,ARHGAP11A,SPRED1,CCDC109B,PSME2,RPS6KA1,CAST,IQGAP1,RALBP1,PTTG1,TP53,RGS20,PKP2,MGST2,ARHGEF16,EPS8L2,CCND1,APLP2,ST5,ACAP2,SH3BP1,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,GM2A,CHP1,CKS2,DOCK4,TIMP2,AKT1,ATP1B1,DOCK5,ARHGAP35,SOCS3,DNAJC10,PPP2R5A,NGFRAP1,MMP17,SIPA1L1,PLEKHG1,NRG1,EFNA5,RGS14,PPP2R2D,DENND5B,ARFGEF3,ANXA3,GCLM,ARHGEF3,PCOLCE,PINK1,NKX3-1,DEPDC1,ARHGEF11,TRIB2,SBF1,GSTP1,ARHGEF40,PPP2R3A,SNTA1,CD109,CARD8,LLGL2,CTSC,CST3,SGK3,SGK1,TMBIM6,TSPAN13,ERBB3,IQGAP3,SPRY2,NCOA2,FARP2,RASGRF1,ARAP2,ARHGEF28,RAPGEF2,PIK3R1,FURIN,RGCC,COL7A1,GRTP1,MAPK8IP1,GPLD1,CDK5RAP1,ARHGAP24,TIMP3,SERPINA1,SPINT2,ARRB1,TBC1D4,CPEB2,ARHGEF9,PKIA,RAB3IL1,ARHGEF4 |
| 1.036e-08 | -18.39 | regulation of protein modification process | biological process | GO:0031399 | 1701 | 243 | 16441 | 1675 |
CASP3,TXN,PPP4R4,DNAJC3,CAMKK1,EPHA4,ARFGEF1,FBXO2,NRG2,NDRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,FANCI,CALM2,CDKN2C,PSMD1,CTGF,NPNT,SHC3,IL6ST,RGS3,IL31RA,PIK3CA,DLG1,DUSP10,CRY2,SLC39A10,RASGRP1,PLK1,TNIP1,ITCH,PBK,EZR,PRKAR2B,CDK1,KDM4D,PIAS3,ENPP1,PLCG1,GPRC5B,ANKRD6,LIMK1,TRAF3IP1,MADD,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,LMTK3,PPP1R2,CDKN1C,NUAK1,DNAJB2,UBASH3B,RASA2,SOX9,CALM3,TEC,PHLPP1,FBLN1,MECOM,TFAP4,IGF1R,CYR61,GATA2,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,PPP6R1,CCDC88A,MDFI,SOCS5,MMD,CALM1,PDE5A,STRADB,HMG20B,EIF2AK1,EPHA1,PSMA4,RANBP9,RASA1,CDK5R1,FAS,FECH,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,FAM83D,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,CCNE2,SPRED1,AVPI1,NF2,FOXM1,IL15,IQGAP1,PSME2,CTDSPL,TP53,ERBB2,PRKACA,EMP2,STIL,SYTL2,CCND1,PDGFA,SVBP,APLP2,ST5,DACT1,KIF14,BCL6,CDKN1B,DAB2IP,TWIST1,PDE4D,RASGEF1A,DLG3,CDKN2D,F2R,CTDSP2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,CAMSAP3,TIMP2,RIPK2,AKT1,FZD4,CDC20,CDCA2,PKMYT1,DUSP4,CD40,DAG1,MAP3K6,FZD7,SOCS3,IRS2,DNAJC10,PTPRJ,JAK1,PPP2R5A,STK26,CORO1C,WFS1,STK38,SLC27A1,EFNA5,SPTBN5,NRG1,RGS14,PPP2R2D,ARFGEF3,PINK1,NKX3-1,LRP4,SDC4,PSMD10,HERC5,TGFBR1,GDF15,PKN1,TRIB2,GSTP1,FGF19,TIPRL,PPP2R3A,SH2D4A,CD109,SNTA1,DIRAS3,ADORA1,PTEN,BMP7,BAX,TRIM21,BUB1,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,CRTAP,HES1,PDGFC,RASGRF1,PSMB4,GCLC,RAPGEF2,PLAUR,GRIN1,RGCC,PRICKLE1,YES1,MAPK8IP1,GPLD1,CDK5RAP1,BANK1,SWAP70,FGFR2,ACVRL1,RAP2C,NMI,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,NDFIP1,UBE2C,HIPK3,PKIA,JARID2 |
| 1.038e-08 | -18.38 | regulation of multicellular organismal process | biological process | GO:0051239 | 2431 | 328 | 16441 | 1675 |
ACACB,GAA,SSH1,LGR4,TSC22D3,RET,CACNA2D2,IL18,PLXNA1,CAMK1D,CCNB1,VASH1,FAM101B,GRM5,NCS1,CALM2,CTGF,ZFP36,PIK3CA,TACSTD2,SEMA3G,PACSIN1,TIAM1,ACVR1C,TFAP2C,LOXL2,F12,SAV1,POR,ABR,ENPP1,PLCG1,PLK2,LIMK1,TRAF3IP1,NKD1,NOD2,BMP1,ITPKA,ARF6,HSPB1,F2RL1,LZTS1,DDX58,SEMA6B,SCN5A,HLA-E,SOX9,BMP2K,ITGA3,CYR61,MEGF8,FLRT3,VASN,PRKG1,SORL1,TNFRSF12A,MYDGF,CACNA1D,MYLIP,RIMS2,GPR161,SOCS5,EPB41L5,KCNJ12,MMD,CALM1,ANO6,EPHA1,NPHP3,GNA11,NFIB,FAS,PTPRF,NCOA3,SEMA4D,AURKA,SFMBT1,NR4A2,STK39,GDF11,PER3,IFIH1,TMEM173,XDH,EGLN1,FOXO6,GRHL2,NLRX1,THRA,INPP5D,IQGAP1,PKP2,CD274,PRKACA,TNFSF9,CCND1,NOV,SP100,FAM46A,CDKN1B,DAB2IP,PDE4D,LGMN,ETV4,SEMA3B,DOCK4,ENPP4,SSH3,RIPK2,HTATIP2,PRKCQ,ATP1B1,SP4,FZD7,CORO1C,AXL,SIPA1L1,INPP4B,SLC27A1,NRG1,RGS14,COBL,WASF3,CTHRC1,NKX3-1,PBX3,HERC5,ETS1,SPR,GSTP1,SRPX2,TEAD3,HLA-A,ADGRB2,SIX4,SGPL1,CTNNBIP1,SNTA1,RNF128,PTEN,CST3,BAX,MAPK11,CITED2,TRIM62,TGIF1,RAPGEF2,PIK3R1,GRIN1,FURIN,FOS,GPLD1,CDK5RAP1,FGFR2,ACVRL1,NR1D2,TBX18,NR4A3,ERAP1,GRIN2D,GPER1,FZD5,OSR1,ARSB,MYL9,EMX1,SIGIRR,EPAS1,EPHA4,LMCD1,NDRG2,F11R,HDAC6,PDGFB,NPNT,IL6ST,DPYSL2,PASK,MITF,DLG1,DUSP10,NTN4,CTTN,RASGRP1,CYP1B1,THRB,NLRP4,ITCH,EZR,ARHGDIB,KLK6,CDK1,RHEB,DPYSL3,KCNMB4,GPRC5B,AGPAT2,HPSE,HOXA9,RAB11FIP1,SP6,MAFF,PRKAA2,GRN,RUNX2,LGALS3,SERPINE2,BVES,UBASH3B,ETV5,CALM3,TEC,PHLPP1,DHRS3,FBLN1,IL18R1,CA2,GATA2,KIF13B,SUCO,C10orf54,WNT3A,CCDC88A,HMG20B,PDE5A,CDK5R1,SOX13,GNAS,MAPKAPK2,PLPP3,CSF1,TMEM30A,NFKBIA,NLRC5,FAM213A,JAK3,SEMA3A,TOB1,RARG,GAS2L1,NF2,HOXB7,IL15,TP53,ERBB2,IL27RA,OSR2,EMP2,SYTL2,PDGFA,SVBP,KIF14,PLCG2,BCL6,CDH3,TWIST1,DIXDC1,ECE1,EPB41L4B,TMEM64,NOTCH3,F2R,DVL2,SULF2,TIMP2,AKT1,CDC20,CCSAP,PTGER4,CD40,DOCK5,DAG1,ARHGAP35,ATP1A1,BHLHB9,PTK7,IRF7,EFNA5,BIN1,ANXA3,ADGRG1,CIT,LRP4,TGFBR1,CRABP2,TRIB2,PPP2R3A,NRP2,FZD6,HDAC9,CD109,CARD8,ADRBK1,ADORA1,BMP7,MYCL,KIAA0319,UBE2J1,TFAP2A,SGK1,TRIM21,IQGAP3,SYK,TLE6,HES1,RHOA,PLAUR,ASPM,LITAF,RGCC,PRICKLE1,BBS2,BCAR1,PRDX4,CD83,HLA-B,BANK1,FAT4,TWSG1,PRCP,NMI,DTX4,ARRB1,PPP2R3C,SOX8,NDFIP1,L1CAM |
| 1.042e-08 | -18.38 | neuron differentiation | biological process | GO:0030182 | 1196 | 182 | 16441 | 1675 |
MYL9,CASP3,EMX1,UGT8,CUL4B,RET,EPHA4,ARFGEF1,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,TMC1,PLS3,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,DLG1,TRPC1,NTN4,CTTN,MYH14,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,CELSR2,EZR,TFAP2C,ARF4,DPYSL3,HS6ST1,PLCG1,MAP2,LIMK1,NKD1,UNC5B,MYL12B,SCN5A,RUNX2,CDKN1C,RASA2,SOX9,CALM3,CNTNAP2,SLC1A3,IGF1R,FRY,GATA2,FLRT3,MEGF8,COL6A1,PRKG1,CACNA1D,NCAM1,WNT3A,DGKG,DPYSL5,RGMB,CALM1,SCRIB,EPHA1,NFIB,PSMA4,RANBP9,STX3,RASA1,CDK5R1,PTPRF,SEMA4D,MATN2,CLMN,AURKA,PITPNA,NR4A2,ARPC2,JAK3,SEMA3A,KLF7,EHD1,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,PHLDA1,PDGFA,ARTN,CDH1,DACT1,LMO4,FRYL,LHX6,DAB2IP,ACSL4,NOTCH3,EPHB4,DLG3,RASGEF1A,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,NFIX,ARHGAP35,EPHA10,IRS2,JAK1,SLC9A6,SPTBN5,NRG1,EFNA5,LIFR,COBL,COL9A3,CTHRC1,ARHGEF11,CIT,LRP4,SDC4,PSMD10,PBX3,COL4A5,TGFBR1,PLPPR4,SPR,FGF19,EFNB1,PPP2R3A,NRP2,NEO1,HDAC9,KIF5B,IGSF9,PTEN,CDK16,BMP7,ATP8B1,SGK1,ERBB3,S100A6,FARP2,RASGRF1,HES1,B3GNT2,RHOA,ARHGEF28,PSMB4,FMN1,RAPGEF2,GRIN1,STMN3,RUNX3,YES1,PITX2,CNTNAP1,FAT4,FGFR2,RYK,PGRMC1,NR4A3,GRIN2D,ITGAV,FZD5,SOX8,L1CAM,RGMA |
| 1.045e-08 | -18.38 | skin-malignant_melanoma | COSMIC cancer mutations | skin-malignant_melanoma | 16562 | 1690 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.062e-08 | -18.36 | CROONQUIST_IL6_DEPRIVATION_DN | MSigDB lists | CROONQUIST_IL6_DEPRIVATION_DN | 98 | 30 | 17758 | 1761 |
HMMR,CCNE2,PLK1,ZWINT,CENPA,SPC25,FOXM1,AASS,PTTG1,CDC20,MYBL2,GGH,CCNF,CCNB1,STIL,KIF11,CDK1,FANCI,TOP2A,WEE1,KIF14,PLK4,AURKA,BUB1,HMGA1,CENPE,CCNB2,UBE2C,SEPHS1,CKS2 |
| 1.091e-08 | -18.33 | Axon guidance | REACTOME pathways | R-HSA-422475 | 516 | 96 | 8202 | 867 |
MYL9,SPRED1,PSME2,RPS6KA1,IQGAP1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,ARTN,SHC3,DPYSL2,DLG1,DUSP10,TRPC1,DAB2IP,NTN4,EPHB4,MYH14,SCN2A,DLG3,RASGEF1A,TIAM1,RASGRP1,SCN3A,FRS3,COL6A2,EZR,PRKCQ,DUSP4,ALCAM,MYL12A,DPYSL3,ARHGAP35,EPHA10,IRS2,PLCG1,PPP2R5A,JAK1,LIMK1,EFNA5,NRG1,SPTBN5,UNC5B,MYL12B,COL9A3,SCN5A,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,FGF19,EFNB1,NRP2,NEO1,COL6A1,ERBB3,CACNA1D,NCAM1,FARP2,DPYSL5,RASGRF1,ARHGEF28,RHOA,PSMB4,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,RANBP9,PSMA4,CDK5R1,RASA1,CNTNAP1,SEMA4D,FGFR2,ARRB1,PITPNA,GRIN2D,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,RGMA |
| 1.096e-08 | -18.33 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 17299 | 1742 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.131e-08 | -18.30 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 318 | 65 | 17758 | 1761 |
UPF3B,PAPSS2,TSC22D3,TMEM41B,NANS,STIL,APLP2,BTG3,SCNN1A,CDH1,LMO4,KIF14,DUSP10,ACOX2,BTBD3,S100A13,RASGRP1,LAMP3,S100A4,CDC20,PRKAR2B,GALNT7,DUSP4,IDH1,ALCAM,OPTN,RBM47,INPP4B,KLF5,DAP,BLVRB,HERC5,KIF23,CYB561,CNTNAP2,S100A2,SEPP1,PSIP1,LBR,HOXB2,TOP2A,MLPH,FJX1,LIMCH1,TSPAN13,CADPS2,GPR161,CCDC88A,S100A6,TRAK2,SOCS5,FAH,PLSCR1,KIF20A,PIK3R1,AK4,KIF11,SPTLC2,CYB5A,SWAP70,DHRS2,DBI,SH3BP4,UBE2C,MELK |
| 1.131e-08 | -18.30 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 318 | 65 | 17758 | 1761 |
TRIM2,UGT8,NQO1,FOXM1,TSC22D3,PTTG1,RET,NDC80,CACNA2D2,C5orf30,STIL,APPBP2,BTG3,SCNN1A,KIF14,IL6ST,LMO4,REEP1,TSPAN1,SEPHS1,CPD,CENPA,CDC20,GALNT7,RBM47,SLC9A6,CORO1C,WFS1,ATP7B,INPP4B,KLF5,ANXA9,HSPB1,LASP1,CDK17,ALDH6A1,MTL5,GDF15,GSTP1,LBR,MLPH,SLC16A6,FUT8,TFAP2A,ECI2,TSPAN13,WWP1,BUB1,MCCC2,GPR161,NFE2L3,SYBU,BLVRA,SPTLC2,NFIB,MFSD7,PRDX4,AP1AR,ACADSB,DHRS2,NAT1,TCEAL4,ARHGEF9,TOB1,MELK |
| 1.181e-08 | -18.25 | colon | COSMIC cancer mutations | colon | 17300 | 1742 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.208e-08 | -18.23 | lung-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour-atypical | 522 | 93 | 17775 | 1757 |
NF2,VANGL1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,LPIN3,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,FAM46A,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,ADRBK2,STK17B,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,HDAC1,MLKL,PPP2R2D,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,ACVRL1,FGFR2,P4HA3,UACA,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 1.218e-08 | -18.22 | GOZGIT_ESR1_TARGETS_UP | MSigDB lists | GOZGIT_ESR1_TARGETS_UP | 138 | 37 | 17758 | 1761 |
ACACB,UGT8,DEPDC1,KCTD12,IL18,B4GALT4,ADAMTSL4,BMP2K,CYP26A1,FRY,GRHL1,ALPP,GATA2,TFAP2A,LIMCH1,CACNA1D,PIM1,C10orf54,SLC39A10,NAGA,SLC16A5,SGCE,SEPT6,PTGER4,PRKAR2B,FOS,COL12A1,CRISPLD2,ALDH3B1,PRKAG2,DHRS2,GRAMD1C,PLD1,FHL1,PROM2,ABCG1,XDH |
| 1.297e-08 | -18.16 | protein kinase activity | molecular function | GO:0004672 | 599 | 105 | 16491 | 1673 |
LTBP1,CAMKK1,RPS6KA1,RET,EPHA4,TESK2,ERBB2,GRK6,CAMK1D,CCNB1,PRKACA,DDR1,CCND1,DAPK2,WEE1,RPS6KA2,PASK,PIK3CA,PLK4,EPHB4,PHKA2,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,XRCC6BP1,MAP3K6,STK17B,CDK1,ADRBK2,EPHA10,JAK1,STK26,CDK19,PTK7,LIMK1,STK38,PLK2,AXL,MLKL,ITPKA,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,SOX9,ADCK5,TGFBR1,TEC,PKN1,TRIB2,MERTK,BMP2K,NRP2,IGF1R,ADRBK1,CDK16,DAPK1,MAP3K9,ADCK2,PRKG1,NEK2,SGK3,SGK1,MAPK11,BUB1,ERBB3,PIM1,ALPK1,MAST4,SYK,MMD,TESK1,STRADB,EIF2AK1,YES1,EPHA1,PDK3,PDIK1L,CDK5R1,STK17A,MAPKAPK2,PRKAG2,FGFR2,ACVRL1,CSNK1G1,RYK,AURKA,ALPK3,CDK18,STK39,LRRK1,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 1.333e-08 | -18.13 | AMIT_SERUM_RESPONSE_120_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_120_MCF10A | 63 | 23 | 17758 | 1761 |
SUN1,CD55,CDKN1C,TESK1,PLAUR,SOX9,C3orf52,SERTAD3,EZR,BCAR3,IRS2,ETS2,RND3,SETD3,CSTF2,ATP8B1,TRIM21,DUSP10,KLF5,PIM1,MAFF,ISOC1,GCNT1 |
| 1.336e-08 | -18.13 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 187 | 45 | 17758 | 1761 |
SIGIRR,HECA,TSC22D3,TMEM41B,HLA-F,EPHA4,TMX4,ARL4C,FAM46C,DNAJB9,TMEM63A,SCML1,MARCH8,RASSF8,ADD3,FAM46A,LYPD3,MGAT4A,KLF3,FOSB,SORL1,SGK1,CRY2,IFIT1,CITED2,MYLIP,TIPARP,CKAP4,ATP2B1,IFITM3,COQ10B,PIK3R1,PTGER4,ITPR3,FNDC3A,FOS,RASGRP2,IRS2,RAB11FIP2,NR4A2,KLF11,PIK3C2B,NR3C2,TOB1,KLF7 |
| 1.350e-08 | -18.12 | endometrium | COSMIC cancer mutations | endometrium | 16541 | 1688 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,GEM,L1CAM,SNPH |
| 1.350e-08 | -18.12 | cellular response to organic substance | biological process | GO:0071310 | 2021 | 280 | 16441 | 1675 |
SSH1,ADD1,IL15RA,DNAJC3,RET,NRG2,PSME1,IL18,CCNB1,CALM2,CYP1A1,PSMD1,CTGF,IL31RA,KLF3,FOSB,PIK3CA,IRF2,PIK3CD,TIAM1,TIPARP,CASP9,AGO4,PRKAR2B,POR,ABR,ENPP1,PLCG1,NOD2,HDAC1,EIF4EBP2,HSPB1,GAB1,FGD1,HLA-E,SOX9,TNFRSF19,LMNA,TFAP4,MEGF8,FLRT3,DAPK1,TNFRSF12A,CD70,MYDGF,NCAM1,NUP85,SOCS5,PAQR7,EPB41L5,GFPT1,STAT4,CALM1,ERO1A,ELK1,PSMA4,RASA1,FAS,NCOA3,PRKAG2,ITPR1,NR4A2,NUP58,TMEM173,EHD1,SPRED1,SLC2A4,THRA,RPS6KA1,IQGAP1,IL13RA1,BCL2L1,PRKACA,ZFYVE9,CCND1,ACAP2,CDH1,SP100,CDKN1B,DAB2IP,PDE4D,IFIT1,RASGEF1A,NR2C1,MX1,SEC61B,RIPK2,FZD4,SLC11A2,ITPR3,FZD7,IRS2,JAK1,CDK19,NGFRAP1,WFS1,AXL,SLC27A1,NRG1,NR3C2,MAPK12,ARHGEF3,NKX3-1,TNRC6C,HERC5,GSTP1,FGF19,HLA-A,CXCL16,PTEN,FUT8,BAX,CD9,IGFBP2,MAPK11,ERBB3,TRIM62,SPRY2,NCOA2,RASGRF1,PDGFC,TGIF1,SHMT1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,TIMP3,PLOD2,FGFR2,RAB11FIP2,NR1D2,ACVRL1,NR4A3,GRIN2D,GPER1,CMPK2,OSR1,CPEB2,RGMA,CASP3,UGT8,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,TRIM68,SPTB,ZFYVE16,RPS6KA2,NPNT,ZCCHC12,SHC3,IL6ST,AKR1B1,RASGRP1,SP5,CYP1B1,THRB,TRIM8,USP18,EZR,PRKRA,RHEB,DPYSL3,WIPI1,MAP2,MADD,CAB39,ADIPOR1,NR2C2,PCSK5,RRAGD,PRKAA2,RUNX2,HLA-F,RASA2,CALM3,PHLPP1,IL18R1,IGF1R,COL6A1,PIM1,C10orf54,HLA-C,WNT3A,RGMB,STRADB,TCF7,PDK3,IFIT3,MAPKAPK2,GNAS,FECH,CSF1,PHLPP2,NFKBIA,SH3BP4,YOD1,LTBP2,JAK3,IFI6,RARG,COL16A1,GAS2L1,SORBS1,IL15,PSME2,TP53,PDIA5,ERBB2,IL27RA,ARHGEF16,PDGFA,ATP6V0B,TWIST1,GOT1,OAS3,PDIA6,CTDSP2,CTH,FRS3,SIRT1,TIMP2,AKT1,ERBB2IP,CD40,DUSP4,CASP4,SOCS3,DUOX1,ATP1A1,IDE,RBL1,PTK7,IRF7,SPTBN5,LIFR,ABCA1,SORT1,CPEB4,ARHGEF11,LRP4,PSMD10,GABRG2,GDF15,TGFBR1,NRP2,DNAJB9,HDAC9,IL17RB,ADRBK1,BMP7,TRIM21,KLF9,IQGAP3,SYK,MYO5A,RHOA,PSMB4,IFITM3,NR3C1,NR4A1,AMFR,PPARA,LITAF,BBS2,BCAR1,LEPR,CTSL,HLA-B,TWSG1,PLOD3,TBC1D4,ARHGEF9,ARHGEF4 |
| 1.444e-08 | -18.05 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | 175 | 43 | 17758 | 1761 |
SERPINE2,CIT,NDC80,KIF23,CALM3,CCNB1,SLC20A1,BARD1,PHLDA1,STIL,SH3KBP1,CALM2,TOP2A,UBE2T,PLCG2,FJX1,PLK4,TUBG1,TNFRSF12A,BUB1,MYBL1,HMMR,PLK1,ZWINT,CENPA,ASPM,PLAUR,CALM1,EIF5A2,PKMYT1,ANLN,KIF11,STEAP1,CDK1,PRIM1,STK17A,RBL1,DCK,ZNF367,CDCA5,CENPE,ESPL1,HOXC13 |
| 1.463e-08 | -18.04 | protein modification process | biological process | GO:0036211 | 2835 | 373 | 16441 | 1675 |
SSH1,RET,FBXO2,NRG2,PSME1,IL18,NANS,MORF4L2,CAMK1D,CCNB1,PJA2,BARD1,GRM5,CALM2,DAPK2,WEE1,PSMD1,MUC4,UBE2T,IL31RA,PALD1,PIK3CA,FUT1,CRY2,PIK3CD,MARCH2,TIPARP,MGAT5,METAP2,FBXL16,ACVR1C,PBK,LOXL2,GALNT7,ICMT,CCNF,MCFD2,RNF19B,POR,ARF4,PIAS3,PLK2,LIMK1,GNPTAB,PRDM5,NOD2,HDAC1,ITPKA,TRAF5,GAB1,CDK17,NUAK1,SOX9,HERC6,MERTK,TNFRSF19,BMP2K,RABGGTA,ATG4A,MARCH8,ZNRF2,PPP4R1,NEK2,TPST1,DAPK1,ADCK2,MAP3K9,PRKG1,OPN3,ALPK1,NCAM1,MAST4,MYLIP,NUP85,PPP6R1,SOCS5,TRAK2,GFPT1,DDB2,B3GNT7,MMD,STAT4,CALM1,ERO1A,EPHA1,ELK1,JADE2,PSMA4,RASA1,STK17A,MMP15,PTPRF,NCOA3,PRKAG2,PELI2,SETD3,CSNK1G1,AGBL5,AURKA,STK39,CDK18,MAP3K5,CFAP20,IFIH1,NRBP1,NUP58,RUSC1,EGLN1,SPRED1,MTM1,DLGAP5,GALNT12,INPP5D,RPS6KA1,TESK2,RNF182,GRK6,PRKACA,DDR1,CCND1,MUC16,RNF220,SP100,DOK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,ATG4D,SEC23A,SSH3,RIPK2,PTPN9,PRKCQ,PKMYT1,ASB13,XRCC6BP1,EPHA10,IRS2,JAK1,DDOST,CDK19,STK26,AXL,TRIOBP,TRABD2A,NRG1,MLKL,MAPK12,DCAF7,PDIA3,HERC5,CTSZ,FBXO6,PKN1,FGF19,WWP2,DTX3L,FUT2,RNF128,CTSC,ARSG,PTEN,MGAT4A,ALG13,FUT8,SGK3,WWP1,MAPK11,ERBB3,TRIM62,NCOA2,CRTAP,RASGRF1,B3GNT2,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,UBE2A,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,NEURL1B,FOS,ARSK,GALNT3,PLOD2,FGFR2,ACVRL1,DBI,PPM1H,RYK,GRIN2D,ITGAV,LRRK1,ARSB,WDR45B,MELK,UNKL,TRIM2,PPM1J,CAMKK1,CUL4B,EPHA4,MGAT5B,HDAC6,PDGFB,TRIM68,SPTB,RPS6KA2,SHC3,MKRN3,PASK,DLG1,DUSP10,PTPRE,RASGRP1,PLK1,TRIM8,ITCH,USP18,ROR1,PRKRA,CDK1,ADRBK2,STK17B,KDM4D,TRIM9,MAN2A2,MSL1,UEVLD,WIPI1,P4HA2,DOLPP1,CAB39,CPPED1,PRKAA2,LMTK3,RASA2,UBASH3B,ASB9,CALM3,ADCK5,TEC,RAB6A,B4GALT4,PHLPP1,ADAMTSL4,B4GALNT1,B3GALNT1,OTUD1,UBE2Q2,IGF1R,MDFIC,PIM1,ZRANB1,GAD1,MDFI,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,G2E3,CDK5R1,MAPKAPK2,UAP1,PLPP3,PHLPP2,KBTBD2,P4HA3,ZDHHC7,ALPK3,CTSA,YOD1,JAK3,RNF146,USP43,LMO7,IL15,P3H2,PSME2,HDAC11,CTDSPL,ERBB2,KBTBD11,PDGFA,SETDB2,ZDHHC12,PLK4,ZDHHC23,RPN2,EGLN3,LMAN1,F2R,CTDSP2,SCYL3,FRS3,CTH,SEPHS1,MAP3K3,PPIF,SIRT1,AKT1,PTPRU,CDC20,PTGER4,DUSP4,MAP3K6,SOCS3,JADE1,ATP1A1,PTPRJ,STK38,PTK7,PEX2,SPTBN5,ST3GAL1,ABCA1,MAN2B2,CMAS,PINK1,KLHL13,CIT,GNE,PSMD10,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,PPP2R3A,HDAC9,ZDHHC21,ADRBK1,CDK16,A4GALT,UBE2J1,SGK1,TRIM21,BUB1,IQGAP3,SYK,GCNT1,B3GALT6,RAB3B,PSMB4,PLAUR,AMFR,RC3H2,RUNX3,COL7A1,PELI3,MAPK8IP1,PRDX4,KLHL2,FUCA1,SERPINA1,TRIM69,SCG2,DTX4,ARRB1,OTUB2,PLOD3,CEP41,UBE2C,HIPK3 |
| 1.463e-08 | -18.04 | cellular protein modification process | biological process | GO:0006464 | 2835 | 373 | 16441 | 1675 |
SSH1,RET,FBXO2,NRG2,PSME1,IL18,NANS,MORF4L2,CAMK1D,CCNB1,PJA2,BARD1,GRM5,CALM2,DAPK2,WEE1,PSMD1,MUC4,UBE2T,IL31RA,PALD1,PIK3CA,FUT1,CRY2,PIK3CD,MARCH2,TIPARP,MGAT5,METAP2,FBXL16,ACVR1C,PBK,LOXL2,GALNT7,ICMT,CCNF,MCFD2,RNF19B,POR,ARF4,PIAS3,PLK2,LIMK1,GNPTAB,PRDM5,NOD2,HDAC1,ITPKA,TRAF5,GAB1,CDK17,NUAK1,SOX9,HERC6,MERTK,TNFRSF19,BMP2K,RABGGTA,ATG4A,MARCH8,ZNRF2,PPP4R1,NEK2,TPST1,DAPK1,ADCK2,MAP3K9,PRKG1,OPN3,ALPK1,NCAM1,MAST4,MYLIP,NUP85,PPP6R1,SOCS5,TRAK2,GFPT1,DDB2,B3GNT7,MMD,STAT4,CALM1,ERO1A,EPHA1,ELK1,JADE2,PSMA4,RASA1,STK17A,MMP15,PTPRF,NCOA3,PRKAG2,PELI2,SETD3,CSNK1G1,AGBL5,AURKA,STK39,CDK18,MAP3K5,CFAP20,IFIH1,NRBP1,NUP58,RUSC1,EGLN1,SPRED1,MTM1,DLGAP5,GALNT12,INPP5D,RPS6KA1,TESK2,RNF182,GRK6,PRKACA,DDR1,CCND1,MUC16,RNF220,SP100,DOK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,ATG4D,SEC23A,SSH3,RIPK2,PTPN9,PRKCQ,PKMYT1,ASB13,XRCC6BP1,EPHA10,IRS2,JAK1,DDOST,CDK19,STK26,AXL,TRIOBP,TRABD2A,NRG1,MLKL,MAPK12,DCAF7,PDIA3,HERC5,CTSZ,FBXO6,PKN1,FGF19,WWP2,DTX3L,FUT2,RNF128,CTSC,ARSG,PTEN,MGAT4A,ALG13,FUT8,SGK3,WWP1,MAPK11,ERBB3,TRIM62,NCOA2,CRTAP,RASGRF1,B3GNT2,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,UBE2A,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,NEURL1B,FOS,ARSK,GALNT3,PLOD2,FGFR2,ACVRL1,DBI,PPM1H,RYK,GRIN2D,ITGAV,LRRK1,ARSB,WDR45B,MELK,UNKL,TRIM2,PPM1J,CAMKK1,CUL4B,EPHA4,MGAT5B,HDAC6,PDGFB,TRIM68,SPTB,RPS6KA2,SHC3,MKRN3,PASK,DLG1,DUSP10,PTPRE,RASGRP1,PLK1,TRIM8,ITCH,USP18,ROR1,PRKRA,CDK1,ADRBK2,STK17B,KDM4D,TRIM9,MAN2A2,MSL1,UEVLD,WIPI1,P4HA2,DOLPP1,CAB39,CPPED1,PRKAA2,LMTK3,RASA2,UBASH3B,ASB9,CALM3,ADCK5,TEC,RAB6A,B4GALT4,PHLPP1,ADAMTSL4,B4GALNT1,B3GALNT1,OTUD1,UBE2Q2,IGF1R,MDFIC,PIM1,ZRANB1,GAD1,MDFI,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,G2E3,CDK5R1,MAPKAPK2,UAP1,PLPP3,PHLPP2,KBTBD2,P4HA3,ZDHHC7,ALPK3,CTSA,YOD1,JAK3,RNF146,USP43,LMO7,IL15,P3H2,PSME2,HDAC11,CTDSPL,ERBB2,KBTBD11,PDGFA,SETDB2,ZDHHC12,PLK4,ZDHHC23,RPN2,EGLN3,LMAN1,F2R,CTDSP2,SCYL3,FRS3,CTH,SEPHS1,MAP3K3,PPIF,SIRT1,AKT1,PTPRU,CDC20,PTGER4,DUSP4,MAP3K6,SOCS3,JADE1,ATP1A1,PTPRJ,STK38,PTK7,PEX2,SPTBN5,ST3GAL1,ABCA1,MAN2B2,CMAS,PINK1,KLHL13,CIT,GNE,PSMD10,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,PPP2R3A,HDAC9,ZDHHC21,ADRBK1,CDK16,A4GALT,UBE2J1,SGK1,TRIM21,BUB1,IQGAP3,SYK,GCNT1,B3GALT6,RAB3B,PSMB4,PLAUR,AMFR,RC3H2,RUNX3,COL7A1,PELI3,MAPK8IP1,PRDX4,KLHL2,FUCA1,SERPINA1,TRIM69,SCG2,DTX4,ARRB1,OTUB2,PLOD3,CEP41,UBE2C,HIPK3 |
| 1.476e-08 | -18.03 | regulation of cell death | biological process | GO:0010941 | 1498 | 218 | 16441 | 1675 |
CASP3,TXN,TRIM2,TSC22D3,DNAJC3,RET,PSME1,CAMK1D,HDAC6,BARD1,ERP29,CARD10,EPCAM,DAPK2,PSMD1,RPS6KA2,CTGF,IL6ST,SIVA1,ALDH1A3,IL31RA,MITF,PIK3CA,CTTN,SLC39A10,TIAM1,CYP1B1,PLK1,KCNIP3,ING1,ACVR1C,ITCH,CASP9,SAV1,PRKRA,SLC25A5,CDK1,POR,STK17B,ARF4,ABR,OPTN,MDK,SLC25A4,DNM1L,PLK2,MADD,NOD2,HDAC1,KLF11,UNC5B,HSPB1,TRAF5,FGD1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,SLC25A27,PHLPP1,ADAMTSL4,MERTK,LMNA,MECOM,TFAP4,IGF1R,CYR61,DAPK1,MAP3K9,SORL1,TNFRSF12A,MYDGF,PIM1,WNT3A,OXR1,ANO6,STRADB,SCRIB,ELK1,IFIT3,PSMA4,G2E3,RASA1,CDK5R1,FAS,STK17A,SEMA4D,NFKBIA,AURKA,NR4A2,STK39,CABIN1,GDF11,MAP3K5,JAK3,RARG,IFI6,XDH,SLC25A24,NQO1,THRA,INPP5D,RPS6KA1,PSME2,CAST,TP53,ERBB2,COL18A1,CD274,BCL2L1,AIFM2,PHLDA1,STIL,BCAP31,ARHGEF16,IER3,NOV,SP100,KIF14,PLCG2,BCL6,CDKN1B,DAB2IP,TWIST1,LGMN,EGLN3,CDKN2D,F2R,CHP1,CTH,SIRT1,PPIF,RIPK2,AKT1,FIGNL1,HTATIP2,PRKCQ,SLC11A2,GLO1,CD40,MAP3K6,CASP4,SOCS3,IRS2,CDK19,STK26,NGFRAP1,BHLHB9,AXL,WFS1,TLE1,NRG1,IRF7,LIFR,BIN1,GCLM,ARHGEF3,PINK1,NKX3-1,CPEB4,ARHGEF11,DAP,PDIA3,PSMD10,SELL,TGFBR1,AES,GDF15,ETS1,GSTP1,BEX2,SIX4,TOP2A,CARD8,ADORA1,CTSC,PTEN,BMP7,CST3,SGK3,TFAP2A,BAX,SGK1,PLEKHF1,TMBIM6,BUB1,ERBB3,CITED2,FAIM,SPRY2,OSGIN1,RHOA,PSMB4,RAPGEF2,PLAUR,GCLC,PIK3R1,GRIN1,PPARA,RGCC,PELI3,BCAR1,MAPK8IP1,GPLD1,FGFR2,SCG2,DHRS2,NR4A3,ARRB1,ITGAV,GPER1,SOX8,OSR1,ARHGEF9,HIPK3,MELK,ARHGEF4 |
| 1.511e-08 | -18.01 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | 194 | 46 | 17758 | 1761 |
GRN,GAA,SORT1,ARAP3,CD63,HEXB,EFHD2,FAM198B,MGST2,ARHGEF40,GSTP1,SIRPA,LMNA,ARHGEF10L,GNS,CST3,DAPK1,SGK1,RAB20,TIAM1,NAGA,LAMP2,CPD,ALDH2,MCTP1,TIMP2,ERMAP,MPP1,PLAUR,DOCK5,CRISPLD2,GABARAPL1,ALDH3B1,SCARB2,MID1IP1,RBM47,HPSE,ZDHHC7,ARRB1,GLA,REEP4,NDFIP1,SLC27A3,CPPED1,RRAGD,PCSK5 |
| 1.580e-08 | -17.96 | cell leading edge | cellular component | GO:0031252 | 346 | 69 | 17570 | 1756 |
MTM1,NF2,SSH1,S100A11,IQGAP1,HDAC6,APC2,EPS8L2,CDH1,PIK3CA,TUBG1,CTTN,TLN2,PACSIN1,SCYL3,SGCE,SYNE2,EZR,DAG1,ARF4,ARHGEF26,GABARAPL1,DPYSL3,PLCG1,PTPRJ,CORO1C,NRG1,PIEZO1,ARF6,COBL,FGD1,DDX58,WASF3,ARAP3,PACSIN2,CIT,EPS8,GABRG2,NCKAP1,CNTNAP2,ADORA1,RINL,TNFRSF12A,SPRY2,MYO5A,CCDC88A,S100A6,EPB41L5,RHOA,GRIN1,SPATA13,SCRIB,AIF1L,BCAR1,ANTXR1,STX3,RASA1,FRMD4B,RASGRP2,KLHL2,GNAS,PLEKHH2,SWAP70,FGD6,GPER1,ITGAV,ARPC2,NRBP1,ARHGEF4 |
| 1.612e-08 | -17.94 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15944 | 1640 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,KLC3,ZFAND4,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,GPR161,SOCS5,TRAK2,GFPT1,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,ARF6,GAB1,E2F8,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,NR3C1,AMFR,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,SERPINA1,FAT4,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.688e-08 | -17.90 | GROSS_HYPOXIA_VIA_ELK3_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_UP | 201 | 47 | 17758 | 1761 |
ARHGAP11A,CASP3,SSH1,HOXB7,CPT2,DDIT4L,NDC80,ARL4C,PLXNA1,CCNB1,LGALS3BP,SAC3D1,CDKN2C,CCND1,GATA2,DOK4,AOX1,TRIM21,MINPP1,SLC12A2,F2R,SEPHS1,AMOTL2,HES1,CENPA,TIMP2,KIF20A,PBK,MGAT4B,CBX6,KIF1C,TNS1,GNA11,FAS,PIAS3,AXL,CORO1C,CSF1,CDCA5,DBI,ARRB1,EFNA5,NDE1,CCNB2,UBE2C,ABCG1,EGLN1 |
| 1.691e-08 | -17.90 | DURAND_STROMA_S_UP | MSigDB lists | DURAND_STROMA_S_UP | 280 | 59 | 17758 | 1761 |
NCKAP5,CDKN1C,IL15,UBASH3B,TSC22D3,MORC4,NDRG2,IL13RA1,SLC1A3,SEPP1,FBLN1,SRPX2,TSPAN7,B4GALNT1,DTX3L,B3GALNT1,TSPAN6,A4GALT,FUT8,TFAP2A,TRIM21,RTKN2,IFIT1,PDE4D,LGMN,NCAM1,LRP11,SULF2,CYP26B1,ADAMTS2,COL6A2,LONRF3,CAPN6,SLC39A8,CORO2A,OXR1,PYGO1,ZNF618,DPYSL3,EPN3,PTPRF,MMP15,FAT4,SLC4A4,POPDC3,FGFR2,MATN2,INPP4B,ARRB1,EFNA5,CDK18,HOXB13,LTBP2,SERPINB1,ST3GAL1,SLC27A3,JAK3,AHR,RAB3IL1 |
| 1.742e-08 | -17.87 | cell projection morphogenesis | biological process | GO:0048858 | 947 | 150 | 16441 | 1675 |
MYL9,EMX1,UGT8,AK7,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,RPS6KA2,PSMD1,LRRC6,SHC3,DPYSL2,DLG1,TRPC1,NTN4,MYH14,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,EZR,DZIP1L,DPYSL3,PLCG1,MAP2,LIMK1,TRAF3IP1,UNC5B,MYL12B,SCN5A,RASA2,RAB23,CALM3,IGF1R,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,DPYSL5,RGMB,CALM1,EPHA1,NPHP3,RANBP9,NFIB,PSMA4,RASA1,CDK5R1,ONECUT1,SEMA4D,MATN2,AURKA,PITPNA,NR4A2,CFAP20,ARPC2,JAK3,SEMA3A,KLF7,EHD1,SPRED1,TCTN2,PSME2,RPS6KA1,IQGAP1,C5orf30,ERBB2,STIL,TTC21B,PDGFA,ARTN,DACT1,DAB2IP,EPHB4,RASGEF1A,DLG3,SNX10,ETV4,FRS3,SEMA3B,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,CEP162,IRS2,EPHA10,JAK1,SLC9A6,SPTBN5,EFNA5,NRG1,LIFR,COBL,TTC8,COL9A3,PACSIN2,ARHGEF11,POC1B,LRP4,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,NEO1,KIF5B,PTEN,BMP7,SGK1,ERBB3,S100A6,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,CFAP46,FMN1,RAPGEF2,GRIN1,YES1,BBS2,CNTNAP1,FGFR2,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,CEP41,L1CAM,RGMA |
| 1.804e-08 | -17.83 | PROVENZANI_METASTASIS_DN | MSigDB lists | PROVENZANI_METASTASIS_DN | 134 | 36 | 17758 | 1761 |
EPAS1,S100A11,ST14,BLVRB,CTDSPL,SDC4,ARL4C,GRK6,TRIB2,S100A2,ANO1,TSEN34,CCND1,RCN1,BMP7,TACSTD2,PDE4D,PDIA6,NFE2L3,PDGFC,TIMP2,TNIP1,IFITM3,FOXJ2,AK4,KLK6,YES1,F12,WIPI1,DHRS2,P4HA2,SPINT2,NMI,PLOD3,HSPB1,TBC1D4 |
| 1.892e-08 | -17.78 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | 221 | 50 | 17758 | 1761 |
ILDR1,AVPI1,KLHL13,TMEM41B,COL4A5,F11R,FBXO6,TRIB2,FAM101B,SIRPA,LMNA,TOP2A,LYPD3,VASN,RRBP1,NEK2,CD9,KLC3,RP2,CTTN,IQGAP3,PTPRE,OSGIN1,GPX4,HES1,PRSS23,GUSB,CDC20,C3orf52,IGSF8,C15orf39,ITPR3,ALCAM,MAPK8IP1,RPL12,SHROOM3,RND3,DCK,CORO1C,LIMK1,CDCA5,SECTM1,FAM110C,RELL1,EPB41L4A,PLIN3,ARF6,NRGN,RARG,SNX30 |
| 1.902e-08 | -17.78 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 2797 | 368 | 16441 | 1675 |
TXN,LGR4,DNAJC3,HEXB,RET,NRG2,PSME1,IL18,MORF4L2,CAMK1D,CCNB1,BARD1,CARD10,GRM5,CALM2,PSMD1,CTGF,ZFP36,IL31RA,FOSB,PIK3CA,IRF2,PIK3CD,TIPARP,SMARCA2,TNIP1,ACVR1C,CASP9,TFAP2C,PRKAR2B,F12,LDB2,SAV1,RNF19B,ARF4,AHRR,PIAS3,PLCG1,ANKRD6,PLK2,NKD1,NOD2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,GAB1,HOXC13,DDX58,CDKN1C,GGA1,ITGA6,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,ITGA3,CYR61,NEK2,DAPK1,MAP3K9,SORL1,MYDGF,NCAM1,MYLIP,NUP85,RIMS2,SOCS5,MMD,MFI2,SALL4,STAT4,CALM1,PYM1,MYBL2,ELK1,TP53INP2,PSMA4,NFIB,RASA1,FAS,NCOA3,PRKAG2,ETS2,SEMA4D,PELI2,SETD3,AURKA,NR4A2,STK39,GDF11,MAP3K5,TMEM173,XDH,SPRED1,ARMCX3,GRHL2,DLGAP5,THRA,RPS6KA1,IQGAP1,PRKACA,APC2,CCND1,ST5,CDH1,SP100,DACT1,CDKN1B,DAB2IP,RASGEF1A,ETV4,MYT1,MED30,RIPK2,FZD4,FOXJ2,CDCA2,PRKCQ,SLC11A2,PYGO1,GTF2A2,FZD7,NFIX,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,SLC27A1,KLF5,NRG1,MAPK12,PCOLCE,TNRC6C,NKX3-1,CKAP2,SDC4,PBX3,PKN1,ETS1,FGF19,TEAD3,SIX4,WWP2,E2F7,ITGB8,RNF128,CTSC,PTEN,CST3,BAX,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,NCOA2,RASGRF1,PDGFC,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,FURIN,YES1,FOS,GPLD1,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,RYK,GRIN2D,GPER1,CENPE,HMGA1,LRRK1,FZD5,OSR1,USF2,ESPL1,RGMA,JARID2,CASP3,EPAS1,CNOT8,CAMKK1,CUL4B,EPHA4,ARFGEF1,NENF,HDAC6,PDGFB,ERP29,SPTB,FANCI,EPCAM,RPS6KA2,HSF2,GRHL1,NPNT,SHC3,IL6ST,ELF5,PASK,MITF,DLG1,SLC39A10,MYBL1,RASGRP1,ZNF462,PLK1,THRB,PCGF5,TRIM8,CITED4,ITCH,NFE2L1,EZR,CDK1,KDM4D,MDK,GPRC5B,KLF12,MADD,PRKCDBP,CAB39,MAFF,NR2C2,RUNX2,BVES,RASA2,DNAJB2,ETV5,ASB9,CALM3,TEC,FBLN1,DAZAP1,IGF1R,GATA2,SUCO,MDFIC,PIM1,WNT3A,CCDC88A,MDFI,ELK3,RGMB,STRADB,PDE5A,SCRIB,CDK5R1,BCAR3,MAPKAPK2,NUDT16,ONECUT1,PLPP3,CSF1,NFKBIA,NLRC5,JAK3,TOB1,RARG,KLF7,PROM2,SORBS1,AVPI1,UPF3B,IL15,FOXM1,PSME2,TP53,ERBB2,OSR2,LPIN3,EMP2,STIL,BCAP31,IER3,PDGFA,SS18,LMO4,KIF14,PLCG2,BCL6,CDH3,TWIST1,ECE1,EPB41L4B,NOTCH3,EGLN3,F2R,DVL2,FRS3,CTH,CHP1,MAP3K3,SIRT1,TIMP2,AKT1,CDC20,SERTAD3,ERBB2IP,CD40,MAP3K6,JADE1,RBL1,TLE1,IRF7,SPTBN5,EFNA5,GLIS3,ANXA3,PINK1,CD63,ARHGEF11,DAP,PSMD10,TGFBR1,HMGN3,GDF15,TRIB2,PARM1,PPP2R3A,IRF2BPL,TOP2A,CARD8,ADORA1,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,IQGAP3,SYK,NFE2L3,HES1,RHOA,PSMB4,NR3C1,PLAUR,NR4A1,GCLC,RGCC,PPARA,PRICKLE1,MAML2,RUNX3,BANK1,RAP2C,NMI,ARRB1,PPP2R3C,ZMIZ1,SOX8,NDFIP1,UBE2C,AHR |
| 1.995e-08 | -17.73 | KONG_E2F3_TARGETS | MSigDB lists | KONG_E2F3_TARGETS | 95 | 29 | 17758 | 1761 |
HMMR,PLK1,SPC25,KIF20A,DEPDC1,DLGAP5,FIGNL1,PBK,CDC20,NUSAP1,NUF2,CCNF,CCNB1,KIF11,PSIP1,PRIM1,TOP2A,FAM111A,RPL12,UBE2T,RBL1,DCK,CDCA5,AURKA,BUB1,IQGAP3,NCAPG2,UBE2C,MELK |
| 2.004e-08 | -17.73 | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 261 | 56 | 17758 | 1761 |
ARHGEF3,GRHL2,IGFBP6,ST14,FXYD3,ESRP1,SOX9,HDAC11,SDC4,FHDC1,CYB561,ISYNA1,SDC1,DDR1,ANO1,FZD6,EPCAM,SESN3,RNF128,CDH1,CALD1,VASN,ELF5,CD9,BCL6,POF1B,SLC44A2,CLDN4,TNFRSF12A,IGFBP2,TACSTD2,EPB41L4B,ERBB3,F2R,TGIF1,SAT1,EZR,TFAP2C,COL7A1,FOS,DPYSL3,MDK,GALNT3,PIAS3,ATP1A1,RND3,SHROOM3,NGFRAP1,FGFR2,KCNK1,PLK2,SPINT2,ZNF704,COL16A1,OCLN,PROM2 |
| 2.040e-08 | -17.71 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | 215 | 49 | 17758 | 1761 |
DDX58,NFKBIE,IL15,DNAJC3,SDC4,TAP1,SLC7A2,DSE,ETS1,HDAC9,TMCC3,NOV,CXCL16,ITGB8,LYPD3,DRAM1,ANKRD12,SGK1,RFX5,IFIT1,MAST4,AMOTL2,DOCK4,RIPK2,TNIP1,CITED4,GCLC,PLAUR,USP18,NUB1,C3orf52,IFIT3,C15orf39,RNF19B,FRMD4B,CD83,SOCS3,NFKBIA,SLC2A6,RAB11FIP1,CLIP4,ZNF165,NFKBIZ,CMPK2,SERPINB1,IFIH1,MAFF,OCLN,EHD1 |
| 2.063e-08 | -17.70 | regulation of cell proliferation | biological process | GO:0042127 | 1479 | 215 | 16441 | 1675 |
EMX1,CASP3,CNOT8,FBXO2,NDRG2,IL18,TP53I11,CCNB1,VASH1,PDGFB,LTBP3,CDKN2C,EPCAM,BTG3,RPS6KA2,CTGF,IL6ST,IL31RA,MITF,DLG1,AKR1B1,TACSTD2,SLC39A10,S100A13,CYP1B1,SMARCA2,CD55,ING1,ACVR1C,ITCH,TFAP2C,ICMT,SAV1,PRKRA,SLC25A5,SESN1,POR,OPTN,PGF,HPSE,NOD2,HDAC1,KLF11,SP6,TRAF5,CAPN1,GRN,SCN5A,RUNX2,CDKN1C,SERPINE2,LGALS3,NUAK1,HLA-E,SOX9,ETV5,SLC25A27,TEC,FBLN1,MECOM,TFAP4,C9orf69,TNS3,IGF1R,CYR61,GATA2,MYDGF,C10orf54,WNT3A,CCDC88A,MFI2,PDE5A,EIF2AK1,EPHA1,IFIT3,NFIB,STX3,FAS,NUDT16,NCOA3,CSF1,CGREF1,NFKBIA,SH3BP4,CLMN,EGFL7,GDF11,JAK3,TOB1,RARG,XDH,PLA2G4A,NF2,FOXM1,S100A11,IL15,INPP5D,P3H2,TP53,ERBB2,PKP2,COL18A1,FTH1,OSR2,CD274,BCL2L1,PRKACA,EMP2,TNFSF9,PDGFA,CCND1,NOV,KIF14,FABP6,BCL6,CDKN1B,CDH3,DAB2IP,TWIST1,RTKN2,EPB41L4B,PDE4D,NOTCH3,EGLN3,DLG3,CDKN2D,F2R,ETV4,DVL2,SIRT1,TIMP2,RIPK2,AKT1,PTPRU,SAT1,CDC20,PRKCQ,CD40,FZD7,IRS2,PTPRJ,JAK1,PEX2,OVOL1,NRG1,LIFR,CTHRC1,NKX3-1,IGFBP6,ADGRG1,TGFBR1,PKN1,ETS1,GSTP1,EFNB1,FGF19,SIX4,HLA-A,NRP2,CD109,CTNNBIP1,E2F7,ADORA1,PTEN,BMP7,CST3,SGK3,TFAP2A,BAX,CD9,SGK1,IGFBP2,MAPK11,KLF9,ERBB3,CNOT6L,IQGAP3,SYK,SPRY2,S100A6,HES1,PDGFC,TGIF1,RHOA,ASPM,RAPGEF2,NR4A1,EIF5A2,UBE2A,RGCC,RUNX3,YES1,GPLD1,PRDX4,FGFR2,SCG2,ACVRL1,DHRS2,CDCA7L,CTSV,TBX18,NR4A3,ITGAV,GPER1,HMGA1,SOX8,ICOSLG,OSR1,FZD5,ZMIZ1,NDFIP1,PTGES,AHR,CD33,JARID2 |
| 2.118e-08 | -17.67 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16720 | 1701 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,RNF224,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.118e-08 | -17.67 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | 196 | 46 | 17758 | 1761 |
GRN,GAA,LGALS3,BLVRB,HEXB,ASAH1,KCTD12,IL13RA1,DSE,ARHGEF40,SIRPA,APLP2,ATP6V0B,TNS3,PLCG2,CST3,DAPK1,SNX10,NAGA,SYK,GM2A,CKAP4,CYP1B1,GCA,ALDH2,TIMP2,MPP1,PLAUR,C15orf39,RNPEP,ADRBK2,TP53I3,CRISPLD2,TMEM164,ALDH3B1,RBM47,SERPINA1,CORO1C,SLC2A6,SECTM1,ZDHHC7,CLMN,CTSA,GLA,PLIN3,SLC27A3 |
| 2.144e-08 | -17.66 | cytoskeletal protein binding | molecular function | GO:0008092 | 804 | 131 | 16491 | 1673 |
MYL9,SSH1,ADD1,ARFGEF1,HDAC6,FAM101B,SPTB,PLS3,CALM2,STIM1,DPYSL2,DLG1,POF1B,RP2,MYH14,PACSIN1,TLN2,RCAN3,MYRIP,NEB,PLK1,KIFC2,SNTB2,EZR,KIF13A,TNS1,ANLN,MAP2,TRAF3IP1,FAM110C,NOD2,TMOD2,EPB41L4A,MYL12B,CAPN1,LASP1,PIFO,SCN5A,CALM3,KIF23,RAB6A,KIF13B,TBCD,FXYD5,LIMCH1,CACNA1D,MYLIP,CCDC88A,EPB41L5,DPYSL5,KIF20A,CORO2A,CALM1,VEZT,ANTXR1,AP1AR,PLEKHH2,FAM83D,AGBL5,CLMN,NDE1,ARPC2,SHROOM2,HOOK1,AFAP1,RUSC1,GAS2L1,SORBS1,NF2,TMSB15A,APC2,TMSB15B,EPS8L2,SCNN1A,CDH1,KIF14,REEP1,DIXDC1,ESPN,EPB41L4B,RAB27B,CHP1,MYO5B,CAMSAP3,SSH3,CAPN6,S100A4,SYNE2,UTRN,KIF1C,NUSAP1,DAG1,GABARAPL1,ATP1A1,PDLIM3,SHROOM3,CORO1C,TRIOBP,SPTBN5,RGS14,REEP4,COBL,BIN1,FBLIM1,WASF3,PACSIN2,EPS8,ARL4C,SNTA1,KIF5B,ADD3,CALD1,KLC3,IQGAP3,CLIP2,MYO5A,S100A6,FARP2,SUN2,RAB3B,RHOA,FMN1,SYBU,DIAPH2,STMN3,AIF1L,SNTB1,KIF11,MAPK8IP1,KLHL2,CENPE |
| 2.145e-08 | -17.66 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 171 | 42 | 17758 | 1761 |
AVPI1,GDF15,PHLDA1,IER3,AKIRIN1,WEE1,CTGF,CYR61,LYPD3,GATA2,FLRT3,ZFP36,FOSB,DUSP10,SGK1,CLDN4,TNFRSF12A,CTTN,EGLN3,TIPARP,ZNF365,CTH,SEMA3B,HES1,NR4A1,PLAUR,CASP9,C3orf52,SERTAD3,EZR,DUSP4,ZFAND5,FOS,IRS2,SLCO4A1,ETS2,KBTBD2,NR4A3,NR4A2,GEM,F2RL1,MAFF |
| 2.193e-08 | -17.64 | KIM_WT1_TARGETS_UP | MSigDB lists | KIM_WT1_TARGETS_UP | 209 | 48 | 17758 | 1761 |
CCNE2,CDK17,NFKBIE,ENO2,SOX9,SDC4,SLC20A1,ETS1,CARD10,IER3,PDGFA,RAB15,TNS3,CA2,CYR61,CALD1,MAP3K9,SGK1,TNFRSF12A,KLF9,TIAM1,PTPRE,ZNF365,SPRY2,ATP2B1,ARAP2,MBP,B3GNT2,NR3C1,NR4A1,PLAUR,C3orf52,LITAF,TNS1,ATP1B1,CD83,TIMP3,RND3,KCNK1,CSF1,PHLPP2,NFKBIA,HMGA1,GEM,ZMIZ1,ST3GAL1,MAFF,COBL |
| 2.199e-08 | -17.63 | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | 90 | 28 | 17758 | 1761 |
HMMR,PLK1,LGALS3,SPC25,KIF20A,FIGNL1,ASPM,PBK,CDC20,CDCA8,NUSAP1,NUF2,VARS2,CCNB1,CDK1,RASGRP2,IL17RB,BMP7,CDCA5,ABCB1,NEK2,AURKA,BUB1,CENPE,CMPK2,NCAPG2,CCNB2,ACOT7 |
| 2.229e-08 | -17.62 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 135 | 36 | 17758 | 1761 |
SLC35D2,NQO1,ESRP1,ITGA6,PDIA5,PDIA3,F11R,SH2D4A,SYTL2,PDIA4,MESDC2,MECOM,EPCAM,CA2,RNF128,LLGL2,DOK4,ATP8B1,ERBB3,EPHB4,CPD,ACBD5,GFPT1,C3orf52,ATP1B1,GALNT7,GRTP1,GALNT3,KCNK1,VSIG10,KLF5,STK39,SH3BGRL2,MAL2,SYT13,FZD5 |
| 2.237e-08 | -17.62 | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 112 | 32 | 17758 | 1761 |
PLA2G4A,TRIM2,LRP4,SOX9,LMCD1,DNER,CDH1,LMO4,ALDH1A3,BCL6,WWP1,IGFBP2,KLF9,TSPAN1,EGLN3,CYP1B1,LAMP2,PDGFC,SLC39A8,CYS1,TFAP2C,SESN1,STK17B,MAP3K6,FZD7,ARHGEF26,ATP1A1,PDLIM3,FGFR2,TLE1,LRRK1,MAFF |
| 2.237e-08 | -17.62 | MODULE_397 | MSigDB lists | MODULE_397 | 112 | 32 | 17758 | 1761 |
ARHGAP11A,IGFBP6,HOXB7,FOXM1,TBC1D1,PTTG1,NDC80,KIF23,NUF2,GPSM2,ARHGEF16,SAC3D1,ZNF432,PLK4,ALDH7A1,EPHB4,DVL2,IGSF3,PLK1,CDC20,MYBL2,MBNL3,OGDHL,KIF11,CDCA7L,CDCA5,AURKA,DONSON,CABIN1,CENPE,AFAP1,RUSC1 |
| 2.242e-08 | -17.61 | GSE7852_THYMUS_VS_FAT_TREG_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_DN | 190 | 45 | 17758 | 1761 |
CD99,IER5L,SORBS1,RUNX2,NFKBIE,IL15RA,ST14,DNAJB2,INPP5D,ASAH1,NCKAP1,PHLDA1,TNFSF9,BMP2K,IER3,PLS3,APOBEC3B,FAM46A,DRAM1,GOT1,TSPAN13,TIPARP,GM2A,ENPP4,RGMB,ADCK3,FZD4,S100A4,MRS2,FOXL1,HLF,NR1D2,FAM114A1,ABCB1,PCDH19,ARRB1,SP6,PLD1,ITGAV,UNC5B,EPB41L4A,FZD5,ARSB,MAFF,CBX7 |
| 2.255e-08 | -17.61 | HALLMARK_APOPTOSIS | MSigDB lists | HALLMARK_APOPTOSIS | 159 | 40 | 17758 | 1761 |
CASP3,BMF,ADD1,ENO2,LGALS3,IGFBP6,DAP,DNAJC3,TAP1,ERBB2,IL18,BCL2L1,SLC20A1,BCAP31,LMNA,IER3,TOP2A,CCND1,WEE1,BTG3,BAX,CDKN1B,TNFRSF12A,ERBB3,F2R,PLCB2,CTH,GPX4,TIMP2,IFITM3,CASP9,SAT1,CASP4,FAS,TIMP3,H1F0,DNM1L,MADD,AIFM3,HSPB1 |
| 2.470e-08 | -17.52 | GSE2706_2H_VS_8H_R848_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_UP | 178 | 43 | 17758 | 1761 |
MAN2B2,SIGIRR,SORT1,PINK1,ATP8A1,ZCCHC24,BLVRB,SDC4,IER3,ARHGEF10L,CTSC,SLC16A6,SIVA1,FXYD5,ADAM15,SGK1,AHCY,TECR,ALDH3A2,TPCN1,CRTAP,CYP1B1,TIMP2,PQLC3,MPP1,CDA,ERBB2IP,PDK3,NPC2,CRISPLD2,SCRN2,AHRR,DUOX1,ALDH5A1,ACADSB,RAP2C,GEM,MAP3K5,NRGN,RARG,CBX7,MAFF,ABCG1 |
| 2.586e-08 | -17.47 | GNF2_BUB1 | MSigDB lists | GNF2_BUB1 | 26 | 14 | 17758 | 1761 |
HMMR,PLK1,KIF20A,FOXM1,ASPM,CDC20,RANBP1,NDC80,CDCA8,BUB1,CENPE,CCNB2,ESPL1,MELK |
| 2.655e-08 | -17.44 | PEREZ_TP53_AND_TP63_TARGETS | MSigDB lists | PEREZ_TP53_AND_TP63_TARGETS | 191 | 45 | 17758 | 1761 |
COL9A3,TNRC6C,CDKN1C,NUAK1,ZCCHC24,TSC22D3,RET,COL18A1,SEPP1,DHRS3,APC2,FAM46C,TMEM63A,SUSD2,SIPA1L2,IGF1R,FRY,DOK4,VASN,REEP1,CNNM4,EPB41L4B,C10orf54,NOTCH3,ULBP2,MYLIP,RASGRP1,MX1,KCNJ12,TRIM8,LONRF3,TACC1,SPATA13,GRTP1,GNA11,CRISPLD2,PGF,HS6ST1,PTPRJ,SEMA4D,RAB11FIP1,ARRB1,SOX8,UNC5B,PCSK5 |
| 2.687e-08 | -17.43 | regulation of cellular component organization | biological process | GO:0051128 | 2113 | 289 | 16441 | 1675 |
SSH1,ADD1,ATP8A1,HEXB,RET,PLXNA1,CAMK1D,CCNB1,NCS1,CDKN2C,CTGF,TACSTD2,SEMA3G,PACSIN1,TIAM1,SMARCA2,CDA,NBPF3,PIF1,CCNF,SLC25A5,ABR,ENPP1,MID1IP1,DNM1L,PLK2,LIMK1,TRAF3IP1,FAM110C,NOD2,TMOD2,ITPKA,ARF6,F2RL1,LZTS1,FGD1,SEMA6B,TBC1D1,SOX9,FAM21C,MERTK,LMNA,ITGA3,CYR61,MEGF8,FLRT3,VASN,NEK2,SORL1,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,MFI2,ANO6,PIP4K2C,EPHA1,STX3,RASA1,FAS,PTPRF,AP1AR,PLEKHH2,SEMA4D,CSNK1G1,FGD6,AURKA,ARPC2,ADAMTS16,EHD1,MTM1,FOXO6,DLGAP5,THRA,RPS6KA1,PTTG1,PKP2,BCL2L1,PRKACA,APC2,DDR1,MNS1,EPS8L2,NOV,CDKN1B,DAB2IP,ACSL4,TSPAN1,CDKN2D,SEMA3B,CAMSAP3,SSH3,CAPN6,PRKCQ,NUSAP1,PKMYT1,SNX12,PPP2R5A,SHROOM3,CORO1C,AXL,SIPA1L1,TRIOBP,KLF5,NRG1,COBL,WASF3,TCAF1,IGFBP6,CKAP2,EPS8,SDC4,ETS1,SRPX2,ADGRB2,SIX4,CTNNBIP1,CXCL16,IGSF9,PTEN,CST3,FAM20B,SGK3,BAX,ATP8B1,ADAM15,IGFBP2,CNOT6L,SPRY2,TRIM62,OSGIN1,FARP2,FMN1,RAPGEF2,PIK3R1,EIF5A2,GRIN1,KIF11,FGFR2,ACVRL1,ITGAV,GPER1,CENPE,HMGA1,FHL1,FZD5,ARSB,ESPL1,JARID2,EPHA4,ARFGEF1,F11R,HDAC6,SDC1,PDGFB,SPTB,SH3KBP1,ZFYVE16,RPS6KA2,DPYSL2,SIVA1,MITF,DLG1,RAB20,CTTN,MYH14,S100A13,NEB,PLK1,ING1,STRIP2,ITCH,EZR,KLK6,ANLN,DPYSL3,TRIM9,ARHGEF19,GPRC5B,ADIPOR1,PIEZO1,RAP1GAP,MYL12B,GRN,PIFO,BMF,ARAP3,LGALS3,HJURP,SERPINE2,BVES,DNAJB2,ETV5,NCKAP1,FBLN1,IGF1R,GATA2,KIF13B,TBCD,WNT3A,ZRANB1,CCDC88A,NUBP1,CDK5R1,RASGRP2,TMEM30A,ITGA7,CGREF1,CDCA5,SH3BP4,PLD1,SHROOM2,SEMA3A,AFAP1,COL16A1,PROM2,GAS2L1,LZTFL1,SORBS1,NF2,FOXM1,TP53,ERBB2,ARHGEF16,IER3,PDGFA,KIF14,LMO4,PLCG2,PLK4,BCL6,VAT1,ESPN,TWIST1,DIXDC1,LMAN1,CHP1,PPIF,SIRT1,AKT1,CDC20,SERTAD3,PTGER4,DAG1,ARHGAP35,JADE1,IDE,PTPRJ,BHLHB9,PTK7,SPTBN5,EFNA5,BIN1,FBLIM1,PACSIN2,PINK1,ARHGEF11,CD63,CIT,LRP4,PSMD10,GDF15,TGFBR1,CRABP2,IL17RB,KIF5B,BMP7,KIAA0319,GTF2F2,SGK1,BUB1,SYK,MYO5A,HES1,RHOA,FBLN5,PLAUR,RGCC,STMN3,BORA,BCAR1,ARHGAP24,SWAP70,CTSV,ARRB1,UBE2C,TBC1D4,L1CAM,AHR |
| 2.710e-08 | -17.42 | MODULE_5 | MSigDB lists | MODULE_5 | 425 | 79 | 17758 | 1761 |
MYL9,BCAM,HSPG2,EPAS1,S100A11,RPS6KA1,TAP1,CACNA2D2,IL13RA1,SDC1,EMP2,IER3,CCND1,EPCAM,TYMP,SCNN1A,TACSTD2,NOTCH3,LGMN,TSPAN1,LAMP3,CYP1B1,MX1,CD55,COL6A2,TIMP2,SLC39A8,S100A4,CDA,ARHGDIB,ITPR3,LDB2,ALCAM,CASP4,SOCS3,DPYSL3,WFS1,P4HA2,SECTM1,PIK3C2B,NRGN,MAFF,GRN,ANXA3,PCOLCE,IGFBP6,ITGA6,BLVRB,SELL,ASAH1,SEPP1,DHRS3,FBLN1,TSPAN7,GNS,ITGA3,CYR61,GATA2,CTSC,CALD1,COL6A1,PPP4R1,PIM1,CITED2,HES1,PLSCR1,NR4A1,PLAUR,CYB5A,FUCA1,TIMP3,SERPINA1,ETS2,ITPR1,DTX4,TCEAL4,CTSA,LTBP2,SERPINB1 |
| 2.748e-08 | -17.41 | kidney-Wilms_tumour | COSMIC cancer mutations | kidney-Wilms_tumour | 561 | 97 | 17775 | 1757 |
KIAA1462,PPM1J,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,SS18,WEE1,RPS6KA2,CDH1,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PTGER4,PRKCQ,ROR1,PKMYT1,IDH1,SLC25A5,MAP3K6,STK17B,ADRBK2,CXXC4,EPHA10,PLCH1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ZNF432,ADRBK1,IGF1R,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,ADCK3,TESK1,AMER1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,PER3,JAK3,HIPK3,NRBP1,MELK |
| 2.817e-08 | -17.38 | MODULE_18 | MSigDB lists | MODULE_18 | 440 | 81 | 17758 | 1761 |
TRIM2,DLGAP5,NQO1,EPAS1,FOXM1,S100A11,PTTG1,C5orf30,NRG2,CCNB1,SDC1,EMP2,CARD10,IER3,APOBEC3B,CDKN2C,BTG3,ALDH1A3,VAT1,IFIT1,CKS2,PLK1,LAMP2,SEC23A,SGCE,CENPA,TIMP2,PTPN9,S100A4,CDC20,CDA,HTATIP2,PKMYT1,DUSP4,ICMT,ITPR3,CCNF,CDK1,ATP1A1,AGPAT2,PLK2,BMP1,GCLM,COL9A3,PCOLCE,CDKN1C,ITGA6,EPS8,ETV5,GDF15,TRIB2,DHRS3,HOXB2,PDIA4,M6PR,TOP2A,ITGA3,CTSC,TFAP2A,AHCY,ERBB3,GPR161,IGSF3,TGIF1,ZWINT,PRSS23,PLSCR1,LPGAT1,TCF7,GGH,KIF11,PSMA4,CDK5R1,TIMP3,RND3,PLOD2,UBE2C,SHROOM2,ESPL1,ACOT7,JARID2 |
| 2.827e-08 | -17.38 | WHITEFORD_PEDIATRIC_CANCER_MARKERS | MSigDB lists | WHITEFORD_PEDIATRIC_CANCER_MARKERS | 113 | 32 | 17758 | 1761 |
DLGAP5,CKAP2,PTTG1,CDCA8,NUF2,CCNB1,CENPN,TOP2A,KIF14,PLK4,NEK2,TWIST1,BUB1,CKS2,CENPA,ZWINT,PBK,MYBL2,CCDC34,GGH,CDCA2,NUSAP1,KIF11,CDK1,ZNF367,CDCA5,AURKA,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 2.874e-08 | -17.36 | chemotaxis | biological process | GO:0006935 | 789 | 129 | 16441 | 1675 |
MYL9,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,CMTM6,SPTB,CALM2,TYMP,PSMD1,RPS6KA2,SHC3,ELMO2,DPYSL2,DLG1,TRPC1,NTN4,MYH14,SEMA3G,PIK3CD,TIAM1,RASGRP1,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,MYL12B,SEMA6B,SCN5A,LGALS3,RASA2,CALM3,CYR61,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,NUP85,DPYSL5,RGMB,CALM1,ANO6,SCRIB,EPHA1,PSMA4,NFIB,RANBP9,CDK5R1,RASA1,SEMA4D,MATN2,PITPNA,PLD1,ARPC2,JAK3,SEMA3A,KLF7,SPRED1,PSME2,RALBP1,RPS6KA1,ERBB2,ARHGEF16,PDGFA,NOV,ARTN,DAB2IP,EPHB4,PDE4D,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,DOCK4,COL6A2,PRKCQ,ALCAM,DAG1,MYL12A,CMTM7,ARHGAP35,EPHA10,IRS2,PTPRJ,JAK1,NRG1,SPTBN5,EFNA5,CMTM4,COL9A3,ARHGEF11,PSMD10,COL4A5,EFNB1,FGF19,NRP2,NEO1,KIF5B,CXCL16,BMP7,ERBB3,SYK,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,PLAUR,RAPGEF2,NR4A1,GRIN1,YES1,BCAR1,CNTNAP1,SCG2,FGFR2,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,RGMA |
| 2.874e-08 | -17.36 | taxis | biological process | GO:0042330 | 789 | 129 | 16441 | 1675 |
MYL9,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,CMTM6,SPTB,CALM2,TYMP,PSMD1,RPS6KA2,SHC3,ELMO2,DPYSL2,DLG1,TRPC1,NTN4,MYH14,SEMA3G,PIK3CD,TIAM1,RASGRP1,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,MYL12B,SEMA6B,SCN5A,LGALS3,RASA2,CALM3,CYR61,FLRT3,COL6A1,CACNA1D,NCAM1,WNT3A,NUP85,DPYSL5,RGMB,CALM1,ANO6,SCRIB,EPHA1,PSMA4,NFIB,RANBP9,CDK5R1,RASA1,SEMA4D,MATN2,PITPNA,PLD1,ARPC2,JAK3,SEMA3A,KLF7,SPRED1,PSME2,RALBP1,RPS6KA1,ERBB2,ARHGEF16,PDGFA,NOV,ARTN,DAB2IP,EPHB4,PDE4D,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,DOCK4,COL6A2,PRKCQ,ALCAM,DAG1,MYL12A,CMTM7,ARHGAP35,EPHA10,IRS2,PTPRJ,JAK1,NRG1,SPTBN5,EFNA5,CMTM4,COL9A3,ARHGEF11,PSMD10,COL4A5,FGF19,EFNB1,NRP2,NEO1,KIF5B,CXCL16,BMP7,ERBB3,SYK,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,PLAUR,RAPGEF2,NR4A1,GRIN1,YES1,BCAR1,CNTNAP1,SCG2,FGFR2,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,RGMA |
| 2.893e-08 | -17.36 | regulation of cell motility | biological process | GO:2000145 | 666 | 113 | 16441 | 1675 |
NF2,ATP8A1,RET,COL18A1,PKP2,PLXNA1,CD274,CAMK1D,VASH1,HDAC6,PDGFB,EMP2,PDGFA,EPCAM,DAPK2,NOV,SVBP,SP100,KIF14,DAB2IP,TWIST1,TACSTD2,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,CYP1B1,SEMA3B,DOCK4,AKT1,ACVR1C,PTPRU,SYNE2,CCSAP,PTGER4,ARHGDIB,DOCK5,DAG1,ABR,DPYSL3,IRS2,PLCG1,PTPRJ,CORO1C,NKD1,FAM110C,NOD2,NRG1,HSPB1,F2RL1,GAB1,DDX58,SEMA6B,ANXA3,TCAF1,ARAP3,LGALS3,SERPINE2,ADGRG1,SOX9,SDC4,SELL,PKN1,ETS1,FBLN1,SRPX2,LMNA,NRP2,PPP2R3A,HDAC9,CXCL16,ITGA3,ADORA1,IGF1R,CYR61,PTEN,SGK3,SGK1,ADAM15,SORL1,CITED2,EPB41L5,SUN2,RHOA,MPP1,RAPGEF2,PIK3R1,ANO6,FURIN,RGCC,SPATA13,EPHA1,BCAR1,BBS2,GPLD1,ONECUT1,AP1AR,SWAP70,SEMA4D,ACVRL1,PLPP3,PRCP,CSF1,SPINT2,RAP2C,EGFL7,ITGAV,GPER1,PLD1,CFAP20,ARSB,SEMA3A |
| 3.007e-08 | -17.32 | Wilms_tumour | COSMIC cancer mutations | Wilms_tumour | 562 | 97 | 17775 | 1757 |
KIAA1462,PPM1J,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,SS18,WEE1,RPS6KA2,CDH1,PIK3CA,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PTGER4,PRKCQ,ROR1,PKMYT1,IDH1,SLC25A5,MAP3K6,STK17B,ADRBK2,CXXC4,EPHA10,PLCH1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ZNF432,ADRBK1,IGF1R,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,ADCK3,TESK1,AMER1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,MAPKAPK2,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,PER3,JAK3,HIPK3,NRBP1,MELK |
| 3.041e-08 | -17.31 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | 305 | 62 | 17758 | 1761 |
LAMP1,SIGIRR,PACSIN2,PINK1,ZNF395,CDKN1C,LGALS3,TBC1D1,HLA-E,TMX4,HEXB,PDIA5,SELL,ASAH1,IL18,GTF3A,TEX2,ARHGEF40,TSEN34,HDAC9,GNS,APLP2,MDM1,SLC16A6,ZFP36,BHLHE41,MITF,AKR1B1,SORL1,SGK1,RAB20,KLF9,CNPY3,SNX10,ALDH3A2,SLC16A5,FAH,CPD,PPIF,SUN2,TIMP2,MCTP1,CD55,PLSCR1,SNTB1,ZFAND5,SPTLC2,STK17B,RASGRP2,STK17A,MAN2A2,SCARB2,ETS2,ITPR1,CCDC69,NRG1,NR4A2,GLA,PLOD3,LTA4H,F2RL1,IFI6 |
| 3.086e-08 | -17.29 | PEREZ_TP63_TARGETS | MSigDB lists | PEREZ_TP63_TARGETS | 326 | 65 | 17758 | 1761 |
TSC22D3,EPHA4,RET,COL18A1,APC2,FAM46C,SUSD2,SIPA1L2,FRYL,DOK4,REEP1,CNNM4,EPB41L4B,NOTCH3,RASGRP1,LAMP3,MX1,TRIM8,ACVR1C,SLC39A8,SYNE2,RHEB,SOCS3,PGF,HS6ST1,PTPRJ,RAB11FIP1,OVOL1,TLE1,UNC5B,ST3GAL1,HSPB1,PCSK5,COL9A3,TNRC6C,CDKN1C,NUAK1,ZCCHC24,DHRS3,SEPP1,TMEM63A,IL17RB,FRY,IGF1R,VASN,C10orf54,ULBP2,MYLIP,EPB41L5,KCNJ12,LONRF3,TACC1,ZKSCAN2,SPATA13,RUNX3,GRTP1,IFIT3,TP53INP2,GNA11,CRISPLD2,RASGRP2,CACHD1,SEMA4D,ARRB1,SOX8 |
| 3.140e-08 | -17.28 | GSE7852_THYMUS_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_DN | 192 | 45 | 17758 | 1761 |
ILDR1,RUNX2,KIAA1462,CD82,PTTG1,PHLDA1,IL18R1,CARD10,BMP2K,HLA-A,DNAJB9,PLS3,IER3,APOBEC3B,RCN1,BTG3,ITGB8,RPL39,FOSB,RUNDC3B,DAPK1,MDFIC,TAGLN2,TSPAN1,F2R,MBP,PTPN9,PTGER4,LITAF,RUNX3,IGSF8,YES1,STX3,DGKE,FRMD4B,ENPP1,KLF12,NR1D2,LRIG1,NR4A3,NFKBIZ,RELL1,TMEM159,MAFF,XDH |
| 3.140e-08 | -17.28 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | 192 | 45 | 17758 | 1761 |
LAMP1,ARAP3,LGALS3,CD63,CAST,HLA-F,HAL,ASAH1,FAM198B,PRRG4,HLA-A,IER3,ARHGEF10L,GNS,APLP2,FRY,KIF13B,DRAM1,SORL1,CKAP4,CYP1B1,SYPL1,RHOA,MPP1,SAT1,UTRN,CDA,BLVRA,NPC2,LHFPL2,CRISPLD2,FUCA1,HLA-B,MID1IP1,SERPINA1,WIPI1,SIPA1L1,NFKBIA,CLIP4,CLMN,ZDHHC7,CTSA,LTA4H,KLF7,RRAGD |
| 3.140e-08 | -17.28 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | 192 | 45 | 17758 | 1761 |
CDK17,GOLIM4,PARP12,TTC39B,VANGL1,TMX4,ARFGEF1,TDRKH,B4GALT4,LGALS3BP,NEO1,CA2,CDH1,SHC3,IMPAD1,MGAT4A,ZDHHC23,MDFIC,C10orf54,PACSIN1,TIPARP,GCNT1,CPD,SUN2,TIMP2,ELK3,MFI2,IFITM3,COQ10B,RC3H2,LITAF,PRICKLE1,STMN3,CD40,FNDC3A,RAB11FIP2,PHLPP2,ITPR1,LRIG1,PPM1H,SERPINI1,ATP1B3,GLCCI1,AHR,ABCA1 |
| 3.314e-08 | -17.22 | glioma | COSMIC cancer mutations | glioma | 16917 | 1715 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,RNF224,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.336e-08 | -17.22 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 615 | 104 | 17758 | 1761 |
PLA2G4A,LTBP1,TRIM2,KLK10,UGT8,DLGAP5,FOXM1,GALNT12,PTTG1,TAP1,NDC80,RGS20,TP53,NDRG2,IL27RA,MRAS,PHLDA1,CENPN,CYP39A1,APOBEC3B,BTG3,MUC16,CTGF,ARTN,LMO4,ELF5,CDH3,MYBL1,LAMP3,ING1,CENPA,CAPN6,PBK,S100A4,CYB5R2,CDC20,KLK6,NUSAP1,CDK1,FZD7,SOCS3,NFIX,DUOX1,PLCH1,HPSE,GPRC5B,MAP2,PTK7,HOXA9,KLF5,RRAGD,RMND5A,ANXA3,COL9A3,CKAP2,ITGA6,RASA2,CALB2,SOX9,ARL4C,RAB23,CDCA8,C6orf106,GPSM2,S100A2,GSTP1,LBR,ITGB8,SLC27A6,KCNN4,CALD1,NEK2,FXYD5,BUB1,TAGLN2,NCAM1,S100A6,GPR161,CCDC88A,MDFI,CYP26B1,NFE2L3,KLK5,PLSCR1,ASPM,MYBL2,GGH,RUNX3,YES1,SNTB1,NFIB,PLOD2,RND3,SLC2A6,AGBL5,CLIP4,KLK7,HMGA1,CENPE,CCNB2,IFIH1,L1CAM,ARHGEF9,MELK |
| 3.349e-08 | -17.21 | WINZEN_DEGRADED_VIA_KHSRP | MSigDB lists | WINZEN_DEGRADED_VIA_KHSRP | 97 | 29 | 17758 | 1761 |
CYP26B1,AMOTL2,PDGFC,B3GNT2,SERPINE2,CPEB4,PLAUR,ITGA6,SDC4,PTGER4,CCDC68,TFAP2C,GDF15,F11R,PDGFA,CTGF,FRY,SLC4A4,CYR61,ZFP36,TRPC1,NR4A2,NTN4,SERPINI1,NFKBIZ,IFIT1,GEM,SPRY2,PKIA |
| 3.398e-08 | -17.20 | HAMAI_APOPTOSIS_VIA_TRAIL_UP | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_UP | 554 | 96 | 17758 | 1761 |
ARHGAP11A,TRIM2,ARMCX3,CEP70,PAPSS2,DLGAP5,RALBP1,CAST,DNAJC3,CUL4B,NDC80,ARFGEF1,DNAJB11,NUF2,ITPR2,PJA2,DPP8,MNS1,PLS3,ZFYVE16,CDH1,FAM46A,KIF14,MITF,PIK3CA,SNX16,SNX10,METAP2,SULF2,ATL1,SMARCA2,CD55,OSTM1,SH3BGRL,PBK,NUSAP1,RAD17,ATP1B1,ANLN,OPTN,NIN,SOCS3,DNM1L,SLC27A3,ST3GAL1,NRGN,MYL12B,PCSK5,COL9A3,GOLIM4,DEPDC1,ITGA6,ASAH1,KIF23,CTSZ,NUCB2,PPP2R3A,VPS26A,SCML1,KIF5B,B3GALNT1,ADD3,PTEN,CALD1,BHLHE41,MGAT4A,BMP7,FAM13B,KIAA0319,GTF2F2,SORL1,WWP1,ZMYM1,MYO5A,HMMR,PHF20L1,ALDH2,FBLN5,MMD,ASPM,VEZT,GGH,KIF11,PSMA4,NFIB,AP1AR,NMI,ITPR1,MATN2,TCEAL4,CENPE,ETAA1,ITGAV,IFIH1,DOCK9,GOLGB1 |
| 3.412e-08 | -17.19 | regulation of cellular component movement | biological process | GO:0051270 | 737 | 122 | 16441 | 1675 |
LAMP1,NF2,ATP8A1,RET,COL18A1,PKP2,PLXNA1,CD274,CAMK1D,VASH1,HDAC6,PDGFB,EMP2,PDGFA,EPCAM,DAPK2,NOV,SVBP,SP100,KIF14,BCL6,CDKN1B,DAB2IP,TWIST1,TACSTD2,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,CYP1B1,SEMA3B,DOCK4,AKT1,ACVR1C,PTPRU,SYNE2,CCSAP,PTGER4,ARHGDIB,DOCK5,DAG1,ABR,DPYSL3,IRS2,PLCG1,PTPRJ,ATP1A1,CORO1C,NKD1,FAM110C,NOD2,NRG1,HSPB1,F2RL1,GAB1,DDX58,SEMA6B,ANXA3,SCN5A,TCAF1,ARAP3,SERPINE2,LGALS3,ADGRG1,SOX9,SDC4,SELL,TGFBR1,PKN1,ETS1,FBLN1,SRPX2,LMNA,NRP2,PPP2R3A,HDAC9,SNTA1,CXCL16,ITGA3,ADORA1,IGF1R,CYR61,PTEN,MEGF8,SGK3,SGK1,ADAM15,SORL1,CITED2,WNT3A,EPB41L5,SUN2,RHOA,MPP1,RAPGEF2,PIK3R1,ANO6,FURIN,RGCC,SPATA13,EPHA1,BCAR1,BBS2,GPLD1,ONECUT1,AP1AR,SWAP70,SEMA4D,ACVRL1,PLPP3,PRCP,CSF1,SPINT2,RAP2C,EGFL7,ITGAV,GPER1,PLD1,CFAP20,ARSB,SEMA3A |
| 3.470e-08 | -17.18 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 481 | 89 | 11866 | 1235 |
CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,CAMK1D,GRK6,DDR1,PRKACA,DAPK2,WEE1,RPS6KA2,PASK,PLK4,EPHB4,SCYL3,MAP3K3,PLK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,CDK1,EPHA10,JAK1,STK26,CDK19,PLK2,PTK7,STK38,LIMK1,AXL,MLKL,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,TGFBR1,TEC,TRIB2,PKN1,MERTK,BMP2K,ADRBK1,IGF1R,CDK16,SGK3,NEK2,MAP3K9,PRKG1,DAPK1,SGK1,MAPK11,BUB1,ERBB3,PIM1,MAST4,SYK,TESK1,STRADB,EIF2AK1,YES1,EPHA1,PDIK1L,STK17A,MAPKAPK2,FGFR2,ACVRL1,CSNK1G1,RYK,AURKA,STK39,CDK18,LRRK1,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 3.476e-08 | -17.17 | HALLMARK_MITOTIC_SPINDLE | MSigDB lists | HALLMARK_MITOTIC_SPINDLE | 199 | 46 | 17758 | 1761 |
BIN1,ARHGEF3,ARAP3,DLGAP5,ARHGEF11,RALBP1,RASA2,NDC80,ARFGEF1,KIF23,HDAC6,SAC3D1,KIF5B,TOP2A,CNTRL,TBCD,DLG1,NEK2,BUB1,CTTN,CLIP2,TIAM1,CCDC88A,PLK1,DOCK4,SUN2,PCGF5,EZR,NUSAP1,PIF1,ANLN,BCAR1,KIF11,CDK1,RANBP9,RASA1,ABR,NIN,MID1IP1,FGD6,AURKA,CENPE,ARF6,CCNB2,SHROOM2,ESPL1 |
| 3.884e-08 | -17.06 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 259 | 55 | 17758 | 1761 |
FBLIM1,KLK10,CPEB4,CAST,RUSC2,DAP,UBASH3B,GALNT12,ITGA6,EPS8,SNN,CRABP2,HDAC6,DPP8,PHLDA1,LGALS3BP,DAPK2,KIF5B,APLP2,CPNE2,UBE2Q2,KCNN4,FLRT3,KLF3,ALDH1A3,DLG1,TINAGL1,TIPARP,GM2A,CCDC88A,ABCC1,MYO5B,HMMR,ARAP2,FMN1,UTRN,FOS,RANBP9,BCAR3,IRS2,SHROOM3,SEMA4D,PLK2,RAB11FIP1,CLIP4,YOD1,NRG1,SERPINB6,PLD1,RAP1GAP,HOOK1,HIPK3,CMTM4,ABCG1,XDH |
| 3.938e-08 | -17.05 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | 187 | 44 | 17758 | 1761 |
BIN1,SIGIRR,SLC35D2,HECA,CCDC109B,TSC22D3,EPHA4,TMX4,ARL4C,HERC5,NDRG2,NUCB2,FAM46C,TOP2A,MARCH8,ADD3,LYPD3,MGAT4A,KLF3,PIK3CA,SORL1,CRY2,PDE4D,PIKFYVE,CITED2,MYBL1,TRIM62,SUN2,S100A4,SH3BGRL,PIK3R1,PRKCQ,ARHGDIB,FOS,MYL12A,RASGRP2,IRS2,PLCG1,RAB11FIP2,NR4A2,FHL1,MAP3K5,NR3C2,TOB1 |
| 4.087e-08 | -17.01 | membrane | cellular component | GO:0016020 | 8775 | 984 | 17570 | 1756 |
HECA,ACACB,ADD1,IL15RA,MRPS15,SLC25A13,DNAJC3,HEXB,RET,CACNA2D2,FBXO2,NRG2,TGOLN2,LYNX1,MORF4L2,SYTL4,CMTM6,GRM5,SMIM13,CALM2,PSMD1,PQLC2,AP1M2,MUC4,CABP1,CYP2S1,PAQR5,FUT1,CLDN4,PIK3CD,TMEM37,RNF26,TIAM1,MGAT5,ERAP2,TMEM151A,PRKAR2B,LOXL2,F12,ICMT,PPP1R14C,RNF19B,CYP4F3,ARF4,ABR,PGF,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,NOD2,AGFG2,MRPS28,RELL1,ARF6,HSPB1,SCN5A,FAM169A,GGA1,ITGA6,RAB23,SLC36A4,COX6C,FAM21C,MERTK,TTYH3,LMNA,MARCH8,FAM189A1,ATP5H,MEGF8,FLRT3,PCYOX1,CADPS2,PANX2,NCAM1,ULBP2,MYLIP,DGKG,NDUFA12,NUP85,PPP6R1,PAQR7,SLC37A1,PQLC3,ERO1A,SPTLC2,GNA11,SFXN5,CYB5A,PTPRF,CACHD1,SCARB2,SLC4A4,ETS2,TIMM8A,SEMA4D,ITPR1,RAET1L,CLMN,STK39,MAL2,DRP2,NDE1,ARPC2,TMEM159,SERPINB1,NUP58,TMEM173,RUSC1,DOCK9,MTM1,CCDC109B,GRHL2,GALNT12,INPP5D,CD82,RGS20,PKP2,NUF2,IL13RA1,GRK6,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,APPBP2,CDS1,CCND1,MUC16,SCNN1A,CDH1,XYLT2,ENPP5,RTKN2,ACSL4,LRP11,ARL4D,DLG3,RAB27B,SNX10,TMEM9,SCN3A,MX1,TMEM200B,ENPP4,SEC61B,COL6A2,FZD4,PLEKHO1,SYNE2,CYS1,HTATIP2,DNAJB14,RAB38,XRCC6BP1,SNX12,COX20,GABARAPL1,IRS2,ALDH3B1,SHROOM3,WFS1,CORO1C,SLC9A6,AXL,SIPA1L1,PNPLA6,TRABD2A,PRIMA1,RGS14,SLC25A30,TTC8,TCAF1,SDC4,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,NUCB2,SLC25A43,SRPX2,SGPL1,NEO1,DIRAS3,CXCL16,ADD3,FUT2,ITGB8,IGSF9,SLC27A6,CTSC,ANKS1B,CALD1,ALG13,MGAT4A,FAM20B,CST3,BAX,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,IGFBP2,NPTXR,SGCB,TPCN1,S100A6,PARP9,ACBD5,AMOTL2,PVRL4,PLSCR1,FMN1,RAPGEF2,MFSD2B,PIK3R1,EIF5A2,ELOVL3,MRS2,GRIN1,SNTB1,CNTNAP1,GALNT3,RPL12,PLOD2,RAB11FIP2,ACVRL1,SYT7,ITGAV,CENPE,FHL1,WDR45B,DCBLD1,CYBRD1,TMEM131,SIGIRR,ILDR1,BCAM,EPHA4,ARFGEF1,NDC80,DNAJB11,F11R,TEX2,NENF,ITPR2,TP53I11,MGAT5B,HDAC6,PDGFB,SDC1,SPTB,FANCI,SUSD2,CPNE2,RPS6KA2,NPNT,SHC3,CNTRL,IL6ST,SLC44A1,TMEM143,ABCA2,NTN4,TLN2,ANO4,SCARA3,TRAM1,SMAGP,CD55,KCNIP3,MCTP1,CELSR2,STAU2,NFE2L1,CR2,EZR,KLK6,ARFRP1,PRKRA,LHFPL2,CDK1,RHEB,OPTN,TMEM164,PLCH1,HS6ST1,MFAP3L,KCNMB4,AGPAT2,WIPI1,DOLPP1,RAB11FIP1,PRKCDBP,ARRDC1,PIK3C2B,PIEZO1,EPB41L4A,RRAGD,PRSS8,LMTK3,BMF,LGALS3,FXYD3,RASA2,HLA-F,SLC22A31,ADCK5,RAB6A,NCKAP1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,ANO1,B4GALNT1,IGF1R,FRAS1,TBCD,EXOC8,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,ALDH3A2,CKAP4,ABCC1,CYP26B1,CHSY3,MRPS33,PCDH1,BTNL9,RGMB,MGAT4B,SPATA13,EMC2,SCRIB,PRX,CDK5R1,RASGRP2,EPN3,COQ10A,COL13A1,PVRL2,PHLPP2,ITGA7,MFSD2A,CSF1,SLC2A6,ZDHHC7,PLD1,ATP1B3,TMEM120A,CCNB2,SMCO4,IFI6,NIPA1,NF2,XYLT1,TMX4,ERBB2,FAM198B,SLC7A2,LPIN3,EMP2,BCAP31,CYP26A1,SYTL2,IER3,PDGFA,ATP6V0B,WDR44,EFR3A,PLCG2,N4BP3,SRR,ZDHHC23,CDH3,VAT1,NOTCH3,OAS3,TMEM64,SCN2A,LMAN1,GM2A,DVL2,SULF2,CPD,PPIF,SIRT1,TMTC1,CLCN3,MBP,EVA1A,AKT1,COQ10B,PTGER4,DAG1,ATP13A2,DUOX1,TAPBP,DNAJC10,PTPRJ,ATP1A1,PRRT4,IDE,ABHD12,MMP17,PTK7,EFNA5,IRF7,SYT13,C1orf43,AIFM3,ST3GAL1,TMEM263,NDST3,CMTM4,ARFGEF3,MAN2B2,BIN1,CMAS,PINK1,MFSD14B,TM2D2,PACSIN2,GOLIM4,TOR4A,CDH22,CD63,ADGRG1,BLVRB,GABRG2,SELL,DSE,LBR,AIP,PARM1,VPS26A,DNAJB9,FZD6,SLC9A2,SIRPA,NRP2,M6PR,ZDHHC21,CD109,CDK16,ALPP,UBE2J1,SGK1,BUB1,TSPAN13,ABCD1,KLF9,SYK,ATP2B1,GCNT1,IGDCC4,HMMR,DLGAP1,RHOA,MOSPD2,IFITM3,GUSB,CRB3,AMFR,PLAUR,LITAF,PRICKLE1,COL7A1,FNDC3A,BCAR1,RNPEP,BBS2,TXNDC11,MAPK8IP1,DGKE,CD83,SERPINA1,FAT4,TMC5,NETO2,PGRMC1,SPCS3,ICOSLG,FER1L4,NDFIP1,TBC1D4,PTGES,ZBTB33,ARHGEF4,DIS3L,GOLGB1,SUN1,LAMP1,SLC35D2,GAA,SSH1,LGR4,HSPG2,VANGL1,TMEM41B,ATP8A1,TAP1,PLXNA1,CCNB1,PJA2,SLC20A1,NCS1,SLC9A7,CYP1A1,CTGF,STIM1,ELMO2,OSBPL3,RGS3,IL31RA,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,ATRNL1,TACSTD2,HYLS1,MARCH2,ARMCX6,PACSIN1,METAP2,XKR8,LAMP2,ORAI2,SGCE,TMEM68,SPATA18,ACVR1C,SNTB2,SLC35C1,AGO4,KIF13A,GALNT7,MCFD2,SLC25A5,POR,SPNS3,PRIM1,SLC25A4,GDE1,GNPTAB,NKD1,LRIG1,SARAF,UNC5B,F2RL1,TRAF5,LZTS1,DDX58,SEMA6B,MRPL44,MRC2,SCOC,TMEM55B,HLA-E,DGKQ,SLC25A27,NDUFA4,SLC1A3,TNFRSF19,TSPAN7,KIAA1161,PRRG4,MESDC2,C9orf69,DOPEY2,ITGA3,RALGPS2,SNX18,LYPD3,ZNRF2,PIK3AP1,VASN,SLC16A6,BDH1,DAPK1,TPST1,ADCK2,TMEM51,PRKG1,OPN3,SORL1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,SYTL3,GPR161,RIMS2,IGSF3,TRAK2,FAM69A,EPB41L5,FADS2,PMPCB,PRODH,B3GNT7,KCNJ12,MMD,MFI2,ADCK3,MICB,LPGAT1,CALM1,AMER1,ANO6,PIP4K2C,VEZT,EPHA1,ATP8B3,ANTXR1,GLT8D2,RASA1,STX3,FAS,DGKH,MMP15,SLCO4A1,GABRD,PLEKHH2,TJP3,TMEM54,FAAH,SLC4A3,PCDH19,PLIN3,MAP3K5,HOOK1,NRBP1,EHD1,PLA2G4A,MFSD3,SPRED1,SLC2A4,CEP70,ARMCX3,TCTN2,NLRX1,ST14,TRIP10,IQGAP1,CAST,RALBP1,BROX,ATP2C2,RNF182,KCTD12,TMEM170B,CD274,BCL2L1,SNN,AIFM2,DDR1,CYP39A1,TMPRSS4,ZFYVE9,EPS8L2,APLP2,ACAP2,BRI3,CNNM4,DAB2IP,PDE4D,EPHB4,PHKA2,TSPAN1,GPX4,MYO5B,DOCK4,SEC23A,COG2,CYB5R2,PANK1,UTRN,TMEM144,PRKCQ,SLC11A2,ATP1B1,PKMYT1,ITPR3,ALCAM,TRIQK,ATP10D,FZD7,CMTM7,EPHA10,JAK1,DDOST,PPP2R5A,POPDC3,STK26,TSPAN18,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,SLC27A3,NR3C2,COBL,DENND5B,ATP9A,EPS8,ARL4C,EFHD2,CYB561,EFNB1,LGALS3BP,ADGRB2,HLA-A,WWP2,TMCC3,SLC25A36,SNTA1,AKIRIN1,TMEM87B,GNB5,RNF128,PTEN,FUT8,DRAM1,CD9,ATP8B1,SLC44A2,ERBB3,SLC16A5,SPRY2,FARP2,PDGFC,RASGRF1,ARHGEF28,B3GNT2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,YES1,AIF1L,FOS,KIF11,CPTP,GPLD1,NUCB1,MAMDC4,FGFR2,ABCB1,RYK,ERAP1,GRIN2D,GPER1,FZD5,NCAPG2,SLC25A38,DEF6,OCLN,MELK,ESYT2,RGMA,CASP3,UGT8,CPT2,MPP5,CACNB4,DNER,SLC8B1,ERP29,KREMEN1,TMC1,PTCHD4,SH3KBP1,HTR1D,ABCD4,CHPF,ZFYVE16,EPCAM,NKAIN3,RAB15,METTL7A,TSPAN6,IMPAD1,DPYSL2,DLG1,TRPC1,SUN3,RAB20,RP2,MYH14,CTTN,SLC39A10,TECR,PTPRE,MYRIP,RASGRP1,LAMP3,CYP1B1,ATL1,ITCH,ARHGDIB,ROR1,PTGFRN,MRPS36,TYSND1,STK17B,EDNRA,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ADIPOR1,LEMD1,NRGN,RAP1GAP,CAPN1,CPPED1,PCSK5,STARD3NL,CD99,ARAP3,SERPINE2,PEX6,BVES,ABCG2,CALM3,TEC,PHLPP1,B3GALNT1,CA2,KCNN4,COL6A1,SUCO,FXYD5,C10orf54,HLA-C,NCEH1,SLC12A2,GAD1,CCDC88A,SNX7,KDELR1,PODXL2,GYLTL1B,BTN3A2,NUBP1,C3orf58,MFSD7,STEAP1,GLCE,GNAS,FECH,XKRX,SLC6A6,UAP1,PLPP3,TMEM30A,NFKBIA,CDCA5,SH3BP4,RHOBTB2,CTSA,SHROOM2,TMEM14A,JAK3,APOL2,RARG,SNX30,PROM2,DYNLRB1,SLC25A24,SORBS1,IL15,PSME2,HDAC11,PDIA5,IL27RA,MRAS,PHLDA1,LRRC45,SLC25A48,CYP4F11,ZDHHC12,KIF14,REEP1,RPN2,ECE1,EPB41L4B,F2R,PDIA6,FRS3,SEPHS1,CHP1,SUSD3,GCA,PTPRU,SLC39A8,OSTM1,C3orf52,IGSF8,ERBB2IP,CD40,CASP4,JADE1,BFSP1,SECTM1,PEX2,VSIG10,SPTBN5,CYP2U1,REEP4,ABCA1,LIFR,ANXA3,SORT1,ENO2,TSPAN15,ARHGEF11,CIT,FRMD6,LRP4,FAM134A,TGFBR1,SBF1,POMGNT1,TMEM63A,KIF5B,IL17RB,ADORA1,ADRBK1,LLGL2,A4GALT,RRBP1,KIAA0319,ARVCF,IQGAP3,MYO5A,B3GALT6,SUN2,SYPL1,RAB3B,NR4A1,TMEM245,RC3H2,SYBU,LRRC66,LEPR,ENDOD1,HLA-B,SWAP70,RND3,TRIM69,PRCP,HNRNPH2,CTSV,SPINT2,RAP2C,ARRB1,GRAMD1C,MCUR1,GEM,PLOD3,CEP41,L1CAM,CD33,ABCG1,SNPH |
| 4.126e-08 | -17.00 | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 213 | 48 | 17758 | 1761 |
GRN,LTBP1,CCDC109B,MRC2,RUNX2,IL15RA,IGFBP6,LGALS3,S100A11,ST14,IQGAP1,CAST,BLVRB,HEXB,TGOLN2,CTSZ,MGST2,DSE,SRPX2,PLS3,TYMP,SP100,CTSC,AIM1,DRAM1,FXYD5,S100A13,GCNT1,SYPL1,S100A4,PLAUR,SAT1,FURIN,PTGER4,NPC2,LHFPL2,CASP4,ALDH3B1,SWAP70,RBM47,SERPINA1,UAP1,P4HA2,RAB11FIP1,NR4A3,NOD2,LTBP2,CYBRD1 |
| 4.372e-08 | -16.95 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 45 | 17758 | 1761 |
CASP3,SPC25,ARMCX3,ENO2,DEPDC1,DLGAP5,FOXM1,RASA2,PTTG1,KIF23,MORF4L2,NANS,CCNB1,FANCI,SAC3D1,TNS3,ADCK2,TUBG1,MANF,LGMN,SEPHS1,METAP2,PPIF,KIF20A,ASPM,PBK,SNTB2,CDC20,ITPR3,KIF11,DCP2,BCAR3,FUCA1,RAB11FIP1,LRRK1,CENPE,HMGA1,PLIN3,ARPC2,NCAPG2,TBC1D4,CCNB2,UBE2C,ESPL1,MELK |
| 4.477e-08 | -16.92 | PILON_KLF1_TARGETS_DN | MSigDB lists | PILON_KLF1_TARGETS_DN | 1896 | 257 | 17758 | 1761 |
HECA,MRPS15,DNAJC3,FAM102B,MORF4L2,FAM101B,CARD10,CMTM6,WEE1,KLF3,ATRNL1,PIK3CD,TIAM1,LAMP2,TMEM68,PBK,PIF1,GALNT7,SLC25A5,SPNS3,PRIM1,ANKRD10,PIAS3,GNPTAB,HDAC1,RELL1,ARF6,MRPL44,CDK17,FRMD4A,ALDH6A1,ITGA6,COX6C,TFAP4,FRY,ZNRF2,PAIP2B,SNX18,PPP4R1,PCYOX1,SORL1,ZMYM1,MYLIP,FAM69A,KIF20A,LPGAT1,FAM133B,NPC2,STX3,SCARB2,TIMM8A,DCK,ITPR1,MDH1,MAP3K5,NDE1,SERPINB1,TMEM173,ARHGAP11A,PLA2G4A,PAPSS2,S100A11,RPS6KA1,CAST,IQGAP1,C5orf30,KCTD12,NUF2,TMEM170B,GRK6,REPS1,APPBP2,APOBEC3B,ACAP2,PHKA2,PTPN9,PANK1,NUSAP1,PKMYT1,ATP1B1,RAB38,CMTM7,NIN,ALDH3B1,PPP2R5A,CDK19,SLC9A6,SIPA1L1,SLC25A30,ISOC1,TNRC6C,EFHD2,CTSZ,ETS1,TIPRL,DTX3L,AKIRIN1,FAM111A,E2F7,ADD3,PTEN,CTSC,FUT8,CST3,FAM20B,SGK3,SLC44A2,TMBIM6,TAGLN2,CNOT6L,TPCN1,NCOA2,PARP9,ALDH2,PLSCR1,TACC1,BCL9,PIK3R1,UBE2A,C1GALT1C1,DCTN6,DBI,ERAP1,CSTF2,ITGAV,ARSB,MELK,DEF6,ACOT7,ESYT2,JARID2,CASP3,ARFGEF1,TEX2,SH3KBP1,RPS6KA2,IMPAD1,DPYSL2,AKR1B1,RP2,TRAM1,PTPRE,PCGF5,ING1,ITCH,ARFRP1,ARHGDIB,ANLN,LHFPL2,SESN1,ZBTB7B,IDH1,ADRBK2,STK17B,RHEB,MAN2A2,TMEM164,MSL1,AGPAT2,CAB39,MYL12B,NR2C2,LASP1,ARAP3,PPP1R2,LGALS3,RASA2,PDCL,ASAH1,B4GALNT1,TNS3,IGF1R,RINL,GATA2,KCNN4,TBCD,EXOC8,C10orf54,RFX5,ALDH3A2,MPHOSPH9,CKAP4,ABCC1,ELK3,CORO2A,OXR1,HEATR5A,RANBP9,SLC6A6,KBTBD2,PRPS2,PITPNA,ATP1B3,SNX30,RNF146,SLC25A24,UGP2,TMX4,TTC21B,SS18,SETDB2,EFR3A,PLCG2,PLK4,TMEM64,LMAN1,PDIA6,SCYL3,GM2A,SULF2,MAP3K3,SIRT1,MBP,AKT1,FIGNL1,OSTM1,KCTD2,DOCK5,ATP13A2,DNAJC10,IDE,RBL1,STK38,BHLHB9,ANXA3,TM2D2,CIT,ERI2,SELL,TGFBR1,TRIB2,LBR,VPS26A,HMGXB4,TMEM63A,GTF2F2,TRIM21,TSPAN13,ABCD1,IQGAP3,SYK,SYPL1,NR3C1,GUSB,RC3H2,MBNL3,GGH,SWAP70,RAP2C,NMI,DTX4,PPP2R3C,SPCS3,ZMIZ1,HIPK3,ZBTB33,CD33 |
| 4.520e-08 | -16.91 | epidermal growth factor receptor signaling pathway | biological process | GO:0007173 | 321 | 65 | 16441 | 1675 |
SPRED1,REPS2,PSME2,IQGAP1,NRG2,ERBB2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,SH3KBP1,PDGFA,CALM2,PSMD1,SHC3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKAR2B,AGO4,ERBB2IP,ITPR3,ARF4,IRS2,PLCG1,JAK1,NRG1,SPTBN5,GAB1,TNRC6C,RASA2,EPS8,SOX9,PSMD10,CALM3,PHLPP1,FGF19,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,SOCS5,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,PSMA4,RASA1,FGFR2,PHLPP2,ITPR1,GRIN2D,JAK3 |
| 4.522e-08 | -16.91 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 379 | 72 | 17758 | 1761 |
GAA,LZTFL1,ATP8A1,FBXO2,LMCD1,ERBB2,F11R,FANCI,CDS1,FAM46A,CTGF,METTL7A,KLF3,CLDN4,LGMN,CYP1B1,COL6A2,CAPN6,S100A4,SAT1,TNS1,LDB2,ENPP1,ANKRD6,PTK7,SECTM1,NRG1,NR3C2,RRAGD,RUNX2,ZNF395,ALDH6A1,ITGA6,SOX9,CALB2,CRABP2,SEPP1,S100A2,H1FX,LMNA,MECOM,ITGA3,KCNN4,FUT8,TOX2,ADAM15,TSPAN13,LIMCH1,ABCD1,ERBB3,MAST4,GAD1,SLC16A5,ALDH3A2,MPP1,AMFR,CXorf57,AK4,IFIT3,FUCA1,PELI2,MATN2,SPINT2,CCDC69,ARRB1,FHL1,HMGA1,SHROOM2,RARG,PKIA,ZBTB33,KLF7 |
| 4.589e-08 | -16.90 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 430 | 82 | 8202 | 867 |
CASP3,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,NRG2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,CALM2,PDGFA,PSMD1,RPS6KA2,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,ABR,IRS2,PLCG1,PPP2R5A,JAK1,NGFRAP1,HDAC1,NRG1,SPTBN5,GAB1,MAPK12,PCSK5,FGD1,TNRC6C,ARHGEF3,ARHGEF11,RASA2,CALM3,PSMD10,PHLPP1,FGF19,ADRBK1,PTEN,MAPK11,ERBB3,NCAM1,RASGRF1,RHOA,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,FURIN,ELK1,PSMA4,RASA1,MAPKAPK2,FGFR2,PHLPP2,ITPR1,NFKBIA,ARRB1,GRIN2D,JAK3,ARHGEF9,ARHGEF4 |
| 4.655e-08 | -16.88 | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | 188 | 44 | 17758 | 1761 |
PLA2G4A,ARMCX3,FRMD4A,REPS2,GNPDA1,HEBP1,SLC25A13,RAB23,PBX3,IL13RA1,TEX2,BCL2L1,MGST2,NTAN1,PPP2R3A,DPYSL2,PAQR5,GALNS,ADAM15,TECR,CLIP2,CKS2,SOCS5,PPIF,AMOTL2,MRPS33,SAT1,ACO1,PCTP,RNPEP,ALCAM,KIF11,CD83,FUCA1,SLC6A6,H1F0,CSF1,DBI,CLIP4,CLMN,ADIPOR1,FZD5,HSPB1,NRGN |
| 4.655e-08 | -16.88 | GSE7852_LN_VS_THYMUS_TCONV_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_DN | 188 | 44 | 17758 | 1761 |
EXPH5,LZTFL1,TXN,ENO2,DEPDC1,FRMD6,IQGAP1,HAL,FAM102B,ITPR2,ZDHHC21,IL17RB,TOP2A,CTSC,FUT8,ALDH7A1,NTN4,PLK1,CENPA,FIGNL1,PBK,CDC20,CCDC34,PRICKLE1,PDE5A,PRKAR2B,NUSAP1,CCNF,PRKRA,PTGFRN,CDK1,STX3,PRIM1,PTPRF,ALDH5A1,NGFRAP1,ABHD12,CDCA5,CENPE,NCAPG2,UBE2C,ESPL1,E2F8,MELK |
| 4.655e-08 | -16.88 | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | 188 | 44 | 17758 | 1761 |
DDX58,PARP12,PSME2,TAP1,KIF23,HERC5,SAMD9,FBXO6,HERC6,LGALS3BP,BMP2K,DTX3L,SP100,PIK3AP1,EFR3A,ZNRF2,IFIT1,OAS3,PARP9,LAMP3,MX1,ZWINT,PLSCR1,IFITM3,OSTM1,PBK,USP18,C1GALT1C1,BLVRA,IFIT3,PSMA4,SCARB2,TRIM69,C19orf66,NAT1,SECTM1,NMI,AURKA,IRF7,MRPS28,PPP2R3C,CMPK2,IFIH1,IFI6 |
| 4.691e-08 | -16.88 | positive regulation of protein kinase activity | biological process | GO:0045860 | 596 | 103 | 16441 | 1675 |
SPRED1,TXN,AVPI1,PSME2,CAMKK1,IQGAP1,EPHA4,NRG2,ERBB2,PSME1,PRKACA,PDGFB,STIL,ERP29,EMP2,CARD10,SPTB,GRM5,CALM2,CCND1,PDGFA,PSMD1,SHC3,KIF14,PIK3CA,DLG1,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,MAP3K3,SIRT1,RIPK2,AKT1,FZD4,PRKAR2B,CD40,CDK1,MAP3K6,IRS2,PLCG1,GPRC5B,JAK1,STK26,MADD,NOD2,CAB39,SLC27A1,EFNA5,SPTBN5,NRG1,GAB1,PINK1,NKX3-1,RASA2,SDC4,CALM3,PSMD10,TGFBR1,PKN1,FGF19,ADORA1,CYR61,BAX,MAP3K9,MAPK11,MDFIC,PIM1,ERBB3,NCAM1,WNT3A,IQGAP3,SYK,SPRY2,CCDC88A,MDFI,PDGFC,RASGRF1,MMD,PSMB4,RAPGEF2,CALM1,GRIN1,RGCC,STRADB,PDE5A,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,FGFR2,CSF1,ARRB1,PPP2R3C,GRIN2D,STK39,CENPE,FZD5,MAP3K5,JAK3 |
| 4.776e-08 | -16.86 | regulation of Rho protein signal transduction | biological process | GO:0035023 | 107 | 31 | 16441 | 1675 |
RASGRF1,ARHGEF3,ARAP3,ARHGEF28,ADGRG1,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,EPS8L2,ABR,ARHGEF26,ARHGAP35,ARHGEF10L,PLEKHG6,ARHGEF19,ITGA3,ARHGEF37,PLEKHG1,BCL6,FGD6,ARRB1,TIAM1,F2R,F2RL1,ALS2CL,ABCA1,ARHGEF9,ARHGEF4,FARP2,FGD1 |
| 4.861e-08 | -16.84 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | 93 | 28 | 17758 | 1761 |
GAS2L1,AMOTL2,INPP5D,NFE2L1,GTF3A,LOXL2,ASB13,NFIB,DAG1,GNA11,GABARAPL1,BCAR3,CCND1,SWAP70,ADRBK1,PLK2,IL6ST,FAM114A1,DRAM1,TFAP2A,BMP1,SGK1,TNFRSF12A,ITGAV,PPP6R1,DEF6,CKAP4,IGSF3 |
| 4.985e-08 | -16.81 | ruffle | cellular component | GO:0001726 | 156 | 39 | 17570 | 1756 |
DDX58,MTM1,PACSIN2,ARAP3,NF2,S100A11,CIT,IQGAP1,EPS8,EPS8L2,RINL,TNFRSF12A,CTTN,TLN2,PACSIN1,SPRY2,S100A6,MYO5A,EPB41L5,RHOA,SPATA13,EZR,AIF1L,BCAR1,ARF4,ARHGEF26,RASA1,FRMD4B,RASGRP2,KLHL2,GNAS,PLCG1,PTPRJ,FGD6,ITGAV,ARF6,COBL,ARHGEF4,FGD1 |
| 4.997e-08 | -16.81 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 234 | 51 | 17758 | 1761 |
GRN,ANXA3,SIGIRR,IL15RA,SERPINE2,EPAS1,HEXB,TAP1,HERC5,BCL2L1,PHLDA1,RABGGTA,FUT8,IRF2,MTMR11,PIKFYVE,ZMYM1,LAMP3,DOCK4,TGIF1,CD55,RIPK2,PLSCR1,MOSPD2,SLC39A8,PLAUR,CYB5R2,OXR1,LYRM1,SAT1,LHFPL2,RNF19B,CASP4,SOCS3,DCTN6,CARHSP1,SLCO4A1,MID1IP1,SERPINA1,ETS2,UAP1,WIPI1,RND3,NMI,FGD6,IRF7,MAP3K5,ITPKA,SERPINB1,ABCA1,EGLN1 |
| 5.021e-08 | -16.81 | positive regulation of transferase activity | biological process | GO:0051347 | 688 | 115 | 16441 | 1675 |
SPRED1,TXN,AVPI1,GRHL2,PSME2,CAMKK1,IQGAP1,EPHA4,NRG2,ERBB2,PSME1,CCNB1,PRKACA,PDGFB,STIL,ERP29,EMP2,CARD10,SPTB,GRM5,CALM2,CCND1,PDGFA,PSMD1,SHC3,KIF14,SERINC2,PIK3CA,DLG1,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,PLK1,MAP3K3,SIRT1,RIPK2,AKT1,FZD4,CDC20,PRKAR2B,PRKCQ,CD40,CDK1,MAP3K6,IRS2,PLCG1,GPRC5B,JAK1,STK26,MADD,NOD2,CAB39,SLC27A1,EFNA5,SPTBN5,NRG1,GAB1,PIFO,PINK1,NKX3-1,RASA2,SDC4,CALM3,PSMD10,TGFBR1,PKN1,FGF19,PARM1,ADORA1,CYR61,PTEN,NEK2,BAX,MAP3K9,SORL1,MAPK11,MDFIC,PIM1,ERBB3,NCAM1,WNT3A,IQGAP3,SYK,SPRY2,CCDC88A,MDFI,PDGFC,RASGRF1,MMD,PSMB4,RAPGEF2,CALM1,GRIN1,RGCC,STRADB,PDE5A,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,FGFR2,CSF1,ARRB1,PPP2R3C,GRIN2D,STK39,CENPE,FZD5,MAP3K5,JAK3,UBE2C |
| 5.146e-08 | -16.78 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | 195 | 45 | 17758 | 1761 |
ARHGAP11A,SPC25,DLGAP5,HJURP,CIT,NDC80,KIF23,NDUFA4,NUF2,MGST2,STIL,MNS1,CENPN,NRP2,TOP2A,SIVA1,GALNS,BDH1,ELF5,NEK2,PLK4,BUB1,SCN2A,C12orf75,CKS2,CENPA,KIF20A,FIGNL1,ASPM,VWA1,NUSAP1,TCF7,PIF1,PKMYT1,CCNF,ETS2,CDCA5,DBI,FAM110C,CENPE,NCAPG2,CCNB2,ESPL1,E2F8,MELK |
| 5.186e-08 | -16.77 | regulation of cell differentiation | biological process | GO:0045595 | 1454 | 210 | 16441 | 1675 |
EMX1,SSH1,EPHA4,RET,IL18,MORF4L2,PLXNA1,CAMK1D,HDAC6,FAM101B,LTBP3,GRM5,NCS1,CTGF,NPNT,IL6ST,DPYSL2,MITF,ELF5,DUSP10,TACSTD2,SEMA3G,CTTN,PACSIN1,TIAM1,RASGRP1,KLK6,LOXL2,SAV1,CDK1,POR,RHEB,DPYSL3,ENPP1,GPRC5B,PLK2,LIMK1,HOXA9,HDAC1,ITPKA,ARF6,MAFF,LZTS1,GRN,SEMA6B,RUNX2,SERPINE2,LGALS3,UBASH3B,SOX9,ETV5,FBLN1,FAM21C,MECOM,ITGA3,CA2,CYR61,GATA2,MEGF8,BHLHE41,VASN,KIF13B,SUCO,SORL1,TNFRSF12A,C10orf54,WNT3A,CCDC88A,RIMS2,SOCS5,EPB41L5,MMD,MFI2,HMG20B,PDE5A,NPHP3,GNA11,CDK5R1,FAS,SOX13,GNAS,PTPRF,AP1AR,NCOA3,SEMA4D,SETD3,CSF1,TMEM30A,NFKBIA,AURKA,FAM213A,GDF11,ARPC2,MAP3K5,JAK3,SEMA3A,TOB1,RARG,XDH,EHD1,GAS2L1,FOXO6,NF2,GRHL2,IL15,THRA,INPP5D,RPS6KA1,TP53,ERBB2,PKP2,PRKACA,EMP2,APC2,TNFSF9,CCND1,NOV,DACT1,LMO4,KIF14,BCL6,DAB2IP,DIXDC1,TWIST1,TMEM64,NOTCH3,SEMA3B,SIRT1,SSH3,TIMP2,RIPK2,AKT1,CDC20,DAG1,FZD7,ARHGAP35,SOCS3,BHLHB9,AXL,PTK7,CORO1C,SIPA1L1,INPP4B,TRIOBP,KLF5,NRG1,IRF7,EFNA5,RGS14,COBL,ABCA1,MAPK12,BIN1,CTHRC1,SORT1,ADGRG1,CIT,LRP4,TGFBR1,GDF15,CRABP2,TRIB2,ETS1,TEAD3,SIX4,HDAC9,NEO1,CD109,CTNNBIP1,PTEN,BMP7,MYCL,KIAA0319,TFAP2A,BAX,MAPK11,SYK,TRIM62,SPRY2,TLE6,TGIF1,HES1,RHOA,ASPM,RAPGEF2,PIK3R1,GRIN1,PPARA,RGCC,MBNL3,PRICKLE1,RUNX3,FOS,CD83,CDK5RAP1,HLA-B,FAT4,FGFR2,NR1D2,ACVRL1,TWSG1,PPP2R3C,ITGAV,GPER1,OSR1,SOX8,ARSB,NDFIP1,L1CAM,ABCG1 |
| 5.198e-08 | -16.77 | regulation of apoptotic process | biological process | GO:0042981 | 1404 | 204 | 16441 | 1675 |
CASP3,TRIM2,TSC22D3,DNAJC3,RET,PSME1,CAMK1D,BARD1,ERP29,CARD10,EPCAM,DAPK2,PSMD1,RPS6KA2,CTGF,IL6ST,SIVA1,ALDH1A3,IL31RA,MITF,PIK3CA,CTTN,SLC39A10,TIAM1,CYP1B1,PLK1,KCNIP3,ACVR1C,ITCH,CASP9,SAV1,PRKRA,SLC25A5,CDK1,POR,STK17B,ARF4,ABR,OPTN,MDK,DNM1L,PLK2,MADD,NOD2,HDAC1,KLF11,UNC5B,HSPB1,TRAF5,FGD1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,SLC25A27,PHLPP1,ADAMTSL4,MERTK,LMNA,TFAP4,IGF1R,CYR61,DAPK1,MAP3K9,TNFRSF12A,MYDGF,PIM1,WNT3A,OXR1,ANO6,STRADB,SCRIB,IFIT3,PSMA4,G2E3,RASA1,CDK5R1,FAS,STK17A,SEMA4D,NFKBIA,AURKA,NR4A2,STK39,GDF11,MAP3K5,JAK3,RARG,IFI6,XDH,NQO1,THRA,INPP5D,RPS6KA1,PSME2,CAST,TP53,ERBB2,COL18A1,CD274,BCL2L1,AIFM2,PHLDA1,STIL,BCAP31,ARHGEF16,IER3,SP100,KIF14,BCL6,CDKN1B,DAB2IP,TWIST1,LGMN,EGLN3,CDKN2D,F2R,CTH,SIRT1,PPIF,RIPK2,AKT1,FIGNL1,HTATIP2,PRKCQ,SLC11A2,GLO1,CD40,MAP3K6,CASP4,SOCS3,IRS2,CDK19,STK26,NGFRAP1,BHLHB9,AXL,WFS1,TLE1,NRG1,IRF7,LIFR,BIN1,GCLM,ARHGEF3,PINK1,NKX3-1,CPEB4,ARHGEF11,DAP,PDIA3,PSMD10,SELL,TGFBR1,AES,GDF15,ETS1,GSTP1,BEX2,SIX4,TOP2A,CARD8,ADORA1,CTSC,PTEN,BMP7,TFAP2A,BAX,SGK3,SGK1,PLEKHF1,TMBIM6,BUB1,ERBB3,CITED2,FAIM,SPRY2,OSGIN1,RHOA,PSMB4,RAPGEF2,PLAUR,GCLC,PIK3R1,GRIN1,RGCC,PELI3,BCAR1,MAPK8IP1,GPLD1,FGFR2,SCG2,DHRS2,NR4A3,ARRB1,ITGAV,GPER1,OSR1,SOX8,ARHGEF9,HIPK3,MELK,ARHGEF4 |
| 5.199e-08 | -16.77 | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | 176 | 42 | 17758 | 1761 |
CCNE2,SPC25,DLGAP5,MRPS15,SLC25A13,NDC80,CCNB1,LMNA,FANCI,SAC3D1,TOP2A,APOBEC3B,RANBP1,NEK2,BUB1,MINPP1,NUP85,HMMR,PPIF,ZWINT,CENPA,KIF20A,ASPM,PBK,CDC20,PRKAR2B,GGH,NUSAP1,KIF11,LEPR,CDK1,PRDX4,AMMECR1,AURKA,STK39,MRPS28,UBE2C,CCNB2,ESPL1,E2F8,MELK,ACOT7 |
| 5.242e-08 | -16.76 | epithelium development | biological process | GO:0060429 | 979 | 152 | 16441 | 1675 |
EXPH5,EMX1,CASP3,LGR4,RET,EPHA4,MPP5,F11R,PLXNA1,PDGFB,SDC1,TMC1,PLS3,EPCAM,CYP1A1,CTGF,GRHL1,NPNT,ALDH1A3,MITF,ELF5,DLG1,TACSTD2,THRB,EZR,TFAP2C,LDB2,SAV1,CDK1,ARHGEF26,EDNRA,AGPAT2,PTER,TRAF3IP1,HDAC1,F2RL1,E2F8,GAB1,HOXC13,LGALS3,SERPINE2,SOX9,RAB23,NCKAP1,GPSM2,TNFRSF19,MECOM,ELF3,CA2,IGF1R,CYR61,MEGF8,FRAS1,FLRT3,WNT3A,SLC12A2,ALDH3A2,EPB41L5,KLK5,SALL4,SCRIB,NPHP3,NFIB,GNAS,ONECUT1,NCOA3,CSF1,KLK7,GDF11,SEMA3A,RARG,ADAMTS16,GRHL2,NF2,ST14,THRA,IQGAP1,TP53,COL18A1,PRKACA,DDR1,STIL,CCND1,PDGFA,SETDB2,LMO4,CDH3,TWIST1,PDE4D,DLG3,ETV4,DVL2,AKT1,DAG1,FZD7,SOCS3,ARHGAP35,BFSP1,SHROOM3,PTK7,OVOL1,NRG1,KLF5,LTA4H,COBL,CTHRC1,NKX3-1,FRMD6,LRP4,SDC4,CTSZ,CRABP2,HOXB2,FZD6,SIX4,PPP2R3A,ZDHHC21,CD109,CTNNBIP1,E2F7,BMP7,CST3,TFAP2A,BAX,TAGLN2,CITED2,SPRY2,MYO5A,TGIF1,HES1,RHOA,FMN1,RAPGEF2,PPARA,PRICKLE1,COL7A1,FNDC3A,PITX2,ARHGAP24,FAT4,FGFR2,ACVRL1,CTSV,TBX18,RAP2C,SPINT2,DBI,HOXB13,PLOD3,FZD5,SOX8,OSR1 |
| 5.245e-08 | -16.76 | cellular response to stimulus | biological process | GO:0051716 | 6201 | 733 | 16441 | 1675 |
ADD1,IL15RA,DNAJC3,RET,FBXO2,NRG2,IL18,MORF4L2,CA8,BARD1,CARD10,GRM5,CALM2,DAPK2,PSMD1,UBE2T,CYP2S1,KLF3,CLDN4,CRY2,SEMA3G,PIK3CD,TIAM1,TIPARP,TNIP1,CDA,PRKAR2B,CYP4F3,ARF4,ABR,PGF,ENPP1,CARHSP1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,GAB1,SCN5A,NUAK1,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ATG4A,TFAP4,MEGF8,RIMS3,FLRT3,FAM13B,RANBP1,MAP3K9,ALPK1,MYDGF,NCAM1,DGKG,NUP85,PAQR7,REC8,SALL4,STAT4,ERO1A,ELK1,NPHP3,PSMA4,GNA11,STK17A,PTPRF,NCOA3,SEMA4D,ITPR1,MDH1,STK39,GDF11,NDE1,ARPC2,NUP58,TMEM173,EGLN1,DOCK9,ARHGAP11A,NQO1,PAPSS2,INPP5D,ACTR8,CD82,PTTG1,NUF2,IL13RA1,GRK6,MGST2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,RTKN2,ARL4D,RAB27B,RASGEF1A,CDKN2D,MX1,SEC61B,RIPK2,FZD4,RAB38,XRCC6BP1,IRS2,ALDH3B1,CDK19,SHROOM3,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,NKX3-1,TNRC6C,SDC4,HABP4,RASSF7,BTN3A1,PDIA3,PKN1,PLPPR4,ETS1,GSTP1,TIPRL,PDIA4,SGPL1,CTNNBIP1,DTX3L,DIRAS3,CXCL16,ITGB8,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,PARP9,AMOTL2,OPLAH,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,NEURL1B,CNTNAP1,PLOD2,RAB11FIP2,NR1D2,ACVRL1,NR4A3,OSER1,ITGAV,CENPE,HMGA1,CMPK2,OSR1,USF2,WDR45B,MYL9,SIGIRR,BCAM,EPAS1,CUL4B,EPHA4,NDC80,LMCD1,NDRG2,DNAJB11,F11R,TEX2,ITPR2,HDAC6,PDGFB,SDC1,SPTB,FANCI,CPNE2,RPS6KA2,NPNT,SHC3,IL6ST,PAPSS1,MITF,DUSP10,SCARA3,PLK1,THRB,KCNIP3,MCTP1,CELSR2,NFE2L1,CR2,EZR,ARFRP1,PRKRA,SESN1,CDK1,RHEB,OPTN,DPYSL3,KDM4D,PLCH1,MAP2,WIPI1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,DNAJB2,HLA-F,RASA2,PDCL,RAB6A,NCKAP1,FBLN1,DHRS3,IL18R1,ANO1,IGF1R,KIF13B,SELK,MDFIC,AHCY,PIM1,WNT3A,PLCB2,CYP26B1,DPYSL5,RGMB,CORO2A,STRADB,EIF2AK1,TCF7,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,USP43,NF2,UGP2,FOXM1,XYLT1,TMX4,TP53,CCDC68,ERBB2,STIL,BCAP31,CYP26A1,IER3,RAD23A,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,NOTCH3,OAS3,SCN2A,EGLN3,CTDSP2,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,PTGER4,MYL12A,ATP13A2,DNAJC10,DUOX1,PTPRJ,IDE,ATP1A1,RBL1,PTK7,STK38,EFNA5,IRF7,ZMAT1,PINK1,CPEB4,CD63,ADGRG1,DAP,SWI5,CDCA8,GABRG2,PSMD10,GDF15,CRABP2,AIP,DNAJB9,FZD6,NRP2,PPP2R3A,M6PR,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,TSPAN13,KLF9,SYK,HES1,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,LITAF,PPARA,MAML2,PELI3,BCAR1,TXNDC11,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,FAT4,TWSG1,SCG2,NAT1,NMI,ICOSLG,NDFIP1,TBC1D4,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,PSME1,PLXNA1,CCNB1,PJA2,SLC20A1,CENPN,NCS1,CYP1A1,CTGF,ELMO2,IL31RA,FOSB,PIK3CA,IRF2,ATRNL1,TACSTD2,RCAN3,METAP2,SPATA18,ACVR1C,PBK,CASP9,SLC35C1,AGO4,PIF1,SAV1,ZFAND5,POR,PLK2,NKD1,EIF4EBP2,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,SLC1A3,TNFRSF19,TSPAN7,MESDC2,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,PPP4R1,PRKG1,OPN3,DAPK1,SORL1,CD70,TNFRSF12A,OSTF1,CACNA1D,PIKFYVE,MAST4,GPR161,RIMS2,SOCS5,EPB41L5,GFPT1,PRODH,DDB2,MICB,CALM1,AMER1,ANO6,EPHA1,ANTXR1,RASA1,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,MATN2,NR4A2,CABIN1,MAP3K5,IFIH1,EHD1,PLA2G4A,SPRED1,SLC2A4,REPS2,TCTN2,TRIP10,S100A11,THRA,RPS6KA1,IQGAP1,RALBP1,CD274,BCL2L1,DDR1,CYP39A1,EPS8L2,ZFYVE9,APLP2,NOV,ACAP2,DOK4,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,LGMN,TSPAN1,SULT2B1,MED30,NR2C1,SEMA3B,ATG4D,DOCK4,PRKCQ,SLC11A2,ATP1B1,PYGO1,RAD17,ASB13,ITPR3,ALCAM,FZD7,EPHA10,PPP2R5A,JAK1,STK26,NGFRAP1,TSPAN18,SLC27A1,NRG1,NR3C2,ARHGEF3,IGFBP6,DEPDC1,CENPI,EPS8,ARL4C,HERC5,FBXO6,EFNB1,FGF19,LGALS3BP,TEAD3,HLA-A,ADGRB2,RASSF8,E2F7,GNB5,PTEN,FUT8,CD9,SGK3,SLC44A2,ERBB3,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARAP2,SHMT1,ARHGEF28,ALDH2,ZWINT,MPP1,FURIN,PARP4,DIAPH2,YES1,FOS,GPLD1,TIMP3,FGFR2,RYK,GRIN2D,GPER1,LRRK1,FZD5,CPEB2,MELK,RGMA,LTBP1,CASP3,UGT8,CACNB4,DNER,KREMEN1,TRIM68,SH3KBP1,PTCHD4,HTR1D,EPCAM,ZFYVE16,RAB15,ZCCHC12,TSPAN6,DPYSL2,SIVA1,AKR1B1,RAB20,MYH14,CTTN,PTPRE,RASGRP1,SP5,CYP1B1,CENPA,TRIM8,ITCH,USP18,ARHGDIB,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,GPRC5B,MADD,CAB39,ADIPOR1,NRGN,RAP1GAP,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,ETV5,ASB9,CALM3,TEC,PHLPP1,CA2,COL6A1,DIAPH2-AS1,C10orf54,HLA-C,ZRANB1,CCDC88A,MDFI,ELK3,OXR1,PDE5A,FECH,GNAS,BCAR3,ONECUT1,PLPP3,NFKBIA,CDCA5,SH3BP4,RHOBTB2,YOD1,SHROOM2,JAK3,TOB1,RARG,COL16A1,GAS2L1,SLC25A24,SORBS1,SPC25,IL15,PSME2,PDIA5,IL27RA,MRAS,ARHGEF16,SS18,ARTN,CYP4F11,KIF14,TWIST1,DIXDC1,GOT1,PDIA6,F2R,FRS3,CHP1,MAP3K3,PTPRU,ERBB2IP,DUSP4,CD40,FANCE,DOCK5,MAP3K6,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,CYP2U1,LIFR,ABCA1,GCLM,SORT1,ARHGEF11,CIT,LRP4,TGFBR1,AES,NOTUM,HMGXB4,HDAC9,IL17RB,TOP2A,ADORA1,ADRBK1,BMP7,IQGAP3,MYO5A,RAB3B,NR4A1,DEPDC4,GCLC,RGCC,LEPR,ARHGAP24,CTSL,HLA-B,RND3,DHRS2,CTSV,RAP2C,DTX4,UACA,ARRB1,GEM,PLOD3,SOX8,L1CAM,AHR,CD33 |
| 5.303e-08 | -16.75 | GNF2_ESPL1 | MSigDB lists | GNF2_ESPL1 | 35 | 16 | 17758 | 1761 |
HMMR,PLK1,CENPA,KIF20A,FOXM1,ASPM,CDC20,CDCA8,KIF11,TOP2A,BUB1,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 5.334e-08 | -16.75 | single-multicellular organism process | biological process | GO:0044707 | 6192 | 732 | 16441 | 1675 |
HECA,ADD1,AK7,RET,HEXB,NRG2,IL18,BARD1,LTBP3,GRM5,CDKN2C,CALM2,WEE1,PSMD1,MUC4,PAQR5,ALDH1A3,KLF3,CLDN4,CRY2,PIK3CD,SEMA3G,TIAM1,TIPARP,ERAP2,SMARCA2,SPEF2,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,ITPKA,ARF6,HSPB1,GAB1,E2F8,HOXC13,SCN5A,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,RABGGTA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,NDUFA12,PAQR7,REC8,SALL4,NPHP3,TP53INP2,GNA11,PSMA4,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,ITPR1,CLMN,AURKA,STK39,GDF11,CFAP20,NDE1,DRP2,ARPC2,TMEM173,DOCK9,XDH,ADAMTS16,EGLN1,TPRN,PAPSS2,GRHL2,INPP5D,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,SCNN1A,CDH1,DACT1,RTKN2,ACSL4,DLG3,LRP11,RASGEF1A,CDKN2D,MYT1,SNX10,ETV4,SCN3A,ENPP4,SSH3,CAMSAP3,COL6A2,FZD4,SAT1,HTATIP2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,WFS1,AXL,CORO1C,SIPA1L1,PNPLA6,RGS14,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,DCAF7,SDC4,HABP4,BTN3A1,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,SGPL1,NEO1,CTNNBIP1,IGSF9,ITGB8,CALD1,CST3,BAX,ADAM15,TMBIM6,WWP1,SGCB,S100A6,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,SNTB1,CRISPLD2,CNTNAP1,PITX2,ACVRL1,RAB11FIP2,DBI,NR4A3,CENPE,ITGAV,FHL1,OSR1,USF2,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,ITPR2,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,MITF,PAPSS1,ELF5,TMEM143,DUSP10,NTN4,S100A13,NEB,THRB,CD55,KCNIP3,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,HS6ST1,KCNMB4,MAP2,HOXA9,PRKCDBP,MAFF,MYL12B,RUNX2,LGALS3,RASA2,PDCL,CNTNAP2,NCKAP1,FBLN1,DHRS3,IL18R1,ANO1,TNS3,DAZAP1,IGF1R,GATA2,FRAS1,KIF13B,PIM1,WNT3A,PLCB2,ALDH3A2,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,G2E3,PRX,CDK5R1,RASGRP2,MAPKAPK2,COL13A1,PHLPP2,ITGA7,CSF1,PRPS2,ATP1B3,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,P3H2,TP53,ERBB2,SLC7A2,STIL,EMP2,IER3,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,CDH3,ESPN,NOTCH3,SCN2A,MINPP1,LMAN1,GM2A,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,DUOX1,ATP1A1,IDE,PTPRJ,ABHD12,PTK7,ADAMTS14,IRF7,EFNA5,LTA4H,BIN1,COL9A3,CDH22,CD63,ADGRG1,SELL,GABRG2,PSMD10,CRABP2,FZD6,PPP2R3A,SIRPA,NRP2,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,ALDH7A1,SYK,TLE6,ATP2B1,GCNT1,HES1,RHOA,PSMB4,PLAUR,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BCAR1,RNPEP,BBS2,DGKE,PRDX4,FAT4,SERPINA1,SCG2,TWSG1,PGRMC1,PPP2R3C,GAA,LGR4,SSH1,HSPG2,VANGL1,ATP8A1,TMEM41B,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,PJA2,OAT,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,PIK3CA,IRF2,TACSTD2,ZBTB18,PACSIN1,LAMP2,SGCE,ACVR1C,CASP9,LDB2,CCNF,SAV1,ZFAND5,HLF,PLK2,NKD1,LRIG1,BMP1,DHTKD1,EIF4EBP2,SERPINI1,TANC2,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,CDKN1C,DGKQ,SLC25A27,KIF23,SLC1A3,HERC6,TNFRSF19,S100A2,KIAA1161,MECOM,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,OSTF1,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,EPB41L5,GFPT1,KCNJ12,MMD,CALM1,AMER1,ANO6,VEZT,EPHA1,NFIB,STX3,RASA1,FAS,DGKH,MMP15,GABRD,MATN2,FAM83D,PCDH19,NR4A2,PER3,HOOK1,EHD1,PLA2G4A,SPRED1,FOXO6,ST14,THRA,CAST,RPS6KA1,IQGAP1,BCL2L1,DDR1,MNS1,CYP39A1,NOV,APLP2,DOK4,CDKN1B,CNNM4,DAB2IP,EPHB4,PDE4D,LGMN,MED30,SEMA3B,GPX4,MYO5B,UTRN,PRKCQ,SLC11A2,PYGO1,ATP1B1,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,JAK1,NGFRAP1,NRG1,KLF5,PRR15,CBX7,COBL,WASF3,PCOLCE,HAPLN3,CENPI,EPS8,PBX3,SEPP1,SPR,EFNB1,FGF19,TEAD3,ADGRB2,SIX4,SNTA1,E2F7,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,CITED2,SPRY2,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,FURIN,C1GALT1C1,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,JARID2,RGMA,EXPH5,EMX1,CASP3,UGT8,CRYM,MPP5,CACNB4,DNER,TMC1,HTR1D,EPCAM,LRRC6,GRHL1,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,RP2,CTTN,MYH14,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,TRIM8,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,CA2,KCNN4,COL6A1,SUCO,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,OXR1,VWA1,HMG20B,PDE5A,BTN3A2,RANBP9,C3orf58,FECH,GNAS,BCAR3,ONECUT1,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,APOL2,COL16A1,RARG,KLF7,DYNLRB1,SORBS1,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,PHLDA1,SS18,SETDB2,ARTN,CYP4F11,FRYL,KIF14,DIXDC1,TWIST1,ECE1,F2R,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,SOCS3,ARHGAP35,ALDH5A1,BFSP1,BHLHB9,PEX2,PTBP3,TLE1,OVOL1,SPTBN5,ABCA1,LIFR,GCLM,ANXA3,SORT1,ARHGEF11,POC1B,CIT,LRP4,COL4A5,AES,TGFBR1,NTAN1,HDAC9,TOP2A,KIF5B,MDM1,ADRBK1,ADORA1,LLGL2,MYCL,BMP7,TOX2,RRBP1,KIAA0319,ARVCF,MYO5A,GCLC,NR4A1,ASPM,RC3H2,MBNL3,RGCC,TTC7A,RUNX3,FOXL1,LEPR,CTSL,ARHGAP24,SWAP70,PRCP,DHRS2,CTSV,SPINT2,ARRB1,HOXB13,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,ABCG1 |
| 5.367e-08 | -16.74 | MODULE_1 | MSigDB lists | MODULE_1 | 359 | 69 | 17758 | 1761 |
MYL9,LTBP1,BCAM,HSPG2,S100A11,IQGAP1,SDC1,EMP2,CHPF,IER3,CCND1,ST5,LMO4,MITF,FOSB,AOX1,BCL6,IFIT1,NOTCH3,LGMN,TIPARP,SMARCA2,SGCE,CD55,COL6A2,TIMP2,LHFPL2,OPTN,EDNRA,DPYSL3,MDK,PDLIM3,WFS1,MAFF,PCOLCE,CDKN1C,IGFBP6,ITGA6,EPS8,TRIB2,FBLN1,DHRS3,SEPP1,TSPAN7,LMNA,CYR61,CALD1,COL6A1,SGK1,ALDH7A1,IGFBP2,PIM1,CITED2,NCAM1,HES1,PRSS23,PLSCR1,NR4A1,FOS,FUCA1,PVRL2,DHRS2,ITGA7,ITPR1,TCEAL4,NR4A2,LTBP2,GEM,COL16A1 |
| 5.627e-08 | -16.69 | WHITFIELD_CELL_CYCLE_G2_M | MSigDB lists | WHITFIELD_CELL_CYCLE_G2_M | 202 | 46 | 17758 | 1761 |
DEPDC1,DLGAP5,FOXM1,VANGL1,CKAP2,CIT,NUF2,GRK6,LBR,LMNA,KIF5B,SS18,KIF14,NEK2,SLC44A2,GOT1,BUB1,KLF9,PIK3CD,RASGEF1A,ZMYM1,CDKN2D,CCDC88A,CKS2,SEPHS1,HMMR,PLK1,TGIF1,CENPA,PBK,PTPN9,CDC20,HMG20B,ARHGDIB,NUSAP1,DUSP4,ANLN,KCTD2,G2E3,FAM64A,MATN2,ITPR1,AURKA,CENPE,NDE1,CCNB2 |
| 5.670e-08 | -16.69 | localization of cell | biological process | GO:0051674 | 853 | 136 | 16441 | 1675 |
EPHA4,HEXB,RET,F11R,PDGFB,SDC1,DNER,SH3KBP1,LRRC6,CTGF,ELMO2,MITF,PIK3CA,SEMA3G,PIK3CD,CTTN,TIAM1,CYP1B1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,MDK,PLCG1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,S100A2,MERTK,TNS3,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PRKG1,TNFRSF12A,ZRANB1,NUP85,CCDC88A,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,PLD1,ATP1B3,NDE1,SHROOM2,JAK3,SEMA3A,INPP5D,EMP2,APC2,DDR1,ARHGEF16,NOV,ARTN,LHX6,DIXDC1,TWIST1,DAB2IP,EPHB4,PDE4D,RASGEF1A,TSPAN1,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,JAK1,AXL,PTK7,CORO1C,PEX2,NRG1,CTHRC1,ADGRG1,CD63,SDC4,EPS8,SELL,TGFBR1,PKN1,DNAH3,ETS1,FGF19,EFNB1,SRPX2,SIX4,SIRPA,SGPL1,CXCL16,PTEN,FUT8,KIAA0319,BAX,SYK,GCNT1,PARP9,HES1,RHOA,CFAP46,RAPGEF2,NR4A1,ASPM,PIK3R1,YES1,BCAR1,GPLD1,ARHGAP24,PITX2,ACVRL1,SCG2,ITGAV,SOX8,ARSB,L1CAM |
| 5.670e-08 | -16.69 | cell motility | biological process | GO:0048870 | 853 | 136 | 16441 | 1675 |
RET,EPHA4,HEXB,F11R,PDGFB,DNER,SDC1,SH3KBP1,LRRC6,CTGF,ELMO2,MITF,PIK3CA,PIK3CD,CTTN,SEMA3G,TIAM1,CYP1B1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,MDK,PLCG1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,S100A2,MERTK,TNS3,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PRKG1,TNFRSF12A,ZRANB1,NUP85,CCDC88A,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,ATP1B3,PLD1,NDE1,SHROOM2,SEMA3A,JAK3,INPP5D,EMP2,APC2,DDR1,ARHGEF16,NOV,ARTN,LHX6,DIXDC1,TWIST1,DAB2IP,EPHB4,PDE4D,RASGEF1A,TSPAN1,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,JAK1,AXL,CORO1C,PTK7,PEX2,NRG1,CTHRC1,CD63,ADGRG1,SDC4,EPS8,SELL,TGFBR1,PKN1,DNAH3,ETS1,SRPX2,FGF19,EFNB1,SIX4,SIRPA,SGPL1,CXCL16,PTEN,FUT8,KIAA0319,BAX,SYK,GCNT1,PARP9,HES1,RHOA,CFAP46,NR4A1,RAPGEF2,ASPM,PIK3R1,YES1,BCAR1,GPLD1,PITX2,ARHGAP24,SCG2,ACVRL1,ITGAV,SOX8,ARSB,L1CAM |
| 5.799e-08 | -16.66 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 393 | 75 | 16441 | 1675 |
SPRED1,NF2,NLRX1,FOXM1,NDRG2,BCL2L1,NOV,DACT1,RGS3,TSPAN6,BCL6,DLG1,DUSP10,DAB2IP,TWIST1,CDKN2D,CHP1,SIRT1,PPIF,TIMP2,TNIP1,AKT1,FIGNL1,ITCH,PBK,EZR,ERBB2IP,DUSP4,DAG1,OPTN,ARHGAP35,PTPRJ,WFS1,STK38,PRKCDBP,TLE1,RGS14,F2RL1,HSPB1,PRKAA2,ARAP3,PINK1,SERPINE2,NUAK1,RASA2,PSMD10,PHLPP1,FBLN1,GSTP1,MECOM,CARD8,ITGA3,IGF1R,PTEN,BMP7,SORL1,TMBIM6,SPRY2,RHOA,PLAUR,LITAF,STMN3,RANBP9,MAPK8IP1,RASA1,G2E3,ARHGAP24,BANK1,NFKBIA,ITPR1,SH3BP4,ARRB1,GPER1,HIPK3,XDH |
| 5.848e-08 | -16.65 | response to organic substance | biological process | GO:0010033 | 2656 | 349 | 16441 | 1675 |
SSH1,ADD1,IL15RA,DNAJC3,RET,FBXO2,NRG2,PSME1,IL18,CCNB1,CALM2,CYP1A1,SESN3,PSMD1,CTGF,IL31RA,KLF3,FOSB,STEAP2,PIK3CA,CLDN4,IRF2,MANF,PIK3CD,TIAM1,TIPARP,ACVR1C,CASP9,AGO4,PRKAR2B,F12,POR,ABR,PIAS3,ENPP1,PLCG1,NOD2,HDAC1,EIF4EBP2,HSPB1,GAB1,FGD1,DDX58,HLA-E,DGKQ,SOX9,TNFRSF19,LMNA,TFAP4,ITGA3,MEGF8,FLRT3,DAPK1,CD70,TNFRSF12A,MYDGF,NCAM1,NUP85,SOCS5,PAQR7,EPB41L5,GFPT1,STAT4,MICB,CALM1,ERO1A,ELK1,PSMA4,RASA1,FAS,MMP15,NCOA3,PRKAG2,ITPR1,AURKA,NR4A2,NUP58,TMEM173,EHD1,SPRED1,SLC2A4,NQO1,THRA,RPS6KA1,IQGAP1,IL13RA1,BCL2L1,CD274,PRKACA,ZFYVE9,CCND1,ACAP2,CDH1,SP100,CDKN1B,DAB2IP,PDE4D,IFIT1,ACSL4,RASGEF1A,CDKN2D,NR2C1,MX1,SEC61B,COL6A2,RIPK2,FZD4,PRKCQ,SLC11A2,ITPR3,FZD7,IRS2,JAK1,DDOST,CDK19,NGFRAP1,WFS1,AXL,SLC27A1,NRG1,NR3C2,MAPK12,ARHGEF3,NKX3-1,TNRC6C,EPS8,HERC5,FBXO6,ETS1,GSTP1,FGF19,HLA-A,CXCL16,CTSC,PTEN,CST3,FUT8,BAX,CD9,TMBIM6,IGFBP2,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,NCOA2,RASGRF1,TGIF1,PDGFC,SHMT1,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,FURIN,YES1,FOS,GPLD1,PITX2,TIMP3,PLOD2,FGFR2,RAB11FIP2,NR1D2,ACVRL1,NR4A3,GRIN2D,GPER1,CMPK2,FZD5,OSR1,ARSB,CPEB2,RGMA,CASP3,UGT8,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,SDC1,TRIM68,SPTB,ZFYVE16,RPS6KA2,NPNT,SHC3,ZCCHC12,IL6ST,DPYSL2,ABCA2,AKR1B1,DUSP10,RASGRP1,SP5,CYP1B1,THRB,TRIM8,CITED4,USP18,EZR,PRKRA,IDH1,RHEB,DPYSL3,MDK,WIPI1,MAP2,MADD,CAB39,ADIPOR1,NR2C2,PCSK5,RRAGD,PRKAA2,GRN,RUNX2,HLA-F,RASA2,DNAJB2,CALM3,PHLPP1,IL18R1,IGF1R,CA2,GATA2,COL6A1,PIM1,C10orf54,HLA-C,WNT3A,RGMB,STRADB,TCF7,PDK3,IFIT3,FECH,GNAS,MAPKAPK2,PHLPP2,CSF1,NFKBIA,SH3BP4,YOD1,LTBP2,JAK3,IFI6,RARG,COL16A1,GAS2L1,SORBS1,IL15,FOXM1,PSME2,PDIA5,TP53,ERBB2,IL27RA,ARHGEF16,PDGFA,ATP6V0B,PLCG2,SRR,TWIST1,GOT1,OAS3,PDIA6,F2R,CTDSP2,FRS3,CTH,SIRT1,TIMP2,ERLEC1,AKT1,PTPRU,PTGER4,ERBB2IP,DUSP4,CD40,DAG1,CASP4,SOCS3,DUOX1,DNAJC10,ATP1A1,IDE,RBL1,PTK7,IRF7,SPTBN5,LTA4H,LIFR,ABCA1,ANXA3,SORT1,CPEB4,ARHGEF11,LRP4,PSMD10,SELL,GABRG2,TGFBR1,GDF15,AES,DNAJB9,NRP2,HDAC9,IL17RB,ADRBK1,BMP7,TOX2,UBE2J1,TFAP2A,TRIM21,KLF9,IQGAP3,SYK,MYO5A,GCNT1,RHOA,PSMB4,NR3C1,IFITM3,NR4A1,GCLC,AMFR,LITAF,PPARA,GGH,RUNX3,BBS2,BCAR1,LEPR,CD83,CTSL,HLA-B,TWSG1,CTSV,HOXB13,PLOD3,TBC1D4,PTGES,ARHGEF9,ABCG1,ARHGEF4 |
| 5.913e-08 | -16.64 | extracellular region part | cellular component | GO:0044421 | 3764 | 465 | 17570 | 1756 |
LAMP1,GAA,TXN,KLK10,HSPG2,IL15RA,ATP8A1,DNAJC3,HEXB,PPFIBP2,FBXO2,NRG2,PSME1,IL18,LYNX1,NANS,PLXNA1,VASH1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,CTGF,CABP1,ALDH1A3,SERINC2,AOX1,TACSTD2,MTMR11,SEMA3G,TINAGL1,ZBTB18,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,PRKAR2B,LOXL2,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,ENPP1,CARHSP1,PTER,BMP1,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,ITGA6,HLA-E,RAB23,KIF23,NDUFA4,SLC1A3,MERTK,TTYH3,GNS,DOPEY2,ITGA3,CYR61,SNX18,LYPD3,ATP5H,MEGF8,RPL39,VASN,FLRT3,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,ULBP2,C9orf72,RIMS2,GFPT1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,PSMA4,GNA11,STX3,CYB5A,FRMD4B,FAS,PTPRF,SCARB2,NCOA3,PRKAG2,SLC4A4,SEMA4D,MATN2,MDH1,KLK7,MAL2,GDF11,ARPC2,CFAP20,SERPINB1,XDH,ADAMTS16,EHD1,MTM1,SLC2A4,NQO1,ST14,TRIP10,S100A11,BROX,CD82,IQGAP1,FTH1,KCTD12,CD274,MVB12B,AIFM2,PRKACA,DDR1,TNFSF9,TMPRSS4,EPS8L2,NOV,APLP2,MUC16,SCNN1A,CDH1,DAB2IP,ACSL4,EPHB4,TSPAN1,DLG3,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,COL6A2,FZD4,SYNE2,CYS1,LYRM1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,SP4,CMTM7,EPHA10,ALDH3B1,STK26,AXL,NRG1,ISOC1,WASF3,CTHRC1,PCOLCE,IGFBP6,HAPLN3,EPS8,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,SRPX2,EFNB1,LGALS3BP,HLA-A,WWP2,CXCL16,FUT2,ITGB8,CTSC,ARSG,MGAT4A,CST3,FJX1,FUT8,CD9,BAX,ADAM15,SLC44A2,WWP1,IGFBP2,ERBB3,TAGLN2,S100A6,CRTAP,PVRL4,ADAMTS2,PDGFC,ALDH2,SHMT1,B3GNT2,PLSCR1,FURIN,PARP4,C1GALT1C1,AK4,BLVRA,YES1,AIF1L,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,ACOT7,CYBRD1,RGMA,LTBP1,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,LMCD1,NDRG2,F11R,NENF,MPP5,PDGFB,SDC1,ERP29,SUSD2,EPCAM,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,RBBP8NL,DLG1,AKR1B1,NTN4,RP2,MYH14,CTTN,NEB,S100A13,THRB,NLRP4,CD55,ITCH,CR2,EZR,KLK6,ARHGDIB,IDH1,CDK1,RHEB,DPYSL3,KDM4D,ZNF114,GPRC5B,UEVLD,CAB39,ARRDC1,GLA,MYL12B,CAPN1,CPPED1,PCSK5,GRN,PRSS8,LASP1,FAM213B,LGALS3,SERPINE2,FXYD3,CALM3,ASAH1,PM20D2,RAB6A,NCKAP1,FBLN1,ADAMTSL4,ANO1,CA2,FRAS1,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,C3orf58,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,PLPP3,CSF1,PRPS2,SH3BP4,FAM213A,EGFL7,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,SEMA3A,COL16A1,PROM2,UGP2,IL15,P3H2,PSME2,CTDSPL,HDAC11,COL18A1,MRAS,PDGFA,ARTN,EFR3A,PLCG2,VAT1,GOT1,ECE1,OAS3,MINPP1,LMAN1,PDIA6,GM2A,CTH,CHP1,SULF2,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,IGSF8,GLO1,ERBB2IP,CD40,MYL12A,DAG1,IDE,ATP1A1,PTPRJ,BHLHB9,MMP17,SECTM1,ADAMTS14,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,CMTM4,MAN2B2,COL9A3,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,CDCA8,GDF15,COL4A5,CRABP2,VPS26A,DNAJB9,SIRPA,TMEM63A,CD109,IRF2BPL,TAF1B,MLPH,A4GALT,BMP7,GALNS,FAM63A,ALDH7A1,ATP2B1,MYO5A,GCNT1,FAH,SYPL1,PGM1,RAB3B,RHOA,FBLN5,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,GGH,RNPEP,SCRN2,PRDX4,ENDOD1,FUCA1,CTSL,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,SCG2,PRCP,DHRS2,CTSV,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,TBC1D4,CD33 |
| 6.037e-08 | -16.62 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | 128 | 34 | 17758 | 1761 |
CCNE2,RMND5A,KIAA1462,PPP1R2,CDKN1C,FOXM1,CTDSPL,PTTG1,NDC80,CCNB1,SEPP1,EMP2,LBR,TOP2A,ADD3,CYP1A1,REEP1,BUB1,IGFBP2,BTBD3,SMAGP,LAMP3,PLK1,MYBL2,LDB2,KIF11,CDK1,TIMP3,PDLIM3,GPRC5B,UNC5B,CCNB2,UBE2C,GAB1 |
| 6.048e-08 | -16.62 | GSE22886_CTRL_VS_LPS_24H_DC_DN | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_DN | 196 | 45 | 17758 | 1761 |
DDX58,CASP3,TXN,IL15RA,VANGL1,PSME2,HLA-E,HLA-F,TAP1,CALM3,HERC5,BTN3A1,SAMD9,HERC6,LGALS3BP,HLA-A,H1FX,CALM2,BTG3,TYMP,IFIT1,OAS3,RASGRP1,GPX4,LAMP3,TGIF1,SEC61B,RIPK2,TNIP1,IFITM3,USP18,CALM1,NFE2L1,PTGER4,BTN3A2,PRKAR2B,IFIT3,CD83,HLA-B,C19orf66,NMI,NR4A3,IRF7,IFIH1,IFI6 |
| 6.146e-08 | -16.60 | ENK_UV_RESPONSE_EPIDERMIS_UP | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_UP | 276 | 57 | 17758 | 1761 |
ANXA3,GCLM,CMAS,SLC25A13,RGS20,PKP2,PRSS22,MPP5,FTH1,BCL2L1,GRK6,ETS1,TMPRSS4,PSIP1,ELF3,M6PR,CA2,ITGA3,FUT2,PRICKLE3,IL6ST,ALDH1A3,DAPK1,FXYD5,SORL1,TUBG1,CDH3,MTMR11,MANF,ULBP2,MYLIP,MDFI,SNX7,MX1,DDB2,PLSCR1,IFITM3,CYB5R2,CDC20,ARHGDIB,F12,TP53I3,PRIM1,PGF,CARHSP1,SERPINA1,HPSE,CSF1,CSTF2,HDAC1,NRG1,IRF7,STK39,RAP1GAP,SERPINB1,ESPL1,KLF7 |
| 6.474e-08 | -16.55 | GSE3982_MAST_CELL_VS_DC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_DC_DN | 190 | 44 | 17758 | 1761 |
GAS2L1,SORT1,LRRFIP2,NFKBIE,IL15,GALNT12,SDC4,FAM134A,RAB23,IL13RA1,FAM198B,NANS,VASH1,BARD1,PPP2R3A,EPCAM,CA2,IGF1R,RAB20,TACSTD2,CTTN,SYK,RBMS2,CKAP4,LAMP3,GUSB,ADCK3,DIAPH2,PRKAR2B,ALCAM,GNA11,CYB5A,RHEB,DNAJC10,ACADSB,WIPI1,C19orf66,OTUB2,CLIP4,MDH1,RGS14,RAP1GAP,ARSB,ACOT7 |
| 6.474e-08 | -16.55 | LTE2_UP.V1_DN | MSigDB lists | LTE2_UP.V1_DN | 190 | 44 | 17758 | 1761 |
DDX58,ANXA3,COL9A3,PARP12,LGR4,CALB2,TAP1,HERC5,SAMD9,HERC6,LGALS3BP,SYTL2,BTG3,ADD3,IGF1R,SP100,ALG13,BHLHE41,TFAP2A,IFIT1,OAS3,LAMP3,GCA,HES1,ZNF84,PLSCR1,PRSS23,MICB,LPGAT1,USP18,PRKAR2B,DNAJB14,IFIT3,MDK,PDLIM3,PTER,AMMECR1,MATN2,NMI,IRF7,GEM,IFIH1,PTGES,IFI6 |
| 6.510e-08 | -16.55 | ZHAN_MULTIPLE_MYELOMA_PR_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_PR_UP | 44 | 18 | 17758 | 1761 |
SPC25,DLGAP5,FOXM1,ASPM,CCDC34,NUSAP1,NUF2,CCNB1,CDK1,FANCI,TOP2A,UBE2T,KIF14,NEK2,AURKA,CCNB2,UBE2C,E2F8 |
| 6.658e-08 | -16.52 | Golgi membrane | cellular component | GO:0000139 | 665 | 110 | 17570 | 1756 |
SLC35D2,IL15RA,GALNT12,ATP2C2,XYLT1,ARFGEF1,FAM198B,MGAT5B,PJA2,EMP2,PDGFB,APC2,BCAP31,SLC9A7,NCS1,CHPF,PDGFA,AP1M2,CABP1,XYLT2,STEAP2,FUT1,NOTCH3,LMAN1,SCARA3,MGAT5,RASGRP1,CHP1,ATL1,SEC23A,CLCN3,COG2,SLC35C1,KIF13A,PKMYT1,GALNT7,MCFD2,RHEB,OPTN,MAN2A2,TAPBP,HS6ST1,STK26,WIPI1,GNPTAB,ATP7B,HS3ST3B1,NRGN,RAP1GAP,ST3GAL1,NDST3,SORT1,LMTK3,GOLIM4,SCOC,HLA-E,HLA-F,CTSZ,RAB6A,POMGNT1,B4GALT4,DSE,HLA-A,PARM1,B4GALNT1,ZDHHC21,B3GALNT1,DOPEY2,FUT2,CTSC,A4GALT,MGAT4A,FUT8,FAM20B,TPST1,HLA-C,PIKFYVE,NCAM1,PPP6R1,MPHOSPH9,KDELR1,GCNT1,B3GALT6,CHSY3,PDGFC,B3GNT7,B3GNT2,SYBU,MGAT4B,GYLTL1B,FURIN,C1GALT1C1,COL7A1,FNDC3A,C3orf58,GLCE,GNAS,GALNT3,HLA-B,NUCB1,SERPINA1,RND3,ARRB1,ZDHHC7,GPER1,PLD1,FZD5,NDFIP1,ABCG1,GOLGB1 |
| 6.716e-08 | -16.52 | CTTTAAR_UNKNOWN | MSigDB lists | CTTTAAR_UNKNOWN | 918 | 141 | 17758 | 1761 |
EPAS1,FBXO2,LMCD1,VASH1,SH3KBP1,CDKN2C,SIPA1L2,RAB15,ELMO2,IMPAD1,DPYSL2,KLF3,MITF,SLC44A1,DLG1,STEAP2,AKR1B1,ATRNL1,DUSP10,THRB,TNIP1,CELSR2,ACVR1C,SERTAD4,CBX6,PRKAR2B,PIF1,PPP1R14C,LDB2,IDH1,ANKRD10,MAP2,ZNF367,PIK3C2B,NFKBIZ,UNC5B,NRGN,F2RL1,HOXC13,NR2C2,CHCHD7,FXYD3,ETV5,SLC1A3,TNFRSF19,BMP2K,LMNA,MECOM,ITGA3,CYR61,ZNRF2,BHLHE41,FAM13B,PPP4R1,OPN3,AHCY,RFX5,CACNA1D,RIMS2,EPB41L5,CYP26B1,HPS3,MGAT4B,HMG20B,TCF7,EPHA1,PDIK1L,MUM1L1,XKRX,MMP15,PELI2,RHOBTB2,SEMA3A,TOB1,SPRED1,NCKAP5,SORBS1,SLC2A4,FAM92A1,HOXB7,CAST,OSR2,PRKACA,ZFYVE9,APLP2,LMO4,VAT1,DAB2IP,DLG3,EGLN3,ZNF365,SEMA3B,SEPHS1,CPD,SSH3,ERBB2IP,NFIX,ATP1A1,MMP17,AXL,SLC9A6,KLF5,PRIMA1,C1orf43,REEP4,NDST3,NR3C2,CMTM4,BIN1,PACSIN2,HAPLN3,MACC1,ARL4C,PBX3,SRPX2,PPP2R3A,SCML1,FOXP2,CTNNBIP1,MDM1,ADD3,CDK16,LYPD6,MGAT4A,FUT8,FAM20B,TOX2,TAGLN2,C12orf75,MED22,GCNT1,TGIF1,BCL9,PITX2,HLA-B,NUCB1,ABCB1,OTUB2,ZBTB33,SNPH,JARID2 |
| 6.781e-08 | -16.51 | GSE6269_HEALTHY_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 40 | 17758 | 1761 |
GRN,SEMA6B,SORT1,LGALS3,S100A11,CD63,BLVRB,FTH1,DSE,PRRG4,SIRPA,APLP2,RAB20,MARCH2,CDKN2D,CKAP4,PPIF,CPD,LAMP2,TIMP2,MPP1,PLAUR,NPC2,RNF19B,ZFAND5,ARF4,RHEB,SOCS3,HPSE,SERPINA1,H1F0,PELI2,NOD2,ADIPOR1,NRG1,HS3ST3B1,PLIN3,SERPINB1,CYBRD1,RRAGD |
| 6.899e-08 | -16.49 | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 184 | 43 | 17758 | 1761 |
PARP12,IL15,C5orf30,RAB23,HERC5,CD274,HERC6,DNAH3,PRRG4,TMCC3,EPDR1,SP100,TRANK1,ITGB8,DRAM1,TWIST1,TSPAN13,IFIT1,OAS3,APOBEC3G,CKAP4,MX1,ARAP2,MICB,USP18,NUB1,C3orf52,GGH,RUNX3,IFIT3,CYB5A,UEVLD,C19orf66,TRIM69,NLRC5,NR4A3,AGFG2,NFKBIZ,IRF7,CMPK2,IFIH1,CPEB2,MELK |
| 6.899e-08 | -16.49 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 184 | 43 | 17758 | 1761 |
CD99,GCLM,IL15,VANGL1,CAST,EFHD2,BCL2L1,WWP2,CTSC,SLC16A6,RGS3,OSBPL3,PLCG2,PPP4R1,ABCA2,MDFIC,RASGEF1A,DLG3,MYBL1,C12orf75,APOBEC3G,SYTL3,SNTB2,S100A4,ITCH,SYNE2,UTRN,RUNX3,PIF1,BLVRA,FAS,ARHGAP35,OPTN,GALNT3,PTPRJ,WIPI1,SERPINI1,MAP3K5,ARF6,SLC27A3,GLCCI1,CPEB2,STARD3NL |
| 7.098e-08 | -16.46 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 197 | 45 | 17758 | 1761 |
SUN1,MAN2B2,SIGIRR,ZNF395,CAST,ATP8A1,INPP5D,SELL,HMGN3,INTS8,MGST2,ERP29,ADD3,FAM46A,METTL7A,ZFP36,LMO4,CST3,SORL1,RFX5,MTMR11,PIK3CD,CNPY3,PLCB2,PGM1,ALDH2,ADCK3,S100A4,CDA,FOS,CRISPLD2,RASGRP2,FUCA1,PELI2,STK38,SECTM1,CCDC69,CLMN,ZDHHC7,KLF11,PIEZO1,NRGN,LTA4H,CPPED1,CD33 |
| 7.111e-08 | -16.46 | HORIUCHI_WTAP_TARGETS_UP | MSigDB lists | HORIUCHI_WTAP_TARGETS_UP | 284 | 58 | 17758 | 1761 |
MYL9,GLIS3,ALDH6A1,SERPINE2,SSH1,HOXB7,IL15,DNAJB2,SDC4,ASAH1,ITPR2,TRIB2,BEX2,SH3KBP1,LGALS3BP,MESDC2,DIRAS3,CD109,CXCL16,SIPA1L2,OPN3,ANKRD12,LIMCH1,LRIF1,MYLIP,LAMP3,GFPT1,ATL1,PCGF5,SPATA18,NR3C1,OSTM1,HTATIP2,SLC11A2,LRRC1,DUSP4,IFIT3,PTGFRN,PCTP,ENDOD1,NUDT16,TAPBP,H1F0,ANKRD6,NR1D2,PRCP,BHLHB9,CSF1,ITPR1,ERAP1,ARRB1,PIK3C2B,TANC2,PER3,GLCCI1,IFIH1,ABCA1,CPPED1 |
| 7.117e-08 | -16.46 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1862 | 252 | 17758 | 1761 |
VANGL1,TSC22D3,ATP8A1,ARFGEF1,NDRG2,TEX2,VARS2,MPP5,F11R,MORF4L2,VASH1,FAM101B,SDC1,LTBP3,KREMEN1,CHPF,CALM2,NKAIN3,RAB15,SESN3,HSF2,SHC3,DPYSL2,RGS3,PRICKLE3,TSPAN6,MKRN3,SLC44A1,MITF,ELF5,KLF3,SERINC2,KCNS3,ANKRD12,ATRNL1,CLDN4,PIK3CD,MYH14,ANO4,TIAM1,BTBD3,CYP1B1,SMARCA2,SH3BGRL,SERTAD4,PRKAR2B,ROR1,LDB2,PTGFRN,ZFAND5,COL12A1,DPYSL3,PGF,CXXC4,MDK,ANKRD10,HS6ST1,PLCG1,ARHGEF19,GPRC5B,KLF12,WIPI1,MAP2,PLK2,HOXA9,NKD1,TMOD2,SERPINI1,LEMD1,RRAGD,LASP1,CDK17,CDKN1C,ZCCHC24,CALM3,RAB6A,FAM81A,FBLN1,TFAP4,IGF1R,FRY,CYR61,GATA2,VASN,FLRT3,FRAS1,PPP4R1,DAPK1,PIM1,WNT3A,MAST4,GAD1,CKAP4,GPR161,SOCS5,DPYSL5,ELK3,PCDH1,MMD,KIF20A,TBC1D8B,CALM1,GYLTL1B,NPC2,TP53INP2,NFIB,C3orf58,RANBP9,G2E3,CDK5R1,BCAR3,FECH,AP1AR,PVRL2,H1F0,SLC2A6,ALPK3,NR4A2,ATP1B3,MAP3K5,SEMA3A,TOB1,AFAP1,RARG,KLF7,EHD1,CCNE2,NCKAP5,CCDC109B,GRHL2,HOXB7,TP53,KCTD12,IL13RA1,FAM198B,BCL2L1,SNN,APC2,DDR1,CCND1,SS18,ST5,RNF220,DACT1,LMO4,LHX6,REEP1,BCL6,VAT1,CDH3,GLB1L2,RTKN2,DAB2IP,NOTCH3,PDE4D,DLG3,ETV4,MYT1,F2R,SCN3A,DOCK4,CAPN6,SLC39A8,LYRM1,PANK1,ATP1B1,PYGO1,ERBB2IP,DUSP4,ITPR3,SP4,FZD7,NFIX,NIN,PTPRJ,CCDC149,PTK7,EFNA5,NRG1,C1orf43,NR3C2,GLIS3,IER5L,CTHRC1,SORT1,IGFBP6,EPS8,ARL4C,GABRG2,PBX3,TGFBR1,PKN1,TRIB2,HOXB2,EFNB1,SIX4,HMGXB4,NRP2,PPP2R3A,NEO1,SCML1,WWP2,CCDC92,CTNNBIP1,FOXP2,AKIRIN1,MDM1,ADD3,ADORA1,ITGB8,CALD1,LYPD6,FUT8,FJX1,TOX2,TFAP2A,SGK3,MAPK11,TSPAN13,ERBB3,CITED2,SPRY2,SUN2,TGIF1,PDGFC,PSMB4,BCL9,PIK3R1,GRIN1,CCDC34,STMN3,FOS,ARHGAP24,PITX2,RND3,PLOD2,PRCP,RAP2C,NR4A3,GRIN2D,PPP2R3C,HMGA1,FHL1,CEP41,OSR1,ZMIZ1,NDFIP1,L1CAM,ZBTB33,PKIA,ARHGEF4,RGMA |
| 7.363e-08 | -16.42 | ERBB signaling pathway | biological process | GO:0038127 | 325 | 65 | 16441 | 1675 |
SPRED1,REPS2,PSME2,IQGAP1,NRG2,ERBB2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,SH3KBP1,PDGFA,CALM2,PSMD1,SHC3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKAR2B,AGO4,ERBB2IP,ITPR3,ARF4,IRS2,PLCG1,JAK1,NRG1,SPTBN5,GAB1,TNRC6C,RASA2,EPS8,SOX9,PSMD10,CALM3,PHLPP1,FGF19,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,SOCS5,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,PSMA4,RASA1,FGFR2,PHLPP2,ITPR1,GRIN2D,JAK3 |
| 7.804e-08 | -16.37 | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | MSigDB lists | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | 348 | 67 | 17758 | 1761 |
UPF3B,DLGAP5,FOXM1,HEXB,PPFIBP2,NDC80,IL13RA1,NUF2,CCNB1,PHLDA1,CCND1,SESN3,UBE2T,TSPAN6,OSBPL3,TINAGL1,PHKA2,SCARA3,S100A13,LAMP2,PLK1,SMARCA2,PBK,USP18,CDC20,NUSAP1,ATP1B1,ANLN,SESN1,ATP10D,BHLHB9,GLA,GLCCI1,GRN,PARP12,ENO2,SDC4,BLVRB,ABCG2,HOXB2,LGALS3BP,NEO1,FOXP2,TOP2A,RNF128,NEK2,FXYD5,ALDH7A1,IGFBP2,RFX5,HLA-C,SLC12A2,HMMR,PGM1,ALDH2,KIF20A,IFITM3,RNF113A,NFIB,PTPRF,FUCA1,SCARB2,PLOD2,LTBP2,OSR1,ESPL1,MELK |
| 7.882e-08 | -16.36 | GNF2_BUB1B | MSigDB lists | GNF2_BUB1B | 49 | 19 | 17758 | 1761 |
HMMR,PLK1,ZWINT,HJURP,KIF20A,ASPM,CDC20,NDC80,CDCA8,KIF11,FANCI,TOP2A,KIF14,AURKA,BUB1,CCNB2,UBE2C,ESPL1,MELK |
| 8.072e-08 | -16.33 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | 518 | 90 | 17758 | 1761 |
AVPI1,CCDC109B,SORBS1,IL15RA,NQO1,FLYWCH2,TMEM41B,LYNX1,CD274,FAM198B,SLC20A1,CENPN,CMTM6,LTBP3,ABCD4,CHPF,NOV,BTG3,CTGF,SHC3,PHTF1,FOSB,ENPP5,HYLS1,TINAGL1,PACSIN1,CDKN2D,NEB,SP5,TIMP2,S100A4,COQ10B,SAT1,UTRN,HTATIP2,C15orf39,MCFD2,MFAP3L,ALDH3B1,PTK7,WFS1,FAM114A1,BMP1,SP6,NFKBIZ,ANXA3,SERPINE2,FRMD6,RAB23,ASB9,ASAH1,COL4A5,FBXO6,ETS1,ANO1,TEAD3,BMP2K,AKIRIN1,RALGPS2,RNF128,IGF1R,RINL,VASN,DRAM1,TNFRSF12A,TSPAN13,ALDH3A2,S100A6,AMOTL2,FADS2,ZWINT,PRSS23,NR4A1,PLAUR,BCL9,C1GALT1C1,COL7A1,YES1,ANTXR1,GNA11,MAPK8IP1,FAS,FUCA1,TJP3,CGREF1,NMI,ALPK3,SFMBT1,CTSA,XDH |
| 8.091e-08 | -16.33 | GSE6269_HEALTHY_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STREP_PNEUMO_INF_PBMC_DN | 166 | 40 | 17758 | 1761 |
GRN,MYL9,COL9A3,SORT1,LGALS3,ARHGEF11,CD63,CAST,BLVRB,IL13RA1,SIRPA,GNS,CTNNBIP1,APLP2,BCL6,MARCH2,CRTAP,CKAP4,CYP1B1,CPD,PPIF,LAMP2,TIMP2,PLAUR,FURIN,CDA,MCFD2,RNF19B,FOS,SOCS3,H1F0,FGFR2,PELI2,ADIPOR1,ANXA9,ZMIZ1,PLIN3,SERPINB1,CYBRD1,CD33 |
| 8.103e-08 | -16.33 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 16152 | 1654 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,DDOST,POPDC3,NGFRAP1,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,PDIA6,F2R,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,DHRS2,OTUB2,SOX8,GEM,L1CAM,SNPH |
| 8.670e-08 | -16.26 | LIU_VMYB_TARGETS_UP | MSigDB lists | LIU_VMYB_TARGETS_UP | 118 | 32 | 17758 | 1761 |
FAM134A,ARL4C,ABCG2,PHLPP1,NUCB2,CA8,PSIP1,H1FX,SAC3D1,IL17RB,RPS6KA2,GNB5,DPYSL2,LHX6,KCNS3,ALDH7A1,EPB41L4B,MPHOSPH9,SNX7,ARAP2,PLSCR1,MMD,HSPA12A,PRKAR2B,ALCAM,FZD7,STK17A,MAPKAPK2,RBM47,NMI,KLF11,NXT2 |
| 8.940e-08 | -16.23 | TBK1.DF_UP | MSigDB lists | TBK1.DF_UP | 272 | 56 | 17758 | 1761 |
CCDC109B,ARAP3,NF2,NFKBIE,ENO2,TMEM41B,GALNT12,RGS20,CCDC68,TEX2,CRABP2,NUP62CL,SIRPA,PPP2R3A,FZD6,ZFYVE16,BTG3,TNS3,IGF1R,RGS3,PASK,OPN3,TPST1,CNNM4,CLDN4,PIK3CD,EPB41L4B,MINPP1,DLG3,MYBL1,SNX10,MAST4,IGSF3,FAM69A,TRAK2,GCA,SLC37A1,OSTM1,PLAUR,C3orf52,PIP4K2C,C1GALT1C1,PCTP,TP53I3,ATP10D,STEAP1,STX3,ABR,CD83,ENDOD1,SWAP70,PTK7,NETO2,KLF11,ITGAV,CYBRD1 |
| 8.948e-08 | -16.23 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | 192 | 44 | 17758 | 1761 |
GRN,SERPINE2,FRMD6,TSC22D3,SELL,IL27RA,HMGN3,SYTL4,CAMK1D,GPSM2,ITPR2,PHLPP1,DHRS3,LTBP3,SYTL2,TMEM63A,CDKN2C,RPS6KA2,IL6ST,BCL6,MDFIC,KLF9,EPB41L4B,HLA-C,ERBB3,RCAN3,SUN2,PQLC3,MPP1,PCBP3,FOXJ2,ATP1B1,RAB38,ALCAM,CASP4,HLA-B,SCARB2,GPRC5B,HOXA9,SERPINI1,ANXA9,RELL1,ISOC1,ABCA1 |
| 8.948e-08 | -16.23 | GSE29618_MONOCYTE_VS_PDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_UP | 192 | 44 | 17758 | 1761 |
LGALS3,IL15,S100A11,HEBP1,CAST,HLA-F,BLVRB,ASAH1,CALM3,EFHD2,FAM198B,OAT,ARHGEF40,SIRPA,IER3,CALM2,APLP2,FAM46A,BCL6,RAB20,MTMR11,ALDH3A2,CKAP4,CYP1B1,PPIF,TIMP2,S100A4,CALM1,ARHGDIB,BLVRA,RNF19B,CRISPLD2,KLHL2,IRS2,ALDH3B1,SLC6A6,SERPINA1,HPSE,C19orf66,NOD2,ZDHHC7,KLF11,CD33,PCSK5 |
| 9.110e-08 | -16.21 | HOELZEL_NF1_TARGETS_UP | MSigDB lists | HOELZEL_NF1_TARGETS_UP | 130 | 34 | 17758 | 1761 |
LGALS3,FAM199X,EPS8,CYB561,GDF15,NUP62CL,PHLDA1,S100A2,PLS3,PDGFA,SESN3,FAM46A,SLC27A6,OSBPL3,DRAM1,GAD1,CAPN6,SEPT6,DUSP4,STK17B,FAS,GNAS,ENDOD1,PDLIM3,SCG2,RND3,ACVRL1,MAP2,PLK2,TSPAN18,FAM114A1,NRG1,HS3ST3B1,NXT2 |
| 9.120e-08 | -16.21 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | 90 | 27 | 17758 | 1761 |
EPB41L5,LMO7,BMF,HPS3,EPAS1,NR3C1,SALL4,NUAK1,UTRN,PTGER4,ERBB2,NPHP3,ALCAM,CRISPLD2,TNS3,SESN3,NPNT,N4BP3,AIM1,ZNF704,DRAM1,SH3BP4,ZDHHC7,UACA,EGLN3,RAB27B,PARP9 |
| 9.587e-08 | -16.16 | GSE2706_UNSTIM_VS_8H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_DN | 186 | 43 | 17758 | 1761 |
DDX58,TXN,ARMCX3,IL15,MACC1,HERC5,CD274,HERC6,SLC9A7,BTG3,SESN3,ITGB8,GRHL1,OSBPL3,CD70,IFIT1,TINAGL1,ARL4D,RASGRP1,IGSF3,PARP9,USP18,STAT4,RAPGEF2,LYRM1,SAT1,PTGER4,DUSP4,IFIT3,SOCS3,DGKH,ARHGAP24,SWAP70,SHROOM3,TRIM69,SIPA1L1,NMI,NLRC5,NR4A3,NFKBIZ,CMPK2,IFIH1,IFI6 |
| 9.945e-08 | -16.12 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 17176 | 1732 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,RNF224,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.021e-07 | -16.10 | AAAYWAACM_V$HFH4_01 | MSigDB lists | AAAYWAACM_V$HFH4_01 | 239 | 51 | 17758 | 1761 |
REPS2,CAST,FAM134A,SYTL2,NEO1,FOXP2,HSF2,ITGA3,RALGPS2,GRHL1,CYR61,CALD1,BMP7,VASN,FLRT3,BDH1,KLF3,FOSB,MITF,SLC44A1,BCL6,FAM63A,SGK1,TACSTD2,TSPAN13,CRY2,IQGAP3,SCN2A,NCAM1,MYLIP,MAP3K3,NFE2L3,SMARCA2,TRIM8,SPATA18,SLC39A8,SNTB2,RGAG1,H2AFV,IDH1,PRX,NFIX,KLF12,HOXA9,NKD1,NR4A3,ADAMTS14,REEP4,SEMA3A,MAFF,KLF7 |
| 1.034e-07 | -16.08 | axonogenesis | biological process | GO:0007409 | 674 | 112 | 16441 | 1675 |
MYL9,SPRED1,PSME2,RPS6KA1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,ARTN,SHC3,DPYSL2,DLG1,TRPC1,DAB2IP,NTN4,MYH14,EPHB4,RASGEF1A,DLG3,TIAM1,ETV4,RASGRP1,FRS3,SEMA3B,ATL1,COL6A2,EZR,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,DPYSL3,EPHA10,IRS2,PLCG1,JAK1,MAP2,LIMK1,SLC9A6,SPTBN5,NRG1,EFNA5,UNC5B,COBL,MYL12B,SCN5A,COL9A3,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,PLPPR4,FGF19,EFNB1,NRP2,NEO1,KIF5B,IGF1R,PTEN,BMP7,FLRT3,COL6A1,ERBB3,CACNA1D,NCAM1,WNT3A,S100A6,FARP2,DPYSL5,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,RANBP9,PSMA4,NFIB,CDK5R1,RASA1,CNTNAP1,FGFR2,SEMA4D,MATN2,RYK,NR4A3,PGRMC1,PITPNA,GRIN2D,NR4A2,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 1.050e-07 | -16.07 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | 193 | 44 | 17758 | 1761 |
CMAS,ADD1,LGALS3,S100A11,GNPDA1,CAST,DAP,ARL4C,SELL,FTH1,CRABP2,OAT,IL18R1,FGF19,PLS3,GNB5,IL6ST,TWIST1,TACSTD2,ALDH7A1,AHCY,TAGLN2,S100A6,GCNT1,SUN2,S100A4,CBX6,FURIN,ARHGDIB,ALCAM,CYB5A,GABARAPL1,ONECUT1,RPL12,CDCA7L,AURKA,GEM,TMEM159,JAK3,E2F8,AHR,KLF7,JARID2,EHD1 |
| 1.114e-07 | -16.01 | BENPORATH_PROLIFERATION | MSigDB lists | BENPORATH_PROLIFERATION | 137 | 35 | 17758 | 1761 |
S100A11,PTTG1,NDC80,NUF2,GPSM2,CENPN,LBR,NCS1,APOBEC3B,TOP2A,UBE2T,RANBP1,NEK2,BUB1,CKS2,NFE2L3,CENPA,PSMB4,ASPM,PBK,MYBL2,PKMYT1,ANLN,H2AFV,FANCE,SLC25A5,CDK1,CSNK1G1,CDCA5,NMI,AURKA,CENPE,TMEM14A,CCNB2,RRAGD |
| 1.115e-07 | -16.01 | ONDER_CDH1_TARGETS_1_UP | MSigDB lists | ONDER_CDH1_TARGETS_1_UP | 131 | 34 | 17758 | 1761 |
PRSS8,ALDH6A1,IL15,TSC22D3,INPP5D,FBXO2,GDF15,DNAJB9,H1FX,CYP4F11,METTL7A,BHLHE41,LHX6,BCL6,CDKN1B,CD70,IGFBP2,KLF9,CTTN,CTH,CYP1B1,GFPT1,CD55,CELSR2,ADCK3,GCLC,LEPR,CYP4F3,GABARAPL1,PRKAG2,NR1D2,WIPI1,FAM117A,ABCG1 |
| 1.129e-07 | -16.00 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4353 | 521 | 17775 | 1757 |
AASS,SLC25A13,DNAJC3,RET,CACNA2D2,NRG2,MORF4L2,BARD1,GRM5,CALM2,CDKN2C,DAPK2,PSMD1,CYP2S1,PIK3CD,TIAM1,ERAP2,SPEF2,TNIP1,SH3BGRL,CDA,TFAP2C,PRKAR2B,LOXL2,PPP1R14C,COL12A1,PLCG1,DNM1L,LIMK1,NOD2,HDAC1,ARF6,GAB1,FAM169A,ITGA6,SOX9,SLC36A4,GPSM2,MERTK,ATG4A,MARCH8,FRY,FAM189A1,RIMS3,MAP3K9,CADPS2,NCAM1,MYLIP,DGKG,NUP85,MCCC2,KIF20A,SALL4,STAT4,MYBL2,PCTP,DCP2,CYB5A,STK17A,DHX32,PTPRF,CACHD1,NCOA3,ITPR1,XDH,EGLN1,DOCK9,GRHL2,PAPSS2,ACTR8,PKP2,TESK2,APC2,REPS1,ZNF385B,APPBP2,CDS1,MUC16,RNF220,SCNN1A,CDH1,SP100,RASGEF1A,SCN3A,MX1,PTPN9,SYNE2,CDCA2,RAB38,IRS2,SHROOM3,CDK19,WFS1,SIPA1L1,INPP4B,PLEKHG1,TTC8,HABP4,SDC4,ANO9,PKN1,PLPPR4,ETS1,SLC25A43,SRPX2,NEO1,PDIA4,SLC27A6,ANKS1B,CTSC,FAM20B,KLC3,FAM102A,WWP1,NPTXR,SGCB,AMOTL2,ADAMTS2,LCA5,PLSCR1,FAM160A1,TACC1,RAPGEF2,PIK3R1,EIF5A2,CXorf57,UBE2A,SNTB1,CNTNAP1,RPL12,PLOD2,SYT7,NR1D2,PPM1H,ITGAV,FHL1,DCBLD1,TLL2,BCAM,EPAS1,EPHA4,CUL4B,LMCD1,ITPR2,SDC1,SPTB,BTG3,SHC3,PAPSS1,MITF,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,SMAGP,ZNF462,THRB,MCTP1,KCNIP3,CELSR2,ANLN,IDH1,DPYSL3,KLF12,MAP2,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,RRAGD,FXYD3,RAB6A,CNTNAP2,NCKAP1,B4GALT4,TNS3,IGF1R,FRAS1,MDFIC,PIM1,WNT3A,ABCC1,CHSY3,PCDH1,CORO2A,SPATA13,IFIT3,ANKRD29,PRX,P4HA3,PLD1,SEMA3A,USP43,CTDSPL,TMX4,XYLT1,TP53,ERBB2,STIL,TTC21B,LMO4,PLCG2,BCL6,CDH3,GLB1L2,NOTCH3,SULF2,CLCN3,TMTC1,MBP,AKT1,DAG1,IDE,ABHD12,PTK7,ADAMTS14,EFNA5,NDST3,CMTM4,BIN1,GOLIM4,CDH22,GABRG2,DSE,SLC9A2,NRP2,SH2D4A,FZD6,ZDHHC21,CD109,FOXP2,UBE2J1,SGK1,BUB1,IGDCC4,NFE2L3,DLGAP1,RHOA,PSMB4,NR3C1,MAML2,PELI3,FNDC3A,TXNDC11,DGKE,CD83,BANK1,SERPINA1,FAT4,SCG2,ZNF214,SH3BGRL2,TBC1D4,PTGES,HIPK3,ARHGEF4,SLC35D2,PPP4R4,HSPG2,LGR4,VANGL1,ATP8A1,PSME1,VASH1,SLC20A1,TYMP,SESN3,ZNF823,STIM1,ELMO2,PIK3CA,STEAP2,SERINC2,ATRNL1,RCAN3,LOC81691,ORAI2,SNTB2,CASP9,HSPA12A,KIF13A,GALNT7,CCNF,LDB2,ANKRD10,BMP1,PRDM5,EIF4EBP2,NFKBIZ,TANC2,DDX58,CDK17,FRMD4A,CDKN1C,TBC1D1,C6orf106,SLC1A3,TNFRSF19,TSPAN7,PRRG4,DOPEY2,ITGA3,RALGPS2,PIK3AP1,LYPD3,BDH1,PRKG1,RUNDC3B,SORL1,OSTF1,CD70,CACNA1D,PIKFYVE,GPR161,RIMS2,TRAK2,FAM69A,GFPT1,EPB41L5,FADS2,TBC1D8B,LPGAT1,ANTXR1,NFIB,RASA1,STX3,FAS,DGKH,PLEKHH2,PRKAG2,TJP3,FAAH,ISM1,PELI2,SFMBT1,PCDH19,PER3,MAP3K5,IFIH1,HOOK1,EHD1,FRMPD3,PLA2G4A,SPRED1,SLC2A4,DLGAP5,S100A11,ST14,IQGAP1,RPS6KA1,CCDC110,ATP2C2,CYP39A1,MNS1,ZFYVE9,NOV,EPHB4,IFIT1,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PANK1,UTRN,TMEM144,PRKCQ,SP4,PRDM11,NIN,EPHA10,PPP2R5A,ZNF704,NRG1,MLKL,NR3C2,COBL,DENND5B,WASF3,CENPI,ATP9A,EPS8,PBX3,LGALS3BP,WWP2,RNF128,PTEN,FUT8,ERBB3,CNOT6L,NCOA2,FARP2,PDGFC,RASGRF1,ARAP2,ARHGEF28,ZC3H11A,DIAPH2,LRRC1,GRTP1,KIF11,ARSK,GPLD1,TBX18,ABCB1,PGM2L1,GRIN2D,ETAA1,ARSB,ESPL1,OCLN,JARID2,EXPH5,LTBP1,DNER,TRIM68,TMC1,SH3KBP1,NKAIN3,ZFYVE16,ARHGEF10L,SIPA1L2,HSF2,ARHGEF37,TSPAN6,IMPAD1,ANKFN1,DLG1,TRPC1,POF1B,SUN3,RAB20,CTTN,BTBD3,MYRIP,PTPRE,TRIM8,ITCH,RGAG1,ROR1,EDNRA,MAN2A2,NR2C2,PCSK5,ARAP3,ABCG2,SAMD9,PHLPP1,ADAMTSL4,ZNF432,OTUD1,COL6A1,LIMCH1,HLA-C,NCEH1,SLC12A2,GAD1,ETV7,ELK3,PDE5A,HEATR5A,PDIK1L,NUBP1,XKRX,ONECUT1,TMEM30A,UTP14C,NFKBIA,ALPK3,JAK3,KLF7,LMO7,NCKAP5,PSME2,PDIA5,MRAS,ZNF687,FRYL,RPN2,EPB41L4B,PDIA6,MAP3K3,ZNF525,DUSP4,DOCK5,TLE1,VSIG10,SPTBN5,LIFR,LNP1,SORT1,ARHGEF11,TGFBR1,TRMT2B,FAM167A,TMEM63A,IL17RB,KIF5B,CARD8,ADRBK1,MLPH,BMP7,RRBP1,TOX2,KIAA0319,MYO5A,SYPL1,PGM1,ASPM,MBNL3,OGDHL,TTC7A,KLHL2,HLA-B,SWAP70,RND3,TRIM69,AHR,RAB3IL1 |
| 1.137e-07 | -15.99 | GSE14350_IL2RB_KO_VS_WT_TREG_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_DN | 200 | 45 | 17758 | 1761 |
HECA,CCDC109B,SERPINE2,LGALS3,CKAP2,DAP,SDC4,MMADHC,NDRG2,HMGN3,ADAMTSL4,REPS1,HDAC9,EPCAM,APOBEC3B,CDKN2C,CTGF,KCNN4,TSPAN6,OSBPL3,SORL1,NTN4,ELK3,S100A4,SAT1,CBX6,SESN1,ALCAM,CD83,DGKH,PTPRJ,SWAP70,TWSG1,H1F0,ANKRD6,AXL,PELI2,SERPINB6,EPB41L4A,GLCCI1,F2RL1,L1CAM,RRAGD,MAPK12,XDH |
| 1.154e-07 | -15.98 | GNF2_CKS2 | MSigDB lists | GNF2_CKS2 | 50 | 19 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,KIF20A,FOXM1,CKAP2,ASPM,PTTG1,CDC20,NDC80,NUSAP1,CDK1,FANCI,TOP2A,PLK4,CENPE,CCNB2,CKS2,METAP2 |
| 1.176e-07 | -15.96 | GGGAGGRR_V$MAZ_Q6 | MSigDB lists | GGGAGGRR_V$MAZ_Q6 | 2165 | 285 | 17758 | 1761 |
HSPG2,VANGL1,TSC22D3,IL18,NCS1,SESN3,CTGF,RGS3,CABP1,FOSB,SERINC2,KCNS3,CLDN4,MANF,TINAGL1,LAMP2,SMARCA2,TMEM151A,TFAP2C,PRKAR2B,TNS1,KIF13A,ARF4,COL12A1,PIAS3,GDE1,BMP1,HDAC1,SERPINI1,ITPKA,ARF6,HSPB1,E2F8,HOXC13,FGD1,SCN5A,MRC2,CDK17,TSPAN7,HPCAL4,PSIP1,LMNA,RABGGTA,MECOM,TFAP4,ITGA3,PIK3AP1,SLC16A6,VASN,BHLHE41,TNFRSF12A,NCAM1,DGKG,KLK5,MMD,EPHA1,GNA11,PTPRF,MMP15,NCOA3,ITPR1,AGBL5,MDH1,ARMCX3,GRHL2,REPS2,TRIP10,THRA,FTH1,GRK6,APC2,PRKACA,CCND1,ST5,RNF220,SCNN1A,FAM46A,XYLT2,DAB2IP,DLG3,ETV4,MYT1,SULT2B1,GPX4,DOCK4,SYNE2,PANK1,KIF1C,RAD17,RAB38,ALCAM,SNX12,SP4,FZD7,NFIX,NIN,PDLIM3,NGFRAP1,NRG1,SLC27A3,PRR15,MAPK12,PCOLCE,IGFBP6,ARL4C,PBX3,PKN1,HOXB2,EFNB1,SIX4,TEAD3,NEO1,WWP2,TMCC3,CTNNBIP1,AKIRIN1,ADD3,ITGB8,CALD1,FUT8,ADAM15,ERBB3,NCOA2,TGIF1,BCL9,GRIN1,FURIN,C2orf69,FOS,PITX2,RPL12,SYT7,NR4A3,CCDC69,GRIN2D,HMGA1,FZD5,CYBRD1,OCLN,JARID2,RGMA,BCAM,EPAS1,PPM1J,ARFGEF1,NDRG2,TP53I11,PDGFB,SDC1,DENND2D,CHPF,PLS3,NKAIN3,MITF,SLC44A1,THRB,ZNF462,ATL1,TRIM8,CBX6,ROR1,SESN1,ZBTB7B,IDH1,KDM4D,MDK,ARHGEF19,KLF12,HOXA9,PRKCDBP,ADIPOR1,SP6,GLA,GRN,PRSS8,LASP1,ARAP3,PARP12,BMF,ZNF395,CHCHD7,FXYD3,PYROXD2,ETV5,CNTNAP2,ADAMTSL4,B4GALNT1,AIM1L,DAZAP1,IGF1R,KCNN4,RFX5,PIM1,PLCB2,KDELR1,MDFI,PCDH1,PLEKHA6,ELK3,GYLTL1B,HMG20B,VWA1,C3orf58,MUM1L1,RASGRP2,FOXD2,BCAR3,GNAS,H1F0,PVRL2,NFKBIA,RHOBTB2,SHROOM2,TOB1,RARG,CCNE2,NCKAP5,SORBS1,UGP2,HOXB7,CTDSPL,HDAC11,TP53,COL18A1,CYP26A1,ZNF687,ARTN,LMO4,LHX6,VAT1,GOT1,EPB41L4B,NOTCH3,LMAN1,SULF2,FRS3,MAP3K3,S100A4,SERTAD3,IGSF8,DUSP4,MAP3K6,ATP1A1,PTPRJ,PTK7,VSIG10,EFNA5,ANXA9,C1orf43,ST3GAL1,ABCA1,POC1B,BLVRB,FAM134A,MIER3,GABRG2,GDF15,COL4A5,TRMT2B,TRIB2,AIP,SLC9A2,H1FX,M6PR,IRF2BPL,CD109,CDK16,BMP7,ARVCF,CLIP2,PHF20L1,HES1,RHOA,PLAUR,RUNX3,PELI3,TCEAL8,ARHGAP24,HNRNPH2,PRCP,RAP2C,FAM117A,GEM,NDFIP1,SNPH |
| 1.179e-07 | -15.95 | human chrXq24 | chromosome location | human chrXq24 | 48 | 16 | 26250 | 1887 |
LAMP2,LONRF3,UPF3B,SEPT6,UBE2A,C1GALT1C1,NKRF,IL13RA1,RNF113A,SLC25A43,SOWAHD,SLC25A5,ZCCHC12,WDR44,RPL39,NKAPP1 |
| 1.198e-07 | -15.94 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 359 | 68 | 17758 | 1761 |
PAPSS2,CRYM,TSC22D3,DNAJC3,CUL4B,SLC20A1,PHLDA1,SYTL2,CDH1,IL6ST,TSPAN6,PLCG2,SLC44A1,TMEM37,TSPAN1,LMAN1,LAMP2,SMARCA2,CD55,SEPT6,CYS1,SAT1,RBM47,CDK19,PTER,FAM110C,SLC27A1,NFKBIZ,GLCCI1,RAP1GAP,MAFF,RRAGD,IER5L,HLA-E,ETV5,SLC25A27,GDF15,SEPP1,DHRS3,SLC25A36,CARD8,FAM189A1,MGAT4A,ALG13,FLRT3,AIM1,MAST4,SPRY2,TPCN1,HES1,ZC3H11A,PIK3R1,ZNF320,BTN3A2,AK4,STMN3,PDK3,SNTB1,ANTXR1,FOS,ANKRD29,GALNT3,SERPINA1,PLOD2,TMC5,ARRB1,JAK3,SERPINB1 |
| 1.252e-07 | -15.89 | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 156 | 38 | 17758 | 1761 |
NKX3-1,NFKBIE,ZNF395,IL27RA,TRIB2,SLC20A1,PHLDA1,DNAJB9,IER3,BTG3,TNS3,FAM46A,KCNN4,FLRT3,IL6ST,FJX1,BCL6,TPST1,DUSP10,CITED2,TIPARP,PPIF,PLAUR,C3orf52,LITAF,PTGER4,COL7A1,ALCAM,FZD7,PITX2,TAPBP,PLK2,HOXA9,FGD6,AURKA,ITGAV,TOB1,MAFF |
| 1.313e-07 | -15.85 | RTAAACA_V$FREAC2_01 | MSigDB lists | RTAAACA_V$FREAC2_01 | 871 | 134 | 17758 | 1761 |
TRIM2,HSPG2,TSC22D3,ARFGEF1,DHX8,NDRG2,CAMK1D,PDGFB,CMTM6,PLS3,WEE1,SESN3,HSF2,CTGF,GRHL1,MKRN3,IL6ST,KLF3,MITF,DUSP10,BTBD3,TIAM1,METAP2,SMARCA2,TRIM8,ING1,TNIP1,ACVR1C,SERTAD4,RGAG1,ROR1,SLC25A5,MDK,TRIM9,KLF12,EIF4EBP2,LEMD1,MAFF,PCSK5,RMND5A,LASP1,FRMD4A,CDKN1C,CHCHD7,ETV5,ASAH1,PHLPP1,DHRS3,TNFRSF19,MECOM,TFAP4,IGF1R,FRY,RALGPS2,CYR61,SLC16A6,FLRT3,VASN,ZRANB1,PLCB2,KCNJ12,ELK3,KIF20A,ADCK3,MGAT4B,TCF7,NFIB,RANBP9,DCP2,PLEKHH2,TIMM8A,KBTBD2,PELI2,MATN2,NR4A2,IFIH1,TOB1,RARG,EGLN1,SLC2A4,THRA,ERBB2,KCTD12,GRK6,OSR2,PRKACA,ZFYVE9,ZNF385B,CCND1,LMO4,CDKN1B,DAB2IP,MYT1,CTH,PANK1,DUSP4,DOCK5,NFIX,NIN,PDLIM3,AXL,TLE1,NRG1,C1orf43,REEP4,LIFR,ABCA1,BIN1,IGFBP6,FAM134A,ETS1,SEPP1,PPP2R3A,NEO1,CD109,FOXP2,RNF128,CALD1,BUB1,KLF9,CITED2,CLIP2,TGIF1,PDGFC,NR3C1,NR4A1,LRRC1,FOS,PITX2,GALNT3,ABCB1,OSR1,PKIA,OCLN |
| 1.324e-07 | -15.84 | GSE27786_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKCELL_DN | 188 | 43 | 17758 | 1761 |
CASP3,LRP4,BLVRB,HEXB,C6orf106,DHRS3,VPS26A,ATP6V0B,E2F7,MDM1,CA2,OSBPL3,IL31RA,PAPSS1,ALPK1,ARL4D,SCARA3,CNPY3,SNX10,SPRY2,HES1,GUSB,MPP1,ITCH,NUSAP1,ANLN,PCTP,ARSK,NFIX,MAPKAPK2,SLC6A6,RBM47,PPP2R5A,DBI,ADIPOR1,NFKBIZ,LRRK1,MLKL,GEM,MAP3K5,ARSB,JARID2,NXT2 |
| 1.329e-07 | -15.83 | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | MSigDB lists | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | 144 | 36 | 17758 | 1761 |
CASP3,TTC39B,GNPDA1,TBC1D1,TSC22D3,FAM102B,BCL2L1,FAM101B,DHRS3,IL17RB,CDH1,DACT1,KLF3,BCL6,RAB27B,TIAM1,SLC12A2,SYTL3,PGM1,PHF20L1,PCGF5,SLC39A8,STAT4,FURIN,DUSP4,SNTB1,STK17B,CD83,NCOA3,CSF1,SPINT2,CDCA7L,NR4A3,NFKBIZ,SERPINB6,RRAGD |
| 1.335e-07 | -15.83 | PH | pfam domains | PF00169 | 177 | 42 | 16629 | 1696 |
ARAP3,CIT,RASA2,TEC,SBF1,PHLPP1,ARHGEF16,SNTA1,ACAP2,ADRBK1,RALGPS2,PLEKHF1,RTKN2,CADPS2,TIAM1,FARP2,RASGRF1,PLEKHA6,ARAP2,AKT1,PLEKHO1,SPATA13,SNTB1,ANLN,ADRBK2,ABR,RASA1,ARHGAP24,IRS2,DGKH,SWAP70,PLEKHH2,TRIOBP,FGD6,PLD1,AFAP1,GAB1,ARHGEF9,DEF6,DOCK9,ARHGEF4,FGD1 |
| 1.362e-07 | -15.81 | GGGYGTGNY_UNKNOWN | MSigDB lists | GGGYGTGNY_UNKNOWN | 632 | 104 | 17758 | 1761 |
CCNI,NCKAP5,SLC2A4,AVPI1,CCDC109B,CAMKK1,IQGAP1,CAST,THRA,RALBP1,TMX4,ARFGEF1,NRG2,MORF4L2,GRK6,VASH1,DENND2D,TSEN34,SH3KBP1,APLP2,WEE1,PSMD1,FAM46A,WDR44,TSPAN6,DPYSL2,RGS3,FOSB,MITF,FUT1,TMEM143,POF1B,VAT1,EPB41L4B,ARMCX6,SMYD5,ETV4,GPX4,SEMA3B,LAMP2,ATL1,AKT1,FOXJ2,RNF19B,MYL12A,ATP10D,ABR,MDK,ATP1A1,PTK7,DOLPP1,ATP7B,ZNF367,OVOL1,KLF5,RGS14,FGD1,CDK17,PARP12,LGALS3,ALDH6A1,FXYD3,ADCK5,HMGN3,TRIB2,EFNB1,TFAP4,ITGA3,FRY,RALGPS2,PIK3AP1,CDK16,KCNN4,FAM20B,FAM13B,NCAM1,NCOA2,CCDC88A,IGDCC4,TRAK2,DPYSL5,ACBD5,NR3C1,MGAT4B,STRADB,PDIK1L,TP53INP2,CRISPLD2,PRX,DCP2,NUCB1,NCOA3,SLCO4A1,COL13A1,FGFR2,UTP14C,DBI,RAP2C,NR4A3,FAM117A,FHL1,OSR1,RARG,DOCK9 |
| 1.368e-07 | -15.80 | WANG_SMARCE1_TARGETS_DN | MSigDB lists | WANG_SMARCE1_TARGETS_DN | 353 | 67 | 17758 | 1761 |
CCNE2,PPP4R4,TAP1,NDC80,RGS20,RNF182,FAM198B,KBTBD11,FANCI,AKR1B1,TWIST1,NTN4,RP2,OAS3,MYBL1,CYP1B1,MX1,PPIF,TRIM8,SLC39A8,OSTM1,PBK,DRAP1,PTGER4,GALNT7,DUSP4,GTF2A2,TRIM9,PDLIM3,HPSE,PLK2,INPP4B,NRG1,GLA,PARP12,GDF15,ISYNA1,S100A2,LBR,BMP2K,LGALS3BP,SAC3D1,SCML1,B3GALNT1,CTSC,FJX1,CD9,OPN3,SGK1,TSPAN13,CD70,HLA-C,CITED2,ATP2B1,FADS2,PRSS23,MRS2,GRTP1,RASA1,HLA-B,SLCO4A1,SCG2,DCK,AURKA,HMGA1,SPCS3,TBC1D4 |
| 1.368e-07 | -15.80 | MODULE_12 | MSigDB lists | MODULE_12 | 353 | 67 | 17758 | 1761 |
MYL9,UGT8,TRIM2,HSPG2,S100A11,THRA,CCND1,LMO4,FOSB,BCL6,GOT1,IFIT1,NOTCH3,CYP1B1,SGCE,MBP,COL6A2,SLC11A2,KLK6,ALCAM,LHFPL2,DPYSL3,GPRC5B,TLE1,SERPINI1,PIK3C2B,BIN1,COL9A3,WASF3,PCOLCE,CDKN1C,IGFBP6,ENO2,ITGA6,DNAJB2,ATP9A,SOX9,ASAH1,CYB561,SLC1A3,TRIB2,SEPP1,FBLN1,DHRS3,TSPAN7,TMEM63A,CYR61,COL6A1,IGFBP2,ALDH7A1,ERBB3,NCAM1,HES1,FADS2,NR4A1,GRIN1,FOS,TIMP3,SLC4A4,ITGA7,TCEAL4,DTX4,CDK18,STK39,L1CAM,COL16A1,ARHGEF4 |
| 1.437e-07 | -15.76 | GSE7460_TCONV_VS_TREG_THYMUS_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_DN | 195 | 44 | 17758 | 1761 |
CCDC109B,LGALS3,CHCHD7,S100A11,NCKAP1,PHLPP1,IL18R1,NRP2,ITGB8,FAM46A,OSBPL3,KIAA0319,TSPAN13,NTN4,MDFIC,KLF9,PIM1,SNX10,MGAT5,S100A6,IGSF3,CHSY3,TGIF1,ELK3,PLSCR1,PTPN9,CORO2A,S100A4,PTGER4,DUSP4,PRKRA,CD40,PCTP,RNPEP,CASP4,CD83,GABARAPL1,HLA-B,PRKAG2,KCNK1,PTER,SH3BGRL2,AHR,ACOT7 |
| 1.449e-07 | -15.75 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 479 | 84 | 17758 | 1761 |
SLC2A4,S100A11,GALNT12,TSC22D3,SLC25A13,FHDC1,PKP2,COL18A1,IL13RA1,NENF,MGAT5B,AIFM2,EMP2,CARD10,DAPK2,EPCAM,N4BP3,ALDH1A3,SLC44A1,ZDHHC23,ABCA2,ESPN,PACSIN1,PTPRE,RASGRP1,SMAGP,MYO5B,CAMSAP3,MBP,SERTAD4,CYS1,LOXL2,ITPR3,ADRBK2,COL12A1,ABR,PGF,POPDC3,MLKL,PRIMA1,SYT13,ITPKA,RAP1GAP,SLC27A3,COL9A3,PARP12,NKX3-1,CDKN1C,ATP9A,CALB2,CYB561,PM20D2,C11orf95,ADAMTSL4,PRRG4,FZD6,RAVER2,SNTA1,C16orf74,PIK3AP1,LLGL2,BMP7,ARVCF,TAGLN2,NFE2L3,SLC37A1,LPGAT1,VWA1,TCF7,GRTP1,MAPK8IP1,SEMA4D,H1F0,MFSD2A,NMI,SLC2A6,SPINT2,SLC4A3,GRIN2D,LRRK1,HMGA1,CCNB2,COL16A1,TLL2 |
| 1.466e-07 | -15.74 | TGGAAA_V$NFAT_Q4_01 | MSigDB lists | TGGAAA_V$NFAT_Q4_01 | 1781 | 241 | 17758 | 1761 |
CCNI,EMX1,LTBP1,ILDR1,PPP4R4,HSPG2,VANGL1,TSC22D3,CNOT8,SLC25A13,FHDC1,NDRG2,SYTL4,MORF4L2,HDAC6,PDGFB,TMC1,CMTM6,TSEN34,SH3KBP1,SLC9A7,NKAIN3,TYMP,ANKS6,LRRC6,CTGF,DPYSL2,RGS3,IL6ST,PAQR5,PHTF1,ELF5,MITF,STEAP2,AKR1B1,ATRNL1,MANF,TINAGL1,TMEM37,TECR,ARMCX6,BTBD3,TIAM1,SMARCA2,TRIM8,SERTAD4,TNS1,GALNT7,LDB2,ZFAND5,COL12A1,ABR,EDNRA,TMEM164,ENPP1,SLC25A4,KLF12,HOXA9,SERPINI1,KLF11,GLA,NRGN,MAFF,PCSK5,CDK17,ARAP3,MRC2,CHCHD7,UBASH3B,SOX9,ETV5,ISYNA1,CNTNAP2,GPSM2,RAB6A,FAM81A,DHRS3,ADAMTSL4,TNFRSF19,IL18R1,PSIP1,BMP2K,MECOM,TFAP4,CYR61,SLC16A6,ATP5H,FLRT3,TBCD,MDFIC,PIM1,GAD1,DGKG,C9orf72,IGSF3,CYP26B1,ELK3,TBC1D8B,MGAT4B,VWA1,PDK3,ANTXR1,NFIB,GNAS,XKRX,BCAR3,NCOA3,PRKAG2,ETS2,H1F0,SEMA4D,ITGA7,PELI2,NFKBIA,ITPR1,SLC4A3,SFMBT1,NR4A2,MDH1,DONSON,LTBP2,ATP1B3,ZNF502,SEMA3A,COL16A1,RARG,KLF7,DOCK9,SPRED1,NCKAP5,CEP70,HOXB7,CAST,CD82,DDIT4L,TP53,RNF182,FTH1,PRKACA,BCAP31,RAD23A,IER3,APLP2,SCNN1A,RNF220,FAM46A,WDR44,XYLT2,LMO4,BCL6,TWIST1,ESPN,PDE4D,SCN2A,RASGEF1A,SCN3A,DOCK4,CLCN3,CAPN6,LYRM1,SYNE2,ACO1,RAB38,ATP1B1,SNX12,FZD7,NIN,NFIX,IRS2,PDLIM3,NGFRAP1,PTK7,CORO1C,OVOL1,ADAMTS14,NRG1,KLF5,HS3ST3B1,SLC27A3,NR3C2,CTHRC1,SORT1,TM2D2,CPEB4,KLHL13,SDC4,MIER3,HMGN3,NOTUM,TRIB2,ETS1,HOXB2,PPP2R3A,WWP2,IL17RB,FOXP2,C16orf74,ADD3,ADORA1,ITGB8,RNF128,CALD1,RRBP1,TMBIM6,SGK1,ABCD1,ERBB3,IQGAP3,CITED2,SPRY2,ATP2B1,RBMS2,ADAMTS2,TGIF1,LCA5,RHOA,MOSPD2,NR3C1,NR4A1,BCL9,PPARA,GRIN1,C1GALT1C1,FOS,PITX2,HLA-B,SMTNL2,SCG2,PLOD2,HNRNPH2,RAP2C,NR4A3,FAM117A,SH3BGRL2,ZMIZ1,CEP41,PTGES,DEF6,JARID2,ESYT2,DIS3L |
| 1.509e-07 | -15.71 | intracellular organelle | cellular component | GO:0043229 | 11578 | 1253 | 17570 | 1756 |
HECA,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIPARP,MGAT5,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,COX6C,FAM21C,MARCH8,TFAP4,FRY,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,ZMYM1,MYLIP,NUP85,PPP6R1,MCCC2,REC8,PQLC3,PYM1,ERO1A,ELK1,PSMA4,GNA11,SFXN5,PLIN5,ETS2,S100A5,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,PTTG1,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,CKAP2,DCAF7,ESRP1,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,ACOT7,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,CPNE2,RPS6KA2,NPNT,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,STAU2,CBX6,NFE2L1,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,ADCK5,RAB6A,HES2,B4GALNT1,RINL,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,BCL6,PLK4,ZDHHC23,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,SCG2,SH3BGRL2,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,OAT,SLC9A7,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,PRDM5,BMP1,NFKBIZ,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,ZNRF2,BHLHE41,RPL39,VASN,DAPK1,TPST1,PRKG1,CACNA1D,SYTL3,GPR161,TRAK2,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,THRA,CCDC110,ATP2C2,FTH1,BCL2L1,CYP39A1,ZFYVE9,APOBEC3B,NOV,ACAP2,PDE4D,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,RAD17,PYGO1,PKMYT1,ITPR3,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,CENPI,PBX3,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,RAB15,HSF2,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,TPGS2,ELK3,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,ECE1,EPB41L4B,SEPHS1,CHP1,C3orf52,CD40,FANCE,CASP4,ARHGAP35,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,RAP2C,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,SYTL4,MORF4L2,BARD1,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,ICMT,CYP4F3,COL12A1,ANKRD6,DNM1L,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,CYB5A,DCP2,DHX32,STK17A,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,ARPC2,DRP2,NDE1,ZNF502,EGLN1,XDH,MTM1,CCDC109B,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SSH3,CAMSAP3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,SLC9A6,SIPA1L1,RGS14,TTC8,NKX3-1,RASSF7,PDIA3,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,ADD3,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,UNKL,MYL9,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,ELF5,DUSP10,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,ALDH3A2,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,CORO2A,SPATA13,TCF7,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,MFSD2A,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,N4BP3,LHX6,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,EVA1A,MBP,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,CCDC92,BUB1,ABCD1,KLF9,TLE6,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,FNDC3A,BCAR1,MAPK8IP1,PRDX4,FUCA1,SERPINA1,ZNF214,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,FAM101B,CENPN,NCS1,SESN3,CTGF,ZFP36,RGS3,STEAP2,PACSIN1,LAMP2,LOC81691,KIFC2,SNTB2,PBK,CASP9,TNS1,AGO4,PIF1,GALNT7,CCNF,SAV1,MCFD2,SLC25A5,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,FAM110C,DHTKD1,SARAF,TRAF5,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,KIAA1161,BMP2K,MECOM,SNX18,BDH1,SORL1,PIKFYVE,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,AMER1,PIP4K2C,VEZT,GLT8D2,STX3,FRMD4B,FAS,DGKH,PRKAG2,DCK,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,SNN,AIFM2,MNS1,APLP2,ZNF75D,CDKN1B,DAB2IP,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,HS3ST3B1,NR3C2,WASF3,NUDT6,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,NCOA2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,NUCB1,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,DNER,SH3KBP1,TSEN34,ABCD4,CHPF,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,MRPS36,PTGFRN,STK17B,CXXC4,NEIL1,ZNF114,RAP1GAP,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,RFX5,NCEH1,LRIF1,KDELR1,OXR1,GYLTL1B,HMG20B,GLCE,GNAS,FECH,ONECUT1,NUDT16,PLPP3,UTP14C,CDCA5,NFKBIA,ALPK3,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,ZNF525,OSTM1,ERBB2IP,DUSP4,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,ANXA3,SORT1,FRMD6,POC1B,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,MDM1,ADORA1,GALNS,KIAA0319,SYPL1,SUN2,RAB3B,NR4A1,ASPM,OGDHL,MBNL3,KLHL2,HLA-B,C2orf70,HNRNPH2,PRCP,DHRS2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 1.552e-07 | -15.68 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 189 | 43 | 17758 | 1761 |
PACSIN2,AVPI1,IGFBP6,CD63,TBC1D1,PSME2,TMEM41B,HLA-F,FBXO2,DSE,SPR,BCAP31,SIRPA,ARHGEF10L,GNS,APLP2,BHLHE41,GALNS,TMEM51,CD9,SGK1,PTPRE,SPRY2,SYK,GM2A,DVL2,CKAP4,CYP1B1,DOCK4,RIPK2,SAT1,CDA,TNS1,NPC2,SAV1,LHFPL2,ATP1A1,CORO1C,PLK2,ARSB,SLC27A3,NR3C2,IFI6 |
| 1.604e-07 | -15.65 | KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | MSigDB lists | KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | 76 | 24 | 17758 | 1761 |
INPP5D,CALM1,DGKQ,PIK3R1,PIP4K2C,CALM3,ITPR2,ITPR3,DGKE,CDS1,DGKH,CALM2,PLCG1,PTEN,PLCG2,ITPR1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,PLCB2,DGKG |
| 1.606e-07 | -15.64 | cellular component organization | biological process | GO:0016043 | 5336 | 638 | 16441 | 1675 |
ACACB,ADD1,MRPS15,AASS,AK7,HEXB,RET,CACNA2D2,NRG2,MORF4L2,SYTL4,CARD10,LTBP3,CALM2,WEE1,PSMD1,AP1M2,TUBG1,SEMA3G,TIAM1,DNAAF3,SPEF2,SMARCA2,CDA,MTRF1L,PRKAR2B,LOXL2,ICMT,ARF4,COL12A1,ABR,PLCG1,MID1IP1,DNM1L,LIMK1,TRAF3IP1,NOD2,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,SCN5A,ITGA6,SOX9,RAB23,GPSM2,MERTK,LMNA,ATG4A,ELF3,TFAP4,FRY,RIMS3,MEGF8,FLRT3,FAM13B,NEK2,ALPK1,PANX2,NCAM1,NUP85,PPP6R1,REC8,HPS3,KIF20A,PYM1,ERO1A,MYBL2,NPHP3,TP53INP2,PSMA4,PLIN5,PTPRF,NCOA3,TIMM8A,SEMA4D,SETD3,AURKA,CLMN,MDH1,NDE1,ARPC2,CFAP20,NUP58,MTM1,GRHL2,TMSB15A,ACTR8,PTTG1,C5orf30,TESK2,PKP2,NUF2,PRKACA,CCND1,CDH1,SP100,DACT1,ACSL4,DLG3,RASGEF1A,ETV4,SNX10,CAMSAP3,SSH3,SEC61B,COL6A2,FZD4,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,GTF2A2,SNX12,COX20,GABARAPL1,IRS2,PDLIM3,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,RGS14,MAPK12,TTC8,CTHRC1,SDC4,CTSZ,ANO9,PKN1,PLPPR4,ETS1,NEO1,DTX3L,ITGB8,IGSF9,CTSC,CST3,BAX,PLEKHF1,ADAM15,MAPK11,S100A6,CRTAP,ACBD5,PVRL4,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,RAPGEF2,GRIN1,UBE2A,CRISPLD2,CNTNAP1,RPL12,PLOD2,SYT7,NR4A3,ITGAV,HMGA1,CENPE,WDR45B,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDC80,LMCD1,F11R,HDAC6,PDGFB,SDC1,SPTB,RPS6KA2,NPNT,SHC3,CNTRL,MITF,NTN4,TLN2,ANO4,TRAM1,NEB,ZNF462,PLK1,KCNIP3,ING1,CELSR2,CBX6,EZR,ARFRP1,ANLN,CDK1,OPTN,DPYSL3,KDM4D,DZIP1L,MSL1,MAP2,WIPI1,PRKCDBP,MYL12B,PRKAA2,HJURP,LGALS3,RASA2,PDCL,NCKAP1,CNTNAP2,FBLN1,IGF1R,TBCD,EXOC8,WNT3A,CYP26B1,DPYSL5,MRPS33,TESK1,RGMB,CORO2A,SPATA13,STRADB,SCRIB,CDK5R1,H1F0,PVRL2,COL13A1,ITGA7,ZDHHC7,LTBP2,ATP1B3,TMEM120A,CCNB2,SEMA3A,IFI6,NF2,P3H2,TP53,ERBB2,STIL,EMP2,BCAP31,TMSB15B,SYTL2,TTC21B,PDGFA,ATP6V0B,SRR,BCL6,ZDHHC23,PLK4,CDH3,ESPN,LMAN1,SULF2,CTH,SIRT1,PPIF,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,MYL12A,DAG1,TAPBP,IDE,RBL1,PTK7,ADAMTS14,EFNA5,SYT13,BIN1,COL9A3,PINK1,PACSIN2,KLHL13,CDCA8,PSMD10,HMGN3,CRABP2,AIP,H1FX,NRP2,ZDHHC21,CDK16,SGK1,TRIM21,BUB1,ABCD1,HES1,FBLN5,RHOA,PSMB4,NR3C1,CRB3,AMFR,STMN3,COL7A1,BCAR1,BBS2,BORA,PRDX4,SERPINA1,FAT4,PGRMC1,PPP2R3C,SPCS3,TBC1D4,UBE2C,ARHGEF4,GOLGB1,SUN1,GAA,HSPG2,SSH1,ATP8A1,PSME1,PLXNA1,CCNB1,OAT,FAM101B,CENPN,TYMP,CTGF,ELMO2,PIK3CA,KCNS3,PACSIN1,XKR8,SPATA18,ACVR1C,PBK,CASP9,SLC35C1,KIF13A,TNS1,AGO4,PIF1,CCNF,MCFD2,ARHGEF26,PRIM1,SLC25A4,PLK2,GNPTAB,PRDM5,BMP1,UNC5B,F2RL1,FGD1,SEMA6B,MRPL44,TBC1D1,KIF23,SLC1A3,PSIP1,MECOM,DOPEY2,ITGA3,CYR61,SNX18,RPL39,PRKG1,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,EPB41L5,KCNJ12,DDB2,PMPCB,CALM1,ANO6,ATP8B3,EPHA1,JADE2,ANTXR1,NFIB,RASA1,STX3,FAS,DGKH,MMP15,PLEKHH2,PRKAG2,FAM64A,MATN2,FAM83D,FGD6,SFMBT1,KLK7,CABIN1,NR4A2,HOOK1,EHD1,SPRED1,SLC2A4,REPS2,TCTN2,DLGAP5,CEP70,TRIP10,ST14,RPS6KA1,IQGAP1,FTH1,KCTD12,BCL2L1,AIFM2,DDR1,MNS1,ZFYVE9,APLP2,DAB2IP,EPHB4,PDE4D,GPX4,ATG4D,SEMA3B,SEC23A,CAPN6,COG2,PRKCQ,SLC11A2,PKMYT1,PYGO1,ATP1B1,ITPR3,H2AFV,ALCAM,ATP10D,FZD7,NIN,CEP162,EPHA10,DDOST,JAK1,STK26,TRIOBP,NRG1,KLF5,MLKL,COBL,CBX7,WASF3,CENPI,ATP9A,EPS8,SPR,EFNB1,FGF19,SIX4,SLC25A36,SNTA1,PTEN,CD9,ATP8B1,ERBB3,SPRY2,NCOA2,FARP2,PDGFC,RASGRF1,B3GNT2,SHMT1,ARHGEF28,ZWINT,FURIN,DIAPH2,C1GALT1C1,YES1,KIF11,DCTN6,FGFR2,RYK,GRIN2D,GPER1,WDR62,NCAPG2,ARSB,ESPL1,OCLN,JARID2,RGMA,EMX1,CASP3,LTBP1,UGT8,MPP5,CACNB4,DNER,SH3KBP1,ZFYVE16,RAB15,LRRC6,DPYSL2,CEP78,DLG1,TRPC1,SUN3,RAB20,RP2,MYH14,CTTN,BTBD3,RASGRP1,CYP1B1,ATL1,CENPA,STRIP2,ARHGDIB,MRPS36,PTGFRN,TYSND1,CAPN1,NR2C2,PIFO,ARAP3,SERPINE2,BVES,PEX6,ETV5,CALM3,ADAMTSL4,KCNN4,COL6A1,FXYD5,LIMCH1,ZRANB1,SLC12A2,ALS2CL,CCDC88A,SNX7,VWA1,HMG20B,NUBP1,RANBP9,FECH,ONECUT1,TMEM30A,CDCA5,PITPNA,SHROOM2,JAK3,RARG,COL16A1,SNX30,KLF7,GAS2L1,DYNLRB1,LZTFL1,SORBS1,SPC25,PSME2,HDAC11,COL18A1,TDRKH,MRAS,KCTD9,SS18,SETDB2,ARTN,FRYL,KIF14,ZDHHC12,REEP1,RPN2,EPB41L4B,F2R,FRS3,CHP1,CKS2,GCA,ERBB2IP,CD40,KCTD2,ARHGAP35,JADE1,ALDH5A1,PEX2,SPTBN5,REEP4,LIFR,PPP2R2D,ABCA1,GCLM,FBLIM1,SORT1,ARHGEF11,TSPAN15,FRMD6,POC1B,CIT,LRP4,COL4A5,TGFBR1,HMGXB4,HDAC9,SAC3D1,TOP2A,KIF5B,TAF1B,ADORA1,LLGL2,A4GALT,BMP7,TOX2,IQGAP3,MYO5A,SUN2,RAB3B,CFAP46,GCLC,ASPM,CTSL,SWAP70,RND3,CTSV,RAP2C,SPINT2,ARRB1,GEM,PLOD3,CEP41,ZMIZ1,L1CAM,ABCG1 |
| 1.611e-07 | -15.64 | cytoskeleton organization | biological process | GO:0007010 | 860 | 135 | 16441 | 1675 |
SUN1,UGT8,SSH1,ADD1,AK7,NDC80,F11R,FAM101B,SH3KBP1,WEE1,LRRC6,ELMO2,DPYSL2,DLG1,TUBG1,SUN3,RP2,MYH14,CTTN,TLN2,PACSIN1,DNAAF3,PLK1,SPEF2,CENPA,STRIP2,EZR,ARHGDIB,ANLN,CDK1,ABR,DPYSL3,MAP2,PLK2,LIMK1,PRKCDBP,TMOD2,ITPKA,ARF6,FGD1,ARAP3,SOX9,KIF23,NCKAP1,GPSM2,LMNA,FRY,TBCD,NEK2,PRKG1,LIMCH1,ZRANB1,MAST4,EPB41L5,KIF20A,CORO2A,MYBL2,STRADB,ANTXR1,RANBP9,PVRL2,FGD6,AURKA,NDE1,ARPC2,SHROOM2,GAS2L1,MTM1,SORBS1,NF2,SPC25,TRIP10,TMSB15A,TESK2,PKP2,MRAS,EMP2,STIL,TMSB15B,PDGFA,SS18,FRYL,KIF14,PLK4,BCL6,ESPN,EPB41L4B,CHP1,CAMSAP3,CAPN6,FIGNL1,SYNE2,NUSAP1,ERBB2IP,DAG1,NIN,PDLIM3,SHROOM3,PTK7,CORO1C,SIPA1L1,TRIOBP,SPTBN5,RGS14,COBL,WASF3,PACSIN2,ARHGEF11,EPS8,SIX4,PTEN,LLGL2,SPRY2,FARP2,SUN2,RHOA,ARHGEF28,TACC1,FMN1,CFAP46,ASPM,STMN3,DIAPH2,KIF11,BBS2,BCAR1,DCTN6,CNTNAP1,SWAP70,RND3,ARRB1,PPP2R3C,CENPE,WDR62,ESPL1 |
| 1.636e-07 | -15.63 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | 139 | 35 | 17758 | 1761 |
LASP1,PCOLCE,TM2D2,PAPSS2,ASAH1,COL4A5,FAM101B,DHRS3,DDR1,EMP2,WWP2,CTGF,LLGL2,IL6ST,CD9,CITED2,SNX10,S100A13,CTDSP2,CRTAP,RBMS2,AMOTL2,SEC61B,PRSS23,SESN1,FOS,TP53INP2,C3orf58,SOCS3,TIMP3,SHROOM3,SLC4A3,FHL1,TMEM159,TOB1 |
| 1.679e-07 | -15.60 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | 196 | 44 | 17758 | 1761 |
LZTFL1,EPAS1,NDC80,ASAH1,TEX2,NUF2,MNS1,CENPN,CARD10,KCTD9,IL17RB,TTC21B,RCN1,FAM111A,FAM46A,METTL7A,SLC16A6,FRYL,MGAT4A,OSBPL3,PLEKHF1,ALDH7A1,BUB1,IFIT1,SYTL3,RASGRP1,CYP1B1,FIGNL1,CORO2A,LITAF,NUSAP1,ANLN,CDK1,XKRX,AHRR,HLF,DNM1L,ANKRD6,TRAF3IP1,MATN2,NR4A3,ABCB1,NCAPG2,SERPINB1 |
| 1.679e-07 | -15.60 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | 196 | 44 | 17758 | 1761 |
LAMP1,GAA,LGALS3,S100A11,HEBP1,ZCCHC24,BLVRB,HEXB,EFHD2,KCTD12,ARHGEF40,TSEN34,SIRPA,ARHGEF10L,GNS,APLP2,CST3,DAPK1,PTPRE,SLC16A5,S100A6,CYP1B1,CPD,ALDH2,S100A4,MPP1,PLAUR,SAT1,BLVRA,ASB13,CRISPLD2,TMEM164,ALDH3B1,SERPINA1,HPSE,ETS2,SECTM1,NOD2,ZDHHC7,CTSA,PLIN3,ZMIZ1,SLC27A3,RRAGD |
| 1.714e-07 | -15.58 | endosome | cellular component | GO:0005768 | 780 | 123 | 17570 | 1756 |
LAMP1,EXPH5,MTM1,SLC2A4,NF2,IL15,EPHA4,RET,ERBB2,TGOLN2,SYTL4,MVB12B,DNER,ZFYVE9,SLC9A7,ZFYVE16,RAB15,ATP6V0B,ACAP2,CDH1,WDR44,STEAP2,ABCA2,TUBG1,CDKN1B,SNX16,RAB20,ECE1,MARCH2,LGMN,RAB27B,F2R,SNX10,TMEM9,MYO5B,LAMP2,CLCN3,PANK1,EZR,SLC11A2,KIF13A,RAB38,SNX12,OPTN,ATP1A1,WIPI1,KCNK1,SLC9A6,ATP7B,RAB11FIP1,IRF7,ARF6,F2RL1,RRAGD,STARD3NL,SORT1,PACSIN2,GOLIM4,SCOC,CD63,GGA1,TMEM55B,ATP9A,HLA-E,HLA-F,RAB23,TGFBR1,CNTNAP2,PKN1,FAM21C,PARM1,VPS26A,HLA-A,M6PR,MARCH8,RNF128,SNX18,ZNRF2,CST3,KIAA0319,EXOC8,SGK3,PLEKHF1,SORL1,HLA-C,PIKFYVE,WNT3A,C9orf72,TPCN1,GPR161,MYO5A,SNX7,TRAK2,AMOTL2,SUN2,RAB3B,RHOA,MMD,IFITM3,RAPGEF2,DIAPH2,NEURL1B,ANTXR1,CPTP,STEAP1,DGKH,CTSL,HLA-B,NUCB1,AP1AR,RAB11FIP2,RAP2C,GPER1,PLD1,ARPC2,FZD5,PLIN3,NDFIP1,NIPA1,SNX30,RUSC1,ABCG1,EHD1 |
| 1.721e-07 | -15.58 | positive regulation of kinase activity | biological process | GO:0033674 | 619 | 104 | 16441 | 1675 |
SPRED1,TXN,AVPI1,PSME2,CAMKK1,IQGAP1,EPHA4,NRG2,ERBB2,PSME1,PRKACA,PDGFB,STIL,ERP29,EMP2,CARD10,SPTB,GRM5,CALM2,CCND1,PDGFA,PSMD1,SHC3,KIF14,PIK3CA,DLG1,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,MAP3K3,SIRT1,RIPK2,AKT1,FZD4,PRKAR2B,CD40,CDK1,MAP3K6,IRS2,PLCG1,GPRC5B,JAK1,STK26,MADD,NOD2,CAB39,SLC27A1,EFNA5,SPTBN5,NRG1,GAB1,PIFO,PINK1,NKX3-1,RASA2,SDC4,CALM3,PSMD10,TGFBR1,PKN1,FGF19,ADORA1,CYR61,BAX,MAP3K9,MAPK11,MDFIC,PIM1,ERBB3,NCAM1,WNT3A,IQGAP3,SYK,SPRY2,CCDC88A,MDFI,PDGFC,RASGRF1,MMD,PSMB4,RAPGEF2,CALM1,GRIN1,RGCC,STRADB,PDE5A,PSMA4,CDK5R1,RASA1,MAPKAPK2,PRKAG2,FGFR2,CSF1,ARRB1,PPP2R3C,GRIN2D,STK39,CENPE,FZD5,MAP3K5,JAK3 |
| 1.729e-07 | -15.57 | morphogenesis of an epithelium | biological process | GO:0002009 | 425 | 78 | 16441 | 1675 |
GRHL2,LGR4,ST14,EPHA4,RET,MPP5,PLXNA1,PRKACA,DDR1,STIL,SETDB2,NPNT,LMO4,ALDH1A3,DLG1,TWIST1,TACSTD2,DLG3,ETV4,DVL2,EZR,TFAP2C,DAG1,EDNRA,SOCS3,ARHGAP35,SHROOM3,PTK7,COBL,CTHRC1,NKX3-1,SDC4,SOX9,RAB23,CTSZ,NCKAP1,HOXB2,SIX4,FZD6,CTNNBIP1,CA2,IGF1R,CYR61,FLRT3,MEGF8,FRAS1,BMP7,BAX,TFAP2A,WNT3A,SLC12A2,SPRY2,EPB41L5,HES1,TGIF1,RHOA,SALL4,FMN1,PRICKLE1,SCRIB,NPHP3,ARHGAP24,NCOA3,FAT4,FGFR2,ACVRL1,CSF1,TBX18,CTSV,SPINT2,HOXB13,SOX8,OSR1,FZD5,PLOD3,SEMA3A,RARG,ADAMTS16 |
| 1.782e-07 | -15.54 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 797 | 124 | 17775 | 1757 |
NF2,CAMKK1,RPS6KA1,EPHA4,RET,PPFIBP2,TP53,ERBB2,TESK2,GRK6,CAMK1D,CCNB1,PRKACA,DDR1,TMC1,TMPRSS4,CYP26A1,DAPK2,WEE1,RPS6KA2,ZNF687,WDR44,PIK3CA,PLK4,EPHB4,PHKA2,ZNF365,SCYL3,PLK1,SUSD3,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,RNF19B,MAP3K6,ATP10D,ADRBK2,STK17B,TRIM9,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,INPP4B,DHTKD1,HDAC1,SERPINI1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,LRRFIP2,SDC4,C6orf106,TGFBR1,COL4A5,ADCK5,NCKAP1,PKN1,TRIB2,MERTK,BMP2K,PPP2R3A,KIF5B,E2F7,IGF1R,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,OSTF1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,MPHOSPH9,RIMS2,PHF20L1,ADCK3,TESK1,PIK3R1,STRADB,RUNX3,EIF2AK1,YES1,PDK3,PDIK1L,STK17A,GPLD1,MAPKAPK2,ACVRL1,FGFR2,PRPS2,ALPK3,ARRB1,AURKA,GRIN2D,CDK18,MAP3K5,DRP2,NDE1,JAK3,HIPK3,NRBP1,MELK,DIS3L |
| 1.782e-07 | -15.54 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 797 | 124 | 17775 | 1757 |
NF2,CAMKK1,RPS6KA1,EPHA4,RET,PPFIBP2,TP53,ERBB2,TESK2,GRK6,CAMK1D,CCNB1,PRKACA,DDR1,TMC1,TMPRSS4,CYP26A1,DAPK2,WEE1,RPS6KA2,ZNF687,WDR44,PIK3CA,PLK4,EPHB4,PHKA2,ZNF365,SCYL3,PLK1,SUSD3,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,RNF19B,MAP3K6,ATP10D,ADRBK2,STK17B,TRIM9,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,INPP4B,DHTKD1,HDAC1,SERPINI1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,LRRFIP2,SDC4,C6orf106,TGFBR1,COL4A5,ADCK5,NCKAP1,PKN1,TRIB2,MERTK,BMP2K,PPP2R3A,KIF5B,E2F7,IGF1R,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,OSTF1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,MPHOSPH9,RIMS2,PHF20L1,ADCK3,TESK1,PIK3R1,STRADB,RUNX3,EIF2AK1,YES1,PDK3,PDIK1L,STK17A,GPLD1,MAPKAPK2,ACVRL1,FGFR2,PRPS2,ALPK3,ARRB1,AURKA,GRIN2D,CDK18,MAP3K5,DRP2,NDE1,JAK3,HIPK3,NRBP1,MELK,DIS3L |
| 1.786e-07 | -15.54 | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 177 | 41 | 17758 | 1761 |
DLGAP5,FOXM1,CENPI,PTTG1,PDIA5,DNAJB11,NUF2,CCNB1,SDC1,PARM1,ATG4A,KIF14,BHLHE41,PHTF1,SLC44A1,UBE2J1,TUBG1,RPN2,BUB1,MANF,LMAN1,HMMR,SEC61B,ERLEC1,ZWINT,PBK,CDC20,GGH,NUSAP1,KIF11,CDK1,MUM1L1,GPLD1,PRDX4,WFS1,AURKA,CCNB2,GLCCI1,E2F8,MELK,DENND5B |
| 1.816e-07 | -15.52 | GSE1460_DP_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_DN | 190 | 43 | 17758 | 1761 |
SCN5A,EPAS1,HLA-E,SOX9,PPFIBP2,PDIA5,SELL,ASAH1,BTN3A1,NDRG2,B4GALT4,DENND2D,BMP2K,PDIA4,SGPL1,SCML1,PDGFA,SP100,IL6ST,AIM1,PCYOX1,FAM102A,PIK3CD,HLA-C,PDE4D,ZNF365,SLC16A5,SCN3A,CD55,ELK3,ABR,STK17A,EDNRA,RASGRP2,FUCA1,HLA-B,SCARB2,RPL12,NR4A3,ARRB1,TBC1D4,AHR,EHD1 |
| 1.863e-07 | -15.50 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9663 | 1056 | 17775 | 1757 |
HECA,AK7,HEXB,RET,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,TMEM37,RNF26,TIAM1,DNAAF3,FBXL16,CDA,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,ATG4A,MARCH8,TFAP4,MEGF8,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,HPS3,ELK1,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,ADAMTS16,DOCK9,TPRN,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,RASGEF1A,DLG3,ZNF365,ETV4,SNX10,MYT1,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,ZNF618,SNX12,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,MAPK12,CKAP2,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,BAX,ACBD5,ADAMTS2,TACC1,PIK3R1,NUB1,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,SYT7,PPM1H,ITGAV,ACOT7,BCAM,KIAA1462,EPAS1,ARFGEF1,DNAJB11,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,RPS6KA2,IL6ST,SLC44A1,ABCA2,NTN4,SCARA3,PLK1,THRB,CELSR2,CBX6,CR2,ARFRP1,SESN1,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,HOXA9,KLF11,RRAGD,PARP12,RUNX2,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,FRAS1,PIM1,MPHOSPH9,CKAP4,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,CCNB2,USP43,TP53,STIL,BCAP31,WDR44,LMO4,BCL6,PLK4,NOTCH3,OAS3,LMAN1,SULF2,PPIF,AKT1,PTGER4,ACO1,TAPBP,PTPRJ,RBL1,STK38,MMP17,EFNA5,ZMAT1,BIN1,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,GDF15,HMGN3,AIP,LBR,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,UBE2J1,TFAP2A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,WBP5,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,BBS2,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LGR4,HSPG2,VANGL1,TSC22D3,CAMK1D,SLC9A7,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,PIK3CA,SNX16,ARMCX6,SPATA18,ACVR1C,ANKRD10,LRIG1,SERPINI1,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,RALGPS2,LYPD3,BHLHE41,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,ADCK2,CACNA1D,GPR161,TRAK2,SOCS5,PRODH,KCNJ12,KLK5,ADCK3,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,MATN2,AGBL5,CABIN1,CDK18,KLK7,PER3,IFIH1,MFSD3,SPRED1,REPS2,ST14,THRA,ATP2C2,BCL2L1,DDR1,ZFYVE9,EPS8L2,APOBEC3B,NOV,TRANK1,EPHB4,PDE4D,DOCK4,FOXJ2,CYB5R2,UTRN,PKMYT1,PYGO1,ATP1B1,ITPR3,ASB13,FZD7,DDOST,NGFRAP1,COBL,CBX7,IER5L,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,SCML1,WWP2,E2F7,TMEM87B,GNB5,RNF128,DRAM1,ERBB3,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,FGFR2,TBX18,ABCB1,FZD5,ESPL1,CXorf56,MELK,DEF6,RGMA,MPP5,TRIM68,HTR1D,RAB15,SIPA1L2,ANKFN1,CTTN,SP5,NLRP4,CENPA,USP18,ITCH,RGAG1,ARHGDIB,GPRC5B,HPSE,MADD,ZNF165,CAB39,SP6,GLA,PCSK5,NR2C2,CD99,LASP1,ARAP3,PPP1R2,SERPINE2,ETV5,ASB9,ABCG2,ADAMTSL4,COL6A1,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,ELK3,HEATR5A,NUBP1,PDIK1L,STEAP1,MFSD7,RANBP9,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,RARG,AFAP1,APOL2,LMO7,CCNE2,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,DIXDC1,ECE1,CKS2,PTPRU,GLO1,CD40,FANCE,CASP4,SOCS3,ARHGAP35,SPTBN5,LNP1,GLIS3,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,TMEM63A,HDAC9,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,BMP7,TOX2,CLIP2,MYO5A,PGM1,SYBU,TTC7A,RUNX3,TCEAL8,FOXL1,ARHGAP24,ENDOD1,SWAP70,RND3,RAP2C,ZMIZ1,AHR,RAB3IL1,ABCG1,ACACB,KLK10,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,FAM102B,NRG2,DHX8,SYTL4,MORF4L2,BARD1,EPDR1,DAPK2,WEE1,KIAA1107,CYP2S1,KLF3,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,SEMA3G,APOBEC3G,SMARCA2,NWD1,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,PGF,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,GAB1,HOXC13,FAM169A,ALDH6A1,MERTK,LMNA,ELF3,FAM189A1,NEK2,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,DHX32,STK17A,PTPRF,NCOA3,SEMA4D,TIMM8A,ITPR1,AURKA,MDH1,NDE1,DRP2,FBXO27,ZNF502,SERPINB1,EGLN1,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,FZD4,CYS1,SYNE2,PLEKHO1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,ANO9,PKN1,ARHGEF40,ETS1,SRPX2,NEO1,CXCL16,ADD3,SLC27A6,ANKS1B,ALG13,CALD1,TMBIM6,ADAM15,PLEKHF1,NKAPP1,MAPK11,WWP1,CRTAP,AMOTL2,FMN1,BCL9,RAPGEF2,MYEOV,SNTB1,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,TRIM2,FAM199X,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,PDGFB,NUP62CL,CNTRL,SHC3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,NEB,CCDC38,ZNF462,PCGF5,CD55,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,LHFPL2,RHEB,OPTN,MAP2,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,BMF,ASAH1,CNTNAP2,DHRS3,IL18R1,IGF1R,GATA2,SPIN4,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,EPN3,COQ10A,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,NIPA1,RNF146,UPF3B,NF2,FOXM1,ERBB2,CCDC68,SLC7A2,CYP26A1,RAD23A,ATP6V0B,PLCG2,SCN2A,EGLN3,MINPP1,DVL2,GM2A,SIRT1,CPD,TMTC1,MBP,CDC20,MYL12A,DNAJC10,PRRT4,PTK7,ADAMTS14,AIFM3,ZNF701,CMTM4,MAN2B2,GOLIM4,MACC1,RUSC2,PSMD10,GABRG2,NKRF,SIRPA,PPP2R3A,ABCD1,BUB1,FAIM,IGDCC4,DLGAP1,HMMR,LITAF,BCAR1,MAPK8IP1,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,ZNF214,TMC5,CDCA7L,PGRMC1,NETO2,PPP2R3C,UBE2C,TBC1D4,DIS3L,GAA,PPP4R4,PPFIBP2,TAP1,PLXNA1,CCNB1,SLC20A1,CTGF,PRICKLE3,IQCE,RGS3,ZFP36,IL31RA,ATRNL1,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,HSPA12A,CASP9,NBPF3,TNS1,PIF1,CCNF,SAV1,SLC25A5,TP53I3,SPNS3,AHRR,HLF,RBM47,PTER,PLK2,NKD1,FAM110C,DHTKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,C6orf106,KIF23,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,DDB2,PMPCB,MFI2,TBC1D8B,AMER1,PIP4K2C,RASA1,FRMD4B,FAS,DGKH,PRKAG2,TMEM54,ISM1,TCEAL4,SLC4A3,PCDH19,MAP3K5,NRBP1,PLA2G4A,FRMPD3,CEP70,ARMCX3,TRIP10,RPS6KA1,CD274,AIFM2,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,PHKA2,LGMN,MYO5B,SEC23A,CAPN6,PRKCQ,ZNF469,NIN,PRDM11,CMTM7,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,ARHGEF3,ARL4C,APOBEC3H,CYB561,SIX4,TMCC3,SNTA1,PTEN,SGK3,ATP8B1,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,SHMT1,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,MAMDC4,AMMECR1,CSTF2,ETAA1,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,CASP3,LTBP1,CAMKK1,DNER,DENND2D,TMC1,KREMEN1,SH3KBP1,PTCHD4,ABCD4,CHPF,NKAIN3,ARHGEF10L,C7orf49,ZCCHC12,TSPAN6,DLG1,ANKRD12,POF1B,RAB20,RP2,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,ADRBK2,STK17B,CXXC4,MDK,ARHGEF19,NEIL1,UEVLD,RAP1GAP,GRN,FAM213B,LRRFIP2,PHLPP1,OTUD1,AIM1L,CA2,KCNN4,FXYD5,LRIF1,ALS2CL,OXR1,GYLTL1B,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,GNAS,ONECUT1,SLC6A6,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,PROM2,SPC25,MORC4,ARHGEF16,SS18,FRYL,TWIST1,RPN2,F2R,PDIA6,SCYL3,FRS3,MAP3K3,SUSD3,ZNF525,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,CYP2U1,REEP4,LIFR,PPP2R2D,LRP4,TRMT2B,POMGNT1,IL17RB,MDM1,MLPH,GALNS,IQGAP3,RAB3B,ASPM,NR4A1,LRRC66,MBNL3,OGDHL,KLHL2,HLA-B,DHRS2,HNRNPH2,HOXB13,SOX8,GEM,L1CAM |
| 1.867e-07 | -15.49 | RIGGI_EWING_SARCOMA_PROGENITOR_UP | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 407 | 74 | 17758 | 1761 |
ACACB,NCKAP5,KIAA1462,EPHA4,LMCD1,IL13RA1,CD274,CDS1,PDGFA,ZCCHC12,PAQR5,LMO4,PLCG2,REEP1,STEAP2,TMEM37,F2R,PCGF5,FZD4,SLC39A8,PTGER4,ARHGDIB,LDB2,EDNRA,PGF,HS6ST1,ENPP1,ATP1A1,ALDH5A1,JAK1,ZNF704,NR3C2,RRAGD,FBLIM1,KLHL13,POC1B,HLA-E,EFHD2,GDF15,ISYNA1,TRIB2,PARM1,ZDHHC21,HDAC9,GATA2,FLRT3,BHLHE41,TOX2,DAPK1,OPN3,CADPS2,IGFBP2,TSPAN13,ALDH7A1,CITED2,IGDCC4,IGSF3,CYP26B1,HES1,STAT4,PIK3R1,SPATA13,STMN3,FOS,STEAP1,GLCE,GALNT3,CACHD1,FAT4,PGM2L1,MAP3K5,JAK3,TMEM173,JARID2 |
| 1.903e-07 | -15.47 | AKT_UP_MTOR_DN.V1_UP | MSigDB lists | AKT_UP_MTOR_DN.V1_UP | 171 | 40 | 17758 | 1761 |
MAN2B2,TPRN,GGA1,CAMKK1,C6orf106,FBXO6,TMPRSS4,KCTD9,PARM1,SGPL1,TMCC3,CXCL16,IGF1R,A4GALT,SLC44A1,DUSP10,VAT1,TNFRSF12A,TACSTD2,IFIT1,LGMN,MYO5B,TGIF1,CD55,PLSCR1,GUSB,SLC39A8,C3orf52,AK4,PDK3,RNF19B,NIN,SLC6A6,PTPRJ,TJP3,GDE1,PLK2,CLMN,SH3BGRL2,MAL2 |
| 1.957e-07 | -15.45 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 378 | 70 | 18293 | 1814 |
CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,CAMK1D,GRK6,PRKACA,DAPK2,WEE1,RPS6KA2,PASK,PLK4,EPHB4,PLK1,AKT1,ACVR1C,PRKCQ,PKMYT1,MAP3K6,ADRBK2,STK17B,CDK1,JAK1,STK26,CDK19,PLK2,STK38,AXL,LIMK1,MAPK12,PRKAA2,LMTK3,CDK17,NUAK1,CIT,TGFBR1,TEC,PKN1,MERTK,ADRBK1,IGF1R,CDK16,MAP3K9,PRKG1,DAPK1,SGK3,SGK1,MAPK11,BUB1,PIM1,SYK,TESK1,EIF2AK1,EPHA1,YES1,PDIK1L,STK17A,MAPKAPK2,ACVRL1,FGFR2,CSNK1G1,AURKA,STK39,CDK18,MAP3K5,JAK3,HIPK3,MELK |
| 1.958e-07 | -15.45 | P53_DN.V1_UP | MSigDB lists | P53_DN.V1_UP | 184 | 42 | 17758 | 1761 |
EXPH5,SUN1,LTBP1,KLK10,UGT8,IGFBP6,SOX9,SDC4,NDC80,IL18,GPSM2,DHRS3,HDAC9,CTNNBIP1,EPCAM,SCNN1A,CYR61,AIM1,CD9,TACSTD2,RP2,CDKN2D,SPRY2,SMAGP,LAMP3,ENPP4,CORO2A,YES1,LHFPL2,BCAR3,LRRC42,SCG2,COL13A1,AXL,PTK7,LRIG1,SPINT2,ZNF165,KLF5,MAP3K5,AHR,MAFF |
| 2.030e-07 | -15.41 | extracellular matrix organization | biological process | GO:0030198 | 369 | 70 | 16441 | 1675 |
LTBP1,CASP3,HSPG2,P3H2,COL18A1,F11R,DDR1,PDGFB,SDC1,LTBP3,PDGFA,APLP2,CDH1,CTGF,NPNT,NTN4,CYP1B1,SULF2,TIMP2,COL6A2,LOXL2,DAG1,COL12A1,BMP1,ADAMTS14,CAPN1,COL9A3,LGALS3,ITGA6,LRP4,SDC4,SOX9,COL4A5,TGFBR1,ADAMTSL4,FBLN1,ELF3,ITGA3,ITGB8,CYR61,BMP7,COL6A1,CST3,EXOC8,ADAM15,WNT3A,NCAM1,CRTAP,ADAMTS2,FBLN5,ERO1A,FURIN,VWA1,COL7A1,NPHP3,CRISPLD2,PRDX4,MMP15,CTSL,COL13A1,PLOD2,ITGA7,SPINT2,CTSV,KLK7,LTBP2,ITGAV,PLOD3,COL16A1,TLL2 |
| 2.082e-07 | -15.38 | BERENJENO_TRANSFORMED_BY_RHOA_UP | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_UP | 521 | 89 | 17758 | 1761 |
PLA2G4A,CASP3,SORBS1,TXN,DLGAP5,FOXM1,PTTG1,TP53,GRK6,CCNB1,FAM101B,PHLDA1,IER3,CCND1,SS18,CTGF,UBE2T,NPNT,PLK4,TUBG1,PTPRE,CKS2,CLCN3,CENPA,FIGNL1,CDC20,PTGER4,EZR,SLC11A2,NUSAP1,CCNF,ANLN,ALCAM,CDK1,DPYSL3,PRIM1,RBL1,PLK2,CORO1C,NFKBIZ,E2F8,ANXA3,GCLM,IGFBP6,CKAP2,ITGA6,ARL4C,CDCA8,KIF23,PBX3,LBR,TOP2A,CYR61,RANBP1,BAX,NEK2,BUB1,AHCY,TAGLN2,IQGAP3,NUP85,TGIF1,SHMT1,PLSCR1,PQLC3,KIF20A,NR4A1,ASPM,PLAUR,MYBL2,KIF11,NUBP1,C3orf58,FAM64A,SLC4A4,TIMM8A,NR1D2,PVRL2,DCK,CDCA5,NFKBIA,CDCA7L,CSTF2,AURKA,FHL1,ATP1B3,NDE1,PKIA,ACOT7 |
| 2.113e-07 | -15.37 | SCIBETTA_KDM5B_TARGETS_DN | MSigDB lists | SCIBETTA_KDM5B_TARGETS_DN | 77 | 24 | 17758 | 1761 |
HMMR,GCA,SMARCA2,DLGAP5,PBK,SOX9,NDC80,CCNB1,CDK1,PSIP1,LGALS3BP,CYB5A,PLS3,TOP2A,SS18,SWAP70,SCNN1A,FJX1,REEP1,AURKA,LIMCH1,IGFBP2,FHL1,TMEM14A |
| 2.123e-07 | -15.37 | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | 191 | 43 | 17758 | 1761 |
LAMP1,CCDC109B,TXN,PARP12,IL15RA,CD63,GNPDA1,PSME2,TAP1,DHX8,CALM3,HERC5,HERC6,LGALS3BP,HLA-A,CALM2,SP100,TRANK1,SLC16A6,IFIT1,KLF9,PIM1,GM2A,KDELR1,MX1,PLSCR1,SLC39A8,MICB,DRAP1,USP18,CALM1,TNS1,SNTB1,IFIT3,SPTLC2,NUCB1,SEMA4D,NMI,IRF7,CTSA,PLIN3,IFIH1,IFI6 |
| 2.175e-07 | -15.34 | GNF2_TTK | MSigDB lists | GNF2_TTK | 38 | 16 | 17758 | 1761 |
HMMR,ZWINT,HJURP,FOXM1,ASPM,CDC20,NDC80,NUSAP1,KIF11,CDK1,FANCI,TOP2A,PLK4,CCNB2,MELK,CKS2 |
| 2.180e-07 | -15.34 | GABRIELY_MIR21_TARGETS | MSigDB lists | GABRIELY_MIR21_TARGETS | 279 | 56 | 17758 | 1761 |
RMND5A,TRIM2,ARMCX3,GNE,EPHA4,ARFGEF1,FAM102B,MPP5,PM20D2,FANCI,TOP2A,B3GALNT1,ACAP2,RALGPS2,ITGB8,FAM46A,CNTRL,CALD1,MGAT4A,OSBPL3,AIM1,DLG1,EXOC8,LIMCH1,RP2,ZRANB1,BTBD3,RASGRP1,PARP9,ACBD5,PHF20L1,TACC1,LPGAT1,SYNE2,PIK3R1,PPARA,UTRN,SESN1,NFIB,TIMP3,RAB11FIP2,ZNF367,HOXA9,SLC9A6,CLIP4,KLF5,EIF4EBP2,YOD1,PLD1,PER3,OSR1,GLCCI1,LIFR,SNX30,CYBRD1,ESYT2 |
| 2.223e-07 | -15.32 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 784 | 122 | 17775 | 1757 |
NF2,FAM92A1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,BCL2L1,CAMK1D,PRKACA,DDR1,SPTB,CDKN2C,TTC21B,CCND1,DAPK2,WEE1,RPS6KA2,CDH1,MITF,BCL6,PIK3CA,PLK4,EPHB4,CTTN,SCYL3,PLK1,MAP3K3,CELSR2,RIPK2,AKT1,ACVR1C,PBK,SYNE2,KIF1C,PRKCQ,ARFRP1,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,EPHA10,IRS2,PLCG1,RBM47,JAK1,CDK19,PLK2,PTK7,STK38,AXL,GNPTAB,LIMK1,NFKBIZ,MLKL,MAPK12,PCSK5,PRKAA2,PINK1,CDK17,ARHGEF11,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,HDAC9,IGF1R,ADRBK1,CDK16,PTEN,MYCL,NEK2,DAPK1,SGK3,PRKG1,MAP3K9,ADCK2,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,ATP2B1,NFE2L3,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,SNTB1,PDIK1L,GNA11,STK17A,GNAS,MAPKAPK2,CACHD1,ACVRL1,FGFR2,UTP14C,PHLPP2,ALPK3,AURKA,CDK18,PLD1,ITGAV,MAP3K5,JAK3,HIPK3,NRBP1,RUSC1,MELK |
| 2.223e-07 | -15.32 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 784 | 122 | 17775 | 1757 |
NF2,FAM92A1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,BCL2L1,CAMK1D,PRKACA,DDR1,SPTB,CDKN2C,TTC21B,CCND1,DAPK2,WEE1,RPS6KA2,CDH1,MITF,BCL6,PIK3CA,PLK4,EPHB4,CTTN,SCYL3,PLK1,MAP3K3,CELSR2,RIPK2,AKT1,ACVR1C,PBK,SYNE2,KIF1C,PRKCQ,ARFRP1,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,EPHA10,IRS2,PLCG1,RBM47,JAK1,CDK19,PLK2,PTK7,STK38,AXL,GNPTAB,LIMK1,NFKBIZ,MLKL,MAPK12,PCSK5,PRKAA2,PINK1,CDK17,ARHGEF11,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,HDAC9,IGF1R,ADRBK1,CDK16,PTEN,MYCL,NEK2,DAPK1,SGK3,PRKG1,MAP3K9,ADCK2,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,ATP2B1,NFE2L3,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,SNTB1,PDIK1L,GNA11,STK17A,GNAS,MAPKAPK2,CACHD1,ACVRL1,FGFR2,UTP14C,PHLPP2,ALPK3,AURKA,CDK18,PLD1,ITGAV,MAP3K5,JAK3,HIPK3,NRBP1,RUSC1,MELK |
| 2.259e-07 | -15.30 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 238 | 50 | 17758 | 1761 |
CCNI,CASP3,TXN,TRIP10,SDC4,IL13RA1,PLXNA1,C3orf18,SGPL1,LYPD3,DPYSL2,ZFP36,IL6ST,SORL1,EGLN3,SLC16A5,FAM69A,SEPHS1,LAMP3,GFPT1,FOXJ2,LITAF,RUNX3,RAB38,ZFAND5,MAP3K6,ADRBK2,STK17B,CYB5A,CD83,RASGRP2,OPTN,NCOA3,DUOX1,JAK1,PVRL2,SPINT2,NETO2,NR4A3,RAB11FIP1,NRG1,LRRK1,ATP1B3,FZD5,NDE1,TRAF5,TBC1D4,F2RL1,HSPB1,ABCG1 |
| 2.260e-07 | -15.30 | extracellular structure organization | biological process | GO:0043062 | 370 | 70 | 16441 | 1675 |
CASP3,LTBP1,HSPG2,P3H2,COL18A1,F11R,DDR1,PDGFB,SDC1,LTBP3,PDGFA,APLP2,CDH1,CTGF,NPNT,NTN4,CYP1B1,SULF2,TIMP2,COL6A2,LOXL2,DAG1,COL12A1,BMP1,ADAMTS14,CAPN1,COL9A3,LGALS3,ITGA6,LRP4,SDC4,SOX9,COL4A5,TGFBR1,ADAMTSL4,FBLN1,ELF3,ITGA3,ITGB8,CYR61,BMP7,COL6A1,CST3,EXOC8,ADAM15,WNT3A,NCAM1,CRTAP,ADAMTS2,FBLN5,ERO1A,FURIN,VWA1,COL7A1,NPHP3,CRISPLD2,PRDX4,MMP15,CTSL,COL13A1,PLOD2,ITGA7,SPINT2,CTSV,KLK7,LTBP2,ITGAV,PLOD3,COL16A1,TLL2 |
| 2.279e-07 | -15.29 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | 198 | 44 | 17758 | 1761 |
TXN,DLGAP5,LGALS3,S100A11,GNPDA1,PTTG1,EFHD2,MNS1,IL18R1,REPS1,KCTD9,HLA-A,TOP2A,CDKN2C,RRBP1,MDFIC,F2R,SNX10,S100A13,S100A6,PQLC3,PLSCR1,S100A4,CDC20,LITAF,GGH,NUSAP1,DOCK5,RNPEP,KIF11,CASP4,CDK1,PRDX4,GALNT3,NUCB1,CARHSP1,IDE,CDCA5,DBI,GEM,ARF6,CCNB2,E2F8,ACOT7 |
| 2.292e-07 | -15.29 | fibroblast growth factor receptor signaling pathway | biological process | GO:0008543 | 293 | 59 | 16441 | 1675 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,CALM3,NRG2,ERBB2,PSMD10,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,PDGFA,CALM2,PSMD1,ADRBK1,CTGF,SHC3,PTEN,FLRT3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,NR4A1,RAPGEF2,CALM1,CASP9,PIK3R1,GRIN1,PRKAR2B,AGO4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,JAK1,FGFR2,PHLPP2,ITPR1,NRG1,SPTBN5,GRIN2D,JAK3,GAB1 |
| 2.316e-07 | -15.28 | protein kinase regulator activity | molecular function | GO:0019887 | 132 | 34 | 16491 | 1673 |
CCNE2,CASP3,SPRED1,NKX3-1,CDKN1C,IQGAP1,DNAJC3,CALM3,TRIB2,CALM2,CDKN2C,CCND1,PIK3CA,CDKN1B,ERBB3,CDKN2D,SPRY2,CHP1,CKS2,CALM1,RGCC,PRKAR2B,MAPK8IP1,CDK5R1,SOCS3,CDK5RAP1,PRKAG2,GPRC5B,MADD,CAB39,NRG1,EFNA5,HSPB1,PKIA |
| 2.353e-07 | -15.26 | TTGTTT_V$FOXO4_01 | MSigDB lists | TTGTTT_V$FOXO4_01 | 1950 | 259 | 17758 | 1761 |
HSPG2,TSC22D3,CACNA2D2,IL18,CMTM6,GRM5,CDKN2C,SESN3,RGS3,IL31RA,KLF3,FOSB,KCNS3,TUBG1,CRY2,PIK3CD,MANF,ARMCX6,TIAM1,SMARCA2,SPATA18,SNTB2,SH3BGRL,LDB2,ZFAND5,NKD1,EIF4EBP2,E2F8,CDK17,MRC2,FRMD4A,NFKBIE,CDKN1C,RAB23,C6orf106,ISYNA1,TNFRSF19,MECOM,GNS,TFAP4,ITGA3,RALGPS2,FRY,SNX18,CYR61,ZNRF2,SLC16A6,FLRT3,BDH1,NCAM1,MAST4,KIF20A,NFIB,DHX32,PRKAG2,ETS2,SLC4A4,CSNK1G1,PELI2,ITPR1,AGBL5,SFMBT1,NR4A2,IFIH1,HOOK1,EHD1,DOCK9,CCDC109B,GRHL2,REPS2,THRA,DDIT4L,RGS20,RNF182,IL13RA1,ZNF385B,APPBP2,ZFYVE9,APLP2,RNF220,ST5,DACT1,CDKN1B,ACSL4,PDE4D,ETV4,SCN3A,DOCK4,LYRM1,SAT1,DNAJB14,ITPR3,H2AFV,ATP10D,SP4,FZD7,GABARAPL1,NFIX,PDLIM3,POPDC3,CORO1C,SIPA1L1,NRG1,SLC27A1,KLF5,NR3C2,IER5L,IGFBP6,PBX3,CYB561,SEPP1,ETS1,SRPX2,EFNB1,NEO1,SCML1,ITGB8,ANKS1B,MGAT4A,ERBB3,CITED2,TGIF1,LONRF3,BCL9,PIK3R1,NUB1,C2orf69,LRRC1,GPLD1,PITX2,NR4A3,ABCB1,JARID2,UGT8,ARFGEF1,F11R,PDGFB,DNER,KREMEN1,HTR1D,BTG3,IL6ST,TSPAN6,MITF,SLC44A1,ELF5,POF1B,NTN4,TLN2,BTBD3,PCGF5,TRIM8,CBX6,RGAG1,PRKRA,CXXC4,KLF12,HOXA9,LEMD1,MAFF,NR2C2,RMND5A,RUNX2,BMF,ZNF395,CHCHD7,ETV5,RAB6A,PHLPP1,DHRS3,IL18R1,IGF1R,GATA2,PIM1,PLCB2,CKAP4,ABCC1,DPYSL5,MGAT4B,C3orf58,RANBP9,PRX,G2E3,MUM1L1,XKRX,GNAS,KBTBD2,PLD1,SEMA3A,SHROOM2,TOB1,KLF7,LZTFL1,SORBS1,HOXB7,TP53,MORC4,SYTL2,CYP26A1,RAD23A,PDGFA,WDR44,LMO4,BCL6,DIXDC1,TWIST1,SEPHS1,SULF2,MAP3K3,PTPRU,SERTAD3,ERBB2IP,DUSP4,TLE1,VSIG10,C1orf43,BIN1,SORT1,CPEB4,KLHL13,GNE,FAM134A,GABRG2,HMGN3,COL4A5,INTS8,NRP2,SIRPA,PPP2R3A,HDAC9,FOXP2,CCDC92,ADORA1,FAM63A,GTF2F2,TFAP2A,SGK1,TSPAN13,CLIP2,RBMS2,WBP5,NFE2L3,SUN2,MOSPD2,NR3C1,NR4A1,AMFR,TCEAL8,PRDX4,CD83,FAT4,PGRMC1,FAM117A,HOXB13,GRAMD1C,CEP41,NDFIP1,PKIA,GOLGB1 |
| 2.367e-07 | -15.26 | immune response-regulating signaling pathway | biological process | GO:0002764 | 562 | 96 | 16441 | 1675 |
SPRED1,INPP5D,RPS6KA1,PSME2,ERBB2,NRG2,PSME1,ITPR2,PRKACA,CACNB4,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,ELMO2,SHC3,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,PDE4D,SCARA3,LGMN,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,TNIP1,ITCH,CASP9,CR2,AGO4,PRKCQ,CD40,DUSP4,ITPR3,IRS2,PLCG1,PTPRJ,JAK1,LIMK1,NOD2,SPTBN5,IRF7,NRG1,GAB1,DDX58,TNRC6C,THEMIS2,RASA2,PSMD10,BTN3A1,CALM3,TEC,NCKAP1,PHLPP1,FGF19,PIK3AP1,PTEN,BAX,MAPK11,ERBB3,NCAM1,CNPY3,SYK,RASGRF1,PSMB4,NR4A1,MICB,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,ELK1,FOS,BCAR1,PSMA4,RASA1,GPLD1,MAPKAPK2,CTSL,FGFR2,PELI2,PHLPP2,NFKBIA,ITPR1,NR4A3,GRIN2D,ARPC2,IFIH1,JAK3 |
| 2.387e-07 | -15.25 | immune system process | biological process | GO:0002376 | 2162 | 289 | 16441 | 1675 |
TXN,ADD1,LGR4,AK7,DNAJC3,RET,TAP1,NRG2,PSME1,IL18,DPP8,CALM2,PSMD1,AP1M2,ELMO2,IL31RA,PIK3CA,IRF2,TINAGL1,PIK3CD,TIPARP,APOBEC3G,ERAP2,SPEF2,TNIP1,CASP9,AGO4,PRKAR2B,F12,RNF19B,ENPP1,PLCG1,LIMK1,NOD2,DHTKD1,F2RL1,GAB1,DDX58,CDKN1C,THEMIS2,ITGA6,HLA-E,KIF23,HERC6,MERTK,MECOM,MARCH8,ITGA3,PIK3AP1,RPL39,DAPK1,CD70,NCAM1,ULBP2,NUP85,MICB,CALM1,ANO6,ELK1,PSMA4,RASA1,FAS,SEMA4D,PELI2,ITPR1,RAET1L,ARPC2,MAP3K5,IFIH1,TMEM173,SPRED1,NLRX1,THRA,INPP5D,RPS6KA1,FTH1,CD274,BCL2L1,PRKACA,TNFSF9,APOBEC3B,SP100,CDKN1B,DAB2IP,RTKN2,PDE4D,IFIT1,RASGEF1A,LGMN,SNX10,MX1,SEC23A,SEC61B,RIPK2,APOBEC3D,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,FZD7,CMTM7,IRS2,JAK1,DDOST,AXL,NRG1,TNRC6C,EPS8,BTN3A1,PDIA3,HERC5,APOBEC3H,PKN1,ETS1,FGF19,HLA-A,SIX4,SGPL1,CXCL16,FAM111A,CTSC,PTEN,BAX,ADAM15,MAPK11,ERBB3,CITED2,CNPY3,TRIM62,FARP2,RASGRF1,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,FBXO9,YES1,FOS,KIF11,GPLD1,DCTN6,PITX2,FGFR2,NR4A3,ERAP1,GRIN2D,ITGAV,GPER1,CENPE,LRRK1,FZD5,SLC25A38,MELK,JARID2,CASP3,EPAS1,F11R,ITPR2,CACNB4,PDGFB,TRIM68,SPTB,SUSD2,RPS6KA2,SHC3,SIVA1,MITF,TMEM143,DLG1,SCARA3,S100A13,RASGRP1,LAMP3,NLRP4,CD55,TRIM8,USP18,ITCH,NFE2L1,CR2,ARHGDIB,PRKRA,ANLN,HOXA9,RUNX2,LGALS3,BVES,HLA-F,RASA2,CALM3,NCKAP1,TEC,RAB6A,PHLPP1,IL18R1,IGF1R,GATA2,KIF13B,KCNN4,AHCY,HLA-C,WNT3A,PODXL2,BTN3A2,TCF7,EIF2AK1,IFIT3,FECH,MAPKAPK2,ONECUT1,CSF1,PHLPP2,NFKBIA,NLRC5,ATP1B3,JAK3,CCNB2,IFI6,HOXB7,IL15,PSME2,TP53,ERBB2,IL27RA,SLC7A2,EMP2,BCAP31,PDGFA,ARTN,LMO4,PLCG2,BCL6,OAS3,FRS3,MBP,AKT1,OSTM1,PTGER4,GLO1,CD40,DUSP4,SOCS3,TAPBP,PTPRJ,SECTM1,PTBP3,IRF7,SPTBN5,ANXA3,PSMD10,SELL,TGFBR1,SIRPA,HDAC9,CD109,TOP2A,ADRBK1,TRIM21,SYK,GCNT1,HES1,RHOA,RAB3B,PSMB4,IFITM3,NR4A1,RC3H2,RGCC,TTC7A,RUNX3,BCAR1,FOXL1,CD83,CTSL,HLA-B,SWAP70,BANK1,SCG2,TWSG1,DHRS2,CTSV,DTX4,PPP2R3C,GEM,ICOSLG,L1CAM |
| 2.425e-07 | -15.23 | GNF2_PCNA | MSigDB lists | GNF2_PCNA | 67 | 22 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,MYBL2,CDCA8,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,PLK4,AURKA,CENPE,CCNB2,ESPL1,MELK,CKS2 |
| 2.441e-07 | -15.23 | LIM_MAMMARY_STEM_CELL_UP | MSigDB lists | LIM_MAMMARY_STEM_CELL_UP | 462 | 81 | 17758 | 1761 |
MYL9,SPRED1,SORBS1,SSH1,HSPG2,EPAS1,COL18A1,CACNB4,FAM101B,CARD10,EPDR1,PLS3,PDGFA,CTGF,IL6ST,TRPC1,CDH3,TINAGL1,TMEM64,PTPRE,KCNIP3,SNTB2,TNS1,COL12A1,DPYSL3,DZIP1L,PGF,TRIM9,SLC25A4,AXL,BMP1,NRG1,SLC27A3,LIFR,PCOLCE,GOLIM4,IGFBP6,BVES,ITGA6,RUSC2,LRP4,ETV5,SLC1A3,FBLN1,ETS1,EFNB1,NRP2,SLC27A6,BMP7,CALD1,FJX1,TPST1,CD70,IGFBP2,C10orf54,SGCB,CHSY3,ADAMTS2,ELK3,LCA5,TACC1,GYLTL1B,PRICKLE1,COL7A1,ANTXR1,BCAR1,C3orf58,PRX,FAS,ARHGAP24,TIMP3,RND3,ISM1,MATN2,SLC4A3,NETO2,PCDH19,FHL1,GEM,OSR1,COL16A1 |
| 2.449e-07 | -15.22 | HALLMARK_INTERFERON_ALPHA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_ALPHA_RESPONSE | 94 | 27 | 17758 | 1761 |
MX1,PARP12,PLSCR1,RIPK2,IL15,IFITM3,PSME2,USP18,NUB1,TAP1,SELL,PSME1,SAMD9,IFIT3,HERC6,LGALS3BP,FAM46A,CSF1,NMI,TRIM21,IRF2,IRF7,HLA-C,CMPK2,IFIH1,PARP9,LAMP3 |
| 2.467e-07 | -15.21 | GTGCCAA,MIR-96 | MSigDB lists | GTGCCAA,MIR-96 | 287 | 57 | 17758 | 1761 |
SORT1,GRHL2,CPEB4,TSC22D3,CACNA2D2,RAB23,TGFBR1,ITPR2,MORF4L2,FAM81A,CACNB4,TTYH3,SH3KBP1,SLC9A2,HDAC9,B4GALNT1,TNS3,CABP1,MITF,KLF3,ABCA2,VAT1,TMBIM6,SNX16,ABCD1,NTN4,EPB41L4B,SLC39A10,MYRIP,BTBD3,SCYL3,MAP3K3,LAMP2,PHF20L1,PCGF5,CELSR2,TACC1,PTPN9,CBX6,EZR,LDB2,ZFAND5,BSDC1,ARHGAP24,GPRC5B,PLOD2,COL13A1,CSF1,LRIG1,NR4A3,RYK,ZNF704,OVOL1,EIF4EBP2,AIFM3,COBL,ABCA1 |
| 2.477e-07 | -15.21 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | 192 | 43 | 17758 | 1761 |
DLGAP5,HJURP,PTTG1,NDC80,CDCA8,CCNB1,STIL,FANCI,ATG4A,FUT8,PLK4,MPHOSPH9,MCCC2,CKS2,HMMR,PLK1,SHMT1,ZWINT,CENPA,KIF20A,ASPM,SEPT6,STAU2,CDC20,EZR,GGH,NUSAP1,DUSP4,KIF11,CDK1,PRIM1,FECH,AURKA,STK39,PIEZO1,CENPE,UBE2C,CCNB2,ESPL1,PKIA,MELK,DEF6,GOLGB1 |
| 2.477e-07 | -15.21 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | 192 | 43 | 17758 | 1761 |
LMO7,TSC22D3,TAP1,CYB561,CNTNAP2,FBXO6,ITPR2,MGST2,TRIB2,DHRS3,DENND2D,CARD10,LGALS3BP,DNAJB9,ARHGEF10L,CDKN2C,DOPEY2,STIM1,TPST1,KLC3,CLDN4,RAB20,RCAN3,DLG3,SCARA3,RASGRF1,ADCK3,PRKCQ,KCTD2,CYB5A,LRRC42,ARHGAP24,ALDH3B1,CARHSP1,ETS2,TJP3,FAAH,P4HA2,SPINT2,SH3BGRL2,STK39,EPB41L4A,ST3GAL1 |
| 2.510e-07 | -15.20 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1940 | 257 | 17775 | 1757 |
ACACB,RET,DHX8,NRG2,LACTB2,CARD10,GRM5,EPDR1,CDKN2C,WEE1,CYP1A1,PSMD1,FOSB,PIK3CA,PIK3CD,TIAM1,TIPARP,ACVR1C,CASP9,TMEM151A,PRKAR2B,SAV1,PPP1R14C,CCNF,POR,PIAS3,PLCG1,LRIG1,DHTKD1,HDAC1,TRAF5,HSPB1,GAB1,HOXC13,DDX58,RAB23,MERTK,PSIP1,MECOM,ZNRF2,NEK2,SOCS5,DDB2,STAT4,AMER1,ELK1,GNA11,RASA1,FAS,PRKAG2,ETS2,FAAH,ITPR1,FAM83D,FGD6,AURKA,NDE1,MAP3K5,XDH,PLA2G4A,SPRED1,IQGAP1,RALBP1,RNF182,BCL2L1,PRKACA,DDR1,REPS1,CCND1,MUC16,CDH1,CDKN1B,EPHB4,ETV4,SCN3A,FZD4,SEPT6,PRKCQ,PKMYT1,C15orf39,ITPR3,ZNF469,FZD7,PRDM11,EPHA10,IRS2,PPP2R5A,JAK1,SHROOM3,AXL,NRG1,MAPK12,IGFBP6,HERC5,CTSZ,PKN1,ETS1,FGF19,HLA-A,PDIA4,SCML1,WWP2,DIRAS3,DTX3L,FUT2,ANKS1B,CTSC,PTEN,FJX1,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERBB3,SPRY2,NCOA2,PARP9,PVRL4,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,FURIN,UBE2A,C2orf69,LRRC1,FOS,CNTNAP1,FGFR2,PPM1H,GRIN2D,FZD5,UNKL,CASP3,UGT8,PPM1J,EPHA4,DNER,PDGFB,KREMEN1,RPS6KA2,CNTRL,IMPAD1,MKRN3,MITF,DUSP10,NTN4,TLN2,MYBL1,S100A13,PLK1,CELSR2,USP18,ITCH,ROR1,LHFPL2,IDH1,ADRBK2,RHEB,EDNRA,MAN2A2,NEIL1,GPRC5B,HOXA9,RAB11FIP1,PIK3C2B,RAP1GAP,PRKAA2,LASP1,PARP12,RASA2,ETV5,OTUD1,IGF1R,GATA2,PIM1,ZRANB1,PLEKHA6,ELK3,SCRIB,HEATR5A,STEAP1,G2E3,MAPKAPK2,GNAS,NFKBIA,ALPK3,EGFL7,YOD1,PLD1,JAK3,RARG,USP43,LMO7,HOXB7,NF2,HDAC11,TP53,ERBB2,MRAS,STIL,PDGFA,SS18,PLCG2,BCL6,SRR,CDH3,TWIST1,NOTCH3,DVL2,MAP3K3,AKT1,PTGER4,DUSP4,CD40,FANCE,CASP4,DAG1,MAP3K6,SOCS3,STK38,PTK7,LIFR,ABCA1,CMAS,MACC1,FRMD6,TGFBR1,FZD6,SIRPA,PPP2R3A,BMP7,MYCL,SGK1,BUB1,SYK,HES1,PHF20L1,RHOA,ASPM,AMFR,RC3H2,OGDHL,MAML2,BCAR1,MAPK8IP1,FAT4,RND3,RAP2C,DTX4,ARRB1,OTUB2,GEM,ABCG1 |
| 2.510e-07 | -15.20 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1940 | 257 | 17775 | 1757 |
ACACB,RET,DHX8,NRG2,LACTB2,CARD10,GRM5,EPDR1,CDKN2C,WEE1,CYP1A1,PSMD1,FOSB,PIK3CA,PIK3CD,TIAM1,TIPARP,ACVR1C,CASP9,TMEM151A,PRKAR2B,SAV1,PPP1R14C,CCNF,POR,PIAS3,PLCG1,LRIG1,DHTKD1,HDAC1,TRAF5,HSPB1,GAB1,HOXC13,DDX58,RAB23,MERTK,PSIP1,MECOM,ZNRF2,NEK2,SOCS5,DDB2,STAT4,AMER1,ELK1,GNA11,RASA1,FAS,PRKAG2,ETS2,FAAH,ITPR1,FAM83D,FGD6,AURKA,NDE1,MAP3K5,XDH,PLA2G4A,SPRED1,IQGAP1,RALBP1,RNF182,BCL2L1,PRKACA,DDR1,REPS1,CCND1,MUC16,CDH1,CDKN1B,EPHB4,ETV4,SCN3A,FZD4,SEPT6,PRKCQ,PKMYT1,C15orf39,ITPR3,ZNF469,FZD7,PRDM11,EPHA10,IRS2,PPP2R5A,JAK1,SHROOM3,AXL,NRG1,MAPK12,IGFBP6,HERC5,CTSZ,PKN1,ETS1,FGF19,HLA-A,PDIA4,SCML1,WWP2,DIRAS3,DTX3L,FUT2,ANKS1B,CTSC,PTEN,FJX1,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERBB3,SPRY2,NCOA2,PARP9,PVRL4,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,FURIN,UBE2A,C2orf69,LRRC1,FOS,CNTNAP1,FGFR2,PPM1H,GRIN2D,FZD5,UNKL,CASP3,UGT8,PPM1J,EPHA4,DNER,PDGFB,KREMEN1,RPS6KA2,CNTRL,IMPAD1,MKRN3,MITF,DUSP10,NTN4,TLN2,MYBL1,S100A13,PLK1,CELSR2,USP18,ITCH,ROR1,LHFPL2,IDH1,ADRBK2,RHEB,EDNRA,MAN2A2,NEIL1,GPRC5B,HOXA9,RAB11FIP1,PIK3C2B,RAP1GAP,PRKAA2,LASP1,PARP12,RASA2,ETV5,OTUD1,IGF1R,GATA2,PIM1,ZRANB1,PLEKHA6,ELK3,SCRIB,HEATR5A,STEAP1,G2E3,MAPKAPK2,GNAS,NFKBIA,ALPK3,EGFL7,YOD1,PLD1,JAK3,RARG,USP43,LMO7,HOXB7,NF2,HDAC11,TP53,ERBB2,MRAS,STIL,PDGFA,SS18,PLCG2,BCL6,SRR,CDH3,TWIST1,NOTCH3,DVL2,MAP3K3,AKT1,PTGER4,DUSP4,CD40,FANCE,CASP4,DAG1,MAP3K6,SOCS3,STK38,PTK7,LIFR,ABCA1,CMAS,MACC1,FRMD6,TGFBR1,FZD6,SIRPA,PPP2R3A,BMP7,MYCL,SGK1,BUB1,SYK,HES1,PHF20L1,RHOA,ASPM,AMFR,RC3H2,OGDHL,MAML2,BCAR1,MAPK8IP1,FAT4,RND3,RAP2C,DTX4,ARRB1,OTUB2,GEM,ABCG1 |
| 2.683e-07 | -15.13 | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | 186 | 42 | 17758 | 1761 |
ARHGEF3,PARP12,VANGL1,PSME2,CENPI,PTTG1,TAP1,HERC5,PSME1,SAMD9,HERC6,LGALS3BP,HDAC9,SP100,TRIM21,IFIT1,SEMA3G,OAS3,FAR2,LAMP3,LAMP2,REC8,MX1,PPIF,B3GNT2,MMD,PLSCR1,USP18,SAT1,EIF5A2,DUSP4,IFIT3,FAS,HLA-B,TAPBP,PRPS2,NMI,RAB11FIP1,IRF7,CENPE,IFIH1,IFI6 |
| 2.683e-07 | -15.13 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 186 | 42 | 17758 | 1761 |
MRC2,LGALS3,NQO1,UGP2,DAP,ZCCHC24,NDRG2,IL13RA1,MRAS,NANS,SPR,TNS3,AP1M2,CTSC,MITF,CST3,DAPK1,ADCK2,TACSTD2,SLC16A5,CCDC88A,PDGFC,TIMP2,ACO1,TNS1,PCTP,ALCAM,CD83,FUCA1,MID1IP1,SERPINA1,H1F0,PRCP,CSF1,SPINT2,CLIP4,CLMN,ADIPOR1,LRRK1,FZD5,NRGN,CD33 |
| 2.886e-07 | -15.06 | HALLMARK_HEME_METABOLISM | MSigDB lists | HALLMARK_HEME_METABOLISM | 193 | 43 | 17758 | 1761 |
GCLM,BCAM,ADD1,ALDH6A1,HEBP1,CAST,BLVRB,ABCG2,FAM46C,SPTB,BMP2K,RAD23A,ATG4A,MARCH8,CA2,KLF3,MARCH2,MINPP1,IGSF3,TRAK2,LAMP2,CLCN3,ERMAP,NR3C1,GCLC,MPP1,FOXJ2,NFE2L1,HTATIP2,FBXO9,SLC11A2,EIF2AK1,TNS1,BLVRA,OPTN,ENDOD1,FECH,H1F0,GDE1,P4HA2,ADIPOR1,SLC25A38,RAP1GAP |
| 2.899e-07 | -15.05 | ACCAAAG,MIR-9 | MSigDB lists | ACCAAAG,MIR-9 | 479 | 83 | 17758 | 1761 |
CCNE2,LAMP1,SLC25A24,TRIM2,RET,TESK2,KCTD12,TGOLN2,FAM46C,CMTM6,GRHL1,OSBPL3,BCL6,ANKRD12,CNNM4,SNX16,GOT1,DIXDC1,PACSIN1,ZNF365,SCYL3,MAP3K3,SIRT1,PCGF5,CBX6,KIF1C,ERBB2IP,ATP1B1,ICMT,ALCAM,COL12A1,KLF12,P4HA2,DOLPP1,AXL,KLF5,REEP4,HOXC13,CTHRC1,SORT1,RUNX2,CPEB4,ZNF395,FRMD6,UBASH3B,CALB2,ARL4C,DSE,ANO1,SIX4,LMNA,M6PR,FRY,RNF128,FLRT3,RIMS3,GAD1,RIMS2,SOCS5,SNX7,PDGFC,PHF20L1,FURIN,PPARA,SCRIB,LRRC1,SPTLC2,C3orf58,MUM1L1,ARHGAP24,GALNT3,MAPKAPK2,ONECUT1,SLC6A6,AMMECR1,RAP2C,SH3BGRL2,SHROOM2,CPEB2,AFAP1,ACOT7,ESYT2,DOCK9 |
| 3.025e-07 | -15.01 | malignant_melanoma | COSMIC cancer mutations | malignant_melanoma | 16732 | 1698 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,PRDX4,SCRN2,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.088e-07 | -14.99 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6320 | 721 | 17775 | 1757 |
HECA,ACACB,KLK10,ADD1,AASS,AK7,HEXB,RET,CACNA2D2,FBXO2,LYNX1,DPP8,LTBP3,GRM5,EPDR1,CALM2,DAPK2,WEE1,MUC4,ALDH1A3,FUT1,TUBG1,CRY2,PIK3CD,TMEM37,RNF26,TIAM1,TIPARP,APOBEC3G,NWD1,SERTAD4,MTRF1L,LOXL2,CYP4F3,COL12A1,ABR,MID1IP1,DNM1L,ATP7B,LIMK1,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,GGA1,SOX9,MERTK,ELF3,ATG4A,FRY,FLRT3,FAM13B,RANBP1,PCYOX1,ALPK1,PANX2,ZMYM1,DGKG,NUP85,C9orf72,HPS3,PQLC3,KIF20A,SALL4,MYBL2,ELK1,NPHP3,SPTLC2,SFXN5,GNA11,STK17A,DHX32,PTPRF,CACHD1,SCARB2,SLC4A4,SETD3,AURKA,DRP2,ARPC2,ZNF502,TMEM173,RUSC1,ADAMTS16,EGLN1,ARHGAP11A,GRHL2,PAPSS2,C5orf30,PRKACA,APC2,TNFSF9,REPS1,ZNF385B,APPBP2,CDS1,RNF220,ST5,SCNN1A,CDH1,SP100,SH3BP1,ENPP5,RTKN2,ZNF365,MYT1,SCN3A,TMEM200B,ENPP4,SSH3,COL6A2,C6orf1,RIPK2,FZD4,PLEKHO1,SYNE2,HTATIP2,CDCA2,RAB38,DNAJB14,IRS2,PDLIM3,SHROOM3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PLEKHG1,PNPLA6,SLC25A30,MAPK12,CKAP2,OSGIN2,CTSZ,ANO9,NEO1,PDIA4,DIRAS3,ITGB8,IGSF9,CTSC,CALD1,FAM102A,IGFBP2,MAPK11,TPCN1,AMOTL2,ADAMTS2,PLSCR1,RAPGEF2,PIK3R1,MRS2,ELOVL3,GRIN1,MYEOV,CNTNAP1,GALNT3,RAB11FIP2,SYT7,ACVRL1,NR1D2,CENPE,ITGAV,FHL1,CMPK2,DCBLD1,MYL9,CCNI,BCAM,KIAA1462,TRIM2,EPAS1,PPM1J,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,LMCD1,TEX2,MGAT5B,ITPR2,HDAC6,SPTB,PLS3,SUSD2,MKRN3,PAPSS1,MITF,TMEM143,ABCA2,NTN4,TLN2,CCDC38,ZNF462,PLK1,MCTP1,ING1,CELSR2,CR2,ANLN,IDH1,SESN1,RHEB,DZIP1L,DPYSL3,KDM4D,TRIM9,MFAP3L,PLCH1,KLF12,MAP2,DOLPP1,PRKCDBP,PIK3C2B,EPB41L4A,PRKAA2,PARP12,RUNX2,RASA2,DNAJB2,ASAH1,RAB6A,CNTNAP2,NCKAP1,B4GALT4,FBLN1,IL18R1,TNS3,DAZAP1,UBE2Q2,IGF1R,RINL,EXOC8,AHCY,MDFIC,PIM1,FAR2,ALDH3A2,MPHOSPH9,ABCC1,DPYSL5,CHSY3,PCDH1,PLEKHA6,ZNF320,SCRIB,TCF7,EIF2AK1,IFIT3,ANKRD29,PRX,RASGRP2,MAPKAPK2,KBTBD2,ITGA7,P4HA3,NLRC5,LTBP2,PLD1,SEMA3A,NF2,HOXB7,UGP2,UPF3B,FOXM1,XYLT1,TP53,ERBB2,LPIN3,STIL,CYP26A1,SYTL2,RAD23A,TTC21B,WDR44,PLCG2,LHX6,BCL6,ZDHHC23,NOTCH3,DVL2,SULF2,SIRT1,TMTC1,ERLEC1,AKT1,CDC20,PTGER4,ACO1,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,ABHD12,RBL1,ADAMTS14,EFNA5,LTA4H,NDST3,MAN2B2,BIN1,PINK1,GOLIM4,CDH22,KLHL13,RUSC2,HAL,GNE,ERI2,GABRG2,GDF15,AIP,PPP2R3A,SLC9A2,NRP2,DNAJB9,SH2D4A,CD109,ALPP,LYPD6,UBE2J1,SGK1,ABCD1,KLF9,FAH,NFE2L3,RHOA,NR3C1,CCDC34,COL7A1,BCAR1,MAPK8IP1,DGKE,BANK1,CDKN2AIPNL,SMTNL2,SERPINA1,FAT4,TWSG1,SCG2,ZNF214,CDCA7L,TMC5,CLIP4,FAM117A,SH3BGRL2,NDFIP1,TBC1D4,HIPK3,ARHGEF9,GOLGB1,SUN1,GAA,PPP4R4,TTC39B,HSPG2,LGR4,VANGL1,TMEM41B,ATP8A1,PPFIBP2,PLXNA1,PJA2,SLC20A1,SLC9A7,CYP1A1,ANKS6,CTGF,ELMO2,FOSB,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,IRF2,HYLS1,MTMR11,RCAN3,METAP2,SGCE,SNTB2,HSPA12A,TNS1,SLC25A5,TP53I3,RBM47,GNPTAB,NKD1,LRIG1,BMP1,FAM110C,PRDM5,UNC5B,LZTS1,DDX58,MRPL44,FRMD4A,TBC1D1,TMEM55B,KIF23,C6orf106,NDUFA4,SLC1A3,TNFRSF19,PSIP1,MESDC2,MECOM,DOPEY2,ITGA3,SLC16A6,VASN,BDH1,AIM1,RUNDC3B,DAPK1,ADCK2,TPST1,PRKG1,SORL1,C8orf58,CACNA1D,PIKFYVE,SYTL3,RIMS2,TRAK2,SOCS5,IGSF3,EPB41L5,DDB2,KCNJ12,PRODH,PRSS23,ZNF84,MMD,TBC1D8B,ADCK3,AMER1,ANO6,NPC2,ANTXR1,GLT8D2,RASA1,MMP15,DGKH,PLEKHH2,TJP3,SLC4A3,FAM83D,AGBL5,FGD6,PCDH19,CABIN1,NR4A2,PER3,MAP3K5,HOOK1,IFIH1,SLC2A4,TCTN2,REPS2,DLGAP5,CEP70,TRIP10,ST14,NLRX1,CAST,IQGAP1,RALBP1,RPS6KA1,THRA,CCDC110,ATP2C2,SNN,MNS1,ZFYVE9,APOBEC3B,NOV,ZNF75D,CDKN1B,CNNM4,BRI3,EPHB4,PHKA2,LGMN,MYO5B,UTRN,SLC11A2,PKMYT1,ATP1B1,C15orf39,ITPR3,ALCAM,H2AFV,SP4,NIN,EPHA10,JAK1,CCDC149,KLF5,HS3ST3B1,COBL,WASF3,ARHGEF3,PCOLCE,DEPDC1,HAPLN3,EPS8,ARL4C,CCNJL,HERC5,EFHD2,APOBEC3H,SPR,DNAH3,SIX4,LGALS3BP,WWP2,RASSF8,AKIRIN1,E2F7,FAM111A,TMEM87B,RNF128,PTEN,FUT8,SGK3,ATP8B1,SLC44A2,ERBB3,CITED2,SPRY2,SLC16A5,FARP2,RASGRF1,ALDH2,SHMT1,ARAP2,LONRF3,ZC3H11A,ZKSCAN2,DIAPH2,LRRC1,AIF1L,FOS,CDK5RAP1,NUCB1,MAMDC4,FGFR2,ABCB1,CSTF2,FZD5,SLC25A38,NCAPG2,ARSB,ESPL1,MELK,DEF6,ESYT2,EXPH5,LTBP1,UGT8,HEBP1,MPP5,KREMEN1,TMC1,TRIM68,SH3KBP1,EPCAM,ARHGEF10L,SIPA1L2,RAB15,C7orf49,LRRC6,SIVA1,ANKFN1,DLG1,POF1B,AKR1B1,CTTN,SLC39A10,MYRIP,CYP1B1,ATL1,USP18,ITCH,RGAG1,CXXC4,MAN2A2,ZNF114,ARHGEF19,GPRC5B,HPSE,KCNK1,MADD,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,LRRFIP2,PYROXD2,ETV5,ADAMTSL4,ZNF432,CA2,COL6A1,LIMCH1,RFX5,C10orf54,ZRANB1,SLC12A2,GAD1,ETV7,ALS2CL,SNX7,ELK3,GYLTL1B,PDE5A,RNF113A,NUBP1,C3orf58,STEAP1,GNAS,XKRX,BCAR3,NUDT16,NFKBIA,SH3BP4,ALPK3,PITPNA,DONSON,SHROOM2,JAK3,RARG,PROM2,LMO7,SORBS1,FAM92A1,HDAC11,MORC4,COL18A1,TDRKH,SLC25A48,SETDB2,CYP4F11,KIF14,FRYL,RPN2,EPB41L4B,PDIA6,SCYL3,SEPHS1,MAP3K3,GCA,PTPRU,ERBB2IP,DUSP4,KCTD2,BFSP1,BHLHB9,SECTM1,TLE1,ABCA1,GLIS3,SORT1,ENO2,TSPAN15,FRMD6,LRP4,FAM134A,TGFBR1,COL4A5,SBF1,HMGXB4,TMEM63A,KIF5B,IRF2BPL,CARD8,TAF1B,LLGL2,A4GALT,MYCL,BMP7,TOX2,RRBP1,KIAA0319,ARVCF,IQGAP3,CLIP2,RBMS2,MYO5A,PGM1,SUN2,NR4A1,GCLC,ASPM,RC3H2,SYBU,FOXL1,LEPR,KLHL2,HLA-B,RND3,PRCP,ZMIZ1,GEM,L1CAM,AHR,ABCG1,SNPH |
| 3.121e-07 | -14.98 | HORIUCHI_WTAP_TARGETS_DN | MSigDB lists | HORIUCHI_WTAP_TARGETS_DN | 296 | 58 | 17758 | 1761 |
SPC25,PPP1R2,DEPDC1,DLGAP5,HJURP,FOXM1,CKAP2,PTTG1,NDC80,CDCA8,KIF23,NUF2,CCNB1,CENPN,LBR,TOP2A,APOBEC3B,KIF14,NEK2,AKR1B1,BUB1,TMEM64,ULBP2,CKS2,SEPHS1,LAMP2,HMMR,PLK1,RAB3B,SHMT1,CENPA,KIF20A,ASPM,PBK,CDC20,MYBL2,NUSAP1,CDCA2,GLO1,ANLN,H2AFV,SLC25A5,KIF11,CDK1,ZNF618,FECH,PGF,DNAJC10,FAM64A,FAM83D,AURKA,HMGA1,ARF6,ARSB,UBE2C,CCNB2,ESPL1,MELK |
| 3.134e-07 | -14.98 | GSE27786_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_DN | 187 | 42 | 17758 | 1761 |
ANXA3,FRMD4A,LRP4,SDC4,C6orf106,HMGN3,FBXO6,DHRS3,PRKACA,TMCC3,ATP6V0B,TNS3,RPL39,BRI3,TMBIM6,KLF9,ALPK1,C9orf72,ALDH2,CITED4,PQLC3,PLSCR1,LONRF3,GUSB,MPP1,SPATA13,KIF13A,ZBTB7B,RNF19B,RNPEP,FZD7,NFIX,SLC6A6,PTPRJ,HPSE,RBM47,TMEM30A,AXL,CDCA5,NFKBIZ,GEM,NXT2 |
| 3.134e-07 | -14.98 | GSE3982_BCELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_BCELL_VS_BASOPHIL_DN | 187 | 42 | 17758 | 1761 |
MRC2,REPS2,ATP2C2,OSGIN2,PBX3,COX6C,CA8,SIRPA,PSMD1,CYP1A1,FRY,RIMS3,OSBPL3,CST3,KLF3,DRAM1,CD9,SORL1,FAR2,MYRIP,PDGFC,MBP,FOXJ2,MPP1,PARP4,CDA,MTRF1L,PCTP,SOX13,PIAS3,FUCA1,GNAS,PPP2R5A,ETS2,SEMA4D,H1F0,DBI,ZDHHC7,TOB1,PTGES,JARID2,RRAGD |
| 3.147e-07 | -14.97 | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | 19 | 11 | 17758 | 1761 |
MX1,PLSCR1,CYR61,PLAUR,IRF7,TRMT2B,ERBB2IP,IFIT1,OAS3,MAFF,IFI6 |
| 3.240e-07 | -14.94 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 557 | 93 | 17758 | 1761 |
CCNE2,PPP4R4,GRHL2,PLXNA1,FAM46C,GRM5,RAB15,RNF220,ACAP2,GRHL1,WDR44,DPYSL2,MKRN3,VAT1,ESPN,PIK3CD,PDE4D,SLC39A10,SCN2A,ANO4,SCYL3,SCN3A,SIRT1,SEC23A,PCGF5,GALNT7,RAB38,PPP1R14C,PTGFRN,ZFAND5,DAG1,SP4,ARF4,EDNRA,SOCS3,HLF,CDK19,P4HA2,DOLPP1,TMOD2,GLCCI1,LIFR,SEMA6B,RUNX2,CPEB4,FRMD6,ITGA6,CIT,ZCCHC24,SOX9,PDCL,MIER3,SBF1,SIX4,NRP2,ZDHHC21,HDAC9,UBE2J1,KLF9,NCAM1,SGCB,ATP2B1,AMOTL2,SYPL1,KCNJ12,PGM1,MMD,LPGAT1,BCL9,EIF5A2,MBNL3,MYBL2,PRICKLE1,FNDC3A,NFIB,RASA1,GLCE,GALNT3,TIMP3,COL13A1,CSNK1G1,SETD3,RAP2C,PCDH19,FGD6,NR4A2,STK39,MAP3K5,CEP41,SEMA3A,CPEB2,RARG,TLL2 |
| 3.261e-07 | -14.94 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6322 | 721 | 17775 | 1757 |
HECA,ACACB,KLK10,ADD1,AASS,AK7,HEXB,RET,CACNA2D2,FBXO2,LYNX1,DPP8,LTBP3,GRM5,EPDR1,CALM2,DAPK2,WEE1,MUC4,ALDH1A3,FUT1,TUBG1,CRY2,PIK3CD,TMEM37,RNF26,TIAM1,TIPARP,APOBEC3G,NWD1,SERTAD4,MTRF1L,LOXL2,CYP4F3,COL12A1,ABR,MID1IP1,DNM1L,ATP7B,LIMK1,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,GGA1,SOX9,MERTK,ELF3,ATG4A,FRY,FLRT3,FAM13B,RANBP1,PCYOX1,ALPK1,PANX2,ZMYM1,DGKG,NUP85,C9orf72,HPS3,PQLC3,KIF20A,SALL4,MYBL2,ELK1,NPHP3,SPTLC2,SFXN5,GNA11,STK17A,DHX32,PTPRF,CACHD1,SCARB2,SLC4A4,SETD3,AURKA,DRP2,ARPC2,ZNF502,TMEM173,RUSC1,ADAMTS16,EGLN1,ARHGAP11A,GRHL2,PAPSS2,C5orf30,PRKACA,APC2,TNFSF9,REPS1,ZNF385B,APPBP2,CDS1,RNF220,ST5,SCNN1A,CDH1,SP100,SH3BP1,ENPP5,RTKN2,ZNF365,MYT1,SCN3A,TMEM200B,ENPP4,SSH3,COL6A2,C6orf1,RIPK2,FZD4,PLEKHO1,SYNE2,HTATIP2,CDCA2,RAB38,DNAJB14,IRS2,PDLIM3,SHROOM3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PLEKHG1,PNPLA6,SLC25A30,MAPK12,CKAP2,OSGIN2,CTSZ,ANO9,NEO1,PDIA4,DIRAS3,ITGB8,IGSF9,CTSC,CALD1,FAM102A,IGFBP2,MAPK11,TPCN1,AMOTL2,ADAMTS2,PLSCR1,RAPGEF2,PIK3R1,MRS2,ELOVL3,GRIN1,MYEOV,CNTNAP1,GALNT3,RAB11FIP2,SYT7,ACVRL1,NR1D2,CENPE,ITGAV,FHL1,CMPK2,DCBLD1,MYL9,CCNI,BCAM,KIAA1462,TRIM2,EPAS1,PPM1J,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,LMCD1,TEX2,MGAT5B,ITPR2,HDAC6,SPTB,PLS3,SUSD2,MKRN3,PAPSS1,MITF,TMEM143,ABCA2,NTN4,TLN2,CCDC38,ZNF462,PLK1,MCTP1,ING1,CELSR2,CR2,ANLN,IDH1,SESN1,RHEB,DZIP1L,DPYSL3,KDM4D,TRIM9,MFAP3L,PLCH1,KLF12,MAP2,DOLPP1,PRKCDBP,PIK3C2B,EPB41L4A,PRKAA2,PARP12,RUNX2,RASA2,DNAJB2,ASAH1,RAB6A,CNTNAP2,NCKAP1,B4GALT4,FBLN1,IL18R1,TNS3,DAZAP1,UBE2Q2,IGF1R,RINL,EXOC8,AHCY,MDFIC,PIM1,FAR2,ALDH3A2,MPHOSPH9,ABCC1,DPYSL5,CHSY3,PCDH1,PLEKHA6,ZNF320,SCRIB,TCF7,EIF2AK1,IFIT3,ANKRD29,PRX,RASGRP2,MAPKAPK2,KBTBD2,ITGA7,P4HA3,NLRC5,LTBP2,PLD1,SEMA3A,NF2,HOXB7,UGP2,UPF3B,FOXM1,XYLT1,TP53,ERBB2,LPIN3,STIL,CYP26A1,SYTL2,RAD23A,TTC21B,WDR44,PLCG2,LHX6,BCL6,ZDHHC23,NOTCH3,DVL2,SULF2,SIRT1,TMTC1,ERLEC1,AKT1,CDC20,PTGER4,ACO1,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,ABHD12,RBL1,ADAMTS14,EFNA5,LTA4H,NDST3,MAN2B2,BIN1,PINK1,GOLIM4,CDH22,KLHL13,RUSC2,HAL,GNE,ERI2,GABRG2,GDF15,AIP,PPP2R3A,SLC9A2,NRP2,DNAJB9,SH2D4A,CD109,ALPP,LYPD6,UBE2J1,SGK1,ABCD1,KLF9,FAH,NFE2L3,RHOA,NR3C1,CCDC34,COL7A1,BCAR1,MAPK8IP1,DGKE,BANK1,CDKN2AIPNL,SMTNL2,SERPINA1,FAT4,TWSG1,SCG2,ZNF214,CDCA7L,TMC5,CLIP4,FAM117A,SH3BGRL2,NDFIP1,TBC1D4,HIPK3,ARHGEF9,GOLGB1,SUN1,GAA,PPP4R4,TTC39B,HSPG2,LGR4,VANGL1,TMEM41B,ATP8A1,PPFIBP2,PLXNA1,PJA2,SLC20A1,SLC9A7,CYP1A1,ANKS6,CTGF,ELMO2,FOSB,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,IRF2,HYLS1,MTMR11,RCAN3,METAP2,SGCE,SNTB2,HSPA12A,TNS1,SLC25A5,TP53I3,RBM47,GNPTAB,NKD1,LRIG1,BMP1,FAM110C,PRDM5,UNC5B,LZTS1,DDX58,MRPL44,FRMD4A,TBC1D1,TMEM55B,KIF23,C6orf106,NDUFA4,SLC1A3,TNFRSF19,PSIP1,MESDC2,MECOM,DOPEY2,ITGA3,SLC16A6,VASN,BDH1,AIM1,RUNDC3B,DAPK1,ADCK2,TPST1,PRKG1,SORL1,C8orf58,CACNA1D,PIKFYVE,SYTL3,RIMS2,TRAK2,SOCS5,IGSF3,EPB41L5,DDB2,KCNJ12,PRODH,PRSS23,ZNF84,MMD,TBC1D8B,ADCK3,AMER1,ANO6,NPC2,ANTXR1,GLT8D2,RASA1,MMP15,DGKH,PLEKHH2,TJP3,SLC4A3,FAM83D,AGBL5,FGD6,PCDH19,CABIN1,NR4A2,PER3,MAP3K5,HOOK1,IFIH1,SLC2A4,TCTN2,REPS2,DLGAP5,CEP70,TRIP10,ST14,NLRX1,CAST,IQGAP1,RALBP1,RPS6KA1,THRA,CCDC110,ATP2C2,SNN,MNS1,ZFYVE9,APOBEC3B,NOV,ZNF75D,CDKN1B,CNNM4,BRI3,EPHB4,PHKA2,LGMN,MYO5B,UTRN,SLC11A2,PKMYT1,ATP1B1,C15orf39,ITPR3,ALCAM,H2AFV,SP4,NIN,EPHA10,JAK1,CCDC149,KLF5,HS3ST3B1,COBL,WASF3,ARHGEF3,PCOLCE,DEPDC1,HAPLN3,EPS8,ARL4C,CCNJL,HERC5,EFHD2,APOBEC3H,SPR,DNAH3,SIX4,LGALS3BP,WWP2,RASSF8,AKIRIN1,E2F7,FAM111A,TMEM87B,RNF128,PTEN,FUT8,SGK3,ATP8B1,SLC44A2,ERBB3,CITED2,SPRY2,SLC16A5,FARP2,RASGRF1,ALDH2,SHMT1,ARAP2,LONRF3,ZC3H11A,ZKSCAN2,DIAPH2,LRRC1,AIF1L,FOS,CDK5RAP1,NUCB1,MAMDC4,FGFR2,ABCB1,CSTF2,FZD5,SLC25A38,NCAPG2,ARSB,ESPL1,MELK,DEF6,ESYT2,EXPH5,LTBP1,UGT8,HEBP1,MPP5,KREMEN1,TMC1,TRIM68,SH3KBP1,EPCAM,ARHGEF10L,SIPA1L2,RAB15,C7orf49,LRRC6,SIVA1,ANKFN1,DLG1,POF1B,AKR1B1,CTTN,SLC39A10,MYRIP,CYP1B1,ATL1,USP18,ITCH,RGAG1,CXXC4,MAN2A2,ZNF114,ARHGEF19,GPRC5B,HPSE,KCNK1,MADD,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,LRRFIP2,PYROXD2,ETV5,ADAMTSL4,ZNF432,CA2,COL6A1,LIMCH1,RFX5,C10orf54,ZRANB1,SLC12A2,GAD1,ETV7,ALS2CL,SNX7,ELK3,GYLTL1B,PDE5A,RNF113A,NUBP1,C3orf58,STEAP1,GNAS,XKRX,BCAR3,NUDT16,NFKBIA,SH3BP4,ALPK3,PITPNA,DONSON,SHROOM2,JAK3,RARG,PROM2,LMO7,SORBS1,FAM92A1,HDAC11,MORC4,COL18A1,TDRKH,SLC25A48,SETDB2,CYP4F11,KIF14,FRYL,RPN2,EPB41L4B,PDIA6,SCYL3,SEPHS1,MAP3K3,GCA,PTPRU,ERBB2IP,DUSP4,KCTD2,BFSP1,BHLHB9,SECTM1,TLE1,ABCA1,GLIS3,SORT1,ENO2,TSPAN15,FRMD6,LRP4,FAM134A,TGFBR1,COL4A5,SBF1,HMGXB4,TMEM63A,KIF5B,IRF2BPL,CARD8,TAF1B,LLGL2,A4GALT,MYCL,BMP7,TOX2,RRBP1,KIAA0319,ARVCF,IQGAP3,CLIP2,RBMS2,MYO5A,PGM1,SUN2,NR4A1,GCLC,ASPM,RC3H2,SYBU,FOXL1,LEPR,KLHL2,HLA-B,RND3,PRCP,ZMIZ1,GEM,L1CAM,AHR,ABCG1,SNPH |
| 3.327e-07 | -14.92 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | 168 | 39 | 17758 | 1761 |
DDX58,PLA2G4A,ARHGEF3,PARP12,CDKN1C,PBX3,HERC5,SAMD9,HERC6,LGALS3BP,BMP2K,MECOM,DTX3L,CYP1A1,ITGB8,SLC27A6,FRAS1,IFIT1,OAS3,SCN2A,RAB27B,PARP9,MX1,ERMAP,PRSS23,USP18,KIF13A,ATP1B1,IFIT3,TRIM9,C19orf66,HOXA9,INPP4B,KLF5,IRF7,CMPK2,IFIH1,AHR,IFI6 |
| 3.332e-07 | -14.91 | non_seminoma | COSMIC cancer mutations | non_seminoma | 505 | 86 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,PTEN,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,BSDC1,STK17A,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK,GOLGB1 |
| 3.437e-07 | -14.88 | response to chemical | biological process | GO:0042221 | 3971 | 489 | 16441 | 1675 |
TXN,SSH1,ADD1,IL15RA,SLC25A13,DNAJC3,RET,FBXO2,NRG2,PSME1,IL18,PLXNA1,CCNB1,CMTM6,CALM2,TYMP,CYP1A1,SESN3,PSMD1,CTGF,STIM1,ELMO2,CYP2S1,IL31RA,KLF3,FOSB,STEAP2,PIK3CA,CLDN4,IRF2,SEMA3G,MANF,PIK3CD,TIAM1,TIPARP,ACVR1C,CASP9,AGO4,PRKAR2B,LOXL2,F12,CYP4F3,POR,ABR,AHRR,PIAS3,ENPP1,PLCG1,LIMK1,ATP7B,NOD2,HDAC1,EIF4EBP2,UNC5B,HSPB1,GAB1,FGD1,DDX58,SEMA6B,SCN5A,HLA-E,DGKQ,SOX9,MTL5,SLC1A3,TNFRSF19,LMNA,TFAP4,ITGA3,CYR61,MEGF8,VASN,FLRT3,DAPK1,TNFRSF12A,CD70,MYDGF,CACNA1D,NCAM1,NUP85,SOCS5,PAQR7,EPB41L5,GFPT1,PRODH,STAT4,MICB,CALM1,ANO6,ERO1A,EPHA1,ELK1,PSMA4,NFIB,RASA1,CYB5A,FAS,MMP15,NCOA3,PRKAG2,SEMA4D,MATN2,ITPR1,AURKA,NR4A2,ARPC2,MAP3K5,NUP58,TMEM173,EGLN1,EHD1,PLA2G4A,SPRED1,SLC2A4,NQO1,PAPSS2,THRA,RPS6KA1,RALBP1,IQGAP1,IL13RA1,MGST2,BCL2L1,CD274,PRKACA,CYP39A1,ZFYVE9,CCND1,NOV,ACAP2,CDH1,SP100,CDKN1B,DAB2IP,PDE4D,IFIT1,ACSL4,EPHB4,LRP11,DLG3,RASGEF1A,CDKN2D,SULT2B1,ETV4,NR2C1,SEMA3B,MX1,DOCK4,SEC61B,COL6A2,RIPK2,FZD4,PRKCQ,SLC11A2,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,IRS2,ALDH3B1,JAK1,DDOST,CDK19,NGFRAP1,STK26,WFS1,AXL,SLC27A1,NRG1,NR3C2,CBX7,MAPK12,ARHGEF3,TNRC6C,NKX3-1,EPS8,HERC5,FBXO6,ETS1,GSTP1,FGF19,EFNB1,HLA-A,NEO1,CXCL16,ADD3,CTSC,PTEN,CST3,FUT8,CD9,BAX,ATP8B1,TMBIM6,IGFBP2,MAPK11,ERBB3,CITED2,SPRY2,TRIM62,NCOA2,FARP2,OPLAH,RASGRF1,TGIF1,PDGFC,ARHGEF28,ALDH2,SHMT1,B3GNT2,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,FURIN,PARP4,AK4,YES1,FOS,GPLD1,CNTNAP1,PITX2,NUCB1,TIMP3,PLOD2,FGFR2,RAB11FIP2,NR1D2,ACVRL1,ABCB1,RYK,NR4A3,OSER1,GRIN2D,ITGAV,GPER1,CMPK2,FZD5,OSR1,ARSB,USF2,CPEB2,CYBRD1,MELK,RGMA,MYL9,EMX1,CASP3,UGT8,EPAS1,EPHA4,DNAJB11,F11R,ITPR2,HDAC6,CACNB4,PDGFB,SDC1,TRIM68,SPTB,HTR1D,ZFYVE16,CPNE2,RPS6KA2,NPNT,SHC3,ZCCHC12,IL6ST,DPYSL2,PAPSS1,ABCA2,DLG1,AKR1B1,TRPC1,DUSP10,NTN4,MYH14,S100A13,RASGRP1,SP5,CYP1B1,THRB,TRIM8,CITED4,USP18,NFE2L1,EZR,PRKRA,IDH1,RHEB,DPYSL3,MDK,KCNMB4,MAP2,WIPI1,MADD,CAB39,ADIPOR1,MYL12B,NR2C2,PCSK5,RRAGD,PRKAA2,GRN,RUNX2,LGALS3,DNAJB2,HLA-F,RASA2,ETV5,ABCG2,CALM3,PHLPP1,IL18R1,CA2,IGF1R,GATA2,COL6A1,AHCY,PIM1,C10orf54,HLA-C,WNT3A,ABCC1,CYP26B1,DPYSL5,RGMB,OXR1,STRADB,SCRIB,TCF7,PDK3,IFIT3,RANBP9,CDK5R1,RASGRP2,FECH,GNAS,MAPKAPK2,BCAR3,PHLPP2,CSF1,TMEM30A,NFKBIA,SH3BP4,YOD1,PITPNA,LTBP2,PLD1,JAK3,SEMA3A,COL16A1,RARG,IFI6,KLF7,GAS2L1,SLC25A24,SORBS1,UGP2,FOXM1,IL15,PSME2,PDIA5,TP53,COL18A1,ERBB2,IL27RA,ARHGEF16,CYP26A1,PDGFA,SS18,ATP6V0B,ARTN,CYP4F11,KIF14,PLCG2,SRR,CDH3,GOT1,TWIST1,RPN2,OAS3,EGLN3,F2R,PDIA6,CTDSP2,FRS3,CTH,SIRT1,PPIF,TIMP2,MBP,ERLEC1,AKT1,PTPRU,PTGER4,ACO1,ERBB2IP,DUSP4,CD40,MYL12A,CASP4,DAG1,ARHGAP35,SOCS3,ATP13A2,DNAJC10,DUOX1,IDE,ATP1A1,PTPRJ,RBL1,PTK7,EFNA5,SPTBN5,IRF7,CYP2U1,LTA4H,ABCA1,LIFR,CMTM4,COL9A3,ANXA3,GCLM,PINK1,SORT1,CPEB4,ARHGEF11,LRP4,GABRG2,PSMD10,SELL,TGFBR1,AES,GDF15,COL4A5,AIP,DNAJB9,NRP2,HDAC9,KIF5B,IL17RB,ADRBK1,BMP7,TOX2,TFAP2A,UBE2J1,TRIM21,KLF9,IQGAP3,SYK,MYO5A,GCNT1,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,NR4A1,GCLC,LITAF,PPARA,RGCC,RUNX3,GGH,BCAR1,BBS2,LEPR,CD83,CTSL,HLA-B,TWSG1,SCG2,DHRS2,NAT1,CTSV,PGRMC1,HOXB13,PLOD3,TBC1D4,PTGES,AHR,L1CAM,ARHGEF9,ABCG1,ARHGEF4 |
| 3.601e-07 | -14.84 | LEE_NEURAL_CREST_STEM_CELL_DN | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_DN | 113 | 30 | 17758 | 1761 |
ENPP4,DDB2,COL9A3,LZTFL1,PRSS23,CAPN6,GALNT12,CD82,SYNE2,ETV5,SAT1,ARL4C,COL4A5,GDF15,CNTNAP2,FOS,HLA-B,MFAP3L,BTG3,CA2,PLK2,BMP7,FJX1,FUT8,CD9,HLA-C,GRAMD1C,FZD5,SPRY2,MAFF |
| 3.632e-07 | -14.83 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 916 | 140 | 16491 | 1673 |
LTBP1,NMRK1,AK7,CAMKK1,RET,EPHA4,NANS,CAMK1D,CCNB1,DAPK2,WEE1,RPS6KA2,PASK,PAPSS1,DLG1,PIK3CA,PIK3CD,PLK1,ACVR1C,PBK,ROR1,STK17B,CDK1,ADRBK2,PRIM1,GNPTAB,LIMK1,PLK2,PIK3C2B,ITPKA,PRKAA2,LMTK3,CDK17,NUAK1,SOX9,DGKQ,ADCK5,TEC,MERTK,BMP2K,IGF1R,DAPK1,MAP3K9,ADCK2,PRKG1,NEK2,ALPK1,PIM1,PIKFYVE,DGKG,MAST4,MMD,ADCK3,TESK1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,PDIK1L,CDK5R1,STK17A,DGKH,MAPKAPK2,PRKAG2,UAP1,DCK,CSNK1G1,PRPS2,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,UGP2,PAPSS2,RPS6KA1,ERBB2,TESK2,GRK6,DDR1,PRKACA,CDS1,CCND1,PLK4,OAS3,EPHB4,PHKA2,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,RIPK2,PANK1,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,JAK1,CDK19,STK26,PTK7,AXL,STK38,MLKL,MAPK12,CMAS,PINK1,CIT,GNE,TGFBR1,TRIB2,PKN1,NRP2,ADRBK1,CDK16,FAM20B,SGK3,SGK1,BUB1,MAPK11,ERBB3,SYK,MPP1,AK4,NADK2,YES1,DGKE,ACVRL1,FGFR2,RYK,PGM2L1,LRRK1,CMPK2,HIPK3,MELK |
| 3.668e-07 | -14.82 | VANTVEER_BREAST_CANCER_ESR1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_DN | 228 | 48 | 17758 | 1761 |
BIN1,UGT8,NFKBIE,HJURP,UGP2,NF2,IL15RA,ST14,HAPLN3,TBC1D1,CDCA8,MRAS,GPSM2,SNN,STIL,SIRPA,APOBEC3B,BTG3,CTSC,SH3BP1,KCNN4,LMO4,DAPK1,UBE2J1,CDH3,BUB1,PIM1,PDIA6,LAMP3,PGM1,CENPA,PLSCR1,CYB5R2,CDC20,MYBL2,SLC35C1,TTC7A,ANLN,OPTN,GPRC5B,FAM64A,CORO1C,NMI,SLC2A6,PLEKHG1,ATP1B3,CCNB2,MELK |
| 3.771e-07 | -14.79 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 235 | 49 | 17758 | 1761 |
GRN,IL15RA,TRIP10,S100A11,IQGAP1,ASAH1,CRABP2,PKN1,GSTP1,DDR1,EFNB1,LTBP3,LGALS3BP,IER3,M6PR,GNS,ATP6V0B,CTGF,CYR61,CTSC,DPYSL2,LMO4,COL6A1,PAPSS1,PPP4R1,ADAM15,LGMN,S100A13,CYP1B1,TIMP2,COL6A2,RHOA,PLAUR,CDC20,LITAF,ARHGDIB,NPC2,PKMYT1,BLVRA,ITPR3,LHFPL2,STX3,STK38,KLF5,LTBP2,ATP1B3,GEM,ARPC2,TRAF5 |
| 3.788e-07 | -14.79 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 433 | 78 | 16441 | 1675 |
CCNE2,CASP3,SPRED1,AVPI1,IQGAP1,EPHA4,ERBB2,PDGFB,STIL,ERP29,CARD10,GRM5,CALM2,CCND1,PDGFA,CDKN2C,RGS3,DUSP10,CDKN1B,DAB2IP,CDKN2D,RASGRP1,DVL2,CKS2,PLK1,SIRT1,RIPK2,AKT1,FZD4,PRKAR2B,PKMYT1,CD40,DUSP4,CDK1,MAP3K6,PTPRJ,STK38,MADD,NOD2,CAB39,SLC27A1,RGS14,HSPB1,GAB1,CDKN1C,CALM3,PSMD10,HERC5,PKN1,TRIB2,GSTP1,DIRAS3,TFAP4,PTEN,BMP7,MAP3K9,SORL1,MDFIC,MAPK11,PIM1,IQGAP3,SYK,SPRY2,MDFI,RAPGEF2,CALM1,RGCC,PDE5A,CDK5R1,CDK5RAP1,MAPKAPK2,PRKAG2,ARRB1,FZD5,MAP3K5,UBE2C,HIPK3,PKIA |
| 3.875e-07 | -14.76 | axon development | biological process | GO:0061564 | 699 | 113 | 16441 | 1675 |
MYL9,SPRED1,PSME2,RPS6KA1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,ARTN,SHC3,DPYSL2,DLG1,TRPC1,DAB2IP,NTN4,EPHB4,MYH14,DLG3,RASGEF1A,ETV4,TIAM1,RASGRP1,FRS3,SEMA3B,ATL1,COL6A2,EZR,PRKCQ,ALCAM,MYL12A,DAG1,DPYSL3,ARHGAP35,EPHA10,IRS2,PLCG1,JAK1,MAP2,LIMK1,SLC9A6,EFNA5,NRG1,SPTBN5,UNC5B,COBL,MYL12B,COL9A3,SCN5A,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,PLPPR4,FGF19,EFNB1,NRP2,NEO1,KIF5B,IGF1R,PTEN,BMP7,FLRT3,MEGF8,COL6A1,ERBB3,CACNA1D,NCAM1,WNT3A,S100A6,FARP2,DPYSL5,RASGRF1,B3GNT2,ARHGEF28,RHOA,PSMB4,RGMB,RAPGEF2,CALM1,GRIN1,YES1,EPHA1,NFIB,RANBP9,PSMA4,CDK5R1,RASA1,CNTNAP1,SEMA4D,FGFR2,MATN2,RYK,PGRMC1,NR4A3,PITPNA,GRIN2D,NR4A2,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,KLF7,RGMA |
| 4.100e-07 | -14.71 | Adaptive Immune System | REACTOME pathways | R-HSA-1280218 | 668 | 111 | 8202 | 867 |
PSME2,INPP5D,TAP1,FBXO2,ERBB2,NRG2,RNF182,PSME1,CD274,ITPR2,PJA2,PDGFB,PRKACA,SH3KBP1,CALM2,PDGFA,RNF220,PSMD1,AP1M2,CDH1,STIM1,PLCG2,PIK3CA,CDKN1B,TRPC1,PIK3CD,LGMN,RASGRP1,ERAP2,SEC23A,SEC61B,RIPK2,AKT1,ITCH,CASP9,CDC20,PRKCQ,AGO4,CD40,ITPR3,ASB13,RNF19B,SOCS3,IRS2,TRIM9,PLCG1,TAPBP,PTPRJ,PPP2R5A,NRG1,RAP1GAP,GAB1,TNRC6C,MRC2,NFKBIE,KLHL13,HLA-E,HLA-F,ASB9,KIF23,PSMD10,SELL,PDIA3,CALM3,FBXO6,PHLPP1,FGF19,HLA-A,DTX3L,KIF5B,UBE2Q2,PTEN,PIK3AP1,CTSC,KLC3,UBE2J1,PRKG1,TRIM21,WWP1,ERBB3,HLA-C,SYK,PSMB4,KIF20A,NR4A1,MICB,CALM1,PIK3R1,UBE2A,YES1,KIF11,PSMA4,RASGRP2,DCTN6,CTSL,HLA-B,PVRL2,FGFR2,TRIM69,PHLPP2,NFKBIA,ITPR1,CTSV,ERAP1,CTSA,CENPE,ITGAV,FBXO27,ICOSLG,UBE2C,CD33 |
| 4.100e-07 | -14.71 | LY_AGING_MIDDLE_DN | MSigDB lists | LY_AGING_MIDDLE_DN | 16 | 10 | 17758 | 1761 |
PLK1,CENPA,FOXM1,CDC20,MYBL2,KIF23,CCNF,CCNB1,KIF11,UBE2C |
| 4.124e-07 | -14.70 | activation of protein kinase activity | biological process | GO:0032147 | 456 | 81 | 16441 | 1675 |
SPRED1,TXN,AVPI1,PSME2,CAMKK1,NRG2,ERBB2,PSME1,PRKACA,PDGFB,ERP29,EMP2,CARD10,SPTB,GRM5,CALM2,PDGFA,PSMD1,SHC3,KIF14,PIK3CA,DLG1,DAB2IP,RASGEF1A,F2R,RASGRP1,FRS3,MAP3K3,RIPK2,PRKAR2B,CDK1,MAP3K6,IRS2,PLCG1,GPRC5B,JAK1,STK26,MADD,NOD2,CAB39,EFNA5,SPTBN5,NRG1,GAB1,NKX3-1,PINK1,RASA2,CALM3,PSMD10,TGFBR1,PKN1,FGF19,ADORA1,MAP3K9,MDFIC,MAPK11,ERBB3,IQGAP3,NCAM1,SYK,CCDC88A,MDFI,PDGFC,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,RGCC,STRADB,PSMA4,RASA1,MAPKAPK2,PRKAG2,FGFR2,ARRB1,PPP2R3C,STK39,GRIN2D,MAP3K5,JAK3 |
| 4.181e-07 | -14.69 | GSE25087_FETAL_VS_ADULT_TREG_DN | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_DN | 163 | 38 | 17758 | 1761 |
HECA,ENO2,PPP1R2,AASS,UBASH3B,MORC4,ASAH1,ANKS1B,PAIP2B,SLC16A6,RUNDC3B,FXYD5,CDKN1B,SORL1,KLF9,SEMA3G,LRP11,CNPY3,MYLIP,C9orf72,SIRT1,LONRF3,FZD4,OSTM1,CXorf57,LITAF,DGKE,CDK5RAP1,IRS2,KLF12,COQ10A,SLC25A4,SEMA4D,NR1D2,DTX4,TOB1,DCBLD1,ABCG1 |
| 4.187e-07 | -14.69 | CTTTGA_V$LEF1_Q2 | MSigDB lists | CTTTGA_V$LEF1_Q2 | 1147 | 165 | 17758 | 1761 |
TRIM2,RET,CACNA2D2,MPP5,FAM101B,CARD10,CALM2,SUSD2,SESN3,ELMO2,NPNT,RGS3,SLC44A1,MITF,PHTF1,IL31RA,ELF5,KLF3,ANKFN1,STEAP2,DUSP10,TACSTD2,ZNF462,LAMP2,SMARCA2,PCGF5,SH3BGRL,NFE2L1,MTRF1L,RNF19B,CDK1,ABR,TRIM9,ENPP1,TMEM164,NKD1,BMP1,CAB39,AGFG2,EIF4EBP2,LEMD1,MAFF,RRAGD,ALDH6A1,CHCHD7,ETV5,C6orf106,CALM3,TNFRSF19,IL18R1,TSPAN7,PSIP1,MECOM,TFAP4,AIM1L,RALGPS2,SNX18,OSTF1,PIM1,FAR2,CKAP4,GFPT1,ELK3,PCDH1,TBC1D8B,CALM1,TCF7,PCTP,STEAP1,XKRX,DGKH,SLC4A4,UAP1,H1F0,COL13A1,KBTBD2,AGBL5,AURKA,SEMA3A,TOB1,PLA2G4A,LMO7,NCKAP5,SORBS1,HOXB7,MORC4,COL18A1,CD274,SYTL2,ZFYVE9,RCN1,PDGFA,ACAP2,ENPP5,BCL6,CDH3,DAB2IP,SCN3A,MBP,C6orf1,SLC39A8,SYNE2,PANK1,NUSAP1,GTF2A2,ASB13,ALCAM,SP4,FZD7,NFIX,CORO1C,OVOL1,TLE1,NRG1,EFNA5,AIFM3,LIFR,NDST3,TTC8,ANXA3,CTHRC1,CMAS,TM2D2,DCAF7,HAL,GABRG2,PBX3,ETS1,HOXB2,FGF19,SIX4,NRP2,NEO1,WWP2,FOXP2,C16orf74,ADD3,ADRBK1,ANKS1B,CTSC,BMP7,RRBP1,FUT8,SGK3,FAM63A,ABCD1,TSPAN13,IQGAP3,PVRL4,TGIF1,PLSCR1,PIK3R1,UBE2A,RUNX3,LRRC1,AIF1L,PRDX4,PITX2,SCG2,AMMECR1,NR4A3,PPP2R3C,RGMA,TLL2,GOLGB1 |
| 4.189e-07 | -14.69 | Signaling by PDGF | REACTOME pathways | R-HSA-186797 | 345 | 67 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,COL6A2,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,PPP2R5A,JAK1,SPTBN5,NRG1,GAB1,COL9A3,TNRC6C,RASA2,CALM3,PSMD10,COL4A5,PHLPP1,FGF19,ADRBK1,PTEN,COL6A1,ERBB3,NCAM1,PDGFC,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,FURIN,GRIN1,BCAR1,PSMA4,RASA1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,JAK3 |
| 4.206e-07 | -14.68 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 500 | 85 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,PLK4,EPHB4,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,MAP3K6,STK17B,ADRBK2,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,ADRBK1,IGF1R,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,ERBB3,PIM1,SYK,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,BSDC1,STK17A,MAPKAPK2,FGFR2,ACVRL1,AURKA,ALPK3,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK,GOLGB1 |
| 4.256e-07 | -14.67 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | 189 | 42 | 17758 | 1761 |
GRN,PINK1,LGALS3,ST14,TBC1D1,HLA-E,HLA-F,TSC22D3,BTN3A1,CTSZ,SLC1A3,SIRPA,SCML1,SGPL1,MARCH8,TYMP,METTL7A,TSPAN6,DACT1,BCL6,FAM63A,RAB20,LIMCH1,HLA-C,PTPRE,CKAP4,LAMP3,PDGFC,ARAP2,TIMP2,RIPK2,ADCK3,CBX6,SLC11A2,NPC2,CD83,PELI2,SLC2A6,RYK,ARRB1,CTSA,PLOD3 |
| 4.488e-07 | -14.62 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7542 | 843 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,MRPS15,AASS,AK7,SLC25A13,DNAJC3,RET,CACNA2D2,DHX8,NRG2,LACTB2,CA8,BARD1,FAM46C,CARD10,CMTM6,LTBP3,GRM5,EPDR1,DAPK2,KIAA1107,CABP1,PAQR5,ALDH1A3,KLF3,PIK3CD,TINAGL1,TIAM1,TIPARP,MGAT5,ERAP2,SPEF2,SMARCA2,SH3BGRL,MTRF1L,PRKAR2B,LOXL2,F12,PPP1R14C,CYP4F3,COL12A1,ABR,ENPP1,DNM1L,LIMK1,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RELL1,GAB1,SCN5A,FAM169A,GGA1,SLC36A4,TTYH3,LMNA,RAVER2,ATG4A,MARCH8,FRY,PAIP2B,FAM189A1,MEGF8,RIMS3,FAM13B,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,NCAM1,MYLIP,DGKG,NUP85,C9orf72,MCCC2,HPS3,SLC37A1,PQLC3,SALL4,STAT4,NPHP3,SPTLC2,PCTP,SFXN5,GNA11,DCP2,CYB5A,STK17A,DHX32,PTPRF,CACHD1,SLC4A4,SETD3,ITPR1,CLMN,AURKA,SERPINB1,XDH,ADAMTS16,EGLN1,DOCK9,MTM1,GRHL2,PAPSS2,RGS20,TESK2,PKP2,IL13RA1,PRKACA,TNFSF9,REPS1,ZNF385B,APPBP2,CDS1,MUC16,SCNN1A,CDH1,XYLT2,RTKN2,ACSL4,RASGEF1A,RAB27B,DLG3,SCN3A,ENPP4,MX1,SSH3,FZD4,PTPN9,SEPT6,SYNE2,CDCA2,NUSAP1,RAB38,ZNF618,PDLIM3,SHROOM3,CDK19,WFS1,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,RGS14,TTC8,HABP4,BTN3A1,CTSZ,ANO9,NUCB2,GSTP1,ETS1,SLC25A43,SRPX2,NEO1,PDIA4,FUT2,ITGB8,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,MGAT4A,KLC3,FAM102A,WWP1,MAPK11,AMOTL2,PVRL4,ADAMTS2,PLSCR1,FMN1,RAPGEF2,PIK3R1,MRS2,GRIN1,CXorf57,UBE2A,AK4,BLVRA,SNTB1,CRISPLD2,GALNT3,RAB11FIP2,NR1D2,ACVRL1,SYT7,PPM1H,CENPE,ITGAV,USF2,DCBLD1,CYBRD1,ACOT7,TLL2,TMEM131,BCAM,KIAA1462,EPAS1,GNPDA1,CNOT8,EPHA4,CUL4B,FHDC1,ARFGEF1,LMCD1,DNAJB11,TEX2,ITPR2,SDC1,SPTB,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,SHC3,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,ANO4,TLN2,MYBL1,DDX59,NEB,CCDC38,ZNF462,THRB,MCTP1,CD55,KCNIP3,CELSR2,CR2,PRKRA,ANLN,IDH1,SESN1,LHFPL2,RHEB,OPTN,PLEKHG6,TMEM164,HS6ST1,KLF12,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,RRAGD,RMND5A,PRSS8,PARP12,BMF,HJURP,LGALS3,UBASH3B,RASA2,ADCK5,CNTNAP2,NCKAP1,B4GALT4,FBLN1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,AHCY,MDFIC,FAR2,WNT3A,ABCC1,CHSY3,PCDH1,PLEKHA6,MGAT4B,SPATA13,SCRIB,TCF7,IFIT3,ANKRD29,G2E3,RASGRP2,EPN3,MAPKAPK2,PHLPP2,P4HA3,PRPS2,NLRC5,LTBP2,ATP1B3,PLD1,ZDBF2,SEMA3A,NIPA1,USP43,NF2,CTDSPL,TMX4,XYLT1,TP53,CCDC68,ERBB2,SLC7A2,STIL,SYTL2,PDGFA,TTC21B,WDR44,EFR3A,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,SCN2A,SULF2,CPD,SIRT1,CLCN3,TMTC1,MBP,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DUOX1,ATP1A1,IDE,PTPRJ,C19orf66,ABHD12,PTK7,ADAMTS14,EFNA5,SYT13,AIFM3,NDST3,MAN2B2,BIN1,COL9A3,PINK1,PACSIN2,TM2D2,GOLIM4,CDH22,CPEB4,KLHL13,MACC1,DAP,HAL,BLVRB,GABRG2,HMGN3,DSE,AIP,PARM1,SLC9A2,NRP2,SIRPA,DNAJB9,SH2D4A,ZDHHC21,CD109,LYPD6,GTF2F2,SGK1,TSPAN13,BUB1,ABCD1,KLF9,ATP2B1,GCNT1,FAH,IGDCC4,HMMR,DLGAP1,RHOA,FBLN5,NR3C1,CRB3,AMFR,PLAUR,STMN3,MAML2,COL7A1,FNDC3A,RNPEP,BBS2,CD83,PRDX4,BANK1,CDKN2AIPNL,FAT4,TWSG1,CDCA7L,TMC5,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,HIPK3,ARHGEF4,GOLGB1,LAMP1,SUN1,GAA,SLC35D2,PPP4R4,LGR4,HSPG2,SSH1,ATP8A1,TSC22D3,TAP1,PPFIBP2,PLXNA1,PJA2,SLC20A1,SLC9A7,SESN3,ANKS6,STIM1,RGS3,OSBPL3,FOSB,IL31RA,AOX1,PIK3CA,ATRNL1,SNX16,IRF2,MTMR11,TMEM68,ACVR1C,SNTB2,CASP9,HSPA12A,KIF13A,TNS1,GALNT7,LDB2,SAV1,CCNF,SPNS3,POR,AHRR,ANKRD10,GDE1,GNPTAB,LRIG1,NKD1,PRDM5,SERPINI1,NFKBIZ,TANC2,UNC5B,TRAF5,F2RL1,FGD1,DDX58,SEMA6B,MRC2,FRMD4A,SCOC,TBC1D1,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,TNFRSF19,DOPEY2,RALGPS2,PIK3AP1,ZNRF2,RUNDC3B,DAPK1,PRKG1,TMEM51,SORL1,CD70,CACNA1D,PIKFYVE,RIMS2,TRAK2,FAM69A,PMPCB,MMD,TBC1D8B,LPGAT1,CALM1,ANO6,ATP8B3,ANTXR1,NFIB,RASA1,STX3,FRMD4B,DGKH,GABRD,PRKAG2,PLEKHH2,TJP3,PELI2,AGBL5,FGD6,PCDH19,CABIN1,KLK7,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,NRBP1,FRMPD3,PLA2G4A,FOXO6,SPRED1,SLC2A4,TCTN2,CEP70,S100A11,ST14,IQGAP1,CAST,RALBP1,DDIT4L,ATP2C2,BCL2L1,TMEM170B,DDR1,MNS1,TMPRSS4,CYP39A1,ZFYVE9,ZNF75D,ACAP2,IFIT1,PDE4D,LGMN,PHKA2,SULT2B1,MED30,MYO5B,DOCK4,SEC23A,COG2,LYRM1,PANK1,UTRN,TMEM144,PRKCQ,PKMYT1,ITPR3,ALCAM,H2AFV,ATP10D,SP4,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,TSPAN18,ZNF704,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,CBX7,COBL,DENND5B,WASF3,IGFBP6,ATP9A,CCNJL,EFHD2,HERC5,PBX3,DNAH3,EFNB1,TEAD3,HLA-A,LGALS3BP,TMCC3,WWP2,AKIRIN1,SNTA1,E2F7,RNF128,PTEN,DRAM1,CD9,CNPY3,SPRY2,TRIM62,NCOA2,FARP2,RASGRF1,PDGFC,ALDH2,ARHGEF28,ARAP2,ZC3H11A,MPP1,PARP4,ZKSCAN2,DIAPH2,FBXO9,LRRC1,GRTP1,FOS,KIF11,CDK5RAP1,MAMDC4,FGFR2,TBX18,AMMECR1,ABCB1,ERAP1,CSTF2,ETAA1,WDR62,SLC25A38,ARSB,CPEB2,ESPL1,CXorf56,MELK,JARID2,ESYT2,EXPH5,EMX1,LTBP1,UGT8,HEBP1,CPT2,FLYWCH2,VARS2,MPP5,DNER,KREMEN1,TMC1,SH3KBP1,PTCHD4,CHPF,ARHGEF10L,NKAIN3,ZFYVE16,SIPA1L2,LRRC6,ARHGEF37,SIVA1,DPYSL2,TSPAN6,IMPAD1,ANKFN1,PHTF1,DLG1,POF1B,ANKRD12,SUN3,RAB20,CTTN,MYH14,TECR,SLC39A10,PTPRE,MYRIP,RASGRP1,LAMP3,ATL1,TRIM8,ITCH,ARHGDIB,ROR1,PTGFRN,ADRBK2,EDNRA,MAN2A2,HPSE,KCNK1,ADIPOR1,GLA,RAP1GAP,CPPED1,STARD3NL,NR2C2,CD99,LASP1,ARAP3,LRRFIP2,PYROXD2,CALM3,SAMD9,FAM81A,PHLPP1,LIMCH1,C10orf54,HLA-C,ZRANB1,NCEH1,SLC12A2,GAD1,ETV7,ALS2CL,CCDC88A,GYLTL1B,PDE5A,BTN3A2,MFSD7,RANBP9,MUM1L1,GNAS,BCAR3,XKRX,FECH,SLC6A6,UAP1,TMEM30A,ALPK3,RHOBTB2,PITPNA,SHROOM2,COL16A1,APOL2,SNX30,PROM2,LMO7,NCKAP5,SORBS1,FAM92A1,HDAC11,PDIA5,COL18A1,MRAS,PHLDA1,SLC25A48,SS18,SETDB2,KIF14,FRYL,REEP1,GOT1,RPN2,DIXDC1,EPB41L4B,PDIA6,SCYL3,FRS3,MAP3K3,GCA,SLC39A8,OSTM1,KCTD2,DOCK5,CASP4,ARHGAP35,ALDH5A1,BFSP1,TLE1,VSIG10,SPTBN5,ABCA1,LNP1,LIFR,GLIS3,ANXA3,FBLIM1,SORT1,ARHGEF11,TSPAN15,POC1B,LRP4,ARMC7,MIER3,TGFBR1,AES,NOTUM,TRMT2B,INTS8,FAM167A,TMEM63A,HDAC9,TOP2A,MDM1,ADORA1,TAF1B,ADRBK1,BMP7,TOX2,RRBP1,GALNS,IQGAP3,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,SUN2,GCLC,ASPM,RC3H2,SYBU,OGDHL,MBNL3,TTC7A,RUNX3,LEPR,FOXL1,KLHL2,ENDOD1,SWAP70,TRIM69,SPINT2,ARRB1,GRAMD1C,ZMIZ1,PLOD3,SOX8,AHR,RAB3IL1,ABCG1 |
| 4.609e-07 | -14.59 | cytoskeleton | cellular component | GO:0005856 | 1933 | 257 | 17570 | 1756 |
SSH1,ADD1,SYTL4,CCNB1,PJA2,FAM101B,CALM2,STIM1,CABP1,TUBG1,HYLS1,ZBTB18,SPEF2,SGCE,SMARCA2,KIFC2,SNTB2,PRKAR2B,KIF13A,TNS1,CCNF,SLC25A5,MID1IP1,DNM1L,PLK2,TRAF3IP1,FAM110C,NOD2,TMOD2,RELL1,HSPB1,TRAF5,FGD1,DDX58,FRMD4A,NUAK1,DGKQ,KIF23,LMNA,FRY,NEK2,DAPK1,MYLIP,NUP85,C9orf72,EPB41L5,KIF20A,CALM1,FRMD4B,PLEKHH2,FAAH,AGBL5,FAM83D,FGD6,AURKA,MDH1,STK39,DRP2,NDE1,ARPC2,CFAP20,HOOK1,RUSC1,FRMPD3,CEP70,TCTN2,DLGAP5,TMSB15A,TRIP10,RPS6KA1,ACTR8,IQGAP1,PKP2,BCL2L1,PRKACA,APC2,MNS1,APPBP2,SCNN1A,CDH1,PDE4D,ZNF365,SNX10,MYO5B,CAMSAP3,SSH3,RIPK2,CAPN6,SEPT6,SYNE2,CYS1,UTRN,KIF1C,NUSAP1,SP4,GABARAPL1,NIN,CEP162,PDLIM3,JAK1,SHROOM3,STK26,CORO1C,SIPA1L1,TRIOBP,RGS14,COBL,TTC8,WASF3,CKAP2,RASSF7,DNAH3,SNTA1,ADD3,RNF128,PHF7,CALD1,KLC3,SGCB,SPRY2,FARP2,LCA5,TACC1,FMN1,MPP1,PARP4,YES1,SNTB1,AIF1L,KIF11,DCTN6,NUCB1,GPER1,CENPE,WDR62,ESPL1,MYL9,NDRG2,F11R,HDAC6,SPTB,SH3KBP1,RPS6KA2,CNTRL,DPYSL2,CEP78,ABCA2,DLG1,CTTN,MYH14,RP2,TLN2,MYRIP,NEB,CCDC38,PLK1,PCGF5,STAU2,EZR,ARHGDIB,KLK6,ANLN,STK17B,CDK1,DPYSL3,DZIP1L,TRIM9,PLEKHG6,NEIL1,WIPI1,MAP2,EPB41L4A,MYL12B,PIFO,LASP1,BMF,ARAP3,CALM3,TEC,RINL,KIF13B,TBCD,LRIF1,MPHOSPH9,CKAP4,C9orf9,TPGS2,CORO2A,NUBP1,RANBP9,MAPKAPK2,H1F0,JAK3,CCNB2,SHROOM2,AFAP1,GAS2L1,DYNLRB1,SORBS1,UPF3B,NF2,STIL,TMSB15B,TTC21B,SS18,LRRC45,KIF14,PLK4,ESPN,NOTCH3,EPB41L4B,CHP1,AKT1,CDC20,CCSAP,DAG1,MYL12A,ARHGAP35,BFSP1,SPTBN5,REEP4,BIN1,FBLIM1,PACSIN2,PINK1,POC1B,FRMD6,CIT,CDCA8,PSMD10,TRIB2,SAC3D1,TOP2A,CCDC92,KIF5B,CDK16,LLGL2,TFAP2A,GTF2F2,CLIP2,MYO5A,PGM1,RHOA,CFAP46,ASPM,SYBU,RGCC,BBS2,BCAR1,ARHGAP24,KLHL2,UACA,PPP2R3C,GEM,CEP41,SNPH,DIS3L |
| 4.626e-07 | -14.59 | EGFR_UP.V1_UP | MSigDB lists | EGFR_UP.V1_UP | 183 | 41 | 17758 | 1761 |
GCLM,PAPSS2,IL15RA,EPAS1,ETV5,TAP1,CCDC68,PHLDA1,APOBEC3B,TNS3,ITGA3,CTGF,CYR61,MGAT4A,BMP7,DRAM1,AOX1,KCNS3,SNX16,CADPS2,EGLN3,SLC12A2,PTPRE,GCNT1,CYP1B1,SEC23A,ARAP2,ELK3,SAT1,LOXL2,DUSP4,IFIT3,LHFPL2,SPTLC2,CRISPLD2,ENPP1,ETS2,WIPI1,SLC9A6,MAP3K5,F2RL1 |
| 4.670e-07 | -14.58 | SANA_TNF_SIGNALING_UP | MSigDB lists | SANA_TNF_SIGNALING_UP | 80 | 24 | 17758 | 1761 |
MX1,CTHRC1,TNIP1,RIPK2,OXR1,SAT1,FTH1,SLC7A2,ANO9,LGALS3BP,HLA-A,HLA-B,TAPBP,CSF1,NFKBIA,DRAM1,IFIT1,OAS3,ITGAV,HLA-C,NCEH1,CMPK2,ICOSLG,IFIH1 |
| 4.699e-07 | -14.57 | Fc-epsilon receptor signaling pathway | biological process | GO:0038095 | 299 | 59 | 16441 | 1675 |
SPRED1,TNRC6C,PSME2,RASA2,CALM3,NRG2,ERBB2,PSMD10,PSME1,TEC,ITPR2,PHLPP1,PDGFB,SPTB,FGF19,PDGFA,CALM2,PSMD1,SHC3,PTEN,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,NR4A1,RAPGEF2,CALM1,CASP9,PIK3R1,GRIN1,PRKCQ,AGO4,ITPR3,FOS,PSMA4,RASA1,IRS2,PLCG1,JAK1,FGFR2,PHLPP2,NFKBIA,ITPR1,NR4A3,NRG1,SPTBN5,GRIN2D,JAK3,GAB1 |
| 4.857e-07 | -14.54 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | 1192 | 170 | 17758 | 1761 |
KIAA1462,SSH1,FAM199X,MRPS15,NDC80,DHX8,MPP5,CCNB1,SLC20A1,BARD1,CENPN,FANCI,WEE1,PSMD1,HSF2,UBE2T,OSBPL3,PAQR5,CEP78,PASK,STEAP2,TUBG1,HYLS1,NTN4,MYBL1,METAP2,PLK1,PCGF5,CENPA,STAU2,NBPF3,TNS1,ROR1,ICMT,LDB2,CCNF,ANLN,CDK1,RHEB,PRIM1,HS6ST1,GDE1,ZNF367,RAP1GAP,E2F8,NXT2,HJURP,PPP1R2,RAB23,KIF23,CNTNAP2,SLC1A3,GPSM2,RALGPS2,KIF13B,RANBP1,NEK2,MPHOSPH9,NUP85,C9orf72,GFPT1,DPYSL5,DDB2,MYBL2,SPATA13,C3orf58,STEAP1,RANBP9,MUM1L1,G2E3,CYB5A,DCP2,FAS,PTPRF,SLCO4A1,FAM64A,ETS2,UAP1,DCK,PHLPP2,PRPS2,CDCA5,FAM83D,AURKA,DONSON,ARPC2,HOOK1,CCNB2,NIPA1,CCNE2,SPC25,DLGAP5,FOXM1,PTTG1,PKP2,NUF2,RNF182,EMP2,KCTD9,CDS1,RAD23A,SS18,LMO4,KIF14,SRR,PLK4,BCL6,GOT1,ACSL4,CTH,SEPHS1,CPD,PPIF,FIGNL1,CDC20,NUSAP1,CDCA2,PKMYT1,XRCC6BP1,GTF2A2,ITPR3,PEX2,SIPA1L1,C1orf43,PPP2R2D,ISOC1,CMAS,DEPDC1,KLHL13,CKAP2,POC1B,ESRP1,CDCA8,ARL4C,PSMD10,SIRPA,TOP2A,KIF5B,AKIRIN1,FAM111A,E2F7,CTSC,ALG13,TOX2,FJX1,GTF2F2,WWP1,BUB1,IQGAP3,HMMR,PHF20L1,SHMT1,ZWINT,PLSCR1,TACC1,ASPM,PLAUR,CXorf57,CCDC34,C2orf69,KIF11,TIMP3,AMMECR1,NMI,PGRMC1,NETO2,NCAPG2,ESPL1,ACOT7,MELK |
| 4.930e-07 | -14.52 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 164 | 38 | 17758 | 1761 |
ENO2,ZNF395,SOX9,GDF15,PDGFB,PHLDA1,DDR1,S100A2,ELF3,ARTN,CYR61,DPYSL2,OPN3,SORL1,LIMCH1,ECE1,PIM1,EGLN3,CITED2,TIPARP,S100A6,CYP1B1,PGM1,NR3C1,PLAUR,S100A4,SAT1,AK4,LOXL2,FOS,CYB5A,SLCO4A1,P4HA2,ITPR1,MAFF,KLF7,RRAGD,EGLN1 |
| 4.948e-07 | -14.52 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 190 | 42 | 17758 | 1761 |
LGALS3,EPAS1,GNPDA1,CKAP2,UBASH3B,CDCA8,BARD1,HLA-A,NRP2,PDGFA,E2F7,PIK3AP1,OSBPL3,RANBP1,TOX2,NEK2,MANF,SGCB,SNX10,TIAM1,MYO5A,HMMR,PLSCR1,PBK,S100A4,CDC20,MBNL3,CCDC34,PIF1,PDK3,DUSP4,ANLN,FRMD4B,PRDX4,ENDOD1,CDCA5,PGRMC1,FHL1,GEM,NDE1,E2F8,MELK |
| 4.983e-07 | -14.51 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1523 | 213 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,CUL4B,EPHA4,RET,ARFGEF1,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,BARD1,ERP29,CARD10,SPTB,GRM5,FANCI,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PASK,PIK3CA,DLG1,SLC39A10,TIPARP,RASGRP1,PLK1,ACVR1C,ITCH,CASP9,EZR,PRKAR2B,F12,RNF19B,CDK1,PIAS3,PLCG1,GPRC5B,ANKRD6,PLK2,MADD,NKD1,NOD2,PRKCDBP,CAB39,HSPB1,F2RL1,GAB1,GGA1,DNAJB2,RASA2,SOX9,ASB9,CALM3,TEC,FBLN1,TFAP4,IGF1R,CYR61,DAPK1,MAP3K9,SORL1,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,MYLIP,CCDC88A,MDFI,SOCS5,MMD,MFI2,CALM1,PYM1,PDE5A,STRADB,PSMA4,RASA1,CDK5R1,FAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,NFKBIA,AURKA,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,DLGAP5,UPF3B,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,APC2,STIL,BCAP31,IER3,PDGFA,CCND1,ST5,DACT1,KIF14,BCL6,CDKN1B,DAB2IP,RASGEF1A,EGLN3,F2R,DVL2,FRS3,CHP1,MAP3K3,SIRT1,TIMP2,RIPK2,AKT1,FZD4,CDC20,PRKCQ,SLC11A2,CDCA2,CD40,MAP3K6,FZD7,IRS2,PPP2R5A,JAK1,STK26,NGFRAP1,WFS1,SLC27A1,EFNA5,NRG1,SPTBN5,MAPK12,PINK1,PCOLCE,NKX3-1,DAP,SDC4,PSMD10,TGFBR1,GDF15,PKN1,TRIB2,FGF19,PPP2R3A,CARD8,ADORA1,RNF128,CTSC,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,HES1,PDGFC,RASGRF1,RHOA,PSMB4,RAPGEF2,PLAUR,GCLC,NUB1,EIF5A2,GRIN1,RGCC,FURIN,PRICKLE1,YES1,GPLD1,BANK1,FGFR2,ACVRL1,RAP2C,NMI,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,NDFIP1,UBE2C,ESPL1,JARID2 |
| 5.032e-07 | -14.50 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 974 | 147 | 16441 | 1675 |
CASP3,UGT8,HSPG2,EPAS1,AK7,RET,IL18,MPP5,VASH1,TYMP,LRRC6,CTGF,STIM1,ELF5,ALDH1A3,PIK3CA,CYP1B1,DNAAF3,SPEF2,CELSR2,CASP9,TFAP2C,LOXL2,COL12A1,EDNRA,DZIP1L,PGF,HS6ST1,HPSE,TRAF3IP1,HDAC1,TMOD2,UNC5B,E2F8,ITGA6,SOX9,RAB23,NCKAP1,ITGA3,CYR61,COL6A1,TNFRSF12A,MYDGF,PIKFYVE,WNT3A,EPB41L5,ELK3,SALL4,SCRIB,EPHA1,NFIB,CDK5R1,GNAS,MMP15,ONECUT1,ETS2,PVRL2,ITGA7,EGFL7,RARG,EGLN1,EHD1,TCTN2,GRHL2,NF2,ST14,CAST,TP53,COL18A1,STIL,PRKACA,PDGFA,NOV,LMO4,BCL6,CNNM4,TWIST1,DAB2IP,NOTCH3,EPHB4,SNX10,DVL2,SIRT1,SAT1,HTATIP2,DUSP4,NFIX,CEP162,ARHGAP35,SHROOM3,PTK7,PNPLA6,KLF5,COBL,TTC8,CTHRC1,NKX3-1,TNRC6C,ADGRG1,POC1B,SDC4,TGFBR1,ETS1,SRPX2,SIX4,NRP2,FZD6,PPP2R3A,NEO1,CD109,E2F7,PTEN,BMP7,FJX1,TFAP2A,BAX,CD9,ATP8B1,ADAM15,CITED2,SYK,TGIF1,CFAP46,FMN1,NR4A1,PPARA,PRICKLE1,COL7A1,BBS2,GPLD1,CNTNAP1,ARHGAP24,SCG2,FGFR2,ACVRL1,TWSG1,PRCP,TBX18,SPINT2,NR4A3,ERAP1,HOXB13,ITGAV,SOX8,OSR1,FZD5,CEP41 |
| 5.106e-07 | -14.49 | BMI1_DN.V1_UP | MSigDB lists | BMI1_DN.V1_UP | 139 | 34 | 17758 | 1761 |
ANXA3,VANGL1,CD82,TAP1,DHRS3,TNFSF9,SRPX2,NRP2,SIRPA,B4GALNT1,CCND1,NOV,ITGA3,ITGB8,FJX1,TMEM51,SEMA3G,MICB,FURIN,COL7A1,LHFPL2,CRISPLD2,ATP13A2,MMP15,SLCO4A1,TIMP3,COL13A1,CSF1,LRIG1,SLC2A6,PIEZO1,FZD5,ABCA1,COL16A1 |
| 5.201e-07 | -14.47 | macromolecule modification | biological process | GO:0043412 | 3008 | 382 | 16441 | 1675 |
SSH1,RET,FBXO2,NRG2,PSME1,IL18,NANS,MORF4L2,CAMK1D,CCNB1,PJA2,BARD1,GRM5,CALM2,DAPK2,WEE1,PSMD1,MUC4,UBE2T,IL31RA,PALD1,PIK3CA,FUT1,CRY2,PIK3CD,MARCH2,TIPARP,MGAT5,APOBEC3G,METAP2,FBXL16,ACVR1C,PBK,LOXL2,GALNT7,ICMT,CCNF,MCFD2,RNF19B,POR,ARF4,PIAS3,PLK2,LIMK1,GNPTAB,PRDM5,NOD2,HDAC1,ITPKA,TRAF5,GAB1,CDK17,NUAK1,SOX9,HERC6,MERTK,TNFRSF19,BMP2K,RABGGTA,ATG4A,MARCH8,ZNRF2,PPP4R1,NEK2,TPST1,DAPK1,ADCK2,MAP3K9,PRKG1,OPN3,ALPK1,NCAM1,MAST4,MYLIP,NUP85,PPP6R1,SOCS5,TRAK2,GFPT1,DDB2,B3GNT7,MMD,STAT4,CALM1,ERO1A,EPHA1,ELK1,JADE2,PSMA4,RASA1,STK17A,MMP15,PTPRF,NCOA3,PRKAG2,PELI2,SETD3,CSNK1G1,AGBL5,AURKA,STK39,CDK18,MAP3K5,CFAP20,IFIH1,NRBP1,NUP58,RUSC1,EGLN1,SPRED1,MTM1,DLGAP5,GALNT12,INPP5D,RPS6KA1,TESK2,RNF182,GRK6,PRKACA,DDR1,CCND1,MUC16,RNF220,SP100,DOK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,ATG4D,SEC23A,SSH3,RIPK2,APOBEC3D,PTPN9,PRKCQ,PKMYT1,ASB13,XRCC6BP1,EPHA10,IRS2,JAK1,DDOST,CDK19,STK26,AXL,TRIOBP,TRABD2A,NRG1,MLKL,MAPK12,DCAF7,PDIA3,HERC5,CTSZ,APOBEC3H,FBXO6,PKN1,FGF19,WWP2,DTX3L,FUT2,RNF128,CTSC,ARSG,PTEN,MGAT4A,ALG13,FUT8,SGK3,WWP1,MAPK11,ERBB3,TRIM62,NCOA2,CRTAP,RASGRF1,B3GNT2,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,UBE2A,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,NEURL1B,FOS,ARSK,GALNT3,CDK5RAP1,PLOD2,FGFR2,ACVRL1,DBI,PPM1H,RYK,GRIN2D,ITGAV,LRRK1,ARSB,WDR45B,MELK,UNKL,TRIM2,PPM1J,CAMKK1,CUL4B,EPHA4,MGAT5B,HDAC6,PDGFB,TRIM68,SPTB,RPS6KA2,SHC3,MKRN3,PASK,DLG1,DUSP10,PTPRE,RASGRP1,PLK1,TRIM8,ITCH,USP18,ROR1,PRKRA,CDK1,ADRBK2,STK17B,KDM4D,TRIM9,MAN2A2,NEIL1,MSL1,UEVLD,WIPI1,P4HA2,DOLPP1,CAB39,CPPED1,PRKAA2,LMTK3,RASA2,UBASH3B,ASB9,CALM3,ADCK5,TEC,RAB6A,B4GALT4,PHLPP1,ADAMTSL4,B4GALNT1,B3GALNT1,OTUD1,UBE2Q2,IGF1R,MDFIC,PIM1,ZRANB1,GAD1,MDFI,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,G2E3,CDK5R1,GNAS,MAPKAPK2,NUDT16,UAP1,PLPP3,PHLPP2,KBTBD2,P4HA3,ZDHHC7,ALPK3,CTSA,YOD1,JAK3,RNF146,USP43,LMO7,IL15,P3H2,PSME2,HDAC11,CTDSPL,ERBB2,TDRKH,KBTBD11,PDGFA,SETDB2,ZDHHC12,PLK4,ZDHHC23,RPN2,EGLN3,LMAN1,F2R,CTDSP2,SCYL3,FRS3,CTH,SEPHS1,MAP3K3,PPIF,SIRT1,AKT1,PTPRU,CDC20,PTGER4,DUSP4,MAP3K6,SOCS3,JADE1,ATP1A1,PTPRJ,STK38,PTK7,PEX2,SPTBN5,ST3GAL1,ABCA1,MAN2B2,CMAS,PINK1,KLHL13,CIT,GNE,PSMD10,TGFBR1,NOTUM,TRMT2B,TRIB2,SBF1,POMGNT1,PPP2R3A,HDAC9,ZDHHC21,ADRBK1,CDK16,A4GALT,UBE2J1,SGK1,TRIM21,BUB1,IQGAP3,SYK,GCNT1,B3GALT6,RAB3B,PSMB4,PLAUR,AMFR,RC3H2,RUNX3,COL7A1,PELI3,MAPK8IP1,PRDX4,KLHL2,FUCA1,SERPINA1,TRIM69,SCG2,DTX4,ARRB1,OTUB2,PLOD3,CEP41,UBE2C,HIPK3 |
| 5.231e-07 | -14.46 | positive regulation of signaling | biological process | GO:0023056 | 1558 | 217 | 16441 | 1675 |
ILDR1,TXN,LGR4,EPHA4,RET,ARFGEF1,LMCD1,NRG2,PSME1,IL18,NENF,HDAC6,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,SIVA1,TSPAN6,IL31RA,AKR1B1,SLC39A10,MYRIP,S100A13,RASGRP1,CYP1B1,TRIM8,SH3BGRL,KLK6,PRKRA,CDK1,POR,RHEB,PLCG1,GPRC5B,HPSE,AGPAT2,DNM1L,ANKRD6,PLK2,MADD,NKD1,FAM110C,NOD2,PRKCDBP,ADIPOR1,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,RRAGD,LASP1,BMF,CDKN1C,SERPINE2,BVES,RASA2,SOX9,CALM3,SLC1A3,TNFRSF19,IL18R1,ANO1,KIAA1161,TFAP4,CA2,IGF1R,CYR61,PIK3AP1,KCNN4,MAP3K9,MDFIC,TNFRSF12A,MYDGF,C10orf54,NCAM1,ZRANB1,WNT3A,RIMS2,MDFI,KLK5,CALM1,AMER1,PDE5A,SCRIB,PSMA4,STX3,RASA1,FAS,GNAS,MAPKAPK2,SEMA4D,PELI2,CSF1,NLRC5,GDF11,MAP3K5,JAK3,TOB1,RNF146,RUSC1,XDH,SPRED1,SORBS1,AVPI1,IL15,PSME2,TP53,ERBB2,BCL2L1,EMP2,BCAP31,PDGFA,NOV,ST5,RNF220,DACT1,CDH3,DAB2IP,DIXDC1,ECE1,RASGEF1A,F2R,NR2C1,DVL2,FRS3,SULF2,CTH,MAP3K3,SIRT1,PPIF,TIMP2,RIPK2,AKT1,FZD4,S100A4,PRKCQ,ITPR3,CD40,MAP3K6,FZD7,IRS2,PTPRJ,JAK1,AXL,SECTM1,NRG1,IRF7,SPTBN5,RGS14,PINK1,NKX3-1,CD63,ADGRG1,TSPAN15,EPS8,PDIA3,PSMD10,TGFBR1,GDF15,PKN1,FGF19,PPP2R3A,NEO1,KIF5B,ADORA1,CTSC,PTEN,BMP7,BAX,PLEKHF1,SLC44A2,BUB1,MAPK11,ERBB3,CITED2,IQGAP3,SYK,TRIM62,SPRY2,HES1,RASGRF1,RAB3B,RHOA,PSMB4,ASPM,RAPGEF2,PLAUR,PIK3R1,RC3H2,GRIN1,LITAF,FURIN,MAPK8IP1,GPLD1,CNTNAP1,BANK1,FGFR2,ACVRL1,TWSG1,DBI,RYK,ARRB1,GRIN2D,GPER1,LRRK1,FZD5,NDFIP1,L1CAM |
| 5.238e-07 | -14.46 | circulatory system development | biological process | GO:0072359 | 774 | 122 | 16441 | 1675 |
CASP3,GAA,GRHL2,HSPG2,EPAS1,FOXM1,PKP2,ERBB2,COL18A1,IL18,CCNB1,VASH1,STIL,PDGFB,PDGFA,TYMP,NOV,RPS6KA2,SETDB2,CTGF,LMO4,PIK3CA,TWIST1,DAB2IP,ECE1,EPHB4,NOTCH3,TIPARP,DVL2,CYP1B1,MAP3K3,SIRT1,SMARCA2,AKT1,FZD4,SAT1,HTATIP2,LOXL2,SAV1,ZFAND5,EDNRA,SOCS3,PGF,HS6ST1,PTPRJ,PDLIM3,HPSE,TRAF3IP1,PNPLA6,KLF5,NRG1,UNC5B,E2F8,GAB1,PCSK5,SCN5A,NKX3-1,BVES,ADGRG1,SOX9,TGFBR1,NCKAP1,DHRS3,ETS1,FGF19,SRPX2,NRP2,LMNA,HDAC9,SGPL1,MECOM,E2F7,ITGA3,ADRBK1,ITGB8,PTEN,CYR61,GATA2,FLRT3,MEGF8,BAX,ADAM15,TNFRSF12A,ERBB3,MYDGF,WNT3A,CITED2,SGCB,SYK,HES1,ELK3,SALL4,NR4A1,RAPGEF2,PPARA,EPHA1,NPHP3,FOXL1,GNA11,C3orf58,RASA1,GPLD1,ARHGAP24,PITX2,FAT4,FGFR2,SCG2,ACVRL1,PRCP,ITGA7,PLPP3,TBX18,ERAP1,ALPK3,EGFL7,HOXB13,ITGAV,FZD5,OSR1,ZMIZ1,AHR,EGLN1 |
| 5.238e-07 | -14.46 | cardiovascular system development | biological process | GO:0072358 | 774 | 122 | 16441 | 1675 |
CASP3,GAA,GRHL2,HSPG2,EPAS1,FOXM1,PKP2,ERBB2,COL18A1,IL18,CCNB1,VASH1,STIL,PDGFB,PDGFA,TYMP,NOV,RPS6KA2,SETDB2,CTGF,LMO4,PIK3CA,TWIST1,DAB2IP,ECE1,EPHB4,NOTCH3,TIPARP,DVL2,CYP1B1,MAP3K3,SIRT1,SMARCA2,AKT1,FZD4,SAT1,HTATIP2,LOXL2,SAV1,ZFAND5,EDNRA,SOCS3,PGF,HS6ST1,PTPRJ,PDLIM3,HPSE,TRAF3IP1,PNPLA6,KLF5,NRG1,UNC5B,GAB1,E2F8,PCSK5,SCN5A,NKX3-1,BVES,ADGRG1,SOX9,TGFBR1,NCKAP1,DHRS3,ETS1,FGF19,SRPX2,NRP2,LMNA,HDAC9,SGPL1,MECOM,E2F7,ITGA3,ADRBK1,ITGB8,PTEN,CYR61,GATA2,FLRT3,MEGF8,BAX,ADAM15,TNFRSF12A,ERBB3,MYDGF,WNT3A,CITED2,SGCB,SYK,HES1,ELK3,SALL4,NR4A1,RAPGEF2,PPARA,EPHA1,NPHP3,FOXL1,GNA11,C3orf58,RASA1,GPLD1,ARHGAP24,PITX2,FAT4,FGFR2,SCG2,ACVRL1,PRCP,ITGA7,PLPP3,TBX18,ERAP1,ALPK3,EGFL7,HOXB13,ITGAV,FZD5,OSR1,ZMIZ1,AHR,EGLN1 |
| 5.267e-07 | -14.46 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 133 | 33 | 17758 | 1761 |
ZMAT1,TSC22D3,TMX4,HABP4,ARL4C,PBX3,TGFBR1,TGOLN2,SEPP1,PSIP1,BEX2,BMP2K,DNAJB9,SCML1,RASSF8,NOV,DPYSL2,TOX2,SGK1,ACSL4,SGCB,MYO5A,ALDH2,PQLC3,PRKCQ,ALCAM,ZFAND5,GABARAPL1,SOCS3,DNAJC10,PER3,PTGES,CYBRD1 |
| 5.267e-07 | -14.46 | SERVITJA_LIVER_HNF1A_TARGETS_UP | MSigDB lists | SERVITJA_LIVER_HNF1A_TARGETS_UP | 133 | 33 | 17758 | 1761 |
SORBS1,CDKN1C,NQO1,CDCA8,MGST2,CCNB1,SLC20A1,TNFRSF19,WEE1,ADORA1,NPNT,NEK2,TNFRSF12A,BUB1,ALDH3A2,HMMR,KIF20A,MMD,SEPT6,CDC20,ANLN,PCTP,KIF11,POR,LEPR,GPRC5B,SLC25A4,ABCB1,PER3,CCNB2,SERPINB1,UBE2C,RRAGD |
| 5.354e-07 | -14.44 | endoplasmic reticulum | cellular component | GO:0005783 | 1604 | 219 | 17570 | 1756 |
IL15RA,ATP8A1,DNAJC3,EPHA4,TAP1,FBXO2,DNAJB11,ITPR2,VASH1,PJA2,PDGFB,ERP29,ABCD4,CYP1A1,STIM1,METTL7A,OSBPL3,CYP2S1,PHTF1,DLG1,MARCH2,TECR,SCARA3,TRAM1,RASGRP1,ERAP2,CYP1B1,ATL1,KCNIP3,STAU2,NFE2L1,KLK6,ICMT,MCFD2,PTGFRN,CYP4F3,POR,RHEB,COL12A1,AGPAT2,MAP2,P4HA2,DOLPP1,SARAF,PIK3C2B,PIEZO1,SCN5A,FAM213B,FXYD3,HLA-E,HLA-F,ADAMTSL4,DHRS3,MESDC2,FLRT3,COL6A1,SUCO,SORL1,SELK,HLA-C,MYDGF,FAR2,WNT3A,NCEH1,ALDH3A2,CCDC88A,CKAP4,KDELR1,FAM69A,CYP26B1,FADS2,PQLC3,LPGAT1,ERO1A,PIP4K2C,EMC2,NPC2,ATP8B3,SPTLC2,CYB5A,COL13A1,FAAH,PLPP3,MFSD2A,TMEM30A,P4HA3,ITPR1,ZDHHC7,CTSA,PLD1,MAP3K5,APOL2,COL16A1,TMEM173,XDH,PLA2G4A,P3H2,CAST,XYLT1,PDIA5,TP53,COL18A1,MGST2,LPIN3,CYP39A1,BCAP31,CYP26A1,CDS1,RCN1,PDGFA,CYP4F11,ZDHHC12,XYLT2,REEP1,ZDHHC23,RPN2,NOTCH3,TMEM64,ACSL4,MINPP1,LMAN1,SULT2B1,SNX10,PDIA6,CHP1,SEMA3B,SULF2,MX1,SEC23A,SEC61B,ERLEC1,COL6A2,EVA1A,SYNE2,C3orf52,ACO1,KIF1C,RAB38,DNAJB14,PKMYT1,ITPR3,TRIQK,ATP10D,CASP4,GABARAPL1,TAPBP,DNAJC10,ATP1A1,DDOST,SLC9A6,WFS1,PNPLA6,SLC27A1,CYP2U1,REEP4,AIFM3,NR3C2,COL9A3,SORT1,CPEB4,PDIA3,CTSZ,COL4A5,NKRF,FBXO6,CRABP2,DSE,NUCB2,LBR,DNAJB9,HLA-A,ZDHHC21,SGPL1,PDIA4,ADORA1,RNF128,CTSC,ARSG,ALG13,CST3,RRBP1,BAX,UBE2J1,SGK1,ATP8B1,TMBIM6,CNPY3,MYO5A,CRTAP,PDGFC,RHOA,AMFR,PLAUR,PIK3R1,EIF5A2,ELOVL3,GRIN1,FURIN,COL7A1,FOS,ARSK,TXNDC11,MAPK8IP1,PRDX4,HLA-B,NUCB1,SERPINA1,PLOD2,DBI,PGRMC1,ERAP1,GPER1,SPCS3,PLOD3,ARSB,PTGES,ESYT2,ABCG1,RGMA |
| 5.357e-07 | -14.44 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 224 | 47 | 17758 | 1761 |
REPS2,ZNF395,CDKN1C,TSC22D3,FAM134A,EFHD2,PHLPP1,DDR1,C11orf95,TNFSF9,DNAJB9,ELF3,PTEN,KCNN4,FAM13B,MAP3K9,BAX,EPHB4,PIM1,EPB41L4B,CITED2,CTH,AMOTL2,DDB2,SAT1,NFE2L1,CDA,CCNF,FRMD4B,SOX13,FAS,GABARAPL1,MAPKAPK2,GNAS,TIMP3,ETS2,NR1D2,H1F0,AXL,P4HA2,PLK2,ERAP1,FHL1,SPCS3,LIFR,HOXC13,EHD1 |
| 5.391e-07 | -14.43 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | 184 | 41 | 17758 | 1761 |
COL9A3,TXN,IL15RA,ENO2,IL15,PSME2,TSC22D3,TAP1,COL4A5,NRP2,B4GALNT1,TOP2A,BTG3,ZNF75D,CYR61,FAM102A,DIXDC1,TAGLN2,SGCB,TIAM1,SLC12A2,FAM69A,LAMP3,IFITM3,STAT4,RAPGEF2,SAT1,AK4,EIF2AK1,DUSP4,IFIT3,CYB5A,SOCS3,CD83,TRIM9,PLK2,NFKBIA,NR4A3,LTBP2,TRAF5,KLF7 |
| 5.514e-07 | -14.41 | protein metabolic process | biological process | GO:0019538 | 4189 | 511 | 16441 | 1675 |
KLK10,SSH1,ADD1,HSPG2,MRPS15,DNAJC3,HEXB,RET,FBXO2,NRG2,PSME1,IL18,NANS,MORF4L2,CAMK1D,CCNB1,DPP8,PJA2,BARD1,GRM5,CALM2,DAPK2,WEE1,PSMD1,MUC4,UBE2T,IL31RA,PALD1,PIK3CA,FUT1,CRY2,TINAGL1,PIK3CD,MARCH2,TIPARP,MGAT5,ERAP2,METAP2,FBXL16,TNIP1,SPATA18,ACVR1C,PBK,CASP9,MTRF1L,LOXL2,F12,GALNT7,ICMT,CCNF,MCFD2,RNF19B,POR,ARF4,PIAS3,PLK2,LIMK1,GNPTAB,PRDM5,NOD2,BMP1,HDAC1,EIF4EBP2,MRPS28,ITPKA,TRAF5,GAB1,CDK17,MRPL44,GGA1,NUAK1,SOX9,HERC6,MERTK,TNFRSF19,BMP2K,LMNA,RABGGTA,ATG4A,MARCH8,ZNRF2,RPL39,PPP4R1,NEK2,TPST1,DAPK1,PCYOX1,ADCK2,MAP3K9,PRKG1,OPN3,SORL1,ALPK1,MYDGF,NCAM1,MAST4,MYLIP,NUP85,PPP6R1,SOCS5,TRAK2,GFPT1,DDB2,PMPCB,B3GNT7,KLK5,MMD,PRSS23,STAT4,CALM1,ERO1A,EPHA1,ELK1,TP53INP2,JADE2,PSMA4,RASA1,FAS,STK17A,MMP15,PTPRF,NCOA3,PRKAG2,TIMM8A,PELI2,SETD3,CSNK1G1,AGBL5,AURKA,STK39,KLK7,CDK18,MAP3K5,CFAP20,IFIH1,NRBP1,NUP58,RUSC1,XDH,ADAMTS16,EGLN1,SPRED1,MTM1,DLGAP5,ST14,GALNT12,INPP5D,RPS6KA1,PTTG1,TESK2,PRSS22,RNF182,GRK6,MVB12B,PRKACA,DDR1,TMPRSS4,ZFYVE9,CCND1,MUC16,RNF220,SP100,DOK4,XYLT2,CDKN1B,DAB2IP,EPHB4,PHKA2,RASGEF1A,LGMN,ATG4D,SEC23A,SSH3,SEC61B,RIPK2,CAPN6,PTPN9,PRKCQ,SLC11A2,PKMYT1,ASB13,XRCC6BP1,EPHA10,AMZ2,IRS2,JAK1,DDOST,CDK19,NGFRAP1,STK26,WFS1,AXL,TRIOBP,TRABD2A,NRG1,HS3ST3B1,MLKL,MAPK12,PCOLCE,NKX3-1,IGFBP6,DCAF7,SDC4,PDIA3,HERC5,CTSZ,FBXO6,PKN1,FGF19,WWP2,DTX3L,FUT2,RNF128,CTSC,ARSG,PTEN,ALG13,MGAT4A,CST3,FUT8,SGK3,BAX,ADAM15,WWP1,IGFBP2,MAPK11,ERBB3,TRIM62,NCOA2,CRTAP,ADAMTS2,RASGRF1,B3GNT2,LONRF3,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,NEURL1B,FOS,ARSK,GALNT3,RPL12,PLOD2,FGFR2,ACVRL1,DBI,PPM1H,RYK,ERAP1,GRIN2D,ITGAV,LRRK1,ARSB,WDR45B,CPEB2,ESPL1,MELK,TLL2,UNKL,CASP3,TRIM2,PPM1J,CAMKK1,CUL4B,EPHA4,LMCD1,DNAJB11,VARS2,MGAT5B,HDAC6,PDGFB,SDC1,DNER,TRIM68,SPTB,CHPF,RPS6KA2,SHC3,IMPAD1,MKRN3,PASK,DLG1,DUSP10,PTPRE,TRAM1,RASGRP1,PLK1,CD55,TRIM8,ITCH,USP18,CR2,KLK6,ROR1,PRKRA,MRPS36,TYSND1,CDK1,ADRBK2,STK17B,KDM4D,TRIM9,MAN2A2,HS6ST1,MSL1,HPSE,UEVLD,WIPI1,P4HA2,DOLPP1,CAB39,CAPN1,CPPED1,PCSK5,PRKAA2,PRSS8,LMTK3,DNAJB2,RASA2,UBASH3B,ASB9,CALM3,ADCK5,RAB6A,TEC,B4GALT4,PHLPP1,ADAMTSL4,FBLN1,B4GALNT1,OTUD1,B3GALNT1,UBE2Q2,IGF1R,TBCD,EXOC8,MDFIC,PIM1,ZRANB1,GAD1,DESI2,CKAP4,MDFI,CHSY3,MRPS33,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,G2E3,CDK5R1,GLCE,MAPKAPK2,NUDT16,UAP1,PLPP3,PHLPP2,KBTBD2,P4HA3,ZDHHC7,ALPK3,YOD1,CTSA,JAK3,APOL2,RNF146,USP43,LMO7,IL15,P3H2,PSME2,XYLT1,CTDSPL,HDAC11,PDIA5,ERBB2,KBTBD11,PHLDA1,RAD23A,PDGFA,SETDB2,ZDHHC12,KIF14,ZDHHC23,PLK4,RPN2,ECE1,NOTCH3,LMAN1,EGLN3,F2R,PDIA6,CTDSP2,SCYL3,FRS3,CTH,SEPHS1,SULF2,MAP3K3,CPD,SIRT1,PPIF,GCA,ERLEC1,AKT1,PTPRU,CDC20,PTGER4,DUSP4,CASP4,MAP3K6,DAG1,SOCS3,JADE1,DNAJC10,IDE,ATP1A1,PTPRJ,MMP17,STK38,PTK7,PEX2,ADAMTS14,SPTBN5,IRF7,ST3GAL1,LTA4H,ABCA1,NDST3,MAN2B2,CMAS,PINK1,CPEB4,TSPAN15,KLHL13,DAP,CIT,GNE,PSMD10,TGFBR1,NOTUM,TRIB2,DSE,SBF1,POMGNT1,AIP,DNAJB9,PPP2R3A,HDAC9,ZDHHC21,KIF5B,CARD8,ADRBK1,CDK16,A4GALT,RRBP1,UBE2J1,SGK1,TRIM21,BUB1,IQGAP3,SYK,MYO5A,GCNT1,B3GALT6,RAB3B,PSMB4,CFAP46,AMFR,PLAUR,RC3H2,PPARA,RGCC,RUNX3,COL7A1,GGH,PELI3,RNPEP,FOXL1,MAPK8IP1,SCRN2,PRDX4,KLHL2,FUCA1,CTSL,SERPINA1,TRIM69,SCG2,PRCP,CTSV,DTX4,OTUB2,ARRB1,SPCS3,PLOD3,CEP41,NDFIP1,UBE2C,HIPK3,ABCG1 |
| 5.531e-07 | -14.41 | Golgi apparatus part | cellular component | GO:0044431 | 870 | 132 | 17570 | 1756 |
SLC35D2,HSPG2,IL15RA,ARFGEF1,TGOLN2,MGAT5B,PJA2,PDGFB,SDC1,SLC9A7,NCS1,CHPF,AP1M2,MUC4,CABP1,STEAP2,FUT1,SCARA3,PACSIN1,MGAT5,RASGRP1,ATL1,SLC35C1,ARFRP1,KIF13A,GALNT7,MCFD2,RHEB,OPTN,MAN2A2,HS6ST1,WIPI1,GNPTAB,ATP7B,RAP1GAP,NRGN,PCSK5,PIFO,LMTK3,SCOC,HLA-E,HLA-F,RAB6A,B4GALT4,B4GALNT1,B3GALNT1,DOPEY2,TPST1,SORL1,HLA-C,PIKFYVE,NCAM1,WNT3A,MPHOSPH9,PPP6R1,KDELR1,CHSY3,B3GNT7,MGAT4B,GYLTL1B,C3orf58,GLCE,GNAS,ZDHHC7,PLD1,SLC2A4,GALNT12,ATP2C2,XYLT1,RGS20,FAM198B,EMP2,APC2,BCAP31,PDGFA,MUC16,CDH1,XYLT2,NOTCH3,RAB27B,LMAN1,CHP1,SULF2,CPD,CLCN3,SEC23A,COG2,SLC11A2,RAB38,PKMYT1,TAPBP,STK26,HS3ST3B1,ST3GAL1,NDST3,ARFGEF3,GOLIM4,SORT1,ATP9A,SDC4,CTSZ,POMGNT1,DSE,HLA-A,PARM1,ZDHHC21,FUT2,CTSC,MGAT4A,A4GALT,FUT8,FAM20B,GCNT1,B3GALT6,PDGFC,B3GNT2,SYBU,FURIN,C1GALT1C1,COL7A1,FNDC3A,GALNT3,HLA-B,NUCB1,SERPINA1,RND3,ARRB1,GPER1,FZD5,NDFIP1,GOLGB1,ABCG1 |
| 5.654e-07 | -14.39 | protein serine/threonine kinase activity | molecular function | GO:0004674 | 439 | 78 | 16491 | 1673 |
LTBP1,CAMKK1,RPS6KA1,TESK2,GRK6,CAMK1D,PRKACA,DAPK2,RPS6KA2,PASK,PIK3CA,PLK4,PHKA2,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,STK17B,CDK1,ADRBK2,STK26,CDK19,LIMK1,STK38,PLK2,MLKL,ITPKA,MAPK12,PRKAA2,LMTK3,PINK1,CDK17,NUAK1,CIT,TGFBR1,ADCK5,PKN1,BMP2K,ADRBK1,CDK16,PRKG1,MAP3K9,ADCK2,NEK2,SGK3,DAPK1,SGK1,MAPK11,BUB1,PIM1,ALPK1,MAST4,SYK,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,CDK5R1,STK17A,MAPKAPK2,PRKAG2,ACVRL1,CSNK1G1,AURKA,ALPK3,CDK18,STK39,LRRK1,MAP3K5,HIPK3,MELK |
| 5.744e-07 | -14.37 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | 191 | 42 | 17758 | 1761 |
TXN,DLGAP5,NQO1,FOXM1,PTTG1,CDCA8,CCNB1,STIL,FANCI,SAC3D1,TOP2A,BDH1,TUBG1,BUB1,LGMN,FAH,LAMP3,GCNT1,CKS2,HMMR,CENPA,ZWINT,KIF20A,ASPM,PBK,CDC20,ACO1,NUSAP1,GGH,SLC25A5,KIF11,ADRBK2,DHX32,CORO1C,AURKA,CENPE,GLA,CCNB2,UBE2C,ESPL1,ACOT7,CPPED1 |
| 5.744e-07 | -14.37 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 191 | 42 | 17758 | 1761 |
ANXA3,PACSIN2,S100A11,CD63,RPS6KA1,SAMD9,BMP2K,HLA-A,SIRPA,KIF5B,APLP2,PTEN,BCL6,IRF2,IFIT1,HLA-C,PTPRE,CDKN2D,MYO5A,XKR8,TRIM8,RAPGEF2,DOCK5,RNF19B,STK17B,KLHL2,SLC6A6,HPSE,PPP2R5A,CDK19,PRCP,KBTBD2,SECTM1,SIPA1L1,NMI,TRIOBP,ADIPOR1,EIF4EBP2,F2RL1,IFIH1,KLF7,RRAGD |
| 5.744e-07 | -14.37 | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | 191 | 42 | 17758 | 1761 |
MTM1,HECA,PACSIN2,CAST,EPHA4,TMX4,TRIB2,ETS1,DAZAP1,ACAP2,ADD3,FAM63A,CDKN1B,TMBIM6,MDFIC,TAGLN2,TIAM1,TRAM1,RASGRP1,ELK3,S100A4,BLVRA,SESN1,ALCAM,ABR,FAS,MMP15,ATP1A1,RBL1,LRIG1,INPP4B,NETO2,PGRMC1,CAB39,AGFG2,SFMBT1,FAM117A,EIF4EBP2,FHL1,REEP4,AHR,AFAP1 |
| 5.744e-07 | -14.37 | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | 191 | 42 | 17758 | 1761 |
GRN,TTC39B,ST14,PPM1J,ITGA6,SDC4,TAP1,DSE,FAM101B,FAM46C,IL18R1,FAM167A,CCND1,CDH1,FAM46A,KLF3,SGK1,IFIT1,SNX10,ALS2CL,GM2A,FAM69A,PQLC3,STAT4,CORO2A,SNTB2,SYNE2,IFIT3,ATP10D,SOCS3,ENDOD1,HLA-B,HPSE,MADD,HS3ST3B1,GEM,MAP3K5,ARSB,TRAF5,F2RL1,NXT2,XDH |
| 5.929e-07 | -14.34 | protein domain specific binding | molecular function | GO:0019904 | 614 | 101 | 16491 | 1673 |
LAMP1,NF2,THRA,INPP5D,IQGAP1,PTTG1,EPHA4,MPP5,F11R,BCL2L1,REPS1,ARHGEF16,SH3KBP1,CALM2,SCNN1A,SP100,ELMO2,SH3BP1,CABP1,KIF14,DLG1,SRR,ESPN,DAB2IP,TWIST1,DIXDC1,PDE4D,DLG3,RAB27B,DVL2,DOCK4,SIRT1,CLCN3,RIPK2,FZD4,SH3BGRL,CASP9,EZR,PRKAR2B,LDB2,DAG1,FZD7,DPYSL3,CXXC4,IRS2,ATP1A1,NKD1,NOD2,SCN5A,NKX3-1,RUNX2,PINK1,LRRFIP2,DAP,CIT,CALM3,RAB6A,HPCAL4,AIP,LBR,SIRPA,CTNNBIP1,SNTA1,CARD8,ITGA3,GATA2,LLGL2,PTEN,FUT8,BAX,ADAM15,OSTF1,WNT3A,CITED2,ATP2B1,WBP5,EPB41L5,RHOA,PLSCR1,CRB3,GUSB,FMN1,TACC1,PLAUR,RAPGEF2,CALM1,LITAF,PPARA,STMN3,SNTB1,BCAR1,TCEAL8,EPN3,CNTNAP1,TCEAL4,CABIN1,SH3BGRL2,NDE1,SHROOM2,OCLN,ARHGEF4 |
| 6.018e-07 | -14.32 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 81 | 24 | 17758 | 1761 |
PLA2G4A,SPRED1,MCTP1,CEP70,FRMD6,STAT4,SYBU,C5orf30,PBX3,IL18,FAM198B,HEATR5A,CA8,ADRBK2,MECOM,SCML1,SLC25A36,ITGB8,HOXA9,INPP4B,KLF5,SERPINI1,LIMCH1,SCN2A |
| 6.018e-07 | -14.32 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 81 | 24 | 17758 | 1761 |
SORT1,CELSR2,PRKAR2B,GDF15,GALNT7,MDK,PTPRF,EPN3,SCNN1A,MLPH,SERPINA1,TJP3,ACADSB,PLK2,WFS1,OPN3,RAB11FIP1,CADPS2,ANXA9,ERBB3,GRAMD1C,MAST4,HOOK1,ISOC1 |
| 6.066e-07 | -14.32 | HALLMARK_IL2_STAT5_SIGNALING | MSigDB lists | HALLMARK_IL2_STAT5_SIGNALING | 198 | 43 | 17758 | 1761 |
CASP3,TTC39B,CDKN1C,ITGA6,SELL,CTSZ,BCL2L1,DHRS3,PHLDA1,IL18R1,NCS1,CA2,IGF1R,COL6A1,AHCY,PIM1,ETV4,TIAM1,CKAP4,GPX4,FAH,PLSCR1,IFITM3,SLC39A8,FURIN,ALCAM,CD83,GABARAPL1,MAPKAPK2,ENPP1,NCOA3,SWAP70,TWSG1,CSF1,LRIG1,ABCB1,NFKBIZ,SH3BGRL2,SERPINB6,ITGAV,AHR,MAFF,RRAGD |
| 6.179e-07 | -14.30 | breast | COSMIC cancer mutations | breast | 17278 | 1737 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,PARM1,VPS26A,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.405e-07 | -14.26 | Lysosome | KEGG pathways | hsa04142 | 123 | 33 | 6908 | 758 |
LAMP1,GAA,SORT1,CD63,GGA1,HEXB,ASAH1,CTSZ,M6PR,GNS,ATP6V0B,AP1M2,ARSG,CTSC,GALNS,ABCA2,LGMN,NAGA,GM2A,LAMP3,LAMP2,GUSB,LITAF,SLC11A2,NPC2,FUCA1,CTSL,SCARB2,GNPTAB,CTSV,CTSA,GLA,ARSB |
| 6.405e-07 | -14.26 | Lysosome | KEGG pathways | ko04142 | 123 | 33 | 6908 | 758 |
LAMP1,GAA,SORT1,CD63,GGA1,HEXB,ASAH1,CTSZ,M6PR,GNS,ATP6V0B,AP1M2,ARSG,CTSC,GALNS,ABCA2,LGMN,NAGA,GM2A,LAMP3,LAMP2,GUSB,LITAF,SLC11A2,NPC2,FUCA1,CTSL,SCARB2,GNPTAB,CTSV,CTSA,GLA,ARSB |
| 6.416e-07 | -14.26 | positive regulation of signal transduction | biological process | GO:0009967 | 1418 | 200 | 16441 | 1675 |
TXN,LGR4,EPHA4,RET,ARFGEF1,LMCD1,NRG2,PSME1,IL18,NENF,HDAC6,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,SIVA1,TSPAN6,IL31RA,AKR1B1,SLC39A10,S100A13,RASGRP1,CYP1B1,TRIM8,SH3BGRL,KLK6,PRKRA,CDK1,POR,RHEB,PLCG1,GPRC5B,HPSE,AGPAT2,DNM1L,ANKRD6,PLK2,MADD,NKD1,FAM110C,NOD2,PRKCDBP,ADIPOR1,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,RRAGD,LASP1,BMF,CDKN1C,RASA2,SOX9,CALM3,TNFRSF19,IL18R1,KIAA1161,TFAP4,IGF1R,CYR61,PIK3AP1,KCNN4,MAP3K9,MDFIC,TNFRSF12A,MYDGF,C10orf54,NCAM1,ZRANB1,WNT3A,MDFI,KLK5,CALM1,AMER1,PDE5A,PSMA4,RASA1,FAS,GNAS,MAPKAPK2,SEMA4D,PELI2,CSF1,NLRC5,GDF11,MAP3K5,JAK3,TOB1,RNF146,RUSC1,XDH,SPRED1,SORBS1,AVPI1,IL15,PSME2,TP53,ERBB2,BCL2L1,EMP2,BCAP31,PDGFA,NOV,ST5,RNF220,DACT1,CDH3,DAB2IP,DIXDC1,RASGEF1A,F2R,NR2C1,DVL2,FRS3,SULF2,CTH,MAP3K3,SIRT1,PPIF,TIMP2,RIPK2,AKT1,FZD4,S100A4,PRKCQ,CD40,MAP3K6,FZD7,IRS2,PTPRJ,JAK1,AXL,SECTM1,NRG1,IRF7,SPTBN5,PINK1,NKX3-1,ADGRG1,CD63,TSPAN15,EPS8,PDIA3,PSMD10,TGFBR1,GDF15,PKN1,FGF19,PPP2R3A,NEO1,ADORA1,CTSC,PTEN,BMP7,BAX,PLEKHF1,SLC44A2,BUB1,MAPK11,ERBB3,CITED2,IQGAP3,SYK,SPRY2,TRIM62,RASGRF1,HES1,RHOA,PSMB4,ASPM,RAPGEF2,PLAUR,PIK3R1,RC3H2,GRIN1,LITAF,FURIN,MAPK8IP1,CNTNAP1,BANK1,FGFR2,ACVRL1,TWSG1,RYK,ARRB1,GRIN2D,GPER1,LRRK1,FZD5,NDFIP1,L1CAM |
| 6.429e-07 | -14.26 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | 488 | 83 | 17758 | 1761 |
LTBP1,NCKAP5,KLK10,HDAC11,PTTG1,TP53,FAM102B,SLC7A2,OSR2,SYTL4,EMP2,BARD1,ZNF385B,SYTL2,UBE2T,METTL7A,PAPSS1,ATRNL1,CDH3,TMEM64,MYBL1,SNX10,TIAM1,SULT2B1,SEMA3B,LAMP2,CELSR2,RIPK2,PTGER4,TFAP2C,NUSAP1,COL12A1,TMEM164,ZNF114,MID1IP1,JAK1,INPP4B,DHTKD1,HSPB1,ISOC1,CD99,GOLIM4,LRRFIP2,NUAK1,ZCCHC24,FRMD6,PYROXD2,GTF3A,COL4A5,NTAN1,PPP2R3A,DAZAP1,CA2,IGF1R,SLC27A6,RALGPS2,PTEN,LYPD6,FUT8,SGK3,ECI2,WWP1,MDFIC,IQGAP3,RIMS2,MYO5A,HMMR,KIF20A,PRSS23,ASPM,SYBU,STMN3,NFIB,CRISPLD2,MAPKAPK2,ARHGAP24,FGFR2,TCEAL4,FHL1,CCNB2,UBE2C,L1CAM,JARID2 |
| 6.659e-07 | -14.22 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | 192 | 42 | 17758 | 1761 |
ARHGAP11A,MTM1,SPC25,DEPDC1,FOXM1,CKAP2,CENPI,KIF23,NUF2,STIL,CENPN,TOP2A,APLP2,E2F7,PASK,NEK2,BUB1,HMMR,PLK1,CENPA,KIF20A,ASPM,PBK,MYBL2,EZR,CDCA2,PIF1,ANLN,CCNF,CDK1,PRIM1,FAM64A,CDCA7L,CDCA5,FAM114A1,AURKA,CENPE,NCAPG2,UBE2C,CCNB2,E2F8,MELK |
| 6.668e-07 | -14.22 | regulation of cell adhesion | biological process | GO:0030155 | 613 | 101 | 16441 | 1675 |
LMO7,CASP3,NF2,IL15,RET,ERBB2,IL18,CD274,EMP2,TNFSF9,EPCAM,CDH1,NPNT,IL6ST,KIF14,BCL6,PIK3CA,DLG1,TACSTD2,EPB41L4B,RASGRP1,CYP1B1,CD55,CELSR2,RIPK2,AKT1,FZD4,ITCH,UTRN,ARHGDIB,PRKCQ,FZD7,PTPRJ,CORO1C,TRIOBP,NOD2,EFNA5,SERPINI1,NRG1,PIEZO1,RAP1GAP,LGALS3,SERPINE2,ADGRG1,NUAK1,ITGA6,UBASH3B,HLA-E,SOX9,SDC4,FAM21C,FBLN1,EFNB1,HLA-A,ITGA3,CYR61,PTEN,BMP7,TBCD,PRKG1,ADAM15,FXYD5,IGFBP2,C10orf54,ERBB3,CITED2,WNT3A,SYK,SOCS5,EPB41L5,HES1,RHOA,MFI2,FMN1,PIK3R1,PPARA,RGCC,PDE5A,EPHA1,YES1,RASA1,STX3,SOX13,CD83,ONECUT1,AP1AR,SWAP70,SEMA4D,ACVRL1,PLPP3,CSF1,SPINT2,TBX18,NR4A3,ITGAV,ARPC2,ICOSLG,NDFIP1,JAK3,COL16A1,L1CAM |
| 6.753e-07 | -14.21 | kinase regulator activity | molecular function | GO:0019207 | 150 | 36 | 16491 | 1673 |
CCNE2,CASP3,SPRED1,NKX3-1,CDKN1C,IQGAP1,DNAJC3,CALM3,TRIB2,GSTP1,CALM2,CDKN2C,CCND1,PIK3CA,CDKN1B,ERBB3,CDKN2D,SPRY2,CKS2,CHP1,CALM1,PIK3R1,RGCC,PRKAR2B,MAPK8IP1,CDK5R1,SOCS3,CDK5RAP1,PRKAG2,GPRC5B,MADD,CAB39,NRG1,EFNA5,HSPB1,PKIA |
| 6.761e-07 | -14.21 | cell projection | cellular component | GO:0042995 | 1731 | 233 | 17570 | 1756 |
LAMP1,SSH1,EPHA4,RET,FBXO2,NDRG2,LYNX1,HDAC6,DNER,TMC1,GRM5,NCS1,SH3KBP1,PLS3,CALM2,RAB15,ANKS6,LRRC6,IQCE,IL6ST,CABP1,DPYSL2,PIK3CA,DLG1,AKR1B1,TUBG1,RP2,MYH14,CTTN,TLN2,PACSIN1,MYRIP,ATL1,ORAI2,SPEF2,SGCE,SPATA18,EZR,PRKAR2B,ARF4,ARHGEF26,DZIP1L,DPYSL3,PIAS3,MDK,TRIM9,PLCG1,MAP2,KCNK1,PLK2,LIMK1,TRAF3IP1,TMOD2,PIEZO1,ITPKA,ARF6,NRGN,F2RL1,LZTS1,FGD1,DDX58,PIFO,ARAP3,LMTK3,BVES,CALB2,CALM3,NCKAP1,SLC1A3,CNTNAP2,MERTK,DHRS3,ITGA3,CA2,IGF1R,SNX18,RINL,KIF13B,FLRT3,EXOC8,AHCY,TNFRSF12A,CCDC88A,GPR161,EPB41L5,DPYSL5,CALM1,SPATA13,SCRIB,ELK1,NPHP3,ANTXR1,NUBP1,GNA11,NFIB,STX3,RASA1,CDK5R1,FRMD4B,FAS,RASGRP2,GNAS,PTPRF,GABRD,PLEKHH2,PHLPP2,FGD6,AURKA,ARPC2,CFAP20,SEMA3A,NRBP1,EHD1,PROM2,TPRN,MTM1,DYNLRB1,NF2,TCTN2,TRIP10,S100A11,IQGAP1,C5orf30,ERBB2,PRKACA,APC2,MNS1,EPS8L2,TTC21B,PDGFA,NOV,SCNN1A,CDH1,DAB2IP,GOT1,ESPN,SCN2A,DLG3,SCYL3,DOCK4,CLCN3,TIMP2,MBP,AKT1,S100A4,SEPT6,SYNE2,CCSAP,CYS1,UTRN,SLC11A2,ALCAM,DAG1,CFAP36,GABARAPL1,CEP162,ATP1A1,PTPRJ,SLC9A6,CORO1C,WFS1,SIPA1L1,NRG1,SPTBN5,RGS14,COBL,TTC8,BIN1,WASF3,ANXA3,PINK1,SORT1,PACSIN2,CPEB4,ADGRG1,CIT,POC1B,EPS8,LRP4,ARL4C,GABRG2,DNAH3,KIF5B,ADD3,ADORA1,ADRBK1,IGSF9,MLPH,GNB5,PTEN,CDK16,ANKS1B,CST3,CFAP43,KLC3,ATP8B1,ADAM15,SPRY2,S100A6,MYO5A,DLGAP1,RASGRF1,ZWINT,RHOA,LCA5,CFAP46,MPP1,RAPGEF2,PLAUR,GRIN1,STMN3,AIF1L,FOS,BCAR1,BBS2,MAPK8IP1,CNTNAP1,KLHL2,ARHGAP24,SWAP70,SYT7,CTSV,ARRB1,GRIN2D,ITGAV,GPER1,CEP41,CPEB2,L1CAM,ACOT7,CYBRD1,ARHGEF4,SNPH |
| 7.007e-07 | -14.17 | endoplasmic reticulum part | cellular component | GO:0044432 | 1114 | 161 | 17570 | 1756 |
IL15RA,DNAJC3,TAP1,DNAJB11,ITPR2,PJA2,PDGFB,ERP29,ABCD4,CYP1A1,STIM1,OSBPL3,CYP2S1,DLG1,MARCH2,TECR,SCARA3,TRAM1,RASGRP1,ERAP2,CYP1B1,ATL1,NFE2L1,ICMT,MCFD2,PTGFRN,CYP4F3,POR,RHEB,COL12A1,AGPAT2,P4HA2,DOLPP1,SARAF,PIEZO1,FXYD3,HLA-E,HLA-F,ADAMTSL4,DHRS3,FLRT3,COL6A1,SUCO,SELK,HLA-C,MYDGF,FAR2,WNT3A,ALDH3A2,CKAP4,KDELR1,FAM69A,CYP26B1,FADS2,LPGAT1,ERO1A,EMC2,SPTLC2,CYB5A,FAAH,COL13A1,PLPP3,MFSD2A,P4HA3,ITPR1,PLD1,MAP3K5,COL16A1,APOL2,TMEM173,PLA2G4A,P3H2,XYLT1,PDIA5,COL18A1,MGST2,LPIN3,CYP39A1,BCAP31,CYP26A1,CDS1,RCN1,PDGFA,CYP4F11,XYLT2,REEP1,RPN2,ACSL4,NOTCH3,LMAN1,MINPP1,PDIA6,MX1,SEC23A,SEC61B,COL6A2,EVA1A,ERLEC1,C3orf52,SYNE2,DNAJB14,PKMYT1,ITPR3,TRIQK,CASP4,ATP10D,TAPBP,DNAJC10,DDOST,SLC9A6,WFS1,PNPLA6,CYP2U1,REEP4,NR3C2,COL9A3,SORT1,PDIA3,COL4A5,CTSZ,FBXO6,LBR,DNAJB9,HLA-A,SGPL1,PDIA4,CTSC,ARSG,ALG13,RRBP1,UBE2J1,BAX,SGK1,TMBIM6,CNPY3,CRTAP,PDGFC,RHOA,PLAUR,AMFR,ELOVL3,EIF5A2,PIK3R1,FURIN,COL7A1,ARSK,TXNDC11,MAPK8IP1,HLA-B,SERPINA1,PLOD2,DBI,PGRMC1,ERAP1,SPCS3,GPER1,PLOD3,ARSB,PTGES,ESYT2,ABCG1 |
| 7.231e-07 | -14.14 | human chrXq22.3 | chromosome location | human chrXq22.3 | 26 | 11 | 26250 | 1887 |
TMEM164,RNF128,TBC1D8B,TSC22D3,AMMECR1,CXorf57,MORC4,PSMD10,NUP62CL,MUM1L1,ATG4A |
| 7.288e-07 | -14.13 | GSE3982_BCELL_VS_TH2_DN | MSigDB lists | GSE3982_BCELL_VS_TH2_DN | 186 | 41 | 17758 | 1761 |
ARHGAP11A,MRC2,SPC25,DLGAP5,EPAS1,FOXM1,VANGL1,ATP9A,CIT,CENPI,ATP2C2,PTTG1,HES2,HOXB2,NCS1,ZFYVE9,RCN1,BTG3,CYP1A1,BDH1,DAPK1,MAPK11,DIXDC1,ALDH3A2,CKS2,PLK1,HMMR,MPP1,YES1,RAB38,EDNRA,FECH,GABRD,FAM64A,BMP1,INPP4B,GEM,TBC1D4,LIFR,AFAP1,ACOT7 |
| 7.448e-07 | -14.11 | multicellular organismal process | biological process | GO:0032501 | 6447 | 749 | 16441 | 1675 |
HECA,ADD1,AK7,HEXB,RET,NRG2,IL18,BARD1,LTBP3,GRM5,CALM2,CDKN2C,WEE1,PSMD1,MUC4,PAQR5,ALDH1A3,KLF3,CLDN4,CRY2,SEMA3G,PIK3CD,TIAM1,TIPARP,ERAP2,SPEF2,SMARCA2,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,COL12A1,ABR,PGF,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,ITPKA,ARF6,HSPB1,E2F8,GAB1,HOXC13,SCN5A,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,RABGGTA,ELF3,FRY,MEGF8,FLRT3,NEK2,MYDGF,NCAM1,DGKG,MYLIP,NDUFA12,PAQR7,REC8,SALL4,NPHP3,TP53INP2,GNA11,PSMA4,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,ITPR1,AURKA,CLMN,STK39,GDF11,NDE1,DRP2,ARPC2,CFAP20,TMEM173,XDH,ADAMTS16,EGLN1,DOCK9,TPRN,GRHL2,PAPSS2,INPP5D,PTTG1,PKP2,TESK2,PRKACA,APC2,TNFSF9,CCND1,RCN1,SCNN1A,CDH1,DACT1,RTKN2,ACSL4,LRP11,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,SNX10,SCN3A,ENPP4,CAMSAP3,SSH3,COL6A2,FZD4,SAT1,HTATIP2,NFIX,IRS2,PDLIM3,SHROOM3,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,PNPLA6,RGS14,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,DCAF7,SDC4,HABP4,BTN3A1,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,SRPX2,HOXB2,SGPL1,NEO1,CTNNBIP1,ITGB8,IGSF9,CALD1,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,SGCB,S100A6,CRTAP,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,GRIN1,UBE2A,AK4,SNTB1,CRISPLD2,CNTNAP1,PITX2,RAB11FIP2,ACVRL1,DBI,NR4A3,ITGAV,CENPE,FHL1,OSR1,USF2,TLL2,MYL9,CCNI,EPAS1,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,ITPR2,PDGFB,SDC1,SPTB,PLS3,RPS6KA2,NPNT,SHC3,IL6ST,PAPSS1,MITF,ELF5,TMEM143,DUSP10,NTN4,NEB,S100A13,THRB,CD55,KCNIP3,CELSR2,NFE2L1,CR2,EZR,KLK6,ARFRP1,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,HS6ST1,KCNMB4,MAP2,HOXA9,PRKCDBP,MYL12B,MAFF,RUNX2,LGALS3,RASA2,PDCL,NCKAP1,CNTNAP2,FBLN1,DHRS3,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,SPIN4,GATA2,FRAS1,KIF13B,PIM1,WNT3A,PLCB2,ALDH3A2,CYP26B1,DPYSL5,PCDH1,TESK1,RGMB,SCRIB,EIF2AK1,TCF7,G2E3,PRX,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,COL13A1,PHLPP2,ITGA7,CSF1,PRPS2,ATP1B3,CCNB2,SEMA3A,NF2,HOXB7,FOXM1,P3H2,TP53,ERBB2,SLC7A2,STIL,EMP2,BCAP31,IER3,TTC21B,PDGFA,LMO4,PLCG2,LHX6,SRR,BCL6,PLK4,CDH3,ESPN,NOTCH3,SCN2A,MINPP1,LMAN1,GM2A,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CCSAP,CDC20,PTGER4,ACO1,MYL12A,DAG1,DUOX1,PTPRJ,ATP1A1,IDE,ABHD12,PTK7,ADAMTS14,EFNA5,IRF7,LTA4H,BIN1,COL9A3,CDH22,CD63,ADGRG1,GABRG2,SELL,PSMD10,CRABP2,FZD6,PPP2R3A,NRP2,SIRPA,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,UBE2J1,SGK1,ALDH7A1,SYK,ATP2B1,TLE6,GCNT1,HES1,RHOA,PSMB4,PLAUR,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BCAR1,BBS2,RNPEP,DGKE,PRDX4,SERPINA1,FAT4,TWSG1,SCG2,PGRMC1,PPP2R3C,GAA,SSH1,LGR4,HSPG2,VANGL1,TMEM41B,ATP8A1,PSME1,CAMK1D,PLXNA1,CCNB1,PJA2,OAT,VASH1,FAM101B,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,FOSB,PIK3CA,IRF2,TACSTD2,PACSIN1,ZBTB18,LAMP2,SGCE,ACVR1C,CASP9,CCNF,SAV1,LDB2,ZFAND5,HLF,PLK2,NKD1,LRIG1,BMP1,DHTKD1,EIF4EBP2,SERPINI1,UNC5B,TANC2,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,CDKN1C,DGKQ,SLC25A27,KIF23,SLC1A3,HERC6,TNFRSF19,S100A2,KIAA1161,MECOM,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,SORL1,TNFRSF12A,OSTF1,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,EPB41L5,GFPT1,KCNJ12,MMD,CALM1,AMER1,ANO6,VEZT,EPHA1,NFIB,RASA1,STX3,FAS,DGKH,MMP15,GABRD,MATN2,FAM83D,SFMBT1,PCDH19,NR4A2,PER3,HOOK1,EHD1,PLA2G4A,SPRED1,FOXO6,ST14,THRA,RPS6KA1,IQGAP1,CAST,BCL2L1,DDR1,CYP39A1,MNS1,APLP2,NOV,DOK4,CNNM4,CDKN1B,DAB2IP,PDE4D,EPHB4,LGMN,MED30,GPX4,SEMA3B,MYO5B,UTRN,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,JAK1,NGFRAP1,KLF5,NRG1,PRR15,COBL,CBX7,WASF3,PCOLCE,HAPLN3,CENPI,EPS8,PBX3,SEPP1,SPR,EFNB1,FGF19,TEAD3,ADGRB2,SIX4,SNTA1,E2F7,PTEN,FUT8,FJX1,CD9,ATP8B1,ERBB3,CITED2,SPRY2,OSGIN1,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,B3GNT2,ARHGEF28,FURIN,DIAPH2,C1GALT1C1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,NCAPG2,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,CRYM,MPP5,CACNB4,DNER,TMC1,HTR1D,EPCAM,HSF2,LRRC6,GRHL1,IMPAD1,DPYSL2,DLG1,AKR1B1,TRPC1,RP2,MYH14,CTTN,BTBD3,RASGRP1,SP5,CYP1B1,ATL1,TRIM8,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,NRGN,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,CA2,KCNN4,COL6A1,SUCO,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,OXR1,BTN3A2,VWA1,HMG20B,PDE5A,C3orf58,RANBP9,FECH,GNAS,BCAR3,ONECUT1,PLPP3,UTP14C,TMEM30A,ALPK3,EGFL7,DONSON,PITPNA,SHROOM2,JAK3,RARG,COL16A1,APOL2,KLF7,DYNLRB1,SORBS1,IL15,PSME2,HDAC11,COL18A1,TDRKH,MRAS,OSR2,PHLDA1,SS18,ARTN,SETDB2,CYP4F11,FRYL,KIF14,TWIST1,DIXDC1,ECE1,F2R,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,DUSP4,CD40,ARHGAP35,SOCS3,ALDH5A1,BFSP1,BHLHB9,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,LIFR,ABCA1,ANXA3,GCLM,SORT1,ARHGEF11,POC1B,CIT,LRP4,TGFBR1,AES,COL4A5,SBF1,NTAN1,HDAC9,KIF5B,TOP2A,MDM1,ADORA1,ADRBK1,LLGL2,BMP7,MYCL,RRBP1,TOX2,KIAA0319,ARVCF,MYO5A,ASPM,NR4A1,GCLC,RC3H2,RGCC,MBNL3,TTC7A,RUNX3,LEPR,FOXL1,CTSL,ARHGAP24,SWAP70,DHRS2,PRCP,CTSV,SPINT2,ARRB1,HOXB13,PLOD3,ZMIZ1,SOX8,L1CAM,AHR,ABCG1 |
| 7.497e-07 | -14.10 | regulation of cell migration | biological process | GO:0030334 | 630 | 103 | 16441 | 1675 |
NF2,ATP8A1,RET,COL18A1,PKP2,PLXNA1,CD274,CAMK1D,VASH1,HDAC6,PDGFB,EMP2,PDGFA,DAPK2,NOV,SVBP,SP100,KIF14,DAB2IP,TACSTD2,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,CYP1B1,SEMA3B,DOCK4,AKT1,ACVR1C,PTPRU,SYNE2,PTGER4,ARHGDIB,DOCK5,DAG1,ABR,DPYSL3,IRS2,PLCG1,PTPRJ,CORO1C,FAM110C,NOD2,NRG1,HSPB1,F2RL1,GAB1,DDX58,SEMA6B,ANXA3,TCAF1,ARAP3,LGALS3,SERPINE2,ADGRG1,SOX9,SDC4,SELL,ETS1,FBLN1,SRPX2,NRP2,LMNA,HDAC9,CXCL16,ITGA3,ADORA1,IGF1R,CYR61,PTEN,SGK3,SGK1,ADAM15,SORL1,CITED2,EPB41L5,SUN2,RHOA,MPP1,RAPGEF2,PIK3R1,ANO6,FURIN,RGCC,SPATA13,EPHA1,BCAR1,GPLD1,ONECUT1,SWAP70,SEMA4D,ACVRL1,PLPP3,PRCP,CSF1,RAP2C,EGFL7,ITGAV,GPER1,PLD1,ARSB,SEMA3A |
| 7.708e-07 | -14.08 | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | 193 | 42 | 17758 | 1761 |
DDX58,PARP12,IL15RA,IL15,PSME2,TAP1,HERC5,SAMD9,FBXO6,HERC6,LGALS3BP,DTX3L,TYMP,SP100,PIK3AP1,IFIT1,OAS3,LAMP3,PARP9,HMMR,REC8,MX1,ZWINT,PLSCR1,IFITM3,USP18,UTRN,C1GALT1C1,BLVRA,IFIT3,SPTLC2,PSMA4,SCARB2,TRIM69,C19orf66,AXL,NMI,SECTM1,IRF7,CMPK2,IFIH1,IFI6 |
| 7.852e-07 | -14.06 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 377 | 68 | 17758 | 1761 |
MYL9,NQO1,BROX,CTDSPL,TAP1,RGS20,ARFGEF1,MRAS,LACTB2,FAM101B,CENPN,LMO4,LHX6,AKR1B1,RASGEF1A,PLK1,ATL1,DRAP1,SERTAD4,PLEKHO1,PRKAR2B,ROR1,CD40,ALCAM,FZD7,CXXC4,TRAF3IP1,ZNF704,TRAF5,NR3C2,CBX7,LNP1,CHCHD7,FRMD6,CALB2,CTSZ,ETS1,DHRS3,PDIA4,CCDC92,TNS3,PHF7,GATA2,CALD1,GALNS,NEK2,FAM102A,ABCD1,CD70,PANX2,TAGLN2,RFX5,ATP2B1,OSGIN1,FARP2,C9orf9,SYPL1,HES1,PSMB4,DIAPH2,ATP8B3,AIF1L,SLCO4A1,NFKBIA,SH3BP4,ARRB1,EGFL7,ICOSLG |
| 8.641e-07 | -13.96 | RIGGI_EWING_SARCOMA_PROGENITOR_DN | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_DN | 174 | 39 | 17758 | 1761 |
AVPI1,RUNX2,DLGAP5,ZNF395,DEPDC1,IGFBP6,GALNT12,CUL4B,GPSM2,DHRS3,TNFRSF19,FBLN1,PHLDA1,CARD10,NRP2,TOP2A,RPS6KA2,ALDH1A3,AIM1,SCARA3,FAR2,RAB27B,COL6A2,MFI2,ASPM,PBK,NUSAP1,DUSP4,ANLN,ITPR3,GLT8D2,DPYSL3,NR1D2,TRIOBP,FAM83D,TANC2,OSR1,GLCCI1,F2RL1 |
| 8.834e-07 | -13.94 | Ras guanyl-nucleotide exchange factor activity | molecular function | GO:0005088 | 127 | 32 | 16491 | 1673 |
ARHGEF3,ARHGEF11,SBF1,ARHGEF40,DENND2D,ARHGEF16,EPS8L2,ARHGEF10L,ST5,ARHGEF37,RASGEF1A,TIAM1,ALS2CL,RASGRP1,FARP2,RASGRF1,ARHGEF28,RAPGEF2,SPATA13,ABR,ARHGEF26,PLEKHG6,ARHGEF19,MADD,PLEKHG1,FGD6,ARHGEF9,RAB3IL1,FGD1,ARHGEF4,DOCK9,DENND5B |
| 8.910e-07 | -13.93 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | 194 | 42 | 17758 | 1761 |
LMO7,PEX6,ATP8A1,HDAC11,CACNA2D2,NDRG2,TGFBR1,ITPR2,MGST2,ARHGEF10L,CDKN2C,LLGL2,PHTF1,KLC3,DAPK1,DUSP10,CLDN4,RAB20,ALDH7A1,ERBB3,NOTCH3,RCAN3,DLG3,SYTL3,ATG4D,REC8,RASGRF1,MBP,PQLC3,NR3C1,MPP1,SYNE2,EZR,ATP1B1,C3orf58,DGKE,CYB5A,LRRC42,PGF,NR4A3,SH3BGRL2,TMEM131 |
| 8.910e-07 | -13.93 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | 194 | 42 | 17758 | 1761 |
CCDC109B,PARP12,NFKBIE,IL15RA,IL15,PSME2,HLA-E,TAP1,HERC6,PRRG4,RAD23A,CDS1,RCN1,TYMP,AIM1,LRIF1,ETV7,ERAP2,MX1,ARAP2,PLSCR1,RAPGEF2,SNTB2,PLEKHO1,C15orf39,CD40,PSMA4,CASP4,BCAR3,LRRC42,NCOA3,STK38,SECTM1,PRPS2,NMI,NOD2,GRIN2D,IRF7,IFIH1,APOL2,ISOC1,MELK |
| 8.959e-07 | -13.93 | GATTGGY_V$NFY_Q6_01 | MSigDB lists | GATTGGY_V$NFY_Q6_01 | 1110 | 159 | 17758 | 1761 |
EXPH5,LTBP1,DNAJB11,NANS,ITPR2,OAT,NUP62CL,SPTB,WEE1,SESN3,SHC3,STIM1,DPYSL2,RGS3,OSBPL3,FOSB,PASK,STEAP2,TMEM143,AKR1B1,ANKRD12,DUSP10,IQCD,RP2,MYH14,TECR,ANO4,RNF26,BTBD3,TIAM1,NEB,LAMP2,PLK1,CR2,LDB2,CDK1,TYSND1,KDM4D,DOLPP1,PRDM5,AGFG2,HDAC1,EIF4EBP2,GLA,NRGN,E2F8,NR2C2,RMND5A,ALDH6A1,HLA-F,SOX9,ETV5,SLC25A27,ASB9,KIF23,RAB6A,C3orf18,RFX5,NCAM1,RIMS2,CYP26B1,DPYSL5,REC8,MMD,KIF20A,HMG20B,SPTLC2,TP53INP2,RANBP9,SFXN5,FAM64A,AURKA,CDK18,NDE1,PER3,PLIN3,IFI6,PROM2,DOCK9,ARHGAP11A,AVPI1,SPC25,CEP70,TCTN2,GRHL2,NF2,CAST,TESK2,TDRKH,FTH1,BCL2L1,PRKACA,CYP39A1,ZNF385B,CDH1,LMO4,CDH3,RPN2,GOT1,TWIST1,DLG3,EGLN3,ETV4,CKS2,MAP3K3,GCA,C6orf1,COQ10B,SERTAD3,SLC11A2,ATP1B1,CD40,ATP10D,PPP2R5A,DDOST,PEX2,TLE1,EFNA5,IER5L,SORT1,NKX3-1,TNRC6C,CPEB4,CIT,PBX3,PDIA3,CRABP2,HOXB2,M6PR,TOP2A,KIF5B,CDK16,LLGL2,FUT8,TSPAN13,BUB1,KLF9,C12orf75,TPCN1,TGIF1,RHOA,BCL9,PIK3R1,BORA,PITX2,FUCA1,FGFR2,PRCP,HNRNPH2,DBI,UACA,FAM117A,HOXB13,HMGA1,CEP41,UBE2C,ESPL1,JARID2,TLL2 |
| 8.998e-07 | -13.92 | TANG_SENESCENCE_TP53_TARGETS_DN | MSigDB lists | TANG_SENESCENCE_TP53_TARGETS_DN | 56 | 19 | 17758 | 1761 |
CENPA,KIF20A,PBK,CDC20,PTTG1,KIF23,NUSAP1,KIF11,BARD1,CDK1,TOP2A,PLK4,NEK2,BUB1,CENPE,UBE2C,NRGN,CCNB2,CTH |
| 9.029e-07 | -13.92 | MODULE_33 | MSigDB lists | MODULE_33 | 371 | 67 | 17758 | 1761 |
MYL9,LTBP1,UGT8,NF2,HSPG2,HOXB7,EPAS1,CRYM,THRA,EPHA4,ERBB2,TP53I11,SLC20A1,SCNN1A,RPS6KA2,RGS3,BCL6,IFIT1,LGMN,NEB,CPD,MX1,CR2,KLK6,DUSP4,NFIX,MAN2A2,PTK7,SECTM1,TLE1,NRG1,MAPK12,PRSS8,NKX3-1,PCOLCE,IGFBP6,ITGA6,DCAF7,HAL,ASAH1,SELL,GDF15,TRIB2,MERTK,ETS1,SEPP1,TSPAN7,LGALS3BP,ELF3,GATA2,RIMS3,CALD1,COL6A1,CD9,MAPK11,CD70,GCNT1,SHMT1,MMD,TESK1,FURIN,SPTLC2,CNTNAP1,FAAH,PLOD2,DRP2,JAK3 |
| 9.031e-07 | -13.92 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 691 | 108 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,NDRG2,GRK6,CAMK1D,DPP8,PRKACA,DDR1,ABCD4,DAPK2,WEE1,CYP1A1,RPS6KA2,CDH1,PAPSS1,PIK3CA,PLK4,EPHB4,SCYL3,MYO5B,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,UTRN,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,SOCS3,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,LIFR,MAPK12,GRN,PRKAA2,PINK1,BMF,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,TFAP2A,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SLC12A2,SYK,PGM1,PLEKHA6,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,STK17A,GNAS,MAPKAPK2,FAT4,ACVRL1,FGFR2,PHLPP2,SLC4A3,ALPK3,AURKA,CDK18,MAP3K5,ARPC2,JAK3,HIPK3,NRBP1,MELK |
| 9.169e-07 | -13.90 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 673 | 106 | 17758 | 1761 |
ARHGAP11A,HOXB7,S100A11,FOXM1,CAST,IQGAP1,CUL4B,NDC80,NUF2,MORF4L2,BCL2L1,CCNB1,STIL,TNFSF9,SYTL2,IER3,ACAP2,SP100,KIF14,DLG1,PIK3CA,PLK4,HYLS1,RAB27B,LMAN1,MYBL1,CKS2,CENPA,FIGNL1,ITCH,CDC20,NUSAP1,ROR1,ANLN,STK17B,CDK1,CASP4,ANKRD10,DNAJC10,DNM1L,PLK2,ZNF367,CORO1C,STK38,EFNA5,DDX58,CTHRC1,RUNX2,DEPDC1,CKAP2,ETV5,ARL4C,GDF15,TGFBR1,SAMD9,DSE,S100A2,SIX4,HDAC9,KIF5B,TOP2A,E2F7,ADORA1,RALGPS2,TOX2,TFAP2A,NEK2,TNFRSF12A,LRIF1,ULBP2,GAD1,ATP2B1,CCDC88A,HMMR,GFPT1,NFE2L3,HPS3,PLSCR1,ASPM,MICB,OXR1,RC3H2,AK4,COL7A1,IFIT3,BORA,KIF11,G2E3,FAS,STK17A,SLCO4A1,RND3,TMEM30A,AMMECR1,NMI,AURKA,PPP2R3C,CTSA,CENPE,UBE2C,IFIH1,SEMA3A,L1CAM,MELK,ESYT2,TLL2 |
| 9.223e-07 | -13.90 | pancreas | COSMIC cancer mutations | pancreas | 17360 | 1742 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,PPP4R1,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 9.243e-07 | -13.89 | PRC2_EZH2_UP.V1_DN | MSigDB lists | PRC2_EZH2_UP.V1_DN | 181 | 40 | 17758 | 1761 |
SLC35D2,IL15RA,ARL4C,CCDC68,KCTD12,COL4A5,SRPX2,TSPAN7,SCML1,B4GALNT1,PDGFA,PAQR5,ALDH1A3,OPN3,CD70,TSPAN13,ETV4,OSGIN1,ERAP2,FAM69A,ORAI2,MCTP1,OSTM1,PCBP3,C3orf52,PCTP,POPDC3,COL13A1,AMMECR1,TRAF3IP1,OTUB2,YOD1,KLK7,KLF11,NR4A2,F2RL1,SEMA3A,L1CAM,NR3C2,PKIA |
| 9.243e-07 | -13.89 | GSE25087_TREG_VS_TCONV_FETUS_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_FETUS_UP | 181 | 40 | 17758 | 1761 |
GOLIM4,ARAP3,LGALS3,EPAS1,FRMD6,LRP4,ERI2,DHRS3,FAM46C,CMTM6,PLS3,APLP2,CYP1A1,PIK3AP1,DPYSL2,TOX2,PPP4R1,TWIST1,KLF9,PIM1,CTTN,DLG3,SNX10,MMD,BTNL9,AMFR,ATP1B1,DOCK5,PCTP,KLHL2,IRS2,HLF,RAB11FIP1,NETO2,PGM2L1,KLF11,HS3ST3B1,ATP1B3,GLCCI1,AHR |
| 9.243e-07 | -13.89 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | 181 | 40 | 17758 | 1761 |
DDX58,TXN,IL15,CD274,MORF4L2,HERC6,CMTM6,BTG3,SESN3,ITGB8,GRHL1,FJX1,CD70,SELK,IFIT1,ARAP2,RIPK2,TNIP1,USP18,STAT4,RAPGEF2,LYRM1,SAT1,NUB1,PTGER4,AK4,DUSP4,SOCS3,OPTN,GALNT3,SWAP70,UAP1,SERPINA1,TRIM69,MFSD2A,NETO2,IRF7,CMPK2,IFIH1,SERPINB1 |
| 9.265e-07 | -13.89 | negative regulation of protein metabolic process | biological process | GO:0051248 | 1025 | 152 | 16441 | 1675 |
SIGIRR,CASP3,PPP4R4,DNAJC3,NDRG2,PSME1,CCNB1,HDAC6,CALM2,CDKN2C,PSMD1,ZFP36,RGS3,DLG1,DUSP10,CRY2,PLK1,CD55,TNIP1,ITCH,PBK,EZR,AGO4,PRKAR2B,POR,PIAS3,ENPP1,LIMK1,TRAF3IP1,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,LMTK3,CDKN1C,SERPINE2,DNAJB2,UBASH3B,PDCL,RAB23,CALM3,FBLN1,MECOM,TFAP4,IGF1R,PAIP2B,DAPK1,SORL1,SOCS5,CALM1,HMG20B,EIF2AK1,EPHA1,PSMA4,RANBP9,FAS,PRKAG2,SEMA4D,PLPP3,STK39,YOD1,SERPINB1,JAK3,TOB1,IFI6,XDH,SPRED1,NF2,FOXM1,INPP5D,RPS6KA1,PSME2,CAST,PTTG1,CTDSPL,TP53,SYTL2,APLP2,SVBP,DACT1,CDKN1B,DAB2IP,TWIST1,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,CAMSAP3,ERLEC1,TIMP2,AKT1,CDC20,PKMYT1,DUSP4,DAG1,SNX12,SOCS3,DNAJC10,IDE,PTPRJ,STK38,CORO1C,NRG1,RGS14,ARFGEF3,TNRC6C,PINK1,CPEB4,PSMD10,PKN1,TRIB2,GSTP1,TIPRL,SH2D4A,CD109,SNTA1,RNF128,PTEN,BMP7,CST3,UBE2J1,BAX,TRIM21,BUB1,CNOT6L,SPRY2,CRTAP,PSMB4,PLAUR,GCLC,FURIN,COL7A1,MAPK8IP1,CDK5RAP1,SWAP70,TIMP3,BANK1,SERPINA1,NMI,SPINT2,ARRB1,ITGAV,LRRK1,GPER1,UBE2C,CPEB2,HIPK3,PKIA,JARID2 |
| 9.310e-07 | -13.89 | regulation of multicellular organismal development | biological process | GO:2000026 | 1553 | 215 | 16441 | 1675 |
EMX1,ACACB,SSH1,LGR4,TSC22D3,EPHA4,RET,PLXNA1,CAMK1D,CCNB1,VASH1,PDGFB,FAM101B,GRM5,NCS1,CTGF,IL6ST,DPYSL2,MITF,DLG1,DUSP10,TACSTD2,NTN4,SEMA3G,CTTN,PACSIN1,TIAM1,RASGRP1,CYP1B1,ACVR1C,ITCH,TFAP2C,KLK6,ARHGDIB,LOXL2,SAV1,CDK1,POR,RHEB,DPYSL3,ENPP1,PLCG1,GPRC5B,HPSE,PLK2,LIMK1,HOXA9,TRAF3IP1,NKD1,BMP1,SP6,ITPKA,ARF6,HSPB1,MAFF,LZTS1,GRN,SEMA6B,RUNX2,SERPINE2,LGALS3,UBASH3B,SOX9,ETV5,PHLPP1,BMP2K,ITGA3,CA2,CYR61,GATA2,MEGF8,KIF13B,FLRT3,VASN,SORL1,TNFRSF12A,MYDGF,WNT3A,CCDC88A,GPR161,RIMS2,SOCS5,EPB41L5,MMD,ANO6,HMG20B,EPHA1,NPHP3,GNA11,NFIB,CDK5R1,FAS,SOX13,GNAS,PTPRF,NCOA3,SEMA4D,CSF1,TMEM30A,NFKBIA,SFMBT1,FAM213A,GDF11,SEMA3A,JAK3,RARG,XDH,EGLN1,GAS2L1,FOXO6,NF2,GRHL2,HOXB7,IL15,INPP5D,TP53,ERBB2,IL27RA,OSR2,PRKACA,EMP2,TNFSF9,PDGFA,CCND1,SP100,KIF14,BCL6,CDKN1B,CDH3,DAB2IP,DIXDC1,TWIST1,NOTCH3,TMEM64,ETV4,DVL2,SEMA3B,SSH3,TIMP2,RIPK2,AKT1,CCSAP,CDC20,HTATIP2,CD40,DAG1,FZD7,ARHGAP35,BHLHB9,AXL,PTK7,SIPA1L1,INPP4B,EFNA5,NRG1,IRF7,RGS14,COBL,BIN1,WASF3,ANXA3,CTHRC1,NKX3-1,ADGRG1,CIT,LRP4,TGFBR1,CRABP2,ETS1,SRPX2,SIX4,ADGRB2,PPP2R3A,FZD6,HDAC9,CD109,CTNNBIP1,PTEN,BMP7,MYCL,KIAA0319,TFAP2A,BAX,MAPK11,CITED2,IQGAP3,SYK,TRIM62,TLE6,HES1,TGIF1,RHOA,ASPM,RAPGEF2,PIK3R1,GRIN1,RGCC,PRICKLE1,FOS,CD83,CDK5RAP1,HLA-B,FAT4,FGFR2,ACVRL1,NR1D2,TBX18,ERAP1,PPP2R3C,GPER1,OSR1,SOX8,ARSB,NDFIP1,L1CAM |
| 9.515e-07 | -13.87 | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | MSigDB lists | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 100 | 27 | 17758 | 1761 |
ARHGAP11A,HES1,CENPA,DLGAP5,FOXM1,TSC22D3,PTTG1,CDC20,CCNF,CCNB1,FOS,SLC20A1,CDK1,IER3,SLC25A4,CTGF,FOSB,NFKBIA,BCL6,AURKA,NR4A2,CENPE,NOTCH3,ZMIZ1,CCNB2,UBE2C,COL16A1 |
| 9.548e-07 | -13.86 | response to endogenous stimulus | biological process | GO:0009719 | 1545 | 214 | 16441 | 1675 |
CASP3,UGT8,SSH1,NRG2,F11R,PSME1,ITPR2,PDGFB,SDC1,SPTB,CALM2,ZFYVE16,SESN3,PSMD1,CTGF,SHC3,ZCCHC12,DPYSL2,KLF3,FOSB,STEAP2,PIK3CA,ABCA2,AKR1B1,CLDN4,PIK3CD,RASGRP1,THRB,CITED4,ACVR1C,CASP9,EZR,AGO4,PRKAR2B,IDH1,POR,RHEB,PIAS3,MDK,ENPP1,PLCG1,MAP2,NOD2,CAB39,HDAC1,EIF4EBP2,ADIPOR1,GAB1,NR2C2,RRAGD,PRKAA2,GRN,RUNX2,RASA2,DGKQ,SOX9,CALM3,PHLPP1,TFAP4,ITGA3,CA2,IGF1R,MEGF8,FLRT3,COL6A1,C10orf54,NCAM1,PAQR7,EPB41L5,RGMB,CALM1,STRADB,ELK1,PSMA4,RASA1,FAS,FECH,GNAS,MMP15,NCOA3,PRKAG2,PHLPP2,NFKBIA,ITPR1,SH3BP4,AURKA,NR4A2,LTBP2,JAK3,COL16A1,RARG,EHD1,GAS2L1,SPRED1,SORBS1,SLC2A4,NQO1,FOXM1,THRA,IQGAP1,PSME2,TP53,ERBB2,BCL2L1,PRKACA,ZFYVE9,PDGFA,CCND1,ATP6V0B,ACAP2,CDH1,SRR,CDKN1B,DAB2IP,GOT1,PDE4D,RASGEF1A,NR2C1,FRS3,SIRT1,TIMP2,RIPK2,AKT1,PTPRU,PRKCQ,ERBB2IP,ITPR3,DAG1,CASP4,SOCS3,IRS2,DUOX1,IDE,ATP1A1,JAK1,RBL1,SLC27A1,NRG1,SPTBN5,LTA4H,NR3C2,ABCA1,ANXA3,NKX3-1,TNRC6C,SORT1,CPEB4,LRP4,GABRG2,PSMD10,SELL,TGFBR1,GDF15,ETS1,FGF19,HDAC9,ADRBK1,PTEN,BMP7,CST3,FUT8,TOX2,BAX,CD9,TMBIM6,IGFBP2,KLF9,ERBB3,CITED2,SYK,SPRY2,MYO5A,NCOA2,GCNT1,PDGFC,TGIF1,RASGRF1,RHOA,SHMT1,PSMB4,NR3C1,RAPGEF2,NR4A1,GCLC,PIK3R1,GRIN1,PPARA,FURIN,GGH,RUNX3,YES1,FOS,BBS2,BCAR1,GPLD1,CTSL,PITX2,TIMP3,PLOD2,FGFR2,ACVRL1,NR1D2,TWSG1,CTSV,NR4A3,GRIN2D,GPER1,HOXB13,PLOD3,ARSB,TBC1D4,CPEB2,ABCG1,RGMA |
| 9.650e-07 | -13.85 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1433 | 196 | 17775 | 1757 |
CASP3,PPM1J,EPHA4,RET,NRG2,PDGFB,DNER,CARD10,KREMEN1,GRM5,WEE1,RPS6KA2,CNTRL,MKRN3,MITF,FOSB,PIK3CA,DUSP10,PIK3CD,TLN2,TIAM1,TIPARP,PLK1,CELSR2,ACVR1C,ITCH,USP18,CASP9,PRKAR2B,ROR1,SAV1,PPP1R14C,CCNF,ADRBK2,RHEB,EDNRA,PIAS3,PLCG1,NEIL1,GPRC5B,HOXA9,HDAC1,PIK3C2B,TRAF5,HSPB1,GAB1,HOXC13,PRKAA2,LASP1,PARP12,RASA2,ETV5,RAB23,MERTK,PSIP1,MECOM,OTUD1,IGF1R,ZNRF2,NEK2,PIM1,ZRANB1,SOCS5,DDB2,ELK3,STAT4,AMER1,ELK1,STEAP1,G2E3,RASA1,FAS,GNAS,MAPKAPK2,PRKAG2,ETS2,ITPR1,NFKBIA,AURKA,YOD1,EGFL7,PLD1,NDE1,MAP3K5,JAK3,RARG,USP43,LMO7,PLA2G4A,SPRED1,NF2,IQGAP1,RALBP1,TP53,ERBB2,MRAS,RNF182,BCL2L1,PRKACA,DDR1,STIL,REPS1,PDGFA,CCND1,SS18,MUC16,CDH1,PLCG2,BCL6,CDH3,CDKN1B,TWIST1,NOTCH3,EPHB4,ETV4,DVL2,MAP3K3,AKT1,FZD4,SEPT6,PTGER4,PRKCQ,PKMYT1,CD40,DUSP4,ITPR3,FANCE,MAP3K6,CASP4,FZD7,SOCS3,IRS2,EPHA10,PPP2R5A,JAK1,PTK7,STK38,AXL,NRG1,ABCA1,LIFR,MAPK12,IGFBP6,FRMD6,HERC5,TGFBR1,PKN1,ETS1,FGF19,PPP2R3A,FZD6,PDIA4,WWP2,KIF5B,DIRAS3,DTX3L,PTEN,MYCL,SGK3,BAX,ATP8B1,SGK1,MAPK11,IGFBP2,BUB1,WWP1,ERBB3,SYK,SPRY2,NCOA2,PARP9,RASGRF1,PDGFC,HES1,RHOA,BCL9,AMFR,RAPGEF2,RC3H2,PIK3R1,FURIN,UBE2A,MAML2,FOS,BCAR1,MAPK8IP1,CNTNAP1,FGFR2,RND3,RAP2C,DTX4,PPM1H,OTUB2,ARRB1,FZD5,GEM |
| 9.668e-07 | -13.85 | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | 208 | 44 | 17758 | 1761 |
UNKL,MYL9,PCOLCE,ZNF395,DEPDC1,CALB2,PKP2,MGAT5B,TRIB2,SDC1,LTBP3,SYTL2,PLS3,CDKN2C,TNS3,SESN3,AP1M2,CALD1,DACT1,VASN,ATP8B1,RTKN2,NTN4,TMEM37,NPTXR,LRP11,SCARA3,MYBL1,SEMA3B,ATL1,FADS2,S100A4,TNS1,LRRC1,GLT8D2,NFIB,ENDOD1,ALDH3B1,TIMP3,WIPI1,MATN2,HDAC1,COL16A1,OCLN |
| 9.693e-07 | -13.85 | small GTPase mediated signal transduction | biological process | GO:0007264 | 799 | 124 | 16441 | 1675 |
MYL9,ARHGAP11A,SPRED1,SPC25,NF2,TRIP10,RALBP1,PSME2,IQGAP1,NDC80,TP53,ERBB2,NRG2,NUF2,MRAS,PSME1,PDGFB,CENPN,SPTB,EPS8L2,ARHGEF16,PDGFA,CALM2,RAB15,PSMD1,CDH1,SHC3,KIF14,BCL6,CDKN1B,DAB2IP,RAB20,CTTN,MYH14,ARL4D,RASGEF1A,RAB27B,TIAM1,RASGRP1,DVL2,FRS3,CHP1,PLK1,DOCK4,CENPA,CDC20,ARFRP1,ARHGDIB,RAB38,DOCK5,ARF4,ABR,RHEB,ARHGAP35,IRS2,JAK1,LIMK1,PLK2,SPTBN5,NRG1,ARF6,MYL12B,FGD1,MAPK12,ARHGEF3,ARAP3,ARHGEF11,ADGRG1,RASA2,CENPI,CIT,EPS8,ARL4C,CDCA8,RAB23,CALM3,PSMD10,NCKAP1,RAB6A,PKN1,FGF19,DIRAS3,RALGPS2,FAM13B,BUB1,MAPK11,ERBB3,IQGAP3,NCAM1,NUP85,NCOA2,FARP2,RASGRF1,RAB3B,ZWINT,ARAP2,RHOA,PSMB4,RAPGEF2,CALM1,GRIN1,DIAPH2,STRADB,PSMA4,RASA1,RASGRP2,ARHGAP24,MAPKAPK2,BCAR3,RND3,FGFR2,RAP2C,RHOBTB2,GRIN2D,CENPE,LRRK1,PLD1,GEM,NDE1,ARPC2,JAK3,ARHGEF9,ARHGEF4,DOCK9 |
| 9.770e-07 | -13.84 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | 106 | 28 | 17758 | 1761 |
DOCK4,TIMP2,EPAS1,TACC1,SAT1,ETV5,MYEOV,IL18,IGSF8,PRSS22,MUM1L1,COL12A1,CA2,DHRS2,CDCA7L,FAM110C,OPN3,SGK3,NTN4,CADPS2,SYT13,PLD1,MYBL1,ULBP2,ZNF365,ISOC1,S100A6,CYP1B1 |
| 9.779e-07 | -13.84 | MODULE_19 | MSigDB lists | MODULE_19 | 306 | 58 | 17758 | 1761 |
MYL9,BIN1,PCOLCE,PAPSS2,ALDH6A1,IGFBP6,CDKN1C,HSPG2,EPAS1,NQO1,IQGAP1,CALB2,TMX4,ITPR2,TRIB2,SEPP1,MERTK,TSPAN7,CCND1,CDKN2C,NOV,ST5,PLCG2,COL6A1,FOSB,AOX1,BCL6,SGK1,ALDH7A1,IFIT1,NCAM1,CITED2,ALDH3A2,RIMS2,FADS2,SGCE,CD55,COL6A2,NR4A1,CBX6,ACO1,TCF7,MCFD2,FOS,CYB5A,CDK5R1,FUCA1,HLF,TIMP3,AGPAT2,PVRL2,SCG2,ITGA7,ITPR1,TCEAL4,SLC4A3,ABCB1,TLE1 |
| 9.792e-07 | -13.84 | GSE17721_12H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDM_UP | 188 | 41 | 17758 | 1761 |
PLA2G4A,MYL9,CCDC109B,FAM92A1,IL15RA,ITGA6,PDIA3,PHLDA1,TNFSF9,FGF19,NRP2,APPBP2,PLS3,RCN1,PDGFA,IGSF9,CTSC,FRYL,MITF,PAPSS1,TPST1,ECI2,RAB20,MINPP1,CCDC88A,PMPCB,TIMP2,RIPK2,TNIP1,USP18,BCL9,NUSAP1,PSMA4,TRAF5,NDST3,PTGES,TOB1,CPPED1,CYBRD1,JARID2,RRAGD |
| 9.792e-07 | -13.84 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | 188 | 41 | 17758 | 1761 |
NUDT6,LZTFL1,AK7,ATP8A1,POMGNT1,DHRS3,WWP2,SESN3,RALGPS2,CDH1,SORL1,ALDH7A1,NTN4,DLG3,F2R,PTPRE,MYRIP,CYP1B1,FAM69A,CYP26B1,SUSD3,ARAP2,MCTP1,MMD,TACC1,CORO2A,NPC2,DOCK5,FOS,ENDOD1,BANK1,PPP2R5A,STK38,SIPA1L1,ABCB1,SERPINB6,REEP4,ARSB,IFIH1,NRBP1,XDH |
| 9.831e-07 | -13.83 | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | 72 | 22 | 17758 | 1761 |
ANXA3,LASP1,TM2D2,PRSS23,MORC4,LOXL2,LGALS3BP,NRP2,DPYSL3,PTPRF,GPRC5B,PLK2,CORO1C,CALD1,MATN2,FAM83D,AKR1B1,CD70,TRAM1,PTGES,DCBLD1,SULF2 |
| 9.966e-07 | -13.82 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 215 | 45 | 17758 | 1761 |
ANXA3,UPF3B,SOX9,ATP2C2,MTL5,ARFGEF1,LTBP3,CARD10,LGALS3BP,IL17RB,SCNN1A,RPS6KA2,IGF1R,EFR3A,FRYL,IL6ST,AIM1,DLG1,CDH3,ACOX2,BTBD3,CYP1B1,WBP5,LAMP2,CPD,NFE2L3,IFITM3,TACC1,RAPGEF2,PIK3R1,SYBU,RAB38,ALCAM,MAPKAPK2,AP1AR,SCARB2,MFAP3L,RBM47,PDLIM3,DHRS2,NAT1,NMI,INPP4B,IFIH1,IFI6 |
| 9.973e-07 | -13.82 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 853 | 128 | 17758 | 1761 |
CCNI,HECA,SSH1,TSC22D3,CUL4B,RET,TAP1,IL18,F11R,MORF4L2,ITPR2,ISOC2,SIPA1L2,METTL7A,STIM1,PIK3CA,TMEM143,DUSP10,SNX16,CTTN,PTPRE,DDX59,TRIM8,CD55,NFE2L1,IDH1,PLCH1,CARHSP1,MID1IP1,PTER,RAB11FIP1,SERPINB6,MAFF,CDK17,ALDH6A1,HLA-E,HLA-F,ZCCHC24,ETV5,SLC36A4,B4GALT4,TTYH3,PSIP1,BMP2K,GNS,DAZAP1,SLC16A6,C10orf54,NCEH1,C9orf9,GFPT1,DDB2,IFIT3,NPHP3,FAS,NCOA3,ITPR1,STK39,NDE1,SERPINB1,RNF146,SLC25A24,NQO1,ARMCX3,CAST,FTH1,TMEM170B,PHLDA1,RCN1,SP100,LMO4,BCL6,PDE4D,SCYL3,CTH,FOXJ2,PTGER4,UTRN,CD40,MYL12A,DNAJC10,JAK1,CDK19,TRIOBP,ST3GAL1,ANXA3,CPEB4,BLVRB,GNE,MIER3,TGFBR1,TRIB2,ETS1,HLA-A,H1FX,DNAJB9,HDAC9,SLC25A36,CCDC92,IRF2BPL,E2F7,TMEM87B,GNB5,LLGL2,FAM63A,KLF9,SGCB,SYK,MYO5A,TGIF1,ARAP2,PLSCR1,NR3C1,RAPGEF2,SNTB1,BSDC1,KLHL2,NR1D2,ARRB1,ERAP1,CCDC69,PPP2R3C,ITGAV,TBC1D4,ARHGEF9,CPEB2,GOLGB1,ESYT2 |
| 1.004e-06 | -13.81 | DAP12 signaling | REACTOME pathways | R-HSA-2424491 | 325 | 63 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,HLA-E,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PDGFB,PRKACA,FGF19,SPTB,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PLCG2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CASP9,PIK3R1,CALM1,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,JAK1,PPP2R5A,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3,GAB1 |
| 1.008e-06 | -13.81 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 378 | 70 | 11866 | 1235 |
CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,CAMK1D,GRK6,PRKACA,DAPK2,WEE1,RPS6KA2,PASK,PLK4,EPHB4,PLK1,AKT1,ACVR1C,PRKCQ,PKMYT1,MAP3K6,ADRBK2,STK17B,CDK1,JAK1,STK26,CDK19,PLK2,STK38,AXL,LIMK1,MAPK12,PRKAA2,LMTK3,CDK17,NUAK1,CIT,TGFBR1,TEC,PKN1,MERTK,ADRBK1,IGF1R,CDK16,MAP3K9,PRKG1,DAPK1,SGK3,SGK1,MAPK11,BUB1,PIM1,SYK,TESK1,EIF2AK1,EPHA1,YES1,PDIK1L,STK17A,MAPKAPK2,ACVRL1,FGFR2,CSNK1G1,AURKA,STK39,CDK18,MAP3K5,JAK3,HIPK3,MELK |
| 1.009e-06 | -13.81 | AKT_UP.V1_UP | MSigDB lists | AKT_UP.V1_UP | 162 | 37 | 17758 | 1761 |
MAN2B2,TPRN,UGT8,CAMKK1,FBXO6,TMPRSS4,PARM1,SGPL1,TMCC3,CXCL16,DUSP10,VAT1,TNFRSF12A,TACSTD2,GOT1,IFIT1,LGMN,MYO5B,CD55,PLSCR1,GUSB,C3orf52,AK4,PDK3,IFIT3,MMP15,SLC6A6,PTPRJ,TJP3,GDE1,PLK2,SECTM1,CLMN,SH3BGRL2,MAL2,UNC5B,UBE2C |
| 1.027e-06 | -13.79 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1443 | 197 | 17775 | 1757 |
CASP3,PPM1J,EPHA4,RET,NRG2,PDGFB,DNER,CARD10,KREMEN1,GRM5,WEE1,RPS6KA2,CNTRL,MKRN3,MITF,FOSB,PIK3CA,DUSP10,PIK3CD,TLN2,TIAM1,TIPARP,PLK1,CELSR2,ACVR1C,ITCH,USP18,CASP9,PRKAR2B,ROR1,SAV1,PPP1R14C,CCNF,IDH1,ADRBK2,RHEB,EDNRA,PIAS3,PLCG1,NEIL1,GPRC5B,HOXA9,HDAC1,PIK3C2B,TRAF5,HSPB1,GAB1,HOXC13,PRKAA2,LASP1,PARP12,RASA2,ETV5,RAB23,MERTK,PSIP1,MECOM,OTUD1,IGF1R,ZNRF2,NEK2,PIM1,ZRANB1,SOCS5,DDB2,ELK3,STAT4,AMER1,ELK1,STEAP1,G2E3,RASA1,FAS,GNAS,MAPKAPK2,PRKAG2,ETS2,ITPR1,NFKBIA,AURKA,YOD1,EGFL7,PLD1,NDE1,MAP3K5,JAK3,RARG,USP43,LMO7,PLA2G4A,SPRED1,NF2,IQGAP1,RALBP1,TP53,ERBB2,MRAS,RNF182,BCL2L1,PRKACA,DDR1,STIL,REPS1,PDGFA,CCND1,SS18,MUC16,CDH1,PLCG2,BCL6,CDH3,CDKN1B,TWIST1,NOTCH3,EPHB4,ETV4,DVL2,MAP3K3,AKT1,FZD4,SEPT6,PTGER4,PRKCQ,PKMYT1,CD40,DUSP4,ITPR3,FANCE,MAP3K6,CASP4,FZD7,SOCS3,IRS2,EPHA10,PPP2R5A,JAK1,PTK7,STK38,AXL,NRG1,ABCA1,LIFR,MAPK12,IGFBP6,FRMD6,HERC5,TGFBR1,PKN1,ETS1,FGF19,PPP2R3A,FZD6,PDIA4,WWP2,KIF5B,DIRAS3,DTX3L,PTEN,MYCL,SGK3,BAX,ATP8B1,SGK1,MAPK11,IGFBP2,BUB1,WWP1,ERBB3,SYK,SPRY2,NCOA2,PARP9,RASGRF1,PDGFC,HES1,RHOA,BCL9,AMFR,RAPGEF2,RC3H2,PIK3R1,FURIN,UBE2A,MAML2,FOS,BCAR1,MAPK8IP1,CNTNAP1,FGFR2,RND3,RAP2C,DTX4,PPM1H,OTUB2,ARRB1,FZD5,GEM |
| 1.029e-06 | -13.79 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | 195 | 42 | 17758 | 1761 |
GRN,LAMP1,MRC2,SORT1,NFKBIE,UGP2,CPT2,SDC4,ABCG2,NDRG2,FTH1,MRAS,CTSZ,NANS,CENPN,ARHGEF10L,PDGFA,ATP6V0B,FAM46A,CTSC,PLCG2,ADCK2,CD9,TACSTD2,CTTN,SPRY2,CKAP4,CPD,PDGFC,LOC81691,CDA,PRKAR2B,RAB38,BLVRA,STX3,CD83,FUCA1,PRCP,CSF1,NR4A3,ACOT7,CD33 |
| 1.029e-06 | -13.79 | response to fibroblast growth factor | biological process | GO:0071774 | 320 | 61 | 16441 | 1675 |
SPRED1,RUNX2,TNRC6C,PSME2,IQGAP1,RASA2,CALM3,NRG2,ERBB2,PSMD10,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,CTGF,SHC3,PTEN,FLRT3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,ITPR3,ELK1,PSMA4,RASA1,IRS2,PLCG1,JAK1,FGFR2,PHLPP2,ITPR1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.061e-06 | -13.76 | identical protein binding | molecular function | GO:0042802 | 1181 | 170 | 16491 | 1673 |
ADD1,CRYM,EPHA4,HEXB,NDC80,TAP1,DHX8,OAT,PDGFB,ERP29,SLC8B1,BARD1,SLC9A7,DAPK2,HSF2,STIM1,IL6ST,CABP1,ALDH1A3,CLDN4,SNX16,PTPRE,S100A13,APOBEC3G,SMAGP,RASGRP1,ATL1,TRIM8,CDA,CR2,PRKRA,IDH1,TP53I3,TYSND1,OPTN,TRIM9,ENPP1,DNM1L,ADIPOR1,GLA,HSPB1,RAP1GAP,E2F8,DDX58,HJURP,ABCG2,GPSM2,FBLN1,S100A2,ANO1,MECOM,TFAP4,IGF1R,PIK3AP1,BHLHE41,FLRT3,MAP3K9,DAPK1,SELK,AHCY,NCAM1,ALS2CL,CCDC88A,RGMB,ANO6,PIP4K2C,VWA1,EIF2AK1,IFIT3,PLIN5,FAS,NUDT16,PLEKHH2,UAP1,PVRL2,DCK,CSF1,PRPS2,NFKBIA,SH3BP4,S100A5,NR4A2,MAP3K5,NDE1,HOOK1,NRBP1,TMEM173,XDH,LZTFL1,UGP2,NQO1,S100A11,TRIP10,THRA,TP53,COL18A1,ERBB2,BCL2L1,MNS1,PDGFA,APLP2,SP100,SRR,PLK4,BRI3,GOT1,TWIST1,DAB2IP,ECE1,NAGA,NR2C1,DVL2,SEPHS1,FRS3,SIRT1,CLCN3,GCA,AKT1,RIPK2,FZD4,S100A4,GTF2A2,ALDH5A1,IDE,STK26,BHLHB9,TLE1,SLC27A1,ANXA9,BIN1,PACSIN2,LRP4,SRPX2,TOP2A,FOXP2,E2F7,CARD8,CTSC,PTEN,CST3,TFAP2A,BAX,TRIM21,ABCD1,ERBB3,TPCN1,S100A6,AMOTL2,PVRL4,HES1,SUN2,PDGFC,SHMT1,FBLN5,NADK2,COL7A1,LEPR,PRDX4,PITX2,SERPINA1,RAB11FIP2,FGFR2,TBX18,NR4A3,LRRK1,USF2,L1CAM,ACOT7,ESYT2,ABCG1 |
| 1.064e-06 | -13.75 | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | MSigDB lists | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | 243 | 49 | 17758 | 1761 |
GRN,ENO2,IGFBP6,HSPG2,CD63,DAP,XYLT1,EPHA4,ETV5,EPS8,CACNA2D2,ERBB2,VASH1,DDR1,FBLN1,TSPAN7,PARM1,DAPK2,BTG3,ADORA1,CTGF,GNB5,TRPC1,VAT1,TAGLN2,MANF,ZNF365,S100A13,NEB,PLK1,SGCE,CELSR2,PRSS23,SLC39A8,STAT4,SAT1,SLC11A2,EDNRA,FRMD4B,DPYSL3,MDK,NUCB1,TIMP3,FGFR2,KCNK1,FAM114A1,UNC5B,PLOD3,AFAP1 |
| 1.073e-06 | -13.75 | HOXA9_DN.V1_UP | MSigDB lists | HOXA9_DN.V1_UP | 182 | 40 | 17758 | 1761 |
SLC35D2,ARHGEF3,CCDC109B,PARP12,ARL4C,IL13RA1,GDF15,VASH1,OAT,TSEN34,AKIRIN1,GNS,ZFYVE16,TYMP,FRY,SGK3,BAX,SORL1,MARCH2,PTPRE,SNX10,CYP1B1,OSTM1,COQ10B,PTGER4,GALNT7,FNDC3A,SESN1,FOS,TP53I3,CRISPLD2,FAS,FUCA1,HPSE,RBM47,PLK2,NOD2,STK39,NDFIP1,TOB1 |
| 1.073e-06 | -13.75 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 182 | 40 | 17758 | 1761 |
CD99,TXN,IL15RA,DNAJC3,ITGA6,TGFBR1,DNAJB9,HDAC9,TMEM63A,IL17RB,MARCH8,ATP6V0B,FAM46A,SGK3,PCYOX1,WWP1,RTKN2,ESPN,SELK,FAR2,MYBL1,TRAM1,ETV7,SMAGP,ACVR1C,LYRM1,SYNE2,BLVRA,DAG1,FAS,OPTN,IRS2,HS6ST1,NFKBIZ,SERPINI1,F2RL1,NR3C2,AHR,NIPA1,SNX30 |
| 1.093e-06 | -13.73 | Signaling by the B Cell Receptor (BCR) | REACTOME pathways | R-HSA-983705 | 198 | 44 | 8202 | 867 |
TNRC6C,NFKBIE,PSME2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PDGFB,FGF19,SH3KBP1,CALM2,PDGFA,PSMD1,PTEN,PIK3AP1,STIM1,PLCG2,PIK3CA,CDKN1B,TRPC1,PIK3CD,ERBB3,SYK,RASGRP1,AKT1,PSMB4,NR4A1,CASP9,PIK3R1,CALM1,AGO4,ITPR3,PSMA4,IRS2,PLCG1,FGFR2,PHLPP2,NFKBIA,ITPR1,NRG1,GAB1 |
| 1.097e-06 | -13.72 | Wnt signaling pathway | biological process | GO:0016055 | 244 | 50 | 16441 | 1675 |
PRKAA2,CTHRC1,LGR4,LRRFIP2,LRP4,NDRG2,AES,NOTUM,GRK6,SDC1,APC2,KREMEN1,FZD6,PPP2R3A,HMGXB4,MESDC2,CTNNBIP1,CCND1,PTEN,DACT1,MITF,PLCG2,CDH3,DIXDC1,ZRANB1,WNT3A,DVL2,AMOTL2,CELSR2,PTPRU,FZD4,BCL9,AMER1,TCF7,PYGO1,ROR1,NPHP3,FZD7,CXXC4,PTK7,PLPP3,CSNK1G1,NKD1,RYK,TRABD2A,TLE1,FZD5,RARG,RNF146,ZBTB33 |
| 1.104e-06 | -13.72 | membrane region | cellular component | GO:0098589 | 1097 | 158 | 17570 | 1756 |
CASP3,RET,EPHA4,SYTL4,HDAC6,PJA2,PDGFB,NCS1,EPCAM,CABP1,DLG1,CLDN4,TRPC1,TACSTD2,RP2,CTTN,PACSIN1,MYRIP,LAMP2,SGCE,CD55,EZR,PRKAR2B,ARF4,ENPP1,HPSE,DNM1L,KCNK1,ATP7B,NOD2,PRKCDBP,PIEZO1,UNC5B,ARF6,LZTS1,DDX58,SCN5A,BVES,ITGA6,CNTNAP2,NCKAP1,SLC1A3,DHRS3,ANO1,ITGA3,CA2,IGF1R,ZNRF2,KCNN4,FLRT3,PIKFYVE,SLC12A2,RIMS2,GPR161,ABCC1,EPB41L5,RGMB,SPATA13,SCRIB,ANTXR1,STX3,FAS,RASGRP2,EPN3,GABRD,TJP3,SLC4A4,PHLPP2,TMEM30A,SH3BP4,STK39,MAL2,ATP1B3,PLD1,SHROOM2,RUSC1,PROM2,EHD1,SPRED1,SLC2A4,SORBS1,TCTN2,NF2,ST14,ERBB2,KCTD12,PRKACA,EMP2,APC2,REPS1,EPS8L2,SCNN1A,CDH1,CNNM4,PDE4D,DLG3,RAB27B,F2R,CYS1,SYNE2,UTRN,SLC11A2,ERBB2IP,ATP1B1,DAG1,GABARAPL1,DUOX1,PTPRJ,ATP1A1,STK26,SHROOM3,CORO1C,SIPA1L1,SLC27A1,SPTBN5,NRG1,EFNA5,RGS14,ABCA1,TTC8,SORT1,PACSIN2,LRP4,SDC4,EPS8,GABRG2,EFHD2,SRPX2,EFNB1,FZD6,SNTA1,ADORA1,ANKS1B,PTEN,CD9,ATP8B1,IGFBP2,ERBB3,SPRY2,AMOTL2,DLGAP1,RHOA,PLSCR1,CRB3,PLAUR,RAPGEF2,GRIN1,FURIN,AIF1L,BBS2,ARRB1,GRIN2D,ITGAV,GPER1,L1CAM,OCLN,CYBRD1,ARHGEF4 |
| 1.119e-06 | -13.70 | positive regulation of cell communication | biological process | GO:0010647 | 1574 | 217 | 16441 | 1675 |
ILDR1,TXN,LGR4,EPHA4,RET,ARFGEF1,LMCD1,NRG2,PSME1,IL18,NENF,HDAC6,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,SIVA1,TSPAN6,IL31RA,AKR1B1,SLC39A10,MYRIP,S100A13,RASGRP1,CYP1B1,TRIM8,SH3BGRL,KLK6,PRKRA,CDK1,POR,RHEB,PLCG1,GPRC5B,HPSE,AGPAT2,DNM1L,ANKRD6,PLK2,MADD,NKD1,FAM110C,NOD2,PRKCDBP,ADIPOR1,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,RRAGD,PRKAA2,LASP1,BMF,CDKN1C,SERPINE2,SCOC,RASA2,SOX9,CALM3,SLC1A3,TNFRSF19,IL18R1,ANO1,KIAA1161,TFAP4,CA2,IGF1R,CYR61,PIK3AP1,KCNN4,MAP3K9,MDFIC,TNFRSF12A,MYDGF,C10orf54,NCAM1,ZRANB1,WNT3A,RIMS2,MDFI,KLK5,CALM1,AMER1,PIP4K2C,PDE5A,PSMA4,STX3,RASA1,FAS,GNAS,MAPKAPK2,SEMA4D,PELI2,CSF1,NLRC5,GDF11,MAP3K5,JAK3,TOB1,RNF146,RUSC1,XDH,SPRED1,SORBS1,AVPI1,IL15,PSME2,TP53,ERBB2,BCL2L1,EMP2,BCAP31,PDGFA,NOV,ST5,RNF220,DACT1,CDH3,DAB2IP,DIXDC1,RASGEF1A,F2R,NR2C1,DVL2,FRS3,SULF2,CTH,MAP3K3,SIRT1,PPIF,TIMP2,RIPK2,AKT1,FZD4,S100A4,PRKCQ,ITPR3,CD40,MAP3K6,FZD7,IRS2,PTPRJ,JAK1,AXL,SECTM1,NRG1,IRF7,SPTBN5,RGS14,PINK1,NKX3-1,CD63,ADGRG1,TSPAN15,EPS8,PDIA3,PSMD10,TGFBR1,GDF15,PKN1,FGF19,PPP2R3A,NEO1,KIF5B,ADORA1,CTSC,PTEN,BMP7,BAX,PLEKHF1,SLC44A2,BUB1,MAPK11,ERBB3,CITED2,IQGAP3,SYK,TRIM62,SPRY2,HES1,RASGRF1,RAB3B,RHOA,PSMB4,ASPM,RAPGEF2,PLAUR,PIK3R1,RC3H2,GRIN1,LITAF,FURIN,MAPK8IP1,GPLD1,CNTNAP1,BANK1,FGFR2,ACVRL1,TWSG1,DBI,RYK,ARRB1,GRIN2D,GPER1,LRRK1,FZD5,NDFIP1,L1CAM |
| 1.120e-06 | -13.70 | DAP12 interactions | REACTOME pathways | R-HSA-2172127 | 340 | 65 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,PSME1,ITPR2,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,JAK1,PPP2R5A,NRG1,SPTBN5,GAB1,TNRC6C,RASA2,HLA-E,CALM3,PSMD10,PHLPP1,FGF19,ADRBK1,PTEN,ERBB3,HLA-C,NCAM1,SYK,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PSMA4,RASA1,HLA-B,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,JAK3 |
| 1.122e-06 | -13.70 | GREENBAUM_E2A_TARGETS_UP | MSigDB lists | GREENBAUM_E2A_TARGETS_UP | 33 | 14 | 17758 | 1761 |
TOP2A,CDKN2C,CA2,FGFR2,PLK4,AURKA,BUB1,NUSAP1,CCNB1,ANLN,CCNB2,KIF11,SLC12A2,WBP5 |
| 1.133e-06 | -13.69 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 189 | 41 | 17758 | 1761 |
DDX58,PARP12,IL15RA,HLA-E,TAP1,HERC5,SAMD9,HERC6,BARD1,LGALS3BP,RABGGTA,NOV,SP100,TRANK1,DRAM1,BCL6,TRIM21,IFIT1,OAS3,LAMP3,MX1,RIPK2,PLSCR1,IFITM3,USP18,RAPGEF2,LYRM1,AK4,IFIT3,PSMA4,CASP4,PRDX4,SOCS3,ETS2,C19orf66,NMI,SLC2A6,IRF7,IFIH1,APOL2,IFI6 |
| 1.133e-06 | -13.69 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | 189 | 41 | 17758 | 1761 |
GRN,SORT1,TXN,RUNX2,CRYM,ST14,HEXB,HERC5,TEX2,MGST2,NUCB2,SLC20A1,GSTP1,IL18R1,BCAP31,RAB15,CTSC,SIVA1,MGAT4A,RRBP1,CST3,DAPK1,MDFIC,AHCY,MARCH2,EGLN3,PTPRE,NAGA,SEC61B,ALDH2,CBX6,LHFPL2,MYL12A,MAPKAPK2,SCARB2,DCK,CORO1C,SH3BP4,IRF7,FHL1,TBC1D4 |
| 1.147e-06 | -13.68 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 13006 | 1368 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,ETS2,CLMN,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,GRK6,MGST2,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,ZNF365,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,XRCC6BP1,ZNF618,SNX12,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,BTN3A1,CTSZ,CTNNBIP1,DIRAS3,FUT2,ITGB8,MGAT4A,FAM20B,FAM102A,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PDK3,PRX,RASGRP2,FOXD2,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,STIL,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GDF15,HMGN3,LBR,VPS26A,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,NFE2L3,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,STIM1,OSBPL3,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,METAP2,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TNFRSF19,TSPAN7,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,ST14,CCDC110,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,TSPAN1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,TMEM144,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,CCDC149,ZNF704,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,PBX3,DNAH3,EFNB1,FGF19,HLA-A,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,ANKFN1,TRPC1,MYRIP,BTBD3,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,COL16A1,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,CASP4,ARHGAP35,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,RBMS2,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ERAP2,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,E2F8,GAB1,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,GNS,FAM189A1,FAM13B,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,ANO9,NUCB2,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,CALD1,ADAM15,MAPK11,WWP1,NPTXR,TPCN1,S100A6,CRTAP,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,DCBLD1,CYBRD1,MYL9,SIGIRR,TRIM2,FAM199X,PPM1J,EPHA4,FHDC1,NDC80,HDAC6,PDGFB,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,ZCCHC24,UBASH3B,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,CHSY3,CYP26B1,MRPS33,CORO2A,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,H1F0,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,CYP26A1,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,BLVRB,GABRG2,DSE,CRABP2,SIRPA,SLC9A2,PPP2R3A,CCDC92,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,AMFR,PPARA,CCDC34,FNDC3A,BCAR1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,NCS1,SESN3,CTGF,ELMO2,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,XKR8,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,RBM47,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,VEZT,FAM133B,GLT8D2,STX3,RASA1,DGKH,GABRD,PRKAG2,ISM1,DCK,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,TRIP10,NLRX1,S100A11,BROX,IQGAP1,RPS6KA1,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,CYB561,SPR,TEAD3,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,NCOA2,OSGIN1,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CPT2,HEBP1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,RHOBTB2,ALPK3,PITPNA,EGFL7,KLF7,PROM2,FAM92A1,IL15,PSME2,TDRKH,SLC25A48,SS18,SETDB2,FRYL,GOT1,TWIST1,RPN2,F2R,PDIA6,SCYL3,FRS3,ZNF525,SLC39A8,OSTM1,IGSF8,DUSP4,DOCK5,BFSP1,PEX2,VSIG10,LIFR,ANXA3,SORT1,POC1B,LRP4,FAM134A,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,MBNL3,LRRC66,OGDHL,KLHL2,HLA-B,C2orf70,OTUB2,HOXB13,SOX8,L1CAM,SNPH |
| 1.155e-06 | -13.67 | RUIZ_TNC_TARGETS_UP | MSigDB lists | RUIZ_TNC_TARGETS_UP | 150 | 35 | 17758 | 1761 |
GRN,KIAA1462,ATP9A,ZCCHC24,COL18A1,KCTD12,COL4A5,GDF15,TRIB2,SEPP1,PHLDA1,LTBP3,CTSC,METTL7A,BCL6,KLF9,HLA-C,ACSL4,CTDSP2,SAT1,BTN3A2,PDE5A,LDB2,EDNRA,GLCE,SCG2,WIPI1,PLK2,LRIG1,ARRB1,CTSA,ST3GAL1,IFIH1,LTA4H,GOLGB1 |
| 1.173e-06 | -13.66 | negative regulation of cellular component organization | biological process | GO:0051129 | 574 | 95 | 16441 | 1675 |
GAS2L1,LZTFL1,ADD1,THRA,PTTG1,EPHA4,ARFGEF1,TP53,BCL2L1,CCNB1,HDAC6,APC2,SPTB,IER3,RPS6KA2,LMO4,KIF14,VAT1,DAB2IP,ESPN,TWIST1,TACSTD2,SEMA3G,PACSIN1,SEMA3B,PLK1,PPIF,SIRT1,AKT1,CDC20,PTGER4,PIF1,CCNF,SLC25A5,DPYSL3,TRIM9,MID1IP1,PPP2R5A,PLK2,CORO1C,TRAF3IP1,TRIOBP,SPTBN5,TMOD2,ARF6,RAP1GAP,SEMA6B,PINK1,PACSIN2,LGALS3,CKAP2,CIT,DNAJB2,EPS8,LRP4,PSMD10,FAM21C,FBLN1,LMNA,CTNNBIP1,ITGA3,PTEN,BMP7,VASN,CST3,TBCD,KIAA0319,NEK2,SORL1,BUB1,WNT3A,TRIM62,SPRY2,RHOA,MFI2,RAPGEF2,RGCC,NUBP1,CDK5R1,ARHGAP24,AP1AR,PLEKHH2,SWAP70,FGFR2,SEMA4D,ACVRL1,AURKA,HMGA1,SHROOM2,SEMA3A,TBC1D4,UBE2C,ESPL1,JARID2,PROM2 |
| 1.186e-06 | -13.65 | GSE7460_TCONV_VS_TREG_THYMUS_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_UP | 196 | 42 | 17758 | 1761 |
EXPH5,DDX58,MFSD3,FBLIM1,ARHGEF11,ARL4C,TMEM170B,GRK6,SLC20A1,FAM101B,KREMEN1,FZD6,TMEM63A,OTUD1,ZCCHC12,ZFP36,CYP2S1,MITF,FAM102A,SGK1,TINAGL1,TRAM1,MYLIP,CTDSP2,SLC16A5,TIMP2,SLC35C1,FBXO9,ARHGDIB,NPC2,ELK1,NEURL1B,XKRX,KCNMB4,GPRC5B,ACVRL1,SLC9A6,P4HA2,RAP2C,APOL2,ZBTB33,CXorf56 |
| 1.191e-06 | -13.64 | KEGG_LYSOSOME | MSigDB lists | KEGG_LYSOSOME | 119 | 30 | 17758 | 1761 |
LAMP2,LAMP1,GAA,SORT1,CD63,GUSB,GGA1,HEXB,ASAH1,SLC11A2,CTSZ,NPC2,M6PR,FUCA1,GNS,ATP6V0B,SCARB2,AP1M2,ARSG,CTSC,GNPTAB,GALNS,ABCA2,CTSA,GLA,LGMN,ARSB,NAGA,GM2A,LAMP3 |
| 1.201e-06 | -13.63 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 687 | 107 | 17775 | 1757 |
CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,NDRG2,GRK6,CAMK1D,DPP8,PRKACA,DDR1,ABCD4,DAPK2,WEE1,CYP1A1,RPS6KA2,CDH1,PAPSS1,PIK3CA,PLK4,EPHB4,SCYL3,MYO5B,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,UTRN,PRKCQ,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,SOCS3,EPHA10,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MLKL,LIFR,MAPK12,GRN,PRKAA2,PINK1,BMF,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,TFAP2A,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SLC12A2,SYK,PGM1,PLEKHA6,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,STK17A,GNAS,MAPKAPK2,FAT4,ACVRL1,FGFR2,PHLPP2,SLC4A3,ALPK3,AURKA,CDK18,MAP3K5,ARPC2,JAK3,HIPK3,NRBP1,MELK |
| 1.217e-06 | -13.62 | lymph_node | COSMIC cancer mutations | lymph_node | 1781 | 235 | 17775 | 1757 |
EXPH5,LTBP1,ATP8A1,RET,CUL4B,NRG2,MORF4L2,ITPR2,BARD1,FAM46C,SLC20A1,KREMEN1,SPTB,SH3KBP1,ZFYVE16,WEE1,RPS6KA2,MUC4,CTGF,SHC3,CYP2S1,PAPSS1,ANKFN1,DLG1,AOX1,STEAP2,PIK3CA,ATRNL1,PIK3CD,CTTN,TMEM37,RCAN3,PTPRE,MYRIP,ZNF462,SPEF2,TRIM8,PBK,RGAG1,LDB2,PRKRA,IDH1,SESN1,PTGFRN,ZBTB7B,ARHGEF26,PLCG1,NEIL1,DNM1L,PLK2,MADD,PRDM5,PRKCDBP,ARRDC1,PIK3C2B,ARF6,CAPN1,HOXC13,PCSK5,CD99,ARAP3,MRC2,CDK17,CDKN1C,ITGA6,ETV5,CNTNAP2,SLC1A3,SAMD9,PM20D2,ADAMTSL4,TSPAN7,ANO1,PRRG4,ZNF432,UBE2Q2,IGF1R,FRY,FAM189A1,DAPK1,PRKG1,MAP3K9,CD70,PIM1,CACNA1D,PIKFYVE,NCEH1,ETV7,RIMS2,TRAK2,CHSY3,ADCK3,SALL4,PIP4K2C,MYBL2,TCF7,EIF2AK1,PDK3,SFXN5,PRX,FAS,MAPKAPK2,ISM1,PELI2,UTP14C,TMEM30A,DCK,ITPR1,NFKBIA,CLMN,AURKA,MAP3K5,JAK3,COL16A1,EGLN1,KLF7,LMO7,SPRED1,LZTFL1,NF2,IL15,IQGAP1,RPS6KA1,TMX4,TP53,COL18A1,ERBB2,TDRKH,GRK6,PRKACA,DDR1,APC2,CDS1,CCND1,MUC16,SCNN1A,PLCG2,BCL6,EPHB4,RASGEF1A,DLG3,PDIA6,SNX10,SCYL3,SEPHS1,MYO5B,MAP3K3,MX1,AKT1,UTRN,ATP1B1,DUSP4,DOCK5,MAP3K6,SP4,PRDM11,NIN,PPP2R5A,JAK1,PDLIM3,SHROOM3,CDK19,WFS1,PTK7,STK38,AXL,ZNF704,SPTBN5,MLKL,SYT13,NR3C2,ABCA1,LIFR,MAPK12,ARHGEF3,PINK1,ATP9A,GNE,EPS8,HAL,SLC25A43,ETS1,NEO1,SLC25A36,DIRAS3,FOXP2,MDM1,ADRBK1,CDK16,PTEN,BMP7,FAM102A,SLC44A2,SGK1,MAPK11,ERBB3,FAIM,CNOT6L,SGCB,SYK,RASGRF1,SYPL1,RAB3B,LCA5,RHOA,ARAP2,PSMB4,FAM160A1,NR3C1,PIK3R1,CXorf57,OGDHL,UBE2A,AK4,MAML2,YES1,GRTP1,KIF11,BBS2,MAPK8IP1,ARHGAP24,HLA-B,RPL12,SERPINA1,FAT4,PLOD2,TRIM69,FGFR2,ZNF214,SH3BGRL2,ETAA1,GRAMD1C,ITGAV,TBC1D4,TLL2 |
| 1.231e-06 | -13.61 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 355 | 67 | 8202 | 867 |
SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,NRG2,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,PPP2R5A,JAK1,SPTBN5,NRG1,GAB1,MAPK12,TNRC6C,RASA2,CALM3,PSMD10,PHLPP1,FGF19,ADRBK1,PTEN,MAPK11,ERBB3,NCAM1,RASGRF1,RHOA,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,ELK1,PSMA4,RASA1,MAPKAPK2,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,JAK3 |
| 1.235e-06 | -13.60 | PTCH1 (patched 1) | protein interactions | 5727 | 94 | 27 | 16036 | 1726 |
UGT8,ITCH,ITGA6,CASP9,CACNA2D2,COL18A1,GALNT7,PLXNA1,CCNB1,ARSK,CDK1,HLA-A,KIAA1161,CHPF,WWP2,ENPP1,ITGA7,IMPAD1,ABCA2,NETO2,CNNM4,WWP1,HLA-C,MGAT5,TMEM131,GCNT1,SULF2 |
| 1.240e-06 | -13.60 | YNGTTNNNATT_UNKNOWN | MSigDB lists | YNGTTNNNATT_UNKNOWN | 352 | 64 | 17758 | 1761 |
GRHL2,NDC80,CAMK1D,CENPN,TRIM68,SYTL2,WEE1,BTG3,RGS3,LMO4,LHX6,MITF,ATRNL1,DUSP10,ACSL4,PIK3CD,THRB,DOCK4,SMARCA2,COG2,RGAG1,KIF13A,ARHGDIB,ROR1,PPP1R14C,SP4,NFIX,PPP2R5A,RBM47,HOXA9,OVOL1,CPEB4,KLHL13,GABRG2,INTS8,CNTNAP2,SH2D4A,FOXP2,FLRT3,BHLHE41,CALD1,KLF9,CITED2,CLIP2,CYP26B1,RASGRF1,BCL9,AMFR,NUB1,PIK3R1,GRIN1,NFIB,GLT8D2,ACADSB,ITPR1,PGRMC1,CLMN,AURKA,CEP41,IFIH1,SEMA3A,TOB1,DEF6,DIS3L |
| 1.243e-06 | -13.60 | Signaling by FGFR4 | REACTOME pathways | R-HSA-5654743 | 313 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.243e-06 | -13.60 | Signaling by FGFR3 | REACTOME pathways | R-HSA-5654741 | 313 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.248e-06 | -13.59 | Signaling by ERBB2 | REACTOME pathways | R-HSA-1227986 | 320 | 62 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,YES1,ERBB2IP,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.263e-06 | -13.58 | binding | molecular function | GO:0005488 | 13878 | 1473 | 16491 | 1673 |
AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,FAM46C,CMTM6,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,RNF26,TIAM1,TIPARP,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,CADPS2,ALPK1,MYDGF,ZMYM1,DGKG,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,PLIN5,SLC4A4,ETS2,RAET1L,S100A5,CLMN,STK39,GDF11,TMEM159,CFAP20,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,RNF224,NQO1,INPP5D,CD82,PTTG1,C5orf30,GRK6,MVB12B,REPS1,APPBP2,RCN1,MUC16,CDH1,SH3BP1,ENPP5,LRP11,DLG3,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,XRCC6BP1,GTF2A2,SNX12,ZNF618,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,ISOC1,MAPK12,CTHRC1,TCAF1,DCAF7,ESRP1,SDC4,HABP4,BTN3A1,CTSZ,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,FAM20B,CST3,ZFAND4,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,OPLAH,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,CXorf57,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,TLL2,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NPNT,IL6ST,PAPSS1,PAPL,MITF,PASK,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,KDM4D,TRIM9,PLEKHG6,KCNMB4,KLF12,ZNF367,HOXA9,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,UBE2Q2,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,WNT3A,CKAP4,DPYSL5,PCDH1,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,SMCO4,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,PDGFA,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,MMP17,STK38,EFNA5,IRF7,SYT13,BIN1,ZMAT1,PINK1,TOR4A,CPEB4,CDH22,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,H1FX,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,METAP2,SPATA18,ACVR1C,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,THEMIS2,S100A2,PSIP1,MESDC2,C9orf69,LYPD3,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,AIM1,DAPK1,ADCK2,TMEM51,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,SOCS5,TRAK2,GFPT1,PRODH,KLK5,ADCK3,CALM1,NPC2,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,AGBL5,FAM83D,SFMBT1,CABIN1,CDK18,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,REPS2,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,CEP162,AMZ2,DDOST,NGFRAP1,TRIOBP,ZNF704,EFCAB14,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,PBX3,EFHD2,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SCML1,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,SIVA1,TRPC1,CTTN,MYRIP,SP5,CYP1B1,NLRP4,CENPA,ITCH,USP18,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,COL6A1,LIMCH1,HLA-C,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,NUBP1,PDIK1L,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,SHROOM2,TMEM14A,JAK3,TOB1,APOL2,COL16A1,RARG,AFAP1,SNX30,LMO7,CCNE2,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,SEPHS1,CHP1,PTPRU,C3orf52,GLO1,CD40,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,INTS8,TRIB2,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,LEPR,ENDOD1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,RAB3IL1,CD33,ABCG1,ACACB,IL15RA,ADD1,MRPS15,DNAJC3,FBXO2,CACNA2D2,NRG2,DHX8,IL18,MORF4L2,SYTL4,BARD1,CA8,EPDR1,DAPK2,CALM2,WEE1,AP1M2,CYP2S1,CABP1,ALDH1A3,KLF3,TUBG1,SEMA3G,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,CYP4F3,PGF,DNM1L,LIMK1,AGFG2,SERPINB6,MRPS28,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,NUAK1,SOX9,MERTK,LMNA,ELF3,RAVER2,GNS,NEK2,NCAM1,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,MAL2,FBXO27,NDE1,DRP2,ARPC2,ZNF502,EGLN1,XDH,MTM1,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CCND1,RNF220,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,CYS1,SYNE2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,PKN1,TMA16,NUCB2,ETS1,ARHGEF40,GSTP1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,NPTXR,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,DCBLD1,UNKL,MYL9,SIGIRR,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,ANO4,TLN2,TRAM1,MYBL1,DDX59,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,PXDC1,MAFF,PRKAA2,BMF,ZCCHC24,HLA-F,UBASH3B,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,C9orf9,ABCC1,CYP26B1,CHSY3,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,EPN3,MAPKAPK2,H1F0,PVRL2,CSF1,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,AVPI1,NF2,UGP2,UPF3B,FOXM1,P3H2,ERBB2,CCDC68,CYP26A1,RAD23A,PLCG2,LHX6,SRR,EGLN3,DVL2,CTH,SIRT1,CPD,TIMP2,MBP,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,CMTM4,MAN2B2,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,DAP,GNE,SWI5,PSMD10,SELL,GABRG2,NKRF,CRABP2,SIRPA,PPP2R3A,CCDC92,BUB1,ABCD1,KLF9,FAIM,FAH,HMMR,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,FUCA1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PGRMC1,CLIP4,PPP2R3C,GUCD1,NDFIP1,UBE2C,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,TAP1,CCNB1,FAM101B,NCS1,CTGF,ELMO2,IQCE,PRICKLE3,ZFP36,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,PACSIN1,RCAN3,SMYD5,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,PBK,HSPA12A,CASP9,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,NKD1,FAM110C,SARAF,DHTKD1,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,PMPCB,DDB2,ZNF84,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,RASA1,STX3,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,DAB2IP,IFIT1,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,LINC01588,H2AFV,SP4,ZNF469,NIN,CMTM7,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,NR3C2,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,MPP1,PARP4,FURIN,C1GALT1C1,NUCB1,AMMECR1,CSTF2,PGM2L1,GRIN2D,GPER1,ARSB,NCAPG2,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,LTBP1,CASP3,NMRK1,FLYWCH2,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,KREMEN1,TSEN34,SH3KBP1,ABCD4,CHPF,C7orf49,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,POF1B,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,PTGFRN,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,ADIPOR1,RAP1GAP,CPPED1,GRN,PIFO,LRRFIP2,PEX6,SAMD9,PHLPP1,AIM1L,ZNF432,CA2,KCNN4,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,RNF113A,AMDHD1,GNAS,FECH,BCAR3,NUDT16,ONECUT1,PLPP3,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,PROM2,GAS2L1,SLC25A24,FAM92A1,SPC25,IL15,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,GCA,ZNF525,IGSF8,ERBB2IP,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,ANXA3,SORT1,FRMD6,POC1B,LRP4,ARMC7,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IRF2BPL,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,NR4A1,MBNL3,OGDHL,KLHL2,HLA-B,DHRS2,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 1.268e-06 | -13.58 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | MSigDB lists | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | 29 | 13 | 17758 | 1761 |
CALM2,PLCG1,PIK3AP1,STIM1,PLCG2,CALM1,PIK3R1,CALM3,PIK3CD,ITPR2,ITPR3,SYK,SH3KBP1 |
| 1.271e-06 | -13.58 | BOQUEST_STEM_CELL_DN | MSigDB lists | BOQUEST_STEM_CELL_DN | 210 | 44 | 17758 | 1761 |
ANXA3,ARAP3,KIAA1462,SSH1,HOXB7,IL15,HLA-F,ITGA6,CCDC68,F11R,MGST2,PHLDA1,IL18R1,TSPAN7,CARD10,MECOM,CARD8,RPS6KA2,GATA2,TSPAN6,LHX6,TACSTD2,TSPAN13,HLA-C,EPHB4,PTPRE,MAST4,MYRIP,SMAGP,ENPP4,MCTP1,SYBU,SPTLC2,CDK1,KLHL2,BCAR3,HLA-B,SLCO4A1,SWAP70,ETS2,PIK3C2B,IFIH1,ABCG1,DOCK9 |
| 1.279e-06 | -13.57 | MODULE_3 | MSigDB lists | MODULE_3 | 382 | 68 | 17758 | 1761 |
DLGAP5,HSPG2,EPAS1,NQO1,S100A11,FOXM1,IQGAP1,PTTG1,CCNB1,IER3,PLS3,CCND1,APOBEC3B,RCN1,PDGFA,BTG3,VAT1,F2R,CKS2,PLK1,SEC23A,CD55,CENPA,CDC20,ARHGDIB,LOXL2,CCNF,MCFD2,ITPR3,ALCAM,CDK1,CASP4,DPYSL3,MDK,PGF,PLK2,MAFF,GRN,ANXA3,ITGA6,GDF15,TOP2A,CTSC,CYR61,CALD1,PPP4R1,UBE2J1,SGK1,IGFBP2,CITED2,FADS2,ZWINT,PRSS23,PLAUR,MYBL2,GGH,KIF11,PSMA4,STEAP1,SWAP70,UAP1,PLOD2,RND3,LTBP2,CCNB2,UBE2C,PKIA,ACOT7 |
| 1.293e-06 | -13.56 | cellular response to fibroblast growth factor stimulus | biological process | GO:0044344 | 315 | 60 | 16441 | 1675 |
SPRED1,RUNX2,TNRC6C,PSME2,IQGAP1,RASA2,CALM3,NRG2,ERBB2,PSMD10,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,CTGF,SHC3,PTEN,FLRT3,PIK3CA,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,ITPR3,PSMA4,RASA1,IRS2,PLCG1,JAK1,FGFR2,PHLPP2,ITPR1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.299e-06 | -13.55 | Rho guanyl-nucleotide exchange factor activity | molecular function | GO:0005089 | 77 | 23 | 16491 | 1673 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,EPS8L2,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,DOCK9,ARHGEF4,FGD1,FARP2 |
| 1.303e-06 | -13.55 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2389 | 310 | 16441 | 1675 |
TXN,PPP4R4,SSH1,DNAJC3,RET,FBXO2,NRG2,PSME1,IL18,CCNB1,CARD10,GRM5,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,RGS3,IL31RA,PIK3CA,CRY2,TNIP1,ACVR1C,PBK,CASP9,AGO4,PRKAR2B,F12,RNF19B,POR,PIAS3,ENPP1,PLCG1,ANKRD6,PLK2,LIMK1,TRAF3IP1,NOD2,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,GAB1,CDKN1C,NUAK1,SOX9,RAB23,MECOM,TFAP4,CYR61,PAIP2B,DAPK1,MAP3K9,SORL1,MYDGF,NCAM1,MYLIP,PPP6R1,SOCS5,MMD,MFI2,CALM1,PYM1,EPHA1,PSMA4,RASA1,FAS,PRKAG2,SEMA4D,PELI2,FAM83D,AURKA,STK39,GDF11,MAP3K5,SERPINB1,XDH,SPRED1,DLGAP5,RPS6KA1,IQGAP1,CAST,PTTG1,PRKACA,CCND1,APLP2,ST5,DACT1,CDKN1B,DAB2IP,PDE4D,RASGEF1A,DLG3,CDKN2D,CAMSAP3,RIPK2,FZD4,CDCA2,SLC11A2,PKMYT1,SNX12,FZD7,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,SLC27A1,NRG1,RGS14,MAPK12,PCOLCE,NKX3-1,TNRC6C,SDC4,HERC5,PKN1,GSTP1,TIPRL,FGF19,SNTA1,DIRAS3,RNF128,CTSC,PTEN,CST3,BAX,MAPK11,ERBB3,CNOT6L,SPRY2,CRTAP,RASGRF1,PDGFC,RAPGEF2,NUB1,EIF5A2,GRIN1,FURIN,YES1,GPLD1,CDK5RAP1,TIMP3,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CPEB2,ESPL1,JARID2,CASP3,CAMKK1,CNOT8,EPHA4,ARFGEF1,NDRG2,NENF,VARS2,HDAC6,PDGFB,ERP29,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,PASK,DLG1,DUSP10,SLC39A10,RASGRP1,PLK1,CD55,USP18,ITCH,EZR,CDK1,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,LMTK3,SERPINE2,PPP1R2,RASA2,UBASH3B,DNAJB2,PDCL,CALM3,TEC,PHLPP1,FBLN1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,CCDC88A,MDFI,HMG20B,STRADB,PDE5A,EIF2AK1,RANBP9,CDK5R1,FECH,BCAR3,MAPKAPK2,PLPP3,CSF1,NFKBIA,JAK3,IFI6,TOB1,PROM2,USP43,CCNE2,AVPI1,NF2,UPF3B,IL15,FOXM1,PSME2,CTDSPL,TP53,ERBB2,EMP2,STIL,BCAP31,SYTL2,RAD23A,PDGFA,SVBP,KIF14,BCL6,TWIST1,EGLN3,F2R,CTDSP2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,TIMP2,AKT1,CDC20,ACO1,DUSP4,CD40,MAP3K6,DAG1,SOCS3,DNAJC10,IDE,PTPRJ,STK38,SPTBN5,EFNA5,PPP2R2D,ARFGEF3,PINK1,CPEB4,DAP,LRP4,PSMD10,GDF15,TGFBR1,TRIB2,PPP2R3A,SH2D4A,CD109,CARD8,ADORA1,BMP7,TRIM21,BUB1,IQGAP3,SYK,HES1,RHOA,PSMB4,PLAUR,GCLC,RGCC,PRICKLE1,COL7A1,MAPK8IP1,BANK1,SWAP70,SERPINA1,RAP2C,NMI,SPINT2,ARRB1,PPP2R3C,NDFIP1,UBE2C,HIPK3,PKIA |
| 1.308e-06 | -13.55 | GSE29618_BCELL_VS_PDC_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DN | 190 | 41 | 17758 | 1761 |
TXN,RUNX2,TRIP10,ST14,DNAJC3,PDIA3,NDUFA4,MGST2,NUCB2,SLC20A1,IL18R1,BCAP31,KIF5B,RPS6KA2,CTSC,DPYSL2,RIMS3,RRBP1,UBE2J1,RPN2,TAGLN2,MARCH2,LGMN,EGLN3,PTPRE,NAGA,CCDC88A,SEPHS1,SEC61B,CBX6,NPC2,LHFPL2,MYL12A,ATP13A2,PIAS3,MAPKAPK2,SCARB2,CORO1C,SH3BP4,IRF7,TBC1D4 |
| 1.308e-06 | -13.55 | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | 190 | 41 | 17758 | 1761 |
SLC35D2,SLC25A24,TTC39B,TBC1D1,UBASH3B,ITGA6,GNE,TAP1,DSE,HERC6,SEPP1,FAM101B,FAM46C,IL18R1,DTX3L,ADD3,KLF3,ANKRD12,SGK1,ABCD1,ALS2CL,GM2A,PQLC3,SNTB2,SYNE2,TTC7A,SESN1,ATP10D,ENDOD1,FAAH,MADD,NLRC5,IRF7,HS3ST3B1,MAP3K5,ARSB,TRAF5,IFIH1,F2RL1,ABCA1,XDH |
| 1.308e-06 | -13.55 | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | 190 | 41 | 17758 | 1761 |
GRN,TTC39B,UBASH3B,GNE,SDC4,TEX2,TRMT2B,DSE,NUCB2,FAM101B,FAM167A,IL18R1,LGALS3BP,RCN1,CCND1,FAM46A,CDH1,SGK1,SNX10,SCYL3,SPRY2,GM2A,MMD,ADCK3,STAT4,CORO2A,SNTB2,SYNE2,LITAF,ALCAM,ATP10D,HLA-B,BANK1,HPSE,FAAH,IRF7,HS3ST3B1,GEM,MAP3K5,TRAF5,XDH |
| 1.313e-06 | -13.54 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15921 | 1629 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CLDN4,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,MCCC2,HPS3,PQLC3,ELK1,NPHP3,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,PLOD2,RAB11FIP2,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,TIMP3,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,SOCS3,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,IFIT3,ANKRD29,G2E3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,SLC16A6,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.340e-06 | -13.52 | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | REACTOME pathways | R-HSA-983695 | 36 | 15 | 8202 | 867 |
CALM2,PLCG1,PIK3AP1,STIM1,PLCG2,ITPR1,CALM1,PIK3R1,CALM3,TRPC1,PIK3CD,ITPR2,ITPR3,SYK,SH3KBP1 |
| 1.345e-06 | -13.52 | MOHANKUMAR_TLX1_TARGETS_UP | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_UP | 390 | 69 | 17758 | 1761 |
UGP2,EPAS1,CPT2,FAM102B,MORF4L2,OAT,SLC20A1,CMTM6,IER3,WEE1,CYP1A1,SCNN1A,AP1M2,PAPSS1,SLC44A1,PHTF1,CNNM4,CDH3,RPN2,SULF2,SEMA3B,PLK1,GCA,SLC39A8,PLEKHO1,CDC20,HTATIP2,ICMT,ASB13,PTGFRN,CDK1,RBM47,CORO1C,PLK2,ADIPOR1,PIEZO1,GLA,CAPN1,FRMD4A,DCAF7,C6orf106,RAB6A,CRABP2,TFAP4,E2F7,FUT8,TFAP2A,SORL1,BUB1,ALDH3A2,ATP2B1,RBMS2,EPB41L5,ZWINT,LITAF,TXNDC11,GNAS,TIMP3,H1F0,PRCP,DHRS2,PGRMC1,ARRB1,PCDH19,ATP1B3,ZMIZ1,CCNB2,HOOK1,L1CAM |
| 1.357e-06 | -13.51 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 309 | 58 | 17758 | 1761 |
GRN,MAN2B2,LMO7,IER5L,SLC35D2,FRMD4A,PAPSS2,NUAK1,FRMD6,HLA-E,ZCCHC24,FAM134A,IL13RA1,OSR2,SEPP1,PHLDA1,LTBP3,LGALS3BP,LMNA,CHPF,IER3,GNS,SIPA1L2,NOV,FAM46A,CYR61,DOK4,RGS3,XYLT2,CST3,FAM63A,LIMCH1,ECE1,MYLIP,ATP2B1,IGDCC4,SULF2,CYP26B1,AMOTL2,ORAI2,HES1,SMARCA2,TIMP2,PRSS23,SAT1,COL7A1,NPC2,TP53INP2,GNAS,KCNMB4,MAP2,ANKRD6,NFKBIZ,HOXB13,GEM,TANC2,ABCA1,KLF7 |
| 1.362e-06 | -13.51 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | 177 | 39 | 17758 | 1761 |
CASP3,GNPDA1,FRMD6,TAP1,SELL,CD274,INTS8,FANCI,SCML1,DTX3L,LMO4,SLC44A1,CDH3,ALPK1,LGMN,LRP11,MAST4,CRTAP,LAMP3,PARP9,SUSD3,NFE2L3,SIRT1,TGIF1,RAPGEF2,C3orf52,CASP9,PTGER4,ATP1B1,DUSP4,PCTP,ADRBK2,CYB5A,STX3,PELI2,PLEKHG1,NETO2,IFIH1,MAFF |
| 1.380e-06 | -13.49 | regulation of GTPase activity | biological process | GO:0043087 | 553 | 92 | 16441 | 1675 |
ARHGAP11A,RALBP1,IQGAP1,EPHA4,ARFGEF1,RGS20,ERBB2,F11R,DENND2D,ARHGEF16,EPS8L2,ARHGEF10L,SIPA1L2,ST5,ACAP2,SH3BP1,ARHGEF37,RGS3,BCL6,DAB2IP,RP2,RASGEF1A,TIAM1,RASGRP1,DOCK4,ARHGDIB,CD40,DOCK5,ABR,ARHGEF26,ARHGAP35,PLEKHG6,ARHGEF19,CORO1C,MADD,SIPA1L1,PLEKHG1,AGFG2,EFNA5,RGS14,RAP1GAP,FGD1,DENND5B,ARFGEF3,ARHGEF3,ARAP3,DEPDC1,BVES,ARHGEF11,TBC1D1,ITGA6,RASA2,SBF1,ARHGEF40,RALGPS2,SNX18,RINL,LLGL2,RANBP1,FAM13B,TBCD,PRKG1,IQGAP3,ALS2CL,SPRY2,FARP2,RASGRF1,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,SPATA13,STMN3,SCRIB,EPHA1,GRTP1,RASA1,RASGRP2,GNAS,ARHGAP24,BCAR3,SEMA4D,SH3BP4,FGD6,ARRB1,TBC1D4,CPEB2,ARHGEF9,RAB3IL1,ARHGEF4,PROM2,DOCK9 |
| 1.389e-06 | -13.49 | Signaling by FGFR1 | REACTOME pathways | R-HSA-5654736 | 314 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.421e-06 | -13.46 | antigen processing and presentation of endogenous peptide antigen | biological process | GO:0002483 | 11 | 8 | 16441 | 1675 |
HLA-B,TAPBP,HLA-E,TAP1,ERAP1,HLA-C,HLA-A,ERAP2 |
| 1.439e-06 | -13.45 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 120 | 30 | 17758 | 1761 |
LAMP2,ANXA3,LASP1,PDGFC,CD55,PAPSS2,IGFBP6,LPGAT1,SOX9,EZR,SPR,SLC20A1,ERP29,CYB5A,STK17A,APLP2,ADD3,MLPH,H1F0,PLOD2,DPYSL2,P4HA2,TRIOBP,SH3BP4,STK39,FHL1,PLIN3,PDIA6,HSPB1,TIAM1 |
| 1.439e-06 | -13.45 | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | 184 | 40 | 17758 | 1761 |
REPS2,DLGAP5,FOXM1,ATP8A1,BLVRB,PTTG1,EPS8,ASB9,ABCG2,KIF23,HMGN3,TRIB2,CCNB1,DHRS3,HDAC9,CDKN2C,RPS6KA2,GNB5,RANBP1,SORL1,TUBG1,TSPAN13,MDFIC,TRAK2,HMMR,CORO2A,CDC20,CCNF,ENDOD1,BANK1,FAAH,INPP4B,ABCB1,EGFL7,SERPINB6,SERPINI1,WDR62,UBE2C,CCNB2,NXT2 |
| 1.439e-06 | -13.45 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 184 | 40 | 17758 | 1761 |
MTM1,ACACB,SORT1,PACSIN2,REPS2,EPAS1,NLRX1,TBC1D1,RPS6KA1,ZCCHC24,DCAF7,IL13RA1,FTH1,SAMD9,SNN,KBTBD11,IL18R1,DAPK2,DAPK1,TPST1,PIKFYVE,SYK,OSGIN1,MAP3K3,ORAI2,CD55,PLSCR1,AKT1,LPGAT1,C15orf39,FOS,POR,GALNT3,FUCA1,SLC6A6,MID1IP1,H1F0,GLA,ZMIZ1,JARID2 |
| 1.463e-06 | -13.44 | GCACCTT,MIR-18A,MIR-18B | MSigDB lists | GCACCTT,MIR-18A,MIR-18B | 114 | 29 | 17758 | 1761 |
PHF20L1,TRIM2,FRMD4A,GRHL2,NR3C1,GCLC,CTDSPL,C5orf30,TEX2,TRIB2,PTGFRN,ALCAM,PIAS3,BTG3,HSF2,ADD3,CTGF,CDK19,RAB11FIP2,ZNF367,XYLT2,SH3BP4,ZNF704,TRIOBP,IRF2,PACSIN1,GAB1,CCDC88A,SOCS5 |
| 1.509e-06 | -13.40 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | 191 | 41 | 17758 | 1761 |
SERPINE2,LGALS3,S100A11,GNPDA1,DAP,CDCA8,KIF23,LACTB2,REPS1,KCTD9,DAPK2,TOP2A,CDKN2C,CD9,BUB1,CDKN2D,CLIP2,SNX10,S100A13,LAMP2,PQLC3,S100A4,LITAF,ARHGDIB,CCNF,ANLN,ALCAM,CDK1,GABARAPL1,GNAS,CARHSP1,JAK1,TWSG1,CDCA5,DBI,AURKA,CTSA,CCNB2,E2F8,ACOT7,XDH |
| 1.569e-06 | -13.37 | GSE22886_NAIVE_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_DN | 198 | 42 | 17758 | 1761 |
GAA,EPAS1,NQO1,ST14,BLVRB,CTSZ,KCTD12,MGST2,DSE,VASH1,SIRPA,M6PR,ATP6V0B,PSMD1,SLC16A6,MITF,DAPK1,PTPRE,SYK,NAGA,CCDC88A,PPIF,LAMP2,DOCK4,GCA,ALDH2,GCLC,NFE2L1,ATP1B1,LHFPL2,ADRBK2,BCAR3,SLC6A6,RBM47,CORO1C,NR4A3,MDH1,GLA,ZMIZ1,PLIN3,SLC27A3,NRGN |
| 1.569e-06 | -13.37 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 198 | 42 | 17758 | 1761 |
CASP3,SERPINE2,LGALS3,CPT2,CD82,EPS8,SDC4,PPFIBP2,TP53,PSME1,NTAN1,SEPP1,GSTP1,AIP,BCAP31,TOP2A,GNB5,CDH1,KLF3,BAX,FXYD5,AHCY,OSTF1,S100A13,HMMR,SEC23A,CLCN3,CD55,ARHGDIB,FOS,GNA11,CASP4,ARF4,ENPP1,DDOST,HOXA9,NFKBIA,ABCB1,TLE1,SERPINB6,FHL1,TOB1 |
| 1.570e-06 | -13.36 | growth factor binding | molecular function | GO:0019838 | 118 | 30 | 16491 | 1673 |
LTBP1,SCN5A,SEC61B,SORT1,IGFBP6,ACVR1C,FURIN,ERBB2,TGFBR1,PDGFB,LTBP3,SRPX2,NRP2,CD109,PDGFA,NOV,CTGF,IGF1R,CYR61,ACVRL1,FGFR2,IL6ST,VASN,COL6A1,IGFBP2,LTBP2,ERBB3,ITGAV,S100A13,LIFR |
| 1.662e-06 | -13.31 | REACTOME_SIGNALLING_BY_NGF | MSigDB lists | REACTOME_SIGNALLING_BY_NGF | 212 | 44 | 17758 | 1761 |
CASP3,ARHGEF3,ARHGEF11,RPS6KA1,CALM3,ITPR2,PHLPP1,PRKACA,ARHGEF16,CALM2,RPS6KA2,ADRBK1,PTEN,SHC3,PIK3CA,CDKN1B,MAPK11,TIAM1,RASGRF1,RHOA,RIPK2,AKT1,NR4A1,PIK3R1,CALM1,CASP9,FURIN,PRKAR2B,DUSP4,ELK1,ITPR3,CDK1,ABR,IRS2,MAPKAPK2,PLCG1,NGFRAP1,NFKBIA,HDAC1,ARHGEF9,ARHGEF4,MAPK12,FGD1,PCSK5 |
| 1.664e-06 | -13.31 | ESC_J1_UP_LATE.V1_UP | MSigDB lists | ESC_J1_UP_LATE.V1_UP | 185 | 40 | 17758 | 1761 |
LMO7,PRSS8,SERPINE2,FXYD3,PDIA5,MORC4,SEPP1,PHLDA1,PARM1,CYP26A1,ST5,SESN3,RNF128,CTGF,CYR61,CTSC,FUT8,ENPP5,DRAM1,TNFRSF12A,TINAGL1,LGMN,CITED2,NAGA,TPCN1,MYO5B,SGCE,ARAP2,PCDH1,CD55,CAPN6,SLC39A8,PRICKLE1,LOXL2,IRS2,SHROOM3,P4HA2,WBSCR27,UNC5B,OCLN |
| 1.664e-06 | -13.31 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 185 | 40 | 17758 | 1761 |
BIN1,CCNI,SPRED1,SEMA6B,TRIM2,CEP70,ATP8A1,SLC1A3,TNFRSF19,TTYH3,NCS1,IGF1R,SNX18,IMPAD1,FJX1,DAB2IP,KLF9,ATP2B1,SMARCA2,TRIM8,TIMP2,ACVR1C,ZC3H11A,LPGAT1,SNTB2,PIK3R1,FNDC3A,ADRBK2,SP4,CDK5R1,NFIX,ENDOD1,PTPRJ,SLC4A4,PGM2L1,PCDH19,TMOD2,CPEB2,NR2C2,EGLN1 |
| 1.673e-06 | -13.30 | Developmental Biology | REACTOME pathways | R-HSA-1266738 | 710 | 114 | 8202 | 867 |
MYL9,SPRED1,SLC2A4,EPAS1,PSME2,RPS6KA1,IQGAP1,EPHA4,ERBB2,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,ARTN,SHC3,DPYSL2,DLG1,DUSP10,TRPC1,DAB2IP,NTN4,EPHB4,MYH14,SCN2A,DLG3,RASGEF1A,TIAM1,MED30,RASGRP1,SCN3A,FRS3,COL6A2,AKT1,ACVR1C,DRAP1,EZR,PRKCQ,DUSP4,ALCAM,MYL12A,DPYSL3,ARHGAP35,EPHA10,IRS2,PLCG1,PPP2R5A,JAK1,CDK19,LIMK1,KLF5,EFNA5,NRG1,SPTBN5,UNC5B,MYL12B,MAPK12,COL9A3,SCN5A,ARHGEF11,RASA2,CALM3,PSMD10,COL4A5,FGF19,EFNB1,NRP2,NEO1,COL6A1,MAPK11,ERBB3,CACNA1D,NCAM1,NCOA2,MED22,FARP2,DPYSL5,RASGRF1,HES1,ARHGEF28,RHOA,PSMB4,RGMB,SALL4,RAPGEF2,CALM1,PPARA,GRIN1,FURIN,YES1,EPHA1,RANBP9,PSMA4,CDK5R1,RASA1,CNTNAP1,NCOA3,ONECUT1,FGFR2,SEMA4D,ARRB1,PITPNA,GRIN2D,ITGAV,ARPC2,JAK3,SEMA3A,L1CAM,RGMA |
| 1.709e-06 | -13.28 | GNF2_MCM4 | MSigDB lists | GNF2_MCM4 | 53 | 18 | 17758 | 1761 |
HMMR,ZWINT,FOXM1,ASPM,CDC20,NDC80,CDCA8,KIF11,FANCI,TOP2A,KIF14,AURKA,BUB1,CCNB2,UBE2C,ESPL1,MELK,CKS2 |
| 1.710e-06 | -13.28 | PATIL_LIVER_CANCER | MSigDB lists | PATIL_LIVER_CANCER | 698 | 108 | 17758 | 1761 |
NF2,DLGAP5,NQO1,HDAC11,PTTG1,ARFGEF1,NUF2,BCAP31,SYTL2,RAD23A,CDKN2C,HSF2,ACAP2,UBE2T,IMPAD1,PLK4,TUBG1,VAT1,ACOX2,NOTCH3,SLC39A10,LRP11,ETV4,DVL2,LAMP2,CPD,PLK1,OSTM1,PBK,CDC20,HTATIP2,NUSAP1,LOXL2,PKMYT1,PTGFRN,TP53I3,CDK1,TYSND1,PRIM1,LRRC42,PLCG1,MID1IP1,PPP2R5A,DDOST,PEX2,RAB11FIP1,ZNF704,EIF4EBP2,GLA,C1orf43,E2F8,GAB1,CAPN1,RRAGD,GRN,GCLM,PARP12,HJURP,DCAF7,CDCA8,KIF23,PSMD10,GPSM2,INTS8,TTYH3,BEX2,LBR,SAC3D1,CD109,TOP2A,GNB5,MGAT4A,FAM63A,NEK2,ADAM15,BUB1,RFX5,MPHOSPH9,NCOA2,CRTAP,CCDC88A,HMMR,SYPL1,FADS2,ZWINT,LPGAT1,MBNL3,MYBL2,CCDC34,COL7A1,KIF11,PTPRF,ONECUT1,NCOA3,CDKN2AIPNL,H1F0,DCK,CDCA5,CTSA,DONSON,HMGA1,MAL2,PLOD3,NCAPG2,UBE2C,ESPL1,TOB1,RUSC1 |
| 1.733e-06 | -13.27 | Signaling by FGFR2 | REACTOME pathways | R-HSA-5654738 | 316 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.733e-06 | -13.27 | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | MSigDB lists | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | 34 | 14 | 17758 | 1761 |
MMP15,LASP1,SLC37A1,TJP3,AKT1,PVRL2,CDK16,DUSP10,ADIPOR1,CYB561,DDR1,POR,ARHGEF16,GPX4 |
| 1.734e-06 | -13.27 | response to hormone | biological process | GO:0009725 | 1003 | 148 | 16441 | 1675 |
CASP3,UGT8,NRG2,PSME1,PDGFB,SDC1,SPTB,CALM2,SESN3,PSMD1,CTGF,SHC3,FOSB,STEAP2,PIK3CA,ABCA2,AKR1B1,CLDN4,RASGRP1,THRB,CITED4,ACVR1C,CASP9,PRKAR2B,IDH1,POR,RHEB,PIAS3,MDK,ENPP1,MAP2,CAB39,EIF4EBP2,ADIPOR1,GAB1,NR2C2,RRAGD,PRKAA2,GRN,RASA2,CALM3,TFAP4,ITGA3,CA2,IGF1R,NCAM1,PAQR7,CALM1,STRADB,ELK1,PSMA4,RASA1,FAS,GNAS,FECH,MMP15,NCOA3,PRKAG2,AURKA,NR4A2,JAK3,RARG,GAS2L1,SPRED1,SLC2A4,SORBS1,NQO1,FOXM1,THRA,PSME2,ERBB2,PRKACA,PDGFA,CCND1,ATP6V0B,CDKN1B,GOT1,DAB2IP,RASGEF1A,NR2C1,FRS3,SIRT1,TIMP2,AKT1,PTPRU,PRKCQ,DAG1,SOCS3,IRS2,IDE,ATP1A1,JAK1,SLC27A1,NRG1,SPTBN5,LTA4H,NR3C2,ANXA3,NKX3-1,SORT1,PSMD10,ETS1,FGF19,HDAC9,PTEN,BMP7,CST3,TOX2,BAX,IGFBP2,ERBB3,KLF9,CITED2,NCOA2,MYO5A,GCNT1,RASGRF1,RHOA,PSMB4,NR3C1,GCLC,NR4A1,RAPGEF2,PIK3R1,GRIN1,PPARA,GGH,YES1,FOS,BBS2,BCAR1,GPLD1,CTSL,PITX2,TIMP3,PLOD2,NR1D2,FGFR2,CTSV,NR4A3,GRIN2D,HOXB13,GPER1,PLOD3,ARSB,TBC1D4,CPEB2,ABCG1 |
| 1.735e-06 | -13.26 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 121 | 30 | 17758 | 1761 |
GFPT1,SMARCA2,TGIF1,MBP,ELK3,TRIM2,RUNX2,SSH1,TSC22D3,CORO2A,EPS8,LITAF,UTRN,SNTB1,SEPP1,CMTM6,CARD8,SCNN1A,PIK3CA,BCL6,LIMCH1,PIM1,MYLIP,MAST4,AHR,ALDH3A2,RASGRP1,ERAP2,KLF7,TRAK2 |
| 1.738e-06 | -13.26 | GSE20715_0H_VS_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_UP | 192 | 41 | 17758 | 1761 |
TTC8,PARP12,VANGL1,PPFIBP2,PKP2,FAM198B,GRK6,GPSM2,TNFRSF19,PDGFB,ANO1,SH3KBP1,LMNA,CDKN2C,MDM1,DACT1,SIVA1,AKR1B1,TAGLN2,RCAN3,MYLIP,DGKG,S100A13,SEC61B,IFITM3,SEPT6,MPP1,RAB38,EPHA1,DCTN6,AMZ2,GPRC5B,SEMA4D,CSNK1G1,CSF1,PRKCDBP,MRPS28,UNC5B,FZD5,SERPINB1,GAB1 |
| 1.738e-06 | -13.26 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | 192 | 41 | 17758 | 1761 |
SPC25,CEP70,DEPDC1,DLGAP5,C5orf30,MPP5,INTS8,ETS1,REPS1,APPBP2,E2F7,NEK2,ATRNL1,DLG3,RNF26,WBP5,METAP2,TRAK2,PLK1,FADS2,SSH3,ALDH2,AKT1,PBK,MBNL3,PDE5A,EZR,NUSAP1,LRRC1,C3orf58,CYB5A,UEVLD,ZNF704,NETO2,AURKA,FAM117A,ETAA1,REEP4,TOB1,E2F8,ZBTB33 |
| 1.738e-06 | -13.26 | WELCSH_BRCA1_TARGETS_UP | MSigDB lists | WELCSH_BRCA1_TARGETS_UP | 192 | 41 | 17758 | 1761 |
ADD1,IQGAP1,HEXB,PBX3,NDUFA4,HMGN3,RAB6A,SEPP1,TOP2A,EPCAM,KIF5B,ADD3,CD9,TMBIM6,WWP1,ALDH7A1,CITED2,NDUFA12,TRAM1,CKS2,HMMR,SEC23A,NR3C1,MICB,NPC2,IDH1,KIF11,ALCAM,MYL12A,CDK1,GALNT3,JAK1,DDOST,H1F0,KCNK1,PRCP,NAT1,PGRMC1,HDAC1,ARF6,SERPINB1 |
| 1.741e-06 | -13.26 | regulation of protein metabolic process | biological process | GO:0051246 | 2557 | 328 | 16441 | 1675 |
TXN,PPP4R4,SSH1,DNAJC3,RET,FBXO2,NRG2,PSME1,IL18,CCNB1,BARD1,CARD10,GRM5,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,RGS3,IL31RA,PIK3CA,CRY2,TIPARP,TNIP1,ACVR1C,PBK,CASP9,AGO4,PRKAR2B,F12,RNF19B,POR,PIAS3,ENPP1,PLCG1,ANKRD6,PLK2,LIMK1,TRAF3IP1,NKD1,NOD2,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,GAB1,CDKN1C,GGA1,NUAK1,SOX9,RAB23,MECOM,TFAP4,CYR61,PAIP2B,DAPK1,MAP3K9,SORL1,MYDGF,NCAM1,MYLIP,PPP6R1,SOCS5,MMD,MFI2,CALM1,PYM1,EPHA1,PSMA4,RASA1,FAS,PRKAG2,SEMA4D,PELI2,FAM83D,AURKA,STK39,GDF11,MAP3K5,SERPINB1,XDH,SPRED1,DLGAP5,INPP5D,RPS6KA1,IQGAP1,CAST,PTTG1,PRKACA,APC2,CCND1,APLP2,ST5,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,RASGEF1A,CDKN2D,CAMSAP3,RIPK2,FZD4,CDCA2,PRKCQ,SLC11A2,PKMYT1,SNX12,FZD7,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,SLC27A1,NRG1,RGS14,MAPK12,PCOLCE,NKX3-1,TNRC6C,SDC4,HERC5,CTSZ,PKN1,GSTP1,TIPRL,FGF19,SNTA1,DIRAS3,RNF128,CTSC,PTEN,CST3,BAX,MAPK11,ERBB3,CNOT6L,SPRY2,CRTAP,RASGRF1,PDGFC,RAPGEF2,NUB1,EIF5A2,GRIN1,FURIN,YES1,GPLD1,CDK5RAP1,TIMP3,FGFR2,ACVRL1,RYK,GRIN2D,ITGAV,GPER1,CENPE,LRRK1,FZD5,CPEB2,ESPL1,JARID2,SIGIRR,CASP3,CAMKK1,CNOT8,CUL4B,EPHA4,ARFGEF1,NDRG2,NENF,VARS2,HDAC6,PDGFB,ERP29,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,PASK,DLG1,DUSP10,SLC39A10,RASGRP1,PLK1,CD55,ITCH,USP18,EZR,CDK1,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,LMTK3,PPP1R2,SERPINE2,RASA2,UBASH3B,DNAJB2,ASB9,PDCL,CALM3,TEC,PHLPP1,FBLN1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,CCDC88A,MDFI,HMG20B,STRADB,PDE5A,EIF2AK1,RANBP9,CDK5R1,FECH,BCAR3,MAPKAPK2,PLPP3,CSF1,NFKBIA,CTSA,YOD1,JAK3,TOB1,IFI6,PROM2,USP43,CCNE2,AVPI1,NF2,UPF3B,IL15,FOXM1,PSME2,CTDSPL,TP53,ERBB2,EMP2,STIL,BCAP31,SYTL2,RAD23A,IER3,PDGFA,SVBP,KIF14,BCL6,TWIST1,ECE1,EGLN3,F2R,CTDSP2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,TIMP2,ERLEC1,AKT1,CDC20,ACO1,DUSP4,CD40,MAP3K6,DAG1,SOCS3,DNAJC10,IDE,PTPRJ,STK38,SPTBN5,EFNA5,PPP2R2D,ARFGEF3,PINK1,CPEB4,DAP,LRP4,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,CARD8,ADORA1,BMP7,UBE2J1,TRIM21,BUB1,IQGAP3,SYK,HES1,RHOA,PSMB4,PLAUR,GCLC,RGCC,PRICKLE1,COL7A1,MAPK8IP1,BANK1,SWAP70,SERPINA1,SPINT2,RAP2C,NMI,ARRB1,PPP2R3C,NDFIP1,UBE2C,HIPK3,PKIA |
| 1.783e-06 | -13.24 | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | MSigDB lists | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | 103 | 27 | 17758 | 1761 |
MYO5B,ANXA3,TRIM2,KLK10,PINK1,TACC1,SOX9,KLK6,ARHGDIB,SAMD9,B4GALT4,AIF1L,SLC20A1,SYTL2,ELF3,MUC16,CTGF,GRHL1,ALDH1A3,RAB11FIP1,DAPK1,FUT1,INPP4B,VSIG10,MYH14,ERBB3,C10orf54 |
| 1.783e-06 | -13.24 | SUNG_METASTASIS_STROMA_UP | MSigDB lists | SUNG_METASTASIS_STROMA_UP | 103 | 27 | 17758 | 1761 |
GAA,CD55,PINK1,HSPG2,XYLT1,ETV5,EPS8,SDC4,FURIN,PDIA5,CRABP2,PTGFRN,ALCAM,COL12A1,TIMP3,KCNK1,PLOD2,LMO4,PLK2,UACA,RFX5,FHL1,CLIP2,IFI6,CTDSP2,CPEB2,SOCS5 |
| 1.826e-06 | -13.21 | MODULE_11 | MSigDB lists | MODULE_11 | 516 | 85 | 17758 | 1761 |
TRIM2,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,APC2,CARD10,CCND1,CABP1,LMO4,BCL6,IFIT1,BTBD3,SGCE,MBP,CBX6,KLK6,LDB2,ALCAM,FZD7,DPYSL3,TRIM9,HLF,GPRC5B,MAP2,KCNK1,TLE1,SERPINI1,ITPKA,NRGN,ABCA1,BIN1,WASF3,COL9A3,CDH22,ENO2,ATP9A,ITGA6,DNAJB2,ETV5,SOX9,CALB2,GABRG2,CYB561,CNTNAP2,SLC1A3,SEPP1,TSPAN7,NEO1,CA2,GNB5,RIMS3,SGK1,ALDH7A1,IGFBP2,ERBB3,NCAM1,GAD1,RIMS2,ATP2B1,IGSF3,FADS2,MMD,GCLC,BCL9,GRIN1,TCF7,FOS,TIMP3,SERPINA1,FGFR2,SCG2,ITGA7,ITPR1,TCEAL4,CDK18,STK39,L1CAM,PKIA,SNPH,ARHGEF4 |
| 1.847e-06 | -13.20 | signal transduction by protein phosphorylation | biological process | GO:0023014 | 413 | 73 | 16441 | 1675 |
SPRED1,RPS6KA1,PSME2,RET,ERBB2,NRG2,IL18,PSME1,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,DOK4,IL31RA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,MAP3K3,RIPK2,ACVR1C,PTGER4,DUSP4,MAP3K6,IRS2,JAK1,STK26,NOD2,CAB39,NRG1,SPTBN5,GAB1,MAPK12,RASA2,SOX9,PSMD10,CALM3,TGFBR1,PKN1,TNFRSF19,FGF19,MAP3K9,MDFIC,MAPK11,ERBB3,IQGAP3,NCAM1,SYK,MDFI,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,STRADB,ELK1,FOS,PSMA4,MAPK8IP1,RASA1,MAPKAPK2,SCG2,FGFR2,ACVRL1,STK39,GRIN2D,ITGAV,MAP3K5,JAK3 |
| 1.856e-06 | -13.20 | plasma membrane region | cellular component | GO:0098590 | 906 | 134 | 17570 | 1756 |
EPHA4,SYTL4,HDAC6,PJA2,PDGFB,NCS1,EPCAM,CABP1,DLG1,CLDN4,TRPC1,TACSTD2,RP2,PACSIN1,MYRIP,SGCE,EZR,ARF4,ENPP1,KCNK1,ATP7B,NOD2,PRKCDBP,PIEZO1,ARF6,LZTS1,DDX58,SCN5A,BVES,ITGA6,CNTNAP2,NCKAP1,SLC1A3,DHRS3,ANO1,CA2,ITGA3,IGF1R,ZNRF2,FLRT3,KCNN4,SLC12A2,RIMS2,GPR161,ABCC1,EPB41L5,SPATA13,SCRIB,ANTXR1,STX3,RASGRP2,GABRD,SLC4A4,TJP3,TMEM30A,PHLPP2,STK39,MAL2,PLD1,ATP1B3,SHROOM2,RUSC1,EHD1,PROM2,SPRED1,NF2,TCTN2,ST14,ERBB2,KCTD12,EMP2,PRKACA,APC2,EPS8L2,SCNN1A,CDH1,CNNM4,PDE4D,RAB27B,DLG3,F2R,CYS1,SYNE2,UTRN,SLC11A2,ATP1B1,ERBB2IP,DAG1,GABARAPL1,DUOX1,PTPRJ,ATP1A1,SHROOM3,STK26,CORO1C,SIPA1L1,SPTBN5,NRG1,EFNA5,SLC27A1,RGS14,TTC8,PACSIN2,LRP4,EPS8,GABRG2,SRPX2,FZD6,SNTA1,ADORA1,ANKS1B,PTEN,CD9,ATP8B1,IGFBP2,ERBB3,SPRY2,AMOTL2,DLGAP1,RHOA,CRB3,RAPGEF2,PLAUR,GRIN1,AIF1L,BBS2,ARRB1,GRIN2D,GPER1,ITGAV,L1CAM,OCLN,CYBRD1,ARHGEF4 |
| 1.867e-06 | -13.19 | response to stress | biological process | GO:0006950 | 3601 | 443 | 16441 | 1675 |
TXN,ADD1,LGR4,AK7,TSC22D3,DNAJC3,RET,TAP1,FBXO2,NRG2,PSME1,IL18,MORF4L2,CAMK1D,CCNB1,VASH1,BARD1,CALM2,WEE1,CYP1A1,PSMD1,CTGF,UBE2T,STIM1,ELMO2,ZFP36,IL31RA,PIK3CA,AOX1,IRF2,CRY2,PIK3CD,MANF,APOBEC3G,LAMP2,TNIP1,SPATA18,CASP9,SLC35C1,AGO4,PRKAR2B,LOXL2,PIF1,F12,RNF19B,ARF4,PLCG1,LIMK1,NOD2,HDAC1,SERPINB6,NFKBIZ,HSPB1,F2RL1,GAB1,DDX58,NUAK1,THEMIS2,ITGA6,HLA-E,DGKQ,RAB23,KIF23,SLC1A3,MERTK,TNFRSF19,PSIP1,LMNA,ATG4A,MECOM,ELF3,TFAP4,ITGA3,CYR61,RIMS3,RPL39,VASN,FLRT3,FAM13B,TPST1,DAPK1,MAP3K9,PRKG1,ALPK1,MYDGF,PANX2,NCAM1,ULBP2,DGKG,NDUFA12,NUP85,GFPT1,REC8,DDB2,PRODH,MICB,CALM1,ANO6,ERO1A,ELK1,GNA11,PSMA4,RASA1,FAS,DGKH,PTPRF,PELI2,MATN2,ITPR1,RAET1L,MDH1,NR4A2,STK39,ARPC2,MAP3K5,IFIH1,NUP58,TMEM173,EGLN1,EHD1,DOCK9,PLA2G4A,SPRED1,SLC2A4,NQO1,PAPSS2,NLRX1,THRA,INPP5D,RPS6KA1,ACTR8,PTTG1,BCL2L1,SNN,PRKACA,DDR1,APOBEC3B,CCND1,NOV,SP100,CDKN1B,DAB2IP,IFIT1,LRP11,RASGEF1A,LGMN,CDKN2D,ATG4D,GPX4,MX1,ENPP4,SEC61B,RIPK2,APOBEC3D,PRKCQ,SLC11A2,ATP1B1,RAD17,XRCC6BP1,ITPR3,FZD7,IRS2,ALDH3B1,JAK1,DDOST,STK26,WFS1,AXL,SLC27A1,NRG1,RGS14,MAPK12,TNRC6C,NKX3-1,HABP4,SDC4,PDIA3,HERC5,APOBEC3H,FBXO6,PKN1,SEPP1,ETS1,GSTP1,TIPRL,FGF19,LGALS3BP,HLA-A,PDIA4,CTNNBIP1,DTX3L,E2F7,CXCL16,FAM111A,PTEN,CST3,SGK3,CD9,BAX,ADAM15,TMBIM6,MAPK11,ERBB3,CITED2,CNPY3,TRIM62,PARP9,RASGRF1,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,PARP4,C1GALT1C1,FBXO9,YES1,FOS,KIF11,TIMP3,HCP5,PLOD2,FGFR2,ACVRL1,SYT7,DBI,NR4A3,OSER1,GRIN2D,ITGAV,GPER1,HMGA1,CENPE,WDR45B,CPEB2,MELK,MYL9,SIGIRR,CASP3,EPAS1,CUL4B,LMCD1,DNAJB11,F11R,ITPR2,TP53I11,HDAC6,PDGFB,SDC1,TRIM68,SPTB,FANCI,RPS6KA2,SHC3,AKR1B1,DUSP10,SCARA3,RASGRP1,CYP1B1,PLK1,NLRP4,CD55,KCNIP3,TRIM8,ITCH,USP18,NFE2L1,CR2,KLK6,PRKRA,IDH1,SESN1,CDK1,OPTN,DPYSL3,EDNRA,KDM4D,MDK,NEIL1,ARHGEF19,KCNMB4,HPSE,WIPI1,CAB39,MAFF,NR2C2,RRAGD,PRKAA2,LGALS3,SERPINE2,DNAJB2,HLA-F,RASA2,ETV5,CALM3,NCKAP1,TEC,PHLPP1,FBLN1,ANO1,CA2,GATA2,KCNN4,SELK,AHCY,MDFIC,HLA-C,WNT3A,MDFI,ELK3,OXR1,HMG20B,STRADB,PDE5A,VWA1,SCRIB,EIF2AK1,PDK3,IFIT3,RASGRP2,GNAS,MAPKAPK2,PHLPP2,CSF1,CGREF1,CDCA5,NFKBIA,NLRC5,YOD1,ATP1B3,PLD1,JAK3,APOL2,IFI6,USP43,GAS2L1,SLC25A24,FOXM1,IL15,PSME2,XYLT1,TMX4,PDIA5,TP53,ERBB2,COL18A1,IL27RA,SLC7A2,IER3,RAD23A,PDGFA,CYP4F11,PLCG2,BCL6,CDH3,TWIST1,EPB41L4B,OAS3,SCN2A,LMAN1,EGLN3,F2R,PDIA6,CTDSP2,FRS3,CTH,PPIF,SIRT1,ERLEC1,AKT1,PTGER4,DUSP4,CD40,FANCE,MYL12A,MAP3K6,CASP4,SOCS3,JADE1,DNAJC10,DUOX1,ABHD12,PTK7,IRF7,SPTBN5,LTA4H,ABCA1,ANXA3,GCLM,PINK1,CPEB4,CD63,DAP,SWI5,PSMD10,SELL,TGFBR1,DNAJB9,SIRPA,FZD6,HDAC9,IL17RB,TOP2A,ADORA1,ADRBK1,BMP7,UBE2J1,TFAP2A,SGK1,TRIM21,SYK,ATP2B1,RHOA,PSMB4,IFITM3,PLAUR,NR4A1,GCLC,AMFR,PPARA,RGCC,TXNDC11,BCAR1,MAPK8IP1,DGKE,CD83,CTSL,ARHGAP24,HLA-B,SERPINA1,SCG2,DHRS2,PRCP,CTSV,NMI,DTX4,ARRB1,HOXB13,ICOSLG,PTGES,L1CAM |
| 1.917e-06 | -13.16 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7530 | 836 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,MRPS15,AASS,RET,CACNA2D2,DHX8,FAM102B,DPP8,BARD1,LTBP3,ZNF275,GRM5,DAPK2,MUC4,KIAA1107,UBE2T,CYP2S1,ALDH1A3,KLF3,CRY2,SEMA3G,TINAGL1,PIK3CD,RNF26,TIAM1,TIPARP,MGAT5,APOBEC3G,DNAAF3,NWD1,SMARCA2,TNIP1,CDA,LOXL2,CYP4F3,COL12A1,ABR,ARF4,PLCG1,CARHSP1,DNM1L,ANKRD6,ATP7B,LIMK1,NOD2,RELL1,GAB1,SCN5A,NFKBIE,ALDH6A1,FAM169A,GGA1,ITGA6,SOX9,SLC36A4,FAM21C,TTYH3,LMNA,RAVER2,ELF3,ATG4A,MARCH8,FRY,FAM189A1,MEGF8,FLRT3,NEK2,PCYOX1,MAP3K9,ZMYM1,NCAM1,DGKG,NUP85,HPS3,SLC37A1,KIF20A,STAT4,NPHP3,SPTLC2,PCTP,SFXN5,GNA11,STK17A,DHX32,PTPRF,CACHD1,SCARB2,NCOA3,SLC4A4,ETS2,SEMA4D,ITPR1,S100A5,CLMN,AURKA,GDF11,FBXO27,ZNF502,TMEM173,DOCK9,MTM1,TPRN,PAPSS2,GALNT12,PKP2,PRSS22,NUF2,IL13RA1,GRK6,APC2,ZNF385B,APPBP2,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,SP100,DACT1,XYLT2,ENPP5,RTKN2,RASGEF1A,DLG3,SCN3A,MX1,CAMSAP3,SSH3,SEC61B,RIPK2,SYNE2,SAT1,ZNF618,COX20,IRS2,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,SLC25A30,ISOC1,TTC8,CTHRC1,TNRC6C,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,NEO1,PDIA4,ADD3,IGSF9,SLC27A6,ANKS1B,CTSC,CALD1,MGAT4A,CST3,FAM20B,BAX,ZFAND4,PLEKHF1,FAM102A,ADAM15,WWP1,SGCB,CRTAP,PARP9,ACBD5,AMOTL2,PVRL4,ADAMTS2,PLSCR1,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,NUB1,MRS2,CXorf57,MYEOV,SNTB1,CRISPLD2,CNTNAP1,PITX2,PLOD2,ACVRL1,PPM1H,CENPE,ITGAV,OSR1,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,PPM1J,CNOT8,EPHA4,ARFGEF1,NDC80,LMCD1,TEX2,MGAT5B,ITPR2,PDGFB,SPTB,CPNE2,RPS6KA2,SHC3,MKRN3,ELF5,TMEM143,ABCA2,DUSP10,ANO4,TLN2,MYBL1,NEB,CCDC38,ZNF462,PLK1,THRB,CD55,CELSR2,STAU2,NFE2L1,EZR,CR2,KLK6,IDH1,LHFPL2,DZIP1L,OPTN,KDM4D,TRIM9,PLEKHG6,MFAP3L,TMEM164,PLCH1,HS6ST1,KLF12,MAP2,HOXA9,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,GLCCI1,PRKAA2,RUNX2,HJURP,HLA-F,ZCCHC24,RASA2,CNTNAP2,NCKAP1,B4GALT4,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,RINL,FRAS1,EXOC8,MDFIC,FAR2,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,DPYSL5,PCDH1,TESK1,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,ITGA7,SLC2A6,LTBP2,ZDBF2,SEMA3A,RNF146,USP43,NF2,UGP2,UPF3B,FOXM1,CTDSPL,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,STIL,CYP26A1,SYTL2,TTC21B,PLK4,CDH3,VAT1,OAS3,SCN2A,LMAN1,CTDSP2,SULF2,CLCN3,TMTC1,MBP,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,ATP13A2,TAPBP,DUOX1,ATP1A1,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,ST3GAL1,ZNF701,MAN2B2,ZMAT1,BIN1,CMAS,COL9A3,GOLIM4,CDH22,KLHL13,MACC1,RUSC2,GNE,SELL,PSMD10,GTF3A,NKRF,DSE,SLC9A2,PPP2R3A,NRP2,FZD6,CD109,CCDC92,FOXP2,CDK16,BUB1,SYK,ATP2B1,GCNT1,IGDCC4,NFE2L3,HMMR,DLGAP1,HES1,RHOA,GUSB,PLAUR,STMN3,MAML2,COL7A1,FNDC3A,RNPEP,BCAR1,BSDC1,DGKE,CD83,SCRN2,SERPINA1,FAT4,CDCA7L,TMC5,CLIP4,PPP2R3C,SH3BGRL2,HIPK3,GOLGB1,DIS3L,LAMP1,SUN1,GAA,SLC35D2,PPP4R4,TTC39B,HSPG2,TMEM41B,ATP8A1,TSC22D3,PPFIBP2,PLXNA1,VASH1,PJA2,SLC9A7,NCS1,CYP1A1,SESN3,ZNF823,ELMO2,STIM1,OSBPL3,PRICKLE3,IQCE,FOSB,IL31RA,AOX1,PIK3CA,STEAP2,ATRNL1,IRF2,MTMR11,PACSIN1,ORAI2,LOC81691,SGCE,TMEM68,HSPA12A,SLC35C1,KIF13A,TNS1,GALNT7,LDB2,CCNF,ZFAND5,SLC25A5,TP53I3,POR,ARHGEF26,AHRR,RBM47,PLK2,GNPTAB,LRIG1,NKD1,BMP1,PRDM5,SERPINI1,TANC2,UNC5B,WBSCR27,TRAF5,LZTS1,FGD1,SEMA6B,MRC2,CDK17,FRMD4A,CDKN1C,DGKQ,C6orf106,ISYNA1,TNFRSF19,BMP2K,KIAA1161,MECOM,DOPEY2,SNX18,DAPK1,OPN3,PRKG1,TMEM51,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,GPR161,IGSF3,EPB41L5,DDB2,PRODH,MFI2,TBC1D8B,LPGAT1,AMER1,ANO6,VEZT,FAM133B,ATP8B3,ANTXR1,RASA1,STX3,GABRD,AP1AR,SLCO4A1,TJP3,FAAH,ISM1,PELI2,MATN2,SLC4A3,AGBL5,SFMBT1,PCDH19,NR4A2,PLIN3,MAP3K5,IFIH1,EHD1,FRMPD3,SPRED1,SLC2A4,TCTN2,REPS2,ARMCX3,NLRX1,IQGAP1,RPS6KA1,CCDC110,ATP2C2,CD274,DDR1,MNS1,ZFYVE9,EPS8L2,APLP2,ZNF75D,ACAP2,TRANK1,CNNM4,DAB2IP,PDE4D,EPHB4,LGMN,PHKA2,SULT2B1,NR2C1,DOCK4,COG2,CAPN6,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PRKCQ,PKMYT1,C15orf39,ITPR3,TRIQK,ATP10D,ZNF469,FZD7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,CCDC149,TRIOBP,NRG1,KLF5,MLKL,HS3ST3B1,SLC27A3,NR3C2,COBL,DENND5B,WASF3,HAPLN3,ATP9A,CENPI,CCNJL,HERC5,CYB561,DNAH3,TEAD3,HLA-A,LGALS3BP,SLC25A36,RASSF8,AKIRIN1,RNF128,PHF7,PTEN,FUT8,SGK3,CD9,ERBB3,CNOT6L,SPRY2,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ARAP2,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,LRRC1,GRTP1,ARSK,KIF11,GPLD1,MAMDC4,FGFR2,TBX18,ABCB1,ERAP1,CSTF2,PGM2L1,GRIN2D,ETAA1,FZD5,WDR62,NCAPG2,ARSB,ESPL1,JARID2,RGMA,EXPH5,LTBP1,CASP3,CPT2,VARS2,MPP5,DNER,CACNB4,ERP29,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,ZFYVE16,SIPA1L2,LRRC6,GRHL1,CEP78,ANKFN1,ANKRD12,AKR1B1,RAB20,CTTN,MYH14,SLC39A10,PTPRE,MYRIP,USP18,RGAG1,ARHGDIB,ROR1,ADRBK2,EDNRA,MAN2A2,ARHGEF19,GPRC5B,HPSE,KCNK1,MADD,SP6,LEMD1,CAPN1,PCSK5,ARAP3,SERPINE2,LRRFIP2,PEX6,BVES,PYROXD2,SAMD9,FAM81A,ADAMTSL4,OTUD1,B3GALNT1,ZNF432,AIM1L,KCNN4,COL6A1,LIMCH1,C10orf54,RFX5,HLA-C,SIMC1,LRIF1,SLC12A2,ALS2CL,ELK3,PODXL2,OXR1,GYLTL1B,HMG20B,RNF113A,HEATR5A,PDIK1L,RANBP9,SOX13,GLCE,GNAS,BCAR3,XKRX,ONECUT1,SLC6A6,UTP14C,ALPK3,RHOBTB2,DONSON,SHROOM2,JAK3,COL16A1,SNX30,PROM2,KLF7,CCNE2,LMO7,GAS2L1,LZTFL1,NCKAP5,SLC25A24,COL18A1,MRAS,TDRKH,OSR2,ARHGEF16,KCTD9,LRRC45,SLC25A48,SS18,ZNF687,SETDB2,CYP4F11,FRYL,ECE1,FRS3,SEPHS1,PTPRU,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,SOCS3,ARHGAP35,BHLHB9,PEX2,TLE1,SPTBN5,REEP4,ABCA1,LIFR,ANXA3,FBLIM1,TSPAN15,POC1B,FRMD6,LRP4,FAM134A,MIER3,TGFBR1,NOTUM,INTS8,POMGNT1,SBF1,FAM167A,HMGXB4,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,MLPH,LLGL2,TOX2,RRBP1,GALNS,KIAA0319,ARVCF,IQGAP3,CLIP2,MYO5A,PGM1,SYPL1,PHF20L1,SUN2,RC3H2,SYBU,OGDHL,TTC7A,RUNX3,TCEAL8,LEPR,KLHL2,ARHGAP24,HLA-B,SWAP70,PRCP,HNRNPH2,DHRS2,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,L1CAM,AHR,ABCG1,CD33 |
| 1.917e-06 | -13.16 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7530 | 836 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,MRPS15,AASS,RET,CACNA2D2,DHX8,FAM102B,DPP8,BARD1,LTBP3,ZNF275,GRM5,DAPK2,MUC4,KIAA1107,UBE2T,CYP2S1,ALDH1A3,KLF3,CRY2,SEMA3G,TINAGL1,PIK3CD,RNF26,TIAM1,TIPARP,MGAT5,APOBEC3G,DNAAF3,NWD1,SMARCA2,TNIP1,CDA,LOXL2,CYP4F3,COL12A1,ABR,ARF4,PLCG1,CARHSP1,DNM1L,ANKRD6,ATP7B,LIMK1,NOD2,RELL1,GAB1,SCN5A,NFKBIE,ALDH6A1,FAM169A,GGA1,ITGA6,SOX9,SLC36A4,FAM21C,TTYH3,LMNA,RAVER2,ELF3,ATG4A,MARCH8,FRY,FAM189A1,MEGF8,FLRT3,NEK2,PCYOX1,MAP3K9,ZMYM1,NCAM1,DGKG,NUP85,HPS3,SLC37A1,KIF20A,STAT4,NPHP3,SPTLC2,PCTP,SFXN5,GNA11,STK17A,DHX32,PTPRF,CACHD1,SCARB2,NCOA3,SLC4A4,ETS2,SEMA4D,ITPR1,S100A5,CLMN,AURKA,GDF11,FBXO27,ZNF502,TMEM173,DOCK9,MTM1,TPRN,PAPSS2,GALNT12,PKP2,PRSS22,NUF2,IL13RA1,GRK6,APC2,ZNF385B,APPBP2,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,SP100,DACT1,XYLT2,ENPP5,RTKN2,RASGEF1A,DLG3,SCN3A,MX1,CAMSAP3,SSH3,SEC61B,RIPK2,SYNE2,SAT1,ZNF618,COX20,IRS2,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,PNPLA6,SLC25A30,ISOC1,TTC8,CTHRC1,TNRC6C,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,NEO1,PDIA4,ADD3,IGSF9,SLC27A6,ANKS1B,CTSC,CALD1,MGAT4A,CST3,FAM20B,BAX,ZFAND4,PLEKHF1,FAM102A,ADAM15,WWP1,SGCB,CRTAP,PARP9,ACBD5,AMOTL2,PVRL4,ADAMTS2,PLSCR1,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,NUB1,MRS2,CXorf57,MYEOV,SNTB1,CRISPLD2,CNTNAP1,PITX2,PLOD2,ACVRL1,PPM1H,CENPE,ITGAV,OSR1,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,PPM1J,CNOT8,EPHA4,ARFGEF1,NDC80,LMCD1,TEX2,MGAT5B,ITPR2,PDGFB,SPTB,CPNE2,RPS6KA2,SHC3,MKRN3,ELF5,TMEM143,ABCA2,DUSP10,ANO4,TLN2,MYBL1,NEB,CCDC38,ZNF462,PLK1,THRB,CD55,CELSR2,STAU2,NFE2L1,EZR,CR2,KLK6,IDH1,LHFPL2,DZIP1L,OPTN,KDM4D,TRIM9,PLEKHG6,MFAP3L,TMEM164,PLCH1,HS6ST1,KLF12,MAP2,HOXA9,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,GLCCI1,PRKAA2,RUNX2,HJURP,HLA-F,ZCCHC24,RASA2,CNTNAP2,NCKAP1,B4GALT4,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,RINL,FRAS1,EXOC8,MDFIC,FAR2,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,DPYSL5,PCDH1,TESK1,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,G2E3,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,ITGA7,SLC2A6,LTBP2,ZDBF2,SEMA3A,RNF146,USP43,NF2,UGP2,UPF3B,FOXM1,CTDSPL,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,STIL,CYP26A1,SYTL2,TTC21B,PLK4,CDH3,VAT1,OAS3,SCN2A,LMAN1,CTDSP2,SULF2,CLCN3,TMTC1,MBP,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,ATP13A2,TAPBP,DUOX1,ATP1A1,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,ST3GAL1,ZNF701,MAN2B2,ZMAT1,BIN1,CMAS,COL9A3,GOLIM4,CDH22,KLHL13,MACC1,RUSC2,GNE,SELL,PSMD10,GTF3A,NKRF,DSE,SLC9A2,PPP2R3A,NRP2,FZD6,CD109,CCDC92,FOXP2,CDK16,BUB1,SYK,ATP2B1,GCNT1,IGDCC4,NFE2L3,HMMR,DLGAP1,HES1,RHOA,GUSB,PLAUR,STMN3,MAML2,COL7A1,FNDC3A,RNPEP,BCAR1,BSDC1,DGKE,CD83,SCRN2,SERPINA1,FAT4,CDCA7L,TMC5,CLIP4,PPP2R3C,SH3BGRL2,HIPK3,GOLGB1,DIS3L,LAMP1,SUN1,GAA,SLC35D2,PPP4R4,TTC39B,HSPG2,TMEM41B,ATP8A1,TSC22D3,PPFIBP2,PLXNA1,VASH1,PJA2,SLC9A7,NCS1,CYP1A1,SESN3,ZNF823,ELMO2,STIM1,OSBPL3,PRICKLE3,IQCE,FOSB,IL31RA,AOX1,PIK3CA,STEAP2,ATRNL1,IRF2,MTMR11,PACSIN1,ORAI2,LOC81691,SGCE,TMEM68,HSPA12A,SLC35C1,KIF13A,TNS1,GALNT7,LDB2,CCNF,ZFAND5,SLC25A5,TP53I3,POR,ARHGEF26,AHRR,RBM47,PLK2,GNPTAB,LRIG1,NKD1,BMP1,PRDM5,SERPINI1,TANC2,UNC5B,WBSCR27,TRAF5,LZTS1,FGD1,SEMA6B,MRC2,CDK17,FRMD4A,CDKN1C,DGKQ,C6orf106,ISYNA1,TNFRSF19,BMP2K,KIAA1161,MECOM,DOPEY2,SNX18,DAPK1,OPN3,PRKG1,TMEM51,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,GPR161,IGSF3,EPB41L5,DDB2,PRODH,MFI2,TBC1D8B,LPGAT1,AMER1,ANO6,VEZT,FAM133B,ATP8B3,ANTXR1,RASA1,STX3,GABRD,AP1AR,SLCO4A1,TJP3,FAAH,ISM1,PELI2,MATN2,SLC4A3,AGBL5,SFMBT1,PCDH19,NR4A2,PLIN3,MAP3K5,IFIH1,EHD1,FRMPD3,SPRED1,SLC2A4,TCTN2,REPS2,ARMCX3,NLRX1,IQGAP1,RPS6KA1,CCDC110,ATP2C2,CD274,DDR1,MNS1,ZFYVE9,EPS8L2,APLP2,ZNF75D,ACAP2,TRANK1,CNNM4,DAB2IP,PDE4D,EPHB4,LGMN,PHKA2,SULT2B1,NR2C1,DOCK4,COG2,CAPN6,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PRKCQ,PKMYT1,C15orf39,ITPR3,TRIQK,ATP10D,ZNF469,FZD7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,CCDC149,TRIOBP,NRG1,KLF5,MLKL,HS3ST3B1,SLC27A3,NR3C2,COBL,DENND5B,WASF3,HAPLN3,ATP9A,CENPI,CCNJL,HERC5,CYB561,DNAH3,TEAD3,HLA-A,LGALS3BP,SLC25A36,RASSF8,AKIRIN1,RNF128,PHF7,PTEN,FUT8,SGK3,CD9,ERBB3,CNOT6L,SPRY2,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ARAP2,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,LRRC1,GRTP1,ARSK,KIF11,GPLD1,MAMDC4,FGFR2,TBX18,ABCB1,ERAP1,CSTF2,PGM2L1,GRIN2D,ETAA1,FZD5,WDR62,NCAPG2,ARSB,ESPL1,JARID2,RGMA,EXPH5,LTBP1,CASP3,CPT2,VARS2,MPP5,DNER,CACNB4,ERP29,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,ZFYVE16,SIPA1L2,LRRC6,GRHL1,CEP78,ANKFN1,ANKRD12,AKR1B1,RAB20,CTTN,MYH14,SLC39A10,PTPRE,MYRIP,USP18,RGAG1,ARHGDIB,ROR1,ADRBK2,EDNRA,MAN2A2,ARHGEF19,GPRC5B,HPSE,KCNK1,MADD,SP6,LEMD1,CAPN1,PCSK5,ARAP3,SERPINE2,LRRFIP2,PEX6,BVES,PYROXD2,SAMD9,FAM81A,ADAMTSL4,OTUD1,B3GALNT1,ZNF432,AIM1L,KCNN4,COL6A1,LIMCH1,C10orf54,RFX5,HLA-C,SIMC1,LRIF1,SLC12A2,ALS2CL,ELK3,PODXL2,OXR1,GYLTL1B,HMG20B,RNF113A,HEATR5A,PDIK1L,RANBP9,SOX13,GLCE,GNAS,BCAR3,XKRX,ONECUT1,SLC6A6,UTP14C,ALPK3,RHOBTB2,DONSON,SHROOM2,JAK3,COL16A1,SNX30,PROM2,KLF7,CCNE2,LMO7,GAS2L1,LZTFL1,NCKAP5,SLC25A24,COL18A1,MRAS,TDRKH,OSR2,ARHGEF16,KCTD9,LRRC45,SLC25A48,SS18,ZNF687,SETDB2,CYP4F11,FRYL,ECE1,FRS3,SEPHS1,PTPRU,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,SOCS3,ARHGAP35,BHLHB9,PEX2,TLE1,SPTBN5,REEP4,ABCA1,LIFR,ANXA3,FBLIM1,TSPAN15,POC1B,FRMD6,LRP4,FAM134A,MIER3,TGFBR1,NOTUM,INTS8,POMGNT1,SBF1,FAM167A,HMGXB4,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,MLPH,LLGL2,TOX2,RRBP1,GALNS,KIAA0319,ARVCF,IQGAP3,CLIP2,MYO5A,PGM1,SYPL1,PHF20L1,SUN2,RC3H2,SYBU,OGDHL,TTC7A,RUNX3,TCEAL8,LEPR,KLHL2,ARHGAP24,HLA-B,SWAP70,PRCP,HNRNPH2,DHRS2,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,L1CAM,AHR,ABCG1,CD33 |
| 1.929e-06 | -13.16 | Downstream signaling of activated FGFR2 | REACTOME pathways | R-HSA-5654696 | 310 | 60 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.929e-06 | -13.16 | Downstream signaling of activated FGFR3 | REACTOME pathways | R-HSA-5654708 | 310 | 60 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.929e-06 | -13.16 | Downstream signaling of activated FGFR4 | REACTOME pathways | R-HSA-5654716 | 310 | 60 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.929e-06 | -13.16 | Downstream signaling of activated FGFR1 | REACTOME pathways | R-HSA-5654687 | 310 | 60 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.933e-06 | -13.16 | Signaling by FGFR | REACTOME pathways | R-HSA-190236 | 317 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 1.947e-06 | -13.15 | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | 509 | 84 | 17758 | 1761 |
PSME2,TAP1,FBXO2,RNF182,PSME1,CD274,ITPR2,PJA2,PRKACA,SH3KBP1,CALM2,RNF220,AP1M2,PSMD1,CDH1,STIM1,PLCG2,PIK3CA,CDKN1B,PIK3CD,LGMN,RASGRP1,SEC23A,SEC61B,RIPK2,AKT1,CASP9,CDC20,PRKCQ,CD40,ASB13,ITPR3,SOCS3,TRIM9,PLCG1,PPP2R5A,RAP1GAP,MRC2,NFKBIE,KLHL13,HLA-F,ASB9,KIF23,CALM3,PDIA3,SELL,PSMD10,FBXO6,PHLPP1,HLA-A,KIF5B,DTX3L,UBE2Q2,PTEN,PIK3AP1,CTSC,KLC3,UBE2J1,PRKG1,TRIM21,WWP1,HLA-C,ULBP2,SYK,KIF20A,PSMB4,NR4A1,CALM1,PIK3R1,UBE2A,YES1,KIF11,PSMA4,RASGRP2,DCTN6,HLA-B,PVRL2,NFKBIA,ERAP1,CTSA,ITGAV,ICOSLG,FBXO27,UBE2C |
| 1.956e-06 | -13.14 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 255 | 50 | 17758 | 1761 |
GRN,CMAS,SLC35D2,UGT8,FRMD4A,TTC39B,TSC22D3,EPS8,PBX3,FAM102B,NDRG2,GRK6,CAMK1D,CA8,TMCC3,CDKN2C,ZFYVE16,SP100,FAM46A,FRY,ENPP5,SGK3,DUSP10,FAM102A,CTTN,TMEM64,ARL4D,RAB27B,F2R,S100A13,MGAT5,ORAI2,ARAP2,PCBP3,CDA,PRKCQ,GRTP1,OPTN,NCOA3,ALDH5A1,PTPRJ,ACADSB,FAAH,FGD6,PGM2L1,OTUB2,VSIG10,ZMIZ1,DEF6,RUSC1 |
| 1.974e-06 | -13.14 | tube development | biological process | GO:0035295 | 573 | 94 | 16441 | 1675 |
HECA,GRHL2,LGR4,EPAS1,ST14,THRA,RET,EPHA4,CCNB1,SDC1,PRKACA,STIL,PDGFA,EPCAM,CYP1A1,SETDB2,CTGF,NPNT,DACT1,LMO4,DLG1,AKR1B1,TWIST1,TACSTD2,DAB2IP,PDE4D,ETV4,DVL2,THRB,TFAP2C,SAV1,DAG1,EDNRA,ARHGAP35,HS6ST1,SHROOM3,PTK7,TRAF3IP1,KLF5,LTA4H,COBL,PCSK5,CTHRC1,NKX3-1,SERPINE2,ITGA6,SDC4,SOX9,RAB23,CTSZ,GPSM2,NCKAP1,FZD6,CTNNBIP1,TNS3,ITGA3,GATA2,BMP7,MEGF8,BAX,TMBIM6,CITED2,WNT3A,SLC12A2,SPRY2,REC8,EPB41L5,TGIF1,HES1,PDGFC,ADAMTS2,FMN1,SALL4,RC3H2,PRICKLE1,SCRIB,NPHP3,FOXL1,NFIB,CRISPLD2,NCOA3,FAT4,FGFR2,ACVRL1,CSF1,SPINT2,TBX18,NR4A3,GDF11,PLOD3,SOX8,OSR1,RARG,ADAMTS16 |
| 1.998e-06 | -13.12 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 193 | 41 | 17758 | 1761 |
GRN,TXN,CD63,ARL4C,EFHD2,NDRG2,KCTD12,NDUFA4,IL18,IL13RA1,F11R,GSTP1,IL18R1,LMNA,DPYSL2,CST3,RRBP1,TIPARP,NAGA,S100A6,CCDC88A,PPIF,S100A4,PLEKHO1,ATP1B1,MYL12A,ETS2,DDOST,PRCP,HOXA9,AXL,SPINT2,RAB11FIP1,SH3BP4,ARRB1,ARPC2,NDFIP1,TOB1,AHR,CPPED1,CD33 |
| 2.038e-06 | -13.10 | anion binding | molecular function | GO:0043168 | 2626 | 334 | 16491 | 1673 |
ACACB,AK7,ATP8A1,RET,TAP1,DHX8,SYTL4,CAMK1D,OAT,DAPK2,WEE1,CTGF,UBE2T,ALDH1A3,PIK3CA,AOX1,TUBG1,SNX16,CRY2,PIK3CD,ACOX2,PACSIN1,TIAM1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,TP53I3,POR,ARF4,PGF,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,DHTKD1,ITPKA,ARF6,DDX58,CDK17,ALDH6A1,NUAK1,DGKQ,RAB23,KIF23,SLC1A3,FAM21C,MERTK,BMP2K,C9orf69,CYR61,SNX18,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAST4,DGKG,SYTL3,MCCC2,PRODH,KIF20A,ADCK3,AMER1,PIP4K2C,EPHA1,ATP8B3,PCTP,SPTLC2,GNA11,STX3,STK17A,DHX32,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,ITPR1,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,TMEM173,XDH,EGLN1,EHD1,PLA2G4A,MTM1,PAPSS2,NLRX1,RPS6KA1,ACTR8,IQGAP1,ATP2C2,TESK2,GRK6,AIFM2,PRKACA,DDR1,ZFYVE9,NOV,APLP2,TRANK1,DAB2IP,PDE4D,EPHB4,ACSL4,ARL4D,RAB27B,SNX10,MYO5B,MX1,RIPK2,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ITPR3,SNX12,ATP10D,NIN,EPHA10,JAK1,CDK19,STK26,AXL,MLKL,MAPK12,PCOLCE,ATP9A,ARL4C,PKN1,DNAH3,SGPL1,DIRAS3,CTSC,FAM20B,SGK3,ATP8B1,PLEKHF1,ECI2,MAPK11,ERBB3,ACBD5,OPLAH,ARAP2,SHMT1,RAPGEF2,GRIN1,UBE2A,AK4,YES1,KIF11,CPTP,CRISPLD2,ACADSB,PLOD2,FGFR2,SYT7,ACVRL1,DBI,ABCB1,RYK,CENPE,LRRK1,CMPK2,WDR45B,MELK,ACOT7,ESYT2,NMRK1,CAMKK1,EPHA4,VARS2,ITPR2,ABCD4,ZFYVE16,RAB15,RPS6KA2,PAPSS1,PASK,ABCA2,TRPC1,RAB20,RP2,MYH14,DDX59,RASGRP1,PLK1,NLRP4,ATL1,MCTP1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,RHEB,DPYSL3,MDK,WIPI1,P4HA2,PIK3C2B,NRGN,PXDC1,RRAGD,PRKAA2,LMTK3,ARAP3,RUNX2,SERPINE2,BVES,PEX6,ABCG2,TEC,RAB6A,UBE2Q2,IGF1R,KIF13B,PIM1,GAD1,CCDC88A,ABCC1,SNX7,CYP26B1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,GNAS,MAPKAPK2,NUDT16,COL13A1,PRPS2,P4HA3,NLRC5,RHOBTB2,ALPK3,LTBP2,PLD1,JAK3,SNX30,P3H2,TP53,ERBB2,MRAS,CYP26A1,SYTL2,KIF14,FABP6,SRR,PLK4,GOT1,OAS3,EGLN3,SCYL3,CTH,SEPHS1,MAP3K3,SIRT1,CLCN3,AKT1,FIGNL1,MAP3K6,ATP13A2,ARHGAP35,ATP1A1,IDE,STK38,PTK7,ANXA9,SYT13,AIFM3,ABCA1,ANXA3,PACSIN2,PINK1,TOR4A,CIT,GNE,SELL,TGFBR1,CRABP2,NRP2,TOP2A,KIF5B,ADRBK1,CDK16,BMP7,GTF2F2,UBE2J1,SGK1,BUB1,ABCD1,SYK,MYO5A,ATP2B1,RHOA,RAB3B,GCLC,OGDHL,NADK2,RUNX3,DGKE,SWAP70,RND3,RAP2C,GEM,PLOD3,UBE2C,L1CAM,HIPK3,PTGES,ABCG1 |
| 2.045e-06 | -13.10 | microtubule cytoskeleton | cellular component | GO:0015630 | 1041 | 150 | 17570 | 1756 |
NDRG2,F11R,SYTL4,CCNB1,HDAC6,CALM2,RPS6KA2,STIM1,CNTRL,DPYSL2,CEP78,DLG1,ABCA2,TUBG1,HYLS1,RP2,CTTN,ZBTB18,CCDC38,PLK1,SPEF2,PCGF5,KIFC2,SNTB2,STAU2,EZR,KLK6,PRKAR2B,KIF13A,CCNF,SLC25A5,CDK1,DZIP1L,PLEKHG6,NEIL1,MID1IP1,DNM1L,MAP2,PLK2,TRAF3IP1,FAM110C,RELL1,HSPB1,TRAF5,PIFO,NUAK1,CALM3,KIF23,FRY,KIF13B,TBCD,NEK2,LRIF1,MPHOSPH9,NUP85,TPGS2,C9orf9,KIF20A,CALM1,NUBP1,RANBP9,MAPKAPK2,AGBL5,FAM83D,AURKA,MDH1,NDE1,CFAP20,SHROOM2,HOOK1,CCNB2,RUSC1,GAS2L1,DYNLRB1,SORBS1,UPF3B,DLGAP5,CEP70,RPS6KA1,IQGAP1,ACTR8,BCL2L1,PRKACA,APC2,STIL,APPBP2,LRRC45,SS18,KIF14,PLK4,PDE4D,SNX10,ZNF365,CHP1,CAMSAP3,AKT1,CAPN6,SEPT6,CDC20,CCSAP,KIF1C,NUSAP1,SP4,GABARAPL1,NIN,CEP162,STK26,SHROOM3,TRIOBP,SPTBN5,RGS14,REEP4,TTC8,CKAP2,POC1B,RASSF7,CDCA8,DNAH3,SAC3D1,CCDC92,TOP2A,KIF5B,PHF7,CDK16,GTF2F2,TFAP2A,KLC3,CLIP2,SPRY2,MYO5A,LCA5,TACC1,FMN1,ASPM,SYBU,PARP4,RGCC,YES1,KIF11,BBS2,DCTN6,NUCB1,PPP2R3C,CENPE,GEM,CEP41,WDR62,ESPL1,SNPH,DIS3L |
| 2.049e-06 | -13.10 | C2_dom | interpro domains | IPR000008 | 160 | 36 | 18293 | 1814 |
PLA2G4A,RASA2,SYTL4,PKN1,SYTL2,WWP2,TNS3,CPNE2,PTEN,RGS3,RIMS3,PLCG2,PIK3CA,DAB2IP,CADPS2,WWP1,PIK3CD,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,TNS1,PRKCQ,ABR,RASA1,PLCH1,PLCG1,SYT7,RAB11FIP2,RAB11FIP1,INPP4B,PIK3C2B,SYT13,ESYT2 |
| 2.081e-06 | -13.08 | chrxq24 | MSigDB lists | chrxq24 | 39 | 15 | 17758 | 1761 |
LAMP2,LONRF3,ZCCHC12,WDR44,SLC9A6,RPL39,SEPT6,CUL4B,UBE2A,C1GALT1C1,NKRF,IL13RA1,SLC25A5,SLC25A43,PLS3 |
| 2.088e-06 | -13.08 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 957 | 142 | 16441 | 1675 |
CASP3,PPP4R4,DNAJC3,NDRG2,PSME1,CCNB1,HDAC6,CALM2,CDKN2C,PSMD1,ZFP36,RGS3,DLG1,DUSP10,CRY2,PLK1,CD55,TNIP1,ITCH,PBK,EZR,AGO4,PRKAR2B,POR,PIAS3,ENPP1,LIMK1,TRAF3IP1,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,LMTK3,CDKN1C,SERPINE2,DNAJB2,UBASH3B,PDCL,RAB23,CALM3,FBLN1,MECOM,TFAP4,IGF1R,PAIP2B,DAPK1,SORL1,SOCS5,CALM1,HMG20B,EIF2AK1,EPHA1,PSMA4,RANBP9,FAS,PRKAG2,SEMA4D,PLPP3,STK39,SERPINB1,TOB1,IFI6,XDH,SPRED1,NF2,FOXM1,PSME2,CAST,RPS6KA1,PTTG1,CTDSPL,TP53,SYTL2,APLP2,SVBP,DACT1,CDKN1B,TWIST1,DAB2IP,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,CAMSAP3,TIMP2,AKT1,CDC20,PKMYT1,DUSP4,DAG1,SNX12,SOCS3,DNAJC10,IDE,PTPRJ,STK38,CORO1C,RGS14,ARFGEF3,TNRC6C,PINK1,CPEB4,PSMD10,PKN1,TRIB2,GSTP1,TIPRL,SH2D4A,CD109,SNTA1,PTEN,BMP7,CST3,BAX,TRIM21,BUB1,CNOT6L,SPRY2,CRTAP,PSMB4,PLAUR,GCLC,FURIN,COL7A1,MAPK8IP1,CDK5RAP1,SWAP70,TIMP3,BANK1,SERPINA1,SPINT2,ARRB1,LRRK1,GPER1,UBE2C,HIPK3,CPEB2,PKIA,JARID2 |
| 2.092e-06 | -13.08 | KIM_MYCN_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCN_AMPLIFICATION_TARGETS_DN | 92 | 25 | 17758 | 1761 |
EPB41L5,LMO7,GCA,CEP70,TTC39B,EPAS1,RASA2,HMG20B,YES1,CAMK1D,B4GALT4,BARD1,PPP2R3A,OPTN,APOBEC3B,FAM111A,DNAJC10,CPNE2,TMEM87B,ITGB8,ZDHHC23,PLEKHG1,KLF5,PIK3CD,GOLGB1 |
| 2.106e-06 | -13.07 | vacuole | cellular component | GO:0005773 | 608 | 97 | 17570 | 1756 |
LAMP1,GAA,HSPG2,TRIP10,HEXB,SDC1,EPDR1,ABCD4,DAPK2,ATP6V0B,PQLC2,AP1M2,ABCA2,AKR1B1,SNX16,GOT1,RPN2,ECE1,TINAGL1,PIK3CD,MARCH2,TSPAN1,LGMN,NAGA,S100A13,TMEM9,GM2A,RASGRP1,LAMP3,LAMP2,EVA1A,OSTM1,SLC11A2,RNF19B,RHEB,OPTN,GABARAPL1,ATP13A2,ENPP1,HPSE,WIPI1,GLA,CAPN1,RRAGD,STARD3NL,MAN2B2,SORT1,CD63,TMEM55B,CIT,SDC4,RAB23,C6orf106,ASAH1,SLC36A4,CTSZ,M6PR,TMEM63A,MARCH8,GNS,CTSC,ARSG,ZNRF2,GATA2,VASN,CST3,GALNS,COL6A1,PCYOX1,DRAM1,PLEKHF1,SLC44A2,C9orf72,TPCN1,MYO5A,MMD,IFITM3,GUSB,LITAF,PIP4K2C,GGH,NPC2,TP53INP2,GNA11,STX3,GPLD1,CTSL,FUCA1,SCARB2,SYT7,PRCP,CTSV,NR4A3,ARRB1,CTSA,PLD1,ARSB |
| 2.152e-06 | -13.05 | TGCACTT,MIR-519C,MIR-519B,MIR-519A | MSigDB lists | TGCACTT,MIR-519C,MIR-519B,MIR-519A | 433 | 74 | 17758 | 1761 |
HECA,VANGL1,THRA,EPHA4,TESK2,FAM46C,ZFYVE9,WEE1,BTG3,DPYSL2,ENPP5,ANKRD12,SNX16,TMEM64,ACSL4,EPB41L4B,MYT1,MAP3K3,LAMP2,TIMP2,CELSR2,ITCH,ERBB2IP,PTGFRN,STK17B,NFIX,ARHGAP35,KLF12,LIMK1,STK38,ZNF367,LRIG1,ZNF704,TRIOBP,KLF11,PRR15,ARHGEF11,FRMD6,HABP4,MIER3,KIF23,EFNB1,DNAJB9,NRP2,M6PR,GNS,E2F7,BHLHE41,CALD1,FJX1,MAP3K9,SORL1,KLF9,PANX2,CCDC88A,ELK3,LPGAT1,SYBU,PIK3R1,YES1,ANKRD29,ARHGAP24,KBTBD2,CSNK1G1,ITPR1,RAP2C,NETO2,CLIP4,SFMBT1,PGM2L1,MAP3K5,CPEB2,NIPA1,PKIA |
| 2.154e-06 | -13.05 | cell periphery | cellular component | GO:0071944 | 4907 | 574 | 17570 | 1756 |
ADD1,SLC25A13,RET,CACNA2D2,NRG2,TGOLN2,LYNX1,MORF4L2,SYTL4,GRM5,CALM2,MUC4,CABP1,FUT1,CLDN4,PIK3CD,TIAM1,PRKAR2B,F12,ARF4,ABR,ENPP1,PLCG1,ATP7B,NOD2,RELL1,ARF6,HSPB1,SCN5A,ITGA6,RAB23,GPSM2,FAM21C,MERTK,TTYH3,FRY,FLRT3,PCYOX1,PANX2,NCAM1,ULBP2,DGKG,MYLIP,PAQR7,GNA11,PTPRF,SLC4A4,ETS2,SEMA4D,RAET1L,STK39,MAL2,DRP2,ARPC2,TMEM173,RUSC1,MTM1,GRHL2,CD82,RGS20,PKP2,IL13RA1,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,MUC16,SCNN1A,CDH1,ENPP5,RTKN2,LRP11,ARL4D,DLG3,RAB27B,SCN3A,ENPP4,COL6A2,FZD4,SEPT6,PLEKHO1,SYNE2,CYS1,RAB38,XRCC6BP1,GABARAPL1,IRS2,ALDH3B1,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,TRABD2A,PRIMA1,RGS14,TTC8,TCAF1,SDC4,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,NUCB2,SRPX2,NEO1,DIRAS3,CXCL16,ADD3,ITGB8,IGSF9,SLC27A6,ANKS1B,CALD1,ADAM15,TMBIM6,WWP1,IGFBP2,SGCB,TPCN1,S100A6,AMOTL2,PVRL4,PLSCR1,FMN1,RAPGEF2,PIK3R1,GRIN1,SNTB1,CNTNAP1,RAB11FIP2,ACVRL1,SYT7,ITGAV,FHL1,CYBRD1,ILDR1,BCAM,EPHA4,F11R,ITPR2,HDAC6,PDGFB,SDC1,SPTB,SUSD2,CPNE2,NPNT,SHC3,IL6ST,SLC44A1,ABCA2,NTN4,TLN2,ANO4,SMAGP,CD55,KCNIP3,CELSR2,CR2,EZR,ANLN,PLCH1,HS6ST1,MFAP3L,KCNMB4,PRKCDBP,ARRDC1,PIK3C2B,PIEZO1,PRSS8,BMF,LGALS3,FXYD3,HLA-F,RASA2,SLC22A31,NCKAP1,CNTNAP2,DHRS3,IL18R1,ANO1,B4GALNT1,IGF1R,FRAS1,TBCD,EXOC8,SELK,PIM1,WNT3A,MPHOSPH9,CKAP4,ABCC1,PCDH1,RGMB,SPATA13,SCRIB,PRX,CDK5R1,RASGRP2,EPN3,PVRL2,COL13A1,PHLPP2,ITGA7,MFSD2A,CSF1,SLC2A6,ATP1B3,PLD1,IFI6,NIPA1,NF2,ERBB2,SLC7A2,EMP2,BCAP31,SYTL2,EFR3A,PLCG2,SRR,CDH3,NOTCH3,OAS3,SCN2A,GM2A,DVL2,SULF2,CLCN3,MBP,EVA1A,AKT1,PTGER4,DAG1,ATP13A2,DUOX1,PTPRJ,IDE,ATP1A1,ABHD12,MMP17,PTK7,EFNA5,SYT13,BIN1,PACSIN2,CDH22,ADGRG1,CD63,BLVRB,GABRG2,SELL,AIP,PARM1,NRP2,SIRPA,SLC9A2,FZD6,ZDHHC21,M6PR,CD109,ALPP,CDK16,SGK1,TSPAN13,KLF9,SYK,ATP2B1,TLE6,IGDCC4,HMMR,DLGAP1,RHOA,IFITM3,CRB3,PLAUR,LITAF,BCAR1,BBS2,RNPEP,DGKE,CD83,FAT4,NETO2,ICOSLG,NDFIP1,ZBTB33,ARHGEF4,DIS3L,LAMP1,LGR4,HSPG2,SSH1,VANGL1,ATP8A1,PLXNA1,PJA2,SLC20A1,NCS1,CTGF,STIM1,RGS3,OSBPL3,IL31RA,PIK3CA,KCNS3,STEAP2,TACSTD2,HYLS1,PACSIN1,XKR8,METAP2,LAMP2,SGCE,ACVR1C,SNTB2,SLC25A5,SLC25A4,NKD1,FAM110C,UNC5B,F2RL1,TRAF5,LZTS1,DDX58,SEMA6B,HLA-E,DGKQ,SLC1A3,TSPAN7,MESDC2,ITGA3,RALGPS2,ZNRF2,PIK3AP1,LYPD3,SNX18,VASN,SLC16A6,OPN3,PRKG1,DAPK1,SORL1,CD70,TNFRSF12A,CACNA1D,SYTL3,GPR161,RIMS2,TRAK2,EPB41L5,FADS2,KCNJ12,MFI2,MMD,MICB,CALM1,ANO6,AMER1,VEZT,ATP8B3,EPHA1,ANTXR1,RASA1,STX3,FAS,DGKH,MMP15,GABRD,SLCO4A1,PLEKHH2,TJP3,SLC4A3,PCDH19,NRBP1,EHD1,SPRED1,SLC2A4,TCTN2,TRIP10,ST14,IQGAP1,ATP2C2,KCTD12,CD274,DDR1,EPS8L2,APLP2,CNNM4,DAB2IP,EPHB4,PDE4D,PHKA2,TSPAN1,MYO5B,PANK1,UTRN,PRKCQ,SLC11A2,ATP1B1,ITPR3,ALCAM,ATP10D,FZD7,EPHA10,JAK1,STK26,TSPAN18,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,COBL,ATP9A,EPS8,ARL4C,EFNB1,HLA-A,ADGRB2,SNTA1,GNB5,PTEN,CD9,SLC44A2,ATP8B1,ERBB3,SPRY2,SLC16A5,PDGFC,RASGRF1,ARHGEF28,ERMAP,MPP1,FURIN,YES1,AIF1L,CPTP,FGFR2,ABCB1,RYK,GRIN2D,GPER1,FZD5,MELK,OCLN,DEF6,ESYT2,RGMA,CASP3,MPP5,DNER,SLC8B1,CACNB4,TMC1,SH3KBP1,HTR1D,ABCD4,NKAIN3,EPCAM,RAB15,TSPAN6,DLG1,TRPC1,RAB20,RP2,CTTN,SLC39A10,MYRIP,PTPRE,RASGRP1,ITCH,ROR1,STK17B,EDNRA,GPRC5B,KCNK1,MADD,ADIPOR1,CPPED1,CAPN1,CD99,LASP1,ARAP3,SERPINE2,BVES,ABCG2,CALM3,TEC,PHLPP1,CA2,KCNN4,COL6A1,FXYD5,C10orf54,HLA-C,SLC12A2,GAD1,CCDC88A,PODXL2,BTN3A2,NUBP1,STEAP1,XKRX,GNAS,SLC6A6,UAP1,TMEM30A,PLPP3,NFKBIA,CDCA5,RHOBTB2,SHROOM2,JAK3,PROM2,SORBS1,IL15,HDAC11,MRAS,IL27RA,LRRC45,FRYL,KIF14,ECE1,PDIA6,F2R,CHP1,SEPHS1,FRS3,SUSD3,GCA,PTPRU,SLC39A8,IGSF8,ERBB2IP,CD40,JADE1,BFSP1,SECTM1,SPTBN5,LIFR,ABCA1,FBLIM1,ANXA3,SORT1,ENO2,TSPAN15,FRMD6,LRP4,TGFBR1,IL17RB,ADRBK1,ADORA1,LLGL2,KIAA0319,ARVCF,IQGAP3,SYPL1,RAB3B,LEPR,HLA-B,SWAP70,TRIM69,PRCP,CTSV,RAP2C,ARRB1,GEM,L1CAM,CD33,ABCG1 |
| 2.177e-06 | -13.04 | enzyme activator activity | molecular function | GO:0008047 | 454 | 78 | 16491 | 1673 |
ARHGAP11A,CASP3,PSME2,IQGAP1,RALBP1,ARFGEF1,RGS20,PSME1,MGST2,PDGFB,CALM2,SIPA1L2,ACAP2,SH3BP1,RGS3,PIK3CA,CDKN1B,DAB2IP,RP2,GM2A,DOCK4,TIMP2,CASP9,ARHGDIB,ATP1B1,PRKRA,ABR,ARHGAP35,DNAJC10,PLEKHG6,ARHGEF19,GPRC5B,NGFRAP1,MMP17,MADD,SIPA1L1,CAB39,AGFG2,EFNA5,NRG1,RGS14,RAP1GAP,PINK1,PCOLCE,NKX3-1,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,CALM3,FBLN1,CARD8,LLGL2,CTSC,RINL,RANBP1,FAM13B,TBCD,ERBB3,IQGAP3,SPRY2,ALS2CL,ARAP2,TBC1D8B,RAPGEF2,CALM1,RGCC,GRTP1,RASA1,CDK5R1,ARHGAP24,MMP15,PRKAG2,ARRB1,CTSA,ATP1B3,TBC1D4 |
| 2.211e-06 | -13.02 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 877 | 129 | 17775 | 1757 |
GAA,SLC25A13,CAMKK1,EPHA4,RET,CAMK1D,CDKN2C,DAPK2,WEE1,RPS6KA2,IL6ST,PIK3CA,ATRNL1,TIAM1,NEB,ERAP2,PLK1,SGCE,ACVR1C,PBK,ROR1,IDH1,ADRBK2,STK17B,PLK2,GNPTAB,LIMK1,LRIG1,CPPED1,PRKAA2,CDK17,FAM169A,ADCK5,CNTNAP2,MERTK,BMP2K,IGF1R,FRY,NEK2,DAPK1,MAP3K9,ADCK2,PRKG1,SORL1,ALPK1,PIM1,BTNL9,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,RASA1,STK17A,GNAS,MAPKAPK2,ALPK3,AURKA,CTSA,NR4A2,CDK18,MAP3K5,JAK3,NRBP1,HOXB7,RPS6KA1,GALNT12,TP53,TESK2,ERBB2,GRK6,DDR1,PRKACA,KIF14,PLK4,EPHB4,NOTCH3,SCYL3,MAP3K3,AKT1,RIPK2,SYNE2,PRKCQ,PKMYT1,MAP3K6,NIN,EPHA10,JAK1,CDK19,AXL,STK38,PTK7,NRG1,MLKL,LIFR,MAPK12,PINK1,TGFBR1,TRIB2,PKN1,KIF5B,ADRBK1,PTEN,CDK16,CALD1,KIAA0319,SGK3,SGK1,ARVCF,BUB1,MAPK11,ERBB3,SYK,OSGIN1,ASPM,PIK3R1,YES1,CD83,FAT4,FGFR2,ACVRL1,PLOD3,ZMIZ1,HIPK3,MELK,GOLGB1,TLL2 |
| 2.211e-06 | -13.02 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 877 | 129 | 17775 | 1757 |
GAA,SLC25A13,CAMKK1,EPHA4,RET,CAMK1D,CDKN2C,DAPK2,WEE1,RPS6KA2,IL6ST,PIK3CA,ATRNL1,TIAM1,NEB,ERAP2,PLK1,SGCE,ACVR1C,PBK,ROR1,IDH1,ADRBK2,STK17B,PLK2,GNPTAB,LIMK1,LRIG1,CPPED1,PRKAA2,CDK17,FAM169A,ADCK5,CNTNAP2,MERTK,BMP2K,IGF1R,FRY,NEK2,DAPK1,MAP3K9,ADCK2,PRKG1,SORL1,ALPK1,PIM1,BTNL9,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,RASA1,STK17A,GNAS,MAPKAPK2,ALPK3,AURKA,CTSA,NR4A2,CDK18,MAP3K5,JAK3,NRBP1,HOXB7,RPS6KA1,GALNT12,TP53,TESK2,ERBB2,GRK6,DDR1,PRKACA,KIF14,PLK4,EPHB4,NOTCH3,SCYL3,MAP3K3,AKT1,RIPK2,SYNE2,PRKCQ,PKMYT1,MAP3K6,NIN,EPHA10,JAK1,CDK19,AXL,STK38,PTK7,NRG1,MLKL,LIFR,MAPK12,PINK1,TGFBR1,TRIB2,PKN1,KIF5B,ADRBK1,PTEN,CDK16,CALD1,KIAA0319,SGK3,SGK1,ARVCF,BUB1,MAPK11,ERBB3,SYK,OSGIN1,ASPM,PIK3R1,YES1,CD83,FAT4,FGFR2,ACVRL1,PLOD3,ZMIZ1,HIPK3,MELK,GOLGB1,TLL2 |
| 2.212e-06 | -13.02 | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | 187 | 40 | 17758 | 1761 |
BIN1,SIGIRR,HECA,ALDH6A1,HAPLN3,GALNT12,EPHA4,MORC4,AES,ANO9,C3orf18,EPS8L2,TMEM63A,ZNF75D,BDH1,TMEM143,FXYD5,ANKRD12,TRPC1,WWP1,PIM1,MAST4,RASGRP1,SUSD3,SLC39A8,STMN3,ITPR3,PRIM1,OPTN,PLCG1,ATP1A1,LRIG1,AMMECR1,SFMBT1,CAB39,FAM117A,SLC25A38,ST3GAL1,CBX7,DOCK9 |
| 2.212e-06 | -13.02 | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | 187 | 40 | 17758 | 1761 |
CD99,LASP1,SLC2A4,SORBS1,EPAS1,ATP8A1,SOX9,TGFBR1,ETS1,CA8,SIRPA,RAD23A,APLP2,PTEN,IL6ST,TMEM143,DAPK1,GM2A,CPD,FADS2,TIMP2,AKT1,GUSB,FZD4,SNTB2,LPGAT1,PIK3R1,KIF1C,TNS1,TCF7,ZBTB7B,NFIB,MAPK8IP1,NFIX,DPYSL3,GNAS,EIF4EBP2,NR2C2,EHD1,EGLN1 |
| 2.279e-06 | -12.99 | MEL18_DN.V1_UP | MSigDB lists | MEL18_DN.V1_UP | 135 | 32 | 17758 | 1761 |
ARL4C,TAP1,PLXNA1,SRPX2,TNFSF9,FZD6,NRP2,CCND1,ITGA3,ITGB8,SLC16A6,FJX1,TMEM51,SUN2,PLAUR,MICB,C3orf52,FURIN,COL7A1,ITPR3,LHFPL2,CRISPLD2,ATP13A2,CD83,MMP15,SLCO4A1,COL13A1,CSF1,LRIG1,SLC2A6,PIEZO1,COL16A1 |
| 2.301e-06 | -12.98 | JOHNSTONE_PARVB_TARGETS_3_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_DN | 850 | 126 | 17758 | 1761 |
ARHGAP11A,CCNE2,SLC25A24,SPC25,CEP70,DLGAP5,NQO1,AASS,MRPS15,BROX,DNAJC3,RALBP1,CNOT8,TMX4,PTTG1,NDC80,NUF2,BARD1,MNS1,CENPN,CMTM6,FANCI,CDKN2C,APLP2,BTG3,ACAP2,AOX1,SRR,PLK4,ANKRD12,SNX16,RTKN2,RP2,CTTN,PDIA6,TRAM1,MYBL1,TIPARP,NR2C1,ERAP2,LAMP2,TMEM200B,SMARCA2,CENPA,FIGNL1,PBK,SNTB2,SERTAD4,CDC20,NUSAP1,GLO1,PRKAR2B,ATP1B1,PRKRA,GTF2A2,H2AFV,CDK1,RHEB,ARHGAP35,SOCS3,RBL1,AXL,ZNF367,CYP2U1,E2F8,STARD3NL,GOLIM4,ALDH6A1,CKAP2,FRMD6,POC1B,ETV5,CDCA8,KIF23,SLC36A4,GPSM2,NCKAP1,PM20D2,NUCB2,SLC25A43,TIPRL,PSIP1,IRF2BPL,TOP2A,MDM1,PTEN,SPIN4,CTSC,FAM13B,RUNDC3B,NEK2,BUB1,SELK,ALDH7A1,IQGAP3,CNOT6L,MPHOSPH9,RIMS2,MYO5A,SNX7,ZWINT,PSMB4,PLSCR1,ASPM,MICB,RAPGEF2,OXR1,NUB1,MRS2,C2orf69,PDK3,YES1,KIF11,G2E3,CYB5A,SLC6A6,UAP1,TWSG1,CDCA7L,PRPS2,ERAP1,ATP1B3,CENPE,PER3,NCAPG2,MELK |
| 2.324e-06 | -12.97 | BROWNE_HCMV_INFECTION_48HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_UP | 174 | 38 | 17758 | 1761 |
ANXA3,COL9A3,LRP4,RET,HMGN3,ITPR2,IL18R1,IER3,CYP1A1,PLCG2,RUNDC3B,IGFBP2,ZNF365,CTH,CKS2,CD55,CELSR2,MRS2,EZR,GGH,RUNX3,PDK3,CCNF,SLC25A5,FUCA1,MAN2A2,ONECUT1,ITPR1,PRPS2,PPM1H,CCDC69,TLE1,GEM,LIFR,PTGES,COBL,GAB1,ABCG1 |
| 2.344e-06 | -12.96 | WGGAATGY_V$TEF1_Q6 | MSigDB lists | WGGAATGY_V$TEF1_Q6 | 351 | 63 | 17758 | 1761 |
SPRED1,BCAM,AVPI1,IGFBP6,GALNT12,ERBB2,NRG2,COL4A5,DDR1,SRPX2,SPTB,SIX4,PRRG4,LMNA,SYTL2,APPBP2,ELF3,PLS3,FOXP2,CDKN2C,PDGFA,SCNN1A,ST5,ITGA3,CTGF,CYR61,SH3BP1,RGS3,DACT1,IL6ST,CDH3,TINAGL1,DLG3,ZNF462,SMARCA2,TGIF1,NR4A1,KIF1C,KLK6,LRRC1,ITPR3,MYL12A,PRX,RASGRP2,MDK,PGF,PIAS3,ARHGAP24,PTPRJ,RBM47,WIPI1,FGFR2,NR4A3,PRKCDBP,NRG1,SH3BGRL2,HMGA1,HOOK1,LIFR,RARG,HOXC13,DIS3L,EHD1 |
| 2.361e-06 | -12.96 | FRASOR_TAMOXIFEN_RESPONSE_UP | MSigDB lists | FRASOR_TAMOXIFEN_RESPONSE_UP | 49 | 17 | 17758 | 1761 |
SUN2,LTBP1,LASP1,B3GNT2,IL13RA1,SDC1,MECOM,ELF3,IER3,SERPINA1,CDK19,KBTBD2,RGS3,PCYOX1,PGRMC1,CDK18,PKIA |
| 2.488e-06 | -12.90 | GNF2_RRM1 | MSigDB lists | GNF2_RRM1 | 87 | 24 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,CDCA8,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,KIF14,PLK4,AURKA,CENPE,UBE2C,CCNB2,E2F8,MELK,METAP2,CKS2 |
| 2.510e-06 | -12.90 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3077 | 375 | 17775 | 1757 |
ACACB,SSH1,HSPG2,SLC25A13,RET,PPFIBP2,NRG2,MORF4L2,CARD10,LTBP3,GRM5,WEE1,CYP1A1,ELMO2,OSBPL3,FOSB,AOX1,PIK3CA,ATRNL1,HYLS1,TINAGL1,PIK3CD,TIAM1,SMYD5,TIPARP,ORAI2,TNIP1,SPATA18,ACVR1C,CASP9,PRKAR2B,TNS1,SAV1,PPP1R14C,CCNF,COL12A1,PIAS3,PLCG1,RBM47,ATP7B,HDAC1,TRAF5,HSPB1,GAB1,E2F8,HOXC13,SEMA6B,SCN5A,MRPL44,NFKBIE,ITGA6,SOX9,RAB23,MERTK,PSIP1,MECOM,RAVER2,ELF3,ZNRF2,AIM1,NEK2,RUNDC3B,DAPK1,PRKG1,SORL1,ULBP2,C9orf72,PAQR7,SOCS5,EPB41L5,DDB2,KCNJ12,MFI2,ZNF84,STAT4,AMER1,ELK1,RASA1,FAS,STK17A,PTPRF,CACHD1,PRKAG2,SLC4A4,ETS2,ITPR1,AGBL5,AURKA,CDK18,NDE1,MAP3K5,PER3,PLA2G4A,SPRED1,TPRN,TRIP10,GALNT12,DDIT4L,IQGAP1,RALBP1,ATP2C2,RNF182,BCL2L1,PRKACA,DDR1,MNS1,REPS1,RCN1,CCND1,MUC16,ST5,CDH1,CDKN1B,DAB2IP,ACSL4,EPHB4,ZNF365,ETV4,SCN3A,MYO5B,FZD4,SEPT6,SYNE2,UTRN,PRKCQ,PKMYT1,C15orf39,ITPR3,FZD7,EPHA10,IRS2,PPP2R5A,JAK1,SHROOM3,AXL,PLEKHG1,NRG1,MAPK12,TNRC6C,IGFBP6,CKAP2,CENPI,EPS8,OSGIN2,HERC5,PKN1,ETS1,DNAH3,FGF19,LGALS3BP,SIX4,TMCC3,NEO1,WWP2,PDIA4,DTX3L,DIRAS3,SNTA1,PHF7,PTEN,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERBB3,SPRY2,NCOA2,PARP9,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,PARP4,UBE2A,FURIN,FOS,GPLD1,CNTNAP1,FGFR2,PPM1H,GRIN2D,ITGAV,OSR1,FZD5,TLL2,JARID2,LTBP1,CASP3,PPM1J,EPHA4,NDRG2,TEX2,MGAT5B,PDGFB,SDC1,DNER,KREMEN1,SPTB,SH3KBP1,RPS6KA2,LRRC6,CNTRL,MKRN3,SLC44A1,MITF,DUSP10,TLN2,MYBL1,CCDC38,RASGRP1,CYP1B1,LAMP3,ZNF462,PLK1,CELSR2,USP18,STAU2,ITCH,RGAG1,CR2,ARHGDIB,ROR1,ANLN,ADRBK2,RHEB,EDNRA,DPYSL3,LRRC42,MAN2A2,NEIL1,GPRC5B,P4HA2,HOXA9,MADD,PIK3C2B,PRKAA2,LASP1,RUNX2,PARP12,HJURP,RASA2,ETV5,CALM3,SAMD9,CNTNAP2,ADAMTSL4,OTUD1,TNS3,IGF1R,PIM1,ZRANB1,CCDC88A,DPYSL5,ELK3,PLEKHA6,OXR1,SPATA13,PDE5A,VWA1,C3orf58,STEAP1,G2E3,RASGRP2,GNAS,MAPKAPK2,UAP1,PVRL2,NFKBIA,RHOBTB2,YOD1,EGFL7,PLD1,SHROOM2,JAK3,TOB1,RARG,USP43,LMO7,NF2,FOXM1,TP53,CCDC68,ERBB2,MRAS,TDRKH,STIL,PHLDA1,KCTD9,PDGFA,ATP6V0B,SS18,SETDB2,CYP4F11,EFR3A,N4BP3,PLCG2,ZDHHC23,BCL6,CDH3,ESPN,RPN2,TWIST1,NOTCH3,SCN2A,DVL2,MAP3K3,AKT1,PTPRU,ACO1,PTGER4,CD40,DUSP4,FANCE,CASP4,MAP3K6,SOCS3,DNAJC10,ALDH5A1,PTPRJ,PTK7,STK38,CYP2U1,ABCA1,LIFR,SORT1,TSPAN15,ARHGEF11,KLHL13,RUSC2,FRMD6,LRP4,TGFBR1,NKRF,COL4A5,INTS8,VPS26A,PPP2R3A,FZD6,CD109,FOXP2,TAF1B,MYCL,UBE2J1,SGK1,BUB1,SYK,MYO5A,PGM1,HES1,RHOA,NR3C1,AMFR,ASPM,RC3H2,PRICKLE1,MAML2,COL7A1,BCAR1,MAPK8IP1,ARHGAP24,FAT4,C2orf70,RND3,RAP2C,DTX4,OTUB2,ARRB1,GEM,TBC1D4,ABCG1,DIS3L,GOLGB1 |
| 2.510e-06 | -12.90 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3077 | 375 | 17775 | 1757 |
ACACB,SSH1,HSPG2,SLC25A13,RET,PPFIBP2,NRG2,MORF4L2,CARD10,LTBP3,GRM5,WEE1,CYP1A1,ELMO2,OSBPL3,FOSB,AOX1,PIK3CA,ATRNL1,HYLS1,TINAGL1,PIK3CD,TIAM1,SMYD5,TIPARP,ORAI2,TNIP1,SPATA18,ACVR1C,CASP9,PRKAR2B,TNS1,SAV1,PPP1R14C,CCNF,COL12A1,PIAS3,PLCG1,RBM47,ATP7B,HDAC1,TRAF5,HSPB1,GAB1,E2F8,HOXC13,SEMA6B,SCN5A,MRPL44,NFKBIE,ITGA6,SOX9,RAB23,MERTK,PSIP1,MECOM,RAVER2,ELF3,ZNRF2,AIM1,NEK2,RUNDC3B,DAPK1,PRKG1,SORL1,ULBP2,C9orf72,PAQR7,SOCS5,EPB41L5,DDB2,KCNJ12,MFI2,ZNF84,STAT4,AMER1,ELK1,RASA1,FAS,STK17A,PTPRF,CACHD1,PRKAG2,SLC4A4,ETS2,ITPR1,AGBL5,AURKA,CDK18,NDE1,MAP3K5,PER3,PLA2G4A,SPRED1,TPRN,TRIP10,GALNT12,DDIT4L,IQGAP1,RALBP1,ATP2C2,RNF182,BCL2L1,PRKACA,DDR1,MNS1,REPS1,RCN1,CCND1,MUC16,ST5,CDH1,CDKN1B,DAB2IP,ACSL4,EPHB4,ZNF365,ETV4,SCN3A,MYO5B,FZD4,SEPT6,SYNE2,UTRN,PRKCQ,PKMYT1,C15orf39,ITPR3,FZD7,EPHA10,IRS2,PPP2R5A,JAK1,SHROOM3,AXL,PLEKHG1,NRG1,MAPK12,TNRC6C,IGFBP6,CKAP2,CENPI,EPS8,OSGIN2,HERC5,PKN1,ETS1,DNAH3,FGF19,LGALS3BP,SIX4,TMCC3,NEO1,WWP2,PDIA4,DTX3L,DIRAS3,SNTA1,PHF7,PTEN,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERBB3,SPRY2,NCOA2,PARP9,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,PARP4,UBE2A,FURIN,FOS,GPLD1,CNTNAP1,FGFR2,PPM1H,GRIN2D,ITGAV,OSR1,FZD5,TLL2,JARID2,LTBP1,CASP3,PPM1J,EPHA4,NDRG2,TEX2,MGAT5B,PDGFB,SDC1,DNER,KREMEN1,SPTB,SH3KBP1,RPS6KA2,LRRC6,CNTRL,MKRN3,SLC44A1,MITF,DUSP10,TLN2,MYBL1,CCDC38,RASGRP1,CYP1B1,LAMP3,ZNF462,PLK1,CELSR2,USP18,STAU2,ITCH,RGAG1,CR2,ARHGDIB,ROR1,ANLN,ADRBK2,RHEB,EDNRA,DPYSL3,LRRC42,MAN2A2,NEIL1,GPRC5B,P4HA2,HOXA9,MADD,PIK3C2B,PRKAA2,LASP1,RUNX2,PARP12,HJURP,RASA2,ETV5,CALM3,SAMD9,CNTNAP2,ADAMTSL4,OTUD1,TNS3,IGF1R,PIM1,ZRANB1,CCDC88A,DPYSL5,ELK3,PLEKHA6,OXR1,SPATA13,PDE5A,VWA1,C3orf58,STEAP1,G2E3,RASGRP2,GNAS,MAPKAPK2,UAP1,PVRL2,NFKBIA,RHOBTB2,YOD1,EGFL7,PLD1,SHROOM2,JAK3,TOB1,RARG,USP43,LMO7,NF2,FOXM1,TP53,CCDC68,ERBB2,MRAS,TDRKH,STIL,PHLDA1,KCTD9,PDGFA,ATP6V0B,SS18,SETDB2,CYP4F11,EFR3A,N4BP3,PLCG2,ZDHHC23,BCL6,CDH3,ESPN,RPN2,TWIST1,NOTCH3,SCN2A,DVL2,MAP3K3,AKT1,PTPRU,ACO1,PTGER4,CD40,DUSP4,FANCE,CASP4,MAP3K6,SOCS3,DNAJC10,ALDH5A1,PTPRJ,PTK7,STK38,CYP2U1,ABCA1,LIFR,SORT1,TSPAN15,ARHGEF11,KLHL13,RUSC2,FRMD6,LRP4,TGFBR1,NKRF,COL4A5,INTS8,VPS26A,PPP2R3A,FZD6,CD109,FOXP2,TAF1B,MYCL,UBE2J1,SGK1,BUB1,SYK,MYO5A,PGM1,HES1,RHOA,NR3C1,AMFR,ASPM,RC3H2,PRICKLE1,MAML2,COL7A1,BCAR1,MAPK8IP1,ARHGAP24,FAT4,C2orf70,RND3,RAP2C,DTX4,OTUB2,ARRB1,GEM,TBC1D4,ABCG1,DIS3L,GOLGB1 |
| 2.542e-06 | -12.88 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 2864 | 361 | 16441 | 1675 |
ACACB,TXN,LGR4,DNAJC3,HEXB,RET,NRG2,PSME1,IL18,MORF4L2,CAMK1D,CCNB1,CARD10,GRM5,CALM2,PSMD1,CTGF,ZFP36,IL31RA,FOSB,PIK3CA,IRF2,SMARCA2,TNIP1,ACVR1C,CASP9,TFAP2C,PRKAR2B,F12,LDB2,SAV1,RNF19B,POR,ARF4,AHRR,PIAS3,PLCG1,MID1IP1,ANKRD6,PLK2,NOD2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,GAB1,HOXC13,DDX58,CDKN1C,SCOC,ITGA6,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,NEK2,DAPK1,MAP3K9,MYDGF,NCAM1,NUP85,GPR161,SOCS5,MMD,MFI2,SALL4,STAT4,CALM1,PYM1,MYBL2,PIP4K2C,ELK1,TP53INP2,PSMA4,NFIB,PLIN5,RASA1,FAS,NCOA3,PRKAG2,ETS2,SEMA4D,PELI2,SETD3,AURKA,NR4A2,STK39,GDF11,MAP3K5,TMEM173,XDH,SPRED1,ARMCX3,GRHL2,DLGAP5,THRA,RPS6KA1,IQGAP1,PRKACA,CCND1,ST5,CDH1,SP100,CDKN1B,DAB2IP,RASGEF1A,ETV4,MED30,RIPK2,FZD4,FOXJ2,CDCA2,PRKCQ,SLC11A2,PYGO1,GTF2A2,FZD7,NFIX,IRS2,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,SLC27A1,KLF5,NRG1,MAPK12,PCOLCE,NKX3-1,TNRC6C,CKAP2,SDC4,PBX3,PKN1,ETS1,GSTP1,FGF19,TEAD3,SIX4,WWP2,E2F7,RNF128,CTSC,PTEN,CST3,BAX,PLEKHF1,MAPK11,ERBB3,CITED2,TRIM62,SPRY2,NCOA2,RASGRF1,PDGFC,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,FURIN,YES1,FOS,GPLD1,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,RYK,GRIN2D,GPER1,HMGA1,CENPE,LRRK1,FZD5,OSR1,USF2,ESPL1,RGMA,JARID2,CASP3,EPAS1,CNOT8,CAMKK1,EPHA4,ARFGEF1,NENF,HDAC6,PDGFB,ERP29,SPTB,FANCI,EPCAM,HSF2,GRHL1,NPNT,SHC3,IL6ST,ELF5,PASK,MITF,DLG1,SLC39A10,MYBL1,RASGRP1,ZNF462,PLK1,THRB,PCGF5,TRIM8,CITED4,NFE2L1,EZR,CDK1,EDNRA,KDM4D,MDK,GPRC5B,KLF12,MADD,PRKCDBP,CAB39,MAFF,NR2C2,PRKAA2,PIFO,RUNX2,BVES,RASA2,DNAJB2,ETV5,CALM3,TEC,FBLN1,DAZAP1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,CCDC88A,MDFI,ELK3,RGMB,STRADB,PDE5A,SCRIB,CDK5R1,GNAS,BCAR3,MAPKAPK2,ONECUT1,NUDT16,PLPP3,CSF1,NFKBIA,SH3BP4,NLRC5,JAK3,TOB1,RARG,PROM2,KLF7,SORBS1,AVPI1,UPF3B,IL15,FOXM1,PSME2,TP53,ERBB2,OSR2,LPIN3,EMP2,STIL,BCAP31,PDGFA,SS18,LMO4,KIF14,PLCG2,BCL6,CDH3,TWIST1,ECE1,NOTCH3,EGLN3,F2R,DVL2,FRS3,CTH,CHP1,MAP3K3,SIRT1,CLCN3,TIMP2,AKT1,CDC20,SERTAD3,CD40,MAP3K6,JADE1,RBL1,IRF7,SPTBN5,EFNA5,ABCA1,GLIS3,ANXA3,PINK1,CD63,ARHGEF11,DAP,PSMD10,TGFBR1,HMGN3,GDF15,TRIB2,PARM1,IRF2BPL,TOP2A,CARD8,ADORA1,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,IQGAP3,SYK,NFE2L3,HES1,RHOA,PSMB4,NR3C1,PLAUR,GCLC,NR4A1,RGCC,PPARA,PRICKLE1,MAML2,RUNX3,BANK1,RAP2C,NMI,ARRB1,PPP2R3C,ZMIZ1,SOX8,NDFIP1,UBE2C,AHR |
| 2.545e-06 | -12.88 | SASAKI_ADULT_T_CELL_LEUKEMIA | MSigDB lists | SASAKI_ADULT_T_CELL_LEUKEMIA | 168 | 37 | 17758 | 1761 |
CD99,DLGAP5,FOXM1,ATP8A1,PTTG1,SELL,CCNB1,TRIB2,ETS1,BARD1,FZD6,PARM1,TOP2A,KCNN4,KIF14,TFAP2A,DLG3,PLK1,SGCE,SMARCA2,ZWINT,ING1,ATP1B1,ICMT,KIF11,IDH1,RASA1,FAS,PRDX4,PTPRJ,GDE1,NMI,HDAC1,PLD1,CCNB2,JAK3,UBE2C |
| 2.572e-06 | -12.87 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 827 | 123 | 17758 | 1761 |
ARHGAP11A,SLC25A24,TRIM2,SPC25,DLGAP5,SLC25A13,EPHA4,NDC80,RGS20,ARFGEF1,PJA2,BARD1,STIL,ZFYVE9,APPBP2,IER3,CCND1,ZFYVE16,ACAP2,ST5,RPS6KA2,CTGF,SP100,EFR3A,FRYL,KIF14,MITF,DLG1,CDKN1B,TRPC1,ACSL4,MYBL1,TIPARP,TIAM1,DOCK4,SMARCA2,CENPA,ITCH,PTPN9,STAU2,SYNE2,SLC11A2,ROR1,DUSP4,LHFPL2,ALCAM,ARHGAP35,PPP2R5A,CDK19,SIPA1L1,LRIG1,TLE1,NRG1,EFNA5,WASF3,CDK17,FAM169A,NUAK1,ITGA6,GNE,SOX9,EPS8,KIF23,PBX3,NCKAP1,RAB6A,PHLPP1,HOXB2,TIPRL,BMP2K,PPP2R3A,HMGXB4,MECOM,TOP2A,DOPEY2,IGF1R,PTEN,CYR61,FUT8,GTF2F2,TPST1,DAPK1,ATP8B1,MDFIC,WWP1,LIMCH1,PIKFYVE,MPHOSPH9,NCOA2,ATP2B1,ABCC1,GCNT1,SOCS5,HMMR,TGIF1,ARAP2,PLSCR1,NR3C1,RAPGEF2,PLAUR,FNDC3A,KIF11,NFIB,RASA1,BCAR3,NCOA3,SWAP70,PLOD2,SETD3,PHLPP2,ITPR1,RYK,AURKA,SFMBT1,STK39,CENPE,ZMIZ1,AFAP1,MELK,KLF7,JARID2,DOCK9,TMEM131 |
| 2.629e-06 | -12.85 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1430 | 198 | 16441 | 1675 |
CASP3,TXN,DNAJC3,CAMKK1,EPHA4,RET,ARFGEF1,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,FANCI,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PASK,PIK3CA,DLG1,SLC39A10,RASGRP1,PLK1,ACVR1C,CASP9,EZR,PRKAR2B,F12,RNF19B,CDK1,PIAS3,PLCG1,GPRC5B,ANKRD6,PLK2,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,DNAJB2,RASA2,SOX9,CALM3,TEC,FBLN1,TFAP4,IGF1R,CYR61,DAPK1,MAP3K9,MDFIC,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,MDFI,SOCS5,MMD,MFI2,CALM1,PYM1,PDE5A,STRADB,PSMA4,RASA1,CDK5R1,FAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,NFKBIA,AURKA,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,DLGAP5,UPF3B,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,BCAP31,PDGFA,CCND1,ST5,KIF14,BCL6,CDKN1B,DAB2IP,RASGEF1A,EGLN3,F2R,DVL2,FRS3,CHP1,MAP3K3,SIRT1,TIMP2,RIPK2,AKT1,FZD4,CDC20,SLC11A2,CDCA2,CD40,MAP3K6,FZD7,IRS2,PPP2R5A,JAK1,STK26,NGFRAP1,WFS1,SLC27A1,NRG1,SPTBN5,EFNA5,MAPK12,PINK1,NKX3-1,PCOLCE,DAP,SDC4,PSMD10,TGFBR1,GDF15,PKN1,TRIB2,FGF19,CARD8,ADORA1,RNF128,CTSC,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,RHOA,PSMB4,RAPGEF2,PLAUR,GCLC,NUB1,EIF5A2,GRIN1,RGCC,FURIN,PRICKLE1,YES1,GPLD1,BANK1,FGFR2,ACVRL1,RAP2C,NMI,RYK,ARRB1,PPP2R3C,GRIN2D,GPER1,LRRK1,CENPE,FZD5,NDFIP1,UBE2C,ESPL1,JARID2 |
| 2.632e-06 | -12.85 | HALLMARK_COMPLEMENT | MSigDB lists | HALLMARK_COMPLEMENT | 195 | 41 | 17758 | 1761 |
PLA2G4A,CASP3,LGALS3,CALM3,PDGFB,HPCAL4,CALM2,CA2,CTSC,PIK3CA,IRF2,PIM1,LGMN,DGKG,S100A13,APOBEC3G,RASGRP1,ERAP2,DOCK4,LAMP2,GCA,KCNIP3,CD55,TIMP2,PLSCR1,PLAUR,CASP9,CALM1,CDA,CR2,CASP4,CDK5R1,DGKH,MMP15,SERPINA1,PRCP,IRF7,LTA4H,MAFF,DOCK9,EHD1 |
| 2.632e-06 | -12.85 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | 195 | 41 | 17758 | 1761 |
GAA,NFKBIE,BLVRB,EFHD2,IL13RA1,SEPP1,GSTP1,SIRPA,BMP2K,LMNA,SGPL1,C7orf49,LYPD3,DPYSL2,CST3,PLCG2,DAPK1,VAT1,RAB20,AHCY,LIMCH1,LGMN,NAGA,MYO5A,FAH,GPX4,LAMP2,PDGFC,FADS2,MMD,MBNL3,NPC2,ADRBK2,POR,CD83,FUCA1,LRRC42,PLK2,TCEAL4,CTSA,ZMIZ1 |
| 2.632e-06 | -12.85 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | 195 | 41 | 17758 | 1761 |
SUN1,PBX3,CYB561,IL18,SYTL2,M6PR,PLS3,CD109,EPCAM,NPNT,KIF13B,OSBPL3,CYP2S1,FUT8,PIK3CA,ADAM15,TRPC1,TMEM37,LGMN,LRP11,GM2A,S100A6,DPYSL5,LOC81691,ADAMTS2,STMN3,COL7A1,ALCAM,ANKRD29,CASP4,GALNT3,CXXC4,HLF,PTPRJ,HPSE,H1F0,UEVLD,RELL1,FBXO27,COBL,CD33 |
| 2.632e-06 | -12.85 | GSE360_CTRL_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_DC_DN | 195 | 41 | 17758 | 1761 |
CDK17,ENO2,PSME2,SOX9,TAP1,NDRG2,PSME1,H1FX,IER3,SGPL1,PLS3,TYMP,LLGL2,LYPD3,FRYL,CABP1,ATP8B1,PIM1,MARCH2,DLGAP1,FBLN5,IFITM3,SLC39A8,LITAF,CD40,RNF19B,NFIB,IRS2,PITX2,SERPINA1,ETS2,CGREF1,SECTM1,BMP1,ITGAV,ATP1B3,HSPB1,AHR,GAB1,IFI6,RRAGD |
| 2.665e-06 | -12.84 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 105 | 27 | 17758 | 1761 |
CPD,LMO7,TGIF1,SLC35D2,TBC1D1,IQGAP1,LPGAT1,ITGA6,SOX9,TGFBR1,DUSP4,SLC20A1,DDR1,NCS1,HMGXB4,DHX32,IER3,PDGFA,RBM47,CTGF,FGD6,SGK1,CLDN4,MAL2,LGMN,UNC5B,C9orf72 |
| 2.671e-06 | -12.83 | Signaling by VEGF | REACTOME pathways | R-HSA-194138 | 320 | 61 | 8202 | 867 |
WASF3,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,NCKAP1,PRKACA,PDGFB,SPTB,FGF19,NRP2,CALM2,PDGFA,PSMD1,ELMO2,SHC3,PIK3CA,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,RHOA,PSMB4,AKT1,RAPGEF2,CALM1,PIK3R1,GRIN1,DUSP4,ITPR3,BCAR1,PSMA4,RASA1,MAPKAPK2,IRS2,PGF,PLCG1,PPP2R5A,JAK1,FGFR2,AXL,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,ITGAV,JAK3,HSPB1,MAPK12 |
| 2.673e-06 | -12.83 | MARTINEZ_RB1_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_TARGETS_UP | 648 | 101 | 17758 | 1761 |
SLC2A4,SORBS1,ADD1,DNAJC3,SLC25A13,TP53,OSR2,DDR1,EMP2,BCAP31,SH3KBP1,IER3,CCND1,APLP2,WEE1,FRYL,ZFP36,IL6ST,KLF3,ABCA2,CDH3,RPN2,TECR,LMAN1,PTPRE,SULT2B1,CTDSP2,MYO5B,CPD,PLK1,CLCN3,CENPA,COL6A2,CAPN6,PBK,USP18,ACO1,SLC11A2,GLO1,DPYSL3,IDE,JAK1,HOXA9,BMP1,OVOL1,TMOD2,SLC25A30,CD99,LASP1,PCOLCE,PINK1,MRC2,HJURP,SCOC,SOX9,ERI2,COL4A5,RAB6A,FAM21C,FBLN1,TNFRSF19,EFNB1,HOXB2,LGALS3BP,SIRPA,TMCC3,SGPL1,ADD3,FUT2,CYR61,CALD1,DRAM1,FAH,FADS2,SHMT1,KIF20A,NR3C1,ZC3H11A,NR4A1,GCLC,ELOVL3,TCF7,AIF1L,KIF11,NUBP1,RANBP9,FRMD4B,FECH,GNAS,FUCA1,PTPRF,TIMP3,TWSG1,FGFR2,ITGAV,PLD1,MAP3K5,HIPK3,RARG,SNX30,XDH |
| 2.755e-06 | -12.80 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 970 | 143 | 16441 | 1675 |
TXN,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PIK3CA,DLG1,RASGRP1,PLK1,PRKAR2B,CDK1,PLCG1,GPRC5B,ANKRD6,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,RASA2,SOX9,CALM3,TEC,IGF1R,CYR61,MAP3K9,MDFIC,PIM1,MYDGF,NCAM1,WNT3A,CCDC88A,MDFI,MMD,CALM1,PDE5A,STRADB,PSMA4,CDK5R1,RASA1,FAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,ST5,KIF14,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,SIRT1,MAP3K3,TIMP2,AKT1,RIPK2,FZD4,CD40,MAP3K6,FZD7,IRS2,JAK1,STK26,SLC27A1,NRG1,SPTBN5,EFNA5,NKX3-1,PINK1,SDC4,PSMD10,GDF15,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,PSMB4,PLAUR,RAPGEF2,GRIN1,RGCC,YES1,BANK1,ACVRL1,FGFR2,RAP2C,RYK,ARRB1,GRIN2D,PPP2R3C,LRRK1,CENPE,GPER1,FZD5 |
| 2.802e-06 | -12.79 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 17602 | 1755 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,NR4A3,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PXDC1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,LHX6,PLCG2,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.881e-06 | -12.76 | endoplasmic reticulum lumen | cellular component | GO:0005788 | 201 | 42 | 17570 | 1756 |
COL9A3,P3H2,DNAJC3,PDIA5,PDIA3,COL18A1,DNAJB11,CTSZ,COL4A5,PDGFB,ADAMTSL4,ERP29,DNAJB9,PDIA4,PDGFA,RCN1,CTSC,ARSG,COL6A1,MYDGF,MINPP1,WNT3A,CNPY3,PDIA6,CRTAP,ERAP2,PDGFC,COL6A2,ERLEC1,PLAUR,ERO1A,COL7A1,ARSK,COL12A1,DNAJC10,SERPINA1,COL13A1,P4HA2,P4HA3,ERAP1,ARSB,COL16A1 |
| 2.900e-06 | -12.75 | Fc epsilon receptor (FCERI) signaling | REACTOME pathways | R-HSA-2454202 | 342 | 64 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,PSME1,ITPR2,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKCQ,AGO4,DUSP4,ITPR3,IRS2,PLCG1,JAK1,PPP2R5A,NRG1,SPTBN5,GAB1,TNRC6C,RASA2,CALM3,PSMD10,TEC,PHLPP1,FGF19,PTEN,ERBB3,NCAM1,SYK,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,FOS,PSMA4,RASA1,RASGRP2,FGFR2,PHLPP2,ITPR1,NFKBIA,ARRB1,GRIN2D,JAK3 |
| 2.924e-06 | -12.74 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | 189 | 40 | 17758 | 1761 |
CDK17,FRMD4A,NFKBIE,FRMD6,KCTD12,GDF15,PHLDA1,STIL,TNFSF9,IER3,OTUD1,TNS3,SGK1,RAB20,PIM1,CITED2,TIPARP,SPRY2,C9orf72,TGIF1,RIPK2,PLSCR1,PLAUR,FURIN,FAM133B,DUSP4,RNF19B,FOS,ZFAND5,CDK5R1,CD83,MAPKAPK2,HLA-B,UAP1,PLK2,GEM,FZD5,TOB1,KLF7,EHD1 |
| 2.997e-06 | -12.72 | LINDGREN_BLADDER_CANCER_CLUSTER_2B | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 376 | 66 | 17758 | 1761 |
MYL9,DNAJC3,TSC22D3,LMCD1,COL18A1,IL27RA,SLC7A2,FAM46C,SH3KBP1,NOV,CTGF,DPYSL2,PIK3CD,TMTC1,TIMP2,COL6A2,TNS1,ZFAND5,EDNRA,SOCS3,HLF,LRIG1,NFKBIZ,RELL1,RUNX2,PCOLCE,NFKBIE,NUAK1,HLA-E,ARL4C,SELL,TGFBR1,DNAJB9,NRP2,SIRPA,BMP2K,CYR61,COL6A1,TPST1,UBE2J1,MYO5A,IGDCC4,AMOTL2,B3GNT2,ALDH2,TACC1,IFITM3,NR4A1,PLAUR,MPP1,TTC7A,STMN3,PRICKLE1,RUNX3,TCF7,NEURL1B,CRISPLD2,PITX2,RND3,NFKBIA,FHL1,GEM,ARPC2,JAK3,COL16A1,CYBRD1 |
| 3.015e-06 | -12.71 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | 196 | 41 | 17758 | 1761 |
GRN,LGALS3,CD63,BLVRB,CTSZ,F11R,BCAP31,LMNA,SGPL1,ARHGEF10L,APLP2,TNS3,RPS6KA2,CD9,DAPK1,CNNM4,CTTN,PTPRE,S100A13,SYK,LAMP2,GCA,ALDH2,MPP1,HSPA12A,CDA,HMG20B,TCF7,NPC2,SAV1,IDH1,POR,GABARAPL1,HLA-B,PRCP,SLC2A6,ZDHHC7,CLIP4,SLC27A3,RRAGD,CD33 |
| 3.062e-06 | -12.70 | cytoplasmic vesicle | cellular component | GO:0031410 | 1201 | 168 | 17570 | 1756 |
SUN1,LAMP1,KLK10,IL15RA,ATP8A1,HEXB,F11R,TGOLN2,SYTL4,PDGFB,ERP29,NCS1,SH3KBP1,DAPK2,AP1M2,STEAP2,ABCA2,RAB20,RP2,MARCH2,PACSIN1,MYRIP,SMAGP,LAMP3,LAMP2,SNTB2,ITCH,ARHGDIB,MCFD2,OPTN,DPYSL3,CXXC4,TRIM9,GPRC5B,DNM1L,WIPI1,KCNK1,ATP7B,RAB11FIP1,ARRDC1,PIK3C2B,ARF6,NRGN,PCSK5,PIFO,BMF,SERPINE2,HLA-E,HLA-F,RAB23,RAB6A,MARCH8,SNX18,RINL,ZNRF2,AHCY,CADPS2,HLA-C,PIKFYVE,WNT3A,GAD1,SYTL3,C9orf72,CCDC88A,CKAP4,GPR161,SNX7,KDELR1,C9orf9,KLK5,VEZT,ATP8B3,TP53INP2,C3orf58,STX3,GNAS,EPN3,AP1AR,TMEM30A,ITPR1,SH3BP4,KLK7,ATP1B3,PLD1,TMEM173,RUSC1,PROM2,PLA2G4A,SLC2A4,ERBB2,BCL2L1,PHLDA1,EMP2,BCAP31,SYTL2,APPBP2,PDGFA,ATP6V0B,N4BP3,DAB2IP,ECE1,RAB27B,LMAN1,PDIA6,DVL2,CHP1,MYO5B,CLCN3,SEC23A,FZD4,SEPT6,SLC11A2,RAB38,GABARAPL1,ATP1A1,STK26,SLC9A6,SYT13,ABCA1,ARFGEF3,ANXA3,GOLIM4,PACSIN2,SORT1,CD63,RUSC2,PDIA3,CTSZ,PKN1,HLA-A,FZD6,PDIA4,KIF5B,CTSC,CDK16,CD9,SGK3,ADAM15,IGFBP2,SYK,MYO5A,AMOTL2,SYPL1,RAB3B,ERMAP,RAPGEF2,SYBU,GRIN1,FURIN,GGH,COL7A1,FNDC3A,RNPEP,CRISPLD2,HLA-B,NUCB1,SERPINA1,FGFR2,RAB11FIP2,SCG2,SYT7,CTSV,ARRB1,ITGAV,GPER1,FZD5,TBC1D4,OCLN |
| 3.064e-06 | -12.70 | cellular component organization or biogenesis | biological process | GO:0071840 | 5468 | 641 | 16441 | 1675 |
ACACB,ADD1,MRPS15,AASS,AK7,HEXB,RET,CACNA2D2,NRG2,MORF4L2,SYTL4,CARD10,LTBP3,CALM2,WEE1,PSMD1,AP1M2,TUBG1,SEMA3G,TIAM1,DNAAF3,SPEF2,SMARCA2,CDA,MTRF1L,PRKAR2B,LOXL2,ICMT,ARF4,COL12A1,ABR,PLCG1,MID1IP1,DNM1L,LIMK1,TRAF3IP1,NOD2,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,SCN5A,ITGA6,SOX9,RAB23,GPSM2,MERTK,LMNA,ATG4A,ELF3,TFAP4,FRY,MEGF8,RIMS3,FLRT3,FAM13B,NEK2,ALPK1,PANX2,NCAM1,NUP85,PPP6R1,REC8,HPS3,KIF20A,PYM1,ERO1A,MYBL2,NPHP3,TP53INP2,PSMA4,PLIN5,PTPRF,NCOA3,TIMM8A,SEMA4D,SETD3,AURKA,CLMN,MDH1,NDE1,ARPC2,CFAP20,NUP58,MTM1,GRHL2,TMSB15A,ACTR8,PTTG1,C5orf30,PKP2,TESK2,NUF2,PRKACA,CCND1,CDH1,SP100,DACT1,ACSL4,DLG3,RASGEF1A,ETV4,SNX10,CAMSAP3,SSH3,SEC61B,COL6A2,FZD4,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,GTF2A2,SNX12,COX20,GABARAPL1,IRS2,PDLIM3,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,RGS14,MAPK12,TTC8,CTHRC1,SDC4,CTSZ,ANO9,PKN1,PLPPR4,ETS1,NEO1,DTX3L,ITGB8,IGSF9,CTSC,CST3,BAX,PLEKHF1,ADAM15,MAPK11,S100A6,CRTAP,ACBD5,PVRL4,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,RAPGEF2,GRIN1,UBE2A,CRISPLD2,CNTNAP1,RPL12,PLOD2,SYT7,NR4A3,ITGAV,CENPE,HMGA1,WDR45B,TLL2,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDC80,LMCD1,F11R,HDAC6,PDGFB,SDC1,SPTB,RPS6KA2,NPNT,SHC3,CNTRL,MITF,NTN4,TLN2,ANO4,TRAM1,NEB,ZNF462,PLK1,KCNIP3,ING1,CELSR2,CBX6,EZR,ARFRP1,ANLN,CDK1,OPTN,DPYSL3,KDM4D,DZIP1L,MSL1,MAP2,WIPI1,PRKCDBP,MYL12B,PRKAA2,LGALS3,HJURP,RASA2,PDCL,NCKAP1,CNTNAP2,FBLN1,IGF1R,TBCD,EXOC8,WNT3A,CYP26B1,DPYSL5,MRPS33,TESK1,RGMB,CORO2A,SPATA13,STRADB,SCRIB,CDK5R1,H1F0,PVRL2,COL13A1,ITGA7,ZDHHC7,LTBP2,ATP1B3,TMEM120A,CCNB2,SEMA3A,IFI6,NF2,P3H2,TP53,ERBB2,STIL,EMP2,BCAP31,TMSB15B,SYTL2,TTC21B,PDGFA,ATP6V0B,SRR,BCL6,ZDHHC23,PLK4,CDH3,ESPN,LMAN1,SULF2,CTH,SIRT1,PPIF,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,MYL12A,DAG1,TAPBP,IDE,RBL1,PTK7,ADAMTS14,EFNA5,SYT13,BIN1,COL9A3,PINK1,PACSIN2,KLHL13,CDCA8,ERI2,PSMD10,HMGN3,CRABP2,AIP,H1FX,NRP2,ZDHHC21,CDK16,SGK1,TRIM21,BUB1,ABCD1,HES1,FBLN5,RHOA,PSMB4,NR3C1,CRB3,AMFR,STMN3,COL7A1,BCAR1,BBS2,BORA,PRDX4,SERPINA1,FAT4,PGRMC1,PPP2R3C,SPCS3,TBC1D4,UBE2C,ARHGEF4,GOLGB1,DIS3L,SUN1,GAA,HSPG2,SSH1,ATP8A1,PSME1,PLXNA1,CCNB1,OAT,FAM101B,CENPN,TYMP,CTGF,ELMO2,PIK3CA,KCNS3,PACSIN1,XKR8,SPATA18,ACVR1C,PBK,CASP9,SLC35C1,KIF13A,TNS1,AGO4,PIF1,CCNF,MCFD2,ARHGEF26,PRIM1,SLC25A4,PLK2,GNPTAB,PRDM5,BMP1,UNC5B,F2RL1,FGD1,SEMA6B,MRPL44,TBC1D1,KIF23,SLC1A3,PSIP1,MECOM,DOPEY2,ITGA3,CYR61,SNX18,RPL39,PRKG1,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,EPB41L5,KCNJ12,PMPCB,DDB2,CALM1,ANO6,ATP8B3,EPHA1,JADE2,ANTXR1,NFIB,RASA1,STX3,FAS,DGKH,MMP15,PLEKHH2,PRKAG2,FAM64A,MATN2,FAM83D,FGD6,SFMBT1,KLK7,CABIN1,NR4A2,HOOK1,EHD1,SPRED1,SLC2A4,REPS2,TCTN2,DLGAP5,CEP70,TRIP10,ST14,RPS6KA1,IQGAP1,FTH1,KCTD12,BCL2L1,AIFM2,DDR1,MNS1,ZFYVE9,APLP2,DAB2IP,EPHB4,PDE4D,GPX4,SEMA3B,ATG4D,SEC23A,CAPN6,COG2,PRKCQ,SLC11A2,PKMYT1,PYGO1,ATP1B1,ITPR3,H2AFV,ALCAM,ATP10D,FZD7,NIN,CEP162,EPHA10,DDOST,JAK1,STK26,TRIOBP,NRG1,KLF5,MLKL,COBL,CBX7,WASF3,CENPI,ATP9A,EPS8,SPR,EFNB1,FGF19,SIX4,SLC25A36,SNTA1,PTEN,CD9,ATP8B1,ERBB3,SPRY2,NCOA2,FARP2,PDGFC,RASGRF1,B3GNT2,SHMT1,ARHGEF28,ZWINT,FURIN,DIAPH2,C1GALT1C1,YES1,KIF11,DCTN6,FGFR2,RYK,GRIN2D,GPER1,WDR62,NCAPG2,ARSB,ESPL1,OCLN,JARID2,RGMA,EMX1,CASP3,LTBP1,UGT8,MPP5,CACNB4,DNER,SH3KBP1,ZFYVE16,RAB15,LRRC6,DPYSL2,CEP78,DLG1,TRPC1,SUN3,RAB20,RP2,MYH14,CTTN,BTBD3,RASGRP1,CYP1B1,ATL1,CENPA,STRIP2,ARHGDIB,PTGFRN,MRPS36,TYSND1,CAPN1,NR2C2,PIFO,ARAP3,SERPINE2,BVES,PEX6,ETV5,CALM3,ADAMTSL4,KCNN4,COL6A1,FXYD5,LIMCH1,ZRANB1,SLC12A2,ALS2CL,CCDC88A,SNX7,VWA1,HMG20B,NUBP1,RANBP9,FECH,ONECUT1,UTP14C,TMEM30A,CDCA5,PITPNA,SHROOM2,JAK3,RARG,COL16A1,SNX30,KLF7,GAS2L1,DYNLRB1,LZTFL1,SORBS1,SPC25,PSME2,HDAC11,COL18A1,TDRKH,MRAS,KCTD9,SS18,SETDB2,ARTN,FRYL,KIF14,ZDHHC12,REEP1,RPN2,EPB41L4B,F2R,FRS3,CKS2,CHP1,GCA,ERBB2IP,CD40,KCTD2,ARHGAP35,JADE1,ALDH5A1,PEX2,SPTBN5,REEP4,LIFR,PPP2R2D,ABCA1,GCLM,FBLIM1,SORT1,ARHGEF11,TSPAN15,FRMD6,POC1B,CIT,LRP4,COL4A5,TGFBR1,HMGXB4,HDAC9,SAC3D1,KIF5B,TOP2A,TAF1B,ADORA1,LLGL2,A4GALT,BMP7,TOX2,IQGAP3,MYO5A,SUN2,RAB3B,CFAP46,GCLC,ASPM,CTSL,SWAP70,RND3,CTSV,SPINT2,RAP2C,ARRB1,GEM,PLOD3,CEP41,ZMIZ1,L1CAM,ABCG1 |
| 3.099e-06 | -12.68 | DH-domain | interpro domains | IPR000219 | 71 | 21 | 18293 | 1814 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,ARHGEF4,FGD1,FARP2 |
| 3.102e-06 | -12.68 | KIM_MYC_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_DN | 88 | 24 | 17758 | 1761 |
DDX58,LAMP1,GCA,RAB3B,LCA5,TTC39B,GRHL2,HMG20B,F11R,PIF1,NUCB2,DNER,OPTN,ELF3,DPYSL3,IL17RB,FAM111A,SCNN1A,CDH1,SHROOM3,KIF13B,PLEKHG1,KLF5,IFIH1 |
| 3.129e-06 | -12.67 | positive regulation of catabolic process | biological process | GO:0009896 | 367 | 66 | 16441 | 1675 |
DLGAP5,CNOT8,PSME2,CUL4B,PSME1,CCNB1,BARD1,APC2,BCAP31,IER3,PSMD1,DACT1,ZFP36,CDKN1B,DAB2IP,TWIST1,TIPARP,PLK1,SIRT1,TRIM8,AKT1,ITCH,CDC20,EZR,RNF19B,CDK1,IRS2,PLK2,NKD1,PRKAA2,TNRC6C,PINK1,SCOC,GGA1,DNAJB2,SOX9,ASB9,PSMD10,TRIB2,PPP2R3A,RNF128,CTSC,PTEN,BAX,SORL1,TRIM21,PLEKHF1,MYLIP,SOCS5,PSMB4,GCLC,NUB1,FURIN,PIP4K2C,PPARA,PRICKLE1,TP53INP2,PSMA4,PLIN5,GPLD1,SH3BP4,AURKA,UBE2C,NDFIP1,ESPL1,TOB1 |
| 3.186e-06 | -12.66 | GNF2_H2AFX | MSigDB lists | GNF2_H2AFX | 31 | 13 | 17758 | 1761 |
ZWINT,DLGAP5,FOXM1,ASPM,CDC20,PTTG1,CDCA8,AURKA,NUSAP1,CENPE,CCNF,CCNB2,CDK1 |
| 3.190e-06 | -12.66 | biological regulation | biological process | GO:0065007 | 11168 | 1219 | 16441 | 1675 |
HECA,HEXB,RET,ISOC2,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,HPCAL4,MARCH8,TFAP4,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,ALPK1,MYDGF,DGKG,MYLIP,NUP85,PPP6R1,PAQR7,PYM1,ERO1A,ELK1,NPHP3,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,INPP5D,CD82,PTTG1,GRK6,MGST2,MVB12B,ST5,CDH1,SH3BP1,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,SAT1,HTATIP2,GTF2A2,SNX12,ZNF618,NFIX,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,MAPK12,CTHRC1,TCAF1,CKAP2,ESRP1,SDC4,HABP4,BTN3A1,CTSZ,PLPPR4,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,FAM20B,CST3,BAX,IGFBP2,MED22,PARP9,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,CNTNAP1,RAB11FIP2,SYT7,DBI,NR4A3,ITGAV,OSR1,TMEM131,CCNI,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,NPNT,IL6ST,MITF,PASK,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,RINL,KIF13B,TBCD,SELK,PIM1,WNT3A,DPYSL5,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,FOXD2,RASGRP2,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,PTPRJ,IDE,ABHD12,RBL1,MMP17,STK38,EFNA5,IRF7,SYT13,ARFGEF3,BIN1,ZMAT1,PINK1,CPEB4,CDCA8,GTF3A,GDF15,HMGN3,AIP,PARM1,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,TSPAN13,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,PLAUR,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,SLC9A7,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,SLC35C1,LDB2,POR,PRIM1,ANKRD10,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,CDKN1C,SCOC,TBC1D1,THEMIS2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,RALGPS2,BHLHE41,VASN,PPP4R1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,CALM1,NPC2,EPHA1,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,TJP3,PELI2,FAM83D,SFMBT1,CABIN1,CDK18,KLK7,PER3,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,POPDC3,NGFRAP1,TSPAN18,TRIOBP,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,PBX3,HERC5,EFNB1,FGF19,HLA-A,ADGRB2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,RYK,ERAP1,LRRK1,FZD5,ESPL1,MELK,RGMA,CRYM,VARS2,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,ARHGEF37,SIVA1,TRPC1,CTTN,MYRIP,SP5,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,SUCO,HLA-C,C10orf54,ZRANB1,SLC12A2,GAD1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,LMO7,CCNE2,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,CKS2,PTPRU,GLO1,CD40,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,CIT,TGFBR1,TRIB2,SBF1,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,MYO5A,SYBU,RC3H2,RGCC,TTC7A,RUNX3,TCEAL8,FOXL1,LEPR,CTSL,ARHGAP24,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,PLOD3,AHR,RAB3IL1,CD33,ABCG1,ACACB,IL15RA,ADD1,DNAJC3,FBXO2,CACNA2D2,NRG2,IL18,SYTL4,MORF4L2,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CABP1,ALDH1A3,KLF3,ACOX2,PIK3CD,SEMA3G,APOBEC3G,ERAP2,SMARCA2,TNIP1,SH3BGRL,LOXL2,F12,ICMT,PPP1R14C,PGF,ANKRD6,DNM1L,LIMK1,AGFG2,SERPINB6,ARF6,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,SOX9,MERTK,LMNA,ELF3,FAM13B,NEK2,NCAM1,SLC37A1,SALL4,STAT4,MYBL2,TP53INP2,DCP2,STK17A,PTPRF,NCOA3,SEMA4D,SETD3,ITPR1,AURKA,MDH1,ARPC2,NDE1,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,ACTR8,RGS20,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,ARHGEF40,GSTP1,ETS1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,CXCL16,CTSC,TMBIM6,ADAM15,PLEKHF1,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,EIF5A2,GRIN1,NEURL1B,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,SIGIRR,TRIM2,CUL4B,EPHA4,NDC80,TP53I11,HDAC6,SDC1,PDGFB,SHC3,ELF5,DUSP10,ANO4,TLN2,MYBL1,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,WIPI1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,ITGA7,LTBP2,ATP1B3,IFI6,RNF146,AVPI1,UPF3B,NF2,FOXM1,P3H2,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,PLCG2,LHX6,EGLN3,SCN2A,GM2A,DVL2,CTH,SIRT1,TIMP2,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,AIFM3,ZNF701,PACSIN2,MACC1,ADGRG1,CD63,DAP,PSMD10,SELL,GABRG2,NKRF,CRABP2,SIRPA,SLC9A2,PPP2R3A,BUB1,KLF9,FAIM,TLE6,PSMB4,NR3C1,IFITM3,AMFR,PPARA,LITAF,PELI3,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,RGS3,ZFP36,IL31RA,STEAP2,ATRNL1,PACSIN1,RCAN3,XKR8,LAMP2,PBK,CASP9,NBPF3,AGO4,PIF1,CCNF,SAV1,SLC25A5,ZFAND5,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,NKD1,FAM110C,SARAF,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,ZNF84,MMD,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,RASA1,STX3,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,SLC4A3,TCEAL4,FGD6,NR4A2,MAP3K5,PLA2G4A,SLC2A4,ARMCX3,TRIP10,S100A11,NLRX1,RPS6KA1,CAST,IQGAP1,CD274,AIFM2,MNS1,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,NR2C1,MYO5B,CAPN6,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,APOBEC3H,SPR,LGALS3BP,TEAD3,SIX4,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,C1GALT1C1,GPLD1,NUCB1,GRIN2D,GPER1,ARSB,SLC25A38,CPEB2,JARID2,EXPH5,EMX1,CASP3,LTBP1,CAMKK1,CACNB4,DNER,DENND2D,KREMEN1,PTCHD4,SH3KBP1,NKAIN3,ARHGEF10L,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,SUN3,RAB20,RP2,MYH14,SLC39A10,PTPRE,RASGRP1,TRIM8,ASCL5,STRIP2,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,ADIPOR1,RAP1GAP,GRN,PIFO,LRRFIP2,PEX6,PHLPP1,ZNF432,CA2,KCNN4,DIAPH2-AS1,FXYD5,RFX5,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,GNAS,FECH,BCAR3,ONECUT1,NUDT16,PLPP3,CGREF1,CDCA5,NFKBIA,RHOBTB2,YOD1,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,SS18,SVBP,SETDB2,FRYL,TWIST1,GOT1,PDIA6,F2R,FRS3,MAP3K3,ZNF525,ERBB2IP,DUSP4,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,MIER3,AES,NOTUM,IRF2BPL,IL17RB,ADORA1,KIAA0319,IQGAP3,SUN2,RAB3B,GCLC,NR4A1,DEPDC4,ASPM,MBNL3,HLA-B,PRCP,DHRS2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 3.205e-06 | -12.65 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | 531 | 86 | 17758 | 1761 |
EXPH5,TRIM2,UGT8,TXN,CRYM,SLC25A13,MORF4L2,PJA2,OAT,KBTBD11,SDC1,CDS1,PLS3,EPCAM,APLP2,WEE1,CDH1,METTL7A,VAT1,GOT1,TECR,MINPP1,F2R,BTBD3,CTH,SEC23A,ACO1,PRKRA,H2AFV,IDH1,GABARAPL1,MFAP3L,ALDH5A1,SLC25A4,DDOST,DNM1L,SERPINI1,HSPB1,NR3C2,CDKN1C,ALDH6A1,FAM169A,ITGA6,DAP,EPS8,NCKAP1,PPP2R3A,DNAJB9,PARM1,SLC25A36,ADD3,CA2,IGF1R,CD9,TMBIM6,AHCY,IGFBP2,WWP1,ERBB3,ALDH3A2,IGSF3,FAH,SYPL1,PMPCB,PGM1,SHMT1,ALDH2,PIK3R1,FBXO9,AK4,GGH,YES1,FNDC3A,CYB5A,FECH,FUCA1,ACADSB,SLC4A4,NR1D2,SETD3,PGRMC1,ABCB1,CCDC69,MDH1,TOB1,OCLN |
| 3.212e-06 | -12.65 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 231 | 46 | 17758 | 1761 |
CCNE2,PRSS8,LTBP1,ARHGEF3,ENO2,EPHA4,EPS8,FAM198B,CRABP2,HERC6,DHRS3,PRKACA,FBLN1,PSIP1,HLA-A,CDKN2C,APOBEC3B,RAB15,GNB5,PLK4,ARVCF,IGFBP2,TINAGL1,CACNA1D,SMYD5,TIAM1,MAST4,SNX7,PLEKHA6,PLSCR1,IFITM3,MPP1,DUSP4,CDK1,ARHGAP35,NGFRAP1,PLOD2,PELI2,ITPR1,SIPA1L1,ANXA9,EPB41L4A,TRAF5,E2F8,CYBRD1,SNPH |
| 3.233e-06 | -12.64 | TIEN_INTESTINE_PROBIOTICS_24HR_UP | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_UP | 539 | 87 | 17758 | 1761 |
SPC25,DLGAP5,LGR4,FOXM1,ST14,CAST,SLC25A13,PTTG1,NDC80,MORC4,TGOLN2,PLXNA1,MGST2,SNN,CCNB1,OAT,CENPN,CMTM6,CCND1,ZFYVE16,APOBEC3B,PSMD1,KIF14,SIVA1,TUBG1,RP2,GM2A,CKS2,METAP2,PLK1,PPIF,CENPA,HTATIP2,NUSAP1,ARHGDIB,ATP1B1,ICMT,H2AFV,DAG1,SLC25A4,SLC9A6,MRPS28,ISOC1,NXT2,PACSIN2,HJURP,CENPI,ARL4C,ERI2,KIF23,ASAH1,HMGN3,NTAN1,SAC3D1,GNS,AIM1L,FAM111A,TNS3,CALD1,SGK1,ALDH7A1,BUB1,TAGLN2,FAIM,NUP85,TPCN1,HMMR,ZWINT,MMD,PRSS23,KIF20A,RAPGEF2,MRS2,FBXO9,GGH,KIF11,FRMD4B,ENDOD1,DCK,AMMECR1,DBI,TCEAL4,PPM1H,AURKA,TMEM14A,ESPL1,DOCK9 |
| 3.242e-06 | -12.64 | LEF1_UP.V1_UP | MSigDB lists | LEF1_UP.V1_UP | 183 | 39 | 17758 | 1761 |
PRKAA2,MYL9,WASF3,COL9A3,SCN5A,IGFBP6,KCTD12,ISYNA1,CRABP2,S100A2,HOXB2,ANO1,SCML1,PDGFA,KCNN4,BMP7,FJX1,COL6A1,PLEKHF1,APOBEC3G,CTH,KCNJ12,ELK3,NR3C1,S100A4,PLEKHO1,CDA,RUNX3,DHRS2,PELI2,AXL,PRKCDBP,FHL1,LTBP2,EPB41L4A,L1CAM,CYBRD1,PCSK5,RRAGD |
| 3.248e-06 | -12.64 | Signaling by EGFR | REACTOME pathways | R-HSA-177929 | 336 | 63 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,SH3KBP1,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SPRY2,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,LRIG1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 3.254e-06 | -12.64 | negative regulation of MAPK cascade | biological process | GO:0043409 | 140 | 33 | 16441 | 1675 |
SPRED1,PINK1,NF2,FOXM1,NDRG2,PSMD10,GSTP1,FBLN1,MECOM,IGF1R,DACT1,BMP7,RGS3,DLG1,DUSP10,SORL1,DAB2IP,SPRY2,AKT1,TNIP1,PBK,ITCH,EZR,DUSP4,RANBP9,DAG1,PTPRJ,STK38,ARRB1,GPER1,RGS14,F2RL1,HIPK3 |
| 3.267e-06 | -12.63 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 973 | 143 | 16441 | 1675 |
TXN,EPHA4,ARFGEF1,LMCD1,NRG2,PSME1,IL18,NENF,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,TSPAN6,IL31RA,AKR1B1,S100A13,RASGRP1,CYP1B1,TRIM8,PRKRA,CDK1,RHEB,PLCG1,GPRC5B,HPSE,DNM1L,ANKRD6,PLK2,MADD,FAM110C,NOD2,PRKCDBP,ADIPOR1,UNC5B,TRAF5,F2RL1,GAB1,RRAGD,BMF,RASA2,SOX9,CALM3,TNFRSF19,IL18R1,KIAA1161,IGF1R,PIK3AP1,MAP3K9,MDFIC,MYDGF,NCAM1,MDFI,CALM1,PDE5A,PSMA4,RASA1,FAS,GNAS,MAPKAPK2,SEMA4D,PELI2,CSF1,MAP3K5,JAK3,XDH,SPRED1,AVPI1,IL15,PSME2,TP53,ERBB2,BCL2L1,BCAP31,PDGFA,ST5,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,CTH,MAP3K3,SIRT1,TIMP2,RIPK2,FZD4,S100A4,PRKCQ,CD40,MAP3K6,FZD7,IRS2,PTPRJ,JAK1,AXL,SECTM1,NRG1,SPTBN5,NKX3-1,PINK1,ADGRG1,PSMD10,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BAX,SLC44A2,PLEKHF1,MAPK11,BUB1,ERBB3,IQGAP3,SYK,SPRY2,TRIM62,RASGRF1,HES1,RHOA,PSMB4,RAPGEF2,RC3H2,GRIN1,LITAF,BANK1,FGFR2,RYK,ARRB1,GRIN2D,LRRK1,GPER1,FZD5,NDFIP1,L1CAM |
| 3.283e-06 | -12.63 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 281 | 54 | 16441 | 1675 |
SPRED1,PSME2,RASA2,CALM3,PSMD10,ERBB2,NRG2,PSME1,ITPR2,NCKAP1,PDGFB,SPTB,FGF19,NRP2,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PIK3CA,DAB2IP,MAPK11,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,RHOA,AKT1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,ITPR3,BCAR1,PSMA4,RASA1,PGF,IRS2,MAPKAPK2,PLCG1,JAK1,FGFR2,AXL,ITPR1,NRG1,SPTBN5,GRIN2D,ITGAV,HSPB1,JAK3,MAPK12 |
| 3.301e-06 | -12.62 | Downstream signal transduction | REACTOME pathways | R-HSA-186763 | 322 | 61 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PHLPP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADRBK1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,PRKAR2B,DUSP4,ITPR3,BCAR1,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,PHLPP2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 3.307e-06 | -12.62 | cell part | cellular component | GO:0044464 | 15692 | 1622 | 17570 | 1756 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CARD10,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,MYDGF,PANX2,ZMYM1,DGKG,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,RAET1L,S100A5,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,DOCK9,TPRN,NQO1,INPP5D,CD82,PTTG1,C5orf30,MGST2,MVB12B,REPS1,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,TCAF1,CKAP2,ESRP1,DCAF7,SDC4,HABP4,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,PVRL4,OPLAH,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,PASK,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,ADCK5,RAB6A,HES2,NCKAP1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,SLC2A6,NLRC5,ZDHHC7,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,PTPRJ,IDE,ABHD12,RBL1,MMP17,STK38,EFNA5,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDH22,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,GDE1,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,SEMA6B,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,ST14,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,TRIQK,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,ADGRB2,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,SLC8B1,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,AFAP1,SNX30,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,LEPR,ARHGAP24,CTSL,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,UACA,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PQLC2,PSMD1,AP1M2,CABP1,CYP2S1,ALDH1A3,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,TIMM8A,SEMA4D,SETD3,ITPR1,AURKA,MDH1,MAL2,FBXO27,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,SYNE2,CYS1,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,TMA16,NUCB2,ETS1,GSTP1,ARHGEF40,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,GALNT3,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,UNKL,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,EPN3,COQ10A,H1F0,PVRL2,ITGA7,CSF1,MFSD2A,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,LHX6,PLCG2,N4BP3,SRR,SCN2A,MINPP1,EGLN3,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,TIMP2,MBP,EVA1A,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,BLVRB,GNE,SWI5,GABRG2,PSMD10,SELL,NKRF,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,IGDCC4,HMMR,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,FUCA1,SERPINA1,FAT4,ZNF214,NAT1,CDCA7L,NMI,NETO2,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,IQCE,ZFP36,RGS3,IL31RA,STEAP2,AOX1,PACSIN1,RCAN3,XKR8,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,PBK,CASP9,NBPF3,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,NKD1,FAM110C,DHTKD1,SARAF,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,MFI2,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,APLP2,ZNF75D,DOK4,CNNM4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,CSTF2,PGM2L1,GRIN2D,GPER1,ETAA1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,TMC1,TSEN34,SH3KBP1,ABCD4,CHPF,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,EDNRA,CXXC4,MDK,NEIL1,ZNF114,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,AMDHD1,GLCE,GNAS,FECH,XKRX,BCAR3,NUDT16,ONECUT1,SLC6A6,PLPP3,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SVBP,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,ARMC7,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,IL17RB,MDM1,ADORA1,MLPH,GALNS,CFAP43,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,DHRS2,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 3.329e-06 | -12.61 | organelle part | cellular component | GO:0044422 | 8026 | 892 | 17570 | 1756 |
ACACB,ADD1,IL15RA,MRPS15,AASS,SLC25A13,DNAJC3,HEXB,RET,FBXO2,DHX8,TGOLN2,MORF4L2,SYTL4,DPP8,BARD1,CALM2,DAPK2,WEE1,PQLC2,PSMD1,AP1M2,MUC4,UBE2T,CABP1,CYP2S1,FUT1,TUBG1,ACOX2,MGAT5,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,MTRF1L,TFAP2C,PRKAR2B,LOXL2,ICMT,CYP4F3,COL12A1,ENPP1,PLCG1,MID1IP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,HDAC1,MRPS28,TMOD2,ARF6,HSPB1,NXT2,SCN5A,FAM169A,ALDH6A1,GGA1,NUAK1,SOX9,RAB23,SLC36A4,COX6C,FAM21C,LMNA,MARCH8,GNS,FRY,ATP5H,FLRT3,RANBP1,NEK2,PCYOX1,CADPS2,MYDGF,NCAM1,NDUFA12,NUP85,C9orf72,PPP6R1,MCCC2,REC8,KIF20A,SALL4,STAT4,PYM1,ERO1A,MYBL2,ELK1,NPHP3,TP53INP2,SPTLC2,GNA11,PSMA4,SFXN5,DCP2,CYB5A,DHX32,SCARB2,NCOA3,ETS2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,GDF11,NDE1,ARPC2,CFAP20,NUP58,TMEM173,RUSC1,TPRN,MTM1,CCDC109B,GRHL2,GALNT12,ACTR8,C5orf30,RGS20,PKP2,TESK2,NUF2,MGST2,MVB12B,PRKACA,APC2,APPBP2,CDS1,CCND1,RCN1,MUC16,SCNN1A,CDH1,SP100,DACT1,XYLT2,ACSL4,ARL4D,RAB27B,CDKN2D,ZNF365,MYT1,ETV4,SNX10,TMEM9,MX1,CAMSAP3,SEC61B,COL6A2,FZD4,SEPT6,SYNE2,CYS1,HTATIP2,CDCA2,NUSAP1,DNAJB14,RAB38,XRCC6BP1,GTF2A2,COX20,GABARAPL1,PDLIM3,SHROOM3,WFS1,SLC9A6,PNPLA6,TRABD2A,RGS14,SLC25A30,MAPK12,TTC8,CKAP2,DCAF7,ESRP1,SDC4,HABP4,RASSF7,PDIA3,CTSZ,PKN1,TMA16,NUCB2,ETS1,SLC25A43,PDIA4,SGPL1,NEO1,CTNNBIP1,DTX3L,ADD3,FUT2,CTSC,ARSG,ANKS1B,CALD1,ALG13,MGAT4A,FAM20B,CST3,BAX,KLC3,PLEKHF1,ECI2,TMBIM6,MAPK11,TPCN1,S100A6,MED22,CRTAP,PARP9,ACBD5,LCA5,PLSCR1,TACC1,FMN1,BCL9,PIK3R1,EIF5A2,ELOVL3,MRS2,UBE2A,AK4,GALNT3,RPL12,PLOD2,RAB11FIP2,NR1D2,SYT7,DBI,NR4A3,CENPE,HMGA1,CMPK2,USF2,WDR45B,ACOT7,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDC80,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,HDAC6,PDGFB,NUP62CL,SDC1,SPTB,FANCI,PLS3,RPS6KA2,NPNT,CNTRL,SLC44A1,ABCA2,DUSP10,SCARA3,TRAM1,NEB,CCDC38,SMAGP,PLK1,THRB,PCGF5,ING1,STAU2,CBX6,NFE2L1,EZR,KLK6,ARFRP1,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,KDM4D,DZIP1L,HS6ST1,PLEKHG6,MSL1,AGPAT2,KLF12,MAP2,WIPI1,P4HA2,DOLPP1,ZNF367,RAB11FIP1,PIEZO1,MYL12B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,HJURP,LGALS3,CHCHD7,FXYD3,HLA-F,ASAH1,RAB6A,B4GALT4,DHRS3,B4GALNT1,DAZAP1,GATA2,KIF13B,TBCD,SELK,MDFIC,FAR2,WNT3A,MPHOSPH9,ALDH3A2,CKAP4,C9orf9,CYP26B1,CHSY3,MRPS33,MGAT4B,SPATA13,EMC2,SCRIB,TCF7,PDK3,G2E3,CDK5R1,MAPKAPK2,EPN3,COQ10A,H1F0,COL13A1,PHLPP2,MFSD2A,P4HA3,ZDHHC7,PLD1,TMEM120A,CCNB2,USP43,NF2,HOXB7,UPF3B,FOXM1,P3H2,XYLT1,TP53,ERBB2,FAM198B,LPIN3,STIL,EMP2,BCAP31,CYP26A1,TTC21B,PDGFA,ATP6V0B,WDR44,N4BP3,BCL6,PLK4,VAT1,ESPN,NOTCH3,OAS3,MINPP1,LMAN1,EGLN3,CTDSP2,GM2A,SULF2,CPD,PPIF,SIRT1,CLCN3,ERLEC1,EVA1A,AKT1,FIGNL1,COQ10B,CCSAP,CDC20,SERTAD3,MYL12A,DAG1,ATP13A2,TAPBP,DNAJC10,IDE,RBL1,STK38,IRF7,AIFM3,LTA4H,ST3GAL1,NDST3,ARFGEF3,MAN2B2,BIN1,COL9A3,CMAS,PINK1,PACSIN2,GOLIM4,CD63,BLVRB,SWI5,CDCA8,ERI2,PSMD10,GTF3A,HMGN3,NKRF,CRABP2,DSE,LBR,AIP,PARM1,VPS26A,DNAJB9,H1FX,FZD6,M6PR,ZDHHC21,CCDC92,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,BUB1,ALDH7A1,ABCD1,KLF9,GCNT1,HES1,RHOA,PSMB4,NR3C1,IFITM3,GUSB,AMFR,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,FNDC3A,BCAR1,BBS2,TXNDC11,MAPK8IP1,FUCA1,SERPINA1,CDCA7L,NMI,PGRMC1,PPP2R3C,SH3BGRL2,SPCS3,NDFIP1,UBE2C,TBC1D4,PTGES,HIPK3,ZBTB33,DIS3L,GOLGB1,SUN1,LAMP1,GAA,SLC35D2,TXN,SSH1,HSPG2,ATP8A1,TAP1,PSME1,CCNB1,PJA2,OAT,FAM101B,CENPN,NCS1,SLC9A7,CYP1A1,STIM1,RGS3,OSBPL3,STEAP2,IRF2,SNX16,HYLS1,MARCH2,ZBTB18,PACSIN1,LAMP2,LOC81691,KIFC2,SPATA18,SNTB2,SLC35C1,KIF13A,PIF1,GALNT7,CCNF,MCFD2,SLC25A5,POR,PRIM1,AHRR,SLC25A4,PLK2,GNPTAB,FAM110C,SARAF,TRAF5,MRPL44,SCOC,TMEM55B,HLA-E,DGKQ,SLC25A27,KIF23,NDUFA4,SLC1A3,PSIP1,KIAA1161,BMP2K,MECOM,DOPEY2,SNX18,ZNRF2,VASN,RPL39,BDH1,TPST1,SORL1,CACNA1D,PIKFYVE,GPR161,FAM69A,FADS2,DDB2,PMPCB,PRODH,B3GNT7,MMD,LPGAT1,CALM1,VEZT,ATP8B3,ANTXR1,JADE2,NFIB,DGKH,PLEKHH2,PRKAG2,FAM64A,FAAH,FAM83D,AGBL5,SFMBT1,NR4A2,CABIN1,PLIN3,MAP3K5,HOOK1,NRBP1,EHD1,PLA2G4A,SPRED1,SLC2A4,ARMCX3,CEP70,DLGAP5,TCTN2,NLRX1,TRIP10,THRA,RPS6KA1,IQGAP1,CCDC110,ATP2C2,BCL2L1,SNN,AIFM2,CYP39A1,MNS1,ZFYVE9,ACAP2,CDKN1B,PDE4D,LGMN,TSPAN1,NR2C1,MED30,GPX4,ATG4D,MYO5B,DOCK4,SEC23A,COG2,CAPN6,FOXJ2,LYRM1,UTRN,KIF1C,SLC11A2,RAD17,PKMYT1,PYGO1,ITPR3,H2AFV,TRIQK,ATP10D,SP4,NIN,CEP162,DDOST,PPP2R5A,STK26,TRIOBP,SLC27A1,KLF5,HS3ST3B1,SLC27A3,NR3C2,COBL,CBX7,DEPDC1,ATP9A,CENPI,EPS8,FBXO6,SPR,DNAH3,TEAD3,HLA-A,SLC25A36,AKIRIN1,FAM111A,PHF7,PTEN,FUT8,DRAM1,CD9,ATP8B1,SLC44A2,CITED2,CNPY3,SPRY2,NCOA2,PDGFC,TGIF1,ZWINT,B3GNT2,ALDH2,ZC3H11A,MPP1,FURIN,PARP4,C1GALT1C1,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,GPLD1,DCTN6,NUCB1,ACADSB,FGFR2,CSTF2,ERAP1,GPER1,WDR62,FZD5,ARSB,NCAPG2,SLC25A38,ESPL1,ESYT2,JARID2,CASP3,CRYM,CPT2,MPP5,SLC8B1,ERP29,TMC1,TRIM68,TSEN34,SH3KBP1,ABCD4,CHPF,ZFYVE16,RAB15,GRHL1,ZCCHC12,SIVA1,DPYSL2,CEP78,PHTF1,DLG1,AKR1B1,TRPC1,ANKRD12,SUN3,RAB20,RP2,MYH14,CTTN,TECR,MYRIP,RASGRP1,LAMP3,CYP1B1,ATL1,TRIM8,CENPA,PTGFRN,MRPS36,MAN2A2,NEIL1,GPRC5B,HPSE,GLA,NRGN,RAP1GAP,NR2C2,PCSK5,STARD3NL,LASP1,PIFO,PEX6,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,LRIF1,ETV7,GAD1,SNX7,TPGS2,KDELR1,ELK3,OXR1,GYLTL1B,HMG20B,PDIK1L,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,GLCE,FECH,GNAS,NUDT16,UAP1,PLPP3,UTP14C,TMEM30A,CDCA5,CTSA,SHROOM2,APOL2,COL16A1,RARG,PROM2,GAS2L1,CCNE2,DYNLRB1,SLC25A24,SORBS1,SPC25,IL15,PSME2,HDAC11,PDIA5,MORC4,COL18A1,PHLDA1,LRRC45,SLC25A48,SS18,SETDB2,CYP4F11,KIF14,REEP1,RPN2,ECE1,PDIA6,SEPHS1,CHP1,SLC39A8,OSTM1,C3orf52,ERBB2IP,DUSP4,FANCE,CASP4,JADE1,ALDH5A1,BFSP1,PEX2,TLE1,SPTBN5,CYP2U1,REEP4,GLIS3,ANXA3,FBLIM1,SORT1,POC1B,COL4A5,INTS8,POMGNT1,HMGXB4,HDAC9,SAC3D1,TMEM63A,IRF2BPL,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,GALNS,RRBP1,TOX2,KIAA0319,CLIP2,MYO5A,B3GALT6,SUN2,SYPL1,RAB3B,CFAP46,ASPM,NR4A1,RC3H2,SYBU,RGCC,OGDHL,RUNX3,CTSL,HLA-B,RND3,TRIM69,DHRS2,HNRNPH2,CTSV,RAP2C,ARRB1,MCUR1,HOXB13,GEM,SOX8,PLOD3,CEP41,ZMIZ1,AHR,ABCG1,SNPH |
| 3.355e-06 | -12.60 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | 190 | 40 | 17758 | 1761 |
SUN1,TXN,DLGAP5,LGALS3,GNPDA1,DAP,LACTB2,MNS1,REPS1,KCTD9,TOP2A,CDKN2C,PLK4,CD9,BUB1,SNX10,LAMP2,CENPA,PQLC3,SH3BGRL,S100A4,CDC20,LITAF,NUSAP1,CCNF,ZFAND5,IDH1,KIF11,CDK1,PSMA4,GABARAPL1,CARHSP1,IDE,TWSG1,CORO1C,CDCA5,DBI,HDAC1,GEM,CCNB2 |
| 3.371e-06 | -12.60 | cell surface | cellular component | GO:0009986 | 719 | 110 | 17570 | 1756 |
LAMP1,BCAM,SLC2A4,NF2,SSH1,IL15,EPHA4,CD274,PDGFB,SDC1,ERP29,EMP2,TMC1,SPTB,PDGFA,EPCAM,SCNN1A,IL6ST,PLK4,ECE1,F2R,SULF2,CLCN3,CD55,TIMP2,FZD4,SEPT6,CR2,TNS1,SLC11A2,CD40,ALCAM,PTGFRN,ENPP1,PLEKHG6,PTPRJ,IDE,GPRC5B,AXL,NOD2,EFNA5,NRG1,ANXA9,ARF6,ABCA1,GRN,SCN5A,SORT1,LGALS3,SERPINE2,CD63,TSPAN15,ITGA6,HLA-F,HLA-E,LRP4,SDC4,PDIA3,SELL,SLC1A3,CNTNAP2,PKN1,PLPPR4,ANO1,SRPX2,HLA-A,FZD6,PDIA4,CD109,IL17RB,ITGA3,ITGB8,ALPP,VASN,CD9,ADAM15,TNFRSF12A,C10orf54,HLA-C,NCAM1,WNT3A,ULBP2,IGSF3,HMMR,PDGFC,RHOA,MFI2,MICB,ANO6,RC3H2,GRIN1,FURIN,ANTXR1,FAS,CD83,HLA-B,FGFR2,PVRL2,ACVRL1,ITGA7,CTSV,ABCB1,ITGAV,NDE1,FZD5,ARSB,L1CAM,CD33,ABCG1,PROM2 |
| 3.386e-06 | -12.60 | TSENG_IRS1_TARGETS_DN | MSigDB lists | TSENG_IRS1_TARGETS_DN | 131 | 31 | 17758 | 1761 |
SGCE,RAB3B,CAPN6,CD63,THRA,FRMD6,LITAF,FTH1,CD40,SNTB1,SESN1,EFNB1,MESDC2,CDKN2C,B3GALNT1,TAPBP,ENPP1,CARHSP1,POPDC3,GNPTAB,IL6ST,TSPAN6,CST3,COL6A1,ITPR1,LIMCH1,PHKA2,LIFR,CTDSP2,CCDC88A,FAH |
| 3.418e-06 | -12.59 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 37 | 17758 | 1761 |
BIN1,SIGIRR,CKAP2,UBASH3B,ITGA6,EPHA4,ASAH1,F11R,DNAJB9,C16orf74,OTUD1,FAM111A,SORL1,PIM1,PDE4D,MYLIP,C9orf72,SMAGP,SUSD3,KIFC2,ITCH,COQ10B,UTRN,DIAPH2,FOS,GABARAPL1,RASGRP2,SOCS3,IRS2,NR1D2,PELI2,NR4A2,NFKBIZ,KLF11,TOB1,MAFF,PCSK5 |
| 3.418e-06 | -12.59 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | 170 | 37 | 17758 | 1761 |
SIGIRR,NUAK1,TRIP10,CTDSPL,ERBB2,KCTD12,SLC1A3,CRABP2,TRIB2,SDC1,FBLN1,ARHGEF40,CCND1,APLP2,LHX6,RRBP1,CNNM4,EPHB4,SCARA3,NCOA2,CRTAP,SEMA3B,CYP26B1,OPLAH,FZD4,PTGER4,DUSP4,STEAP1,GLT8D2,FZD7,FAT4,PLK2,PGRMC1,BMP1,INPP4B,REEP4,EHD1 |
| 3.453e-06 | -12.58 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 355 | 63 | 17758 | 1761 |
GAS2L1,FBLIM1,CCDC109B,KLK10,TTC39B,CPEB4,IGFBP6,NLRX1,FRMD6,TEX2,IL13RA1,HES2,SDC1,S100A2,CARD10,TMCC3,PLS3,AIM1L,UBE2Q2,AP1M2,ARHGEF37,SLC44A1,KLC3,SERINC2,ARL4D,EGLN3,ULBP2,MAST4,ALS2CL,GM2A,S100A6,ERAP2,MYO5A,PVRL4,FAM160A1,OSTM1,PLAUR,UBE2A,PIP4K2C,EZR,MTRF1L,RAB38,PTGFRN,CASP4,ARF4,STK17A,CARHSP1,HPSE,C19orf66,CORO1C,P4HA2,INPP4B,BMP1,OVOL1,ADAMTS14,KLK7,NRG1,PLIN3,TANC2,SERPINB1,DCBLD1,KLF7,EHD1 |
| 3.473e-06 | -12.57 | cell | cellular component | GO:0005623 | 15728 | 1625 | 17570 | 1756 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CARD10,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,CLDN4,CRY2,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,MYDGF,PANX2,ZMYM1,DGKG,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PCTP,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,RAET1L,S100A5,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,DOCK9,TPRN,NQO1,INPP5D,CD82,PTTG1,C5orf30,MGST2,MVB12B,REPS1,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,TCAF1,CKAP2,DCAF7,ESRP1,SDC4,HABP4,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,PVRL4,OPLAH,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,PASK,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,ADCK5,RAB6A,HES2,NCKAP1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,SLC2A6,NLRC5,ZDHHC7,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,WDR44,LMO4,BCL6,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,PTPRJ,IDE,RBL1,ABHD12,MMP17,STK38,EFNA5,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDH22,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,LGR4,HSPG2,VANGL1,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,GDE1,PRDM5,BMP1,NFKBIZ,WBSCR27,F2RL1,FGD1,SEMA6B,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,AGBL5,FAM83D,SFMBT1,CABIN1,KLK7,PLIN3,PER3,HOOK1,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,ST14,THRA,DDIT4L,RALBP1,CCDC110,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,TRIQK,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,ADGRB2,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,SLC8B1,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,RARG,SNX30,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,CLIP2,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,RGCC,NADK2,TTC7A,RUNX3,TCEAL8,FOXL1,LEPR,ARHGAP24,CTSL,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,UACA,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PQLC2,PSMD1,AP1M2,CABP1,CYP2S1,ALDH1A3,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,RELL1,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,TIMM8A,SEMA4D,SETD3,ITPR1,AURKA,MDH1,MAL2,FBXO27,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,SYNE2,CYS1,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,TMA16,NUCB2,ETS1,GSTP1,ARHGEF40,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,GALNT3,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,UNKL,TRIM2,GNPDA1,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,DDX59,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,EPN3,COQ10A,H1F0,PVRL2,ITGA7,CSF1,MFSD2A,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,LHX6,PLCG2,N4BP3,SRR,SCN2A,MINPP1,EGLN3,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,TIMP2,MBP,EVA1A,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,ADGRG1,RUSC2,BLVRB,GNE,SWI5,GABRG2,PSMD10,SELL,NKRF,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,CCDC92,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,IGDCC4,HMMR,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,CD83,FUCA1,SERPINA1,FAT4,ZNF214,NAT1,CDCA7L,NMI,NETO2,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,IQCE,ZFP36,RGS3,IL31RA,STEAP2,AOX1,PACSIN1,RCAN3,XKR8,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,PBK,CASP9,NBPF3,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,GNPTAB,NKD1,FAM110C,SARAF,DHTKD1,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,IGSF3,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,MMD,ZNF84,MFI2,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,CEP70,ARMCX3,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,APLP2,ZNF75D,DOK4,CNNM4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,WASF3,NUDT6,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,TEAD3,SIX4,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,CSTF2,PGM2L1,GRIN2D,GPER1,ETAA1,ARSB,NCAPG2,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,HEBP1,CACNB4,DNER,DENND2D,TMC1,TSEN34,SH3KBP1,ABCD4,CHPF,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,EDNRA,CXXC4,MDK,NEIL1,ZNF114,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,AMDHD1,GLCE,GNAS,FECH,XKRX,BCAR3,NUDT16,ONECUT1,SLC6A6,PLPP3,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SVBP,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,ARMC7,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,IRF2BPL,IL17RB,MDM1,ADORA1,MLPH,GALNS,CFAP43,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,DHRS2,PRCP,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 3.519e-06 | -12.56 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 157 | 35 | 17758 | 1761 |
PCOLCE,DLGAP5,SPC25,PTTG1,TMX4,KIF23,HMGN3,H1FX,HDAC9,TOP2A,RPS6KA2,METTL7A,DOK4,SORL1,TWIST1,ALDH7A1,BUB1,SPRY2,GM2A,IGSF3,NFE2L3,PLK1,HMMR,CENPA,S100A4,CDC20,AK4,H2AFV,NFIB,CDK1,CYB5A,DBI,AURKA,UBE2C,ESPL1 |
| 3.564e-06 | -12.54 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | 125 | 30 | 17758 | 1761 |
CCNE2,CASP3,TIMP2,PLAUR,LITAF,TP53,ERBB2,AK4,MGST2,CCNB1,GSTP1,CDK1,FAS,WEE1,BTG3,TIMP3,CDH1,PTEN,SHC3,IL6ST,NFKBIA,MAP3K9,BAX,DAPK1,CDKN1B,TNFRSF12A,IGFBP2,ERBB3,HSPB1,CCNB2 |
| 3.566e-06 | -12.54 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 572 | 91 | 17758 | 1761 |
SPRED1,TRIM2,NF2,TRIP10,TSC22D3,RET,MRAS,SLC7A2,CARD10,NCS1,WEE1,SIPA1L2,ELMO2,VAT1,SNX16,ACSL4,EPB41L4B,PDIA6,SMYD5,TRAM1,CPD,MAP3K3,PCGF5,CAPN6,SNTB2,SESN1,COL12A1,DOLPP1,SLC9A6,LRIG1,CAB39,PIEZO1,ISOC1,CDK17,SCOC,LRRFIP2,DCAF7,FAM134A,PBX3,KIF23,FAM81A,SIX4,NRP2,KIF5B,IRF2BPL,TFAP4,E2F7,TMEM87B,BHLHE41,MGAT4A,KCNN4,UBE2J1,TFAP2A,SGK1,WWP1,C8orf58,PIM1,C10orf54,WNT3A,SLC12A2,SYPL1,PHF20L1,MMD,PIK3R1,GRIN1,ZKSCAN2,LITAF,FURIN,STRADB,AK4,FAM133B,EPHA1,PDIK1L,SFXN5,CDK5R1,SLC4A4,RAB11FIP2,SETD3,PHLPP2,KBTBD2,CSNK1G1,AMMECR1,ITPR1,RAP2C,NR4A3,PITPNA,SH3BGRL2,YOD1,HMGA1,ARHGEF9,CPEB2 |
| 3.570e-06 | -12.54 | Extracellular matrix organization | REACTOME pathways | R-HSA-1474244 | 267 | 53 | 8202 | 867 |
CASP3,LTBP1,COL9A3,PCOLCE,HSPG2,P3H2,ITGA6,LRP4,SDC4,COL18A1,COL4A5,F11R,SDC1,DDR1,FBLN1,PDGFB,LTBP3,PDGFA,ITGA3,ITGB8,CDH1,BMP7,COL6A1,ADAM15,NTN4,NCAM1,CRTAP,ADAMTS2,FBLN5,TIMP2,COL6A2,FURIN,COL7A1,LOXL2,DAG1,COL12A1,CTSL,MMP15,COL13A1,PLOD2,ITGA7,MMP17,CTSV,BMP1,ADAMTS14,KLK7,LTBP2,ITGAV,PLOD3,COL16A1,CAPN1,TLL2,ADAMTS16 |
| 3.574e-06 | -12.54 | JEON_SMAD6_TARGETS_DN | MSigDB lists | JEON_SMAD6_TARGETS_DN | 19 | 10 | 17758 | 1761 |
IRS2,TOP2A,CENPA,CDH1,KIF23,NOTCH3,ERBB3,CCNB2,KIF11,CTH |
| 3.584e-06 | -12.54 | E2F3_UP.V1_UP | MSigDB lists | E2F3_UP.V1_UP | 177 | 38 | 17758 | 1761 |
CCNE2,UGT8,ENO2,FAM92A1,CDKN1C,LRP4,ABCG2,CYP26A1,SAC3D1,IL17RB,CDKN2C,LRRC45,E2F7,ZDHHC12,REEP1,ZDHHC23,KCNS3,ATRNL1,SNX10,TIAM1,GAD1,RASGRP1,FBXL16,MICB,CDK5R1,CD83,MMP15,CDK19,DCK,HOXA9,ZNF367,SLC4A3,RHOBTB2,TMOD2,CMPK2,SLC27A3,EGLN1,RRAGD |
| 3.587e-06 | -12.54 | ONDER_CDH1_TARGETS_2_UP | MSigDB lists | ONDER_CDH1_TARGETS_2_UP | 246 | 48 | 17758 | 1761 |
MYL9,CCNE2,BIN1,LTBP1,PCOLCE,ALDH6A1,ENO2,REPS2,ZCCHC24,TSC22D3,EPS8,LMCD1,SLC7A2,ARHGEF40,FBLN1,CCDC92,CDKN2C,RPS6KA2,MLPH,CTGF,COL6A1,MITF,AOX1,SRR,TWIST1,KLF9,CITED2,MYBL1,CYP1B1,TRAK2,DOCK4,COL6A2,FBLN5,SEPT6,PTGER4,ROR1,LEPR,DPYSL3,ENPP1,FAT4,WIPI1,PLOD2,ITGA7,LRIG1,PPM1H,LTBP2,SHROOM2,CYBRD1 |
| 3.594e-06 | -12.54 | regulation of cyclin-dependent protein kinase activity | biological process | GO:1904029 | 122 | 30 | 16441 | 1675 |
PLK1,CCNE2,CASP3,CDKN1C,AKT1,DNAJC3,RGCC,HERC5,PSMD10,PKMYT1,TRIB2,PDGFB,STIL,MAPK8IP1,CDK5R1,SOCS3,CCND1,TFAP4,CDKN2C,CDK5RAP1,DIRAS3,PTEN,CDKN1B,PIM1,CDKN2D,UBE2C,PKIA,SOCS5,CKS2,CHP1 |
| 3.615e-06 | -12.53 | REACTOME_AXON_GUIDANCE | MSigDB lists | REACTOME_AXON_GUIDANCE | 239 | 47 | 17758 | 1761 |
MYL9,COL9A3,SCN5A,ARHGEF11,RPS6KA1,ERBB2,COL4A5,PLXNA1,CACNB4,SPTB,NRP2,NEO1,RPS6KA2,ARTN,DPYSL2,COL6A1,DLG1,NTN4,MYH14,SCN2A,NCAM1,DLG3,FARP2,DPYSL5,COL6A2,RHOA,RGMB,EZR,PRKCQ,ALCAM,CDK1,RANBP9,CDK5R1,DPYSL3,ARHGAP35,CNTNAP1,PLCG1,SEMA4D,LIMK1,PITPNA,SPTBN5,ITGAV,UNC5B,SEMA3A,L1CAM,MYL12B,RGMA |
| 3.714e-06 | -12.50 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1133 | 162 | 16441 | 1675 |
UGT8,SSH1,NRG2,F11R,PSME1,ITPR2,PDGFB,SPTB,CALM2,ZFYVE16,PSMD1,CTGF,SHC3,ZCCHC12,KLF3,FOSB,PIK3CA,AKR1B1,PIK3CD,RASGRP1,THRB,CASP9,EZR,AGO4,PRKAR2B,POR,RHEB,ENPP1,PLCG1,NOD2,CAB39,HDAC1,EIF4EBP2,ADIPOR1,GAB1,NR2C2,RRAGD,PRKAA2,RUNX2,RASA2,SOX9,CALM3,PHLPP1,TFAP4,IGF1R,MEGF8,FLRT3,COL6A1,C10orf54,NCAM1,PAQR7,EPB41L5,RGMB,CALM1,STRADB,ELK1,PSMA4,RASA1,GNAS,FECH,NCOA3,PRKAG2,PHLPP2,ITPR1,SH3BP4,NR4A2,LTBP2,JAK3,COL16A1,RARG,EHD1,GAS2L1,SPRED1,SORBS1,SLC2A4,THRA,IQGAP1,PSME2,TP53,ERBB2,BCL2L1,PRKACA,ZFYVE9,PDGFA,ATP6V0B,ACAP2,CDH1,CDKN1B,DAB2IP,GOT1,PDE4D,RASGEF1A,NR2C1,FRS3,AKT1,RIPK2,ITPR3,CASP4,SOCS3,IRS2,IDE,ATP1A1,JAK1,RBL1,SLC27A1,NRG1,SPTBN5,NR3C2,TNRC6C,NKX3-1,SORT1,CPEB4,LRP4,PSMD10,GABRG2,TGFBR1,GDF15,FGF19,HDAC9,ADRBK1,PTEN,BMP7,FUT8,CD9,IGFBP2,KLF9,ERBB3,SYK,SPRY2,MYO5A,NCOA2,PDGFC,TGIF1,RASGRF1,RHOA,SHMT1,PSMB4,NR3C1,RAPGEF2,NR4A1,PIK3R1,GRIN1,FURIN,PPARA,YES1,FOS,BBS2,BCAR1,GPLD1,CTSL,PLOD2,ACVRL1,NR1D2,TWSG1,FGFR2,NR4A3,GRIN2D,GPER1,PLOD3,TBC1D4,CPEB2,RGMA |
| 3.739e-06 | -12.50 | regulation of cellular process | biological process | GO:0050794 | 10106 | 1114 | 16441 | 1675 |
HECA,HEXB,RET,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,ITGA6,RAB23,GPSM2,FAM21C,HPCAL4,TFAP4,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,MYDGF,DGKG,MYLIP,NUP85,PPP6R1,PAQR7,PYM1,ERO1A,ELK1,NPHP3,PSMA4,GNA11,PLIN5,ETS2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,INPP5D,CD82,PTTG1,GRK6,MVB12B,ST5,CDH1,SH3BP1,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,SAT1,HTATIP2,GTF2A2,SNX12,ZNF618,NFIX,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,TCAF1,CKAP2,ESRP1,SDC4,HABP4,BTN3A1,PLPPR4,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,FAM20B,CST3,BAX,IGFBP2,MED22,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,CNTNAP1,SYT7,DBI,NR4A3,ITGAV,OSR1,CCNI,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,NPNT,IL6ST,MITF,PASK,ABCA2,SCARA3,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,MYL12B,RRAGD,RUNX2,LMTK3,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,KIF13B,TBCD,SELK,PIM1,WNT3A,DPYSL5,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,FOXD2,RASGRP2,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,PTPRJ,IDE,RBL1,STK38,EFNA5,IRF7,SYT13,ARFGEF3,BIN1,ZMAT1,PINK1,CPEB4,CDCA8,GTF3A,GDF15,HMGN3,AIP,PARM1,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,TSPAN13,SYK,WBP5,NFE2L3,HES1,FBLN5,RHOA,PLAUR,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,SLC35C1,LDB2,POR,ANKRD10,PRDM5,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,CDKN1C,SCOC,TBC1D1,THEMIS2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,RALGPS2,BHLHE41,VASN,PPP4R1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,CALM1,NPC2,EPHA1,ANTXR1,NFIB,AP1AR,PLEKHH2,TJP3,PELI2,FAM83D,SFMBT1,CDK18,CABIN1,PER3,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,FTH1,BCL2L1,DDR1,ZFYVE9,EPS8L2,APOBEC3B,NOV,PDE4D,EPHB4,TSPAN1,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,FZD7,NGFRAP1,TSPAN18,TRIOBP,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,HERC5,PBX3,EFNB1,FGF19,ADGRB2,HLA-A,WWP2,SCML1,RASSF8,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,PDGFC,TGIF1,ZWINT,ARHGEF28,ZKSCAN2,FBXO9,DIAPH2,YES1,FOS,KIF11,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,LRRK1,FZD5,ESPL1,MELK,RGMA,CRYM,VARS2,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,ARHGEF37,SIVA1,TRPC1,CTTN,MYRIP,SP5,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,SUCO,C10orf54,HLA-C,ZRANB1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,NUBP1,C3orf58,RANBP9,SOX13,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,CCNE2,LMO7,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,CKS2,PTPRU,GLO1,CD40,CASP4,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,CIT,TGFBR1,TRIB2,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,MYO5A,SYBU,RC3H2,RGCC,RUNX3,TCEAL8,LEPR,FOXL1,CTSL,ARHGAP24,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,AHR,CD33,ABCG1,ACACB,IL15RA,ADD1,DNAJC3,FBXO2,CACNA2D2,NRG2,IL18,SYTL4,MORF4L2,BARD1,CA8,DAPK2,CALM2,WEE1,PSMD1,CABP1,ALDH1A3,KLF3,PIK3CD,SEMA3G,APOBEC3G,SMARCA2,TNIP1,SH3BGRL,LOXL2,F12,ICMT,PPP1R14C,PGF,ANKRD6,DNM1L,LIMK1,SERPINB6,ARF6,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,SOX9,MERTK,LMNA,ELF3,FAM13B,NEK2,NCAM1,SALL4,STAT4,MYBL2,TP53INP2,STK17A,PTPRF,NCOA3,SEMA4D,SETD3,ITPR1,AURKA,ARPC2,NDE1,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,GRHL2,ACTR8,RGS20,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,ARHGEF40,GSTP1,ETS1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,CXCL16,CTSC,TMBIM6,ADAM15,PLEKHF1,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,FMN1,BCL9,RAPGEF2,EIF5A2,GRIN1,NEURL1B,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,MYL9,SIGIRR,TRIM2,CUL4B,EPHA4,NDC80,TP53I11,HDAC6,SDC1,PDGFB,SHC3,ELF5,DUSP10,MYBL1,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,WIPI1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,ITGA7,LTBP2,ATP1B3,IFI6,RNF146,AVPI1,UPF3B,NF2,FOXM1,P3H2,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,LHX6,PLCG2,EGLN3,SCN2A,DVL2,CTH,SIRT1,TIMP2,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,AIFM3,ZNF701,PACSIN2,MACC1,ADGRG1,CD63,DAP,PSMD10,SELL,GABRG2,NKRF,CRABP2,PPP2R3A,BUB1,KLF9,FAIM,TLE6,PSMB4,IFITM3,NR3C1,AMFR,PPARA,LITAF,PELI3,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,PPP4R4,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,RGS3,ZFP36,IL31RA,ATRNL1,PACSIN1,RCAN3,PBK,CASP9,NBPF3,AGO4,PIF1,SAV1,CCNF,SLC25A5,ZFAND5,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,NKD1,FAM110C,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,HLA-E,DGKQ,SLC25A27,KIF23,SLC1A3,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EPB41L5,MFI2,MMD,ZNF84,MICB,ANO6,AMER1,PIP4K2C,RASA1,STX3,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,TCEAL4,FGD6,NR4A2,MAP3K5,PLA2G4A,ARMCX3,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,CD274,AIFM2,MNS1,APLP2,ZNF75D,DOK4,CDKN1B,DAB2IP,IFIT1,LGMN,NR2C1,CAPN6,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,NR3C2,WASF3,PCOLCE,ARHGEF3,ARL4C,APOBEC3H,LGALS3BP,SIX4,TEAD3,SNTA1,FAM111A,PTEN,SGK3,SLC44A2,ATP8B1,CNOT6L,CNPY3,TRIM62,SPRY2,OSGIN1,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,GPLD1,NUCB1,GRIN2D,GPER1,ARSB,CPEB2,JARID2,EXPH5,EMX1,CASP3,LTBP1,CAMKK1,DNER,CACNB4,KREMEN1,SH3KBP1,PTCHD4,ARHGEF10L,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,RAB20,MYH14,SLC39A10,PTPRE,RASGRP1,TRIM8,ASCL5,STRIP2,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,ADIPOR1,RAP1GAP,GRN,PIFO,LRRFIP2,PHLPP1,ZNF432,CA2,KCNN4,DIAPH2-AS1,FXYD5,RFX5,LRIF1,ALS2CL,OXR1,HMG20B,BCAR3,GNAS,FECH,ONECUT1,NUDT16,PLPP3,CGREF1,CDCA5,NFKBIA,RHOBTB2,YOD1,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,ARHGEF16,SS18,SVBP,SETDB2,FRYL,TWIST1,GOT1,PDIA6,F2R,FRS3,MAP3K3,ZNF525,ERBB2IP,DUSP4,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,LRP4,MIER3,AES,NOTUM,IL17RB,IRF2BPL,ADORA1,KIAA0319,IQGAP3,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,MBNL3,HLA-B,PRCP,DHRS2,HOXB13,GEM,SOX8,L1CAM |
| 3.761e-06 | -12.49 | HELLER_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_UP | 275 | 52 | 17758 | 1761 |
DDX58,PACSIN2,NQO1,IL15,FOXM1,TSPAN15,ARL4C,DHX8,IL13RA1,CNTNAP2,GPSM2,SNN,CCNB1,HERC6,BMP2K,SIRPA,IER3,TOP2A,CDH1,METTL7A,DOK4,BCL6,BUB1,IFIT1,PIK3CD,CLIP2,S100A13,APOBEC3G,S100A6,CYP1B1,LAMP3,MX1,PLK1,ALDH2,S100A4,USP18,CDC20,SAT1,PTGER4,CCNF,IFIT3,RNF19B,ALCAM,MAP3K6,ATP13A2,SOCS3,IRS2,NR4A3,ARRB1,AURKA,IFIH1,L1CAM |
| 3.845e-06 | -12.47 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | 191 | 40 | 17758 | 1761 |
CD99,SLC35D2,LGALS3,S100A11,IQGAP1,CD82,EPHA4,PTTG1,WEE1,OSBPL3,DUSP10,TAGLN2,TMEM64,FAR2,PDIA6,MYBL1,SNX10,MYO5A,ATP2B1,TNIP1,S100A4,SYNE2,DIAPH2,EZR,RNF19B,ALCAM,FAS,ARHGAP35,OPTN,ENDOD1,SLC6A6,AMMECR1,LRIG1,NOD2,RAB11FIP1,CTSA,PIEZO1,MAP3K5,AHR,GOLGB1 |
| 3.851e-06 | -12.47 | embryo development | biological process | GO:0009790 | 943 | 139 | 16441 | 1675 |
EMX1,ADD1,HSPG2,EPAS1,RET,CCNB1,PDGFB,CYP1A1,IMPAD1,ALDH1A3,ELF5,DLG1,ZBTB18,SPEF2,TFAP2C,ARFRP1,PRKRA,ICMT,ZFAND5,COL12A1,ABR,EDNRA,CXXC4,HS6ST1,PLCG1,HOXA9,TRAF3IP1,LRIG1,HDAC1,TANC2,GAB1,E2F8,MAFF,PCSK5,GRN,RUNX2,CDKN1C,SOX9,RAB23,NCKAP1,ELF3,MECOM,ITGA3,CYR61,GATA2,FLRT3,MEGF8,FRAS1,COL6A1,NEK2,WNT3A,MDFI,CYP26B1,EPB41L5,SALL4,VEZT,SCRIB,NPHP3,RASA1,CDK5R1,G2E3,GNAS,MMP15,NCOA3,ETS2,ITGA7,PLPP3,CCNB2,SEMA3A,RARG,EGLN1,HOXB7,NF2,GRHL2,ST14,THRA,TP53,BCL2L1,OSR2,STIL,PRKACA,RCN1,PDGFA,SETDB2,LMO4,DACT1,PLK4,TWIST1,ACSL4,ECE1,DVL2,SULF2,AKT1,DUSP4,ARHGAP35,SOCS3,SHROOM3,PTK7,NRG1,COBL,CTHRC1,NKX3-1,TNRC6C,LRP4,SDC4,TGFBR1,CRABP2,EFNB1,HOXB2,SIX4,PPP2R3A,FZD6,TOP2A,E2F7,BMP7,FUT8,BAX,TFAP2A,CITED2,SPRY2,PDGFC,HES1,TGIF1,UBE2A,PRICKLE1,COL7A1,TWSG1,ACVRL1,FGFR2,SPINT2,TBX18,NR4A3,ITGAV,ZMIZ1,SOX8,OSR1,FZD5,PLOD3,NCAPG2 |
| 3.863e-06 | -12.46 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 10597 | 1146 | 17570 | 1756 |
HECA,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,ZNF275,CDKN2C,MUC4,UBE2T,CRY2,TIPARP,MGAT5,TFAP2C,PRKAR2B,RNF19B,ARF4,PIAS3,ENPP1,PLCG1,MID1IP1,ATP7B,NOD2,HDAC1,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,COX6C,FAM21C,MARCH8,TFAP4,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,CADPS2,MYDGF,ZMYM1,NUP85,PPP6R1,MCCC2,REC8,PQLC3,PYM1,ERO1A,ELK1,PSMA4,GNA11,SFXN5,PLIN5,ETS2,S100A5,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,PTTG1,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,CDK19,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,DCAF7,ESRP1,SDC4,HABP4,CTSZ,SLC25A43,BEX2,SGPL1,CTNNBIP1,FUT2,MGAT4A,FAM20B,CST3,BAX,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,ACOT7,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,FANCI,CPNE2,RPS6KA2,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,STAU2,CBX6,NFE2L1,ARFRP1,SESN1,KDM4D,TRIM9,HS6ST1,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,RRAGD,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,ADCK5,RAB6A,HES2,B4GALNT1,RINL,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,USP43,HOXB7,CTDSPL,TP53,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,WDR44,BCL6,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,TAPBP,IDE,RBL1,STK38,IRF7,SYT13,ST3GAL1,ARFGEF3,BIN1,ZMAT1,CMAS,PINK1,CPEB4,CDCA8,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,RHOA,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,GGH,COL7A1,RNPEP,TXNDC11,SCG2,SH3BGRL2,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,HSPG2,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,OAT,SLC9A7,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SGCE,SPATA18,SLC35C1,KIF13A,LDB2,POR,PRIM1,PRDM5,BMP1,NFKBIZ,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,HERC6,PSIP1,MESDC2,C9orf69,DOPEY2,ZNRF2,BHLHE41,VASN,TPST1,PRKG1,SYTL3,GPR161,TRAK2,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,TJP3,FAM64A,FAAH,AGBL5,SFMBT1,KLK7,CABIN1,PER3,PLIN3,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,THRA,CCDC110,ATP2C2,FTH1,BCL2L1,CYP39A1,ZFYVE9,APOBEC3B,NOV,ACAP2,PDE4D,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,RAD17,PYGO1,PKMYT1,ITPR3,TRIQK,ATP10D,CEP162,DDOST,NGFRAP1,TRIOBP,SLC27A3,CBX7,DEPDC1,IGFBP6,CENPI,PBX3,FBXO6,EFNB1,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,GNB5,RNF128,FUT8,DRAM1,CD9,CITED2,PDGFC,TGIF1,ZWINT,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,DIAPH2,YES1,FOS,ARSK,CPTP,TIMP3,ACADSB,FGFR2,TBX18,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,ZFYVE16,RAB15,HSF2,METTL7A,SIVA1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,ZNF395,SERPINE2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,ELK3,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,TOB1,APOL2,COL16A1,RARG,SNX30,CCNE2,LMO7,SORBS1,FAM214B,HDAC11,PDIA5,COL18A1,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,REEP1,ECE1,SEPHS1,CHP1,C3orf52,CD40,FANCE,CASP4,ARHGAP35,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,ABCA1,GLIS3,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ARVCF,MYO5A,RBMS2,B3GALT6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,CTSL,SWAP70,RND3,TRIM69,CTSV,RAP2C,ARRB1,UACA,MCUR1,ZMIZ1,PLOD3,AHR,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,DHX8,SYTL4,MORF4L2,BARD1,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,CABP1,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,ICMT,CYP4F3,COL12A1,ANKRD6,DNM1L,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,NEK2,NCAM1,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,CYB5A,DCP2,DHX32,STK17A,NCOA3,SCARB2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,ARPC2,ZNF502,EGLN1,XDH,MTM1,CCDC109B,GRHL2,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,ZNF385B,CDS1,CCND1,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SSH3,FZD4,SYNE2,PLEKHO1,NUSAP1,CDCA2,RAB38,SLC9A6,RGS14,NKX3-1,PDIA3,PKN1,TMA16,NUCB2,GSTP1,ETS1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,ADD3,CTSC,ANKS1B,ARSG,ALG13,TMBIM6,ADAM15,ECI2,PLEKHF1,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,NEURL1B,CRISPLD2,PITX2,GALNT3,NR1D2,FHL1,HMGA1,CENPE,USF2,UNKL,CUL4B,EPHA4,NDC80,HDAC6,SDC1,NUP62CL,PDGFB,ELF5,DUSP10,MYBL1,TRAM1,S100A13,DDX59,ZNF462,PCGF5,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,MFAP3L,PLCH1,MSL1,WIPI1,MAP2,DOLPP1,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,ALDH3A2,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,SPATA13,TCF7,IFIT3,G2E3,EPN3,MAPKAPK2,COQ10A,H1F0,MFSD2A,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,UGP2,UPF3B,NF2,FOXM1,P3H2,XYLT1,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,N4BP3,LHX6,EGLN3,MINPP1,GM2A,DVL2,CTH,SIRT1,CPD,TMTC1,EVA1A,MBP,FIGNL1,COQ10B,S100A4,CDC20,DNAJC10,ATP1A1,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,CD63,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,ABCD1,BUB1,KLF9,TLE6,PSMB4,NR3C1,IFITM3,AMFR,PPARA,LITAF,FNDC3A,BCAR1,MAPK8IP1,PRDX4,FUCA1,SERPINA1,ZNF214,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,CENPN,NCS1,SESN3,CTGF,RGS3,ZFP36,STEAP2,PACSIN1,LAMP2,LOC81691,PBK,SNTB2,CASP9,GALNT7,PIF1,SAV1,MCFD2,CCNF,SLC25A5,AHRR,HLF,SLC25A4,RBM47,GNPTAB,FAM110C,SARAF,DHTKD1,MRPL44,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,SLC1A3,BMP2K,KIAA1161,MECOM,SNX18,BDH1,SORL1,PIKFYVE,FAM69A,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,AMER1,PIP4K2C,VEZT,GLT8D2,STX3,FAS,DGKH,PRKAG2,DCK,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,CAST,RPS6KA1,SNN,AIFM2,MNS1,APLP2,ZNF75D,CDKN1B,DAB2IP,LGMN,NR2C1,GPX4,MYO5B,SEC23A,LYRM1,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,NIN,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,HS3ST3B1,NR3C2,NUDT6,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,SIX4,TEAD3,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,SLC44A2,ATP8B1,CNOT6L,CNPY3,SPRY2,NCOA2,SHMT1,PARP4,FURIN,C1GALT1C1,GPLD1,NUCB1,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,DNER,SH3KBP1,TSEN34,ABCD4,CHPF,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,ANKRD12,RAB20,SUN3,RP2,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,MRPS36,PTGFRN,STK17B,NEIL1,ZNF114,RAP1GAP,STARD3NL,GRN,FAM213B,PIFO,PEX6,SAMD9,PHLPP1,ZNF432,RFX5,NCEH1,LRIF1,KDELR1,OXR1,GYLTL1B,HMG20B,GLCE,FECH,GNAS,ONECUT1,NUDT16,UTP14C,PLPP3,CDCA5,NFKBIA,ALPK3,KLF7,SLC25A24,SPC25,IL15,PSME2,MORC4,TDRKH,LRRC45,SS18,SLC25A48,SETDB2,ZDHHC12,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,ZNF525,OSTM1,ERBB2IP,DUSP4,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,ANXA3,SORT1,MIER3,AES,TRMT2B,POMGNT1,IRF2BPL,MDM1,ADORA1,GALNS,KIAA0319,SYPL1,SUN2,RAB3B,NR4A1,ASPM,OGDHL,MBNL3,HLA-B,C2orf70,HNRNPH2,PRCP,DHRS2,OTUB2,HOXB13,GEM,SOX8,SNPH |
| 3.865e-06 | -12.46 | Phosphatidylinositol signaling system | KEGG pathways | hsa04070 | 98 | 27 | 6908 | 758 |
MTM1,INPP5D,TMEM55B,PIK3R1,CALM1,DGKQ,PIP4K2C,CALM3,ITPR2,ITPR3,DGKE,CDS1,CALM2,DGKH,PLCG1,PTEN,IMPAD1,PLCG2,ITPR1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,PLCB2,DGKG |
| 3.865e-06 | -12.46 | Phosphatidylinositol signaling system | KEGG pathways | ko04070 | 98 | 27 | 6908 | 758 |
MTM1,INPP5D,TMEM55B,PIK3R1,CALM1,DGKQ,PIP4K2C,CALM3,ITPR2,ITPR3,DGKE,CDS1,CALM2,DGKH,PLCG1,PTEN,IMPAD1,PLCG2,ITPR1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,PLCB2,DGKG |
| 3.931e-06 | -12.45 | LE_EGR2_TARGETS_UP | MSigDB lists | LE_EGR2_TARGETS_UP | 107 | 27 | 17758 | 1761 |
PLK1,KIF20A,CDKN1C,FIGNL1,CDC20,PLEKHO1,CDCA8,KIF23,EZR,COL18A1,NUSAP1,CCNB1,ETS1,KIF11,CDK1,TOP2A,CCND1,UBE2T,RBL1,CORO1C,REEP1,PLK4,AURKA,BUB1,IQGAP3,CCNB2,CKS2 |
| 3.965e-06 | -12.44 | CROONQUIST_NRAS_SIGNALING_DN | MSigDB lists | CROONQUIST_NRAS_SIGNALING_DN | 72 | 21 | 17758 | 1761 |
PLK1,ZWINT,CENPA,SPC25,FOXM1,PTTG1,CDC20,NDC80,MYBL2,CCNB1,STIL,KIF11,CDK1,TOP2A,WEE1,PLOD2,PLK4,AURKA,HMGA1,UBE2C,CCNB2 |
| 3.968e-06 | -12.44 | BURTON_ADIPOGENESIS_3 | MSigDB lists | BURTON_ADIPOGENESIS_3 | 101 | 26 | 17758 | 1761 |
CCNE2,PLK1,MTM1,KIF20A,DLGAP5,NQO1,FIGNL1,CDC20,CDCA8,NUSAP1,IL13RA1,CCNF,CCNB1,KIF11,CDK1,PRIM1,TOP2A,DCK,LMO4,CSTF2,AURKA,KLF5,BUB1,CCNB2,ABCA1,CKS2 |
| 3.999e-06 | -12.43 | TYRKINASE | prints domains | PR00109 | 98 | 25 | 4759 | 462 |
LMTK3,TESK1,EPHA4,RET,ERBB2,TESK2,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,EPHA10,JAK1,IGF1R,FGFR2,LIMK1,AXL,PTK7,RYK,MAP3K9,ERBB3,EPHB4,JAK3,SYK |
| 4.030e-06 | -12.42 | plasma membrane | cellular component | GO:0005886 | 4806 | 561 | 17570 | 1756 |
ADD1,SLC25A13,RET,CACNA2D2,NRG2,LYNX1,TGOLN2,SYTL4,MORF4L2,GRM5,CALM2,MUC4,CABP1,FUT1,CLDN4,PIK3CD,TIAM1,PRKAR2B,F12,ARF4,ABR,PLCG1,ENPP1,ATP7B,NOD2,RELL1,ARF6,HSPB1,SCN5A,ITGA6,RAB23,FAM21C,MERTK,TTYH3,FLRT3,PCYOX1,PANX2,NCAM1,DGKG,ULBP2,MYLIP,PAQR7,GNA11,PTPRF,ETS2,SLC4A4,SEMA4D,RAET1L,STK39,MAL2,DRP2,ARPC2,RUSC1,TMEM173,MTM1,GRHL2,CD82,RGS20,PKP2,IL13RA1,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,MUC16,SCNN1A,CDH1,ENPP5,RTKN2,ARL4D,LRP11,DLG3,RAB27B,SCN3A,ENPP4,COL6A2,FZD4,PLEKHO1,SYNE2,CYS1,RAB38,XRCC6BP1,GABARAPL1,IRS2,ALDH3B1,SHROOM3,SLC9A6,CORO1C,AXL,SIPA1L1,TRABD2A,PRIMA1,RGS14,TTC8,TCAF1,SDC4,BTN3A1,CTSZ,ANO9,NUCB2,PKN1,PLPPR4,SRPX2,NEO1,DIRAS3,CXCL16,ADD3,IGSF9,ITGB8,SLC27A6,ANKS1B,CALD1,ADAM15,TMBIM6,WWP1,IGFBP2,SGCB,TPCN1,S100A6,AMOTL2,PVRL4,PLSCR1,FMN1,RAPGEF2,PIK3R1,GRIN1,SNTB1,CNTNAP1,ACVRL1,RAB11FIP2,SYT7,ITGAV,FHL1,CYBRD1,BCAM,ILDR1,EPHA4,F11R,ITPR2,HDAC6,PDGFB,SDC1,SPTB,SUSD2,CPNE2,NPNT,SHC3,IL6ST,SLC44A1,ABCA2,NTN4,ANO4,TLN2,SMAGP,CD55,KCNIP3,CELSR2,CR2,EZR,MFAP3L,HS6ST1,PLCH1,KCNMB4,PRKCDBP,ARRDC1,PIK3C2B,PIEZO1,PRSS8,BMF,LGALS3,RASA2,FXYD3,HLA-F,SLC22A31,NCKAP1,CNTNAP2,DHRS3,ANO1,IL18R1,B4GALNT1,IGF1R,FRAS1,TBCD,EXOC8,SELK,PIM1,WNT3A,MPHOSPH9,CKAP4,ABCC1,PCDH1,RGMB,SPATA13,SCRIB,PRX,CDK5R1,RASGRP2,EPN3,COL13A1,PVRL2,MFSD2A,PHLPP2,CSF1,ITGA7,SLC2A6,PLD1,ATP1B3,IFI6,NIPA1,NF2,ERBB2,SLC7A2,EMP2,BCAP31,SYTL2,EFR3A,PLCG2,SRR,CDH3,OAS3,NOTCH3,SCN2A,GM2A,DVL2,SULF2,CLCN3,MBP,EVA1A,AKT1,PTGER4,DAG1,ATP13A2,DUOX1,ATP1A1,IDE,PTPRJ,ABHD12,PTK7,MMP17,EFNA5,SYT13,BIN1,PACSIN2,CDH22,CD63,ADGRG1,BLVRB,SELL,GABRG2,AIP,FZD6,PARM1,SLC9A2,SIRPA,NRP2,M6PR,ZDHHC21,CD109,CDK16,ALPP,SGK1,TSPAN13,KLF9,SYK,ATP2B1,IGDCC4,HMMR,DLGAP1,RHOA,IFITM3,CRB3,PLAUR,LITAF,BCAR1,RNPEP,BBS2,DGKE,CD83,FAT4,NETO2,ICOSLG,ZBTB33,ARHGEF4,DIS3L,LAMP1,HSPG2,SSH1,LGR4,VANGL1,ATP8A1,PLXNA1,PJA2,SLC20A1,NCS1,CTGF,STIM1,RGS3,OSBPL3,IL31RA,PIK3CA,KCNS3,STEAP2,TACSTD2,HYLS1,PACSIN1,METAP2,XKR8,LAMP2,SGCE,ACVR1C,SNTB2,SLC25A5,SLC25A4,NKD1,UNC5B,F2RL1,TRAF5,LZTS1,DDX58,SEMA6B,HLA-E,DGKQ,SLC1A3,TSPAN7,MESDC2,ITGA3,RALGPS2,PIK3AP1,ZNRF2,LYPD3,SNX18,VASN,SLC16A6,PRKG1,OPN3,DAPK1,SORL1,CD70,TNFRSF12A,CACNA1D,SYTL3,GPR161,RIMS2,TRAK2,EPB41L5,FADS2,KCNJ12,MFI2,MMD,MICB,ANO6,AMER1,CALM1,VEZT,EPHA1,ATP8B3,ANTXR1,STX3,RASA1,FAS,DGKH,MMP15,SLCO4A1,GABRD,PLEKHH2,TJP3,SLC4A3,PCDH19,EHD1,SPRED1,SLC2A4,TCTN2,TRIP10,ST14,IQGAP1,ATP2C2,KCTD12,CD274,DDR1,EPS8L2,APLP2,CNNM4,DAB2IP,EPHB4,PDE4D,PHKA2,TSPAN1,UTRN,PRKCQ,SLC11A2,ATP1B1,ITPR3,ALCAM,ATP10D,FZD7,EPHA10,JAK1,STK26,TSPAN18,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,COBL,ATP9A,EPS8,ARL4C,EFNB1,ADGRB2,HLA-A,SNTA1,GNB5,PTEN,CD9,SLC44A2,ATP8B1,ERBB3,SPRY2,SLC16A5,RASGRF1,PDGFC,ARHGEF28,ERMAP,MPP1,FURIN,YES1,AIF1L,CPTP,FGFR2,RYK,ABCB1,GRIN2D,GPER1,FZD5,OCLN,MELK,DEF6,ESYT2,RGMA,CASP3,MPP5,SLC8B1,DNER,CACNB4,TMC1,SH3KBP1,ABCD4,HTR1D,EPCAM,NKAIN3,RAB15,TSPAN6,DLG1,TRPC1,RAB20,RP2,CTTN,SLC39A10,MYRIP,PTPRE,RASGRP1,ITCH,ROR1,STK17B,EDNRA,GPRC5B,KCNK1,MADD,ADIPOR1,CAPN1,CPPED1,CD99,ARAP3,SERPINE2,BVES,ABCG2,CALM3,TEC,PHLPP1,CA2,KCNN4,COL6A1,FXYD5,C10orf54,HLA-C,SLC12A2,GAD1,CCDC88A,PODXL2,BTN3A2,NUBP1,STEAP1,XKRX,GNAS,SLC6A6,UAP1,TMEM30A,PLPP3,NFKBIA,CDCA5,RHOBTB2,JAK3,SHROOM2,PROM2,SORBS1,IL15,HDAC11,MRAS,IL27RA,LRRC45,KIF14,ECE1,F2R,PDIA6,SEPHS1,CHP1,FRS3,SUSD3,GCA,PTPRU,SLC39A8,IGSF8,ERBB2IP,CD40,JADE1,BFSP1,SECTM1,SPTBN5,ABCA1,LIFR,ANXA3,SORT1,ENO2,TSPAN15,FRMD6,LRP4,TGFBR1,IL17RB,ADRBK1,ADORA1,LLGL2,KIAA0319,ARVCF,IQGAP3,SYPL1,RAB3B,LEPR,HLA-B,SWAP70,TRIM69,PRCP,RAP2C,CTSV,ARRB1,GEM,L1CAM,ABCG1,CD33 |
| 4.078e-06 | -12.41 | cell junction | cellular component | GO:0030054 | 1147 | 161 | 17570 | 1756 |
ILDR1,KIAA1462,ADD1,HSPG2,EPHA4,F11R,MPP5,PJA2,SDC1,NCS1,SH3KBP1,EPCAM,CABP1,DLG1,AKR1B1,CLDN4,IRF2,POF1B,CTTN,TLN2,PACSIN1,TIAM1,SMAGP,SNTB2,EZR,TNS1,TRIM9,PLCG1,DNM1L,KCNK1,LIMK1,ARF6,HSPB1,LZTS1,CAPN1,DDX58,CD99,LASP1,SCN5A,MRC2,FRMD4A,BVES,ITGA6,CALB2,KIF23,TEC,NCKAP1,TNS3,ITGA3,ZNRF2,RIMS3,FLRT3,TBCD,CADPS2,PANX2,PIKFYVE,RIMS2,EPB41L5,DDB2,PCDH1,SCRIB,VEZT,STEAP1,DCP2,STX3,RASGRP2,SCARB2,GABRD,TJP3,PVRL2,COL13A1,PLPP3,ITGA7,ARPC2,SHROOM2,AFAP1,RUSC1,LMO7,SORBS1,NF2,GRHL2,IQGAP1,PKP2,KCTD12,BCL2L1,CCND1,NOV,CDH1,DACT1,CDH3,DIXDC1,EPB41L4B,DLG3,SCN2A,CHP1,CAMSAP3,AKT1,FZD4,PTPRU,SYNE2,UTRN,ATP1B1,ERBB2IP,GTF2A2,ALCAM,DAG1,ATP1A1,PTPRJ,JAK1,SHROOM3,PTK7,CORO1C,SIPA1L1,TRIOBP,PRIMA1,RGS14,FBLIM1,PACSIN2,FRMD6,EPS8,SDC4,PDIA3,GABRG2,TGFBR1,SRPX2,SNTA1,ADD3,IGSF9,CDK16,ANKS1B,CD9,ADAM15,IQGAP3,PVRL4,DLGAP1,AMOTL2,RHOA,FMN1,CRB3,RAPGEF2,PLAUR,PIK3R1,GRIN1,YES1,AIF1L,SNTB1,BCAR1,ARHGAP24,RPL12,RND3,SYT7,RAP2C,GRIN2D,ITGAV,FHL1,HMGA1,GPER1,FZD5,L1CAM,OCLN,SNPH |
| 4.091e-06 | -12.41 | MARKEY_RB1_ACUTE_LOF_DN | MSigDB lists | MARKEY_RB1_ACUTE_LOF_DN | 219 | 44 | 17758 | 1761 |
LMO7,GCLM,DLGAP5,SCOC,NQO1,CKAP2,PDIA3,KIF23,CCNB1,FBLN1,PSIP1,IGF1R,UBE2T,RANBP1,NEK2,AHCY,BUB1,IQGAP3,SLC12A2,TIPARP,CKS2,PLK1,CENPA,KIF20A,FIGNL1,GCLC,CBX6,PTGER4,NUSAP1,ANLN,CCNF,KIF11,H2AFV,CDK1,FAS,PRIM1,FAM64A,TIMM8A,RBL1,CDCA7L,CDCA5,AURKA,CCNB2,E2F8 |
| 4.202e-06 | -12.38 | LUCAS_HNF4A_TARGETS_UP | MSigDB lists | LUCAS_HNF4A_TARGETS_UP | 56 | 18 | 17758 | 1761 |
MTM1,LASP1,MPP1,SDC4,PKP2,IL13RA1,MGST2,SEPP1,IL18R1,ALDH5A1,ATP7B,KIF13B,OSBPL3,ABCB1,ERBB3,TECR,COBL,SMAGP |
| 4.202e-06 | -12.38 | NAGASHIMA_EGF_SIGNALING_UP | MSigDB lists | NAGASHIMA_EGF_SIGNALING_UP | 56 | 18 | 17758 | 1761 |
HES1,NR4A1,PHLDA1,FOS,IER3,ETS2,CTGF,CYR61,KBTBD2,ZFP36,FOSB,NR4A3,TNFRSF12A,NR4A2,GEM,F2RL1,TIPARP,MAFF |
| 4.239e-06 | -12.37 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 126 | 30 | 17758 | 1761 |
PGM1,ENO2,ZNF395,NR3C1,PLAUR,S100A4,SAT1,SOX9,AK4,GDF15,LOXL2,FOS,S100A2,PHLDA1,CYB5A,ELF3,SLCO4A1,ARTN,P4HA2,ITPR1,OPN3,LIMCH1,PIM1,CITED2,EGLN3,MAFF,S100A6,KLF7,RRAGD,EGLN1 |
| 4.399e-06 | -12.33 | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | 192 | 40 | 17758 | 1761 |
CDK17,NFKBIE,SDC4,OSGIN2,GDF15,PHLDA1,TNFSF9,IER3,RPS6KA2,SETDB2,ZFP36,BCL6,SGK1,RAB20,PIM1,CITED2,TIPARP,CKS2,TGIF1,PLSCR1,USP18,BCL9,PTGER4,DUSP4,ANLN,ZFAND5,RNF19B,FOS,SOCS3,RND3,PLK2,PHLPP2,NFKBIA,SLC2A6,FAM83D,NFKBIZ,ST3GAL1,TOB1,MAFF,EHD1 |
| 4.399e-06 | -12.33 | GSE3982_CTRL_VS_LPS_48H_DC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_DN | 192 | 40 | 17758 | 1761 |
PARP12,LRRFIP2,NQO1,PSME2,HERC5,LGALS3BP,DRAM1,TWIST1,RFX5,IFIT1,PIM1,CTTN,APOBEC3G,FAM69A,ABCC1,LAMP3,MX1,PPIF,ALDH2,PODXL2,TNIP1,IFITM3,PLAUR,COQ10B,PRKAR2B,RUNX3,IFIT3,RNF19B,FANCE,SPTLC2,CYB5A,CRISPLD2,JAK1,SERPINA1,RND3,CSF1,NFKBIA,IRF7,ARSB,IFI6 |
| 4.399e-06 | -12.33 | GSE3982_DC_VS_NKCELL_UP | MSigDB lists | GSE3982_DC_VS_NKCELL_UP | 192 | 40 | 17758 | 1761 |
LAMP1,NFKBIE,LGALS3,NQO1,RAB23,NDRG2,IL13RA1,MRAS,FTH1,CTSZ,NANS,PPP2R3A,ARHGEF10L,MITF,DRAM1,CD9,SGK1,RAB20,TACSTD2,CTTN,GM2A,CCDC88A,PDGFC,TNIP1,AK4,DIAPH2,TNS1,ASB13,CD83,RBM47,NGFRAP1,H1F0,P4HA2,CSF1,PPM1H,NR4A3,DTX4,MDH1,CENPE,CPPED1 |
| 4.399e-06 | -12.33 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | 192 | 40 | 17758 | 1761 |
CMAS,TXN,DLGAP5,LGALS3,GNPDA1,CRYM,DAP,NDUFA4,ISYNA1,NANS,DPP8,COX6C,MNS1,AIP,REPS1,LGALS3BP,TOP2A,CDKN2C,TAGLN2,IQGAP3,SGCB,PQLC3,USP18,CDC20,HTATIP2,GGH,ARHGDIB,NUSAP1,KIF11,CDK1,SLC25A4,DDOST,CORO1C,NAT1,CDCA5,DBI,CCNB2,E2F8,ACOT7,XDH |
| 4.430e-06 | -12.33 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 313 | 57 | 17758 | 1761 |
CASP3,RUNX2,FRMD6,RASA2,TGFBR1,TRIB2,SCML1,SGPL1,AKIRIN1,RASSF8,PDGFA,WEE1,B3GALNT1,CTGF,IMPAD1,SLC44A1,RUNDC3B,TPST1,ECI2,LIMCH1,TECR,ZMYM1,F2R,SEPHS1,SOCS5,ENPP4,DOCK4,PDGFC,NR3C1,SLC39A8,OXR1,MRS2,FBXO9,KIF13A,GALNT7,ALCAM,PDIK1L,STK17B,LEPR,RANBP9,CYB5A,DCP2,GLCE,STK17A,AHRR,ENPP1,POPDC3,MAP2,RAP2C,HDAC1,EFNA5,HS3ST3B1,F2RL1,TMEM14A,ISOC1,DEF6,DOCK9 |
| 4.491e-06 | -12.31 | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | MSigDB lists | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | 46 | 16 | 17758 | 1761 |
EXPH5,TXN,DLGAP5,ASPM,NUSAP1,MORF4L2,OAT,DENND2D,TOP2A,DLG1,CDKN1B,CENPE,TAGLN2,TIAM1,UBE2C,APOBEC3G |
| 4.494e-06 | -12.31 | HALLMARK_INTERFERON_GAMMA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_GAMMA_RESPONSE | 199 | 41 | 17758 | 1761 |
DDX58,PLA2G4A,CASP3,PARP12,IL15RA,IL15,PSME2,TAP1,PSME1,CD274,HERC6,LGALS3BP,HLA-A,TRIM21,IRF2,IFIT1,OAS3,PIM1,MX1,RIPK2,PLSCR1,IFITM3,STAT4,USP18,CD40,IFIT3,CASP4,SOCS3,FAS,HLA-B,NCOA3,TAPBP,BANK1,SECTM1,NFKBIA,NMI,NLRC5,IRF7,CMPK2,IFIH1,ISOC1 |
| 4.497e-06 | -12.31 | cellular localization | biological process | GO:0051641 | 2209 | 286 | 16441 | 1675 |
SUN1,LAMP1,ACACB,GAA,SLC25A13,TAP1,TGOLN2,SYTL4,CCNB1,CALM2,AP1M2,CTGF,STEAP2,SNX16,TINAGL1,PIK3CD,PACSIN1,LAMP2,KIF13A,ICMT,MCFD2,RNF19B,ARF4,DNM1L,GNPTAB,ATP7B,TRAF3IP1,NOD2,ARF6,F2RL1,NFKBIE,GGA1,SOX9,RAB23,GPSM2,SLC1A3,FAM21C,MERTK,LMNA,ATG4A,MESDC2,DOPEY2,SNX18,ATP5H,RIMS3,RPL39,RANBP1,SORL1,CADPS2,PIKFYVE,SYTL3,NUP85,PPP6R1,RIMS2,TRAK2,PMPCB,CALM1,ERO1A,NPC2,PLIN5,STX3,AP1AR,SCARB2,PRKAG2,TIMM8A,ITPR1,FAM83D,AURKA,NDE1,HOOK1,NRBP1,NUP58,EHD1,MTM1,CCDC109B,ARMCX3,DLGAP5,THRA,PKP2,FTH1,BCL2L1,ZFYVE9,APPBP2,ACAP2,CDH1,IFIT1,ARL4D,RAB27B,DLG3,SNX10,ATG4D,MYO5B,SEC23A,SEC61B,COG2,FZD4,SYNE2,HTATIP2,KIF1C,NUSAP1,ATP1B1,PYGO1,RAB38,ITPR3,ATP10D,NIN,DDOST,AXL,PRIMA1,RGS14,SLC25A30,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,SIX4,PDIA4,RNF128,CTSC,BAX,KLC3,CD9,PLEKHF1,SPRY2,ZWINT,LCA5,TACC1,ZC3H11A,RAPGEF2,PIK3R1,MRS2,FURIN,CNTNAP1,RPL12,FGFR2,RAB11FIP2,SYT7,NR4A3,CENPE,ARSB,WDR45B,ESPL1,EXPH5,UGT8,CPT2,NDC80,ARFGEF1,MPP5,F11R,HDAC6,ERP29,SLC8B1,PDGFB,ZFYVE16,RAB15,DPYSL2,DLG1,RAB20,SUN3,RP2,CTTN,TLN2,MYRIP,TRAM1,S100A13,RASGRP1,PLK1,KCNIP3,CENPA,EZR,ARFRP1,CDK1,OPTN,TRIM9,WIPI1,RAB11FIP1,PCSK5,RRAGD,GRN,PRKAA2,PEX6,ETV5,CALM3,CNTNAP2,RAB6A,GATA2,KIF13B,EXOC8,WNT3A,GAD1,KDELR1,MDFI,STRADB,BTN3A2,SCRIB,NUBP1,GNAS,PVRL2,TMEM30A,CDCA5,NFKBIA,SH3BP4,ZDHHC7,CTSA,LTBP2,PLD1,ATP1B3,SHROOM2,JAK3,TOB1,SLC25A24,UPF3B,TP53,STIL,EMP2,BCAP31,SYTL2,TTC21B,PDGFA,SVBP,KIF14,ZDHHC12,REEP1,PLCG2,ZDHHC23,BCL6,RPN2,LMAN1,F2R,DVL2,CHP1,PPIF,AKT1,PTPRU,DAG1,TAPBP,ALDH5A1,PEX2,SPTBN5,SYT13,ABCA1,ANXA3,PACSIN2,SORT1,PINK1,TSPAN15,CD63,FRMD6,LRP4,CDCA8,PSMD10,AIP,VPS26A,HMGXB4,M6PR,ZDHHC21,KIF5B,MLPH,ADORA1,CDK16,LLGL2,BMP7,ABCD1,SYK,MYO5A,HES1,SUN2,RAB3B,FBLN5,CRB3,ASPM,PRICKLE1,COL7A1,BBS2,SCRN2,SERPINA1,SCG2,ARRB1,MCUR1,SPCS3,GEM,NDFIP1,ABCG1,SNPH |
| 4.529e-06 | -12.31 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 913 | 135 | 16441 | 1675 |
SSH1,LGR4,EPHA4,HEXB,RET,PLXNA1,VASH1,SH3KBP1,DPYSL2,DLG1,TACSTD2,NTN4,MYH14,SEMA3G,CTTN,TIAM1,S100A13,CYP1B1,STRIP2,EZR,POR,ABR,PLCG1,DNM1L,LIMK1,NKD1,SP6,ITPKA,HSPB1,MYL12B,LZTS1,FGD1,SEMA6B,RUNX2,ARAP3,TBC1D1,BVES,SOX9,ETV5,FAM21C,FBLN1,GATA2,MEGF8,VASN,KIF13B,TNFRSF12A,MYDGF,WNT3A,ZRANB1,RIMS2,EPB41L5,MFI2,EPHA1,NPHP3,NFIB,CDK5R1,RASA1,AP1AR,SEMA4D,ITGA7,CSNK1G1,CSF1,FGD6,ARPC2,SEMA3A,XDH,ADAMTS16,EGLN1,EHD1,HOXB7,ERBB2,OSR2,EMP2,MNS1,PDGFA,SP100,BCL6,VAT1,TWIST1,DAB2IP,ETV4,DVL2,SEMA3B,SSH3,HTATIP2,DAG1,FZD7,ARHGAP35,SHROOM3,BHLHB9,PTK7,CORO1C,SIPA1L1,TRIOBP,NRG1,EFNA5,WASF3,CTHRC1,FBLIM1,ANXA3,PINK1,CIT,LRP4,EPS8,GDF15,TGFBR1,CRABP2,PKN1,ETS1,SRPX2,FZD6,PPP2R3A,SIX4,ADGRB2,HDAC9,PTEN,BMP7,CST3,TFAP2A,BAX,CITED2,TRIM62,TGIF1,HES1,RHOA,RAPGEF2,GRIN1,RGCC,ACVRL1,FGFR2,TBX18,ERAP1,OSR1,SOX8,L1CAM |
| 4.621e-06 | -12.28 | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | 114 | 28 | 17758 | 1761 |
NFE2L3,FBLIM1,PDGFC,SLC25A24,PRSS23,FXYD3,EZR,PKP2,TFAP2C,TCF7,GALNT7,ATP1B1,IDH1,PSIP1,EDNRA,SOX13,WEE1,PRKAG2,MLPH,TJP3,GRHL1,RND3,KCNK1,SLC44A2,ERBB3,FHL1,OCLN,PROM2 |
| 4.650e-06 | -12.28 | EF_hand_dom | interpro domains | IPR002048 | 220 | 44 | 18293 | 1814 |
MYL9,SLC25A24,REPS2,S100A11,SLC25A13,CALB2,CALM3,EFHD2,NUCB2,S100A2,REPS1,HPCAL4,PPP2R3A,NCS1,PLS3,RCN1,CALM2,CABP1,DGKG,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,MCFD2,AIF1L,MYL12A,RASGRP2,NIN,DUOX1,PLCG1,NUCB1,PLCH1,SWAP70,GNPTAB,CGREF1,NKD1,S100A5,EFCAB14,CAPN1,EHD1 |
| 4.704e-06 | -12.27 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 481 | 79 | 17758 | 1761 |
LZTFL1,SLC35D2,BCAM,PAPSS2,HDAC11,FHDC1,KCTD12,TEX2,SNN,FAM46C,SLC44A1,EPB41L4B,TMEM64,RCAN3,SCARA3,NEB,SMARCA2,SNTB2,SH3BGRL,SYNE2,TNS1,KCTD2,SESN1,TMEM164,ENPP1,SLC25A4,ANKRD6,WFS1,LRIG1,GLCCI1,ST3GAL1,LIFR,CBX7,RRAGD,ZMAT1,GLIS3,WASF3,PINK1,TBC1D1,ZCCHC24,SLC25A27,ASAH1,GSTP1,ARHGEF40,PARM1,NEO1,CCDC92,MLPH,FRY,FLRT3,RRBP1,PRKG1,SORL1,SGK1,KLF9,MYLIP,ALDH3A2,HES1,PHF20L1,FOS,GLT8D2,FRMD4B,GNAS,FECH,ARHGAP24,CACHD1,TIMP3,BANK1,SLC4A4,MATN2,ITPR1,NR4A2,SH3BGRL2,FHL1,ZMIZ1,NDFIP1,TOB1,PKIA,CYBRD1 |
| 4.748e-06 | -12.26 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | MSigDB lists | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | 179 | 38 | 17758 | 1761 |
PARP12,ENO2,REPS2,DNAJB2,HABP4,C6orf106,PKP2,F11R,CYP26A1,APOBEC3B,ALPP,CD9,PIK3CD,CDKN2D,TIMP2,ITCH,RAPGEF2,C3orf52,SPTLC2,STX3,ARF4,RASGRP2,OPTN,FUCA1,PGF,KLF12,CGREF1,ITPR1,CLMN,SERPINI1,IRF7,GDF11,FHL1,PLIN3,NRGN,LIFR,EHD1,NXT2 |
| 4.879e-06 | -12.23 | APPEL_IMATINIB_RESPONSE | MSigDB lists | APPEL_IMATINIB_RESPONSE | 32 | 13 | 17758 | 1761 |
GNS,LAMP1,LAMP2,FUCA1,PLSCR1,GUSB,OSBPL3,HEXB,ASAH1,CTSZ,CTSA,PLD1,GM2A |
| 4.879e-06 | -12.23 | FARMER_BREAST_CANCER_CLUSTER_2 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_2 | 32 | 13 | 17758 | 1761 |
CENPA,KIF20A,ASPM,ESRP1,PTTG1,NDC80,NEK2,BUB1,NUSAP1,CENPE,CCNB2,KIF11,MELK |
| 4.890e-06 | -12.23 | Fc receptor signaling pathway | biological process | GO:0038093 | 357 | 64 | 16441 | 1675 |
SPRED1,PSME2,NRG2,ERBB2,PSME1,ITPR2,PDGFB,SPTB,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKCQ,AGO4,ITPR3,IRS2,PLCG1,JAK1,LIMK1,NRG1,SPTBN5,GAB1,TNRC6C,RASA2,PSMD10,CALM3,NCKAP1,TEC,PHLPP1,FGF19,PTEN,ERBB3,NCAM1,SYK,RASGRF1,PSMB4,RAPGEF2,NR4A1,PIK3R1,CALM1,GRIN1,YES1,FOS,PSMA4,RASA1,FGFR2,PHLPP2,ITPR1,NFKBIA,NR4A3,GRIN2D,ARPC2,JAK3 |
| 4.903e-06 | -12.23 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | 186 | 39 | 17758 | 1761 |
SLC25A24,CDKN1C,ARHGEF11,FRMD6,ZCCHC24,ERI2,TDRKH,VARS2,GPSM2,SNN,COX6C,TMCC3,RCN1,FRY,PPP4R1,MDFIC,TMEM64,ZRANB1,TIAM1,NEB,S100A13,RASGRP1,GM2A,ATP2B1,REC8,CENPA,IFITM3,BCL9,UBE2A,PRICKLE1,VWA1,NUSAP1,DNAJB14,ZFAND5,NFIX,ETS2,WFS1,SH3BGRL2,CENPE |
| 4.942e-06 | -12.22 | lytic vacuole | cellular component | GO:0000323 | 517 | 84 | 17570 | 1756 |
LAMP1,GAA,HSPG2,TRIP10,HEXB,SDC1,EPDR1,ABCD4,PQLC2,AP1M2,ABCA2,AKR1B1,SNX16,GOT1,ECE1,TINAGL1,PIK3CD,MARCH2,TSPAN1,LGMN,NAGA,S100A13,TMEM9,GM2A,RASGRP1,LAMP3,LAMP2,EVA1A,OSTM1,SLC11A2,RNF19B,RHEB,ATP13A2,ENPP1,HPSE,GLA,CAPN1,RRAGD,STARD3NL,SORT1,CD63,TMEM55B,SDC4,ASAH1,CTSZ,M6PR,TMEM63A,MARCH8,GNS,CTSC,ARSG,ZNRF2,GATA2,VASN,CST3,GALNS,COL6A1,PCYOX1,DRAM1,PLEKHF1,SLC44A2,C9orf72,TPCN1,MYO5A,MMD,IFITM3,GUSB,LITAF,GGH,NPC2,GNA11,STX3,GPLD1,CTSL,FUCA1,SCARB2,SYT7,PRCP,CTSV,NR4A3,ARRB1,CTSA,PLD1,ARSB |
| 4.942e-06 | -12.22 | lysosome | cellular component | GO:0005764 | 517 | 84 | 17570 | 1756 |
LAMP1,GAA,HSPG2,TRIP10,HEXB,SDC1,EPDR1,ABCD4,PQLC2,AP1M2,ABCA2,AKR1B1,SNX16,GOT1,ECE1,PIK3CD,TINAGL1,MARCH2,TSPAN1,LGMN,NAGA,S100A13,TMEM9,GM2A,RASGRP1,LAMP3,LAMP2,EVA1A,OSTM1,SLC11A2,RNF19B,RHEB,ATP13A2,ENPP1,HPSE,GLA,CAPN1,RRAGD,STARD3NL,SORT1,CD63,TMEM55B,SDC4,ASAH1,CTSZ,M6PR,TMEM63A,MARCH8,GNS,CTSC,ARSG,ZNRF2,GATA2,VASN,CST3,GALNS,COL6A1,PCYOX1,DRAM1,PLEKHF1,SLC44A2,C9orf72,TPCN1,MYO5A,MMD,IFITM3,GUSB,LITAF,GGH,NPC2,GNA11,STX3,GPLD1,CTSL,FUCA1,SCARB2,SYT7,PRCP,CTSV,NR4A3,ARRB1,CTSA,PLD1,ARSB |
| 5.011e-06 | -12.20 | MAPK cascade | biological process | GO:0000165 | 372 | 66 | 16441 | 1675 |
SPRED1,RPS6KA1,PSME2,RET,ERBB2,NRG2,IL18,PSME1,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,DOK4,IL31RA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,MAP3K3,RIPK2,PTGER4,DUSP4,MAP3K6,IRS2,JAK1,NOD2,NRG1,SPTBN5,GAB1,MAPK12,RASA2,SOX9,PSMD10,CALM3,PKN1,TNFRSF19,FGF19,MAP3K9,MDFIC,MAPK11,ERBB3,IQGAP3,NCAM1,SYK,MDFI,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,ELK1,FOS,PSMA4,RASA1,MAPK8IP1,MAPKAPK2,SCG2,FGFR2,GRIN2D,ITGAV,MAP3K5,JAK3 |
| 5.027e-06 | -12.20 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | 193 | 40 | 17758 | 1761 |
CCDC109B,ATP8A1,ITPR2,GPSM2,ETS1,CARD10,TMPRSS4,SH3KBP1,EPCAM,RALGPS2,CDH1,PHTF1,DAPK1,TPST1,KLC3,UBE2J1,DUSP10,MBP,RHOA,PQLC3,MPP1,MBNL3,SLC11A2,ATP1B1,C3orf58,CYB5A,DGKE,SOCS3,LRRC42,PTPRF,COQ10A,ETS2,AXL,SPINT2,NR4A3,AGFG2,EPB41L4A,PLIN3,GLCCI1,TMEM131 |
| 5.027e-06 | -12.20 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | 193 | 40 | 17758 | 1761 |
DLGAP5,LGALS3,S100A11,GNPDA1,DAP,PTTG1,MNS1,IL18R1,AIP,REPS1,HLA-A,DAPK2,CDKN2C,MDFIC,TMEM37,SNX10,S100A13,S100A6,PQLC3,PLSCR1,SNTB2,S100A4,LITAF,ARHGDIB,DOCK5,RNF19B,CASP4,CDK1,PRDX4,GABARAPL1,GALNT3,CARHSP1,JAK1,DBI,CTSA,GEM,ARF6,E2F8,ACOT7,XDH |
| 5.086e-06 | -12.19 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-HSA-4420097 | 312 | 59 | 8202 | 867 |
WASF3,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,NCKAP1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ELMO2,SHC3,PIK3CA,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,RHOA,PSMB4,AKT1,RAPGEF2,CALM1,PIK3R1,GRIN1,DUSP4,ITPR3,BCAR1,PSMA4,RASA1,MAPKAPK2,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,AXL,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,ITGAV,JAK3,HSPB1,MAPK12 |
| 5.134e-06 | -12.18 | negative regulation of cell proliferation | biological process | GO:0008285 | 633 | 100 | 16441 | 1675 |
CASP3,NF2,S100A11,IL15,INPP5D,CNOT8,P3H2,TP53,FBXO2,COL18A1,PKP2,ERBB2,NDRG2,FTH1,TP53I11,CD274,VASH1,CDKN2C,NOV,BTG3,RPS6KA2,FABP6,BCL6,DLG1,CDKN1B,DAB2IP,DLG3,CDKN2D,F2R,ETV4,CYP1B1,SMARCA2,TIMP2,ING1,ACVR1C,PTPRU,ITCH,PRKRA,SAV1,SESN1,PTPRJ,PEX2,OVOL1,KLF11,NKX3-1,CDKN1C,IGFBP6,SERPINE2,ADGRG1,SOX9,TGFBR1,PKN1,ETS1,GSTP1,FBLN1,CD109,CTNNBIP1,TFAP4,E2F7,ADORA1,PTEN,GATA2,BMP7,TFAP2A,CD9,BAX,MAPK11,KLF9,C10orf54,SPRY2,TGIF1,HES1,RAPGEF2,RGCC,PDE5A,RUNX3,EIF2AK1,IFIT3,NFIB,GPLD1,PRDX4,FGFR2,SCG2,ACVRL1,DHRS2,CGREF1,CTSV,SH3BP4,CLMN,GPER1,GDF11,HMGA1,FZD5,NDFIP1,TOB1,PTGES,RARG,CD33,JARID2,XDH |
| 5.147e-06 | -12.18 | V$CEBP_Q3 | MSigDB lists | V$CEBP_Q3 | 242 | 47 | 17758 | 1761 |
PLA2G4A,NCKAP5,SPRED1,LRRFIP2,DDIT4L,THRA,ETV5,ERBB2,HMGN3,PDGFB,TSPAN7,SIRPA,FOXP2,SS18,PTEN,CYR61,ANKS1B,CDK16,CALD1,LMO4,RRBP1,BCL6,NCAM1,PLCB2,MAP3K3,ZNF462,ADAMTS2,CD55,CITED4,MOSPD2,SYNE2,PCTP,SPTLC2,SNX12,EDNRA,GPLD1,XKRX,DGKH,PITX2,ALDH5A1,TIMM8A,SFMBT1,NFKBIZ,EFNA5,PER3,TOB1,JARID2 |
| 5.160e-06 | -12.17 | positive regulation of phosphorylation | biological process | GO:0042327 | 1006 | 146 | 16441 | 1675 |
TXN,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PIK3CA,DLG1,RASGRP1,PLK1,PRKAR2B,CDK1,PLCG1,GPRC5B,ANKRD6,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,PRKAA2,PIFO,ITGA6,RASA2,SOX9,CALM3,TEC,IGF1R,CYR61,MAP3K9,MDFIC,PIM1,MYDGF,NCAM1,WNT3A,CCDC88A,MDFI,MMD,CALM1,PDE5A,STRADB,PSMA4,CDK5R1,RASA1,FAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,ST5,KIF14,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,AKT1,RIPK2,FZD4,CD40,MAP3K6,FZD7,IRS2,JAK1,STK26,SLC27A1,NRG1,SPTBN5,EFNA5,NKX3-1,PINK1,SDC4,PSMD10,GDF15,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,PSMB4,PLAUR,RAPGEF2,GRIN1,RGCC,YES1,BANK1,ACVRL1,FGFR2,RAP2C,RYK,ARRB1,GRIN2D,PPP2R3C,LRRK1,CENPE,GPER1,FZD5 |
| 5.195e-06 | -12.17 | RODRIGUES_NTN1_TARGETS_DN | MSigDB lists | RODRIGUES_NTN1_TARGETS_DN | 153 | 34 | 17758 | 1761 |
BIN1,PRSS8,GAA,SIGIRR,BCAM,PACSIN2,PAPSS2,HSPG2,SOX9,ARL4C,FBXO2,IER3,ADORA1,ITGA3,RRBP1,PIK3CA,CLDN4,MYH14,C10orf54,RAB27B,RBMS2,PCDH1,KIFC2,NR4A1,HTATIP2,KLK6,STK17B,SOX13,MMP15,PGF,TIMP3,PVRL2,LIMK1,CDK18 |
| 5.419e-06 | -12.13 | mouth | COSMIC cancer mutations | mouth | 9422 | 1019 | 17775 | 1757 |
HECA,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,AK7,DNAJC3,RET,CACNA2D2,DHX8,NRG2,LACTB2,CA8,BARD1,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,WEE1,PSMD1,PQLC2,AP1M2,KIAA1107,PAQR5,ALDH1A3,SEMA3G,MANF,PIK3CD,TMEM37,TIAM1,TIPARP,MGAT5,ERAP2,DNAAF3,NWD1,SPEF2,SMARCA2,FBXL16,MTRF1L,TMEM151A,TFAP2C,PRKAR2B,LOXL2,F12,COL12A1,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,DNM1L,ANKRD6,ATP7B,LIMK1,FAM114A1,NOD2,AGFG2,HDAC1,SERPINB6,TMOD2,ITPKA,GAB1,E2F8,HOXC13,NXT2,SCN5A,ALDH6A1,FAM169A,GGA1,ITGA6,SOX9,MTL5,SLC36A4,MERTK,FAM21C,TTYH3,LMNA,RAVER2,RABGGTA,TFAP4,FRY,MEGF8,RIMS3,FLRT3,MAP3K9,ALPK1,PANX2,ZMYM1,NCAM1,ULBP2,DGKG,NUP85,PPP6R1,C9orf72,PAQR7,HPS3,KIF20A,STAT4,MYBL2,ELK1,NPHP3,SPTLC2,SFXN5,GNA11,PLIN5,CYB5A,PTPRF,SCARB2,NCOA3,SLC4A4,ETS2,SEMA4D,SETD3,ITPR1,CLMN,AURKA,MDH1,NDE1,DRP2,ZNF502,TMEM173,XDH,ADAMTS16,DOCK9,ARHGAP11A,MTM1,TPRN,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PRSS22,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,REPS1,ZNF385B,CDS1,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,SP100,SH3BP1,DACT1,XYLT2,RTKN2,ACSL4,RASGEF1A,RAB27B,LRP11,DLG3,ZNF365,ETV4,MYT1,TMEM9,SCN3A,ENPP4,MX1,CAMSAP3,SSH3,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,PLEKHO1,SYNE2,HTATIP2,RAB38,DNAJB14,XRCC6BP1,ZNF618,NFIX,SHROOM3,CDK19,WFS1,CORO1C,SLC9A6,AXL,SIPA1L1,PLEKHG1,PNPLA6,RGS14,ISOC1,MAPK12,TTC8,TNRC6C,NKX3-1,ESRP1,HABP4,OSGIN2,BTN3A1,PDIA3,CTSZ,ANO9,PKN1,NUCB2,ETS1,SRPX2,NEO1,PDIA4,DTX3L,DIRAS3,CXCL16,ITGB8,IGSF9,SLC27A6,ANKS1B,CTSC,ARSG,CST3,KLC3,PLEKHF1,TMBIM6,IGFBP2,MAPK11,NPTXR,TPCN1,CRTAP,PARP9,AMOTL2,PVRL4,ADAMTS2,FAM160A1,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,CXorf57,AK4,SNTB1,CNTNAP1,GALNT3,PLOD2,ACVRL1,SYT7,CENPE,ITGAV,FHL1,OSR1,CMPK2,DCBLD1,CYBRD1,ACOT7,TLL2,ILDR1,BCAM,KIAA1462,EPAS1,PPM1J,GNPDA1,FAM199X,CNOT8,CUL4B,FHDC1,ARFGEF1,LMCD1,NDRG2,TEX2,MGAT5B,ITPR2,HDAC6,PDGFB,SDC1,SPTB,FANCI,SUSD2,BTG3,CPNE2,RPS6KA2,MKRN3,IL6ST,PAPSS1,SLC44A1,ELF5,MITF,TMEM143,ABCA2,NTN4,ANO4,TLN2,DDX59,NEB,ZNF462,PLK1,PCGF5,MCTP1,CD55,KCNIP3,CELSR2,EZR,CR2,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,DPYSL3,OPTN,KDM4D,TRIM9,PLEKHG6,MFAP3L,PLCH1,KCNMB4,MAP2,WIPI1,ZNF367,RAB11FIP1,PRKCDBP,ARRDC1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRSS8,PRKAA2,RUNX2,HJURP,HLA-F,CNTNAP2,NCKAP1,FBLN1,IL18R1,TNS3,DAZAP1,IGF1R,SPIN4,RINL,FRAS1,TBCD,AHCY,PIM1,FAR2,WNT3A,PLCB2,ALDH3A2,CKAP4,ABCC1,C9orf9,CYP26B1,CHSY3,DPYSL5,PCDH1,PLEKHA6,RGMB,TESK1,PCBP3,MGAT4B,SPATA13,SCRIB,EIF2AK1,PDK3,ANKRD29,G2E3,CDK5R1,PRX,RASGRP2,EPN3,MAPKAPK2,H1F0,COL13A1,KBTBD2,PHLPP2,ITGA7,MFSD2A,SLC2A6,NLRC5,LTBP2,PLD1,SEMA3A,CCNB2,RNF146,USP43,AVPI1,NF2,HOXB7,XYLT1,TP53,CCDC68,ERBB2,FAM198B,LPIN3,EMP2,STIL,CYP26A1,RAD23A,TTC21B,WDR44,LMO4,LHX6,PLCG2,SRR,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,NOTCH3,OAS3,EGLN3,SCN2A,CTDSP2,GM2A,DVL2,CTH,SULF2,CPD,SIRT1,MBP,AKT1,FIGNL1,PTGER4,DAG1,ATP13A2,DNAJC10,TAPBP,DUOX1,ATP1A1,IDE,C19orf66,RBL1,ABHD12,PTK7,STK38,ADAMTS14,IRF7,C1orf43,ST3GAL1,AIFM3,ZNF701,NDST3,MAN2B2,CMAS,COL9A3,PINK1,PACSIN2,TM2D2,CDH22,CPEB4,MACC1,RUSC2,HAL,GNE,CDCA8,GDF15,CRABP2,DSE,PARM1,PPP2R3A,SLC9A2,NRP2,SIRPA,SH2D4A,CD109,C16orf74,CDK16,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,ABCD1,KLF9,FAIM,SYK,TLE6,ATP2B1,GCNT1,IGDCC4,NFE2L3,DLGAP1,RHOA,FBLN5,MOSPD2,NR3C1,AMFR,PPARA,PRICKLE1,MAML2,GGH,COL7A1,FNDC3A,RNPEP,BCAR1,TXNDC11,MAPK8IP1,CD83,PRDX4,BANK1,SERPINA1,FAT4,TWSG1,SCG2,NMI,TMC5,NETO2,PGRMC1,FAM117A,ICOSLG,TBC1D4,UBE2C,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,DIS3L,LAMP1,SUN1,GAA,PPP4R4,LGR4,HSPG2,ATP8A1,TSC22D3,PPFIBP2,CAMK1D,PLXNA1,VASH1,OAT,PJA2,SLC20A1,FAM101B,NCS1,CYP1A1,SESN3,ANKS6,ZNF823,ELMO2,STIM1,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,ATRNL1,IQCD,HYLS1,MTMR11,PACSIN1,SMYD5,METAP2,LOC81691,SGCE,KIFC2,SPATA18,ACVR1C,PBK,HSPA12A,NBPF3,SLC35C1,KIF13A,TNS1,GALNT7,MCFD2,LDB2,CCNF,SPNS3,POR,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,LRIG1,NKD1,FAM110C,NFKBIZ,EIF4EBP2,TANC2,UNC5B,TRAF5,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,MRPL44,CDK17,TBC1D1,HLA-E,CALB2,SLC25A27,KIF23,ISYNA1,SLC1A3,PSIP1,KIAA1161,MECOM,DOPEY2,RALGPS2,LYPD3,PIK3AP1,SNX18,BHLHE41,VASN,AIM1,RUNDC3B,DAPK1,PRKG1,ADCK2,TPST1,SORL1,CD70,CACNA1D,C8orf58,PIKFYVE,SYTL3,RIMS2,TRAK2,IGSF3,EPB41L5,PMPCB,B3GNT7,KCNJ12,FADS2,MFI2,TBC1D8B,ADCK3,LPGAT1,AMER1,ANO6,PIP4K2C,FAM133B,NPC2,ATP8B3,ANTXR1,GLT8D2,RASA1,FRMD4B,MMP15,DGKH,GABRD,SLCO4A1,PRKAG2,PLEKHH2,TJP3,FAM64A,DCK,MATN2,SLC4A3,FAM83D,FGD6,SFMBT1,PCDH19,CABIN1,CDK18,KLK7,NR4A2,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,SLC2A4,REPS2,DLGAP5,ARMCX3,ST14,NLRX1,CCDC110,IQGAP1,CAST,RALBP1,DDIT4L,RPS6KA1,ATP2C2,BCL2L1,DDR1,MNS1,CYP39A1,ZFYVE9,EPS8L2,APLP2,ZNF75D,ACAP2,FAM46A,TRANK1,DOK4,CDKN1B,EPHB4,LGMN,PHKA2,SULT2B1,NR2C1,NAGA,ATG4D,GPX4,MYO5B,DOCK4,SEC23A,COG2,CAPN6,FOXJ2,UTRN,KIF1C,TMEM144,SLC11A2,PKMYT1,ATP1B1,C15orf39,ITPR3,ASB13,ALCAM,SP4,ZNF469,FZD7,PRDM11,NIN,AMZ2,EPHA10,JAK1,NGFRAP1,TRIOBP,FAM195A,SLC27A1,KLF5,SLC27A3,NR3C2,COBL,DENND5B,PCOLCE,DEPDC1,ATP9A,EPS8,CCNJL,HERC5,PBX3,CYB561,APOBEC3H,DNAH3,SIX4,HLA-A,LGALS3BP,SLC25A36,WWP2,RASSF8,E2F7,FAM111A,PTEN,FUT8,DRAM1,SLC44A2,TAGLN2,ERBB3,CNOT6L,TRIM62,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ALDH2,ARAP2,LONRF3,ZC3H11A,PARP4,ZKSCAN2,FURIN,DIAPH2,YES1,LRRC1,FOS,CDK5RAP1,MAMDC4,ACADSB,FGFR2,TBX18,AMMECR1,ABCB1,PGM2L1,CSTF2,GRIN2D,ETAA1,WDR62,ARSB,ESPL1,MELK,OCLN,JARID2,RGMA,ESYT2,EXPH5,LTBP1,UGT8,HEBP1,CPT2,VARS2,KREMEN1,TMC1,TSEN34,CHPF,ABCD4,ARHGEF10L,EPCAM,ZFYVE16,SIPA1L2,HSF2,LRRC6,ARHGEF37,SIVA1,ANKFN1,CEP78,DLG1,POF1B,ANKRD12,TRPC1,RAB20,CTTN,MYH14,PTPRE,MYRIP,RASGRP1,NLRP4,ATL1,TRIM8,USP18,ITCH,RGAG1,ROR1,PTGFRN,CXXC4,MAN2A2,LRRC42,ARHGEF19,GPRC5B,UEVLD,MADD,ADIPOR1,SP6,GLA,RAP1GAP,PCSK5,NR2C2,GRN,ARAP3,ZNF395,LRRFIP2,SERPINE2,PEX6,PYROXD2,ETV5,SAMD9,FAM81A,PHLPP1,ADAMTSL4,B3GALNT1,ZNF432,KCNN4,COL6A1,FXYD5,LIMCH1,RFX5,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,ELK3,PODXL2,OXR1,GYLTL1B,VWA1,PDE5A,HMG20B,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,MUM1L1,SOX13,GLCE,GNAS,BCAR3,FECH,UAP1,CDCA5,ALPK3,RHOBTB2,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,PROM2,KLF7,CCNE2,LMO7,GAS2L1,NCKAP5,LZTFL1,SLC25A24,SORBS1,PSME2,HDAC11,PDIA5,MORC4,COL18A1,TDRKH,OSR2,PHLDA1,KCTD9,LRRC45,SS18,SLC25A48,ZNF687,SETDB2,CYP4F11,ZDHHC12,FRYL,DIXDC1,EPB41L4B,SCYL3,FRS3,SEPHS1,MAP3K3,PTPRU,SLC39A8,OSTM1,C3orf52,IGSF8,GLO1,ERBB2IP,CD40,DUSP4,DOCK5,MAP3K6,CASP4,ARHGAP35,BFSP1,BHLHB9,OVOL1,SPTBN5,CYP2U1,ABCA1,PPP2R2D,LIFR,FBLIM1,ARHGEF11,TSPAN15,FRMD6,POC1B,LRP4,FAM134A,COL4A5,TRMT2B,POMGNT1,SBF1,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,MLPH,A4GALT,BMP7,RRBP1,GALNS,KIAA0319,ARVCF,IQGAP3,CLIP2,MYO5A,B3GALT6,PGM1,PHF20L1,RAB3B,NR4A1,ASPM,RC3H2,OGDHL,LRRC66,TTC7A,LEPR,KLHL2,ENDOD1,HLA-B,TRIM69,HNRNPH2,DHRS2,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,PLOD3,SOX8,GEM,L1CAM,RAB3IL1 |
| 5.432e-06 | -12.12 | immune response-regulating cell surface receptor signaling pathway | biological process | GO:0002768 | 463 | 78 | 16441 | 1675 |
SPRED1,INPP5D,PSME2,ERBB2,NRG2,PSME1,ITPR2,PRKACA,CACNB4,PDGFB,SPTB,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,PDE4D,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,CASP9,CR2,AGO4,PRKCQ,CD40,ITPR3,IRS2,PLCG1,PTPRJ,JAK1,LIMK1,SPTBN5,NRG1,GAB1,TNRC6C,THEMIS2,RASA2,PSMD10,BTN3A1,CALM3,TEC,NCKAP1,PHLPP1,FGF19,PTEN,BAX,ERBB3,NCAM1,SYK,RASGRF1,PSMB4,NR4A1,MICB,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,FOS,BCAR1,PSMA4,RASA1,GPLD1,FGFR2,PHLPP2,ITPR1,NFKBIA,NR4A3,GRIN2D,ARPC2,JAK3 |
| 5.592e-06 | -12.09 | enzyme regulator activity | molecular function | GO:0030234 | 904 | 133 | 16491 | 1673 |
CASP3,PPP4R4,DNAJC3,ARFGEF1,PSME1,PDGFB,CDKN2C,CALM2,SIPA1L2,PSMD1,RGS3,CABP1,PIK3CA,RP2,RCAN3,CASP9,ARHGDIB,PRKAR2B,PIF1,PRKRA,PPP1R14C,ABR,PLEKHG6,ARHGEF19,GPRC5B,MADD,CAB39,AGFG2,SERPINI1,SERPINB6,RAP1GAP,HSPB1,ARAP3,SERPINE2,PPP1R2,CDKN1C,TBC1D1,RASA2,CALM3,GPSM2,FBLN1,BMP2K,RINL,PPP4R1,RANBP1,FAM13B,TBCD,ALS2CL,TBC1D8B,CALM1,RASA1,CDK5R1,MMP15,PRKAG2,SH3BP4,CTSA,CABIN1,ATP1B3,SERPINB1,ARHGAP11A,CCNE2,SPRED1,RALBP1,RPS6KA1,CAST,IQGAP1,PSME2,PTTG1,RGS20,TP53,MGST2,CCND1,APLP2,ACAP2,SH3BP1,CDKN1B,DAB2IP,CDKN2D,GM2A,CHP1,CKS2,DOCK4,TIMP2,AKT1,ATP1B1,ARHGAP35,SOCS3,DNAJC10,PPP2R5A,NGFRAP1,MMP17,SIPA1L1,EFNA5,NRG1,RGS14,PPP2R2D,GCLM,ANXA3,PINK1,NKX3-1,PCOLCE,DEPDC1,ARHGEF11,TRIB2,SBF1,GSTP1,PPP2R3A,CD109,CARD8,CTSC,LLGL2,CST3,TMBIM6,ERBB3,IQGAP3,SPRY2,ARAP2,RAPGEF2,PIK3R1,RGCC,FURIN,COL7A1,GRTP1,MAPK8IP1,ARHGAP24,CDK5RAP1,TIMP3,SERPINA1,SPINT2,ARRB1,TBC1D4,CPEB2,PKIA |
| 5.624e-06 | -12.09 | negative regulation of programmed cell death | biological process | GO:0043069 | 835 | 125 | 16441 | 1675 |
CASP3,TSC22D3,RPS6KA1,CAST,DNAJC3,PSME2,TP53,ERBB2,PSME1,BCL2L1,CAMK1D,BARD1,STIL,IER3,EPCAM,PSMD1,IL6ST,KIF14,IL31RA,PLCG2,MITF,BCL6,PIK3CA,CDKN1B,TWIST1,CTTN,SLC39A10,LGMN,CDKN2D,F2R,CTH,PLK1,PPIF,SIRT1,RIPK2,AKT1,FIGNL1,ITCH,HTATIP2,GLO1,PRKCQ,SLC25A5,CDK1,POR,ARF4,OPTN,SOCS3,IRS2,MDK,SLC25A4,BHLHB9,PLK2,WFS1,AXL,MADD,NOD2,TLE1,HDAC1,IRF7,NRG1,UNC5B,HSPB1,LIFR,PRKAA2,GCLM,PINK1,BMF,CPEB4,LGALS3,ITGA6,SOX9,SLC25A27,PSMD10,TGFBR1,GSTP1,MERTK,LMNA,SIX4,MECOM,ADORA1,IGF1R,CYR61,PTEN,BMP7,DAPK1,BAX,TFAP2A,TMBIM6,PIM1,MYDGF,ERBB3,CITED2,FAIM,SPRY2,RHOA,PSMB4,PLAUR,GCLC,OXR1,PIK3R1,GRIN1,STRADB,PELI3,IFIT3,PSMA4,MAPK8IP1,G2E3,RASA1,FAS,FGFR2,SEMA4D,SCG2,DHRS2,NFKBIA,NR4A3,AURKA,ARRB1,NR4A2,ITGAV,SOX8,OSR1,JAK3,RARG,HIPK3,IFI6 |
| 5.646e-06 | -12.08 | TSAI_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | TSAI_RESPONSE_TO_IONIZING_RADIATION | 147 | 33 | 17758 | 1761 |
GRN,CCNE2,CCNI,NFKBIE,CDKN1C,LGALS3,RPS6KA1,TSC22D3,PTTG1,GDF15,PLCG2,RANBP1,COL6A1,SGK1,RFX5,MDFI,PLK1,TGIF1,DDB2,NFE2L1,CCNF,CDK1,TP53I3,DPYSL3,CD83,FAS,NCOA3,AXL,NFKBIA,NR4A3,PLOD3,UBE2C,AHR |
| 5.736e-06 | -12.07 | GSE7852_TREG_VS_TCONV_THYMUS_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_UP | 194 | 40 | 17758 | 1761 |
CCDC109B,TTC39B,LGALS3,BCL2L1,PHLPP1,IL18R1,PPP2R3A,IGF1R,ITGB8,OSBPL3,MDFIC,NTN4,TSPAN13,KLF9,PIM1,MGAT5,S100A6,IGSF3,GCNT1,TGIF1,PLSCR1,PTPN9,S100A4,MBNL3,PTGER4,DUSP4,PRKRA,PCTP,RNPEP,CASP4,SPNS3,GABARAPL1,CD83,HLA-B,PRKAG2,NR4A2,SH3BGRL2,GEM,AHR,ACOT7 |
| 5.798e-06 | -12.06 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 279 | 52 | 17758 | 1761 |
CCNE2,PAPSS2,DLGAP5,IL15,NDC80,KIF23,NUF2,CD274,PM20D2,FANCI,SCML1,TOP2A,RCN1,CTSC,NPNT,DPYSL2,CALD1,SLC44A1,DRAM1,MINPP1,GAD1,MPHOSPH9,CKAP4,SOCS5,NFE2L3,DOCK4,PHF20L1,ADAMTS2,ZWINT,ZNF84,FIGNL1,PBK,EIF5A2,VEZT,NUSAP1,ANLN,CCNF,IDH1,KIF11,ANKRD29,CDK1,FZD7,FAS,TWSG1,ZNF367,NFKBIA,ERAP1,CENPE,ITGAV,NDE1,IFIH1,MELK |
| 5.822e-06 | -12.05 | ST_GAQ_PATHWAY | MSigDB lists | ST_GAQ_PATHWAY | 28 | 12 | 17758 | 1761 |
PITX2,NFKBIE,ADRBK1,AKT1,NFKBIA,ITPR1,ITPR2,PLD1,PHKA2,ITPKA,ITPR3,DAG1 |
| 5.857e-06 | -12.05 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | 103 | 26 | 17758 | 1761 |
CPD,CDKN1C,ATP9A,ZCCHC24,RC3H2,PIK3R1,LOXL2,ATP1B1,NFIB,CYP39A1,PARM1,NEO1,ENDOD1,SESN3,FAT4,FGFR2,SNX18,PTK7,PLEKHG1,CENPE,TINAGL1,MYBL1,SLC27A3,SLC12A2,PCSK5,SEMA3B |
| 5.857e-06 | -12.05 | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | MSigDB lists | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | 103 | 26 | 17758 | 1761 |
BIN1,ACACB,CELSR2,NR3C1,DNAJB2,SNTB2,ITPR2,B4GALT4,GNA11,CYP4F3,KCTD9,NEO1,CCDC92,ADD3,SERPINA1,CTGF,LLGL2,PASK,TRPC1,DHTKD1,ACOX2,CDKN2D,HSPB1,ZNF701,RRAGD,SEMA3B |
| 5.871e-06 | -12.05 | TAZ (tafazzin) | protein interactions | 6901 | 90 | 25 | 16036 | 1726 |
ADAMTS2,COL6A2,MFI2,GUSB,HAPLN3,PLAUR,HLA-F,GYLTL1B,CACNA2D2,COL18A1,LOXL2,GALNT7,PLXNA1,ARSK,NRP2,CD109,ITGA7,FRAS1,BMP7,MEGF8,XYLT2,GALNS,ITGAV,NAGA,TMEM131 |
| 5.955e-06 | -12.03 | RODWELL_AGING_KIDNEY_UP | MSigDB lists | RODWELL_AGING_KIDNEY_UP | 445 | 74 | 17758 | 1761 |
LAMP1,PSME2,RPS6KA1,TAP1,MRAS,FAM198B,VASH1,FAM101B,TMPRSS4,SYTL2,NOV,TYMP,PIK3CD,TSPAN1,PTPRE,SULF2,TIMP2,PLEKHO1,HTATIP2,ARHGDIB,C15orf39,ITPR3,CMTM7,SOCS3,NFIX,TAPBP,CARHSP1,CORO1C,AXL,TSPAN18,NFKBIZ,REEP4,GRN,DDX58,SCN5A,CTHRC1,LASP1,RUNX2,PARP12,SERPINE2,NUAK1,HLA-F,ZCCHC24,HLA-E,DGKQ,ARL4C,SAMD9,SLC1A3,HLA-A,PDIA4,DTX3L,CXCL16,BHLHE41,DRAM1,FXYD5,ARVCF,TAGLN2,C10orf54,HLA-C,CCDC88A,ABCC1,DLGAP1,NUB1,PRICKLE1,RUNX3,ANTXR1,FAS,HLA-B,SLC6A6,RPL12,NLRC5,PGM2L1,PLOD3,TMEM173 |
| 5.960e-06 | -12.03 | V$E4F1_Q6 | MSigDB lists | V$E4F1_Q6 | 272 | 51 | 17758 | 1761 |
CCNI,LTBP1,MRC2,TSC22D3,SOX9,HABP4,RAB6A,GRK6,MORF4L2,HDAC6,CHPF,IRF2BPL,AKIRIN1,CXCL16,ZNF687,CYR61,ANKS1B,SHC3,CALD1,DACT1,FLRT3,FOSB,PLK4,TRPC1,CRY2,TSPAN13,RFX5,ARL4D,ARMCX6,RBMS2,WBP5,ZNF462,NR3C1,NR4A1,PELI3,TP53INP2,ATP10D,FZD7,ARF4,PITX2,GNAS,COQ10A,PDLIM3,SCG2,ZNF367,NR4A3,NR4A2,GEM,OSR1,MAFF,RUSC1 |
| 6.016e-06 | -12.02 | cell projection part | cellular component | GO:0044463 | 893 | 130 | 17570 | 1756 |
EPHA4,FBXO2,NDRG2,TMC1,GRM5,CALM2,DPYSL2,DLG1,AKR1B1,TUBG1,RP2,MYH14,CTTN,PACSIN1,ORAI2,SPEF2,SGCE,EZR,PRKAR2B,ARF4,DZIP1L,DPYSL3,MAP2,TRAF3IP1,TMOD2,PIEZO1,ITPKA,ARF6,NRGN,LZTS1,DDX58,PIFO,BVES,CALB2,CALM3,NCKAP1,SLC1A3,CNTNAP2,DHRS3,ITGA3,SNX18,FLRT3,EXOC8,GPR161,EPB41L5,CALM1,SPATA13,ELK1,NPHP3,ANTXR1,CDK5R1,STX3,RASGRP2,PHLPP2,AURKA,CFAP20,EHD1,PROM2,DYNLRB1,TCTN2,NF2,IQGAP1,C5orf30,APC2,PRKACA,MNS1,EPS8L2,TTC21B,SCNN1A,ESPN,GOT1,DAB2IP,DLG3,SCN2A,CLCN3,MBP,TIMP2,AKT1,SEPT6,CYS1,CCSAP,SYNE2,UTRN,SLC11A2,DAG1,CEP162,GABARAPL1,ATP1A1,PTPRJ,SLC9A6,SIPA1L1,NRG1,SPTBN5,RGS14,COBL,BIN1,TTC8,PACSIN2,POC1B,EPS8,GABRG2,DNAH3,KIF5B,ADD3,ADORA1,ANKS1B,PTEN,KLC3,ATP8B1,SPRY2,MYO5A,DLGAP1,RASGRF1,RHOA,LCA5,CFAP46,PLAUR,GRIN1,STMN3,AIF1L,BBS2,CNTNAP1,SYT7,ARRB1,GPER1,ITGAV,CEP41,L1CAM,CYBRD1,ARHGEF4 |
| 6.048e-06 | -12.02 | LI_INDUCED_T_TO_NATURAL_KILLER_UP | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_UP | 294 | 54 | 17758 | 1761 |
LASP1,ARAP3,LGALS3,SERPINE2,S100A11,CD63,ASAH1,VASH1,IL18R1,LGALS3BP,SYTL2,LMNA,IER3,PDGFA,DAPK2,AIM1L,FAM46A,CTGF,SNX18,OSBPL3,PLCG2,AIM1,FAM63A,CD9,FXYD5,SGK1,OSTF1,TIAM1,F2R,SULT2B1,S100A13,S100A6,SMAGP,GCNT1,SUSD3,SYPL1,SEC61B,PLSCR1,IFITM3,S100A4,LITAF,FURIN,PRDX4,ENDOD1,CORO1C,SLC2A6,SERPINB6,MLKL,LRRK1,TMEM120A,ARF6,ARSB,NRGN,NDFIP1 |
| 6.049e-06 | -12.02 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | 174 | 37 | 17758 | 1761 |
IL15RA,IL15,TRIP10,SAMD9,CD274,HERC6,BTG3,ITGB8,DRAM1,SELK,IFIT1,RASGRP1,LAMP3,ARAP2,RIPK2,TNIP1,PLAUR,STAT4,RAPGEF2,LYRM1,PTGER4,IFIT3,SOCS3,GALNT3,MFSD2A,NFKBIA,NR4A3,NETO2,NFKBIZ,IRF7,NR4A2,HS3ST3B1,GEM,CMPK2,IFIH1,KLF7,EHD1 |
| 6.133e-06 | -12.00 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1159 | 160 | 17775 | 1757 |
HSPG2,SLC25A13,RET,SPTB,SLC9A7,CALM2,TYMP,WEE1,SIPA1L2,RPS6KA2,PQLC2,MUC4,PAPSS1,DLG1,PIK3CA,ANKRD12,SEMA3G,ACOX2,PIK3CD,MYBL1,ERAP2,ZNF462,SMARCA2,TNIP1,SERTAD4,PBK,PRKRA,IDH1,MAP2,PLK2,ATP7B,MADD,PRKCDBP,PIK3C2B,TANC2,HOXC13,MRC2,RUNX2,CDK17,ZNF395,CHCHD7,IGF1R,FRAS1,DAPK1,PRKG1,OPN3,MAP3K9,PIM1,CACNA1D,PIKFYVE,ALDH3A2,MPHOSPH9,ADCK3,PIP4K2C,SPATA13,BTN3A2,EIF2AK1,PDK3,NFIB,MAPKAPK2,SEMA4D,DCK,FGD6,AURKA,MAP3K5,JAK3,TOB1,ADAMTS16,MFSD3,SLC25A24,TRIP10,CAST,RPS6KA1,THRA,TP53,ERBB2,GRK6,PRKACA,DDR1,APPBP2,MUC16,SP100,LHX6,BRI3,EPHB4,DLG3,LRP11,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,AKT1,COG2,CAPN6,SYNE2,UTRN,ERBB2IP,ATP1B1,MAP3K6,NFIX,DUOX1,PTPRJ,JAK1,CDK19,AXL,STK38,PTK7,OVOL1,IRF7,KLF5,AIFM3,LIFR,ABCA1,MAPK12,PINK1,TNRC6C,CENPI,GNE,FAM134A,NOTUM,SEPP1,TMEM63A,NEO1,KIF5B,DIRAS3,FOXP2,ITGB8,PTEN,CDK16,MGAT4A,TFAP2A,SGK1,MAPK11,IGFBP2,ERBB3,SYK,SUN2,ARAP2,B3GNT2,ARHGEF28,ELOVL3,PIK3R1,ZKSCAN2,AK4,MAML2,COL7A1,YES1,RNPEP,MAPK8IP1,FAT4,FGFR2,CENPE,OSR1,ZMIZ1,TBC1D4,ESPL1,L1CAM,MELK |
| 6.249e-06 | -11.98 | negative regulation of cell death | biological process | GO:0060548 | 894 | 132 | 16441 | 1675 |
CASP3,TXN,TSC22D3,DNAJC3,PSME1,CAMK1D,BARD1,EPCAM,PSMD1,CTGF,IL6ST,IL31RA,MITF,PIK3CA,CTTN,SLC39A10,PLK1,ITCH,SLC25A5,CDK1,POR,ARF4,OPTN,MDK,SLC25A4,PLK2,MADD,NOD2,HDAC1,UNC5B,HSPB1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,SLC25A27,MERTK,LMNA,MECOM,IGF1R,CYR61,DAPK1,SORL1,PIM1,MYDGF,OXR1,STRADB,IFIT3,PSMA4,G2E3,RASA1,FAS,SEMA4D,NFKBIA,AURKA,NR4A2,CABIN1,JAK3,RARG,IFI6,PSME2,CAST,RPS6KA1,TP53,ERBB2,BCL2L1,STIL,IER3,NOV,KIF14,PLCG2,BCL6,CDKN1B,TWIST1,LGMN,F2R,CDKN2D,CTH,SIRT1,PPIF,AKT1,RIPK2,FIGNL1,HTATIP2,PRKCQ,GLO1,SOCS3,IRS2,BHLHB9,AXL,WFS1,TLE1,NRG1,IRF7,LIFR,GCLM,PINK1,CPEB4,PSMD10,TGFBR1,GSTP1,SIX4,ADORA1,PTEN,BMP7,CST3,TFAP2A,BAX,TMBIM6,ERBB3,FAIM,CITED2,SPRY2,RHOA,PSMB4,GCLC,PLAUR,PIK3R1,PPARA,GRIN1,PELI3,MAPK8IP1,SCG2,FGFR2,DHRS2,NR4A3,ARRB1,ITGAV,OSR1,SOX8,HIPK3 |
| 6.252e-06 | -11.98 | TGFB_UP.V1_DN | MSigDB lists | TGFB_UP.V1_DN | 181 | 38 | 17758 | 1761 |
DDX58,NUDT6,UGT8,AVPI1,ZNF395,LGR4,HSPG2,GNE,OSR2,HSF2,PAQR5,MITF,TFAP2A,BCL6,ATRNL1,CDKN1B,PLEKHF1,IFIT1,MINPP1,CITED2,MYBL1,SPRY2,RIMS2,FRS3,RASGRF1,PCBP3,SYBU,PTGER4,RAB38,DUSP4,IFIT3,SAV1,PRX,FRMD4B,AP1AR,RBM47,RAB11FIP2,OTUB2 |
| 6.335e-06 | -11.97 | MODULE_212 | MSigDB lists | MODULE_212 | 324 | 58 | 17758 | 1761 |
PRSS8,NQO1,UGP2,BLVRB,HAL,HEXB,PDIA3,KIF23,MGST2,OAT,CYP26A1,PDIA4,TOP2A,CYP1A1,CA2,CTSC,METTL7A,PLCG2,DAPK1,PCYOX1,TMBIM6,GOT1,RAB20,ALDH7A1,ACOX2,MANF,PIM1,ARL4D,MCCC2,FAH,ABCC1,PLK1,FADS2,IFITM3,MPP1,SAT1,ACO1,FURIN,STRADB,GGH,GLO1,TNS1,F12,MCFD2,IDH1,CDK1,CYB5A,PRDX4,DPYSL3,FUCA1,ENPP1,ACADSB,RND3,NAT1,MDH1,NRG1,MELK,XDH |
| 6.414e-06 | -11.96 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 188 | 39 | 17758 | 1761 |
CD63,TSC22D3,HABP4,PSME1,C3orf18,HOXB2,EPS8L2,ADORA1,ATP5H,KLF3,PASK,AIM1,SORL1,PIM1,SMAGP,CKAP4,ADCK3,STAT4,S100A4,CXorf57,CBX6,RNF113A,NPC2,PYGO1,ALCAM,ENDOD1,FUCA1,GABRD,SERPINA1,WFS1,LRIG1,FAM117A,MAP3K5,LTA4H,TBC1D4,NR3C2,APOL2,SNPH,DOCK9 |
| 6.414e-06 | -11.96 | GSE10325_BCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_BCELL_VS_MYELOID_DN | 188 | 39 | 17758 | 1761 |
LGALS3,CDKN1C,BLVRB,HEXB,KCTD12,SIRPA,GNS,DRAM1,DAPK1,MTMR11,FAR2,PTPRE,NAGA,CCDC88A,CYP1B1,CPD,LAMP2,ALDH2,TRIM8,S100A4,MPP1,PLAUR,SAT1,CDA,PDK3,BLVRA,C15orf39,RNPEP,FOS,CRISPLD2,SERPINA1,PELI2,SECTM1,NOD2,ZDHHC7,CTSA,SLC27A3,CYBRD1,RRAGD |
| 6.414e-06 | -11.96 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | 188 | 39 | 17758 | 1761 |
PLA2G4A,PARP12,IL15RA,IL15,PSME2,HLA-E,HLA-F,TAP1,SELL,HERC5,PSME1,LGALS3BP,RCN1,AIM1,OAS3,PIM1,TLN2,SNX10,APOBEC3G,ERAP2,FAM69A,MX1,SLC37A1,IFITM3,RAPGEF2,UBE2A,CD40,IFIT3,RNF19B,PSMA4,FAS,NMI,SECTM1,PRPS2,NOD2,IRF7,IFIH1,ISOC1,APOL2 |
| 6.414e-06 | -11.96 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | 188 | 39 | 17758 | 1761 |
GAS2L1,NKX3-1,ZNF395,OSGIN2,TDRKH,MGST2,DSE,OAT,FZD6,LMNA,ZFP36,N4BP3,FAM102A,LGMN,CPD,SYPL1,PLEKHA6,ELK3,ADCK3,SLC39A8,PTGER4,KIF13A,RUNX3,ASB13,SESN1,LEPR,RASA1,GABARAPL1,PLCH1,NEIL1,PLK2,MATN2,ABCB1,PRKCDBP,ADIPOR1,PPP2R3C,MAFF,TOB1,PKIA |
| 6.537e-06 | -11.94 | FUJII_YBX1_TARGETS_DN | MSigDB lists | FUJII_YBX1_TARGETS_DN | 195 | 40 | 17758 | 1761 |
SPC25,FAM169A,DEPDC1,FOXM1,DNAJC3,KIF23,CENPN,FANCI,TOP2A,E2F7,CXCL16,MDM1,MGAT4A,BMP7,PLK4,MYBL1,TIAM1,MPHOSPH9,CLCN3,ZWINT,ELK3,FIGNL1,ASPM,MICB,MYBL2,NUSAP1,PRKAR2B,CCNF,KIF11,H2AFV,PRIM1,TIMP3,TIMM8A,TWSG1,ZNF367,ITPR1,EIF4EBP2,NCAPG2,PTGES,MELK |
| 6.537e-06 | -11.94 | GSE7852_LN_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_DN | 195 | 40 | 17758 | 1761 |
TXN,KIAA1462,S100A11,IQGAP1,CYB561,KCTD12,BCL2L1,BEX2,MECOM,PLS3,IER3,BTG3,RNF128,SLC16A6,FOSB,SORL1,MDFIC,AHCY,TAGLN2,KLF9,TMEM64,SEMA3G,NR4A1,PTPN9,CORO2A,S100A4,RUNX3,PRKRA,RNF19B,C3orf58,STX3,DGKE,SLCO4A1,NGFRAP1,ABCB1,NR4A2,NFKBIZ,LRRK1,FHL1,TOB1 |
| 6.537e-06 | -11.94 | GSE7852_LN_VS_FAT_TREG_DN | MSigDB lists | GSE7852_LN_VS_FAT_TREG_DN | 195 | 40 | 17758 | 1761 |
CD99,IER5L,IQGAP1,KIF23,PBX3,PHLDA1,TNFSF9,BEX2,DNAJB9,IER3,OSBPL3,MITF,DRAM1,RAB20,TMEM64,NCEH1,RASGRF1,TGIF1,ADCK3,FZD4,RAPGEF2,MGAT4B,SYNE2,PRKAR2B,ALCAM,CARHSP1,HLF,MID1IP1,AGPAT2,ETS2,NR4A3,PCDH19,PRKCDBP,GRAMD1C,RELL1,FZD5,L1CAM,COL16A1,TOB1,MAFF |
| 6.594e-06 | -11.93 | VANHARANTA_UTERINE_FIBROID_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_DN | 63 | 19 | 17758 | 1761 |
LTBP1,NR3C1,EZR,NFIB,LEPR,KLHL2,ADD3,GATA2,WFS1,BCL6,DAPK1,ERAP1,KLF5,MDFIC,NR4A2,CITED2,MAP3K5,CBX7,MAFF |
| 6.650e-06 | -11.92 | head_neck | COSMIC cancer mutations | head_neck | 16165 | 1646 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,PAQR7,HPS3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ARRDC1,KLF11,RRAGD,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,MARCH2,ARMCX6,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,ATP8B3,ANTXR1,NFIB,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,LMO7,CCNE2,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,NKAPP1,MAPK11,WWP1,NPTXR,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,C15orf39,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,OXR1,GYLTL1B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 6.743e-06 | -11.91 | response to growth factor | biological process | GO:0070848 | 765 | 116 | 16441 | 1675 |
CASP3,SPRED1,RPS6KA1,PSME2,IQGAP1,TP53,NRG2,ERBB2,F11R,PSME1,ITPR2,HDAC6,PRKACA,PDGFB,SPTB,ARHGEF16,ZFYVE9,CALM2,PDGFA,ZFYVE16,PSMD1,ACAP2,RPS6KA2,CTGF,SHC3,ZCCHC12,PIK3CA,CDKN1B,DAB2IP,TWIST1,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,AGO4,PRKAR2B,ITPR3,DUSP4,ABR,IRS2,PLCG1,JAK1,NGFRAP1,RBL1,HDAC1,SPTBN5,NRG1,HSPB1,GAB1,FGD1,PCSK5,MAPK12,ANXA3,ARHGEF3,RUNX2,SORT1,TNRC6C,ARHGEF11,RASA2,SOX9,LRP4,CALM3,PSMD10,TGFBR1,GDF15,PHLPP1,FGF19,NRP2,ADRBK1,PTEN,MEGF8,BMP7,FLRT3,FUT8,MAPK11,C10orf54,ERBB3,NCAM1,SPRY2,EPB41L5,TGIF1,RASGRF1,RHOA,PSMB4,RGMB,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,FURIN,RUNX3,YES1,ELK1,FOS,BCAR1,PSMA4,RASA1,MAPKAPK2,FGFR2,TWSG1,ACVRL1,PHLPP2,ITPR1,NFKBIA,GRIN2D,LTBP2,JAK3,ARHGEF9,ARHGEF4,RGMA,EHD1 |
| 6.794e-06 | -11.90 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 470 | 77 | 17758 | 1761 |
TTC39B,CAST,NDC80,ITPR2,GRK6,CACNB4,KBTBD11,FAM46C,SH3KBP1,SP100,IL6ST,KLF3,BCL6,CDKN1B,IRF2,TMEM64,MGAT5,SPEF2,SGCE,SYNE2,PTGER4,UTRN,PRKCQ,PRKAR2B,IDH1,SESN1,STK17B,ENPP1,PLCG1,JAK1,CDK19,RBL1,AXL,LRIG1,INPP4B,NFKBIZ,LTA4H,GLCCI1,F2RL1,ARHGEF3,CDK17,ITGA6,UBASH3B,SELL,TRIB2,ETS1,PARM1,PRRG4,ADD3,ECI2,TSPAN13,MDFIC,CNOT6L,CITED2,ATP2B1,FAM69A,ELK3,B3GNT2,FBLN5,STAT4,PIK3R1,MRS2,LRRC66,HEATR5A,IFIT3,FRMD4B,FAS,NCOA3,NR4A3,DTX4,NR4A2,ATP1B3,MAP3K5,TBC1D4,AHR,ESYT2,JARID2 |
| 6.821e-06 | -11.90 | SWEET_KRAS_TARGETS_UP | MSigDB lists | SWEET_KRAS_TARGETS_UP | 80 | 22 | 17758 | 1761 |
LAMP2,MYL9,SERPINE2,HSPG2,NUAK1,DNAJB2,TNS1,COL7A1,GABARAPL1,ST5,TIMP3,JAK1,P4HA2,CALD1,MATN2,BMP1,INPP4B,SGK1,CLDN4,ITGAV,ECE1,HSPB1 |
| 6.882e-06 | -11.89 | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | MSigDB lists | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | 110 | 27 | 17758 | 1761 |
GCLM,PDGFC,ILDR1,SPC25,DLGAP5,ASPM,PBK,CDC20,EIF5A2,MYBL2,NUF2,PIF1,CCNB1,FOS,IER3,GALNT3,CYR61,CORO1C,LIMK1,ALG13,TBX18,PCYOX1,NEK2,AURKA,BUB1,TACSTD2,SPCS3 |
| 6.914e-06 | -11.88 | TAP binding | molecular function | GO:0046977 | 7 | 6 | 16491 | 1673 |
HLA-B,TAPBP,HLA-C,HLA-F,HLA-A,TAP1 |
| 6.937e-06 | -11.88 | ZHANG_TLX_TARGETS_60HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_60HR_UP | 288 | 53 | 17758 | 1761 |
GRN,SORBS1,HSPG2,CPEB4,NQO1,S100A11,THRA,HEXB,ARL4C,TAP1,LMCD1,SEPP1,LTBP3,SIRPA,PARM1,PDGFA,SIPA1L2,DOPEY2,RALGPS2,CST3,OPN3,AOX1,BAX,PLEKHF1,RFX5,LGMN,CITED2,PTPRE,S100A13,IGDCC4,SULF2,PDGFC,TIMP2,ELK3,PQLC3,PRSS23,NR4A1,S100A4,SAT1,NFE2L1,FOS,TP53INP2,GABARAPL1,FUCA1,SCARB2,SLC6A6,WIPI1,CSF1,SLC4A3,BMP1,PER3,TOB1,CPPED1 |
| 6.970e-06 | -11.87 | EF_Hand_1_Ca_BS | interpro domains | IPR018247 | 175 | 37 | 18293 | 1814 |
MYL9,SLC25A24,REPS2,S100A11,CALB2,CALM3,NUCB2,S100A2,HPCAL4,REPS1,NCS1,PPP2R3A,PLS3,CALM2,RCN1,CABP1,DGKG,RASGRP1,S100A6,GCA,KCNIP3,S100A4,CALM1,MCFD2,MYL12A,RASGRP2,PLCH1,PLCG1,DUOX1,NUCB1,GNPTAB,CGREF1,NKD1,S100A5,PPP2R3C,CAPN1,EHD1 |
| 7.069e-06 | -11.86 | death | biological process | GO:0016265 | 1112 | 158 | 16441 | 1675 |
LAMP1,CASP3,ADD1,RET,PSME1,SH3KBP1,DAPK2,RPS6KA2,PSMD1,CTGF,ELMO2,SIVA1,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,KLK6,STK17B,CDK1,POR,ABR,OPTN,SLC25A4,DNM1L,MADD,KLF11,UNC5B,ARF6,TRAF5,FGD1,BMF,SLC25A27,NCKAP1,PHLPP1,ADAMTSL4,TNFRSF19,LMNA,MECOM,TFAP4,CYR61,MAP3K9,DAPK1,SELK,TNFRSF12A,CD70,MYDGF,PIM1,WNT3A,PRODH,ERO1A,SCRIB,PSMA4,G2E3,FAS,STK17A,H1F0,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,TMEM173,XDH,PSME2,RPS6KA1,INPP5D,TP53,BCL2L1,AIFM2,PHLDA1,EMP2,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,CDKN1B,DAB2IP,SCN2A,EGLN3,F2R,CDKN2D,ATG4D,SIRT1,PPIF,MX1,EVA1A,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,EFNA5,MLKL,AIFM3,ZMAT1,GCLM,SORT1,NKX3-1,ARHGEF3,ARHGEF11,CKAP2,DAP,RASSF7,PSMD10,TGFBR1,PKN1,BEX2,SGPL1,TOP2A,CARD8,ADORA1,CTSC,PTEN,CST3,DRAM1,BAX,SGK1,ADAM15,TMBIM6,PLEKHF1,BUB1,ERBB3,FAIM,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,PARP4,LITAF,CTSL,FGFR2,TRIM69,CTSV,ARRB1,UACA,ITGAV,GPER1,FZD5,ARHGEF9,AHR,HIPK3,ESPL1,MELK,OCLN,ARHGEF4 |
| 7.069e-06 | -11.86 | cell death | biological process | GO:0008219 | 1112 | 158 | 16441 | 1675 |
LAMP1,CASP3,ADD1,RET,PSME1,SH3KBP1,DAPK2,RPS6KA2,PSMD1,CTGF,ELMO2,SIVA1,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,KLK6,STK17B,CDK1,POR,ABR,OPTN,SLC25A4,DNM1L,MADD,KLF11,UNC5B,ARF6,TRAF5,FGD1,BMF,SLC25A27,NCKAP1,PHLPP1,ADAMTSL4,TNFRSF19,LMNA,MECOM,TFAP4,CYR61,MAP3K9,DAPK1,SELK,TNFRSF12A,CD70,MYDGF,PIM1,WNT3A,PRODH,ERO1A,SCRIB,PSMA4,G2E3,FAS,STK17A,H1F0,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,TMEM173,XDH,PSME2,RPS6KA1,INPP5D,TP53,BCL2L1,AIFM2,PHLDA1,EMP2,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,CDKN1B,DAB2IP,SCN2A,EGLN3,F2R,CDKN2D,ATG4D,SIRT1,PPIF,MX1,EVA1A,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,EFNA5,MLKL,AIFM3,ZMAT1,GCLM,SORT1,NKX3-1,ARHGEF3,ARHGEF11,CKAP2,DAP,RASSF7,PSMD10,TGFBR1,PKN1,BEX2,SGPL1,TOP2A,CARD8,ADORA1,CTSC,PTEN,CST3,DRAM1,BAX,SGK1,ADAM15,TMBIM6,PLEKHF1,BUB1,ERBB3,FAIM,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,PARP4,LITAF,CTSL,FGFR2,TRIM69,CTSV,ARRB1,UACA,ITGAV,GPER1,FZD5,ARHGEF9,AHR,HIPK3,ESPL1,MELK,OCLN,ARHGEF4 |
| 7.147e-06 | -11.85 | MODULE_223 | MSigDB lists | MODULE_223 | 142 | 32 | 17758 | 1761 |
GRN,IL15RA,IL15,HLA-F,DNAJC3,EPS8,SELL,ERBB2,IL18,FTH1,PDGFB,EMP2,TNFSF9,HLA-A,PDGFA,CYR61,KCNN4,BCL6,TACSTD2,HLA-C,LAMP3,RUNX3,BCAR1,CDK5R1,CD83,EDNRA,MDK,HLA-B,P4HA2,CSF1,UBE2C,CAPN1 |
| 7.159e-06 | -11.85 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | 182 | 38 | 17758 | 1761 |
SIGIRR,HECA,TSC22D3,INPP5D,TMEM41B,EPHA4,TMX4,ARL4C,TRMT2B,TRIB2,FAM46C,DNAJB9,MARCH8,ADD3,FAM46A,LLGL2,LYPD3,MGAT4A,FOSB,PIK3CA,SORL1,SGK1,CRY2,MYLIP,TIPARP,SMAGP,ATP2B1,SUN2,PIK3R1,PTGER4,FOS,RASGRP2,IRS2,RAB11FIP2,KLF11,NR3C2,TOB1,KLF7 |
| 7.431e-06 | -11.81 | DELPUECH_FOXO3_TARGETS_UP | MSigDB lists | DELPUECH_FOXO3_TARGETS_UP | 69 | 20 | 17758 | 1761 |
TIMP2,CD55,KLK10,IGFBP6,PLAUR,SAT1,GNB5,IGF1R,CYR61,PLCG2,BCL6,PIK3CA,DAPK1,CD9,CLDN4,KLF5,ERBB3,MAP3K5,S100A13,GM2A |
| 7.584e-06 | -11.79 | SH3_domain | interpro domains | IPR001452 | 217 | 43 | 18293 | 1814 |
BIN1,LASP1,SORBS1,PACSIN2,TRIP10,MACC1,RUSC2,UBASH3B,EPS8,MPP5,TEC,CACNB4,ARHGEF16,SH3KBP1,EPS8L2,ARHGEF37,SNX18,FUT8,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,PLCG1,ARHGEF19,TJP3,SH3BP4,ARHGEF9,RUSC1,ARHGEF4 |
| 7.738e-06 | -11.77 | cellular response to growth factor stimulus | biological process | GO:0071363 | 743 | 113 | 16441 | 1675 |
CASP3,SPRED1,RPS6KA1,PSME2,IQGAP1,TP53,NRG2,ERBB2,F11R,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,ZFYVE9,CALM2,PDGFA,ZFYVE16,PSMD1,ACAP2,RPS6KA2,CTGF,SHC3,ZCCHC12,PIK3CA,CDKN1B,DAB2IP,TWIST1,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,AGO4,PRKAR2B,ITPR3,DUSP4,ABR,IRS2,PLCG1,JAK1,NGFRAP1,RBL1,HDAC1,SPTBN5,NRG1,HSPB1,GAB1,FGD1,PCSK5,MAPK12,ARHGEF3,RUNX2,SORT1,TNRC6C,ARHGEF11,RASA2,SOX9,LRP4,CALM3,PSMD10,TGFBR1,GDF15,PHLPP1,FGF19,NRP2,ADRBK1,PTEN,MEGF8,BMP7,FLRT3,FUT8,MAPK11,C10orf54,ERBB3,NCAM1,SPRY2,EPB41L5,TGIF1,RASGRF1,RHOA,PSMB4,RGMB,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,FURIN,YES1,ELK1,FOS,BCAR1,PSMA4,RASA1,MAPKAPK2,FGFR2,TWSG1,ACVRL1,PHLPP2,ITPR1,NFKBIA,GRIN2D,LTBP2,JAK3,ARHGEF9,ARHGEF4,RGMA,EHD1 |
| 7.749e-06 | -11.77 | regulation of protein localization | biological process | GO:0032880 | 906 | 133 | 16441 | 1675 |
EXPH5,TXN,LGR4,CACNA2D2,IL18,ITPR2,SYTL4,CCNB1,HDAC6,BARD1,ERP29,SLC8B1,CABP1,KCNS3,DLG1,MYRIP,RASGRP1,TRIM8,CELSR2,ACVR1C,NBPF3,EZR,PRKAR2B,SLC25A5,CDK1,SLC25A4,DNM1L,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,BMF,NFKBIE,TBC1D1,HLA-E,RAB23,NCKAP1,FBLN1,IL18R1,ANO1,LMNA,ITGA3,KCNN4,NEK2,SORL1,MDFIC,CACNA1D,WNT3A,MDFI,EPB41L5,MMD,TP53INP2,CDK5R1,STX3,GNAS,TMEM30A,ITPR1,CDCA5,NFKBIA,YOD1,TMEM173,LZTFL1,SORBS1,NF2,IQGAP1,THRA,TP53,ERBB2,CD274,BCL2L1,APC2,PRKACA,BCAP31,ARHGEF16,NOV,SP100,CDH1,DACT1,TWIST1,DAB2IP,MYT1,F2R,CHP1,SIRT1,ERLEC1,AKT1,PTGER4,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PPP2R5A,NRG1,EFNA5,TCAF1,PINK1,PSMD10,HMGN3,TGFBR1,SIX4,NEO1,WWP2,KIF5B,CARD8,CDK16,LLGL2,BMP7,FAM20B,UBE2J1,TMBIM6,MAPK11,SYK,HES1,RHOA,SYBU,PIK3R1,RGCC,LITAF,BORA,GPLD1,NUCB1,SWAP70,BANK1,SYT7,ARRB1,SPCS3,GPER1,FZD5,NDFIP1,PKIA |
| 7.807e-06 | -11.76 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | 527 | 84 | 17758 | 1761 |
LZTFL1,GRHL2,HOXB7,DNAJC3,PPFIBP2,TP53,KCTD12,CMTM6,DAPK2,NOV,CYP1A1,CTGF,SP100,METTL7A,LMO4,BCL6,IRF2,IFIT1,OAS3,RCAN3,LAMP3,SEMA3B,MX1,PPIF,GCA,TRIM8,KIFC2,CAPN6,USP18,SEPT6,ARFRP1,SHROOM3,PLK2,CORO1C,LRIG1,IRF7,HSPB1,LIFR,PARP12,TBC1D1,HLA-E,ARMC7,OSGIN2,INTS8,TRIB2,SEPP1,FAM21C,EFNB1,LGALS3BP,CXCL16,ALG13,FJX1,TRIM21,SGK1,RIMS2,MCCC2,PARP9,ARAP2,SHMT1,ERMAP,MMD,PRSS23,PLSCR1,CRB3,BCL9,ELK1,IFIT3,FNDC3A,STEAP1,CDK5R1,FAS,PRDX4,KLHL2,RND3,CSF1,ERAP1,DONSON,LTBP2,CMPK2,OSR1,IFIH1,JAK3,AHR,XDH |
| 7.847e-06 | -11.76 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 464 | 76 | 17758 | 1761 |
MTM1,LZTFL1,TTC39B,TSC22D3,SLC25A13,PKP2,KCTD12,FAM101B,CA8,CACNB4,FAM46C,CARD10,TMC1,SYTL2,DAPK2,RPS6KA2,CDH1,F2R,CPD,GCA,SAT1,SESN1,RNF19B,SP4,ATP13A2,SOCS3,PTPRJ,TLE1,RELL1,ARF6,NRGN,F2RL1,FBLIM1,RUNX2,EPS8,NUCB2,DHRS3,MERTK,AIP,FZD6,B4GALNT1,KCNN4,RANBP1,SORL1,SGK1,MDFIC,SGCB,MYO5A,PRSS23,PLSCR1,STAT4,PLAUR,TCF7,PDK3,YES1,KIF11,FOS,FRMD4B,SOX13,GALNT3,ARHGAP24,ENDOD1,PTPRF,NR1D2,SYT7,TMEM30A,CDCA5,ABCB1,SH3BGRL2,FHL1,LRRK1,GEM,ICOSLG,SERPINB1,AHR,RAB3IL1 |
| 7.957e-06 | -11.74 | response to external stimulus | biological process | GO:0009605 | 2118 | 274 | 16441 | 1675 |
HSPG2,DNAJC3,NRG2,PSME1,IL18,PLXNA1,CCNB1,CMTM6,CALM2,TYMP,CYP1A1,PSMD1,ELMO2,ZFP36,ALDH1A3,FOSB,CRY2,SEMA3G,PIK3CD,TIAM1,APOBEC3G,METAP2,ACVR1C,CASP9,SLC35C1,POR,ABR,PLCG1,LIMK1,NOD2,UNC5B,HSPB1,F2RL1,DDX58,SEMA6B,SCN5A,NUAK1,ITGA6,HLA-E,SOX9,SLC1A3,ATG4A,MECOM,CYR61,RPL39,FLRT3,FAM13B,OPN3,ALPK1,CACNA1D,NCAM1,NUP85,CALM1,ANO6,NPC2,EPHA1,GNA11,PSMA4,NFIB,RASA1,FAS,SEMA4D,MATN2,MDH1,NR4A2,ARPC2,IFIH1,TMEM173,SPRED1,NQO1,THRA,RPS6KA1,RALBP1,BCL2L1,CDS1,APOBEC3B,CCND1,NOV,DAB2IP,PDE4D,IFIT1,EPHB4,ACSL4,LRP11,RASGEF1A,DLG3,CDKN2D,ETV4,SEMA3B,ATG4D,MX1,DOCK4,COL6A2,RIPK2,APOBEC3D,PRKCQ,ATP1B1,RAB38,ALCAM,CMTM7,EPHA10,IRS2,JAK1,CDK19,SHROOM3,AXL,NRG1,DENND5B,SDC4,HABP4,HERC5,APOBEC3H,ETS1,GSTP1,FGF19,EFNB1,HLA-A,NEO1,CXCL16,FAM111A,GNB5,PTEN,CST3,IGFBP2,MAPK11,ERBB3,FARP2,RASGRF1,ARHGEF28,B3GNT2,PLSCR1,RAPGEF2,GRIN1,YES1,FOS,CNTNAP1,PITX2,TIMP3,FGFR2,NR4A3,RYK,ERAP1,GRIN2D,ITGAV,HMGA1,CMPK2,FZD5,ARSB,WDR45B,USF2,RGMA,MYL9,CASP3,EPHA4,LMCD1,NENF,SDC1,PDGFB,CACNB4,SPTB,TMC1,RPS6KA2,SHC3,NPNT,DPYSL2,DLG1,DUSP10,TRPC1,NTN4,MYH14,RASGRP1,ITCH,EZR,PRKRA,OPTN,DPYSL3,WIPI1,PIEZO1,MYL12B,RRAGD,PRKAA2,LGALS3,SERPINE2,RASA2,CALM3,CNTNAP2,PHLPP1,DHRS3,ANO1,IGF1R,COL6A1,AHCY,PIM1,WNT3A,SLC12A2,DPYSL5,RGMB,EIF2AK1,SCRIB,IFIT3,RANBP9,CDK5R1,MAPKAPK2,FECH,NFKBIA,NLRC5,PITPNA,PLD1,SHROOM2,JAK3,SEMA3A,KLF7,GAS2L1,IL15,PSME2,TP53,ERBB2,IL27RA,ARHGEF16,IER3,PDGFA,ARTN,PLCG2,SRR,OAS3,F2R,FRS3,SIRT1,AKT1,PTGER4,ERBB2IP,CD40,DAG1,MYL12A,SOCS3,ARHGAP35,ATP1A1,PTPRJ,ABHD12,IRF7,SPTBN5,EFNA5,ABCA1,CMTM4,ANXA3,COL9A3,CPEB4,ARHGEF11,CD63,DAP,PSMD10,COL4A5,NRP2,KIF5B,ADORA1,BMP7,TFAP2A,SYK,RHOA,PSMB4,IFITM3,PLAUR,NR4A1,PPARA,LITAF,BBS2,BCAR1,HLA-B,SCG2,CTSV,PGRMC1,ARRB1,L1CAM,PTGES |
| 8.272e-06 | -11.70 | VERHAAK_AML_WITH_NPM1_MUTATED_DN | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_DN | 239 | 46 | 17758 | 1761 |
SERPINE2,HSPG2,ATP9A,ITGA6,XYLT1,EPS8,CACNA2D2,GPSM2,DSE,TRIB2,DHRS3,TSPAN7,FZD6,MECOM,RPS6KA2,DPYSL2,LMO4,SORL1,MDFIC,TSPAN13,TACSTD2,MTMR11,NCAM1,SMAGP,MX1,PRODH,ARAP2,ALDH2,PTGER4,AK4,EZR,RUNX3,LHFPL2,OPTN,ENDOD1,BANK1,H1F0,ABCB1,SH3BP4,EGFL7,ADIPOR1,FHL1,TRAF5,F2RL1,HSPB1,RRAGD |
| 8.346e-06 | -11.69 | GSE7852_LN_VS_THYMUS_TREG_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_DN | 190 | 39 | 17758 | 1761 |
CMAS,LZTFL1,ENO2,LGALS3,CRYM,HEBP1,HAL,TDRKH,GPSM2,FAM101B,C11orf95,PARM1,CTSC,LMO4,TSPAN6,FUT8,PAPSS1,ATRNL1,DUSP10,NTN4,SEPHS1,PCGF5,IFITM3,EZR,PRICKLE1,TCF7,FAM133B,PRKAR2B,NUSAP1,PRKRA,ICMT,PTGFRN,TCEAL8,PTPRF,MAMDC4,PTER,FHL1,ACOT7,CYBRD1 |
| 8.346e-06 | -11.69 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | 190 | 39 | 17758 | 1761 |
TRIM2,AASS,ATP8A1,ERBB2,IL27RA,FTH1,SPTB,PPP2R3A,PARM1,CDS1,PLS3,APLP2,BTG3,RPS6KA2,RIMS3,KCNS3,LIMCH1,CITED2,TIPARP,S100A13,ELK3,CD55,NR3C1,SLC39A8,RAPGEF2,RAB38,BLVRA,ZFAND5,MAP3K6,CYB5A,PIAS3,ALDH3B1,ALDH5A1,NFKBIA,RHOBTB2,ARRB1,GEM,ITPKA,LTA4H |
| 8.419e-06 | -11.69 | cell-cell junction | cellular component | GO:0005911 | 377 | 65 | 17570 | 1756 |
ILDR1,SORBS1,KIAA1462,GRHL2,IQGAP1,PKP2,F11R,MPP5,CCND1,EPCAM,NOV,CDH1,DLG1,AKR1B1,CLDN4,CDH3,POF1B,EPB41L4B,SCN2A,TLN2,DLG3,TIAM1,SMAGP,CAMSAP3,AKT1,FZD4,PTPRU,ATP1B1,DAG1,PLCG1,PTPRJ,ATP1A1,SHROOM3,PTK7,DDX58,SCN5A,PACSIN2,FRMD4A,BVES,FRMD6,CALB2,TGFBR1,TEC,ADD3,TBCD,PANX2,IQGAP3,PIKFYVE,AMOTL2,PVRL4,RHOA,PCDH1,CRB3,RAPGEF2,PIK3R1,SCRIB,STEAP1,STX3,TJP3,PVRL2,COL13A1,RAP2C,FZD5,SHROOM2,OCLN |
| 8.429e-06 | -11.68 | BROWNE_HCMV_INFECTION_2HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_DN | 48 | 16 | 17758 | 1761 |
RAB3B,CENPA,PLAUR,ITGA6,KIF23,PHLDA1,DGKE,RAD23A,ITGA3,COL13A1,AXL,SGK1,CDKN1B,CENPE,UBE2C,ABCC1 |
| 8.458e-06 | -11.68 | GSE360_CTRL_VS_T_GONDII_DC_UP | MSigDB lists | GSE360_CTRL_VS_T_GONDII_DC_UP | 197 | 40 | 17758 | 1761 |
PINK1,ZCCHC24,INPP5D,ETV5,HEXB,KCTD12,TGOLN2,ITPR2,MGST2,CRABP2,TRIB2,VASH1,SRPX2,PDIA4,METTL7A,MEGF8,ATP5H,PLCG2,FABP6,KCNS3,BAX,SORL1,AHCY,PIKFYVE,S100A13,CORO2A,S100A4,IDH1,FUCA1,ALDH3B1,SCG2,RAB11FIP2,PRCP,SLC9A6,TCEAL4,PNPLA6,LTA4H,SEMA3A,NRGN,PTGES |
| 8.604e-06 | -11.66 | stomach-adenocarcinoma | COSMIC cancer mutations | stomach-adenocarcinoma | 4272 | 497 | 17775 | 1757 |
SUN1,ACACB,PPP4R4,ADD1,LGR4,TTC39B,AASS,SLC25A13,ATP8A1,TSC22D3,CACNA2D2,MMADHC,LYNX1,DPP8,BARD1,SLC20A1,LTBP3,NCS1,EPDR1,WEE1,PSMD1,MUC4,CTGF,ELMO2,ALDH1A3,IL31RA,KLF3,AOX1,STEAP2,KCNS3,PIK3CA,ATRNL1,SNX16,HYLS1,PIK3CD,RNF26,TIAM1,TIPARP,MGAT5,METAP2,SPEF2,LOC81691,SPATA18,PBK,TMEM151A,PRKAR2B,TNS1,COL12A1,ENPP1,PLCG1,DNM1L,PLK2,ATP7B,GNPTAB,LRIG1,NKD1,FAM114A1,PRDM5,ITPKA,UNC5B,TRAF5,GAB1,E2F8,LZTS1,DDX58,MRC2,FRMD4A,NFKBIE,FAM169A,GGA1,C6orf106,KIF23,SLC36A4,ISYNA1,GPSM2,HPCAL4,MESDC2,MECOM,ATG4A,DOPEY2,FRY,PIK3AP1,SNX18,VASN,FAM13B,RANBP1,RUNDC3B,DAPK1,PCYOX1,MAP3K9,SORL1,ALPK1,C8orf58,CACNA1D,PIKFYVE,ZMYM1,MYLIP,SYTL3,RIMS2,IGSF3,TRAK2,EPB41L5,FADS2,MMD,ZNF84,KIF20A,TBC1D8B,SALL4,STAT4,CALM1,AMER1,ANO6,NPHP3,SPTLC2,ANTXR1,PTPRF,DGKH,CACHD1,NCOA3,PLEKHH2,SLC4A4,SETD3,SLC4A3,CLMN,PCDH19,SFMBT1,CABIN1,CDK18,NR4A2,NDE1,MAP3K5,SERPINB1,IFIH1,NRBP1,XDH,MTM1,SPRED1,TCTN2,CEP70,TRIP10,NLRX1,BROX,IQGAP1,RGS20,PKP2,FTH1,NUF2,GRK6,MGST2,DDR1,MNS1,CYP39A1,ZFYVE9,APPBP2,APLP2,ST5,SCNN1A,CDH1,DACT1,XYLT2,RTKN2,ACSL4,EPHB4,MYT1,NR2C1,SCN3A,MYO5B,MX1,SEC23A,COG2,FZD4,CAPN6,PTPN9,SYNE2,SAT1,PANK1,UTRN,HTATIP2,SLC11A2,C15orf39,ITPR3,ALCAM,ATP10D,NIN,EPHA10,JAK1,PPP2R5A,SHROOM3,CDK19,AXL,TSPAN18,SIPA1L1,PNPLA6,NRG1,MLKL,HS3ST3B1,RGS14,COBL,NUDT6,PCOLCE,CKAP2,HAPLN3,OSGIN2,HERC5,ANO9,PKN1,DNAH3,SLC25A43,HOXB2,BEX2,SIX4,NEO1,WWP2,E2F7,ADD3,ITGB8,SLC27A6,PHF7,PTEN,CALD1,MGAT4A,FUT8,SGK3,ATP8B1,FAM102A,SLC44A2,IGFBP2,TAGLN2,ERBB3,SGCB,RASGRF1,TGIF1,ALDH2,ARAP2,ZC3H11A,RAPGEF2,MRS2,CXorf57,PARP4,DIAPH2,BLVRA,CDK5RAP1,CNTNAP1,PLOD2,ACVRL1,NR1D2,TBX18,DBI,ABCB1,ERAP1,CENPE,ETAA1,ITGAV,WDR62,ARSB,NCAPG2,SLC25A38,USF2,ESPL1,DCBLD1,ACOT7,DEF6,OCLN,TLL2,JARID2,EXPH5,UNKL,LTBP1,ILDR1,CASP3,BCAM,KIAA1462,GNPDA1,CNOT8,CPT2,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,TEX2,MGAT5B,ITPR2,HDAC6,SDC1,DNER,KREMEN1,TMC1,SPTB,ABCD4,SIPA1L2,LRRC6,NPNT,DPYSL2,IL6ST,SLC44A1,PHTF1,ANKFN1,MITF,DLG1,ANKRD12,AKR1B1,ANO4,SLC39A10,TLN2,DDX59,CCDC38,ZNF462,PLK1,MCTP1,CD55,CELSR2,STAU2,ITCH,CBX6,ANLN,IDH1,SESN1,LHFPL2,RHEB,EDNRA,TRIM9,PLEKHG6,MFAP3L,HS6ST1,PLCH1,HPSE,MAP2,MADD,RAB11FIP1,KLF11,EPB41L4A,CPPED1,STARD3NL,NR2C2,GRN,PRKAA2,CD99,RUNX2,ZCCHC24,RASA2,PYROXD2,CNTNAP2,SAMD9,IL18R1,TNS3,CA2,IGF1R,RINL,LIMCH1,HLA-C,RFX5,SLC12A2,MPHOSPH9,ALS2CL,CCDC88A,ABCC1,DPYSL5,CHSY3,CYP26B1,TESK1,CORO2A,MGAT4B,PDE5A,BTN3A2,EIF2AK1,SCRIB,NUBP1,MFSD7,RANBP9,PRX,GNAS,FECH,ONECUT1,UAP1,CSF1,MFSD2A,PHLPP2,SEMA3A,JAK3,COL16A1,SNX30,KLF7,LMO7,LZTFL1,SLC25A24,UPF3B,SPC25,TMX4,TP53,COL18A1,ERBB2,SLC7A2,SYTL2,CYP26A1,PDGFA,TTC21B,SS18,SLC25A48,WDR44,KIF14,FRYL,CDH3,GLB1L2,ESPN,EPB41L4B,NOTCH3,LMAN1,SCN2A,SCYL3,GM2A,CTH,SUSD3,CPD,SIRT1,MAP3K3,ERLEC1,AKT1,ERBB2IP,DUOX1,IDE,PTPRJ,RBL1,PTK7,STK38,EFNA5,NDST3,MAN2B2,PINK1,SORT1,PACSIN2,GOLIM4,ARHGEF11,FRMD6,POC1B,LRP4,GNE,BLVRB,CDCA8,TGFBR1,COL4A5,HMGN3,GDF15,NOTUM,INTS8,SBF1,FAM167A,VPS26A,PPP2R3A,NRP2,SH2D4A,DNAJB9,ZDHHC21,CD109,IL17RB,FOXP2,LLGL2,RRBP1,UBE2J1,KIAA0319,ARVCF,BUB1,IQGAP3,MYO5A,TLE6,ATP2B1,DLGAP1,HMMR,SYPL1,SUN2,MOSPD2,PSMB4,GCLC,ASPM,RC3H2,MBNL3,PRICKLE1,GGH,COL7A1,TXNDC11,BBS2,BCAR1,KLHL2,BANK1,FAT4,C2orf70,DHRS2,CLIP4,FAM117A,PLOD3,TBC1D4,HIPK3,ARHGEF9,L1CAM,ARHGEF4,GOLGB1,DIS3L |
| 8.622e-06 | -11.66 | programmed cell death | biological process | GO:0012501 | 1074 | 153 | 16441 | 1675 |
LAMP1,CASP3,ADD1,RET,PSME1,SH3KBP1,DAPK2,RPS6KA2,PSMD1,CTGF,ELMO2,SIVA1,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,STK17B,CDK1,POR,ABR,SLC25A4,DNM1L,MADD,KLF11,UNC5B,ARF6,TRAF5,FGD1,BMF,NCKAP1,PHLPP1,ADAMTSL4,TNFRSF19,LMNA,MECOM,TFAP4,CYR61,MAP3K9,DAPK1,SELK,TNFRSF12A,CD70,MYDGF,PIM1,WNT3A,PRODH,ERO1A,SCRIB,PSMA4,G2E3,FAS,STK17A,H1F0,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,TMEM173,XDH,PSME2,RPS6KA1,INPP5D,TP53,BCL2L1,AIFM2,PHLDA1,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,CDKN1B,DAB2IP,SCN2A,EGLN3,F2R,CDKN2D,ATG4D,SIRT1,PPIF,MX1,EVA1A,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,EFNA5,MLKL,AIFM3,ZMAT1,GCLM,SORT1,NKX3-1,ARHGEF3,ARHGEF11,CKAP2,DAP,RASSF7,PSMD10,TGFBR1,PKN1,BEX2,SGPL1,TOP2A,CARD8,ADORA1,CTSC,PTEN,CST3,DRAM1,BAX,SGK1,ADAM15,TMBIM6,PLEKHF1,BUB1,ERBB3,FAIM,RHOA,PSMB4,PLSCR1,GCLC,PLAUR,PIK3R1,LITAF,CTSL,FGFR2,TRIM69,CTSV,ARRB1,UACA,GPER1,ITGAV,FZD5,ARHGEF9,AHR,HIPK3,ESPL1,MELK,OCLN,ARHGEF4 |
| 8.637e-06 | -11.66 | cellular protein metabolic process | biological process | GO:0044267 | 3550 | 432 | 16441 | 1675 |
SSH1,ADD1,HSPG2,MRPS15,DNAJC3,HEXB,RET,FBXO2,NRG2,PSME1,IL18,NANS,MORF4L2,CAMK1D,CCNB1,PJA2,BARD1,GRM5,CALM2,DAPK2,WEE1,PSMD1,MUC4,UBE2T,IL31RA,PALD1,PIK3CA,FUT1,CRY2,PIK3CD,TINAGL1,MARCH2,TIPARP,MGAT5,METAP2,FBXL16,TNIP1,SPATA18,ACVR1C,PBK,MTRF1L,LOXL2,GALNT7,ICMT,CCNF,MCFD2,RNF19B,POR,ARF4,PIAS3,PLK2,LIMK1,GNPTAB,PRDM5,NOD2,HDAC1,EIF4EBP2,MRPS28,ITPKA,TRAF5,GAB1,CDK17,MRPL44,GGA1,NUAK1,SOX9,HERC6,MERTK,TNFRSF19,BMP2K,LMNA,RABGGTA,ATG4A,MARCH8,ZNRF2,RPL39,PPP4R1,NEK2,TPST1,DAPK1,PCYOX1,ADCK2,MAP3K9,PRKG1,OPN3,ALPK1,MYDGF,NCAM1,MAST4,MYLIP,NUP85,PPP6R1,SOCS5,TRAK2,GFPT1,PMPCB,DDB2,B3GNT7,MMD,STAT4,CALM1,ERO1A,EPHA1,ELK1,TP53INP2,JADE2,PSMA4,RASA1,STK17A,MMP15,PTPRF,NCOA3,PRKAG2,TIMM8A,PELI2,SETD3,CSNK1G1,AGBL5,AURKA,STK39,CDK18,MAP3K5,CFAP20,IFIH1,NRBP1,NUP58,RUSC1,EGLN1,SPRED1,MTM1,DLGAP5,GALNT12,INPP5D,RPS6KA1,PTTG1,TESK2,RNF182,GRK6,MVB12B,PRKACA,DDR1,CCND1,MUC16,RNF220,SP100,DOK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,LGMN,ATG4D,SEC23A,SSH3,SEC61B,RIPK2,PTPN9,PRKCQ,PKMYT1,ASB13,XRCC6BP1,EPHA10,IRS2,JAK1,DDOST,CDK19,STK26,WFS1,AXL,TRIOBP,TRABD2A,NRG1,MLKL,MAPK12,IGFBP6,DCAF7,PDIA3,HERC5,CTSZ,FBXO6,PKN1,FGF19,WWP2,DTX3L,FUT2,RNF128,CTSC,ARSG,PTEN,ALG13,MGAT4A,CST3,FUT8,SGK3,WWP1,IGFBP2,MAPK11,ERBB3,TRIM62,NCOA2,CRTAP,RASGRF1,B3GNT2,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,NEURL1B,FOS,ARSK,GALNT3,RPL12,PLOD2,FGFR2,ACVRL1,DBI,PPM1H,RYK,GRIN2D,ITGAV,LRRK1,ARSB,WDR45B,CPEB2,MELK,UNKL,TRIM2,PPM1J,CAMKK1,CUL4B,EPHA4,LMCD1,DNAJB11,VARS2,MGAT5B,HDAC6,PDGFB,DNER,TRIM68,SPTB,RPS6KA2,SHC3,MKRN3,PASK,DLG1,DUSP10,PTPRE,TRAM1,RASGRP1,PLK1,TRIM8,ITCH,USP18,ROR1,PRKRA,MRPS36,CDK1,ADRBK2,STK17B,KDM4D,TRIM9,MAN2A2,MSL1,UEVLD,WIPI1,P4HA2,DOLPP1,CAB39,CPPED1,PCSK5,PRKAA2,LMTK3,DNAJB2,RASA2,UBASH3B,ASB9,CALM3,ADCK5,RAB6A,TEC,B4GALT4,PHLPP1,ADAMTSL4,B4GALNT1,OTUD1,B3GALNT1,UBE2Q2,IGF1R,TBCD,EXOC8,MDFIC,PIM1,ZRANB1,GAD1,CKAP4,MDFI,MRPS33,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,G2E3,CDK5R1,MAPKAPK2,UAP1,PLPP3,PHLPP2,KBTBD2,P4HA3,ZDHHC7,ALPK3,YOD1,CTSA,JAK3,RNF146,USP43,LMO7,IL15,P3H2,PSME2,CTDSPL,HDAC11,PDIA5,ERBB2,KBTBD11,RAD23A,PDGFA,SETDB2,ZDHHC12,KIF14,PLK4,ZDHHC23,RPN2,NOTCH3,LMAN1,EGLN3,F2R,PDIA6,CTDSP2,SCYL3,FRS3,CTH,SEPHS1,MAP3K3,PPIF,SIRT1,ERLEC1,AKT1,PTPRU,CDC20,PTGER4,DUSP4,MAP3K6,SOCS3,JADE1,DNAJC10,IDE,ATP1A1,PTPRJ,STK38,PTK7,PEX2,SPTBN5,ST3GAL1,ABCA1,MAN2B2,CMAS,PINK1,CPEB4,KLHL13,CIT,GNE,PSMD10,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,DNAJB9,PPP2R3A,HDAC9,ZDHHC21,KIF5B,ADRBK1,CDK16,A4GALT,RRBP1,UBE2J1,SGK1,TRIM21,BUB1,IQGAP3,SYK,MYO5A,GCNT1,B3GALT6,RAB3B,PSMB4,PLAUR,AMFR,RC3H2,RUNX3,COL7A1,PELI3,MAPK8IP1,PRDX4,KLHL2,FUCA1,CTSL,SERPINA1,TRIM69,SCG2,CTSV,DTX4,OTUB2,ARRB1,SPCS3,PLOD3,CEP41,NDFIP1,UBE2C,HIPK3 |
| 8.859e-06 | -11.63 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 170 | 36 | 17758 | 1761 |
GCLM,TXN,GNPDA1,OSGIN2,IL18,CD274,SCML1,IER3,E2F7,SGK1,SELK,PIM1,EGLN3,SPRY2,OSGIN1,WBP5,CKS2,HES1,B3GNT2,RIPK2,NR4A1,RAPGEF2,PLAUR,COQ10B,PTGER4,SAV1,STX3,SOCS3,SLCO4A1,ETS2,CSF1,NFKBIZ,NR4A2,PLD1,GLA,GEM |
| 8.902e-06 | -11.63 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1210 | 165 | 17775 | 1757 |
LTBP1,GAA,CRYM,CAMKK1,EPHA4,RET,DHX8,TEX2,CAMK1D,SLC20A1,DNER,TMC1,GRM5,PLS3,CDKN2C,NKAIN3,DAPK2,WEE1,RPS6KA2,MUC4,SHC3,ANKFN1,IL31RA,PIK3CA,ATRNL1,NTN4,CRY2,SLC39A10,PLK1,MCTP1,ACVR1C,PBK,ROR1,LDB2,IDH1,ADRBK2,STK17B,KCNK1,PLK2,LIMK1,TRAF3IP1,GAB1,PRKAA2,CDK17,FRMD4A,ADCK5,CNTNAP2,SAMD9,MERTK,BMP2K,MECOM,ATG4A,CA2,IGF1R,PIK3AP1,GATA2,BDH1,NEK2,DAPK1,PRKG1,MAP3K9,ADCK2,CADPS2,ALPK1,PIM1,CACNA1D,KDELR1,ADCK3,TESK1,STAT4,STRADB,VEZT,EIF2AK1,PDK3,PDIK1L,C3orf58,NFIB,STK17A,GNAS,MAPKAPK2,CACHD1,ALPK3,AURKA,CABIN1,CDK18,LTBP2,MAP3K5,JAK3,NRBP1,NCKAP5,RPS6KA1,TP53,TESK2,ERBB2,NUF2,GRK6,SLC7A2,PRKACA,DDR1,ZNF385B,ST5,CDH1,PLK4,CDKN1B,EPHB4,LRP11,LGMN,SCYL3,CPD,MAP3K3,RIPK2,AKT1,SYNE2,PRKCQ,PKMYT1,MAP3K6,EPHA10,IDE,POPDC3,JAK1,BFSP1,CDK19,AXL,STK38,PTK7,EFNA5,MLKL,MAPK12,PINK1,PBX3,TGFBR1,COL4A5,PKN1,TRIB2,ADRBK1,PTEN,CDK16,ANKS1B,SGK3,PLEKHF1,SGK1,MAPK11,BUB1,ERBB3,SYK,MYO5A,PVRL4,PDGFC,FBLN5,RHOA,LONRF3,ASPM,CXorf57,DIAPH2,LRRC1,YES1,MAMDC4,FGFR2,SYT7,ACVRL1,GRAMD1C,CENPE,OSR1,HIPK3,MELK |
| 8.902e-06 | -11.63 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1210 | 165 | 17775 | 1757 |
LTBP1,GAA,CRYM,CAMKK1,EPHA4,RET,DHX8,TEX2,CAMK1D,SLC20A1,DNER,TMC1,GRM5,PLS3,CDKN2C,NKAIN3,DAPK2,WEE1,RPS6KA2,MUC4,SHC3,ANKFN1,IL31RA,PIK3CA,ATRNL1,NTN4,CRY2,SLC39A10,PLK1,MCTP1,ACVR1C,PBK,ROR1,LDB2,IDH1,ADRBK2,STK17B,KCNK1,PLK2,LIMK1,TRAF3IP1,GAB1,PRKAA2,CDK17,FRMD4A,ADCK5,CNTNAP2,SAMD9,MERTK,BMP2K,MECOM,ATG4A,CA2,IGF1R,PIK3AP1,GATA2,BDH1,NEK2,DAPK1,PRKG1,MAP3K9,ADCK2,CADPS2,ALPK1,PIM1,CACNA1D,KDELR1,ADCK3,TESK1,STAT4,STRADB,VEZT,EIF2AK1,PDK3,PDIK1L,C3orf58,NFIB,STK17A,GNAS,MAPKAPK2,CACHD1,ALPK3,AURKA,CABIN1,CDK18,LTBP2,MAP3K5,JAK3,NRBP1,NCKAP5,RPS6KA1,TP53,TESK2,ERBB2,NUF2,GRK6,SLC7A2,PRKACA,DDR1,ZNF385B,ST5,CDH1,PLK4,CDKN1B,EPHB4,LRP11,LGMN,SCYL3,CPD,MAP3K3,RIPK2,AKT1,SYNE2,PRKCQ,PKMYT1,MAP3K6,EPHA10,IDE,POPDC3,JAK1,BFSP1,CDK19,AXL,STK38,PTK7,EFNA5,MLKL,MAPK12,PINK1,PBX3,TGFBR1,COL4A5,PKN1,TRIB2,ADRBK1,PTEN,CDK16,ANKS1B,SGK3,PLEKHF1,SGK1,MAPK11,BUB1,ERBB3,SYK,MYO5A,PVRL4,PDGFC,FBLN5,RHOA,LONRF3,ASPM,CXorf57,DIAPH2,LRRC1,YES1,MAMDC4,FGFR2,SYT7,ACVRL1,GRAMD1C,CENPE,OSR1,HIPK3,MELK |
| 8.940e-06 | -11.63 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2074 | 262 | 17775 | 1757 |
RET,NRG2,CARD10,GRM5,WEE1,CYP1A1,IQCE,FOSB,PIK3CA,PIK3CD,TIAM1,TIPARP,NWD1,SPEF2,ACVR1C,CASP9,PRKAR2B,SAV1,PPP1R14C,CCNF,SLC25A5,COL12A1,PIAS3,PLCG1,HDAC1,TRAF5,F2RL1,HSPB1,GAB1,HOXC13,NFKBIE,ITGA6,HLA-E,RAB23,MERTK,PSIP1,MECOM,ELF3,ZNRF2,AIM1,FAM13B,NEK2,RUNDC3B,PIKFYVE,RIMS2,SOCS5,DDB2,STAT4,AMER1,ANO6,ELK1,RASA1,FAS,PTPRF,CACHD1,PRKAG2,ETS2,ITPR1,FGD6,AURKA,NDE1,MAP3K5,PLA2G4A,SPRED1,REPS2,DLGAP5,IQGAP1,RALBP1,RNF182,BCL2L1,PRKACA,DDR1,REPS1,CCND1,MUC16,CDH1,DOK4,CDKN1B,EPHB4,ETV4,COL6A2,FZD4,SEPT6,UTRN,PRKCQ,PKMYT1,ITPR3,SP4,FZD7,NIN,EPHA10,IRS2,PPP2R5A,JAK1,AXL,NRG1,MAPK12,TTC8,IGFBP6,CKAP2,PDIA3,HERC5,PKN1,DNAH3,ETS1,FGF19,SIX4,TMCC3,PDIA4,WWP2,DIRAS3,DTX3L,PTEN,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERBB3,SPRY2,TPCN1,NCOA2,PARP9,ACBD5,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,FURIN,UBE2A,FOS,CNTNAP1,PLOD2,FGFR2,PPM1H,GRIN2D,ETAA1,FZD5,EXPH5,CASP3,PPM1J,EPHA4,F11R,DNER,PDGFB,KREMEN1,ZFYVE16,RPS6KA2,CNTRL,MKRN3,MITF,ANKRD12,POF1B,DUSP10,TLN2,NEB,NLRP4,PLK1,CELSR2,USP18,ITCH,CR2,ROR1,ADRBK2,RHEB,EDNRA,PLCH1,NEIL1,GPRC5B,HOXA9,MADD,PIK3C2B,EPB41L4A,PRKAA2,LASP1,PARP12,RASA2,ETV5,ABCG2,IL18R1,OTUD1,IGF1R,PIM1,ZRANB1,ELK3,PDE5A,IFIT3,STEAP1,G2E3,GLCE,MAPKAPK2,GNAS,NFKBIA,EGFL7,YOD1,PLD1,JAK3,SEMA3A,RARG,USP43,LMO7,UGP2,NF2,TP53,ERBB2,MRAS,STIL,PDGFA,SS18,FRYL,PLCG2,BCL6,CDH3,TWIST1,NOTCH3,DVL2,MAP3K3,AKT1,PTPRU,PTGER4,GLO1,DUSP4,CD40,FANCE,CASP4,MAP3K6,SOCS3,RBL1,STK38,PTK7,LIFR,ABCA1,TM2D2,FRMD6,TGFBR1,FZD6,PPP2R3A,SLC9A2,KIF5B,MYCL,SGK1,BUB1,SYK,RBMS2,HES1,PHF20L1,RHOA,AMFR,RC3H2,OGDHL,MAML2,BCAR1,DGKE,MAPK8IP1,RND3,RAP2C,DTX4,ARRB1,OTUB2,GEM |
| 8.940e-06 | -11.63 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2074 | 262 | 17775 | 1757 |
RET,NRG2,CARD10,GRM5,WEE1,CYP1A1,IQCE,FOSB,PIK3CA,PIK3CD,TIAM1,TIPARP,NWD1,SPEF2,ACVR1C,CASP9,PRKAR2B,SAV1,PPP1R14C,CCNF,SLC25A5,COL12A1,PIAS3,PLCG1,HDAC1,TRAF5,F2RL1,HSPB1,GAB1,HOXC13,NFKBIE,ITGA6,HLA-E,RAB23,MERTK,PSIP1,MECOM,ELF3,ZNRF2,AIM1,FAM13B,NEK2,RUNDC3B,PIKFYVE,RIMS2,SOCS5,DDB2,STAT4,AMER1,ANO6,ELK1,RASA1,FAS,PTPRF,CACHD1,PRKAG2,ETS2,ITPR1,FGD6,AURKA,NDE1,MAP3K5,PLA2G4A,SPRED1,REPS2,DLGAP5,IQGAP1,RALBP1,RNF182,BCL2L1,PRKACA,DDR1,REPS1,CCND1,MUC16,CDH1,DOK4,CDKN1B,EPHB4,ETV4,COL6A2,FZD4,SEPT6,UTRN,PRKCQ,PKMYT1,ITPR3,SP4,FZD7,NIN,EPHA10,IRS2,PPP2R5A,JAK1,AXL,NRG1,MAPK12,TTC8,IGFBP6,CKAP2,PDIA3,HERC5,PKN1,DNAH3,ETS1,FGF19,SIX4,TMCC3,PDIA4,WWP2,DIRAS3,DTX3L,PTEN,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERBB3,SPRY2,TPCN1,NCOA2,PARP9,ACBD5,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,FURIN,UBE2A,FOS,CNTNAP1,PLOD2,FGFR2,PPM1H,GRIN2D,ETAA1,FZD5,EXPH5,CASP3,PPM1J,EPHA4,F11R,DNER,PDGFB,KREMEN1,ZFYVE16,RPS6KA2,CNTRL,MKRN3,MITF,ANKRD12,POF1B,DUSP10,TLN2,NEB,NLRP4,PLK1,CELSR2,USP18,ITCH,CR2,ROR1,ADRBK2,RHEB,EDNRA,PLCH1,NEIL1,GPRC5B,HOXA9,MADD,PIK3C2B,EPB41L4A,PRKAA2,LASP1,PARP12,RASA2,ETV5,ABCG2,IL18R1,OTUD1,IGF1R,PIM1,ZRANB1,ELK3,PDE5A,IFIT3,STEAP1,G2E3,GLCE,MAPKAPK2,GNAS,NFKBIA,EGFL7,YOD1,PLD1,JAK3,SEMA3A,RARG,USP43,LMO7,UGP2,NF2,TP53,ERBB2,MRAS,STIL,PDGFA,SS18,FRYL,PLCG2,BCL6,CDH3,TWIST1,NOTCH3,DVL2,MAP3K3,AKT1,PTPRU,PTGER4,GLO1,DUSP4,CD40,FANCE,CASP4,MAP3K6,SOCS3,RBL1,STK38,PTK7,LIFR,ABCA1,TM2D2,FRMD6,TGFBR1,FZD6,PPP2R3A,SLC9A2,KIF5B,MYCL,SGK1,BUB1,SYK,RBMS2,HES1,PHF20L1,RHOA,AMFR,RC3H2,OGDHL,MAML2,BCAR1,DGKE,MAPK8IP1,RND3,RAP2C,DTX4,ARRB1,OTUB2,GEM |
| 9.102e-06 | -11.61 | seminoma | COSMIC cancer mutations | seminoma | 726 | 108 | 17775 | 1757 |
LTBP1,TRIP10,TMEM41B,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,SP100,PIK3CA,PLK4,EPHB4,NEB,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,PRKAR2B,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,ABR,EPHA10,PLCG1,DUOX1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,BMP1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,DSE,MERTK,BMP2K,SNTA1,TMEM87B,IGF1R,ADRBK1,CDK16,PTEN,LLGL2,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,CD9,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MYLIP,SYK,MYO5A,ABCC1,ADCK3,TESK1,ASPM,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,RANBP9,STK17A,MAPKAPK2,FAT4,ACVRL1,FGFR2,PRCP,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 9.103e-06 | -11.61 | regulation of MAPK cascade | biological process | GO:0043408 | 778 | 117 | 16441 | 1675 |
SPRED1,AVPI1,NF2,FOXM1,PSME2,EPHA4,NRG2,ERBB2,NDRG2,PSME1,NENF,PDGFB,ERP29,SPTB,GRM5,CALM2,PDGFA,ST5,PSMD1,CTGF,NPNT,SHC3,DACT1,RGS3,DLG1,DUSP10,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,MAP3K3,TIMP2,RIPK2,TNIP1,AKT1,FZD4,ITCH,PBK,EZR,CD40,DUSP4,CDK1,MAP3K6,DAG1,FZD7,IRS2,PLCG1,PTPRJ,JAK1,ANKRD6,STK38,MADD,NOD2,PRKCDBP,SPTBN5,NRG1,RGS14,F2RL1,GAB1,PINK1,RASA2,CALM3,PSMD10,TGFBR1,GDF15,PKN1,TRIB2,PHLPP1,GSTP1,FBLN1,FGF19,MECOM,ADORA1,IGF1R,CYR61,PTEN,BMP7,MAP3K9,SORL1,MAPK11,MDFIC,MYDGF,ERBB3,NCAM1,IQGAP3,SYK,SPRY2,MDFI,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,STRADB,PDE5A,PSMA4,RANBP9,MAPK8IP1,RASA1,FAS,MAPKAPK2,BANK1,FGFR2,PELI2,RYK,FAM83D,ARRB1,GRIN2D,GPER1,GDF11,FZD5,MAP3K5,JAK3,HIPK3,XDH |
| 9.120e-06 | -11.61 | organ morphogenesis | biological process | GO:0009887 | 876 | 129 | 16441 | 1675 |
EMX1,GAA,HSPG2,LGR4,PLXNA1,FAM101B,SDC1,CTGF,STIM1,NPNT,IMPAD1,ALDH1A3,DLG1,TACSTD2,TIPARP,SP5,THRB,SPEF2,EZR,TFAP2C,SAV1,PRKRA,ZFAND5,ABR,NKD1,LRIG1,BMP1,HDAC1,HOXC13,CAPN1,FGD1,SCN5A,RUNX2,ITGA6,SOX9,RAB23,NCKAP1,DHRS3,ELF3,CA2,IGF1R,CYR61,GATA2,MEGF8,FRAS1,BHLHE41,WNT3A,SLC12A2,ETV7,MDFI,CYP26B1,SCRIB,NPHP3,NFIB,BCAR3,GNAS,NCOA3,COL13A1,CSF1,GDF11,SEMA3A,SHROOM2,RARG,EGLN1,ADAMTS16,HOXB7,GRHL2,NF2,THRA,RPS6KA1,COL18A1,PKP2,ERBB2,OSR2,STIL,PDGFA,SETDB2,CNNM4,TWIST1,EPHB4,ETV4,DVL2,DAG1,PTK7,PNPLA6,TLE1,NRG1,CTHRC1,NKX3-1,LRP4,CTSZ,TGFBR1,AES,HOXB2,FZD6,PPP2R3A,SIX4,SGPL1,CTNNBIP1,PTEN,BMP7,FJX1,TFAP2A,BAX,ADAM15,CITED2,SYK,SPRY2,MYO5A,GCNT1,PDGFC,HES1,FMN1,PPARA,BBS2,FOXL1,PITX2,FAT4,FGFR2,TWSG1,TBX18,NR4A3,FHL1,HOXB13,SOX8,FZD5,OSR1,PLOD3,ZMIZ1 |
| 9.123e-06 | -11.60 | regulation of immune system process | biological process | GO:0002682 | 1509 | 204 | 16441 | 1675 |
LAMP1,CASP3,LGR4,TSC22D3,LMCD1,TAP1,NRG2,PSME1,IL18,ITPR2,CAMK1D,CACNB4,PDGFB,SPTB,CALM2,DAPK2,PSMD1,AP1M2,RPS6KA2,SHC3,ELMO2,IL6ST,TSPAN6,IL31RA,MITF,PIK3CA,DLG1,DUSP10,PIK3CD,SCARA3,SLC39A10,PTPRE,APOBEC3G,SMAGP,RASGRP1,CD55,TNIP1,ITCH,USP18,CASP9,CR2,SLC35C1,EZR,AGO4,ABR,PLCG1,GPRC5B,LIMK1,HOXA9,TRAF3IP1,NOD2,F2RL1,GAB1,DDX58,LGALS3,THEMIS2,HLA-E,UBASH3B,RASA2,HLA-F,SOX9,CALM3,TEC,NCKAP1,SLC1A3,PHLPP1,MERTK,CA2,PIK3AP1,GATA2,KCNN4,FAM13B,ALPK1,HLA-C,C10orf54,NCAM1,WNT3A,SOCS5,KLK5,MICB,CALM1,ANO6,PDE5A,ELK1,PSMA4,RASA1,FAS,SOX13,GNAS,MAPKAPK2,PVRL2,PELI2,PHLPP2,CSF1,NFKBIA,ITPR1,NLRC5,MDH1,FAM213A,KLK7,ARPC2,IFIH1,JAK3,RARG,TMEM173,GAS2L1,SPRED1,NLRX1,IL15,INPP5D,RPS6KA1,PSME2,ERBB2,IL27RA,SLC7A2,CD274,PRKACA,TNFSF9,PDGFA,NOV,CDH1,PLCG2,BCL6,CDKN1B,DAB2IP,PDE4D,IFIT1,TMEM64,RASGEF1A,LGMN,FRS3,SIRT1,RIPK2,AKT1,PTGER4,PRKCQ,ATP1B1,ERBB2IP,ITPR3,DUSP4,CD40,SOCS3,IRS2,PTPRJ,JAK1,AXL,INPP4B,NRG1,IRF7,SPTBN5,TNRC6C,BTN3A1,HERC5,PSMD10,SELL,PKN1,ETS1,EFNB1,FGF19,HLA-A,CTNNBIP1,ADORA1,PTEN,BAX,TMBIM6,IGFBP2,MAPK11,ERBB3,CNPY3,SYK,PARP9,RASGRF1,HES1,RHOA,PLSCR1,PSMB4,MPP1,RAPGEF2,NR4A1,PIK3R1,GRIN1,RGCC,YES1,FOS,BCAR1,GPLD1,CD83,CTSL,HLA-B,BANK1,SWAP70,FGFR2,NMI,NR4A3,ERAP1,PPP2R3C,GRIN2D,GPER1,ICOSLG,FZD5,NDFIP1,AHR,CD33,TMEM131 |
| 9.185e-06 | -11.60 | antigen processing and presentation of endogenous antigen | biological process | GO:0019883 | 13 | 8 | 16441 | 1675 |
HLA-B,TAPBP,HLA-E,TAP1,ERAP1,HLA-C,HLA-A,ERAP2 |
| 9.209e-06 | -11.60 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1176 | 161 | 17775 | 1757 |
HSPG2,SLC25A13,RET,SPTB,SLC9A7,CALM2,TYMP,WEE1,SIPA1L2,RPS6KA2,PQLC2,MUC4,PAPSS1,DLG1,PIK3CA,ANKRD12,SEMA3G,ACOX2,PIK3CD,MYBL1,ERAP2,ZNF462,SMARCA2,TNIP1,SERTAD4,PBK,PRKRA,IDH1,MAP2,PLK2,ATP7B,MADD,PRKCDBP,PIK3C2B,TANC2,HOXC13,MRC2,RUNX2,CDK17,ZNF395,CHCHD7,IGF1R,FRAS1,DAPK1,PRKG1,OPN3,MAP3K9,PIM1,CACNA1D,PIKFYVE,ALDH3A2,MPHOSPH9,ADCK3,PIP4K2C,SPATA13,BTN3A2,EIF2AK1,PDK3,NFIB,MAPKAPK2,SEMA4D,DCK,FGD6,AURKA,MAP3K5,JAK3,TOB1,ADAMTS16,MFSD3,SLC25A24,TRIP10,CAST,RPS6KA1,THRA,TP53,ERBB2,GRK6,PRKACA,DDR1,APPBP2,MUC16,SP100,LHX6,BRI3,EPHB4,DLG3,LRP11,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,AKT1,COG2,CAPN6,SYNE2,UTRN,ERBB2IP,ATP1B1,MAP3K6,NFIX,DUOX1,PTPRJ,JAK1,CDK19,AXL,STK38,PTK7,OVOL1,IRF7,KLF5,AIFM3,LIFR,ABCA1,MAPK12,PINK1,TNRC6C,CENPI,GNE,FAM134A,NOTUM,SEPP1,TMEM63A,SLC25A36,NEO1,DIRAS3,FOXP2,ITGB8,PTEN,CDK16,MGAT4A,TFAP2A,SGK1,MAPK11,IGFBP2,ERBB3,SYK,SUN2,B3GNT2,ARAP2,ARHGEF28,ELOVL3,PIK3R1,ZKSCAN2,AK4,MAML2,COL7A1,LRRC1,YES1,RNPEP,MAPK8IP1,FAT4,FGFR2,CENPE,ZMIZ1,OSR1,TBC1D4,ESPL1,L1CAM,MELK |
| 9.295e-06 | -11.59 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2309 | 295 | 16441 | 1675 |
ACACB,TXN,PPP4R4,LGR4,TSC22D3,DNAJC3,PSME1,MORF4L2,CCNB1,BARD1,CALM2,CDKN2C,PSMD1,ZFP36,RGS3,FOSB,IRF2,CRY2,ZBTB18,APOBEC3G,SMARCA2,TNIP1,PBK,CDA,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,POR,AHRR,PIAS3,ENPP1,LIMK1,TRAF3IP1,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,E2F8,LZTS1,CDKN1C,SOX9,RAB23,MECOM,ELF3,TFAP4,PAIP2B,BHLHE41,DAPK1,SORL1,SOCS5,SALL4,CALM1,EPHA1,PSMA4,NFIB,PLIN5,FAS,AP1AR,PRKAG2,ETS2,SEMA4D,SFMBT1,NR4A2,STK39,PER3,SERPINB1,XDH,EGLN1,SPRED1,S100A11,THRA,INPP5D,RPS6KA1,IQGAP1,CAST,PTTG1,BCL2L1,CCND1,APLP2,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,CDKN2D,NR2C1,CAMSAP3,APOBEC3D,DRAP1,RAD17,PKMYT1,H2AFV,SNX12,NFIX,IRS2,PPP2R5A,WFS1,CORO1C,SLC27A1,KLF5,NRG1,RGS14,CBX7,TNRC6C,NKX3-1,DEPDC1,APOBEC3H,PKN1,GSTP1,TIPRL,FGF19,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,RNF128,PTEN,CST3,BAX,ATP8B1,TMBIM6,WWP1,CITED2,CNOT6L,SPRY2,TRIM62,NCOA2,CRTAP,TGIF1,RAPGEF2,FURIN,GPLD1,CDK5RAP1,PITX2,TIMP3,FGFR2,NR1D2,ACVRL1,TBX18,NR4A3,ITGAV,GPER1,HMGA1,LRRK1,OSR1,CPEB2,JARID2,SIGIRR,CASP3,CRYM,LMCD1,NDRG2,HDAC6,PDGFB,SIVA1,PASK,MITF,DLG1,DUSP10,CYP1B1,PLK1,THRB,CD55,KCNIP3,TRIM8,ITCH,CBX6,EZR,OPTN,EDNRA,NEIL1,KLF12,PRKCDBP,KLF11,GLA,LMTK3,RUNX2,SERPINE2,UBASH3B,DNAJB2,PDCL,CALM3,HES2,FBLN1,IGF1R,GATA2,MDFIC,PIM1,RFX5,ETV7,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,CDK5R1,NUDT16,PLPP3,NFKBIA,NLRC5,JAK3,IFI6,RARG,TOB1,NF2,FOXM1,PSME2,CTDSPL,TP53,OSR2,SYTL2,IER3,PDGFA,SVBP,SETDB2,BCL6,TWIST1,NOTCH3,CTDSP2,CHP1,PPIF,SIRT1,TIMP2,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,SOCS3,ARHGAP35,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,STK38,PEX2,OVOL1,PTBP3,TLE1,IRF7,ARFGEF3,GLIS3,PINK1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,SH2D4A,FZD6,HDAC9,CD109,IRF2BPL,FOXP2,TAF1B,BMP7,TFAP2A,TRIM21,BUB1,NFE2L3,HES1,RHOA,PSMB4,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,COL7A1,RUNX3,LEPR,MAPK8IP1,SWAP70,BANK1,SERPINA1,NMI,SPINT2,ARRB1,SOX8,UBE2C,NDFIP1,HIPK3,AHR,PKIA,ZBTB33 |
| 9.361e-06 | -11.58 | intracellular organelle part | cellular component | GO:0044446 | 7812 | 866 | 17570 | 1756 |
ACACB,ADD1,IL15RA,MRPS15,AASS,SLC25A13,DNAJC3,HEXB,RET,DHX8,TGOLN2,MORF4L2,SYTL4,DPP8,BARD1,CALM2,DAPK2,WEE1,PQLC2,PSMD1,AP1M2,MUC4,UBE2T,CABP1,CYP2S1,FUT1,TUBG1,ACOX2,MGAT5,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,MTRF1L,TFAP2C,PRKAR2B,LOXL2,ICMT,CYP4F3,COL12A1,ENPP1,PLCG1,MID1IP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,HDAC1,MRPS28,TMOD2,ARF6,HSPB1,NXT2,FAM169A,ALDH6A1,GGA1,NUAK1,SOX9,RAB23,SLC36A4,COX6C,FAM21C,LMNA,MARCH8,GNS,FRY,ATP5H,FLRT3,RANBP1,NEK2,PCYOX1,CADPS2,MYDGF,NCAM1,NDUFA12,NUP85,C9orf72,PPP6R1,MCCC2,REC8,KIF20A,SALL4,STAT4,PYM1,ERO1A,MYBL2,ELK1,TP53INP2,SPTLC2,GNA11,PSMA4,SFXN5,DCP2,CYB5A,DHX32,SCARB2,NCOA3,ETS2,TIMM8A,SETD3,ITPR1,AURKA,MDH1,GDF11,NDE1,ARPC2,CFAP20,NUP58,TMEM173,RUSC1,CCDC109B,GRHL2,GALNT12,ACTR8,RGS20,PKP2,TESK2,NUF2,MGST2,MVB12B,PRKACA,APC2,APPBP2,CDS1,CCND1,RCN1,MUC16,SCNN1A,CDH1,SP100,DACT1,XYLT2,ACSL4,ARL4D,RAB27B,CDKN2D,ZNF365,MYT1,ETV4,SNX10,TMEM9,MX1,CAMSAP3,SEC61B,COL6A2,FZD4,SEPT6,SYNE2,HTATIP2,CDCA2,NUSAP1,DNAJB14,RAB38,XRCC6BP1,GTF2A2,COX20,GABARAPL1,SHROOM3,WFS1,SLC9A6,PNPLA6,RGS14,SLC25A30,MAPK12,TTC8,CKAP2,DCAF7,ESRP1,SDC4,HABP4,RASSF7,PDIA3,CTSZ,PKN1,TMA16,NUCB2,ETS1,SLC25A43,PDIA4,SGPL1,NEO1,CTNNBIP1,DTX3L,ADD3,FUT2,CTSC,ARSG,ANKS1B,CALD1,ALG13,MGAT4A,FAM20B,CST3,BAX,KLC3,PLEKHF1,ECI2,TMBIM6,MAPK11,TPCN1,S100A6,MED22,CRTAP,PARP9,ACBD5,LCA5,PLSCR1,TACC1,FMN1,BCL9,PIK3R1,EIF5A2,ELOVL3,MRS2,UBE2A,AK4,GALNT3,RPL12,PLOD2,RAB11FIP2,NR1D2,SYT7,DBI,NR4A3,CENPE,HMGA1,CMPK2,USF2,ACOT7,MYL9,EPAS1,CUL4B,EPHA4,ARFGEF1,NDC80,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,HDAC6,PDGFB,NUP62CL,SDC1,SPTB,FANCI,RPS6KA2,CNTRL,SLC44A1,ABCA2,DUSP10,SCARA3,TRAM1,CCDC38,SMAGP,PLK1,THRB,PCGF5,ING1,STAU2,CBX6,NFE2L1,EZR,KLK6,ARFRP1,ANLN,PRKRA,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,KDM4D,DZIP1L,HS6ST1,PLEKHG6,MSL1,AGPAT2,KLF12,MAP2,WIPI1,P4HA2,DOLPP1,ZNF367,RAB11FIP1,PIEZO1,MYL12B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,HJURP,LGALS3,CHCHD7,FXYD3,HLA-F,ASAH1,RAB6A,B4GALT4,DHRS3,B4GALNT1,DAZAP1,GATA2,KIF13B,TBCD,SELK,MDFIC,FAR2,WNT3A,MPHOSPH9,ALDH3A2,CKAP4,C9orf9,CYP26B1,CHSY3,MRPS33,MGAT4B,SPATA13,EMC2,SCRIB,TCF7,PDK3,G2E3,CDK5R1,MAPKAPK2,EPN3,COQ10A,H1F0,COL13A1,MFSD2A,P4HA3,ZDHHC7,PLD1,TMEM120A,CCNB2,USP43,NF2,HOXB7,UPF3B,FOXM1,P3H2,XYLT1,TP53,ERBB2,FAM198B,LPIN3,STIL,EMP2,BCAP31,CYP26A1,TTC21B,PDGFA,ATP6V0B,WDR44,N4BP3,BCL6,PLK4,VAT1,ESPN,NOTCH3,OAS3,MINPP1,LMAN1,EGLN3,CTDSP2,GM2A,SULF2,CPD,SIRT1,PPIF,CLCN3,ERLEC1,EVA1A,AKT1,FIGNL1,COQ10B,CCSAP,CDC20,SERTAD3,MYL12A,DAG1,ATP13A2,TAPBP,DNAJC10,IDE,RBL1,STK38,IRF7,AIFM3,LTA4H,ST3GAL1,NDST3,ARFGEF3,MAN2B2,COL9A3,CMAS,PINK1,PACSIN2,GOLIM4,CD63,BLVRB,SWI5,CDCA8,ERI2,PSMD10,GTF3A,HMGN3,NKRF,CRABP2,DSE,LBR,AIP,VPS26A,PARM1,DNAJB9,H1FX,FZD6,M6PR,ZDHHC21,CCDC92,GTF2F2,FAM63A,TFAP2A,UBE2J1,SGK1,BUB1,ALDH7A1,ABCD1,KLF9,GCNT1,HES1,RHOA,PSMB4,NR3C1,IFITM3,GUSB,AMFR,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,FNDC3A,BCAR1,BBS2,TXNDC11,MAPK8IP1,FUCA1,SERPINA1,CDCA7L,NMI,PGRMC1,PPP2R3C,SH3BGRL2,SPCS3,NDFIP1,UBE2C,TBC1D4,PTGES,HIPK3,ZBTB33,DIS3L,GOLGB1,SUN1,LAMP1,GAA,SLC35D2,TXN,SSH1,HSPG2,ATP8A1,TAP1,PSME1,CCNB1,PJA2,OAT,FAM101B,CENPN,NCS1,SLC9A7,CYP1A1,STIM1,RGS3,OSBPL3,STEAP2,IRF2,SNX16,HYLS1,MARCH2,ZBTB18,PACSIN1,LAMP2,LOC81691,KIFC2,SPATA18,SNTB2,SLC35C1,KIF13A,PIF1,GALNT7,CCNF,MCFD2,SLC25A5,POR,PRIM1,AHRR,SLC25A4,PLK2,GNPTAB,FAM110C,SARAF,TRAF5,MRPL44,SCOC,TMEM55B,HLA-E,DGKQ,SLC25A27,KIF23,NDUFA4,SLC1A3,PSIP1,KIAA1161,BMP2K,MECOM,DOPEY2,SNX18,ZNRF2,VASN,RPL39,BDH1,TPST1,SORL1,PIKFYVE,GPR161,FAM69A,FADS2,DDB2,PMPCB,PRODH,B3GNT7,MMD,LPGAT1,CALM1,VEZT,ATP8B3,ANTXR1,JADE2,NFIB,DGKH,PLEKHH2,PRKAG2,FAM64A,FAAH,FAM83D,AGBL5,SFMBT1,NR4A2,CABIN1,PLIN3,MAP3K5,HOOK1,NRBP1,EHD1,PLA2G4A,SPRED1,SLC2A4,ARMCX3,CEP70,DLGAP5,NLRX1,TRIP10,THRA,RPS6KA1,IQGAP1,CCDC110,ATP2C2,BCL2L1,SNN,AIFM2,CYP39A1,MNS1,ZFYVE9,ACAP2,CDKN1B,PDE4D,LGMN,TSPAN1,NR2C1,MED30,GPX4,ATG4D,MYO5B,SEC23A,COG2,CAPN6,FOXJ2,LYRM1,UTRN,KIF1C,SLC11A2,RAD17,PKMYT1,PYGO1,ITPR3,H2AFV,TRIQK,ATP10D,SP4,NIN,CEP162,DDOST,PPP2R5A,STK26,TRIOBP,SLC27A1,KLF5,HS3ST3B1,SLC27A3,NR3C2,COBL,CBX7,DEPDC1,ATP9A,CENPI,FBXO6,SPR,DNAH3,TEAD3,HLA-A,SLC25A36,AKIRIN1,FAM111A,PHF7,PTEN,FUT8,DRAM1,CD9,SLC44A2,CITED2,CNPY3,SPRY2,NCOA2,PDGFC,TGIF1,ZWINT,B3GNT2,ALDH2,ZC3H11A,FURIN,PARP4,C1GALT1C1,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,GPLD1,DCTN6,NUCB1,ACADSB,FGFR2,CSTF2,ERAP1,GPER1,WDR62,FZD5,NCAPG2,ARSB,SLC25A38,ESPL1,ESYT2,JARID2,CASP3,CRYM,CPT2,MPP5,SLC8B1,ERP29,TRIM68,TSEN34,SH3KBP1,ABCD4,CHPF,ZFYVE16,RAB15,GRHL1,ZCCHC12,SIVA1,DPYSL2,CEP78,PHTF1,DLG1,AKR1B1,ANKRD12,SUN3,RAB20,RP2,MYH14,CTTN,TECR,MYRIP,RASGRP1,LAMP3,CYP1B1,ATL1,TRIM8,CENPA,PTGFRN,MRPS36,MAN2A2,NEIL1,GPRC5B,HPSE,GLA,NRGN,RAP1GAP,NR2C2,PCSK5,STARD3NL,LASP1,PIFO,PEX6,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,SUCO,HLA-C,ZRANB1,LRIF1,ETV7,GAD1,SNX7,TPGS2,KDELR1,ELK3,OXR1,GYLTL1B,HMG20B,PDIK1L,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,GLCE,FECH,GNAS,NUDT16,UAP1,PLPP3,UTP14C,TMEM30A,CDCA5,CTSA,SHROOM2,APOL2,COL16A1,RARG,GAS2L1,CCNE2,DYNLRB1,SLC25A24,SORBS1,SPC25,IL15,PSME2,HDAC11,PDIA5,MORC4,COL18A1,PHLDA1,LRRC45,SLC25A48,SS18,SETDB2,CYP4F11,KIF14,REEP1,RPN2,ECE1,PDIA6,SEPHS1,CHP1,OSTM1,C3orf52,ERBB2IP,DUSP4,FANCE,CASP4,JADE1,ALDH5A1,BFSP1,PEX2,TLE1,SPTBN5,CYP2U1,REEP4,GLIS3,ANXA3,FBLIM1,SORT1,POC1B,COL4A5,INTS8,POMGNT1,HMGXB4,HDAC9,SAC3D1,TMEM63A,IRF2BPL,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,GALNS,RRBP1,TOX2,KIAA0319,CLIP2,MYO5A,B3GALT6,SUN2,SYPL1,RAB3B,ASPM,NR4A1,RC3H2,SYBU,RGCC,OGDHL,RUNX3,CTSL,HLA-B,RND3,TRIM69,DHRS2,HNRNPH2,CTSV,RAP2C,ARRB1,MCUR1,HOXB13,GEM,SOX8,PLOD3,CEP41,ZMIZ1,AHR,ABCG1,SNPH |
| 9.375e-06 | -11.58 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 118 | 28 | 17758 | 1761 |
PDGFC,COL9A3,COL6A2,AKT1,NR4A1,PIK3R1,CALM1,CASP9,FURIN,CALM3,COL4A5,PRKAR2B,ITPR2,ITPR3,PHLPP1,BCAR1,PRKACA,PDGFB,CDK1,RASA1,CALM2,PDGFA,PLCG1,ADRBK1,PTEN,COL6A1,PIK3CA,CDKN1B |
| 9.404e-06 | -11.57 | BHAT_ESR1_TARGETS_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 269 | 50 | 17758 | 1761 |
IER5L,KLK10,ARAP3,PARP12,RET,EFHD2,GDF15,SLC7A2,DHRS3,FAM46C,LTBP3,NCS1,CYP26A1,IER3,C16orf74,CCND1,SCNN1A,MLPH,CYP4F11,A4GALT,REEP1,TMEM51,FAM102A,TIPARP,TIAM1,SULT2B1,OSGIN1,CYP1B1,SEMA3B,PPIF,SUSD3,CELSR2,SYBU,MYEOV,ASB13,FOS,ALDH3B1,SLC6A6,PRKAG2,SMTNL2,TJP3,PDLIM3,DHRS2,MFSD2A,WFS1,LRIG1,NOD2,FAM195A,GLA,PTGES |
| 9.426e-06 | -11.57 | apoptotic process | biological process | GO:0006915 | 1059 | 151 | 16441 | 1675 |
LAMP1,CASP3,ADD1,RET,PSME1,SH3KBP1,DAPK2,RPS6KA2,PSMD1,CTGF,ELMO2,SIVA1,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,STK17B,CDK1,POR,ABR,SLC25A4,DNM1L,MADD,KLF11,UNC5B,ARF6,TRAF5,FGD1,BMF,NCKAP1,PHLPP1,ADAMTSL4,TNFRSF19,LMNA,MECOM,TFAP4,CYR61,MAP3K9,DAPK1,SELK,CD70,TNFRSF12A,MYDGF,PIM1,WNT3A,PRODH,ERO1A,SCRIB,PSMA4,G2E3,FAS,STK17A,H1F0,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,TMEM173,XDH,PSME2,RPS6KA1,INPP5D,TP53,BCL2L1,AIFM2,PHLDA1,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,CDKN1B,DAB2IP,SCN2A,EGLN3,F2R,CDKN2D,ATG4D,SIRT1,PPIF,MX1,EVA1A,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,EFNA5,AIFM3,ZMAT1,GCLM,SORT1,NKX3-1,ARHGEF3,ARHGEF11,CKAP2,DAP,RASSF7,PSMD10,TGFBR1,PKN1,BEX2,SGPL1,TOP2A,CARD8,ADORA1,CTSC,PTEN,CST3,DRAM1,BAX,SGK1,ADAM15,TMBIM6,PLEKHF1,BUB1,ERBB3,FAIM,RHOA,PSMB4,PLSCR1,GCLC,PLAUR,PIK3R1,LITAF,CTSL,FGFR2,TRIM69,ARRB1,UACA,GPER1,ITGAV,FZD5,ARHGEF9,AHR,HIPK3,ESPL1,MELK,OCLN,ARHGEF4 |
| 9.442e-06 | -11.57 | BAE_BRCA1_TARGETS_UP | MSigDB lists | BAE_BRCA1_TARGETS_UP | 70 | 20 | 17758 | 1761 |
LAMP2,GAA,LGALS3,EPAS1,DRAP1,SAT1,NDUFA4,COL4A5,GTF2A2,PRDX4,NOV,KCNK1,BMP7,SPINT2,RYK,SORL1,MTMR11,TRAM1,SEPHS1,ABCG1 |
| 9.480e-06 | -11.57 | gland development | biological process | GO:0048732 | 394 | 68 | 16441 | 1675 |
FOXM1,THRA,RPS6KA1,CAST,ERBB2,PLXNA1,DDR1,CACNB4,CCND1,CYP1A1,CDH1,LMO4,ELF5,PIK3CA,ETV4,AKT1,EZR,TFAP2C,ICMT,DAG1,IRS2,MDK,ATP7B,HOXA9,NRG1,ARF6,E2F8,COBL,CBX7,CAPN1,NKX3-1,CDKN1C,SERPINE2,SOX9,TGFBR1,ETS1,SIX4,ZDHHC21,ELF3,E2F7,IGF1R,PTEN,GATA2,BMP7,CST3,CITED2,WNT3A,SLC12A2,IGSF3,HES1,AK4,SCRIB,NPHP3,NFIB,PITX2,NCOA3,ONECUT1,TWSG1,FGFR2,CSF1,HOXB13,CCNB2,SEMA3A,USF2,RARG,AHR,JARID2,XDH |
| 9.500e-06 | -11.56 | glycoprotein metabolic process | biological process | GO:0009100 | 447 | 75 | 16441 | 1675 |
HSPG2,GALNT12,XYLT1,HEXB,FBXO2,NANS,MGAT5B,SDC1,PHLDA1,CHPF,MUC16,MUC4,IMPAD1,XYLT2,FUT1,RPN2,LMAN1,TIPARP,MGAT5,SULF2,SIRT1,SEC23A,TNIP1,GALNT7,MCFD2,ARF4,MAN2A2,HS6ST1,HPSE,DDOST,DOLPP1,GNPTAB,HS3ST3B1,ST3GAL1,NDST3,CMAS,SDC4,GNE,PDIA3,CTSZ,FBXO6,B4GALT4,POMGNT1,DSE,ADAMTSL4,B4GALNT1,B3GALNT1,FUT2,CTSC,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,PPP6R1,TRAK2,GCNT1,GFPT1,B3GALT6,CHSY3,B3GNT7,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,FOXL1,GLCE,FUCA1,GALNT3,UAP1,SERPINA1,CTSA,ARSB |
| 9.501e-06 | -11.56 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | 191 | 39 | 17758 | 1761 |
GRN,FBLIM1,ALDH6A1,ST14,HLA-E,RASA2,CTDSPL,PPFIBP2,IL18,CAMK1D,DNER,FAM101B,FAM46C,IL18R1,LTBP3,DNAJB9,CCND1,FAM102A,TSPAN1,PTPRE,SPRY2,S100A6,S100A4,PLAUR,MGAT4B,ARFRP1,PCTP,STK17B,FRMD4B,NFKBIA,FAM114A1,BMP1,PRDM5,ITGAV,GEM,ABCA1,GAB1,CPPED1,KLF7 |
| 9.501e-06 | -11.56 | GSE20715_0H_VS_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_UP | 191 | 39 | 17758 | 1761 |
DYNLRB1,PARP12,PPFIBP2,FHDC1,SELL,PKP2,FAM198B,EMP2,ETS1,BEX2,NRP2,PPP2R3A,PDGFA,CDKN2C,MDM1,CA2,PLCG2,TRIM21,TSPAN13,ALDH7A1,RFX5,MYLIP,EPB41L5,PRODH,PMPCB,ARAP2,HPS3,PLEKHA6,ELK3,MPP1,ARHGDIB,TCF7,EPHA1,DCTN6,HLA-B,SLC6A6,SEMA4D,SERPINB1,GAB1 |
| 9.501e-06 | -11.56 | GSE20366_TREG_VS_TCONV_DN | MSigDB lists | GSE20366_TREG_VS_TCONV_DN | 191 | 39 | 17758 | 1761 |
LGALS3,DNAJC3,ESRP1,SPR,FAM101B,DENND2D,HLA-A,SESN3,RALGPS2,RINL,MGAT4A,SGK3,CCDC82,ALDH7A1,ECE1,ANO4,MYLIP,FAM69A,CYP1B1,HPS3,GCLC,NUB1,ASB13,ANLN,DOCK5,RNF19B,C3orf58,CASP4,DGKE,EDNRA,RASGRP2,XKRX,MID1IP1,ANKRD6,TRIOBP,ABCB1,PER3,ARSB,ESPL1 |
| 9.501e-06 | -11.56 | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | 191 | 39 | 17758 | 1761 |
SPRED1,CDK17,NFKBIE,FRMD6,CALB2,OSGIN2,KCTD12,GDF15,PDGFB,PHLDA1,STIL,TNFSF9,CYR61,FLRT3,BCL6,RAB20,CITED2,TIPARP,C9orf72,GFPT1,TGIF1,RIPK2,PLSCR1,PLAUR,USP18,RAPGEF2,COQ10B,PTGER4,FAM133B,DUSP4,RNF19B,FOS,ZFAND5,CD83,FGD6,ITGAV,MAFF,KLF7,EHD1 |
| 9.589e-06 | -11.55 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 962 | 136 | 17775 | 1757 |
CCNI,ACACB,CAMKK1,EPHA4,RET,MPP5,CAMK1D,ITPR2,PLXNA1,SLC20A1,CDKN2C,DAPK2,WEE1,SIPA1L2,RPS6KA2,CTGF,ELF5,KCNS3,PIK3CA,DDX59,PLK1,TNIP1,ACVR1C,PBK,ROR1,GALNT7,CCNF,IDH1,ADRBK2,STK17B,TMEM164,PLK2,ATP7B,LIMK1,DHTKD1,PRKAA2,CDK17,ADCK5,MERTK,BMP2K,UBE2Q2,IGF1R,FRY,SNX18,NEK2,DAPK1,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,ETV7,ABCC1,PRSS23,BTNL9,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,STK17A,GLCE,GNAS,BCAR3,MAPKAPK2,SEMA4D,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,PSME2,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,MNS1,ZNF687,CDH1,PLK4,EPHB4,SCYL3,MAP3K3,AKT1,RIPK2,FZD4,FIGNL1,SYNE2,PRKCQ,PKMYT1,ITPR3,MAP3K6,EPHA10,JAK1,CDK19,AXL,STK38,PTK7,MLKL,MAPK12,PINK1,TGFBR1,PKN1,TRIB2,M6PR,ADD3,ADRBK1,PTEN,CDK16,SGK3,SGK1,BUB1,MAPK11,ERBB3,SYK,TGIF1,ASPM,PIK3R1,YES1,FOS,FAT4,FGFR2,ACVRL1,ABCB1,CCDC69,UACA,ARRB1,HIPK3,MELK,GOLGB1 |
| 9.650e-06 | -11.55 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 205 | 41 | 17758 | 1761 |
IER5L,KLK10,RET,MORC4,SYTL4,DHRS3,FAM46C,NCS1,CCND1,C16orf74,SCNN1A,MLPH,CYP4F11,A4GALT,LHX6,REEP1,TMEM51,FAM102A,SULT2B1,TIPARP,TIAM1,OSGIN1,CYP1B1,SEMA3B,SUSD3,CELSR2,PRSS23,SYBU,MYEOV,ASB13,CDK5R1,TJP3,SMTNL2,PDLIM3,DHRS2,MFSD2A,WFS1,LRIG1,SOX8,PTGES,RAB3IL1 |
| 9.794e-06 | -11.53 | guanyl-nucleotide exchange factor activity | molecular function | GO:0005085 | 194 | 40 | 16491 | 1673 |
ARHGEF3,ARHGEF11,ARFGEF1,SBF1,ARHGEF40,DENND2D,ARHGEF16,EPS8L2,ARHGEF10L,ST5,RALGPS2,ARHGEF37,RINL,RASGEF1A,TIAM1,ALS2CL,RASGRP1,FARP2,DOCK4,RASGRF1,ARHGEF28,RAPGEF2,SPATA13,DOCK5,ABR,ARHGEF26,RASGRP2,BCAR3,PLEKHG6,ARHGEF19,MADD,PLEKHG1,FGD6,ARHGEF9,RAB3IL1,ARHGEF4,ARFGEF3,DOCK9,FGD1,DENND5B |
| 9.834e-06 | -11.53 | CYTOPLASM | MSigDB lists | CYTOPLASM | 2079 | 263 | 17758 | 1761 |
LAMP1,SSH1,AASS,MRPS15,SLC25A13,DNAJC3,PSME1,TGOLN2,ISOC2,OAT,BARD1,SLC9A7,CALM2,CDKN2C,DAPK2,STIM1,RGS3,ZFP36,STEAP2,FUT1,TUBG1,TACSTD2,ERAP2,METAP2,LAMP2,SGCE,SH3BGRL,SNTB2,CDA,ICMT,POR,PLCG1,SLC25A4,DNM1L,LIMK1,ATP7B,NOD2,HDAC1,SERPINB6,MRPS28,ARF6,HSPB1,F2RL1,FGD1,NFKBIE,CDKN1C,GGA1,SLC25A27,NDUFA4,ATG4A,DOPEY2,RANBP1,NEK2,TRAK2,KIF20A,LPGAT1,CALM1,NPC2,GNA11,STX3,AP1AR,PLEKHH2,FGD6,MDH1,PLIN3,NDE1,EGLN1,SLC2A4,DLGAP5,NQO1,S100A11,DDIT4L,PTTG1,BCL2L1,AIFM2,RCN1,CDH1,CDKN1B,PHKA2,SULT2B1,CDKN2D,ATG4D,SEMA3B,GPX4,MX1,SEC23A,SEC61B,COG2,HTATIP2,KIF1C,PKMYT1,ITPR3,GABARAPL1,NIN,PPP2R5A,DDOST,SLC9A6,ISOC1,MAPK12,DCAF7,PDIA3,CTSZ,NUCB2,GSTP1,PDIA4,FUT2,PTEN,CTSC,ARSG,BAX,ECI2,TMBIM6,SGCB,S100A6,MED22,FARP2,SHMT1,PIK3R1,FURIN,SNTB1,CRISPLD2,NUCB1,ACADSB,PLOD2,ERAP1,ARSB,ESPL1,ACOT7,MYL9,TRIM2,DNAJB11,MPP5,ITPR2,HDAC6,ERP29,DNER,SPTB,ARHGEF10L,BTG3,CNTRL,TMEM143,ABCA2,DUSP10,CTTN,TRAM1,NEB,LAMP3,PLK1,PCGF5,EZR,ARHGDIB,KLK6,ROR1,ANLN,PRKRA,IDH1,MRPS36,DZIP1L,OPTN,PLCH1,AGPAT2,WIPI1,DOLPP1,MADD,GLA,RAP1GAP,PCSK5,RRAGD,CD99,LASP1,ARAP3,ZNF395,LGALS3,PEX6,PDCL,CALM3,RAB6A,CA2,KIF13B,PIM1,ZRANB1,MPHOSPH9,CCDC88A,KDELR1,MDFI,RGMB,PCBP3,STRADB,PDK3,CDK5R1,GLCE,GNAS,CDCA5,NFKBIA,CTSA,PLD1,SHROOM2,IFI6,LMO7,DYNLRB1,NF2,IL15,PDIA5,TP53,SYTL2,FABP6,REEP1,RPN2,LMAN1,MINPP1,PDIA6,F2R,SCYL3,DVL2,GCA,CLCN3,AKT1,ACO1,GLO1,ERBB2IP,TAPBP,IDE,ALDH5A1,PEX2,SECTM1,IRF7,SYT13,ANXA9,AIFM3,ABCA1,ANXA3,PACSIN2,GOLIM4,PINK1,CD63,GNE,TRIB2,DSE,AIP,DNAJB9,VPS26A,SAC3D1,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,RRBP1,BUB1,MYO5A,B3GALT6,NR3C1,AMFR,PRICKLE1,BCAR1,MAPK8IP1,SPINT2,NMI,ARRB1,CEP41,PLOD3,GOLGB1,ABCG1 |
| 9.865e-06 | -11.53 | MODULE_2 | MSigDB lists | MODULE_2 | 374 | 64 | 17758 | 1761 |
MYL9,LTBP1,TRIM2,HSPG2,S100A11,THRA,EMP2,IER3,CCND1,LMO4,ALDH1A3,BCL6,GOT1,NOTCH3,CYP1B1,MX1,SGCE,MBP,COL6A2,S100A4,ITPR3,ALCAM,DPYSL3,OPTN,TLE1,MAFF,PCOLCE,CDKN1C,IGFBP6,ENO2,ITGA6,DNAJB2,ATP9A,EPS8,BLVRB,ASAH1,GDF15,TRIB2,FBLN1,DHRS3,SEPP1,TSPAN7,CYR61,COL6A1,ERBB3,NCAM1,HES1,FADS2,MMD,NR4A1,FOS,LEPR,CYB5A,TIMP3,ETS2,SCG2,ITGA7,DTX4,TCEAL4,NR4A2,LTBP2,GEM,AHR,L1CAM |
| 9.930e-06 | -11.52 | LU_AGING_BRAIN_UP | MSigDB lists | LU_AGING_BRAIN_UP | 255 | 48 | 17758 | 1761 |
ANXA3,LTBP1,CAST,IQGAP1,ZCCHC24,LRP4,GNE,RGS20,COL4A5,PHLPP1,SEPP1,DHRS3,DDR1,ADD3,METTL7A,PAIP2B,FRYL,CALD1,BMP7,VAT1,ERBB3,TIPARP,CYP1B1,SEMA3B,LAMP2,AMOTL2,SYPL1,TGIF1,LITAF,YES1,MYL12A,DPYSL3,MFAP3L,PDLIM3,SLC4A4,GPRC5B,PLOD2,FGFR2,WIPI1,WFS1,NFKBIA,LRIG1,IRF7,ITGAV,MAP3K5,TOB1,NXT2,ABCG1 |
| 1.011e-05 | -11.50 | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | 76 | 21 | 17758 | 1761 |
FBLIM1,TGIF1,MBP,UGT8,CDC20,EPS8,PTTG1,UTRN,SLC1A3,CCNB1,IFIT3,SDC1,CDK1,SLC4A4,PLOD2,BCL6,TNFRSF12A,IGFBP2,PER3,F2R,UBE2C |
| 1.017e-05 | -11.50 | ESC_J1_UP_EARLY.V1_UP | MSigDB lists | ESC_J1_UP_EARLY.V1_UP | 171 | 36 | 17758 | 1761 |
PRSS8,SERPINE2,IL15,THRA,FXYD3,CD82,TRIB2,TYMP,SESN3,SCNN1A,ST5,CYP2S1,A4GALT,BMP7,ENPP5,NEK2,CDKN1B,CDH3,C10orf54,TSPAN1,NAGA,TLE6,ADCK3,CORO2A,PIK3R1,PTGER4,LOXL2,PCTP,GDE1,C19orf66,P4HA2,WBSCR27,CPPED1,RAB3IL1,CD33,ABCG1 |
| 1.021e-05 | -11.49 | blood coagulation | biological process | GO:0007596 | 525 | 85 | 16441 | 1675 |
PLA2G4A,MYL9,PAPSS2,INPP5D,TP53,F11R,ITPR2,PRKACA,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,LMAN1,F2R,RASGRP1,LAMP2,ENPP4,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,HABP4,DGKQ,SELL,KIF23,CALM3,FBLN1,MERTK,FZD6,SIRPA,ITGA3,GATA2,CD9,PRKG1,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,L1CAM,EHD1,DOCK9 |
| 1.023e-05 | -11.49 | antigen processing and presentation of endogenous peptide antigen via MHC class I | biological process | GO:0019885 | 10 | 7 | 16441 | 1675 |
ERAP1,HLA-B,TAPBP,HLA-C,ERAP2,HLA-A,TAP1 |
| 1.025e-05 | -11.49 | EF_HAND_2 | prosite domains | PS50222 | 217 | 44 | 11866 | 1235 |
MYL9,SLC25A24,REPS2,S100A11,SLC25A13,CALB2,CALM3,EFHD2,NUCB2,S100A2,HPCAL4,REPS1,NCS1,PPP2R3A,PLS3,CALM2,RCN1,CABP1,DGKG,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,AIF1L,MCFD2,MYL12A,RASGRP2,NIN,NUCB1,PLCH1,PLCG1,DUOX1,SWAP70,GNPTAB,CGREF1,NKD1,S100A5,EFCAB14,CAPN1,EHD1 |
| 1.043e-05 | -11.47 | EF_HAND_1 | prosite domains | PS00018 | 177 | 38 | 11866 | 1235 |
MYL9,SLC25A24,REPS2,S100A11,CALB2,CALM3,NUCB2,S100A2,REPS1,HPCAL4,PPP2R3A,NCS1,PLS3,RCN1,CALM2,CABP1,DGKG,S100A6,RASGRP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,MCFD2,MYL12A,RASGRP2,NUCB1,DUOX1,PLCH1,PLCG1,GNPTAB,NKD1,CGREF1,S100A5,PPP2R3C,CAPN1,EHD1 |
| 1.045e-05 | -11.47 | JISON_SICKLE_CELL_DISEASE_UP | MSigDB lists | JISON_SICKLE_CELL_DISEASE_UP | 178 | 37 | 17758 | 1761 |
GAS2L1,MYL9,ANXA3,TXN,NFKBIE,IL15,GNPDA1,PSME2,BLVRB,TAP1,TP53I11,SNN,HLA-A,TYMP,IQCE,MITF,CD9,IFIT1,NOTCH3,GM2A,LAMP2,MX1,MICB,MPP1,HTATIP2,BLVRA,ATP1B1,IFIT3,LHFPL2,SPTLC2,RHEB,PRDX4,NUCB1,H1F0,AXL,CTSA,PLIN3 |
| 1.046e-05 | -11.47 | MODULE_66 | MSigDB lists | MODULE_66 | 531 | 84 | 17758 | 1761 |
TRIM2,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,APC2,PHLDA1,CABP1,LMO4,ALDH1A3,IFIT1,BTBD3,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,TLE1,SERPINI1,ITPKA,NRGN,BIN1,WASF3,COL9A3,CDH22,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,SOX9,CALB2,GABRG2,CNTNAP2,SLC1A3,SEPP1,TSPAN7,PARM1,NEO1,ELF3,DIRAS3,CA2,RIMS3,ALDH7A1,IGFBP2,NCAM1,GAD1,PLCB2,RIMS2,ATP2B1,FADS2,NR4A1,BCL9,GRIN1,FOS,TIMP3,SERPINA1,FGFR2,SCG2,RND3,ITGA7,ITPR1,TCEAL4,CDK18,STK39,L1CAM,PKIA,SNPH,ARHGEF4 |
| 1.053e-05 | -11.46 | GUO_HEX_TARGETS_UP | MSigDB lists | GUO_HEX_TARGETS_UP | 82 | 22 | 17758 | 1761 |
CD99,FZD4,IQGAP1,EPHA4,CALM1,CALM3,DIAPH2,RAB6A,STIL,CMTM6,ABCD4,CALM2,PGF,SLC6A6,IGF1R,PTEN,IMPAD1,KLF9,LIFR,KLF7,FGD1,RRAGD |
| 1.056e-05 | -11.46 | AMUNDSON_GENOTOXIC_SIGNATURE | MSigDB lists | AMUNDSON_GENOTOXIC_SIGNATURE | 100 | 25 | 17758 | 1761 |
GFPT1,NFE2L3,DDB2,CENPA,ZWINT,PKMYT1,PHLDA1,FOS,SAC3D1,ELF3,CDKN2C,SP100,SEMA4D,AXL,SIVA1,NR4A3,BMP1,AURKA,IRF2,BUB1,ACSL4,GEM,SPRY2,RARG,GAB1 |
| 1.066e-05 | -11.45 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | 185 | 38 | 17758 | 1761 |
BIN1,ENO2,FAM169A,ITGA6,NUCB2,TRIB2,ETS1,FAM46C,LTBP3,DENND2D,HSF2,GNB5,MGAT4A,PASK,FAM102A,PDE4D,MYLIP,FBLN5,SYNE2,PIK3R1,STMN3,PRKCQ,ITPR3,SESN1,PLCG1,NGFRAP1,AMMECR1,LRIG1,INPP4B,TBC1D4,TMEM14A,TRAF5,SLC25A38,HSPB1,NR3C2,PKIA,SNPH,DOCK9 |
| 1.070e-05 | -11.45 | TGACCTY_V$ERR1_Q2 | MSigDB lists | TGACCTY_V$ERR1_Q2 | 978 | 138 | 17758 | 1761 |
SLC25A13,FHDC1,NDRG2,OAT,DNER,DENND2D,LTBP3,SLC9A7,NKAIN3,CYP1A1,RPS6KA2,STIM1,IMPAD1,RGS3,MITF,STEAP2,SERINC2,CLDN4,MANF,PACSIN1,ANO4,BTBD3,CCDC38,CBX6,NFE2L1,SLC25A5,RNF19B,ABR,PGF,SLC25A4,KLF12,KCNK1,MADD,MRPS28,PIEZO1,ARF6,ITPKA,HOXC13,NR2C2,PCSK5,RRAGD,SCN5A,SLC25A27,C6orf106,FAM81A,FBLN1,HPCAL4,TSPAN7,MECOM,ELF3,DAZAP1,CA2,SLC16A6,RANBP1,NEK2,SORL1,TNFRSF12A,RFX5,PIM1,ZRANB1,RIMS2,TRAK2,STRADB,TCF7,RASGRP2,BCAR3,EPN3,ITGA7,SLC4A3,S100A5,MDH1,KLF7,NCKAP5,SLC2A4,UGP2,TRIP10,DDIT4L,XYLT1,OSR2,FAM198B,CYP39A1,ZFYVE9,EPS8L2,ST5,ZNF687,SCNN1A,XYLT2,DACT1,DOK4,BCL6,GOT1,NR2C1,SAT1,PANK1,KIF1C,ATP1B1,GABARAPL1,NFIX,ADAMTS14,NRG1,ANXA9,ST3GAL1,AIFM3,LIFR,SORT1,TM2D2,PDIA3,GABRG2,PKN1,CRABP2,SIRPA,PPP2R3A,ZDHHC21,IRF2BPL,KIF5B,CCDC92,CDK16,RRBP1,ADAM15,WWP1,TAGLN2,NCOA2,OSGIN1,FBLN5,LCA5,BCL9,OGDHL,CRISPLD2,ARHGAP24,PITX2,RND3,CCDC69,FHL1,NDFIP1,ZBTB33,SNPH,TLL2,JARID2 |
| 1.070e-05 | -11.44 | ameboidal-type cell migration | biological process | GO:0001667 | 154 | 34 | 16441 | 1675 |
SEMA6B,RET,TGFBR1,NCKAP1,PKN1,S100A2,EMP2,EFNB1,FGF19,SGPL1,NOV,PTEN,MEGF8,PIK3CA,TWIST1,SEMA3G,EPHB4,CYP1B1,SEMA3B,EPB41L5,NR4A1,SYNE2,TNS1,LOXL2,ANLN,ZFAND5,GPLD1,PITX2,SEMA4D,SCG2,CORO1C,SOX8,ARSB,SEMA3A |
| 1.124e-05 | -11.40 | TGCCTTA,MIR-124A | MSigDB lists | TGCCTTA,MIR-124A | 532 | 84 | 17758 | 1761 |
GAS2L1,VANGL1,IQGAP1,CTDSPL,CACNA2D2,MORC4,KCTD12,F11R,EMP2,OSBPL3,REEP1,MITF,PIK3CA,SERINC2,ABCA2,TUBG1,VAT1,RASGEF1A,PTPRE,MYRIP,MAP3K3,SIRT1,THRB,PCGF5,CAPN6,SERTAD4,PTPN9,SERTAD3,RAD17,ICMT,ITPR3,ALCAM,COL12A1,ABR,NFIX,SLC9A6,LRIG1,SLC27A1,NXT2,RUNX2,FRMD4A,GGA1,ZCCHC24,SOX9,RAB6A,ETS1,SIX4,KIAA1161,NRP2,HMGXB4,LMNA,TMCC3,MECOM,RAVER2,MARCH8,RALGPS2,RNF128,RRBP1,OPN3,PCYOX1,LIMCH1,MYLIP,SPRY2,IGDCC4,ELK3,TACC1,NR3C1,PPARA,LITAF,DIAPH2,LRRC1,NFIB,GLCE,FGFR2,CSNK1G1,ITGA7,AMMECR1,YOD1,CDK18,PLIN3,NDFIP1,AHR,ESYT2,ARHGEF4 |
| 1.146e-05 | -11.38 | Ser-Thr/Tyr_kinase_cat_dom | interpro domains | IPR001245 | 132 | 30 | 18293 | 1814 |
LMTK3,RIPK2,ACVR1C,TESK1,EPHA4,RET,ERBB2,TESK2,TGFBR1,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,EPHA10,JAK1,IGF1R,FGFR2,ACVRL1,LIMK1,AXL,PTK7,RYK,MAP3K9,ERBB3,MLKL,EPHB4,JAK3,SYK |
| 1.158e-05 | -11.37 | - | gene3d domains | 1.20.900.10 | 71 | 21 | 9988 | 1080 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,ARHGEF4,FGD1,FARP2 |
| 1.171e-05 | -11.36 | positive regulation of programmed cell death | biological process | GO:0043068 | 566 | 90 | 16441 | 1675 |
CASP3,NQO1,INPP5D,RET,TP53,COL18A1,BCL2L1,CAMK1D,HDAC6,AIFM2,BARD1,PHLDA1,BCAP31,ARHGEF16,RPS6KA2,CTGF,SIVA1,ALDH1A3,BCL6,CDKN1B,DAB2IP,EGLN3,TIAM1,F2R,CYP1B1,SIRT1,PPIF,RIPK2,AKT1,ACVR1C,CASP9,SLC11A2,CD40,PRKRA,SAV1,STK17B,ABR,DNM1L,CDK19,NGFRAP1,KLF11,FGD1,BIN1,ARHGEF3,PINK1,BMF,NKX3-1,ARHGEF11,DAP,ITGA6,PDIA3,TGFBR1,AES,ADAMTSL4,TOP2A,TFAP4,CARD8,CYR61,CTSC,PTEN,BMP7,TFAP2A,BAX,MAP3K9,DAPK1,PLEKHF1,BUB1,TNFRSF12A,WNT3A,OSGIN1,RHOA,RAPGEF2,PLAUR,ANO6,GRIN1,RGCC,SCRIB,CDK5R1,FAS,GPLD1,STK17A,NR4A3,ARRB1,GPER1,MAP3K5,ARHGEF9,RARG,MELK,ARHGEF4,XDH |
| 1.179e-05 | -11.35 | Antigen Presentation: Folding, assembly and peptide loading of class I MHC | REACTOME pathways | R-HSA-983170 | 24 | 11 | 8202 | 867 |
HLA-B,SEC23A,TAPBP,HLA-E,HLA-F,TAP1,ERAP1,PDIA3,HLA-C,HLA-A,ERAP2 |
| 1.179e-05 | -11.35 | WHITFIELD_CELL_CYCLE_LITERATURE | MSigDB lists | WHITFIELD_CELL_CYCLE_LITERATURE | 44 | 15 | 17758 | 1761 |
TOP2A,CCNE2,PLK1,CDKN2C,CENPA,KIF20A,CDC20,AURKA,BUB1,CCNF,CCNB1,CDKN2D,CCNB2,CDK1,CKS2 |
| 1.183e-05 | -11.34 | coagulation | biological process | GO:0050817 | 527 | 85 | 16441 | 1675 |
PLA2G4A,MYL9,PAPSS2,INPP5D,TP53,F11R,ITPR2,PRKACA,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,LMAN1,F2R,RASGRP1,LAMP2,ENPP4,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,HABP4,DGKQ,SELL,KIF23,CALM3,FBLN1,MERTK,FZD6,SIRPA,ITGA3,GATA2,CD9,PRKG1,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,L1CAM,EHD1,DOCK9 |
| 1.193e-05 | -11.34 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | 71 | 20 | 17758 | 1761 |
HMMR,CCNE2,CTHRC1,MRPL44,ASPM,RET,EIF2AK1,NUSAP1,IFIT3,ANLN,FANCI,TOP2A,B3GALNT1,RALGPS2,FUT8,UNC5B,FAR2,GLCCI1,MELK,ATP2B1 |
| 1.213e-05 | -11.32 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | 186 | 38 | 17758 | 1761 |
SUN1,BIN1,LZTFL1,PINK1,HEBP1,ATP8A1,PPFIBP2,NDRG2,AES,ISYNA1,TRIB2,ERP29,LTBP3,LLGL2,STIM1,LYPD3,A4GALT,KLF3,DLG1,VAT1,WWP1,KLF9,ARL4D,PHKA2,TPCN1,REC8,ADCK3,LITAF,STMN3,ERBB2IP,NPC2,ITPR3,ATP1A1,MSL1,TCEAL4,TMEM159,KLF7,SNPH |
| 1.213e-05 | -11.32 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 186 | 38 | 17758 | 1761 |
NFKBIE,PTTG1,TGFBR1,BCL2L1,MGST2,HDAC9,IL17RB,METTL7A,SGK1,RTKN2,TAGLN2,C12orf75,SNX10,MAST4,MYO5A,GCA,SEC61B,SAT1,LYRM1,RUNX3,ATP1B1,IDH1,RANBP9,MYL12A,FRMD4B,KLHL2,SLCO4A1,SWAP70,HLF,UEVLD,WIPI1,DBI,SIPA1L1,NOD2,RAB11FIP1,CSTF2,ATP1B3,TMEM173 |
| 1.217e-05 | -11.32 | Pkinase_Tyr | pfam domains | PF07714 | 129 | 30 | 16629 | 1696 |
LMTK3,RIPK2,ACVR1C,TESK1,EPHA4,RET,ERBB2,TESK2,TGFBR1,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,EPHA10,JAK1,IGF1R,FGFR2,ACVRL1,LIMK1,AXL,PTK7,RYK,MAP3K9,ERBB3,MLKL,EPHB4,JAK3,SYK |
| 1.226e-05 | -11.31 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDM_UP | 193 | 39 | 17758 | 1761 |
GRN,TM2D2,TTC39B,CRYM,ST14,CUL4B,PTTG1,ARFGEF1,CAMK1D,GPSM2,ERP29,CMTM6,CCDC92,TFAP4,IGSF9,CTSC,PLCG2,RANBP1,TPST1,CDKN1B,TMEM37,PLCB2,BTBD3,CTDSP2,PVRL4,GCA,USP18,HMG20B,ZFAND5,RNPEP,MAPK8IP1,PLK2,LIMK1,CSF1,SECTM1,HOXB13,LRRK1,RGS14,TOB1 |
| 1.226e-05 | -11.31 | LINSLEY_MIR16_TARGETS | MSigDB lists | LINSLEY_MIR16_TARGETS | 193 | 39 | 17758 | 1761 |
LMO7,NLRX1,TMEM55B,EPHA4,KIF23,CCDC68,CARD10,SIRPA,ZFYVE9,M6PR,TFAP4,WEE1,BTG3,E2F7,RNF128,GNB5,WWP1,CRY2,NCEH1,MYBL1,TIAM1,GFPT1,RAB3B,ELK3,TACC1,MICB,CBX6,KIF1C,SLC11A2,ANLN,NUBP1,SFXN5,DCP2,RAB11FIP2,PHLPP2,LIMK1,SETD3,CLIP4,RGMA |
| 1.226e-05 | -11.31 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 193 | 39 | 17758 | 1761 |
LAMP1,CMAS,REPS2,DLGAP5,GALNT12,SLC25A13,HEBP1,ABCG2,CDCA8,KCTD12,FTH1,MGST2,MERTK,ARHGEF40,CMTM6,PPP2R3A,M6PR,PTEN,PAQR5,GALNS,MYO5A,HMMR,PLAUR,KIF1C,HTATIP2,NUSAP1,TNS1,MCFD2,ASB13,IDH1,CD83,TIMP3,CSF1,P4HA2,PGRMC1,RAB11FIP1,PLIN3,CYBRD1,ACOT7 |
| 1.234e-05 | -11.30 | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | MSigDB lists | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | 331 | 58 | 17758 | 1761 |
PINK1,RPS6KA1,CIT,DGKQ,GNE,ERBB2,TESK2,TGFBR1,TRIB2,MERTK,DDR1,NRP2,DAPK2,RPS6KA2,IGF1R,ARSG,SGK3,NEK2,PIK3CA,MAP3K9,PLK4,SGK1,MAPK11,ERBB3,PIM1,PHKA2,PIKFYVE,DGKG,MAP3K3,PLK1,RIPK2,AKT1,TESK1,ACVR1C,PBK,STRADB,EIF2AK1,ROR1,PDK3,XRCC6BP1,MAP3K6,STK17B,CDK1,CDK5R1,DGKE,STK17A,MAPKAPK2,ACVRL1,PTK7,AXL,STK38,LIMK1,NR4A3,RYK,MAP3K5,ITPKA,HIPK3,MAPK12 |
| 1.236e-05 | -11.30 | LGALS3 (lectin, galactoside-binding, soluble, 3) | protein interactions | 3958 | 166 | 37 | 16036 | 1726 |
LAMP1,MRC2,TXN,LGALS3,CD63,SLC7A2,SLC1A3,SPR,BARD1,LGALS3BP,TMEM63A,CD109,SERINC2,AHCY,ECE1,SCARA3,SLC12A2,CKAP4,MCCC2,ENPP4,LAMP2,CLCN3,OSTM1,C1GALT1C1,PTGFRN,SLC25A5,ALCAM,RPL12,ATP1A1,PTPRJ,DDOST,SLC9A6,DBI,ABCB1,PLIN3,MYL12B,CAPN1 |
| 1.244e-05 | -11.29 | BAKKER_FOXO3_TARGETS_UP | MSigDB lists | BAKKER_FOXO3_TARGETS_UP | 60 | 18 | 17758 | 1761 |
PINK1,NF2,CPEB4,CR2,ASAH1,DUSP4,SEPP1,SESN1,SIRPA,IGF1R,PNPLA6,CDKN1B,PGM2L1,ATP1B3,NCEH1,CITED2,GLCCI1,DENND5B |
| 1.254e-05 | -11.29 | lung | COSMIC cancer mutations | lung | 17159 | 1725 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.281e-05 | -11.27 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | 377 | 64 | 17758 | 1761 |
LMO7,TRIM2,UGT8,IL15,IQGAP1,DNAJC3,EPHA4,RET,C5orf30,CD274,LACTB2,SESN3,ANKRD12,IFIT1,ENPP4,TMTC1,MCTP1,USP18,C3orf52,PRKAR2B,GALNT7,DNAJB14,ALCAM,POPDC3,HOXA9,KLF5,SERPINI1,LIFR,ANXA3,CPEB4,KLHL13,MACC1,ASB9,HERC5,GDF15,TNFRSF19,ANO1,PARM1,BMP2K,SLC25A36,FOXP2,TOP2A,B3GALNT1,FAR2,FAIM,NCEH1,SLC12A2,RIMS2,LPGAT1,ASPM,SYBU,EIF5A2,OXR1,PDE5A,BLVRA,IFIT3,G2E3,NR1D2,TWSG1,DHRS2,MATN2,NETO2,CMPK2,SOX8 |
| 1.288e-05 | -11.26 | TBK1.DF_DN | MSigDB lists | TBK1.DF_DN | 272 | 50 | 17758 | 1761 |
EXPH5,CCNE2,SERPINE2,ZNF395,GNPDA1,DNAJC3,SLC25A13,GNE,COL4A5,BCL2L1,CCND1,PDGFA,ACAP2,KIF14,FLRT3,LMO4,OSBPL3,BDH1,PCYOX1,IRF2,IFIT1,SPRY2,MPHOSPH9,ATP2B1,SMARCA2,MBP,MRPS33,ZWINT,SLC39A8,SNTB2,ITCH,CBX6,GALNT7,DNAJB14,YES1,PRKRA,FOS,DCP2,GALNT3,AP1AR,NCOA3,IDE,DCK,AMMECR1,ERAP1,KLF5,HOOK1,HIPK3,PTGES,KLF7 |
| 1.290e-05 | -11.26 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 15119 | 1553 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,DPP8,FAM46C,CARD10,CMTM6,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ABR,ENPP1,PLCG1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM173,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,ZNF365,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,ZNF618,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,S100A2,TNFRSF19,TSPAN7,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,RPL39,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,SULT2B1,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ARL4D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,EFR3A,N4BP3,PLCG2,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,MAPK8IP1,CD83,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,XKR8,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,GRHL1,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,BCAR3,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,SPC25,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,ARMC7,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.301e-05 | -11.25 | V$EGR3_01 | MSigDB lists | V$EGR3_01 | 83 | 22 | 17758 | 1761 |
SIRT1,SUN2,CMAS,SCN5A,MRC2,PCOLCE,UBASH3B,HMG20B,TP53I11,PRKACA,PDGFB,HDAC9,MAN2A2,CDKN2C,RALGPS2,ITGB8,WDR44,RANBP1,KLF5,SMYD5,ETV4,C9orf72 |
| 1.306e-05 | -11.25 | G2/M DNA replication checkpoint | REACTOME pathways | R-HSA-69478 | 5 | 5 | 8202 | 867 |
WEE1,PKMYT1,CCNB1,CCNB2,CDK1 |
| 1.314e-05 | -11.24 | BENPORATH_ES_1 | MSigDB lists | BENPORATH_ES_1 | 362 | 62 | 17758 | 1761 |
CASP3,SPC25,UGP2,DLGAP5,LGR4,AASS,ESRP1,PTTG1,ERBB2,CNTNAP2,CCNB1,CRABP2,PSIP1,CYP26A1,M6PR,AKIRIN1,EPCAM,SCNN1A,AP1M2,CTSC,CYP2S1,PASK,KCNS3,SORL1,BUB1,EPB41L4B,SLC39A10,EGLN3,DLG3,GAD1,ETV4,SEPHS1,HMMR,SIRT1,NFE2L3,RAB3B,HPS3,PCDH1,KIFC2,SALL4,MICB,CDC20,MRS2,GYLTL1B,DIAPH2,EPHA1,ITPR3,CDK1,FZD7,PRIM1,CACHD1,FAM64A,GPRC5B,GNPTAB,CDCA5,LRIG1,HMGA1,MAL2,FZD5,NCAPG2,COBL,JARID2 |
| 1.324e-05 | -11.23 | GAL_LEUKEMIC_STEM_CELL_DN | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_DN | 236 | 45 | 17758 | 1761 |
MRC2,LGALS3,GALNT12,HAL,OSGIN2,CDCA8,COL18A1,NDRG2,CCNB1,PHLDA1,SIRPA,SAC3D1,TOP2A,TYMP,SCNN1A,SLC16A6,PASK,ADCK2,BUB1,IGFBP2,MINPP1,GM2A,CYP1B1,HMMR,PLK1,CENPA,COL6A2,ZWINT,ERMAP,KIF20A,NR4A1,CDC20,KLK6,NUSAP1,TNS1,YES1,CDK1,SLC6A6,SERPINA1,HPSE,SECTM1,CCNB2,ESPL1,E2F8,MELK |
| 1.330e-05 | -11.23 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | 265 | 49 | 17758 | 1761 |
EXPH5,TXN,HJURP,SERPINE2,DEPDC1,FOXM1,PTTG1,NDC80,ARL4C,BARD1,PHLDA1,CENPN,FANCI,ITGA3,RANBP1,TUBG1,TNFRSF12A,MANF,PDIA6,ETV4,SPRY2,NUP85,CKS2,GFPT1,PLK1,CENPA,ZWINT,ELK3,AKT1,ASPM,PLAUR,NUSAP1,DUSP4,CCNF,H2AFV,CDK1,ARF4,STK17A,BCAR3,DNAJC10,UAP1,DNM1L,RND3,AURKA,STK39,PLOD3,NCAPG2,MELK,EHD1 |
| 1.331e-05 | -11.23 | Proteoglycans in cancer | KEGG pathways | ko05205 | 203 | 43 | 6908 | 758 |
CASP3,HSPG2,CD63,IQGAP1,SDC4,TP53,ERBB2,MRAS,ITPR2,SDC1,PRKACA,FZD6,CCND1,TFAP4,IGF1R,PLCG2,PIK3CA,TWIST1,MAPK11,PIK3CD,CTTN,ERBB3,WNT3A,TIAM1,RHOA,AKT1,FZD4,PLAUR,PIK3R1,EZR,ELK1,ITPR3,FZD7,FAS,CTSL,PLCG1,TIMP3,HPSE,ITPR1,ITGAV,FZD5,GAB1,MAPK12 |
| 1.331e-05 | -11.23 | Proteoglycans in cancer | KEGG pathways | hsa05205 | 203 | 43 | 6908 | 758 |
CASP3,HSPG2,CD63,IQGAP1,SDC4,TP53,ERBB2,MRAS,ITPR2,SDC1,PRKACA,FZD6,CCND1,TFAP4,IGF1R,PLCG2,PIK3CA,TWIST1,MAPK11,PIK3CD,CTTN,ERBB3,WNT3A,TIAM1,RHOA,AKT1,FZD4,PLAUR,PIK3R1,EZR,ELK1,ITPR3,FZD7,FAS,CTSL,PLCG1,TIMP3,HPSE,ITPR1,ITGAV,FZD5,GAB1,MAPK12 |
| 1.337e-05 | -11.22 | regulation of immune response | biological process | GO:0050776 | 949 | 137 | 16441 | 1675 |
LAMP1,TAP1,NRG2,PSME1,ITPR2,CACNB4,PDGFB,SPTB,CALM2,PSMD1,RPS6KA2,SHC3,ELMO2,IL6ST,PIK3CA,DUSP10,PIK3CD,SCARA3,SMAGP,RASGRP1,CD55,TNIP1,ITCH,USP18,CASP9,CR2,AGO4,ABR,PLCG1,GPRC5B,LIMK1,NOD2,F2RL1,GAB1,DDX58,LGALS3,THEMIS2,HLA-E,RASA2,HLA-F,CALM3,NCKAP1,TEC,PHLPP1,PIK3AP1,C10orf54,HLA-C,NCAM1,SOCS5,KLK5,MICB,CALM1,ELK1,PSMA4,RASA1,MAPKAPK2,PVRL2,PELI2,PHLPP2,ITPR1,NFKBIA,NLRC5,KLK7,ARPC2,JAK3,IFIH1,TMEM173,SPRED1,IL15,NLRX1,PSME2,RPS6KA1,INPP5D,ERBB2,IL27RA,PRKACA,PDGFA,CDH1,PLCG2,BCL6,CDKN1B,DAB2IP,PDE4D,RASGEF1A,LGMN,FRS3,SIRT1,AKT1,RIPK2,PRKCQ,ITPR3,DUSP4,CD40,SOCS3,IRS2,PTPRJ,JAK1,NRG1,IRF7,SPTBN5,TNRC6C,SELL,PSMD10,BTN3A1,PKN1,FGF19,HLA-A,PTEN,BAX,MAPK11,ERBB3,CNPY3,SYK,PARP9,RASGRF1,PSMB4,PLSCR1,RAPGEF2,NR4A1,PIK3R1,GRIN1,RGCC,YES1,FOS,BCAR1,GPLD1,CTSL,HLA-B,FGFR2,NMI,NR4A3,ERAP1,GRIN2D,PPP2R3C,FZD5,NDFIP1,CD33 |
| 1.343e-05 | -11.22 | regulation of cell growth | biological process | GO:0001558 | 383 | 66 | 16441 | 1675 |
GAS2L1,NF2,FOXM1,RPS6KA1,TP53,ERBB2,PLXNA1,CDKN2C,NOV,CTGF,KIF14,DPYSL2,BCL6,CDKN1B,SEMA3G,CTTN,ACSL4,CDKN2D,SEMA3B,SIRT1,SMARCA2,ING1,AKT1,ITCH,SERTAD3,CDA,PRKCQ,JADE1,ENPP1,PTPRJ,LIMK1,ADIPOR1,EFNA5,NRG1,SEMA6B,IGFBP6,SERPINE2,ARHGEF11,PSMD10,TGFBR1,CRABP2,IL17RB,CXCL16,CYR61,MEGF8,SGK3,ADAM15,SGK1,TNFRSF12A,IGFBP2,WNT3A,OSGIN1,RIMS2,RHOA,FBLN5,MFI2,BCAR1,CDK5R1,RASGRP2,ACVRL1,SEMA4D,CGREF1,SH3BP4,FHL1,SEMA3A,L1CAM |
| 1.347e-05 | -11.21 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 229 | 44 | 17758 | 1761 |
CCNE2,ANXA3,PCOLCE,DEPDC1,FOXM1,CDCA8,FAM198B,CCNB1,FBLN1,PSIP1,ANO1,LMNA,TOP2A,APOBEC3B,RALGPS2,SPIN4,KIF14,AIM1,NEK2,BUB1,IQGAP3,SCARA3,HMMR,ADAMTS2,CENPA,KIF20A,FIGNL1,ASPM,CDC20,PRICKLE1,STMN3,EZR,NUSAP1,LDB2,PRIM1,DPYSL3,AXL,CDCA7L,NMI,MATN2,LTBP2,NCAPG2,CCNB2,NRGN |
| 1.380e-05 | -11.19 | GSE3982_DC_VS_TH2_UP | MSigDB lists | GSE3982_DC_VS_TH2_UP | 187 | 38 | 17758 | 1761 |
MRC2,SORT1,NFKBIE,NQO1,DAP,ABCG2,FTH1,CTSZ,MRAS,FAM198B,PLXNA1,PARM1,EPCAM,PLCG2,MITF,CST3,ADCK2,TACSTD2,ACOX2,FAR2,COQ10B,LITAF,DIAPH2,TNS1,SESN1,ALCAM,CD83,FUCA1,SERPINA1,SLC9A6,SETD3,DTX4,TLE1,PITPNA,RGS14,FZD5,PCSK5,CD33 |
| 1.391e-05 | -11.18 | ZWANG_EGF_INTERVAL_DN | MSigDB lists | ZWANG_EGF_INTERVAL_DN | 194 | 39 | 17758 | 1761 |
KLK10,ARMC7,FBXO2,TESK2,EMP2,ELF3,IRF2BPL,CA2,LLGL2,ARHGEF37,ZFP36,KLF3,DAPK1,FAM63A,KCNS3,DUSP10,DAB2IP,IFIT1,KLF9,HES1,MBP,CITED4,ADCK3,BCL9,PIK3R1,SPATA13,GYLTL1B,TFAP2C,BCAR3,ARHGAP24,RPL12,TIMP3,MATN2,MADD,AGFG2,PLD1,UNC5B,OSR1,REEP4 |
| 1.391e-05 | -11.18 | V$RP58_01 | MSigDB lists | V$RP58_01 | 194 | 39 | 17758 | 1761 |
LTBP1,PCOLCE,SORBS1,NUAK1,TSC22D3,RAB6A,GPSM2,PRKACA,PDGFB,SPTB,SRPX2,TFAP4,FOXP2,DAPK1,ANKRD12,DLG3,BTBD3,CNPY3,RIMS2,ADAMTS2,PCDH1,NR3C1,PRICKLE1,COL7A1,TNS1,LRRC1,TP53INP2,GLT8D2,ABR,XKRX,LRRC42,ONECUT1,PTK7,GRIN2D,KLF5,NR4A2,NRGN,RARG,COL16A1 |
| 1.391e-05 | -11.18 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | 194 | 39 | 17758 | 1761 |
CASP3,MTM1,SORBS1,TXN,LGALS3,S100A11,PTTG1,EFHD2,IL18R1,KCTD9,HLA-A,DAPK2,RRBP1,MDFIC,F2R,SNX10,S100A13,S100A6,PLSCR1,SNTB2,S100A4,LITAF,GGH,DOCK5,RNF19B,ALCAM,CASP4,PRDX4,GALNT3,NUCB1,CARHSP1,ENPP1,IDE,H1F0,NR4A2,ARF6,CCNB2,ACOT7,XDH |
| 1.391e-05 | -11.18 | GSE7764_NKCELL_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_UP | 194 | 39 | 17758 | 1761 |
RUNX2,PPM1J,UBASH3B,ERI2,FAM81A,IL18R1,TRIM68,KCTD9,SYTL2,RNF128,SNX18,PLEKHF1,DAB2IP,C10orf54,PIM1,TMEM37,C8orf58,RAB27B,PTPRE,SPRY2,MGAT5,C9orf9,MMD,PLSCR1,CASP9,PTGER4,RUNX3,ATP1B1,YES1,SP4,DCTN6,KLF12,PLOD2,CDCA7L,ABCB1,CAB39,GEM,FZD5,ARSB |
| 1.391e-05 | -11.18 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | 194 | 39 | 17758 | 1761 |
PINK1,ADD1,CAST,HLA-E,ZCCHC24,CNOT8,INPP5D,ETV5,HEXB,KCTD12,TGOLN2,ITPR2,MGST2,CRABP2,ERP29,PDIA4,METTL7A,IQCE,PLCG2,RUNDC3B,KCNS3,DAPK1,AHCY,CLIP2,ALDH3A2,SMAGP,CORO2A,S100A4,LOXL2,IDH1,SCG2,RAB11FIP2,PRCP,PNPLA6,ZMIZ1,SEMA3A,NRGN,MAPK12,ABCG1 |
| 1.391e-05 | -11.18 | GSE360_DC_VS_MAC_T_GONDII_DN | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_DN | 194 | 39 | 17758 | 1761 |
PINK1,ENO2,HLA-E,TSC22D3,CNOT8,ITGA6,CALM3,KCTD12,CRABP2,MERTK,REPS1,LMNA,PDIA4,CALM2,RPS6KA2,ITGA3,METTL7A,RUNDC3B,SORL1,MANF,NOTCH3,CKAP4,TIMP2,TESK1,S100A4,CALM1,CDA,FOS,ALDH3B1,SCG2,RND3,ZNF165,GDF11,GEM,ZMIZ1,SEMA3A,USF2,LTA4H,ABCG1 |
| 1.393e-05 | -11.18 | negative regulation of apoptotic process | biological process | GO:0043066 | 826 | 122 | 16441 | 1675 |
CASP3,TSC22D3,RPS6KA1,CAST,DNAJC3,PSME2,TP53,ERBB2,PSME1,BCL2L1,CAMK1D,BARD1,STIL,IER3,EPCAM,PSMD1,IL6ST,KIF14,IL31RA,MITF,BCL6,PIK3CA,CDKN1B,TWIST1,CTTN,SLC39A10,LGMN,CDKN2D,F2R,CTH,PLK1,PPIF,SIRT1,RIPK2,AKT1,FIGNL1,ITCH,HTATIP2,GLO1,PRKCQ,SLC25A5,CDK1,POR,ARF4,OPTN,SOCS3,IRS2,MDK,BHLHB9,PLK2,WFS1,AXL,MADD,NOD2,TLE1,HDAC1,IRF7,NRG1,UNC5B,HSPB1,LIFR,PRKAA2,GCLM,PINK1,BMF,CPEB4,LGALS3,ITGA6,SOX9,SLC25A27,PSMD10,TGFBR1,GSTP1,MERTK,LMNA,SIX4,ADORA1,IGF1R,CYR61,PTEN,BMP7,DAPK1,BAX,TFAP2A,TMBIM6,PIM1,MYDGF,ERBB3,CITED2,FAIM,SPRY2,RHOA,PSMB4,PLAUR,GCLC,OXR1,PIK3R1,GRIN1,STRADB,PELI3,IFIT3,PSMA4,MAPK8IP1,G2E3,RASA1,FAS,FGFR2,SEMA4D,SCG2,DHRS2,NFKBIA,NR4A3,AURKA,ARRB1,NR4A2,ITGAV,SOX8,OSR1,JAK3,RARG,HIPK3,IFI6 |
| 1.395e-05 | -11.18 | MODULE_239 | MSigDB lists | MODULE_239 | 114 | 27 | 17758 | 1761 |
SYPL1,FADS2,B3GNT2,TBC1D1,TACC1,DNAJC3,LPGAT1,PIK3R1,GLO1,RAB6A,BCAP31,CHPF,PDIA4,APLP2,IDE,PPP2R5A,TWSG1,IL6ST,DLG1,PCYOX1,CAB39,ADIPOR1,MANF,C1orf43,LRP11,OCLN,CCDC88A |
| 1.414e-05 | -11.17 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 448 | 73 | 17758 | 1761 |
UNKL,ST14,VANGL1,PDIA5,ARFGEF1,CYP39A1,REPS1,APPBP2,CDS1,WEE1,CABP1,FOSB,MYT1,CTDSP2,DVL2,FRS3,THRB,CLCN3,PTPN9,PANK1,PTGER4,GALNT7,FZD7,EDNRA,NGFRAP1,PLK2,LIMK1,RAB11FIP1,CAB39,LIFR,ABCA1,NXT2,RMND5A,CPEB4,CIT,ZCCHC24,MIER3,TGFBR1,NRP2,NEO1,AKIRIN1,FOXP2,GNS,CCDC92,E2F7,LYPD3,GATA2,FLRT3,RIMS3,NEK2,WNT3A,SPRY2,ATP2B1,MDFI,MMD,ZKSCAN2,PPARA,LITAF,FAM133B,DCP2,GALNT3,PLEKHH2,RND3,CSNK1G1,PHLPP2,CSF1,MFSD2A,PGM2L1,CDK18,SH3BGRL2,STK39,AFAP1,PKIA |
| 1.417e-05 | -11.16 | LGALS9 (lectin, galactoside-binding, soluble, 9) | protein interactions | 3965 | 72 | 21 | 16036 | 1726 |
ENPP4,CLCN3,MRC2,LGALS3,CD63,OSTM1,PBK,PDIA3,PLXNA1,PTGFRN,ALCAM,FBLN1,DAG1,CD109,SLC6A6,PTPRJ,SLC9A6,SORL1,PDIA6,SLC12A2,IGSF3 |
| 1.417e-05 | -11.16 | other | COSMIC cancer mutations | other | 15619 | 1597 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,DPP8,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,RNF224,TPRN,NQO1,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,PIK3CA,IRF2,SNX16,MARCH2,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ADAM15,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,LPIN3,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.426e-05 | -11.16 | apical junction complex | cellular component | GO:0043296 | 126 | 29 | 17570 | 1756 |
DDX58,AMOTL2,CAMSAP3,SORBS1,RHOA,FRMD4A,CRB3,BVES,FRMD6,RAPGEF2,TGFBR1,F11R,MPP5,EPCAM,CCND1,CDH1,TJP3,SHROOM3,PVRL2,TBCD,RAP2C,DLG1,CLDN4,POF1B,EPB41L4B,DLG3,FZD5,SHROOM2,OCLN |
| 1.429e-05 | -11.16 | RhoGEF | pfam domains | PF00621 | 70 | 20 | 16629 | 1696 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ARHGEF9,ARHGEF4,FGD1,FARP2 |
| 1.432e-05 | -11.15 | positive regulation of apoptotic process | biological process | GO:0043065 | 561 | 89 | 16441 | 1675 |
CASP3,NQO1,INPP5D,RET,TP53,COL18A1,BCL2L1,CAMK1D,AIFM2,BARD1,PHLDA1,BCAP31,ARHGEF16,RPS6KA2,CTGF,SIVA1,ALDH1A3,BCL6,CDKN1B,DAB2IP,EGLN3,TIAM1,F2R,CYP1B1,SIRT1,PPIF,RIPK2,AKT1,ACVR1C,CASP9,SLC11A2,CD40,PRKRA,SAV1,STK17B,ABR,DNM1L,CDK19,NGFRAP1,KLF11,FGD1,BIN1,ARHGEF3,PINK1,BMF,NKX3-1,ARHGEF11,DAP,ITGA6,PDIA3,TGFBR1,AES,ADAMTSL4,TOP2A,TFAP4,CARD8,CYR61,CTSC,PTEN,BMP7,TFAP2A,BAX,MAP3K9,DAPK1,PLEKHF1,BUB1,TNFRSF12A,WNT3A,OSGIN1,RHOA,RAPGEF2,PLAUR,ANO6,GRIN1,RGCC,SCRIB,CDK5R1,FAS,GPLD1,STK17A,NR4A3,ARRB1,GPER1,MAP3K5,ARHGEF9,RARG,MELK,ARHGEF4,XDH |
| 1.467e-05 | -11.13 | DITTMER_PTHLH_TARGETS_UP | MSigDB lists | DITTMER_PTHLH_TARGETS_UP | 108 | 26 | 17758 | 1761 |
CPD,LAMP1,LTBP1,PDGFC,TNIP1,PRSS23,GALNT7,CDK1,RANBP9,ATP10D,RHEB,ARF4,SGPL1,NUCB1,ATP1A1,TIMP3,H1F0,COL6A1,DLG1,STK39,KLF9,UBE2C,F2RL1,ATP2B1,GPX4,CKS2 |
| 1.472e-05 | -11.13 | hemostasis | biological process | GO:0007599 | 530 | 85 | 16441 | 1675 |
PLA2G4A,MYL9,PAPSS2,INPP5D,TP53,F11R,ITPR2,PRKACA,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,LMAN1,F2R,RASGRP1,LAMP2,ENPP4,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,HABP4,DGKQ,SELL,KIF23,CALM3,FBLN1,MERTK,FZD6,SIRPA,ITGA3,GATA2,CD9,PRKG1,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,L1CAM,EHD1,DOCK9 |
| 1.479e-05 | -11.12 | SCN4A (sodium channel, voltage gated, type IV alpha subunit) | protein interactions | 6329 | 10 | 7 | 16036 | 1726 |
SNTA1,ERBB2IP,DLG3,SNTB1,SNTB2,CALM1,DLG1 |
| 1.482e-05 | -11.12 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 601 | 94 | 16441 | 1675 |
EMX1,GRHL2,ADD1,HSPG2,HOXB7,EPAS1,ST14,TP53,OSR2,BCL2L1,CCNB1,PRKACA,STIL,PDGFB,RCN1,CYP1A1,LMO4,DLG1,PLK4,TWIST1,ECE1,ACSL4,ZBTB18,DVL2,SULF2,SPEF2,AKT1,TFAP2C,ICMT,ZFAND5,EDNRA,ARHGAP35,SOCS3,HS6ST1,PLCG1,SHROOM3,PTK7,HOXA9,TRAF3IP1,TANC2,GAB1,E2F8,COBL,MAFF,PCSK5,GRN,CTHRC1,RUNX2,NKX3-1,CDKN1C,SDC4,RAB23,TGFBR1,NCKAP1,HOXB2,SIX4,PPP2R3A,FZD6,ELF3,MECOM,E2F7,CYR61,GATA2,BMP7,MEGF8,FUT8,NEK2,TFAP2A,WNT3A,MDFI,EPB41L5,TGIF1,HES1,SALL4,UBE2A,PRICKLE1,VEZT,SCRIB,G2E3,GNAS,NCOA3,FGFR2,ACVRL1,SPINT2,TBX18,PLOD3,FZD5,ZMIZ1,SOX8,OSR1,NCAPG2,CCNB2,RARG,EGLN1 |
| 1.492e-05 | -11.11 | positive regulation of GTPase activity | biological process | GO:0043547 | 499 | 81 | 16441 | 1675 |
ARHGAP11A,RALBP1,IQGAP1,ARFGEF1,RGS20,ERBB2,F11R,DENND2D,ARHGEF16,EPS8L2,ARHGEF10L,SIPA1L2,ST5,ACAP2,SH3BP1,ARHGEF37,RGS3,RP2,RASGEF1A,TIAM1,RASGRP1,DOCK4,ARHGDIB,CD40,DOCK5,ABR,ARHGEF26,ARHGAP35,PLEKHG6,ARHGEF19,CORO1C,MADD,SIPA1L1,PLEKHG1,AGFG2,RGS14,RAP1GAP,FGD1,DENND5B,ARFGEF3,ARHGEF3,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,ITGA6,SBF1,ARHGEF40,RALGPS2,SNX18,LLGL2,RINL,FAM13B,RANBP1,TBCD,IQGAP3,ALS2CL,FARP2,RASGRF1,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,SPATA13,SCRIB,EPHA1,GRTP1,RASA1,RASGRP2,GNAS,ARHGAP24,BCAR3,SEMA4D,FGD6,ARRB1,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4,DOCK9 |
| 1.495e-05 | -11.11 | REACTOME_IMMUNE_SYSTEM | MSigDB lists | REACTOME_IMMUNE_SYSTEM | 891 | 127 | 17758 | 1761 |
SIGIRR,TXN,NLRX1,PSME2,RPS6KA1,TAP1,FBXO2,RNF182,IL18,PSME1,CD274,BCL2L1,ITPR2,PJA2,PRKACA,SH3KBP1,CALM2,RNF220,AP1M2,PSMD1,RPS6KA2,SP100,CDH1,STIM1,IL6ST,PLCG2,PIK3CA,CDKN1B,IRF2,IFIT1,PIK3CD,OAS3,LGMN,RASGRP1,MAP3K3,MX1,SEC23A,CD55,SEC61B,RIPK2,AKT1,USP18,CASP9,CDC20,PRKCQ,DUSP4,CD40,ITPR3,ASB13,CDK1,CASP4,SOCS3,IRS2,TRIM9,PLCG1,JAK1,PPP2R5A,DDOST,NOD2,IRF7,RAP1GAP,MAPK12,DDX58,MRC2,NFKBIE,LGALS3,KLHL13,HLA-F,ASB9,KIF23,PSMD10,SELL,PDIA3,HERC5,CALM3,FBXO6,PHLPP1,HLA-A,DTX3L,KIF5B,UBE2Q2,PTEN,PIK3AP1,CTSC,KLC3,UBE2J1,PRKG1,TRIM21,WWP1,MAPK11,HLA-C,NCAM1,CNPY3,ULBP2,NUP85,SYK,PSMB4,KIF20A,IFITM3,NR4A1,PIK3R1,CALM1,UBE2A,PELI3,YES1,IFIT3,ELK1,KIF11,FOS,PSMA4,RASGRP2,MAPKAPK2,DCTN6,HLA-B,PVRL2,PELI2,NFKBIA,NLRC5,ERAP1,CTSA,ITGAV,FBXO27,ICOSLG,UBE2C,IFIH1,JAK3,IFI6 |
| 1.499e-05 | -11.11 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | MSigDB lists | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | 72 | 20 | 17758 | 1761 |
DDX58,CCNE2,MX1,IGFBP6,ABCG2,PTGER4,HERC5,SAMD9,IFIT3,HERC6,CRISPLD2,NOV,TIMP3,HPSE,FAM46A,ALDH1A3,SORL1,IFIT1,SEMA3A,IFIH1 |
| 1.521e-05 | -11.09 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 147 | 32 | 17758 | 1761 |
LASP1,TM2D2,AVPI1,PAPSS2,DAP,ASAH1,PKP2,FAM101B,WWP2,ATP6V0B,CTGF,CD9,FXYD5,TRAM1,SNX10,S100A13,RBMS2,ABCC1,RHOA,ALDH2,PQLC3,PRSS23,NFE2L1,UTRN,C3orf58,CARHSP1,TIMP3,SERPINB6,FHL1,TMEM159,TOB1,ACOT7 |
| 1.521e-05 | -11.09 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 147 | 32 | 17758 | 1761 |
PRSS8,RUNX2,S100A11,PTTG1,ERI2,C5orf30,MORC4,NUF2,NENF,DDR1,BEX2,CYP39A1,SIRPA,IER3,PDGFA,CCND1,BTG3,XYLT2,BMP7,AKR1B1,TAGLN2,ACSL4,PTPRE,TLE6,WBP5,HMMR,CD40,TCEAL8,DNAJC10,ABCB1,ANXA9,FGD1 |
| 1.550e-05 | -11.07 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | 181 | 37 | 17758 | 1761 |
DDX58,PARP12,IL15,ARHGEF11,TAP1,HERC5,SAMD9,CD274,HERC6,HPCAL4,LGALS3BP,DTX3L,FAM46A,GRHL1,TRIM21,IFIT1,OAS3,MYBL1,GAD1,ETV7,APOBEC3G,PARP9,MX1,AMOTL2,PLSCR1,IFITM3,USP18,IFIT3,ZNF618,SEMA4D,C19orf66,SECTM1,NLRC5,IRF7,CMPK2,IFIH1,IFI6 |
| 1.550e-05 | -11.07 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | 181 | 37 | 17758 | 1761 |
SORT1,PINK1,SPC25,IGFBP6,CDKN1C,ZCCHC24,DNAJC3,ITGA6,PTTG1,SDC1,PPP2R3A,PDIA4,TOP2A,MITF,RRBP1,NEK2,MANF,FAR2,LMAN1,ALDH3A2,KDELR1,CTH,SSH3,SEC61B,TIMP2,KIF20A,C3orf52,CDC20,CBX6,PRKAR2B,CDK1,OPTN,DOLPP1,CSTF2,UBE2C,CCNB2,MELK |
| 1.551e-05 | -11.07 | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | 121 | 28 | 17758 | 1761 |
PSMB4,NFKBIE,AKT1,NR4A1,PSME2,CASP9,CALM1,PIK3R1,PSMD10,CALM3,PSME1,ITPR2,PHLPP1,ITPR3,PSMA4,SH3KBP1,CALM2,PLCG1,PSMD1,PTEN,PIK3AP1,STIM1,NFKBIA,PLCG2,CDKN1B,PIK3CD,SYK,RASGRP1 |
| 1.575e-05 | -11.06 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | 195 | 39 | 17758 | 1761 |
GRN,LGALS3,S100A11,HEXB,ASAH1,KCTD12,ARHGEF40,SIRPA,ARHGEF10L,GNS,APLP2,ATP6V0B,TNS3,SLC16A6,BCL6,DAPK1,MTMR11,PTPRE,SNX10,SYK,CCDC88A,CKAP4,GCA,MCTP1,TIMP2,PLSCR1,DIAPH2,NPC2,PCTP,ZFAND5,ADRBK2,STX3,MID1IP1,RBM47,CORO1C,NOD2,ZMIZ1,SLC27A3,CD33 |
| 1.591e-05 | -11.05 | endosome membrane | cellular component | GO:0010008 | 392 | 66 | 17570 | 1756 |
LAMP1,EPHA4,RET,ERBB2,MVB12B,ZFYVE9,SLC9A7,ZFYVE16,RAB15,ATP6V0B,ACAP2,WDR44,STEAP2,ABCA2,SNX16,ECE1,MARCH2,RAB27B,SNX10,TMEM9,LAMP2,CLCN3,SLC11A2,KIF13A,WIPI1,SLC9A6,IRF7,ARF6,STARD3NL,PACSIN2,GOLIM4,SORT1,GGA1,CD63,HLA-F,HLA-E,TMEM55B,ATP9A,RAB23,FAM21C,VPS26A,PARM1,HLA-A,MARCH8,SNX18,ZNRF2,KIAA0319,PLEKHF1,HLA-C,WNT3A,PIKFYVE,TPCN1,SUN2,MMD,IFITM3,ANTXR1,CPTP,STEAP1,HLA-B,RAB11FIP2,RAP2C,PLD1,PLIN3,FZD5,NDFIP1,EHD1 |
| 1.598e-05 | -11.04 | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES | MSigDB lists | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES | 14 | 8 | 17758 | 1761 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 1.599e-05 | -11.04 | human chrXq22 | chromosome location | human chrXq22 | 18 | 8 | 26250 | 1887 |
FRMPD3,HNRNPH2,TSPAN6,COL4A5,MORF4L2,GLA,DRP2,BEX2 |
| 1.603e-05 | -11.04 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | 61 | 18 | 17758 | 1761 |
ARHGEF3,GCLC,PTTG1,TCF7,IFIT3,IDH1,PHLDA1,EDNRA,CDH1,SPINT2,BCL6,CD9,DAPK1,CLDN4,KLF5,ERBB3,RAB27B,SLC12A2 |
| 1.610e-05 | -11.04 | negative regulation of protein kinase activity | biological process | GO:0006469 | 204 | 41 | 16441 | 1675 |
CASP3,SPRED1,NF2,CDKN1C,UBASH3B,DNAJC3,PKN1,TRIB2,GSTP1,TFAP4,CDKN2C,IGF1R,PTEN,BMP7,RGS3,DUSP10,CDKN1B,SORL1,DAB2IP,CDKN2D,SPRY2,SOCS5,CHP1,PLK1,SIRT1,AKT1,PRKAR2B,EPHA1,DUSP4,MAPK8IP1,SOCS3,CDK5RAP1,PRKAG2,PTPRJ,STK38,CORO1C,RGS14,UBE2C,HSPB1,HIPK3,PKIA |
| 1.638e-05 | -11.02 | response to insulin | biological process | GO:0032868 | 408 | 69 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,PSME2,NRG2,ERBB2,PSME1,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,SESN3,PSMD1,SHC3,PIK3CA,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,AKT1,ACVR1C,PRKCQ,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,GAB1,RRAGD,PRKAA2,SORT1,RASA2,PSMD10,CALM3,FGF19,HDAC9,IGF1R,ERBB3,NCAM1,MYO5A,GCNT1,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,BCAR1,PSMA4,RASA1,GPLD1,PRKAG2,FGFR2,GRIN2D,TBC1D4,JAK3,CPEB2 |
| 1.656e-05 | -11.01 | DELACROIX_RARG_BOUND_MEF | MSigDB lists | DELACROIX_RARG_BOUND_MEF | 357 | 61 | 17758 | 1761 |
PRSS8,LTBP1,NUDT6,SLC25A24,PCOLCE,AVPI1,NDUFA4,PRSS22,FTH1,GDF15,F11R,CRABP2,PKN1,DHRS3,CARD10,LTBP3,EPS8L2,H1FX,IRF2BPL,CCND1,KIF5B,ADD3,ST5,CTGF,SH3BP1,ZNRF2,DOK4,OSBPL3,AOX1,NEK2,SGK1,TNFRSF12A,TAGLN2,CTTN,CDKN2D,ALS2CL,SUN2,SNTB2,COQ10B,S100A4,SAT1,FURIN,LOXL2,DUSP4,PRX,DPYSL3,GABARAPL1,ARHGEF19,TIMP3,SLC25A4,GDE1,FGFR2,RND3,PEX2,RHOBTB2,ANXA9,HMGA1,OSR1,NDFIP1,UBE2C,RARG |
| 1.657e-05 | -11.01 | protein complex binding | molecular function | GO:0032403 | 907 | 131 | 16491 | 1673 |
CASP3,ADD1,HDAC6,PDGFB,SPTB,EPCAM,CTGF,STIM1,NPNT,DPYSL2,MYH14,TLN2,PLK1,KIFC2,EZR,KIF13A,ENPP1,MAP2,PLK2,TRAF3IP1,HDAC1,LASP1,MRC2,LGALS3,PEX6,ITGA6,DNAJB2,PDCL,KIF23,NDUFA4,NCKAP1,FBLN1,ITGA3,IGF1R,CYR61,KIF13B,CCDC88A,DPYSL5,KIF20A,CORO2A,ANTXR1,GNA11,PTPRF,GNAS,AP1AR,PLPP3,NFKBIA,FAM83D,CABIN1,NDE1,ARPC2,SHROOM2,COL16A1,GAS2L1,LZTFL1,MTM1,SORBS1,NF2,IQGAP1,THRA,PKP2,EMP2,APC2,DDR1,PRKACA,BCAP31,CCND1,PDGFA,NOV,KIF14,DOK4,REEP1,CDKN1B,DAB2IP,ESPN,CHP1,FRS3,SIRT1,CAMSAP3,TIMP2,CAPN6,COG2,SYNE2,UTRN,KIF1C,NUSAP1,RAB38,ERBB2IP,ATP1B1,KCTD2,DAG1,GABARAPL1,IRS2,SHROOM3,CORO1C,TRIOBP,SPTBN5,MLKL,RGS14,REEP4,PCOLCE,ADGRG1,HMGN3,HLA-A,KIF5B,ADORA1,PTEN,KLC3,BAX,CD9,ADAM15,CLIP2,SYK,CRTAP,SUN2,FBLN5,LCA5,FMN1,AMFR,SYBU,PIK3R1,PPARA,AIF1L,KIF11,CDK5RAP1,CTSL,ACVRL1,CTSV,ARRB1,CENPE,L1CAM |
| 1.700e-05 | -10.98 | EF-hand-dom_pair | interpro domains | IPR011992 | 260 | 48 | 18293 | 1814 |
MYL9,SLC25A24,REPS2,S100A11,SLC25A13,CALB2,CALM3,EFHD2,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,PLS3,CALM2,RCN1,CABP1,PLCB2,DGKG,S100A13,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,STAT4,S100A4,CALM1,UTRN,AIF1L,MCFD2,MYL12A,NIN,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,CGREF1,NKD1,S100A5,EFCAB14,PPP2R3C,DRP2,CAPN1,EHD1 |
| 1.734e-05 | -10.96 | CDK1 (cyclin-dependent kinase 1) | protein interactions | 983 | 234 | 47 | 16036 | 1726 |
CDK17,RUNX2,REPS2,DLGAP5,CDKN1C,FOXM1,PTTG1,TP53,FBXO6,CCNB1,BARD1,LMNA,TOP2A,CCND1,WEE1,APLP2,CALD1,CDKN1B,BUB1,MYT1,CKS2,SIRT1,MBP,PBK,CDC20,UBE2A,RGCC,CDCA2,PKMYT1,CCNF,KIF11,CDK1,DCTN6,H1F0,ITPR1,CDCA5,RYK,TLE1,MLKL,HMGA1,NDE1,JAK3,HSPB1,CCNB2,RAP1GAP,ESPL1,LZTS1 |
| 1.742e-05 | -10.96 | cell-substrate adhesion | biological process | GO:0031589 | 164 | 35 | 16441 | 1675 |
BCAM,SORBS1,CD63,BVES,ITGA6,TESK2,DDR1,EMP2,MERTK,EPDR1,ITGA3,MUC4,ITGB8,CTGF,NPNT,LYPD3,KIF14,ADAM15,TNFRSF12A,CTTN,TIAM1,EPB41L5,SGCE,RHOA,FBLN5,FZD4,EPHA1,ANTXR1,DAG1,FZD7,HPSE,COL13A1,AXL,ITGA7,ITGAV |
| 1.751e-05 | -10.95 | embryonic morphogenesis | biological process | GO:0048598 | 556 | 88 | 16441 | 1675 |
NF2,GRHL2,HSPG2,HOXB7,ST14,RET,TP53,OSR2,PRKACA,STIL,SETDB2,IMPAD1,DACT1,LMO4,ELF5,ALDH1A3,DLG1,TWIST1,ECE1,DVL2,SPEF2,ARFRP1,DUSP4,PRKRA,COL12A1,ABR,ARHGAP35,SOCS3,SHROOM3,PTK7,HOXA9,LRIG1,TRAF3IP1,HDAC1,COBL,CTHRC1,RUNX2,TNRC6C,CDKN1C,LRP4,SDC4,SOX9,RAB23,TGFBR1,NCKAP1,CRABP2,HOXB2,SIX4,FZD6,MECOM,ITGA3,CYR61,GATA2,FLRT3,MEGF8,FRAS1,BMP7,COL6A1,BAX,TFAP2A,WNT3A,SPRY2,MDFI,EPB41L5,CYP26B1,HES1,TGIF1,SALL4,PRICKLE1,COL7A1,SCRIB,NPHP3,GNAS,MMP15,NCOA3,ETS2,TWSG1,FGFR2,PLPP3,ITGA7,TBX18,SPINT2,NR4A3,ITGAV,SOX8,OSR1,FZD5,RARG |
| 1.753e-05 | -10.95 | SH3 | prosite domains | PS50002 | 201 | 41 | 11866 | 1235 |
BIN1,LASP1,SORBS1,PACSIN2,TRIP10,RUSC2,UBASH3B,EPS8,MPP5,TEC,CACNB4,ARHGEF16,SH3KBP1,EPS8L2,ARHGEF37,SNX18,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,PLCG1,ARHGEF19,TJP3,SH3BP4,ARHGEF9,RUSC1,ARHGEF4 |
| 1.764e-05 | -10.95 | RHODES_UNDIFFERENTIATED_CANCER | MSigDB lists | RHODES_UNDIFFERENTIATED_CANCER | 67 | 19 | 17758 | 1761 |
GCLM,CENPA,SEC61B,DLGAP5,FOXM1,CDC20,TAP1,MYBL2,KIF23,GGH,GPSM2,CCNB1,CDK1,PRDX4,TOP2A,KIF14,UBE2C,MELK,CKS2 |
| 1.765e-05 | -10.94 | tissue morphogenesis | biological process | GO:0048729 | 564 | 89 | 16441 | 1675 |
NF2,GRHL2,LGR4,ST14,EPHA4,RET,PKP2,MPP5,PLXNA1,PRKACA,DDR1,STIL,SETDB2,ARTN,NPNT,LMO4,ALDH1A3,DLG1,TWIST1,TACSTD2,DLG3,ETV4,DVL2,EZR,TFAP2C,DAG1,EDNRA,ARHGAP35,SOCS3,SHROOM3,PTK7,NRG1,COBL,CTHRC1,NKX3-1,SDC4,SOX9,RAB23,CTSZ,NCKAP1,HOXB2,SIX4,FZD6,CTNNBIP1,CA2,ITGA3,IGF1R,CYR61,FLRT3,MEGF8,FRAS1,BMP7,FJX1,BAX,TFAP2A,WNT3A,SLC12A2,SPRY2,GCNT1,EPB41L5,HES1,TGIF1,RHOA,FMN1,SALL4,PRICKLE1,SCRIB,NPHP3,FOXL1,ARHGAP24,NCOA3,FAT4,TWSG1,ACVRL1,FGFR2,CSF1,TBX18,CTSV,SPINT2,NR4A3,HOXB13,SOX8,OSR1,FZD5,PLOD3,SEMA3A,RARG,ADAMTS16,EGLN1 |
| 1.767e-05 | -10.94 | adherens junction | cellular component | GO:0005912 | 471 | 76 | 17570 | 1756 |
LMO7,SORBS1,KIAA1462,NF2,ADD1,HSPG2,IQGAP1,PKP2,SDC1,SH3KBP1,CDH1,DLG1,IRF2,CDH3,DIXDC1,CTTN,TLN2,SMAGP,CHP1,CAMSAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,JAK1,SHROOM3,CORO1C,PTK7,LIMK1,TRIOBP,ARF6,HSPB1,CAPN1,CD99,FBLIM1,LASP1,MRC2,PACSIN2,ITGA6,SDC4,KIF23,PDIA3,NCKAP1,TNS3,ITGA3,FLRT3,TBCD,CD9,ADAM15,EPB41L5,PVRL4,RHOA,FMN1,PLAUR,SCRIB,VEZT,YES1,AIF1L,SNTB1,BCAR1,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,PLPP3,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,SHROOM2,L1CAM,AFAP1 |
| 1.777e-05 | -10.94 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 38 | 17758 | 1761 |
PACSIN2,NLRX1,ASAH1,FTH1,SAMD9,SNN,KBTBD11,ARHGEF40,IL18R1,CMTM6,APLP2,TYMP,PTEN,BCL6,ACSL4,PTPRE,CKAP4,MYO5A,MAP3K3,ORAI2,CD55,MBP,TACC1,CDA,HMG20B,FOS,GABARAPL1,FUCA1,SWAP70,ANKRD6,PELI2,NMI,PNPLA6,ZDHHC7,FGD6,ZMIZ1,JARID2,EHD1 |
| 1.777e-05 | -10.94 | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 189 | 38 | 17758 | 1761 |
LTBP1,GCLM,SLC25A24,DEPDC1,ZCCHC24,NDC80,ERI2,COL4A5,PLXNA1,CENPN,TEAD3,PDGFA,SS18,GATA2,IMPAD1,TPST1,TAGLN2,FAIM,BTBD3,NAGA,CRTAP,FAH,GCNT1,ALDH2,COL6A2,MMD,RAPGEF2,MGAT4B,LDB2,ICMT,CRISPLD2,DPYSL3,EDNRA,DNAJC10,FAM64A,ZDHHC7,YOD1,ATP1B3 |
| 1.781e-05 | -10.94 | MEMBRANE_FRACTION | MSigDB lists | MEMBRANE_FRACTION | 335 | 58 | 17758 | 1761 |
LAMP1,IL15,TSPAN15,SLC1A3,SLC7A2,MGST2,POMGNT1,KREMEN1,CYP39A1,NRP2,SYTL2,B4GALNT1,SLC16A6,A4GALT,STEAP2,FUT1,TPST1,ATP8B1,CD70,TSPAN13,ECE1,OAS3,SLC12A2,SLC16A5,RASGRP1,CKAP4,KDELR1,ABCC1,LAMP2,CPD,PPIF,FADS2,MCTP1,MMD,MPP1,SNTB2,AMFR,RC3H2,UTRN,ARFRP1,PKMYT1,ICMT,BCAR1,DAG1,GALNT3,HLA-B,SCARB2,ATP1A1,FAAH,WFS1,SLC9A6,SLC4A3,ABCB1,ARRB1,ARF6,RAP1GAP,PTGES,ABCA1 |
| 1.785e-05 | -10.93 | Corticotropin-releasing hormone | WikiPathways | WP2355 | 90 | 25 | 4455 | 516 |
PRKAA2,CASP3,RHOA,AKT1,NR4A1,CASP9,PRKCQ,IL18,GRK6,ELK1,FOS,ADRBK2,GNA11,GNAS,PLCG1,GNB5,PLCG2,NFKBIA,FOSB,TFAP2A,ARRB1,NR4A2,ECE1,MAP3K5,NCOA2 |
| 1.807e-05 | -10.92 | YAGI_AML_WITH_T_8_21_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_T_8_21_TRANSLOCATION | 358 | 61 | 17758 | 1761 |
CD99,SLC35D2,BCAM,UGP2,SERPINE2,RALBP1,RPS6KA1,CUL4B,GNE,CACNA2D2,AES,TGFBR1,IL27RA,TGOLN2,BCL2L1,DDR1,TSPAN7,RCN1,TFAP4,CDKN2C,CCND1,EPCAM,NOV,STIM1,DPYSL2,SORL1,VAT1,TMBIM6,RFX5,MANF,CDKN2D,ABCC1,SOCS5,ORAI2,TGIF1,FBLN5,S100A4,PIK3R1,FURIN,AK4,GLO1,BLVRA,ABR,NFIX,SOCS3,MDK,GNAS,PLCG1,SWAP70,ALDH5A1,AGPAT2,ACADSB,JAK1,GDE1,SIPA1L1,ITPR1,HDAC1,AURKA,FZD5,JAK3,ESPL1 |
| 1.815e-05 | -10.92 | BORLAK_LIVER_CANCER_EGF_UP | MSigDB lists | BORLAK_LIVER_CANCER_EGF_UP | 56 | 17 | 17758 | 1761 |
TGIF1,PLSCR1,S100A11,CD63,CCNB1,FOS,ALCAM,DDR1,CDK1,ELF3,CCND1,PDGFA,BTG3,CA2,ETS2,SERPINB6,WBP5 |
| 1.824e-05 | -10.91 | negative regulation of protein serine/threonine kinase activity | biological process | GO:0071901 | 119 | 28 | 16441 | 1675 |
PLK1,SIRT1,CASP3,SPRED1,CDKN1C,PRKAR2B,DUSP4,GSTP1,CDK5RAP1,CDKN2C,TFAP4,PTPRJ,PRKAG2,PTEN,BMP7,RGS3,STK38,DUSP10,SORL1,CDKN1B,DAB2IP,RGS14,CDKN2D,UBE2C,HSPB1,HIPK3,SPRY2,PKIA |
| 1.868e-05 | -10.89 | urogenital system development | biological process | GO:0001655 | 305 | 55 | 16441 | 1675 |
NKX3-1,CDKN1C,LGR4,THRA,IQGAP1,ITGA6,LRP4,RET,EPHA4,SOX9,SDC4,TGFBR1,OSR2,SDC1,PDGFB,SIX4,SGPL1,MECOM,CTNNBIP1,EPCAM,CA2,ITGA3,IGF1R,PTEN,NPNT,GATA2,BMP7,FRAS1,DLG1,TFAP2A,BAX,AKR1B1,TACSTD2,NOTCH3,TIPARP,SULF2,GCNT1,HES1,FMN1,AMER1,PYGO1,NPHP3,FAT4,FGFR2,WFS1,TBX18,OVOL1,HOXB13,GDF11,OSR1,SOX8,AHR,RARG,PCSK5,ADAMTS16 |
| 1.889e-05 | -10.88 | DH_2 | prosite domains | PS50010 | 70 | 20 | 11866 | 1235 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ARHGEF9,ARHGEF4,FGD1,FARP2 |
| 1.892e-05 | -10.88 | YIH_RESPONSE_TO_ARSENITE_C1 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C1 | 22 | 10 | 17758 | 1761 |
TOP2A,HSF2,ZFP36,NAT1,MYBL2,PIK3CA,CCNB1,RASA1,FAS,SGPL1 |
| 1.898e-05 | -10.87 | REACTOME_SIGNALING_BY_ERBB2 | MSigDB lists | REACTOME_SIGNALING_BY_ERBB2 | 97 | 24 | 17758 | 1761 |
AKT1,NR4A1,CALM1,CASP9,PIK3R1,CALM3,NRG2,ERBB2,PRKAR2B,YES1,ITPR2,ITPR3,PHLPP1,PRKACA,CDK1,CALM2,PLCG1,ADRBK1,PTEN,PIK3CA,CDKN1B,NRG1,ERBB3,GAB1 |
| 1.936e-05 | -10.85 | GTGGGTGK_UNKNOWN | MSigDB lists | GTGGGTGK_UNKNOWN | 276 | 50 | 17758 | 1761 |
SORBS1,RUNX2,IGFBP6,CDH22,THRA,UBASH3B,ARFGEF1,CALM3,TGFBR1,PDGFB,SPTB,KREMEN1,BCAP31,CALM2,TFAP4,ADD3,FUT2,ZCCHC12,MITF,CDKN1B,TWIST1,ABCD1,ACSL4,SLC12A2,SCYL3,SEMA3B,SIRT1,ATL1,CAPN6,ACVR1C,NR3C1,DEPDC4,LYRM1,CALM1,PANK1,EPHA1,SP4,PRX,RASA1,PGF,PITX2,KLF12,TMEM54,ITPR1,TRAF3IP1,NR4A3,OTUB2,ARPC2,NRGN,KLF7 |
| 1.960e-05 | -10.84 | EZR (ezrin) | protein interactions | 7430 | 144 | 33 | 16036 | 1726 |
ENO2,NF2,GNPDA1,IQGAP1,PTTG1,DGKQ,HEXB,SELL,ISYNA1,FBXO6,OAT,PLS3,RCN1,CDH1,DLG1,AKR1B1,WWP1,TAGLN2,SYK,SCYL3,GPX4,RHOA,PIK3R1,EIF5A2,EZR,ARHGDIB,PRX,FAS,HLA-B,PHLPP2,AURKA,ARF6,L1CAM |
| 1.980e-05 | -10.83 | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 176 | 36 | 17758 | 1761 |
MRC2,LGALS3,TSPAN15,INPP5D,EPHA4,EPS8,TMX4,PTTG1,MGST2,LMNA,GNS,CD109,CXCL16,UBE2T,SH3BP1,PHTF1,PIKFYVE,C12orf75,SCYL3,TRIM62,PGM1,ELK3,ANO6,RUNX3,F12,CCNF,TXNDC11,FRMD4B,MMP17,PHLPP2,SETD3,NOD2,PLEKHG1,PITPNA,DONSON,E2F8 |
| 2.002e-05 | -10.82 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 183 | 37 | 17758 | 1761 |
SERPINE2,THRA,INPP5D,CD82,FBLN1,WWP2,FAM111A,FRY,MKRN3,RPL39,ALDH1A3,AIM1,TFAP2A,FAM102A,RFX5,PIK3CD,SCARA3,TSPAN1,GCA,RASGRF1,ING1,CXorf57,UTRN,CR2,KIF13A,TCF7,LEPR,ENDOD1,BANK1,SLC4A4,CSF1,DCK,DTX4,TRAF5,CBX7,PKIA,KLF7 |
| 2.011e-05 | -10.81 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | 51 | 16 | 17758 | 1761 |
GRN,LAMP1,PAPSS2,SLC39A8,SAT1,F11R,IFIT3,IDH1,FUCA1,SGK1,RPN2,LGMN,TRAM1,ATP2B1,GM2A,TRAK2 |
| 2.012e-05 | -10.81 | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | 197 | 39 | 17758 | 1761 |
BIN1,ARHGEF3,ATP9A,ARL4C,MERTK,FAM46C,TNFSF9,NCS1,LMNA,M6PR,NPNT,TACSTD2,TIPARP,TGIF1,TNIP1,USP18,STAT4,PIK3R1,PTGER4,LITAF,FNDC3A,RNF19B,POR,STX3,ARF4,GABARAPL1,CD83,SLC6A6,TWSG1,NFKBIA,NR4A3,NR4A2,SERPINI1,MDH1,ITGAV,CMPK2,USF2,TMEM131,EHD1 |
| 2.012e-05 | -10.81 | GSE17721_POLYIC_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDM_UP | 190 | 38 | 17758 | 1761 |
LASP1,CHCHD7,ST14,S100A11,TSC22D3,DAP,PTTG1,MGST2,CCDC92,TAF1B,PTEN,SLC44A1,TMEM51,SORL1,BRI3,RFX5,PIK3CD,TMEM37,MX1,GCA,STAT4,SNTB2,CYS1,SAT1,SPTLC2,CASP4,STX3,ARF4,ATP13A2,BCAR3,NCOA3,C19orf66,NAT1,SPINT2,FAM110C,ZNF704,TRIOBP,TOB1 |
| 2.012e-05 | -10.81 | GSE17721_0.5H_VS_4H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDM_DN | 190 | 38 | 17758 | 1761 |
ARHGEF3,ENO2,CPEB4,IL15,TBC1D1,PPFIBP2,TAP1,IL18,MPP5,F11R,B4GALT4,REPS1,NRP2,RPS6KA2,XYLT2,LMO4,ECE1,CACNA1D,SGCB,ENPP4,GCA,BCL9,SYNE2,ASB13,FNDC3A,RNF19B,ALCAM,MAPKAPK2,ETS2,RBL1,C19orf66,NAT1,CSF1,ITGAV,PTGES,ABCA1,E2F8,RRAGD |
| 2.012e-05 | -10.81 | V$EGR2_01 | MSigDB lists | V$EGR2_01 | 190 | 38 | 17758 | 1761 |
CMAS,SCN5A,PCOLCE,MRC2,UBASH3B,THRA,DCAF7,TP53I11,VASH1,PDGFB,SPTB,HDAC9,WWP2,CDKN2C,TFAP4,RALGPS2,ITGB8,SH3BP1,WDR44,RRBP1,BCL6,SMYD5,ETV4,C9orf72,DVL2,MAP3K3,SIRT1,SUN2,ATL1,HMG20B,KIF1C,MAN2A2,ITPR1,KLF5,OSR1,ITPKA,NRGN,PTGES |
| 2.012e-05 | -10.81 | GSE3982_DC_VS_BCELL_UP | MSigDB lists | GSE3982_DC_VS_BCELL_UP | 190 | 38 | 17758 | 1761 |
LAMP1,SORT1,GALNT12,SDC4,MRAS,CENPN,PPP2R3A,ARHGEF10L,PDGFA,NOV,PAPSS1,MITF,DAPK1,ADCK2,TACSTD2,ACOX2,EGLN3,SPRY2,CTH,PDGFC,ALDH2,MPP1,ACO1,TNS1,STX3,RHEB,CD83,FUCA1,WIPI1,SETD3,P4HA2,FAM114A1,ARRB1,AURKA,FZD5,ARSB,SLC27A3,ACOT7 |
| 2.012e-05 | -10.81 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | 190 | 38 | 17758 | 1761 |
NFKBIE,PPP1R2,EPAS1,DCAF7,SDC4,TAP1,KIF23,NDUFA4,STIL,BMP2K,PSMD1,PTEN,AKR1B1,TRIM21,DIXDC1,OAS3,LMAN1,BTBD3,SCN3A,FAH,CKS2,CENPA,PLSCR1,SLC39A8,C3orf52,GGH,NUSAP1,PDK3,PCTP,STEAP1,SLCO4A1,MID1IP1,H1F0,TWSG1,RAB11FIP1,GLA,NCAPG2,SERPINB1 |
| 2.026e-05 | -10.81 | human chrXq23 | chromosome location | human chrXq23 | 29 | 10 | 26250 | 1887 |
DANT2,CAPN6,BHLHB9,ALG13,CUL4B,RGAG1,ZBTB33,CXorf56,NXT2,PLS3 |
| 2.028e-05 | -10.81 | KINASE_ACTIVITY | MSigDB lists | KINASE_ACTIVITY | 367 | 62 | 17758 | 1761 |
PINK1,CIT,RPS6KA1,GNE,DGKQ,ERBB2,TESK2,TGFBR1,TRIB2,DDR1,MERTK,NRP2,DAPK2,RPS6KA2,IGF1R,ARSG,PLK4,DLG1,SGK3,PIK3CA,NEK2,MAP3K9,SGK1,MAPK11,PIM1,ERBB3,PHKA2,PIKFYVE,DGKG,MAP3K3,PLK1,AKT1,RIPK2,TESK1,ACVR1C,PBK,MPP1,STRADB,EIF2AK1,PDK3,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,DGKE,CDK5R1,STK17A,MAPKAPK2,ACVRL1,STK38,PTK7,DCK,LIMK1,AXL,PRPS2,RYK,NR4A3,MAP3K5,ITPKA,HIPK3,MAPK12 |
| 2.044e-05 | -10.80 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 673 | 100 | 17775 | 1757 |
TRIP10,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,SP100,PIK3CA,PLK4,EPHB4,NEB,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,PRKAR2B,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,ABR,EPHA10,DUOX1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,BMP1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,DSE,MERTK,BMP2K,SNTA1,TMEM87B,ADRBK1,IGF1R,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,MYO5A,ABCC1,ADCK3,TESK1,ASPM,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,RANBP9,STK17A,MAPKAPK2,ACVRL1,FGFR2,PRCP,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK |
| 2.047e-05 | -10.80 | GCANCTGNY_V$MYOD_Q6 | MSigDB lists | GCANCTGNY_V$MYOD_Q6 | 863 | 123 | 17758 | 1761 |
CCNE2,EMX1,PPP4R4,REPS2,PPM1J,HEBP1,CAMKK1,DDIT4L,TSC22D3,HDAC11,ARFGEF1,MORC4,TDRKH,MORF4L2,CAMK1D,GRK6,PDGFB,SPTB,SLC9A7,SYTL2,CALM2,RNF220,STIM1,SH3BP1,RGS3,DACT1,CABP1,LMO4,SLC44A1,ENPP5,KCNS3,CDKN1B,DAB2IP,IQCD,NTN4,RASGEF1A,SULT2B1,MYT1,CLCN3,KCNIP3,SNTB2,TFAP2C,IGSF8,ATP1B1,DUSP4,PPP1R14C,ITPR3,SLC25A5,LHFPL2,RNF19B,COL12A1,ABR,PTPRJ,RBM47,KLF12,WIPI1,ZNF367,OVOL1,NRG1,EPB41L4A,NRGN,COBL,FBLIM1,FRMD4A,IGFBP6,CALM3,NDUFA4,RAB6A,PKN1,TNFRSF19,BEX2,PSIP1,PPP2R3A,HDAC9,TFAP4,FOXP2,IGF1R,GATA2,FLRT3,KIF13B,FUT8,SLC44A2,TSPAN13,ERBB3,NCAM1,CITED2,ZRANB1,TPCN1,DPYSL5,PVRL4,TGIF1,PLEKHA6,SLC37A1,LONRF3,TACC1,OXR1,CALM1,C1GALT1C1,PRICKLE1,TCF7,COL7A1,FOS,ARHGAP24,MMP15,PRKAG2,COQ10A,SMTNL2,ITGA7,PELI2,AMMECR1,SPINT2,NR4A3,AGBL5,RYK,GRIN2D,NR4A2,MAP3K5,DRP2,ZMIZ1,OSR1,SNPH,EGLN1,EHD1 |
| 2.115e-05 | -10.76 | leading edge membrane | cellular component | GO:0031256 | 135 | 30 | 17570 | 1756 |
DDX58,EPB41L5,SGCE,PACSIN2,RHOA,NF2,SYNE2,EPS8,GRIN1,SPATA13,GABRG2,EZR,CNTNAP2,NCKAP1,AIF1L,APC2,ANTXR1,EPS8L2,ARF4,RASGRP2,GABARAPL1,PTPRJ,ADORA1,NRG1,GPER1,PIEZO1,ITGAV,PACSIN1,SPRY2,ARHGEF4 |
| 2.120e-05 | -10.76 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11621 | 1226 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ENPP1,PLCG1,ATP7B,TRAF3IP1,FAM114A1,TMOD2,ITPKA,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,HPS3,NPHP3,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,TMEM173,ADAMTS16,DOCK9,PTTG1,GRK6,MGST2,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,ZNF365,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,DNAJB14,ZNF618,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,ISOC1,MAPK12,CTHRC1,ESRP1,HABP4,SDC4,CTSZ,PLPPR4,SLC25A43,FUT2,ITGB8,MGAT4A,FAM20B,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,THRB,CELSR2,STAU2,NFE2L1,CR2,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,KLF12,HOXA9,ARRDC1,KLF11,MYL12B,RRAGD,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,ADCK5,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,PRX,COL13A1,KBTBD2,PHLPP2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,EFNA5,IRF7,SYT13,ST3GAL1,ZMAT1,BIN1,CMAS,PINK1,CDH22,CPEB4,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,PARM1,VPS26A,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,HYLS1,MARCH2,METAP2,SPATA18,ACVR1C,KIF13A,LDB2,POR,PRIM1,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,TBC1D1,TNFRSF19,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,DAPK1,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,NPC2,ATP8B3,ANTXR1,NFIB,PLEKHH2,TJP3,FAAH,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,CCDC110,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,SULT2B1,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ITPR3,ASB13,ALCAM,ATP10D,AMZ2,DDOST,POPDC3,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,HLA-A,SLC25A36,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,ESPL1,MELK,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,RAB15,SIPA1L2,ARHGEF37,SIVA1,ANKFN1,TRPC1,MYRIP,BTBD3,CYP1B1,NLRP4,CENPA,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,COL16A1,AFAP1,CCNE2,LMO7,NCKAP5,LZTFL1,PDIA5,COL18A1,IL27RA,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,FANCE,ARHGAP35,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,MYCL,BMP7,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,PGM1,SYBU,TTC7A,LEPR,ARHGAP24,ENDOD1,SWAP70,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,ACACB,ADD1,IL15RA,MRPS15,AASS,MMADHC,CACNA2D2,DHX8,NRG2,IL18,SYTL4,CA8,BARD1,DAPK2,WEE1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,PIK3CD,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,E2F8,GAB1,FAM169A,ALDH6A1,NFKBIE,SLC36A4,MERTK,RAVER2,GNS,FAM189A1,NEK2,NCAM1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,ITPR1,AURKA,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,XDH,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,ENPP4,SSH3,FZD4,SYNE2,CDCA2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,GSTP1,ETS1,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,ANKS1B,ALG13,CALD1,PLEKHF1,ECI2,MAPK11,WWP1,NPTXR,CRTAP,AMOTL2,LCA5,FMN1,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,CYBRD1,DCBLD1,MYL9,UNKL,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,CNTRL,SHC3,MKRN3,ELF5,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,ZCCHC24,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,TESK1,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,EFR3A,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,MACC1,RUSC2,DAP,GNE,GABRG2,SELL,NKRF,SIRPA,PPP2R3A,SLC9A2,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,BCAR1,MAPK8IP1,PRDX4,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NMI,NETO2,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,CCNF,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,PLK2,GNPTAB,PTER,NKD1,DHTKD1,UNC5B,TANC2,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,B3GNT7,PMPCB,MMD,ZNF84,MFI2,TBC1D8B,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,ARMCX3,NLRX1,TRIP10,CAST,IQGAP1,RPS6KA1,BROX,RNF182,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,CDKN1B,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,CMTM7,PRDM11,NIN,EPHA10,JAK1,NRG1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SEPP1,SIX4,TMCC3,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,SPRY2,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,CCDC69,CSTF2,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CASP3,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,DENND2D,TMC1,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,ANKRD12,POF1B,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,RNF113A,GNAS,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,SLC25A24,FAM92A1,IL15,PSME2,TDRKH,LRRC45,SLC25A48,SETDB2,FRYL,RPN2,PDIA6,SCYL3,FRS3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,VSIG10,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,ASPM,DEPDC4,GCLC,MBNL3,LRRC66,OGDHL,KLHL2,HLA-B,C2orf70,PRCP,OTUB2,HOXB13,GEM,L1CAM |
| 2.161e-05 | -10.74 | adenyl nucleotide binding | molecular function | GO:0030554 | 1501 | 200 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ENPP1,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,BVES,DGKQ,ABCG2,KIF23,TEC,MERTK,BMP2K,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,AHCY,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,STK17A,DHX32,DGKH,MAPKAPK2,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,TMEM173,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,PDE4D,EPHB4,OAS3,ACSL4,SCYL3,SEPHS1,MYO5B,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,ATP10D,MAP3K6,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,TGFBR1,PKN1,DNAH3,KIF5B,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,UBE2J1,SGK3,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,MYO5A,ATP2B1,OPLAH,RAPGEF2,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,FGFR2,ACVRL1,ABCB1,RYK,LRRK1,CENPE,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 2.176e-05 | -10.74 | side of membrane | cellular component | GO:0098552 | 419 | 69 | 17570 | 1756 |
LAMP1,BCAM,SLC2A4,IQGAP1,CD274,CACNB4,SDC1,SPTB,TMC1,BCAP31,SCNN1A,CDH1,IL6ST,CABP1,DLG1,DAB2IP,ECE1,TIAM1,GM2A,CLCN3,EZR,CR2,CD40,ALCAM,TAPBP,JAK1,NRG1,EFNA5,TRAF5,ABCA1,SERPINE2,LGALS3,RASA2,HLA-F,ITGA6,HLA-E,SELL,TEC,PLPPR4,ANO1,HLA-A,ITGA3,PTEN,SNX18,CDK16,CD9,C10orf54,HLA-C,NCAM1,SYK,S100A6,YES1,GNA11,RASA1,FAS,CD83,GNAS,HLA-B,NUCB1,CTSV,ARRB1,CTSA,ITGAV,GEM,JAK3,L1CAM,ESYT2,CD33,ABCG1 |
| 2.195e-05 | -10.73 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 219 | 42 | 17758 | 1761 |
TRIM2,CPEB4,NUAK1,RASA2,SOX9,DNAJB11,MPP5,CAMK1D,HERC6,ZFYVE9,AKIRIN1,CTNNBIP1,ADD3,DPYSL2,RGS3,CABP1,VASN,MDFIC,TAGLN2,ACSL4,CITED2,SCN3A,MYO5A,MAP3K3,EPB41L5,AMOTL2,ZC3H11A,NFE2L1,YES1,FNDC3A,LHFPL2,DAG1,RASA1,ABR,FZD7,ARHGAP24,CACHD1,SLC4A4,KLF5,EIF4EBP2,SEMA3A,ABCA1 |
| 2.220e-05 | -10.72 | central nervous system development | biological process | GO:0007417 | 859 | 125 | 16441 | 1675 |
CASP3,EMX1,UGT8,GRHL2,NF2,HSPG2,AK7,THRA,CAST,HDAC11,EPHA4,TP53,ERBB2,NDRG2,DNER,STIL,PHLDA1,CALM2,TTC21B,CDKN2C,APLP2,CDH1,SHC3,DPYSL2,KIF14,LMO4,LHX6,ALDH1A3,SRR,DUSP10,DAB2IP,DIXDC1,NOTCH3,ZBTB18,BTBD3,SPEF2,MBP,TIMP2,CELSR2,FZD4,TFAP2C,KLK6,ARF4,ABR,ARHGAP35,NFIX,IRS2,MDK,ALDH5A1,PTPRJ,MAP2,AXL,NRG1,SERPINI1,NRGN,ANXA3,WASF3,SCN5A,CDH22,SERPINE2,HAPLN3,ADGRG1,SOX9,RAB23,PBX3,CALM3,CNTNAP2,NCKAP1,SEPP1,GSTP1,ETS1,HOXB2,HPCAL4,FZD6,MECOM,FOXP2,IGF1R,PTEN,GATA2,CST3,TFAP2A,BAX,PRKG1,CD9,WWP1,WNT3A,ALDH3A2,HES1,PDGFC,ARHGEF28,RHOA,TACC1,ASPM,RAPGEF2,CALM1,GRIN1,AK4,TCF7,SCRIB,BBS2,NFIB,CDK5R1,FAS,CDK5RAP1,PITX2,TIMP3,FAT4,FGFR2,TWSG1,PHLPP2,PLPP3,DBI,NR4A3,RYK,PCDH19,NR4A2,GDF11,WDR62,NDE1,DRP2,SOX8,ARSB,SHROOM2,SEMA3A,JARID2 |
| 2.221e-05 | -10.71 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | MSigDB lists | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | 36 | 13 | 17758 | 1761 |
PITX2,RPS6KA2,AKT1,PTEN,RPS6KA1,PLCG2,ITPR1,PIK3CA,NR4A3,ITPR2,ITPR3,SYK,GAB1 |
| 2.221e-05 | -10.71 | ST_ADRENERGIC | MSigDB lists | ST_ADRENERGIC | 36 | 13 | 17758 | 1761 |
PITX2,AKT1,ITPR1,PIK3R1,PIK3CA,ASAH1,PIK3CD,ITPR2,PHKA2,ITPKA,ITPR3,GNA11,DAG1 |
| 2.223e-05 | -10.71 | regulation of establishment of protein localization | biological process | GO:0070201 | 785 | 116 | 16441 | 1675 |
EXPH5,SORBS1,TXN,LGR4,THRA,IQGAP1,CACNA2D2,TP53,ERBB2,IL18,ITPR2,BCL2L1,SYTL4,CD274,HDAC6,PRKACA,BARD1,APC2,SLC8B1,ERP29,BCAP31,ARHGEF16,NOV,CDH1,SP100,DACT1,CABP1,KCNS3,DLG1,DAB2IP,TWIST1,MYRIP,F2R,MYT1,RASGRP1,CHP1,SIRT1,ERLEC1,AKT1,ACVR1C,PTGER4,NBPF3,EZR,PRKAR2B,PRKCQ,CD40,ITPR3,SLC25A5,SNX12,FZD7,IRS2,SLC25A4,PPP2R5A,DNM1L,RAB11FIP1,NOD2,EFNA5,NRG1,ARF6,F2RL1,DDX58,TCAF1,PINK1,BMF,NFKBIE,HLA-E,RAB23,PSMD10,TGFBR1,HMGN3,FBLN1,IL18R1,ANO1,WWP2,NEO1,KIF5B,CARD8,ITGA3,LLGL2,CDK16,BMP7,KCNN4,FAM20B,UBE2J1,TMBIM6,SORL1,MAPK11,MDFIC,CACNA1D,WNT3A,SYK,MDFI,EPB41L5,HES1,RHOA,PIK3R1,SYBU,LITAF,RGCC,CDK5R1,GPLD1,GNAS,NUCB1,BANK1,SYT7,TMEM30A,ITPR1,NFKBIA,ARRB1,YOD1,GPER1,SPCS3,FZD5,NDFIP1,TMEM173,PKIA |
| 2.224e-05 | -10.71 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1493 | 199 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ENPP1,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,BVES,DGKQ,ABCG2,KIF23,TEC,MERTK,BMP2K,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,STK17A,DHX32,DGKH,MAPKAPK2,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,TMEM173,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,PDE4D,EPHB4,OAS3,ACSL4,SCYL3,SEPHS1,MYO5B,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,ATP10D,MAP3K6,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,TGFBR1,PKN1,DNAH3,KIF5B,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,UBE2J1,SGK3,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,MYO5A,ATP2B1,OPLAH,RAPGEF2,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,FGFR2,ACVRL1,ABCB1,RYK,LRRK1,CENPE,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 2.245e-05 | -10.70 | SIGNAL_TRANSDUCTION | MSigDB lists | SIGNAL_TRANSDUCTION | 1606 | 208 | 17758 | 1761 |
CASP3,SIGIRR,BCAM,TXN,IL15RA,EPAS1,RET,EPHA4,NRG2,ITPR2,SLC20A1,CARD10,GRM5,HTR1D,ARHGEF10L,CALM2,DAPK2,RPS6KA2,SHC3,DPYSL2,RGS3,IL6ST,TSPAN6,IL31RA,DUSP10,TACSTD2,RASGRP1,KCNIP3,CASP9,ARHGDIB,PRKAR2B,ARFRP1,ROR1,STK17B,ADRBK2,RHEB,ABR,OPTN,EDNRA,DPYSL3,PGF,PLCH1,CARHSP1,DNM1L,LIMK1,PLK2,MADD,NOD2,ADIPOR1,ITPKA,ARF6,RAP1GAP,TRAF5,NRGN,F2RL1,GAB1,FGD1,PRKAA2,ARAP3,CDKN1C,CALM3,GPSM2,MERTK,IL18R1,IGF1R,RANBP1,DAPK1,OPN3,MAP3K9,PRKG1,CD70,MDFIC,OSTF1,PIKFYVE,PLCB2,NUP85,SOCS5,MDFI,DPYSL5,ELK3,RGMB,CORO2A,STAT4,CALM1,EPHA1,GNA11,CDK5R1,FAS,STK17A,BCAR3,MAPKAPK2,PTPRF,GNAS,GABRD,FGD6,LTBP2,PLD1,MAP3K5,IFI6,COL16A1,SPRED1,SORBS1,REPS2,NF2,IL15,S100A11,TRIP10,RALBP1,IQGAP1,RPS6KA1,INPP5D,RGS20,TP53,ERBB2,MRAS,IL27RA,IL13RA1,CD274,BCL2L1,MGST2,GRK6,APC2,TNFSF9,ZFYVE9,CDS1,PDGFA,ARTN,F2R,MED30,FRS3,MAP3K3,MX1,AKT1,RIPK2,PTPRU,PTGER4,RAD17,ERBB2IP,DUSP4,CD40,ITPR3,ALCAM,MAP3K6,SOCS3,IRS2,DUOX1,PTPRJ,PTK7,CORO1C,AXL,STK38,SECTM1,INPP4B,TLE1,RGS14,AIFM3,LIFR,NR3C2,ABCA1,MAPK12,ANXA3,PINK1,ARHGEF11,EPS8,GABRG2,PDIA3,TGFBR1,GDF15,CRABP2,PKN1,LGALS3BP,TOP2A,DIRAS3,CTNNBIP1,CARD8,ADORA1,ADRBK1,PTEN,BAX,SLC44A2,MAPK11,ERBB3,CITED2,S100A6,FARP2,RHOA,NR3C1,NR4A1,AMFR,MPP1,PIK3R1,LITAF,BCAR1,LEPR,MAPK8IP1,CD83,PRDX4,CNTNAP1,SCG2,ACVRL1,NMI,RYK,NR4A3,ARRB1,GEM,NDFIP1,ZBTB33,CD33 |
| 2.276e-05 | -10.69 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | 191 | 38 | 17758 | 1761 |
CASP3,LZTFL1,RUNX2,S100A11,PSME2,DAP,CYB561,NENF,CDKN2C,DAPK2,WEE1,METTL7A,SHC3,RRBP1,TRPC1,RAB20,CTTN,MINPP1,EGLN3,FAIM,F2R,GM2A,S100A6,METAP2,LAMP2,RASGRF1,PQLC3,LITAF,FURIN,HTATIP2,CASP4,FECH,ENPP1,UAP1,DBI,RYK,STK39,LRRK1 |
| 2.276e-05 | -10.69 | GSE7852_LN_VS_THYMUS_TCONV_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_UP | 191 | 38 | 17758 | 1761 |
NUDT6,AVPI1,TRIM2,PINK1,TTC39B,LGR4,HLA-E,DNAJB2,ITGA6,EFHD2,IL18R1,RAD23A,GNS,RCN1,APOBEC3B,SIPA1L2,CYP2S1,RUNDC3B,DAPK1,OSGIN1,S100A6,GCNT1,PLSCR1,RGMB,S100A4,SPNS3,CASP4,DGKE,SOCS3,HLA-B,ENPP1,BANK1,LRIG1,NR4A3,PNPLA6,STK39,CBX7,XDH |
| 2.276e-05 | -10.69 | GSE29618_MONOCYTE_VS_MDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_UP | 191 | 38 | 17758 | 1761 |
LAMP1,IL15,CD63,HLA-F,ASAH1,FAM198B,GRK6,ARHGEF40,IER3,ARHGEF10L,GNS,APLP2,FRY,DRAM1,SORL1,TIAM1,CKAP4,CYP1B1,CPD,S100A4,MPP1,CDA,NPC2,BLVRA,RNF19B,CRISPLD2,IRS2,HLA-B,HPSE,SERPINA1,SEMA4D,NFKBIA,CLMN,ZDHHC7,ADIPOR1,LTA4H,ABCA1,KLF7 |
| 2.276e-05 | -10.69 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | 191 | 38 | 17758 | 1761 |
FRMD6,DDIT4L,THRA,TSC22D3,ABCG2,IL27RA,HMGN3,SYTL4,M6PR,ZFYVE16,RCN1,RNF220,PTEN,SLC44A1,FXYD5,MDFIC,EPB41L4B,HLA-C,DGKG,TIPARP,SUN2,SHMT1,NR3C1,PTGER4,TNS1,ERBB2IP,ALCAM,STK17B,NFIX,HLA-B,TAPBP,NR1D2,PELI2,PRDM5,FAM117A,ISOC1,GAB1,FGD1 |
| 2.276e-05 | -10.69 | GSE13306_TREG_VS_TCONV_SPLEEN_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_UP | 191 | 38 | 17758 | 1761 |
PAPSS2,ZCCHC24,SDC4,BCL2L1,TP53I11,NUCB2,OAT,ADAMTSL4,ZNF385B,CYP26A1,KIF5B,SIPA1L2,IL6ST,ZDHHC23,SGK1,WWP1,ACOX2,PIM1,CNOT6L,MAST4,FAH,RIPK2,PTPN9,PCBP3,MPP1,DUSP4,PTGFRN,SESN1,TCEAL8,NFIX,ARHGAP35,DGKH,PTPRJ,SPINT2,PRDM5,PER3,SNX30,CD33 |
| 2.288e-05 | -10.69 | MODULE_137 | MSigDB lists | MODULE_137 | 526 | 82 | 17758 | 1761 |
TRIM2,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,APC2,PHLDA1,CABP1,LMO4,ALDH1A3,IFIT1,BTBD3,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,TLE1,SERPINI1,ITPKA,NRGN,BIN1,WASF3,COL9A3,CDH22,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,CALB2,SOX9,GABRG2,SLC1A3,CNTNAP2,SEPP1,TSPAN7,PARM1,ELF3,NEO1,DIRAS3,CA2,RIMS3,BDH1,IGFBP2,ALDH7A1,NCAM1,GAD1,RIMS2,FADS2,NR4A1,GRIN1,FOS,TIMP3,SERPINA1,SCG2,FGFR2,RND3,ITGA7,ITPR1,TCEAL4,CDK18,STK39,L1CAM,PKIA,SNPH,ARHGEF4 |
| 2.295e-05 | -10.68 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | 1705 | 219 | 17758 | 1761 |
CCNI,LTBP1,ACACB,TRIM2,IL15RA,VANGL1,SLC25A13,CUL4B,EPHA4,ARFGEF1,LACTB2,MORF4L2,FANCI,SH3KBP1,ARHGEF10L,CALM2,WEE1,SESN3,IL6ST,SLC44A1,PASK,PAPSS1,ELF5,KLF3,DLG1,RP2,CTTN,RCAN3,SMYD5,BTBD3,CYP1B1,SMARCA2,SH3BGRL,PBK,ITCH,CBX6,ROR1,GALNT7,ANLN,ZBTB7B,SESN1,COL12A1,HLF,MID1IP1,MAP2,DNM1L,KCNK1,LIMK1,PRKCDBP,AGFG2,MRPS28,EPB41L4A,WBSCR27,ARF6,F2RL1,E2F8,GAB1,NR2C2,RUNX2,ZNF395,CALM3,PSIP1,KIAA1161,RABGGTA,TFAP4,DAZAP1,IGF1R,SNX18,RANBP1,MDFIC,LIMCH1,CCDC88A,MCCC2,KDELR1,ABCC1,MDFI,FADS2,PMPCB,ELK3,ADCK3,CALM1,VWA1,ELK1,NUBP1,NFIB,FRMD4B,PTPRF,FECH,CACHD1,FAM64A,SLC4A4,PVRL2,TIMM8A,FAAH,H1F0,ITPR1,SLC4A3,RHOBTB2,PLD1,MAP3K5,PLIN3,PER3,SERPINB1,KLF7,DOCK9,EGLN1,SPRED1,SLC25A24,GRHL2,DLGAP5,NF2,FOXM1,THRA,ACTR8,CTDSPL,ERBB2,IL13RA1,NUF2,SLC7A2,EMP2,REPS1,IER3,RAD23A,EFR3A,FRYL,PLK4,BRI3,CDKN1B,GOT1,EPHB4,ACSL4,MINPP1,RAB27B,PHKA2,SULT2B1,CTDSP2,NAGA,FRS3,CAPN6,FIGNL1,PANK1,UTRN,SERTAD3,TMEM144,NUSAP1,ERBB2IP,DOCK5,NFIX,AMZ2,IDE,RBL1,NGFRAP1,ZNF704,EFNA5,LTA4H,ST3GAL1,ISOC1,TTC8,BIN1,GOLIM4,TSPAN15,ATP9A,DAP,RUSC2,FRMD6,ERI2,EFHD2,FBXO6,TRIB2,ETS1,LBR,HMGXB4,NRP2,TOP2A,C16orf74,KIF5B,RASSF8,CTNNBIP1,ADD3,CDK16,FJX1,FUT8,RRBP1,UBE2J1,SLC44A2,PLEKHF1,IGFBP2,IQGAP3,FAIM,CNOT6L,CLIP2,TLE6,GCNT1,MOSPD2,PLSCR1,NR3C1,BCL9,PIK3R1,YES1,GRTP1,BBS2,KIF11,CDK5RAP1,SWAP70,TIMP3,NR1D2,CDCA7L,RYK,CSTF2,PPP2R3C,SPCS3,ETAA1,CEP41,ICOSLG,OSR1,NCAPG2,UBE2C,NDFIP1,JARID2 |
| 2.312e-05 | -10.67 | POOLA_INVASIVE_BREAST_CANCER_DN | MSigDB lists | POOLA_INVASIVE_BREAST_CANCER_DN | 130 | 29 | 17758 | 1761 |
SSH3,KLK10,FRMD4A,CELSR2,NQO1,PEX6,PIK3R1,SDC4,FBXO2,COL4A5,TP53I11,KCTD2,LTBP3,IL17RB,PDGFA,CYP1A1,ITGA3,IGF1R,SLC27A6,ACADSB,ITGA7,XYLT2,ITPR1,MATN2,INPP4B,CLMN,IGFBP2,CACNA1D,ECE1 |
| 2.319e-05 | -10.67 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 393 | 65 | 17775 | 1757 |
RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,WEE1,RPS6KA2,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,LIFR,HOXC13,MAPK12,CDK17,MRC2,PINK1,GNE,NEO1,IGF1R,CDK16,MAP3K9,DAPK1,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,ADCK3,PIK3R1,PIP4K2C,AK4,EIF2AK1,MAML2,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,JAK3 |
| 2.319e-05 | -10.67 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 393 | 65 | 17775 | 1757 |
RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,WEE1,RPS6KA2,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,LIFR,HOXC13,MAPK12,CDK17,MRC2,PINK1,GNE,NEO1,IGF1R,CDK16,MAP3K9,DAPK1,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,ADCK3,PIK3R1,PIP4K2C,AK4,EIF2AK1,MAML2,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,JAK3 |
| 2.319e-05 | -10.67 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 393 | 65 | 17775 | 1757 |
RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,WEE1,RPS6KA2,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,LIFR,HOXC13,MAPK12,CDK17,MRC2,PINK1,GNE,NEO1,IGF1R,CDK16,MAP3K9,DAPK1,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,ADCK3,PIK3R1,PIP4K2C,AK4,EIF2AK1,MAML2,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,JAK3 |
| 2.319e-05 | -10.67 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 393 | 65 | 17775 | 1757 |
RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,WEE1,RPS6KA2,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,LIFR,HOXC13,MAPK12,CDK17,MRC2,PINK1,GNE,NEO1,IGF1R,CDK16,MAP3K9,DAPK1,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,ADCK3,PIK3R1,PIP4K2C,AK4,EIF2AK1,MAML2,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,JAK3 |
| 2.319e-05 | -10.67 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 393 | 65 | 17775 | 1757 |
RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,WEE1,RPS6KA2,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,LIFR,HOXC13,MAPK12,CDK17,MRC2,PINK1,GNE,NEO1,IGF1R,CDK16,MAP3K9,DAPK1,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,ADCK3,PIK3R1,PIP4K2C,AK4,EIF2AK1,MAML2,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,JAK3 |
| 2.324e-05 | -10.67 | negative regulation of kinase activity | biological process | GO:0033673 | 221 | 43 | 16441 | 1675 |
CASP3,SPRED1,NF2,CDKN1C,UBASH3B,DNAJC3,PKN1,TRIB2,GSTP1,TFAP4,CDKN2C,IGF1R,PTEN,BMP7,RGS3,DUSP10,CDKN1B,SORL1,DAB2IP,CDKN2D,SPRY2,SOCS5,CHP1,PLK1,SIRT1,AKT1,PRKAR2B,EPHA1,DUSP4,MAPK8IP1,SOCS3,CDK5RAP1,IRS2,PRKAG2,PTPRJ,PPP2R5A,STK38,CORO1C,RGS14,UBE2C,HSPB1,HIPK3,PKIA |
| 2.329e-05 | -10.67 | Immune System | REACTOME pathways | R-HSA-168256 | 1371 | 189 | 8202 | 867 |
SIGIRR,TRIM2,TXN,TAP1,FBXO2,NRG2,IL18,PSME1,ITPR2,PJA2,PDGFB,TRIM68,SPTB,SH3KBP1,CALM2,AP1M2,PSMD1,RPS6KA2,ELMO2,SHC3,STIM1,IL6ST,PIK3CA,DUSP10,TRPC1,IRF2,PIK3CD,RASGRP1,ERAP2,NLRP4,TRIM8,CD55,USP18,ITCH,CASP9,AGO4,PRKAR2B,RNF19B,TRIM9,PLCG1,LIMK1,NOD2,RAP1GAP,GAB1,DDX58,MRC2,NFKBIE,LGALS3,HLA-E,HLA-F,RASA2,ASB9,KIF23,CALM3,TEC,NCKAP1,PHLPP1,UBE2Q2,PIK3AP1,PRKG1,CD70,TNFRSF12A,HLA-C,NCAM1,NUP85,KIF20A,MICB,CALM1,IFIT3,ELK1,PSMA4,RASA1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,PELI2,NFKBIA,ITPR1,NLRC5,CTSA,PLD1,ARPC2,FBXO27,JAK3,IFIH1,IFI6,NUP58,TMEM173,SPRED1,NLRX1,PSME2,IQGAP1,RPS6KA1,INPP5D,ERBB2,RNF182,CD274,BCL2L1,PRKACA,PDGFA,ATP6V0B,RNF220,CDH1,SP100,PLCG2,CDKN1B,DAB2IP,IFIT1,OAS3,LGMN,RASGEF1A,FRS3,MAP3K3,MX1,SEC23A,SEC61B,RIPK2,AKT1,CDC20,PRKCQ,DUSP4,ASB13,ITPR3,CD40,CASP4,SOCS3,IRS2,TAPBP,PTPRJ,PPP2R5A,JAK1,DDOST,NRG1,IRF7,SPTBN5,MAPK12,WASF3,TNRC6C,KLHL13,SELL,PSMD10,HERC5,PDIA3,FBXO6,FGF19,HLA-A,KIF5B,DTX3L,ADRBK1,PTEN,CTSC,UBE2J1,KLC3,TRIM21,MAPK11,WWP1,ERBB3,CNPY3,TRIM62,SYK,MYO5A,RASGRF1,PSMB4,IFITM3,NR4A1,RAPGEF2,PIK3R1,UBE2A,GRIN1,PELI3,YES1,KIF11,FOS,DCTN6,CTSL,HLA-B,FGFR2,TRIM69,CTSV,DTX4,ERAP1,ARRB1,GRIN2D,ITGAV,CENPE,ICOSLG,UBE2C,CD33 |
| 2.329e-05 | -10.67 | establishment of localization | biological process | GO:0051234 | 3816 | 457 | 16441 | 1675 |
LAMP1,SLC35D2,ACACB,ADD1,TSC22D3,SLC25A13,ATP8A1,CACNA2D2,TAP1,TGOLN2,SYTL4,CCNB1,SLC20A1,SLC9A7,NCS1,CALM2,PQLC2,AP1M2,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,TINAGL1,PIK3CD,TMEM37,MARCH2,PACSIN1,XKR8,LAMP2,ORAI2,SLC35C1,PRKAR2B,KIF13A,LOXL2,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,ARF4,ENPP1,PLCG1,SLC25A4,DNM1L,LIMK1,GNPTAB,ATP7B,TRAF3IP1,NOD2,SARAF,ARF6,F2RL1,NXT2,SCN5A,MRC2,NFKBIE,GGA1,RAB23,SLC25A27,NDUFA4,SLC36A4,GPSM2,SLC1A3,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,DOPEY2,SNX18,ATP5H,RIMS3,RPL39,SLC16A6,RANBP1,PCYOX1,SORL1,CADPS2,PANX2,CACNA1D,PIKFYVE,SYTL3,NUP85,C9orf72,PPP6R1,RIMS2,TRAK2,PMPCB,KCNJ12,SLC37A1,KIF20A,MFI2,CALM1,ANO6,ERO1A,NPC2,ATP8B3,PCTP,SFXN5,STX3,CYB5A,SLCO4A1,CACHD1,AP1AR,GABRD,SCARB2,PRKAG2,SLC4A4,TIMM8A,CSNK1G1,ITPR1,SLC4A3,FAM83D,NDE1,ARPC2,PLIN3,HOOK1,NRBP1,NUP58,XDH,EHD1,PLA2G4A,MFSD3,MTM1,CCDC109B,SLC2A4,DLGAP5,TRIP10,RALBP1,ATP2C2,C5orf30,PKP2,FTH1,BCL2L1,CD274,MVB12B,PRKACA,DDR1,TMPRSS4,ZFYVE9,APPBP2,CCND1,SCNN1A,CDH1,CDKN1B,CNNM4,IFIT1,ACSL4,ARL4D,RAB27B,SNX10,TMEM9,SCN3A,ATG4D,MYO5B,SEC23A,SEC61B,COG2,FZD4,SYNE2,KIF1C,HTATIP2,NUSAP1,SLC11A2,ATP1B1,RAB38,ITPR3,SNX12,ATP10D,DDOST,CORO1C,SLC9A6,AXL,SLC27A1,PRIMA1,RGS14,SLC25A30,DENND5B,TTC8,TCAF1,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,CYB561,ANO9,SLC25A43,LGALS3BP,PDIA4,SLC25A36,CXCL16,ADD3,SLC27A6,CTSC,SGK3,CD9,BAX,KLC3,ATP8B1,SLC44A2,WWP1,SLC16A5,SPRY2,TPCN1,S100A6,NCOA2,ACBD5,ZWINT,LCA5,ZC3H11A,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,FURIN,PARP4,YES1,NEURL1B,CPTP,GPLD1,MAMDC4,RPL12,FGFR2,RAB11FIP2,SYT7,DBI,ABCB1,NR4A3,GRIN2D,ITGAV,CENPE,ARSB,USF2,SLC25A38,ESPL1,CYBRD1,ESYT2,EXPH5,ILDR1,CRYM,CPT2,ARFGEF1,NDC80,F11R,MPP5,ITPR2,HDAC6,CACNB4,PDGFB,NUP62CL,ERP29,SLC8B1,DNER,TMC1,SH3KBP1,ABCD4,SUSD2,ZFYVE16,RAB15,NPNT,DPYSL2,SLC44A1,ABCA2,DLG1,TRPC1,RAB20,RP2,CTTN,ANO4,SLC39A10,SCARA3,TRAM1,MYRIP,S100A13,RASGRP1,PLK1,KCNIP3,CENPA,CELSR2,STAU2,EZR,ARFRP1,ADRBK2,OPTN,EDNRA,TRIM9,KCNMB4,KCNK1,UEVLD,WIPI1,RAB11FIP1,PIEZO1,PCSK5,PRKAA2,GRN,LASP1,ARAP3,PEX6,BVES,FXYD3,SLC22A31,ABCG2,CALM3,RAB6A,NCKAP1,ANO1,CA2,RINL,GATA2,FRAS1,KIF13B,KCNN4,EXOC8,FXYD5,SELK,GAD1,SLC12A2,SNX7,ABCC1,KDELR1,BTN3A2,STRADB,SCRIB,EIF2AK1,MFSD7,STEAP1,GNAS,MAPKAPK2,SLC6A6,PVRL2,TMEM30A,MFSD2A,CDCA5,NFKBIA,SLC2A6,SH3BP4,ZDHHC7,CTSA,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,JAK3,TOB1,APOL2,NIPA1,SNX30,DYNLRB1,SLC25A24,SORBS1,UPF3B,TP53,SLC7A2,EMP2,BCAP31,SYTL2,TTC21B,PDGFA,SLC25A48,ATP6V0B,SVBP,ZDHHC12,KIF14,PLCG2,REEP1,FABP6,BCL6,ZDHHC23,RPN2,SCN2A,LMAN1,F2R,GM2A,CHP1,PPIF,CLCN3,AKT1,SLC39A8,OSTM1,ACO1,DAG1,ATP13A2,TAPBP,ALDH5A1,ATP1A1,PEX2,SPTBN5,SYT13,ABCA1,ARFGEF3,BIN1,ANXA3,PINK1,MFSD14B,SORT1,PACSIN2,GOLIM4,CD63,TSPAN15,LRP4,CDCA8,GABRG2,CRABP2,AIP,VPS26A,HMGXB4,SLC9A2,ZDHHC21,M6PR,TMEM63A,KIF5B,ADORA1,ADRBK1,MLPH,LLGL2,CDK16,RRBP1,SGK1,ABCD1,SYK,ATP2B1,MYO5A,SUN2,HES1,SYPL1,RAB3B,FBLN5,PPARA,PRICKLE1,COL7A1,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,ARRB1,SPCS3,MCUR1,GEM,CEP41,NDFIP1,TBC1D4,ARHGEF9,RAB3IL1,ABCG1,SNPH |
| 2.349e-05 | -10.66 | CORDENONSI_YAP_CONSERVED_SIGNATURE | MSigDB lists | CORDENONSI_YAP_CONSERVED_SIGNATURE | 57 | 17 | 17758 | 1761 |
HMMR,AMOTL2,CDC20,ETV5,HEXB,TNS1,GGH,EMP2,SH2D4A,CDKN2C,TOP2A,CTGF,CYR61,AXL,AGFG2,SGK1,MDFIC |
| 2.392e-05 | -10.64 | centrosome localization | biological process | GO:0051642 | 18 | 9 | 16441 | 1675 |
SUN2,ASPM,SYNE2,DLG1,EZR,AURKA,NDE1,NUBP1,NIN |
| 2.404e-05 | -10.64 | vacuolar part | cellular component | GO:0044437 | 397 | 66 | 17570 | 1756 |
LAMP1,GAA,HSPG2,HEXB,SDC1,ABCD4,DAPK2,ATP6V0B,PQLC2,AP1M2,ABCA2,RPN2,ECE1,MARCH2,TSPAN1,LGMN,TMEM9,GM2A,LAMP3,LAMP2,EVA1A,OSTM1,SLC11A2,RHEB,GABARAPL1,ATP13A2,ENPP1,HPSE,WIPI1,GLA,STARD3NL,RRAGD,MAN2B2,SORT1,CD63,TMEM55B,SDC4,ASAH1,SLC36A4,M6PR,TMEM63A,GNS,MARCH8,ZNRF2,VASN,COL6A1,GALNS,PCYOX1,DRAM1,SLC44A2,PLEKHF1,TPCN1,MMD,GUSB,IFITM3,LITAF,GNA11,GPLD1,CTSL,FUCA1,SCARB2,CTSV,ARRB1,CTSA,PLD1,ARSB |
| 2.448e-05 | -10.62 | cellular process | biological process | GO:0009987 | 14182 | 1498 | 16441 | 1675 |
AK7,SLC25A13,HEXB,RET,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,HPCAL4,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,MYDGF,PANX2,DGKG,ULBP2,MYLIP,NUP85,PPP6R1,MCCC2,PAQR7,REC8,HPS3,PQLC3,PYM1,ERO1A,ELK1,NPHP3,PSMA4,GNA11,SFXN5,PLIN5,SLC4A4,ETS2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,DOCK9,NQO1,INPP5D,CD82,PTTG1,C5orf30,GRK6,MGST2,MVB12B,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,DLG3,RASGEF1A,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,SEPT6,PTPN9,SAT1,HTATIP2,XRCC6BP1,GTF2A2,SNX12,ZNF618,COX20,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,MAPK12,CTHRC1,CKAP2,DCAF7,ESRP1,SDC4,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,CST3,BAX,KLC3,IGFBP2,MED22,PARP9,ACBD5,PVRL4,OPLAH,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,NR4A3,OSER1,ITGAV,CMPK2,OSR1,WDR45B,ACOT7,TLL2,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,ITPR2,MGAT5B,SPTB,FANCI,PLS3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,PAPL,SLC44A1,MITF,PASK,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,HS6ST1,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,MYL12B,RRAGD,RUNX2,LMTK3,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,TBCD,SELK,AHCY,PIM1,FAR2,WNT3A,CKAP4,DPYSL5,PCDH1,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,PRX,CDK5R1,FOXD2,RASGRP2,COL13A1,PHLPP2,KBTBD2,P4HA3,SLC2A6,ZDHHC7,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,ZDHHC23,CDH3,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,PTPRJ,IDE,ABHD12,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,H1FX,DNAJB9,FZD6,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,TSPAN13,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,PLAUR,STMN3,MAML2,GGH,COL7A1,BBS2,RNPEP,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,SSH1,LGR4,HSPG2,TSC22D3,PSME1,NANS,CAMK1D,VASH1,PJA2,OAT,SLC9A7,TYMP,CYP1A1,ZNF823,PALD1,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,TACSTD2,MARCH2,ZBTB18,METAP2,SPATA18,ACVR1C,SLC35C1,KIF13A,POR,PRIM1,PRDM5,BMP1,NFKBIZ,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,THEMIS2,TMEM55B,HERC6,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,VASN,PPP4R1,DAPK1,TPST1,ADCK2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,ADCK3,LPGAT1,CALM1,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,MMP15,SLCO4A1,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,MATN2,AGBL5,FAM83D,SFMBT1,CABIN1,CDK18,KLK7,PER3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,ST14,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,COG2,FOXJ2,DRAP1,PANK1,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,IGFBP6,CENPI,EPS8,PBX3,HERC5,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,ADGRB2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,GNB5,RNF128,FJX1,FUT8,DRAM1,CD9,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,ZKSCAN2,FBXO9,DIAPH2,YES1,FOS,ARSK,KIF11,CPTP,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,WDR62,FZD5,ESPL1,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,HSF2,SIVA1,CEP78,TRPC1,CTTN,BTBD3,SP5,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,PDE5A,VWA1,NUBP1,PDIK1L,RANBP9,MFSD7,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,LMO7,CCNE2,LZTFL1,DYNLRB1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CHP1,CKS2,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,ALDH5A1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,RBMS2,MYO5A,B3GALT6,PGM1,CFAP46,RC3H2,RGCC,NADK2,TTC7A,RUNX3,TCEAL8,FOXL1,LEPR,ENDOD1,CTSL,ARHGAP24,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,ACACB,KLK10,IL15RA,ADD1,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,NRG2,DHX8,IL18,MORF4L2,SYTL4,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,PSMD1,PQLC2,CYP2S1,ALDH1A3,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,ICMT,CYP4F3,COL12A1,PGF,DNM1L,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,GAB1,HOXC13,ALDH6A1,NFKBIE,NUAK1,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,NDE1,ARPC2,ZNF502,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,GRHL2,TMSB15A,GALNT12,ACTR8,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,CYS1,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,TRABD2A,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,ETS1,GSTP1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,CTSC,ARSG,ALG13,CALD1,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,NEURL1B,CRISPLD2,GALNT3,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,PPM1J,CUL4B,EPHA4,NDC80,HDAC6,PDGFB,SDC1,SHC3,CNTRL,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,DDX59,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,H1F0,PVRL2,ITGA7,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,IFI6,NIPA1,RNF146,AVPI1,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,LHX6,PLCG2,SRR,SCN2A,MINPP1,EGLN3,GM2A,DVL2,CTH,CPD,SIRT1,TIMP2,MBP,EVA1A,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,MFSD14B,PACSIN2,MACC1,CD63,ADGRG1,DAP,BLVRB,GNE,SWI5,GABRG2,PSMD10,SELL,NKRF,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,ABCD1,KLF9,FAIM,TLE6,FAH,DLGAP1,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,PELI3,FNDC3A,BORA,BCAR1,MAPK8IP1,SCRN2,PRDX4,CD83,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,CDCA7L,NMI,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,CTGF,ELMO2,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,PACSIN1,RCAN3,XKR8,LAMP2,ORAI2,LOC81691,KIFC2,PBK,CASP9,AGO4,TNS1,PIF1,GALNT7,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,GNPTAB,PTER,NKD1,DHTKD1,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,KIAA1161,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,BDH1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,MMD,MICB,AMER1,ANO6,PIP4K2C,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,DCK,CSNK1G1,SLC4A3,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,CAST,KCTD12,RNF182,CD274,AIFM2,MNS1,APLP2,ZNF75D,DOK4,CNNM4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,CMTM7,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,LGALS3BP,TEAD3,SIX4,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,CSTF2,PGM2L1,GRIN2D,GPER1,ARSB,NCAPG2,SLC25A38,CPEB2,OCLN,JARID2,EXPH5,EMX1,LTBP1,CASP3,NMRK1,CPT2,CAMKK1,CACNB4,DNER,KREMEN1,TMC1,TSEN34,PTCHD4,SH3KBP1,ABCD4,CHPF,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,STRIP2,ROR1,MRPS36,PTGFRN,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ZNF114,UEVLD,ADIPOR1,RAP1GAP,CPPED1,GRN,FAM213B,PIFO,LRRFIP2,PEX6,PHLPP1,ZNF432,OTUD1,CA2,KCNN4,DIAPH2-AS1,FXYD5,RFX5,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,AMDHD1,GLCE,GNAS,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,PLPP3,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,SLC25A48,SS18,SVBP,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,GOT1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CYP2U1,REEP4,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,POC1B,LRP4,MIER3,AES,NOTUM,TRMT2B,POMGNT1,SAC3D1,IL17RB,ADORA1,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,OGDHL,KLHL2,HLA-B,DHRS2,HNRNPH2,OTUB2,HOXB13,GEM,SOX8,L1CAM,SNPH |
| 2.452e-05 | -10.62 | Pkinase | pfam domains | PF00069 | 352 | 61 | 16629 | 1696 |
PRKAA2,CDK17,PINK1,NUAK1,CIT,CAMKK1,RPS6KA1,TGFBR1,CAMK1D,GRK6,TRIB2,PKN1,PRKACA,BMP2K,DAPK2,WEE1,RPS6KA2,ADRBK1,CDK16,PASK,SGK3,DAPK1,PRKG1,PLK4,MAP3K9,NEK2,SGK1,BUB1,MAPK11,PIM1,MAST4,SCYL3,MAP3K3,PLK1,AKT1,PBK,STRADB,PRKCQ,EIF2AK1,PKMYT1,PDIK1L,MAP3K6,STK17B,ADRBK2,CDK1,STK17A,MAPKAPK2,STK26,CDK19,CSNK1G1,PLK2,STK38,AURKA,CDK18,STK39,LRRK1,MAP3K5,NRBP1,HIPK3,MELK,MAPK12 |
| 2.458e-05 | -10.61 | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 220 | 42 | 17758 | 1761 |
SERPINE2,ZCCHC24,CD82,ETV5,CTDSPL,RET,ARL4C,EMP2,MNS1,MECOM,NEO1,HDAC9,SS18,CYR61,METTL7A,ZFP36,UBE2J1,TMEM51,LIMCH1,HLA-C,FAIM,ALDH3A2,NCOA2,ATP2B1,GFPT1,TGIF1,ING1,MBP,NR3C1,S100A4,HTATIP2,FOS,IDH1,GABARAPL1,STK17A,ETS2,KCNK1,HOXA9,SLC9A6,RAP2C,ERAP1,PITPNA |
| 2.504e-05 | -10.60 | positive regulation of protein catabolic process | biological process | GO:0045732 | 250 | 47 | 16441 | 1675 |
DLGAP5,GGA1,DNAJB2,PSME2,CUL4B,SOX9,ASB9,PSMD10,PSME1,TRIB2,CCNB1,BARD1,APC2,BCAP31,PPP2R3A,IER3,PSMD1,RNF128,CTSC,PTEN,DACT1,CDKN1B,SORL1,DAB2IP,MYLIP,TIPARP,SOCS5,PLK1,AKT1,PSMB4,ITCH,GCLC,NUB1,CDC20,FURIN,PRICKLE1,EZR,RNF19B,PSMA4,CDK1,GPLD1,PLK2,NKD1,AURKA,NDFIP1,UBE2C,ESPL1 |
| 2.513e-05 | -10.59 | KUMAR_TARGETS_OF_MLL_AF9_FUSION | MSigDB lists | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 385 | 64 | 17758 | 1761 |
PLA2G4A,TXN,TTC39B,DNAJC3,DDR1,PLS3,RNF220,IMPAD1,CYP2S1,DAB2IP,IFIT1,F2R,SMAGP,LOC81691,CLCN3,CD55,AKT1,USP18,CBX6,PTGER4,PRKCQ,ATP1B1,C15orf39,IDH1,NFIX,ANKRD10,MID1IP1,HOXA9,PRDM5,IRF7,SEMA6B,GOLIM4,TM2D2,SDC4,CYB561,TNFRSF19,PSIP1,LGALS3BP,B4GALNT1,M6PR,RALGPS2,TAF1B,CTSC,CD9,ALDH7A1,TSPAN13,CITED2,SLC12A2,PGM1,GUSB,SPATA13,TCF7,IFIT3,SPTLC2,TP53INP2,CD83,GALNT3,H1F0,TMEM30A,DCK,STK39,ATP1B3,CMPK2,RUSC1 |
| 2.520e-05 | -10.59 | carbohydrate derivative binding | molecular function | GO:0097367 | 2195 | 278 | 16491 | 1673 |
ACACB,AK7,ATP8A1,RET,TAP1,FBXO2,DHX8,CAMK1D,DAPK2,WEE1,CTGF,UBE2T,PIK3CA,TUBG1,PIK3CD,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,CDA,PRKAR2B,KIF13A,PIF1,POR,ARF4,PGF,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,ITPKA,ARF6,DDX58,CDK17,NUAK1,DGKQ,RAB23,KIF23,MERTK,BMP2K,C9orf69,ITGA3,CYR61,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAST4,DGKG,MCCC2,KIF20A,ADCK3,PIP4K2C,EPHA1,ATP8B3,GNA11,RASA1,STK17A,DHX32,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,FBXO27,MAP3K5,IFIH1,NRBP1,TMEM173,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TESK2,GRK6,PRKACA,DDR1,NOV,APLP2,CDH1,TRANK1,PDE4D,EPHB4,ACSL4,RAB27B,ARL4D,MYO5B,MX1,RIPK2,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,JAK1,CDK19,STK26,AXL,MLKL,MAPK12,PCOLCE,HAPLN3,ATP9A,ARL4C,FBXO6,PKN1,DNAH3,DIRAS3,FAM20B,SGK3,ATP8B1,MAPK11,ERBB3,OPLAH,RAPGEF2,UBE2A,AK4,YES1,KIF11,CPTP,CRISPLD2,FGFR2,ACVRL1,ABCB1,RYK,LRRK1,CENPE,CMPK2,MELK,RGMA,NMRK1,CAMKK1,EPHA4,VARS2,SDC1,ABCD4,RAB15,RPS6KA2,PASK,PAPSS1,ABCA2,RAB20,RP2,MYH14,DDX59,RASGRP1,NLRP4,PLK1,ATL1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,RHEB,DPYSL3,MDK,MAP2,PIK3C2B,GLA,RRAGD,PRKAA2,LMTK3,RUNX2,SERPINE2,BVES,PEX6,ABCG2,TEC,RAB6A,UBE2Q2,IGF1R,KIF13B,PIM1,ABCC1,PODXL2,TESK1,GYLTL1B,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,MAPKAPK2,GNAS,NUDT16,COL13A1,PRPS2,NLRC5,ALPK3,RHOBTB2,LTBP2,JAK3,RNF146,UGP2,TP53,ERBB2,MRAS,SYTL2,KIF14,SRR,PLK4,OAS3,SCYL3,SEPHS1,MAP3K3,CLCN3,ERLEC1,AKT1,FIGNL1,MAP3K6,DAG1,ATP13A2,ARHGAP35,ATP1A1,IDE,PTK7,STK38,ANXA9,ABCA1,PINK1,TOR4A,CIT,GNE,SELL,TGFBR1,NRP2,TOP2A,KIF5B,ADRBK1,ADORA1,CDK16,BMP7,UBE2J1,GTF2F2,SGK1,ABCD1,BUB1,SYK,MYO5A,ATP2B1,HMMR,RHOA,RAB3B,PSMB4,GCLC,NADK2,RUNX3,DGKE,CTSL,SWAP70,SERPINA1,RND3,RAP2C,GEM,UBE2C,L1CAM,HIPK3,ABCG1 |
| 2.529e-05 | -10.59 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | 171 | 35 | 17758 | 1761 |
ARHGEF11,UBASH3B,TSC22D3,EPHA4,HABP4,NDC80,SNN,SYTL2,H1FX,MARCH8,C16orf74,LLGL2,TAGLN2,MARCH2,PDE4D,SLC16A5,SUSD3,REC8,ITCH,DIAPH2,LDB2,FOS,TP53INP2,RASGRP2,SOCS3,IRS2,PELI2,CCDC69,ARRB1,FAM117A,FHL1,PIEZO1,TOB1,MAFF,PCSK5 |
| 2.558e-05 | -10.57 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | 178 | 36 | 17758 | 1761 |
DDX58,SEMA6B,CCDC109B,IL15,TAP1,HERC5,SAMD9,CD274,OSR2,HERC6,PRRG4,TMCC3,DTX3L,OTUD1,ZNF687,FAM46A,ZNRF2,OAS3,ETV7,APOBEC3G,LAMP3,AMOTL2,PCGF5,ARAP2,PLSCR1,IFIT3,PRX,FAS,GALNT3,C19orf66,SECTM1,NLRC5,IRF7,CMPK2,IFIH1,RARG |
| 2.558e-05 | -10.57 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 178 | 36 | 17758 | 1761 |
DDX58,SERPINE2,CDKN1C,IL15,MACC1,GALNT12,HERC5,SAMD9,DHRS3,LGALS3BP,EPCAM,SLC27A6,CDH1,IL31RA,IFIT1,OAS3,SCN2A,RAB27B,EGLN3,MX1,USP18,PRKAR2B,DUSP4,IFIT3,TRIM9,MFAP3L,TIMP3,HOXA9,INPP4B,IRF7,NR4A2,HS3ST3B1,GEM,CMPK2,IFIH1,IFI6 |
| 2.560e-05 | -10.57 | XU_AKT1_TARGETS_6HR | MSigDB lists | XU_AKT1_TARGETS_6HR | 27 | 11 | 17758 | 1761 |
MX1,TCTN2,PLSCR1,HERC5,IRF7,ERBB2IP,IFIT1,OAS3,IFIT3,IFIH1,IFI6 |
| 2.560e-05 | -10.57 | PETROVA_PROX1_TARGETS_UP | MSigDB lists | PETROVA_PROX1_TARGETS_UP | 27 | 11 | 17758 | 1761 |
TOP2A,CCNE2,GPRC5B,CDKN1C,PDLIM3,NDC80,MYBL2,BTBD3,UBE2C,CDK1,SMAGP |
| 2.571e-05 | -10.57 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | 192 | 38 | 17758 | 1761 |
SLC35D2,LGALS3,ASAH1,EFHD2,NDRG2,KCTD12,IL18,DHRS3,SIRPA,LMNA,APLP2,CST3,AIM1,BCL6,AKR1B1,SGK1,CDKN1B,MTMR11,OAS3,ALDH3A2,ATP2B1,PPIF,IFITM3,S100A4,SAT1,PTGER4,ATP1B1,DOCK5,SERPINA1,PRCP,LIMK1,TCEAL4,ARRB1,KLF11,EIF4EBP2,SERPINB6,AHR,CD33 |
| 2.571e-05 | -10.57 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | 192 | 38 | 17758 | 1761 |
GCLM,DLGAP5,HJURP,IL13RA1,CCNB1,PHLDA1,FANCI,IER3,TOP2A,TNS3,TYMP,BDH1,RANBP1,DAPK1,TUBG1,FAH,CKS2,LAMP3,HMMR,SHMT1,ALDH2,ZWINT,CENPA,KIF20A,ASPM,UBE2A,KIF11,IDH1,PRIM1,LRRC42,SLCO4A1,CSTF2,AURKA,NCAPG2,CCNB2,ESPL1,ACOT7,MELK |
| 2.571e-05 | -10.57 | GSE15767_MED_VS_SCS_MAC_LN_UP | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_UP | 192 | 38 | 17758 | 1761 |
MAN2B2,REPS2,PYROXD2,LRP4,EPHA4,KIF23,SELL,ASAH1,F11R,DSE,NUCB2,TMPRSS4,NRP2,TMCC3,CDS1,ATP6V0B,B3GALNT1,FAM46A,TSPAN6,SUSD3,PVRL4,DOCK4,PDGFC,ALDH2,IFITM3,HSPA12A,NPC2,RAB38,FOS,ATP13A2,BFSP1,SMTNL2,RBM47,ACVRL1,DBI,NCAPG2,GAB1,ABCA1 |
| 2.571e-05 | -10.57 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | 185 | 37 | 17758 | 1761 |
PRKAA2,SERPINE2,EPAS1,ST14,UBASH3B,ARMC7,ASAH1,KCTD12,ADAMTSL4,EPDR1,TMEM63A,RCN1,CD109,ATP6V0B,RNF128,RGS3,MGAT4A,ADAM15,RASGRP1,SMARCA2,LOC81691,CITED4,TESK1,LPGAT1,PLEKHO1,PTGER4,GGH,YES1,TP53INP2,STK17B,PLCG1,GNPTAB,CSF1,ABCB1,LRRK1,GDF11,TMEM159 |
| 2.572e-05 | -10.57 | MARTINEZ_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_TP53_TARGETS_DN | 560 | 86 | 17758 | 1761 |
TRIM2,KLK10,FAM92A1,EPAS1,ST14,CRYM,THRA,DNAJC3,FHDC1,TP53,PKP2,COL18A1,DDR1,CCND1,APLP2,GRHL1,SIVA1,FRYL,ZFP36,ALDH1A3,SLC44A1,ABCA2,CDH3,RPN2,ECE1,MYH14,TECR,SCARA3,EGLN3,PTPRE,SULT2B1,PLK1,CLCN3,MBP,COL6A2,CENPA,CELSR2,USP18,SNTB2,PANK1,KIF1C,ITPR3,FZD7,OVOL1,AGFG2,TMOD2,UNC5B,SLC25A30,CD99,LASP1,COL9A3,PCOLCE,HJURP,ESRP1,DAP,SOX9,RAB6A,GSTP1,EFNB1,LGALS3BP,FZD6,NEO1,TMCC3,CTNNBIP1,DOPEY2,CALD1,ATP5H,IGFBP2,IGDCC4,NFE2L3,SHMT1,GCLC,ELOVL3,MYBL2,NFIB,FRMD4B,PTPRF,TIMP3,PVRL2,PLOD2,CLIP4,LTBP2,MAP3K5,RARG,SNX30,XDH |
| 2.576e-05 | -10.57 | negative regulation of metabolic process | biological process | GO:0009892 | 2618 | 326 | 16441 | 1675 |
ACACB,TXN,PPP4R4,LGR4,TSC22D3,DNAJC3,PSME1,MORF4L2,CCNB1,BARD1,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,CABP1,RGS3,FOSB,IRF2,CRY2,ZBTB18,TIPARP,APOBEC3G,SMARCA2,TNIP1,PBK,CDA,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,PPP1R14C,POR,AHRR,PIAS3,ENPP1,LIMK1,TRAF3IP1,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,E2F8,LZTS1,CDKN1C,SOX9,RAB23,MECOM,ELF3,MARCH8,TFAP4,PAIP2B,BHLHE41,DAPK1,SORL1,NUP85,SOCS5,SALL4,CALM1,EPHA1,PSMA4,NFIB,PLIN5,FAS,AP1AR,PRKAG2,ETS2,SEMA4D,SFMBT1,NR4A2,STK39,CABIN1,PER3,SERPINB1,NUP58,XDH,EGLN1,SPRED1,NQO1,S100A11,THRA,INPP5D,RPS6KA1,IQGAP1,CAST,PTTG1,BCL2L1,CCND1,APLP2,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,IFIT1,DLG3,CDKN2D,MYT1,NR2C1,CAMSAP3,APOBEC3D,DRAP1,RAD17,PKMYT1,H2AFV,SNX12,NFIX,IRS2,PPP2R5A,CORO1C,WFS1,SLC27A1,KLF5,NRG1,RGS14,CBX7,NKX3-1,TNRC6C,DEPDC1,APOBEC3H,PKN1,GSTP1,TIPRL,FGF19,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,ITGB8,RNF128,PTEN,CST3,BAX,ATP8B1,TMBIM6,WWP1,CITED2,CNOT6L,SPRY2,TRIM62,NCOA2,CRTAP,TGIF1,RAPGEF2,FURIN,GPLD1,CDK5RAP1,PITX2,TIMP3,FGFR2,NR1D2,ACVRL1,TBX18,NR4A3,ITGAV,GPER1,HMGA1,LRRK1,OSR1,CPEB2,JARID2,SIGIRR,CASP3,CRYM,CNOT8,LMCD1,ARFGEF1,NDRG2,F11R,HDAC6,PDGFB,ERP29,SIVA1,PASK,MITF,DLG1,DUSP10,MYBL1,CYP1B1,PLK1,THRB,CD55,KCNIP3,TRIM8,ITCH,CBX6,EZR,PRKRA,OPTN,EDNRA,NEIL1,KLF12,PRKCDBP,KLF11,GLA,LMTK3,RUNX2,PPP1R2,SERPINE2,UBASH3B,DNAJB2,PDCL,CALM3,HES2,FBLN1,IGF1R,GATA2,MDFIC,PIM1,RFX5,ETV7,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,CDK5R1,NUDT16,PLPP3,NFKBIA,SH3BP4,NLRC5,YOD1,JAK3,TOB1,IFI6,RARG,GAS2L1,NF2,FOXM1,PSME2,CTDSPL,TP53,TDRKH,OSR2,SYTL2,IER3,PDGFA,SVBP,SETDB2,BCL6,TWIST1,NOTCH3,CTDSP2,CHP1,PPIF,SIRT1,TIMP2,ERLEC1,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,ARHGAP35,SOCS3,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,STK38,PEX2,OVOL1,PTBP3,TLE1,IRF7,ARFGEF3,GLIS3,ANXA3,SORT1,PINK1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,AIP,FZD6,SH2D4A,HDAC9,CD109,IRF2BPL,FOXP2,TAF1B,ADORA1,BMP7,UBE2J1,TFAP2A,TRIM21,BUB1,IQGAP3,NFE2L3,HES1,RHOA,PSMB4,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,COL7A1,RUNX3,BBS2,LEPR,MAPK8IP1,BANK1,SWAP70,SERPINA1,SPINT2,NMI,ARRB1,SOX8,NDFIP1,UBE2C,HIPK3,AHR,PKIA,ZBTB33 |
| 2.593e-05 | -10.56 | KEGG_PATHWAYS_IN_CANCER | MSigDB lists | KEGG_PATHWAYS_IN_CANCER | 324 | 56 | 17758 | 1761 |
CCNE2,CASP3,NKX3-1,EPAS1,RALBP1,ITGA6,RET,TP53,ERBB2,TGFBR1,BCL2L1,GSTP1,APC2,PDGFB,ETS1,FGF19,FZD6,MECOM,PDGFA,DAPK2,CCND1,ITGA3,IGF1R,CDH1,PTEN,PLCG2,MITF,DAPK1,PIK3CA,BAX,CDKN1B,PIK3CD,WNT3A,EGLN3,DVL2,RHOA,AKT1,FZD4,PIK3R1,CASP9,TCF7,FOS,FZD7,FAS,PGF,PIAS3,PLCG1,JAK1,FGFR2,NFKBIA,HDAC1,ITGAV,PLD1,FZD5,TRAF5,EGLN1 |
| 2.597e-05 | -10.56 | negative regulation of molecular function | biological process | GO:0044092 | 1054 | 148 | 16441 | 1675 |
SIGIRR,CASP3,PPP4R4,DNAJC3,ARFGEF1,F11R,PSME1,HDAC6,PDGFB,CALM2,CDKN2C,PSMD1,CABP1,SIVA1,RGS3,DUSP10,CRY2,CYP1B1,ZNF462,PLK1,ITCH,PRKAR2B,PIF1,PPP1R14C,POR,NEIL1,LIMK1,NOD2,CAB39,SERPINB6,SERPINI1,GLA,HSPB1,LMTK3,PPP1R2,CDKN1C,SERPINE2,UBASH3B,CALM3,TFAP4,IGF1R,NEK2,SORL1,PIM1,MDFI,SOCS5,EPB41L5,CALM1,EPHA1,PSMA4,NFIB,PLIN5,FAS,PTPRF,PRKAG2,SEMA4D,NFKBIA,SH3BP4,NLRC5,AURKA,STK39,CABIN1,SERPINB1,IFI6,EGLN1,SPRED1,NQO1,NF2,THRA,RPS6KA1,IQGAP1,PSME2,CAST,PTTG1,TP53,SYTL2,APLP2,SP100,CDKN1B,DAB2IP,TWIST1,IFIT1,DLG3,CDKN2D,CHP1,SIRT1,PPIF,CAMSAP3,TIMP2,AKT1,CDC20,PKMYT1,ERBB2IP,DUSP4,SOCS3,IRS2,PTPRJ,PPP2R5A,STK38,WFS1,CORO1C,RGS14,ARFGEF3,ANXA3,NKX3-1,SORT1,DAP,HABP4,PSMD10,AES,ANO9,PKN1,TRIB2,GSTP1,AIP,TIPRL,SH2D4A,FZD6,WWP2,CD109,CTNNBIP1,GNB5,PTEN,BMP7,CST3,BAX,TRIM21,TMBIM6,ADAM15,BUB1,SPRY2,PSMB4,PLAUR,FURIN,PPARA,COL7A1,LEPR,MAPK8IP1,CDK5RAP1,TIMP3,SERPINA1,SPINT2,ARRB1,UBE2C,NDFIP1,CPEB2,HIPK3,PKIA |
| 2.620e-05 | -10.55 | carbohydrate metabolic process | biological process | GO:0005975 | 829 | 121 | 16441 | 1675 |
SLC35D2,GAA,SLC2A4,UGT8,PAPSS2,HSPG2,UGP2,GNPDA1,GALNT12,SLC25A13,HEXB,NANS,MGAT5B,PRKACA,SDC1,CHPF,CALM2,MUC16,MUC4,IL6ST,IMPAD1,PAPSS1,PIK3CA,FUT1,AKR1B1,GOT1,RPN2,GLB1L2,LMAN1,PHKA2,TIPARP,MGAT5,NAGA,GM2A,CHP1,SIRT1,SEC23A,AKT1,SLC35C1,GLO1,GALNT7,MCFD2,IDH1,ARF4,IRS2,MAN2A2,HS6ST1,ALDH5A1,HPSE,DDOST,UEVLD,DOLPP1,GNPTAB,DHTKD1,HS3ST3B1,GLA,ITPKA,ST3GAL1,MAN2B2,CMAS,PPP1R2,ENO2,GNE,SDC4,CALM3,PDIA3,CTSZ,ISYNA1,B4GALT4,DSE,POMGNT1,ADAMTSL4,KIAA1161,B4GALNT1,GNS,B3GALNT1,FUT2,CTSC,PTEN,A4GALT,MGAT4A,ALG13,GALNS,FUT8,UBE2J1,PPP6R1,NUP85,GCNT1,TRAK2,HMMR,CHSY3,GFPT1,B3GALT6,PGM1,B3GNT7,ALDH2,B3GNT2,GUSB,GCLC,CALM1,MGAT4B,GYLTL1B,PARP4,OGDHL,C1GALT1C1,COL7A1,PDK3,GLT8D2,CYB5A,GLCE,GALNT3,FUCA1,ONECUT1,PRKAG2,UAP1,SERPINA1,PGM2L1,MDH1,CTSA,ARSB,NUP58 |
| 2.632e-05 | -10.55 | SWEET_LUNG_CANCER_KRAS_UP | MSigDB lists | SWEET_LUNG_CANCER_KRAS_UP | 472 | 75 | 17758 | 1761 |
SLC2A4,AVPI1,AASS,IQGAP1,COL18A1,IL18,PSME1,ITPR2,SDC1,CA8,PHLDA1,TNFSF9,CCND1,EPCAM,SIVA1,ELF5,TACSTD2,MANF,ACSL4,SNX10,CKS2,SAT1,ATP1B1,SLC25A5,SOCS3,ATP1A1,KCNK1,AXL,KLF5,ARF6,RAP1GAP,TM2D2,SERPINE2,LGALS3,CHCHD7,CD63,ESRP1,DAP,GNE,AES,CTSZ,NUCB2,SIRPA,PARM1,B4GALNT1,GNS,CTSC,RRBP1,CD9,PCYOX1,OSTF1,MDFIC,CITED2,SLC12A2,KDELR1,MDFI,WBP5,TGIF1,SHMT1,CRB3,LITAF,PIP4K2C,PDK3,NPC2,PRDX4,GALNT3,FUCA1,PTPRF,SLC4A4,TMEM30A,CLIP4,FAM117A,CTSA,TOB1,EHD1 |
| 2.646e-05 | -10.54 | Signaling by SCF-KIT | REACTOME pathways | R-HSA-1433557 | 307 | 56 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,TEC,PHLPP1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,PTPRU,NR4A1,RAPGEF2,PIK3R1,CASP9,CALM1,GRIN1,AGO4,YES1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,PHLPP2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 2.648e-05 | -10.54 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 409 | 67 | 17758 | 1761 |
LMO7,ACACB,SORBS1,PAPSS2,IL15RA,DLGAP5,NQO1,ATP8A1,TSC22D3,COL18A1,NDRG2,PHLDA1,EMP2,RPS6KA2,METTL7A,ZFP36,MITF,KCNS3,SEMA3G,MYBL1,CYP1B1,MX1,ING1,CAPN6,ARHGDIB,PRKAR2B,LOXL2,MCFD2,ALCAM,CDK1,HLF,POPDC3,KLF11,CDKN1C,SERPINE2,GDF15,COL4A5,SEPP1,ANO1,SRPX2,TOP2A,KIF13B,BAX,CD9,LIMCH1,KLF9,MYLIP,SPRY2,IGSF3,GFPT1,CYP26B1,ASPM,PIK3R1,SPTLC2,NFIB,CD83,FRMD4B,ETS2,NFKBIA,MATN2,ERAP1,CLMN,FAM117A,GEM,PER3,IFIH1,MELK |
| 2.735e-05 | -10.51 | TGANTCA_V$AP1_C | MSigDB lists | TGANTCA_V$AP1_C | 1074 | 147 | 17758 | 1761 |
HSPG2,CAMKK1,FBXO2,NDRG2,LYNX1,MPP5,LTBP3,NCS1,SLC9A7,HTR1D,CDKN2C,BTG3,PSMD1,SHC3,RGS3,MITF,ABCA2,SERINC2,AKR1B1,CLDN4,NTN4,TINAGL1,MYH14,TLN2,THRB,ATL1,SMARCA2,TRIM8,MCTP1,RGAG1,TMEM151A,ZFAND5,TYSND1,TRIM9,MAP2,KCNK1,PRKCDBP,CAB39,SEMA6B,SCN5A,SCOC,LGALS3,LRRFIP2,NUAK1,ETV5,CALB2,CNTNAP2,FAM81A,DHRS3,S100A2,HPCAL4,PRRG4,LMNA,MECOM,SLC16A6,VASN,RPL39,KCNN4,TNFRSF12A,PIM1,IGSF3,MDFI,ELK3,PIP4K2C,EPHA1,SPTLC2,GLT8D2,PRX,EPN3,S100A5,AGBL5,DRP2,COL16A1,TOB1,XDH,PROM2,SPRED1,SLC25A24,XYLT1,PRSS22,RNF182,FAM198B,DDR1,REPS1,ZFYVE9,ZNF385B,FAM46A,LMO4,VAT1,PDE4D,ACSL4,RAB27B,ETV4,SNX10,SEMA3B,DOCK4,CAPN6,PTPRU,SAT1,IGSF8,ATP1B1,C15orf39,MAP3K6,GABARAPL1,POPDC3,SIPA1L1,ADAMTS14,KLF5,NRG1,HS3ST3B1,REEP4,COBL,MAPK12,CTHRC1,CMAS,IGFBP6,ENO2,KLHL13,PKN1,SPR,GSTP1,SRPX2,NRP2,HDAC9,CD109,IGSF9,SGK3,GTF2F2,SGK1,ADAM15,ABCD1,TAGLN2,KLF9,CNOT6L,NFE2L3,TGIF1,ARAP2,LONRF3,CRB3,FURIN,COL7A1,AIF1L,OTUB2,FAM117A,HMGA1,UBE2C,SNPH |
| 2.754e-05 | -10.50 | RYTTCCTG_V$ETS2_B | MSigDB lists | RYTTCCTG_V$ETS2_B | 1031 | 142 | 17758 | 1761 |
SIGIRR,SSH1,DHX8,ITPR2,PDGFB,CMTM6,LTBP3,SH3KBP1,SESN3,SHC3,STIM1,RGS3,OSBPL3,SERINC2,ABCA2,POF1B,PIK3CD,CITED4,SH3BGRL,SLC35C1,ARHGDIB,LDB2,SLC25A5,ZBTB7B,SPNS3,ARF4,ABR,TMEM164,ENPP1,PLCG1,KLF12,MADD,CAB39,SP6,SERPINI1,ARF6,NFKBIE,RASA2,ETV5,NDUFA4,B4GALNT1,RINL,ZNRF2,KCNN4,ATP5H,FXYD5,PLCB2,MYLIP,RIMS2,CCDC88A,C9orf9,B3GNT7,PCDH1,ELK3,STAT4,HMG20B,DGKH,MAPKAPK2,EPN3,PRKAG2,PLEKHH2,DCK,ITPR1,AGBL5,SH3BP4,EGFL7,NR4A2,CTSA,ARPC2,DRP2,JAK3,TRIP10,PSME2,CAST,FTH1,PRKACA,EPS8L2,SS18,ZNF687,SH3BP1,LMO4,BCL6,SRR,CNNM4,DIXDC1,DAB2IP,PDE4D,SCN2A,SCN3A,FRS3,PPIF,DOCK4,CLCN3,ERBB2IP,DUSP4,ITPR3,CD40,ATP13A2,CCDC149,PTK7,RGS14,BIN1,CMAS,FBLIM1,CYB561,TRMT2B,ETS1,FZD6,TEAD3,WWP2,M6PR,RNF128,LLGL2,ARSG,PTEN,MGAT4A,BMP7,CALD1,SGK1,ADAM15,KLF9,TAGLN2,CITED2,RBMS2,TGIF1,PGM1,AMFR,PIK3R1,FURIN,RUNX3,LRRC1,PITX2,FGFR2,RAP2C,NR4A3,OTUB2,HMGA1,FHL1,DEF6,ZBTB33,ARHGEF4,TLL2 |
| 2.833e-05 | -10.47 | MITSIADES_RESPONSE_TO_APLIDIN_DN | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_DN | 243 | 45 | 17758 | 1761 |
NF2,ENO2,ZNF395,DLGAP5,HJURP,FOXM1,CKAP2,IQGAP1,ATP8A1,PTTG1,CDCA8,CALM3,KCTD12,TEX2,CCNB1,LBR,FANCI,HDAC9,CALM2,TOP2A,WEE1,ADD3,KIF14,FAM20B,FUT8,NEK2,CD9,BUB1,AHCY,SYK,GPR161,ZWINT,CENPA,MMD,ASPM,CALM1,MYBL2,NUSAP1,DCP2,ANKRD10,ALDH5A1,AGBL5,AURKA,NCAPG2,MELK |
| 2.839e-05 | -10.47 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 505 | 79 | 17758 | 1761 |
LAMP1,LZTFL1,SLC35D2,SORBS1,LMCD1,TGOLN2,ERP29,PHLDA1,CMTM6,CCND1,SS18,DPYSL2,TSPAN6,DLG1,PIK3CA,KCNS3,PDE4D,TIPARP,CTDSP2,CTH,GCA,NFE2L1,DAG1,ARF4,GABARAPL1,DDOST,AGPAT2,RAB11FIP1,KLF5,SERPINB6,SERPINI1,KLF11,LTA4H,CBX7,RRAGD,RMND5A,ALDH6A1,PEX6,SDC4,ETV5,SOX9,ASAH1,GSTP1,AIP,H1FX,SIRPA,NRP2,FZD6,HDAC9,WWP2,SLC25A36,M6PR,CTNNBIP1,ADD3,PTEN,TFAP2A,CADPS2,ERBB3,SPRY2,CRTAP,GPR161,PDGFC,RHOA,PLSCR1,TESK1,SYBU,PIK3R1,LRRC1,NFIB,CD83,GLCE,GNAS,SCARB2,TIMP3,PLOD2,PRCP,MATN2,NR4A3,SLC25A38 |
| 2.844e-05 | -10.47 | human chrXq22.1 | chromosome location | human chrXq22.1 | 30 | 10 | 26250 | 1887 |
XKRX,ARMCX3,TIMM8A,CENPI,PCDH19,CSTF2,TRMT2B,TCEAL8,SRPX2,LINC00630 |
| 2.864e-05 | -10.46 | chordate embryonic development | biological process | GO:0043009 | 595 | 92 | 16441 | 1675 |
EMX1,GRHL2,ADD1,HSPG2,HOXB7,EPAS1,ST14,TP53,OSR2,BCL2L1,CCNB1,PRKACA,STIL,PDGFB,RCN1,LMO4,DLG1,PLK4,TWIST1,ECE1,ZBTB18,DVL2,SULF2,SPEF2,AKT1,TFAP2C,ICMT,ZFAND5,EDNRA,ARHGAP35,SOCS3,HS6ST1,PLCG1,SHROOM3,PTK7,HOXA9,TRAF3IP1,TANC2,E2F8,GAB1,COBL,MAFF,PCSK5,GRN,CTHRC1,RUNX2,NKX3-1,CDKN1C,SDC4,RAB23,TGFBR1,NCKAP1,HOXB2,SIX4,PPP2R3A,FZD6,ELF3,MECOM,E2F7,CYR61,GATA2,BMP7,MEGF8,FUT8,NEK2,TFAP2A,WNT3A,MDFI,EPB41L5,TGIF1,HES1,SALL4,UBE2A,PRICKLE1,VEZT,SCRIB,G2E3,GNAS,NCOA3,FGFR2,ACVRL1,SPINT2,TBX18,PLOD3,FZD5,ZMIZ1,SOX8,OSR1,NCAPG2,CCNB2,RARG,EGLN1 |
| 2.876e-05 | -10.46 | blood vessel development | biological process | GO:0001568 | 438 | 72 | 16441 | 1675 |
HSPG2,EPAS1,FOXM1,COL18A1,IL18,VASH1,PDGFB,PDGFA,TYMP,NOV,CTGF,PIK3CA,DAB2IP,EPHB4,NOTCH3,TIPARP,CYP1B1,MAP3K3,SIRT1,AKT1,FZD4,SAT1,HTATIP2,LOXL2,EDNRA,SOCS3,PGF,HS6ST1,PTPRJ,HPSE,PNPLA6,KLF5,UNC5B,E2F8,NKX3-1,ADGRG1,TGFBR1,ETS1,SRPX2,NRP2,SGPL1,E2F7,ITGB8,PTEN,CYR61,BAX,ADAM15,TNFRSF12A,MYDGF,SYK,HES1,ELK3,NR4A1,RAPGEF2,EPHA1,RASA1,GPLD1,ARHGAP24,ACVRL1,SCG2,FGFR2,PRCP,PLPP3,ITGA7,ERAP1,EGFL7,HOXB13,ITGAV,ZMIZ1,OSR1,FZD5,AHR |
| 2.877e-05 | -10.46 | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 172 | 35 | 17758 | 1761 |
DLGAP5,CENPI,PTTG1,PDIA5,C5orf30,DNAJB11,NUF2,CCNB1,SDC1,STIL,PARM1,BHLHE41,SLC44A1,UBE2J1,BUB1,RPN2,MANF,LMAN1,FAIM,HMMR,SEC61B,ERLEC1,PBK,CDC20,C3orf52,GGH,TXNDC11,CDK1,GPLD1,PRDX4,SLC25A4,CCNB2,GLCCI1,E2F8,DENND5B |
| 2.899e-05 | -10.45 | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | MSigDB lists | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | 87 | 22 | 17758 | 1761 |
CD99,HES1,TRIM2,HLA-E,AK4,RUNX3,RNF113A,FOS,STEAP1,SIRPA,GABARAPL1,GLCE,MAN2A2,CCND1,ATP1A1,UAP1,JAK1,DPYSL2,DAPK1,NPTXR,CITED2,RAP1GAP |
| 2.901e-05 | -10.45 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | 193 | 38 | 17758 | 1761 |
GRN,PLA2G4A,SORT1,TXN,IGFBP6,PSME2,BLVRB,ERI2,DSE,SPR,DHRS3,TSEN34,RCN1,TNS3,ATP6V0B,LMO4,AIM1,RAB20,SNX10,S100A13,CKAP4,CPD,PLAUR,CDA,HMG20B,IFIT3,DAG1,STX3,ABR,DNM1L,P4HA2,SECTM1,SLC2A6,NETO2,IRF7,ATP1B3,GEM,SLC27A3 |
| 2.901e-05 | -10.45 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | 179 | 36 | 17758 | 1761 |
DDX58,CDK17,TTC39B,IL15RA,IL15,HERC5,CD274,HERC6,PLS3,DTX3L,ITGB8,GRHL1,DRAM1,MAPK11,IFIT1,ETV7,APOBEC3G,CKAP4,PARP9,MX1,MICB,USP18,NUB1,PTGER4,IFIT3,SOCS3,CACHD1,TRIM69,NLRC5,NR4A3,IRF7,NFKBIZ,HS3ST3B1,CMPK2,IFIH1,MELK |
| 2.909e-05 | -10.45 | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | 186 | 37 | 17758 | 1761 |
SIGIRR,HECA,HAPLN3,GALNT12,EPHA4,MORC4,AES,CD274,TRIB2,TMEM63A,ITGA3,TOX2,ANKRD12,WWP1,MAST4,TRIM62,ABCC1,SUSD3,PRKCQ,TCF7,ITPR3,OPTN,PLCG1,TJP3,COQ10A,AMMECR1,LRIG1,FAM117A,AGFG2,PIEZO1,TBC1D4,TMEM14A,HSPB1,CBX7,TMEM173,EHD1,DOCK9 |
| 2.911e-05 | -10.44 | ATP binding | molecular function | GO:0005524 | 1456 | 194 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ENPP1,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,KIF23,TEC,MERTK,BMP2K,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,STK17A,DHX32,DGKH,MAPKAPK2,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,SCYL3,SEPHS1,MYO5B,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,PANK1,KIF1C,PRKCQ,ATP1B1,PKMYT1,RAD17,MAP3K6,ATP10D,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,TGFBR1,PKN1,DNAH3,KIF5B,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,UBE2J1,SGK3,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,MYO5A,ATP2B1,OPLAH,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,FGFR2,ACVRL1,ABCB1,RYK,LRRK1,CENPE,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 2.921e-05 | -10.44 | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | 81 | 21 | 17758 | 1761 |
PPIF,CASP3,ZWINT,SERPINE2,DLGAP5,BLVRB,CDC20,NUSAP1,PRKAR2B,KIF11,CDK1,LEPR,LMNA,SAC3D1,APOBEC3B,TOP2A,CA2,AMMECR1,MINPP1,CCNB2,MELK |
| 2.922e-05 | -10.44 | angiogenesis | biological process | GO:0001525 | 295 | 53 | 16441 | 1675 |
HSPG2,EPAS1,ADGRG1,COL18A1,IL18,TGFBR1,VASH1,ETS1,SRPX2,NRP2,PDGFA,E2F7,NOV,TYMP,CTGF,PTEN,CYR61,PIK3CA,BAX,ADAM15,DAB2IP,TNFRSF12A,EPHB4,MYDGF,NOTCH3,SYK,CYP1B1,SIRT1,ELK3,NR4A1,SAT1,HTATIP2,EPHA1,LOXL2,EDNRA,GPLD1,PGF,ARHGAP24,HS6ST1,HPSE,ACVRL1,SCG2,FGFR2,PRCP,PNPLA6,ERAP1,EGFL7,KLF5,HOXB13,ITGAV,UNC5B,FZD5,E2F8 |
| 2.932e-05 | -10.44 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | 125 | 28 | 17758 | 1761 |
TGIF1,TIMP2,ZWINT,TNIP1,PRSS23,LGALS3,PLSCR1,NFE2L1,SLC11A2,RNF19B,B4GALNT1,MAPKAPK2,ST5,TIMP3,PLK2,CSF1,NFKBIA,BAX,CLDN4,KLF5,TACSTD2,NFKBIZ,TAGLN2,RELL1,ERBB3,S100A13,GAB1,OCLN |
| 2.960e-05 | -10.43 | regulation of membrane lipid distribution | biological process | GO:0097035 | 36 | 13 | 16441 | 1675 |
PLSCR1,KCNN4,ATP8A1,ATP9A,TMEM30A,ANO6,ATP8B1,ATP8B3,ANO9,ANO4,ABCA1,ATP10D,XKR8 |
| 2.960e-05 | -10.43 | CTNNB1 (catenin (cadherin-associated protein), beta 1) | protein interactions | 1499 | 315 | 58 | 16036 | 1726 |
CASP3,NF2,EPAS1,TRIP10,CD82,IQGAP1,PKP2,ERBB2,HERC5,TGFBR1,HDAC6,APC2,ZFYVE9,LMNA,TOP2A,CTNNBIP1,CCND1,RNF220,CDH1,PTEN,MITF,TFAP2A,NEK2,BCL6,SGK1,CDH3,IGFBP2,NCOA2,DVL2,DLGAP1,PLK1,SIRT1,AKT1,PTPRU,NR4A1,BCL9,RAPGEF2,PIK3R1,AMER1,GRIN1,EZR,VEZT,PYGO1,ERBB2IP,CDK5R1,FAS,PTPRF,JADE1,PITX2,PTPRJ,RYK,TLE1,HDAC1,GRIN2D,KLF5,AHR,TOB1,ZBTB33 |
| 2.963e-05 | -10.43 | MODULE_451 | MSigDB lists | MODULE_451 | 32 | 12 | 17758 | 1761 |
TOP2A,PLK1,SORT1,CENPA,PTK7,ESRP1,CDC20,MYBL2,NEK2,CCNB1,CDK1,MELK |
| 2.992e-05 | -10.42 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 318 | 55 | 17758 | 1761 |
LRRFIP2,GNE,ERI2,MORC4,COL18A1,EFHD2,CYB561,PSME1,TEX2,OAT,DDR1,SGPL1,HSF2,SLC27A6,FRY,FRYL,LMO4,TBCD,DAPK1,TFAP2A,CDH3,DIXDC1,MYLIP,FAM69A,CPD,SUN2,GCA,CLCN3,CAPN6,COG2,PBK,SYNE2,ACO1,FBXO9,PRKAR2B,SESN1,DAG1,POR,PTPRF,AMZ2,FAM64A,POPDC3,FGFR2,SLC9A6,SPINT2,PPM1H,ARRB1,COBL,ACOT7,KLF7,JARID2,ABCG1,RRAGD,DOCK9,ARHGEF4 |
| 2.998e-05 | -10.41 | oesophagus | COSMIC cancer mutations | oesophagus | 15768 | 1608 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,XRCC6BP1,ZNF618,COX20,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,CXorf57,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TSPAN18,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,DNAH3,EFNB1,FGF19,WWP2,SLC25A36,SCML1,E2F7,TMEM87B,RNF128,FUT8,FJX1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,MAN2A2,HPSE,KCNK1,MADD,ZNF165,SP6,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,HMGA1,USF2,DCBLD1,CYBRD1,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,CCNF,SAV1,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,ALPK3,RHOBTB2,PITPNA,EGFL7,PROM2,KLF7,SLC25A24,SPC25,FAM92A1,IL15,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 2.999e-05 | -10.41 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | 538 | 83 | 17758 | 1761 |
TRIM2,UGT8,CRYM,PSME2,ATP8A1,RALBP1,SLC25A13,ARFGEF1,MORF4L2,OAT,PJA2,BCAP31,CDS1,PLS3,APLP2,WEE1,DPYSL2,IL6ST,PAPSS1,VAT1,GOT1,ACSL4,MINPP1,F2R,BTBD3,CYP1B1,LAMP2,SEC23A,SH3BGRL,SEPT6,CBX6,PRKRA,H2AFV,IDH1,CASP4,ARF4,TAPBP,DDOST,ARF6,F2RL1,LASP1,SERPINE2,PPP1R2,HLA-F,EPS8,PDIA3,HMGN3,GTF3A,BMP2K,HLA-A,ADD3,IGF1R,CD9,WWP1,ERBB3,CITED2,NCOA2,SYPL1,PGM1,RHOA,PLSCR1,LPGAT1,LITAF,FBXO9,AK4,FNDC3A,PSMA4,FRMD4B,PRDX4,FECH,NCOA3,SWAP70,ACADSB,PLOD2,NR1D2,HNRNPH2,NMI,TCEAL4,RYK,MDH1,FHL1,TOB1,AHR |
| 3.053e-05 | -10.40 | vasculature development | biological process | GO:0001944 | 462 | 75 | 16441 | 1675 |
HSPG2,EPAS1,FOXM1,COL18A1,IL18,VASH1,PDGFB,PDGFA,TYMP,NOV,CTGF,PIK3CA,DAB2IP,EPHB4,NOTCH3,TIPARP,CYP1B1,MAP3K3,SIRT1,SMARCA2,AKT1,FZD4,SAT1,HTATIP2,LOXL2,ZFAND5,EDNRA,SOCS3,PGF,HS6ST1,PTPRJ,HPSE,PNPLA6,KLF5,UNC5B,E2F8,NKX3-1,ADGRG1,TGFBR1,ETS1,SRPX2,NRP2,SGPL1,E2F7,ITGB8,PTEN,CYR61,BAX,ADAM15,TNFRSF12A,MYDGF,SGCB,SYK,HES1,ELK3,NR4A1,RAPGEF2,EPHA1,RASA1,GPLD1,ARHGAP24,ACVRL1,SCG2,FGFR2,PRCP,PLPP3,ITGA7,ERAP1,EGFL7,HOXB13,ITGAV,ZMIZ1,OSR1,FZD5,AHR |
| 3.058e-05 | -10.40 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 403 | 66 | 17758 | 1761 |
CCNE2,KLK10,ST14,MRAS,F11R,TP53I11,BARD1,IER3,DOK4,MKRN3,CABP1,LHX6,ELF5,DUSP10,CDH3,TWIST1,TACSTD2,ESPN,SCARA3,CYP1B1,MX1,SMARCA2,CD55,CYB5R2,CDA,TFAP2C,RAB38,PGF,HOXA9,ZNF165,IRF7,EPB41L4A,NRGN,HOXC13,NXT2,MRC2,CDKN1C,ZCCHC24,GDF15,RAB6A,SAMD9,CRABP2,S100A2,DIRAS3,ADRBK1,LYPD3,TPST1,DAPK1,TMEM51,HLA-C,ULBP2,CYP26B1,PLAUR,MBNL3,SNTB1,HLA-B,TIMP3,SERPINA1,CSF1,ITGA7,NETO2,RHOBTB2,IFIH1,AHR,IFI6,ARHGEF4 |
| 3.107e-05 | -10.38 | epithelial tube morphogenesis | biological process | GO:0060562 | 303 | 54 | 16441 | 1675 |
CTHRC1,NKX3-1,GRHL2,LGR4,ST14,EPHA4,SOX9,SDC4,RET,RAB23,CTSZ,NCKAP1,PRKACA,STIL,FZD6,CTNNBIP1,SETDB2,NPNT,BMP7,LMO4,MEGF8,DLG1,BAX,TWIST1,TACSTD2,WNT3A,SLC12A2,ETV4,SPRY2,DVL2,HES1,TGIF1,FMN1,SALL4,TFAP2C,PRICKLE1,SCRIB,NPHP3,DAG1,EDNRA,ARHGAP35,NCOA3,FAT4,ACVRL1,SHROOM3,FGFR2,PTK7,CSF1,SPINT2,SOX8,OSR1,COBL,RARG,ADAMTS16 |
| 3.123e-05 | -10.37 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3776 | 440 | 17775 | 1757 |
SLC35D2,PPP4R4,LGR4,HSPG2,AASS,VANGL1,SLC25A13,ATP8A1,DNAJC3,RET,CACNA2D2,NRG2,VASH1,GRM5,CALM2,CDKN2C,DAPK2,TYMP,SESN3,PSMD1,ZNF823,ELMO2,STIM1,SERINC2,PIK3CA,ATRNL1,PIK3CD,TIAM1,ERAP2,ORAI2,SPEF2,LOC81691,SNTB2,SH3BGRL,HSPA12A,CASP9,CDA,TFAP2C,PRKAR2B,LOXL2,GALNT7,LDB2,PPP1R14C,CCNF,COL12A1,ANKRD10,PLCG1,LIMK1,NOD2,PRDM5,BMP1,HDAC1,NFKBIZ,EIF4EBP2,TANC2,GAB1,DDX58,CDK17,FRMD4A,FAM169A,TBC1D1,C6orf106,SLC36A4,GPSM2,MERTK,TNFRSF19,PRRG4,ATG4A,MARCH8,DOPEY2,RALGPS2,FRY,ITGA3,LYPD3,PIK3AP1,FAM189A1,RIMS3,BDH1,RUNDC3B,PRKG1,MAP3K9,SORL1,CD70,CADPS2,OSTF1,CACNA1D,PIKFYVE,NCAM1,MYLIP,DGKG,NUP85,MCCC2,GPR161,FAM69A,TRAK2,EPB41L5,GFPT1,LPGAT1,STAT4,MYBL2,ANTXR1,PCTP,NFIB,DCP2,CYB5A,STX3,RASA1,FAS,STK17A,DHX32,PTPRF,DGKH,CACHD1,NCOA3,PRKAG2,PLEKHH2,TJP3,FAAH,ISM1,PELI2,ITPR1,PCDH19,SFMBT1,MAP3K5,PER3,HOOK1,IFIH1,XDH,EGLN1,EHD1,DOCK9,PLA2G4A,FRMPD3,SPRED1,SLC2A4,GRHL2,DLGAP5,PAPSS2,ST14,S100A11,ACTR8,CCDC110,RPS6KA1,IQGAP1,ATP2C2,TESK2,PKP2,APC2,MNS1,CYP39A1,REPS1,ZFYVE9,ZNF385B,APPBP2,CDS1,NOV,RNF220,CDH1,IFIT1,EPHB4,PHKA2,NR2C1,SCN3A,MYO5B,SEC23A,CAPN6,PTPN9,SYNE2,PANK1,UTRN,TMEM144,CDCA2,PRKCQ,RAB38,NIN,PRDM11,EPHA10,IRS2,SHROOM3,CDK19,SIPA1L1,INPP4B,ZNF704,PLEKHG1,NRG1,NR3C2,COBL,DENND5B,TTC8,WASF3,ATP9A,CENPI,HABP4,EPS8,SDC4,PBX3,ANO9,PKN1,PLPPR4,ETS1,LGALS3BP,NEO1,WWP2,PDIA4,SLC27A6,RNF128,ANKS1B,CTSC,PTEN,FAM20B,FUT8,KLC3,WWP1,ERBB3,NPTXR,NCOA2,FARP2,ADAMTS2,RASGRF1,PDGFC,ARHGEF28,ARAP2,PLSCR1,ZC3H11A,TACC1,RAPGEF2,PIK3R1,EIF5A2,DIAPH2,LRRC1,SNTB1,ARSK,GPLD1,CNTNAP1,RPL12,PLOD2,SYT7,NR1D2,TBX18,ABCB1,PPM1H,GRIN2D,ITGAV,ARSB,ESPL1,DCBLD1,OCLN,TLL2,JARID2,LTBP1,BCAM,EPAS1,EPHA4,CUL4B,LMCD1,ITPR2,SDC1,DNER,TMC1,TRIM68,SH3KBP1,NKAIN3,SIPA1L2,HSF2,ARHGEF37,SHC3,IMPAD1,TSPAN6,PAPSS1,MITF,ANKFN1,DLG1,DUSP10,POF1B,TRPC1,SUN3,RAB20,ANO4,TLN2,MYRIP,BTBD3,MYBL1,TRAM1,S100A13,SMAGP,ZNF462,THRB,MCTP1,KCNIP3,CELSR2,ITCH,ROR1,ANLN,IDH1,EDNRA,DPYSL3,KLF12,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,RRAGD,NR2C2,FXYD3,ABCG2,RAB6A,CNTNAP2,NCKAP1,SAMD9,B4GALT4,PHLPP1,TNS3,IGF1R,FRAS1,MDFIC,LIMCH1,PIM1,HLA-C,WNT3A,SLC12A2,GAD1,ABCC1,CHSY3,ELK3,PCDH1,CORO2A,SPATA13,PDE5A,HEATR5A,IFIT3,NUBP1,PDIK1L,ANKRD29,XKRX,ONECUT1,TMEM30A,P4HA3,ALPK3,PLD1,SEMA3A,JAK3,USP43,KLF7,LMO7,NCKAP5,PSME2,CTDSPL,TMX4,XYLT1,TP53,PDIA5,ERBB2,MRAS,STIL,TTC21B,LMO4,FRYL,PLCG2,BCL6,CDH3,GLB1L2,RPN2,EPB41L4B,NOTCH3,SULF2,MAP3K3,TMTC1,ZNF525,CLCN3,MBP,AKT1,DOCK5,DAG1,IDE,ABHD12,PTK7,ADAMTS14,TLE1,VSIG10,SPTBN5,EFNA5,NDST3,LNP1,LIFR,CMTM4,BIN1,SORT1,GOLIM4,CDH22,ARHGEF11,GABRG2,TRMT2B,DSE,FAM167A,SLC9A2,NRP2,FZD6,SH2D4A,TMEM63A,ZDHHC21,CD109,KIF5B,IL17RB,MLPH,BMP7,TOX2,RRBP1,UBE2J1,KIAA0319,SGK1,BUB1,MYO5A,IGDCC4,NFE2L3,DLGAP1,PGM1,RHOA,NR3C1,ASPM,OGDHL,MBNL3,TTC7A,MAML2,PELI3,FNDC3A,TXNDC11,DGKE,CD83,KLHL2,BANK1,SWAP70,FAT4,RND3,SH3BGRL2,TBC1D4,PTGES,HIPK3,AHR,RAB3IL1,ARHGEF4 |
| 3.137e-05 | -10.37 | SWEET_LUNG_CANCER_KRAS_DN | MSigDB lists | SWEET_LUNG_CANCER_KRAS_DN | 419 | 68 | 17758 | 1761 |
MYL9,SORBS1,PAPSS2,EPAS1,ARFGEF1,NDRG2,KCTD12,IL27RA,EMP2,FAM46C,RCN1,ST5,NPNT,TSPAN6,CYP2S1,IL6ST,TIAM1,SMARCA2,COL6A2,USP18,SESN1,ANKRD10,PRKCDBP,LIFR,ABCA1,ARHGEF3,CDKN1C,IGFBP6,TNFRSF19,ETS1,PSIP1,TSPAN7,RABGGTA,TOP2A,CA2,CYR61,IGFBP2,ALDH7A1,TSPAN13,LIMCH1,BUB1,KLF9,ABCC1,IFITM3,PIP4K2C,STMN3,GGH,IFIT3,NFIB,C3orf58,LEPR,PRX,FAS,TIMP3,ETS2,COL13A1,ACVRL1,TWSG1,NFKBIA,MATN2,PGRMC1,ARRB1,FHL1,IFIH1,PTGES,AHR,PKIA,KLF7 |
| 3.150e-05 | -10.37 | REACTOME_DEVELOPMENTAL_BIOLOGY | MSigDB lists | REACTOME_DEVELOPMENTAL_BIOLOGY | 380 | 63 | 17758 | 1761 |
MYL9,COL9A3,SCN5A,SLC2A4,ARHGEF11,RPS6KA1,ERBB2,COL4A5,PLXNA1,CACNB4,SPTB,NRP2,NEO1,RPS6KA2,ARTN,DPYSL2,COL6A1,DLG1,MAPK11,NTN4,MYH14,SCN2A,NCAM1,DLG3,MED30,NCOA2,MED22,FARP2,DPYSL5,HES1,COL6A2,RHOA,AKT1,RGMB,ACVR1C,DRAP1,FURIN,PPARA,EZR,PRKCQ,ALCAM,CDK1,RANBP9,CDK5R1,DPYSL3,ARHGAP35,CNTNAP1,ONECUT1,NCOA3,PLCG1,SEMA4D,CDK19,LIMK1,PITPNA,KLF5,SPTBN5,ITGAV,UNC5B,SEMA3A,L1CAM,MYL12B,MAPK12,RGMA |
| 3.242e-05 | -10.34 | Endosomal/Vacuolar pathway | REACTOME pathways | R-HSA-1236977 | 11 | 7 | 8202 | 867 |
CTSL,HLA-B,HLA-C,HLA-E,HLA-F,CTSV,HLA-A |
| 3.243e-05 | -10.34 | MODULE_100 | MSigDB lists | MODULE_100 | 523 | 81 | 17758 | 1761 |
TRIM2,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,APC2,PHLDA1,CABP1,LMO4,ALDH1A3,IFIT1,BTBD3,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,TLE1,SERPINI1,ITPKA,NRGN,BIN1,WASF3,COL9A3,CDH22,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,CALB2,SOX9,GABRG2,SLC1A3,CNTNAP2,SEPP1,TSPAN7,PARM1,ELF3,NEO1,DIRAS3,CA2,RIMS3,IGFBP2,ALDH7A1,NCAM1,GAD1,RIMS2,FADS2,NR4A1,GRIN1,FOS,TIMP3,SERPINA1,SCG2,FGFR2,RND3,ITGA7,ITPR1,TCEAL4,CDK18,STK39,L1CAM,PKIA,SNPH,ARHGEF4 |
| 3.267e-05 | -10.33 | vacuolar lumen | cellular component | GO:0005775 | 87 | 22 | 17570 | 1756 |
LAMP2,GAA,HSPG2,GUSB,HEXB,SDC4,ASAH1,SDC1,ATP13A2,DAPK2,FUCA1,CTSL,GNS,SCARB2,HPSE,CTSV,GALNS,CTSA,GLA,LGMN,ARSB,GM2A |
| 3.269e-05 | -10.33 | GSE7852_TREG_VS_TCONV_FAT_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_UP | 194 | 38 | 17758 | 1761 |
LZTFL1,SORBS1,KIAA1462,NFKBIE,ATP8A1,ZCCHC24,IL18,TMEM170B,NCKAP1,PHLDA1,SYTL2,M6PR,NPNT,PRICKLE3,OSBPL3,ZFP36,MITF,FXYD5,TSPAN13,NEB,GM2A,ENPP4,TGIF1,ADCK3,DUSP4,SESN1,ALCAM,GPLD1,CMTM7,MAPKAPK2,MID1IP1,SWAP70,ARRB1,NFKBIZ,SERPINB6,ITGAV,PIEZO1,GEM |
| 3.269e-05 | -10.33 | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | 194 | 38 | 17758 | 1761 |
LAMP1,ARHGEF3,CDK17,SSH1,NLRX1,ZCCHC24,ACTR8,DCAF7,BARD1,IL18R1,TIPRL,ZFYVE16,ZNF432,FRYL,PHTF1,PLCG2,FAM13B,HLA-C,NCAM1,PTPRE,NCOA2,ARAP2,TACC1,ITCH,FURIN,ATP1B1,YES1,LDB2,PCTP,ATP10D,GALNT3,FAM64A,UEVLD,WIPI1,RAB11FIP1,ZNF701,RNF146,JARID2 |
| 3.269e-05 | -10.33 | GSE7852_TREG_VS_TCONV_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_UP | 194 | 38 | 17758 | 1761 |
NCKAP5,CCDC109B,UBASH3B,RALBP1,SDC4,NKRF,TGFBR1,PHLPP1,NUCB2,REPS1,ITGB8,MDFIC,TSPAN13,LMAN1,TIAM1,NEB,MGAT5,FAH,ABCC1,SOCS5,CPD,ELK3,TNIP1,SH3BGRL,CORO2A,KIF13A,DUSP4,PRKRA,PCTP,CD83,ENDOD1,MAPKAPK2,SWAP70,ANKRD6,MATN2,SP6,SH3BGRL2,NDFIP1 |
| 3.269e-05 | -10.33 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | 173 | 35 | 17758 | 1761 |
AVPI1,PDIA5,CYB561,GSTP1,IL17RB,SETDB2,PAPSS1,CST3,SGK1,VAT1,TECR,TSPAN1,CCDC88A,WBP5,C9orf9,RAPGEF2,SLC39A8,SYNE2,ZKSCAN2,MYEOV,PRKRA,PCTP,RANBP9,TP53I3,GABARAPL1,PRDX4,CXXC4,IDE,UAP1,COL13A1,ABHD12,P4HA2,FAM114A1,LRIG1,SPCS3 |
| 3.286e-05 | -10.32 | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | 187 | 37 | 17758 | 1761 |
DDX58,PARP12,CDKN1C,IL15,PSME2,TAP1,HERC5,IL27RA,FBXO6,HERC6,SLC25A43,SAC3D1,GNS,DTX3L,TNS3,PIK3AP1,METTL7A,IFIT1,OAS3,LAMP3,PARP9,MX1,B3GALT6,PLSCR1,IFITM3,USP18,BLVRA,IFIT3,ATP10D,SCARB2,TRIM69,C19orf66,SECTM1,IRF7,CMPK2,IFIH1,IFI6 |
| 3.286e-05 | -10.32 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | 187 | 37 | 17758 | 1761 |
ANXA3,TNRC6C,KIAA1462,UPF3B,ADD1,SCOC,SERPINE2,EPAS1,GALNT12,ARMC7,TMX4,PBX3,TRMT2B,PHLDA1,BMP2K,HLA-A,FZD6,PLS3,SESN3,ELMO2,SLC16A6,IMPAD1,TRIM21,TNFRSF12A,TECR,MYLIP,RBMS2,CORO2A,SCARB2,DNAJC10,UAP1,AGPAT2,H1F0,PEX2,HS3ST3B1,ARSB,TMEM14A |
| 3.286e-05 | -10.32 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | 187 | 37 | 17758 | 1761 |
GRN,SLC35D2,GGA1,CD82,NANS,M6PR,TNS3,TYMP,CTSC,KCNN4,LMO4,BHLHE41,FUT8,PAPSS1,FAM102A,CD70,MDFIC,CKAP4,PPIF,SEC61B,ING1,S100A4,HTATIP2,SOCS3,OPTN,HLA-B,ATP1A1,SLC25A4,WIPI1,CAB39,CTSA,ZMIZ1,TMEM14A,IFI6,NRBP1,EGLN1,EHD1 |
| 3.294e-05 | -10.32 | WILCOX_RESPONSE_TO_PROGESTERONE_UP | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_UP | 139 | 30 | 17758 | 1761 |
HMMR,PLA2G4A,FADS2,SHMT1,ARHGEF3,DLGAP5,HJURP,KIF20A,ASPM,PBK,CDC20,NDC80,NUSAP1,HMGN3,SAMD9,CCNB1,IDH1,CENPN,CDK1,FANCI,DNAJB9,TOP2A,CDKN2C,MDM1,METTL7A,SGK1,KLF5,CCNB2,ABCG1,TLL2 |
| 3.294e-05 | -10.32 | BMI1_DN_MEL18_DN.V1_UP | MSigDB lists | BMI1_DN_MEL18_DN.V1_UP | 139 | 30 | 17758 | 1761 |
ANXA3,RUSC2,PLAUR,PLEKHO1,ARL4C,COL7A1,LHFPL2,TNFSF9,CRISPLD2,NRP2,HTR1D,ATP13A2,CCND1,WEE1,TIMP3,ITGA3,ITGB8,COL13A1,FAM189A1,KCNN4,CSF1,FJX1,TMEM51,DUSP10,PIEZO1,PIM1,COL16A1,ABCA1,KLF7,EHD1 |
| 3.325e-05 | -10.31 | Glycosphingolipid biosynthesis - globo series | KEGG pathways | hsa00603 | 14 | 8 | 6908 | 758 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 3.325e-05 | -10.31 | Glycosphingolipid biosynthesis - globo series | KEGG pathways | ko00603 | 14 | 8 | 6908 | 758 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 3.332e-05 | -10.31 | LE_NEURONAL_DIFFERENTIATION_DN | MSigDB lists | LE_NEURONAL_DIFFERENTIATION_DN | 19 | 9 | 17758 | 1761 |
E2F7,CDC20,LHX6,KIF23,EIF4EBP2,PKMYT1,CCNB2,UBE2C,CKS2 |
| 3.378e-05 | -10.30 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 15590 | 1592 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,CXorf57,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,HAL,CDCA8,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,DNAH3,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,CYP1B1,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.378e-05 | -10.30 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 15590 | 1592 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,CXorf57,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,HAL,CDCA8,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,HAPLN3,CENPI,EPS8,EFHD2,HERC5,PBX3,DNAH3,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,CYP1B1,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,BROX,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.398e-05 | -10.29 | GRUETZMANN_PANCREATIC_CANCER_UP | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_UP | 350 | 59 | 17758 | 1761 |
GRN,MYL9,LTBP1,PCOLCE,GOLIM4,S100A11,TRIP10,GNPDA1,IQGAP1,RALBP1,EPS8,TAP1,DHX8,SLC1A3,CRABP2,SDC1,EMP2,TOP2A,RCN1,APLP2,SCNN1A,ITGA3,CTSC,CALD1,LMO4,PLCG2,CD9,SORL1,LGMN,GM2A,GPX4,CKS2,LAMP2,SEC23A,RHOA,CD55,MMD,PTPN9,PLAUR,PARP4,LOXL2,ITPR3,MYL12A,CASP4,DPYSL3,TIMP3,SERPINA1,KCNK1,PLOD2,SPINT2,KLF5,ATP1B3,GEM,RAP1GAP,UBE2C,AFAP1,MELK,ACOT7,ABCG1 |
| 3.418e-05 | -10.28 | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 126 | 28 | 17758 | 1761 |
MAP3K3,SORT1,RHOA,NFKBIE,AKT1,RIPK2,RPS6KA1,CALM1,PIK3R1,TP53,CALM3,ARHGDIB,MAPKAPK2,IRS2,CALM2,PLCG1,RPS6KA2,SHC3,NGFRAP1,NFKBIA,PLCG2,BAX,PIK3CA,MAPK11,PIK3CD,MAP3K5,GAB1,MAPK12 |
| 3.428e-05 | -10.28 | DELYS_THYROID_CANCER_DN | MSigDB lists | DELYS_THYROID_CANCER_DN | 223 | 42 | 17758 | 1761 |
WASF3,COL9A3,ALDH6A1,TSC22D3,NUCB2,NUP62CL,FBLN1,TSPAN7,SNTA1,MDM1,ADD3,CYR61,FOSB,AOX1,ALDH7A1,EPB41L4B,NCAM1,CITED2,NEB,CTH,FBLN5,ALDH2,HSPA12A,PRKCQ,LDB2,FOS,ENPP1,PLCH1,HLF,SLC4A4,FAAH,FGFR2,WFS1,MATN2,ITPR1,CLMN,TLE1,FHL1,TBC1D4,LIFR,TOB1,CYBRD1 |
| 3.435e-05 | -10.28 | regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014066 | 74 | 20 | 16441 | 1675 |
NKX3-1,SERPINE2,SOX9,ERBB2,PDGFB,C3orf58,PDGFA,SEMA4D,PTEN,PIK3AP1,DAB2IP,TWIST1,NRG1,MYDGF,ERBB3,GPER1,UNC5B,F2RL1,F2R,RASGRP1 |
| 3.557e-05 | -10.24 | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | 76 | 20 | 17758 | 1761 |
NFKBIE,PLSCR1,TNIP1,RIPK2,SLC11A2,CD40,CASP4,FAS,IER3,SLCO4A1,CXCL16,CSF1,PLK2,NFKBIA,NFKBIZ,RAB20,RFX5,ICOSLG,PTPRE,MAFF |
| 3.564e-05 | -10.24 | STEIN_ESRRA_TARGETS_UP | MSigDB lists | STEIN_ESRRA_TARGETS_UP | 366 | 61 | 17758 | 1761 |
GAS2L1,ACACB,TRIM2,CEP70,UGP2,EPAS1,RPS6KA1,TMX4,NDRG2,PRSS22,GDF15,TEX2,NANS,ISOC2,MGST2,SCML1,CYP1A1,CTSC,METTL7A,KCNN4,MITF,OPN3,FAM63A,ECI2,TRPC1,GOT1,MANF,EGLN3,SULT2B1,ALDH3A2,GM2A,TRAK2,PPIF,OPLAH,PGM1,CASP9,HTATIP2,ARFRP1,ATP1B1,SPTLC2,PCTP,GABARAPL1,EPN3,NUCB1,SLC25A4,ETS2,TJP3,ACADSB,WIPI1,TIMM8A,SLC2A6,OTUB2,AURKA,ZNF165,MDH1,PLIN3,RAP1GAP,HOOK1,PPP2R2D,LIFR,EGLN1 |
| 3.582e-05 | -10.24 | neoplasm | COSMIC cancer mutations | neoplasm | 15558 | 1589 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,DPP8,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CLDN4,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,RIMS3,ATP5H,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,ULBP2,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,RNF224,TPRN,NQO1,PTTG1,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,PIK3CA,IRF2,SNX16,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ADAM15,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,LCA5,FMN1,FAM160A1,BCL9,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,LPIN3,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,HNRNPH2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 3.679e-05 | -10.21 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 195 | 38 | 17758 | 1761 |
HECA,ARHGEF3,ARMCX3,CDKN1C,ZCCHC24,PYROXD2,CD82,HABP4,FAM198B,VASH1,SLC25A36,ADD3,TRANK1,SNX18,METTL7A,DPYSL2,MEGF8,IL6ST,CST3,BCL6,ANKRD12,CRTAP,FADS2,TIMP2,MBP,PTPRU,H2AFV,SESN1,POR,GABARAPL1,CNTNAP1,NCOA3,RAB11FIP2,C19orf66,CSF1,SLC27A1,CYBRD1,RNF146 |
| 3.679e-05 | -10.21 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | 195 | 38 | 17758 | 1761 |
CCNE2,TXN,HJURP,NQO1,VANGL1,ABCG2,CDCA8,KIF23,CCNB1,SAC3D1,TOP2A,TYMP,TUBG1,LGMN,FAH,LAMP3,GCNT1,CKS2,HMMR,ALDH2,CENPA,SHMT1,KIF20A,ASPM,CDC20,NUSAP1,RAB38,SLC25A5,KIF11,ADRBK2,PRDX4,SLCO4A1,CENPE,NCAPG2,CCNB2,UBE2C,ESPL1,ACOT7 |
| 3.679e-05 | -10.21 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 195 | 38 | 17758 | 1761 |
SEMA6B,HECA,AVPI1,PAPSS2,SSH1,EPAS1,NUAK1,XYLT1,CTDSPL,ARL4C,OAT,STIL,NCS1,LMNA,SGPL1,SLC16A6,PAQR5,PPP4R1,COL6A1,OPN3,CD9,NOTCH3,PDE4D,TIPARP,RIMS2,PDGFC,PGM1,MMD,CASP9,SOCS3,GABARAPL1,WIPI1,PLK2,NR4A3,ALPK3,LTBP2,ZMIZ1,JARID2 |
| 3.703e-05 | -10.20 | cell adhesion | biological process | GO:0007155 | 1036 | 145 | 16441 | 1675 |
MYL9,BCAM,KIAA1462,EPHA4,RET,F11R,EPDR1,EPCAM,MUC4,CTGF,NPNT,ELMO2,DLG1,CLDN4,PIK3CD,TINAGL1,CTTN,TLN2,TIAM1,SMAGP,CYP1B1,SGCE,CELSR2,TNIP1,EZR,LOXL2,COL12A1,HPSE,ARF6,HSPB1,F2RL1,CD99,RUNX2,BVES,THEMIS2,NUAK1,ITGA6,HLA-E,SOX9,CNTNAP2,MERTK,IL18R1,ITGA3,CYR61,LYPD3,FLRT3,KIF13B,COL6A1,TNFRSF12A,NCAM1,WNT3A,EPB41L5,PODXL2,PCDH1,RGMB,MICB,SCRIB,VEZT,EPHA1,ANTXR1,CDK5R1,FAS,GNAS,PTPRF,SCARB2,PVRL2,SEMA4D,COL13A1,PLPP3,ITGA7,CGREF1,PCDH19,EGFL7,COL16A1,SORBS1,GRHL2,IL15,TP53,TESK2,PKP2,COL18A1,EMP2,DDR1,NOV,MUC16,CDH1,KIF14,CDH3,EPHB4,CAMSAP3,COL6A2,RIPK2,FZD4,PTPRU,PTGER4,ERBB2IP,ATP1B1,ALCAM,DAG1,MYL12A,FZD7,DDOST,AXL,PTK7,ANXA9,FBLIM1,CDH22,HAPLN3,ADGRG1,CD63,GNE,SELL,BTN3A1,EFNB1,SRPX2,LGALS3BP,NRP2,SIRPA,NEO1,IGSF9,ITGB8,BMP7,BAX,CD9,ADAM15,ARVCF,SYK,GCNT1,FARP2,PVRL4,HES1,RHOA,FBLN5,RC3H2,COL7A1,FNDC3A,BCAR1,CNTNAP1,FAT4,RND3,ITGAV,FZD5,ICOSLG,L1CAM,CD33 |
| 3.707e-05 | -10.20 | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 188 | 37 | 17758 | 1761 |
LAMP1,AVPI1,EPAS1,HEXB,NENF,NTAN1,SPR,BCAP31,LMNA,TNS3,CA2,EFR3A,MITF,PAPSS1,COL6A1,TUBG1,VAT1,GOT1,TECR,ALDH3A2,GM2A,FAM69A,FAH,TIMP2,MMD,ACO1,ICMT,CYB5A,PRDX4,ATP1A1,CORO1C,SETD3,DBI,MDH1,PLOD3,ARSB,HSPB1 |
| 3.707e-05 | -10.20 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 188 | 37 | 17758 | 1761 |
LGALS3,CD63,CD82,IQGAP1,CAST,PTTG1,EPHA4,NDC80,EFHD2,WEE1,CTSC,RGS3,OSBPL3,PAPSS1,DUSP10,TAGLN2,FAR2,MYBL1,MYO5A,ABCC1,RAPGEF2,S100A4,PARP4,EZR,EIF2AK1,RNF19B,ARHGAP35,FAS,SLC6A6,RAB11FIP1,NOD2,AGFG2,EIF4EBP2,CTSA,PIEZO1,MAP3K5,AHR |
| 3.707e-05 | -10.20 | GSE17721_CTRL_VS_LPS_1H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_1H_BMDM_DN | 188 | 37 | 17758 | 1761 |
MRC2,FLYWCH2,FAM81A,CYP26A1,DNAJB9,IER3,BTG3,CYR61,LLGL2,ZFP36,BHLHE41,TPST1,CITED2,TIPARP,C9orf72,FBLN5,B3GNT2,RIPK2,PLSCR1,NR4A1,SH3BGRL,PTGER4,CR2,KIF13A,ASB13,FOS,COL12A1,EDNRA,PGF,IRS2,FAM64A,RND3,NKD1,OSR1,MAFF,PROM2,EHD1 |
| 3.712e-05 | -10.20 | cell projection membrane | cellular component | GO:0031253 | 288 | 51 | 17570 | 1756 |
DDX58,TTC8,PACSIN2,TCTN2,NF2,BVES,EPS8,GABRG2,CNTNAP2,NCKAP1,DHRS3,APC2,EPS8L2,SCNN1A,ADORA1,ITGA3,DLG1,ATP8B1,RP2,PACSIN1,SPRY2,GPR161,EPB41L5,SGCE,RHOA,PLAUR,SYNE2,CYS1,GRIN1,UTRN,SPATA13,EZR,SLC11A2,AIF1L,BBS2,ANTXR1,ARF4,GABARAPL1,RASGRP2,PTPRJ,PHLPP2,SPTBN5,NRG1,GPER1,PIEZO1,ITGAV,ARF6,CYBRD1,EHD1,PROM2,ARHGEF4 |
| 3.718e-05 | -10.20 | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | 181 | 36 | 17758 | 1761 |
BIN1,SIGIRR,HECA,HAPLN3,GALNT12,CD82,EPHA4,AES,ISYNA1,ANO9,PSIP1,TMEM63A,WWP1,TECR,RCAN3,MAST4,RASGRP1,SUSD3,FBXL16,STMN3,PRKCQ,ITPR3,KCTD2,PRIM1,OPTN,PLCG1,KLF12,LRIG1,AMMECR1,INPP4B,FAM117A,ST3GAL1,TMEM14A,TRAF5,CBX7,DOCK9 |
| 3.718e-05 | -10.20 | regulation of cell cycle | biological process | GO:0051726 | 952 | 135 | 16441 | 1675 |
CCNI,HECA,CASP3,CUL4B,PSME1,CCNB1,VASH1,PDGFB,BARD1,FANCI,CALM2,SUSD2,CDKN2C,WEE1,BTG3,CYP1A1,PSMD1,RPS6KA2,CTGF,DLG1,PLK1,CCNF,ANLN,SESN1,CDK1,RHEB,PLK2,MADD,CAB39,HDAC1,E2F8,RRAGD,PRKAA2,CDK17,CDKN1C,SOX9,CALM3,KIF23,MECOM,TFAP4,IGF1R,NEK2,PIM1,CALM1,MYBL2,STRADB,SCRIB,NUBP1,PSMA4,CDK5R1,NUDT16,PRKAG2,TJP3,CGREF1,CDCA5,FAM83D,AURKA,STK39,CDK18,CCNB2,GAS2L1,CCNE2,DLGAP5,FOXM1,PSME2,CAST,PTTG1,CTDSPL,TP53,BCL2L1,PRKACA,STIL,IER3,CCND1,DACT1,KIF14,PLK4,CDKN1B,DAB2IP,CDKN2D,CTDSP2,CKS2,SIRT1,TIMP2,AKT1,FIGNL1,CDC20,NUSAP1,PRKCQ,PKMYT1,RAD17,MAP3K6,JADE1,STK26,RBL1,CDK19,OVOL1,MAPK12,BIN1,NKX3-1,CIT,HERC5,PSMD10,TGFBR1,ETS1,BEX2,DIRAS3,TOP2A,E2F7,CDK16,PTEN,BMP7,BAX,TRIM21,BUB1,CITED2,HES1,RHOA,ZWINT,PSMB4,NR4A1,ASPM,RGCC,RUNX3,KIF11,BORA,CDK5RAP1,FGFR2,NR4A3,FHL1,CENPE,GPER1,UBE2C,ESPL1,PKIA |
| 3.751e-05 | -10.19 | endosomal part | cellular component | GO:0044440 | 426 | 69 | 17570 | 1756 |
LAMP1,EPHA4,RET,ERBB2,MVB12B,ZFYVE9,SLC9A7,ZFYVE16,RAB15,ATP6V0B,ACAP2,WDR44,STEAP2,ABCA2,SNX16,ECE1,MARCH2,RAB27B,SNX10,TMEM9,LAMP2,CLCN3,KIF13A,SLC11A2,RAB38,WIPI1,SLC9A6,IRF7,ARF6,STARD3NL,RRAGD,GOLIM4,PACSIN2,SORT1,GGA1,CD63,HLA-F,HLA-E,ATP9A,TMEM55B,RAB23,FAM21C,VPS26A,PARM1,HLA-A,MARCH8,ZNRF2,SNX18,KIAA0319,PLEKHF1,HLA-C,WNT3A,PIKFYVE,TPCN1,SUN2,MMD,IFITM3,ANTXR1,STEAP1,CPTP,CTSL,HLA-B,RAB11FIP2,RAP2C,PLD1,PLIN3,FZD5,NDFIP1,EHD1 |
| 3.791e-05 | -10.18 | catalytic activity | molecular function | GO:0003824 | 5611 | 643 | 16491 | 1673 |
ACACB,KLK10,AK7,AASS,RET,HEXB,FBXO2,DHX8,LACTB2,ISOC2,DPP8,CA8,BARD1,DAPK2,WEE1,PSMD1,UBE2T,CYP2S1,ALDH1A3,FUT1,TUBG1,CRY2,TINAGL1,PIK3CD,ACOX2,TIPARP,APOBEC3G,MGAT5,ERAP2,SMARCA2,FBXL16,TNIP1,CDA,LOXL2,F12,ICMT,RNF19B,CYP4F3,ARF4,PIAS3,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,HDAC1,ITPKA,ARF6,ALDH6A1,NUAK1,SOX9,RAB23,COX6C,MERTK,RABGGTA,ATG4A,GNS,MARCH8,ATP5H,NEK2,PCYOX1,MAP3K9,ALPK1,DGKG,MYLIP,NDUFA12,MCCC2,KIF20A,ERO1A,SPTLC2,PSMA4,GNA11,CYB5A,DCP2,DHX32,STK17A,PTPRF,NCOA3,SETD3,AURKA,MDH1,STK39,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,NQO1,GALNT12,INPP5D,TESK2,PRSS22,GRK6,MGST2,PRKACA,APPBP2,CDS1,CCND1,RNF220,XYLT2,ENPP5,ACSL4,ARL4D,DLG3,RAB27B,MX1,ENPP4,SSH3,APOBEC3D,RIPK2,PTPN9,SAT1,HTATIP2,RAB38,XRCC6BP1,ALDH3B1,CDK19,AXL,INPP4B,PNPLA6,TRABD2A,ISOC1,MAPK12,OSGIN2,PDIA3,CTSZ,PKN1,PLPPR4,GSTP1,PDIA4,SGPL1,DTX3L,DIRAS3,FUT2,SLC27A6,CTSC,ARSG,ALG13,MGAT4A,FAM20B,KLC3,ECI2,ADAM15,WWP1,MAPK11,PARP9,OPLAH,ADAMTS2,ELOVL3,UBE2A,AK4,BLVRA,NEURL1B,GALNT3,PLOD2,ACVRL1,PPM1H,HMGA1,CENPE,CMPK2,ACOT7,CYBRD1,TLL2,UNKL,TRIM2,GNPDA1,PPM1J,CNOT8,CUL4B,EPHA4,MGAT5B,HDAC6,RPS6KA2,MKRN3,PAPSS1,PAPL,PASK,ABCA2,DUSP10,DDX59,PLK1,ARFRP1,KLK6,IDH1,CDK1,RHEB,DPYSL3,KDM4D,TRIM9,PLCH1,HS6ST1,AGPAT2,P4HA2,DOLPP1,PIK3C2B,RRAGD,PRSS8,PRKAA2,LMTK3,PARP12,UBASH3B,ASAH1,ADCK5,RAB6A,B4GALT4,DHRS3,B4GALNT1,UBE2Q2,IGF1R,KIF13B,AHCY,PIM1,FAR2,PLCB2,ALDH3A2,ABCC1,CYP26B1,DPYSL5,CHSY3,TESK1,MGAT4B,STRADB,EIF2AK1,PDK3,G2E3,CDK5R1,MAPKAPK2,PHLPP2,KBTBD2,PRPS2,P4HA3,ZDHHC7,PLD1,ATP1B3,RNF146,USP43,UGP2,P3H2,TMX4,XYLT1,CTDSPL,ERBB2,LPIN3,KBTBD11,CYP26A1,ATP6V0B,PLCG2,SRR,PLK4,ZDHHC23,VAT1,GLB1L2,OAS3,EGLN3,MINPP1,CTDSP2,GM2A,CTH,SULF2,PPIF,CPD,SIRT1,AKT1,FIGNL1,ACO1,ATP13A2,DUOX1,DNAJC10,TAPBP,ATP1A1,IDE,PTPRJ,ABHD12,PTK7,STK38,MMP17,ADAMTS14,C1orf43,LTA4H,ST3GAL1,AIFM3,NDST3,MAN2B2,CMAS,PINK1,KLHL13,HAL,BLVRB,GNE,ERI2,DSE,LBR,NRP2,ZDHHC21,CDK16,ALPP,GTF2F2,UBE2J1,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,SYK,ATP2B1,GCNT1,FAH,RHOA,PSMB4,GUSB,AMFR,GGH,PELI3,RNPEP,TXNDC11,DGKE,SCRN2,PRDX4,FUCA1,NAT1,SPCS3,UBE2C,PTGES,HIPK3,DIS3L,CFAP61,GAA,TXN,SSH1,ATP8A1,TAP1,NANS,CAMK1D,PJA2,OAT,CCNB1,TYMP,CYP1A1,PALD1,PIK3CA,AOX1,STEAP2,MARCH2,SMYD5,METAP2,LOC81691,TMEM68,KIFC2,ACVR1C,PBK,CASP9,KIF13A,GALNT7,PIF1,TP53I3,POR,PRIM1,GDE1,PTER,GNPTAB,PLK2,PRDM5,BMP1,DHTKD1,WBSCR27,TRAF5,DDX58,CDK17,MRPL44,TMEM55B,DGKQ,KIF23,NDUFA4,ISYNA1,HERC6,BMP2K,KIAA1161,ZNRF2,BDH1,PPP4R1,ADCK2,PRKG1,DAPK1,TPST1,PIKFYVE,MAST4,GFPT1,FADS2,PRODH,PMPCB,B3GNT7,DDB2,KLK5,PRSS23,MMD,ADCK3,LPGAT1,PIP4K2C,EPHA1,ATP8B3,GLT8D2,DGKH,MMP15,PRKAG2,FAAH,DCK,PELI2,CSNK1G1,AGBL5,KLK7,CDK18,MAP3K5,IFIH1,NRBP1,PLA2G4A,DLGAP5,ST14,RALBP1,RPS6KA1,ATP2C2,RNF182,FTH1,AIFM2,DDR1,TMPRSS4,CYP39A1,ZFYVE9,APOBEC3B,EPHB4,PDE4D,PHKA2,LGMN,SULT2B1,NAGA,ATG4D,GPX4,MYO5B,CAPN6,CYB5R2,PANK1,KIF1C,PRKCQ,PKMYT1,RAD17,ATP1B1,ATP10D,PRDM11,EPHA10,AMZ2,JAK1,DDOST,STK26,SLC27A1,HS3ST3B1,MLKL,SLC27A3,NUDT6,ATP9A,ARL4C,HERC5,APOBEC3H,CYB561,FBXO6,DNAH3,SPR,WWP2,GNB5,RNF128,PTEN,FUT8,SGK3,ATP8B1,ERBB3,CNOT6L,TRIM62,NCOA2,OSGIN1,ALDH2,SHMT1,B3GNT2,LONRF3,MPP1,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,KIF11,ARSK,GPLD1,CDK5RAP1,ACADSB,FGFR2,ABCB1,RYK,PGM2L1,ERAP1,LRRK1,ARSB,ESPL1,OCLN,MELK,JARID2,NMRK1,CASP3,LTBP1,UGT8,CRYM,CPT2,CAMKK1,VARS2,ERP29,TRIM68,TSEN34,CHPF,ABCD4,RAB15,METTL7A,DPYSL2,IMPAD1,DLG1,AKR1B1,RAB20,MYH14,TECR,PTPRE,CYP1B1,ATL1,TRIM8,USP18,ITCH,ARHGDIB,ROR1,MRPS36,ADRBK2,STK17B,TYSND1,EDNRA,MAN2A2,NEIL1,HPSE,UEVLD,GLA,RAP1GAP,CAPN1,CPPED1,PCSK5,FAM213B,PEX6,PYROXD2,ABCG2,TEC,PHLPP1,ADAMTSL4,B3GALNT1,OTUD1,CA2,ZRANB1,NCEH1,GAD1,DESI2,OXR1,GYLTL1B,PDE5A,PDIK1L,AMDHD1,STEAP1,GLCE,FECH,GNAS,NUDT16,UAP1,PLPP3,ALPK3,YOD1,CTSA,JAK3,LMO7,DYNLRB1,HDAC11,PDIA5,MRAS,SETDB2,CYP4F11,ZDHHC12,KIF14,GOT1,RPN2,ECE1,PDIA6,SCYL3,SEPHS1,MAP3K3,GCA,PTPRU,GLO1,DUSP4,CASP4,MAP3K6,ALDH5A1,PEX2,CYP2U1,ABCA1,GCLM,ENO2,CIT,TGFBR1,NOTUM,TRMT2B,POMGNT1,TRIB2,NTAN1,SBF1,HDAC9,TOP2A,KIF5B,ADRBK1,ADORA1,A4GALT,GALNS,MYO5A,B3GALT6,PGM1,RAB3B,CFAP46,GCLC,RC3H2,OGDHL,NADK2,KLHL2,CTSL,ENDOD1,RND3,TRIM69,PRCP,DHRS2,CTSV,DTX4,OTUB2,ARRB1,GEM,PLOD3,ABCG1 |
| 3.816e-05 | -10.17 | YAGI_AML_WITH_11Q23_REARRANGED | MSigDB lists | YAGI_AML_WITH_11Q23_REARRANGED | 336 | 57 | 17758 | 1761 |
FAM169A,PPP1R2,HSPG2,CAST,SLC25A13,CTDSPL,RET,PBX3,ITPR2,VASH1,KBTBD11,ERP29,EMP2,FZD6,HDAC9,DOPEY2,CTGF,TAF1B,SHC3,BMP7,ATP5H,PLCG2,RRBP1,AKR1B1,ADAM15,OSTF1,PIK3CD,PIM1,NR2C1,ALDH3A2,SLC16A5,CPD,ENPP4,COL6A2,ELK3,NR3C1,TACC1,GCLC,MICB,PLAUR,AK4,PRKCQ,ATP1B1,YES1,ABR,NFIX,RASGRP2,TIMP3,SEMA4D,ITGA7,WFS1,MMP17,LRIG1,EIF4EBP2,ITGAV,TMEM159,JAK3 |
| 3.829e-05 | -10.17 | FERM_domain | interpro domains | IPR000299 | 48 | 15 | 18293 | 1814 |
EPB41L5,FRMPD3,PLEKHH2,JAK1,NF2,FRMD4A,FRMD6,EZR,EPB41L4B,EPB41L4A,TLN2,JAK3,MYLIP,FRMD4B,FARP2 |
| 3.834e-05 | -10.17 | PROTEIN_KINASE_ACTIVITY | MSigDB lists | PROTEIN_KINASE_ACTIVITY | 283 | 50 | 17758 | 1761 |
PINK1,CIT,RPS6KA1,TESK2,ERBB2,TGFBR1,TRIB2,MERTK,DDR1,NRP2,DAPK2,RPS6KA2,IGF1R,SGK3,NEK2,MAP3K9,PLK4,SGK1,MAPK11,ERBB3,PIM1,PHKA2,MAP3K3,PLK1,RIPK2,AKT1,ACVR1C,TESK1,PBK,STRADB,EIF2AK1,PDK3,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,CDK5R1,STK17A,MAPKAPK2,ACVRL1,PTK7,LIMK1,AXL,STK38,RYK,NR4A3,MAP3K5,HIPK3,MAPK12 |
| 3.834e-05 | -10.17 | BROWNE_HCMV_INFECTION_14HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_DN | 283 | 50 | 17758 | 1761 |
KIAA1462,PAPSS2,ADD1,EPAS1,PEX6,ZCCHC24,CIT,RASA2,BLVRB,NDC80,RGS20,ERBB2,GPSM2,SPTB,SIRPA,LMNA,APPBP2,MECOM,WWP2,APOBEC3B,ADD3,ST5,ITGA3,TAF1B,N4BP3,AIM1,BAX,ABCA2,CLDN4,IRF2,PIK3CD,RAB27B,SGCB,FAH,ABCC1,CYP1B1,HMMR,PLAUR,PARP4,BTN3A2,DIAPH2,PDE5A,TP53I3,FAS,NR1D2,AXL,INPP4B,CENPE,ITPKA,CCNB2 |
| 3.870e-05 | -10.16 | Signaling by Interleukins | REACTOME pathways | R-HSA-449147 | 311 | 56 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,INPP5D,PSMD10,ERBB2,NRG2,CALM3,IL18,PSME1,TEC,PDGFB,PRKACA,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,IL6ST,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,MAP3K3,RASGRF1,PSMB4,RIPK2,RAPGEF2,PIK3R1,CALM1,GRIN1,PELI3,YES1,DUSP4,PSMA4,RASA1,SOCS3,IRS2,JAK1,PPP2R5A,FGFR2,PELI2,NOD2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 3.934e-05 | -10.14 | large_intestine-colon-carcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma | 2718 | 327 | 17775 | 1757 |
SUN1,HECA,ACACB,KLK10,LGR4,IL15RA,SSH1,HSPG2,VANGL1,TMEM41B,ATP8A1,RET,CACNA2D2,PLXNA1,BARD1,FAM46C,NCS1,ZFP36,RGS3,OSBPL3,AOX1,PIK3CA,TACSTD2,SEMA3G,APOBEC3G,ERAP2,NWD1,SMARCA2,KIFC2,SPATA18,HSPA12A,TMEM151A,TFAP2C,CCNF,COL12A1,GNPTAB,LRIG1,TRAF3IP1,FAM110C,DHTKD1,SERPINB6,NFKBIZ,F2RL1,GAB1,LZTS1,FRMD4A,GGA1,TBC1D1,ITGA6,SOX9,DGKQ,SLC1A3,MERTK,TTYH3,LMNA,MESDC2,RAVER2,ELF3,TFAP4,DOPEY2,FRY,LYPD3,ZNRF2,SNX18,VASN,MAP3K9,SORL1,ALPK1,CACNA1D,PANX2,PIKFYVE,SYTL3,C9orf72,MCCC2,HPS3,SALL4,AMER1,SPTLC2,RASA1,PTPRF,PRKAG2,PELI2,FGD6,PCDH19,CABIN1,KLK7,ZNF502,XDH,EHD1,TPRN,PAPSS2,DLGAP5,ARMCX3,ST14,THRA,DDIT4L,RNF182,PRSS22,EPS8L2,APPBP2,ZNF75D,ST5,CDH1,CNNM4,DAB2IP,ACSL4,TSPAN1,MYO5B,SEC23A,COL6A2,SYNE2,PANK1,UTRN,TMEM144,PRKCQ,ATP1B1,C15orf39,XRCC6BP1,ALCAM,FZD7,GABARAPL1,NIN,IRS2,AXL,ZNF704,PLEKHG1,PNPLA6,SLC27A1,KLF5,MLKL,ATP9A,OSGIN2,HERC5,ANO9,GSTP1,DNAH3,NEO1,PDIA4,WWP2,FAM111A,TMEM87B,ITGB8,PHF7,ARSG,ATP8B1,MAPK11,ERBB3,SGCB,TRIM62,FARP2,PDGFC,ARAP2,GRIN1,FURIN,FOS,GALNT3,CNTNAP1,NUCB1,FGFR2,RAB11FIP2,TBX18,ABCB1,CENPE,ITGAV,FHL1,OSR1,WDR62,NCAPG2,CPEB2,ESPL1,ACOT7,DEF6,MELK,JARID2,EXPH5,BCAM,PPM1J,CPT2,LMCD1,ITPR2,PDGFB,DENND2D,PLS3,ARHGEF10L,SIPA1L2,BTG3,LRRC6,ZCCHC12,IL6ST,DPYSL2,ANKFN1,ABCA2,SUN3,SLC39A10,TLN2,TECR,CYP1B1,ZNF462,ATL1,MCTP1,CELSR2,CBX6,NFE2L1,ROR1,IDH1,PTGFRN,KDM4D,DZIP1L,MFAP3L,ZNF114,KLF12,MAP2,CPPED1,PCSK5,RRAGD,BMF,ZNF395,CHCHD7,UBASH3B,ABCG2,ADCK5,CNTNAP2,FBLN1,IGF1R,RINL,COL6A1,FXYD5,AHCY,LIMCH1,RFX5,ZRANB1,CCDC88A,MDFI,ABCC1,PCDH1,CORO2A,SCRIB,RNF113A,C3orf58,MFSD7,CDK5R1,GLCE,GNAS,BCAR3,ONECUT1,ITGA7,SLC2A6,NLRC5,SH3BP4,CTSA,AFAP1,RNF146,PROM2,LMO7,FOXM1,XYLT1,TP53,IL27RA,LPIN3,STIL,ZNF687,CYP4F11,KIF14,FRYL,N4BP3,LHX6,PLCG2,NOTCH3,SEPHS1,CTH,MBP,OSTM1,ACO1,DAG1,PTPRJ,RBL1,ADAMTS14,LTA4H,ABCA1,PPP2R2D,GOLIM4,ARHGEF11,RUSC2,FRMD6,LRP4,FAM167A,AIP,PPP2R3A,TMEM63A,ZDHHC21,M6PR,KIF5B,LLGL2,A4GALT,ABCD1,BUB1,KLF9,CLIP2,SYK,MYO5A,FAH,DLGAP1,SYPL1,ASPM,PLAUR,NR4A1,RC3H2,COL7A1,RUNX3,GGH,PELI3,FNDC3A,RNPEP,LEPR,SCRN2,FUCA1,FAT4,SERPINA1,C2orf70,TRIM69,UACA,GRAMD1C,TBC1D4,AHR,L1CAM,ARHGEF4,GOLGB1 |
| 3.949e-05 | -10.14 | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 422 | 68 | 17758 | 1761 |
UGP2,PAPSS2,RPS6KA1,ERBB2,TESK2,DDR1,CDS1,DAPK2,RPS6KA2,PAPSS1,DLG1,PIK3CA,PLK4,PHKA2,MAP3K3,PLK1,RIPK2,AKT1,ACVR1C,PBK,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,PRIM1,PTK7,LIMK1,AXL,STK38,ITPKA,MAPK12,PINK1,CIT,GNE,DGKQ,TGFBR1,TRIB2,MERTK,NRP2,IGF1R,ARSG,MAP3K9,NEK2,SGK3,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,DGKG,TESK1,MPP1,STRADB,EIF2AK1,PDK3,DGKE,CDK5R1,STK17A,MAPKAPK2,UAP1,ACVRL1,DCK,PRPS2,RYK,NR4A3,MAP3K5,HIPK3 |
| 3.957e-05 | -10.14 | Interleukin-3, 5 and GM-CSF signaling | REACTOME pathways | R-HSA-512988 | 254 | 48 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,INPP5D,PSMD10,ERBB2,NRG2,CALM3,PSME1,TEC,PDGFB,PRKACA,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,YES1,DUSP4,PSMA4,RASA1,IRS2,JAK1,PPP2R5A,FGFR2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 3.962e-05 | -10.14 | positive regulation of locomotion | biological process | GO:0040017 | 396 | 66 | 16441 | 1675 |
ATP8A1,RET,COL18A1,CD274,CAMK1D,HDAC6,PDGFB,PDGFA,EPCAM,DAPK2,ARTN,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,DOCK4,AKT1,SYNE2,DOCK5,IRS2,PLCG1,FAM110C,F2RL1,HSPB1,ANXA3,SEMA6B,LGALS3,BVES,SOX9,SELL,FBLN1,ETS1,SRPX2,NRP2,HDAC9,CXCL16,ITGA3,IGF1R,CYR61,MEGF8,TRIM21,EPB41L5,SUN2,RHOA,RAPGEF2,ANO6,PIK3R1,FURIN,EPHA1,BCAR1,STX3,GPLD1,ONECUT1,SWAP70,SCG2,SEMA4D,CSF1,PLPP3,GPER1,ITGAV,CFAP20,SEMA3A |
| 3.976e-05 | -10.13 | ODONNELL_TFRC_TARGETS_DN | MSigDB lists | ODONNELL_TFRC_TARGETS_DN | 127 | 28 | 17758 | 1761 |
HMMR,ARHGAP11A,PLK1,PCGF5,CENPA,SPC25,KIF20A,DEPDC1,DLGAP5,FOXM1,ASPM,CDC20,NDC80,MYBL2,CCNB1,ANLN,KIF11,CDK1,DCP2,TOP2A,NPNT,KIF14,RANBP1,PLK4,FAM83D,AURKA,BUB1,CENPE |
| 3.993e-05 | -10.13 | tube morphogenesis | biological process | GO:0035239 | 343 | 59 | 16441 | 1675 |
CTHRC1,NKX3-1,GRHL2,LGR4,ST14,EPHA4,SOX9,SDC4,RET,RAB23,CTSZ,NCKAP1,PRKACA,STIL,FZD6,CTNNBIP1,SETDB2,NPNT,DACT1,BMP7,LMO4,MEGF8,DLG1,BAX,TWIST1,DAB2IP,TACSTD2,WNT3A,SLC12A2,ETV4,SPRY2,DVL2,EPB41L5,HES1,TGIF1,FMN1,SALL4,TFAP2C,PRICKLE1,SCRIB,NPHP3,DAG1,NFIB,EDNRA,ARHGAP35,NCOA3,FAT4,ACVRL1,SHROOM3,FGFR2,PTK7,CSF1,SPINT2,NR4A3,SOX8,OSR1,RARG,COBL,ADAMTS16 |
| 4.003e-05 | -10.13 | regulation of response to stress | biological process | GO:0080134 | 1397 | 187 | 16441 | 1675 |
LAMP1,TXN,DNAJC3,EPHA4,ARFGEF1,LMCD1,TAP1,PSME1,IL18,ITPR2,VASH1,HDAC6,PDGFB,ERP29,CALM2,SESN3,PSMD1,AP1M2,RPS6KA2,CTGF,IL6ST,TSPAN6,DLG1,DUSP10,CTTN,SCARA3,APOBEC3G,SMAGP,RASGRP1,CD55,TNIP1,ITCH,PBK,USP18,CASP9,SLC35C1,EZR,F12,SESN1,ABR,KDM4D,GPRC5B,HPSE,DNM1L,ANKRD6,TRAF3IP1,NOD2,HSPB1,F2RL1,GAB1,LZTS1,DDX58,PRKAA2,SERPINE2,SCOC,NUAK1,HLA-E,UBASH3B,CALM3,TEC,SLC1A3,PHLPP1,MECOM,IGF1R,PIK3AP1,FAM13B,MAP3K9,PRKG1,MDFIC,TNFRSF12A,ALPK1,PIKFYVE,NUP85,MDFI,KLK5,MICB,CALM1,ANO6,PIP4K2C,EIF2AK1,ELK1,PSMA4,FECH,MAPKAPK2,PTPRF,NUDT16,PVRL2,PELI2,PLPP3,ITPR1,NFKBIA,NLRC5,MDH1,STK39,YOD1,KLK7,MAP3K5,IFIH1,NUP58,TMEM173,XDH,SPRED1,NLRX1,IL15,FOXM1,RPS6KA1,PSME2,TP53,SLC7A2,BCL2L1,PRKACA,BCAP31,IER3,PDGFA,NOV,FAM46A,DACT1,PLCG2,BCL6,DAB2IP,TWIST1,IFIT1,LGMN,CDKN2D,F2R,DVL2,MAP3K3,SIRT1,ENPP4,ERLEC1,RIPK2,AKT1,FIGNL1,FZD4,PTGER4,PRKCQ,ATP1B1,ITPR3,DUSP4,MAP3K6,CASP4,FZD7,SOCS3,JAK1,CDK19,STK26,WFS1,IRF7,PINK1,NKX3-1,HERC5,PSMD10,PKN1,ETS1,GSTP1,FGF19,HLA-A,CD109,ADORA1,PTEN,BMP7,UBE2J1,BAX,TMBIM6,MAPK11,CNPY3,SYK,PARP9,FBLN5,PLSCR1,PSMB4,PLAUR,PIK3R1,PPARA,FOS,MAPK8IP1,CTSL,HLA-B,NR1D2,NMI,NR4A3,ERAP1,GPER1,HMGA1,FZD5,NDFIP1,HIPK3 |
| 4.005e-05 | -10.13 | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 239 | 44 | 17758 | 1761 |
SLC25A24,RUNX2,ARMCX3,TTC39B,ARL4C,HMGN3,IL13RA1,SEPP1,DHRS3,FAM46C,IL18R1,EPCAM,B3GALNT1,TNS3,IGF1R,RNF128,ARSG,OSBPL3,CD9,MDFIC,CTTN,TIAM1,F2R,PTPRE,SLC16A5,FARP2,GCA,PLSCR1,IFITM3,STAT4,OXR1,GGH,PRKCQ,ALCAM,FOS,CASP4,ENPP1,WIPI1,P4HA2,GRAMD1C,PLIN3,F2RL1,HOOK1,XDH |
| 4.018e-05 | -10.12 | SENESE_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC2_TARGETS_DN | 114 | 26 | 17758 | 1761 |
MYL9,UNKL,FADS2,BCAM,TRIM2,DEPDC1,IGFBP6,S100A4,ZCCHC24,PKP2,NFIB,ALDH3B1,TNS3,SESN3,TIMP3,DACT1,MATN2,SORL1,NTN4,RTKN2,ETAA1,TMEM37,NPTXR,SCARA3,LRP11,SEMA3B |
| 4.026e-05 | -10.12 | single-organism catabolic process | biological process | GO:0044712 | 1004 | 141 | 16441 | 1675 |
GAA,AASS,CRYM,CPT2,HEXB,LMCD1,FBXO2,OAT,HDAC6,CALM2,TYMP,CYP1A1,PIK3CA,FUT1,ACOX2,APOBEC3G,CYP1B1,PLK1,SPATA18,CDA,SLC35C1,KLK6,CYP4F3,POR,COL12A1,PLCH1,ENPP1,PLCG1,NEIL1,HPSE,WIPI1,DHTKD1,GLA,NR2C2,MRC2,ALDH6A1,DNAJB2,CALM3,SLC1A3,ATG4A,GNS,RIMS3,FAM13B,BDH1,COL6A1,PCYOX1,PRKG1,AHCY,ALPK1,NCEH1,GAD1,PLCB2,MCCC2,CYP26B1,PRODH,CALM1,PDE5A,AMDHD1,MMP15,NUDT16,FAAH,COL13A1,MDH1,YOD1,PLD1,COL16A1,XDH,PLA2G4A,COL18A1,LPIN3,PRKACA,CYP39A1,CYP26A1,CYP4F11,FABP6,PLCG2,GOT1,PDE4D,PHKA2,NAGA,GM2A,CHP1,ATG4D,CTH,ENPP4,COL6A2,ERLEC1,SEC61B,ATP1B1,GABARAPL1,DNAJC10,DUOX1,ALDH3B1,ALDH5A1,ABHD12,WFS1,PEX2,PNPLA6,ADAMTS14,COL9A3,PINK1,ENO2,CIT,HAL,BLVRB,COL4A5,APOBEC3H,FBXO6,DNAJB9,SGPL1,ADORA1,FUT2,PTEN,FUT8,GALNS,UBE2J1,ADAM15,ECI2,ABCD1,ALDH7A1,FAH,ACBD5,HMMR,PGM1,ADAMTS2,SHMT1,ALDH2,GUSB,AMFR,OGDHL,FURIN,COL7A1,BLVRA,CTSL,FUCA1,ACADSB,PLOD2,PGM2L1,ARSB,WDR45B,ACOT7 |
| 4.034e-05 | -10.12 | STEIN_ESRRA_TARGETS | MSigDB lists | STEIN_ESRRA_TARGETS | 502 | 78 | 17758 | 1761 |
GAS2L1,ACACB,TRIM2,CEP70,UGP2,EPAS1,GNPDA1,VANGL1,RPS6KA1,TMX4,NDRG2,PRSS22,TEX2,NANS,ISOC2,MGST2,IER3,BTG3,CYP1A1,METTL7A,MITF,TRPC1,GOT1,MANF,EGLN3,SULT2B1,GM2A,CYP1B1,PPIF,TRIM8,SLC39A8,CASP9,HTATIP2,PRKAR2B,ARFRP1,ATP1B1,GABARAPL1,SLC25A4,WIPI1,ZNF165,RAP1GAP,LIFR,PPP2R2D,HLA-E,PDCL,GDF15,SCML1,CA2,CTSC,KCNN4,BMP7,FAM63A,OPN3,ECI2,ALDH3A2,TRAK2,GFPT1,OPLAH,PGM1,TACC1,PCTP,SPTLC2,CD83,EPN3,NUCB1,TJP3,ETS2,ACADSB,TIMM8A,SLC2A6,PRPS2,OTUB2,AURKA,MDH1,PLIN3,HOOK1,OCLN,EGLN1 |
| 4.051e-05 | -10.11 | SMIRNOV_RESPONSE_TO_IR_6HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_UP | 154 | 32 | 17758 | 1761 |
FAM169A,RAB23,GDF15,DSE,SDC1,DDR1,TNFSF9,LMNA,FZD6,SAC3D1,RABGGTA,IER3,APOBEC3B,FAM46A,METTL7A,DRAM1,CD70,F2R,MYBL1,LAMP3,DDB2,ADCK3,SESN1,RNF19B,CYP4F3,TP53I3,FAS,PGF,FUCA1,CSF1,PLK2,TOB1 |
| 4.056e-05 | -10.11 | membrane part | cellular component | GO:0044425 | 6439 | 720 | 17570 | 1756 |
IL15RA,SLC25A13,DNAJC3,RET,CACNA2D2,NRG2,LYNX1,TGOLN2,SYTL4,CMTM6,GRM5,SMIM13,CALM2,PQLC2,AP1M2,MUC4,CYP2S1,PAQR5,CABP1,FUT1,CLDN4,PIK3CD,TMEM37,RNF26,TIAM1,MGAT5,ERAP2,TMEM151A,PRKAR2B,ICMT,RNF19B,CYP4F3,ARF4,ENPP1,DNM1L,ATP7B,NOD2,RELL1,ARF6,SCN5A,GGA1,ITGA6,SLC36A4,COX6C,FAM21C,MERTK,TTYH3,MARCH8,FAM189A1,MEGF8,ATP5H,FLRT3,PANX2,NCAM1,MYLIP,ULBP2,NDUFA12,NUP85,PAQR7,SLC37A1,PQLC3,ERO1A,SPTLC2,GNA11,SFXN5,CYB5A,PTPRF,SCARB2,CACHD1,SLC4A4,SEMA4D,ITPR1,RAET1L,CLMN,STK39,MAL2,TMEM159,RUSC1,TMEM173,CCDC109B,GALNT12,CD82,PKP2,IL13RA1,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,CDS1,MUC16,SCNN1A,CDH1,XYLT2,ENPP5,ACSL4,DLG3,LRP11,RAB27B,SNX10,TMEM9,SCN3A,TMEM200B,MX1,ENPP4,SEC61B,FZD4,SYNE2,CYS1,DNAJB14,SNX12,COX20,GABARAPL1,SHROOM3,SLC9A6,WFS1,AXL,CORO1C,SIPA1L1,PNPLA6,TRABD2A,PRIMA1,RGS14,SLC25A30,TTC8,SDC4,BTN3A1,ANO9,PLPPR4,SLC25A43,SRPX2,SGPL1,NEO1,CXCL16,FUT2,IGSF9,ITGB8,SLC27A6,ANKS1B,ALG13,MGAT4A,FAM20B,BAX,ADAM15,TMBIM6,IGFBP2,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,PVRL4,ACBD5,PLSCR1,RAPGEF2,EIF5A2,MFSD2B,ELOVL3,PIK3R1,MRS2,GRIN1,SNTB1,CNTNAP1,GALNT3,PLOD2,ACVRL1,SYT7,ITGAV,WDR45B,DCBLD1,CYBRD1,TMEM131,SIGIRR,BCAM,ILDR1,EPHA4,F11R,TEX2,ITPR2,TP53I11,MGAT5B,HDAC6,PDGFB,SDC1,SPTB,SUSD2,NPNT,IL6ST,SLC44A1,TMEM143,ABCA2,SCARA3,ANO4,TRAM1,SMAGP,CD55,KCNIP3,MCTP1,CELSR2,NFE2L1,CR2,EZR,LHFPL2,RHEB,TMEM164,MFAP3L,HS6ST1,KCNMB4,AGPAT2,WIPI1,DOLPP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,RRAGD,PRSS8,LMTK3,LGALS3,RASA2,FXYD3,HLA-F,SLC22A31,ADCK5,CNTNAP2,NCKAP1,B4GALT4,C3orf18,DHRS3,IL18R1,ANO1,B4GALNT1,IGF1R,FRAS1,TBCD,SELK,FAR2,ALDH3A2,CKAP4,ABCC1,CYP26B1,CHSY3,PCDH1,RGMB,BTNL9,MGAT4B,SPATA13,EMC2,SCRIB,RASGRP2,EPN3,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,SLC2A6,ZDHHC7,PLD1,ATP1B3,TMEM120A,IFI6,SMCO4,NIPA1,NF2,TMX4,XYLT1,ERBB2,FAM198B,SLC7A2,LPIN3,EMP2,BCAP31,CYP26A1,SYTL2,IER3,ATP6V0B,ZDHHC23,VAT1,CDH3,NOTCH3,TMEM64,SCN2A,LMAN1,GM2A,PPIF,CPD,TMTC1,CLCN3,EVA1A,PTGER4,DAG1,ATP13A2,DUOX1,TAPBP,ATP1A1,PRRT4,PTPRJ,ABHD12,PTK7,MMP17,EFNA5,SYT13,C1orf43,ST3GAL1,TMEM263,NDST3,CMTM4,ARFGEF3,BIN1,PINK1,MFSD14B,PACSIN2,GOLIM4,TM2D2,TOR4A,CDH22,CD63,ADGRG1,SELL,GABRG2,DSE,LBR,FZD6,PARM1,VPS26A,SLC9A2,DNAJB9,SIRPA,NRP2,M6PR,ZDHHC21,CD109,ALPP,CDK16,UBE2J1,SGK1,TSPAN13,ABCD1,SYK,ATP2B1,GCNT1,IGDCC4,DLGAP1,RHOA,MOSPD2,IFITM3,CRB3,PLAUR,AMFR,FNDC3A,BBS2,TXNDC11,MAPK8IP1,DGKE,CD83,FAT4,TMC5,NETO2,PGRMC1,SPCS3,ICOSLG,FER1L4,NDFIP1,PTGES,ARHGEF4,GOLGB1,LAMP1,SUN1,SLC35D2,LGR4,VANGL1,TMEM41B,ATP8A1,TAP1,PLXNA1,PJA2,SLC20A1,NCS1,SLC9A7,CYP1A1,STIM1,IL31RA,PIK3CA,SERINC2,KCNS3,STEAP2,ATRNL1,SNX16,TACSTD2,MARCH2,ARMCX6,PACSIN1,XKR8,LAMP2,SGCE,ORAI2,TMEM68,ACVR1C,SNTB2,SLC35C1,GALNT7,MCFD2,SLC25A5,POR,SPNS3,SLC25A4,GDE1,GNPTAB,LRIG1,SARAF,UNC5B,F2RL1,TRAF5,LZTS1,DDX58,SEMA6B,MRC2,HLA-E,TMEM55B,SLC25A27,NDUFA4,SLC1A3,TNFRSF19,TSPAN7,PRRG4,KIAA1161,C9orf69,ITGA3,ZNRF2,LYPD3,SNX18,VASN,SLC16A6,TMEM51,ADCK2,OPN3,TPST1,SORL1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,SYTL3,GPR161,RIMS2,IGSF3,FAM69A,EPB41L5,FADS2,PMPCB,B3GNT7,KCNJ12,MFI2,MMD,ADCK3,MICB,LPGAT1,CALM1,ANO6,VEZT,ATP8B3,EPHA1,ANTXR1,GLT8D2,STX3,RASA1,FAS,MMP15,SLCO4A1,GABRD,TMEM54,TJP3,FAAH,SLC4A3,PCDH19,MAP3K5,HOOK1,EHD1,MFSD3,PLA2G4A,SPRED1,SLC2A4,TCTN2,ARMCX3,TRIP10,ST14,IQGAP1,ATP2C2,RNF182,KCTD12,BCL2L1,TMEM170B,CD274,SNN,AIFM2,DDR1,TMPRSS4,CYP39A1,EPS8L2,APLP2,BRI3,CNNM4,DAB2IP,EPHB4,PDE4D,TSPAN1,SEC23A,PANK1,UTRN,TMEM144,PRKCQ,SLC11A2,PKMYT1,ATP1B1,ITPR3,TRIQK,ALCAM,ATP10D,FZD7,CMTM7,EPHA10,JAK1,DDOST,POPDC3,STK26,TSPAN18,SLC27A1,NRG1,HS3ST3B1,SLC27A3,NR3C2,DENND5B,ATP9A,EPS8,EFHD2,CYB561,EFNB1,ADGRB2,HLA-A,SLC25A36,TMCC3,SNTA1,TMEM87B,RNF128,PTEN,FUT8,CD9,DRAM1,SLC44A2,ATP8B1,ERBB3,SPRY2,SLC16A5,FARP2,B3GNT2,ERMAP,MPP1,FURIN,C1GALT1C1,YES1,AIF1L,CPTP,NUCB1,MAMDC4,FGFR2,ABCB1,RYK,ERAP1,GRIN2D,GPER1,FZD5,SLC25A38,OCLN,ESYT2,RGMA,CASP3,UGT8,CACNB4,SLC8B1,DNER,KREMEN1,TMC1,PTCHD4,CHPF,HTR1D,ABCD4,NKAIN3,EPCAM,TSPAN6,IMPAD1,DLG1,TRPC1,SUN3,RP2,CTTN,TECR,SLC39A10,PTPRE,MYRIP,RASGRP1,LAMP3,CYP1B1,ATL1,ROR1,PTGFRN,EDNRA,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ADIPOR1,LEMD1,STARD3NL,PCSK5,CD99,SERPINE2,BVES,ABCG2,CALM3,TEC,B3GALNT1,CA2,KCNN4,SUCO,FXYD5,HLA-C,C10orf54,NCEH1,SLC12A2,KDELR1,SNX7,PODXL2,GYLTL1B,BTN3A2,MFSD7,C3orf58,STEAP1,GLCE,GNAS,XKRX,SLC6A6,PLPP3,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TMEM14A,APOL2,RARG,SNX30,PROM2,SLC25A24,SORBS1,IL15,PDIA5,IL27RA,SLC25A48,CYP4F11,ZDHHC12,REEP1,RPN2,ECE1,EPB41L4B,F2R,PDIA6,SUSD3,PTPRU,OSTM1,SLC39A8,C3orf52,IGSF8,ERBB2IP,CD40,CASP4,PEX2,SECTM1,VSIG10,SPTBN5,CYP2U1,REEP4,ABCA1,LIFR,SORT1,TSPAN15,LRP4,FAM134A,TGFBR1,POMGNT1,SBF1,TMEM63A,IL17RB,ADORA1,A4GALT,RRBP1,KIAA0319,IQGAP3,B3GALT6,SYPL1,SUN2,TMEM245,SYBU,LRRC66,LEPR,HLA-B,CTSV,SPINT2,ARRB1,MCUR1,GRAMD1C,GEM,PLOD3,L1CAM,CD33,ABCG1,SNPH |
| 4.089e-05 | -10.10 | regulation of stress-activated MAPK cascade | biological process | GO:0032872 | 191 | 38 | 16441 | 1675 |
PINK1,FOXM1,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,CTGF,IGF1R,DACT1,MAP3K9,DLG1,DUSP10,DAB2IP,MDFIC,SYK,DVL2,RASGRP1,MDFI,MAP3K3,AKT1,RIPK2,FZD4,PBK,ITCH,EZR,MAP3K6,MAPK8IP1,FZD7,ANKRD6,NOD2,MAP3K5,FZD5,F2RL1,GAB1,HIPK3,XDH |
| 4.135e-05 | -10.09 | MODULE_105 | MSigDB lists | MODULE_105 | 196 | 38 | 17758 | 1761 |
WASF3,FOXM1,DAP,FXYD3,COL18A1,CCNB1,SLC20A1,ERP29,WEE1,CTGF,CYR61,RGS3,LMO4,PPP4R1,NEK2,TUBG1,CDH3,CITED2,S100A13,ATP2B1,CKS2,CYP1B1,CENPA,MMD,COG2,LPGAT1,FURIN,MYBL2,GGH,CCNF,ITPR3,ALCAM,CDK1,KCNK1,HSPB1,AHR,MELK,ACOT7 |
| 4.140e-05 | -10.09 | DORN_ADENOVIRUS_INFECTION_24HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_24HR_DN | 43 | 14 | 17758 | 1761 |
BCAR3,TOP2A,CCND1,CYR61,RND3,H1F0,NR4A1,PLK2,NFKBIA,SGK1,TNFRSF12A,COL7A1,CD83,IER3 |
| 4.140e-05 | -10.09 | AMIT_EGF_RESPONSE_60_HELA | MSigDB lists | AMIT_EGF_RESPONSE_60_HELA | 43 | 14 | 17758 | 1761 |
CCND1,HES1,CTGF,PLSCR1,CYR61,FOSB,NR4A3,NR4A2,RUNX3,NCKAP1,CITED2,SLC20A1,TIPARP,ATG4A |
| 4.140e-05 | -10.09 | NAKAMURA_CANCER_MICROENVIRONMENT_DN | MSigDB lists | NAKAMURA_CANCER_MICROENVIRONMENT_DN | 43 | 14 | 17758 | 1761 |
TNS3,ARTN,RIPK2,SHROOM3,IMPAD1,CDC20,FAM83D,AURKA,BUB1,CDCA2,DHRS3,CCNB2,FANCI,CTH |
| 4.140e-05 | -10.09 | STREICHER_LSM1_TARGETS_UP | MSigDB lists | STREICHER_LSM1_TARGETS_UP | 43 | 14 | 17758 | 1761 |
IL15RA,GATA2,FGFR2,RBL1,INPP4B,BCL6,IL13RA1,CITED2,PDGFB,HSPB1,NR3C2,FZD7,ELF3,SOX13 |
| 4.177e-05 | -10.08 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | 189 | 37 | 17758 | 1761 |
ANXA3,LTBP1,ZCCHC24,COL4A5,MORF4L2,SRPX2,TEAD3,PDGFA,SS18,RPS6KA2,IMPAD1,RRBP1,TPST1,TWIST1,TNFRSF12A,MTMR11,ALDH3A2,GFPT1,LAMP2,COL6A2,OSTM1,PIP4K2C,MCFD2,ATP10D,LEPR,TP53I3,GLT8D2,CRISPLD2,EDNRA,STK17A,DNAJC10,GPRC5B,SLC25A4,KCNK1,FGD6,CTSA,PLOD3 |
| 4.177e-05 | -10.08 | GSE10325_CD4_TCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_DN | 189 | 37 | 17758 | 1761 |
NFKBIE,REPS2,CDKN1C,RUSC2,HEXB,IL13RA1,DSE,SIRPA,APLP2,TNS3,METTL7A,PLCG2,OPN3,BCL6,MTMR11,SNX10,DGKG,SYK,GM2A,CCDC88A,CYP1B1,GCNT1,ALDH2,PLAUR,SAT1,PLEKHO1,RNPEP,LHFPL2,ADRBK2,ATP10D,RBM47,PRCP,CORO1C,SLC2A6,FAM114A1,ZDHHC7,LTA4H |
| 4.177e-05 | -10.08 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 189 | 37 | 17758 | 1761 |
LTBP1,COL9A3,DEPDC1,TSC22D3,HEBP1,CALB2,EPS8,OSR2,HERC6,STIL,RCN1,BTG3,ADD3,IGF1R,LLGL2,ALG13,BDH1,ELF5,PCYOX1,SGK3,SGCB,RASGRP1,SNX7,ENPP4,CYP26B1,CELSR2,MICB,SLC39A8,KIF11,MDK,PDLIM3,MATN2,ANXA9,NCAPG2,SLC27A3,E2F8,IFI6 |
| 4.177e-05 | -10.08 | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | MSigDB lists | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | 189 | 37 | 17758 | 1761 |
DDX58,PARP12,GNPDA1,PSME2,TAP1,HERC5,SAMD9,HERC6,LGALS3BP,SAC3D1,DTX3L,PIK3AP1,METTL7A,IFIT1,OAS3,ALDH3A2,PARP9,LAMP3,MX1,IFITM3,USP18,MBNL3,BLVRA,SNTB1,IFIT3,IDH1,ATP10D,GLCE,SCARB2,IDE,TRIM69,IRF7,CMPK2,SLC27A3,IFIH1,IFI6,CPPED1 |
| 4.177e-05 | -10.08 | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | 189 | 37 | 17758 | 1761 |
SLC35D2,TRIM2,ADD1,S100A11,CENPI,PTTG1,HEXB,NDRG2,PSIP1,GNS,OTUD1,CYP1A1,GRHL1,RINL,TNFRSF12A,TAGLN2,TMEM64,C12orf75,TPCN1,SEC23A,CASP9,SPATA13,CCDC34,NEURL1B,STK17B,SNX12,PIAS3,NUDT16,DNAJC10,FAM114A1,S100A5,DTX4,PGM2L1,SPCS3,CBX7,SNX30,KLF7 |
| 4.196e-05 | -10.08 | STK33_NOMO_UP | MSigDB lists | STK33_NOMO_UP | 269 | 48 | 17758 | 1761 |
SPRED1,CPEB4,EPAS1,FAM199X,NUAK1,DDIT4L,SDC4,FAM134A,ARL4C,GDF15,FAM198B,MERTK,PHLDA1,SGPL1,IER3,SIPA1L2,OTUD1,BTG3,IL6ST,ZFP36,DAPK1,BCL6,ANKRD12,SGK1,NCEH1,GFPT1,DOCK4,TGIF1,OSTM1,COQ10B,MGAT4B,SLC11A2,YES1,FNDC3A,PTGFRN,FOS,STK17B,RND3,NR1D2,SEMA4D,SCG2,UEVLD,LIMK1,FAM114A1,TMEM159,ST3GAL1,MAFF,ABCA1 |
| 4.200e-05 | -10.08 | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | 182 | 36 | 17758 | 1761 |
DDX58,ANXA3,PACSIN2,DNAJC3,RET,NDRG2,FTH1,SLC20A1,PHLDA1,PRRG4,SCML1,MLPH,CTGF,BCL6,GLB1L2,ALPK1,SEMA3G,MYO5A,XKR8,RHOA,LONRF3,LPGAT1,CDA,MSL1,SLC4A4,AGPAT2,PVRL2,P4HA2,SECTM1,SIPA1L1,CLMN,ADIPOR1,PTGES,CPPED1,EHD1,GOLGB1 |
| 4.201e-05 | -10.08 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | 175 | 35 | 17758 | 1761 |
BIN1,UBASH3B,ITGA6,TDRKH,SYTL4,SNN,EPS8L2,H1FX,OTUD1,FAM111A,ANKS6,GALNS,TAGLN2,PIM1,DLG3,CITED2,SLC16A5,FBXL16,KIFC2,MMD,BLVRA,LDB2,FOS,TYSND1,SOCS3,ANKRD10,IRS2,ARRB1,NFKBIZ,KLF11,PIEZO1,ZMIZ1,NRGN,TOB1,MAFF |
| 4.229e-05 | -10.07 | HECKER_IFNB1_TARGETS | MSigDB lists | HECKER_IFNB1_TARGETS | 89 | 22 | 17758 | 1761 |
DDX58,MYL9,MX1,PARP12,PLSCR1,HERC5,SAMD9,IFIT3,HERC6,CYP4F3,LGALS3BP,APOBEC3B,DTX3L,TYMP,SH3BGRL2,IRF7,IFIT1,OAS3,CMPK2,IFI6,PARP9,LAMP3 |
| 4.254e-05 | -10.06 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3979 | 460 | 17775 | 1757 |
HECA,PPP4R4,ADD1,LGR4,IL15RA,AASS,VANGL1,ATP8A1,TSC22D3,CACNA2D2,LYNX1,PLXNA1,VASH1,CA8,FAM46C,SLC20A1,CMTM6,LTBP3,EPDR1,CDKN2C,DAPK2,PQLC2,CTGF,IQCE,PAQR5,PIK3CA,ATRNL1,IRF2,PIK3CD,TMEM37,TIPARP,ERAP2,DNAAF3,METAP2,SPATA18,ACVR1C,HSPA12A,NBPF3,PRKAR2B,KIF13A,TNS1,LOXL2,LDB2,PPP1R14C,CCNF,RNF19B,SLC25A5,COL12A1,ARHGEF26,AHRR,ENPP1,DNM1L,GDE1,ATP7B,NKD1,TRAF3IP1,NOD2,PRDM5,BMP1,MRPS28,UNC5B,GAB1,SCN5A,MRC2,CDK17,FRMD4A,TBC1D1,SOX9,DGKQ,SLC1A3,KIAA1161,ELF3,ATG4A,DOPEY2,RALGPS2,FAM189A1,MEGF8,SLC16A6,BDH1,RUNDC3B,PRKG1,MAP3K9,SORL1,CADPS2,CACNA1D,NCAM1,NUP85,RIMS2,TRAK2,B3GNT7,KCNJ12,HPS3,SLC37A1,MFI2,STAT4,AMER1,MYBL2,ELK1,NPHP3,NFIB,DCP2,STX3,RASA1,MMP15,PTPRF,DGKH,CACHD1,PRKAG2,SLC4A4,SETD3,DCK,ITPR1,CABIN1,FBXO27,PLIN3,PER3,HOOK1,IFIH1,XDH,DOCK9,ARHGAP11A,PLA2G4A,FRMPD3,MTM1,TPRN,SLC2A4,GRHL2,DLGAP5,TMSB15A,ST14,ACTR8,PKP2,PRSS22,TMEM170B,CYP39A1,ZNF385B,CDS1,NOV,MUC16,RNF220,CNNM4,DAB2IP,IFIT1,ARL4D,LGMN,MYT1,MYO5B,SSH3,CAPN6,CYB5R2,DRAP1,SEPT6,SYNE2,UTRN,HTATIP2,CDCA2,PRKCQ,ATP1B1,ITPR3,ZNF618,PRDM11,PDLIM3,JAK1,POPDC3,SHROOM3,SIPA1L1,INPP4B,NRG1,MLKL,NR3C2,COBL,MAPK12,DENND5B,TTC8,WASF3,ATP9A,CCNJL,PBX3,ANO9,DNAH3,BEX2,HLA-A,TMCC3,SCML1,DTX3L,FAM111A,ADD3,ITGB8,SLC27A6,PHF7,ANKS1B,PTEN,CALD1,ALG13,DRAM1,CD9,ECI2,SLC44A2,WWP1,CNOT6L,ADAMTS2,PDGFC,ARHGEF28,LONRF3,FMN1,PIK3R1,GRIN1,PARP4,AK4,DIAPH2,FBXO9,LRRC1,SNTB1,CNTNAP1,GALNT3,PLOD2,FGFR2,NR1D2,ABCB1,PPM1H,CENPE,ARSB,USF2,CPEB2,DCBLD1,ACOT7,MELK,TLL2,TMEM131,ESYT2,JARID2,EXPH5,UNKL,LTBP1,UGT8,EPAS1,EPHA4,CUL4B,FHDC1,TEX2,VARS2,ITPR2,DNER,CACNB4,TMC1,SPTB,SH3KBP1,PLS3,CHPF,HTR1D,ARHGEF10L,NKAIN3,RAB15,SIPA1L2,SHC3,NPNT,DPYSL2,IL6ST,PHTF1,ELF5,MITF,DLG1,TMEM143,ABCA2,ANKRD12,TRPC1,NTN4,RP2,CTTN,MYH14,ANO4,TLN2,MYRIP,NEB,ZNF462,THRB,MCTP1,CELSR2,RGAG1,KLK6,ROR1,ANLN,IDH1,SESN1,PTGFRN,ADRBK2,DZIP1L,DPYSL3,LRRC42,PLEKHG6,MFAP3L,NEIL1,KLF12,KCNK1,MAP2,MADD,KLF11,PIEZO1,EPB41L4A,GLCCI1,RRAGD,GRN,CD99,UBASH3B,CNTNAP2,NCKAP1,PHLPP1,ADAMTSL4,B4GALNT1,TNS3,IGF1R,GATA2,FRAS1,KIF13B,COL6A1,MDFIC,LIMCH1,C10orf54,SLC12A2,PLCB2,ALDH3A2,ALS2CL,DPYSL5,CHSY3,PLEKHA6,PDE5A,CDK5R1,BCAR3,MAPKAPK2,ONECUT1,SLC6A6,PVRL2,MFSD2A,PHLPP2,P4HA3,NLRC5,PLD1,ATP1B3,SHROOM2,SEMA3A,JAK3,RARG,AFAP1,SNX30,PROM2,USP43,LMO7,GAS2L1,NCKAP5,NF2,TMX4,TP53,PDIA5,CCDC68,COL18A1,ERBB2,IL27RA,TTC21B,LRRC45,ZNF687,EFR3A,CYP4F11,PLCG2,GLB1L2,ESPN,EPB41L4B,NOTCH3,EGLN3,PDIA6,SEPHS1,SULF2,CPD,PPIF,TMTC1,GCA,AKT1,PTPRU,DOCK5,ARHGAP35,DUOX1,IDE,PTPRJ,ADAMTS14,TLE1,VSIG10,SPTBN5,EFNA5,SYT13,LTA4H,AIFM3,ABCA1,NDST3,LNP1,LIFR,CMTM4,MAN2B2,BIN1,GLIS3,FBLIM1,CDH22,CPEB4,MACC1,DAP,LRP4,HAL,CDCA8,GABRG2,MIER3,COL4A5,POMGNT1,SLC9A2,NRP2,HDAC9,CD109,MLPH,CDK16,ALPP,BMP7,TOX2,GALNS,TFAP2A,FAM63A,GTF2F2,IQGAP3,C12orf75,SYK,MYO5A,ATP2B1,DLGAP1,PGM1,SUN2,FBLN5,IFITM3,NR3C1,DEPDC4,GCLC,ASPM,RC3H2,OGDHL,TTC7A,PRICKLE1,MAML2,COL7A1,BCAR1,FOXL1,KLHL2,BANK1,SWAP70,FAT4,NAT1,SPINT2,OTUB2,UACA,ARRB1,SH3BGRL2,GRAMD1C,ZMIZ1,L1CAM,ABCG1,GOLGB1 |
| 4.254e-05 | -10.06 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3979 | 460 | 17775 | 1757 |
HECA,PPP4R4,ADD1,LGR4,IL15RA,AASS,VANGL1,ATP8A1,TSC22D3,CACNA2D2,LYNX1,PLXNA1,VASH1,CA8,FAM46C,SLC20A1,CMTM6,LTBP3,EPDR1,CDKN2C,DAPK2,PQLC2,CTGF,IQCE,PAQR5,PIK3CA,ATRNL1,IRF2,PIK3CD,TMEM37,TIPARP,ERAP2,DNAAF3,METAP2,SPATA18,ACVR1C,HSPA12A,NBPF3,PRKAR2B,KIF13A,TNS1,LOXL2,LDB2,PPP1R14C,CCNF,RNF19B,SLC25A5,COL12A1,ARHGEF26,AHRR,ENPP1,DNM1L,GDE1,ATP7B,NKD1,TRAF3IP1,NOD2,PRDM5,BMP1,MRPS28,UNC5B,GAB1,SCN5A,MRC2,CDK17,FRMD4A,TBC1D1,SOX9,DGKQ,SLC1A3,KIAA1161,ELF3,ATG4A,DOPEY2,RALGPS2,FAM189A1,MEGF8,SLC16A6,BDH1,RUNDC3B,PRKG1,MAP3K9,SORL1,CADPS2,CACNA1D,NCAM1,NUP85,RIMS2,TRAK2,B3GNT7,KCNJ12,HPS3,SLC37A1,MFI2,STAT4,AMER1,MYBL2,ELK1,NPHP3,NFIB,DCP2,STX3,RASA1,MMP15,PTPRF,DGKH,CACHD1,PRKAG2,SLC4A4,SETD3,DCK,ITPR1,CABIN1,FBXO27,PLIN3,PER3,HOOK1,IFIH1,XDH,DOCK9,ARHGAP11A,PLA2G4A,FRMPD3,MTM1,TPRN,SLC2A4,GRHL2,DLGAP5,TMSB15A,ST14,ACTR8,PKP2,PRSS22,TMEM170B,CYP39A1,ZNF385B,CDS1,NOV,MUC16,RNF220,CNNM4,DAB2IP,IFIT1,ARL4D,LGMN,MYT1,MYO5B,SSH3,CAPN6,CYB5R2,DRAP1,SEPT6,SYNE2,UTRN,HTATIP2,CDCA2,PRKCQ,ATP1B1,ITPR3,ZNF618,PRDM11,PDLIM3,JAK1,POPDC3,SHROOM3,SIPA1L1,INPP4B,NRG1,MLKL,NR3C2,COBL,MAPK12,DENND5B,TTC8,WASF3,ATP9A,CCNJL,PBX3,ANO9,DNAH3,BEX2,HLA-A,TMCC3,SCML1,DTX3L,FAM111A,ADD3,ITGB8,SLC27A6,PHF7,ANKS1B,PTEN,CALD1,ALG13,DRAM1,CD9,ECI2,SLC44A2,WWP1,CNOT6L,ADAMTS2,PDGFC,ARHGEF28,LONRF3,FMN1,PIK3R1,GRIN1,PARP4,AK4,DIAPH2,FBXO9,LRRC1,SNTB1,CNTNAP1,GALNT3,PLOD2,FGFR2,NR1D2,ABCB1,PPM1H,CENPE,ARSB,USF2,CPEB2,DCBLD1,ACOT7,MELK,TLL2,TMEM131,ESYT2,JARID2,EXPH5,UNKL,LTBP1,UGT8,EPAS1,EPHA4,CUL4B,FHDC1,TEX2,VARS2,ITPR2,DNER,CACNB4,TMC1,SPTB,SH3KBP1,PLS3,CHPF,HTR1D,ARHGEF10L,NKAIN3,RAB15,SIPA1L2,SHC3,NPNT,DPYSL2,IL6ST,PHTF1,ELF5,MITF,DLG1,TMEM143,ABCA2,ANKRD12,TRPC1,NTN4,RP2,CTTN,MYH14,ANO4,TLN2,MYRIP,NEB,ZNF462,THRB,MCTP1,CELSR2,RGAG1,KLK6,ROR1,ANLN,IDH1,SESN1,PTGFRN,ADRBK2,DZIP1L,DPYSL3,LRRC42,PLEKHG6,MFAP3L,NEIL1,KLF12,KCNK1,MAP2,MADD,KLF11,PIEZO1,EPB41L4A,GLCCI1,RRAGD,GRN,CD99,UBASH3B,CNTNAP2,NCKAP1,PHLPP1,ADAMTSL4,B4GALNT1,TNS3,IGF1R,GATA2,FRAS1,KIF13B,COL6A1,MDFIC,LIMCH1,C10orf54,SLC12A2,PLCB2,ALDH3A2,ALS2CL,DPYSL5,CHSY3,PLEKHA6,PDE5A,CDK5R1,BCAR3,MAPKAPK2,ONECUT1,SLC6A6,PVRL2,MFSD2A,PHLPP2,P4HA3,NLRC5,PLD1,ATP1B3,SHROOM2,SEMA3A,JAK3,RARG,AFAP1,SNX30,PROM2,USP43,LMO7,GAS2L1,NCKAP5,NF2,TMX4,TP53,PDIA5,CCDC68,COL18A1,ERBB2,IL27RA,TTC21B,LRRC45,ZNF687,EFR3A,CYP4F11,PLCG2,GLB1L2,ESPN,EPB41L4B,NOTCH3,EGLN3,PDIA6,SEPHS1,SULF2,CPD,PPIF,TMTC1,GCA,AKT1,PTPRU,DOCK5,ARHGAP35,DUOX1,IDE,PTPRJ,ADAMTS14,TLE1,VSIG10,SPTBN5,EFNA5,SYT13,LTA4H,AIFM3,ABCA1,NDST3,LNP1,LIFR,CMTM4,MAN2B2,BIN1,GLIS3,FBLIM1,CDH22,CPEB4,MACC1,DAP,LRP4,HAL,CDCA8,GABRG2,MIER3,COL4A5,POMGNT1,SLC9A2,NRP2,HDAC9,CD109,MLPH,CDK16,ALPP,BMP7,TOX2,GALNS,TFAP2A,FAM63A,GTF2F2,IQGAP3,C12orf75,SYK,MYO5A,ATP2B1,DLGAP1,PGM1,SUN2,FBLN5,IFITM3,NR3C1,DEPDC4,GCLC,ASPM,RC3H2,OGDHL,TTC7A,PRICKLE1,MAML2,COL7A1,BCAR1,FOXL1,KLHL2,BANK1,SWAP70,FAT4,NAT1,SPINT2,OTUB2,UACA,ARRB1,SH3BGRL2,GRAMD1C,ZMIZ1,L1CAM,ABCG1,GOLGB1 |
| 4.291e-05 | -10.06 | RHOA (ras homolog family member A) | protein interactions | 387 | 143 | 32 | 16036 | 1726 |
ARHGEF3,ARHGEF11,CIT,DGKQ,PSMD10,TGFBR1,PKN1,PRKACA,DIRAS3,SH3BP1,DPYSL2,TRPC1,CDKN1B,RPN2,DVL2,RASGRF1,RHOA,ARHGEF28,EZR,ARHGDIB,ICMT,SLC25A5,ARHGAP35,FAS,CNTNAP1,PLCG1,NFKBIA,ITPR1,PLD1,PLIN3,DEF6,ARHGEF4 |
| 4.304e-05 | -10.05 | SHEPARD_BMYB_TARGETS | MSigDB lists | SHEPARD_BMYB_TARGETS | 71 | 19 | 17758 | 1761 |
PHF20L1,DLGAP5,FOXM1,CKAP2,ASPM,CDC20,KIF23,CDCA2,CCNB1,ANLN,KIF11,CDK1,MDK,ATP1A1,KIF14,HMGA1,NDE1,MELK,GOLGB1 |
| 4.307e-05 | -10.05 | ELLWOOD_MYC_TARGETS_DN | MSigDB lists | ELLWOOD_MYC_TARGETS_DN | 38 | 13 | 17758 | 1761 |
DNAJC10,NKX3-1,ALDH2,IDE,CA2,NR1D2,PEX2,CLDN4,EZR,LIMCH1,MCFD2,PDIA6,TP53INP2 |
| 4.316e-05 | -10.05 | MODULE_456 | MSigDB lists | MODULE_456 | 108 | 25 | 17758 | 1761 |
CCNE2,MMD,FAM169A,STAT4,PTGER4,CR2,PRKAR2B,PIF1,TRIB2,ASB13,TSPAN7,CD83,CDKN2C,SWAP70,PTK7,IL6ST,A4GALT,BMP7,NFKBIA,NR4A3,BCL6,SORL1,IFIT1,OAS3,MYBL1 |
| 4.331e-05 | -10.05 | GNF2_SMC4L1 | MSigDB lists | GNF2_SMC4L1 | 83 | 21 | 17758 | 1761 |
HMMR,ZWINT,DLGAP5,FOXM1,CKAP2,ASPM,CDC20,NDC80,CDCA8,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,PLK4,AURKA,CCNB2,E2F8,METAP2,CKS2 |
| 4.340e-05 | -10.05 | regulation of body fluid levels | biological process | GO:0050878 | 666 | 100 | 16441 | 1675 |
PLA2G4A,MYL9,PAPSS2,INPP5D,TP53,F11R,ITPR2,PRKACA,DDR1,PDGFB,EMP2,PDGFA,CALM2,CCND1,WEE1,SCNN1A,STIM1,CYP4F11,PLCG2,PIK3CA,CLDN4,TRPC1,IRF2,LMAN1,F2R,RASGRP1,MYO5B,LAMP2,ENPP4,CELSR2,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,KCNMB4,ABHD12,AXL,WFS1,ATP7B,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SELL,KIF23,CALM3,FBLN1,MERTK,FZD6,SIRPA,ITGA3,ADORA1,GATA2,KCNN4,CD9,PRKG1,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RASGRP2,DGKH,GNAS,SERPINA1,RAB11FIP2,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,USF2,L1CAM,DOCK9,EHD1,XDH |
| 4.367e-05 | -10.04 | neural tube closure | biological process | GO:0001843 | 87 | 22 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 4.367e-05 | -10.04 | regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0000079 | 87 | 22 | 16441 | 1675 |
PLK1,CCNE2,CASP3,AKT1,RGCC,HERC5,PSMD10,PKMYT1,PDGFB,STIL,CDK5R1,CCND1,CDK5RAP1,DIRAS3,CDKN2C,TFAP4,PTEN,CDKN1B,PIM1,CDKN2D,UBE2C,CKS2 |
| 4.437e-05 | -10.02 | REACTOME_COLLAGEN_FORMATION | MSigDB lists | REACTOME_COLLAGEN_FORMATION | 54 | 16 | 17758 | 1761 |
COL9A3,ADAMTS2,PCOLCE,COL6A2,COL4A5,COL7A1,COL12A1,PLOD2,COL13A1,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 4.468e-05 | -10.02 | MULLIGHAN_MLL_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_UP | 400 | 65 | 17758 | 1761 |
ARHGAP11A,LAMP1,PLA2G4A,GAA,IQGAP1,RPS6KA1,HEXB,TGOLN2,GRK6,ISOC2,MGST2,HDAC6,REPS1,DENND2D,IQCE,SNX10,NAGA,PPIF,LAMP2,PTPN9,S100A4,HTATIP2,C15orf39,RNF19B,ABR,ALDH3B1,RBM47,HOXA9,SLC9A6,EIF4EBP2,RGS14,SLC27A3,NRGN,GRN,ARHGEF3,PPP1R2,RASSF7,EFHD2,PBX3,RAB6A,ARHGEF40,SIRPA,PRRG4,SAC3D1,M6PR,GNS,TNS3,TAF1B,TBCD,RRBP1,CNPY3,ALDH3A2,SYK,S100A6,PLAUR,PIP4K2C,RNPEP,MAPKAPK2,ITGA7,SFMBT1,CTSA,PITPNA,PLIN3,ARPC2,ESPL1 |
| 4.488e-05 | -10.01 | biological adhesion | biological process | GO:0022610 | 1040 | 145 | 16441 | 1675 |
MYL9,BCAM,KIAA1462,EPHA4,RET,F11R,EPDR1,EPCAM,MUC4,CTGF,NPNT,ELMO2,DLG1,CLDN4,PIK3CD,TINAGL1,CTTN,TLN2,TIAM1,SMAGP,CYP1B1,SGCE,CELSR2,TNIP1,EZR,LOXL2,COL12A1,HPSE,ARF6,HSPB1,F2RL1,CD99,RUNX2,BVES,THEMIS2,NUAK1,ITGA6,HLA-E,SOX9,CNTNAP2,MERTK,IL18R1,ITGA3,CYR61,LYPD3,FLRT3,KIF13B,COL6A1,TNFRSF12A,NCAM1,WNT3A,EPB41L5,PODXL2,PCDH1,RGMB,MICB,SCRIB,VEZT,EPHA1,ANTXR1,CDK5R1,FAS,GNAS,PTPRF,SCARB2,PVRL2,SEMA4D,COL13A1,PLPP3,ITGA7,CGREF1,PCDH19,EGFL7,COL16A1,SORBS1,GRHL2,IL15,TP53,TESK2,PKP2,COL18A1,EMP2,DDR1,NOV,MUC16,CDH1,KIF14,CDH3,EPHB4,CAMSAP3,COL6A2,RIPK2,FZD4,PTPRU,PTGER4,ERBB2IP,ATP1B1,ALCAM,DAG1,MYL12A,FZD7,DDOST,AXL,PTK7,ANXA9,FBLIM1,CDH22,HAPLN3,ADGRG1,CD63,GNE,SELL,BTN3A1,EFNB1,SRPX2,LGALS3BP,NRP2,SIRPA,NEO1,IGSF9,ITGB8,BMP7,BAX,CD9,ADAM15,ARVCF,SYK,GCNT1,FARP2,PVRL4,HES1,RHOA,FBLN5,RC3H2,COL7A1,FNDC3A,BCAR1,CNTNAP1,FAT4,RND3,ITGAV,FZD5,ICOSLG,L1CAM,CD33 |
| 4.532e-05 | -10.00 | protein kinase activator activity | molecular function | GO:0030295 | 53 | 16 | 16491 | 1673 |
NKX3-1,IQGAP1,CALM1,RGCC,CALM3,CDK5R1,CALM2,PRKAG2,GPRC5B,MADD,PIK3CA,CAB39,NRG1,EFNA5,ERBB3,SPRY2 |
| 4.566e-05 | -9.99 | Effects of PIP2 hydrolysis | REACTOME pathways | R-HSA-114508 | 27 | 11 | 8202 | 867 |
DGKH,ABHD12,DGKQ,ITPR1,PRKCQ,ITPR2,ITPR3,DGKG,RASGRP1,DGKE,RASGRP2 |
| 4.606e-05 | -9.99 | regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070302 | 192 | 38 | 16441 | 1675 |
PINK1,FOXM1,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,CTGF,IGF1R,DACT1,MAP3K9,DLG1,DUSP10,DAB2IP,MDFIC,SYK,DVL2,RASGRP1,MDFI,MAP3K3,AKT1,RIPK2,FZD4,PBK,ITCH,EZR,MAP3K6,MAPK8IP1,FZD7,ANKRD6,NOD2,MAP3K5,FZD5,F2RL1,GAB1,HIPK3,XDH |
| 4.642e-05 | -9.98 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | 197 | 38 | 17758 | 1761 |
SUN1,CD99,AASS,DAP,TP53,ERBB2,BCL2L1,VASH1,SEPP1,PDIA4,RABGGTA,TMEM63A,CDK16,SH3BP1,TBCD,CD9,LGMN,PTPRE,SMYD5,CTDSP2,RHOA,TESK1,UTRN,CR2,RNF113A,C15orf39,IDH1,MDK,ALDH3B1,INPP4B,NRG1,IRF7,ZMIZ1,ARSB,LTA4H,LIFR,L1CAM,CD33 |
| 4.701e-05 | -9.97 | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | 190 | 37 | 17758 | 1761 |
ARHGAP11A,CASP3,GNPDA1,CKAP2,SLC25A13,CDCA8,LACTB2,BARD1,PHLDA1,HLA-A,RRBP1,RANBP1,MDFIC,ALDH7A1,MANF,TIAM1,SEPHS1,PLK1,PLSCR1,FIGNL1,PBK,CDC20,MBNL3,LITAF,CCDC34,DUSP4,SAV1,PRIM1,FRMD4B,ZNF367,CDCA5,PGRMC1,GEM,CCNB2,E2F8,MELK,ACOT7 |
| 4.701e-05 | -9.97 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | 190 | 37 | 17758 | 1761 |
MAN2B2,LMTK3,VASH1,CYP26A1,PDGFA,CPNE2,CA2,FAM46A,VASN,OSBPL3,FUT8,PPP4R1,C10orf54,EPB41L4B,SYTL3,MED30,GPR161,FAH,DLGAP1,CPD,ELK3,NR4A1,CORO2A,MPP1,PTGER4,MBNL3,PRICKLE1,DUSP4,ALCAM,GALNT3,SLC6A6,KCNMB4,FAM83D,NFKBIZ,SERPINB1,NRBP1,MYL12B |
| 4.709e-05 | -9.96 | Rab_BD | interpro domains | IPR010911 | 12 | 7 | 18293 | 1814 |
EXPH5,SYTL4,MLPH,MYRIP,SYTL3,RIMS2,SYTL2 |
| 4.741e-05 | -9.96 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | 169 | 34 | 17758 | 1761 |
MAN2B2,DNAJC3,ITGA6,EPHA4,TMX4,HABP4,PDCL,SELL,ASAH1,SNN,TRIB2,FAM46C,MECOM,MARCH8,OTUD1,SORL1,SGK1,PIM1,MARCH2,CITED2,ZRANB1,PRKCQ,FOS,RASGRP2,IRS2,SCARB2,PTPRJ,COQ10A,PELI2,YOD1,NFKBIZ,NR4A2,EPB41L4A,MAP3K5 |
| 4.741e-05 | -9.96 | protein serine/threonine kinase inhibitor activity | molecular function | GO:0030291 | 28 | 11 | 16491 | 1673 |
CDKN2C,CASP3,SPRED1,PRKAG2,CDKN1C,CDKN1B,PRKAR2B,HSPB1,CDKN2D,SPRY2,PKIA |
| 4.855e-05 | -9.93 | lysosomal lumen | cellular component | GO:0043202 | 83 | 21 | 17570 | 1756 |
LAMP2,GAA,HSPG2,GUSB,HEXB,SDC4,ASAH1,SDC1,ATP13A2,FUCA1,CTSL,GNS,SCARB2,HPSE,CTSV,GALNS,CTSA,GLA,LGMN,ARSB,GM2A |
| 4.860e-05 | -9.93 | WIELAND_UP_BY_HBV_INFECTION | MSigDB lists | WIELAND_UP_BY_HBV_INFECTION | 96 | 23 | 17758 | 1761 |
PARP12,LGALS3,PSME2,HLA-E,PBK,HLA-F,PTTG1,PSME1,ARHGDIB,DENND2D,HLA-A,CD83,HLA-B,TAPBP,CTSC,DRAM1,AURKA,RAB20,RFX5,HLA-C,PIK3CD,UBE2C,GM2A |
| 4.864e-05 | -9.93 | renal system development | biological process | GO:0072001 | 271 | 49 | 16441 | 1675 |
NKX3-1,CDKN1C,LGR4,THRA,IQGAP1,ITGA6,LRP4,RET,EPHA4,SOX9,SDC4,TGFBR1,OSR2,SDC1,PDGFB,SIX4,SGPL1,MECOM,CTNNBIP1,EPCAM,CA2,ITGA3,NPNT,BMP7,FRAS1,DLG1,TFAP2A,BAX,AKR1B1,TACSTD2,NOTCH3,TIPARP,SULF2,GCNT1,HES1,FMN1,AMER1,PYGO1,NPHP3,FAT4,FGFR2,WFS1,TBX18,OVOL1,GDF11,SOX8,OSR1,PCSK5,ADAMTS16 |
| 4.917e-05 | -9.92 | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | MSigDB lists | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | 417 | 67 | 17758 | 1761 |
ARHGAP11A,CCNE2,UGT8,FOXM1,GNPDA1,CCNB1,HDAC6,BARD1,ERP29,STIL,MNS1,WEE1,IMPAD1,KIF14,PASK,PLK4,RTKN2,ESPN,HYLS1,LRP11,TMEM200B,PLK1,CENPA,FIGNL1,SYNE2,NUSAP1,CDCA2,PKMYT1,CCNF,LHFPL2,ADRBK2,ARHGEF26,MSL1,DNM1L,TSPAN18,MLKL,REEP4,RAP1GAP,NRGN,DENND5B,GPSM2,FAM81A,PSIP1,PARM1,PRRG4,M6PR,WWP2,RAVER2,LYPD6,PPP4R1,ADCK2,NEK2,TAGLN2,FAR2,CNPY3,MPHOSPH9,MED22,SUN2,SHMT1,MYBL2,KIF11,BORA,C3orf58,AURKA,CENPE,HOOK1,MELK |
| 4.954e-05 | -9.91 | liver | COSMIC cancer mutations | liver | 16979 | 1709 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,CMTM6,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,MEGF8,ATP5H,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,GNA11,PSMA4,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,COX20,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,TBCD,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,NUP62CL,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,S100A4,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,SPC25,IL15,PSME2,MORC4,TDRKH,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.013e-05 | -9.90 | ZHANG_PROLIFERATING_VS_QUIESCENT | MSigDB lists | ZHANG_PROLIFERATING_VS_QUIESCENT | 49 | 15 | 17758 | 1761 |
GNAS,CCND1,CASP3,RHOA,CTGF,PLAUR,AXL,ITGA6,BAX,IGFBP2,ITGAV,CCNB1,GSTP1,HSPB1,CASP4 |
| 5.016e-05 | -9.90 | FERM/acyl-CoA-bd_prot_3-hlx | interpro domains | IPR014352 | 49 | 15 | 18293 | 1814 |
EPB41L5,ACBD5,PLEKHH2,FRMD4A,NF2,FRMD6,DBI,ECI2,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 5.022e-05 | -9.90 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 378 | 62 | 17758 | 1761 |
GRN,LMO7,CD99,GAA,PCOLCE,MRC2,SERPINE2,GNPDA1,HEBP1,DAP,THRA,DNAJB2,AES,COL4A5,ITPR2,NUCB2,FAM21C,SIX4,KIAA1161,GNS,RCN1,APLP2,PTEN,IL6ST,COL6A1,AIM1,SLC44A2,BRI3,TWIST1,KLF9,F2R,SGCB,SLC12A2,S100A13,NAGA,CTDSP2,RBMS2,CYP1B1,LAMP2,SEC23A,SMARCA2,COL6A2,CAPN6,IFITM3,CASP9,PIK3R1,NPC2,IDH1,TP53INP2,SESN1,NFIB,CYB5A,NFIX,PIAS3,TAPBP,TIMP3,FGFR2,MATN2,CTSA,NDFIP1,MYL12B,XDH |
| 5.028e-05 | -9.90 | positive regulation of protein modification process | biological process | GO:0031401 | 1170 | 160 | 16441 | 1675 |
TXN,CAMKK1,EPHA4,ARFGEF1,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,FANCI,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PIK3CA,DLG1,SLC39A10,RASGRP1,PLK1,PRKAR2B,CDK1,PIAS3,PLCG1,GPRC5B,ANKRD6,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,DNAJB2,RASA2,SOX9,CALM3,TEC,IGF1R,CYR61,MAP3K9,MDFIC,PIM1,MYDGF,NCAM1,WNT3A,CCDC88A,MDFI,MMD,CALM1,PDE5A,STRADB,PSMA4,CDK5R1,RASA1,FAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,ST5,KIF14,BCL6,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,CHP1,MAP3K3,SIRT1,TIMP2,AKT1,RIPK2,FZD4,CDC20,CDCA2,CD40,MAP3K6,FZD7,IRS2,PPP2R5A,JAK1,STK26,WFS1,SLC27A1,NRG1,SPTBN5,EFNA5,NKX3-1,PINK1,SDC4,PSMD10,GDF15,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,PRICKLE1,YES1,GPLD1,BANK1,ACVRL1,FGFR2,RAP2C,NMI,RYK,ARRB1,PPP2R3C,GRIN2D,LRRK1,CENPE,GPER1,FZD5,NDFIP1,UBE2C,JARID2 |
| 5.081e-05 | -9.89 | MODULE_321 | MSigDB lists | MODULE_321 | 109 | 25 | 17758 | 1761 |
LTBP1,SEC23A,GCLM,DEPDC1,ACO1,COL18A1,GSTP1,PHLDA1,CASP4,NRP2,FAS,BTG3,APLP2,ITGA3,CTSC,TWSG1,CORO1C,CLIP4,ALDH7A1,NRG1,ITGAV,LRP11,NRGN,PTPRE,CKAP4 |
| 5.098e-05 | -9.88 | V$OCT1_05 | MSigDB lists | V$OCT1_05 | 234 | 43 | 17758 | 1761 |
THRA,MRAS,HOXB2,PPP2R3A,SLC9A7,NRP2,SCML1,TFAP4,FOXP2,SCNN1A,ADORA1,PTEN,RGS3,LHX6,CNNM4,TSPAN13,MANF,PIM1,PDE4D,DGKG,ARAP2,ING1,PLEKHA6,ELK3,FZD4,ITCH,SERTAD4,STAT4,LDB2,ITPR3,FOS,COL12A1,NIN,DPYSL3,ENPP1,ALDH5A1,GPRC5B,FGFR2,NR4A3,TMOD2,SP6,CEP41,TLL2 |
| 5.109e-05 | -9.88 | positive regulation of cell death | biological process | GO:0010942 | 596 | 91 | 16441 | 1675 |
CASP3,NQO1,INPP5D,RET,TP53,COL18A1,BCL2L1,CAMK1D,HDAC6,AIFM2,BARD1,PHLDA1,BCAP31,ARHGEF16,RPS6KA2,CTGF,SIVA1,ALDH1A3,BCL6,CDKN1B,DAB2IP,EGLN3,TIAM1,F2R,CYP1B1,SIRT1,PPIF,RIPK2,AKT1,ACVR1C,CASP9,SLC11A2,CD40,PRKRA,SAV1,STK17B,ABR,DNM1L,CDK19,NGFRAP1,KLF11,FGD1,BIN1,ARHGEF3,PINK1,BMF,NKX3-1,ARHGEF11,DAP,ITGA6,PDIA3,TGFBR1,AES,ADAMTSL4,TOP2A,TFAP4,CARD8,CYR61,CTSC,PTEN,BMP7,TFAP2A,BAX,MAP3K9,DAPK1,PLEKHF1,BUB1,TNFRSF12A,WNT3A,OSGIN1,RHOA,RAPGEF2,PLAUR,ANO6,GRIN1,RGCC,SCRIB,ELK1,CDK5R1,FAS,GPLD1,STK17A,NR4A3,ARRB1,GPER1,MAP3K5,ARHGEF9,RARG,MELK,ARHGEF4,XDH |
| 5.169e-05 | -9.87 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 66 | 18 | 17758 | 1761 |
GFPT1,CASP3,SORT1,TIMP2,AVPI1,NR4A1,F12,DNAJB9,PDIA4,APOBEC3B,AGPAT2,UAP1,ZFP36,UBE2J1,TNFRSF12A,ITPKA,HSPB1,TRAM1 |
| 5.169e-05 | -9.87 | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MSigDB lists | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 66 | 18 | 17758 | 1761 |
PVRL4,GCA,COL9A3,CD55,ATP8A1,FAS,MMP15,ARHGAP24,PITX2,PRKG1,DAPK1,DIXDC1,IGFBP2,ESPN,NOTCH3,SLC27A3,ABCA1,HOXC13 |
| 5.174e-05 | -9.87 | RhoGEF | smart domains | SM00325 | 66 | 19 | 9131 | 997 |
RASGRF1,ARHGEF28,ARHGEF3,ARHGEF11,SPATA13,ARHGEF16,ABR,ARHGEF26,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,PLEKHG1,FGD6,TIAM1,ARHGEF9,ARHGEF4,FGD1,FARP2 |
| 5.176e-05 | -9.87 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 2342 | 293 | 16441 | 1675 |
TXN,PPP4R4,LGR4,TSC22D3,DNAJC3,PSME1,MORF4L2,CCNB1,BARD1,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,RGS3,FOSB,IRF2,CRY2,ZBTB18,TIPARP,APOBEC3G,SMARCA2,TNIP1,PBK,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,POR,AHRR,PIAS3,ENPP1,LIMK1,TRAF3IP1,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,HSPB1,F2RL1,E2F8,CDKN1C,SOX9,RAB23,MECOM,ELF3,MARCH8,TFAP4,PAIP2B,BHLHE41,DAPK1,SORL1,NUP85,SOCS5,SALL4,CALM1,EPHA1,PSMA4,NFIB,FAS,AP1AR,PRKAG2,ETS2,SEMA4D,SFMBT1,NR4A2,STK39,PER3,SERPINB1,NUP58,XDH,EGLN1,SPRED1,S100A11,THRA,INPP5D,RPS6KA1,CAST,PTTG1,CCND1,APLP2,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,CDKN2D,MYT1,NR2C1,CAMSAP3,APOBEC3D,DRAP1,RAD17,PKMYT1,H2AFV,SNX12,NFIX,WFS1,CORO1C,KLF5,NRG1,RGS14,CBX7,TNRC6C,NKX3-1,DEPDC1,APOBEC3H,PKN1,GSTP1,FGF19,TIPRL,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,ITGB8,RNF128,PTEN,CST3,BAX,ATP8B1,TMBIM6,WWP1,CITED2,CNOT6L,SPRY2,TRIM62,NCOA2,CRTAP,TGIF1,FURIN,CDK5RAP1,PITX2,TIMP3,FGFR2,NR1D2,ACVRL1,TBX18,NR4A3,ITGAV,GPER1,LRRK1,HMGA1,OSR1,CPEB2,JARID2,SIGIRR,CASP3,CRYM,CNOT8,LMCD1,NDRG2,HDAC6,ERP29,PDGFB,SIVA1,PASK,MITF,DLG1,DUSP10,MYBL1,CYP1B1,PLK1,THRB,CD55,KCNIP3,TRIM8,ITCH,CBX6,EZR,PRKRA,OPTN,NEIL1,KLF12,KLF11,LMTK3,RUNX2,SERPINE2,UBASH3B,DNAJB2,PDCL,CALM3,HES2,FBLN1,IGF1R,GATA2,MDFIC,PIM1,RFX5,ETV7,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,CDK5R1,NUDT16,PLPP3,NFKBIA,NLRC5,YOD1,JAK3,IFI6,RARG,TOB1,GAS2L1,NF2,FOXM1,PSME2,CTDSPL,TP53,TDRKH,OSR2,SYTL2,SVBP,SETDB2,BCL6,TWIST1,NOTCH3,CTDSP2,CHP1,SIRT1,ERLEC1,TIMP2,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,SOCS3,ARHGAP35,DNAJC10,IDE,PTPRJ,RBL1,STK38,PEX2,OVOL1,PTBP3,TLE1,IRF7,ARFGEF3,GLIS3,PINK1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,SH2D4A,FZD6,HDAC9,CD109,IRF2BPL,FOXP2,TAF1B,BMP7,UBE2J1,TFAP2A,TRIM21,BUB1,IQGAP3,NFE2L3,HES1,PSMB4,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,COL7A1,RUNX3,BBS2,MAPK8IP1,SWAP70,BANK1,SERPINA1,NMI,SPINT2,ARRB1,SOX8,UBE2C,NDFIP1,HIPK3,AHR,PKIA,ZBTB33 |
| 5.213e-05 | -9.86 | ERBB4 (erb-b2 receptor tyrosine kinase 4) | protein interactions | 2066 | 56 | 17 | 16036 | 1726 |
SNTB2,ITCH,TP53,NRG2,ERBB2,HDAC6,RASA1,PIAS3,CTGF,ANKS1B,LRIG1,DLG1,NRG1,WWP1,ERBB3,DLG3,SYK |
| 5.230e-05 | -9.86 | Ser/Thr_kinase_AS | interpro domains | IPR008271 | 309 | 53 | 18293 | 1814 |
PRKAA2,PINK1,CDK17,NUAK1,CIT,CAMKK1,RPS6KA1,TGFBR1,GRK6,CAMK1D,PKN1,PRKACA,BMP2K,DAPK2,WEE1,RPS6KA2,ADRBK1,CDK16,PASK,SGK3,PRKG1,MAP3K9,NEK2,DAPK1,SGK1,BUB1,PIM1,MAST4,PLK1,AKT1,RIPK2,ACVR1C,PBK,EIF2AK1,PRKCQ,PKMYT1,PDIK1L,MAP3K6,CDK1,ADRBK2,STK17B,STK17A,MAPKAPK2,CDK19,ACVRL1,STK38,CSNK1G1,PLK2,AURKA,CDK18,MAP3K5,HIPK3,MELK |
| 5.270e-05 | -9.85 | tube closure | biological process | GO:0060606 | 88 | 22 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 5.281e-05 | -9.85 | breast-carcinoma | COSMIC cancer mutations | breast-carcinoma | 15843 | 1613 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,LACTB2,DPP8,FAM46C,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,CLMN,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,GRK6,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,COX20,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,ILDR1,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,S100A2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,TRIOBP,ZNF704,SLC27A3,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,E2F7,TMEM87B,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,HSF2,METTL7A,ARHGEF37,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,ITCH,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,CCNE2,LMO7,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,IL18,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,ECI2,NKAPP1,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,TRIM2,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,NKRF,DSE,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,SLC1A3,BMP2K,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNPY3,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,HEBP1,CPT2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,PROM2,KLF7,GAS2L1,FAM92A1,IL15,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,PDIA6,F2R,SCYL3,FRS3,MAP3K3,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 5.283e-05 | -9.85 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | 191 | 37 | 17758 | 1761 |
DDX58,ARHGAP11A,NCKAP5,ILDR1,EPAS1,AK7,SDC4,KCTD12,TRMT2B,FAM46C,HMGXB4,SYTL2,IL17RB,APOBEC3B,FAM111A,UBE2Q2,OSBPL3,NEK2,PLEKHF1,NAGA,GCNT1,HMMR,FZD4,CORO2A,RAD17,IFIT3,CMTM7,OPTN,ANKRD6,NR4A3,SPCS3,TMEM159,GLCCI1,NDFIP1,CBX7,AHR,XDH |
| 5.283e-05 | -9.85 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 191 | 37 | 17758 | 1761 |
GRN,SORT1,RUNX2,CD63,HEXB,EFHD2,NDRG2,KCTD12,IL13RA1,IL18,MGST2,GSTP1,SIRPA,LMNA,DPYSL2,CST3,DAPK1,PTPRE,PLCB2,TIPARP,NAGA,PPIF,PGM1,ALDH2,MCTP1,S100A4,ATP1B1,DOCK5,SLC25A5,STX3,ETS2,SH3BP4,ARRB1,NDFIP1,TOB1,AHR,CD33 |
| 5.283e-05 | -9.85 | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | 191 | 37 | 17758 | 1761 |
GRN,PARP12,S100A11,CALM3,HERC5,HERC6,CENPN,LGALS3BP,H1FX,CALM2,BTG3,OAS3,S100A6,LAMP3,REC8,MX1,PLSCR1,IFITM3,MICB,USP18,SAT1,CALM1,UBE2A,FNDC3A,SPTLC2,RHEB,ARF4,FAS,HPSE,C19orf66,H1F0,PVRL2,CDCA5,IRF7,CMPK2,PLIN3,IFI6 |
| 5.296e-05 | -9.85 | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 294 | 51 | 17758 | 1761 |
PLA2G4A,ZMAT1,CTHRC1,GOLIM4,RUNX2,FAM92A1,FRMD6,ATP9A,SLC25A27,IL18,ISYNA1,PM20D2,SEPP1,C11orf95,BEX2,RAVER2,PLS3,RCN1,CD109,TNS3,SPIN4,GATA2,DAPK1,LIMCH1,SLC39A10,FAIM,F2R,BTBD3,MAST4,SCN3A,ABCC1,WBP5,SYPL1,PDGFC,SMARCA2,SLC39A8,GALNT7,ZNF618,FRMD4B,PRDX4,DPYSL3,HLF,ANKRD6,HOXA9,TCEAL4,PPM1H,SH3BP4,ZNF165,FHL1,F2RL1,HSPB1 |
| 5.322e-05 | -9.84 | KOYAMA_SEMA3B_TARGETS_UP | MSigDB lists | KOYAMA_SEMA3B_TARGETS_UP | 264 | 47 | 17758 | 1761 |
CTHRC1,IGFBP6,PKP2,GDF15,CRABP2,LGALS3BP,SIRPA,PDGFA,NOV,CTGF,SP100,RNF128,PTEN,CTSC,KCNN4,PAQR5,FRAS1,TOX2,AIM1,AOX1,ARVCF,ACOX2,MINPP1,DLG3,WBP5,SEMA3B,SUN2,PCGF5,PLAUR,SH3BGRL,CASP9,HTATIP2,ARHGDIB,ITPR3,ANTXR1,TCEAL8,ZNF618,STEAP1,SWAP70,SERPINA1,PVRL2,AXL,PLEKHG1,SERPINI1,LTBP2,FBXO27,SLC27A3 |
| 5.336e-05 | -9.84 | IL-4 signaling Pathway | WikiPathways | WP395 | 63 | 19 | 4455 | 516 |
AKT1,INPP5D,PIK3R1,IL13RA1,BCL2L1,ELK1,ETS1,ADRBK2,RASA1,SOCS3,IRS2,PLCG1,JAK1,PIK3CA,MAPK11,HMGA1,PIK3CD,JAK3,SOCS5 |
| 5.340e-05 | -9.84 | regulation of cell projection organization | biological process | GO:0031344 | 509 | 80 | 16441 | 1675 |
FOXO6,SSH1,EPHA4,RET,PLXNA1,CAMK1D,MNS1,EPS8L2,NCS1,DPYSL2,DAB2IP,ESPN,TACSTD2,SEMA3G,CTTN,PACSIN1,TIAM1,SEMA3B,SSH3,AKT1,CDC20,EZR,KLK6,PRKCQ,ARHGAP35,DPYSL3,GPRC5B,BHLHB9,PLK2,CORO1C,PTK7,LIMK1,SIPA1L1,FAM110C,KLF5,EFNA5,NRG1,ITPKA,ARF6,RAP1GAP,F2RL1,LZTS1,COBL,GRN,SEMA6B,PIFO,SERPINE2,TBC1D1,CIT,LRP4,TGFBR1,NCKAP1,CRABP2,ITGA3,PTEN,MEGF8,BMP7,KIF13B,KIAA0319,ATP8B1,TNFRSF12A,WNT3A,SPRY2,RIMS2,CCDC88A,RHOA,RAPGEF2,GRIN1,CDK5R1,ARHGAP24,PTPRF,SEMA4D,TMEM30A,PLD1,ARPC2,ARSB,SEMA3A,L1CAM,PROM2,ADAMTS16 |
| 5.345e-05 | -9.84 | KEGG_CELL_ADHESION_MOLECULES_CAMS | MSigDB lists | KEGG_CELL_ADHESION_MOLECULES_CAMS | 129 | 28 | 17758 | 1761 |
CD99,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,CD40,SDC1,ALCAM,HLA-A,NEO1,PTPRF,CNTNAP1,HLA-B,CDH1,ITGB8,PVRL2,CDH3,CLDN4,HLA-C,ITGAV,ICOSLG,NCAM1,L1CAM,OCLN |
| 5.371e-05 | -9.83 | YAMAZAKI_TCEB3_TARGETS_UP | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_UP | 170 | 34 | 17758 | 1761 |
HSPG2,EPAS1,PDIA3,COL4A5,CTSZ,CYP26A1,GNS,RCN1,SUSD2,UBE2Q2,CYR61,FLRT3,RRBP1,FUT8,CST3,MDFIC,EPHB4,LGMN,CITED2,AMOTL2,SGCE,NR4A1,PTPN9,AMFR,SAT1,FURIN,ATP1B1,FNDC3A,ARF4,GNAS,TIMP3,PLOD2,P4HA2,DOCK9 |
| 5.573e-05 | -9.79 | MODULE_118 | MSigDB lists | MODULE_118 | 395 | 64 | 17758 | 1761 |
DLGAP5,HSPG2,NQO1,S100A11,FOXM1,PTTG1,NDC80,C5orf30,NRG2,CCNB1,CARD10,CHPF,IER3,DAPK2,EPCAM,CDKN2C,KIF14,IFIT1,BTBD3,CKS2,CYP1B1,PLK1,SGCE,CENPA,S100A4,CDC20,ARHGDIB,LOXL2,PKMYT1,CCNF,ALCAM,CDK1,DPYSL3,MDK,MAFF,ABCA1,GRN,ENO2,ITGA6,GDF15,M6PR,TOP2A,ITGA3,CTSC,CYR61,CALD1,KCNN4,ALDH7A1,IGFBP2,IGSF3,HMMR,FADS2,ZWINT,PRSS23,MYBL2,GGH,FOS,KIF11,TIMP3,PLOD2,RND3,CCNB2,UBE2C,CD33 |
| 5.635e-05 | -9.78 | FERM_N | interpro domains | IPR018979 | 29 | 11 | 18293 | 1814 |
EPB41L5,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 5.687e-05 | -9.77 | PID_FGF_PATHWAY | MSigDB lists | PID_FGF_PATHWAY | 55 | 16 | 17758 | 1761 |
RUNX2,SSH1,AKT1,PLAUR,RPS6KA1,PIK3R1,FOS,FGF19,PLCG1,CDH1,FGFR2,PIK3CA,CTTN,NCAM1,GAB1,SPRY2 |
| 5.707e-05 | -9.77 | FINETTI_BREAST_CANCER_KINOME_RED | MSigDB lists | FINETTI_BREAST_CANCER_KINOME_RED | 16 | 8 | 17758 | 1761 |
PLK1,PBK,NEK2,PLK4,AURKA,BUB1,CDK1,MELK |
| 5.740e-05 | -9.77 | regulation of biological process | biological process | GO:0050789 | 10636 | 1155 | 16441 | 1675 |
HECA,HEXB,RET,CARD10,LTBP3,GRM5,ZNF275,CDKN2C,CLDN4,CRY2,TMEM37,TIAM1,TIPARP,CDA,TFAP2C,PRKAR2B,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,RAB23,GPSM2,FAM21C,HPCAL4,MARCH8,TFAP4,PAIP2B,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,ALPK1,MYDGF,DGKG,MYLIP,NUP85,PPP6R1,PAQR7,PYM1,ERO1A,ELK1,NPHP3,GNA11,PSMA4,PLIN5,ETS2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,INPP5D,CD82,PTTG1,GRK6,MGST2,MVB12B,ST5,CDH1,SH3BP1,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,SAT1,HTATIP2,GTF2A2,SNX12,ZNF618,NFIX,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,TCAF1,CKAP2,ESRP1,SDC4,HABP4,BTN3A1,CTSZ,PLPPR4,BEX2,SGPL1,CTNNBIP1,DIRAS3,ITGB8,IGSF9,FAM20B,CST3,BAX,IGFBP2,MED22,PARP9,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,CNTNAP1,SYT7,DBI,NR4A3,ITGAV,OSR1,TMEM131,CCNI,ILDR1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,NPNT,IL6ST,MITF,PASK,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,RINL,KIF13B,TBCD,SELK,PIM1,WNT3A,DPYSL5,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,FOXD2,RASGRP2,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,LMO4,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,PTPRJ,IDE,RBL1,MMP17,STK38,EFNA5,IRF7,SYT13,ARFGEF3,BIN1,ZMAT1,PINK1,CPEB4,CDCA8,GTF3A,GDF15,HMGN3,AIP,PARM1,DNAJB9,SH2D4A,FZD6,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,TSPAN13,SYK,WBP5,NFE2L3,HES1,FBLN5,RHOA,PLAUR,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,PSME1,CAMK1D,VASH1,PJA2,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,SLC35C1,LDB2,POR,ANKRD10,PRDM5,BMP1,NFKBIZ,SERPINI1,F2RL1,FGD1,SEMA6B,CDKN1C,SCOC,TBC1D1,THEMIS2,TNFRSF19,TSPAN7,PSIP1,MESDC2,C9orf69,RALGPS2,BHLHE41,VASN,PPP4R1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,CALM1,NPC2,EPHA1,ANTXR1,NFIB,MMP15,AP1AR,PLEKHH2,TJP3,PELI2,FAM83D,SFMBT1,KLK7,CDK18,CABIN1,PER3,IFIH1,EHD1,SPRED1,FOXO6,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,FTH1,BCL2L1,DDR1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,PDE4D,EPHB4,TSPAN1,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,ITPR3,ALCAM,FZD7,NGFRAP1,TSPAN18,TRIOBP,CBX7,COBL,IGFBP6,DEPDC1,CENPI,EPS8,HERC5,PBX3,EFNB1,FGF19,ADGRB2,HLA-A,WWP2,SCML1,RASSF8,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,FARP2,PDGFC,TGIF1,ZWINT,ARHGEF28,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,ERAP1,LRRK1,FZD5,ESPL1,MELK,RGMA,CRYM,VARS2,SLC8B1,ERP29,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,ARHGEF37,SIVA1,TRPC1,CTTN,MYRIP,SP5,CYP1B1,NLRP4,CENPA,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,MADD,CAB39,ZNF165,SP6,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,SUCO,HLA-C,C10orf54,ZRANB1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,NUBP1,C3orf58,RANBP9,SOX13,TMEM30A,SH3BP4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,CCNE2,LMO7,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,ARTN,KIF14,REEP1,FABP6,DIXDC1,ECE1,EPB41L4B,CKS2,CHP1,PTPRU,GLO1,CD40,CASP4,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,PTBP3,SPTBN5,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,CIT,TGFBR1,TRIB2,SBF1,HMGXB4,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,MYO5A,SYBU,RC3H2,RGCC,RUNX3,TCEAL8,FOXL1,LEPR,CTSL,ARHGAP24,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,AHR,RAB3IL1,CD33,ABCG1,ACACB,IL15RA,ADD1,DNAJC3,FBXO2,CACNA2D2,NRG2,IL18,SYTL4,MORF4L2,BARD1,CA8,DAPK2,CALM2,WEE1,AP1M2,PSMD1,CABP1,ALDH1A3,KLF3,PIK3CD,SEMA3G,APOBEC3G,SMARCA2,TNIP1,SH3BGRL,LOXL2,F12,ICMT,PPP1R14C,PGF,ANKRD6,DNM1L,LIMK1,AGFG2,SERPINB6,ARF6,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,SOX9,MERTK,LMNA,ELF3,FAM13B,NEK2,NCAM1,SALL4,STAT4,MYBL2,TP53INP2,DCP2,STK17A,PTPRF,NCOA3,SEMA4D,SETD3,ITPR1,AURKA,MDH1,ARPC2,NDE1,ZNF502,SERPINB1,EGLN1,XDH,ARHGAP11A,MTM1,GRHL2,ACTR8,RGS20,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,ARHGEF40,GSTP1,ETS1,HOXB2,TIPRL,SRPX2,NEO1,PDIA4,CXCL16,CTSC,TMBIM6,ADAM15,PLEKHF1,WWP1,MAPK11,TPCN1,S100A6,CRTAP,AMOTL2,FMN1,BCL9,RAPGEF2,EIF5A2,GRIN1,NEURL1B,PITX2,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,USF2,MYL9,SIGIRR,TRIM2,CUL4B,EPHA4,NDC80,TP53I11,HDAC6,SDC1,PDGFB,SHC3,ELF5,DUSP10,MYBL1,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,EZR,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,RHEB,OPTN,DPYSL3,PLCH1,WIPI1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,ITGA7,LTBP2,ATP1B3,IFI6,RNF146,AVPI1,UPF3B,NF2,FOXM1,P3H2,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,ATP6V0B,LHX6,PLCG2,EGLN3,SCN2A,GM2A,DVL2,CTH,SIRT1,TIMP2,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PTK7,AIFM3,ZNF701,PACSIN2,MACC1,ADGRG1,CD63,DAP,PSMD10,SELL,GABRG2,NKRF,CRABP2,PPP2R3A,BUB1,KLF9,FAIM,TLE6,PSMB4,IFITM3,NR3C1,AMFR,PPARA,LITAF,PELI3,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,GAA,PPP4R4,ATP8A1,TAP1,PLXNA1,CCNB1,SLC20A1,FAM101B,CENPN,NCS1,SESN3,CTGF,ELMO2,RGS3,ZFP36,IL31RA,ATRNL1,PACSIN1,RCAN3,PBK,CASP9,NBPF3,AGO4,PIF1,SAV1,CCNF,SLC25A5,ZFAND5,ARHGEF26,AHRR,HLF,SLC25A4,PLK2,NKD1,FAM110C,SARAF,EIF4EBP2,UNC5B,TRAF5,LZTS1,DDX58,CDK17,HLA-E,DGKQ,SLC25A27,KIF23,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EPB41L5,MFI2,ZNF84,MMD,TBC1D8B,MICB,ANO6,AMER1,PIP4K2C,RASA1,STX3,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,TCEAL4,FGD6,NR4A2,MAP3K5,PLA2G4A,ARMCX3,TRIP10,S100A11,NLRX1,CAST,IQGAP1,RPS6KA1,CD274,AIFM2,MNS1,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,DAB2IP,IFIT1,LGMN,NR2C1,CAPN6,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,PPP2R5A,JAK1,STK26,SLC27A1,NRG1,KLF5,NR3C2,DENND5B,WASF3,PCOLCE,ARHGEF3,ARL4C,APOBEC3H,SPR,LGALS3BP,SIX4,TEAD3,SNTA1,FAM111A,PTEN,SGK3,SLC44A2,ATP8B1,CNOT6L,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,MPP1,FURIN,GPLD1,NUCB1,GRIN2D,GPER1,ARSB,CPEB2,JARID2,EXPH5,EMX1,CASP3,LTBP1,CAMKK1,DNER,CACNB4,DENND2D,KREMEN1,SH3KBP1,PTCHD4,NKAIN3,ARHGEF10L,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,AKR1B1,RAB20,RP2,MYH14,SLC39A10,PTPRE,RASGRP1,TRIM8,ASCL5,STRIP2,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,ADIPOR1,RAP1GAP,GRN,PIFO,LRRFIP2,PHLPP1,ZNF432,CA2,KCNN4,DIAPH2-AS1,FXYD5,RFX5,LRIF1,ALS2CL,OXR1,HMG20B,BCAR3,GNAS,FECH,ONECUT1,NUDT16,PLPP3,CGREF1,CDCA5,NFKBIA,RHOBTB2,YOD1,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,TDRKH,ARHGEF16,SS18,SVBP,SETDB2,FRYL,TWIST1,GOT1,PDIA6,F2R,FRS3,MAP3K3,ZNF525,ERBB2IP,DUSP4,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,LIFR,PPP2R2D,ANXA3,SORT1,FRMD6,LRP4,MIER3,AES,NOTUM,IL17RB,IRF2BPL,ADORA1,KIAA0319,IQGAP3,SUN2,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,MBNL3,HLA-B,PRCP,DHRS2,HOXB13,GEM,SOX8,L1CAM |
| 5.740e-05 | -9.77 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | 597 | 89 | 17758 | 1761 |
MYL9,SPC25,NF2,HOXB7,VANGL1,CTDSPL,TMX4,IL13RA1,BCL2L1,ISOC2,MGST2,PDGFB,BARD1,CARD10,CDKN2C,CCND1,ST5,CTGF,OSBPL3,PHTF1,TACSTD2,TSPAN1,ZNF365,GM2A,SEPHS1,LOC81691,USP18,SLC39A8,ARHGDIB,LOXL2,ROR1,RAB38,ICMT,CD40,CCNF,CDK1,DAG1,PRIM1,ALDH5A1,PLK2,HOXA9,NRGN,ISOC1,PPP2R2D,NUDT6,HJURP,CENPI,SOX9,EFHD2,TRMT2B,SH2D4A,SAC3D1,M6PR,TOP2A,CTNNBIP1,TNS3,MDM1,MLPH,CYR61,CTSC,CALD1,BDH1,FJX1,NEK2,OSTF1,MDFIC,BUB1,MPHOSPH9,MCCC2,MED22,AMOTL2,HES1,ARAP2,SHMT1,KIF20A,PRSS23,FBXO9,ANTXR1,CYB5A,FUCA1,ENDOD1,FAM64A,TIMM8A,DBI,PGRMC1,AGBL5,AURKA,MAP3K5,TMEM14A |
| 5.769e-05 | -9.76 | LOPEZ_MBD_TARGETS | MSigDB lists | LOPEZ_MBD_TARGETS | 900 | 125 | 17758 | 1761 |
CCNI,MTM1,SORBS1,HSPG2,EPAS1,PSME2,CPT2,RPS6KA1,THRA,HDAC11,CTDSPL,PTTG1,FBXO2,NRG2,IL27RA,LTBP3,APLP2,ATP6V0B,BTG3,ZNF75D,DOK4,RGS3,SIVA1,SERINC2,TUBG1,GOT1,CTTN,EPHB4,LGMN,PPIF,SEC61B,RIPK2,PTPRU,DRAP1,EZR,GLO1,C15orf39,TP53I3,CDK1,RHEB,ALDH3B1,CARHSP1,ALDH5A1,AGPAT2,NGFRAP1,AXL,SECTM1,BMP1,OVOL1,PIEZO1,TRAF5,MYL12B,CAPN1,CDKN1C,CD63,HLA-E,HLA-F,BLVRB,SDC4,RAB6A,HES2,NUCB2,SEPP1,GSTP1,AIP,FGF19,RABGGTA,GNS,TOP2A,DAZAP1,ADD3,IGF1R,CYR61,CTSC,CDK16,TBCD,SGK1,CD70,ABCD1,BUB1,IGFBP2,AHCY,NCAM1,SGCB,TLE6,MED22,KDELR1,FAH,TGIF1,RHOA,ELK3,PSMB4,IFITM3,GUSB,NR4A1,CORO2A,ANO6,ZNF320,LITAF,MYBL2,UBE2A,VWA1,RNF113A,NPC2,EPHA1,YES1,FNDC3A,AIF1L,RNPEP,KIF11,PSMA4,PTPRF,CNTNAP1,DCTN6,HLA-B,SCARB2,SERPINA1,SEMA4D,HNRNPH2,NFKBIA,SPINT2,ERAP1,UBE2C,CCNB2,IFI6 |
| 5.781e-05 | -9.76 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | 97 | 23 | 17758 | 1761 |
CCDC109B,MMD,EPAS1,MBNL3,FAM101B,ALCAM,GPLD1,FRMD4B,CD83,CDKN2C,SWAP70,GPRC5B,TWSG1,OSBPL3,SH3BGRL2,PIM1,CTTN,TIAM1,ALS2CL,SLC16A5,NEB,RRAGD,FAH |
| 5.781e-05 | -9.76 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 97 | 23 | 17758 | 1761 |
GAS2L1,LASP1,ZWINT,NQO1,EPS8,RGS20,ARHGDIB,HMGN3,GALNT7,ISOC2,ALCAM,FBLN1,ATP10D,PLS3,TNS3,DPYSL2,CALD1,AIM1,ATP1B3,ZMIZ1,SPRY2,TOB1,RUSC1 |
| 5.809e-05 | -9.75 | response to peptide | biological process | GO:1901652 | 590 | 90 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,PSME2,NRG2,ERBB2,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,SESN3,PSMD1,CTGF,SHC3,KLF3,PIK3CA,AKR1B1,CDKN1B,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,RIPK2,AKT1,ACVR1C,PRKCQ,PRKAR2B,ERBB2IP,POR,CASP4,DAG1,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,NOD2,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,GAB1,RRAGD,PRKAA2,SORT1,RASA2,CALM3,PSMD10,FGF19,HDAC9,IGF1R,BMP7,ERBB3,NCAM1,MYO5A,GCNT1,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,NFKBIA,NR4A3,GRIN2D,NR4A2,GPER1,JAK3,TBC1D4,CPEB2 |
| 5.848e-05 | -9.75 | V$FOXO1_02 | MSigDB lists | V$FOXO1_02 | 228 | 42 | 17758 | 1761 |
CDKN1C,CHCHD7,THRA,TSC22D3,ETV5,SEPP1,DHRS3,SH2D4A,TFAP4,PDGFA,CD109,FOXP2,ST5,FRY,ITGB8,IL6ST,LMO4,MITF,DIXDC1,TSPAN13,KLF9,CLIP2,TRIM8,KIF20A,SERTAD4,NUB1,TCF7,ROR1,NFIB,NFIX,GNAS,MDK,PITX2,KLF12,PELI2,NRG1,EIF4EBP2,LEMD1,C1orf43,LIFR,MAFF,EHD1 |
| 5.930e-05 | -9.73 | GSE27786_LSK_VS_LIN_NEG_CELL_UP | MSigDB lists | GSE27786_LSK_VS_LIN_NEG_CELL_UP | 192 | 37 | 17758 | 1761 |
MFSD3,NFKBIE,KCTD12,HMGN3,HDAC6,CCND1,KIAA1107,PIK3AP1,ELMO2,SLC44A2,BRI3,OAS3,PLCB2,DGKG,CTDSP2,CRTAP,SGCE,CAMSAP3,AKT1,ADCK3,LRRC66,ZFAND5,DAG1,SPNS3,MUM1L1,FOXD2,CMTM7,NUDT16,AGPAT2,H1F0,HOXA9,ERAP1,VSIG10,TMEM159,TANC2,NRBP1,TMEM173 |
| 5.965e-05 | -9.73 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | 110 | 25 | 17758 | 1761 |
MAP3K3,GRN,LAMP2,SLC2A4,GOLIM4,ADD1,FIGNL1,FOXJ2,AES,COL7A1,RNF113A,DENND2D,NRP2,FECH,PTPRF,ADD3,NR1D2,PHTF1,FUT8,ANKRD12,ADAM15,WWP1,DGKG,NRBP1,SMAGP |
| 5.989e-05 | -9.72 | Collagen formation | REACTOME pathways | R-HSA-1474290 | 86 | 22 | 8202 | 867 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,P3H2,ITGA6,COL18A1,COL4A5,COL7A1,LOXL2,COL12A1,CTSL,COL13A1,PLOD2,CTSV,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 6.007e-05 | -9.72 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 185 | 36 | 17758 | 1761 |
GCLM,SLC35D2,TXN,IL15RA,LGALS3,S100A11,CD63,CAST,IQGAP1,TMX4,PTTG1,EFHD2,BTG3,TYMP,CTSC,RGS3,OSBPL3,MDFIC,TMEM64,FAR2,PDIA6,MYBL1,PPIF,C6orf1,S100A4,ALCAM,FRMD4B,FAS,NOD2,NETO2,CTSA,EIF4EBP2,PIEZO1,MAP3K5,AHR,CPPED1 |
| 6.030e-05 | -9.72 | V$NGFIC_01 | MSigDB lists | V$NGFIC_01 | 243 | 44 | 17758 | 1761 |
LASP1,CDK17,CEP70,HOXB7,UBASH3B,TP53I11,PDGFB,SPTB,SH3KBP1,HDAC9,CDKN2C,TFAP4,APLP2,RALGPS2,ZCCHC12,SH3BP1,WDR44,KLF3,RRBP1,BCL6,KCNS3,CNNM4,TNFRSF12A,CRY2,ERBB3,CNOT6L,RASGEF1A,SMYD5,C9orf72,DVL2,SUN2,ATL1,NFE2L1,RGAG1,GRIN1,SLC25A5,MAN2A2,PITX2,CORO1C,MADD,PITPNA,MAP3K5,PLOD3,NRGN |
| 6.036e-05 | -9.72 | CHYLA_CBFA2T3_TARGETS_DN | MSigDB lists | CHYLA_CBFA2T3_TARGETS_DN | 221 | 41 | 17758 | 1761 |
BCAM,TRIM2,SORBS1,NQO1,TSPAN15,HEBP1,CD82,BLVRB,FHDC1,LMCD1,PM20D2,GPSM2,AIFM2,LMNA,SH2D4A,PARM1,EPDR1,MARCH8,RNF128,BDH1,NTN4,TINAGL1,IGSF3,TRAK2,REC8,SLC39A8,CXorf57,KIF1C,SLC11A2,TNS1,C2orf69,FZD7,CARHSP1,ATP7B,P4HA2,RYK,DHTKD1,KLF5,IRF7,RAB3IL1,NIPA1 |
| 6.080e-05 | -9.71 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | MSigDB lists | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | 91 | 22 | 17758 | 1761 |
AKT1,NR4A1,CALM1,CASP9,PIK3R1,CALM3,PRKAR2B,ITPR2,ITPR3,PHLPP1,PRKACA,PDGFB,BCAR1,CDK1,RASA1,CALM2,PDGFA,PLCG1,ADRBK1,PTEN,PIK3CA,CDKN1B |
| 6.081e-05 | -9.71 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | 9 | 6 | 17758 | 1761 |
NR4A2,NFKBIZ,EGLN3,FOS,NR4A1,PTGER4 |
| 6.198e-05 | -9.69 | Ras protein signal transduction | biological process | GO:0007265 | 394 | 65 | 16441 | 1675 |
SPRED1,PSME2,TP53,ERBB2,NRG2,PSME1,MRAS,PDGFB,SPTB,EPS8L2,PDGFA,CALM2,RAB15,PSMD1,SHC3,BCL6,DAB2IP,RAB20,RASGEF1A,RAB27B,TIAM1,RASGRP1,FRS3,ARHGDIB,RAB38,IRS2,JAK1,LIMK1,PLK2,NRG1,SPTBN5,MAPK12,ARHGEF3,ADGRG1,ARHGEF11,RASA2,EPS8,RAB23,PSMD10,CALM3,NCKAP1,RAB6A,FGF19,MAPK11,ERBB3,IQGAP3,NCAM1,FARP2,RASGRF1,RAB3B,RHOA,PSMB4,RAPGEF2,CALM1,GRIN1,STRADB,PSMA4,RASA1,RASGRP2,MAPKAPK2,FGFR2,RAP2C,GRIN2D,PLD1,JAK3 |
| 6.206e-05 | -9.69 | TRPC3 (transient receptor potential cation channel, subfamily C, member 3) | protein interactions | 7222 | 23 | 10 | 16036 | 1726 |
MX1,PLCG1,CALM1,ITPR1,PRKG1,TRPC1,ITPR3,PLCB2,GNA11,STX3 |
| 6.268e-05 | -9.68 | apical part of cell | cellular component | GO:0045177 | 347 | 58 | 17570 | 1756 |
NF2,SLC25A27,ERBB2,GPSM2,SYTL4,VASH1,EMP2,ANO1,FZD6,EPCAM,SVBP,SCNN1A,CA2,PTEN,KCNN4,SRR,CD9,TUBG1,CLDN4,ATP8B1,IGFBP2,EPB41L4B,PDE4D,ERBB3,LGMN,RAB27B,MYRIP,SLC12A2,GM2A,DVL2,MYO5B,AMOTL2,CRB3,RAPGEF2,EZR,SLC11A2,ATP1B1,ITPR3,STX3,DUOX1,ATP1A1,TJP3,FAT4,SHROOM3,STK26,KCNK1,TMEM30A,CTSV,STK39,SPTBN5,NRG1,PLD1,MAL2,SHROOM2,MYL12B,LZTS1,OCLN,PROM2 |
| 6.276e-05 | -9.68 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1241 | 164 | 17758 | 1761 |
ADD1,HSPG2,NRG2,NDRG2,PSME1,MORF4L2,HDAC6,PDGFB,KREMEN1,SPTB,HTR1D,PLS3,DPYSL2,KLF3,NTN4,SEMA3G,ZNF462,PCGF5,SMARCA2,TRIM8,CD55,FBXL16,TNIP1,SH3BGRL,SERTAD4,NFE2L1,TMEM151A,TNS1,ARHGDIB,PRKAR2B,ZFAND5,SESN1,ABR,KLF12,HDAC1,SERPINI1,GLA,MAFF,RRAGD,LASP1,CDK17,BMF,FRMD4A,ITGA6,ETV5,RAB6A,HPCAL4,FAM13B,PIM1,CACNA1D,WNT3A,IGSF3,CYP26B1,DPYSL5,ELK3,VWA1,PDK3,EPHA1,RASA1,RASGRP2,BCAR3,PTPRF,NCOA3,COL13A1,MFSD2A,AGBL5,RHOBTB2,KLK7,ARPC2,RARG,TOB1,KLF7,SLC25A24,SLC2A4,CAST,IQGAP1,THRA,RALBP1,TP53,KCTD12,GRK6,BCAP31,KCTD9,RAD23A,NOV,SH3BP1,CDKN1B,DAB2IP,DLG3,SEMA3B,AKT1,FZD4,FOXJ2,LYRM1,KIF1C,CDCA2,MAP3K6,SNX12,SP4,FZD7,NIN,NFIX,PPP2R5A,RBL1,AXL,SLC9A6,PTK7,NRG1,KLF5,RGS14,C1orf43,REEP4,IGFBP6,ENO2,CD63,BLVRB,ARL4C,GABRG2,TGFBR1,TRIB2,EFNB1,HOXB2,TEAD3,SIX4,IRF2BPL,CD109,KIF5B,ADD3,ANKS1B,BMP7,FUT8,ATP8B1,TSPAN13,WWP1,ABCD1,SPRY2,RBMS2,WBP5,IGDCC4,NFE2L3,PVRL4,ACBD5,RHOA,NR3C1,NR4A1,DEPDC4,RUNX3,PITX2,SMTNL2,HNRNPH2,NR4A3,OTUB2,GRIN2D,SH3BGRL2,PPP2R3C,HOXB13,HMGA1,FHL1,OSR1,USF2,PTGES,AHR,PKIA,RGMA |
| 6.319e-05 | -9.67 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | 85 | 21 | 17758 | 1761 |
CD55,CPEB4,TSC22D3,FRMD6,SNTB2,ARMC7,EPHA4,BCL2L1,ATP1B1,TNFRSF19,SYTL2,TNS3,ENPP1,SHROOM3,PLEKHF1,TLE1,CDH3,KLF9,MAP3K5,SLC16A5,IGSF3 |
| 6.331e-05 | -9.67 | plasma membrane part | cellular component | GO:0044459 | 2566 | 312 | 17570 | 1756 |
LAMP1,LGR4,VANGL1,SLC25A13,RET,CACNA2D2,PLXNA1,SYTL4,PJA2,SLC20A1,NCS1,GRM5,MUC4,STIM1,CABP1,STEAP2,FUT1,KCNS3,CLDN4,TACSTD2,PACSIN1,TIAM1,SGCE,ACVR1C,SNTB2,SLC25A5,ARF4,ENPP1,SLC25A4,ATP7B,NOD2,ARF6,TRAF5,F2RL1,LZTS1,DDX58,SEMA6B,SCN5A,HLA-E,ITGA6,SLC1A3,MERTK,TSPAN7,ITGA3,ZNRF2,SNX18,LYPD3,SLC16A6,FLRT3,OPN3,SORL1,CD70,CACNA1D,NCAM1,ULBP2,SYTL3,RIMS2,GPR161,EPB41L5,FADS2,KCNJ12,MFI2,MMD,EPHA1,ANTXR1,GNA11,STX3,RASA1,FAS,PTPRF,MMP15,GABRD,SLCO4A1,SLC4A4,TJP3,SEMA4D,SLC4A3,STK39,MAL2,RUSC1,EHD1,SPRED1,SLC2A4,TCTN2,ST14,TRIP10,CD82,IQGAP1,ATP2C2,KCTD12,IL13RA1,CD274,APC2,PRKACA,DDR1,EPS8L2,SCNN1A,CDH1,CNNM4,DAB2IP,EPHB4,PDE4D,TSPAN1,DLG3,RAB27B,SCN3A,FZD4,SYNE2,CYS1,UTRN,SLC11A2,PRKCQ,ATP1B1,ITPR3,ALCAM,GABARAPL1,EPHA10,JAK1,SHROOM3,STK26,CORO1C,AXL,SIPA1L1,TSPAN18,TRABD2A,SLC27A1,NRG1,HS3ST3B1,PRIMA1,RGS14,TTC8,EPS8,SDC4,PLPPR4,EFNB1,SRPX2,HLA-A,NEO1,SNTA1,ITGB8,PTEN,ANKS1B,CD9,ATP8B1,TMBIM6,IGFBP2,ERBB3,SGCB,SPRY2,SLC16A5,S100A6,AMOTL2,PVRL4,PLSCR1,MPP1,RAPGEF2,GRIN1,YES1,AIF1L,SNTB1,CNTNAP1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,ITGAV,OCLN,CYBRD1,ESYT2,CASP3,BCAM,EPHA4,HDAC6,PDGFB,CACNB4,SDC1,TMC1,SPTB,ABCD4,HTR1D,EPCAM,NPNT,TSPAN6,IL6ST,DLG1,ABCA2,TRPC1,RP2,CTTN,MYRIP,SMAGP,KCNIP3,CD55,CR2,EZR,ROR1,EDNRA,HS6ST1,KCNMB4,KCNK1,PRKCDBP,ADIPOR1,PIEZO1,CD99,SERPINE2,LGALS3,BVES,RASA2,FXYD3,HLA-F,SLC22A31,NCKAP1,TEC,CNTNAP2,DHRS3,ANO1,CA2,IGF1R,KCNN4,TBCD,FXYD5,C10orf54,HLA-C,SLC12A2,ABCC1,PCDH1,PODXL2,RGMB,SPATA13,SCRIB,STEAP1,RASGRP2,EPN3,GNAS,SLC6A6,PVRL2,COL13A1,MFSD2A,ITGA7,PHLPP2,PLPP3,TMEM30A,PLD1,ATP1B3,SHROOM2,JAK3,PROM2,SORBS1,NF2,IL15,ERBB2,IL27RA,SLC7A2,EMP2,BCAP31,SYTL2,ECE1,SCN2A,F2R,GM2A,CLCN3,PTPRU,ERBB2IP,CD40,DAG1,ATP13A2,DUOX1,ATP1A1,PTPRJ,ABHD12,PTK7,MMP17,SPTBN5,EFNA5,SYT13,LIFR,ABCA1,BIN1,PACSIN2,ADGRG1,CD63,TSPAN15,LRP4,SELL,GABRG2,TGFBR1,FZD6,M6PR,IL17RB,ADORA1,CDK16,TSPAN13,IQGAP3,SYK,ATP2B1,DLGAP1,SYPL1,RHOA,CRB3,PLAUR,BBS2,CD83,HLA-B,CTSV,NETO2,ARRB1,GEM,L1CAM,ARHGEF4,ABCG1,CD33 |
| 6.359e-05 | -9.66 | condensed nuclear chromosome kinetochore | cellular component | GO:0000778 | 9 | 6 | 17570 | 1756 |
PLK1,REC8,BUB1,CENPA,CCNB1,NDC80 |
| 6.428e-05 | -9.65 | RABBD | prosite domains | PS50916 | 12 | 7 | 11866 | 1235 |
EXPH5,SYTL4,MLPH,MYRIP,SYTL3,RIMS2,SYTL2 |
| 6.534e-05 | -9.64 | morphogenesis of embryonic epithelium | biological process | GO:0016331 | 147 | 31 | 16441 | 1675 |
EPB41L5,TGIF1,CTHRC1,GRHL2,SALL4,ST14,SOX9,SDC4,RET,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,FGFR2,SHROOM3,PTK7,LMO4,ALDH1A3,SPINT2,TBX18,TFAP2A,TWIST1,SOX8,OSR1,RARG,COBL,DVL2 |
| 6.559e-05 | -9.63 | cytoplasmic membrane-bounded vesicle | cellular component | GO:0016023 | 1102 | 149 | 17570 | 1756 |
SUN1,LAMP1,KLK10,IL15RA,ATP8A1,HEXB,TGOLN2,SYTL4,PDGFB,ERP29,NCS1,SH3KBP1,AP1M2,STEAP2,ABCA2,RAB20,PACSIN1,MYRIP,SMAGP,LAMP3,LAMP2,SNTB2,ARHGDIB,MCFD2,OPTN,DPYSL3,TRIM9,GPRC5B,DNM1L,WIPI1,KCNK1,ATP7B,RAB11FIP1,PIK3C2B,ARF6,NRGN,PCSK5,PIFO,BMF,SERPINE2,HLA-E,HLA-F,RAB23,RAB6A,MARCH8,SNX18,RINL,ZNRF2,AHCY,CADPS2,HLA-C,WNT3A,GAD1,SYTL3,CCDC88A,CKAP4,GPR161,SNX7,KDELR1,C9orf9,KLK5,VEZT,ATP8B3,C3orf58,STX3,GNAS,EPN3,AP1AR,TMEM30A,ITPR1,SH3BP4,KLK7,ATP1B3,PLD1,TMEM173,RUSC1,PLA2G4A,SLC2A4,BCL2L1,PHLDA1,BCAP31,SYTL2,APPBP2,PDGFA,ATP6V0B,N4BP3,DAB2IP,ECE1,RAB27B,LMAN1,PDIA6,DVL2,CHP1,MYO5B,CLCN3,SEC23A,FZD4,SEPT6,RAB38,GABARAPL1,ATP1A1,STK26,SYT13,ABCA1,ARFGEF3,ANXA3,GOLIM4,PACSIN2,SORT1,CD63,PDIA3,CTSZ,PKN1,HLA-A,FZD6,PDIA4,KIF5B,CTSC,CDK16,CD9,SGK3,ADAM15,SYK,MYO5A,SYPL1,RAB3B,RAPGEF2,SYBU,GRIN1,FURIN,GGH,COL7A1,FNDC3A,RNPEP,CRISPLD2,HLA-B,NUCB1,SERPINA1,SCG2,SYT7,RAB11FIP2,FGFR2,CTSV,ARRB1,ITGAV,GPER1,FZD5,TBC1D4,OCLN |
| 6.623e-05 | -9.62 | FERM_3 | prosite domains | PS50057 | 48 | 15 | 11866 | 1235 |
FRMPD3,EPB41L5,PLEKHH2,JAK1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,JAK3,MYLIP,FARP2,FRMD4B |
| 6.649e-05 | -9.62 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | 193 | 37 | 17758 | 1761 |
DLGAP5,HJURP,FOXM1,GNPDA1,KIF23,CCNB1,FANCI,TOP2A,BDH1,PLK4,TUBG1,GOT1,FAH,LAMP3,HMMR,CENPA,SHMT1,ZWINT,KIF20A,ASPM,CDC20,NUSAP1,ICMT,KIF11,FANCE,FUCA1,SLCO4A1,CORO1C,AURKA,CSTF2,GLA,NCAPG2,UBE2C,CCNB2,ESPL1,ACOT7,MELK |
| 6.664e-05 | -9.62 | V$DR4_Q2 | MSigDB lists | V$DR4_Q2 | 244 | 44 | 17758 | 1761 |
CDK17,TM2D2,FRMD4A,GRHL2,ENO2,TGOLN2,CRABP2,PDGFB,SPTB,TEAD3,PRRG4,SCML1,NKAIN3,FOXP2,APLP2,ADD3,PIK3AP1,TOX2,MITF,DUSP10,SGK1,TNFRSF12A,ERBB3,GAD1,TLE6,TRAK2,PODXL2,LYRM1,RGAG1,STRADB,ATP1B1,TP53INP2,RASGRP2,OPTN,ARHGAP24,PGF,PTK7,NFKBIA,AMMECR1,NRG1,ABCA1,NDST3,JARID2,ABCG1 |
| 6.673e-05 | -9.61 | positive regulation of developmental process | biological process | GO:0051094 | 1108 | 152 | 16441 | 1675 |
ACACB,LGR4,EPHA4,RET,CACNA2D2,MORF4L2,CAMK1D,CCNB1,PDGFB,LTBP3,GRM5,CTGF,NPNT,IL6ST,TACSTD2,PACSIN1,TIAM1,RASGRP1,CYP1B1,ITCH,EZR,LOXL2,SAV1,POR,RHEB,DPYSL3,PLCG1,GPRC5B,HPSE,DNM1L,LIMK1,BMP1,ITPKA,HSPB1,GRN,RUNX2,SERPINE2,LGALS3,SOX9,ETV5,LMNA,MECOM,ITGA3,CA2,CYR61,GATA2,MEGF8,FLRT3,SUCO,TNFRSF12A,C10orf54,MYDGF,WNT3A,RIMS2,SOCS5,EPB41L5,MMD,ANO6,HMG20B,PDE5A,EPHA1,GNAS,NCOA3,SEMA4D,SETD3,TMEM30A,CSF1,AURKA,ARPC2,MAP3K5,SEMA3A,EHD1,FOXO6,HOXB7,NF2,IL15,THRA,INPP5D,RPS6KA1,OSR2,TNFSF9,MNS1,PDGFA,CCND1,DACT1,BCL6,DAB2IP,TWIST1,TMEM64,SIRT1,TIMP2,AKT1,RIPK2,CDC20,CD40,DAG1,SOCS3,ARHGAP35,BHLHB9,AXL,PTK7,CORO1C,TRIOBP,NRG1,EFNA5,KLF5,RGS14,COBL,MAPK12,BIN1,WASF3,CTHRC1,ANXA3,PINK1,GDF15,CRABP2,ETS1,SRPX2,TEAD3,SIX4,ADGRB2,HDAC9,NEO1,CTNNBIP1,BMP7,TFAP2A,BAX,MAPK11,IQGAP3,CITED2,SYK,TLE6,TGIF1,HES1,RHOA,RAPGEF2,ASPM,RGCC,FOS,BBS2,CD83,ACVRL1,FGFR2,TBX18,ERAP1,PPP2R3C,HMGA1,GPER1,OSR1,SOX8,ARSB,L1CAM |
| 6.712e-05 | -9.61 | blood vessel morphogenesis | biological process | GO:0048514 | 372 | 62 | 16441 | 1675 |
HSPG2,EPAS1,ADGRG1,FOXM1,COL18A1,IL18,TGFBR1,VASH1,ETS1,SRPX2,NRP2,SGPL1,PDGFA,E2F7,NOV,TYMP,CTGF,PTEN,CYR61,PIK3CA,BAX,ADAM15,DAB2IP,TNFRSF12A,EPHB4,MYDGF,NOTCH3,TIPARP,SYK,CYP1B1,SIRT1,HES1,ELK3,FZD4,NR4A1,SAT1,HTATIP2,LOXL2,EPHA1,RASA1,EDNRA,GPLD1,PGF,ARHGAP24,HS6ST1,PTPRJ,HPSE,ACVRL1,SCG2,FGFR2,PRCP,ITGA7,PNPLA6,ERAP1,EGFL7,KLF5,HOXB13,ITGAV,UNC5B,ZMIZ1,FZD5,E2F8 |
| 6.724e-05 | -9.61 | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | 7269 | 794 | 17775 | 1757 |
ACACB,KLK10,IL15RA,AASS,MRPS15,AK7,DNAJC3,RET,CACNA2D2,DHX8,NRG2,LACTB2,BARD1,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,PSMD1,SEMA3G,MANF,TMEM37,TIAM1,TIPARP,MGAT5,ERAP2,DNAAF3,NWD1,SPEF2,SMARCA2,TFAP2C,PRKAR2B,LOXL2,COL12A1,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,DNM1L,ANKRD6,ATP7B,LIMK1,FAM114A1,NOD2,AGFG2,SERPINB6,GAB1,E2F8,SCN5A,ALDH6A1,GGA1,ITGA6,SOX9,MTL5,SLC36A4,MERTK,FAM21C,TTYH3,RAVER2,RABGGTA,TFAP4,FRY,MEGF8,RIMS3,FLRT3,MAP3K9,ALPK1,PANX2,ZMYM1,NCAM1,DGKG,ULBP2,NUP85,PAQR7,HPS3,KIF20A,STAT4,MYBL2,ELK1,NPHP3,SPTLC2,SFXN5,GNA11,PTPRF,SCARB2,NCOA3,SLC4A4,ETS2,SEMA4D,ITPR1,CLMN,NDE1,ZNF502,TMEM173,XDH,DOCK9,ARHGAP11A,MTM1,TPRN,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,TNFSF9,REPS1,ZNF385B,CDS1,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,SP100,SH3BP1,DACT1,XYLT2,RTKN2,ACSL4,RASGEF1A,LRP11,ETV4,MYT1,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,COL6A2,PLEKHO1,SYNE2,HTATIP2,RAB38,DNAJB14,XRCC6BP1,NFIX,SHROOM3,CORO1C,SLC9A6,SIPA1L1,PLEKHG1,PNPLA6,RGS14,ISOC1,TTC8,TNRC6C,HABP4,OSGIN2,BTN3A1,PKN1,NUCB2,ETS1,SRPX2,PDIA4,DTX3L,DIRAS3,CXCL16,IGSF9,SLC27A6,ANKS1B,CST3,PLEKHF1,TMBIM6,IGFBP2,TPCN1,CRTAP,PARP9,AMOTL2,PVRL4,FAM160A1,RAPGEF2,PIK3R1,NUB1,EIF5A2,GRIN1,SNTB1,CNTNAP1,GALNT3,PLOD2,SYT7,ACVRL1,ITGAV,FHL1,CMPK2,DCBLD1,CYBRD1,ACOT7,BCAM,KIAA1462,EPAS1,PPM1J,CNOT8,CUL4B,FHDC1,ARFGEF1,LMCD1,NDRG2,TEX2,MGAT5B,ITPR2,HDAC6,PDGFB,SPTB,FANCI,SUSD2,CPNE2,RPS6KA2,MKRN3,IL6ST,SLC44A1,MITF,ABCA2,NTN4,ANO4,TLN2,DDX59,NEB,ZNF462,PLK1,CD55,KCNIP3,CELSR2,CR2,ANLN,IDH1,LHFPL2,ZBTB7B,DPYSL3,OPTN,KDM4D,TRIM9,MFAP3L,PLCH1,KCNMB4,WIPI1,MAP2,RAB11FIP1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRSS8,PRKAA2,RUNX2,HJURP,HLA-F,CNTNAP2,NCKAP1,IL18R1,TNS3,DAZAP1,IGF1R,SPIN4,FRAS1,FAR2,WNT3A,PLCB2,ALDH3A2,ABCC1,C9orf9,DPYSL5,CHSY3,PCDH1,PLEKHA6,RGMB,TESK1,PCBP3,MGAT4B,SPATA13,SCRIB,EIF2AK1,PDK3,ANKRD29,G2E3,CDK5R1,PRX,RASGRP2,EPN3,MAPKAPK2,H1F0,COL13A1,KBTBD2,PHLPP2,ITGA7,MFSD2A,NLRC5,LTBP2,PLD1,SEMA3A,CCNB2,USP43,AVPI1,NF2,HOXB7,XYLT1,TP53,CCDC68,ERBB2,FAM198B,LPIN3,EMP2,STIL,CYP26A1,TTC21B,WDR44,LHX6,PLCG2,SRR,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,NOTCH3,OAS3,SCN2A,CTDSP2,GM2A,DVL2,CTH,SULF2,SIRT1,MBP,AKT1,FIGNL1,PTGER4,DAG1,ATP13A2,DNAJC10,DUOX1,ATP1A1,IDE,RBL1,PTK7,STK38,ADAMTS14,IRF7,ST3GAL1,ZNF701,NDST3,MAN2B2,CMAS,COL9A3,PACSIN2,CDH22,CPEB4,MACC1,RUSC2,HAL,GNE,CDCA8,CRABP2,DSE,PARM1,PPP2R3A,SLC9A2,NRP2,SIRPA,SH2D4A,CD109,GTF2F2,FAM63A,TRIM21,FAIM,SYK,GCNT1,IGDCC4,NFE2L3,DLGAP1,RHOA,FBLN5,NR3C1,AMFR,PPARA,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BCAR1,CD83,PRDX4,SERPINA1,FAT4,TWSG1,SCG2,NMI,TMC5,NETO2,PGRMC1,FAM117A,ICOSLG,UBE2C,TBC1D4,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SUN1,GAA,PPP4R4,LGR4,HSPG2,ATP8A1,PPFIBP2,PLXNA1,CAMK1D,VASH1,PJA2,SLC20A1,FAM101B,CYP1A1,ANKS6,ZNF823,STIM1,ZFP36,RGS3,IQCE,PRICKLE3,AOX1,PIK3CA,ATRNL1,IQCD,HYLS1,SMYD5,METAP2,SGCE,SPATA18,ACVR1C,HSPA12A,NBPF3,KIF13A,TNS1,GALNT7,MCFD2,LDB2,CCNF,ARHGEF26,AHRR,RBM47,PTER,GNPTAB,LRIG1,NKD1,FAM110C,NFKBIZ,TANC2,UNC5B,F2RL1,FGD1,SEMA6B,MRC2,MRPL44,TBC1D1,HLA-E,SLC25A27,KIF23,ISYNA1,KIAA1161,MECOM,DOPEY2,RALGPS2,LYPD3,PIK3AP1,SNX18,BHLHE41,AIM1,RUNDC3B,DAPK1,ADCK2,TPST1,PRKG1,SORL1,C8orf58,CACNA1D,RIMS2,TRAK2,IGSF3,EPB41L5,PMPCB,KCNJ12,FADS2,B3GNT7,MFI2,TBC1D8B,ADCK3,LPGAT1,AMER1,ANO6,PIP4K2C,FAM133B,NPC2,ATP8B3,ANTXR1,GLT8D2,RASA1,FRMD4B,MMP15,DGKH,GABRD,SLCO4A1,PRKAG2,PLEKHH2,TJP3,MATN2,SLC4A3,FGD6,PCDH19,CABIN1,NR4A2,CDK18,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,SPRED1,ST14,NLRX1,IQGAP1,RALBP1,DDIT4L,CCDC110,ATP2C2,BCL2L1,DDR1,MNS1,CYP39A1,ZFYVE9,EPS8L2,APLP2,ACAP2,ZNF75D,FAM46A,TRANK1,EPHB4,PHKA2,LGMN,NAGA,ATG4D,MYO5B,DOCK4,SEC23A,CAPN6,FOXJ2,UTRN,KIF1C,SLC11A2,PKMYT1,C15orf39,ITPR3,SP4,ZNF469,FZD7,PRDM11,NIN,EPHA10,JAK1,NGFRAP1,TRIOBP,SLC27A1,KLF5,SLC27A3,NR3C2,DENND5B,PCOLCE,DEPDC1,ATP9A,EPS8,CCNJL,PBX3,DNAH3,SIX4,HLA-A,LGALS3BP,SLC25A36,WWP2,RASSF8,E2F7,PTEN,FUT8,DRAM1,SLC44A2,TAGLN2,ERBB3,CNOT6L,TRIM62,SLC16A5,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ALDH2,ARAP2,LONRF3,ZC3H11A,ZKSCAN2,FURIN,PARP4,DIAPH2,FOS,CDK5RAP1,MAMDC4,ACADSB,FGFR2,TBX18,ABCB1,PGM2L1,GRIN2D,WDR62,ARSB,ESPL1,MELK,OCLN,JARID2,RGMA,ESYT2,LTBP1,HEBP1,CPT2,VARS2,KREMEN1,TMC1,CHPF,ABCD4,ZFYVE16,ARHGEF10L,SIPA1L2,HSF2,LRRC6,ARHGEF37,ANKFN1,ANKRD12,TRPC1,CTTN,MYH14,MYRIP,RASGRP1,NLRP4,TRIM8,USP18,RGAG1,ROR1,PTGFRN,CXXC4,MAN2A2,LRRC42,ARHGEF19,GPRC5B,UEVLD,MADD,ADIPOR1,PCSK5,NR2C2,GRN,ARAP3,ZNF395,SERPINE2,LRRFIP2,PYROXD2,ETV5,SAMD9,FAM81A,PHLPP1,ADAMTSL4,B3GALNT1,ZNF432,KCNN4,COL6A1,FXYD5,LIMCH1,RFX5,HLA-C,SLC12A2,ETV7,ELK3,PODXL2,OXR1,GYLTL1B,PDE5A,VWA1,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,MUM1L1,SOX13,GLCE,GNAS,FECH,BCAR3,UAP1,CDCA5,ALPK3,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,PROM2,KLF7,CCNE2,LMO7,GAS2L1,LZTFL1,NCKAP5,SLC25A24,SORBS1,MORC4,COL18A1,TDRKH,OSR2,SLC25A48,ZNF687,SETDB2,CYP4F11,ZDHHC12,FRYL,EPB41L4B,SCYL3,MAP3K3,SLC39A8,OSTM1,C3orf52,GLO1,ERBB2IP,DUSP4,CASP4,ARHGAP35,BFSP1,BHLHB9,OVOL1,SPTBN5,CYP2U1,ABCA1,PPP2R2D,FBLIM1,TSPAN15,FRMD6,LRP4,COL4A5,TRMT2B,POMGNT1,SBF1,TMEM63A,HDAC9,TOP2A,CARD8,MLPH,A4GALT,BMP7,RRBP1,GALNS,KIAA0319,ARVCF,IQGAP3,CLIP2,MYO5A,PGM1,PHF20L1,NR4A1,ASPM,RC3H2,OGDHL,LRRC66,TTC7A,KLHL2,ENDOD1,HLA-B,HNRNPH2,DHRS2,RAP2C,DTX4,ARRB1,PLOD3,SOX8,L1CAM |
| 6.751e-05 | -9.60 | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | 186 | 36 | 17758 | 1761 |
PARP12,IL15,ARHGEF11,TRIP10,FTH1,PSME1,CD274,C11orf95,PRRG4,DTX3L,SS18,BTG3,DRAM1,TPST1,TRIM21,IRF2,ECE1,PIM1,CKAP4,PARP9,RIPK2,COQ10B,MICB,NUB1,NFE2L1,RUNX3,PHLPP2,NFKBIA,AGFG2,NFKBIZ,IRF7,CMPK2,IFIH1,JAK3,APOL2,NXT2 |
| 6.751e-05 | -9.60 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | 186 | 36 | 17758 | 1761 |
SUN1,ARHGEF3,FRMD6,DAP,THRA,HAL,ARL4C,MGST2,TRIB2,KBTBD11,PARM1,SYTL2,TTC21B,ZFP36,DLG1,MAPK11,CDKN2D,ALS2CL,SYK,DOCK4,RGMB,ZC3H11A,FOXJ2,MFSD2B,CD40,FOS,ZBTB7B,ATP10D,ATP13A2,NFIX,ALDH5A1,HS3ST3B1,ST3GAL1,USF2,CPEB2,KLF7 |
| 6.751e-05 | -9.60 | GSE27786_BCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKCELL_DN | 186 | 36 | 17758 | 1761 |
FRMD4A,PPM1J,DNAJC3,DSE,B3GALNT1,TNS3,GATA2,IL6ST,ABCD1,KLF9,ALPK1,MARCH2,NCEH1,SPRY2,MCCC2,FARP2,MCTP1,PQLC3,PLSCR1,TNIP1,CITED4,RGMB,GUSB,OSTM1,OXR1,KIF13A,PRKRA,MID1IP1,RBM47,DBI,NLRC5,ARRB1,ADIPOR1,LRRK1,ZMIZ1,ISOC1 |
| 6.751e-05 | -9.60 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 186 | 36 | 17758 | 1761 |
WASF3,COL9A3,TSC22D3,CALB2,SOX9,SLC7A2,OSR2,SYTL2,CCND1,BTG3,B3GALNT1,IGF1R,AIM1,TFAP2A,IGFBP2,EPB41L4B,MINPP1,MYBL1,BTBD3,RASGRP1,CELSR2,SLC39A8,OSTM1,LPGAT1,SH3BGRL,MICB,AK4,PDK3,ALCAM,FOS,MDK,RND3,PLK2,LRIG1,INPP4B,SHROOM2 |
| 6.820e-05 | -9.59 | - | gene3d domains | 2.60.40.150 | 146 | 32 | 9988 | 1080 |
PLA2G4A,RASA2,SYTL4,PKN1,SYTL2,WWP2,CPNE2,RGS3,RIMS3,PLCG2,PIK3CA,DAB2IP,WWP1,PIK3CD,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,PRKCQ,ABR,RASA1,PLCH1,PLCG1,SYT7,RAB11FIP2,RAB11FIP1,INPP4B,PIK3C2B,SYT13,ESYT2 |
| 6.824e-05 | -9.59 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 179 | 35 | 17758 | 1761 |
CCNE2,MRC2,TXN,TSPAN15,TSC22D3,EPS8,CTSZ,BCL2L1,DSE,BARD1,LMNA,GNS,CD109,TAF1B,KCNN4,DPYSL2,N4BP3,PAPSS1,CNNM4,TNFRSF12A,HYLS1,ECE1,F2R,ATP2B1,GCNT1,SNTB2,SAT1,PIK3R1,RUNX3,TP53INP2,FRMD4B,MAPKAPK2,SLCO4A1,PITPNA,CENPE |
| 6.831e-05 | -9.59 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | 158 | 32 | 17758 | 1761 |
CASP3,DLGAP5,CIT,KIF23,CCNB1,CDKN2C,TOP2A,FAM111A,UBE2T,STIM1,NEK2,PLK4,BUB1,CKS2,HMMR,HES1,CENPA,KIF20A,CDC20,NUSAP1,ANLN,CDK1,ABR,IDE,RBL1,CDCA5,AURKA,CENPE,CCNB2,UBE2C,E2F8,MELK |
| 6.837e-05 | -9.59 | negative regulation of cell-substrate adhesion | biological process | GO:0010812 | 49 | 15 | 16441 | 1675 |
AP1AR,NF2,MFI2,ACVRL1,PTEN,FZD4,CORO1C,PIK3R1,TBCD,BCL6,ADAM15,TACSTD2,FBLN1,FZD7,RASA1 |
| 6.865e-05 | -9.59 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | 172 | 34 | 17758 | 1761 |
DDX58,IL15RA,ARHGEF11,HERC5,SAMD9,HERC6,TMCC3,OTUD1,TRANK1,CABP1,FJX1,IFIT1,OAS3,LAMP3,AMOTL2,ARAP2,RIPK2,PLSCR1,SPATA18,IFIT3,NFIX,FAS,GALNT3,MDK,HPSE,C19orf66,ZNF367,NLRC5,IRF7,HS3ST3B1,CMPK2,GLCCI1,RARG,IFI6 |
| 6.869e-05 | -9.59 | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 33 | 17758 | 1761 |
GRN,LAMP1,LGALS3,PDIA5,TGOLN2,F11R,PRRG4,SIRPA,IER3,APLP2,ATP6V0B,GALNS,RRBP1,PPP4R1,RPN2,PDIA6,PTPRE,SLC16A5,S100A6,MYO5A,CKAP4,CYP1B1,CPD,RNF19B,ALCAM,POR,CYP4F3,STX3,MAN2A2,HOXA9,PNPLA6,CLMN,NRG1 |
| 6.869e-05 | -9.59 | KATSANOU_ELAVL1_TARGETS_UP | MSigDB lists | KATSANOU_ELAVL1_TARGETS_UP | 165 | 33 | 17758 | 1761 |
SORT1,NFKBIE,PSME2,EPHA4,CCDC68,GDF15,DNER,FAM101B,DHRS3,PDGFB,FZD6,SYTL2,SUSD2,ITGA3,CTSC,ALDH1A3,FJX1,DAPK1,NTN4,IGFBP2,NOTCH3,PCGF5,TMTC1,SAT1,PDE5A,LDB2,AIF1L,ATP10D,FAS,PITX2,PLEKHH2,PLOD2,MYL12B |
| 6.882e-05 | -9.58 | SH3 | smart domains | SM00326 | 217 | 43 | 9131 | 997 |
BIN1,LASP1,SORBS1,PACSIN2,TRIP10,MACC1,RUSC2,UBASH3B,EPS8,MPP5,TEC,CACNB4,ARHGEF16,SH3KBP1,EPS8L2,ARHGEF37,SNX18,FUT8,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,PLCG1,ARHGEF19,TJP3,SH3BP4,ARHGEF9,RUSC1,ARHGEF4 |
| 6.916e-05 | -9.58 | TIEN_INTESTINE_PROBIOTICS_24HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_DN | 215 | 40 | 17758 | 1761 |
GCLM,ARMCX3,NQO1,ESRP1,PDIA3,FTH1,GDF15,NUCB2,PJA2,PHLDA1,DNAJB9,PDIA4,ELF3,MLPH,RPL39,GOT1,MANF,EPHB4,PDIA6,TRAM1,KDELR1,LAMP3,GFPT1,CLCN3,CD55,SAT1,FNDC3A,RNF19B,RANBP9,ARF4,ARHGAP35,PTPRF,ALDH3B1,DNAJC10,RPL12,WIPI1,H1F0,KLF5,UNC5B,HOOK1 |
| 6.925e-05 | -9.58 | IGF1R signaling cascade | REACTOME pathways | R-HSA-2428924 | 281 | 51 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,IGF1R,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 6.925e-05 | -9.58 | IRS-related events triggered by IGF1R | REACTOME pathways | R-HSA-2428928 | 281 | 51 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,IGF1R,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 6.925e-05 | -9.58 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | REACTOME pathways | R-HSA-2404192 | 281 | 51 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,IGF1R,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 6.977e-05 | -9.57 | positive regulation of peptidase activity | biological process | GO:0010952 | 161 | 33 | 16441 | 1675 |
CASP3,PINK1,PCOLCE,NKX3-1,DAP,PSME2,RET,PSME1,FBLN1,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,DAPK1,BAX,CDKN1B,WNT3A,EGLN3,F2R,SIRT1,RHOA,ACVR1C,CASP9,SLC11A2,FAS,NGFRAP1,ARRB1,GPER1,MAP3K5,MAPK12,XDH |
| 7.009e-05 | -9.57 | carbohydrate derivative metabolic process | biological process | GO:1901135 | 1075 | 148 | 16441 | 1675 |
SLC35D2,ACACB,UGT8,HSPG2,GNPDA1,SLC25A13,HEXB,FBXO2,NANS,MGAT5B,CACNB4,SDC1,CHPF,TYMP,MUC4,IMPAD1,PAPSS1,SERINC2,FUT1,DLG1,AKR1B1,TIPARP,MGAT5,APOBEC3G,TNIP1,CDA,GALNT7,ICMT,MCFD2,ARF4,MAN2A2,HS6ST1,ENPP1,NEIL1,HPSE,DOLPP1,GNPTAB,DHTKD1,GLA,ASAH1,NDUFA4,B4GALT4,ADAMTSL4,B4GALNT1,GNS,B3GALNT1,ATP5H,AHCY,PIM1,PPP6R1,MCCC2,TRAK2,CHSY3,GFPT1,PMPCB,B3GNT7,PQLC3,MGAT4B,GYLTL1B,PDE5A,GLCE,GNAS,NUDT16,PRKAG2,UAP1,DCK,PRPS2,CTSA,PLA2G4A,SLC2A4,UGP2,PAPSS2,IL15,GALNT12,XYLT1,PHLDA1,MUC16,XYLT2,RPN2,PDE4D,DLG3,LMAN1,SULT2B1,NAGA,GM2A,CHP1,SULF2,SIRT1,ENPP4,SEC23A,AKT1,FIGNL1,PANK1,ATP1B1,ALDH5A1,DDOST,ABHD12,SLC27A1,HS3ST3B1,ST3GAL1,NDST3,CMAS,ENO2,SDC4,GNE,PDIA3,APOBEC3H,CTSZ,FBXO6,POMGNT1,DSE,FUT2,ITGB8,CTSC,ARSG,A4GALT,ALG13,MGAT4A,FUT8,GALNS,UBE2J1,BAX,GCNT1,B3GALT6,HMMR,PGM1,SHMT1,B3GNT2,PLSCR1,GUSB,PLAUR,MPP1,OGDHL,PARP4,AK4,C1GALT1C1,COL7A1,ARSK,FOXL1,CPTP,GPLD1,FUCA1,GALNT3,SERPINA1,CMPK2,ARSB,ACOT7,OCLN |
| 7.059e-05 | -9.56 | parotid | COSMIC cancer mutations | parotid | 594 | 88 | 17775 | 1757 |
MFSD3,SLC25A13,RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,SPTB,APPBP2,WEE1,MUC16,RPS6KA2,PQLC2,PAPSS1,DLG1,PIK3CA,SEMA3G,EPHB4,PIK3CD,DLG3,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,SMARCA2,AKT1,CAPN6,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,KLF5,LIFR,HOXC13,MAPK12,PINK1,MRC2,CDK17,CHCHD7,GNE,FAM134A,SLC25A36,NEO1,IGF1R,CDK16,PTEN,MGAT4A,DAPK1,MAP3K9,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,SYK,SUN2,B3GNT2,ADCK3,PIK3R1,ZKSCAN2,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,LRRC1,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,TBC1D4,JAK3 |
| 7.072e-05 | -9.56 | CELL_FRACTION | MSigDB lists | CELL_FRACTION | 486 | 75 | 17758 | 1761 |
LAMP1,IL15,TP53,SLC7A2,MGST2,KREMEN1,CYP39A1,SYTL2,STEAP2,FUT1,ECE1,CTTN,PDE4D,OAS3,CTDSP2,RASGRP1,LAMP2,CPD,PPIF,CD55,MCTP1,SNTB2,UTRN,ARFRP1,PKMYT1,ICMT,DAG1,ATP1A1,IDE,ALDH5A1,SLC9A6,WFS1,ARF6,RAP1GAP,ABCA1,GCLM,TSPAN15,SLC1A3,POMGNT1,FBLN1,MERTK,EFNB1,NRP2,B4GALNT1,ADRBK1,A4GALT,SLC16A6,TPST1,ATP8B1,TMBIM6,TSPAN13,CD70,SLC12A2,SLC16A5,MED22,CKAP4,KDELR1,ABCC1,FADS2,FBLN5,MMD,MPP1,AMFR,RC3H2,BCAR1,FAS,GALNT3,HLA-B,SCARB2,FAAH,SPINT2,SLC4A3,ABCB1,ARRB1,PTGES |
| 7.102e-05 | -9.55 | CUI_TCF21_TARGETS_2_UP | MSigDB lists | CUI_TCF21_TARGETS_2_UP | 414 | 66 | 17758 | 1761 |
PAPSS2,TCTN2,EPHA4,HDAC11,PTTG1,NUF2,SLC7A2,MNS1,PDGFA,UBE2T,CDKN1B,CYP1B1,CAMSAP3,COL6A2,CENPA,CAPN6,SERTAD4,SYNE2,IGSF8,XRCC6BP1,LHFPL2,CDK1,EDNRA,NFIX,PRIM1,CXXC4,MDK,PLCH1,NKD1,SIPA1L1,KLF5,EPB41L4A,CD99,CTHRC1,HJURP,ETV5,CDCA8,BEX2,PARM1,NRP2,HMGXB4,ADD3,FRAS1,RANBP1,COL6A1,IGFBP2,CADPS2,IQGAP3,NCAM1,IGDCC4,HMMR,ADAMTS2,FBLN5,ASPM,ANTXR1,RPL12,FAM64A,MATN2,CDCA7L,CDCA5,SLC4A3,ZMIZ1,CCNB2,UBE2C,ARSB,ESPL1 |
| 7.291e-05 | -9.53 | FERM_N | pfam domains | PF09379 | 29 | 11 | 16629 | 1696 |
EPB41L5,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 7.351e-05 | -9.52 | Collagen biosynthesis and modifying enzymes | REACTOME pathways | R-HSA-1650814 | 64 | 18 | 8202 | 867 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,P3H2,COL18A1,COL4A5,COL7A1,COL12A1,COL13A1,PLOD2,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 7.380e-05 | -9.51 | anchoring junction | cellular component | GO:0070161 | 491 | 76 | 17570 | 1756 |
LMO7,SORBS1,KIAA1462,NF2,ADD1,HSPG2,IQGAP1,PKP2,SDC1,SH3KBP1,CDH1,DLG1,IRF2,CDH3,DIXDC1,CTTN,TLN2,SMAGP,CHP1,CAMSAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,JAK1,SHROOM3,CORO1C,PTK7,LIMK1,TRIOBP,ARF6,HSPB1,CAPN1,CD99,FBLIM1,LASP1,MRC2,PACSIN2,ITGA6,SDC4,KIF23,PDIA3,NCKAP1,TNS3,ITGA3,FLRT3,TBCD,CD9,ADAM15,EPB41L5,PVRL4,RHOA,FMN1,PLAUR,SCRIB,VEZT,YES1,AIF1L,SNTB1,BCAR1,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,PLPP3,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,SHROOM2,L1CAM,AFAP1 |
| 7.437e-05 | -9.51 | positive regulation of proteolysis | biological process | GO:0045862 | 358 | 60 | 16441 | 1675 |
CASP3,PINK1,PCOLCE,NKX3-1,DLGAP5,DAP,DNAJB2,PSME2,RET,PSMD10,PSME1,TRIB2,CCNB1,FBLN1,BCAP31,TFAP4,PSMD1,CARD8,CTGF,CYR61,CTSC,PTEN,DAPK1,BAX,CDKN1B,DAB2IP,EGLN3,WNT3A,F2R,SOCS5,PLK1,SIRT1,RHOA,AKT1,PSMB4,MFI2,ACVR1C,GCLC,CASP9,NUB1,CDC20,FURIN,PRICKLE1,SLC11A2,F12,RNF19B,PSMA4,CDK1,FAS,GPLD1,NGFRAP1,PLK2,AURKA,ARRB1,GPER1,MAP3K5,UBE2C,ESPL1,XDH,MAPK12 |
| 7.468e-05 | -9.50 | single-organism localization | biological process | GO:1902578 | 3285 | 395 | 16441 | 1675 |
SUN1,LAMP1,SLC35D2,ACACB,GAA,ADD1,TSC22D3,SLC25A13,ATP8A1,CACNA2D2,TAP1,TGOLN2,SYTL4,CCNB1,SLC20A1,SLC9A7,NCS1,CALM2,PQLC2,AP1M2,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,TINAGL1,PIK3CD,TMEM37,PACSIN1,XKR8,LAMP2,ORAI2,SLC35C1,PRKAR2B,KIF13A,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,ENPP1,PLCG1,SLC25A4,LIMK1,GNPTAB,ATP7B,TRAF3IP1,NOD2,SARAF,F2RL1,SCN5A,NFKBIE,SLC25A27,NDUFA4,SLC36A4,GPSM2,SLC1A3,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,DOPEY2,SNX18,RIMS3,ATP5H,RPL39,SLC16A6,PCYOX1,SORL1,CADPS2,PANX2,CACNA1D,PIKFYVE,SYTL3,NUP85,PPP6R1,RIMS2,TRAK2,PMPCB,KCNJ12,SLC37A1,MFI2,CALM1,ANO6,ERO1A,NPC2,ATP8B3,PCTP,SFXN5,STX3,CYB5A,SLCO4A1,CACHD1,AP1AR,GABRD,SCARB2,PRKAG2,SLC4A4,TIMM8A,ITPR1,SLC4A3,NDE1,ARPC2,HOOK1,NRBP1,NUP58,XDH,EHD1,PLA2G4A,MFSD3,MTM1,CCDC109B,SLC2A4,DLGAP5,THRA,RALBP1,ATP2C2,PKP2,FTH1,BCL2L1,PRKACA,DDR1,ZFYVE9,CCND1,SCNN1A,CDH1,CDKN1B,CNNM4,ACSL4,ARL4D,DLG3,RAB27B,SCN3A,ATG4D,MYO5B,SEC23A,SEC61B,COG2,FZD4,SYNE2,KIF1C,NUSAP1,SLC11A2,ATP1B1,RAB38,ITPR3,ATP10D,DDOST,CORO1C,SLC9A6,AXL,SLC27A1,SLC25A30,DENND5B,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,CYB561,ANO9,SLC25A43,PDIA4,SLC25A36,ADD3,SLC27A6,CTSC,SGK3,CD9,BAX,KLC3,ATP8B1,PLEKHF1,SLC44A2,WWP1,SLC16A5,SPRY2,TPCN1,S100A6,NCOA2,LCA5,ZC3H11A,RAPGEF2,PIK3R1,MRS2,GRIN1,FURIN,YES1,NEURL1B,CPTP,GPLD1,RPL12,FGFR2,RAB11FIP2,SYT7,ABCB1,NR4A3,GRIN2D,ITGAV,CENPE,ARSB,USF2,ESPL1,CYBRD1,ESYT2,EXPH5,CRYM,CPT2,ARFGEF1,NDC80,F11R,MPP5,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,SLC8B1,TMC1,ABCD4,ZFYVE16,RAB15,DPYSL2,SLC44A1,ABCA2,DLG1,TRPC1,SUN3,RAB20,RP2,TLN2,SLC39A10,ANO4,TRAM1,S100A13,RASGRP1,KCNIP3,CENPA,CELSR2,EZR,ARFRP1,ADRBK2,OPTN,EDNRA,TRIM9,KCNMB4,KCNK1,WIPI1,RAB11FIP1,PIEZO1,PCSK5,PRKAA2,GRN,LASP1,PEX6,FXYD3,SLC22A31,ETV5,ABCG2,CALM3,NCKAP1,RAB6A,ANO1,CA2,GATA2,KIF13B,KCNN4,EXOC8,FXYD5,SELK,GAD1,SLC12A2,MDFI,ABCC1,KDELR1,BTN3A2,STRADB,SCRIB,EIF2AK1,MFSD7,STEAP1,GNAS,SLC6A6,TMEM30A,MFSD2A,CDCA5,NFKBIA,SLC2A6,SH3BP4,ZDHHC7,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,JAK3,TOB1,APOL2,NIPA1,SLC25A24,SORBS1,UPF3B,TP53,SLC7A2,EMP2,BCAP31,SYTL2,TTC21B,PDGFA,SLC25A48,ATP6V0B,SVBP,KIF14,ZDHHC12,PLCG2,FABP6,REEP1,BCL6,ZDHHC23,RPN2,SCN2A,LMAN1,F2R,GM2A,CHP1,PPIF,CLCN3,AKT1,SLC39A8,OSTM1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,ALDH5A1,PEX2,SPTBN5,SYT13,ABCA1,ANXA3,PINK1,MFSD14B,SORT1,CD63,TSPAN15,LRP4,CDCA8,GABRG2,PSMD10,AIP,VPS26A,HMGXB4,SLC9A2,ZDHHC21,M6PR,TMEM63A,KIF5B,ADORA1,ADRBK1,LLGL2,CDK16,SGK1,ABCD1,SYK,MYO5A,ATP2B1,SUN2,HES1,RAB3B,FBLN5,CRB3,ASPM,PPARA,PRICKLE1,COL7A1,BBS2,SCRN2,SERPINA1,SCG2,TMC5,ARRB1,MCUR1,SPCS3,NDFIP1,ARHGEF9,ABCG1,SNPH |
| 7.567e-05 | -9.49 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | 487 | 75 | 17758 | 1761 |
CCNI,SSH1,TP53,DNAJB11,BCL2L1,CAMK1D,APPBP2,RAD23A,CALM2,EPCAM,SIPA1L2,SESN3,ST5,FRYL,DPYSL2,KLF3,MANF,SLC39A10,TIAM1,ZNF462,SMARCA2,TRIM8,TIMP2,SERTAD3,ATP1B1,LDB2,PTGFRN,NFIX,PTPRJ,DDOST,KCNK1,PTK7,DOLPP1,ZNF704,TRIOBP,ADIPOR1,SP6,ANXA9,SYT13,ISOC1,GRN,IER5L,CD99,GOLIM4,ITGA6,SOX9,CALM3,NDUFA4,SPR,FBLN1,ETS1,DHRS3,PDIA4,DAZAP1,IGF1R,GATA2,FRAS1,CALD1,PIKFYVE,MYLIP,MDFI,BCL9,CALM1,RC3H2,FURIN,LITAF,HMG20B,BSDC1,SMTNL2,FAT4,RND3,KBTBD2,NR4A2,PLIN3,JARID2 |
| 7.577e-05 | -9.49 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 187 | 36 | 17758 | 1761 |
PARP12,HERC5,FBXO6,SNN,HERC6,HMGXB4,DTX3L,RCN1,SIPA1L2,TNS3,FAM46A,SP100,PIK3AP1,IFIT1,CTTN,OAS3,CKAP4,LAMP3,PARP9,REC8,MX1,PLSCR1,USP18,UTRN,BLVRA,IFIT3,TXNDC11,MAN2A2,SCARB2,HPSE,TRIM69,C19orf66,NOD2,IRF7,KLF11,IFI6 |
| 7.577e-05 | -9.49 | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | 187 | 36 | 17758 | 1761 |
SPRED1,SORT1,BLVRB,HAL,ASAH1,FTH1,CTSZ,TMEM170B,SNN,GSTP1,ADAMTSL4,TTYH3,BMP2K,HDAC9,APLP2,DAPK1,CD9,RAB20,PTPRE,C9orf72,SYK,CCDC88A,PDGFC,PLSCR1,PRKAR2B,C15orf39,PCTP,ADRBK2,TP53I3,CRISPLD2,PRCP,CORO1C,SLC2A6,ZDHHC7,LTA4H,ARSB |
| 7.577e-05 | -9.49 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | 187 | 36 | 17758 | 1761 |
ARHGAP11A,SLC35D2,ENO2,NQO1,GNPDA1,PBX3,ASAH1,CYB561,NUCB2,SYTL2,APOBEC3B,EPCAM,CDKN2C,WEE1,NPNT,KIF13B,FUT8,SNX16,CD70,HLA-C,LGMN,LOC81691,LPGAT1,STMN3,YES1,OPTN,HLF,PTPRJ,UEVLD,PHLPP2,RYK,ABCB1,CAB39,FZD5,ARSB,EHD1 |
| 7.577e-05 | -9.49 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 187 | 36 | 17758 | 1761 |
ZMAT1,HECA,UPF3B,CPEB4,LGALS3,CAST,CD274,RAB6A,TRIB2,ETS1,TTYH3,SYTL2,IL17RB,TMEM87B,RALGPS2,ZCCHC12,AIM1,ARMCX6,CITED2,DLG3,RASGRP1,ALDH2,NR4A1,RAPGEF2,BCL9,PTGER4,SCRIB,GALNT7,ZBTB7B,SWAP70,DOLPP1,RAP2C,INPP4B,RGS14,TOB1,JARID2 |
| 7.577e-05 | -9.49 | ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 187 | 36 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,PDIA3,ERP29,BARD1,AIP,ZFYVE9,APPBP2,PDIA4,ATG4A,ZFYVE16,CARD8,AP1M2,CDH1,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,KDELR1,ATG4D,MDFI,AKT1,COG2,STRADB,ICMT,OPTN,KLHL2,SCG2,NOD2,CTSA,LTBP2,ABCA1,ABCG1 |
| 7.577e-05 | -9.49 | GSE7852_TREG_VS_TCONV_THYMUS_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_DN | 187 | 36 | 17758 | 1761 |
EXPH5,ATP8A1,ARL4C,TMEM170B,GRK6,FAM101B,SLC20A1,KREMEN1,DENND2D,FZD6,RABGGTA,TMEM63A,B3GALNT1,OTUD1,ZCCHC12,CYP2S1,ZFP36,MITF,SRR,SGK1,FAM102A,MYLIP,ALS2CL,SLC16A5,CTDSP2,SCN3A,LOC81691,TIMP2,HPS3,F12,NPC2,XKRX,KCNMB4,GPRC5B,SLC9A6,RAP2C |
| 7.720e-05 | -9.47 | thyroid | COSMIC cancer mutations | thyroid | 10345 | 1097 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,ISOC2,LACTB2,DPP8,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,CLDN4,TMEM37,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,NXT2,SCN5A,ITGA6,GPSM2,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,FRY,MEGF8,RIMS3,FLRT3,PCYOX1,MAP3K9,ALPK1,PANX2,ZMYM1,DGKG,ULBP2,PPP6R1,HPS3,ELK1,NPHP3,PCTP,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,GDF11,TMEM173,ADAMTS16,DOCK9,RNF224,TPRN,GRK6,REPS1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,ZNF365,MYT1,MX1,COL6A2,C6orf1,APOBEC3D,SEPT6,HTATIP2,ZNF618,PDLIM3,SHROOM3,WFS1,AXL,PNPLA6,ISOC1,MAPK12,ESRP1,HABP4,SDC4,BTN3A1,SLC25A43,FUT2,ITGB8,IGSF9,CST3,KLC3,PARP9,ACBD5,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,UBE2A,AK4,CNTNAP1,RPL12,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,IL6ST,PAPSS1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,CBX6,CR2,ARFRP1,SESN1,DZIP1L,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,HOXA9,ARRDC1,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,HES2,FBLN1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,AHCY,FAR2,WNT3A,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,SCRIB,PDK3,PRX,RASGRP2,FOXD2,COL13A1,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,TP53,STIL,BCAP31,SYTL2,PDGFA,TTC21B,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,IRF7,SYT13,ST3GAL1,ZMAT1,BIN1,PINK1,CDH22,CPEB4,KLHL13,GTF3A,GDF15,LBR,AIP,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,M6PR,CD109,FOXP2,ALPP,TFAP2A,GTF2F2,FAM63A,SGK1,SYK,GCNT1,WBP5,NFE2L3,HES1,FBLN5,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SMTNL2,ICOSLG,PTGES,ARHGEF4,GOLGB1,SLC35D2,LGR4,HSPG2,SSH1,VANGL1,TSC22D3,PSME1,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,SPATA18,SLC35C1,KIF13A,LDB2,POR,ANKRD10,LRIG1,PRDM5,BMP1,NFKBIZ,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,TBC1D1,TMEM55B,TNFRSF19,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,ATP8B3,ANTXR1,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,DDIT4L,ATP2C2,TMEM170B,DDR1,ZFYVE9,EPS8L2,APOBEC3B,NOV,TRANK1,EPHB4,PDE4D,ATG4D,DOCK4,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,PYGO1,ITPR3,ALCAM,ATP10D,FZD7,AMZ2,DDOST,NGFRAP1,TSPAN18,TRIOBP,FAM195A,SLC27A3,PRR15,COBL,HAPLN3,CENPI,DNAH3,EFNB1,HLA-A,WWP2,E2F7,TMEM87B,RNF128,FJX1,DRAM1,ERBB3,CITED2,SLC16A5,FARP2,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,YES1,FOS,ARSK,CDK5RAP1,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,CXorf56,MELK,RGMA,UGT8,CRYM,VARS2,ERP29,TRIM68,HTR1D,EPCAM,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,CEP78,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,KCNK1,MADD,ZNF165,GLA,LASP1,ARAP3,ZNF395,SERPINE2,PYROXD2,ETV5,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,SNX7,TPGS2,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,MFSD7,RANBP9,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,APOL2,LMO7,DYNLRB1,NCKAP5,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,ECE1,PTPRU,CASP4,ARHGAP35,ALDH5A1,SECTM1,SPTBN5,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,COL4A5,INTS8,SBF1,NTAN1,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,BMP7,RRBP1,ARVCF,CLIP2,MYO5A,RC3H2,TTC7A,RUNX3,LEPR,ENDOD1,TRIM69,SPINT2,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,KLK10,IL15RA,MMADHC,CACNA2D2,NRG2,DHX8,SYTL4,MORF4L2,BARD1,EPDR1,DAPK2,CALM2,WEE1,KIAA1107,CYP2S1,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,SEMA3G,APOBEC3G,ERAP2,SMARCA2,SPEF2,NWD1,TNIP1,SERTAD4,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,ANKRD6,DNM1L,LIMK1,SERPINB6,E2F8,GAB1,SOX9,MERTK,LMNA,ELF3,RAVER2,FAM189A1,C9orf72,SLC37A1,SALL4,STAT4,MYBL2,CYB5A,DCP2,DHX32,PTPRF,NCOA3,ITPR1,AURKA,DRP2,ZNF502,EGLN1,XDH,MTM1,CCDC109B,PAPSS2,TMSB15A,GALNT12,ACTR8,PKP2,PRSS22,APC2,CCND1,SCNN1A,SCN3A,SSH3,CAMSAP3,CYS1,SYNE2,CDCA2,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,HOXB2,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,ANKS1B,CALD1,ADAM15,MAPK11,WWP1,NPTXR,S100A6,CRTAP,AMOTL2,LCA5,FMN1,RAPGEF2,MFSD2B,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,CENPE,CYBRD1,UNKL,SIGIRR,TRIM2,GNPDA1,PPM1J,EPHA4,FHDC1,TP53I11,HDAC6,NUP62CL,SHC3,MKRN3,TLN2,ANO4,TRAM1,MYBL1,S100A13,NEB,DDX59,CCDC38,ZNF462,ING1,CITED4,EZR,ANLN,PRKRA,IDH1,LHFPL2,DPYSL3,PLCH1,MFAP3L,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,GLCCI1,PRKAA2,HLA-F,UBASH3B,CNTNAP2,B4GALT4,DAZAP1,IGF1R,GATA2,SPIN4,PLCB2,C9orf9,ABCC1,CHSY3,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,G2E3,MAPKAPK2,COQ10A,ITGA7,PRPS2,LTBP2,NIPA1,RNF146,AVPI1,UPF3B,NF2,FOXM1,XYLT1,ERBB2,LPIN3,ATP6V0B,EFR3A,PLCG2,LHX6,N4BP3,SRR,SCN2A,MINPP1,DVL2,CTH,SIRT1,TMTC1,FIGNL1,CDC20,DUOX1,PRRT4,ATP1A1,PTK7,ADAMTS14,ANXA9,AIFM3,NDST3,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,PSMD10,NKRF,DSE,SIRPA,SLC9A2,ABCD1,IGDCC4,DLGAP1,PSMB4,AMFR,PPARA,FNDC3A,BCAR1,MAPK8IP1,FUCA1,BANK1,FAT4,SERPINA1,NMI,NETO2,UBE2C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,TTC39B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SESN3,IQCE,RGS3,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,XKR8,LAMP2,LOC81691,ORAI2,TMEM68,KIFC2,SNTB2,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,MCFD2,SLC25A5,ZFAND5,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,GNPTAB,PLK2,NKD1,FAM110C,DHTKD1,UNC5B,LZTS1,DDX58,FRMD4A,HLA-E,DGKQ,C6orf106,KIF23,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,IGSF3,EPB41L5,MMD,MFI2,TBC1D8B,ANO6,AMER1,PIP4K2C,VEZT,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,TMEM54,DCK,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,FRMPD3,ARMCX3,CEP70,NLRX1,TRIP10,RPS6KA1,IQGAP1,BROX,AIFM2,TMPRSS4,MNS1,ZNF75D,FAM46A,CDKN1B,CNNM4,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,NIN,PRDM11,EPHA10,JAK1,NRG1,HS3ST3B1,NR3C2,DENND5B,WASF3,PCOLCE,APOBEC3H,CYB561,SEPP1,SPR,SIX4,LGALS3BP,TEAD3,TMCC3,SNTA1,FAM111A,PHF7,PTEN,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,PGM2L1,GRIN2D,ETAA1,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,EMX1,NMRK1,CASP3,LTBP1,HEBP1,DENND2D,TMC1,KREMEN1,PTCHD4,SH3KBP1,TSEN34,ABCD4,CHPF,ARHGEF10L,ZCCHC12,IMPAD1,DLG1,ANKRD12,POF1B,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ASCL5,ROR1,PTGFRN,STK17B,LRRC42,CXXC4,MDK,ARHGEF19,ADIPOR1,LEMD1,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,OTUD1,AIM1L,KCNN4,FXYD5,RFX5,NCEH1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,AMDHD1,GLCE,GNAS,FECH,BCAR3,SLC6A6,CGREF1,NFKBIA,RHOBTB2,ALPK3,PITPNA,PROM2,GAS2L1,SLC25A24,SPC25,SS18,SETDB2,FRYL,ZDHHC12,TWIST1,RPN2,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,IGSF8,ERBB2IP,DOCK5,KCTD2,BHLHB9,PEX2,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,POMGNT1,FAM167A,SAC3D1,IRF2BPL,IL17RB,MDM1,MLPH,ADORA1,GALNS,KIAA0319,IQGAP3,SUN2,ASPM,NR4A1,LRRC66,MBNL3,OGDHL,KLHL2,HLA-B,C2orf70,DHRS2,HNRNPH2,HOXB13,SOX8,L1CAM,SNPH |
| 7.723e-05 | -9.47 | ribonucleotide binding | molecular function | GO:0032553 | 1843 | 235 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,ARFRP1,KIF13A,PIF1,ROR1,CDK1,POR,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,BVES,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,PDE5A,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,TMEM173,EHD1,UGP2,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,PDE4D,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RAB3B,RHOA,RAPGEF2,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 7.745e-05 | -9.47 | OKUMURA_INFLAMMATORY_RESPONSE_LPS | MSigDB lists | OKUMURA_INFLAMMATORY_RESPONSE_LPS | 173 | 34 | 17758 | 1761 |
MTM1,TXN,RUNX2,GALNT12,ETV5,SDC4,PRSS22,IL27RA,DSE,PHLDA1,FZD6,SIRPA,SGPL1,TNS3,CITED2,MAST4,RASGRP1,PPIF,NFE2L3,ORAI2,TNIP1,PTGER4,SLC11A2,PKMYT1,RAB38,ALCAM,CYB5A,OPTN,NCOA3,DHRS2,TLE1,GDF11,CCNB2,APOL2 |
| 7.745e-05 | -9.47 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | 173 | 34 | 17758 | 1761 |
EMX1,MORC4,CYB561,HMGN3,ISYNA1,MORF4L2,MGST2,GSTP1,FAM46C,LMNA,IL17RB,METTL7A,MEGF8,OSBPL3,CST3,SGK3,RPN2,PACSIN1,LMAN1,CCDC88A,WBP5,FBXL16,SYNE2,ZKSCAN2,PARP4,GGH,RANBP9,TP53I3,PRDX4,CXXC4,MAP2,CGREF1,SPCS3,GLCCI1 |
| 7.759e-05 | -9.46 | platelet-derived growth factor receptor signaling pathway | biological process | GO:0048008 | 34 | 12 | 16441 | 1675 |
PDGFA,PDGFC,PTPRJ,PTEN,IQGAP1,RGS14,PDGFB,BCAR1,TIPARP,ZFAND5,GAB1,SGPL1 |
| 7.770e-05 | -9.46 | negative regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070303 | 39 | 13 | 16441 | 1675 |
PINK1,AKT1,FOXM1,DACT1,ITCH,PBK,DLG1,DUSP10,EZR,F2RL1,GSTP1,HIPK3,MECOM |
| 7.770e-05 | -9.46 | negative regulation of stress-activated MAPK cascade | biological process | GO:0032873 | 39 | 13 | 16441 | 1675 |
PINK1,AKT1,FOXM1,DACT1,ITCH,PBK,DLG1,DUSP10,EZR,F2RL1,GSTP1,HIPK3,MECOM |
| 7.792e-05 | -9.46 | upper_aerodigestive_tract-mouth-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma | 6709 | 737 | 17775 | 1757 |
HECA,ACACB,KLK10,ADD1,MRPS15,AK7,RET,DHX8,NRG2,LACTB2,CA8,BARD1,CARD10,LTBP3,GRM5,PSMD1,PQLC2,AP1M2,KIAA1107,PAQR5,ALDH1A3,SEMA3G,PIK3CD,MANF,TIAM1,MGAT5,ERAP2,DNAAF3,NWD1,SMARCA2,FBXL16,MTRF1L,TMEM151A,TFAP2C,PRKAR2B,LOXL2,F12,COL12A1,ABR,ARF4,PIAS3,ENPP1,PLCG1,ANKRD6,ATP7B,LIMK1,NOD2,AGFG2,HDAC1,TMOD2,ITPKA,NXT2,SCN5A,ALDH6A1,FAM169A,GGA1,ITGA6,MTL5,SLC36A4,MERTK,LMNA,RABGGTA,FRY,MEGF8,MAP3K9,ALPK1,PANX2,ZMYM1,NCAM1,DGKG,PPP6R1,C9orf72,KIF20A,STAT4,MYBL2,ELK1,NPHP3,SPTLC2,SFXN5,GNA11,PLIN5,CYB5A,PTPRF,SLC4A4,ETS2,SETD3,ITPR1,CLMN,MDH1,DRP2,NDE1,ZNF502,XDH,ADAMTS16,DOCK9,ARHGAP11A,TPRN,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PRSS22,NUF2,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,RCN1,MUC16,RNF220,ST5,SCNN1A,CDH1,DACT1,XYLT2,RTKN2,ACSL4,RASGEF1A,RAB27B,LRP11,DLG3,ZNF365,MYT1,TMEM9,SCN3A,ENPP4,MX1,CAMSAP3,SSH3,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,PLEKHO1,SYNE2,XRCC6BP1,ZNF618,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,SIPA1L1,PLEKHG1,PNPLA6,RGS14,ISOC1,TTC8,NKX3-1,TNRC6C,ESRP1,OSGIN2,BTN3A1,PDIA3,CTSZ,ANO9,PKN1,SRPX2,PDIA4,ITGB8,ANKS1B,CTSC,ARSG,KLC3,PLEKHF1,IGFBP2,NPTXR,TPCN1,PARP9,AMOTL2,PVRL4,ADAMTS2,FAM160A1,RAPGEF2,NUB1,GRIN1,CXorf57,SNTB1,CNTNAP1,SYT7,ACVRL1,CENPE,ITGAV,OSR1,CMPK2,DCBLD1,CYBRD1,ACOT7,TLL2,ILDR1,BCAM,GNPDA1,FAM199X,CNOT8,CUL4B,FHDC1,LMCD1,NDRG2,TEX2,MGAT5B,HDAC6,SDC1,SPTB,FANCI,SUSD2,BTG3,ELF5,MITF,TMEM143,ABCA2,NTN4,ANO4,TLN2,DDX59,NEB,ZNF462,PCGF5,MCTP1,KCNIP3,CELSR2,EZR,CR2,ANLN,ZBTB7B,DPYSL3,TRIM9,PLEKHG6,PLCH1,KCNMB4,ZNF367,RAB11FIP1,ARRDC1,PIK3C2B,PIEZO1,EPB41L4A,PRSS8,PRKAA2,RUNX2,HJURP,HLA-F,CNTNAP2,FBLN1,IL18R1,TNS3,DAZAP1,RINL,FRAS1,TBCD,AHCY,FAR2,WNT3A,ALDH3A2,CKAP4,ABCC1,C9orf9,CYP26B1,CHSY3,PCDH1,PLEKHA6,PCBP3,MGAT4B,SPATA13,SCRIB,EIF2AK1,PDK3,G2E3,PRX,EPN3,COL13A1,KBTBD2,PHLPP2,MFSD2A,ITGA7,SLC2A6,NLRC5,LTBP2,PLD1,SEMA3A,RNF146,USP43,HOXB7,XYLT1,TP53,CCDC68,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,LMO4,PLCG2,PLK4,ZDHHC23,CDH3,GLB1L2,NOTCH3,OAS3,EGLN3,SCN2A,CTDSP2,GM2A,DVL2,CTH,CPD,DAG1,ATP13A2,DNAJC10,DUOX1,TAPBP,ATP1A1,IDE,C19orf66,ABHD12,RBL1,PTK7,STK38,ADAMTS14,C1orf43,AIFM3,ZNF701,NDST3,PINK1,TM2D2,PACSIN2,CDH22,GNE,CDCA8,GDF15,DSE,PARM1,SLC9A2,SH2D4A,CD109,C16orf74,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,ABCD1,KLF9,SYK,TLE6,ATP2B1,GCNT1,IGDCC4,NFE2L3,FBLN5,MOSPD2,AMFR,PPARA,MAML2,COL7A1,FNDC3A,RNPEP,TXNDC11,BCAR1,CD83,BANK1,SERPINA1,FAT4,TWSG1,ICOSLG,UBE2C,TBC1D4,HIPK3,ARHGEF4,GOLGB1,DIS3L,GAA,PPP4R4,HSPG2,LGR4,TSC22D3,ATP8A1,PPFIBP2,PLXNA1,VASH1,PJA2,OAT,SLC20A1,FAM101B,NCS1,SESN3,ANKS6,ELMO2,STIM1,RGS3,OSBPL3,PRICKLE3,IL31RA,SERINC2,PIK3CA,KCNS3,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,LOC81691,SGCE,KIFC2,SPATA18,ACVR1C,HSPA12A,SLC35C1,KIF13A,GALNT7,LDB2,CCNF,POR,SPNS3,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,EIF4EBP2,UNC5B,TANC2,TRAF5,LZTS1,FGD1,SEMA6B,MRC2,TBC1D1,HLA-E,CALB2,SLC25A27,SLC1A3,PSIP1,KIAA1161,DOPEY2,LYPD3,BHLHE41,VASN,DAPK1,ADCK2,PRKG1,SORL1,CD70,C8orf58,CACNA1D,PIKFYVE,SYTL3,TRAK2,IGSF3,B3GNT7,MFI2,TBC1D8B,ADCK3,AMER1,ANO6,ATP8B3,RASA1,FRMD4B,MMP15,DGKH,GABRD,SLCO4A1,PLEKHH2,TJP3,FAM64A,MATN2,SLC4A3,FAM83D,FGD6,SFMBT1,PCDH19,CABIN1,KLK7,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,SLC2A4,REPS2,DLGAP5,ARMCX3,ST14,NLRX1,IQGAP1,DDIT4L,CCDC110,DDR1,CYP39A1,EPS8L2,APLP2,DOK4,CDKN1B,EPHB4,PHKA2,SULT2B1,NR2C1,NAGA,GPX4,MYO5B,DOCK4,COG2,UTRN,TMEM144,KIF1C,PKMYT1,C15orf39,ASB13,ITPR3,ALCAM,SP4,FZD7,ZNF469,NIN,AMZ2,EPHA10,JAK1,NGFRAP1,TRIOBP,FAM195A,SLC27A1,KLF5,COBL,DENND5B,DEPDC1,EPS8,HERC5,CYB561,APOBEC3H,DNAH3,LGALS3BP,SLC25A36,WWP2,RASSF8,E2F7,FAM111A,PTEN,FUT8,DRAM1,SLC44A2,TAGLN2,ERBB3,CNOT6L,TRIM62,NCOA2,OSGIN1,RASGRF1,PDGFC,ALDH2,ARAP2,LONRF3,ZKSCAN2,FURIN,PARP4,DIAPH2,LRRC1,FOS,CDK5RAP1,MAMDC4,FGFR2,TBX18,AMMECR1,ABCB1,CSTF2,GRIN2D,ETAA1,WDR62,ARSB,ESPL1,MELK,OCLN,JARID2,RGMA,ESYT2,EXPH5,LTBP1,UGT8,VARS2,KREMEN1,TSEN34,CHPF,ABCD4,EPCAM,ZFYVE16,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,SIVA1,CEP78,ANKFN1,POF1B,ANKRD12,TRPC1,RAB20,MYH14,PTPRE,RASGRP1,ATL1,ITCH,RGAG1,ROR1,LRRC42,MAN2A2,ARHGEF19,GPRC5B,MADD,ADIPOR1,SP6,GLA,RAP1GAP,GRN,ARAP3,ZNF395,SERPINE2,LRRFIP2,PEX6,PYROXD2,ETV5,FAM81A,PHLPP1,ADAMTSL4,B3GALNT1,ZNF432,COL6A1,LIMCH1,ZRANB1,SLC12A2,GAD1,ETV7,ELK3,GYLTL1B,PDE5A,HMG20B,VWA1,HEATR5A,MFSD7,MUM1L1,SOX13,GLCE,RHOBTB2,ALPK3,CTSA,SHROOM2,JAK3,RARG,SNX30,KLF7,PROM2,LMO7,GAS2L1,LZTFL1,NCKAP5,SLC25A24,SORBS1,PSME2,HDAC11,PDIA5,COL18A1,OSR2,PHLDA1,KCTD9,LRRC45,SLC25A48,SS18,ZNF687,CYP4F11,ZDHHC12,FRYL,DIXDC1,EPB41L4B,SCYL3,FRS3,MAP3K3,PTPRU,GLO1,IGSF8,ERBB2IP,CD40,DUSP4,DOCK5,CASP4,ARHGAP35,BFSP1,SPTBN5,CYP2U1,ABCA1,LIFR,TSPAN15,ARHGEF11,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,SBF1,KIF5B,TOP2A,CARD8,A4GALT,BMP7,RRBP1,KIAA0319,IQGAP3,CLIP2,MYO5A,B3GALT6,PHF20L1,RAB3B,NR4A1,ASPM,RC3H2,LRRC66,OGDHL,TTC7A,LEPR,KLHL2,ENDOD1,TRIM69,DTX4,UACA,ARRB1,ZMIZ1,PLOD3,SOX8,GEM,L1CAM,RAB3IL1 |
| 7.865e-05 | -9.45 | breast-other-adenosis | COSMIC cancer mutations | breast-other-adenosis | 30 | 11 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 7.865e-05 | -9.45 | adenosis | COSMIC cancer mutations | adenosis | 30 | 11 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 7.912e-05 | -9.44 | WGTTNNNNNAAA_UNKNOWN | MSigDB lists | WGTTNNNNNAAA_UNKNOWN | 512 | 78 | 17758 | 1761 |
EMX1,SPC25,HOXB7,TEX2,SLC20A1,PDGFB,CYP26A1,IER3,CDKN2C,SHC3,RGS3,XYLT2,LMO4,ALDH1A3,KLF3,MITF,BCL6,MANF,RASGEF1A,TIMP2,CAPN6,SYNE2,KIF13A,ROR1,ANLN,LDB2,SP4,COL12A1,FZD7,STK38,HOXA9,NRG1,KLF5,HOXC13,IGFBP6,KLHL13,POC1B,ETV5,TNFRSF19,DHRS3,H1FX,SIRPA,PPP2R3A,HDAC9,MECOM,FOXP2,DTX3L,GNB5,ADRBK1,IGF1R,GATA2,CALD1,TOX2,SGK3,TFAP2A,ZRANB1,NCAM1,GAD1,TGIF1,OXR1,PIK3R1,MBNL3,FNDC3A,FOS,C3orf58,NFIB,PRDX4,PTPRF,PITX2,EPN3,ETS2,AMMECR1,NR4A3,RHOBTB2,NR4A2,DRP2,KLF7,JARID2 |
| 7.922e-05 | -9.44 | PROTEIN_LOCALIZATION | MSigDB lists | PROTEIN_LOCALIZATION | 209 | 39 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,BARD1,ERP29,AIP,ZFYVE9,APPBP2,PDIA4,ATG4A,ZFYVE16,AP1M2,CARD8,CDH1,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,KDELR1,MDFI,ATG4D,AKT1,COG2,STRADB,ICMT,OPTN,KLHL2,SCG2,SHROOM3,NOD2,CTSA,LTBP2,SHROOM2,ABCA1,ABCG1 |
| 7.923e-05 | -9.44 | YU_MYC_TARGETS_UP | MSigDB lists | YU_MYC_TARGETS_UP | 40 | 13 | 17758 | 1761 |
TOP2A,PLK1,TXN,KIF20A,ASPM,AURKA,BUB1,CCNB1,ANLN,CCNB2,CDK1,E2F8,CKS2 |
| 7.931e-05 | -9.44 | FURUKAWA_DUSP6_TARGETS_PCI35_DN | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_DN | 68 | 18 | 17758 | 1761 |
ARHGAP11A,CCNE2,CENPA,DLGAP5,HJURP,CKAP2,PBK,CALB2,NUSAP1,CCNB1,STIL,KIF11,ETS1,PRIM1,AURKA,ACOX2,CCNB2,MAFF |
| 7.964e-05 | -9.44 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | 74 | 19 | 17758 | 1761 |
GCLM,GDF15,C15orf39,MERTK,GABARAPL1,PGF,HS6ST1,NCOA3,ZFP36,ANKRD12,CCDC82,SGK1,NRG1,TIPARP,CLIP2,SPRY2,HIPK3,AHR,NIPA1 |
| 7.964e-05 | -9.44 | PID_AVB3_INTEGRIN_PATHWAY | MSigDB lists | PID_AVB3_INTEGRIN_PATHWAY | 74 | 19 | 17758 | 1761 |
COL9A3,RHOA,COL6A2,AKT1,PIK3R1,COL4A5,F11R,COL7A1,BCAR1,SDC1,COL12A1,IGF1R,COL13A1,CSF1,COL6A1,PIK3CA,CDKN1B,ITGAV,COL16A1 |
| 8.102e-05 | -9.42 | SIMBULAN_PARP1_TARGETS_UP | MSigDB lists | SIMBULAN_PARP1_TARGETS_UP | 30 | 11 | 17758 | 1761 |
CCND1,ANXA3,NOV,TIMP2,TIMP3,SERPINE2,IGFBP6,COL4A5,CTTN,TINAGL1,S100A6 |
| 8.102e-05 | -9.42 | RODRIGUES_NTN1_AND_DCC_TARGETS | MSigDB lists | RODRIGUES_NTN1_AND_DCC_TARGETS | 30 | 11 | 17758 | 1761 |
ARHGEF3,MMD,CDKN1C,ETS2,KIF13B,PPARA,NFKBIZ,KLF9,TBC1D4,FOS,ELF3 |
| 8.102e-05 | -9.42 | KIM_LRRC3B_TARGETS | MSigDB lists | KIM_LRRC3B_TARGETS | 30 | 11 | 17758 | 1761 |
HLA-B,TAPBP,SERPINA1,PSME2,HLA-E,TAP1,FTH1,IFIT1,HLA-C,HLA-A,GM2A |
| 8.106e-05 | -9.42 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 1138 | 155 | 16441 | 1675 |
TXN,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PIK3CA,DLG1,SLC39A10,RASGRP1,PLK1,PRKAR2B,CDK1,EDNRA,PLCG1,GPRC5B,ANKRD6,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,PRKAA2,PIFO,ITGA6,RASA2,SOX9,CALM3,TEC,IGF1R,CYR61,MAP3K9,MDFIC,PIM1,MYDGF,NCAM1,WNT3A,CCDC88A,GPR161,MDFI,MMD,CALM1,PDE5A,STRADB,PSMA4,CDK5R1,RASA1,FAS,GNAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,ST5,KIF14,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,AKT1,RIPK2,FZD4,CDCA2,CD40,MAP3K6,FZD7,IRS2,PPP2R5A,JAK1,STK26,WFS1,SLC27A1,NRG1,SPTBN5,EFNA5,ABCA1,NKX3-1,PINK1,SDC4,PSMD10,GDF15,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,GPLD1,BANK1,ACVRL1,FGFR2,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,LRRK1,CENPE,GPER1,FZD5 |
| 8.106e-05 | -9.42 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 1138 | 155 | 16441 | 1675 |
TXN,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,PDGFB,ERP29,CARD10,SPTB,GRM5,CALM2,PSMD1,CTGF,NPNT,SHC3,IL6ST,IL31RA,PIK3CA,DLG1,SLC39A10,RASGRP1,PLK1,PRKAR2B,CDK1,EDNRA,PLCG1,GPRC5B,ANKRD6,MADD,NOD2,PRKCDBP,CAB39,F2RL1,GAB1,PRKAA2,PIFO,ITGA6,RASA2,SOX9,CALM3,TEC,IGF1R,CYR61,MAP3K9,MDFIC,PIM1,MYDGF,NCAM1,WNT3A,CCDC88A,GPR161,MDFI,MMD,CALM1,PDE5A,STRADB,PSMA4,CDK5R1,RASA1,FAS,GNAS,MAPKAPK2,BCAR3,PRKAG2,SEMA4D,PELI2,PLPP3,CSF1,STK39,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,PRKACA,EMP2,STIL,PDGFA,CCND1,ST5,KIF14,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,AKT1,RIPK2,FZD4,CDCA2,CD40,MAP3K6,FZD7,IRS2,PPP2R5A,JAK1,STK26,WFS1,SLC27A1,NRG1,SPTBN5,EFNA5,ABCA1,NKX3-1,PINK1,SDC4,PSMD10,GDF15,TGFBR1,PKN1,FGF19,ADORA1,PTEN,BMP7,BAX,MAPK11,ERBB3,IQGAP3,SYK,SPRY2,PDGFC,RASGRF1,HES1,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,GPLD1,BANK1,ACVRL1,FGFR2,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,LRRK1,CENPE,GPER1,FZD5 |
| 8.136e-05 | -9.42 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 202 | 38 | 17758 | 1761 |
LTBP1,SPRED1,LMCD1,SLC1A3,PLXNA1,FAM198B,DNER,PHLDA1,TNFRSF19,PPP2R3A,RPS6KA2,ITGB8,VASN,ALDH1A3,FAM63A,ZNF365,FAM69A,GCNT1,C6orf1,RGMB,NR3C1,EIF5A2,AK4,LOXL2,GLT8D2,C3orf58,PLOD2,MAP2,MFSD2A,PEX2,MATN2,INPP4B,TLE1,NRG1,HMGA1,TANC2,MAFF,PKIA |
| 8.157e-05 | -9.41 | CERVERA_SDHB_TARGETS_1_UP | MSigDB lists | CERVERA_SDHB_TARGETS_1_UP | 112 | 25 | 17758 | 1761 |
SLC25A24,CCDC109B,PRSS23,UBASH3B,SH3BGRL,IL18,LOXL2,DUSP4,NEURL1B,KBTBD11,EMP2,TNFRSF19,TMEM54,HPSE,REEP1,NOD2,PGM2L1,RAB20,IGFBP2,PIK3CD,TANC2,PACSIN1,SGCB,S100A6,PCSK5 |
| 8.159e-05 | -9.41 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 578 | 86 | 17758 | 1761 |
PAPSS2,UGP2,CAST,CNOT8,FTH1,SLC7A2,SNN,SDC1,TMPRSS4,BTG3,CDH1,GRHL1,BCL6,PDE4D,TSPAN1,EGLN3,RAB27B,BTBD3,CPD,LAMP2,SH3BGRL,SYNE2,TNS1,LOXL2,SAV1,SOCS3,TAPBP,LRIG1,FAM110C,KLF5,KLF11,UNC5B,LTA4H,CAPN1,RRAGD,ZNF395,ENO2,HLA-E,HLA-F,AES,COL4A5,NCKAP1,SEPP1,NRP2,SLC25A36,MESDC2,ELF3,CXCL16,OTUD1,ADD3,ITGB8,PTEN,COL6A1,SORL1,ATP8B1,HLA-C,CITED2,IGSF3,PGM1,KCNJ12,GUSB,PPARA,LITAF,FBXO9,FNDC3A,NPHP3,FOS,FUCA1,HLA-B,CACHD1,SLCO4A1,SLC6A6,ETS2,PLOD2,TMC5,NR4A2,GRAMD1C,ZMIZ1,SERPINB1,AFAP1,AHR,CYBRD1,ZBTB33,ESYT2,EGLN1,XDH |
| 8.194e-05 | -9.41 | ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1) | protein interactions | 50807 | 28 | 11 | 16036 | 1726 |
PACSIN2,ARAP3,REPS2,TRIP10,RAB11FIP2,RAB11FIP1,CTTN,LRRK1,PACSIN1,ARF6,SH3KBP1 |
| 8.205e-05 | -9.41 | negative regulation of protein transport | biological process | GO:0051224 | 197 | 38 | 16441 | 1675 |
TXN,LGR4,NFKBIE,THRA,RAB23,PSMD10,SYTL4,BARD1,FBLN1,ERP29,APC2,WWP2,NEO1,NOV,SP100,BMP7,CABP1,UBE2J1,TMBIM6,DAB2IP,MDFIC,F2R,MDFI,CHP1,ERLEC1,ACVR1C,LITAF,RGCC,PTGER4,EZR,SNX12,BANK1,NFKBIA,RAB11FIP1,YOD1,NDFIP1,F2RL1,PKIA |
| 8.216e-05 | -9.41 | inositol lipid-mediated signaling | biological process | GO:0048017 | 142 | 30 | 16441 | 1675 |
TNRC6C,RHOA,AKT1,NR4A1,PIK3R1,CASP9,EZR,NRG2,ERBB2,AGO4,PHLPP1,PDGFB,CA8,FGF19,NCS1,PDGFA,IRS2,PLCH1,IGF1R,FGFR2,PTEN,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3C2B,PIK3CD,ERBB3,PLD1,GAB1 |
| 8.228e-05 | -9.41 | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | MSigDB lists | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | 416 | 66 | 17758 | 1761 |
LAMP1,SORBS1,UGP2,GNPDA1,ATP8A1,TMEM41B,LMCD1,TGOLN2,MORF4L2,SH3KBP1,ATP6V0B,HSF2,IFIT1,PDE4D,TECR,CLCN3,TIMP2,NFE2L1,MTRF1L,KIF1C,PPP1R14C,GTF2A2,H2AFV,DAG1,RHEB,ARF4,DPYSL3,MSL1,POPDC3,PEX2,MYL12B,RRAGD,CMAS,LGALS3,SCOC,PPP1R2,BVES,NCKAP1,TSPAN7,PPP2R3A,KIAA1161,KIF5B,ADD3,PTEN,SELK,HLA-C,SGCB,MRPS33,PSMB4,AMFR,MPP1,PIK3R1,PPARA,STRADB,NUBP1,NFIB,PSMA4,PLIN5,ENDOD1,SCARB2,TIMP3,TRIM69,UACA,NDFIP1,PKIA,RGMA |
| 8.230e-05 | -9.41 | purine ribonucleotide binding | molecular function | GO:0032555 | 1827 | 233 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,BVES,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,PDE5A,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,TMEM173,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,PDE4D,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RAB3B,RHOA,RAPGEF2,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 8.256e-05 | -9.40 | Signaling by ERBB4 | REACTOME pathways | R-HSA-1236394 | 312 | 55 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PHLPP1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,PTEN,SHC3,PIK3CA,DUSP10,CDKN1B,WWP1,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,NR4A1,ITCH,RAPGEF2,CALM1,PIK3R1,CASP9,GRIN1,AGO4,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,PHLPP2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1 |
| 8.258e-05 | -9.40 | REACTOME_HEMOSTASIS | MSigDB lists | REACTOME_HEMOSTASIS | 448 | 70 | 17758 | 1761 |
PLA2G4A,TP53,F11R,ITPR2,PDGFB,PRKACA,CALM2,PDGFA,WEE1,STIM1,PLCG2,PIK3CA,IRF2,F2R,RASGRP1,LAMP2,DOCK4,AKT1,PRKCQ,PRKAR2B,F12,ATP1B1,ITPR3,DOCK5,PLCG1,KCNMB4,PPP2R5A,HDAC1,IRF7,MAFF,CD63,HABP4,DGKQ,CALM3,SELL,KIF23,MERTK,SIRPA,KIF5B,GNB5,ITGA3,GATA2,KLC3,PRKG1,CD9,DGKG,SYK,RHOA,KIF20A,PLAUR,CALM1,PIK3R1,HMG20B,PDE5A,YES1,KIF11,BCAR1,GNA11,DGKE,RASGRP2,GNAS,DGKH,SERPINA1,PRCP,ARRB1,ITGAV,ATP1B3,L1CAM,EHD1,DOCK9 |
| 8.328e-05 | -9.39 | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDM_DN | 195 | 37 | 17758 | 1761 |
PLA2G4A,PKP2,DNAJB11,COL4A5,CD274,CNTNAP2,SDC1,PDGFB,MECOM,RPS6KA2,GATA2,ZFP36,FOSB,PIM1,TIPARP,SYK,RASGRP1,NCOA2,RIPK2,TNIP1,UBE2A,SPATA13,YES1,RNF19B,KIF11,TP53INP2,SNX12,JAK1,ETS2,SHROOM3,RND3,RELL1,FHL1,ICOSLG,ST3GAL1,CYBRD1,KLF7 |
| 8.328e-05 | -9.39 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | 195 | 37 | 17758 | 1761 |
RMND5A,CCNI,AVPI1,PAPSS2,EPAS1,GNPDA1,NUAK1,GGA1,CTDSPL,ABCG2,NDRG2,CRABP2,OAT,MERTK,BMP2K,RPS6KA2,RIMS3,COL6A1,PASK,FUT8,OPN3,CD9,TIAM1,NUP85,SLC16A5,RIMS2,PDGFC,MMD,ROR1,SESN1,FOS,RASA1,SWAP70,VSIG10,LTBP2,ZMIZ1,LTA4H |
| 8.386e-05 | -9.39 | MODULE_325 | MSigDB lists | MODULE_325 | 51 | 15 | 17758 | 1761 |
LAMP1,FADS2,NCOA3,HLF,CYP1A1,DLGAP5,SEMA4D,CDCA5,BDH1,AURKA,TFAP2C,TP53INP2,APPBP2,CYB5A,PRIM1 |
| 8.386e-05 | -9.39 | ISHIDA_E2F_TARGETS | MSigDB lists | ISHIDA_E2F_TARGETS | 51 | 15 | 17758 | 1761 |
TOP2A,CDKN2C,UBE2T,CDC20,PTTG1,NDC80,BUB1,NUSAP1,CCNB1,ANLN,CCNB2,CDK1,LBR,E2F8,PRIM1 |
| 8.386e-05 | -9.39 | CHIBA_RESPONSE_TO_TSA_UP | MSigDB lists | CHIBA_RESPONSE_TO_TSA_UP | 51 | 15 | 17758 | 1761 |
CDKN2C,TIMP2,TIMP3,ITGA3,CTGF,ITGA7,SIVA1,CASP9,FOSB,CD9,ARHGDIB,IGFBP2,TP53I11,FOS,HLA-A |
| 8.390e-05 | -9.39 | Band_41_domain | interpro domains | IPR019749 | 51 | 15 | 18293 | 1814 |
FRMPD3,EPB41L5,PLEKHH2,JAK1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,JAK3,MYLIP,FARP2,FRMD4B |
| 8.438e-05 | -9.38 | phospholipid transporter activity | molecular function | GO:0005548 | 50 | 15 | 16491 | 1673 |
PLSCR1,ATP9A,MFSD2A,ATP8A1,ANO6,ATP8B1,PITPNA,ATP8B3,ANO9,ANO4,PCTP,CPTP,ATP10D,ABCA1,ABCG1 |
| 8.493e-05 | -9.37 | GSE360_CTRL_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_DC_DN | 188 | 36 | 17758 | 1761 |
IL15RA,TRIP10,PSME2,TAP1,IL13RA1,NRP2,FANCI,B4GALNT1,DIRAS3,BTG3,GNB5,PAIP2B,TAGLN2,LAMP3,IFITM3,RAPGEF2,SAT1,PTGER4,AK4,GGH,DUSP4,SNTB1,IFIT3,CYB5A,SOCS3,CD83,SEMA4D,NFKBIA,MATN2,NR4A3,KLF11,TRAF5,ST3GAL1,COL16A1,IFI6,KLF7 |
| 8.493e-05 | -9.37 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 188 | 36 | 17758 | 1761 |
AVPI1,NFKBIE,LGR4,HEBP1,IL13RA1,TRIB2,HERC6,DNAH3,CARD10,LTBP3,RPS6KA2,FAM46A,CTGF,DACT1,RPL39,KLF3,TMBIM6,VAT1,TAGLN2,SMYD5,SULT2B1,MGAT5,NCOA2,ORAI2,MBP,ADCK3,DRAP1,NPC2,CDK5R1,BSDC1,CD83,MAN2A2,FHL1,FZD5,ST3GAL1,MAFF |
| 8.547e-05 | -9.37 | purine nucleotide binding | molecular function | GO:0017076 | 1837 | 234 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,BVES,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,AHCY,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,PDE5A,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,TMEM173,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,PDE4D,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RAB3B,RHOA,RAPGEF2,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 8.622e-05 | -9.36 | AACTGAC,MIR-223 | MSigDB lists | AACTGAC,MIR-223 | 93 | 22 | 17758 | 1761 |
SPRED1,PHF20L1,CDK17,SEPT6,UBE2A,ATP1B1,ALCAM,NFIB,TSPAN7,RASA1,IGF1R,RALGPS2,STIM1,CSNK1G1,IL6ST,DUSP10,STK39,PDE4D,TMEM64,WDR62,SCN3A,ATP2B1 |
| 8.628e-05 | -9.36 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 181 | 35 | 17758 | 1761 |
CCNE2,EPAS1,SDC4,MIER3,FAM102B,F11R,KCTD9,ZFYVE9,NRP2,DNAJB9,EPDR1,WDR44,ENPP5,TSPAN13,RAB27B,PTPRE,FAM69A,CTH,GFPT1,CLCN3,PHF20L1,HPS3,ERLEC1,CD55,ZNF84,SLC39A8,STAT4,SNTB1,C3orf58,FOXL1,SP4,NCOA3,SPINT2,NIPA1,RNF146 |
| 8.628e-05 | -9.36 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 181 | 35 | 17758 | 1761 |
CD99,FOXM1,VANGL1,MTL5,GPSM2,NUP62CL,BARD1,PSIP1,PTEN,KIF13B,KIF14,PLK4,GOT1,RFX5,MPHOSPH9,WBP5,SOCS5,CKS2,TIMP2,TACC1,CORO2A,MPP1,LYRM1,EZR,GGH,SLC11A2,LRRC1,IDH1,H2AFV,ADRBK2,DGKE,PGRMC1,DHTKD1,CENPE,NCAPG2 |
| 8.628e-05 | -9.36 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 146 | 30 | 17758 | 1761 |
DDX58,MX1,PRSS23,USP18,HERC5,GDF15,PRKAR2B,ISYNA1,IFIT3,HERC6,DHRS3,LTBP3,LGALS3BP,MECOM,SLC27A6,CDH1,ATP7B,HOXA9,AMMECR1,ABCB1,NR4A2,IRF7,HS3ST3B1,IFIT1,OAS3,RAB27B,F2R,IFIH1,GAD1,IFI6 |
| 8.738e-05 | -9.35 | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | MSigDB lists | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | 153 | 31 | 17758 | 1761 |
CENPA,ZWINT,SPC25,DLGAP5,ASPM,PTTG1,NDC80,CDCA8,NUF2,NANS,CCNB1,ANLN,H2AFV,KIF11,CENPN,CDK1,ARF4,TOP2A,UBE2T,PLOD2,ZNF367,CDCA5,RANBP1,NEK2,AURKA,BUB1,DONSON,NCAPG2,CCNB2,MELK,CKS2 |
| 8.780e-05 | -9.34 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | 167 | 33 | 17758 | 1761 |
FAM199X,DNAJC3,ITGA6,EPHA4,HABP4,ERBB2,SNN,TRIB2,DNAJB9,SCML1,MARCH8,OTUD1,AIM1,SGK1,PIM1,MARCH2,ZRANB1,MYLIP,TIPARP,C9orf72,KIFC2,SOCS3,IRS2,PELI2,BMP1,NFKBIZ,KLF11,NR4A2,EPB41L4A,ZNF502,TOB1,MAFF,PCSK5 |
| 8.838e-05 | -9.33 | negative regulation of cell adhesion | biological process | GO:0007162 | 219 | 41 | 16441 | 1675 |
CASP3,NF2,SERPINE2,LGALS3,UBASH3B,ERBB2,CD274,FBLN1,EPCAM,CDH1,PTEN,TBCD,BCL6,DLG1,PRKG1,ADAM15,FXYD5,TACSTD2,ERBB3,C10orf54,SOCS5,CYP1B1,EPB41L5,MFI2,FZD4,ITCH,PIK3R1,PPARA,RGCC,PDE5A,ARHGDIB,FZD7,RASA1,AP1AR,SWAP70,SEMA4D,ACVRL1,CORO1C,SPINT2,NDFIP1,JAK3 |
| 8.970e-05 | -9.32 | single-organism metabolic process | biological process | GO:0044710 | 4618 | 537 | 16441 | 1675 |
ACACB,MRPS15,AASS,AK7,SLC25A13,HEXB,RET,CACNA2D2,FBXO2,MMADHC,NRG2,IL18,MORF4L2,CA8,BARD1,CALM2,PSMD1,MUC4,UBE2T,CYP2S1,ALDH1A3,FUT1,CRY2,PIK3CD,ACOX2,TIPARP,MGAT5,APOBEC3G,CDA,MTRF1L,PRKAR2B,LOXL2,F12,ICMT,CYP4F3,ARF4,COL12A1,ENPP1,PLCG1,MID1IP1,NOD2,HDAC1,MRPS28,ITPKA,GAB1,ALDH6A1,SOX9,COX6C,ATG4A,GNS,ATP5H,RIMS3,FAM13B,PCYOX1,MAP3K9,ALPK1,NCAM1,NDUFA12,NUP85,PPP6R1,MCCC2,REC8,PQLC3,ERO1A,ELK1,NPHP3,PCTP,SPTLC2,PSMA4,CYB5A,NCOA3,SETD3,ITPR1,AURKA,MDH1,STK39,NUP58,XDH,EGLN1,MTM1,NQO1,PAPSS2,GALNT12,INPP5D,ACTR8,PTTG1,MGST2,PRKACA,CDS1,MUC16,SP100,XYLT2,ACSL4,DLG3,RASGEF1A,CDKN2D,ENPP4,SEC61B,COL6A2,RIPK2,SAT1,HTATIP2,XRCC6BP1,COX20,GABARAPL1,IRS2,ALDH3B1,WFS1,INPP4B,PNPLA6,TRABD2A,MAPK12,SDC4,OSGIN2,PDIA3,CTSZ,PKN1,PLPPR4,GSTP1,SGPL1,DTX3L,FUT2,ITGB8,SLC27A6,CTSC,ARSG,ALG13,MGAT4A,BAX,ECI2,ADAM15,MAPK11,CRTAP,PARP9,ACBD5,OPLAH,ADAMTS2,PLSCR1,RAPGEF2,PIK3R1,EIF5A2,ELOVL3,GRIN1,UBE2A,AK4,BLVRA,GALNT3,PLOD2,ACVRL1,DBI,NR4A3,ITGAV,HMGA1,CMPK2,WDR45B,CYBRD1,ACOT7,CUL4B,LMCD1,TEX2,ITPR2,MGAT5B,HDAC6,PDGFB,SDC1,SPTB,FANCI,RPS6KA2,SHC3,IL6ST,PAPSS1,SLC44A1,ABCA2,DUSP10,PLK1,CD55,NFE2L1,CR2,EZR,KLK6,PRKRA,IDH1,CDK1,KDM4D,PLCH1,HS6ST1,MSL1,AGPAT2,WIPI1,P4HA2,DOLPP1,PIK3C2B,PRKAA2,DNAJB2,RASA2,ASAH1,B4GALT4,DHRS3,FBLN1,B4GALNT1,MDFIC,AHCY,FAR2,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,MRPS33,MGAT4B,STRADB,EIF2AK1,PDK3,MAPKAPK2,COL13A1,PRPS2,P4HA3,FAM213A,PLD1,USP43,UGP2,FOXM1,P3H2,XYLT1,TMX4,TP53,ERBB2,SLC7A2,LPIN3,CYP26A1,RAD23A,PDGFA,PLCG2,SRR,VAT1,MINPP1,LMAN1,EGLN3,GM2A,CTH,SULF2,SIRT1,ERLEC1,AKT1,FIGNL1,PTGER4,ACO1,DNAJC10,DUOX1,ABHD12,ADAMTS14,C1orf43,AIFM3,ST3GAL1,LTA4H,NDST3,MAN2B2,COL9A3,CMAS,PINK1,HAL,BLVRB,GNE,SWI5,PSMD10,CRABP2,DSE,LBR,DNAJB9,ZDHHC21,UBE2J1,ALDH7A1,ABCD1,SYK,GCNT1,FAH,HMMR,PSMB4,GUSB,AMFR,PLAUR,PPARA,COL7A1,GGH,RNPEP,MAPK8IP1,DGKE,PRDX4,FUCA1,SERPINA1,SCG2,NAT1,PTGES,CFAP61,GAA,SLC35D2,TXN,HSPG2,PSME1,NANS,OAT,CCNB1,TYMP,CYP1A1,CTGF,IL31RA,AOX1,PIK3CA,SERINC2,KCNS3,STEAP2,SPATA18,ACVR1C,SLC35C1,AGO4,GALNT7,PIF1,MCFD2,SLC25A5,TP53I3,POR,PRIM1,SLC25A4,GDE1,GNPTAB,BMP1,PRDM5,DHTKD1,MRPL44,MRC2,TMEM55B,SLC25A27,NDUFA4,SLC1A3,ISYNA1,TNFRSF19,BDH1,PRKG1,SORL1,CACNA1D,PIKFYVE,TRAK2,GFPT1,FADS2,B3GNT7,PRODH,PMPCB,DDB2,ADCK3,LPGAT1,CALM1,PIP4K2C,NPC2,JADE2,GLT8D2,RASA1,MMP15,PRKAG2,FAAH,DCK,MAP3K5,PLA2G4A,SPRED1,SLC2A4,IQGAP1,RPS6KA1,FTH1,AIFM2,CYP39A1,APLP2,DOK4,DAB2IP,PDE4D,PHKA2,LGMN,SULT2B1,NAGA,GPX4,ATG4D,SEC23A,CYB5R2,PANK1,PRKCQ,SLC11A2,RAD17,ATP1B1,ITPR3,DDOST,JAK1,STK26,TRIOBP,SLC27A1,NRG1,HS3ST3B1,SLC27A3,APOBEC3H,CYB561,FBXO6,SPR,FGF19,PTEN,FUT8,CD9,SLC44A2,ATP8B1,ERBB3,OSGIN1,NCOA2,RASGRF1,B3GNT2,SHMT1,ALDH2,MPP1,FURIN,PARP4,C1GALT1C1,ARSK,FOS,CPTP,GPLD1,ACADSB,FGFR2,ABCB1,PGM2L1,GRIN2D,ARSB,SLC25A38,OCLN,NMRK1,UGT8,CRYM,CPT2,VARS2,CACNB4,CHPF,ABCD4,GRHL1,IMPAD1,DLG1,AKR1B1,TRPC1,TECR,RASGRP1,CYP1B1,MRPS36,ADRBK2,MAN2A2,NEIL1,HPSE,UEVLD,CAB39,ADIPOR1,GLA,NR2C2,FAM213B,PPP1R2,PYROXD2,ABCG2,CALM3,ADAMTSL4,B3GALNT1,CA2,COL6A1,NCEH1,GAD1,MDFI,OXR1,GYLTL1B,PDE5A,NUBP1,AMDHD1,STEAP1,GLCE,GNAS,FECH,ONECUT1,NUDT16,SLC6A6,UAP1,PLPP3,CDCA5,PITPNA,CTSA,YOD1,JAK3,COL16A1,APOL2,PSME2,HDAC11,PDIA5,COL18A1,SETDB2,CYP4F11,FABP6,RPN2,GOT1,CHP1,FRS3,MAP3K3,GLO1,DUSP4,FANCE,MAP3K6,JADE1,ALDH5A1,PEX2,SPTBN5,CYP2U1,ABCA1,GCLM,ENO2,CIT,COL4A5,TGFBR1,POMGNT1,HDAC9,TOP2A,ADRBK1,ADORA1,A4GALT,GALNS,IQGAP3,MYO5A,B3GALT6,PGM1,GCLC,OGDHL,RGCC,NADK2,LEPR,CTSL,SWAP70,PRCP,DHRS2,ARRB1,PLOD3,ABCG1 |
| 9.033e-05 | -9.31 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 300 | 51 | 17758 | 1761 |
TTC8,LTBP1,SPRED1,KIAA1462,SLC25A13,CTDSPL,PDIA5,SELL,TDRKH,KCTD12,PM20D2,TRIB2,SDC1,C11orf95,SGPL1,CCND1,RCN1,SUSD2,TNS3,RALGPS2,CTSC,TSPAN6,LMO4,IL31RA,SYK,SOCS5,SHMT1,MMD,NR3C1,SLC39A8,SEPT6,PDE5A,GGH,RUNX3,GALNT7,LHFPL2,CMTM7,MAN2A2,HLF,SLC25A4,AGPAT2,H1F0,HOXA9,ITPR1,NLRC5,ZNF704,CCDC69,EGFL7,HOOK1,ACOT7,DOCK9 |
| 9.093e-05 | -9.31 | glycoprotein biosynthetic process | biological process | GO:0009101 | 399 | 65 | 16441 | 1675 |
GALNT12,XYLT1,NANS,MGAT5B,PHLDA1,CHPF,MUC16,MUC4,XYLT2,FUT1,RPN2,LMAN1,TIPARP,MGAT5,SIRT1,SEC23A,TNIP1,GALNT7,MCFD2,ARF4,MAN2A2,HS6ST1,DDOST,DOLPP1,GNPTAB,HS3ST3B1,ST3GAL1,NDST3,CMAS,GNE,PDIA3,CTSZ,B4GALT4,POMGNT1,DSE,ADAMTSL4,B4GALNT1,B3GALNT1,FUT2,CTSC,MGAT4A,ALG13,A4GALT,FUT8,UBE2J1,PPP6R1,TRAK2,GCNT1,B3GALT6,GFPT1,CHSY3,B3GNT7,B3GNT2,MGAT4B,PARP4,GYLTL1B,C1GALT1C1,COL7A1,FOXL1,GLCE,FUCA1,GALNT3,SERPINA1,UAP1,CTSA |
| 9.240e-05 | -9.29 | neuron part | cellular component | GO:0097458 | 1197 | 159 | 17570 | 1756 |
LAMP1,EPHA4,RET,FBXO2,NDRG2,LYNX1,HDAC6,DNER,TMC1,GRM5,NCS1,SH3KBP1,PLS3,CALM2,IL6ST,CABP1,DPYSL2,DLG1,MYH14,CTTN,PACSIN1,MYRIP,ATL1,ORAI2,SGCE,SMARCA2,PRKAR2B,ARF4,DPYSL3,PIAS3,TRIM9,DNM1L,MAP2,KCNK1,PLK2,LIMK1,TMOD2,ITPKA,NRGN,LZTS1,LMTK3,SERPINE2,CALB2,SLC25A27,CALM3,SLC1A3,CNTNAP2,MERTK,DHRS3,ITGA3,CA2,IGF1R,SNX18,ZNRF2,RIMS3,FLRT3,KIF13B,KCNN4,EXOC8,AHCY,RIMS2,DPYSL5,CALM1,SCRIB,VEZT,ELK1,GNA11,NFIB,STX3,CDK5R1,FAS,RASGRP2,GNAS,PTPRF,GABRD,PHLPP2,S100A5,AURKA,ARPC2,SHROOM2,SEMA3A,TPRN,NF2,NQO1,IQGAP1,KCTD12,BCL2L1,PRKACA,NOV,SRR,DAB2IP,ESPN,GOT1,ACSL4,DLG3,SCN2A,DOCK4,CLCN3,TIMP2,MBP,S100A4,SEPT6,CCSAP,ITPR3,ALCAM,DAG1,GABARAPL1,ATP1A1,SLC9A6,WFS1,SIPA1L1,NRG1,SPTBN5,RGS14,COBL,BIN1,ANXA3,SORT1,PINK1,ENO2,CPEB4,LRP4,EPS8,GABRG2,KIF5B,ADD3,IGSF9,MLPH,GNB5,ADORA1,PTEN,CDK16,ANKS1B,CST3,KLC3,ATP8B1,MYO5A,DLGAP1,SYPL1,RASGRF1,RHOA,RAB3B,ZWINT,MPP1,RAPGEF2,GRIN1,STMN3,FOS,MAPK8IP1,CNTNAP1,SYT7,CTSV,ARRB1,GRIN2D,GPER1,CPEB2,L1CAM,ACOT7,SNPH |
| 9.297e-05 | -9.28 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 308 | 52 | 17758 | 1761 |
GRN,MYL9,ANXA3,LASP1,NF2,SERPINE2,TSC22D3,PTTG1,PSMD10,ASAH1,CRABP2,SLC20A1,DHRS3,GSTP1,DDR1,EMP2,LGALS3BP,CCND1,EPCAM,CDH1,TFAP2A,ANKRD12,TUBG1,KLF9,GM2A,CKS2,CYP1B1,FADS2,SMARCA2,PRSS23,TNIP1,MICB,SAT1,LITAF,TFAP2C,ITPR3,MYL12A,PSMA4,POR,RASA1,MDK,MMP15,TIMP3,DHRS2,PLK2,AXL,SETD3,AURKA,ARF6,UBE2C,LTA4H,HSPB1 |
| 9.303e-05 | -9.28 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | 196 | 37 | 17758 | 1761 |
PLA2G4A,ASAH1,KCTD12,FAM101B,SIRPA,IER3,CCND1,CA2,GATA2,CST3,TMEM51,CD9,SORL1,TAGLN2,PTPRE,S100A6,CKAP4,IGDCC4,ABCC1,STAU2,S100A4,MGAT4B,LITAF,GGH,DOCK5,PCTP,SPTLC2,RASGRP2,GABARAPL1,ATP13A2,PRCP,PTER,LRRK1,NRGN,SERPINB1,CPPED1,CD33 |
| 9.303e-05 | -9.28 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | 196 | 37 | 17758 | 1761 |
ARAP3,BLVRB,ASAH1,EFHD2,FAM198B,ARHGEF40,SIRPA,IER3,ARHGEF10L,APLP2,BCL6,SGK1,RAB20,MTMR11,ALDH3A2,CKAP4,CYP1B1,TGIF1,SAT1,BLVRA,DOCK5,CRISPLD2,TMEM164,ALDH3B1,HPSE,SERPINA1,ARRB1,ZDHHC7,KLF11,SERPINB6,EIF4EBP2,REEP4,LTA4H,AHR,CPPED1,PCSK5,CD33 |
| 9.303e-05 | -9.28 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | 196 | 37 | 17758 | 1761 |
SLC25A24,ARAP3,DDIT4L,MORC4,ASAH1,FAM101B,BMP2K,IER3,FAM111A,SNX18,METTL7A,PLCG2,FUT8,CD9,EPB41L4B,EGLN3,F2R,PTPRE,CKAP4,IGDCC4,SYPL1,ZWINT,PLSCR1,MGAT4B,PANK1,RNF19B,MAP3K6,NFIX,MAPKAPK2,IDE,PRKAG2,JAK1,CDCA7L,TLE1,LRRK1,CMPK2,SERPINB1 |
| 9.326e-05 | -9.28 | MODULE_464 | MSigDB lists | MODULE_464 | 13 | 7 | 17758 | 1761 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3,AOX1 |
| 9.344e-05 | -9.28 | V$FREAC2_01 | MSigDB lists | V$FREAC2_01 | 240 | 43 | 17758 | 1761 |
RMND5A,SLC2A4,CDKN1C,CHCHD7,THRA,ETV5,HABP4,DHX8,PHLPP1,SEPP1,DHRS3,ZNF385B,MECOM,CD109,TFAP4,FOXP2,WEE1,FRY,CALD1,IL6ST,LMO4,MITF,KLF3,CITED2,CLIP2,TIAM1,PLCB2,BCL9,RGAG1,ROR1,DUSP4,NFIB,NFIX,PITX2,KLF12,KBTBD2,AXL,PELI2,NRG1,C1orf43,MAFF,TOB1,EGLN1 |
| 9.397e-05 | -9.27 | platelet activation | biological process | GO:0030168 | 234 | 43 | 16441 | 1675 |
PLA2G4A,MYL9,CD63,DGKQ,HABP4,CALM3,ITPR2,PDGFB,MERTK,FZD6,PDGFA,CALM2,PLCG2,CD9,PIK3CA,WNT3A,F2R,DGKG,SYK,RASGRP1,LAMP2,RHOA,PLSCR1,AKT1,CALM1,PIK3R1,C1GALT1C1,PRKCQ,CD40,ITPR3,BCAR1,GNA11,MYL12A,DGKE,RASGRP2,DGKH,GNAS,SERPINA1,ABHD12,AXL,ITPR1,ARRB1,HSPB1 |
| 9.400e-05 | -9.27 | IRS-mediated signalling | REACTOME pathways | R-HSA-112399 | 277 | 50 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 9.425e-05 | -9.27 | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | 466 | 72 | 17758 | 1761 |
CASP3,GAA,SORBS1,NF2,SSH1,HDAC11,NDC80,TP53,TESK2,MRAS,BCL2L1,HDAC6,AIFM2,ARHGEF10L,TYMP,AP1M2,DLG1,TUBG1,ATG4D,SIRT1,CLCN3,COG2,EZR,NUSAP1,ARHGDIB,PIF1,ANLN,OPTN,MID1IP1,SLC25A4,DNM1L,LIMK1,PEX2,HDAC1,ARF6,ABCA1,FGD1,LASP1,WASF3,ARAP3,PACSIN2,PEX6,KIF23,SAC3D1,ATG4A,TOP2A,KIF5B,DOPEY2,KIF13B,PRKG1,BAX,ALS2CL,CCDC88A,REC8,SUN2,ZWINT,RHOA,NUBP1,KIF11,BCAR1,RASA1,RND3,CDCA5,FGD6,CENPE,HMGA1,NDE1,SHROOM2,ARSB,ESPL1,IFI6,GOLGB1 |
| 9.426e-05 | -9.27 | Pathways in cancer | KEGG pathways | hsa05200 | 397 | 68 | 6908 | 758 |
CCNE2,CASP3,EPAS1,RALBP1,RET,TP53,ERBB2,BCL2L1,PDGFB,PRKACA,APC2,PDGFA,CCND1,DAPK2,CDH1,PLCG2,MITF,PIK3CA,CDKN1B,PIK3CD,EGLN3,F2R,DVL2,RASGRP1,CKS2,AKT1,FZD4,CASP9,PTGER4,FZD7,EDNRA,PGF,PLCG1,JAK1,HDAC1,TRAF5,NKX3-1,ARHGEF11,ITGA6,COL4A5,TGFBR1,GSTP1,ETS1,FGF19,FZD6,MECOM,ITGA3,GNB5,IGF1R,PTEN,DAPK1,BAX,WNT3A,PLCB2,RHOA,PIK3R1,TCF7,FOS,GNA11,FAS,RASGRP2,GNAS,FGFR2,NFKBIA,ITGAV,PLD1,FZD5,EGLN1 |
| 9.479e-05 | -9.26 | protein kinase inhibitor activity | molecular function | GO:0004860 | 56 | 16 | 16491 | 1673 |
CASP3,SPRED1,CDKN1C,DNAJC3,PRKAR2B,TRIB2,MAPK8IP1,SOCS3,CDKN2C,PRKAG2,CDKN1B,HSPB1,CDKN2D,SPRY2,PKIA,CHP1 |
| 9.501e-05 | -9.26 | cellular response to peptide | biological process | GO:1901653 | 470 | 74 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,PSME2,NRG2,ERBB2,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,KLF3,PIK3CA,AKR1B1,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,PRKAR2B,POR,CASP4,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,NOD2,CAB39,EIF4EBP2,SPTBN5,NRG1,GAB1,RRAGD,PRKAA2,RASA2,PSMD10,CALM3,FGF19,HDAC9,IGF1R,ERBB3,NCAM1,MYO5A,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,NR4A3,NR4A2,GRIN2D,GPER1,TBC1D4,JAK3,CPEB2 |
| 9.509e-05 | -9.26 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 189 | 36 | 17758 | 1761 |
PLA2G4A,LAMP1,SORBS1,ARAP3,EPAS1,ETV5,ERI2,NDRG2,NDUFA4,MGST2,SNN,LMNA,M6PR,PSMD1,ITGA3,FRY,LMO4,MITF,DRAM1,DUSP10,RAB20,CKS2,METAP2,SOCS5,MCTP1,MCFD2,PCTP,IDH1,TIMP3,RPL12,H1F0,TCEAL4,PPM1H,TMEM14A,TBC1D4,ABCA1 |
| 9.509e-05 | -9.26 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | 189 | 36 | 17758 | 1761 |
DLGAP5,SLC25A13,PTTG1,ABCG2,CDCA8,LMCD1,KIF23,CCNB1,FANCI,IL17RB,C7orf49,COL6A1,BAX,PLK4,TPST1,SGCB,HMMR,SHMT1,ZWINT,KIF20A,CDC20,GGH,ARHGDIB,NUSAP1,KIF11,CDK1,GALNT3,SEMA4D,AGBL5,STK39,CCNB2,UBE2C,COBL,ESPL1,E2F8,MELK |
| 9.509e-05 | -9.26 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 189 | 36 | 17758 | 1761 |
DDX58,SLC25A24,ARHGEF3,UGP2,DLGAP5,ITGA6,NUF2,NCKAP1,VASH1,HMGXB4,SYTL2,TOP2A,FAM46A,SNX18,FAM13B,TRIM21,C2orf72,LGMN,F2R,TRAM1,SNX10,RASGRP1,NCOA2,FAM69A,ASPM,NUSAP1,ANLN,KIF11,ATP10D,PLEKHH2,IDE,RBL1,NR4A3,IRF7,RELL1,ESYT2 |
| 9.509e-05 | -9.26 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | 189 | 36 | 17758 | 1761 |
IL15RA,IL15,NLRX1,HLA-E,UBASH3B,ZCCHC24,DNAJB2,EPS8,SEPP1,PRRG4,TMEM63A,RCN1,RNF128,METTL7A,KIF13B,PIM1,MYLIP,PAQR7,ADCK3,CORO2A,SAT1,SERTAD3,TMEM151A,GGH,EPHA1,NPC2,YES1,SNTB1,PCTP,HLA-B,ENPP1,PTPRJ,RBM47,NR1D2,FBXO27,SERPINB1 |
| 9.509e-05 | -9.26 | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | 189 | 36 | 17758 | 1761 |
CTHRC1,SPC25,CDCA8,NENF,DAPK2,PQLC2,RPS6KA2,CDH1,GRHL1,PRICKLE3,KIF13B,OSBPL3,MITF,ENPP5,ABCA2,ALDH7A1,FARP2,HMMR,OPLAH,ASPM,STAU2,PCBP3,PANK1,IFIT3,PTGFRN,TCEAL8,STEAP1,FRMD4B,COL13A1,PHLPP2,WFS1,CMPK2,ARSB,CCNB2,UBE2C,RARG |
| 9.509e-05 | -9.26 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 189 | 36 | 17758 | 1761 |
GAA,MTM1,RUNX2,NLRX1,NDC80,SAMD9,CAMK1D,LBR,SNX18,CNPY3,PLCB2,APOBEC3G,XKR8,PHF20L1,TIMP2,TACC1,SH3BGRL,STK17B,CYP4F3,PLIN5,CRISPLD2,RASA1,KLHL2,GALNT3,TAPBP,CARHSP1,MSL1,PRCP,STK38,CAB39,ARRDC1,FAM117A,GRAMD1C,RELL1,ARPC2,CD33 |
| 9.517e-05 | -9.26 | adrenal_gland-extraadrenal-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-extraadrenal-pheochromocytoma | 4 | 4 | 17775 | 1757 |
GNAS,CDKN2C,PTEN,RET |
| 9.527e-05 | -9.26 | kidney development | biological process | GO:0001822 | 256 | 46 | 16441 | 1675 |
NKX3-1,CDKN1C,LGR4,THRA,IQGAP1,LRP4,RET,EPHA4,SOX9,SDC4,TGFBR1,OSR2,SDC1,PDGFB,SIX4,SGPL1,CTNNBIP1,EPCAM,CA2,ITGA3,NPNT,FRAS1,BMP7,DLG1,TFAP2A,BAX,AKR1B1,TACSTD2,NOTCH3,TIPARP,GCNT1,SULF2,HES1,FMN1,AMER1,PYGO1,NPHP3,FAT4,FGFR2,WFS1,OVOL1,GDF11,SOX8,OSR1,PCSK5,ADAMTS16 |
| 9.549e-05 | -9.26 | HALLMARK_ANDROGEN_RESPONSE | MSigDB lists | HALLMARK_ANDROGEN_RESPONSE | 100 | 23 | 17758 | 1761 |
NKX3-1,AKT1,SAT1,SEPP1,MERTK,CENPN,MYL12A,APPBP2,DNAJB9,CCND1,UAP1,H1F0,ALDH1A3,DBI,INPP4B,UBE2J1,SGK1,STK39,SPCS3,ITGAV,ZMIZ1,LMAN1,LIFR |
| 9.582e-05 | -9.25 | BASSO_CD40_SIGNALING_DN | MSigDB lists | BASSO_CD40_SIGNALING_DN | 63 | 17 | 17758 | 1761 |
ORAI2,IGFBP6,RAPGEF2,ARL4C,PRKAR2B,TRIB2,HDAC9,RASGRP2,ALDH5A1,METTL7A,RIMS3,BMP7,BCL6,UBE2J1,SYK,CTDSP2,GCNT1 |
| 9.616e-05 | -9.25 | DGKZ (diacylglycerol kinase, zeta) | protein interactions | 8525 | 24 | 10 | 16036 | 1726 |
SNTA1,PLCG1,RBL1,SNTB2,SAT1,PIK3CA,ARRB1,SNTB1,LEPR,RASGRP1 |
| 9.641e-05 | -9.25 | MHC_I_a_C | interpro domains | IPR010579 | 4 | 4 | 18293 | 1814 |
HLA-B,HLA-C,HLA-E,HLA-A |
| 9.682e-05 | -9.24 | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | 182 | 35 | 17758 | 1761 |
CASP3,PINK1,GRHL2,DAP,ETV5,DNAJB11,BCL2L1,TTYH3,IRF2BPL,TFAP4,FAM111A,TMEM87B,CST3,TFAP2A,VAT1,TECR,CTDSP2,TRIM8,HPS3,PQLC3,MFI2,OXR1,PLEKHO1,CBX6,FURIN,MCFD2,BBS2,MAN2A2,NUDT16,DUOX1,MMP17,PPM1H,MDH1,GLA,SNX30 |
| 9.686e-05 | -9.24 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | 75 | 19 | 17758 | 1761 |
SEC61B,LGALS3,IL15RA,ITGA6,HEXB,PDIA5,NUCB2,ARF4,PRDX4,DDOST,FUT8,RPN2,SERPINI1,MANF,CITED2,PDIA6,TRAM1,CKAP4,KDELR1 |
| 9.804e-05 | -9.23 | regulation of cytoskeleton organization | biological process | GO:0051493 | 400 | 65 | 16441 | 1675 |
GAS2L1,NF2,SSH1,ADD1,ARFGEF1,F11R,CCNB1,HDAC6,APC2,SPTB,PDGFA,CTGF,DLG1,PLK4,CDKN1B,ESPN,DIXDC1,TACSTD2,CTTN,NEB,PLK1,CAMSAP3,SSH3,CAPN6,PTGER4,EZR,PRKCQ,CCNF,MID1IP1,ARHGEF19,PLK2,LIMK1,TRIOBP,EFNA5,SPTBN5,TMOD2,ARF6,F2RL1,CKAP2,SDC4,EPS8,NCKAP1,TBCD,NEK2,WNT3A,CCDC88A,RHOA,FMN1,PIK3R1,RGCC,STMN3,EPHA1,BORA,KIF11,NUBP1,RASA1,CDK5R1,AP1AR,PLEKHH2,SWAP70,CTSV,AURKA,ARPC2,SHROOM2,AFAP1 |
| 9.938e-05 | -9.22 | macromolecule localization | biological process | GO:0033036 | 2012 | 254 | 16441 | 1675 |
SUN1,LAMP1,EXPH5,LTBP1,ACACB,UGT8,HSPG2,CPT2,ATP8A1,HEXB,ARFGEF1,TAP1,F11R,MPP5,SYTL4,HDAC6,NUP62CL,ERP29,ZFYVE16,RAB15,AP1M2,NPNT,OSBPL3,DLG1,ABCA2,SNX16,SUN3,RAB20,RP2,CTTN,TLN2,ANO4,PACSIN1,TRAM1,MYRIP,S100A13,PLK1,LAMP2,KCNIP3,CENPA,ACVR1C,EZR,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,CDK1,SPNS3,ARF4,OPTN,ENPP1,DNM1L,WIPI1,UEVLD,GNPTAB,RAB11FIP1,NOD2,ARF6,F2RL1,RRAGD,NXT2,PCSK5,PRKAA2,NFKBIE,GGA1,PEX6,SOX9,ETV5,RAB23,RAB6A,NCKAP1,CNTNAP2,FAM21C,LMNA,ATG4A,MESDC2,B4GALNT1,DOPEY2,SNX18,RINL,FRAS1,RPL39,KCNN4,KIF13B,EXOC8,SORL1,CADPS2,PIKFYVE,WNT3A,SYTL3,NUP85,RIMS2,SNX7,MDFI,KDELR1,TRAK2,PMPCB,KIF20A,ANO6,BTN3A2,STRADB,SCRIB,NPC2,ATP8B3,NUBP1,PCTP,PLIN5,STX3,GNAS,AP1AR,SCARB2,PRKAG2,TIMM8A,MFSD2A,TMEM30A,NFKBIA,SH3BP4,FAM83D,ZDHHC7,AURKA,PITPNA,CTSA,LTBP2,ATP1B3,SHROOM2,HOOK1,JAK3,TOB1,APOL2,NUP58,SNX30,EHD1,PLA2G4A,MTM1,ARMCX3,UPF3B,THRA,C5orf30,TP53,PKP2,MVB12B,EMP2,STIL,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,ATP6V0B,SVBP,ACAP2,CDH1,ZDHHC12,KIF14,REEP1,FABP6,BCL6,ZDHHC23,RPN2,IFIT1,ACSL4,LMAN1,RAB27B,DLG3,ARL4D,F2R,SNX10,GM2A,DVL2,CHP1,ATG4D,MYO5B,SEC23A,SEC61B,AKT1,COG2,FZD4,PTPRU,SYNE2,SLC11A2,ATP1B1,ERBB2IP,PYGO1,RAB38,SNX12,ATP10D,DAG1,DDOST,SHROOM3,CORO1C,PEX2,SLC27A1,ABCA1,TTC8,PINK1,PACSIN2,CD63,TSPAN15,ATP9A,FRMD6,LRP4,BTN3A1,PDIA3,PSMD10,ANO9,AIP,VPS26A,SIX4,SLC9A2,ZDHHC21,PDIA4,KIF5B,ADORA1,MLPH,SLC27A6,RNF128,BMP7,RRBP1,BAX,ATP8B1,PLEKHF1,ABCD1,SYK,MYO5A,NCOA2,SUN2,HES1,LCA5,FBLN5,RAB3B,CRB3,ZC3H11A,RAPGEF2,PIK3R1,EIF5A2,PPARA,PRICKLE1,NEURL1B,BBS2,CPTP,CNTNAP1,RPL12,MAMDC4,RAB11FIP2,SCG2,ARRB1,SPCS3,PLOD3,CEP41,WDR45B,RAB3IL1,ESYT2,ABCG1 |
| 9.947e-05 | -9.22 | condensed nuclear chromosome outer kinetochore | cellular component | GO:0000942 | 4 | 4 | 17570 | 1756 |
PLK1,BUB1,CCNB1,NDC80 |
| 1.003e-04 | -9.21 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13776 | 1423 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,LACTB2,DPP8,CMTM6,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,CRY2,TIAM1,TIPARP,MGAT5,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,MEGF8,ATP5H,RIMS3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,DGKG,NUP85,MCCC2,PAQR7,HPS3,PQLC3,ZNF503-AS2,ELK1,NPHP3,PCTP,SFXN5,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,ADAMTS16,DOCK9,NQO1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,ZNF365,MYT1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,XRCC6BP1,ZNF618,COX20,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,KLC3,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,AK4,CNTNAP1,RPL12,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,CMPK2,TLL2,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,ZNF367,ARRDC1,KLF11,RRAGD,RMND5A,PRSS8,PARP12,HJURP,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,SCRIB,PRX,RASGRP2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,STK38,EFNA5,IRF7,SYT13,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,GTF3A,GDF15,HMGN3,VPS26A,PARM1,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,ANKS6,ZNF823,STIM1,OSBPL3,KCNS3,PIK3CA,IRF2,SNX16,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,SERPINI1,WBSCR27,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TNFRSF19,PSIP1,MESDC2,DOPEY2,RALGPS2,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,MFSD3,SPRED1,FOXO6,TCTN2,DLGAP5,ST14,CCDC110,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,FZD7,POPDC3,TSPAN18,ZNF704,FAM195A,SLC27A3,COBL,CBX7,IER5L,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,DNAH3,EFNB1,FGF19,WWP2,SLC25A36,E2F7,TMEM87B,FUT8,FJX1,CD9,CCDC82,ERBB3,FARP2,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,GRTP1,ARSK,KIF11,CDK5RAP1,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,SIPA1L2,HSF2,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,ARHGDIB,MAN2A2,HPSE,KCNK1,MADD,ZNF165,NRGN,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,SLC12A2,CCDC88A,MDFI,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,RRBP1,ARVCF,CLIP2,C12orf75,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,DAPK2,WEE1,PSMD1,AP1M2,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,ARPC2,NDE1,DRP2,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ARL4D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,TIPRL,PDIA4,NEO1,DTX3L,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,GRIN1,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,NR1D2,ACVRL1,CENPE,HMGA1,USF2,DCBLD1,CYBRD1,UNKL,GNPDA1,FAM199X,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,LHFPL2,RHEB,OPTN,DPYSL3,PLCH1,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,BMF,ZCCHC24,UBASH3B,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,MAPKAPK2,COQ10A,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,FOXM1,XYLT1,CCDC68,ERBB2,FAM198B,LPIN3,CYP26A1,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,DUOX1,DNAJC10,PRRT4,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,SIRPA,PPP2R3A,SLC9A2,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,SLC20A1,NCS1,SESN3,ELMO2,RGS3,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,MTMR11,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,CCNF,SAV1,TP53I3,SPNS3,ARHGEF26,AHRR,RBM47,PLK2,PTER,GNPTAB,NKD1,DHTKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,TRIP10,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,CD274,MNS1,TMPRSS4,APLP2,ZNF75D,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,MYO5B,SEC23A,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,PCOLCE,ATP9A,CCNJL,SEPP1,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,NCOA2,OSGIN1,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,CCDC69,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CPT2,CAMKK1,HEBP1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,ZNF114,ARHGEF19,NEIL1,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,NCEH1,LRIF1,ALS2CL,OXR1,GYLTL1B,HMG20B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,CDCA5,RHOBTB2,ALPK3,PITPNA,EGFL7,KLF7,PROM2,SPC25,FAM92A1,IL15,MORC4,ARHGEF16,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,TWIST1,RPN2,F2R,PDIA6,SCYL3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,VSIG10,CYP2U1,REEP4,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,MIER3,NOTUM,TRMT2B,FAM167A,SAC3D1,IL17RB,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,MBNL3,LRRC66,OGDHL,KLHL2,HLA-B,C2orf70,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.025e-04 | -9.19 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 199 | 38 | 16441 | 1675 |
GCLM,PINK1,BMF,LGALS3,ITGA6,PSMD10,TGFBR1,BCL2L1,GSTP1,LMNA,IER3,DAPK1,BAX,TMBIM6,CTTN,FAIM,CDKN2D,CTH,SIRT1,PPIF,AKT1,FIGNL1,PLAUR,GCLC,STRADB,PELI3,SLC25A5,MAPK8IP1,G2E3,SCG2,WFS1,MADD,NRG1,NR4A2,ITGAV,UNC5B,HSPB1,IFI6 |
| 1.025e-04 | -9.19 | extrinsic component of membrane | cellular component | GO:0019898 | 254 | 45 | 17570 | 1756 |
PACSIN2,NF2,SERPINE2,ST14,IQGAP1,TEC,SYTL4,APC2,SYTL2,MUC16,CDH1,CDK16,SNX18,PIK3CA,SNX16,PIK3CD,EPB41L4B,TIAM1,MYLIP,SNX10,SYK,SYTL3,S100A6,SNX7,FARP2,EPB41L5,PLAUR,PIK3R1,EZR,YES1,GNA11,SNX12,GABARAPL1,GNAS,EPN3,NUCB1,JAK1,WIPI1,ARRB1,PIK3C2B,EPB41L4A,JAK3,WDR45B,SNX30,ESYT2 |
| 1.031e-04 | -9.18 | C2 | smart domains | SM00239 | 135 | 30 | 9131 | 997 |
PLA2G4A,MCTP1,CAPN6,ITCH,RASA2,SYTL4,PKN1,RASA1,SYTL2,ABR,WWP2,PLCG1,CPNE2,PLCH1,RAB11FIP2,SYT7,RGS3,RIMS3,PLCG2,PIK3CA,RAB11FIP1,DAB2IP,WWP1,CADPS2,PIK3C2B,SYT13,PLCB2,SYTL3,RIMS2,ESYT2 |
| 1.049e-04 | -9.16 | Growth_fac_rcpt_N_dom | interpro domains | IPR009030 | 127 | 27 | 18293 | 1814 |
LTBP1,FBLN5,IGFBP6,CELSR2,LRP4,FURIN,ERBB2,EPHA1,DNER,FBLN1,LTBP3,NOV,IGF1R,FAT4,CTGF,NPNT,CYR61,FRAS1,MATN2,BMP1,EGFL7,IGFBP2,ERBB3,EPHB4,LTBP2,NOTCH3,PCSK5 |
| 1.054e-04 | -9.16 | SCN5A (sodium channel, voltage gated, type V alpha subunit) | protein interactions | 6331 | 20 | 9 | 16036 | 1726 |
SNTA1,SCN5A,RGS3,SNTB2,CALM1,DLG1,SNTB1,DLG3,WWP2 |
| 1.056e-04 | -9.16 | KERLEY_RESPONSE_TO_CISPLATIN_UP | MSigDB lists | KERLEY_RESPONSE_TO_CISPLATIN_UP | 41 | 13 | 17758 | 1761 |
DDB2,PLK2,INPP5D,ALDH1A3,DRAM1,GDF15,ISYNA1,SESN1,EPS8L2,LMNA,FAS,STK17A,IER3 |
| 1.056e-04 | -9.16 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 41 | 13 | 17758 | 1761 |
LGR4,NR1D2,CKAP2,BCL6,SGK1,DUSP10,CTTN,DUSP4,LGMN,F2R,ZFAND5,SLC20A1,STK17B |
| 1.056e-04 | -9.16 | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | 41 | 13 | 17758 | 1761 |
CENPA,CSF1,STAT4,FXYD5,SELL,FAM102A,CR2,PBX3,ARRB1,FAM101B,GAD1,FGF19,CDK5R1 |
| 1.056e-04 | -9.16 | type 3 metabotropic glutamate receptor binding | molecular function | GO:0031800 | 4 | 4 | 16491 | 1673 |
CALM3,CALM2,CABP1,CALM1 |
| 1.063e-04 | -9.15 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 190 | 36 | 17758 | 1761 |
PINK1,ENO2,ATP9A,ATP8A1,SNN,OAT,KBTBD11,TTYH3,PLS3,FRY,KCNN4,ZFP36,FOSB,FUT8,TRPC1,TLN2,ATP2B1,MYO5B,SYPL1,ATL1,TIMP2,EZR,GLO1,DAG1,DPYSL3,CD83,ETS2,ANKRD6,MAP2,CDCA7L,MAL2,GEM,ZMIZ1,TANC2,PKIA,JARID2 |
| 1.063e-04 | -9.15 | GSE3982_DC_VS_TH1_UP | MSigDB lists | GSE3982_DC_VS_TH1_UP | 190 | 36 | 17758 | 1761 |
GAS2L1,PARP12,NFKBIE,LRRFIP2,IL18,MRAS,PLXNA1,MERTK,ARHGEF40,PARM1,NOV,FAM46A,DRAM1,BCL6,TACSTD2,ACOX2,TRAM1,CRTAP,MCCC2,PDGFC,CORO2A,SH3BGRL,PDE5A,BLVRA,NPC2,SESN1,ALCAM,CYB5A,RHEB,SCARB2,SLC9A6,SPINT2,FAM114A1,CLIP4,ARRB1,SLC27A3 |
| 1.063e-04 | -9.15 | GSE17721_POLYIC_VS_CPG_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDM_UP | 190 | 36 | 17758 | 1761 |
CCNI,TM2D2,INPP5D,IQGAP1,RASA2,PTTG1,CD274,MGST2,CAMK1D,LPIN3,SESN3,BDH1,KLF3,TPST1,BCL6,SORL1,SGK1,ESPN,RBMS2,CASP9,UTRN,SP4,ATP13A2,FUCA1,ENDOD1,HLA-B,TAPBP,PRCP,PLK2,SH3BP4,HDAC1,FZD5,NCAPG2,PRR15,CPPED1,ABCG1 |
| 1.063e-04 | -9.15 | GSE17721_LPS_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDM_UP | 190 | 36 | 17758 | 1761 |
IL15RA,IL15,LRP4,PDIA5,ARFGEF1,HMGN3,CACNB4,PSIP1,HMGXB4,EPS8L2,CPNE2,PTEN,FRYL,FAM20B,ABCA2,TPST1,CDKN1B,TRIM21,SELK,ECE1,SNX10,DDB2,AK4,ERBB2IP,IFIT3,CASP4,CD83,NCOA3,UAP1,PVRL2,TMEM30A,CSF1,HDAC1,GLCCI1,ISOC1,TMEM173 |
| 1.063e-04 | -9.15 | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | 190 | 36 | 17758 | 1761 |
SEMA6B,BCAM,FRMD6,HAL,MMADHC,OSGIN2,INTS8,NTAN1,PPP2R3A,BTG3,ST5,RPS6KA2,ELMO2,LLGL2,PRICKLE3,LMO4,CD70,MDFIC,HLA-C,CITED2,MYLIP,PTPRE,NCOA2,PLSCR1,SALL4,SYNE2,FURIN,CASP4,SOCS3,DHX32,ENDOD1,ETS2,KBTBD2,ANXA9,MAFF,EHD1 |
| 1.063e-04 | -9.15 | HOLLMANN_APOPTOSIS_VIA_CD40_UP | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_UP | 190 | 36 | 17758 | 1761 |
CD99,LTBP1,CCDC109B,TBC1D1,ATP8A1,C6orf106,GRK6,SBF1,CYP39A1,SS18,DPYSL2,ADCK2,MYBL1,SGCB,SNX10,PPP6R1,GM2A,CKAP4,SYPL1,ALDH2,SHMT1,MRPS33,TACC1,NR3C1,RUNX3,NUSAP1,RNF19B,NFIB,RHEB,ENDOD1,GNAS,SLCO4A1,ETS2,HDAC1,ARPC2,NRGN |
| 1.069e-04 | -9.14 | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | 576 | 85 | 17775 | 1757 |
MFSD3,SLC25A13,RPS6KA1,RET,TP53,ERBB2,GRK6,PRKACA,DDR1,SPTB,APPBP2,WEE1,MUC16,RPS6KA2,PQLC2,PAPSS1,DLG1,PIK3CA,SEMA3G,EPHB4,PIK3CD,DLG3,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,SMARCA2,AKT1,CAPN6,PBK,ATP1B1,PRKRA,MAP3K6,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MADD,PRKCDBP,PIK3C2B,KLF5,LIFR,HOXC13,MAPK12,PINK1,MRC2,CDK17,GNE,FAM134A,NEO1,IGF1R,CDK16,PTEN,MGAT4A,DAPK1,MAP3K9,SGK1,MAPK11,ERBB3,PIM1,PIKFYVE,SYK,SUN2,B3GNT2,ADCK3,PIK3R1,ZKSCAN2,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,MAPK8IP1,MAPKAPK2,FGFR2,DCK,AURKA,MAP3K5,TBC1D4,JAK3 |
| 1.071e-04 | -9.14 | PROTEIN_MODIFICATION_PROCESS | MSigDB lists | PROTEIN_MODIFICATION_PROCESS | 624 | 91 | 17758 | 1761 |
NF2,SSH1,HDAC11,RET,FBXO2,ERBB2,TESK2,HDAC6,CCND1,DAPK2,IL31RA,FUT1,PLK4,DUSP10,RPN2,PHKA2,F2R,PTPRE,SEPHS1,METAP2,MAP3K3,SIRT1,AKT1,PTPRU,COG2,PTPN9,GALNT7,LOXL2,DUSP4,ICMT,MAP3K6,STK17B,PTPRJ,DOLPP1,LIMK1,STK38,PCSK5,MAPK12,PRKAA2,CDK17,PINK1,TGFBR1,POMGNT1,TRIB2,SBF1,PKN1,MERTK,TSPAN7,PPP2R3A,RABGGTA,WWP2,B3GALNT1,IGF1R,FUT2,PTEN,CDK16,MGAT4A,FUT8,SGK3,MAP3K9,DAPK1,TPST1,PRKG1,SGK1,WWP1,PIM1,ERBB3,MYLIP,GAD1,CCDC88A,GCNT1,DDB2,AMFR,MGAT4B,PARP4,FURIN,STRADB,EIF2AK1,YES1,PRDX4,STK17A,MAPKAPK2,MMP15,PLOD2,ACVRL1,NR4A3,AURKA,PLOD3,UBE2C,JAK3,HIPK3 |
| 1.072e-04 | -9.14 | FERM_PH-like_C | interpro domains | IPR018980 | 26 | 10 | 18293 | 1814 |
EPB41L5,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,EPB41L4A,MYLIP,FRMD4B,FARP2 |
| 1.074e-04 | -9.14 | Innate Immune System | REACTOME pathways | R-HSA-168249 | 752 | 111 | 8202 | 867 |
SIGIRR,SPRED1,TXN,NLRX1,PSME2,RPS6KA1,IQGAP1,ERBB2,NRG2,PSME1,BCL2L1,ITPR2,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,ELMO2,SHC3,PLCG2,PIK3CA,CDKN1B,DUSP10,IRF2,DAB2IP,PIK3CD,LGMN,RASGEF1A,RASGRP1,FRS3,NLRP4,CD55,RIPK2,AKT1,ITCH,CASP9,PRKCQ,AGO4,PRKAR2B,DUSP4,ITPR3,CASP4,IRS2,PLCG1,JAK1,PPP2R5A,DDOST,LIMK1,NOD2,NRG1,SPTBN5,IRF7,GAB1,MAPK12,DDX58,WASF3,TNRC6C,LGALS3,HLA-E,RASA2,PSMD10,HERC5,CALM3,NCKAP1,TEC,PHLPP1,FGF19,ADRBK1,PTEN,TRIM21,MAPK11,ERBB3,HLA-C,NCAM1,CNPY3,SYK,MYO5A,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,PELI3,YES1,ELK1,FOS,PSMA4,RASA1,RASGRP2,MAPKAPK2,CTSL,HLA-B,FGFR2,PELI2,PHLPP2,NFKBIA,CTSV,ITPR1,NLRC5,DTX4,ARRB1,GRIN2D,PLD1,ARPC2,IFIH1,JAK3,TMEM173 |
| 1.075e-04 | -9.14 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 234 | 42 | 17758 | 1761 |
GCLM,NQO1,IL15,DNAJB2,INPP5D,BLVRB,GDF15,DHRS3,TNFSF9,LMNA,EPCAM,PSMD1,ZFP36,PHTF1,KIAA0319,CTH,LAMP3,MICB,SAT1,DUSP4,FOS,DGKE,FAS,GABARAPL1,STK17A,PGF,NUCB1,IDE,PDLIM3,MAP2,PLK2,P4HA2,ITGA7,LRIG1,GLA,GEM,TMEM159,F2RL1,HSPB1,COL16A1,MAFF,ABCG1 |
| 1.077e-04 | -9.14 | site of polarized growth | cellular component | GO:0030427 | 133 | 28 | 17570 | 1756 |
ORAI2,RASGRF1,TIMP2,IQGAP1,CALM1,EPS8,EPHA4,CALM3,STMN3,NDRG2,STX3,CDK5R1,DPYSL3,CALM2,ITGA3,FRY,SNX18,DPYSL2,FRYL,FLRT3,EXOC8,TMOD2,MYH14,CTTN,DLG3,COBL,L1CAM,MYO5A |
| 1.078e-04 | -9.14 | primary neural tube formation | biological process | GO:0014020 | 92 | 22 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 1.079e-04 | -9.13 | MHC_I_C | pfam domains | PF06623 | 4 | 4 | 16629 | 1696 |
HLA-B,HLA-C,HLA-E,HLA-A |
| 1.080e-04 | -9.13 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | 134 | 28 | 17758 | 1761 |
RHOA,AKT1,NR4A1,RPS6KA1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,DUSP4,PHLPP1,ITPR3,ELK1,PRKACA,CDK1,MAPKAPK2,IRS2,CALM2,PLCG1,RPS6KA2,ADRBK1,PTEN,SHC3,PIK3CA,CDKN1B,MAPK11,MAPK12 |
| 1.083e-04 | -9.13 | SASSON_RESPONSE_TO_FORSKOLIN_DN | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_DN | 88 | 21 | 17758 | 1761 |
LOC81691,CDKN1C,ATP9A,ARL4C,TP53,TP53I11,NPC2,DHRS3,CASP4,CARD10,STK17A,ARHGAP35,PTPRF,ITGA3,PDLIM3,AXL,DAPK1,SH3BP4,PIK3CD,GEM,PTPRE |
| 1.084e-04 | -9.13 | Tyr_kinase_cat_dom | interpro domains | IPR020635 | 88 | 21 | 18293 | 1814 |
EPHA4,RET,ERBB2,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,EPHA10,IGF1R,JAK1,FGFR2,AXL,PTK7,RYK,MAP3K9,EPHB4,ERBB3,JAK3,SYK |
| 1.085e-04 | -9.13 | V$HFH3_01 | MSigDB lists | V$HFH3_01 | 183 | 35 | 17758 | 1761 |
RUNX2,REPS2,CPEB4,CHCHD7,ETV5,SCML1,FOXP2,ITGA3,ARTN,CYR61,WDR44,VASN,FUT8,SLC44A1,SGK1,TWIST1,NCAM1,CYP26B1,SMARCA2,SSH3,SLC39A8,RGAG1,PRX,NIN,KLF12,COL13A1,NKD1,NR4A3,ADAMTS14,C1orf43,REEP4,TOB1,NR3C2,KLF7,RGMA |
| 1.085e-04 | -9.13 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | 183 | 35 | 17758 | 1761 |
LZTFL1,LGALS3,EPAS1,CAST,EFHD2,CYB561,FAM198B,DSE,S100A2,SLC20A1,PHLDA1,LMNA,CTSC,ENPP5,RASGEF1A,FAR2,MYBL1,APOBEC3G,MMD,S100A4,MPP1,ATP1B1,STX3,ONECUT1,HLF,WIPI1,PRCP,ABCB1,PLEKHG1,FAM110C,PLOD3,RARG,AHR,TMEM173,RGMA |
| 1.085e-04 | -9.13 | GSE25087_TREG_VS_TCONV_ADULT_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_UP | 183 | 35 | 17758 | 1761 |
SLC25A24,SSH1,IQGAP1,SDC4,BARD1,PLS3,PIK3AP1,ANKS1B,SLC16A6,IQGAP3,MYBL1,TIPARP,CRTAP,MCCC2,ABCC1,GCNT1,CORO2A,S100A4,SNTB2,UTRN,ATP1B1,GLCE,GABARAPL1,OPTN,FRMD4B,PIAS3,IRS2,CDK19,RBL1,RAB11FIP1,NR4A2,TRAF5,GLCCI1,AHR,SNX30 |
| 1.090e-04 | -9.12 | MARTINEZ_RB1_AND_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 558 | 83 | 17758 | 1761 |
LTBP1,TRIM2,KLK10,FAM92A1,ST14,CRYM,THRA,DNAJC3,FHDC1,PKP2,COL18A1,DDR1,CCND1,APLP2,GRHL1,SIVA1,FRYL,ZFP36,ALDH1A3,SLC44A1,ABCA2,CDH3,RPN2,ECE1,MYH14,TECR,SCARA3,PTPRE,PLK1,CLCN3,MBP,COL6A2,CENPA,CELSR2,CAPN6,USP18,SNTB2,PANK1,KIF1C,GLO1,ITPR3,FZD7,OVOL1,AGFG2,TMOD2,UNC5B,CD99,LASP1,COL9A3,PCOLCE,CDKN1C,HJURP,ESRP1,SOX9,RAB6A,GSTP1,TNFRSF19,EFNB1,FZD6,NEO1,TMCC3,CTNNBIP1,DOPEY2,CALD1,ATP5H,IGFBP2,IGDCC4,NFE2L3,SHMT1,GCLC,ELOVL3,MYBL2,NFIB,FRMD4B,PTPRF,TIMP3,PVRL2,PLOD2,CLIP4,LTBP2,MAP3K5,RARG,SNX30 |
| 1.090e-04 | -9.12 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 452 | 70 | 17758 | 1761 |
LMO7,TRIM2,MPP5,VASH1,SPTB,NCS1,PLS3,RPS6KA2,DACT1,REEP1,TLN2,MYT1,CYP1B1,SEC23A,PRKAR2B,ANLN,SESN1,DAG1,NIN,HLF,KLF12,MAP2,PLK2,CORO1C,CAB39,FGD1,CDK17,DCAF7,ZCCHC24,LRP4,EPS8,ETV5,PM20D2,INTS8,SBF1,ETS1,PSIP1,NRP2,CDK16,GATA2,BHLHE41,KLF9,CITED2,PIKFYVE,CLIP2,NCOA2,IGSF3,AMOTL2,RHOA,MMD,NR3C1,AMFR,OXR1,PDIK1L,RANBP9,LEPR,SLC6A6,FGFR2,RND3,HNRNPH2,RAP2C,ITPR1,FHL1,GEM,CEP41,TOB1,OCLN,PKIA,NIPA1,EGLN1 |
| 1.103e-04 | -9.11 | GSE2706_UNSTIM_VS_8H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_UP | 176 | 34 | 17758 | 1761 |
MAN2B2,SIGIRR,AVPI1,HSPG2,ZCCHC24,BLVRB,XYLT1,NUCB2,ERP29,MNS1,SLC16A6,SIVA1,FXYD5,ALDH7A1,TPCN1,CRTAP,CYP1B1,DDB2,MBP,SLC35C1,PDK3,PTGFRN,SCRN2,NUDT16,DUOX1,WFS1,P4HA2,CDCA7L,CLMN,PIK3C2B,FHL1,PLD1,MAP3K5,CBX7 |
| 1.103e-04 | -9.11 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | 176 | 34 | 17758 | 1761 |
DDX58,IL15RA,TAP1,HERC5,SAMD9,CD274,HERC6,LGALS3BP,DTX3L,FAM46A,SP100,TRANK1,ELMO2,TRIM21,IFIT1,OAS3,ETV7,APOBEC3G,PARP9,MX1,AMOTL2,PLSCR1,USP18,MICB,IFIT3,TRIM69,SEMA4D,C19orf66,SECTM1,NLRC5,IRF7,CMPK2,IFIH1,IFI6 |
| 1.122e-04 | -9.10 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | 101 | 23 | 17758 | 1761 |
CPD,CASP3,SSH1,HOXB7,TBC1D1,MGAT4B,ARL4C,IL18,TNS1,PLXNA1,CCNB1,GNA11,LGALS3BP,SAC3D1,FAS,CCND1,ETS2,GATA2,TRIM21,IFIT1,ATP1B3,UBE2C,F2R |
| 1.124e-04 | -9.09 | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | MSigDB lists | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | 155 | 31 | 17758 | 1761 |
LAMP2,BIN1,MX1,RASGRF1,UGT8,CDKN1C,PIK3R1,PPFIBP2,LITAF,UBE2A,PRKCQ,KLK6,COL4A5,RNF19B,PPP2R3A,FRMD4B,TMEM63A,SS18,SCARB2,GPRC5B,FGFR2,KIF13B,LMO4,ABCA2,TMBIM6,WWP1,CDK18,ERBB3,GLA,TIAM1,COL16A1 |
| 1.124e-04 | -9.09 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 155 | 31 | 17758 | 1761 |
TIMP2,ZNF395,PRSS23,EPAS1,MPP1,EPHA4,CDA,TNS1,COL7A1,BLVRA,DUSP4,DSE,DHRS3,SCML1,IER3,DAPK2,SLCO4A1,CYP1A1,HPSE,SLC16A6,RGS3,NOD2,CD9,NRG1,MAFF,PTGES,ABCA1,GM2A,ABCG1,RRAGD,CYP1B1 |
| 1.128e-04 | -9.09 | CUI_TCF21_TARGETS_UP | MSigDB lists | CUI_TCF21_TARGETS_UP | 36 | 12 | 17758 | 1761 |
MDK,HMMR,COL6A2,HJURP,EPHA4,HDAC11,COL6A1,CDKN1B,IGFBP2,NCAM1,LHFPL2,IGDCC4 |
| 1.128e-04 | -9.09 | CELL_MATRIX_ADHESION | MSigDB lists | CELL_MATRIX_ADHESION | 36 | 12 | 17758 | 1761 |
SGCE,SORBS1,FBLN5,ITGA3,NF2,PTEN,ACVRL1,COL13A1,ITGA7,TESK2,ADAM15,RASA1 |
| 1.131e-04 | -9.09 | regulation of JNK cascade | biological process | GO:0046328 | 158 | 32 | 16441 | 1675 |
PINK1,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,CTGF,IGF1R,DACT1,MAP3K9,DUSP10,DAB2IP,MDFIC,SYK,RASGRP1,DVL2,MDFI,AKT1,RIPK2,FZD4,ITCH,MAP3K6,FZD7,MAPK8IP1,ANKRD6,NOD2,MAP3K5,FZD5,F2RL1,HIPK3,GAB1 |
| 1.147e-04 | -9.07 | regulation of dendrite development | biological process | GO:0050773 | 105 | 24 | 16441 | 1675 |
GRN,FOXO6,RHOA,CIT,RAPGEF2,CDC20,EPHA4,GRIN1,CAMK1D,CDK5R1,PTEN,SEMA4D,BHLHB9,BMP7,PLK2,SIPA1L1,KIAA0319,DAB2IP,NRG1,PACSIN1,ARF6,ITPKA,LZTS1,COBL |
| 1.148e-04 | -9.07 | ISSAEVA_MLL2_TARGETS | MSigDB lists | ISSAEVA_MLL2_TARGETS | 58 | 16 | 17758 | 1761 |
COL9A3,IGFBP6,IL18,LOXL2,ALCAM,ELF3,HDAC9,HPSE,AXL,CD9,PRKCDBP,FHL1,TAGLN2,SLC16A5,L1CAM,SEMA3B |
| 1.151e-04 | -9.07 | TTTGTAG,MIR-520D | MSigDB lists | TTTGTAG,MIR-520D | 326 | 54 | 17758 | 1761 |
SCN5A,ADD1,TCTN2,CPEB4,DDIT4L,ETV5,PDCL,SLC1A3,CNTNAP2,PHLPP1,ETS1,ZNF385B,CCND1,MDM1,LLGL2,BHLHE41,DAPK1,TPST1,PDE4D,PIKFYVE,NCAM1,CITED2,LRP11,TRAM1,GAD1,BTBD3,TIPARP,SCN3A,ATP2B1,KDELR1,IGDCC4,SULF2,SOCS5,SIRT1,HES1,KIF11,STK17B,SP4,BSDC1,DCP2,DHX32,ANKRD10,RBM47,KLF12,KCNK1,PCDH19,ARRDC1,ADIPOR1,KLF11,NDFIP1,CPEB2,MAFF,ABCA1,CMTM4 |
| 1.183e-04 | -9.04 | positive regulation of cellular component movement | biological process | GO:0051272 | 387 | 63 | 16441 | 1675 |
SEMA6B,ANXA3,LGALS3,ATP8A1,SOX9,RET,COL18A1,SELL,TGFBR1,CD274,CAMK1D,HDAC6,PDGFB,ETS1,FBLN1,SRPX2,NRP2,HDAC9,PDGFA,EPCAM,DAPK2,CXCL16,ITGA3,IGF1R,CYR61,MEGF8,BCL6,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,EPB41L5,DOCK4,SUN2,RHOA,AKT1,RAPGEF2,PIK3R1,ANO6,SYNE2,FURIN,EPHA1,BCAR1,DOCK5,GPLD1,IRS2,PLCG1,ONECUT1,SWAP70,SEMA4D,PLPP3,CSF1,FAM110C,ITGAV,GPER1,CFAP20,F2RL1,SEMA3A,HSPB1 |
| 1.186e-04 | -9.04 | MODULE_493 | MSigDB lists | MODULE_493 | 64 | 17 | 17758 | 1761 |
LTBP1,C6orf1,TRIP10,EPHA4,CTDSPL,ST5,TIMP3,MITF,PPM1H,DRAM1,CNNM4,ZMIZ1,NDE1,MYLIP,CLIP2,AFAP1,SOCS5 |
| 1.207e-04 | -9.02 | ERBB2 (erb-b2 receptor tyrosine kinase 2) | protein interactions | 2064 | 144 | 31 | 16036 | 1726 |
NF2,SH3BGRL,CD82,PIK3R1,ERBB2,TEC,ERBB2IP,HDAC6,MAPK8IP1,HLA-A,RASA1,ELF3,BCAR3,PLCG1,TNS3,NCOA3,IGF1R,MUC4,JAK1,ANKS1B,SHC3,IL6ST,DOK4,PLCG2,LRIG1,PIK3C2B,NRG1,ERBB3,SYK,TOB1,FRS3 |
| 1.208e-04 | -9.02 | Tyr_kinase_AS | interpro domains | IPR008266 | 95 | 22 | 18293 | 1814 |
LMTK3,TESK1,EPHA4,RET,ERBB2,TESK2,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,IGF1R,JAK1,FGFR2,AXL,PTK7,RYK,PLK4,EPHB4,JAK3,SYK |
| 1.208e-04 | -9.02 | LABBE_WNT3A_TARGETS_UP | MSigDB lists | LABBE_WNT3A_TARGETS_UP | 108 | 24 | 17758 | 1761 |
AMOTL2,FADS2,IFIT3,PDGFB,ALCAM,CDK1,TSPAN7,GPLD1,PRIM1,GNAS,TOP2A,CCND1,ADD3,CA2,CTGF,CYR61,NGFRAP1,CTSC,DCK,SIVA1,SGK1,AURKA,CCNB2,AHR |
| 1.215e-04 | -9.02 | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | 184 | 35 | 17758 | 1761 |
SORT1,REPS2,ASAH1,EFHD2,CTSZ,TMEM170B,GSTP1,ADAMTSL4,TTYH3,BMP2K,HDAC9,APLP2,DPYSL2,DRAM1,CD9,RP2,MTMR11,NCEH1,PTPRE,CLIP2,DGKG,CCDC88A,PDGFC,MCTP1,PRKAR2B,PCTP,NUDT16,PRCP,SECTM1,ZDHHC7,GLA,LTA4H,ARSB,CPPED1,STARD3NL |
| 1.215e-04 | -9.02 | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | 184 | 35 | 17758 | 1761 |
ARHGEF3,CDK17,TTC39B,CAST,ITGA6,ETS1,ADD3,KLF3,RUNDC3B,ANKRD12,MDFIC,TMEM64,CNOT6L,CITED2,LRIF1,ATP2B1,FAM69A,B3GNT2,ELK3,NR3C1,STAT4,PIK3R1,HEATR5A,SESN1,DCTN6,NCOA3,CDK19,LRIG1,INPP4B,NFKBIZ,MAP3K5,F2RL1,GLCCI1,LTA4H,JARID2 |
| 1.216e-04 | -9.01 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | molecular function | GO:0016903 | 46 | 14 | 16491 | 1673 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH1A3,OGDHL,AOX1,AKR1B1,DHTKD1,ALDH7A1,FAR2,MRPS36,ALDH3A2,XDH |
| 1.221e-04 | -9.01 | BIOPOLYMER_MODIFICATION | MSigDB lists | BIOPOLYMER_MODIFICATION | 643 | 93 | 17758 | 1761 |
NF2,SSH1,HDAC11,RET,FBXO2,ERBB2,TESK2,HDAC6,CCND1,DAPK2,IL31RA,FUT1,PLK4,DUSP10,RPN2,PHKA2,F2R,PTPRE,APOBEC3G,SEPHS1,METAP2,MAP3K3,SIRT1,AKT1,PTPRU,COG2,PTPN9,GALNT7,LOXL2,DUSP4,ICMT,MAP3K6,STK17B,PTPRJ,DOLPP1,LIMK1,STK38,PCSK5,MAPK12,PRKAA2,CDK17,PINK1,TGFBR1,POMGNT1,TRIB2,SBF1,PKN1,MERTK,TSPAN7,PPP2R3A,RABGGTA,WWP2,B3GALNT1,IGF1R,FUT2,PTEN,CDK16,MGAT4A,FUT8,SGK3,MAP3K9,DAPK1,TPST1,PRKG1,SGK1,WWP1,PIM1,ERBB3,MYLIP,GAD1,CCDC88A,GCNT1,DDB2,AMFR,MGAT4B,PARP4,FURIN,STRADB,EIF2AK1,YES1,FOS,PRDX4,STK17A,MAPKAPK2,MMP15,PLOD2,ACVRL1,NR4A3,AURKA,PLOD3,UBE2C,JAK3,HIPK3 |
| 1.224e-04 | -9.01 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1785 | 227 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RHOA,RAB3B,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 1.225e-04 | -9.01 | ENZYME_REGULATOR_ACTIVITY | MSigDB lists | ENZYME_REGULATOR_ACTIVITY | 319 | 53 | 17758 | 1761 |
ARHGEF3,ARAP3,PPP1R2,CDKN1C,ARHGEF11,IQGAP1,DNAJC3,RALBP1,RASA2,RGS20,ARFGEF1,PPP2R3A,ARHGEF10L,CDKN2C,CARD8,RGS3,CABP1,RANBP1,CST3,CDKN1B,TWIST1,CDKN2D,TIAM1,FARP2,DOCK4,TIMP2,RAPGEF2,CASP9,PIK3R1,PRKAR2B,ARHGDIB,PRKRA,RASA1,MAPK8IP1,ABR,CDK5R1,SOCS3,MMP15,PPP2R5A,MMP17,MADD,SPINT2,FGD6,ARRB1,SERPINI1,CTSA,SERPINB6,MAP3K5,RGS14,RAP1GAP,AIFM3,PKIA,FGD1 |
| 1.235e-04 | -9.00 | KOHOUTEK_CCNT1_TARGETS | MSigDB lists | KOHOUTEK_CCNT1_TARGETS | 47 | 14 | 17758 | 1761 |
CXCL16,PTER,ENPP5,ARL4C,BMP1,STMN3,FAM102A,CLDN4,TACSTD2,COL7A1,TINAGL1,DNER,BBS2,S100A13 |
| 1.235e-04 | -9.00 | PID_IL6_7_PATHWAY | MSigDB lists | PID_IL6_7_PATHWAY | 47 | 14 | 17758 | 1761 |
PIAS3,JAK1,AKT1,LMO4,IL6ST,MITF,PIK3R1,PIK3CA,MAPK11,BCL2L1,PTPRE,FOS,GAB1,SOCS3 |
| 1.236e-04 | -9.00 | mucopolysaccharide metabolic process | biological process | GO:1903510 | 125 | 27 | 16441 | 1675 |
HMMR,CHSY3,B3GALT6,SLC35D2,B3GNT7,B3GNT2,HSPG2,AKT1,GUSB,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,CHPF,GLCE,GNS,IMPAD1,XYLT2,GALNS,PIM1,ARSB,ST3GAL1,NDST3,CHP1 |
| 1.237e-04 | -9.00 | V$SP1_Q6_01 | MSigDB lists | V$SP1_Q6_01 | 228 | 41 | 17758 | 1761 |
LASP1,UGP2,PPM1J,IQGAP1,CALM3,TIPRL,EPS8L2,CALM2,APLP2,LLGL2,FOSB,SERINC2,ANKRD12,CNNM4,ADAM15,TAGLN2,ECE1,NOTCH3,ABCC1,CPD,ACBD5,CYP26B1,SHMT1,DRAP1,LYRM1,CALM1,PDIK1L,MAP3K6,CDK5R1,PIAS3,PGF,DUOX1,PVRL2,CORO1C,AGBL5,PGM2L1,PITPNA,KLF5,KLF11,C1orf43,HOXC13 |
| 1.237e-04 | -9.00 | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | 177 | 34 | 17758 | 1761 |
TNRC6C,DLGAP5,FOXM1,CKAP2,KIF23,HMGN3,CCNB1,PTEN,KIF14,FAM13B,PLK4,SLC44A2,PLEKHF1,LGMN,RASGEF1A,CKS2,PHF20L1,ASPM,CDC20,CDCA2,PIF1,ANLN,KIF11,BORA,CDK1,DPYSL3,MDK,ATP1A1,HMGA1,NDE1,FZD5,CCNB2,MELK,GOLGB1 |
| 1.237e-04 | -9.00 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | 177 | 34 | 17758 | 1761 |
GCLM,TXN,GNPDA1,PHLDA1,ZFYVE16,EFR3A,SGK1,SELK,RAB20,EGLN3,PTPRE,SPRY2,OSGIN1,WBP5,CKS2,TGIF1,LONRF3,MFI2,NR3C1,NR4A1,PLAUR,COQ10B,DUSP4,RHEB,STX3,SLCO4A1,PRKAG2,ETS2,CSF1,NR4A2,GLA,GEM,RRAGD,ESYT2 |
| 1.238e-04 | -9.00 | YTATTTTNR_V$MEF2_02 | MSigDB lists | YTATTTTNR_V$MEF2_02 | 660 | 95 | 17758 | 1761 |
SLC2A4,SPC25,TRIP10,VANGL1,CAST,DNAJC3,MORC4,SPTB,ZNF385B,CCND1,PDGFA,HSF2,CTGF,ARHGEF37,NPNT,DACT1,KLF3,FOSB,MITF,BCL6,DUSP10,TWIST1,RAB20,PHKA2,SMARCA2,TIMP2,CITED4,PANK1,PRKAR2B,KIF13A,ZFAND5,SP4,NFIX,DZIP1L,ENPP1,KCNMB4,KLF12,WIPI1,SIPA1L1,ADAMTS14,KLF5,C1orf43,LIFR,NR3C2,IER5L,PRKAA2,CTHRC1,FRMD4A,SCOC,DNAJB2,PBX3,ETS1,ANO1,PPP2R3A,SIRPA,NRP2,LMNA,SCML1,HDAC9,FOXP2,ANKS1B,FLRT3,BMP7,TFAP2A,NEK2,NCAM1,SGCB,RIMS2,CRTAP,WBP5,TRAK2,SNX7,C9orf9,RASGRF1,HES1,PHF20L1,ARAP2,NR4A1,PPARA,STRADB,VEZT,FOS,NFIB,MUM1L1,GPLD1,GNAS,SEMA4D,ITGA7,AMMECR1,RAP2C,GRIN2D,CTSA,MAL2,HIPK3,RNF146 |
| 1.243e-04 | -8.99 | Insulin receptor signalling cascade | REACTOME pathways | R-HSA-74751 | 280 | 50 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 1.246e-04 | -8.99 | Hemostasis | REACTOME pathways | R-HSA-109582 | 515 | 81 | 8202 | 867 |
PLA2G4A,INPP5D,TP53,F11R,ITPR2,PDGFB,PRKACA,CALM2,PDGFA,WEE1,STIM1,PLCG2,PIK3CA,IRF2,PIK3CD,F2R,RASGRP1,LAMP2,DOCK4,AKT1,PRKCQ,PRKAR2B,F12,ATP1B1,ITPR3,DOCK5,PLCG1,KCNMB4,JAK1,PPP2R5A,ABHD12,HDAC1,SERPINB6,IRF7,MAFF,SERPINE2,CD63,ITGA6,DGKQ,HABP4,KIF23,CALM3,SELL,MERTK,SIRPA,KIF5B,ITGA3,GNB5,GATA2,KLC3,PRKG1,CD9,DGKG,SYK,ATP2B1,RHOA,KIF20A,PLAUR,CALM1,PIK3R1,HMG20B,PDE5A,YES1,KIF11,BCAR1,GNA11,DGKE,RASGRP2,GNAS,DGKH,SERPINA1,PRCP,ITPR1,ARRB1,ITGAV,CENPE,ATP1B3,JAK3,L1CAM,EHD1,DOCK9 |
| 1.256e-04 | -8.98 | steroid hormone mediated signaling pathway | biological process | GO:0043401 | 57 | 16 | 16441 | 1675 |
THRB,NKX3-1,NR3C1,NR4A1,THRA,PPARA,NR1D2,BMP7,NR4A3,NR4A2,GPER1,NR2C1,RARG,NR3C2,PAQR7,NR2C2 |
| 1.267e-04 | -8.97 | activation of MAPKK activity | biological process | GO:0000186 | 237 | 43 | 16441 | 1675 |
SPRED1,PSME2,RASA2,CALM3,NRG2,ERBB2,PSMD10,TGFBR1,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADORA1,SHC3,MAP3K9,DAB2IP,ERBB3,NCAM1,RASGEF1A,F2R,RASGRP1,FRS3,MAP3K3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,PSMA4,MAP3K6,RASA1,IRS2,PLCG1,JAK1,FGFR2,NRG1,SPTBN5,GRIN2D,MAP3K5,JAK3 |
| 1.269e-04 | -8.97 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 149 | 30 | 17758 | 1761 |
SUN1,SIRT1,BCAM,PARP12,PPP1R2,FZD4,PTPN9,MGAT4B,SAT1,NFE2L1,MPP5,ETS1,DDR1,VPS26A,FZD6,PRX,APPBP2,M6PR,HLF,RBM47,CTGF,KLF12,PVRL2,WDR44,TSPAN6,FLRT3,CDCA7L,PDE4D,NCOA2,RGMA |
| 1.272e-04 | -8.97 | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | 156 | 31 | 17758 | 1761 |
GRN,MX1,PLSCR1,ARHGEF11,S100A11,IFITM3,USP18,CALM1,ETV5,HERC5,CALM3,IFIT3,HERC6,RNF19B,LGALS3BP,HLA-A,SIRPA,CALM2,GNAS,NUCB1,MID1IP1,HPSE,H1F0,CDK16,NMI,ABCD1,TAGLN2,IFIT1,OAS3,IFI6,KDELR1 |
| 1.285e-04 | -8.96 | Cytokine Signaling in Immune system | REACTOME pathways | R-HSA-1280215 | 539 | 84 | 8202 | 867 |
SPRED1,TRIM2,PSME2,IQGAP1,INPP5D,ERBB2,NRG2,IL18,PSME1,PDGFB,PRKACA,TRIM68,SPTB,CALM2,PDGFA,PSMD1,SP100,SHC3,IL6ST,PIK3CA,DUSP10,IRF2,DAB2IP,IFIT1,PIK3CD,OAS3,RASGEF1A,RASGRP1,FRS3,MAP3K3,MX1,TRIM8,RIPK2,USP18,DUSP4,CD40,SOCS3,IRS2,PLCG1,JAK1,PPP2R5A,NOD2,NRG1,SPTBN5,IRF7,DDX58,HLA-E,RASA2,HLA-F,HERC5,CALM3,PSMD10,TEC,FGF19,HLA-A,TRIM21,CD70,TNFRSF12A,ERBB3,HLA-C,NCAM1,TRIM62,NUP85,SYK,RASGRF1,PSMB4,IFITM3,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,PELI3,IFIT3,PSMA4,RASA1,HLA-B,FGFR2,PELI2,ARRB1,GRIN2D,JAK3,NUP58,IFI6 |
| 1.295e-04 | -8.95 | glycosaminoglycan metabolic process | biological process | GO:0030203 | 166 | 33 | 16441 | 1675 |
SLC35D2,PAPSS2,HSPG2,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,CHPF,GNS,IMPAD1,XYLT2,PAPSS1,GALNS,PIM1,CHP1,B3GALT6,CHSY3,HMMR,B3GNT7,B3GNT2,AKT1,GUSB,GLCE,FUCA1,HS6ST1,HPSE,HS3ST3B1,ARSB,ST3GAL1,NDST3 |
| 1.305e-04 | -8.94 | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | 351 | 57 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,TP53,ARFGEF1,PDIA3,SYTL4,BCL2L1,BARD1,ERP29,ZFYVE9,APPBP2,PDIA4,M6PR,ATG4A,KIF5B,ZFYVE16,DOPEY2,AP1M2,CARD8,CDH1,KIF13B,STEAP2,ABCA2,BCL6,TINAGL1,ARL4D,LMAN1,F2R,TRAM1,KDELR1,MDFI,ATG4D,SUN2,ZWINT,AKT1,COG2,HTATIP2,STRADB,KIF1C,NUSAP1,NPC2,ICMT,OPTN,KLHL2,KCNMB4,SCG2,CDCA5,NOD2,CTSA,LTBP2,CENPE,ARSB,SHROOM2,NRBP1,ABCA1,ABCG1 |
| 1.315e-04 | -8.94 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | 102 | 23 | 17758 | 1761 |
ENPP4,TRIM2,SERTAD4,TMX4,FAM102B,PRKAR2B,C3orf58,SP4,ARHGEF26,MECOM,ALDH5A1,ABHD12,METTL7A,TSPAN6,LMO4,PASK,ZNF704,FAM117A,SLC27A1,CNPY3,TRAF5,MYLIP,GLCCI1 |
| 1.317e-04 | -8.93 | regulation of cell development | biological process | GO:0060284 | 793 | 113 | 16441 | 1675 |
EMX1,FOXO6,NF2,SSH1,EPHA4,RET,TP53,PLXNA1,CAMK1D,FAM101B,GRM5,NCS1,IL6ST,KIF14,DPYSL2,BCL6,DUSP10,DAB2IP,TWIST1,TACSTD2,DIXDC1,SEMA3G,NOTCH3,CTTN,PACSIN1,TIAM1,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,SAV1,CDK1,DAG1,RHEB,ARHGAP35,DPYSL3,GPRC5B,BHLHB9,PLK2,CORO1C,PTK7,LIMK1,SIPA1L1,TRIOBP,EFNA5,NRG1,ITPKA,ARF6,RGS14,LZTS1,COBL,GRN,BIN1,SEMA6B,SERPINE2,ADGRG1,CIT,SOX9,LRP4,ETV5,TGFBR1,CRABP2,FAM21C,FBLN1,TEAD3,HDAC9,ITGA3,PTEN,GATA2,MEGF8,BMP7,MYCL,VASN,KIF13B,KIAA0319,BAX,SORL1,TNFRSF12A,WNT3A,TRIM62,CCDC88A,TLE6,RIMS2,EPB41L5,HES1,TGIF1,RHOA,MMD,MFI2,ASPM,RAPGEF2,GRIN1,RGCC,HMG20B,PDE5A,CDK5R1,CDK5RAP1,PTPRF,NCOA3,AP1AR,SEMA4D,TMEM30A,CSF1,AURKA,GPER1,GDF11,ARPC2,SOX8,ARSB,SEMA3A,L1CAM |
| 1.318e-04 | -8.93 | nucleoside binding | molecular function | GO:0001882 | 1805 | 229 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,CDA,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADORA1,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RHOA,RAB3B,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 1.319e-04 | -8.93 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | 471 | 72 | 17758 | 1761 |
CASP3,TRIP10,BROX,CD82,NRG2,IL18,BCL2L1,SNN,EMP2,PDGFB,TNFSF9,CARD10,KREMEN1,IER3,NKAIN3,RTKN2,ARL4D,NEB,PLK1,SPEF2,CD55,RIPK2,FZD4,PIF1,RNF19B,FZD7,DPYSL3,KLF12,BHLHB9,KLF5,HS3ST3B1,COBL,PRR15,MAFF,NKX3-1,GOLIM4,SDC4,HAL,ZDHHC21,FOXP2,TNS3,ITGB8,DRAM1,MDFIC,MAPK11,ABCD1,PIKFYVE,DGKG,ATP2B1,IGSF3,BTNL9,FMN1,RAPGEF2,PLAUR,MRS2,LITAF,TP53INP2,CD83,GABRD,CSF1,MFSD2A,NFKBIA,SLC2A6,AGBL5,OTUB2,PLD1,GEM,DRP2,ICOSLG,HIPK3,TLL2,EHD1 |
| 1.325e-04 | -8.93 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | 192 | 36 | 17758 | 1761 |
CHCHD7,ATP8A1,FHDC1,C6orf106,TEX2,CAMK1D,GPSM2,APOBEC3B,ELMO2,N4BP3,MITF,TBCD,CDH3,PHKA2,PLCB2,TPCN1,CTDSP2,STAT4,SAT1,PDK3,RNF19B,IDH1,HLA-B,RBM47,PRCP,NAT1,CDCA5,SECTM1,HDAC1,IRF7,RGS14,NCAPG2,IFIH1,PRR15,CBX7,ABCG1 |
| 1.325e-04 | -8.93 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 192 | 36 | 17758 | 1761 |
RMND5A,FRMD6,DAP,KIF23,C6orf106,MGST2,FAM101B,LGALS3BP,TOP2A,RPS6KA2,RALGPS2,IL6ST,TSPAN13,MINPP1,RCAN3,CDKN2D,MX1,MPP1,PLAUR,CBX6,EZR,PDK3,SESN1,CYB5A,NFIX,RASGRP2,ATP1A1,PPP2R5A,TWSG1,ACVRL1,PRPS2,NR4A3,IRF7,NFKBIZ,ST3GAL1,EHD1 |
| 1.325e-04 | -8.93 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_UP | 192 | 36 | 17758 | 1761 |
CASP3,KLK10,TXN,NFKBIE,SERPINE2,PSME2,SDC4,PSME1,CD274,KREMEN1,LGALS3BP,DOPEY2,CYP1A1,SH3BP1,FUT8,CST3,SGK1,TAGLN2,NOTCH3,HMG20B,PDK3,ASB13,RNPEP,SP4,ENDOD1,SCARB2,UAP1,NR1D2,PLK2,TMEM30A,GNPTAB,NFKBIA,ABCB1,NR4A2,CPEB2,NRBP1 |
| 1.325e-04 | -8.93 | - | gene3d domains | 1.20.80.10 | 49 | 15 | 9988 | 1080 |
EPB41L5,ACBD5,PLEKHH2,FRMD4A,NF2,FRMD6,DBI,ECI2,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 1.337e-04 | -8.92 | organelle localization | biological process | GO:0051640 | 412 | 66 | 16441 | 1675 |
MTM1,DLGAP5,NDC80,SYTL4,CCNB1,HDAC6,SYTL2,AP1M2,KIF14,DPYSL2,DLG1,PIK3CD,LMAN1,RAB27B,PACSIN1,S100A13,RASGRP1,MYO5B,SEC23A,CENPA,SYNE2,EZR,KIF13A,NUSAP1,MCFD2,NIN,TRIM9,WIPI1,SYT13,GRN,CDCA8,CTSZ,GPSM2,KIF5B,GATA2,LLGL2,CTSC,PPP6R1,SPRY2,SYTL3,MYO5A,SUN2,RAB3B,TACC1,ASPM,COL7A1,SCRIB,BBS2,NUBP1,STX3,PLIN5,AP1AR,SERPINA1,SYT7,PVRL2,FGFR2,CDCA5,FAM83D,NR4A3,AURKA,CENPE,GEM,NDE1,SHROOM2,ESPL1,SNPH |
| 1.338e-04 | -8.92 | ARHGEF10L (Rho guanine nucleotide exchange factor 10 like) | protein interactions | 55160 | 4 | 4 | 16036 | 1726 |
ANXA9,SCN2A,NR4A1,DRAP1 |
| 1.339e-04 | -8.92 | - | gene3d domains | 1.10.238.10 | 260 | 48 | 9988 | 1080 |
MYL9,SLC25A24,REPS2,S100A11,SLC25A13,CALB2,CALM3,EFHD2,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,PLS3,CALM2,RCN1,CABP1,PLCB2,DGKG,S100A13,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,STAT4,S100A4,CALM1,UTRN,AIF1L,MCFD2,MYL12A,NIN,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,CGREF1,NKD1,S100A5,EFCAB14,PPP2R3C,DRP2,CAPN1,EHD1 |
| 1.343e-04 | -8.92 | endocytosis | biological process | GO:0006897 | 491 | 76 | 16441 | 1675 |
ILDR1,TRIP10,RALBP1,FTH1,ITPR2,BCL2L1,DNER,TMPRSS4,ZFYVE9,SH3KBP1,SUSD2,ELMO2,DPYSL2,PLCG2,STEAP2,PIK3CA,RAB20,TINAGL1,CTTN,MARCH2,SCARA3,PACSIN1,SNX10,XKR8,CLCN3,EZR,LOXL2,ITPR3,SNX12,ADRBK2,ENPP1,PLCG1,DNM1L,CORO1C,LIMK1,AXL,ABCA1,GRN,BIN1,ANXA3,MRC2,PACSIN2,SORT1,ATP9A,LRP4,NCKAP1,MERTK,LGALS3BP,M6PR,CXCL16,ADRBK1,ADORA1,SNX18,GATA2,RINL,CD9,SORL1,PIKFYVE,SYK,C9orf72,SNX7,PIK3R1,SCRIB,EIF2AK1,YES1,NEURL1B,MAPKAPK2,CSNK1G1,ITPR1,SH3BP4,ARRB1,ITGAV,ARPC2,SNX30,ESYT2,EHD1 |
| 1.352e-04 | -8.91 | phosphatidylinositol-mediated signaling | biological process | GO:0048015 | 139 | 29 | 16441 | 1675 |
TNRC6C,RHOA,AKT1,NR4A1,PIK3R1,CASP9,EZR,NRG2,ERBB2,AGO4,PHLPP1,PDGFB,CA8,FGF19,NCS1,PDGFA,IRS2,PLCH1,IGF1R,FGFR2,PTEN,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3C2B,PIK3CD,ERBB3,GAB1 |
| 1.357e-04 | -8.91 | FERM_C | pfam domains | PF09380 | 26 | 10 | 16629 | 1696 |
EPB41L5,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,EPB41L4A,MYLIP,FRMD4B,FARP2 |
| 1.358e-04 | -8.90 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | MSigDB lists | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 83 | 20 | 17758 | 1761 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,TIMP2,FURIN,COL4A5,COL7A1,COL12A1,MMP15,COL13A1,PLOD2,MMP17,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 1.361e-04 | -8.90 | TACGGGT,MIR-99A,MIR-100,MIR-99B | MSigDB lists | TACGGGT,MIR-99A,MIR-100,MIR-99B | 22 | 9 | 17758 | 1761 |
CYP26B1,AP1AR,CTDSPL,SLC44A1,HS3ST3B1,TRIB2,ICMT,EPDR1,RAVER2 |
| 1.362e-04 | -8.90 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2630 | 313 | 17775 | 1757 |
AASS,AK7,ATP8A1,DNAJC3,CACNA2D2,PPFIBP2,FBXO2,PLXNA1,LACTB2,VASH1,ZNF275,SLC9A7,CDKN2C,CYP2S1,AOX1,PIK3CA,ATRNL1,CRY2,MGAT5,ERAP2,TNIP1,SH3BGRL,CDA,SLC35C1,PRKAR2B,TNS1,LOXL2,GALNT7,LDB2,AHRR,ATP7B,PRDM5,AGFG2,MRPS28,WBSCR27,GAB1,DDX58,MRC2,FRMD4A,TBC1D1,SLC25A27,SLC1A3,GPSM2,TTYH3,ELF3,FRY,FAM189A1,AIM1,PRKG1,SORL1,CADPS2,OSTF1,ALPK1,CACNA1D,NCAM1,MYLIP,ULBP2,C9orf72,MCCC2,GFPT1,DDB2,KLK5,SLC37A1,KIF20A,TBC1D8B,SALL4,AMER1,NPHP3,ANTXR1,PCTP,SFXN5,PSMA4,GNA11,NFIB,DCP2,CYB5A,PTPRF,DGKH,CACHD1,SLCO4A1,GABRD,PELI2,DCK,ITPR1,PCDH19,CABIN1,PLIN3,HOOK1,RNF224,TCTN2,ST14,RGS20,C5orf30,PKP2,REPS1,ZNF385B,APOBEC3B,MUC16,CDH1,LRP11,MYO5B,FOXJ2,SYNE2,UTRN,TMEM144,PRKCQ,XRCC6BP1,ITPR3,ALCAM,CMTM7,SHROOM3,SLC27A1,NRG1,SLC27A3,NR3C2,COBL,ARHGEF3,EPS8,BTN3A1,PBX3,CYB561,DNAH3,ITGB8,IGSF9,RNF128,ANKS1B,CALD1,MGAT4A,FUT8,SGK3,PLEKHF1,NCOA2,FARP2,PARP9,PVRL4,ADAMTS2,PDGFC,LCA5,ARAP2,FAM160A1,RAPGEF2,PIK3R1,CXorf57,FURIN,DIAPH2,YES1,SNTB1,ACADSB,PLOD2,ACVRL1,RAB11FIP2,CSTF2,ITGAV,WDR62,CYBRD1,MELK,TMEM131,ESYT2,JARID2,LTBP1,UGT8,FAM199X,CUL4B,EPHA4,FHDC1,ARFGEF1,NDC80,ITPR2,DNER,KREMEN1,SPTB,TMC1,SH3KBP1,PLS3,NKAIN3,HSF2,NPNT,TSPAN6,DPYSL2,PAPSS1,ANKFN1,SLC44A1,DLG1,POF1B,NTN4,MYH14,SLC39A10,TECR,ANO4,MYRIP,NEB,LAMP3,ZNF462,THRB,MCTP1,ITCH,CR2,ROR1,PRKRA,IDH1,SESN1,PTGFRN,RHEB,EDNRA,HS6ST1,KCNMB4,KLF12,EPB41L4A,CAPN1,GRN,PARP12,UBASH3B,CNTNAP2,FAM81A,PHLPP1,FBLN1,DHRS3,AIM1L,TNS3,DAZAP1,CA2,IGF1R,FRAS1,LIMCH1,GAD1,MPHOSPH9,ALS2CL,CKAP4,SNX7,CHSY3,PODXL2,PLEKHA6,CORO2A,ZNF320,HEATR5A,RASGRP2,BCAR3,CSF1,LTBP2,ZDBF2,SHROOM2,SEMA3A,RARG,SNX30,LMO7,NCKAP5,TMX4,TP53,PDIA5,COL18A1,CYP26A1,KCTD9,TTC21B,EFR3A,WDR44,EPB41L4B,NOTCH3,OAS3,TMTC1,MBP,C3orf52,ACO1,DOCK5,DNAJC10,PTPRJ,RBL1,ABHD12,PTK7,TLE1,EFNA5,LIFR,CMAS,GOLIM4,ARHGEF11,POC1B,GABRG2,SELL,HMGN3,POMGNT1,LBR,FZD6,NRP2,SLC9A2,PPP2R3A,ZDHHC21,MLPH,LLGL2,BMP7,LYPD6,KIAA0319,UBE2J1,KLF9,MYO5A,HMMR,DLGAP1,RAB3B,NR3C1,CRB3,ASPM,AMFR,PPARA,LRRC66,TTC7A,MAML2,DGKE,KLHL2,HLA-B,BANK1,SWAP70,TWSG1,OTUB2,PLOD3,ZMIZ1 |
| 1.366e-04 | -8.90 | RUTELLA_RESPONSE_TO_HGF_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_DN | 229 | 41 | 17758 | 1761 |
CCNI,SIGIRR,ZNF395,CDKN1C,HLA-E,TMX4,PDIA5,SELL,IL13RA1,GTF3A,ARHGEF40,TSEN34,HDAC9,APLP2,DPYSL2,ZFP36,SORL1,EGLN3,CNPY3,SLC16A5,CD55,PLSCR1,RUNX3,SPTLC2,ZFAND5,MAP3K6,STK17B,RASGRP2,CD83,MAN2A2,ETS2,SPINT2,RAB11FIP1,CCDC69,NRG1,NR4A2,LRRK1,NDE1,F2RL1,LTA4H,TRAF5 |
| 1.367e-04 | -8.90 | cellular response to insulin stimulus | biological process | GO:0032869 | 358 | 59 | 16441 | 1675 |
PRKAA2,SPRED1,SORBS1,SLC2A4,PSME2,RASA2,CALM3,NRG2,ERBB2,PSMD10,PSME1,PDGFB,SPTB,FGF19,HDAC9,CALM2,PDGFA,ATP6V0B,PSMD1,IGF1R,SHC3,PIK3CA,DAB2IP,GOT1,ERBB3,NCAM1,RASGEF1A,MYO5A,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,STRADB,BCAR1,PSMA4,RHEB,RASA1,GPLD1,IRS2,ENPP1,PRKAG2,IDE,JAK1,FGFR2,CAB39,EIF4EBP2,GRIN2D,NRG1,SPTBN5,JAK3,TBC1D4,CPEB2,GAB1,RRAGD |
| 1.367e-04 | -8.90 | V$CEBP_Q2_01 | MSigDB lists | V$CEBP_Q2_01 | 259 | 45 | 17758 | 1761 |
PLA2G4A,NCKAP5,SPRED1,TM2D2,CDKN1C,HOXB7,THRA,ETV5,TESK2,MPP5,DENND2D,ANO1,SIRPA,NRP2,NEO1,WEE1,PTEN,CYR61,CALD1,LMO4,LHX6,MITF,BCL6,PRKG1,TMBIM6,PDE4D,PLCB2,MAP3K3,ADAMTS2,CITED4,MOSPD2,LONRF3,PCTP,SPTLC2,SNX12,NFIX,XKRX,PITX2,KLF12,KLF5,NFKBIZ,CEP41,ARF6,TOB1,XDH |
| 1.379e-04 | -8.89 | Interleukin-2 signaling | REACTOME pathways | R-HSA-451927 | 245 | 45 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,INPP5D,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,JAK1,PPP2R5A,FGFR2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 1.387e-04 | -8.88 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | 178 | 34 | 17758 | 1761 |
DDX58,CCDC109B,IL15RA,ARHGEF11,TAP1,HERC5,SAMD9,OSR2,HERC6,LGALS3BP,DTX3L,FAM111A,CYP1A1,SP100,OAS3,ALPK1,ETV7,APOBEC3G,PARP9,MX1,PLSCR1,USP18,IFIT3,PSMA4,FAS,TRIM69,PVRL2,C19orf66,SECTM1,NFKBIZ,IRF7,CMPK2,IFIH1,IFI6 |
| 1.387e-04 | -8.88 | ATF2_UP.V1_DN | MSigDB lists | ATF2_UP.V1_DN | 178 | 34 | 17758 | 1761 |
PLA2G4A,ARHGEF3,MRPL44,GALNT12,PKP2,KCTD12,FAM198B,HOXB2,DENND2D,ZNF432,FRY,ADAM15,LIMCH1,IGFBP2,PIM1,ERAP2,CTH,CYP1B1,SLC39A8,AK4,ROR1,FOS,NFIB,EDNRA,IRS2,SLCO4A1,PDLIM3,GPRC5B,PTER,PELI2,SPINT2,RAB11FIP1,PER3,CYBRD1 |
| 1.391e-04 | -8.88 | JIANG_TIP30_TARGETS_UP | MSigDB lists | JIANG_TIP30_TARGETS_UP | 42 | 13 | 17758 | 1761 |
WEE1,ENPP1,PPP1R2,CYR61,AXL,ITGA6,PTTG1,NDC80,BCL6,RAD17,NDE1,CDK1,IER3 |
| 1.391e-04 | -8.88 | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | 42 | 13 | 17758 | 1761 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,NRG2,ERBB2,NRG1,ERBB3,PHLPP1,GAB1 |
| 1.391e-04 | -8.88 | BURTON_ADIPOGENESIS_PEAK_AT_24HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_24HR | 42 | 13 | 17758 | 1761 |
HMMR,TOP2A,KIF20A,CDC20,PTTG1,BUB1,NUSAP1,ISYNA1,CCNB1,ANLN,UBE2C,CDK1,MELK |
| 1.399e-04 | -8.87 | Interleukin receptor SHC signaling | REACTOME pathways | R-HSA-912526 | 238 | 44 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,INPP5D,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,JAK1,PPP2R5A,FGFR2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 1.407e-04 | -8.87 | purine nucleoside binding | molecular function | GO:0001883 | 1798 | 228 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADORA1,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RHOA,RAB3B,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 1.408e-04 | -8.87 | insulin receptor signaling pathway | biological process | GO:0008286 | 305 | 52 | 16441 | 1675 |
PRKAA2,SPRED1,SORBS1,PSME2,RASA2,CALM3,PSMD10,ERBB2,NRG2,PSME1,PDGFB,SPTB,FGF19,PDGFA,CALM2,ATP6V0B,PSMD1,IGF1R,SHC3,PIK3CA,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,AKT1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,STRADB,BCAR1,PSMA4,RASA1,RHEB,GPLD1,IRS2,PRKAG2,IDE,JAK1,FGFR2,CAB39,EIF4EBP2,NRG1,SPTBN5,GRIN2D,JAK3,GAB1,RRAGD |
| 1.414e-04 | -8.86 | FRIDMAN_SENESCENCE_UP | MSigDB lists | FRIDMAN_SENESCENCE_UP | 77 | 19 | 17758 | 1761 |
ING1,IGFBP6,CDKN1C,S100A11,TP53,HTATIP2,OPTN,RABGGTA,CCND1,CTGF,ALDH1A3,TFAP2A,IRF7,IGFBP2,NRG1,CITED2,CDKN2D,IGSF3,CYP1B1 |
| 1.415e-04 | -8.86 | negative regulation of organelle organization | biological process | GO:0010639 | 290 | 50 | 16441 | 1675 |
GAS2L1,PINK1,ADD1,CKAP2,EPS8,PTTG1,ARFGEF1,TP53,PSMD10,BCL2L1,CCNB1,HDAC6,APC2,SPTB,LMNA,IER3,RPS6KA2,BMP7,TBCD,NEK2,VAT1,BUB1,ESPN,TACSTD2,TWIST1,PLK1,SIRT1,PPIF,AKT1,CDC20,RGCC,PIF1,CCNF,SLC25A5,NUBP1,TRIM9,SWAP70,PLEKHH2,MID1IP1,FGFR2,TRIOBP,AURKA,TMOD2,SPTBN5,HMGA1,SHROOM2,TBC1D4,UBE2C,ESPL1,JARID2 |
| 1.429e-04 | -8.85 | HTLV-I infection | KEGG pathways | hsa05166 | 258 | 48 | 6908 | 758 |
IL15RA,IL15,HLA-E,HLA-F,PTTG1,TP53,TGFBR1,MRAS,BCL2L1,PDGFB,ETS1,PRKACA,APC2,HLA-A,FZD6,CCND1,CDKN2C,PDGFA,ZFP36,RANBP1,DLG1,BAX,PIK3CA,PIK3CD,HLA-C,TLN2,WNT3A,MYBL1,DVL2,MAP3K3,AKT1,FZD4,CDC20,PIK3R1,MYBL2,ELK1,CD40,SLC25A5,FOS,FZD7,HLA-B,JAK1,SLC25A4,ETS2,NFKBIA,FZD5,CCNB2,JAK3 |
| 1.429e-04 | -8.85 | HTLV-I infection | KEGG pathways | ko05166 | 258 | 48 | 6908 | 758 |
IL15RA,IL15,HLA-E,HLA-F,PTTG1,TP53,TGFBR1,MRAS,BCL2L1,PDGFB,ETS1,PRKACA,APC2,HLA-A,FZD6,CCND1,CDKN2C,PDGFA,ZFP36,RANBP1,DLG1,BAX,PIK3CA,PIK3CD,HLA-C,TLN2,WNT3A,MYBL1,DVL2,MAP3K3,AKT1,FZD4,CDC20,PIK3R1,MYBL2,ELK1,CD40,SLC25A5,FOS,FZD7,HLA-B,JAK1,SLC25A4,ETS2,NFKBIA,FZD5,CCNB2,JAK3 |
| 1.431e-04 | -8.85 | GNF2_CD53 | MSigDB lists | GNF2_CD53 | 59 | 16 | 17758 | 1761 |
HLA-E,INPP5D,RPS6KA1,HLA-F,TAP1,SELL,ARHGDIB,PSME1,GRK6,HLA-A,TAPBP,HLA-B,FXYD5,OSTF1,HLA-C,PIK3CD |
| 1.431e-04 | -8.85 | CORRE_MULTIPLE_MYELOMA_DN | MSigDB lists | CORRE_MULTIPLE_MYELOMA_DN | 59 | 16 | 17758 | 1761 |
EZR,TGFBR1,SLC1A3,BLVRA,FBXO6,BARD1,FBLN1,TNFRSF19,FOS,HOXA9,CDCA5,NEK2,ALDH7A1,CADPS2,HS3ST3B1,SULF2 |
| 1.436e-04 | -8.85 | CELLULAR_LOCALIZATION | MSigDB lists | CELLULAR_LOCALIZATION | 368 | 59 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,TP53,ARFGEF1,PDIA3,SYTL4,BCL2L1,BARD1,ERP29,ZFYVE9,APPBP2,PDIA4,M6PR,ATG4A,KIF5B,ZFYVE16,DOPEY2,AP1M2,CARD8,CDH1,KIF13B,REEP1,STEAP2,ABCA2,BCL6,TINAGL1,ARL4D,LMAN1,F2R,TRAM1,KDELR1,MDFI,ATG4D,SUN2,ZWINT,AKT1,COG2,HTATIP2,STRADB,KIF1C,NUSAP1,NPC2,ICMT,NIN,OPTN,KLHL2,KCNMB4,SCG2,CDCA5,NOD2,CTSA,LTBP2,CENPE,ARSB,SHROOM2,NRBP1,ABCA1,ABCG1 |
| 1.450e-04 | -8.84 | cellular response to hormone stimulus | biological process | GO:0032870 | 687 | 100 | 16441 | 1675 |
GAS2L1,SPRED1,SORBS1,SLC2A4,UGT8,THRA,PSME2,NRG2,ERBB2,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,FOSB,PIK3CA,DAB2IP,GOT1,RASGEF1A,NR2C1,RASGRP1,FRS3,THRB,AKT1,CASP9,PRKAR2B,POR,RHEB,SOCS3,IRS2,ENPP1,ATP1A1,IDE,JAK1,CAB39,SLC27A1,EIF4EBP2,ADIPOR1,SPTBN5,NRG1,NR3C2,GAB1,NR2C2,RRAGD,PRKAA2,NKX3-1,RASA2,CALM3,PSMD10,FGF19,HDAC9,TFAP4,IGF1R,BMP7,IGFBP2,KLF9,ERBB3,NCAM1,MYO5A,NCOA2,PAQR7,RASGRF1,PSMB4,NR3C1,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,YES1,ELK1,FOS,BBS2,BCAR1,PSMA4,RASA1,GPLD1,FECH,GNAS,CTSL,NCOA3,PRKAG2,PLOD2,FGFR2,NR1D2,NR4A3,GRIN2D,NR4A2,GPER1,PLOD3,JAK3,TBC1D4,CPEB2,RARG |
| 1.450e-04 | -8.84 | Oocyte meiosis | KEGG pathways | ko04114 | 112 | 26 | 6908 | 758 |
CCNE2,PLK1,REC8,CPEB4,RPS6KA1,CDC20,PTTG1,CALM1,CALM3,ITPR2,PKMYT1,ITPR3,CCNB1,PRKACA,CDK1,CALM2,RPS6KA2,IGF1R,PPP2R5A,ITPR1,AURKA,BUB1,CCNB2,CPEB2,ESPL1,MAPK12 |
| 1.450e-04 | -8.84 | Oocyte meiosis | KEGG pathways | hsa04114 | 112 | 26 | 6908 | 758 |
CCNE2,PLK1,REC8,CPEB4,RPS6KA1,CDC20,PTTG1,CALM1,CALM3,ITPR2,PKMYT1,ITPR3,CCNB1,PRKACA,CDK1,CALM2,RPS6KA2,IGF1R,PPP2R5A,ITPR1,AURKA,BUB1,CCNB2,CPEB2,ESPL1,MAPK12 |
| 1.451e-04 | -8.84 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | 71 | 18 | 17758 | 1761 |
PLA2G4A,CD99,NFE2L3,HES1,LGALS3,ITCH,FXYD3,H2AFV,NFIB,CD83,ELF3,CTSC,A4GALT,IRF7,MDFIC,IFIT1,AHR,S100A13 |
| 1.451e-04 | -8.84 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 71 | 18 | 17758 | 1761 |
TGIF1,ARHGEF3,CD55,PRSS23,CDKN1C,SDC4,ARL4C,PKP2,IFIT3,TNFRSF19,SP4,EPCAM,CTGF,PPP2R5A,ABCB1,TACSTD2,SLC27A1,IFIH1 |
| 1.459e-04 | -8.83 | TENEDINI_MEGAKARYOCYTE_MARKERS | MSigDB lists | TENEDINI_MEGAKARYOCYTE_MARKERS | 65 | 17 | 17758 | 1761 |
CCNE2,CASP3,PDGFC,CASP9,CCNB1,FOS,PDGFB,CDK1,RASA1,MECOM,RASGRP2,PDGFA,GATA2,CD9,CDKN1B,PIK3C2B,JARID2 |
| 1.467e-04 | -8.83 | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | MSigDB lists | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | 329 | 54 | 17758 | 1761 |
UNKL,SLC2A4,FRMD4A,GRHL2,EPAS1,RPS6KA1,MIER3,PBX3,PLXNA1,RAB6A,SDC1,FAM46C,NEO1,CCND1,TFAP4,MARCH8,WEE1,E2F7,UBE2Q2,GNB5,ITGB8,LYPD6,LHX6,UBE2J1,BCL6,IRF2,NTN4,TIPARP,CYP26B1,DPYSL5,TBC1D8B,FOXJ2,OXR1,ANO6,FNDC3A,TP53INP2,NFIB,MFAP3L,HLF,KLF12,CDK19,RBL1,PHLPP2,RAB11FIP1,NR4A3,FAM117A,CLIP4,AGFG2,YOD1,NR4A2,ABCA1,RRAGD,RGMA,NR2C2 |
| 1.476e-04 | -8.82 | V$HFH8_01 | MSigDB lists | V$HFH8_01 | 193 | 36 | 17758 | 1761 |
LASP1,FRMD4A,CPEB4,HOXB7,ETV5,ARFGEF1,KCTD12,HMGN3,BEX2,CCND1,TFAP4,FOXP2,ARTN,SLC16A6,FLRT3,LMO4,KLF3,CYP26B1,TGIF1,SSH3,NR4A1,SLC39A8,CBX6,RGAG1,YES1,NFIB,NIN,KLF12,PDLIM3,COL13A1,PELI2,NR4A2,PRIMA1,REEP4,TOB1,ABCA1 |
| 1.476e-04 | -8.82 | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | 193 | 36 | 17758 | 1761 |
LMO7,SPRED1,SSH1,FAM199X,DNAJB2,NDRG2,B4GALT4,NUCB2,DHRS3,PDGFB,HLA-A,SLC25A36,GNS,SNX18,SLC44A1,SGK1,PIM1,LGMN,DLG3,LRP11,TIAM1,MPP1,DNAJB14,ARF4,GPLD1,MMP15,AGPAT2,UAP1,NFKBIA,INPP4B,EFNA5,PER3,ICOSLG,CBX7,TOB1,JARID2 |
| 1.506e-04 | -8.80 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2279 | 275 | 17775 | 1757 |
HECA,GAA,LGR4,HSPG2,TSC22D3,RET,PSME1,CAMK1D,PLXNA1,SLC20A1,DAPK2,WEE1,MUC4,CTGF,ZFP36,FOSB,AOX1,STEAP2,PIK3CA,MARCH2,PACSIN1,TIPARP,KIFC2,ACVR1C,PBK,SLC35C1,TNS1,SAV1,SPNS3,COL12A1,PLK2,ATP7B,LIMK1,FAM114A1,BMP1,DHTKD1,WBSCR27,CDK17,FRMD4A,KIF23,MERTK,BMP2K,FRY,PIK3AP1,NEK2,DAPK1,PRKG1,ADCK2,MAP3K9,ALPK1,CACNA1D,GPR161,EPB41L5,ADCK3,PIP4K2C,MYBL2,STK17A,MMP15,CACHD1,SCARB2,PLEKHH2,TJP3,SLC4A4,AURKA,CDK18,DRP2,PER3,PLIN3,MAP3K5,NRBP1,ADAMTS16,DOCK9,SPRED1,SLC2A4,ST14,NLRX1,GALNT12,IQGAP1,RPS6KA1,PKP2,TESK2,GRK6,PRKACA,DDR1,MUC16,DAB2IP,EPHB4,MYO5B,COL6A2,RIPK2,COG2,SEPT6,SYNE2,KIF1C,SLC11A2,PRKCQ,PKMYT1,ITPR3,ZNF469,PRDM11,EPHA10,PPP2R5A,POPDC3,JAK1,SHROOM3,CDK19,AXL,PNPLA6,SLC27A1,MLKL,RGS14,SLC25A30,NR3C2,COBL,MAPK12,DENND5B,PKN1,DNAH3,SIX4,SNTA1,TMEM87B,FUT2,SLC27A6,PTEN,SGK3,ADAM15,SLC44A2,MAPK11,ERBB3,TPCN1,RASGRF1,B3GNT2,PIK3R1,CXorf57,FURIN,YES1,KIF11,GPLD1,ACVRL1,FGFR2,PGM2L1,ESPL1,MELK,OCLN,TLL2,LTBP1,CPT2,CAMKK1,EPHA4,FHDC1,MGAT5B,BTG3,RPS6KA2,ANKFN1,SLC44A1,DLG1,TLN2,PLK1,THRB,ATL1,CD55,ING1,CELSR2,CR2,ARFRP1,ROR1,IDH1,SESN1,STK17B,ADRBK2,TRIM9,KCNMB4,ZNF114,HPSE,WIPI1,MAP2,P4HA2,MADD,SP6,CAPN1,PRKAA2,CD99,ZNF395,PEX6,ADCK5,DAZAP1,IGF1R,GATA2,FRAS1,PIM1,MPHOSPH9,CCDC88A,SNX7,TESK1,STRADB,TCF7,EIF2AK1,PDK3,PDIK1L,RANBP9,C3orf58,PRX,MAPKAPK2,GNAS,ITGA7,PHLPP2,CDCA5,NLRC5,ALPK3,LTBP2,SHROOM2,JAK3,TOB1,LZTFL1,NF2,IL15,TP53,ERBB2,COL18A1,TDRKH,FAM198B,LPIN3,PLK4,CDH3,F2R,SCYL3,CTH,FRS3,MAP3K3,AKT1,MAP3K6,STK38,PTK7,ANXA9,REEP4,BIN1,GOLIM4,PINK1,ENO2,CDH22,MACC1,HAL,PSMD10,COL4A5,TGFBR1,NOTUM,TRIB2,SBF1,AIP,NRP2,HMGXB4,IRF2BPL,ADRBK1,CDK16,TFAP2A,SGK1,BUB1,ABCD1,SYK,IGDCC4,NFE2L3,NR3C1,OGDHL,COL7A1,ARHGAP24,FAT4,SERPINA1,C2orf70,TMC5,NETO2,UACA,L1CAM,HIPK3,RAB3IL1,DIS3L |
| 1.516e-04 | -8.79 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | 186 | 35 | 17758 | 1761 |
PLA2G4A,IL15RA,PSME2,HLA-E,HLA-F,TAP1,SELL,PDIA3,BTN3A1,PSME1,LGALS3BP,RCN1,TYMP,AIM1,APOBEC3G,ERAP2,FAM69A,GCLC,LPGAT1,SNTB2,PLEKHO1,CDA,PSMA4,CASP4,FAS,SECTM1,PRPS2,NMI,NOD2,ERAP1,IRF7,IFIH1,APOL2,ISOC1,TMEM131 |
| 1.516e-04 | -8.79 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | 186 | 35 | 17758 | 1761 |
DDX58,PARP12,IL15,TAP1,HERC5,SAMD9,CD274,HERC6,DTX3L,SP100,TRANK1,FAM46A,GRHL1,ZNRF2,IFIT1,OAS3,APOBEC3G,DDX59,PARP9,MX1,TGIF1,PLSCR1,USP18,IFIT3,ZNF618,SEMA4D,TRIM69,C19orf66,SECTM1,NLRC5,NR4A3,IRF7,CMPK2,IFIH1,IFI6 |
| 1.520e-04 | -8.79 | GNF2_CKS1B | MSigDB lists | GNF2_CKS1B | 37 | 12 | 17758 | 1761 |
KIF20A,ASPM,CDC20,RANBP1,NDC80,CDCA8,BUB1,CENPE,UBE2C,KIF11,ESPL1,MELK |
| 1.520e-04 | -8.79 | CELL_SUBSTRATE_ADHESION | MSigDB lists | CELL_SUBSTRATE_ADHESION | 37 | 12 | 17758 | 1761 |
SGCE,SORBS1,FBLN5,ITGA3,NF2,PTEN,ACVRL1,COL13A1,ITGA7,TESK2,ADAM15,RASA1 |
| 1.524e-04 | -8.79 | MORI_IMMATURE_B_LYMPHOCYTE_DN | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_DN | 90 | 21 | 17758 | 1761 |
HMMR,CENPA,TXN,DLGAP5,CDC20,NUSAP1,CCNB1,H2AFV,CDK1,PRDX4,PRIM1,CDKN2C,TOP2A,DCK,CDCA5,NEK2,IQGAP3,CCNB2,UBE2C,E2F8,MELK |
| 1.552e-04 | -8.77 | GSE12366_GC_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_DN | 179 | 34 | 17758 | 1761 |
SLC25A24,CD63,CAST,HEXB,SELL,BTN3A1,IL13RA1,CAMK1D,HERC6,HLA-A,DTX3L,SNX18,OPN3,FXYD5,SLC39A10,PLCB2,PARP9,HES1,CD55,ARAP2,IFITM3,PLEKHO1,GYLTL1B,BTN3A2,ROR1,FNDC3A,CD83,C19orf66,ABCB1,FAM117A,NR4A2,PLOD3,SLC25A30,CBX7 |
| 1.552e-04 | -8.77 | vesicle-mediated transport | biological process | GO:0016192 | 1179 | 158 | 16441 | 1675 |
LAMP1,EXPH5,ILDR1,ARFGEF1,TGOLN2,ITPR2,SYTL4,PDGFB,DNER,SH3KBP1,CALM2,SUSD2,RAB15,AP1M2,ELMO2,DPYSL2,STEAP2,PIK3CA,SNX16,RAB20,RP2,PIK3CD,TINAGL1,CTTN,MARCH2,SCARA3,PACSIN1,S100A13,RASGRP1,XKR8,LAMP2,EZR,ARFRP1,KIF13A,LOXL2,MCFD2,ADRBK2,ARF4,OPTN,TRIM9,ENPP1,PLCG1,DNM1L,WIPI1,LIMK1,RAB11FIP1,ARF6,GRN,ARAP3,MRC2,GGA1,BVES,CALM3,RAB6A,NCKAP1,MERTK,FAM21C,DOPEY2,SNX18,RINL,GATA2,RIMS3,EXOC8,SORL1,CADPS2,PIKFYVE,SYTL3,PPP6R1,C9orf72,RIMS2,SNX7,KDELR1,KIF20A,CALM1,SCRIB,EIF2AK1,STX3,MAPKAPK2,AP1AR,CSNK1G1,MFSD2A,ITPR1,SH3BP4,PLD1,ARPC2,PLIN3,HOOK1,NRBP1,SNX30,EHD1,TRIP10,RALBP1,FTH1,BCL2L1,EMP2,TMPRSS4,BCAP31,SYTL2,ZFYVE9,PDGFA,PLCG2,RAB27B,LMAN1,SNX10,CHP1,MYO5B,CLCN3,SEC23A,COG2,KIF1C,ITPR3,SNX12,TAPBP,AXL,CORO1C,SYT13,ABCA1,ARFGEF3,BIN1,ANXA3,PACSIN2,SORT1,CD63,ATP9A,HABP4,LRP4,ARL4C,CTSZ,LGALS3BP,VPS26A,M6PR,CXCL16,ADRBK1,ADORA1,CTSC,CDK16,LLGL2,CD9,SYK,MYO5A,RAB3B,PIK3R1,COL7A1,YES1,NEURL1B,BBS2,MAPK8IP1,SCRN2,SERPINA1,SYT7,RAB11FIP2,FGFR2,NR4A3,ARRB1,ITGAV,TBC1D4,ESYT2,SNPH |
| 1.552e-04 | -8.77 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | 27 | 10 | 17758 | 1761 |
MDK,CD99,MX1,KLK10,ALDH2,IFITM3,SOX9,IRF7,IFIT1,IFI6 |
| 1.552e-04 | -8.77 | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | MSigDB lists | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | 27 | 10 | 17758 | 1761 |
MX1,H1F0,HOXA9,ARL4C,BCL6,SELL,CR2,TCF7,FHL1,NOTCH3 |
| 1.563e-04 | -8.76 | RICKMAN_METASTASIS_UP | MSigDB lists | RICKMAN_METASTASIS_UP | 322 | 53 | 17758 | 1761 |
ACACB,MRPL44,ARMCX3,UPF3B,ALDH6A1,HJURP,HEBP1,ATP9A,LRP4,ETV5,TMX4,FAM134A,PSMD10,DHX8,DNAJB11,FGF19,BEX2,APPBP2,ABCD4,PDIA4,RASSF8,MDM1,PSMD1,PAIP2B,TSPAN6,FAM13B,PASK,TPST1,ARMCX6,ETV4,FARP2,SALL4,SLC11A2,FAM133B,RAD17,IDH1,TCEAL8,GNAS,AMZ2,MFAP3L,GPRC5B,NGFRAP1,PRCP,BHLHB9,TCEAL4,PGRMC1,ZNF704,DTX4,SFMBT1,SH3BGRL2,GEM,LNP1,ZBTB33 |
| 1.577e-04 | -8.75 | V$NFY_Q6_01 | MSigDB lists | V$NFY_Q6_01 | 253 | 44 | 17758 | 1761 |
SLC2A4,PPP4R4,GRHL2,UGP2,CIT,SLC25A13,ETV5,PDIA3,HMGN3,PRKACA,CDH1,ZCCHC12,SHC3,PASK,FOSB,TMEM143,NEK2,ANKRD12,GLB1L2,RFX5,KLF9,DLG3,SPRY2,DPYSL5,PLK1,SUN2,GCA,RHOA,KIF20A,PIK3R1,LDB2,BORA,TYSND1,PPP2R5A,DOLPP1,FAM117A,AGFG2,DHTKD1,HDAC1,NDE1,E2F8,JARID2,DOCK9,NR2C2 |
| 1.584e-04 | -8.75 | receptor binding | molecular function | GO:0005102 | 1429 | 186 | 16491 | 1673 |
CASP3,EPHA4,TAP1,NRG2,IL18,NENF,SYTL4,CCNB1,PDGFB,DNER,CMTM6,TRIM68,GRM5,CALM2,TYMP,MUC4,CTGF,ELMO2,NPNT,SHC3,IL6ST,CABP1,SIVA1,DLG1,MANF,SEMA3G,ACOX2,TIAM1,S100A13,SMAGP,ITCH,IDH1,ARF4,PGF,MDK,PLCG1,ENPP1,GPRC5B,WIPI1,MADD,BMP1,GLA,F2RL1,GRN,SEMA6B,SERPINE2,HLA-E,ITGA6,HLA-F,CALM3,TEC,FBLN1,MESDC2,MARCH8,ITGA3,IGF1R,CYR61,CD70,WNT3A,LRIF1,ULBP2,SYTL3,TRAK2,SOCS5,MICB,CALM1,GNA11,RASA1,CDK5R1,GNAS,NCOA3,ETS2,PVRL2,SEMA4D,PLPP3,CSF1,RAET1L,EGFL7,NR4A2,GDF11,SEMA3A,JAK3,TOB1,APOL2,COL16A1,RARG,GAS2L1,SPRED1,SORBS1,NF2,IL15,TP53,ERBB2,EMP2,BCAP31,TNFSF9,ARHGEF16,SYTL2,PDGFA,NOV,SP100,ARTN,DOK4,REEP1,DAB2IP,PDE4D,DLG3,F2R,MED30,DVL2,FRS3,SEMA3B,SIRT1,DOCK4,TIMP2,RIPK2,S100A4,UTRN,ERBB2IP,ALCAM,FZD7,GABARAPL1,CMTM7,IRS2,TAPBP,PTPRJ,IDE,JAK1,NGFRAP1,SECTM1,SIPA1L1,NRG1,EFNA5,ABCA1,LIFR,CMTM4,NUDT6,CTHRC1,NKX3-1,MACC1,ARHGEF11,LRP4,HMGN3,GDF15,TGFBR1,PKN1,AIP,SRPX2,EFNB1,FGF19,HLA-A,CXCL16,ADRBK1,ADORA1,ANKS1B,PTEN,BMP7,CD9,ADAM15,ECI2,CNPY3,SYK,NCOA2,OSGIN1,PVRL4,RASGRF1,PDGFC,FBLN5,PLSCR1,GUSB,PLAUR,RAPGEF2,PIK3R1,GRIN1,DIAPH2,YES1,HLA-B,SCG2,DBI,NETO2,ARRB1,ERAP1,HMGA1,ICOSLG,L1CAM,RGMA |
| 1.588e-04 | -8.75 | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | MSigDB lists | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | 32 | 11 | 17758 | 1761 |
FUCA1,APLP2,TIMP2,PRCP,S100A4,ITGA6,CST3,SPINT2,NUCB2,SEPP1,TIAM1 |
| 1.593e-04 | -8.74 | macromolecular complex binding | molecular function | GO:0044877 | 1394 | 182 | 16491 | 1673 |
CASP3,ADD1,HDAC6,PDGFB,SPTB,EPCAM,CTGF,UBE2T,GRHL1,STIM1,NPNT,DPYSL2,MITF,MYH14,TLN2,PLK1,THRB,SMARCA2,CENPA,KIFC2,ITCH,MTRF1L,EZR,KIF13A,LOXL2,ENPP1,MSL1,MAP2,PLK2,TRAF3IP1,HDAC1,HOXC13,PRKAA2,LASP1,RUNX2,MRC2,LGALS3,PEX6,ITGA6,DNAJB2,SOX9,PDCL,KIF23,NDUFA4,NCKAP1,FBLN1,PSIP1,ITGA3,IGF1R,CYR61,GATA2,KIF13B,SORL1,PIM1,CCDC88A,DPYSL5,KIF20A,CORO2A,PYM1,HMG20B,TCF7,ELK1,ANTXR1,GNA11,GNAS,PTPRF,AP1AR,NCOA3,H1F0,PLPP3,CDCA5,NFKBIA,FAM83D,CABIN1,NDE1,ARPC2,SHROOM2,IFIH1,COL16A1,APOL2,GAS2L1,MTM1,LZTFL1,SORBS1,NF2,GRHL2,THRA,IQGAP1,TP53,PKP2,PRKACA,EMP2,APC2,DDR1,BCAP31,PDGFA,CCND1,NOV,SP100,KIF14,DOK4,REEP1,BCL6,CDKN1B,DAB2IP,RPN2,ESPN,FRS3,CHP1,SIRT1,CAMSAP3,SEC61B,TIMP2,CAPN6,COG2,SYNE2,UTRN,KIF1C,NUSAP1,ATP1B1,RAB38,ERBB2IP,KCTD2,DAG1,GABARAPL1,IRS2,SHROOM3,CORO1C,TRIOBP,TLE1,SPTBN5,MLKL,RGS14,REEP4,CBX7,PCOLCE,CPEB4,ADGRG1,HMGN3,PKN1,HLA-A,HMGXB4,KIF5B,TOP2A,ADORA1,PTEN,TOX2,TFAP2A,BAX,KLC3,CD9,ADAM15,CITED2,CLIP2,SYK,CRTAP,NCOA2,SUN2,TGIF1,FBLN5,LCA5,FMN1,AMFR,PIK3R1,EIF5A2,SYBU,PPARA,AIF1L,FOS,KIF11,CTSL,PITX2,CDK5RAP1,ACVRL1,CTSV,ARRB1,HMGA1,CENPE,GPER1,CPEB2,L1CAM,JARID2 |
| 1.594e-04 | -8.74 | regulation of cellular component biogenesis | biological process | GO:0044087 | 697 | 101 | 16441 | 1675 |
NF2,SSH1,ADD1,THRA,ARFGEF1,TP53,PKP2,HDAC6,PRKACA,SDC1,MNS1,SPTB,EPS8L2,CTGF,LMO4,KIF14,MITF,DLG1,PLK4,CDKN1B,DAB2IP,ESPN,TWIST1,TACSTD2,CTTN,PLK1,SSH3,PTGER4,EZR,PRKCQ,LDB2,DAG1,DPYSL3,TRIM9,PTPRJ,IDE,DNM1L,BHLHB9,PLK2,CORO1C,LIMK1,TRAF3IP1,FAM110C,TRIOBP,KLF5,EFNA5,SPTBN5,TMOD2,PIEZO1,ARF6,RAP1GAP,F2RL1,COBL,FBLIM1,PINK1,BMF,HJURP,TBC1D1,DNAJB2,SOX9,EPS8,SDC4,TGFBR1,NCKAP1,SRPX2,ADGRB2,SIX4,CTNNBIP1,CYR61,PTEN,BMP7,FLRT3,TBCD,GTF2F2,BAX,ATP8B1,SORL1,PIKFYVE,CNOT6L,FARP2,EPB41L5,RHOA,FMN1,RAPGEF2,PIK3R1,GRIN1,PIP4K2C,RGCC,EPHA1,RASA1,FAS,ARHGAP24,NUDT16,SWAP70,ACVRL1,PLD1,ARPC2,FZD5,COL16A1,AHR,ADAMTS16 |
| 1.605e-04 | -8.74 | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | MSigDB lists | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | 165 | 32 | 17758 | 1761 |
PRKAA2,IER5L,SSH1,EPAS1,AASS,DNAJB11,BCL2L1,IL17RB,GNS,LRRC45,WEE1,UBE2T,LLGL2,DOK4,N4BP3,PLEKHF1,F2R,ZNF365,TGIF1,TIMP2,PTPN9,LPGAT1,GCLC,NUSAP1,ATP1B1,STX3,CORO1C,SETD3,UBE2C,REEP4,SNX30,ADAMTS16 |
| 1.605e-04 | -8.74 | ACTTTAT,MIR-142-5P | MSigDB lists | ACTTTAT,MIR-142-5P | 276 | 47 | 17758 | 1761 |
SUN1,CDK17,SORBS1,SCOC,CPEB4,EPAS1,TRIP10,BVES,VANGL1,FXYD3,FAM134A,SLC25A27,MIER3,PBX3,ARHGEF40,SIX4,BTG3,RNF128,ZFP36,BHLHE41,CNNM4,SNX16,WWP1,EGLN3,ATP2B1,CHSY3,CLCN3,RHOA,FOXJ2,MGAT4B,UBE2A,ATP1B1,FNDC3A,ALCAM,FOS,FZD7,TMEM54,SLC4A4,SYT7,NETO2,NRG1,KLF11,OSR1,CPEB2,ABCA1,AHR,RGMA |
| 1.617e-04 | -8.73 | actin cytoskeleton organization | biological process | GO:0030036 | 399 | 64 | 16441 | 1675 |
SORBS1,NF2,SSH1,ADD1,TMSB15A,TRIP10,TESK2,F11R,MRAS,FAM101B,EMP2,TMSB15B,PDGFA,FRYL,DLG1,BCL6,ESPN,CTTN,MYH14,EPB41L4B,PACSIN1,EZR,ARHGDIB,ABR,DPYSL3,PDLIM3,SHROOM3,PTK7,LIMK1,CORO1C,SIPA1L1,TRIOBP,PRKCDBP,TMOD2,SPTBN5,ARF6,ITPKA,COBL,FGD1,WASF3,PACSIN2,ARHGEF11,EPS8,NCKAP1,SIX4,FRY,LLGL2,PRKG1,LIMCH1,FARP2,EPB41L5,RHOA,FMN1,CORO2A,STRADB,DIAPH2,ANTXR1,BCAR1,SWAP70,RND3,ARRB1,FGD6,ARPC2,SHROOM2 |
| 1.618e-04 | -8.73 | MHC_I_a_a1/a2 | interpro domains | IPR001039 | 18 | 8 | 18293 | 1814 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 1.625e-04 | -8.73 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 144 | 29 | 17758 | 1761 |
EXPH5,DOCK4,CENPA,NR3C1,MICB,GNE,TMX4,KIF23,PHLPP1,CCNB1,FNDC3A,KIF11,APPBP2,SLC25A36,LRRC42,TOP2A,FGFR2,FRYL,KIF14,SLC9A6,MAP3K5,PIKFYVE,ZMIZ1,MAST4,CCNB2,ATP2B1,KLF7,JARID2,DOCK9 |
| 1.628e-04 | -8.72 | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | 151 | 30 | 17758 | 1761 |
CASP3,MTM1,TGIF1,MBP,FAM160A1,ST14,S100A4,USP18,ITCH,SDC4,TCF7,IL18,PHLPP1,FAM81A,IL18R1,SP4,SYTL2,NEO1,HDAC9,GABARAPL1,EPCAM,PTPRJ,JAK1,ITGB8,UAP1,MATN2,ABCA2,LGMN,CBX7,S100A6 |
| 1.631e-04 | -8.72 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 11219 | 1178 | 17775 | 1757 |
HECA,AK7,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,PRKAR2B,ABR,ENPP1,PLCG1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,FAM21C,RABGGTA,MARCH8,TFAP4,FRY,MEGF8,FLRT3,RANBP1,MAP3K9,CADPS2,ALPK1,PANX2,MYLIP,DGKG,NUP85,MCCC2,HPS3,ELK1,NPHP3,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,TMEM159,RUSC1,ADAMTS16,DOCK9,NQO1,CD82,GRK6,MGST2,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,TMEM200B,MX1,COL6A2,C6orf1,RIPK2,HTATIP2,XRCC6BP1,ZNF618,SNX12,PDLIM3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,MAPK12,CTHRC1,CKAP2,HABP4,BTN3A1,SLC25A43,BEX2,CTNNBIP1,DIRAS3,IGSF9,MGAT4A,CST3,FAM20B,KLC3,FAM102A,MED22,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,CXorf57,AK4,CNTNAP1,PLOD2,SYT7,PPM1H,ITGAV,OSR1,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,NTN4,SCARA3,PLK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,KLF12,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,RASA2,ADCK5,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,PIM1,WNT3A,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,USP43,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,SYT13,ZMAT1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,LBR,PARM1,H1FX,NRP2,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,COL7A1,RNPEP,BBS2,DGKE,SMTNL2,SCG2,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LGR4,HSPG2,SSH1,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,FGD1,MRC2,TBC1D1,S100A2,TSPAN7,MESDC2,DOPEY2,AIM1,DAPK1,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,KCNJ12,PRSS23,ADCK3,LPGAT1,ATP8B3,ANTXR1,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,THRA,DDIT4L,ATP2C2,FTH1,DDR1,CYP39A1,ZFYVE9,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,UTRN,KIF1C,PKMYT1,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,SLC27A3,COBL,CBX7,IGFBP6,HAPLN3,EPS8,HERC5,FBXO6,DNAH3,EFNB1,HLA-A,SCML1,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,FARP2,TGIF1,PDGFC,ALDH2,B3GNT2,LONRF3,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,MELK,DEF6,UGT8,VARS2,MPP5,TRIM68,ZFYVE16,RAB15,SIPA1L2,ARHGEF37,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,ZNF165,CAPN1,PCSK5,ARAP3,SERPINE2,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,LMO7,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,PTPRU,GLO1,CD40,FANCE,CASP4,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,ENO2,ARHGEF11,TGFBR1,COL4A5,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,RAP2C,SPINT2,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,KLK10,ADD1,MRPS15,AASS,CACNA2D2,FAM102B,NRG2,DHX8,MORF4L2,SYTL4,EPDR1,DAPK2,CALM2,WEE1,AP1M2,PQLC2,PSMD1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,LOXL2,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,ARF6,GAB1,ALDH6A1,SLC36A4,MERTK,LMNA,ELF3,RAVER2,FAM13B,NEK2,NCAM1,C9orf72,SALL4,STAT4,MYBL2,SPTLC2,DHX32,STK17A,PTPRF,NCOA3,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,EGLN1,XDH,MTM1,CCDC109B,PAPSS2,GRHL2,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,RNF220,SP100,DACT1,ACSL4,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TNRC6C,PDIA3,ANO9,PKN1,ARHGEF40,ETS1,GSTP1,TIPRL,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,PLEKHF1,ADAM15,MAPK11,TPCN1,S100A6,AMOTL2,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,DCBLD1,UNKL,TRIM2,FAM199X,CUL4B,EPHA4,FHDC1,NDC80,TP53I11,HDAC6,SDC1,CNTRL,SHC3,MKRN3,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MAP2,DOLPP1,RAB11FIP1,PIK3C2B,EPB41L4A,PRKAA2,UBASH3B,CNTNAP2,IL18R1,IGF1R,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,CORO2A,SPATA13,EIF2AK1,ANKRD29,G2E3,MAPKAPK2,EPN3,COQ10A,CSF1,MFSD2A,ITGA7,LTBP2,IFI6,RNF146,AVPI1,NF2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,LPIN3,CYP26A1,RAD23A,EFR3A,PLCG2,N4BP3,SCN2A,CTH,SIRT1,CPD,MBP,FIGNL1,CDC20,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,AIFM3,NDST3,ZNF701,CMTM4,MAN2B2,GOLIM4,CD63,MACC1,RUSC2,PSMD10,GABRG2,NKRF,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,KLF9,TLE6,IGDCC4,DLGAP1,HMMR,PSMB4,NR3C1,AMFR,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,CD83,BANK1,FAT4,SERPINA1,TWSG1,TMC5,NETO2,FAM117A,CLIP4,PPP2R3C,SPCS3,TBC1D4,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,PLXNA1,SLC20A1,NCS1,CTGF,ELMO2,ZFP36,IQCE,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,RCAN3,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,PBK,HSPA12A,CASP9,NBPF3,TNS1,MCFD2,SLC25A5,SPNS3,ARHGEF26,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,DHTKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,C6orf106,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,PIK3AP1,BDH1,RUNDC3B,OPN3,SORL1,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,FADS2,B3GNT7,DDB2,PMPCB,ZNF84,TBC1D8B,MICB,AMER1,ANO6,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,NLRX1,S100A11,TRIP10,RPS6KA1,CAST,IQGAP1,BROX,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,FAM46A,CDKN1B,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,NIN,PRDM11,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNPY3,SPRY2,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,AMMECR1,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CPT2,CAMKK1,FLYWCH2,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,TSPAN6,IMPAD1,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,POF1B,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,KCNN4,RFX5,NCEH1,LRIF1,GYLTL1B,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,PROM2,SLC25A24,PSME2,MORC4,TDRKH,ARHGEF16,SS18,SETDB2,FRYL,ZDHHC12,GOT1,RPN2,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,REEP4,LIFR,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,MLPH,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,MBNL3,LRRC66,OGDHL,DHRS2,HNRNPH2,OTUB2,L1CAM,SNPH |
| 1.634e-04 | -8.72 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043280 | 127 | 27 | 16441 | 1675 |
SIRT1,CASP3,NKX3-1,RHOA,ACVR1C,DAP,RET,CASP9,SLC11A2,BCAP31,FAS,TFAP4,CARD8,CTGF,CYR61,CTSC,NGFRAP1,BAX,DAPK1,CDKN1B,ARRB1,GPER1,MAP3K5,EGLN3,WNT3A,F2R,XDH |
| 1.643e-04 | -8.71 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | 194 | 36 | 17758 | 1761 |
LTBP1,SLC25A24,GRHL2,B4GALT4,FAM46C,CENPN,RCN1,ZNF823,GRHL1,BDH1,FUT8,PAPSS1,FAM20B,KLC3,ARVCF,MAPK11,ALDH7A1,MANF,CITED2,RCAN3,CTDSP2,RASGRP1,LONRF3,FAM133B,GTF2A2,ZBTB7B,CASP4,PRDX4,DNAJC10,KCNMB4,TIMP3,ETS2,RGS14,RAP1GAP,AHR,RRAGD |
| 1.643e-04 | -8.71 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | 194 | 36 | 17758 | 1761 |
DYNLRB1,ARHGEF3,HJURP,S100A11,ST14,ARMC7,KIF23,FAM102B,KCTD12,TP53I11,B4GALNT1,ADD3,PTEN,CDK16,RIMS3,PHTF1,FXYD5,TRIM21,IRF2,SCYL3,S100A6,OPLAH,DDB2,PLEKHA6,GGH,ARHGDIB,EPHA1,POPDC3,TRIOBP,OVOL1,CLMN,GRAMD1C,CCNB2,MYL12B,ADAMTS16,STARD3NL |
| 1.643e-04 | -8.71 | GSE22886_NAIVE_BCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_DN | 194 | 36 | 17758 | 1761 |
GAA,PINK1,EPAS1,CD63,MRPS15,HEBP1,DCAF7,EFHD2,MGST2,DSE,VASH1,SIRPA,GNS,PSMD1,SLC16A6,MITF,CITED2,TIAM1,CCDC88A,KDELR1,PPIF,DOCK4,LAMP2,GCLC,RAPGEF2,ATP1B1,BLVRA,ABR,GABARAPL1,RBM47,DNM1L,GLA,PLIN3,ZMIZ1,NRGN,ISOC1 |
| 1.643e-04 | -8.71 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | 194 | 36 | 17758 | 1761 |
LAMP1,FRMD6,CAMKK1,ITGA6,SELL,KCTD12,BCL2L1,PHLPP1,SYTL2,RCN1,ADORA1,ITGB8,PIK3AP1,SNX18,SLC16A6,NTN4,RAB20,CACNA1D,NCEH1,SULT2B1,MGAT5,NEB,ATP1B1,NPC2,SESN1,CD83,SWAP70,ETS2,AXL,NETO2,INPP4B,TLE1,KLF11,LEMD1,LTA4H,RRAGD |
| 1.648e-04 | -8.71 | SIAE (sialic acid acetylesterase) | protein interactions | 54414 | 50 | 15 | 16036 | 1726 |
CHSY3,MAN2B2,HLA-B,TMEM30A,ERAP1,COL18A1,GDF11,FBXO6,GALNT7,PTGFRN,ARSB,ARSK,NRP2,KIAA1161,TMEM131 |
| 1.650e-04 | -8.71 | luminal_NS_carcinoma | COSMIC cancer mutations | luminal_NS_carcinoma | 54 | 15 | 17775 | 1757 |
CYP1A1,NFKBIE,CDH1,AKT1,PTEN,AMFR,AIM1,PIK3R1,NFKBIA,PIK3CA,TP53,ATP8B1,GRIN2D,GAB1,SIX4 |
| 1.650e-04 | -8.71 | breast-carcinoma-luminal_NS_carcinoma | COSMIC cancer mutations | breast-carcinoma-luminal_NS_carcinoma | 54 | 15 | 17775 | 1757 |
CYP1A1,NFKBIE,CDH1,AKT1,PTEN,AMFR,AIM1,PIK3R1,NFKBIA,PIK3CA,TP53,ATP8B1,GRIN2D,GAB1,SIX4 |
| 1.659e-04 | -8.70 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | 499 | 75 | 17758 | 1761 |
MTM1,FOXM1,ATP8A1,SLC25A13,EPHA4,TMX4,PJA2,FAM46C,RNF220,CNTRL,IL6ST,LMO4,KLF3,SLC44A1,CTTN,TMEM64,SLC39A10,F2R,CTDSP2,SEC23A,TIMP2,CITED4,CAPN6,SLC39A8,CASP9,UTRN,PRKAR2B,ERBB2IP,ZFAND5,SLC25A5,ALCAM,SP4,DPYSL3,MSL1,SHROOM3,EFNA5,RMND5A,LASP1,ABCG2,EFHD2,PBX3,C6orf106,TGFBR1,ETS1,SGPL1,MECOM,IRF2BPL,ADD3,CA2,PTEN,CTSC,FLRT3,PPP4R1,BUB1,PIM1,CNOT6L,PPP6R1,ALDH3A2,CKAP4,ATP2B1,TRAK2,PHF20L1,FADS2,ERMAP,PIK3R1,HMG20B,KIF11,PCTP,PITX2,MAPKAPK2,SERPINA1,FGFR2,TWSG1,FZD5,HIPK3 |
| 1.668e-04 | -8.70 | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | 97 | 22 | 17758 | 1761 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,FGFR2,PIK3CA,CDKN1B,GAB1,FRS3 |
| 1.670e-04 | -8.70 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 284 | 51 | 16036 | 1726 |
IQGAP1,RPS6KA1,RET,TP53,HDAC6,GSTP1,ETS1,BARD1,IER3,TOP2A,CCND1,RPS6KA2,GATA2,MITF,DAPK1,BCL6,NEK2,ADAM15,PDE4D,EGLN3,PTPRE,SPRY2,NEB,METAP2,FRS3,HMMR,TGIF1,MBP,TNIP1,NR3C1,NR4A1,SYNE2,CASP9,PPARA,DUSP4,ELK1,FOS,MAPKAPK2,PTPRF,NCOA3,ATP1A1,GNPTAB,RYK,ARRB1,KLF11,CENPE,NDE1,LIFR,GAB1,TOB1,MAPK12 |
| 1.675e-04 | -8.69 | negative regulation of nucleocytoplasmic transport | biological process | GO:0046823 | 70 | 18 | 16441 | 1675 |
TXN,NFKBIE,THRA,LITAF,RAB23,PSMD10,APC2,BARD1,NOV,SP100,CABP1,BMP7,NFKBIA,DAB2IP,MDFIC,PKIA,CHP1,MDFI |
| 1.690e-04 | -8.69 | PROTEIN_KINASE_ST | prosite domains | PS00108 | 309 | 53 | 11866 | 1235 |
PRKAA2,CDK17,PINK1,NUAK1,CIT,CAMKK1,RPS6KA1,TGFBR1,CAMK1D,GRK6,PKN1,PRKACA,BMP2K,DAPK2,WEE1,RPS6KA2,ADRBK1,CDK16,PASK,SGK3,DAPK1,PRKG1,MAP3K9,NEK2,SGK1,BUB1,PIM1,MAST4,PLK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,EIF2AK1,PKMYT1,PDIK1L,MAP3K6,STK17B,ADRBK2,CDK1,STK17A,MAPKAPK2,ACVRL1,CDK19,CSNK1G1,STK38,PLK2,AURKA,CDK18,MAP3K5,HIPK3,MELK |
| 1.691e-04 | -8.69 | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | 187 | 35 | 17758 | 1761 |
RMND5A,ANXA3,SPC25,FOXM1,BLVRB,KIF23,CALM3,CENPN,CALM2,BCL6,SERINC2,PCGF5,IFITM3,MPP1,SAT1,CALM1,STRADB,TNS1,RANBP9,CDK1,RHEB,ARF4,KLHL2,FECH,HPSE,H1F0,PVRL2,CDCA5,ADIPOR1,YOD1,RAP1GAP,UBE2C,ESPL1,E2F8,MELK |
| 1.691e-04 | -8.69 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | 187 | 35 | 17758 | 1761 |
CD99,BIN1,SLC35D2,ENO2,DAP,CD82,BLVRB,FBXO2,NANS,WEE1,KCNN4,DPYSL2,LMO4,BHLHE41,PLCG2,PAPSS1,UBE2J1,FAM102A,CD70,FAIM,RASGRP1,S100A6,SMAGP,SEC61B,GCLC,S100A4,SYBU,ATP1A1,AGBL5,CAB39,CTSA,GRAMD1C,ZMIZ1,TMEM14A,EHD1 |
| 1.691e-04 | -8.69 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | 187 | 35 | 17758 | 1761 |
LZTFL1,FAM169A,HLA-E,TSC22D3,RASA2,PPFIBP2,BTN3A1,LTBP3,MARCH8,ACAP2,LLGL2,PAIP2B,LYPD3,KLF3,DLG1,FXYD5,KLF9,ECE1,MYLIP,TPCN1,SMAGP,CD55,FOXJ2,ERBB2IP,ROR1,FOXL1,BSDC1,RASGRP2,MSL1,ATP1A1,RYK,FAM117A,TMEM159,TBC1D4,SNPH |
| 1.691e-04 | -8.69 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | 187 | 35 | 17758 | 1761 |
LAMP1,RUNX2,CRYM,HERC5,TEX2,NUCB2,SLC20A1,PDIA4,DAPK2,RAB15,BTG3,RPS6KA2,DACT1,MGAT4A,RRBP1,UBE2J1,MDFIC,TSPAN13,MARCH2,EGLN3,SEPHS1,SEC61B,GGH,NPC2,LHFPL2,CDK5R1,ATP13A2,MAPKAPK2,SCARB2,ALDH5A1,DCK,PTK7,IRF7,FHL1,TBC1D4 |
| 1.693e-04 | -8.68 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | WikiPathways | WP2291 | 16 | 8 | 4455 | 516 |
EXPH5,MLPH,MADD,SYTL4,RAB27B,MYRIP,SYTL3,SYTL2 |
| 1.698e-04 | -8.68 | HADDAD_B_LYMPHOCYTE_PROGENITOR | MSigDB lists | HADDAD_B_LYMPHOCYTE_PROGENITOR | 269 | 46 | 17758 | 1761 |
HLA-F,ABCG2,PLXNA1,SNN,TRIB2,BARD1,DDR1,TOP2A,CDKN2C,ZFYVE16,MDM1,DACT1,RIMS3,FJX1,CD9,CDKN1B,IRF2,PIK3CD,CITED2,PTPRE,RASGRP1,SCN3A,TGIF1,ARAP2,ELK3,ING1,SNTB2,EZR,KIF13A,DNAJB14,DCP2,ANKRD10,IRS2,NEIL1,BANK1,ALDH5A1,DCK,P4HA2,STK38,WFS1,LRIG1,ITPR1,TLE1,VSIG10,COBL,TOB1 |
| 1.702e-04 | -8.68 | actin filament-based process | biological process | GO:0030029 | 439 | 69 | 16441 | 1675 |
SORBS1,NF2,SSH1,ADD1,TMSB15A,TRIP10,TESK2,F11R,MRAS,FAM101B,EMP2,TMSB15B,PDGFA,FRYL,DLG1,BCL6,ESPN,CTTN,MYH14,EPB41L4B,PACSIN1,NEB,SYNE2,EZR,ARHGDIB,ABR,DPYSL3,PDLIM3,SHROOM3,PTK7,LIMK1,CORO1C,SIPA1L1,TRIOBP,PRKCDBP,TMOD2,SPTBN5,ARF6,ITPKA,COBL,FGD1,WASF3,PACSIN2,ARHGEF11,FRMD6,EPS8,NCKAP1,SIX4,FRY,LLGL2,PRKG1,LIMCH1,MYO5A,FARP2,EPB41L5,SUN2,RHOA,FMN1,CORO2A,STRADB,DIAPH2,ANTXR1,BCAR1,SWAP70,RND3,FGD6,ARRB1,ARPC2,SHROOM2 |
| 1.705e-04 | -8.68 | MODULE_194 | MSigDB lists | MODULE_194 | 14 | 7 | 17758 | 1761 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3,AOX1 |
| 1.709e-04 | -8.67 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 117 | 25 | 17758 | 1761 |
LMO7,LAMP2,ENO2,PLSCR1,CAPN6,PDK3,GTF2A2,PHLDA1,CASP4,PTEN,FGFR2,NPNT,CSF1,PGRMC1,AOX1,TPST1,TWIST1,LTBP2,NCAM1,SLC12A2,CCNB2,F2R,MYL12B,XDH,CYP1B1 |
| 1.709e-04 | -8.67 | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | 117 | 25 | 17758 | 1761 |
SHMT1,ZWINT,DLGAP5,FOXM1,KIF23,NUSAP1,YES1,H2AFV,CDK1,LBR,PSIP1,MECOM,PRIM1,CDKN2C,KIF14,RANBP1,FUT8,NEK2,AURKA,CENPE,UBE2C,SEMA3A,NRGN,ESPL1,MDFI |
| 1.711e-04 | -8.67 | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 54 | 15 | 17758 | 1761 |
COL9A3,FRY,GCLC,KCNN4,DBI,SFMBT1,PBX3,ROR1,MAP3K5,VASH1,ALDH3A2,APOBEC3G,ABR,CCDC88A,IGSF3 |
| 1.719e-04 | -8.67 | purine ribonucleoside binding | molecular function | GO:0032550 | 1795 | 227 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RHOA,RAB3B,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 1.721e-04 | -8.67 | transport vesicle | cellular component | GO:0030133 | 193 | 36 | 17570 | 1756 |
SORT1,SLC2A4,HLA-E,HLA-F,CTSZ,TGOLN2,RAB6A,SYTL4,ERP29,HLA-A,SYTL2,CTSC,CDK16,STEAP2,HLA-C,LMAN1,RAB27B,MYRIP,SYTL3,CHP1,CLCN3,SEC23A,SNTB2,FURIN,COL7A1,MCFD2,CRISPLD2,DPYSL3,GNAS,HLA-B,AP1AR,SERPINA1,TMEM30A,SYT13,NRGN,ARFGEF3 |
| 1.734e-04 | -8.66 | GSE3982_BASOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_UP | 180 | 34 | 17758 | 1761 |
DDX58,EPAS1,CD63,TSC22D3,OSGIN2,C6orf106,DSE,SIRPA,ZFYVE16,ADD3,TRANK1,SHC3,BCL6,DRAM1,WWP1,PTPRE,CLIP2,SOCS5,MBP,ARAP2,PARP4,CR2,SPTLC2,ATP10D,CASP4,RHEB,PIAS3,GALNT3,PPP2R5A,JAK1,CDK19,SLC4A3,MYL12B,CD33 |
| 1.734e-04 | -8.66 | GOLGI_APPARATUS | MSigDB lists | GOLGI_APPARATUS | 224 | 40 | 17758 | 1761 |
GOLIM4,IL15,GGA1,TGOLN2,RAB6A,DSE,SLC9A7,DOPEY2,FUT2,STEAP2,FUT1,LMAN1,F2R,MPHOSPH9,SCYL3,CCDC88A,B3GALT6,CLCN3,KIF20A,COG2,ACO1,FURIN,KIF1C,PKMYT1,OPTN,GLCE,GNAS,TAPBP,DNM1L,ATP7B,SECTM1,FGD6,GLA,PLD1,PLIN3,F2RL1,ABCG1,PCSK5,FGD1,GOLGB1 |
| 1.761e-04 | -8.64 | PLXNB1 (plexin B1) | protein interactions | 5364 | 17 | 8 | 16036 | 1726 |
PLCG1,RHOA,AKT1,RND3,ARHGEF11,SEMA4D,PLCG2,PLXNA1 |
| 1.766e-04 | -8.64 | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | 124 | 26 | 17758 | 1761 |
CCNE2,CTHRC1,FAM92A1,GRHL2,RIPK2,STAU2,ESRP1,OSGIN2,GGH,INTS8,OSR2,LACTB2,COX6C,FZD6,NKAIN3,PEX2,MATN2,ZNF704,SNX16,MRPS28,TMEM64,GEM,TRAM1,NCOA2,RIMS2,PKIA |
| 1.786e-04 | -8.63 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | 66 | 17 | 17758 | 1761 |
EXPH5,C3orf52,CXorf57,KCTD12,DUSP4,TRIB2,PHLDA1,EDNRA,ADORA1,PLK2,ITPR1,REEP1,MAP3K9,PDE4D,NEB,COBL,PKIA |
| 1.786e-04 | -8.63 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 66 | 17 | 17758 | 1761 |
HMMR,NR4A1,SAT1,FOS,EPCAM,TIMP3,ATP1A1,CDH1,CTGF,CA2,ZFP36,PLK2,FOSB,ITPR1,BCL6,SGK1,TIAM1 |
| 1.807e-04 | -8.62 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 403 | 63 | 17758 | 1761 |
LAMP1,PPP4R4,RUNX2,ZNF395,LGR4,CPEB4,NUAK1,COL4A5,MPP5,LBR,SIRPA,HMGXB4,FANCI,CCND1,RCN1,CTNNBIP1,CA2,ADRBK1,ELF5,FAM13B,KLF3,FOSB,IRF2,SGK1,MDFIC,ANO4,PDIA6,SPRY2,MDFI,MAP3K3,CHSY3,PPIF,SEC23A,CLCN3,TGIF1,CAPN6,CXorf57,PTGER4,C2orf69,MCFD2,BORA,LHFPL2,IDH1,CDK5R1,GLCE,NIN,FAS,SLC4A4,GPRC5B,RAB11FIP2,CSNK1G1,AMMECR1,LRIG1,OTUB2,PCDH19,CAB39,PITPNA,KLF5,MAP3K5,ARF6,NRGN,CPEB2,PKIA |
| 1.813e-04 | -8.62 | HSPE1 (heat shock 10kDa protein 1) | protein interactions | 3336 | 115 | 26 | 16036 | 1726 |
PPIF,CASP3,LASP1,SHMT1,ALDH2,TXN,ENO2,UGP2,ALDH6A1,SAT1,EZR,GLO1,SPR,IDH1,PLS3,RCN1,DCK,DBI,AKR1B1,TLE1,PGM2L1,GOT1,TAGLN2,LRIF1,CTH,GPX4 |
| 1.815e-04 | -8.61 | LANDIS_BREAST_CANCER_PROGRESSION_UP | MSigDB lists | LANDIS_BREAST_CANCER_PROGRESSION_UP | 43 | 13 | 17758 | 1761 |
GALNT3,CMAS,SHROOM3,CD82,KCNN4,DAP,FXYD3,AIM1,LITAF,TFAP2C,CYB561,ACSL4,NUCB2 |
| 1.819e-04 | -8.61 | DANG_REGULATED_BY_MYC_DN | MSigDB lists | DANG_REGULATED_BY_MYC_DN | 247 | 43 | 17758 | 1761 |
LAMP1,CASP3,GAA,CAST,GABRG2,ERBB2,FTH1,PDGFB,TSPAN7,PLS3,IER3,CCND1,CTGF,CALD1,KIF14,CDKN1B,ARVCF,IFIT1,PIM1,NCAM1,F2R,GM2A,CPD,LAMP2,DDB2,FADS2,FBLN5,TIMP2,AKT1,PLAUR,NPC2,MYL12A,ARF4,FAS,GNAS,NUCB1,WFS1,PRKCDBP,IRF7,PLD1,HSPB1,SERPINB1,KLF7 |
| 1.820e-04 | -8.61 | env (gp160; envelope glycoprotein) | protein interactions | 155971 | 1401 | 192 | 16036 | 1726 |
SUN1,LAMP1,CASP3,GAA,UGT8,TXN,IL15RA,HSPG2,CPT2,DNAJC3,DNAJB11,F11R,MGAT5B,OAT,CCNB1,HDAC6,DNER,SDC1,PDGFB,BARD1,PLS3,CALM2,AP1M2,SIVA1,DLG1,PIK3CA,TUBG1,CLDN4,PIK3CD,TIPARP,APOBEC3G,LAMP3,CD55,CASP9,EZR,CR2,PTGFRN,SLC25A5,CDK1,ARF4,ABR,PIAS3,MAN2A2,PLCH1,PLCG1,KCNMB4,MAP2,LIMK1,P4HA2,MADD,RAB11FIP1,PIK3C2B,ARF6,TRAF5,CAPN1,PCSK5,MRC2,RUNX2,HLA-E,HLA-F,CALM3,RAB6A,NCKAP1,B4GALT4,IL18R1,TSPAN7,ELF3,MESDC2,B3GALNT1,ITGA3,IGF1R,KCNN4,TPST1,HLA-C,GAD1,PLCB2,CKAP4,ABCC1,STAT4,CALM1,MGAT4B,FAM133B,GLT8D2,GNA11,FAS,STK17A,MAPKAPK2,TIMM8A,SEMA4D,CSF1,NFKBIA,PLD1,MAP3K5,ARPC2,PLIN3,JAK3,IFI6,PLA2G4A,UPF3B,NQO1,REPS2,IL15,ST14,IQGAP1,INPP5D,CD82,PDIA5,TP53,FTH1,CD274,BCL2L1,PRKACA,BCAP31,IER3,SP100,CDH1,PLCG2,BCL6,CDKN1B,OAS3,LGMN,LMAN1,PDIA6,ERLEC1,AKT1,PRKCQ,CD40,SOCS3,ARHGAP35,ATP1A1,JAK1,DDOST,FAM195A,ST3GAL1,MAPK12,MAN2B2,CD63,SDC4,SELL,PDIA3,COL4A5,NKRF,FBXO6,SEPP1,LGALS3BP,NRP2,VPS26A,HLA-A,PDIA4,TOP2A,CXCL16,PTEN,ALPP,ALG13,BMP7,MGAT4A,FUT8,CD9,BAX,GTF2F2,TFAP2A,MAPK11,TAGLN2,RASGRF1,ADAMTS2,RHOA,PLSCR1,IFITM3,PLAUR,PIK3R1,GRIN1,FURIN,TTC7A,RUNX3,FOS,PRDX4,CD83,FUCA1,ENDOD1,CTSL,HLA-B,SERPINA1,HNRNPH2,CTSV,PGRMC1,ABCB1,GRIN2D,SPCS3,ITGAV,PTGES,OCLN,GOLGB1 |
| 1.826e-04 | -8.61 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | 159 | 31 | 17758 | 1761 |
WASF3,FADS2,DLGAP5,CIT,SEPT6,LRP4,PTTG1,CDC20,PBX3,KIF23,CRABP2,KIF11,CDK1,FANCI,FZD7,PRIM1,TOP2A,APOBEC3B,SS18,COL13A1,HOXA9,KIF14,ABCA2,PLK4,AURKA,CCNB2,MPHOSPH9,ESPL1,NR2C1,MELK,CKS2 |
| 1.826e-04 | -8.61 | SHEPARD_BMYB_MORPHOLINO_DN | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_DN | 195 | 36 | 17758 | 1761 |
SLC25A24,DLGAP5,FOXM1,CKAP2,DAP,BLVRB,PDCL,KIF23,COL4A5,CCNB1,EPDR1,IRF2BPL,ACAP2,KIF14,IGFBP2,IQGAP3,LAMP2,PHF20L1,ASPM,SEPT6,DRAP1,MGAT4B,CDC20,CDCA2,ANLN,KIF11,CDK1,PRIM1,MDK,ATP1A1,DCK,CDCA7L,HMGA1,NDE1,MELK,GOLGB1 |
| 1.826e-04 | -8.61 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 195 | 36 | 17758 | 1761 |
S100A11,CD63,CAST,BLVRB,GNS,DPYSL2,DAPK1,RAB20,MTMR11,TIAM1,NAGA,S100A6,RHOA,MCTP1,MPP1,PLAUR,CDA,BLVRA,ZFAND5,CRISPLD2,ALDH3B1,HPSE,RBM47,ZDHHC7,CTSA,PPP2R3C,ZMIZ1,PLIN3,ARPC2,SLC27A3,LTA4H,NDFIP1,AHR,CPPED1,CD33,PCSK5 |
| 1.832e-04 | -8.60 | regulation of transport | biological process | GO:0051049 | 1736 | 221 | 16441 | 1675 |
LAMP1,EXPH5,ILDR1,TXN,LGR4,ATP8A1,CACNA2D2,IL18,ITPR2,SYTL4,CAMK1D,CACNB4,PDGFB,SDC1,BARD1,SLC8B1,ERP29,NCS1,CALM2,NKAIN3,ZFYVE16,RAB15,STIM1,CABP1,SIVA1,DPYSL2,PASK,KCNS3,DLG1,ABCA2,TRPC1,CRY2,RAB20,TMEM37,PACSIN1,MYRIP,RASGRP1,KCNIP3,ACVR1C,NBPF3,EZR,PRKAR2B,SLC25A5,ABR,TRIM9,ENPP1,PLCG1,KCNMB4,SLC25A4,DNM1L,RAB11FIP1,NOD2,CAB39,SARAF,ARF6,RAP1GAP,F2RL1,DDX58,PRSS8,SCN5A,BMF,SERPINE2,LGALS3,NFKBIE,BVES,FXYD3,HLA-E,UBASH3B,RAB23,SLC25A27,CALM3,FBLN1,MERTK,IL18R1,ANO1,CA2,GATA2,RIMS3,KCNN4,DAPK1,FXYD5,SORL1,MDFIC,CACNA1D,WNT3A,SYTL3,NUP85,RIMS2,MDFI,KCNJ12,CALM1,ANO6,CDK5R1,GNAS,PRKAG2,TMEM30A,NFKBIA,ITPR1,STK39,YOD1,ATP1B3,PLD1,JAK3,NUP58,TMEM173,EHD1,PROM2,SORBS1,THRA,IQGAP1,TP53,ERBB2,PKP2,CD274,PRKACA,APC2,BCAP31,SYTL2,IER3,NOV,CDH1,SP100,DACT1,PLCG2,REEP1,CDH3,DAB2IP,TWIST1,PDE4D,ACSL4,SCN2A,RAB27B,TSPAN1,F2R,MYT1,SCN3A,CHP1,SIRT1,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,UTRN,PRKCQ,ATP1B1,ITPR3,CD40,SNX12,FZD7,IRS2,ATP1A1,AXL,WFS1,INPP4B,EFNA5,NRG1,SYT13,ABCA1,BIN1,TCAF1,PINK1,PACSIN2,NKX3-1,CD63,SDC4,PSMD10,TGFBR1,HMGN3,ANO9,FGF19,WWP2,NEO1,KIF5B,SNTA1,CARD8,ADORA1,ADRBK1,GNB5,LLGL2,PTEN,CDK16,BMP7,FAM20B,SGK3,BAX,UBE2J1,SGK1,TMBIM6,MAPK11,TSPAN13,ERBB3,SYK,TPCN1,MYO5A,HES1,RASGRF1,RAB3B,RHOA,PIK3R1,SYBU,GRIN1,LITAF,PPARA,RGCC,GPLD1,NUCB1,BANK1,SYT7,NETO2,NR4A3,ARRB1,ITGAV,GPER1,SPCS3,FHL1,FZD5,NDFIP1,TBC1D4,PKIA,ABCG1 |
| 1.839e-04 | -8.60 | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | MSigDB lists | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | 152 | 30 | 17758 | 1761 |
DDX58,ARHGEF3,MBP,CITED4,ZNF395,CPT2,RPS6KA1,GALNT12,TSC22D3,PPFIBP2,ARFRP1,GRTP1,AIFM2,RNF19B,TSPAN7,MAPK8IP1,NCOA3,TMEM54,SP100,RIMS3,BDH1,CST3,SPINT2,PLEKHF1,LTBP2,SYT13,GLCCI1,SGCB,CBX7,TOB1 |
| 1.848e-04 | -8.60 | negative regulation of cell cycle | biological process | GO:0045786 | 464 | 72 | 16441 | 1675 |
GAS2L1,HECA,CASP3,CAST,PSME2,CTDSPL,PTTG1,TP53,PSME1,BCL2L1,VASH1,PRKACA,BARD1,FANCI,IER3,SUSD2,CCND1,CDKN2C,BTG3,PSMD1,RPS6KA2,DACT1,DLG1,CDKN1B,DAB2IP,CDKN2D,CTDSP2,PLK1,TIMP2,CDC20,RAD17,CCNF,SESN1,CDK1,RHEB,JADE1,PLK2,CAB39,HDAC1,OVOL1,E2F8,MAPK12,RRAGD,PRKAA2,NKX3-1,CDKN1C,PSMD10,TGFBR1,ETS1,TOP2A,TFAP4,E2F7,PTEN,BMP7,BUB1,ZWINT,PSMB4,NR4A1,RGCC,STRADB,SCRIB,RUNX3,NUBP1,PSMA4,CDK5RAP1,PRKAG2,FGFR2,CGREF1,FHL1,GPER1,UBE2C,ESPL1 |
| 1.862e-04 | -8.59 | kinase inhibitor activity | molecular function | GO:0019210 | 59 | 16 | 16491 | 1673 |
CASP3,SPRED1,CDKN1C,DNAJC3,PRKAR2B,TRIB2,MAPK8IP1,SOCS3,CDKN2C,PRKAG2,CDKN1B,HSPB1,CDKN2D,SPRY2,PKIA,CHP1 |
| 1.862e-04 | -8.59 | kinase activator activity | molecular function | GO:0019209 | 59 | 16 | 16491 | 1673 |
NKX3-1,IQGAP1,CALM1,RGCC,CALM3,CDK5R1,CALM2,PRKAG2,GPRC5B,MADD,PIK3CA,CAB39,NRG1,EFNA5,ERBB3,SPRY2 |
| 1.878e-04 | -8.58 | VEGFR2 mediated cell proliferation | REACTOME pathways | R-HSA-5218921 | 241 | 44 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,ITPR2,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,ITPR3,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 1.883e-04 | -8.58 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | 188 | 35 | 17758 | 1761 |
PRSS8,UGP2,IL15RA,ENO2,C5orf30,SELL,S100A2,IER3,BTG3,TYMP,AKR1B1,MTMR11,SMYD5,GM2A,FAM69A,LAMP3,MX1,PLK1,ZNF84,SLC39A8,ACO1,AK4,PRKAR2B,SLC11A2,ELK1,RNF19B,ETS2,FGFR2,H1F0,NFKBIA,NMI,IRF7,TRAF5,AHR,IFI6 |
| 1.883e-04 | -8.58 | GSE13306_TREG_VS_TCONV_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_UP | 188 | 35 | 17758 | 1761 |
CDKN1C,FRMD6,CAMKK1,RUSC2,RGS20,GABRG2,C3orf18,PHLDA1,FAM167A,FAM46A,ARSG,ZDHHC23,TMEM51,TNFRSF12A,DLG3,S100A13,ZNF462,PLEKHA6,CELSR2,CRB3,PPP1R14C,ICMT,ATP10D,ARF4,NFIX,ALDH5A1,RAB11FIP2,CSF1,NFKBIA,LRIG1,SECTM1,PRDM5,CDK18,PER3,ACOT7 |
| 1.883e-04 | -8.58 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | 188 | 35 | 17758 | 1761 |
BIN1,SIGIRR,ACACB,HECA,ZNF395,TSC22D3,TMX4,ARL4C,NUCB2,FAM46C,MARCH8,ADD3,GNB5,ZFP36,MGAT4A,FUT8,SORL1,SEMA3G,PDE4D,SUN2,SH3BGRL,PCBP3,S100A4,GRIN1,CR2,NUSAP1,PRKCQ,FOS,RASGRP2,MMP15,IRS2,PLCG1,NGFRAP1,NR3C2,TOB1 |
| 1.883e-04 | -8.58 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 188 | 35 | 17758 | 1761 |
BIN1,SCN5A,HLA-E,ITGA6,HABP4,ASAH1,NENF,B4GALT4,C3orf18,DENND2D,IL6ST,COL6A1,FAM63A,SORL1,WWP1,CRY2,PIK3CD,PIM1,PLCB2,ALDH3A2,CD55,TNIP1,FOXJ2,MGAT4B,LITAF,STX3,FUCA1,SCARB2,RPL12,DTX4,INPP4B,TBC1D4,NR3C2,APOL2,EHD1 |
| 1.883e-04 | -8.58 | GSE3982_MAC_VS_TH1_UP | MSigDB lists | GSE3982_MAC_VS_TH1_UP | 188 | 35 | 17758 | 1761 |
SLC25A24,REPS2,TMX4,RGS20,ERI2,NDRG2,FTH1,PLXNA1,DPP8,BMP2K,MARCH8,APLP2,DOPEY2,EFR3A,DACT1,DRAM1,VAT1,TACSTD2,KLF9,ACOX2,TLN2,SPRY2,SOCS5,GCA,MMD,SAT1,RC3H2,CXorf57,SESN1,RHEB,ARHGAP24,SWAP70,ZDHHC7,ITGAV,ANXA9 |
| 1.890e-04 | -8.57 | KEGG_OOCYTE_MEIOSIS | MSigDB lists | KEGG_OOCYTE_MEIOSIS | 111 | 24 | 17758 | 1761 |
CCNE2,PLK1,REC8,RPS6KA1,CALM1,PTTG1,CDC20,CALM3,ITPR2,PKMYT1,ITPR3,CCNB1,PRKACA,CDK1,CALM2,RPS6KA2,PPP2R5A,IGF1R,ITPR1,AURKA,BUB1,CCNB2,ESPL1,MAPK12 |
| 1.890e-04 | -8.57 | VANTVEER_BREAST_CANCER_METASTASIS_DN | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_DN | 111 | 24 | 17758 | 1761 |
CCNE2,CENPA,SPC25,DEPDC1,DLGAP5,HJURP,ASPM,NDC80,NUSAP1,GGH,GPSM2,CENPN,FAM64A,CDK16,DCK,MGAT4A,KIF14,AURKA,BUB1,CCNB2,NIPA1,MELK,RRAGD,CKS2 |
| 1.898e-04 | -8.57 | Neurotrophin signaling pathway | KEGG pathways | hsa04722 | 120 | 27 | 6908 | 758 |
MAP3K3,RHOA,SORT1,AKT1,RIPK2,NFKBIE,RPS6KA1,PIK3R1,CALM1,TP53,CALM3,ARHGDIB,MAPKAPK2,CALM2,PLCG1,RPS6KA2,SHC3,NGFRAP1,PLCG2,NFKBIA,PIK3CA,BAX,MAPK11,PIK3CD,MAP3K5,GAB1,MAPK12 |
| 1.898e-04 | -8.57 | Neurotrophin signaling pathway | KEGG pathways | ko04722 | 120 | 27 | 6908 | 758 |
MAP3K3,RHOA,SORT1,AKT1,RIPK2,NFKBIE,RPS6KA1,PIK3R1,CALM1,TP53,CALM3,ARHGDIB,MAPKAPK2,CALM2,PLCG1,RPS6KA2,SHC3,NGFRAP1,PLCG2,NFKBIA,PIK3CA,BAX,MAPK11,PIK3CD,MAP3K5,GAB1,MAPK12 |
| 1.900e-04 | -8.57 | ribonucleoside binding | molecular function | GO:0032549 | 1798 | 227 | 16491 | 1673 |
ACACB,NMRK1,AK7,ATP8A1,CAMKK1,EPHA4,RET,TAP1,DHX8,VARS2,CAMK1D,ABCD4,DAPK2,WEE1,RAB15,RPS6KA2,UBE2T,PAPSS1,PASK,PIK3CA,ABCA2,TUBG1,RAB20,RP2,MYH14,PIK3CD,DDX59,PLK1,NLRP4,ATL1,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,ARFRP1,KIF13A,PIF1,ROR1,CDK1,STK17B,ADRBK2,ARF4,RHEB,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,NOD2,PIK3C2B,ITPKA,ARF6,RRAGD,DDX58,PRKAA2,RUNX2,CDK17,LMTK3,PEX6,NUAK1,DGKQ,ABCG2,RAB23,KIF23,RAB6A,TEC,MERTK,BMP2K,C9orf69,UBE2Q2,IGF1R,KIF13B,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIM1,PIKFYVE,MAST4,DGKG,MCCC2,ABCC1,KIF20A,TESK1,ADCK3,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,ATP8B3,NUBP1,PDIK1L,GNA11,STK17A,DHX32,DGKH,GNAS,MAPKAPK2,NUDT16,PRKAG2,CSNK1G1,DCK,PRPS2,NLRC5,RHOBTB2,AURKA,ALPK3,STK39,CDK18,MAP3K5,IFIH1,JAK3,NRBP1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TP53,ERBB2,TESK2,MRAS,GRK6,PRKACA,DDR1,TRANK1,KIF14,SRR,PLK4,EPHB4,OAS3,ACSL4,RAB27B,ARL4D,SCYL3,SEPHS1,MYO5B,MX1,MAP3K3,CLCN3,RIPK2,AKT1,FIGNL1,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,RAB38,PKMYT1,ATP10D,MAP3K6,NIN,ARHGAP35,ATP13A2,EPHA10,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,STK38,PTK7,MLKL,ABCA1,MAPK12,PINK1,TOR4A,ATP9A,CIT,GNE,ARL4C,TGFBR1,PKN1,DNAH3,KIF5B,DIRAS3,TOP2A,ADRBK1,CDK16,FAM20B,GTF2F2,SGK3,UBE2J1,SGK1,ATP8B1,BUB1,MAPK11,ABCD1,ERBB3,SYK,ATP2B1,MYO5A,OPLAH,RHOA,RAB3B,GCLC,UBE2A,NADK2,AK4,RUNX3,YES1,KIF11,DGKE,SWAP70,RND3,FGFR2,ACVRL1,RAP2C,ABCB1,RYK,LRRK1,CENPE,GEM,CMPK2,UBE2C,HIPK3,MELK,ABCG1 |
| 1.903e-04 | -8.57 | EF-hand_7 | pfam domains | PF13499 | 89 | 21 | 16629 | 1696 |
SLC25A24,KCNIP3,CALM1,CALB2,CALM3,EFHD2,NUCB2,MCFD2,MYL12A,HPCAL4,PPP2R3A,NCS1,PLS3,CALM2,DUOX1,NUCB1,PLCH1,CABP1,CGREF1,DGKG,CHP1 |
| 1.921e-04 | -8.56 | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | MSigDB lists | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | 85 | 20 | 17758 | 1761 |
CCNE2,PPIF,ZWINT,DLGAP5,CDC20,NDC80,NUSAP1,GGH,KIF11,CDK1,LEPR,SAC3D1,APOBEC3B,TOP2A,AMMECR1,BUB1,MINPP1,CCNB2,NUP85,MELK |
| 1.936e-04 | -8.55 | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | 181 | 34 | 17758 | 1761 |
DDX58,PARP12,DLGAP5,SPC25,TAP1,KIF23,HERC5,SAMD9,HERC6,TMC1,LGALS3BP,DTX3L,CYP4F11,IFIT1,OAS3,LAMP3,PARP9,REC8,MX1,HMMR,PLSCR1,IFITM3,PBK,USP18,BLVRA,SNTB1,IFIT3,TRIM69,AXL,NMI,IRF7,CMPK2,IFIH1,IFI6 |
| 1.941e-04 | -8.55 | cell differentiation involved in embryonic placenta development | biological process | GO:0060706 | 27 | 10 | 16441 | 1675 |
E2F7,GRHL2,AKT1,ST14,SPINT2,PLK4,FZD5,E2F8,MDFI,SOCS3 |
| 1.945e-04 | -8.55 | regulation of nervous system development | biological process | GO:0051960 | 709 | 102 | 16441 | 1675 |
EMX1,FOXO6,NF2,SSH1,EPHA4,RET,TP53,PLXNA1,CAMK1D,PRKACA,GRM5,NCS1,IL6ST,KIF14,DPYSL2,BCL6,DLG1,DUSP10,DAB2IP,DIXDC1,SEMA3G,NOTCH3,CTTN,PACSIN1,TIAM1,DVL2,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,CDK1,RHEB,ARHGAP35,DPYSL3,GPRC5B,BHLHB9,PLK2,PTK7,LIMK1,TRAF3IP1,SIPA1L1,EFNA5,NRG1,ITPKA,ARF6,RGS14,LZTS1,COBL,GRN,BIN1,WASF3,SEMA6B,SERPINE2,ADGRG1,CIT,SOX9,LRP4,ETV5,CRABP2,SRPX2,ADGRB2,SIX4,ITGA3,PTEN,GATA2,MEGF8,BMP7,MYCL,FLRT3,KIF13B,KIAA0319,SORL1,TNFRSF12A,WNT3A,CCDC88A,GPR161,TLE6,RIMS2,HES1,TGIF1,RHOA,MMD,ASPM,RAPGEF2,GRIN1,HMG20B,NPHP3,CDK5R1,CDK5RAP1,PTPRF,SEMA4D,TMEM30A,CSF1,GPER1,GDF11,SOX8,ARSB,SEMA3A,L1CAM,RARG |
| 1.953e-04 | -8.54 | BROWNE_HCMV_INFECTION_20HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_DN | 98 | 22 | 17758 | 1761 |
HMMR,LTBP1,TRIM2,NQO1,ALDH6A1,ACO1,DIAPH2,SRPX2,ADD3,ST5,ITGA3,FRY,CTGF,WIPI1,NR1D2,RND3,AXL,SIPA1L1,MAP3K5,F2R,AHR,ATP2B1 |
| 1.953e-04 | -8.54 | GAGCCTG,MIR-484 | MSigDB lists | GAGCCTG,MIR-484 | 98 | 22 | 17758 | 1761 |
HSPG2,PTGER4,NFE2L1,SNN,DAG1,TYSND1,COL12A1,M6PR,MAPKAPK2,PTPRF,PLEKHH2,KLF12,DPYSL2,DOLPP1,TRIOBP,PCDH19,PITPNA,SP6,NFKBIZ,CEP41,SCARA3,PTPRE |
| 1.956e-04 | -8.54 | negative regulation of protein depolymerization | biological process | GO:1901880 | 59 | 16 | 16441 | 1675 |
GAS2L1,ADD1,CKAP2,EPS8,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2 |
| 1.971e-04 | -8.53 | MHC_I | pfam domains | PF00129 | 18 | 8 | 16629 | 1696 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 1.982e-04 | -8.53 | protein localization | biological process | GO:0008104 | 1685 | 215 | 16441 | 1675 |
SUN1,LAMP1,EXPH5,LTBP1,UGT8,HSPG2,ARFGEF1,TAP1,F11R,MPP5,SYTL4,HDAC6,NUP62CL,ERP29,ZFYVE16,RAB15,AP1M2,NPNT,DLG1,SNX16,SUN3,RAB20,RP2,CTTN,TLN2,PACSIN1,TRAM1,MYRIP,S100A13,PLK1,LAMP2,KCNIP3,CENPA,EZR,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,CDK1,ARF4,OPTN,DNM1L,WIPI1,UEVLD,GNPTAB,RAB11FIP1,NOD2,ARF6,F2RL1,RRAGD,NXT2,PCSK5,NFKBIE,GGA1,PEX6,SOX9,ETV5,RAB23,RAB6A,NCKAP1,CNTNAP2,FAM21C,LMNA,ATG4A,MESDC2,DOPEY2,SNX18,RINL,FRAS1,RPL39,KIF13B,EXOC8,SORL1,CADPS2,PIKFYVE,WNT3A,SYTL3,NUP85,RIMS2,MDFI,SNX7,KDELR1,TRAK2,PMPCB,KIF20A,BTN3A2,STRADB,SCRIB,NUBP1,STX3,GNAS,AP1AR,SCARB2,TIMM8A,TMEM30A,NFKBIA,SH3BP4,FAM83D,ZDHHC7,AURKA,CTSA,LTBP2,ATP1B3,SHROOM2,HOOK1,JAK3,TOB1,NUP58,SNX30,EHD1,MTM1,ARMCX3,THRA,C5orf30,TP53,PKP2,MVB12B,EMP2,STIL,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,ATP6V0B,SVBP,ACAP2,CDH1,KIF14,ZDHHC12,REEP1,BCL6,ZDHHC23,RPN2,IFIT1,LMAN1,RAB27B,DLG3,ARL4D,SNX10,F2R,DVL2,CHP1,ATG4D,MYO5B,SEC23A,SEC61B,AKT1,COG2,PTPRU,SYNE2,SLC11A2,ATP1B1,ERBB2IP,RAB38,PYGO1,SNX12,ATP10D,DAG1,DDOST,SHROOM3,CORO1C,PEX2,ABCA1,TTC8,PINK1,PACSIN2,CD63,TSPAN15,FRMD6,LRP4,BTN3A1,PDIA3,PSMD10,AIP,VPS26A,SIX4,SLC9A2,ZDHHC21,PDIA4,KIF5B,ADORA1,MLPH,RNF128,BMP7,RRBP1,BAX,PLEKHF1,SYK,MYO5A,SUN2,HES1,RAB3B,FBLN5,LCA5,CRB3,RAPGEF2,PIK3R1,EIF5A2,PRICKLE1,NEURL1B,BBS2,CNTNAP1,RPL12,MAMDC4,RAB11FIP2,SCG2,ARRB1,SPCS3,CEP41,PLOD3,WDR45B,RAB3IL1,ABCG1 |
| 1.991e-04 | -8.52 | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | 23 | 9 | 17775 | 1757 |
GNAS,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 1.991e-04 | -8.52 | biliary_tract-gallbladder-other-adenoma | COSMIC cancer mutations | biliary_tract-gallbladder-other-adenoma | 23 | 9 | 17775 | 1757 |
GNAS,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 2.008e-04 | -8.51 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 233 | 41 | 17758 | 1761 |
CCNI,LTBP1,LASP1,CDKN1C,GNPDA1,ATP8A1,ITGA6,SOX9,SDC4,MMADHC,PDIA5,AES,KCTD12,SLC20A1,SDC1,PHLDA1,TFAP4,ADD3,CYR61,KCNN4,PLK4,ATP8B1,CTH,PPIF,DDB2,TIMP2,PLAUR,RAPGEF2,MYBL2,AK4,RUNX3,EPHA1,NPC2,ATP1B1,ASB13,MYL12A,MMP17,ITGA7,RAP1GAP,AFAP1,EHD1 |
| 2.019e-04 | -8.51 | SMIRNOV_RESPONSE_TO_IR_2HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 49 | 14 | 17758 | 1761 |
PLK2,SOX9,RAB11FIP1,PTGER4,SGK1,KLF5,GDF15,PIM1,RNF19B,SESN1,TNFSF9,FAS,CD83,IER3 |
| 2.019e-04 | -8.51 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | 49 | 14 | 17758 | 1761 |
MARCH8,SMARCA2,ZNF395,FRY,AASS,KIF13B,CASP9,CRY2,DIXDC1,FOS,SESN1,ARHGEF40,LTBP3,CYBRD1 |
| 2.019e-04 | -8.51 | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | MSigDB lists | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | 49 | 14 | 17758 | 1761 |
HLA-B,TAPBP,PSME2,TAP1,PDIA5,PDIA3,ERAP1,PSME1,HLA-C,PDIA6,PSMA4,HLA-A,ERAP2,KDELR1 |
| 2.022e-04 | -8.51 | KORKOLA_TERATOMA | MSigDB lists | KORKOLA_TERATOMA | 38 | 12 | 17758 | 1761 |
CENPA,ZWINT,DLGAP5,ZFP36,CDC20,EPS8,MRS2,AURKA,NUF2,NFKBIZ,CCNB1,CKS2 |
| 2.028e-04 | -8.50 | GSE360_DC_VS_MAC_L_DONOVANI_DN | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_DN | 196 | 36 | 17758 | 1761 |
ENO2,TSC22D3,RPS6KA1,CTDSPL,SEPP1,DHRS3,BCAP31,PDIA4,RPS6KA2,CD9,TMBIM6,MDFIC,IFIT1,MANF,CTDSP2,ALDH3A2,PPIF,PGM1,ZWINT,CD55,ZC3H11A,GUSB,GCLC,MPP1,SH3BGRL,MRS2,RASA1,FRMD4B,ALDH5A1,RND3,STK38,TRAF3IP1,DTX4,PPM1H,GEM,USF2 |
| 2.028e-04 | -8.50 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_UP | 196 | 36 | 17758 | 1761 |
HLA-E,SDC4,HMGN3,BCL2L1,GPSM2,SH3KBP1,APOBEC3B,TFAP2A,PLEKHF1,IRF2,MDFIC,IQGAP3,SNX10,SMAGP,PHF20L1,NR3C1,USP18,MPP1,SAT1,NUB1,GRIN1,FNDC3A,RNPEP,SPTLC2,HLA-B,ACADSB,PVRL2,CSF1,HDAC1,IRF7,STK39,ITGAV,CENPE,ITPKA,RGS14,JARID2 |
| 2.028e-04 | -8.50 | PLASARI_TGFB1_TARGETS_10HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_UP | 196 | 36 | 17758 | 1761 |
NUDT6,PAPSS2,NUAK1,TGFBR1,LPIN3,SLC20A1,PDGFB,CARD10,TMCC3,IER3,PDGFA,CTGF,FJX1,ALDH1A3,CNNM4,TNFRSF12A,ALS2CL,CTH,PDGFC,PLAUR,SPATA13,DUSP4,CD40,RNF19B,CRISPLD2,ZNF469,ENDOD1,GALNT3,ENPP1,TIMP3,KCNK1,MFSD2A,ABCB1,UNC5B,F2RL1,MAFF |
| 2.028e-04 | -8.50 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN | 196 | 36 | 17758 | 1761 |
PINK1,ADD1,HLA-E,ZCCHC24,ETV5,BTN3A1,KCTD12,MGST2,ITPR2,PKN1,VASH1,ERP29,FRY,METTL7A,IQCE,ATP5H,PLCG2,RUNDC3B,SORL1,AHCY,CLIP2,ALDH3A2,CORO2A,S100A4,FOS,IDH1,POR,FUCA1,PRCP,STK38,PNPLA6,NRG1,HOXB13,NRGN,LTA4H,ABCG1 |
| 2.033e-04 | -8.50 | pallium development | biological process | GO:0021543 | 149 | 30 | 16441 | 1675 |
ANXA3,EMX1,CASP3,RHOA,NF2,ADGRG1,TACC1,ASPM,GRIN1,TFAP2C,CNTNAP2,BBS2,CDK5R1,MDK,FOXP2,FAT4,PTEN,PHLPP2,KIF14,LHX6,NR4A3,BAX,DIXDC1,DAB2IP,ZBTB18,WNT3A,WDR62,NDE1,SEMA3A,BTBD3 |
| 2.041e-04 | -8.50 | BIOCARTA_RAS_PATHWAY | MSigDB lists | BIOCARTA_RAS_PATHWAY | 23 | 9 | 17758 | 1761 |
RHOA,AKT1,RALBP1,CASP9,PIK3R1,PIK3CA,PLD1,BCL2L1,ELK1 |
| 2.041e-04 | -8.50 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | MSigDB lists | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | 23 | 9 | 17758 | 1761 |
DGKH,DGKQ,PRKCQ,ITPR2,ITPR3,DGKG,RASGRP1,DGKE,RASGRP2 |
| 2.046e-04 | -8.49 | response to lipid | biological process | GO:0033993 | 785 | 111 | 16441 | 1675 |
CASP3,NQO1,IL15,THRA,RET,ERBB2,IL18,CCNB1,PDGFB,SDC1,CALM2,CCND1,CYP1A1,SP100,CTGF,PLCG2,FOSB,SRR,ABCA2,CLDN4,DUSP10,CDKN1B,DAB2IP,GOT1,PDE4D,CDKN2D,F2R,NR2C1,THRB,RIPK2,AKT1,CITED4,PTPRU,FZD4,CASP9,PTGER4,ERBB2IP,CD40,IDH1,FZD7,ABR,SOCS3,MDK,ATP1A1,CDK19,MAP2,PTK7,AXL,NOD2,NR3C2,ABCA1,NR2C2,PRKAA2,GRN,ANXA3,NKX3-1,SOX9,CALM3,SELL,TGFBR1,ETS1,GSTP1,TFAP4,CXCL16,CA2,PTEN,GATA2,BMP7,CST3,TFAP2A,BAX,IGFBP2,KLF9,PIM1,CITED2,WNT3A,PAQR7,RHOA,NR3C1,NR4A1,MICB,CALM1,LITAF,PPARA,YES1,PDK3,ELK1,FOS,FAS,GPLD1,FECH,GNAS,MMP15,MAPKAPK2,PITX2,NCOA3,TIMP3,NR1D2,CTSV,NFKBIA,NR4A3,AURKA,NR4A2,GPER1,HOXB13,CMPK2,OSR1,ARSB,PTGES,RARG,ABCG1 |
| 2.056e-04 | -8.49 | regulation of protein kinase B signaling | biological process | GO:0051896 | 122 | 26 | 16441 | 1675 |
SIRT1,TXN,PINK1,ARFGEF1,TGFBR1,PHLPP1,SESN1,DAG1,KIAA1161,PDGFA,SESN3,BANK1,PTPRJ,IGF1R,HPSE,PTEN,AXL,INPP4B,DLG1,FAM110C,PRKCDBP,NRG1,MYDGF,GPER1,SPRY2,XDH |
| 2.056e-04 | -8.49 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 644 | 92 | 17758 | 1761 |
LAMP1,PLA2G4A,DLGAP5,FOXM1,AASS,GALNT12,CTDSPL,NDC80,NANS,CCNB1,STIL,BCAP31,FANCI,LMO4,AKR1B1,GOT1,TECR,PDIA6,DVL2,CYP1B1,PLK1,ENPP4,CENPA,C3orf52,CDC20,HTATIP2,NUSAP1,PRKAR2B,GLO1,CD40,CDK1,DAG1,OPTN,SLC25A4,RBL1,NGFRAP1,DNM1L,HOXA9,PEX2,INPP4B,DHTKD1,SERPINB6,CMAS,ENO2,SERPINE2,LRRFIP2,PDIA3,C6orf106,CTSZ,GPSM2,LMNA,FZD6,MECOM,M6PR,TOP2A,FAM111A,GATA2,BAX,NEK2,ECI2,PIM1,CKAP4,HMMR,FADS2,ZWINT,KIF20A,PRSS23,ASPM,CXorf57,BLVRA,PDK3,KIF11,NFIB,PRDX4,SWAP70,TIMP3,ETS2,PLOD2,HNRNPH2,KBTBD2,SPINT2,SLC2A6,RYK,AURKA,CENPE,FZD5,TMEM14A,CCNB2,TBC1D4,ESPL1,PKIA,MELK |
| 2.080e-04 | -8.48 | ZHANG_BREAST_CANCER_PROGENITORS_DN | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_DN | 139 | 28 | 17758 | 1761 |
CPD,PPP1R2,ZC3H11A,CAST,HDAC11,KIF23,IL18,FNDC3A,BCAP31,DAG1,SOCS3,CXCL16,CACHD1,TAPBP,SCNN1A,CSF1,RANBP1,SRR,VAT1,ARRDC1,MDFIC,TACSTD2,NFKBIZ,MTMR11,ANXA9,PIK3CD,PLOD3,GLCCI1 |
| 2.080e-04 | -8.48 | LEE_NEURAL_CREST_STEM_CELL_UP | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_UP | 139 | 28 | 17758 | 1761 |
GRN,SORBS1,ELK3,S100A11,ZCCHC24,C3orf52,LITAF,ROR1,CRABP2,PHLDA1,ALCAM,HOXB2,CYP26A1,NRP2,EDNRA,PITX2,CDH1,DACT1,MITF,RRBP1,TFAP2A,HMGA1,ERBB3,L1CAM,TRIM62,LZTS1,SCN3A,MDFI |
| 2.085e-04 | -8.48 | negative regulation of developmental process | biological process | GO:0051093 | 777 | 110 | 16441 | 1675 |
GAS2L1,GRHL2,FOXM1,TSC22D3,INPP5D,EPHA4,TP53,PKP2,ERBB2,IL18,VASH1,PRKACA,FAM101B,CCND1,NOV,ELF5,BCL6,DUSP10,CDH3,VAT1,CDKN1B,DAB2IP,TWIST1,TACSTD2,DIXDC1,SEMA3G,NOTCH3,LGMN,ETV4,SEMA3B,SIRT1,ACVR1C,ARHGDIB,SAV1,FZD7,ABR,DPYSL3,ENPP1,PLK2,CORO1C,HOXA9,TRAF3IP1,NKD1,INPP4B,HDAC1,NRG1,ARF6,ABCA1,SEMA6B,PINK1,SORT1,NKX3-1,ADGRG1,CIT,UBASH3B,SOX9,LRP4,TGFBR1,TRIB2,FBLN1,ADGRB2,SIX4,PTEN,GATA2,BMP7,BHLHE41,VASN,CST3,KIAA0319,SORL1,MAPK11,WNT3A,TRIM62,GPR161,SOCS5,HES1,RHOA,MFI2,ASPM,RAPGEF2,PIK3R1,PPARA,MBNL3,RGCC,PRICKLE1,NPHP3,BBS2,NFIB,CDK5R1,GNAS,NCOA3,AP1AR,TWSG1,SEMA4D,ACVRL1,TBX18,NFKBIA,SFMBT1,ITGAV,GPER1,GDF11,SOX8,OSR1,NDFIP1,JAK3,SEMA3A,TOB1,RARG,ABCG1,XDH |
| 2.094e-04 | -8.47 | C2 | pfam domains | PF00168 | 122 | 26 | 16629 | 1696 |
PLA2G4A,MCTP1,CAPN6,ITCH,RASA2,SYTL4,RASA1,SYTL2,ABR,PLCG1,CPNE2,PLCH1,RAB11FIP2,SYT7,RGS3,RIMS3,PLCG2,RAB11FIP1,DAB2IP,WWP1,PIK3C2B,SYT13,PLCB2,SYTL3,RIMS2,ESYT2 |
| 2.095e-04 | -8.47 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 189 | 35 | 17758 | 1761 |
CASP3,LZTFL1,EPAS1,CKAP2,C5orf30,DHRS3,C11orf95,CMTM6,BMP2K,PDIA4,PDGFA,TAF1B,RIMS3,PPP4R1,OPN3,DAPK1,SGK1,BTBD3,SPRY2,SCN3A,MCTP1,PLSCR1,MMD,USP18,LRRC1,DCP2,PLCH1,KCNMB4,CORO1C,ABCB1,NR4A3,PGRMC1,SPCS3,NDFIP1,PKIA |
| 2.119e-04 | -8.46 | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | MSigDB lists | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | 73 | 18 | 17758 | 1761 |
MX1,ARAP2,PARP12,IFITM3,SLC39A8,NUB1,HERC5,CD274,IFIT3,CD40,CDK1,IRF7,OAS3,IFIT1,IFIH1,APOBEC3G,IFI6,LAMP3 |
| 2.139e-04 | -8.45 | LY_AGING_OLD_DN | MSigDB lists | LY_AGING_OLD_DN | 55 | 15 | 17758 | 1761 |
PLK1,CENPA,FOXM1,CTSC,KIF14,CDC20,RANBP1,MYBL2,KIF23,PKMYT1,CCNF,CCNB1,UBE2C,KIF11,BARD1 |
| 2.140e-04 | -8.45 | AGC-kinase_C | interpro domains | IPR000961 | 55 | 15 | 18293 | 1814 |
RPS6KA2,ADRBK1,AKT1,CIT,RPS6KA1,STK38,SGK3,PRKG1,SGK1,PRKCQ,GRK6,PKN1,MAST4,PRKACA,ADRBK2 |
| 2.167e-04 | -8.44 | CAIRO_HEPATOBLASTOMA_CLASSES_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_CLASSES_DN | 204 | 37 | 17758 | 1761 |
PSME2,ZCCHC24,TSC22D3,COL18A1,CAMK1D,PHLDA1,HDAC9,SGPL1,CYP1A1,FRY,TRANK1,IL6ST,AOX1,ABCA2,BCL6,TFAP2A,DAPK1,MTMR11,SGCB,MYRIP,MAST4,ALDH3A2,AMOTL2,RASGRF1,ALDH2,LDB2,CASP4,FAS,GABARAPL1,MFAP3L,SLC4A4,FAT4,KCNK1,NR1D2,NFKBIA,MAP3K5,MYL12B |
| 2.170e-04 | -8.44 | BURTON_ADIPOGENESIS_1 | MSigDB lists | BURTON_ADIPOGENESIS_1 | 33 | 11 | 17758 | 1761 |
IRS2,WEE1,CTGF,ETS2,ARL4C,LITAF,SGK1,NR4A2,PHLDA1,MAFF,IER3 |
| 2.173e-04 | -8.43 | response to peptide hormone | biological process | GO:0043434 | 555 | 83 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,PSME2,NRG2,ERBB2,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,SESN3,PSMD1,CTGF,SHC3,PIK3CA,CDKN1B,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,AKT1,ACVR1C,PRKCQ,PRKAR2B,POR,DAG1,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,GAB1,RRAGD,PRKAA2,SORT1,RASA2,CALM3,PSMD10,FGF19,HDAC9,IGF1R,BMP7,ERBB3,NCAM1,MYO5A,GCNT1,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,NR4A3,NR4A2,GRIN2D,GPER1,JAK3,TBC1D4,CPEB2 |
| 2.184e-04 | -8.43 | JAEGER_METASTASIS_DN | MSigDB lists | JAEGER_METASTASIS_DN | 249 | 43 | 17758 | 1761 |
EXPH5,PRSS8,KLK10,GRHL2,NLRX1,ST14,FXYD3,HAL,SDC1,S100A2,CDS1,CTNNBIP1,AIM1L,SCNN1A,CA2,CDH1,LYPD3,BMP7,AIM1,CDH3,TACSTD2,MAST4,CYP26B1,SSH3,SMARCA2,ARAP2,ALDH2,CDA,TFAP2C,COL7A1,ITPR3,NFIB,DUOX1,HLF,ETS2,FGFR2,MATN2,SPINT2,KLF5,KLK7,F2RL1,COBL,ARHGEF4 |
| 2.192e-04 | -8.43 | lateral plasma membrane | cellular component | GO:0016328 | 49 | 14 | 17570 | 1756 |
SNTA1,EPCAM,SCN5A,CDH1,VANGL1,BVES,IQGAP1,CORO1C,TBCD,DLG1,CLDN4,TACSTD2,ERBB3,IQGAP3 |
| 2.195e-04 | -8.42 | regulation of catabolic process | biological process | GO:0009894 | 703 | 101 | 16441 | 1675 |
DLGAP5,THRA,CNOT8,PSME2,CUL4B,TP53,PSME1,BCL2L1,CCNB1,PRKACA,BARD1,APC2,BCAP31,RAD23A,IER3,DAPK2,PSMD1,DACT1,ZFP36,CDKN1B,DAB2IP,TWIST1,CTTN,TIPARP,PLK1,SIRT1,TIMP2,ERLEC1,TRIM8,AKT1,ITCH,PBK,USP18,CDC20,EZR,IDH1,RNF19B,TYSND1,SNX12,CDK1,IRS2,DNM1L,PLK2,NKD1,NRG1,LZTS1,RRAGD,PRKAA2,PINK1,TNRC6C,SCOC,GGA1,DAP,DNAJB2,SOX9,ASB9,PSMD10,TRIB2,PPP2R3A,ADORA1,RNF128,CTSC,PTEN,CST3,BAX,UBE2J1,DAPK1,DRAM1,PLEKHF1,TRIM21,SORL1,BUB1,PIKFYVE,MYLIP,SOCS5,PSMB4,GCLC,NUB1,FURIN,PIP4K2C,PPARA,PRICKLE1,TP53INP2,PSMA4,PLIN5,GPLD1,PRKAG2,TIMP3,SH3BP4,FAM83D,AURKA,CTSA,YOD1,CENPE,FZD5,NDFIP1,UBE2C,TOB1,ESPL1,USP43,EGLN1 |
| 2.201e-04 | -8.42 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP | 28 | 10 | 17758 | 1761 |
ENPP4,DDB2,CA2,FRY,NR4A3,ARFGEF1,BAX,RAB20,MTMR11,CENPN |
| 2.212e-04 | -8.42 | embryonic placenta development | biological process | GO:0001892 | 90 | 21 | 16441 | 1675 |
HES1,GRHL2,CDKN1C,AKT1,EPAS1,ST14,PDGFB,SOCS3,E2F7,NCOA3,HS6ST1,CYR61,FGFR2,GATA2,SPINT2,PLK4,FZD5,E2F8,GAB1,MDFI,EGLN1 |
| 2.213e-04 | -8.42 | maintenance of location | biological process | GO:0051235 | 136 | 28 | 16441 | 1675 |
SUN1,SUN2,LTBP1,GAA,PINK1,NFKBIE,AKT1,ACVR1C,THRA,ASPM,SYNE2,HEXB,PDIA3,PSMD10,EZR,FTH1,DAG1,PLIN5,B4GALNT1,ENPP1,ATP7B,NFKBIA,SORL1,SUN3,TLN2,GM2A,MDFI,KDELR1 |
| 2.215e-04 | -8.42 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | 175 | 33 | 17758 | 1761 |
MAN2B2,DYNLRB1,TPRN,ARHGEF11,UBASH3B,GALNT12,ITGA6,ASAH1,SNN,TRIB2,EPS8L2,C16orf74,ABCA2,CD70,DLG3,CITED2,CLIP2,ALS2CL,C9orf72,SLC16A5,S100A6,PQLC3,KIFC2,MMD,LDB2,RNPEP,FOS,TYSND1,SOCS3,BMP1,NFKBIZ,ZMIZ1,TOB1 |
| 2.215e-04 | -8.42 | GSE29618_BCELL_VS_PDC_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_UP | 175 | 33 | 17758 | 1761 |
PARP12,CKAP2,HLA-F,TSC22D3,PPFIBP2,TRIB2,FAM46C,BMP2K,FAM111A,SP100,PLCG2,CDKN1B,ECE1,PIKFYVE,ATP2B1,TRAK2,HES1,SYPL1,CD55,MMD,EZR,ARHGDIB,CD83,KLHL2,IRS2,SWAP70,BANK1,NFKBIA,RYK,PIK3C2B,NR4A2,TRAF5,KLF7 |
| 2.221e-04 | -8.41 | CYTOSKELETON | MSigDB lists | CYTOSKELETON | 358 | 57 | 17758 | 1761 |
MYL9,BIN1,LASP1,BMF,SORBS1,NF2,DLGAP5,IQGAP1,KIF23,HDAC6,SPTB,APPBP2,SAC3D1,ATG4A,KIF5B,TOP2A,CDH1,CNTRL,CALD1,CABP1,TBCD,NEK2,ABCA2,DAPK1,TUBG1,BUB1,ESPN,EPB41L4B,CTTN,CLIP2,NEB,ATG4D,PLK1,PCGF5,CDC20,UTRN,EZR,ARHGDIB,ANLN,AIF1L,KIF11,CDK1,DAG1,RANBP9,NIN,KLHL2,MAP2,SHROOM3,CORO1C,AURKA,ARPC2,NDE1,CEP41,CCNB2,HSPB1,SHROOM2,ESPL1 |
| 2.249e-04 | -8.40 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | 197 | 36 | 17758 | 1761 |
LAMP1,AASS,DNAJB2,TP53,SELL,PSME1,GRK6,FAM101B,STIM1,KCNN4,TSPAN6,ZFP36,BMP7,LMO4,FOSB,FAM102A,F2R,NR2C1,PGM1,PRSS23,TNIP1,USP18,GLO1,TCF7,SLC11A2,YES1,SESN1,SOCS3,CMTM7,SCARB2,FAAH,MAP2,NFKBIA,MAP3K5,TOB1,XDH |
| 2.249e-04 | -8.40 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | 197 | 36 | 17758 | 1761 |
SCOC,LGALS3,IL15,S100A11,GNPDA1,TMEM41B,PTTG1,EPS8,CRABP2,OAT,IL18R1,PLS3,AIM1,GTF2F2,BAX,TACSTD2,PIM1,PDIA6,S100A6,FAH,GCNT1,IFITM3,USP18,FURIN,GGH,RNF19B,CASP4,ATP13A2,SOCS3,AHRR,GEM,TMEM159,ABCA1,KLF7,EHD1,JARID2 |
| 2.249e-04 | -8.40 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | 197 | 36 | 17758 | 1761 |
ENO2,AASS,PSME2,TSC22D3,SELL,CALM3,TP53I11,SEPP1,DHRS3,S100A2,PDIA4,CALM2,TYMP,ITGA3,RRBP1,TRIM21,FAM102A,CTTN,S100A13,FAH,MX1,AMOTL2,COL6A2,SLC39A8,PLAUR,SAT1,CALM1,OPTN,SERPINA1,ACVRL1,H1F0,PLK2,GDF11,LTA4H,MAFF,IFI6 |
| 2.249e-04 | -8.40 | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | 197 | 36 | 17758 | 1761 |
BIN1,SLC25A24,MRC2,ARMCX3,FAM101B,IER3,IL17RB,ADD3,FUT8,CD9,PIM1,TAGLN2,PHKA2,PTPRE,GM2A,CKAP4,S100A6,IGDCC4,GCNT1,PLSCR1,S100A4,LITAF,CCDC34,MAP3K6,CMTM7,RASGRP2,ATP13A2,ATP1A1,TLE1,EGFL7,LRRK1,ATP1B3,CMPK2,TMEM159,SERPINB1,NRGN |
| 2.249e-04 | -8.40 | HALLMARK_G2M_CHECKPOINT | MSigDB lists | HALLMARK_G2M_CHECKPOINT | 197 | 36 | 17758 | 1761 |
PTTG1,NDC80,KIF23,BARD1,STIL,LBR,CCND1,CDKN2C,KIF5B,TOP2A,SS18,NEK2,PLK4,CDKN1B,BUB1,SLC12A2,CKS2,PLK1,HMMR,CENPA,PBK,CDC20,MYBL2,NUSAP1,CCNF,H2AFV,KIF11,CDK1,RBL1,AURKA,EFNA5,HMGA1,CENPE,CCNB2,UBE2C,ESPL1 |
| 2.249e-04 | -8.40 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | 197 | 36 | 17758 | 1761 |
SUN1,ADD1,IL15,CAMKK1,HLA-E,HDAC11,TAP1,SELL,FAM198B,BEX2,FZD6,CDKN2C,PDGFA,ADD3,RALGPS2,NPNT,TPST1,NTN4,CRY2,MYLIP,SUN2,PRODH,ADCK3,STAT4,PCBP3,ATP8B3,STK17B,GABARAPL1,NR1D2,TWSG1,WBSCR27,PER3,SERPINB1,ABCA1,DCBLD1,MAPK12 |
| 2.311e-04 | -8.37 | CYTOPLASMIC_PART | MSigDB lists | CYTOPLASMIC_PART | 1354 | 173 | 17758 | 1761 |
MYL9,LAMP1,MRPS15,AASS,SLC25A13,DNAJB11,TGOLN2,ITPR2,OAT,DNER,ERP29,SPTB,SLC9A7,ARHGEF10L,CNTRL,STIM1,RGS3,ZFP36,STEAP2,FUT1,TMEM143,ABCA2,TUBG1,TACSTD2,CTTN,TRAM1,NEB,ERAP2,LAMP3,LAMP2,PLK1,PCGF5,SGCE,SNTB2,CDA,EZR,ARHGDIB,ANLN,ICMT,MRPS36,IDH1,POR,OPTN,SLC25A4,AGPAT2,WIPI1,DNM1L,DOLPP1,ATP7B,NOD2,SERPINB6,MRPS28,GLA,ARF6,RAP1GAP,F2RL1,PCSK5,FGD1,LASP1,PEX6,GGA1,SLC25A27,NDUFA4,RAB6A,ATG4A,DOPEY2,NEK2,MPHOSPH9,CCDC88A,KDELR1,KIF20A,RGMB,PDK3,NPC2,STX3,CDK5R1,GLCE,GNAS,AP1AR,FGD6,MDH1,CTSA,PLD1,NDE1,PLIN3,SHROOM2,IFI6,EGLN1,SLC2A4,NF2,DLGAP5,IL15,TP53,PDIA5,BCL2L1,AIFM2,SYTL2,RCN1,CDH1,RPN2,PHKA2,MINPP1,LMAN1,PDIA6,F2R,SCYL3,GPX4,ATG4D,SEMA3B,SEC23A,CLCN3,SEC61B,COG2,ACO1,KIF1C,PKMYT1,ITPR3,NIN,GABARAPL1,TAPBP,IDE,ALDH5A1,DDOST,SLC9A6,PEX2,SECTM1,ANXA9,SYT13,AIFM3,ISOC1,ABCA1,GOLIM4,PINK1,CD63,PDIA3,CTSZ,DSE,NUCB2,AIP,DNAJB9,VPS26A,SAC3D1,PDIA4,TOP2A,KIF5B,FUT2,CTSC,ARSG,RRBP1,BAX,ECI2,TMBIM6,BUB1,SGCB,B3GALT6,SHMT1,NR3C1,AMFR,PIK3R1,FURIN,PRICKLE1,SNTB1,CRISPLD2,NUCB1,ACADSB,PLOD2,ERAP1,PLOD3,CEP41,ARSB,ESPL1,GOLGB1,ABCG1 |
| 2.313e-04 | -8.37 | MARTINEZ_RB1_AND_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_UP | 579 | 84 | 17758 | 1761 |
SLC2A4,SORBS1,ADD1,EPAS1,SLC25A13,PTTG1,TP53,OSR2,DDR1,EMP2,BCAP31,SH3KBP1,IER3,PDGFA,WEE1,NOV,IL6ST,KLF3,CTTN,MARCH2,EGLN3,LMAN1,SULT2B1,CTDSP2,MYO5B,CPD,CAPN6,PBK,ACO1,SLC11A2,GLO1,DPYSL3,IDE,JAK1,HOXA9,BMP1,SLC25A30,LASP1,SORT1,PINK1,MRC2,SCOC,KLHL13,DAP,ERI2,COL4A5,FAM21C,FBLN1,HOXB2,LGALS3BP,SIRPA,SGPL1,ADD3,FUT2,CYR61,DRAM1,FAH,FADS2,PDGFC,KIF20A,NR3C1,ZC3H11A,NR4A1,LITAF,TCF7,AIF1L,KIF11,FOS,NUBP1,TP53INP2,RANBP9,GNAS,FECH,FUCA1,PTPRF,PITX2,TWSG1,FGFR2,ITGAV,PLD1,SERPINB1,HIPK3,AHR,XDH |
| 2.315e-04 | -8.37 | AAGCACT,MIR-520F | MSigDB lists | AAGCACT,MIR-520F | 227 | 40 | 17758 | 1761 |
SPRED1,GRHL2,EPAS1,XYLT1,PBX3,PLXNA1,FAM46C,PPP2R3A,TFAP4,CCND1,UBE2Q2,RALGPS2,IL6ST,FRAS1,LYPD6,LHX6,TUBG1,CDKN1B,IRF2,NTN4,TIPARP,CPD,CYP26B1,ZNF462,PCGF5,TMTC1,ANO6,FNDC3A,NFIB,MUM1L1,ABR,CDK19,RBL1,NR4A3,AGFG2,YOD1,ABCA1,ARHGEF9,RGMA,NR2C2 |
| 2.328e-04 | -8.37 | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDM_UP | 190 | 35 | 17758 | 1761 |
SPRED1,LGALS3,C6orf106,PSMD10,FBXO6,CMTM6,FANCI,TMCC3,RASSF8,CST3,RRBP1,TMEM51,SGK1,IRF2,TMBIM6,TSPAN13,MDFIC,SGCB,TIPARP,RBMS2,SCN3A,DPYSL5,SUN2,PLSCR1,SLC37A1,ITCH,PLEKHO1,SAT1,UTRN,RNF19B,NCOA3,ABCB1,RGS14,NRBP1,JARID2 |
| 2.329e-04 | -8.36 | neuron projection | cellular component | GO:0043005 | 888 | 121 | 17570 | 1756 |
LAMP1,NF2,IQGAP1,EPHA4,RET,FBXO2,NDRG2,LYNX1,HDAC6,PRKACA,DNER,GRM5,NCS1,SH3KBP1,CALM2,NOV,IL6ST,CABP1,DPYSL2,DLG1,DAB2IP,GOT1,MYH14,CTTN,SCN2A,DLG3,PACSIN1,ATL1,ORAI2,SGCE,CLCN3,TIMP2,MBP,S100A4,SEPT6,CCSAP,PRKAR2B,ALCAM,DAG1,ARF4,GABARAPL1,DPYSL3,PIAS3,TRIM9,MAP2,KCNK1,PLK2,WFS1,LIMK1,SLC9A6,SIPA1L1,TMOD2,NRG1,ITPKA,RGS14,NRGN,LZTS1,COBL,BIN1,ANXA3,PINK1,SORT1,LMTK3,CPEB4,CALB2,EPS8,LRP4,CALM3,GABRG2,SLC1A3,CNTNAP2,KIF5B,ITGA3,ADORA1,CA2,MLPH,IGF1R,IGSF9,SNX18,PTEN,CDK16,ANKS1B,FLRT3,KIF13B,CST3,EXOC8,KLC3,AHCY,MYO5A,DPYSL5,RASGRF1,ZWINT,RHOA,RAPGEF2,CALM1,GRIN1,STMN3,ELK1,FOS,NFIB,MAPK8IP1,CDK5R1,STX3,FAS,RASGRP2,GNAS,CNTNAP1,PTPRF,GABRD,SYT7,CTSV,AURKA,ARRB1,GRIN2D,GPER1,ARPC2,SEMA3A,CPEB2,L1CAM,ACOT7,SNPH |
| 2.335e-04 | -8.36 | ENK_UV_RESPONSE_KERATINOCYTE_UP | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_UP | 521 | 77 | 17758 | 1761 |
CCNI,KLK10,S100A11,PSME1,TNFSF9,IER3,ATP6V0B,BTG3,CTGF,ZFP36,AKR1B1,CLDN4,VAT1,TACSTD2,ACOX2,TECR,LGMN,TSPAN1,PTPRE,SULT2B1,GPX4,CTH,PPIF,DRAP1,CDA,STK17B,OVOL1,ZNF165,KLF5,EIF4EBP2,SERPINB6,GLA,HSPB1,F2RL1,MAFF,GRN,PRSS8,CD99,CDKN1C,IGFBP6,DNAJB2,HLA-F,HLA-E,SDC4,BLVRB,CRABP2,GSTP1,EFNB1,HLA-A,SNTA1,CDK16,LYPD3,CYR61,SGK1,TAGLN2,HLA-C,CITED2,SPRY2,TGIF1,PSMB4,HMG20B,FOS,GNAS,GALNT3,NUCB1,RPL12,ETS2,RND3,PVRL2,DHRS2,ITPR1,NR4A2,PLD1,HMGA1,GEM,PLIN3,TOB1 |
| 2.337e-04 | -8.36 | HALLMARK_UV_RESPONSE_UP | MSigDB lists | HALLMARK_UV_RESPONSE_UP | 154 | 30 | 17758 | 1761 |
PPIF,CASP3,ENO2,PPP1R2,CDKN1C,NR4A1,HLA-F,RET,FURIN,TAP1,GGH,SPR,PRKACA,FOS,EPCAM,ONECUT1,BTG3,CYP1A1,CA2,SLC25A4,PDLIM3,NAT1,IL6ST,NFKBIA,FOSB,ABCB1,TMBIM6,IGFBP2,NPTXR,RASGRP1 |
| 2.337e-04 | -8.36 | GTGACTT,MIR-224 | MSigDB lists | GTGACTT,MIR-224 | 154 | 30 | 17758 | 1761 |
AMOTL2,RUNX2,NUAK1,NR4A1,CIT,CAST,MGAT4B,SDC4,KIF23,KCTD12,FTH1,COL7A1,NOTUM,PHLPP1,TRIM9,ITGA3,SLC4A4,RND3,DPYSL2,LYPD6,AMMECR1,FOSB,OTUB2,NR4A2,YOD1,ACSL4,ATP1B3,MYLIP,CBX7,CPEB2 |
| 2.344e-04 | -8.36 | PID_PLK1_PATHWAY | MSigDB lists | PID_PLK1_PATHWAY | 44 | 13 | 17758 | 1761 |
PLK1,WEE1,RHOA,KIF20A,CDC20,NDC80,TUBG1,AURKA,BUB1,CENPE,CCNB1,BORA,CDK1 |
| 2.417e-04 | -8.33 | B41 | smart domains | SM00295 | 51 | 15 | 9131 | 997 |
FRMPD3,EPB41L5,PLEKHH2,JAK1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,JAK3,MYLIP,FARP2,FRMD4B |
| 2.419e-04 | -8.33 | FRASOR_RESPONSE_TO_ESTRADIOL_DN | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_DN | 80 | 19 | 17758 | 1761 |
ANXA3,MMD,GNE,LITAF,ASB9,CBX6,ERBB2,COL4A5,DUSP4,LHFPL2,IER3,GNS,RND3,PLK2,MATN2,ERBB3,RAP1GAP,SLC16A5,ABCG1 |
| 2.437e-04 | -8.32 | SCHLOSSER_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_DN | 681 | 96 | 17758 | 1761 |
SUN1,PLA2G4A,BCAM,NF2,PSME2,THRA,RALBP1,CAST,ATP8A1,HEXB,NDC80,ARFGEF1,PJA2,CALM2,ZFYVE16,BTG3,PSMD1,SP100,IL6ST,ATRNL1,RPN2,RP2,PIK3CD,ACSL4,MINPP1,TRAM1,RASGRP1,CTH,LAMP2,SEC23A,SGCE,CD55,SEC61B,SLC39A8,SEPT6,SAT1,PRKAR2B,GLO1,RAD17,MCFD2,GTF2A2,SLC25A5,ZFAND5,H2AFV,MYL12A,TRIM9,PEX2,LRIG1,PIK3C2B,NRGN,COBL,NXT2,RUNX2,PPP1R2,TBC1D1,GNE,CALM3,PSMD10,CYB561,HMGN3,PHLPP1,COX6C,FBLN1,PSIP1,SIRPA,DOPEY2,ADD3,MEGF8,AIM1,RUNDC3B,UBE2J1,CD9,TFAP2A,PIKFYVE,NCOA2,SYPL1,ARAP2,MMD,MICB,LPGAT1,CALM1,DIAPH2,SPTLC2,PSMA4,DCTN6,ETS2,FGFR2,HNRNPH2,DCK,NMI,RYK,CCDC69,MDH1,CDK18,MAP3K5,TOB1 |
| 2.466e-04 | -8.31 | C2 | prosite domains | PS50004 | 108 | 24 | 11866 | 1235 |
PLA2G4A,MCTP1,ITCH,RASA2,SYTL4,RASA1,SYTL2,ABR,PLCG1,CPNE2,PLCH1,SYT7,RAB11FIP2,RGS3,RIMS3,PLCG2,RAB11FIP1,WWP1,PIK3C2B,SYT13,PLCB2,SYTL3,RIMS2,ESYT2 |
| 2.470e-04 | -8.31 | MAPK family signaling cascades | REACTOME pathways | R-HSA-5683057 | 273 | 48 | 8202 | 867 |
SPRED1,TNRC6C,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PRKACA,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,IL6ST,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,ETV4,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,AGO4,DUSP4,CDK1,PSMA4,RASA1,IRS2,NCOA3,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,HSPB1,JAK3 |
| 2.472e-04 | -8.31 | V$NKX22_01 | MSigDB lists | V$NKX22_01 | 176 | 33 | 17758 | 1761 |
CPEB4,HOXB7,NUAK1,THRA,ETV5,SH3KBP1,ZFYVE9,NRP2,SYTL2,NEO1,CCDC92,CDKN2C,FOXP2,C16orf74,RGS3,LMO4,BHLHE41,SLC44A1,MDFIC,ZRANB1,TIAM1,CITED4,PBK,PIK3R1,PIP4K2C,KIF13A,KDM4D,NFIX,HNRNPH2,ITPR1,PPP2R3C,GLA,NDFIP1 |
| 2.502e-04 | -8.29 | oxoacid metabolic process | biological process | GO:0043436 | 984 | 134 | 16441 | 1675 |
ACACB,SLC35D2,UGT8,HSPG2,AASS,CRYM,CPT2,HEXB,VARS2,OAT,SDC1,CHPF,CYP1A1,CYP2S1,IMPAD1,ALDH1A3,PAPSS1,SERINC2,ACOX2,TECR,CYP1B1,PRKAR2B,ICMT,IDH1,MRPS36,CYP4F3,POR,HS6ST1,ENPP1,HPSE,UEVLD,P4HA2,DHTKD1,ADIPOR1,PRKAA2,FAM213B,ALDH6A1,SLC1A3,B4GALT4,GNS,PCYOX1,AHCY,GAD1,MCCC2,ABCC1,CYP26B1,GFPT1,CHSY3,FADS2,B3GNT7,PRODH,ERO1A,PDK3,AMDHD1,CYB5A,GLCE,MAPKAPK2,SLC6A6,PRKAG2,FAAH,MDH1,EGLN1,PLA2G4A,UGP2,PAPSS2,XYLT1,MGST2,SLC7A2,LPIN3,CYP39A1,CYP26A1,XYLT2,FABP6,SRR,GOT1,ACSL4,MINPP1,EGLN3,SULT2B1,SULF2,GPX4,CTH,PANK1,ACO1,GLO1,ALDH5A1,ABHD12,PEX2,SLC27A1,CYP2U1,HS3ST3B1,ST3GAL1,SLC27A3,LTA4H,NDST3,CMAS,GCLM,ENO2,GNE,SDC4,HAL,DSE,CRABP2,SPR,SGPL1,SLC27A6,GALNS,ECI2,ATP8B1,ABCD1,ALDH7A1,SYK,MYO5A,CRTAP,NCOA2,FAH,B3GALT6,PGM1,B3GNT2,SHMT1,PLSCR1,GCLC,ELOVL3,PPARA,OGDHL,GGH,RNPEP,PRDX4,ACADSB,NR4A3,ARSB,PTGES,ACOT7,OCLN |
| 2.503e-04 | -8.29 | C11orf65 (chromosome 11 open reading frame 65) | protein interactions | 160140 | 7 | 5 | 16036 | 1726 |
CALM2,CALM3,LASP1,UBE2T,CALM1 |
| 2.530e-04 | -8.28 | WANG_LMO4_TARGETS_UP | MSigDB lists | WANG_LMO4_TARGETS_UP | 336 | 54 | 17758 | 1761 |
GRN,LTBP1,BCAM,CPEB4,DCAF7,RET,C5orf30,CYB561,F11R,PM20D2,DNAH3,EMP2,BCAP31,WWP2,SUSD2,WEE1,ANKS6,RALGPS2,SNX18,SLC16A6,BMP7,DLG1,SGK3,BCL6,PCYOX1,IGFBP2,AHCY,TIAM1,TIPARP,S100A13,MAP3K3,SYPL1,FBXL16,AKT1,RGMB,SERTAD4,LPGAT1,MBNL3,LITAF,HMG20B,TFAP2C,CDCA2,ATP1B1,ETS2,SYT7,DHRS2,DBI,PGRMC1,PITPNA,TMEM120A,ZMIZ1,CAPN1,PROM2,NR2C2 |
| 2.534e-04 | -8.28 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | 169 | 32 | 17758 | 1761 |
UBASH3B,TSC22D3,EPHA4,SYTL2,DNAJB9,OTUD1,ABCA2,SGK1,PDE4D,CITED2,MYLIP,C9orf72,SLC16A5,SMAGP,SUSD3,KIFC2,ITCH,COQ10B,SAT1,DIAPH2,FOS,SOCS3,IRS2,PTPRJ,PELI2,CCDC69,NR4A2,YOD1,RELL1,TOB1,MAFF,KLF7 |
| 2.543e-04 | -8.28 | NCAM signaling for neurite out-growth | REACTOME pathways | R-HSA-375165 | 266 | 47 | 8202 | 867 |
SPRED1,COL9A3,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,COL4A5,PSME1,CACNB4,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,ARTN,SHC3,COL6A1,DUSP10,DAB2IP,ERBB3,CACNA1D,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,COL6A2,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 2.551e-04 | -8.27 | BURTON_ADIPOGENESIS_PEAK_AT_2HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_2HR | 50 | 14 | 17758 | 1761 |
WEE1,CTGF,ETS2,CYR61,NR4A1,ZFP36,FOSB,NR4A2,PIM1,FOS,PHLDA1,SLC20A1,CAPN1,IER3 |
| 2.551e-04 | -8.27 | DAUER_STAT3_TARGETS_DN | MSigDB lists | DAUER_STAT3_TARGETS_DN | 50 | 14 | 17758 | 1761 |
DDX58,MX1,PARP12,TRANK1,USP18,HERC5,IRF7,SAMD9,IFIT1,OAS3,IFIT3,HERC6,IFIH1,LAMP3 |
| 2.552e-04 | -8.27 | FERM_central | interpro domains | IPR019748 | 50 | 14 | 18293 | 1814 |
FRMPD3,EPB41L5,PLEKHH2,JAK1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 2.552e-04 | -8.27 | BARRIER_COLON_CANCER_RECURRENCE_DN | MSigDB lists | BARRIER_COLON_CANCER_RECURRENCE_DN | 19 | 8 | 17758 | 1761 |
NUCB1,CTSA,AES,HLA-C,ASB13,CITED2,NDFIP1,TSPAN7 |
| 2.552e-04 | -8.27 | HU_ANGIOGENESIS_UP | MSigDB lists | HU_ANGIOGENESIS_UP | 19 | 8 | 17758 | 1761 |
PRODH,RND3,SIPA1L1,PIK3R1,COL7A1,NRGN,FOS,FAH |
| 2.552e-04 | -8.27 | BIOCARTA_GCR_PATHWAY | MSigDB lists | BIOCARTA_GCR_PATHWAY | 19 | 8 | 17758 | 1761 |
GNAS,CALM2,AKT1,NR3C1,CALM1,PIK3R1,PIK3CA,CALM3 |
| 2.552e-04 | -8.27 | DELLA_RESPONSE_TO_TSA_AND_BUTYRATE | MSigDB lists | DELLA_RESPONSE_TO_TSA_AND_BUTYRATE | 19 | 8 | 17758 | 1761 |
RHOA,GATA2,NR4A1,CDC20,HSPB1,DDR1,POR,TOB1 |
| 2.553e-04 | -8.27 | early endosome | cellular component | GO:0005769 | 287 | 48 | 17570 | 1756 |
SORT1,PACSIN2,NF2,ATP9A,HLA-E,HLA-F,EPHA4,RET,CNTNAP2,MVB12B,FAM21C,DNER,PARM1,VPS26A,ZFYVE9,HLA-A,MARCH8,ZFYVE16,KIAA0319,STEAP2,SGK3,SNX16,SORL1,RAB20,ECE1,HLA-C,PIKFYVE,WNT3A,F2R,MYO5A,TRAK2,CLCN3,DIAPH2,SLC11A2,RAB38,NEURL1B,SNX12,HLA-B,NUCB1,AP1AR,SLC9A6,GPER1,FZD5,ARF6,F2RL1,NIPA1,RUSC1,EHD1 |
| 2.563e-04 | -8.27 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 352 | 56 | 17758 | 1761 |
GCLM,PACSIN2,PAPSS2,IGFBP6,RALBP1,DCAF7,NCKAP1,LBR,CMTM6,VPS26A,DNAJB9,NEO1,TOP2A,APLP2,TNS3,IL6ST,CST3,EXOC8,TMBIM6,RPN2,CTTN,EGLN3,ALDH3A2,GM2A,CTH,SEC61B,AKT1,AMFR,LITAF,PTGFRN,KIF11,POR,FUCA1,PTPRF,NUCB1,SLC6A6,IDE,PTPRJ,TIMP3,SLC4A4,DDOST,MAP2,NR1D2,SCG2,STK38,SIPA1L1,DBI,ITPR1,PITPNA,SLC27A1,NRG1,NR4A2,STK39,LTBP2,HOOK1,AHR |
| 2.584e-04 | -8.26 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | 191 | 35 | 17758 | 1761 |
TXN,UGP2,NFKBIE,ENO2,TRIP10,ARL4C,SELL,IER3,TYMP,LYPD3,AKR1B1,DOCK4,PGM1,TNIP1,SLC39A8,ACO1,LITAF,AK4,ELK1,RNF19B,CYB5A,OPTN,CD83,ETS2,FGFR2,RND3,H1F0,PVRL2,SPINT2,IRF7,GEM,UNC5B,TBC1D4,EHD1,ARHGEF4 |
| 2.584e-04 | -8.26 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 191 | 35 | 17758 | 1761 |
ARHGEF3,PINK1,ALDH6A1,CAST,UBASH3B,HAL,SELL,IL27RA,MGST2,NUCB2,TRIB2,SNN,FAM101B,PARM1,AP1M2,IL6ST,SLC44A1,UBE2J1,ERBB3,DOCK4,MBP,ADCK3,ACVR1C,CD40,SESN1,NFIX,STK38,LRIG1,SH3BGRL2,USF2,CBX7,SNX30,KLF7,TMEM131,ARHGEF4 |
| 2.586e-04 | -8.26 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | 162 | 31 | 17758 | 1761 |
MYL9,GLIS3,CTHRC1,TIMP2,CCDC109B,MMD,SERPINE2,LGALS3,STAT4,SEPT6,HAL,FURIN,CDA,KCTD12,GALNT7,SLC7A2,EPHA1,SOCS3,CXCL16,ETS2,CDH1,FGFR2,TPST1,GOT1,ACSL4,MAL2,GEM,MAP3K5,RAB27B,SLC12A2,RASGRP1 |
| 2.594e-04 | -8.26 | regulation of microtubule-based process | biological process | GO:0032886 | 151 | 30 | 16441 | 1675 |
PLK1,LAMP1,GAS2L1,CAMSAP3,RHOA,TACC1,CKAP2,CCSAP,STMN3,ERBB2,CCNF,CCNB1,HDAC6,NUBP1,BORA,KIF11,BBS2,APC2,CDK5R1,MID1IP1,PLK2,TBCD,NEK2,PLK4,AURKA,CDKN1B,EFNA5,DIXDC1,CFAP20,WNT3A |
| 2.596e-04 | -8.26 | Synthesis of IP3 and IP4 in the cytosol | REACTOME pathways | R-HSA-1855204 | 27 | 10 | 8202 | 867 |
CALM2,PLCH1,PLCG1,PTEN,INPP5D,PLCG2,CALM1,CALM3,ITPKA,PLCB2 |
| 2.616e-04 | -8.25 | response to oxygen-containing compound | biological process | GO:1901700 | 1463 | 189 | 16441 | 1675 |
CASP3,TXN,SSH1,RET,NRG2,PSME1,IL18,ITPR2,CCNB1,HDAC6,PDGFB,SDC1,SPTB,CALM2,CYP1A1,SESN3,PSMD1,RPS6KA2,CTGF,SHC3,DPYSL2,KLF3,FOSB,PIK3CA,AKR1B1,CLDN4,DUSP10,RASGRP1,CYP1B1,ACVR1C,CASP9,EZR,PRKAR2B,POR,RHEB,ABR,ENPP1,MAP2,NOD2,CAB39,EIF4EBP2,GAB1,RRAGD,PRKAA2,GRN,RASA2,DGKQ,SOX9,CALM3,TFAP4,IGF1R,COL6A1,PIM1,NCAM1,WNT3A,MICB,OXR1,CALM1,ERO1A,STRADB,PDK3,ELK1,PSMA4,RASA1,FAS,FECH,GNAS,MMP15,MAPKAPK2,NCOA3,PRKAG2,NFKBIA,SH3BP4,AURKA,NR4A2,MAP3K5,JAK3,COL16A1,RARG,EGLN1,SPRED1,SORBS1,SLC2A4,NQO1,FOXM1,IL15,PSME2,ERBB2,COL18A1,BCL2L1,PRKACA,PDGFA,CCND1,ATP6V0B,CDH1,SP100,PLCG2,SRR,CDKN1B,DAB2IP,GOT1,PDE4D,LRP11,RASGEF1A,CDKN2D,F2R,FRS3,SIRT1,PPIF,COL6A2,RIPK2,AKT1,FZD4,PTGER4,PRKCQ,ERBB2IP,CD40,DAG1,CASP4,FZD7,SOCS3,IRS2,DUOX1,IDE,ATP1A1,JAK1,CDK19,STK26,AXL,PTK7,SLC27A1,NRG1,SPTBN5,LTA4H,ABCA1,NKX3-1,SORT1,CPEB4,EPS8,PSMD10,SELL,TGFBR1,ETS1,GSTP1,FGF19,HDAC9,CXCL16,PTEN,BMP7,CST3,TFAP2A,BAX,CD9,TMBIM6,IGFBP2,KLF9,ERBB3,MYO5A,GCNT1,PDGFC,RASGRF1,RHOA,SHMT1,PSMB4,RAPGEF2,NR4A1,PIK3R1,GRIN1,LITAF,PPARA,GGH,YES1,FOS,BCAR1,GPLD1,TIMP3,FGFR2,RAB11FIP2,CTSV,NR4A3,OSER1,GRIN2D,GPER1,HOXB13,CMPK2,OSR1,TBC1D4,CPEB2,PTGES |
| 2.652e-04 | -8.24 | cerebral cortex development | biological process | GO:0021987 | 104 | 23 | 16441 | 1675 |
EMX1,RHOA,ADGRG1,TACC1,ASPM,GRIN1,TFAP2C,CNTNAP2,BBS2,CDK5R1,FOXP2,MDK,FAT4,KIF14,LHX6,BAX,DIXDC1,DAB2IP,ZBTB18,WDR62,NDE1,SEMA3A,BTBD3 |
| 2.653e-04 | -8.23 | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | MSigDB lists | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | 100 | 22 | 17758 | 1761 |
MYL9,GAA,BCAM,COL6A2,RPS6KA1,UBE2A,AES,EPHA1,PRKACA,EFNB1,LTBP3,NRP2,WWP2,FECH,PTPRF,ATP6V0B,PDLIM3,ACADSB,BMP1,ACSL4,FHL1,COL16A1 |
| 2.657e-04 | -8.23 | GNF2_FEN1 | MSigDB lists | GNF2_FEN1 | 56 | 15 | 17758 | 1761 |
HMMR,TOP2A,ZWINT,DLGAP5,FOXM1,NDC80,PLK4,NUSAP1,CCNB2,KIF11,CDK1,E2F8,FANCI,METAP2,CKS2 |
| 2.660e-04 | -8.23 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | MSigDB lists | PID_ECADHERIN_NASCENT_AJ_PATHWAY | 39 | 12 | 17758 | 1761 |
CCND1,RHOA,AKT1,CDH1,IQGAP1,PIK3R1,DLG1,PIK3CA,NCKAP1,CTTN,ARF6,TIAM1 |
| 2.660e-04 | -8.23 | DORN_ADENOVIRUS_INFECTION_32HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_32HR_DN | 39 | 12 | 17758 | 1761 |
BCAR3,CCND1,CYR61,RND3,NR4A1,PLK2,NFKBIA,SGK1,TNFRSF12A,COL7A1,IER3,CD83 |
| 2.660e-04 | -8.23 | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | 39 | 12 | 17758 | 1761 |
FECH,ITGA7,CDC20,MYBL2,NFE2L1,UBE2A,ERBB2,IL18,ELK1,F2R,CDKN2D,SPRY2 |
| 2.670e-04 | -8.23 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 221 | 39 | 17758 | 1761 |
CCNE2,SLC25A24,LRRFIP2,CD82,BLVRB,RET,SYTL4,PHLDA1,IL17RB,TFAP4,B3GALNT1,SGK3,OPN3,SGK1,FAM102A,OSTF1,TMEM64,MYBL1,TIAM1,TIPARP,ALDH3A2,SEMA3B,PPIF,PRSS23,CELSR2,SYBU,ASB13,COL12A1,PRIM1,ENDOD1,TMEM164,PLOD2,RBL1,ZNF367,LRIG1,ANXA9,GLA,PTGES,ISOC1 |
| 2.672e-04 | -8.23 | small molecule metabolic process | biological process | GO:0044281 | 2269 | 279 | 16441 | 1675 |
SLC35D2,ACACB,GAA,TXN,HSPG2,AASS,AK7,SLC25A13,HEXB,CACNA2D2,MMADHC,PSME1,OAT,CA8,CALM2,TYMP,CYP1A1,PSMD1,CTGF,CYP2S1,ALDH1A3,KCNS3,SERINC2,PIK3CA,FUT1,AOX1,PIK3CD,ACOX2,APOBEC3G,CDA,PRKAR2B,ICMT,SLC25A5,TP53I3,CYP4F3,POR,ENPP1,PLCG1,SLC25A4,BMP1,DHTKD1,ITPKA,ALDH6A1,SLC25A27,NDUFA4,ISYNA1,SLC1A3,COX6C,GNS,ATP5H,BDH1,PCYOX1,SORL1,CACNA1D,PIKFYVE,NDUFA12,NUP85,MCCC2,GFPT1,FADS2,PMPCB,B3GNT7,PRODH,ADCK3,LPGAT1,CALM1,ERO1A,NPC2,PCTP,SPTLC2,PSMA4,CYB5A,PRKAG2,FAAH,DCK,ITPR1,MDH1,NUP58,XDH,EGLN1,PLA2G4A,MTM1,SLC2A4,NQO1,PAPSS2,INPP5D,IQGAP1,MGST2,PRKACA,CYP39A1,CDS1,APLP2,XYLT2,PDE4D,ACSL4,PHKA2,LGMN,DLG3,SULT2B1,GPX4,ENPP4,SEC23A,CYB5R2,SAT1,PANK1,ATP1B1,ITPR3,IRS2,ALDH3B1,INPP4B,PNPLA6,SLC27A1,HS3ST3B1,SLC27A3,SDC4,APOBEC3H,SPR,GSTP1,SGPL1,FUT2,SLC27A6,ARSG,PTEN,FUT8,ATP8B1,ECI2,SLC44A2,CRTAP,NCOA2,OPLAH,ALDH2,B3GNT2,SHMT1,PLSCR1,MPP1,PIK3R1,ELOVL3,AK4,BLVRA,ARSK,CPTP,GPLD1,ACADSB,DBI,ABCB1,NR4A3,PGM2L1,CMPK2,ARSB,OCLN,ACOT7,NMRK1,UGT8,CRYM,CPT2,VARS2,ITPR2,SDC1,CACNB4,ABCD4,CHPF,GRHL1,IMPAD1,SLC44A1,PAPSS1,DLG1,AKR1B1,TECR,CYP1B1,IDH1,MRPS36,MAN2A2,HS6ST1,PLCH1,NEIL1,AGPAT2,HPSE,UEVLD,P4HA2,PIK3C2B,ADIPOR1,GLA,PRKAA2,FAM213B,ABCG2,ASAH1,CALM3,B4GALT4,DHRS3,CA2,AHCY,FAR2,GAD1,PLCB2,ALDH3A2,ABCC1,CYP26B1,CHSY3,PDE5A,PDK3,NUBP1,AMDHD1,GLCE,MAPKAPK2,GNAS,FECH,ONECUT1,NUDT16,SLC6A6,PLPP3,PRPS2,CTSA,PLD1,APOL2,UGP2,PSME2,XYLT1,SLC7A2,LPIN3,CYP26A1,CYP4F11,FABP6,PLCG2,SRR,GOT1,EGLN3,MINPP1,GM2A,CTH,CHP1,SULF2,AKT1,FIGNL1,ACO1,GLO1,DUOX1,ALDH5A1,ABHD12,PEX2,CYP2U1,LTA4H,ST3GAL1,NDST3,ABCA1,MAN2B2,GCLM,CMAS,ENO2,GNE,BLVRB,HAL,PSMD10,CRABP2,DSE,LBR,ZDHHC21,GALNS,ABCD1,ALDH7A1,SYK,MYO5A,FAH,B3GALT6,HMMR,PGM1,PSMB4,GUSB,GCLC,OGDHL,PPARA,NADK2,GGH,RNPEP,LEPR,PRDX4,FUCA1,NAT1,PTGES,ABCG1 |
| 2.672e-04 | -8.23 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | 184 | 34 | 17758 | 1761 |
TTC8,BIN1,PINK1,ITGA6,SWI5,PKP2,GTF3A,FBXO6,ETS1,PRKACA,VPS26A,APOBEC3B,SESN3,SH3BP1,RINL,RUNDC3B,KLC3,CCDC82,RP2,IFIT1,PIK3CD,MARCH2,LRIF1,C12orf75,RASGRP1,SSH3,GLO1,ASB13,NEIL1,SPINT2,ABCB1,IRF7,SERPINB6,TMEM14A |
| 2.672e-04 | -8.23 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | 184 | 34 | 17758 | 1761 |
BIN1,ENO2,FAM169A,GALNT12,RASA2,ITGA6,NUCB2,TRIB2,AIP,LTBP3,DENND2D,TMEM63A,MGAT4A,PASK,FAM102A,MYLIP,MPHOSPH9,SYNE2,PRKCQ,YES1,ITPR3,SESN1,PLCG1,NGFRAP1,AMMECR1,LRIG1,INPP4B,SLC25A38,TRAF5,TBC1D4,TMEM14A,NR3C2,PKIA,DOCK9 |
| 2.679e-04 | -8.23 | PID_IL4_2PATHWAY | MSigDB lists | PID_IL4_2PATHWAY | 62 | 16 | 17758 | 1761 |
AKT1,INPP5D,PIK3R1,IL13RA1,GTF3A,BCL2L1,ETS1,SOCS3,IRS2,JAK1,BCL6,PIK3CA,HMGA1,JAK3,MYBL1,SOCS5 |
| 2.680e-04 | -8.22 | MULLIGHAN_NPM1_SIGNATURE_3_UP | MSigDB lists | MULLIGHAN_NPM1_SIGNATURE_3_UP | 321 | 52 | 17758 | 1761 |
PLA2G4A,UNKL,ARHGAP11A,PINK1,LGR4,IL15,ARHGEF11,CENPI,DNAJB2,RASSF7,CTDSPL,C5orf30,PBX3,COL4A5,B4GALT4,SEPP1,ARHGEF40,HOXB2,TNS3,FRY,METTL7A,IQCE,KCNS3,BAX,GOT1,WWP1,OSTF1,SGCB,SNX10,DGKG,NCOA2,CTH,METAP2,WBP5,PIP4K2C,ACO1,RAB38,EPHA1,RHEB,CDK5R1,SOX13,PIAS3,MAN2A2,NCOA3,IDE,NGFRAP1,DCK,HOXA9,AGBL5,MAP3K5,TMEM14A,DOCK9 |
| 2.681e-04 | -8.22 | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 87 | 20 | 17758 | 1761 |
LOC81691,CDKN1C,ATP9A,ARL4C,TP53,EZR,TP53I11,NPC2,DHRS3,CASP4,CARD10,STK17A,PDLIM3,ITGA3,AXL,DAPK1,SH3BP4,PIK3CD,GEM,PTPRE |
| 2.701e-04 | -8.22 | embryonic epithelial tube formation | biological process | GO:0001838 | 124 | 26 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SOX9,SDC4,RET,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,SOX8,OSR1,COBL,RARG,DVL2 |
| 2.704e-04 | -8.22 | TGCCAAR_V$NF1_Q6 | MSigDB lists | TGCCAAR_V$NF1_Q6 | 683 | 96 | 17758 | 1761 |
TTC39B,CAMKK1,ERBB2,NDRG2,PRKACA,SYTL2,PLS3,CALM2,CDKN2C,FAM46A,ARTN,STIM1,DACT1,TSPAN6,LMO4,MITF,ANKFN1,BCL6,ANKRD12,GOT1,ARL4D,DLG3,SNX10,ETV4,ZNF462,SMARCA2,CD55,TRIM8,FZD4,ACO1,KIF13A,ROR1,DUSP4,NFIX,IRS2,KLF12,PTK7,SP6,LIFR,NR3C2,RMND5A,FBLIM1,IGFBP6,LRRFIP2,CPEB4,SCOC,ESRP1,ETV5,MIER3,CALM3,C6orf106,DHRS3,SRPX2,TSPAN7,H1FX,LMNA,NRP2,MECOM,FOXP2,ADD3,CYR61,CALD1,KIF13B,FLRT3,FAM13B,RRBP1,CACNA1D,NCAM1,CITED2,MAST4,RBMS2,CKAP4,AMOTL2,PLEKHA6,RC3H2,CALM1,VWA1,RANBP9,NFIB,GPLD1,KLHL2,XKRX,PITX2,AP1AR,TIMP3,SMTNL2,TIMM8A,H1F0,MFSD2A,ITGA7,LTBP2,LRRK1,PER3,OSR1,KLF7,XDH |
| 2.705e-04 | -8.22 | cervix | COSMIC cancer mutations | cervix | 12381 | 1287 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,DPP8,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,TMEM151A,TFAP2C,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,NOD2,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,FAM21C,HPCAL4,RABGGTA,FRY,PAIP2B,ATP5H,MEGF8,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,DGKG,ULBP2,NUP85,PPP6R1,HPS3,PQLC3,ELK1,NPHP3,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,SEPT6,DNAJB14,GTF2A2,ZNF618,GABARAPL1,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,KLC3,ZFAND4,FAM102A,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,CNTNAP1,RPL12,RAB11FIP2,SYT7,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,AGPAT2,ARRDC1,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,AHCY,SELK,PIM1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,TMX4,TP53,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,PINK1,CDH22,CPEB4,KLHL13,HAL,ERI2,GTF3A,AIP,LBR,PARM1,H1FX,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,TFAP2A,GTF2F2,TRIM21,TSPAN13,SYK,ATP2B1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,SSH1,TSC22D3,CAMK1D,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,TACSTD2,ARMCX6,ACVR1C,SLC35C1,KIF13A,LDB2,PRIM1,ANKRD10,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,ADCK2,TPST1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,ATP8B3,ANTXR1,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,RALBP1,DDIT4L,ATP2C2,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,ACAP2,TRANK1,EPHB4,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TRIOBP,SLC27A3,PRR15,CBX7,HAPLN3,CENPI,EPS8,HERC5,PBX3,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,UGT8,VARS2,MPP5,ERP29,TRIM68,HTR1D,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,LAMP3,ITCH,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,C3orf58,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,LMO7,DYNLRB1,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,DIXDC1,EPB41L4B,SEPHS1,PTPRU,C3orf52,CD40,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,ADD1,IL15RA,MRPS15,AASS,DNAJC3,CACNA2D2,DHX8,NRG2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,SERTAD4,LOXL2,F12,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,ARF6,E2F8,GAB1,ALDH6A1,MERTK,LMNA,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SETD3,ITPR1,AURKA,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,ZNF385B,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,SYNE2,NUSAP1,CDCA2,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,GSTP1,ETS1,HOXB2,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ALG13,CALD1,ADAM15,ECI2,MAPK11,NPTXR,SGCB,TPCN1,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,GRIN1,MYEOV,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,MYL9,UNKL,SIGIRR,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,NDC80,TP53I11,HDAC6,SDC1,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,IDH1,ZBTB7B,DPYSL3,PLCH1,MFAP3L,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,ABRACL,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,SCN2A,DVL2,GM2A,CPD,SIRT1,TMTC1,CDC20,MYL12A,DUOX1,DNAJC10,PRRT4,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,CD63,MACC1,RUSC2,GNE,GABRG2,PSMD10,SELL,NKRF,DSE,SIRPA,SLC9A2,PPP2R3A,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,BANK1,FAT4,SERPINA1,ZNF214,NAT1,TMC5,CDCA7L,NMI,NETO2,PGRMC1,FAM117A,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,SESN3,CTGF,ELMO2,ZFP36,IQCE,PRICKLE3,RGS3,IL31RA,AOX1,ATRNL1,MTMR11,RCAN3,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SLC25A5,ZFAND5,TP53I3,SPNS3,AHRR,PTER,GNPTAB,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,KIF23,ISYNA1,SLC1A3,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,BDH1,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,DDB2,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,DCK,SLC4A3,FGD6,PCDH19,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,ARMCX3,TRIP10,NLRX1,CAST,IQGAP1,BROX,KCTD12,RNF182,CD274,SNN,MNS1,APLP2,ZNF75D,FAM46A,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,CCNJL,APOBEC3H,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,MPP1,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,PGM2L1,GRIN2D,SLC25A38,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,CPT2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,RAB20,RP2,MYH14,SLC39A10,RASGRP1,ATL1,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,LRRC42,ZNF114,ARHGEF19,UEVLD,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,OTUD1,AIM1L,CA2,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,SLC6A6,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,EGFL7,PITPNA,PROM2,GAS2L1,SLC25A24,IL15,MORC4,TDRKH,ARHGEF16,LRRC45,SETDB2,ZDHHC12,FRYL,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,PEX2,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,ASPM,DEPDC4,LRRC66,OGDHL,KLHL2,HLA-B,PRCP,HNRNPH2,GEM,L1CAM,SNPH |
| 2.724e-04 | -8.21 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 326 | 56 | 16036 | 1726 |
DDX58,SORBS1,TRIP10,THRA,IQGAP1,RET,EPHA4,EPS8,TP53,ERBB2,PRKACA,ETS1,EFNB1,HLA-A,SH3KBP1,SLC9A2,IGF1R,ADRBK1,CDH1,SH3BP1,DOK4,ADAM15,CDKN1B,OSTF1,CTTN,ERBB3,PDE4D,TIAM1,PTPRE,SYK,FARP2,THRB,RASGRF1,PLSCR1,AKT1,NR3C1,PIK3R1,PTGER4,BCAR1,DAG1,RASA1,ARHGAP35,EDNRA,CNTNAP1,HLA-B,PLCG1,ETS2,MAP2,AXL,NFKBIA,ARRB1,EFNA5,PLD1,AFAP1,CD33,EGLN1 |
| 2.729e-04 | -8.21 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 337 | 54 | 17758 | 1761 |
MYL9,MRC2,KIAA1462,SERPINE2,NUAK1,XYLT1,ETV5,ARL4C,LMCD1,KCTD12,IL18,DSE,ARHGEF40,MERTK,SRPX2,PLS3,TNS3,CTGF,CYR61,CALD1,DACT1,PLCG2,COL6A1,FXYD5,AKR1B1,SGK1,TRPC1,TWIST1,ACSL4,F2R,SGCB,SEC23A,CD55,COL6A2,ELK3,TACC1,S100A4,PLAUR,ROR1,LOXL2,LDB2,TP53I3,ATP10D,CRISPLD2,EDNRA,FAS,DPYSL3,TIMP3,ANKRD6,AXL,SLC9A6,PRKCDBP,GEM,COL16A1 |
| 2.742e-04 | -8.20 | steroid hormone receptor activity | molecular function | GO:0003707 | 55 | 15 | 16491 | 1673 |
THRB,NKX3-1,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,GPER1,NR3C2,NR2C1,RARG,PAQR7,NR2C2 |
| 2.744e-04 | -8.20 | PI3K/AKT activation | REACTOME pathways | R-HSA-198203 | 101 | 23 | 8202 | 867 |
TNRC6C,RHOA,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 2.746e-04 | -8.20 | glutamate metabolic process | biological process | GO:0006536 | 28 | 10 | 16441 | 1675 |
GCLM,PRODH,ALDH5A1,GCLC,HAL,GOT1,SLC1A3,OAT,GAD1,AMDHD1 |
| 2.746e-04 | -8.20 | heparan sulfate proteoglycan metabolic process | biological process | GO:0030201 | 28 | 10 | 16441 | 1675 |
B3GALT6,HS6ST1,HPSE,XYLT2,XYLT1,HS3ST3B1,DSE,NDST3,SULF2,GLCE |
| 2.760e-04 | -8.20 | V$TEF_Q6 | MSigDB lists | V$TEF_Q6 | 244 | 42 | 17758 | 1761 |
LMO7,SPRED1,CAST,ETV5,C5orf30,SLC20A1,HOXB2,HPCAL4,GRM5,NEO1,CCND1,IGF1R,RALGPS2,FRY,GRHL1,DPYSL2,RGS3,ALG13,KCNS3,TWIST1,CACNA1D,SCN2A,SPRY2,DOCK4,TRIM8,USP18,CBX6,ARHGDIB,NFIX,DHX32,NIN,DNAJC10,PDLIM3,KLF12,GPRC5B,WIPI1,COL13A1,MAP2,PELI2,MAL2,NDFIP1,TOB1 |
| 2.776e-04 | -8.19 | carcinoma_in_situ | COSMIC cancer mutations | carcinoma_in_situ | 94 | 21 | 17775 | 1757 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,PKN1,IDH1,MAP3K6,GNA11,GNAS,EPHA10,JAK1,CDH1,PTEN,FGFR2,PIK3CA,JAK3 |
| 2.776e-04 | -8.19 | ductal_carcinoma_in_situ | COSMIC cancer mutations | ductal_carcinoma_in_situ | 94 | 21 | 17775 | 1757 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,PKN1,IDH1,MAP3K6,GNA11,GNAS,EPHA10,JAK1,CDH1,PTEN,FGFR2,PIK3CA,JAK3 |
| 2.776e-04 | -8.19 | breast-carcinoma_in_situ-ductal_carcinoma_in_situ | COSMIC cancer mutations | breast-carcinoma_in_situ-ductal_carcinoma_in_situ | 94 | 21 | 17775 | 1757 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,PKN1,IDH1,MAP3K6,GNA11,GNAS,EPHA10,JAK1,CDH1,PTEN,FGFR2,PIK3CA,JAK3 |
| 2.789e-04 | -8.18 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | 107 | 23 | 17758 | 1761 |
ARHGEF3,ST14,SOX9,F11R,NTAN1,DDR1,LBR,LMNA,TMEM63A,SOX13,PDGFA,NCOA3,ST5,TJP3,LLGL2,CDK19,MATN2,SPINT2,ZNF165,EPHB4,CACNA1D,ATP2B1,SEPHS1 |
| 2.789e-04 | -8.18 | DOANE_BREAST_CANCER_ESR1_UP | MSigDB lists | DOANE_BREAST_CANCER_ESR1_UP | 107 | 23 | 17758 | 1761 |
SSH3,RET,SYBU,GDF15,GALNT7,DUSP4,ALCAM,SCNN1A,TJP3,ACADSB,MLPH,DHRS2,SLC16A6,NAT1,TMC5,INPP4B,ANXA9,ACOX2,CACNA1D,TSPAN1,MAST4,CYBRD1,SEMA3B |
| 2.794e-04 | -8.18 | TAGCTTT,MIR-9 | MSigDB lists | TAGCTTT,MIR-9 | 229 | 40 | 17758 | 1761 |
CDK17,CPEB4,CIT,LRP4,NKRF,MPP5,ZNF385B,KCTD9,E2F7,CYR61,CALD1,FRAS1,MITF,DVL2,SP5,THRB,EPB41L5,PHF20L1,SMARCA2,NR3C1,FAM133B,ERBB2IP,DCP2,DPYSL3,ANKRD10,PLCG1,TIMP3,UEVLD,HNRNPH2,TMEM30A,RAP2C,NR4A3,PCDH19,SFMBT1,NFKBIZ,HOXB13,CEP41,CPEB2,RARG,TLL2 |
| 2.804e-04 | -8.18 | regulation of cellular localization | biological process | GO:0060341 | 1211 | 160 | 16441 | 1675 |
LAMP1,EXPH5,ILDR1,TXN,LGR4,CACNA2D2,IL18,ITPR2,SYTL4,CCNB1,SDC1,BARD1,ERP29,SLC8B1,NCS1,CALM2,RAB15,CABP1,SIVA1,DPYSL2,PASK,KCNS3,DLG1,ABCA2,TRPC1,MYRIP,RASGRP1,TRIM8,ACVR1C,NBPF3,EZR,PRKAR2B,SLC25A5,CDK1,ABR,TRIM9,PLCG1,KCNMB4,SLC25A4,DNM1L,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,BMF,NFKBIE,BVES,HLA-E,UBASH3B,RAB23,CALM3,FBLN1,IL18R1,ANO1,LMNA,ITGA3,RIMS3,KCNN4,NEK2,SORL1,MDFIC,CACNA1D,WNT3A,SYTL3,RIMS2,MDFI,CALM1,TP53INP2,STX3,CDK5R1,GNAS,TMEM30A,CDCA5,NFKBIA,ITPR1,YOD1,TMEM173,EHD1,LZTFL1,SORBS1,NF2,THRA,IQGAP1,TP53,ERBB2,CD274,BCL2L1,PRKACA,APC2,BCAP31,ARHGEF16,SYTL2,IER3,NOV,CDH1,SP100,DACT1,REEP1,CDH3,DAB2IP,TWIST1,PDE4D,RAB27B,MYT1,F2R,CHP1,SIRT1,ERLEC1,AKT1,PTGER4,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PPP2R5A,INPP4B,NRG1,EFNA5,SYT13,TCAF1,NKX3-1,PINK1,SDC4,PSMD10,TGFBR1,HMGN3,NEO1,KIF5B,CARD8,ADRBK1,ADORA1,PTEN,CDK16,LLGL2,BMP7,FAM20B,UBE2J1,BAX,TMBIM6,MAPK11,SYK,HES1,RHOA,RAB3B,SYBU,PIK3R1,LITAF,RGCC,GPLD1,NUCB1,BANK1,SYT7,ARRB1,SPCS3,GPER1,FZD5,PKIA |
| 2.805e-04 | -8.18 | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | MSigDB lists | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | 11 | 6 | 17758 | 1761 |
IRF7,IFIT1,DUSP4,USP18,RET,SERINC2 |
| 2.830e-04 | -8.17 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 32 | 17758 | 1761 |
BIN1,MAN2B2,CCDC109B,ARHGEF11,TSC22D3,UBASH3B,EPHA4,SNN,H1FX,IRF2BPL,FAM111A,PDE4D,CITED2,MYLIP,C9orf72,KIFC2,ITCH,RAPGEF2,UTRN,DIAPH2,TP53INP2,SOCS3,IRS2,PELI2,PRDM5,CCDC69,KLF11,MAFF,TOB1,CPEB2,PCSK5,KLF7 |
| 2.840e-04 | -8.17 | negative regulation of locomotion | biological process | GO:0040013 | 253 | 44 | 16441 | 1675 |
SEMA6B,TCAF1,ARAP3,NF2,ADGRG1,PKP2,VASH1,FBLN1,GRM5,NOV,SVBP,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,SEMA3G,CITED2,WNT3A,CYP1B1,SEMA3B,TRIM8,IFITM3,PTPRU,ACVR1C,PTGER4,RGCC,ARHGDIB,EPHA1,DAG1,ABR,DPYSL3,AP1AR,PTPRJ,ACVRL1,SEMA4D,CORO1C,SPINT2,RAP2C,NRG1,EGFL7,ITGAV,SEMA3A |
| 2.865e-04 | -8.16 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | 192 | 35 | 17758 | 1761 |
SCN5A,TTC39B,ARMC7,ARFGEF1,VASH1,PJA2,CYP26A1,APPBP2,HDAC9,M6PR,CA2,CTSC,RGS3,RAB20,MTMR11,ALPK1,PIKFYVE,RASGRP1,CTH,GFPT1,SSH3,ORAI2,BCL9,EZR,NFIX,TAPBP,SWAP70,RBL1,FAM114A1,ITPR1,SIPA1L1,SH3BP4,SLC4A3,ZDBF2,SLC25A38 |
| 2.865e-04 | -8.16 | GSE17721_0.5H_VS_4H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_POLYIC_BMDM_DN | 192 | 35 | 17758 | 1761 |
CCNI,LZTFL1,CUL4B,PDCL,TNFSF9,DOPEY2,RPS6KA2,EFR3A,IL6ST,MITF,IRF2,IGFBP2,OSTF1,TECR,TIAM1,MYT1,C9orf72,GFPT1,MOSPD2,NR3C1,NUB1,PARP4,PDK3,SPTLC2,PSMA4,ABR,ENDOD1,CARHSP1,PPP2R5A,CSF1,KBTBD2,PLK2,NFKBIA,GLCCI1,HIPK3 |
| 2.865e-04 | -8.16 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | 192 | 35 | 17758 | 1761 |
DDX58,CCDC109B,PARP12,IL15RA,IL15,PSME2,HLA-E,HLA-F,TAP1,HERC6,PRRG4,CDS1,RCN1,TYMP,FUT1,RAB20,PIM1,ETV7,APOBEC3G,MX1,ARAP2,PLSCR1,LITAF,UBE2A,RNF19B,CASP4,PSMA4,BCAR3,SECTM1,NMI,NOD2,IRF7,IFIH1,ISOC1,APOL2 |
| 2.865e-04 | -8.16 | GSE14308_TH2_VS_TH1_UP | MSigDB lists | GSE14308_TH2_VS_TH1_UP | 192 | 35 | 17758 | 1761 |
CD99,GCLM,SPRED1,TXN,SOX9,ETV5,PBX3,HMGN3,CENPN,IL6ST,PAPSS1,FAM63A,VAT1,CRTAP,RBMS2,ATP2B1,HES1,CAMSAP3,EIF5A2,CDC20,PRKRA,ANLN,TP53INP2,BCAR3,FUCA1,HS6ST1,CARHSP1,HNRNPH2,TMEM30A,RYK,GRIN2D,MLKL,ARPC2,HOOK1,TMEM131 |
| 2.894e-04 | -8.15 | regulation of protein transport | biological process | GO:0051223 | 725 | 103 | 16441 | 1675 |
EXPH5,TXN,LGR4,THRA,IQGAP1,CACNA2D2,ERBB2,IL18,ITPR2,SYTL4,CD274,PRKACA,BARD1,APC2,SLC8B1,ERP29,BCAP31,NOV,CDH1,SP100,DACT1,CABP1,KCNS3,DAB2IP,TWIST1,MYRIP,F2R,MYT1,RASGRP1,CHP1,SIRT1,ERLEC1,ACVR1C,PTGER4,NBPF3,EZR,PRKAR2B,PRKCQ,CD40,ITPR3,SLC25A5,SNX12,FZD7,IRS2,SLC25A4,DNM1L,RAB11FIP1,NOD2,EFNA5,NRG1,F2RL1,DDX58,TCAF1,PINK1,NFKBIE,HLA-E,RAB23,PSMD10,TGFBR1,HMGN3,FBLN1,IL18R1,ANO1,WWP2,NEO1,CARD8,LLGL2,CDK16,BMP7,KCNN4,FAM20B,UBE2J1,SORL1,TMBIM6,MAPK11,MDFIC,CACNA1D,WNT3A,SYK,MDFI,HES1,RHOA,PIK3R1,SYBU,LITAF,RGCC,CDK5R1,GPLD1,GNAS,NUCB1,BANK1,SYT7,TMEM30A,ITPR1,NFKBIA,ARRB1,YOD1,GPER1,SPCS3,FZD5,NDFIP1,TMEM173,PKIA |
| 2.921e-04 | -8.14 | regulation of cell-substrate adhesion | biological process | GO:0010810 | 166 | 32 | 16441 | 1675 |
NF2,SDC4,FBLN1,FAM21C,EMP2,ITGA3,CYR61,NPNT,PTEN,TBCD,BCL6,ADAM15,TACSTD2,EPB41L5,MFI2,FZD4,FMN1,PIK3R1,UTRN,EPHA1,FZD7,RASA1,AP1AR,ONECUT1,PTPRJ,ACVRL1,CSF1,CORO1C,TRIOBP,EFNA5,ARPC2,COL16A1 |
| 2.922e-04 | -8.14 | WEIGEL_OXIDATIVE_STRESS_RESPONSE | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_RESPONSE | 34 | 11 | 17758 | 1761 |
GNAS,ADORA1,NF2,DAPK1,BAX,CDH3,IGFBP2,HMGA1,FOS,NFIX,IER3 |
| 2.922e-04 | -8.14 | AIGNER_ZEB1_TARGETS | MSigDB lists | AIGNER_ZEB1_TARGETS | 34 | 11 | 17758 | 1761 |
EPCAM,CDH1,CRB3,TSPAN15,SHROOM3,CDH3,F11R,TACSTD2,MAL2,TSPAN1,OCLN |
| 2.922e-04 | -8.14 | SCHRAETS_MLL_TARGETS_UP | MSigDB lists | SCHRAETS_MLL_TARGETS_UP | 34 | 11 | 17758 | 1761 |
BTG3,SERPINE2,CTSC,CTSZ,FHL1,FOS,TSPAN7,TOB1,GM2A,FZD6,FAS |
| 2.924e-04 | -8.14 | chrxq23 | MSigDB lists | chrxq23 | 15 | 7 | 17758 | 1761 |
CAPN6,KLHL13,BHLHB9,ALG13,CUL4B,ZBTB33,RGAG1 |
| 2.924e-04 | -8.14 | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR | 15 | 7 | 17758 | 1761 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.935e-04 | -8.13 | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 222 | 39 | 17758 | 1761 |
FRMD4A,CPEB4,IQGAP1,UBASH3B,ITGA6,EPHA4,SLC7A2,BCL2L1,PHLDA1,CA2,IL6ST,TNFRSF12A,PDE4D,LMAN1,ULBP2,SYTL3,PPIF,DOCK4,PCGF5,RAB3B,ELK3,CD55,MFI2,PLAUR,PPARA,DNAJB14,LDB2,PGF,SERPINA1,UEVLD,OTUB2,NFKBIZ,HMGA1,GEM,ITPKA,ST3GAL1,MAFF,ESYT2,RRAGD |
| 2.950e-04 | -8.13 | microtubule | cellular component | GO:0005874 | 391 | 61 | 17570 | 1756 |
GAS2L1,DYNLRB1,CKAP2,IQGAP1,CALM3,KIF23,HDAC6,DNAH3,APC2,APPBP2,KIF5B,CALM2,SS18,STIM1,KIF14,DPYSL2,KIF13B,TBCD,NEK2,DLG1,KLC3,TUBG1,CLIP2,SPRY2,MYO5A,TPGS2,C9orf9,PLK1,CAMSAP3,KIFC2,KIF20A,CAPN6,SNTB2,STAU2,ASPM,CALM1,SYBU,PARP4,KIF1C,KIF13A,NUSAP1,KIF11,CDK1,GABARAPL1,NIN,CEP162,MID1IP1,DNM1L,SHROOM3,MAP2,FAM110C,AURKA,CENPE,NDE1,RGS14,CFAP20,SHROOM2,REEP4,HOOK1,RUSC1,SNPH |
| 2.954e-04 | -8.13 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 928 | 127 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,SSH1,NQO1,IL15,PSME2,RET,NRG2,ERBB2,PSME1,IL18,ITPR2,BCL2L1,CCNB1,HDAC6,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,RPS6KA2,CDH1,SHC3,KLF3,PIK3CA,AKR1B1,DAB2IP,GOT1,PDE4D,RASGEF1A,RASGRP1,FRS3,CYP1B1,PPIF,SIRT1,RIPK2,AKT1,FZD4,CASP9,EZR,PRKAR2B,CD40,POR,CASP4,RHEB,FZD7,SOCS3,IRS2,ENPP1,IDE,JAK1,CDK19,PTK7,AXL,NOD2,CAB39,EIF4EBP2,SPTBN5,NRG1,ABCA1,GAB1,RRAGD,PRKAA2,CPEB4,RASA2,SOX9,CALM3,PSMD10,ETS1,GSTP1,FGF19,HDAC9,TFAP4,CXCL16,IGF1R,CST3,COL6A1,KLF9,PIM1,ERBB3,NCAM1,WNT3A,MYO5A,PDGFC,RASGRF1,SHMT1,PSMB4,RAPGEF2,NR4A1,OXR1,CALM1,PIK3R1,GRIN1,LITAF,STRADB,YES1,PDK3,ELK1,FOS,BCAR1,PSMA4,RASA1,GPLD1,GNAS,FECH,NCOA3,PRKAG2,FGFR2,RAB11FIP2,NFKBIA,SH3BP4,NR4A3,OSER1,GRIN2D,NR4A2,GPER1,CMPK2,OSR1,MAP3K5,JAK3,TBC1D4,CPEB2,COL16A1,RARG |
| 2.962e-04 | -8.12 | INGRAM_SHH_TARGETS_UP | MSigDB lists | INGRAM_SHH_TARGETS_UP | 121 | 25 | 17758 | 1761 |
HES1,PLSCR1,NR3C1,NR4A1,TSC22D3,ASAH1,ITPR3,OAT,DOCK5,SEPP1,ABCD4,RASSF8,MFAP3L,ENPP1,SLC6A6,ADD3,IGF1R,CTGF,SNX18,PTK7,UBE2J1,KLF9,CMPK2,SLC27A3,CYP1B1 |
| 2.967e-04 | -8.12 | cellular protein localization | biological process | GO:0034613 | 1143 | 152 | 16441 | 1675 |
SUN1,LAMP1,EXPH5,UGT8,TAP1,F11R,MPP5,SYTL4,HDAC6,ERP29,ZFYVE16,RAB15,AP1M2,DLG1,SNX16,SUN3,RAB20,CTTN,TLN2,PACSIN1,TRAM1,MYRIP,PLK1,KCNIP3,CENPA,EZR,ARFRP1,KIF13A,ICMT,CDK1,ARF4,OPTN,DNM1L,WIPI1,GNPTAB,ARF6,RRAGD,NFKBIE,GGA1,PEX6,SOX9,ETV5,RAB23,RAB6A,CNTNAP2,LMNA,ATG4A,MESDC2,SNX18,RPL39,KIF13B,EXOC8,SORL1,PIKFYVE,WNT3A,SYTL3,NUP85,RIMS2,MDFI,KDELR1,TRAK2,PMPCB,STRADB,NUBP1,STX3,AP1AR,SCARB2,TIMM8A,TMEM30A,NFKBIA,SH3BP4,FAM83D,ZDHHC7,AURKA,CTSA,LTBP2,ATP1B3,JAK3,TOB1,EHD1,ARMCX3,THRA,TP53,PKP2,EMP2,STIL,BCAP31,SYTL2,APPBP2,ZFYVE9,TTC21B,ACAP2,CDH1,ZDHHC12,REEP1,ZDHHC23,BCL6,RPN2,IFIT1,RAB27B,DLG3,LMAN1,SNX10,F2R,DVL2,CHP1,ATG4D,SEC23A,SEC61B,AKT1,PTPRU,SYNE2,RAB38,PYGO1,ATP1B1,DAG1,ATP10D,DDOST,PEX2,PACSIN2,PINK1,CD63,TSPAN15,FRMD6,LRP4,PSMD10,PDIA3,AIP,VPS26A,SIX4,ZDHHC21,RNF128,MLPH,ADORA1,BMP7,BAX,PLEKHF1,SYK,MYO5A,HES1,SUN2,RAB3B,FBLN5,CRB3,RAPGEF2,PIK3R1,PRICKLE1,BBS2,CNTNAP1,RPL12,SPCS3,WDR45B |
| 2.968e-04 | -8.12 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | 185 | 34 | 17758 | 1761 |
CCNI,GALNT12,TSC22D3,MTL5,CA8,KBTBD11,DENND2D,SIRPA,ATG4A,CARD8,FRY,CTGF,MITF,BCL6,SGK1,FAM102A,PDE4D,TIAM1,MAST4,SPRY2,CTDSP2,FBLN5,CENPA,ELK3,ING1,LPGAT1,PIP4K2C,POR,RHEB,GABARAPL1,PLCH1,RHOBTB2,CABIN1,EGLN1 |
| 2.968e-04 | -8.12 | KRAS.DF.V1_UP | MSigDB lists | KRAS.DF.V1_UP | 185 | 34 | 17758 | 1761 |
ARHGEF3,DLGAP5,ATP9A,GNE,HERC5,BCL2L1,LTBP3,LGALS3BP,DPYSL2,FLRT3,FUT8,ALDH1A3,BCL6,TRPC1,ALDH7A1,IFIT1,FAR2,SPRY2,OPLAH,LOC81691,FADS2,DDB2,ELK3,CDA,LOXL2,BORA,MAP3K6,STEAP1,TP53I3,NAT1,INPP4B,PLIN3,SERPINB1,E2F8 |
| 2.968e-04 | -8.12 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | 185 | 34 | 17758 | 1761 |
SIGIRR,HECA,CCDC109B,UGP2,GALNT12,ITGA6,ARL4C,CYB561,DHRS3,RAB15,MGAT4A,IL6ST,FAM102A,WWP1,PIM1,TIAM1,MAST4,CPD,FBLN5,STAT4,PIK3R1,TCF7,PRKCQ,OPTN,PLCG1,ATP1A1,NGFRAP1,SEMA4D,LRIG1,INPP4B,FHL1,TBC1D4,PCSK5,DOCK9 |
| 2.976e-04 | -8.12 | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | 370 | 58 | 17758 | 1761 |
GRN,GAA,PCOLCE,ENO2,HLA-F,TSC22D3,CALB2,MGST2,CRABP2,SDC1,MERTK,DDR1,HOXB2,EFNB1,SPTB,ARHGEF16,SIRPA,ITGA3,RPL39,CST3,MITF,FOSB,CD9,DAPK1,SORL1,ALDH7A1,LGMN,NCAM1,PLCB2,TIAM1,MYO5A,RBMS2,MX1,SYPL1,HES1,TGIF1,PCDH1,ALDH2,NR4A1,PRKAR2B,YES1,CD40,FOS,GNA11,GPLD1,MDK,FUCA1,MAPKAPK2,CNTNAP1,TIMP3,SERPINA1,CSF1,NFKBIA,SPINT2,SERPINB6,HOXB13,LTBP2,HSPB1 |
| 2.979e-04 | -8.12 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | 24 | 9 | 17758 | 1761 |
DDB2,CSF1,DRAM1,PDK3,SESN1,NUP62CL,DENND2D,LEPR,FAS |
| 2.980e-04 | -8.12 | FERM_CS | interpro domains | IPR019747 | 24 | 9 | 18293 | 1814 |
EPB41L5,FRMD4A,NF2,EZR,EPB41L4B,TLN2,EPB41L4A,FRMD4B,FARP2 |
| 2.992e-04 | -8.11 | MICROTUBULE_CYTOSKELETON | MSigDB lists | MICROTUBULE_CYTOSKELETON | 149 | 29 | 17758 | 1761 |
PLK1,PCGF5,DLGAP5,CDC20,KIF23,HDAC6,KIF11,CDK1,RANBP9,APPBP2,SAC3D1,NIN,ATG4A,TOP2A,KIF5B,CNTRL,MAP2,TBCD,ABCA2,NEK2,TUBG1,AURKA,BUB1,CEP41,NDE1,CLIP2,CCNB2,ESPL1,ATG4D |
| 3.000e-04 | -8.11 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 45 | 13 | 17758 | 1761 |
BIN1,TIMP3,ITGA3,SOX9,SH3BP4,BMP1,TNFRSF12A,CD70,BCL2L1,F2RL1,CARD10,GCNT1,SEMA3B |
| 3.014e-04 | -8.11 | Signalling to ERKs | REACTOME pathways | R-HSA-187687 | 246 | 44 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,MAPKAPK2,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,MAPK12 |
| 3.026e-04 | -8.10 | reproductive structure development | biological process | GO:0048608 | 400 | 63 | 16441 | 1675 |
COL9A3,NKX3-1,GRHL2,SERPINE2,CDKN1C,LGR4,EPAS1,ST14,CENPI,SOX9,TGFBR1,BCL2L1,SDC1,MERTK,PDGFB,SIX4,SGPL1,CCND1,E2F7,DAZAP1,IGF1R,ITGB8,LRRC6,PTEN,CYR61,GATA2,CST3,TOX2,DLG1,BAX,PLK4,TIPARP,MDFI,REC8,SIRT1,HES1,AKT1,FZD4,ASPM,TFAP2C,CCNF,FNDC3A,IDH1,PRDX4,SOCS3,PITX2,HS6ST1,NCOA3,FGFR2,HOXA9,AXL,CTSV,SPINT2,ARRB1,HOXB13,FZD5,OSR1,SOX8,E2F8,GAB1,AHR,RARG,EGLN1 |
| 3.031e-04 | -8.10 | Ser/Thr_dual-sp_kinase | interpro domains | IPR002290 | 268 | 45 | 18293 | 1814 |
PRKAA2,CDK17,NUAK1,CIT,CAMKK1,RPS6KA1,CAMK1D,GRK6,PKN1,PRKACA,DAPK2,RPS6KA2,ADRBK1,CDK16,PASK,SGK3,DAPK1,PRKG1,PLK4,NEK2,SGK1,MAPK11,PIM1,MAST4,MAP3K3,PLK1,AKT1,PRKCQ,MAP3K6,ADRBK2,STK17B,CDK1,STK17A,MAPKAPK2,STK26,CDK19,STK38,PLK2,AURKA,STK39,CDK18,MAP3K5,HIPK3,MELK,MAPK12 |
| 3.041e-04 | -8.10 | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | MSigDB lists | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | 75 | 18 | 17758 | 1761 |
SMARCA2,PHLPP1,RASA1,MECOM,MDK,HLF,TIMP3,PLOD2,LRIG1,INPP4B,PPM1H,FAM117A,ZNF165,SERPINI1,KLF9,F2RL1,HSPB1,CCDC88A |
| 3.056e-04 | -8.09 | ephrin receptor signaling pathway | biological process | GO:0048013 | 92 | 21 | 16441 | 1675 |
MYL9,RHOA,ARHGEF28,EPHA4,GRIN1,EPHA1,YES1,EFNB1,MYL12A,RASA1,CDK5R1,EPHA10,SS18,LIMK1,SIPA1L1,EFNA5,MYH14,EPHB4,ARPC2,TIAM1,MYL12B |
| 3.059e-04 | -8.09 | hematopoietic or lymphoid organ development | biological process | GO:0048534 | 569 | 84 | 16441 | 1675 |
CASP3,ADD1,HOXB7,EPAS1,IL15,THRA,RET,TP53,CACNB4,PDGFB,TNFSF9,SPTB,ARTN,LMO4,PLCG2,MITF,IL31RA,TMEM143,BCL6,RTKN2,PIK3CD,SNX10,TIPARP,OSTM1,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,HOXA9,AXL,PTBP3,DHTKD1,F2RL1,RUNX2,TNRC6C,CDKN1C,BVES,TGFBR1,PKN1,HERC6,MERTK,IL18R1,SIX4,HDAC9,MECOM,SGPL1,TOP2A,CD109,GATA2,BAX,CITED2,WNT3A,SYK,FARP2,HES1,RHOA,RC3H2,PIK3R1,TTC7A,RUNX3,EIF2AK1,FOXL1,FAS,PITX2,FECH,ONECUT1,FGFR2,TWSG1,DHRS2,CSF1,PPP2R3C,LRRK1,FZD5,CCNB2,SLC25A38,JAK3,MELK,JARID2 |
| 3.062e-04 | -8.09 | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | MSigDB lists | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | 29 | 10 | 17758 | 1761 |
TGIF1,NFKBIA,KLF3,KIF23,SGK1,TCF7,PIM1,TOB1,RASGRP2,CKS2 |
| 3.065e-04 | -8.09 | SENESE_HDAC1_TARGETS_DN | MSigDB lists | SENESE_HDAC1_TARGETS_DN | 230 | 40 | 17758 | 1761 |
NUDT6,FOXO6,BCAM,MRC2,TRIM2,RUNX2,ALDH6A1,ZNF395,AASS,DNAJB2,FLYWCH2,SDC1,FBLN1,ARHGEF40,EPS8L2,NOTCH3,MYBL1,F2R,EPB41L5,THRB,ORAI2,SSH3,CYS1,UTRN,STMN3,TNS1,BCAR1,FOS,COL12A1,ARHGAP35,ALDH5A1,DHRS2,ITGA7,FAM114A1,HDAC1,IFI6,NRBP1,L1CAM,COL16A1,KLF7 |
| 3.066e-04 | -8.09 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 178 | 33 | 17758 | 1761 |
MAN2B2,ATP8A1,UBASH3B,ITGA6,EPHA4,ASAH1,SNN,HERC6,DTX3L,MARCH8,SESN3,TRANK1,IQCE,SGK1,MARCH2,PIM1,RAPGEF2,COQ10B,RGAG1,CASP4,CDK5R1,SOCS3,CD83,IRS2,COQ10A,NR1D2,PELI2,NFKBIZ,NR4A2,EPB41L4A,TOB1,MAFF,PCSK5 |
| 3.085e-04 | -8.08 | Signalling to RAS | REACTOME pathways | R-HSA-167044 | 239 | 43 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,MAPKAPK2,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,MAPK12 |
| 3.085e-04 | -8.08 | epithelial tube formation | biological process | GO:0072175 | 125 | 26 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SOX9,SDC4,RET,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,SOX8,OSR1,COBL,RARG,DVL2 |
| 3.093e-04 | -8.08 | Fosphenytoin (Antiarrhythmic) Metabolism Pathway | SMPDB pathways | SMP00618 | 4 | 4 | 978 | 131 |
SNTA1,SCN5A,SNTB1,SNTB2 |
| 3.100e-04 | -8.08 | head development | biological process | GO:0060322 | 693 | 99 | 16441 | 1675 |
EMX1,CASP3,NF2,HSPG2,GRHL2,AK7,THRA,CAST,TP53,NDRG2,OSR2,STIL,PHLDA1,TTC21B,CALM2,APLP2,CDH1,DPYSL2,KIF14,ALDH1A3,LHX6,SRR,DAB2IP,DIXDC1,NOTCH3,ZBTB18,TIPARP,BTBD3,SPEF2,MBP,CELSR2,FZD4,TFAP2C,ZFAND5,ARF4,ABR,ARHGAP35,NFIX,EDNRA,IRS2,MDK,AXL,TRABD2A,NRG1,NRGN,SCN5A,ANXA3,CDH22,SERPINE2,ADGRG1,CALM3,CNTNAP2,SEPP1,ETS1,HOXB2,FZD6,SGPL1,MECOM,FOXP2,IGF1R,GATA2,PTEN,FLRT3,CST3,CD9,PRKG1,BAX,WNT3A,HES1,RHOA,TACC1,RAPGEF2,ASPM,CALM1,GRIN1,AK4,TCF7,SCRIB,BBS2,NFIB,CRISPLD2,CDK5R1,FAS,PITX2,CDK5RAP1,FAT4,TWSG1,FGFR2,PHLPP2,DBI,NR4A3,RYK,PCDH19,NR4A2,NDE1,WDR62,SHROOM2,SEMA3A,RARG |
| 3.105e-04 | -8.08 | regulation of growth | biological process | GO:0040008 | 635 | 92 | 16441 | 1675 |
GAS2L1,ACACB,NF2,FOXM1,RPS6KA1,CACNA2D2,TP53,ERBB2,MORF4L2,PLXNA1,CCNB1,CDKN2C,NOV,CTGF,KIF14,DPYSL2,BCL6,PIK3CA,CDKN1B,DAB2IP,SEMA3G,CTTN,ACSL4,LGMN,CDKN2D,SEMA3B,SIRT1,SMARCA2,ING1,AKT1,ITCH,SERTAD3,CDA,EZR,PRKCQ,SAV1,POR,SOCS3,JADE1,ENPP1,PTPRJ,WFS1,LIMK1,NKD1,NOD2,ADIPOR1,EFNA5,NRG1,SEMA6B,IGFBP6,SERPINE2,ARHGEF11,PSMD10,TGFBR1,CRABP2,SPR,SIX4,PPP2R3A,SGPL1,IL17RB,CXCL16,CYR61,PTEN,MEGF8,SGK3,SGK1,ADAM15,IGFBP2,MAPK11,TNFRSF12A,WNT3A,OSGIN1,RIMS2,SOCS5,RHOA,FBLN5,MFI2,BBS2,BCAR1,CDK5R1,RASGRP2,GNAS,FGFR2,SEMA4D,ACVRL1,CSF1,CGREF1,SH3BP4,FHL1,HOXB13,SEMA3A,L1CAM |
| 3.151e-04 | -8.06 | IGARASHI_ATF4_TARGETS_DN | MSigDB lists | IGARASHI_ATF4_TARGETS_DN | 88 | 20 | 17758 | 1761 |
PACSIN2,OSTM1,NCKAP1,NEURL1B,LEPR,FZD6,CDS1,NOV,CDK19,PVRL2,GNPTAB,KCNS3,OPN3,POF1B,PGM2L1,ARRB1,SORL1,RAP1GAP,PRR15,DENND5B |
| 3.157e-04 | -8.06 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 171 | 32 | 17758 | 1761 |
TXN,IL15RA,SDC4,IL18,CD274,TNFSF9,IER3,OTUD1,E2F7,PIK3AP1,FJX1,UBE2J1,DRAM1,SELK,ATP2B1,LAMP3,B3GNT2,RIPK2,PLAUR,STAT4,RAPGEF2,SAV1,CDK1,SOCS3,CD83,ETS2,MFSD2A,NFKBIA,NFKBIZ,PLD1,GEM,MAFF |
| 3.172e-04 | -8.06 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_DN | 193 | 35 | 17758 | 1761 |
TBC1D1,FRMD6,RUSC2,OSGIN2,NDRG2,F11R,BCL2L1,RAD23A,ATP6V0B,RPS6KA2,ADRBK1,ARTN,PIK3AP1,MITF,CTTN,SGCB,MGAT5,TESK1,SYNE2,DIAPH2,IGSF8,MAP3K6,ABR,ARF4,CD83,MAPKAPK2,PLCG1,PTPRJ,PPP2R5A,RND3,NFKBIA,HDAC1,TRAF5,JARID2,PCSK5 |
| 3.172e-04 | -8.06 | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | 193 | 35 | 17758 | 1761 |
HECA,PPP1R2,TCTN2,EPHA4,PDIA3,GRK6,NUP62CL,IL17RB,DAZAP1,ACAP2,MDFIC,TAGLN2,CITED2,TRAM1,RASGRP1,CRTAP,ELK3,SLC39A8,MBNL3,SESN1,ALCAM,FRMD4B,RBL1,LRIG1,INPP4B,PGRMC1,AGFG2,CAB39,CLMN,FAM117A,EIF4EBP2,ARF6,REEP4,AHR,DOCK9 |
| 3.172e-04 | -8.06 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | 193 | 35 | 17758 | 1761 |
EPAS1,PTTG1,C5orf30,KCTD12,DHRS3,CYP39A1,ACAP2,GNB5,ARSG,KLF3,RFX5,IFIT1,C10orf54,CITED2,TMTC1,KCNIP3,OXR1,UTRN,PDE5A,EPHA1,FOS,ATP10D,ALDH3B1,KLF12,ABCB1,IRF7,SERPINI1,IFIH1,TMEM14A,TOB1,ABCA1,CPEB2,ESYT2,ABCG1,XDH |
| 3.172e-04 | -8.06 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | 193 | 35 | 17758 | 1761 |
PLA2G4A,PPP1R2,SDC4,TP53,KIF23,NDUFA4,PDIA4,TOP2A,KIF14,BDH1,FUT8,DAPK1,ALDH3A2,CKS2,PPIF,NFE2L3,PLK1,CENPA,MRPS33,GGH,PCTP,BORA,CDK1,PRIM1,FRMD4B,BCAR3,DCTN6,H1F0,DBI,PRPS2,RAB11FIP1,CAB39,ADIPOR1,NCAPG2,ACOT7 |
| 3.191e-04 | -8.05 | ATPase activity, coupled to movement of substances | molecular function | GO:0043492 | 119 | 25 | 16491 | 1673 |
ATP9A,ATP8A1,RALBP1,ATP2C2,TAP1,ABCG2,ATP1B1,ATP8B3,ATP10D,ABCD4,ATP13A2,ATP6V0B,TAPBP,ATP1A1,ATP7B,PCYOX1,ABCA2,ABCB1,ATP8B1,ABCD1,ATP1B3,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 3.197e-04 | -8.05 | negative regulation of cellular component movement | biological process | GO:0051271 | 232 | 41 | 16441 | 1675 |
SEMA6B,TCAF1,ARAP3,NF2,ADGRG1,PKP2,VASH1,FBLN1,NOV,SVBP,ADORA1,SP100,PTEN,ADAM15,CDKN1B,DAB2IP,TACSTD2,SEMA3G,CITED2,WNT3A,CYP1B1,SEMA3B,PTPRU,ACVR1C,PTGER4,RGCC,ARHGDIB,EPHA1,DAG1,ABR,DPYSL3,AP1AR,PTPRJ,ACVRL1,SEMA4D,CORO1C,SPINT2,RAP2C,NRG1,EGFL7,SEMA3A |
| 3.199e-04 | -8.05 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | 51 | 14 | 17758 | 1761 |
PDGFA,TIMP3,IGF1R,IGFBP6,CDH1,BMP7,RET,ERBB2,RUNX3,ITGAV,SEPP1,SDC1,ALCAM,RARG |
| 3.217e-04 | -8.04 | REACTOME_SIGNALING_BY_FGFR | MSigDB lists | REACTOME_SIGNALING_BY_FGFR | 108 | 23 | 17758 | 1761 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,FGFR2,PIK3CA,CDKN1B,SPRY2,GAB1,FRS3 |
| 3.266e-04 | -8.03 | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | MSigDB lists | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | 300 | 49 | 17758 | 1761 |
CCNE2,UGP2,CDKN1C,CPEB4,C5orf30,RAB23,SNN,DNAJB9,WWP2,KIF5B,SESN3,FRY,GRHL1,PIK3AP1,GATA2,CDK16,RGS3,XYLT2,FAM13B,CNNM4,DUSP10,DAB2IP,PIKFYVE,MYLIP,SCN3A,TRAK2,SOCS5,TGIF1,PLEKHA6,PTGER4,SERTAD3,LHFPL2,NFIB,BSDC1,COL12A1,NFIX,RBM47,PHLPP2,CDCA7L,ITPR1,NR4A3,PITPNA,STK39,ITGAV,GDF11,CEP41,CPEB2,TOB1,DOCK9 |
| 3.267e-04 | -8.03 | BRUINS_UVC_RESPONSE_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_LATE | 1078 | 141 | 17758 | 1761 |
MYL9,GNPDA1,TMEM41B,TEX2,NANS,ITPR2,DPP8,LTBP3,PLS3,UBE2T,ELMO2,OSBPL3,SLC44A1,TUBG1,RAB20,RP2,ACOX2,RCAN3,TLN2,TRAM1,NEB,DDX59,LOC81691,PCGF5,SGCE,CD55,TNIP1,CDA,LOXL2,ICMT,CDK1,POR,COL12A1,PRIM1,MFAP3L,ENPP1,NEIL1,GDE1,FAM114A1,CAB39,MRPS28,GLA,CAPN1,LRRFIP2,TBC1D1,RASA2,HERC6,ANO1,VASN,COL6A1,TBCD,TPST1,DAPK1,PIKFYVE,SLC12A2,FADS2,ELK3,KLK5,PRSS23,EPHA1,PSMA4,SCARB2,DCK,MFSD2A,MATN2,FAM83D,FGD6,DONSON,PLIN3,TOB1,MTM1,FAM92A1,IL15,CAST,PTTG1,PDIA5,FAM198B,AIFM2,EPS8L2,RAD23A,RCN1,APOBEC3B,DOK4,BCL6,DIXDC1,ACSL4,PDIA6,SEC61B,DRAP1,HTATIP2,CD40,MYL12A,TAPBP,NGFRAP1,MLKL,CMAS,CTHRC1,GCLM,PCOLCE,PACSIN2,KLHL13,DCAF7,EPS8,RASSF7,PSMD10,COL4A5,FBXO6,PARM1,C16orf74,PTEN,CDK16,UBE2J1,GTF2F2,TRIM21,TMBIM6,CITED2,ATP2B1,MYO5A,CRTAP,FAH,PGM1,FBLN5,PLSCR1,DIAPH2,TTC7A,CCDC34,BLVRA,CRISPLD2,CDK5RAP1,ENDOD1,SWAP70,ACADSB,TWSG1,NMI,ABCB1,CSTF2,ERAP1,GRIN2D,ARSB,AHR,ABCG1 |
| 3.276e-04 | -8.02 | RHO GTPases activate PAKs | REACTOME pathways | R-HSA-5627123 | 23 | 9 | 8202 | 867 |
MYL9,CALM2,NF2,LIMK1,CALM1,CALM3,MYH14,CTTN,MYL12B |
| 3.279e-04 | -8.02 | Ndc80 (NDC80 homolog, kinetochore complex component (S. cerevisiae)) | protein interactions | 67052 | 32 | 11 | 16036 | 1726 |
HMMR,RCN1,ZWINT,SPC25,ASPM,RRBP1,NDC80,NUF2,BUB1,IQGAP3,PHKA2 |
| 3.293e-04 | -8.02 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 186 | 34 | 17758 | 1761 |
LGALS3,CDKN1C,DNAJC3,NENF,MORF4L2,CRABP2,NUCB2,SDC1,EPS8L2,ARHGEF16,LMNA,DNAJB9,CHPF,BTG3,CST3,RRBP1,KDELR1,SEMA3B,PODXL2,RAPGEF2,C1GALT1C1,BLVRA,MCFD2,RHEB,SOCS3,FUCA1,MDK,RBM47,WIPI1,PRCP,MMP17,NFKBIA,ADIPOR1,MAPK12 |
| 3.293e-04 | -8.02 | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | 186 | 34 | 17758 | 1761 |
PLA2G4A,DDX58,LRRFIP2,TTC39B,IL15,HERC5,CD274,DTX3L,TRIM21,IRF2,IFIT1,KLF9,OAS3,ETV7,CKAP4,PARP9,USP18,COQ10B,MICB,NUB1,PTGER4,RUNX3,IFIT3,C19orf66,NFKBIA,NLRC5,NR4A3,NFKBIZ,IRF7,CMPK2,IFIH1,RARG,IFI6,MELK |
| 3.296e-04 | -8.02 | YOSHIMURA_MAPK8_TARGETS_UP | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_UP | 1274 | 163 | 17758 | 1761 |
RET,TAP1,FBXO2,IL18,PSME1,CCNB1,CACNB4,PDGFB,SH3KBP1,GRM5,CALM2,EPCAM,WEE1,BTG3,PSMD1,CYP1A1,SHC3,DLG1,FUT1,IRF2,TACSTD2,PIK3CD,ACOX2,PTPRE,MGAT5,ACVR1C,MTRF1L,EDNRA,GDE1,MAP2,DNM1L,KCNK1,LIMK1,ATP7B,MADD,ITPKA,HSPB1,NRGN,F2RL1,MYL12B,CDKN1C,HLA-E,TMEM55B,HLA-F,CALB2,CALM3,COX6C,HPCAL4,CA2,IGF1R,MAP3K9,EXOC8,PIM1,CACNA1D,C10orf54,CALM1,PIP4K2C,GNA11,CDK5R1,SOX13,PTPRF,GNAS,GABRD,SCARB2,FAAH,ITPR1,SLC4A3,EGFL7,CABIN1,STK39,TMEM120A,HOOK1,SEMA3A,SLC2A4,HOXB7,NF2,FOXM1,TRIP10,INPP5D,RALBP1,ERBB2,MRAS,SLC7A2,BCL2L1,DDR1,IER3,CDS1,CCND1,SCNN1A,PLCG2,FABP6,PDE4D,EPB41L4B,ACSL4,SCN3A,GPX4,MYO5B,PPIF,PTPRU,PTGER4,KIF1C,DNAJB14,DUSP4,ALCAM,SOCS3,IRS2,IDE,ATP1A1,BFSP1,NRG1,EFNA5,MAPK12,BIN1,NUDT6,CDH22,HAL,SELL,GABRG2,AES,GDF15,SPR,SEPP1,ETS1,EFNB1,LGALS3BP,SLC9A2,SIRPA,PTEN,CTSC,CDK16,BMP7,BAX,IGFBP2,ERBB3,CITED2,SYK,ATP2B1,DLGAP1,OPLAH,HES1,RAB3B,PSMB4,NR3C1,PLAUR,PPARA,GRIN1,FURIN,BCAR1,FOS,LEPR,SERPINA1,ACADSB,SYT7,NAT1,NR4A3,GRIN2D,HMGA1,WDR62,HIPK3,L1CAM,AHR,ACOT7,OCLN |
| 3.298e-04 | -8.02 | HOLLMANN_APOPTOSIS_VIA_CD40_DN | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_DN | 246 | 42 | 17758 | 1761 |
PARP12,HOXB7,S100A11,GNPDA1,HLA-E,HLA-F,TP53,PSME1,OSR2,MGST2,DENND2D,LGALS3BP,HDAC9,B3GALNT1,EFR3A,CTSC,BMP7,RRBP1,CD9,CDKN1B,HLA-C,ARMCX6,LRIF1,TRAM1,FADS2,PGM1,MBP,CYB5R2,LITAF,NPC2,SAV1,PCTP,CASP4,RASGRP2,ANKRD10,HLA-B,SPINT2,RYK,TLE1,SERPINB1,IFIH1,TMEM131 |
| 3.309e-04 | -8.01 | REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | REGULATION_OF_TRANSFERASE_ACTIVITY | 157 | 30 | 17758 | 1761 |
CCNE2,SPRED1,CDKN1C,ERBB2,HERC5,STRADB,PIF1,PKMYT1,PKN1,TRIB2,MAP3K6,CARD10,CDK5R1,CCND1,CDKN2C,DIRAS3,CDK5RAP1,PTEN,RBL1,RGS3,MADD,MAP3K9,SERINC2,MDFIC,MAP3K5,CDKN2D,HIPK3,CCDC88A,CKS2,MDFI |
| 3.309e-04 | -8.01 | endomembrane system organization | biological process | GO:0010256 | 441 | 68 | 16441 | 1675 |
SUN1,ARFGEF1,PKP2,F11R,MPP5,CCNB1,EMP2,SPTB,RAB15,CDH1,REEP1,DLG1,ZDHHC23,SUN3,LMAN1,ANO4,PACSIN1,F2R,SNX10,XKR8,PLK1,ATL1,CLCN3,KCNIP3,AKT1,COG2,SYNE2,EZR,KIF13A,ARFRP1,ATP1B1,RAB38,CDK1,OPTN,SPTBN5,REEP4,ABCA1,PACSIN2,SERPINE2,TSPAN15,ANO9,LMNA,DOPEY2,PTEN,A4GALT,EXOC8,PLEKHF1,ATP8B1,NUP85,ALS2CL,MYO5A,SUN2,RAB3B,PLSCR1,CRB3,RAPGEF2,ANO6,ATP8B3,BBS2,FAT4,SYT7,PVRL2,ATP1B3,GPER1,CCNB2,HOOK1,NUP58,GOLGB1 |
| 3.364e-04 | -8.00 | LU_AGING_BRAIN_DN | MSigDB lists | LU_AGING_BRAIN_DN | 150 | 29 | 17758 | 1761 |
RASGRF1,SMARCA2,CDH22,ATP8A1,CALB2,CALM1,C5orf30,C6orf106,CALM3,TGOLN2,RAB6A,RNF19B,RANBP9,PARM1,CDK5R1,RAD23A,CALM2,GABRD,B3GALNT1,ETS2,GNB5,MAP2,NR1D2,DNM1L,MEGF8,PITPNA,PDE4D,ITPKA,GAD1 |
| 3.372e-04 | -7.99 | negative regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043124 | 50 | 14 | 16441 | 1675 |
SIRT1,NOV,RHOA,CARD8,TNIP1,NLRX1,BMP7,NFKBIA,LITAF,PSMD10,TLE1,DAB2IP,GSTP1,OPTN |
| 3.381e-04 | -7.99 | ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 122 | 25 | 17758 | 1761 |
SEC61B,SLC25A13,ABCG2,SLC1A3,SLC7A2,ATP1B1,SLC20A1,SLC9A2,SLC9A7,ABCD4,TAPBP,SLC6A6,ATP1A1,SLC4A4,ATP7B,SLC9A6,SLC44A1,SLC4A3,SLC44A2,ATP8B1,ATP1B3,SLC12A2,ATP2B1,ABCG1,ABCC1 |
| 3.391e-04 | -7.99 | growth cone | cellular component | GO:0030426 | 128 | 26 | 17570 | 1756 |
ORAI2,RASGRF1,TIMP2,IQGAP1,CALM1,EPS8,EPHA4,CALM3,STMN3,NDRG2,STX3,CDK5R1,DPYSL3,CALM2,ITGA3,SNX18,FLRT3,DPYSL2,EXOC8,TMOD2,MYH14,CTTN,DLG3,COBL,L1CAM,MYO5A |
| 3.460e-04 | -7.97 | DORN_ADENOVIRUS_INFECTION_48HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_48HR_DN | 40 | 12 | 17758 | 1761 |
BCAR3,CCND1,CYR61,RND3,NR4A1,PLK2,NFKBIA,SGK1,TNFRSF12A,COL7A1,IER3,CD83 |
| 3.460e-04 | -7.97 | GNF2_RFC3 | MSigDB lists | GNF2_RFC3 | 40 | 12 | 17758 | 1761 |
HMMR,TOP2A,FOXM1,ASPM,RANBP1,NDC80,CENPE,UBE2C,KIF11,CDK1,FANCI,CKS2 |
| 3.460e-04 | -7.97 | ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | MSigDB lists | ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | 40 | 12 | 17758 | 1761 |
TAPBP,ATP1A1,RALBP1,ATP7B,ABCG2,ATP8B1,ATP1B3,ATP1B1,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 3.460e-04 | -7.97 | PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 40 | 12 | 17758 | 1761 |
TAPBP,ATP1A1,SEC61B,ATP7B,ABCG2,ATP8B1,ATP1B3,ATP1B1,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 3.463e-04 | -7.97 | brainstem | COSMIC cancer mutations | brainstem | 3233 | 373 | 17775 | 1757 |
AASS,AK7,ATP8A1,DNAJC3,RET,CACNA2D2,PPFIBP2,FBXO2,PLXNA1,LACTB2,VASH1,ZNF275,SLC9A7,CDKN2C,KIAA1107,STIM1,CYP2S1,AOX1,PIK3CA,TUBG1,ATRNL1,CRY2,MGAT5,ERAP2,TNIP1,SH3BGRL,CDA,SLC35C1,PRKAR2B,TNS1,LOXL2,GALNT7,LDB2,POR,AHRR,RBM47,ATP7B,TRAF3IP1,PRDM5,AGFG2,MRPS28,WBSCR27,GAB1,DDX58,SCN5A,MRC2,FRMD4A,SCOC,TBC1D1,ITGA6,SLC25A27,SLC1A3,GPSM2,TNFRSF19,TTYH3,KIAA1161,ELF3,DOPEY2,FRY,FAM189A1,AIM1,PRKG1,TPST1,SORL1,CADPS2,OSTF1,ALPK1,CACNA1D,NCAM1,MYLIP,ULBP2,C9orf72,MCCC2,IGSF3,GFPT1,DDB2,KLK5,SLC37A1,KIF20A,TBC1D8B,SALL4,MICB,AMER1,NPHP3,ANTXR1,PCTP,SFXN5,PSMA4,GNA11,NFIB,DCP2,CYB5A,MMP15,PTPRF,DGKH,CACHD1,SLCO4A1,GABRD,PELI2,DCK,ITPR1,CLMN,PCDH19,CABIN1,PLIN3,HOOK1,RUSC1,MTM1,RNF224,TCTN2,ST14,C5orf30,RGS20,PKP2,FTH1,REPS1,ZNF385B,APOBEC3B,MUC16,CDH1,LRP11,MYO5B,CAPN6,FOXJ2,SEPT6,SYNE2,UTRN,TMEM144,PRKCQ,XRCC6BP1,ITPR3,ASB13,ALCAM,CMTM7,JAK1,SHROOM3,CORO1C,SLC27A1,NRG1,PRIMA1,SLC27A3,NR3C2,COBL,ARHGEF3,EPS8,BTN3A1,PBX3,CYB561,NUCB2,DNAH3,WWP2,ITGB8,IGSF9,RNF128,ANKS1B,PTEN,CALD1,MGAT4A,FUT8,SGK3,PLEKHF1,TAGLN2,NCOA2,PARP9,FARP2,PVRL4,ADAMTS2,PDGFC,B3GNT2,LCA5,ARAP2,ERMAP,FAM160A1,RAPGEF2,PIK3R1,CXorf57,FURIN,MYEOV,DIAPH2,YES1,SNTB1,ACADSB,PLOD2,FGFR2,RAB11FIP2,ACVRL1,AMMECR1,ABCB1,CSTF2,ITGAV,WDR62,CYBRD1,MELK,TLL2,TMEM131,ESYT2,JARID2,LTBP1,UGT8,FAM199X,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,ITPR2,HDAC6,DNER,KREMEN1,TMC1,SPTB,SH3KBP1,PLS3,HTR1D,NKAIN3,HSF2,NPNT,DPYSL2,TSPAN6,PAPSS1,ELF5,ANKFN1,SLC44A1,DLG1,POF1B,NTN4,MYH14,ANO4,TECR,SLC39A10,MYRIP,NEB,LAMP3,ZNF462,THRB,MCTP1,ITCH,CR2,ROR1,PRKRA,IDH1,SESN1,PTGFRN,RHEB,EDNRA,HS6ST1,KCNMB4,KLF12,EPB41L4A,CAPN1,GRN,PARP12,UBASH3B,CNTNAP2,FAM81A,PHLPP1,FBLN1,DHRS3,AIM1L,TNS3,DAZAP1,CA2,IGF1R,FRAS1,AHCY,LIMCH1,GAD1,MPHOSPH9,ALS2CL,CKAP4,SNX7,ABCC1,CHSY3,PODXL2,PLEKHA6,CORO2A,ZNF320,HEATR5A,RASGRP2,GNAS,BCAR3,UAP1,CSF1,NLRC5,ALPK3,LTBP2,ZDBF2,SHROOM2,SEMA3A,COL16A1,RARG,SNX30,LMO7,NCKAP5,TMX4,TP53,PDIA5,COL18A1,IL27RA,PHLDA1,CYP26A1,KCTD9,TTC21B,EFR3A,WDR44,EPB41L4B,NOTCH3,OAS3,TMTC1,MBP,AKT1,C3orf52,ACO1,DOCK5,DNAJC10,PTPRJ,RBL1,ABHD12,PTK7,SECTM1,TLE1,EFNA5,LIFR,CMAS,GOLIM4,ARHGEF11,POC1B,GABRG2,SELL,HMGN3,POMGNT1,LBR,FZD6,NRP2,SLC9A2,PPP2R3A,TMEM63A,ZDHHC21,MDM1,MLPH,LLGL2,LYPD6,BMP7,KIAA0319,UBE2J1,KLF9,IQGAP3,MYO5A,HMMR,DLGAP1,RAB3B,CRB3,NR3C1,AMFR,ASPM,RC3H2,PPARA,LRRC66,OGDHL,TTC7A,MAML2,DGKE,KLHL2,ENDOD1,HLA-B,BANK1,SWAP70,TWSG1,OTUB2,ARRB1,ZMIZ1,PLOD3,TBC1D4 |
| 3.465e-04 | -7.97 | microtubule binding | molecular function | GO:0008017 | 197 | 36 | 16491 | 1673 |
GAS2L1,KIF23,HDAC6,APC2,KIF5B,STIM1,DPYSL2,KIF13B,KIF14,REEP1,KLC3,CLIP2,CCDC88A,CHP1,DPYSL5,PLK1,CAMSAP3,SUN2,KIFC2,KIF20A,CAPN6,FMN1,SYBU,EZR,KIF1C,KIF13A,NUSAP1,KIF11,GABARAPL1,MAP2,TRAF3IP1,FAM83D,CENPE,RGS14,NDE1,REEP4 |
| 3.500e-04 | -7.96 | BAND41 | prints domains | PR00935 | 25 | 9 | 4759 | 462 |
EPB41L5,FRMD4A,NF2,EZR,EPB41L4B,EPB41L4A,MYLIP,FRMD4B,FARP2 |
| 3.509e-04 | -7.96 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | 194 | 35 | 17758 | 1761 |
SPRED1,TBC1D1,FRMD6,RASA2,SDC4,KCTD12,CD274,SLC7A2,VASH1,PDGFB,OTUD1,RPS6KA2,RGS3,ZFP36,SLC44A1,BCL6,TNFRSF12A,CITED2,SNX10,TIPARP,C9orf72,SOCS5,B3GNT2,TNIP1,PLAUR,COQ10B,ARF4,STX3,OPTN,HLA-B,CSF1,FZD5,ST3GAL1,IFIH1,KLF7 |
| 3.509e-04 | -7.96 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_DN | 194 | 35 | 17758 | 1761 |
GCLM,GOLIM4,FRMD6,CD82,SLC25A13,EFHD2,IL18,REPS1,SPTB,RAD23A,NOV,ADRBK1,PIK3AP1,LMO4,BHLHE41,CDH3,MDFIC,ALDH7A1,TAGLN2,CTTN,PTPRE,MYLIP,PPIF,CPD,STAU2,NUBP1,MAP3K6,PSMA4,LEPR,BFSP1,PVRL2,PLK2,CGREF1,MAP3K5,HOXC13 |
| 3.517e-04 | -7.95 | NOTCH_DN.V1_UP | MSigDB lists | NOTCH_DN.V1_UP | 172 | 32 | 17758 | 1761 |
RUNX2,CRYM,ATP8A1,HABP4,ASB9,RAB23,TGFBR1,PRKACA,HPCAL4,SLC9A7,TTC21B,AIM1L,PAIP2B,KIF13B,KCNN4,PRKG1,RP2,IFIT1,NPTXR,LMAN1,RASGRP1,FARP2,DLGAP1,SSH3,GRIN1,TNS1,DGKE,DHX32,EPN3,PIAS3,BHLHB9,CLMN |
| 3.549e-04 | -7.94 | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | MSigDB lists | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 209 | 37 | 17758 | 1761 |
MYL9,SSH1,IQGAP1,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,PDGFA,ITGA3,ITGB8,PIK3CA,MYH14,PIK3CD,IQGAP3,PIKFYVE,F2R,TIAM1,PDGFC,SSH3,RHOA,PIK3R1,PIP4K2C,DIAPH2,EZR,BCAR1,MYL12A,ARHGAP35,FGFR2,LIMK1,ITGA7,ITGAV,ARPC2,MYL12B,FGD1,ARHGEF4 |
| 3.561e-04 | -7.94 | glutamate receptor binding | molecular function | GO:0035254 | 34 | 11 | 16491 | 1673 |
GNAS,CALM2,RASGRF1,PLCG1,CABP1,CALM1,DLG1,GRIN1,NETO2,CALM3,DLG3 |
| 3.585e-04 | -7.93 | AGC_KINASE_CTER | prosite domains | PS51285 | 55 | 15 | 11866 | 1235 |
RPS6KA2,ADRBK1,AKT1,CIT,RPS6KA1,STK38,SGK3,PRKG1,SGK1,PRKCQ,GRK6,PKN1,MAST4,PRKACA,ADRBK2 |
| 3.593e-04 | -7.93 | single-organism carbohydrate metabolic process | biological process | GO:0044723 | 646 | 93 | 16441 | 1675 |
GAA,UGT8,UGP2,GALNT12,SLC25A13,HEXB,NANS,MGAT5B,PRKACA,CALM2,MUC16,MUC4,IL6ST,IMPAD1,PIK3CA,FUT1,AKR1B1,GOT1,RPN2,LMAN1,PHKA2,TIPARP,MGAT5,NAGA,GM2A,SIRT1,SEC23A,AKT1,SLC35C1,GALNT7,MCFD2,IDH1,ARF4,IRS2,MAN2A2,ALDH5A1,DDOST,DOLPP1,GNPTAB,DHTKD1,GLA,ITPKA,ST3GAL1,MAN2B2,CMAS,PPP1R2,ENO2,GNE,CALM3,PDIA3,CTSZ,ISYNA1,B4GALT4,POMGNT1,ADAMTSL4,B4GALNT1,B3GALNT1,FUT2,CTSC,PTEN,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,PPP6R1,GCNT1,TRAK2,GFPT1,B3GALT6,B3GNT7,PGM1,B3GNT2,GCLC,CALM1,MGAT4B,GYLTL1B,PARP4,OGDHL,C1GALT1C1,COL7A1,PDK3,GLT8D2,CYB5A,GALNT3,FUCA1,ONECUT1,PRKAG2,UAP1,SERPINA1,PGM2L1,MDH1,CTSA |
| 3.595e-04 | -7.93 | regulation of cell-cell adhesion | biological process | GO:0022407 | 371 | 59 | 16441 | 1675 |
CASP3,NF2,SERPINE2,LGALS3,IL15,ITGA6,HLA-E,UBASH3B,ERBB2,IL18,CD274,TNFSF9,EFNB1,HLA-A,EPCAM,CDH1,IL6ST,BMP7,BCL6,PIK3CA,DLG1,PRKG1,FXYD5,IGFBP2,C10orf54,CITED2,WNT3A,SYK,RASGRP1,SOCS5,EPB41L5,HES1,CD55,RHOA,CELSR2,RIPK2,AKT1,ITCH,PIK3R1,PPARA,RGCC,PDE5A,PRKCQ,YES1,SOX13,CD83,SWAP70,PLPP3,SPINT2,TBX18,NR4A3,NOD2,EFNA5,PIEZO1,ICOSLG,NDFIP1,JAK3,RAP1GAP,L1CAM |
| 3.604e-04 | -7.93 | aminoglycan metabolic process | biological process | GO:0006022 | 175 | 33 | 16441 | 1675 |
SLC35D2,PAPSS2,HSPG2,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,CHPF,GNS,IMPAD1,XYLT2,PAPSS1,GALNS,PIM1,CHP1,B3GALT6,CHSY3,HMMR,B3GNT7,B3GNT2,AKT1,GUSB,GLCE,FUCA1,HS6ST1,HPSE,HS3ST3B1,ARSB,ST3GAL1,NDST3 |
| 3.617e-04 | -7.92 | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 31 | 17758 | 1761 |
CPD,KCNJ12,SEMA6B,OPLAH,PINK1,IGFBP6,REPS2,EPAS1,MPP1,SDC4,NENF,ALCAM,PCTP,CMTM6,LMNA,PIAS3,MARCH8,CTNNBIP1,ATP6V0B,CALD1,CABP1,HOXA9,MATN2,SORL1,ZDHHC7,PITPNA,NRG1,EIF4EBP2,LZTS1,CYBRD1,RRAGD |
| 3.619e-04 | -7.92 | FCERI mediated MAPK activation | REACTOME pathways | R-HSA-2871796 | 248 | 44 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,FOS,PSMA4,RASA1,IRS2,PLCG1,JAK1,PPP2R5A,FGFR2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 3.632e-04 | -7.92 | negative regulation of protein complex disassembly | biological process | GO:0043242 | 62 | 16 | 16441 | 1675 |
GAS2L1,ADD1,CKAP2,EPS8,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2 |
| 3.633e-04 | -7.92 | positive regulation of cell motility | biological process | GO:2000147 | 379 | 60 | 16441 | 1675 |
SEMA6B,ANXA3,LGALS3,ATP8A1,SOX9,RET,COL18A1,SELL,CD274,CAMK1D,HDAC6,PDGFB,ETS1,FBLN1,SRPX2,NRP2,HDAC9,PDGFA,EPCAM,DAPK2,CXCL16,ITGA3,IGF1R,CYR61,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,EPB41L5,DOCK4,SUN2,RHOA,AKT1,RAPGEF2,PIK3R1,ANO6,SYNE2,FURIN,EPHA1,BCAR1,DOCK5,GPLD1,IRS2,PLCG1,ONECUT1,SWAP70,SEMA4D,PLPP3,CSF1,FAM110C,ITGAV,GPER1,CFAP20,F2RL1,SEMA3A,HSPB1 |
| 3.648e-04 | -7.92 | negative regulation of multicellular organismal process | biological process | GO:0051241 | 967 | 131 | 16441 | 1675 |
SIGIRR,LGR4,TSC22D3,EPHA4,NDRG2,VASH1,PDGFB,FAM101B,DUSP10,TACSTD2,SEMA3G,ACVR1C,ITCH,EZR,ARHGDIB,F12,SAV1,ABR,DPYSL3,ENPP1,PLK2,HOXA9,TRAF3IP1,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,SEMA6B,SERPINE2,UBASH3B,SOX9,FBLN1,GATA2,VASN,PRKG1,SORL1,C10orf54,WNT3A,MYLIP,GPR161,SOCS5,PDE5A,NFIB,CDK5R1,GNAS,SEMA4D,NFKBIA,NLRC5,SFMBT1,STK39,GDF11,JAK3,SEMA3A,IFIH1,TOB1,RARG,XDH,GAS2L1,GRHL2,NLRX1,INPP5D,TP53,ERBB2,CD274,PRKACA,PDGFA,SVBP,NOV,SP100,BCL6,CDKN1B,CDH3,DIXDC1,TWIST1,DAB2IP,NOTCH3,PDE4D,LGMN,ETV4,F2R,SEMA3B,DOCK4,PTGER4,DOCK5,FZD7,ATP1A1,AXL,CORO1C,INPP4B,NRG1,NKX3-1,ADGRG1,CIT,LRP4,HERC5,TGFBR1,TRIB2,GSTP1,SIX4,ADGRB2,RNF128,ADRBK1,ADORA1,PTEN,BMP7,CST3,KIAA0319,MAPK11,TRIM62,HES1,RHOA,PLAUR,RAPGEF2,ASPM,PIK3R1,RGCC,FURIN,PRICKLE1,BBS2,CD83,PRDX4,BANK1,ACVRL1,TWSG1,NMI,TBX18,ARRB1,OSR1,SOX8,NDFIP1 |
| 3.649e-04 | -7.92 | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | 187 | 34 | 17758 | 1761 |
SORBS1,ARMCX3,EPAS1,ZCCHC24,ETV5,PDIA5,KIF23,NDUFA4,SNN,SEPP1,PDIA4,SCML1,TNS3,BHLHE41,MITF,DAPK1,DUSP10,CLIP2,OSGIN1,SOCS5,LOC81691,MRPS33,KLHL2,DCTN6,FECH,GALNT3,MFAP3L,TMEM164,H1F0,HNRNPH2,PPM1H,SH3BP4,SERPINB6,HSPB1 |
| 3.657e-04 | -7.91 | tube formation | biological process | GO:0035148 | 140 | 28 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SOX9,SDC4,RET,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,NFIB,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,DAB2IP,SOX8,OSR1,RARG,COBL,DVL2 |
| 3.671e-04 | -7.91 | regulation of neuron differentiation | biological process | GO:0045664 | 507 | 76 | 16441 | 1675 |
FOXO6,SSH1,RET,EPHA4,PLXNA1,CAMK1D,NCS1,DPYSL2,BCL6,DAB2IP,DIXDC1,CTTN,NOTCH3,SEMA3G,PACSIN1,TIAM1,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,ARHGAP35,DPYSL3,GPRC5B,BHLHB9,PTK7,LIMK1,PLK2,SIPA1L1,EFNA5,NRG1,ITPKA,ARF6,COBL,LZTS1,GRN,BIN1,SEMA6B,SERPINE2,CIT,LRP4,ETV5,SOX9,CRABP2,ITGA3,PTEN,GATA2,BMP7,KIF13B,MYCL,MEGF8,KIAA0319,TNFRSF12A,WNT3A,RIMS2,CCDC88A,TLE6,HES1,TGIF1,RHOA,MMD,ASPM,RAPGEF2,GRIN1,HMG20B,CDK5R1,CDK5RAP1,PTPRF,SEMA4D,TMEM30A,GDF11,SOX8,ARSB,SEMA3A,L1CAM |
| 3.673e-04 | -7.91 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 537 | 78 | 17758 | 1761 |
CCNI,NQO1,GALNT12,FAM102B,IL27RA,NENF,FAM101B,SLC20A1,PHLDA1,TNFSF9,NCS1,SH3KBP1,ZDHHC12,SLC44A1,SERINC2,MINPP1,LMAN1,TIAM1,RASGRP1,LAMP3,SULF2,CD55,LYRM1,CBX6,ACO1,ATP1B1,DUSP4,CD40,DOCK5,ALCAM,LIMK1,P4HA2,PNPLA6,RAB11FIP1,SLC27A3,ISOC1,MAFF,NFKBIE,GTF3A,TGFBR1,KIF5B,AKIRIN1,MARCH8,CD109,B3GALNT1,LYPD3,SPIN4,BHLHE41,KCNN4,CALD1,COL6A1,RANBP1,TAGLN2,FAR2,MCCC2,MYO5A,ABCC1,FAM69A,SUN2,PDGFC,HPS3,PLAUR,HMG20B,AK4,GGH,FNDC3A,BCAR3,SLC6A6,ETS2,MFSD2A,CSF1,ITPR1,NETO2,DTX4,NR4A3,MAP3K5,TBC1D4,ACOT7 |
| 3.676e-04 | -7.91 | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | MSigDB lists | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | 373 | 58 | 17758 | 1761 |
SLC35D2,SCN5A,SLC25A24,KLK10,SSH1,LGR4,CDH22,KLHL13,SLC25A27,EFHD2,PBX3,TGFBR1,BCL2L1,SNN,SLC20A1,PDGFB,TEAD3,RAB15,MGAT4A,FRAS1,OSBPL3,ADAM15,SNX16,CRY2,KLF9,C8orf58,RASGRP1,ATP2B1,XKR8,IGDCC4,MDFI,CPD,FZD4,ACVR1C,PTPRU,DIAPH2,C15orf39,CCNF,FNDC3A,NPHP3,STX3,SOX13,IRS2,PLEKHG6,NCOA3,SLC4A4,SYT7,GNPTAB,NKD1,LRIG1,TSPAN18,PGM2L1,PCDH19,YOD1,HMGA1,CPEB2,NIPA1,NXT2 |
| 3.682e-04 | -7.91 | thyroid-other-neoplasm | COSMIC cancer mutations | thyroid-other-neoplasm | 8018 | 860 | 17775 | 1757 |
HECA,ACACB,KLK10,IL15RA,HEXB,RET,CACNA2D2,NRG2,LACTB2,BARD1,CARD10,LTBP3,GRM5,ZNF275,EPDR1,CALM2,DAPK2,WEE1,MUC4,KIAA1107,CYP2S1,ALDH1A3,TUBG1,CLDN4,SEMA3G,TINAGL1,PIK3CD,ACOX2,TIAM1,TIPARP,MGAT5,DNAAF3,NWD1,SPEF2,SMARCA2,FBXL16,MTRF1L,PRKAR2B,LOXL2,F12,PPP1R14C,CYP4F3,COL12A1,PGF,ENPP1,CARHSP1,PLCG1,DNM1L,ANKRD6,LIMK1,ATP7B,TRAF3IP1,FAM114A1,NOD2,SERPINB6,E2F8,GAB1,NXT2,SCN5A,ITGA6,SOX9,GPSM2,FAM21C,MERTK,HPCAL4,LMNA,RABGGTA,ATG4A,ELF3,FRY,FAM189A1,MEGF8,FLRT3,PCYOX1,MAP3K9,ALPK1,PANX2,ULBP2,DGKG,PPP6R1,HPS3,SLC37A1,SALL4,STAT4,MYBL2,ELK1,NPHP3,PCTP,GNA11,DCP2,PLIN5,PTPRF,NCOA3,SLC4A4,ETS2,ITPR1,RAET1L,S100A5,AURKA,DRP2,TMEM173,XDH,ADAMTS16,EGLN1,DOCK9,TPRN,RNF224,PAPSS2,ACTR8,PKP2,PRSS22,GRK6,APC2,CCND1,ST5,MUC16,SCNN1A,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,ZNF365,MYT1,SCN3A,MX1,CAMSAP3,C6orf1,COL6A2,APOBEC3D,SYNE2,CYS1,CDCA2,RAB38,ZNF618,IRS2,SHROOM3,WFS1,AXL,SIPA1L1,PLEKHG1,INPP4B,PNPLA6,ISOC1,MAPK12,TTC8,TNRC6C,SDC4,HABP4,RASSF7,BTN3A1,PDIA3,ANO9,PKN1,NUCB2,HOXB2,NEO1,DTX3L,CXCL16,ADD3,FUT2,IGSF9,ANKS1B,CALD1,CST3,KLC3,ADAM15,WWP1,MAPK11,NPTXR,CRTAP,PARP9,AMOTL2,ADAMTS2,LCA5,TACC1,FMN1,RAPGEF2,MFSD2B,PIK3R1,NUB1,MRS2,GRIN1,MYEOV,AK4,BLVRA,CRISPLD2,CNTNAP1,PITX2,RAB11FIP2,SYT7,ITGAV,CENPE,CMPK2,ACOT7,CYBRD1,TMEM131,UNKL,SIGIRR,ILDR1,TRIM2,KIAA1462,EPAS1,GNPDA1,EPHA4,FHDC1,ARFGEF1,NDRG2,DNAJB11,ITPR2,TP53I11,MGAT5B,HDAC6,NUP62CL,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,MKRN3,PAPSS1,ABCA2,TMEM143,TLN2,TRAM1,DDX59,NEB,S100A13,CCDC38,ZNF462,PLK1,THRB,ING1,CELSR2,CITED4,CR2,EZR,ARFRP1,ANLN,PRKRA,IDH1,SESN1,DZIP1L,HS6ST1,PLEKHG6,KCNMB4,AGPAT2,MAP2,DOLPP1,HOXA9,RAB11FIP1,PRKCDBP,ARRDC1,KLF11,PIK3C2B,PIEZO1,GLCCI1,PRKAA2,RMND5A,RUNX2,LGALS3,HJURP,DNAJB2,RASA2,HLA-F,PDCL,ADCK5,HES2,CNTNAP2,B4GALT4,ANO1,B4GALNT1,TNS3,DAZAP1,RINL,GATA2,FRAS1,AHCY,FAR2,PLCB2,CKAP4,CYP26B1,CHSY3,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,CORO2A,ZNF320,SPATA13,SCRIB,EIF2AK1,TCF7,PRX,FOXD2,RASGRP2,MAPKAPK2,COL13A1,ITGA7,PRPS2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,RNF146,USP43,AVPI1,HOXB7,UPF3B,XYLT1,TP53,ERBB2,LPIN3,STIL,SYTL2,PDGFA,LHX6,PLCG2,N4BP3,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,MINPP1,CTDSP2,DVL2,SULF2,CTH,SIRT1,PPIF,TMTC1,CLCN3,AKT1,CDC20,PTGER4,ACO1,DAG1,ATP13A2,DUOX1,PRRT4,RBL1,ABHD12,MMP17,PTK7,STK38,ADAMTS14,IRF7,ANXA9,SYT13,AIFM3,ST3GAL1,NDST3,MAN2B2,BIN1,COL9A3,PINK1,PACSIN2,GOLIM4,CDH22,MACC1,PSMD10,GTF3A,GDF15,LBR,AIP,PARM1,VPS26A,DNAJB9,SH2D4A,SIRPA,NRP2,M6PR,ALPP,FAM63A,TFAP2A,ABCD1,SYK,GCNT1,IGDCC4,WBP5,DLGAP1,NFE2L3,HES1,PSMB4,GUSB,AMFR,PLAUR,PPARA,MAML2,COL7A1,GGH,BCAR1,RNPEP,TXNDC11,MAPK8IP1,FUCA1,BANK1,SMTNL2,FAT4,SERPINA1,NMI,ICOSLG,NDFIP1,UBE2C,TBC1D4,DIS3L,GOLGB1,SUN1,GAA,SSH1,HSPG2,LGR4,VANGL1,TAP1,PPFIBP2,PSME1,NANS,PLXNA1,CCNB1,PJA2,OAT,VASH1,FAM101B,SLC9A7,TYMP,CYP1A1,ANKS6,IQCE,RGS3,IL31RA,FOSB,SERINC2,PIK3CA,ATRNL1,MTMR11,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SPATA18,SNTB2,HSPA12A,CASP9,NBPF3,KIF13A,TNS1,GALNT7,MCFD2,SLC25A5,ZFAND5,POR,SPNS3,ARHGEF26,AHRR,ANKRD10,SLC25A4,PLK2,GNPTAB,LRIG1,PRDM5,FAM110C,BMP1,DHTKD1,NFKBIZ,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,MRC2,FRMD4A,CDKN1C,TBC1D1,HLA-E,DGKQ,C6orf106,TNFRSF19,KIAA1161,BMP2K,MECOM,DOPEY2,ITGA3,SNX18,LYPD3,ZNRF2,PIK3AP1,BHLHE41,VASN,SLC16A6,AIM1,RUNDC3B,DAPK1,ADCK2,SORL1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,RIMS2,IGSF3,SOCS5,TRAK2,EPB41L5,PRODH,KCNJ12,KLK5,MMD,MFI2,TBC1D8B,ADCK3,AMER1,ANO6,PIP4K2C,VEZT,ATP8B3,ANTXR1,RASA1,FRMD4B,DGKH,GABRD,SLCO4A1,PLEKHH2,PRKAG2,TJP3,FAAH,DCK,SLC4A3,FAM83D,AGBL5,FGD6,PCDH19,NR4A2,KLK7,CABIN1,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,FRMPD3,MFSD3,SPRED1,FOXO6,CEP70,TCTN2,NLRX1,ST14,RPS6KA1,DDIT4L,CCDC110,BROX,ATP2C2,TMEM170B,AIFM2,DDR1,MNS1,EPS8L2,APOBEC3B,NOV,TRANK1,FAM46A,CNNM4,CDKN1B,EPHB4,LGMN,GPX4,ATG4D,MYO5B,SEC23A,CAPN6,FOXJ2,DRAP1,CYB5R2,PANK1,UTRN,KIF1C,PRKCQ,SLC11A2,PYGO1,PKMYT1,C15orf39,ITPR3,ALCAM,ATP10D,FZD7,ZNF469,NIN,PRDM11,EPHA10,AMZ2,DDOST,JAK1,TRIOBP,FAM195A,NRG1,HS3ST3B1,SLC27A3,PRR15,COBL,DENND5B,WASF3,PCOLCE,HAPLN3,CENPI,CYB561,APOBEC3H,SEPP1,DNAH3,LGALS3BP,TEAD3,HLA-A,SIX4,WWP2,TMCC3,E2F7,TMEM87B,PTEN,FJX1,CITED2,CNPY3,SLC16A5,SPRY2,TRIM62,OSGIN1,NCOA2,FARP2,RASGRF1,SHMT1,ARHGEF28,ALDH2,ZC3H11A,FURIN,ZKSCAN2,PARP4,DIAPH2,C2orf69,LRRC1,FOS,GPLD1,NUCB1,ACADSB,FGFR2,TBX18,ABCB1,PGM2L1,ERAP1,GRIN2D,ETAA1,WDR62,FZD5,NCAPG2,ARSB,ESPL1,CXorf56,MELK,ESYT2,RGMA,JARID2,EXPH5,EMX1,UGT8,HEBP1,VARS2,ERP29,KREMEN1,DENND2D,TSEN34,PTCHD4,HTR1D,ABCD4,CHPF,ARHGEF10L,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,IMPAD1,CEP78,DLG1,ANKRD12,POF1B,RAB20,RP2,MYH14,CTTN,TECR,PTPRE,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,ASCL5,ITCH,RGAG1,ROR1,PTGFRN,TYSND1,STK17B,MDK,MAN2A2,ARHGEF19,GPRC5B,MADD,ZNF165,ADIPOR1,RAP1GAP,CPPED1,GRN,LASP1,ARAP3,LRRFIP2,ZNF395,SERPINE2,PEX6,SAMD9,PM20D2,FAM81A,PHLPP1,ADAMTSL4,AIM1L,ZNF432,OTUD1,KCNN4,COL6A1,FXYD5,LIMCH1,C10orf54,HLA-C,RFX5,NCEH1,ZRANB1,ETV7,ALS2CL,TPGS2,KDELR1,PODXL2,GYLTL1B,BTN3A2,PDIK1L,MFSD7,RANBP9,AMDHD1,FECH,GNAS,SLC6A6,TMEM30A,CGREF1,NFKBIA,SH3BP4,RHOBTB2,ALPK3,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,GAS2L1,LMO7,NCKAP5,DYNLRB1,SLC25A24,HDAC11,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,SETDB2,CYP4F11,ZDHHC12,FRYL,KIF14,RPN2,ECE1,F2R,PDIA6,MAP3K3,SUSD3,ZNF525,PTPRU,IGSF8,ERBB2IP,DOCK5,ARHGAP35,BHLHB9,SECTM1,PEX2,VSIG10,SPTBN5,REEP4,LNP1,ABCA1,GLIS3,FBLIM1,SORT1,ENO2,ARHGEF11,FRMD6,LRP4,FAM134A,MIER3,AES,COL4A5,INTS8,SBF1,NTAN1,FAM167A,HDAC9,SAC3D1,IRF2BPL,IL17RB,TOP2A,CARD8,MDM1,ADORA1,TAF1B,MLPH,LLGL2,A4GALT,BMP7,GALNS,RRBP1,KIAA0319,ARVCF,IQGAP3,CLIP2,MYO5A,SUN2,NR4A1,OGDHL,RUNX3,LEPR,ENDOD1,KLHL2,HLA-B,C2orf70,TRIM69,SPINT2,ARRB1,HOXB13,GRAMD1C,SOX8,PLOD3,ZMIZ1,AHR,L1CAM,RAB3IL1,ABCG1,SNPH |
| 3.692e-04 | -7.90 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 89 | 20 | 17758 | 1761 |
BCAM,REPS2,ST14,SOX9,PDIA5,TP53,EIF2AK1,GDF15,GALNT7,ELK1,TRIM68,ARHGEF26,EPCAM,UAP1,LRIG1,ALDH1A3,ECI2,TSPAN13,RAP1GAP,TBC1D4 |
| 3.692e-04 | -7.90 | KEGG_PROSTATE_CANCER | MSigDB lists | KEGG_PROSTATE_CANCER | 89 | 20 | 17758 | 1761 |
CCNE2,PDGFC,NKX3-1,AKT1,CASP9,PIK3R1,TP53,ERBB2,TCF7,PDGFB,GSTP1,PDGFA,CCND1,IGF1R,PTEN,FGFR2,NFKBIA,PIK3CA,CDKN1B,PIK3CD |
| 3.694e-04 | -7.90 | regulation of dephosphorylation | biological process | GO:0035303 | 154 | 30 | 16441 | 1675 |
CAMSAP3,SPRED1,PINK1,LMTK3,PPP4R4,PPP1R2,NUAK1,IQGAP1,CALM1,CALM3,CDCA2,PKMYT1,TIPRL,SH2D4A,PPP2R3A,SYTL2,GPLD1,CALM2,SWAP70,ADORA1,PPP2R5A,NPNT,SEMA4D,CRY2,SLC39A10,DLG3,PPP2R2D,PPP6R1,ARFGEF3,CHP1 |
| 3.695e-04 | -7.90 | negative regulation of protein kinase B signaling | biological process | GO:0051898 | 34 | 11 | 16441 | 1675 |
SIRT1,BANK1,PTPRJ,IGF1R,PTEN,DLG1,PRKCDBP,GPER1,PHLPP1,DAG1,XDH |
| 3.701e-04 | -7.90 | ATAAGCT,MIR-21 | MSigDB lists | ATAAGCT,MIR-21 | 109 | 23 | 17758 | 1761 |
RMND5A,THRB,ACBD5,NF2,EPHA4,PIK3R1,PPARA,NFIB,ARHGAP24,PITX2,AP1AR,TIMP3,ZNF367,MATN2,ZNF704,YOD1,WWP1,OSR1,GLCCI1,BTBD3,SPRY2,RASGRP1,EHD1 |
| 3.753e-04 | -7.89 | organic acid metabolic process | biological process | GO:0006082 | 1002 | 135 | 16441 | 1675 |
ACACB,SLC35D2,UGT8,HSPG2,AASS,CRYM,CPT2,HEXB,VARS2,OAT,SDC1,CHPF,CYP1A1,CYP2S1,IMPAD1,ALDH1A3,PAPSS1,SERINC2,ACOX2,TECR,CYP1B1,PRKAR2B,ICMT,IDH1,MRPS36,CYP4F3,POR,HS6ST1,ENPP1,HPSE,UEVLD,P4HA2,DHTKD1,ADIPOR1,PRKAA2,FAM213B,ALDH6A1,ABCG2,SLC1A3,B4GALT4,GNS,PCYOX1,AHCY,GAD1,MCCC2,ABCC1,CYP26B1,GFPT1,CHSY3,FADS2,B3GNT7,PRODH,ERO1A,PDK3,AMDHD1,CYB5A,GLCE,MAPKAPK2,SLC6A6,PRKAG2,FAAH,MDH1,EGLN1,PLA2G4A,UGP2,PAPSS2,XYLT1,MGST2,SLC7A2,LPIN3,CYP39A1,CYP26A1,XYLT2,FABP6,SRR,GOT1,ACSL4,MINPP1,EGLN3,SULT2B1,SULF2,GPX4,CTH,PANK1,ACO1,GLO1,ALDH5A1,ABHD12,PEX2,SLC27A1,CYP2U1,HS3ST3B1,ST3GAL1,SLC27A3,LTA4H,NDST3,CMAS,GCLM,ENO2,GNE,SDC4,HAL,DSE,CRABP2,SPR,SGPL1,SLC27A6,GALNS,ECI2,ATP8B1,ABCD1,ALDH7A1,SYK,MYO5A,CRTAP,NCOA2,FAH,B3GALT6,PGM1,B3GNT2,SHMT1,PLSCR1,GCLC,ELOVL3,PPARA,OGDHL,GGH,RNPEP,PRDX4,ACADSB,NR4A3,ARSB,PTGES,ACOT7,OCLN |
| 3.770e-04 | -7.88 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 12377 | 1285 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,DPP8,CARD10,LTBP3,ZNF275,GRM5,MUC4,UBE2T,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,TMEM151A,TFAP2C,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,NOD2,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,FAM21C,HPCAL4,RABGGTA,FRY,PAIP2B,ATP5H,MEGF8,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,DGKG,ULBP2,NUP85,PPP6R1,HPS3,PQLC3,ELK1,NPHP3,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,REPS1,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,SEPT6,DNAJB14,GTF2A2,ZNF618,GABARAPL1,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,KLC3,ZFAND4,FAM102A,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,CNTNAP1,RPL12,RAB11FIP2,SYT7,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,KCNMB4,AGPAT2,ARRDC1,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,AHCY,SELK,PIM1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,RGMB,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,TMX4,TP53,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,STK38,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,PINK1,CDH22,CPEB4,KLHL13,HAL,ERI2,GTF3A,AIP,LBR,PARM1,H1FX,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,TFAP2A,GTF2F2,TRIM21,TSPAN13,SYK,ATP2B1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SCG2,ICOSLG,PTGES,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,SSH1,TSC22D3,CAMK1D,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,TACSTD2,ARMCX6,ACVR1C,SLC35C1,KIF13A,LDB2,PRIM1,ANKRD10,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TMEM55B,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,RPL39,AIM1,DAPK1,PRKG1,TMEM51,ADCK2,TPST1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,ATP8B3,ANTXR1,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,RALBP1,DDIT4L,ATP2C2,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,ACAP2,TRANK1,EPHB4,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,TRIOBP,SLC27A3,PRR15,CBX7,HAPLN3,CENPI,EPS8,HERC5,PBX3,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CCDC82,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,UGT8,VARS2,MPP5,ERP29,TRIM68,HTR1D,ZFYVE16,SIPA1L2,HSF2,ARHGEF37,METTL7A,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,LAMP3,ITCH,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,PDE5A,HEATR5A,NUBP1,C3orf58,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,LMO7,DYNLRB1,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,ZNF687,CYP4F11,KIF14,DIXDC1,EPB41L4B,SEPHS1,PTPRU,C3orf52,CD40,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,ADD1,IL15RA,MRPS15,AASS,DNAJC3,CACNA2D2,DHX8,NRG2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,MANF,ACOX2,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,SERTAD4,LOXL2,F12,CYP4F3,COL12A1,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,ARF6,E2F8,GAB1,ALDH6A1,MERTK,LMNA,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SETD3,ITPR1,AURKA,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,ACTR8,RGS20,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,ZNF385B,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,PLEKHO1,SYNE2,NUSAP1,CDCA2,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,NKX3-1,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,GSTP1,ETS1,HOXB2,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ALG13,CALD1,ADAM15,ECI2,MAPK11,NPTXR,SGCB,TPCN1,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,GRIN1,MYEOV,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,FHL1,HMGA1,CENPE,MYL9,UNKL,SIGIRR,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,NDC80,TP53I11,HDAC6,SDC1,SHC3,MKRN3,ELF5,DUSP10,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,ZBTB7B,DPYSL3,PLCH1,MFAP3L,MAP2,P4HA2,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,NF2,UGP2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,ABRACL,RAD23A,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,SCN2A,DVL2,GM2A,CPD,SIRT1,TMTC1,CDC20,MYL12A,DUOX1,DNAJC10,PRRT4,ATP1A1,PTK7,ADAMTS14,ANXA9,C1orf43,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,CD63,MACC1,RUSC2,GNE,GABRG2,PSMD10,SELL,NKRF,DSE,SIRPA,SLC9A2,PPP2R3A,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,BANK1,FAT4,SERPINA1,ZNF214,NAT1,TMC5,CDCA7L,NMI,NETO2,PGRMC1,FAM117A,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,SESN3,CTGF,ELMO2,ZFP36,IQCE,PRICKLE3,RGS3,IL31RA,AOX1,ATRNL1,MTMR11,RCAN3,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SLC25A5,ZFAND5,TP53I3,SPNS3,AHRR,PTER,GNPTAB,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,KIF23,ISYNA1,SLC1A3,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,BDH1,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,DDB2,MFI2,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,DCK,SLC4A3,FGD6,PCDH19,MAP3K5,NRBP1,FRMPD3,PLA2G4A,CEP70,ARMCX3,TRIP10,NLRX1,CAST,IQGAP1,BROX,KCTD12,RNF182,CD274,SNN,MNS1,APLP2,ZNF75D,FAM46A,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,CCNJL,APOBEC3H,SPR,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,MPP1,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,PGM2L1,GRIN2D,SLC25A38,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,CPT2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,RAB20,RP2,MYH14,SLC39A10,RASGRP1,ATL1,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,LRRC42,ZNF114,ARHGEF19,UEVLD,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,OTUD1,AIM1L,CA2,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,HMG20B,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,SLC6A6,UTP14C,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,EGFL7,PITPNA,PROM2,GAS2L1,SLC25A24,IL15,MORC4,TDRKH,ARHGEF16,LRRC45,SETDB2,ZDHHC12,FRYL,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,PEX2,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,ASPM,DEPDC4,LRRC66,OGDHL,KLHL2,HLA-B,PRCP,HNRNPH2,GEM,L1CAM,SNPH |
| 3.776e-04 | -7.88 | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 11 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 3.776e-04 | -7.88 | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 11 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 3.776e-04 | -7.88 | papilloma | COSMIC cancer mutations | papilloma | 35 | 11 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 3.777e-04 | -7.88 | MODULE_257 | MSigDB lists | MODULE_257 | 151 | 29 | 17758 | 1761 |
CAMSAP3,PACSIN2,ELK3,AKT1,TBC1D1,DNAJC3,OXR1,ARL4C,LITAF,HMG20B,GABRG2,SLC35C1,TCF7,TGOLN2,SLC7A2,SLC20A1,TP53INP2,EPS8L2,CHPF,MMP15,GNS,APLP2,CA2,ADRBK1,CALD1,LIMK1,PLK4,ECE1,EHD1 |
| 3.784e-04 | -7.88 | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | 180 | 33 | 17758 | 1761 |
SLC35D2,CD82,CDKN2C,WEE1,KCNN4,SLC16A6,MGAT4A,LMO4,OSBPL3,BHLHE41,PASK,PAPSS1,AIM1,PDE4D,FAIM,CLIP2,CRTAP,GFPT1,PQLC3,BTNL9,GCLC,SYBU,PARP4,RAD17,RNF19B,DGKE,FAS,TWSG1,CLIP4,FGD6,GRAMD1C,SLC27A3,TMEM14A |
| 3.784e-04 | -7.88 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | 180 | 33 | 17758 | 1761 |
UGP2,IL15RA,SDC4,CD274,SLC1A3,OSR2,CCNB1,IER3,BTG3,E2F7,ITGB8,SNX18,PIK3AP1,FJX1,DRAM1,SNX10,RIPK2,RAPGEF2,CD40,SAV1,RNF19B,CDK1,SOCS3,CD83,NIN,PTPRJ,NFKBIA,SLC2A6,RAP2C,NFKBIZ,HS3ST3B1,IFIH1,EHD1 |
| 3.796e-04 | -7.88 | RAO_BOUND_BY_SALL4_ISOFORM_B | MSigDB lists | RAO_BOUND_BY_SALL4_ISOFORM_B | 496 | 73 | 17758 | 1761 |
ARHGAP11A,CASP3,VANGL1,CNOT8,EPHA4,CCDC68,CD274,MORF4L2,OSR2,BARD1,CENPN,NKAIN3,RCN1,LMO4,STEAP2,CLDN4,SNX16,CLCN3,CD55,FIGNL1,NFE2L1,KIF13A,PIF1,ANLN,ANKRD10,HLF,ANKRD6,GDE1,HS3ST3B1,MYL12B,CBX7,DDX58,RMND5A,CMAS,GCLM,ARHGEF3,PACSIN2,CENPI,RUSC2,HABP4,ETV5,ABCG2,TNFRSF19,LBR,HMGXB4,SLC25A36,HDAC9,ITGA3,OSTF1,KLF9,CITED2,ZRANB1,GAD1,ALDH3A2,CCDC88A,SOCS5,TGIF1,HES1,B3GNT2,SALL4,TCEAL8,BCAR1,C3orf58,G2E3,DCTN6,PITX2,NAT1,TBX18,SH3BP4,MAP3K5,CPEB2,RNF146,DIS3L |
| 3.805e-04 | -7.87 | MAPK1/MAPK3 signaling | REACTOME pathways | R-HSA-5684996 | 234 | 42 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,IL6ST,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,CDK1,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 3.806e-04 | -7.87 | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | MSigDB lists | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | 46 | 13 | 17758 | 1761 |
DDX58,MX1,DTX3L,HLA-B,SP100,CD9,IRF7,TGFBR1,SAMD9,IFIT1,OAS3,HERC6,IFI6 |
| 3.810e-04 | -7.87 | V$IRF7_01 | MSigDB lists | V$IRF7_01 | 240 | 41 | 17758 | 1761 |
DDX58,PARP12,TAP1,ERBB2,PSME1,PHLPP1,SRPX2,LGALS3BP,FOXP2,DTX3L,CXCL16,ARTN,CALD1,LYPD6,LHX6,BCL6,TRIM21,IRF2,RFX5,PIK3CD,PDE4D,ARMCX6,RASGEF1A,PDGFC,PCGF5,USP18,SAT1,KIF13A,LDB2,FOS,COL12A1,OPTN,NFIX,PITX2,TAPBP,C19orf66,RBL1,SIPA1L1,NR4A3,NR4A2,ARF6 |
| 3.854e-04 | -7.86 | testis | COSMIC cancer mutations | testis | 761 | 104 | 17775 | 1757 |
TRIP10,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,DAPK2,WEE1,RPS6KA2,SP100,PIK3CA,PLK4,EPHB4,NEB,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,PRKAR2B,ROR1,PKMYT1,IDH1,MAP3K6,STK17B,ADRBK2,ABR,EPHA10,DUOX1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,BMP1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,ISYNA1,PKN1,TRIB2,DSE,MERTK,BMP2K,SNTA1,TMEM87B,IGF1R,ADRBK1,CDK16,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,SYK,MYO5A,ABCC1,ADCK3,TESK1,ASPM,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,RANBP9,BSDC1,STK17A,GNAS,MAPKAPK2,ACVRL1,FGFR2,PRCP,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK,GOLGB1 |
| 3.861e-04 | -7.86 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 11513 | 1202 | 17775 | 1757 |
HECA,AK7,HEXB,RET,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,FBXL16,CDA,PRKAR2B,RNF19B,ABR,ENPP1,PLCG1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,FAM21C,RABGGTA,MARCH8,TFAP4,FRY,MEGF8,FLRT3,RANBP1,MAP3K9,CADPS2,ALPK1,PANX2,MYLIP,DGKG,NUP85,MCCC2,HPS3,ELK1,NPHP3,SFXN5,PSMA4,GNA11,CACHD1,SLC4A4,ETS2,RAET1L,CLMN,GDF11,TMEM159,RUSC1,ADAMTS16,DOCK9,NQO1,CD82,GRK6,MGST2,REPS1,RCN1,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,TMEM200B,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,HTATIP2,XRCC6BP1,ZNF618,SNX12,PDLIM3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,MAPK12,CTHRC1,CKAP2,HABP4,BTN3A1,SLC25A43,BEX2,CTNNBIP1,DIRAS3,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,FAM102A,MED22,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,CXorf57,AK4,CNTNAP1,PLOD2,SYT7,PPM1H,ITGAV,OSR1,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,NTN4,SCARA3,PLK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,KLF12,KLF11,RRAGD,RMND5A,PARP12,RUNX2,HJURP,RASA2,ADCK5,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,PIM1,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,COL13A1,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,USP43,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,RBL1,ABHD12,STK38,SYT13,ZMAT1,BIN1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,LBR,PARM1,H1FX,NRP2,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,COL7A1,RNPEP,BBS2,DGKE,SMTNL2,SCG2,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LGR4,HSPG2,SSH1,VANGL1,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,FGD1,MRC2,TBC1D1,S100A2,TSPAN7,MESDC2,DOPEY2,RALGPS2,AIM1,DAPK1,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,KCNJ12,PRSS23,ADCK3,LPGAT1,ATP8B3,ANTXR1,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,THRA,DDIT4L,ATP2C2,FTH1,DDR1,CYP39A1,ZFYVE9,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,PDE4D,TSPAN1,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,UTRN,KIF1C,PKMYT1,PYGO1,ATP1B1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,CCDC149,TSPAN18,TRIOBP,SLC27A3,COBL,CBX7,IGFBP6,HAPLN3,EPS8,HERC5,FBXO6,DNAH3,EFNB1,HLA-A,SCML1,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,FARP2,TGIF1,PDGFC,ALDH2,B3GNT2,LONRF3,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,FZD5,WDR62,ESPL1,MELK,DEF6,UGT8,VARS2,MPP5,TRIM68,ZFYVE16,RAB15,SIPA1L2,ARHGEF37,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CYP1B1,NLRP4,USP18,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,ZNF165,CAPN1,PCSK5,ARAP3,SERPINE2,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,ELK3,PODXL2,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,LMO7,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,EPB41L4B,ECE1,PTPRU,GLO1,CD40,FANCE,CASP4,TLE1,SPTBN5,ABCA1,GLIS3,GCLM,ENO2,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,RAP2C,SPINT2,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,ACACB,KLK10,ADD1,AASS,MRPS15,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,LOXL2,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,ARF6,E2F8,GAB1,ALDH6A1,SLC36A4,MERTK,LMNA,ELF3,RAVER2,FAM189A1,FAM13B,NEK2,NCAM1,C9orf72,SALL4,STAT4,MYBL2,SPTLC2,DCP2,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,RNF220,SP100,DACT1,ACSL4,ARL4D,CDKN2D,SCN3A,ENPP4,SSH3,CAMSAP3,FZD4,SYNE2,NUSAP1,CDCA2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TNRC6C,PDIA3,ANO9,PKN1,GSTP1,ARHGEF40,ETS1,TIPRL,SRPX2,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,PLEKHF1,ADAM15,MAPK11,TPCN1,S100A6,AMOTL2,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,CYBRD1,DCBLD1,UNKL,TRIM2,FAM199X,CUL4B,EPHA4,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,ZNF462,PCGF5,CD55,ING1,MCTP1,EZR,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,EPB41L4A,PRKAA2,ZCCHC24,UBASH3B,CNTNAP2,IL18R1,DAZAP1,IGF1R,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,CORO2A,SPATA13,EIF2AK1,ANKRD29,G2E3,MAPKAPK2,EPN3,COQ10A,CSF1,MFSD2A,ITGA7,LTBP2,IFI6,RNF146,AVPI1,NF2,UPF3B,FOXM1,XYLT1,ERBB2,SLC7A2,LPIN3,CYP26A1,RAD23A,EFR3A,PLCG2,N4BP3,SCN2A,CTH,CPD,SIRT1,MBP,FIGNL1,CDC20,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,C1orf43,LTA4H,AIFM3,NDST3,ZNF701,CMTM4,MAN2B2,GOLIM4,CD63,MACC1,RUSC2,GABRG2,PSMD10,NKRF,DSE,SIRPA,SLC9A2,PPP2R3A,BUB1,KLF9,TLE6,IGDCC4,DLGAP1,HMMR,PSMB4,NR3C1,AMFR,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,SCRN2,CD83,BANK1,FAT4,SERPINA1,TWSG1,TMC5,NETO2,FAM117A,CLIP4,PPP2R3C,SPCS3,TBC1D4,NDFIP1,DIS3L,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,PLXNA1,SLC20A1,NCS1,CTGF,ELMO2,ZFP36,IQCE,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,RCAN3,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,PBK,HSPA12A,CASP9,NBPF3,TNS1,MCFD2,SLC25A5,SPNS3,ARHGEF26,HLF,SLC25A4,RBM47,PLK2,GNPTAB,PTER,DHTKD1,UNC5B,TANC2,TRAF5,LZTS1,DDX58,CDK17,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,C6orf106,ISYNA1,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,PIK3AP1,BDH1,RUNDC3B,OPN3,SORL1,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,FADS2,B3GNT7,PMPCB,DDB2,ZNF84,TBC1D8B,MICB,AMER1,ANO6,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,SLC2A4,ARMCX3,CEP70,NLRX1,S100A11,TRIP10,CAST,IQGAP1,RPS6KA1,BROX,KCTD12,RNF182,CD274,AIFM2,MNS1,TMPRSS4,APLP2,FAM46A,CDKN1B,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,KLF5,NRG1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,CNPY3,SPRY2,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,MPP1,FURIN,PARP4,LRRC1,GPLD1,NUCB1,AMMECR1,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,DENND2D,TMC1,SH3KBP1,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,TSPAN6,IMPAD1,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,POF1B,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,CXXC4,ARHGEF19,NEIL1,UEVLD,ADIPOR1,RAP1GAP,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,KCNN4,RFX5,NCEH1,LRIF1,GYLTL1B,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,NFKBIA,RHOBTB2,ALPK3,EGFL7,PITPNA,YOD1,PROM2,SLC25A24,PSME2,MORC4,TDRKH,ARHGEF16,SS18,SETDB2,FRYL,ZDHHC12,GOT1,RPN2,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,REEP4,LIFR,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,IL17RB,IRF2BPL,MDM1,MLPH,KIAA0319,IQGAP3,SUN2,RAB3B,ASPM,GCLC,MBNL3,LRRC66,OGDHL,DHRS2,HNRNPH2,OTUB2,L1CAM,SNPH |
| 3.877e-04 | -7.86 | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | 195 | 35 | 17758 | 1761 |
TXN,NFKBIE,NQO1,S100A11,CD63,ARHGEF11,DCAF7,FTH1,MGST2,DSE,M6PR,ATP6V0B,C7orf49,SLC16A6,PLCG2,CST3,DAPK1,TIAM1,SYK,NAGA,LAMP2,GCA,RAPGEF2,SLC11A2,ATP1B1,IDH1,CD83,KLHL2,GDE1,CORO1C,PNPLA6,RAB11FIP1,MDH1,PLIN3,ZMIZ1 |
| 3.877e-04 | -7.86 | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | MSigDB lists | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 195 | 35 | 17758 | 1761 |
MYL9,CTHRC1,PCOLCE,ENO2,SERPINE2,IL15,SDC4,SDC1,FBLN1,CTGF,CYR61,CALD1,TNFRSF12A,IGFBP2,SGCB,FBLN5,COL6A2,PLAUR,SAT1,COL7A1,LOXL2,SNTB1,COL12A1,DPYSL3,FAS,FUCA1,TIMP3,SCG2,PLOD2,MATN2,BMP1,ITGAV,GEM,PLOD3,COL16A1 |
| 3.877e-04 | -7.86 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 195 | 35 | 17758 | 1761 |
CASP3,TXN,PARP12,ST14,ERI2,CYB561,IL18,HMGN3,TGFBR1,B4GALT4,PHLDA1,EPCAM,IGSF9,FOSB,TUBG1,WWP1,MDFIC,FAH,METAP2,PLSCR1,CORO2A,MBNL3,PRKRA,ALCAM,CMTM7,GABARAPL1,CD83,SCRN2,PTPRJ,SWAP70,UAP1,AXL,LRIG1,MATN2,PRDM5 |
| 3.879e-04 | -7.85 | V$FOXO4_01 | MSigDB lists | V$FOXO4_01 | 225 | 39 | 17758 | 1761 |
LZTFL1,FRMD4A,CHCHD7,THRA,ETV5,FAM134A,CACNA2D2,DHRS3,ZNF385B,ZFYVE9,MECOM,NEO1,HDAC9,FOXP2,SESN3,ST5,CYR61,IL6ST,LMO4,VASN,TSPAN13,PDE4D,CITED2,PLCB2,ETV4,MAP3K3,TGIF1,KIF20A,NR3C1,RGAG1,LRRC1,LDB2,H2AFV,NFIB,KLF12,SLC4A4,NRG1,C1orf43,MAFF |
| 3.883e-04 | -7.85 | VALK_AML_CLUSTER_11 | MSigDB lists | VALK_AML_CLUSTER_11 | 35 | 11 | 17758 | 1761 |
GAS2L1,ALDH2,H1F0,KCNN4,DPYSL2,ITGA6,DAPK1,EGFL7,MDFIC,KLF9,LHFPL2 |
| 3.886e-04 | -7.85 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | MSigDB lists | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | 20 | 8 | 17758 | 1761 |
HLA-B,SEC23A,HLA-F,TAP1,ERAP1,PDIA3,HLA-C,HLA-A |
| 3.886e-04 | -7.85 | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | 20 | 8 | 17758 | 1761 |
ADD3,BMP7,FRAS1,ETV5,UACA,LOXL2,SPRY2,SOCS3 |
| 3.913e-04 | -7.85 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | 173 | 32 | 17758 | 1761 |
BIN1,MAN2B2,SIGIRR,GALNT12,TSC22D3,UBASH3B,EPHA4,HABP4,SNN,H1FX,TMCC3,FAM111A,LLGL2,DUSP10,TMEM9,S100A6,SUSD3,FBXL16,CASP9,DIAPH2,STMN3,NPC2,LDB2,RNPEP,TP53INP2,SFXN5,GABARAPL1,IRS2,PELI2,PIEZO1,TOB1,KLF7 |
| 3.914e-04 | -7.85 | human chr11p11.2 | chromosome location | human chr11p11.2 | 62 | 13 | 26250 | 1887 |
MDK,DDB2,PTPRJ,CD82,LRP4,TSPAN18,MADD,GYLTL1B,SLC35C1,CRY2,SYT13,TP53I11,MAPK8IP1 |
| 3.931e-04 | -7.84 | GRADE_COLON_AND_RECTAL_CANCER_DN | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_DN | 96 | 21 | 17758 | 1761 |
NR3C1,GNPDA1,GGA1,DAP,SERTAD4,CACNA2D2,OSGIN2,COL4A5,LDB2,ADAMTSL4,GNA11,HMGXB4,PARM1,B3GALNT1,LYPD3,MITF,TOX2,PLD1,FHL1,UNC5B,TLN2 |
| 3.957e-04 | -7.83 | REACTOME_SEMAPHORIN_INTERACTIONS | MSigDB lists | REACTOME_SEMAPHORIN_INTERACTIONS | 64 | 16 | 17758 | 1761 |
MYL9,DPYSL5,RHOA,ARHGEF11,ERBB2,PLXNA1,CDK5R1,DPYSL3,ARHGAP35,SEMA4D,LIMK1,DPYSL2,MYH14,SEMA3A,MYL12B,FARP2 |
| 3.975e-04 | -7.83 | reproductive system development | biological process | GO:0061458 | 404 | 63 | 16441 | 1675 |
COL9A3,NKX3-1,GRHL2,SERPINE2,CDKN1C,LGR4,EPAS1,ST14,CENPI,SOX9,TGFBR1,BCL2L1,SDC1,MERTK,PDGFB,SIX4,SGPL1,CCND1,E2F7,DAZAP1,IGF1R,ITGB8,LRRC6,PTEN,CYR61,GATA2,CST3,TOX2,DLG1,BAX,PLK4,TIPARP,MDFI,REC8,SIRT1,HES1,AKT1,FZD4,ASPM,TFAP2C,CCNF,FNDC3A,IDH1,PRDX4,SOCS3,PITX2,HS6ST1,NCOA3,FGFR2,HOXA9,AXL,CTSV,SPINT2,ARRB1,HOXB13,FZD5,OSR1,SOX8,E2F8,GAB1,AHR,RARG,EGLN1 |
| 3.977e-04 | -7.83 | TyrKc | smart domains | SM00219 | 88 | 21 | 9131 | 997 |
EPHA4,RET,ERBB2,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,EPHA10,IGF1R,JAK1,FGFR2,AXL,PTK7,RYK,MAP3K9,EPHB4,ERBB3,JAK3,SYK |
| 3.983e-04 | -7.83 | RADAEVA_RESPONSE_TO_IFNA1_UP | MSigDB lists | RADAEVA_RESPONSE_TO_IFNA1_UP | 52 | 14 | 17758 | 1761 |
MX1,CASP3,PLSCR1,IFITM3,HLA-E,BAX,CDKN1B,PRKCQ,IRF7,PSME1,IFIT1,HLA-C,IFI6,LGALS3BP |
| 4.000e-04 | -7.82 | BURTON_ADIPOGENESIS_8 | MSigDB lists | BURTON_ADIPOGENESIS_8 | 83 | 19 | 17758 | 1761 |
CD99,LAMP2,ANXA3,PRSS23,ASAH1,COL4A5,PRDX4,MAPKAPK2,TAPBP,TIMP3,TSPAN6,BAX,FXYD5,CTSA,SERPINB6,ITGAV,NCAM1,F2R,WBP5 |
| 4.000e-04 | -7.82 | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MSigDB lists | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | 83 | 19 | 17758 | 1761 |
MBP,MRC2,PINK1,CDKN1C,PLAUR,PLXNA1,SNN,PDGFB,PHLDA1,DDR1,GNA11,LMNA,PRX,SNTA1,MITF,TRIOBP,RAB11FIP1,EPHB4,PIK3CD |
| 4.039e-04 | -7.81 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 188 | 34 | 17758 | 1761 |
LASP1,SERPINE2,RASA2,NDC80,ERI2,PDCL,KIF23,CCNB1,STIL,LBR,IER3,ZFP36,RANBP1,SORL1,ATP8B1,AHCY,PTPRE,PPP6R1,METAP2,HES1,ALDH2,MBP,MMD,SNTB2,SAT1,ASB13,KDM4D,FOXD2,FUCA1,GNAS,PIK3C2B,STK39,GEM,ACOT7 |
| 4.039e-04 | -7.81 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | 188 | 34 | 17758 | 1761 |
TNRC6C,ADD1,ST14,GALNT12,ARL4C,NDRG2,TEX2,TRMT2B,GRK6,ETS1,BMP2K,PDIA4,DTX3L,RCN1,SRR,FAM102A,F2R,TPCN1,RASGRP1,PHF20L1,PTPN9,USP18,MYBL2,SPATA13,HMG20B,UAP1,RBL1,LIMK1,DCK,PRPS2,TRIOBP,PPM1H,NCAPG2,ESPL1 |
| 4.075e-04 | -7.81 | cellular macromolecule localization | biological process | GO:0070727 | 1151 | 152 | 16441 | 1675 |
SUN1,LAMP1,EXPH5,UGT8,TAP1,F11R,MPP5,SYTL4,HDAC6,ERP29,ZFYVE16,RAB15,AP1M2,DLG1,SNX16,SUN3,RAB20,CTTN,TLN2,PACSIN1,TRAM1,MYRIP,PLK1,KCNIP3,CENPA,EZR,ARFRP1,KIF13A,ICMT,CDK1,ARF4,OPTN,DNM1L,WIPI1,GNPTAB,ARF6,RRAGD,NFKBIE,GGA1,PEX6,SOX9,ETV5,RAB23,RAB6A,CNTNAP2,LMNA,ATG4A,MESDC2,SNX18,RPL39,KIF13B,EXOC8,SORL1,PIKFYVE,WNT3A,SYTL3,NUP85,RIMS2,MDFI,KDELR1,TRAK2,PMPCB,STRADB,NUBP1,STX3,AP1AR,SCARB2,TIMM8A,TMEM30A,NFKBIA,SH3BP4,FAM83D,ZDHHC7,AURKA,CTSA,LTBP2,ATP1B3,JAK3,TOB1,EHD1,ARMCX3,THRA,TP53,PKP2,EMP2,STIL,BCAP31,SYTL2,APPBP2,ZFYVE9,TTC21B,ACAP2,CDH1,ZDHHC12,REEP1,ZDHHC23,BCL6,RPN2,IFIT1,RAB27B,DLG3,LMAN1,SNX10,F2R,DVL2,CHP1,ATG4D,SEC23A,SEC61B,AKT1,PTPRU,SYNE2,RAB38,PYGO1,ATP1B1,DAG1,ATP10D,DDOST,PEX2,PACSIN2,PINK1,CD63,TSPAN15,FRMD6,LRP4,PSMD10,PDIA3,AIP,VPS26A,SIX4,ZDHHC21,RNF128,MLPH,ADORA1,BMP7,BAX,PLEKHF1,SYK,MYO5A,HES1,SUN2,RAB3B,FBLN5,CRB3,RAPGEF2,PIK3R1,PRICKLE1,BBS2,CNTNAP1,RPL12,SPCS3,WDR45B |
| 4.076e-04 | -7.81 | ERMFAMILY | prints domains | PR00661 | 16 | 7 | 4759 | 462 |
EPB41L5,EZR,EPB41L4B,NF2,EPB41L4A,MYLIP,FARP2 |
| 4.080e-04 | -7.80 | breast-other-papilloma | COSMIC cancer mutations | breast-other-papilloma | 30 | 10 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 4.081e-04 | -7.80 | mesenchymal cell differentiation | biological process | GO:0048762 | 134 | 27 | 16441 | 1675 |
EPB41L5,SEMA6B,HES1,S100A4,RET,AMER1,SOX9,TGFBR1,LOXL2,FAM101B,EFNB1,FGF19,EDNRA,PITX2,FGFR2,SEMA4D,CORO1C,BMP7,FAM83D,ADAM15,TWIST1,NRG1,SEMA3G,OSR1,SOX8,SEMA3A,SEMA3B |
| 4.082e-04 | -7.80 | ITPR1 (inositol 1,4,5-trisphosphate receptor, type 1) | protein interactions | 3708 | 43 | 13 | 16036 | 1726 |
BANK1,RHOA,AKT1,CABP1,AMFR,CALM1,PRKG1,TRPC1,ITPR3,CCNB1,PRKACA,CA8,CDK1 |
| 4.099e-04 | -7.80 | negative regulation of immune system process | biological process | GO:0002683 | 365 | 58 | 16441 | 1675 |
GAS2L1,CASP3,LGALS3,LGR4,NLRX1,TSC22D3,INPP5D,HLA-E,UBASH3B,SOX9,TAP1,ERBB2,IL27RA,CD274,PKN1,MERTK,HLA-A,NOV,ADORA1,PIK3AP1,GATA2,TSPAN6,IL31RA,BCL6,DLG1,DUSP10,TMBIM6,DAB2IP,IFIT1,C10orf54,SOCS5,HES1,CD55,PSMB4,ITCH,MICB,PIK3R1,PTGER4,PDE5A,EZR,ERBB2IP,ABR,FAS,HLA-B,BANK1,PTPRJ,HOXA9,AXL,TRAF3IP1,NFKBIA,NMI,INPP4B,NOD2,NLRC5,GPER1,NDFIP1,F2RL1,JAK3 |
| 4.099e-04 | -7.80 | regulation of neuron projection development | biological process | GO:0010975 | 365 | 58 | 16441 | 1675 |
GRN,SEMA6B,FOXO6,SERPINE2,SSH1,CIT,LRP4,RET,EPHA4,PLXNA1,CAMK1D,CRABP2,NCS1,ITGA3,PTEN,DPYSL2,MEGF8,KIF13B,BMP7,KIAA0319,TNFRSF12A,DAB2IP,CTTN,SEMA3G,PACSIN1,WNT3A,TIAM1,RIMS2,CCDC88A,SEMA3B,SSH3,RHOA,AKT1,RAPGEF2,CDC20,GRIN1,KLK6,CDK5R1,ARHGAP35,DPYSL3,PTPRF,GPRC5B,SEMA4D,BHLHB9,PTK7,LIMK1,TMEM30A,PLK2,SIPA1L1,NRG1,EFNA5,ARF6,ITPKA,ARSB,SEMA3A,COBL,LZTS1,L1CAM |
| 4.115e-04 | -7.80 | ACTIN_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | ACTIN_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 103 | 22 | 17758 | 1761 |
WASF3,PACSIN2,SORBS1,RHOA,NF2,SSH1,EZR,TESK2,ARHGDIB,MRAS,BCAR1,RASA1,ARHGEF10L,RND3,LIMK1,DLG1,PRKG1,FGD6,ARF6,SHROOM2,CCDC88A,FGD1 |
| 4.131e-04 | -7.79 | TCGA_GLIOBLASTOMA_MUTATED | MSigDB lists | TCGA_GLIOBLASTOMA_MUTATED | 8 | 5 | 17758 | 1761 |
ERBB2,PTEN,PIK3R1,PIK3CA,TP53 |
| 4.146e-04 | -7.79 | dysplasia-carcinoma_in_situ | COSMIC cancer mutations | dysplasia-carcinoma_in_situ | 25 | 9 | 17775 | 1757 |
GNAS,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 4.148e-04 | -7.79 | regulation of protein dephosphorylation | biological process | GO:0035304 | 148 | 29 | 16441 | 1675 |
CAMSAP3,SPRED1,PINK1,LMTK3,PPP4R4,PPP1R2,NUAK1,CALM1,CALM3,CDCA2,PKMYT1,TIPRL,SH2D4A,PPP2R3A,SYTL2,GPLD1,CALM2,SWAP70,ADORA1,PPP2R5A,NPNT,SEMA4D,CRY2,SLC39A10,DLG3,PPP2R2D,PPP6R1,ARFGEF3,CHP1 |
| 4.168e-04 | -7.78 | negative regulation of intracellular protein transport | biological process | GO:0090317 | 94 | 21 | 16441 | 1675 |
TXN,ERLEC1,NFKBIE,THRA,LITAF,RAB23,PSMD10,BARD1,APC2,NOV,SP100,BMP7,CABP1,NFKBIA,UBE2J1,DAB2IP,MDFIC,YOD1,PKIA,MDFI,CHP1 |
| 4.188e-04 | -7.78 | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 30 | 10 | 17758 | 1761 |
PITX2,CD55,CTGF,MICB,HLA-E,TFAP2A,MDFIC,HLA-C,SEPP1,CTH |
| 4.188e-04 | -7.78 | TING_SILENCED_BY_DICER | MSigDB lists | TING_SILENCED_BY_DICER | 30 | 10 | 17758 | 1761 |
SERPINA1,SLC4A4,CYR61,DHRS2,SERTAD4,PELI2,APOBEC3G,HOXB2,CPEB2,RASGRP1 |
| 4.197e-04 | -7.78 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | 181 | 33 | 17758 | 1761 |
GAS2L1,SUN1,CCDC109B,MORC4,CALM3,AIP,CALM2,RPS6KA2,GNB5,ARTN,LYPD3,FABP6,PASK,WWP1,EPHB4,SMYD5,MAST4,SEMA3B,FBLN5,MPP1,CALM1,STMN3,PRKRA,STK17B,ATP1A1,TJP3,INPP4B,NR4A2,HMGA1,RGS14,HSPB1,TBC1D4,PKIA |
| 4.219e-04 | -7.77 | WALLACE_PROSTATE_CANCER_RACE_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_UP | 272 | 45 | 17758 | 1761 |
CCDC109B,PARP12,KIAA1462,IL15,CKAP2,HLA-E,HLA-F,TMX4,ARL4C,TAP1,SELL,HERC5,BTN3A1,HERC6,CCND1,TYMP,CTSC,IFIT1,HLA-C,MYBL1,APOBEC3G,RASGRP1,LAMP3,MX1,IFITM3,SEPT6,AMFR,BTN3A2,RUNX3,IFIT3,STK17B,EDNRA,CD83,OPTN,IRS2,HLA-B,GPRC5B,PDLIM3,ETS2,NAT1,SECTM1,NR4A3,ERAP1,NR4A2,IFI6 |
| 4.228e-04 | -7.77 | positive regulation of cell proliferation | biological process | GO:0008284 | 800 | 111 | 16441 | 1675 |
FOXM1,IL15,CNOT8,COL18A1,ERBB2,IL18,OSR2,BCL2L1,CD274,CCNB1,PRKACA,PDGFB,EMP2,TNFSF9,LTBP3,CCND1,PDGFA,EPCAM,CTGF,IL6ST,KIF14,IL31RA,BCL6,DLG1,AKR1B1,CDH3,CDKN1B,RTKN2,TWIST1,PDE4D,NOTCH3,SLC39A10,F2R,S100A13,SIRT1,CD55,RIPK2,AKT1,CDC20,PRKCQ,ICMT,CD40,SLC25A5,FZD7,OPTN,IRS2,PGF,HPSE,NOD2,HDAC1,NRG1,SP6,TRAF5,LIFR,CAPN1,GRN,SCN5A,CTHRC1,RUNX2,NKX3-1,ADGRG1,HLA-E,SOX9,ETV5,SLC25A27,TGFBR1,ETS1,FBLN1,EFNB1,FGF19,NRP2,HLA-A,C9orf69,TNS3,IGF1R,CYR61,PTEN,CST3,IGFBP2,MYDGF,CNOT6L,WNT3A,IQGAP3,SYK,S100A6,HES1,PDGFC,TGIF1,ASPM,NR4A1,EIF5A2,UBE2A,EPHA1,STX3,NUDT16,FGFR2,SCG2,ACVRL1,CSF1,CDCA7L,TBX18,NR4A3,EGFL7,ITGAV,GPER1,SOX8,ICOSLG,OSR1,ZMIZ1,JAK3,RARG |
| 4.259e-04 | -7.76 | calcium ion binding | molecular function | GO:0005509 | 677 | 96 | 16491 | 1673 |
PLA2G4A,MYL9,LTBP1,SLC25A24,REPS2,S100A11,SLC25A13,IQGAP1,RET,SYTL4,DNER,REPS1,LTBP3,NCS1,SYTL2,EPDR1,PLS3,CALM2,RCN1,CDH1,STIM1,NPNT,CABP1,SRR,CDH3,NOTCH3,S100A13,RASGRP1,CHP1,SULF2,GCA,KCNIP3,MCTP1,CELSR2,S100A4,MCFD2,MYL12A,DAG1,NIN,PLCH1,ENPP1,DUOX1,PLCG1,MMP17,GNPTAB,NKD1,BMP1,EFCAB14,ANXA9,SYT13,MYL12B,CAPN1,ANXA3,CDH22,CALB2,LRP4,CALM3,EFHD2,NUCB2,S100A2,FBLN1,HPCAL4,PRRG4,PPP2R3A,MEGF8,PLCB2,DGKG,SYTL3,S100A6,MYO5A,PCDH1,FBLN5,PLSCR1,TBC1D8B,RAPGEF2,CALM1,GRIN1,AIF1L,CDK5R1,RASGRP2,MMP15,GALNT3,NUCB1,SWAP70,FAT4,SYT7,CGREF1,MATN2,S100A5,PCDH19,EGFL7,LTBP2,MELK,ESYT2,TLL2,EHD1 |
| 4.299e-04 | -7.75 | PLTP (phospholipid transfer protein) | protein interactions | 5360 | 28 | 10 | 16036 | 1726 |
EPB41L5,UGT8,PLAUR,IMPAD1,HLA-F,PCYOX1,GLB1L2,GALNT7,ABCA1,FAM69A |
| 4.304e-04 | -7.75 | Role of LAT2/NTAL/LAB on calcium mobilization | REACTOME pathways | R-HSA-2730905 | 104 | 23 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,PDGFA,IRS2,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,SYK,GAB1 |
| 4.392e-04 | -7.73 | V$EGR1_01 | MSigDB lists | V$EGR1_01 | 257 | 43 | 17758 | 1761 |
SPRED1,CMAS,PCOLCE,CDK17,PACSIN2,MRC2,CEP70,UBASH3B,MORF4L2,PDGFB,PRKACA,SPTB,SH3KBP1,SLC9A7,IRF2BPL,CDKN2C,FOXP2,APLP2,ITGB8,RALGPS2,SH3BP1,WDR44,KLF3,CNNM4,TNFRSF12A,CNOT6L,RASGEF1A,SMYD5,C12orf75,ETV4,C9orf72,DVL2,SOCS5,RHOA,GRIN1,TFAP2C,MAN2A2,CORO1C,PITPNA,HMGA1,PLOD3,SLC25A38,NRGN |
| 4.409e-04 | -7.73 | TMEM255A (transmembrane protein 255A) | protein interactions | 55026 | 11 | 6 | 16036 | 1726 |
WWP1,GCA,KCTD2,UBASH3B,ITCH,WWP2 |
| 4.411e-04 | -7.73 | small GTPase binding | molecular function | GO:0031267 | 244 | 42 | 16491 | 1673 |
EXPH5,PIFO,RALBP1,RUSC2,IQGAP1,EPS8,SYTL4,NCKAP1,PKN1,ARHGEF16,SYTL2,RABGGTA,ACAP2,MLPH,LLGL2,RANBP1,EXOC8,SORL1,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,STRADB,DIAPH2,RANBP9,OPTN,RAB11FIP2,CORO1C,SH3BP4,TRIOBP,RAB11FIP1,FGD6,ITPKA,RAP1GAP,ABCA1,DOCK9,EHD1,FGD1 |
| 4.438e-04 | -7.72 | mesenchymal cell development | biological process | GO:0014031 | 121 | 25 | 16441 | 1675 |
EPB41L5,SEMA6B,HES1,S100A4,RET,SOX9,TGFBR1,LOXL2,FAM101B,EFNB1,FGF19,EDNRA,PITX2,FGFR2,SEMA4D,CORO1C,BMP7,FAM83D,ADAM15,TWIST1,NRG1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 4.455e-04 | -7.72 | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | 41 | 12 | 17758 | 1761 |
CDKN2C,TRIM8,CENPA,DOK4,S100A4,AOX1,CBX6,KIF23,ARRB1,NDE1,MINPP1,ABCG1 |
| 4.465e-04 | -7.71 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_UP | 189 | 34 | 17758 | 1761 |
PTTG1,OSGIN2,C5orf30,HMGN3,CACNB4,B4GALNT1,CDKN2C,TFAP4,PDGFA,TRIM21,SGK1,CTTN,PIM1,BTBD3,TIAM1,DVL2,FAH,PPIF,ARAP2,PTGER4,CD40,IFIT3,CASP4,PRX,NFIX,ENDOD1,HLA-B,ACADSB,PVRL2,CSF1,NAT1,STK39,PLOD3,IFIH1 |
| 4.465e-04 | -7.71 | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 34 | 17758 | 1761 |
MYL9,LASP1,CPT2,RGS20,NENF,TEX2,FAM198B,NTAN1,ARHGEF40,CENPN,SIRPA,APLP2,ITGA3,CTSC,TNFRSF12A,TACSTD2,MYO5A,CKS2,LOC81691,CDA,ACO1,PRKAR2B,KIF11,IDH1,STX3,CD83,FUCA1,SWAP70,ANKRD6,WIPI1,CSF1,HSPB1,ACOT7,CYBRD1 |
| 4.479e-04 | -7.71 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 219 | 38 | 17758 | 1761 |
EXPH5,RMND5A,ENO2,FAM169A,PPP1R2,SLC25A13,DCAF7,TESK2,DHX8,IL27RA,PRKACA,STIL,PARM1,B3GALNT1,BTG3,RGS3,DLG1,PDE4D,DLG3,PTPRE,IGSF3,LAMP3,NFE2L3,PLSCR1,HSPA12A,RUNX3,RNF19B,PDLIM3,KCNK1,NAT1,ATP7B,NR4A3,ABCB1,SFMBT1,IFI6,ZBTB33,NXT2,NR2C2 |
| 4.497e-04 | -7.71 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 312 | 50 | 17758 | 1761 |
COL9A3,PAPSS2,ENO2,DAP,TMX4,MTL5,CACNA2D2,C5orf30,MORC4,PKP2,CRABP2,PSIP1,APLP2,IGF1R,METTL7A,IL6ST,ALDH1A3,AIM1,OPN3,CDKN1B,LIMCH1,FAR2,S100A13,MPHOSPH9,PPIF,MICB,C3orf52,AK4,PRKAR2B,RAB38,ASB13,IDH1,ALCAM,SPTLC2,CYB5A,OPTN,GALNT3,PLCH1,SWAP70,GPRC5B,FGFR2,DBI,PGRMC1,TLE1,STK39,ANXA9,MAP3K5,PER3,TRAF5,ACOT7 |
| 4.534e-04 | -7.70 | TTTGCAC,MIR-19A,MIR-19B | MSigDB lists | TTTGCAC,MIR-19A,MIR-19B | 499 | 73 | 17758 | 1761 |
CAST,ARFGEF1,C5orf30,TESK2,TGOLN2,GRK6,SDC1,FAM46C,ZFYVE9,WEE1,CTGF,WDR44,ENPP5,ANKRD12,ACSL4,TLN2,SMARCA2,TNIP1,DAG1,ABR,SOCS3,HLF,MID1IP1,CDK19,STK38,SLC9A6,FAM114A1,LRIG1,CAB39,FAM195A,E2F8,CBX7,ABCA1,RUNX2,CPEB4,ITGA6,MIER3,TTYH3,ANO1,SLC9A2,NRP2,PARM1,SGK1,TNFRSF12A,MDFIC,MYLIP,PPP6R1,MPHOSPH9,CCDC88A,IGSF3,TRAK2,SOCS5,DPYSL5,ACBD5,TGIF1,ELK3,SYBU,PPARA,UBE2A,PDE5A,RUNX3,FNDC3A,CSNK1G1,ITPR1,RAP2C,CLIP4,SFMBT1,PGM2L1,ZDHHC7,NR4A2,LRRK1,NIPA1,SNPH |
| 4.544e-04 | -7.70 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 719 | 99 | 17758 | 1761 |
PLA2G4A,MFSD3,ARMCX3,REPS2,IL15,CUL4B,TAP1,ARFGEF1,C5orf30,CTGF,SP100,TRANK1,NPNT,RPN2,TMEM64,ERAP2,LAMP3,MX1,SPEF2,RIPK2,OSTM1,SAT1,LHFPL2,CASP4,NIN,AHRR,C19orf66,P4HA2,LIMK1,ADAMTS14,SERPINI1,DDX58,GCLM,MRPL44,CDK17,PARP12,MACC1,POC1B,HABP4,ETV5,SLC25A27,PBX3,HERC5,SAMD9,SLC1A3,BEX2,MECOM,ZDHHC21,CTSC,SPIN4,FLRT3,LYPD6,CALD1,ALG13,GTF2F2,DRAM1,SGK1,GAD1,NDUFA12,CCDC88A,PARP9,PDGFC,PHF20L1,ARAP2,PLSCR1,RGMB,SALL4,DEPDC4,NR4A1,OGDHL,FBXO9,PCTP,GLT8D2,STEAP1,ENDOD1,PTPRF,AP1AR,SLC4A4,UAP1,PLOD2,DHRS2,CGREF1,TMC5,NMI,MATN2,P4HA3,NETO2,NR4A3,PGM2L1,CSTF2,ERAP1,YOD1,PLD1,GEM,IFIH1,APOL2,IFI6,RNF146,EGLN1 |
| 4.550e-04 | -7.70 | VEGFR1 specific signals | Pathway Interaction DB | vegfr1_pathway | 29 | 12 | 2227 | 331 |
PGF,CALM2,PLCG1,AKT1,CALM1,PIK3R1,PIK3CA,CALM3,PRKACA,GAB1,RASA1,NRP2 |
| 4.551e-04 | -7.70 | cellular response to peptide hormone stimulus | biological process | GO:0071375 | 454 | 69 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,PSME2,NRG2,ERBB2,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PIK3CA,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,AKT1,PRKAR2B,POR,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,CAB39,EIF4EBP2,SPTBN5,NRG1,GAB1,RRAGD,PRKAA2,RASA2,PSMD10,CALM3,FGF19,HDAC9,IGF1R,ERBB3,NCAM1,MYO5A,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,NR4A3,NR4A2,GRIN2D,GPER1,TBC1D4,JAK3,CPEB2 |
| 4.559e-04 | -7.69 | acute_myeloid_leukaemia | COSMIC cancer mutations | acute_myeloid_leukaemia | 10922 | 1144 | 17775 | 1757 |
AK7,SLC25A13,HEXB,RET,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,TMOD2,ITPKA,SCN5A,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,MARCH8,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,HPS3,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,TMEM173,ADAMTS16,DOCK9,PTTG1,GRK6,MGST2,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,ZNF365,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,DNAJB14,ZNF618,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,PNPLA6,ISOC1,MAPK12,CTHRC1,ESRP1,SDC4,CTSZ,SLC25A43,FUT2,ITGB8,MGAT4A,FAM20B,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,CPNE2,RPS6KA2,NPNT,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,THRB,CELSR2,STAU2,NFE2L1,CR2,DZIP1L,TRIM9,KLF12,ARRDC1,KLF11,MYL12B,RRAGD,PARP12,HJURP,DNAJB2,FXYD3,RASA2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,EFNA5,IRF7,ZMAT1,BIN1,CDH22,CPEB4,HAL,ERI2,HMGN3,LBR,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,CD109,FOXP2,ALPP,GTF2F2,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,PSME1,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,HYLS1,MARCH2,METAP2,SPATA18,KIF13A,LDB2,POR,PRIM1,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,TBC1D1,TNFRSF19,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,NPC2,ATP8B3,ANTXR1,NFIB,PLEKHH2,TJP3,FAAH,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,CCDC110,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,SULT2B1,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ITPR3,ASB13,ALCAM,ATP10D,AMZ2,DDOST,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,HLA-A,SLC25A36,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,ESPL1,MELK,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,RAB15,SIPA1L2,ARHGEF37,SIVA1,ANKFN1,TRPC1,MYRIP,BTBD3,NLRP4,CENPA,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,MDFI,SNX7,TPGS2,PODXL2,PDE5A,HEATR5A,STEAP1,MFSD7,RANBP9,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,LMO7,CCNE2,NCKAP5,LZTFL1,PDIA5,COL18A1,IL27RA,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,FANCE,ARHGAP35,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,PGM1,SYBU,TTC7A,LEPR,ARHGAP24,ENDOD1,SWAP70,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,ACACB,IL15RA,ADD1,AASS,MRPS15,MMADHC,CACNA2D2,NRG2,DHX8,IL18,SYTL4,BARD1,CA8,WEE1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,PIK3CD,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,E2F8,GAB1,FAM169A,ALDH6A1,NFKBIE,MERTK,RAVER2,GNS,FAM189A1,NEK2,NCAM1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,ITPR1,AURKA,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,XDH,ARHGAP11A,CCDC109B,PAPSS2,GRHL2,GALNT12,ACTR8,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,ENPP4,SSH3,FZD4,SYNE2,CDCA2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,ETS1,GSTP1,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,ANKS1B,ALG13,CALD1,ECI2,WWP1,NPTXR,CRTAP,AMOTL2,LCA5,FMN1,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,CRISPLD2,PITX2,GALNT3,NR1D2,CENPE,CYBRD1,DCBLD1,MYL9,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,CNTRL,SHC3,ELF5,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,ZCCHC24,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,ALDH3A2,C9orf9,ABCC1,CHSY3,CYP26B1,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,EFR3A,PLCG2,SCN2A,MINPP1,DVL2,GM2A,CTH,SIRT1,CPD,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,MACC1,RUSC2,DAP,SELL,GABRG2,NKRF,SIRPA,SLC9A2,CCDC92,ABCD1,BUB1,KLF9,TLE6,IGDCC4,FAH,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,BCAR1,MAPK8IP1,PRDX4,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NMI,NETO2,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,LOC81691,ORAI2,TMEM68,KIFC2,SNTB2,PBK,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,CCNF,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,PLK2,GNPTAB,PTER,NKD1,DHTKD1,UNC5B,TANC2,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,B3GNT7,PMPCB,ZNF84,MMD,MFI2,TBC1D8B,AMER1,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,ARMCX3,NLRX1,TRIP10,RPS6KA1,CAST,IQGAP1,RNF182,AIFM2,TMPRSS4,MNS1,ZNF75D,FAM46A,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,NIN,CMTM7,PRDM11,EPHA10,JAK1,NRG1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SIX4,TMCC3,FAM111A,PHF7,PTEN,ATP8B1,SLC44A2,TAGLN2,CNOT6L,SPRY2,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,CCDC69,CSTF2,SLC25A38,ARSB,NCAPG2,JARID2,ESYT2,EXPH5,CASP3,LTBP1,CPT2,CAMKK1,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,ANKRD12,POF1B,SUN3,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,RNF113A,GNAS,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,SLC25A24,FAM92A1,IL15,PSME2,TDRKH,LRRC45,SLC25A48,SETDB2,FRYL,RPN2,PDIA6,FRS3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,BFSP1,VSIG10,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IRF2BPL,IL17RB,MDM1,MLPH,KIAA0319,IQGAP3,SUN2,SYPL1,ASPM,DEPDC4,GCLC,LRRC66,OGDHL,KLHL2,HLA-B,C2orf70,PRCP,OTUB2,GEM |
| 4.559e-04 | -7.69 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | 10922 | 1144 | 17775 | 1757 |
AK7,SLC25A13,HEXB,RET,FAM46C,CMTM6,CARD10,LTBP3,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TFAP2C,PRKAR2B,ENPP1,PLCG1,ATP7B,FAM114A1,TRAF3IP1,TMOD2,ITPKA,SCN5A,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,MARCH8,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,HPS3,SFXN5,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,TMEM173,ADAMTS16,DOCK9,PTTG1,GRK6,MGST2,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,ZNF365,MYT1,SNX10,MX1,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,DNAJB14,ZNF618,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,PNPLA6,ISOC1,MAPK12,CTHRC1,ESRP1,SDC4,CTSZ,SLC25A43,FUT2,ITGB8,MGAT4A,FAM20B,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,CPNE2,RPS6KA2,NPNT,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,THRB,CELSR2,STAU2,NFE2L1,CR2,DZIP1L,TRIM9,KLF12,ARRDC1,KLF11,MYL12B,RRAGD,PARP12,HJURP,DNAJB2,FXYD3,RASA2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,EFNA5,IRF7,ZMAT1,BIN1,CDH22,CPEB4,HAL,ERI2,HMGN3,LBR,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,CD109,FOXP2,ALPP,GTF2F2,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,PSME1,NANS,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,HYLS1,MARCH2,METAP2,SPATA18,KIF13A,LDB2,POR,PRIM1,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,TBC1D1,TNFRSF19,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,PRKG1,ADCK2,TPST1,OSTF1,C8orf58,CACNA1D,SYTL3,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,ADCK3,NPC2,ATP8B3,ANTXR1,NFIB,PLEKHH2,TJP3,FAAH,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,KLK7,PER3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,DLGAP5,CCDC110,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,SULT2B1,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ITPR3,ASB13,ALCAM,ATP10D,AMZ2,DDOST,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,FBXO6,DNAH3,HLA-A,SLC25A36,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,FARP2,TGIF1,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,KIF11,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,ESPL1,MELK,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,RAB15,SIPA1L2,ARHGEF37,SIVA1,ANKFN1,TRPC1,MYRIP,BTBD3,NLRP4,CENPA,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,MDFI,SNX7,TPGS2,PODXL2,PDE5A,HEATR5A,STEAP1,MFSD7,RANBP9,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,LMO7,CCNE2,NCKAP5,LZTFL1,PDIA5,COL18A1,IL27RA,KCTD9,ZNF687,CYP4F11,KIF14,REEP1,EPB41L4B,ECE1,SEPHS1,PTPRU,GLO1,FANCE,ARHGAP35,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,PGM1,SYBU,TTC7A,LEPR,ARHGAP24,ENDOD1,SWAP70,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,ACACB,IL15RA,ADD1,AASS,MRPS15,MMADHC,CACNA2D2,NRG2,DHX8,IL18,SYTL4,BARD1,CA8,WEE1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,ALDH1A3,FUT1,TUBG1,PIK3CD,APOBEC3G,ERAP2,SMARCA2,SPEF2,TNIP1,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,E2F8,GAB1,FAM169A,ALDH6A1,NFKBIE,MERTK,RAVER2,GNS,FAM189A1,NEK2,NCAM1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,ITPR1,AURKA,FBXO27,NDE1,DRP2,ZNF502,SERPINB1,XDH,ARHGAP11A,CCDC109B,PAPSS2,GRHL2,GALNT12,ACTR8,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,ENPP4,SSH3,FZD4,SYNE2,CDCA2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,ETS1,GSTP1,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,ANKS1B,ALG13,CALD1,ECI2,WWP1,NPTXR,CRTAP,AMOTL2,LCA5,FMN1,RAPGEF2,EIF5A2,GRIN1,MYEOV,BLVRA,CRISPLD2,PITX2,GALNT3,NR1D2,CENPE,CYBRD1,DCBLD1,MYL9,TRIM2,FAM199X,PPM1J,CUL4B,EPHA4,FHDC1,TP53I11,HDAC6,CNTRL,SHC3,ELF5,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,CCDC38,ZNF462,MCTP1,EZR,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,RHEB,OPTN,DPYSL3,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,ZCCHC24,HLA-F,UBASH3B,ASAH1,CNTNAP2,B4GALT4,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,MDFIC,PLCB2,ALDH3A2,C9orf9,ABCC1,CHSY3,CYP26B1,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,ERBB2,CCDC68,SLC7A2,LPIN3,CYP26A1,RAD23A,EFR3A,PLCG2,SCN2A,MINPP1,DVL2,GM2A,CTH,SIRT1,CPD,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,ZNF701,MAN2B2,COL9A3,GOLIM4,MACC1,RUSC2,DAP,SELL,GABRG2,NKRF,SIRPA,SLC9A2,CCDC92,ABCD1,BUB1,KLF9,TLE6,IGDCC4,FAH,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,BCAR1,MAPK8IP1,PRDX4,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,NMI,NETO2,FAM117A,CLIP4,PPP2R3C,UBE2C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,LOC81691,ORAI2,TMEM68,KIFC2,SNTB2,PBK,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,CCNF,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,AHRR,PLK2,GNPTAB,PTER,NKD1,DHTKD1,UNC5B,TANC2,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,OPN3,SORL1,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,B3GNT7,PMPCB,ZNF84,MMD,MFI2,TBC1D8B,AMER1,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,FRMPD3,ARMCX3,NLRX1,TRIP10,RPS6KA1,CAST,IQGAP1,RNF182,AIFM2,TMPRSS4,MNS1,ZNF75D,FAM46A,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SP4,NIN,CMTM7,PRDM11,EPHA10,JAK1,NRG1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,ATP9A,ARL4C,CCNJL,APOBEC3H,SIX4,TMCC3,FAM111A,PHF7,PTEN,ATP8B1,SLC44A2,TAGLN2,CNOT6L,SPRY2,OSGIN1,NCOA2,RASGRF1,ARAP2,SHMT1,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,CCDC69,CSTF2,SLC25A38,ARSB,NCAPG2,JARID2,ESYT2,EXPH5,CASP3,LTBP1,CPT2,CAMKK1,CACNB4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,ANKRD12,POF1B,SUN3,RP2,MYH14,TECR,PTPRE,RASGRP1,ATL1,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,CXXC4,NEIL1,ADIPOR1,RAP1GAP,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,FXYD5,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,RNF113A,GNAS,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,NFKBIA,CDCA5,RHOBTB2,ALPK3,PITPNA,SLC25A24,FAM92A1,IL15,PSME2,TDRKH,LRRC45,SLC25A48,SETDB2,FRYL,RPN2,PDIA6,FRS3,MAP3K3,ZNF525,GCA,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,BFSP1,VSIG10,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IRF2BPL,IL17RB,MDM1,MLPH,KIAA0319,IQGAP3,SUN2,SYPL1,ASPM,DEPDC4,GCLC,LRRC66,OGDHL,KLHL2,HLA-B,C2orf70,PRCP,OTUB2,GEM |
| 4.559e-04 | -7.69 | GU_PDEF_TARGETS_UP | MSigDB lists | GU_PDEF_TARGETS_UP | 71 | 17 | 17758 | 1761 |
DOCK4,COL6A2,FZD4,ITGA6,COL4A5,SDC1,MAPKAPK2,PLCG1,ITGA3,CTGF,SERPINA1,COL13A1,COL6A1,HDAC1,SERPINI1,PIK3CD,COL16A1 |
| 4.559e-04 | -7.69 | V$LXR_Q3 | MSigDB lists | V$LXR_Q3 | 71 | 17 | 17758 | 1761 |
CCNI,SLC2A4,NUAK1,LYRM1,BLVRB,HPCAL4,NKAIN3,NFKBIA,MITF,SGK1,NRG1,ETV4,ABCA1,RARG,SPRY2,ABCG1,JARID2 |
| 4.559e-04 | -7.69 | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | MSigDB lists | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | 71 | 17 | 17758 | 1761 |
BMF,COL6A2,HAPLN3,LRRC66,COL7A1,DDR1,ADRBK2,LGALS3BP,SH2D4A,PTPRF,ANKS1B,CYR61,PTK7,BMP1,PIM1,F2R,L1CAM |
| 4.562e-04 | -7.69 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | 352 | 55 | 17758 | 1761 |
CD99,UGP2,ALDH6A1,HEBP1,ATP9A,PTTG1,PSMD10,INTS8,NUCB2,BARD1,CENPN,PSIP1,BCAP31,TOP2A,DPYSL2,FOSB,CD9,ECI2,AHCY,CITED2,PDIA6,APOBEC3G,CKS2,METAP2,HMMR,MRPS33,RHOA,ZWINT,MPP1,SH3BGRL,NUSAP1,GGH,GLO1,FOS,KIF11,CDK1,CYB5A,FRMD4B,PRDX4,PRIM1,ALDH5A1,PRPS2,LRIG1,TCEAL4,MDH1,HMGA1,FHL1,TBC1D4,LTA4H,HSPB1,CCNB2,TMEM14A,ISOC1,E2F8,MELK |
| 4.573e-04 | -7.69 | PI-3K cascade:FGFR4 | REACTOME pathways | R-HSA-5654720 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.573e-04 | -7.69 | PIP3 activates AKT signaling | REACTOME pathways | R-HSA-1257604 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,PDGFA,IRS2,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1 |
| 4.573e-04 | -7.69 | PI-3K cascade:FGFR2 | REACTOME pathways | R-HSA-5654695 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.573e-04 | -7.69 | PI3K events in ERBB2 signaling | REACTOME pathways | R-HSA-1963642 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.573e-04 | -7.69 | PI3K events in ERBB4 signaling | REACTOME pathways | R-HSA-1250342 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.573e-04 | -7.69 | PI-3K cascade:FGFR1 | REACTOME pathways | R-HSA-5654689 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.573e-04 | -7.69 | PI-3K cascade:FGFR3 | REACTOME pathways | R-HSA-5654710 | 98 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.576e-04 | -7.69 | Signaling by Leptin | REACTOME pathways | R-HSA-2586552 | 236 | 42 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,LEPR,PSMA4,RASA1,SOCS3,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 4.616e-04 | -7.68 | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | 491 | 72 | 17758 | 1761 |
GAS2L1,PAPSS2,GRK6,PJA2,PRKACA,ZFYVE16,SS18,TYMP,AP1M2,RPS6KA2,IQCE,IL6ST,TRPC1,MYH14,ECE1,DLG3,F2R,CDKN2D,TIAM1,SMAGP,SIRT1,SMARCA2,CBX6,ACO1,SLC35C1,RAD17,ICMT,SESN1,DAG1,EDNRA,ARHGAP35,SOCS3,CDK19,WFS1,LRRFIP2,FRMD4A,ZCCHC24,EPS8,GNE,ABCG2,ASAH1,C6orf106,RAB6A,SBF1,MERTK,SEPP1,TSPAN7,DNAJB9,CDK16,ADAM15,LIMCH1,SYK,CRTAP,KLK5,PIK3R1,MYBL2,FNDC3A,LEPR,RASA1,FAT4,COL13A1,CSF1,CGREF1,CCDC69,CDK18,STK39,HMGA1,MAP3K5,ESPL1,RARG,DEF6,ACOT7 |
| 4.623e-04 | -7.68 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | 160 | 30 | 17758 | 1761 |
HMMR,MX1,REC8,PARP12,IFITM3,PSME2,HLA-E,USP18,HLA-F,HERC5,IFIT3,HERC6,SBF1,STIL,LGALS3BP,HLA-A,HLA-B,TYMP,NCOA3,TAF1B,TRANK1,C19orf66,NMI,IRF7,IFIT1,HLA-C,OAS3,IFIH1,IFI6,CKS2 |
| 4.623e-04 | -7.68 | SMID_BREAST_CANCER_LUMINAL_B_UP | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_UP | 160 | 30 | 17758 | 1761 |
NUDT6,REPS2,HDAC11,RET,SYBU,MTL5,CACNA2D2,GDF15,ISYNA1,CRABP2,TRIM9,CCND1,ENPP1,MLPH,TJP3,ACADSB,FGFR2,IL6ST,FLRT3,NAT1,RAB11FIP1,WWP1,SERPINI1,ANXA9,ACOX2,CACNA1D,MYT1,PTGES,MCCC2,SEMA3B |
| 4.672e-04 | -7.67 | phospholipid translocation | biological process | GO:0045332 | 20 | 8 | 16441 | 1675 |
KCNN4,ATP8A1,ATP9A,TMEM30A,ATP8B1,ATP8B3,ABCA1,ATP10D |
| 4.696e-04 | -7.66 | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | 84 | 19 | 17758 | 1761 |
HMMR,CENPA,TXN,CDC20,MYBL2,KIF23,CCNB1,H2AFV,CDK1,PRDX4,CDKN2C,TOP2A,IDE,CDCA5,AURKA,CENPE,CCNB2,E2F8,MELK |
| 4.713e-04 | -7.66 | gland morphogenesis | biological process | GO:0022612 | 108 | 23 | 16441 | 1675 |
NKX3-1,RPS6KA1,SOX9,ERBB2,EZR,TFAP2C,SCRIB,PLXNA1,DAG1,NFIB,ELF3,NCOA3,IGF1R,TWSG1,FGFR2,CSF1,BMP7,HOXB13,SEMA3A,ETV4,SLC12A2,RARG,CAPN1 |
| 4.718e-04 | -7.66 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 197 | 35 | 17758 | 1761 |
GCLM,GOLIM4,IL15RA,LGALS3,IL15,CHCHD7,ASAH1,PBX3,KCTD12,NCKAP1,IL18R1,IER3,DAPK2,AIM1,MDFIC,OSTF1,TMEM37,F2R,SNX10,S100A13,S100A6,PQLC3,PLSCR1,LPGAT1,S100A4,LITAF,GGH,DOCK5,CASP4,ENPP1,ABCB1,SERPINB6,TMEM159,ACOT7,MAPK12 |
| 4.718e-04 | -7.66 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | 197 | 35 | 17758 | 1761 |
CASP3,GCLM,LGALS3,PTTG1,NDC80,IL27RA,HLA-A,M6PR,METTL7A,PAPSS1,PPP4R1,SRR,DAPK1,PDIA6,GM2A,LAMP2,DDB2,KIF20A,ASPM,CDC20,CASP9,C1GALT1C1,NUSAP1,FANCE,IDH1,PPP2R5A,PRCP,RAB11FIP1,AURKA,PIEZO1,ZMIZ1,ARPC2,CCNB2,SERPINB1,MELK |
| 4.718e-04 | -7.66 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 197 | 35 | 17758 | 1761 |
TXN,S100A11,PTTG1,EFHD2,FAM46C,MNS1,IL18R1,FGF19,HLA-A,DAPK2,WEE1,FOSB,AIM1,SORL1,MDFIC,TMEM37,PIM1,F2R,SNX10,S100A13,S100A6,PLSCR1,S100A4,SNTB2,YES1,DOCK5,RNF19B,FOS,CASP4,NUCB1,ENPP1,H1F0,TOB1,ACOT7,XDH |
| 4.718e-04 | -7.66 | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | 197 | 35 | 17758 | 1761 |
CPEB4,CAMKK1,ITPR2,MGST2,TRIB2,PHLDA1,TMPRSS4,CARD10,SH3KBP1,ARHGEF10L,EPCAM,DOPEY2,LLGL2,KLC3,DAPK1,TPST1,CDKN1B,CLDN4,NOTCH3,MINPP1,DLG3,MBP,SLC37A1,RC3H2,MBNL3,CYB5A,SOCS3,PTPRF,TJP3,ETS2,PPP2R5A,AXL,ITPR1,EPB41L4A,TMEM131 |
| 4.718e-04 | -7.66 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | 197 | 35 | 17758 | 1761 |
PLA2G4A,ANXA3,HEBP1,KCTD12,FAM101B,IL18R1,SIRPA,IER3,CCND1,CA2,GATA2,MITF,PCYOX1,TMEM51,SORL1,FAM102A,DAB2IP,C10orf54,PTPRE,C9orf72,ABCC1,SOCS5,HPS3,STAU2,S100A4,LITAF,DOCK5,ENDOD1,SWAP70,HLF,PRCP,ARRB1,LRRK1,GEM,CD33 |
| 4.739e-04 | -7.65 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 153 | 29 | 17758 | 1761 |
CPD,ARAP3,PAPSS2,NQO1,DNAJB2,HERC5,GDF15,SLC1A3,SEPP1,DDR1,ADAMTSL4,PHLDA1,SIRPA,SOCS3,IL17RB,PDGFA,SLCO4A1,CYP1A1,SERPINA1,HOXA9,PLK2,NETO2,VAT1,PIK3C2B,TIAM1,HSPB1,IFI6,RASGRP1,RRAGD |
| 4.754e-04 | -7.65 | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | 16 | 7 | 17758 | 1761 |
PLD1,CTGF,AGPAT2,F2RL1,MAFF,LGALS3BP,IER3 |
| 4.755e-04 | -7.65 | Pro_4_hyd_alph | interpro domains | IPR006620 | 16 | 7 | 18293 | 1814 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 4.755e-04 | -7.65 | Ez/rad/moesin-like | interpro domains | IPR000798 | 16 | 7 | 18293 | 1814 |
EZR,EPB41L5,EPB41L4B,NF2,EPB41L4A,MYLIP,FARP2 |
| 4.759e-04 | -7.65 | negative regulation of transferase activity | biological process | GO:0051348 | 328 | 53 | 16441 | 1675 |
CASP3,SPRED1,NF2,CDKN1C,UBASH3B,DNAJC3,PSME2,PSMD10,PSME1,PKN1,TRIB2,GSTP1,TFAP4,CDKN2C,PSMD1,IGF1R,PTEN,BMP7,RGS3,DUSP10,CDKN1B,SORL1,DAB2IP,BUB1,CDKN2D,SPRY2,SOCS5,CHP1,PLK1,SIRT1,AKT1,PSMB4,CDC20,PRKAR2B,PIF1,EPHA1,DUSP4,PSMA4,MAPK8IP1,SOCS3,IRS2,CDK5RAP1,PRKAG2,PTPRJ,PPP2R5A,STK38,LIMK1,CORO1C,RGS14,UBE2C,HSPB1,HIPK3,PKIA |
| 4.773e-04 | -7.65 | KEGG_GLIOMA | MSigDB lists | KEGG_GLIOMA | 65 | 16 | 17758 | 1761 |
AKT1,CALM1,PIK3R1,TP53,CALM3,PDGFB,PDGFA,CALM2,CCND1,PLCG1,IGF1R,SHC3,PTEN,PLCG2,PIK3CA,PIK3CD |
| 4.776e-04 | -7.65 | V$IK2_01 | MSigDB lists | V$IK2_01 | 258 | 43 | 17758 | 1761 |
LTBP1,BMF,ARAP3,NFKBIE,IGFBP6,RASA2,RNF182,VARS2,OSR2,ETS1,HOXB2,CYP26A1,SYTL2,NRP2,IRF2BPL,CTGF,IGF1R,RALGPS2,SHC3,PRICKLE3,ELF5,FAM20B,TFAP2A,CDKN1B,NCOA2,RBMS2,DOCK4,HES1,PDGFC,TGIF1,SAT1,COL12A1,CXXC4,KLF12,AMMECR1,PRPS2,AGBL5,OVOL1,SP6,GRAMD1C,NRGN,PKIA,JARID2 |
| 4.790e-04 | -7.64 | GNF2_HLA-C | MSigDB lists | GNF2_HLA-C | 47 | 13 | 17758 | 1761 |
HLA-B,TAPBP,HLA-E,TSC22D3,INPP5D,HLA-F,TAP1,FXYD5,ARHGDIB,HLA-C,GRK6,ARF6,HLA-A |
| 4.794e-04 | -7.64 | regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043122 | 229 | 40 | 16441 | 1675 |
PINK1,NLRX1,PSMD10,IL18,GSTP1,SLC20A1,TNFRSF19,IL18R1,NOV,CARD8,BMP7,TSPAN6,SLC44A2,DAB2IP,F2R,TRIM62,S100A13,CTH,MAP3K3,SIRT1,RHOA,TRIM8,TNIP1,RIPK2,S100A4,LITAF,PRKCQ,CD40,OPTN,GPRC5B,PELI2,PLK2,NFKBIA,SECTM1,NOD2,TLE1,NDFIP1,HSPB1,TRAF5,F2RL1 |
| 4.826e-04 | -7.64 | MODULE_126 | MSigDB lists | MODULE_126 | 175 | 32 | 17758 | 1761 |
CCNE2,FOXM1,DAP,ETV5,MGST2,CCNB1,SLC20A1,MECOM,ITGA3,UBE2T,GTF2F2,BUB1,PANX2,ETV4,ULBP2,ABCC1,CKS2,SEMA3B,PPIF,PCDH1,MFI2,ASPM,SLC25A5,CDK1,ANKRD6,AURKA,GLA,CENPE,ARPC2,NCAPG2,MELK,MAPK12 |
| 4.826e-04 | -7.64 | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | 175 | 32 | 17758 | 1761 |
TAP1,CD274,BCL2L1,HERC6,ZNF385B,OTUD1,BTG3,ITGB8,SELK,IFIT1,RASGRP1,LAMP3,RIPK2,TNIP1,PLAUR,RAPGEF2,PTGER4,IFIT3,TP53INP2,SOCS3,GALNT3,MFSD2A,SLC2A6,SIPA1L1,NFKBIA,NR4A3,NFKBIZ,IRF7,HS3ST3B1,GEM,IFIH1,EHD1 |
| 4.852e-04 | -7.63 | thyroid hormone binding | molecular function | GO:0070324 | 5 | 4 | 16491 | 1673 |
THRB,CRYM,THRA,ALDH1A3 |
| 4.856e-04 | -7.63 | Inositol phosphate metabolism | KEGG pathways | hsa00562 | 71 | 18 | 6908 | 758 |
MTM1,ALDH6A1,INPP5D,PIP4K2C,ISYNA1,PLCG1,PLCH1,PTEN,IMPAD1,PLCG2,PIK3CA,INPP4B,PIK3C2B,PIK3CD,MINPP1,PIKFYVE,ITPKA,PLCB2 |
| 4.856e-04 | -7.63 | Inositol phosphate metabolism | KEGG pathways | ko00562 | 71 | 18 | 6908 | 758 |
MTM1,ALDH6A1,INPP5D,PIP4K2C,ISYNA1,PLCH1,PLCG1,PTEN,IMPAD1,PLCG2,INPP4B,PIK3CA,PIK3C2B,PIK3CD,ITPKA,PIKFYVE,MINPP1,PLCB2 |
| 4.866e-04 | -7.63 | ERO1B (endoplasmic reticulum oxidoreductase beta) | protein interactions | 56605 | 15 | 7 | 16036 | 1726 |
PDIA3,FBXO6,PSMA4,ERO1A,PDIA4,FBXO2,GPX4 |
| 4.897e-04 | -7.62 | positive regulation of protein localization to plasma membrane | biological process | GO:1903078 | 35 | 11 | 16441 | 1675 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,EZR,GPER1,ARF6,ARHGEF16,STX3 |
| 4.897e-04 | -7.62 | positive regulation of protein localization to cell periphery | biological process | GO:1904377 | 35 | 11 | 16441 | 1675 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,EZR,GPER1,ARF6,ARHGEF16,STX3 |
| 4.926e-04 | -7.62 | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | 53 | 14 | 17758 | 1761 |
PDGFA,TNIP1,IL15RA,PSME2,NFKBIA,SDC4,TAP1,NR4A3,KLF5,DUSP4,MAFF,CD83,LAMP3,OPTN |
| 4.926e-04 | -7.62 | BOYLAN_MULTIPLE_MYELOMA_C_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_DN | 53 | 14 | 17758 | 1761 |
IRS2,PLOD2,AK7,KCNN4,SAT1,ABCB1,RAB20,KIF13A,PDE4D,EGLN3,DOCK5,SERPINB1,FZD6,KLF7 |
| 4.931e-04 | -7.61 | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | 190 | 34 | 17758 | 1761 |
CCDC109B,FRMD4A,SERPINE2,FRMD6,RNF182,TGFBR1,OSR2,WEE1,IGF1R,GNB5,KIAA1107,SPIN4,TSPAN6,NTN4,PACSIN1,DLG3,SLC12A2,TIAM1,ZNF365,CPD,GCA,MBNL3,VEZT,GGH,COL7A1,PRKAG2,KCNMB4,SWAP70,FAM110C,TBC1D4,HOOK1,CYBRD1,RRAGD,XDH |
| 4.931e-04 | -7.61 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | 190 | 34 | 17758 | 1761 |
REPS2,EPAS1,HAL,DNAJB11,EFHD2,FTH1,CTSZ,GSTP1,ADAMTSL4,IL18R1,TTYH3,SGPL1,TMCC3,ATP6V0B,UBE2J1,CD9,IRF2,DGKG,NAGA,C9orf72,CYP1B1,MAP3K3,PDGFC,MCTP1,PLSCR1,MPP1,PLEKHO1,SLC6A6,SECTM1,ZDHHC7,CTSA,ARSB,LTA4H,AHR |
| 4.956e-04 | -7.61 | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | COSMIC cancer mutations | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | 36 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 4.956e-04 | -7.61 | lobular_carcinoma_in_situ | COSMIC cancer mutations | lobular_carcinoma_in_situ | 36 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 4.994e-04 | -7.60 | FERM_M | pfam domains | PF00373 | 46 | 13 | 16629 | 1696 |
FRMPD3,EPB41L5,PLEKHH2,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 4.996e-04 | -7.60 | bone | COSMIC cancer mutations | bone | 8539 | 910 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,AASS,DNAJC3,HEXB,RET,CACNA2D2,MMADHC,DHX8,NRG2,FAM102B,DPP8,CA8,BARD1,FAM46C,CARD10,ZNF275,CDKN2C,PQLC2,KIAA1107,CYP2S1,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,RNF26,TIAM1,MGAT5,ERAP2,NWD1,SPEF2,SMARCA2,CDA,LOXL2,F12,CYP4F3,COL12A1,ABR,PLCG1,DNM1L,ANKRD6,ATP7B,LIMK1,FAM114A1,TRAF3IP1,NOD2,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,SCN5A,FAM169A,ITGA6,RAB23,MERTK,FAM21C,HPCAL4,LMNA,ELF3,RABGGTA,TFAP4,FRY,PAIP2B,FAM189A1,MEGF8,RIMS3,NEK2,MAP3K9,ALPK1,PANX2,ZMYM1,NCAM1,DGKG,NUP85,MCCC2,HPS3,SLC37A1,KIF20A,NPHP3,TP53INP2,SPTLC2,SFXN5,PLIN5,DHX32,PTPRF,CACHD1,NCOA3,SLC4A4,SETD3,ITPR1,S100A5,CLMN,NDE1,ARPC2,TMEM173,RUSC1,XDH,ADAMTS16,DOCK9,ARHGAP11A,GRHL2,NQO1,GALNT12,ACTR8,PKP2,PRSS22,NUF2,IL13RA1,GRK6,APC2,TNFSF9,REPS1,ZNF385B,MUC16,ST5,SCNN1A,CDH1,SP100,DACT1,RTKN2,RASGEF1A,LRP11,SNX10,MYT1,SCN3A,ENPP4,COL6A2,APOBEC3D,FZD4,PTPN9,SYNE2,HTATIP2,CDCA2,NUSAP1,RAB38,XRCC6BP1,ZNF618,SHROOM3,CDK19,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,RGS14,MAPK12,CTHRC1,TNRC6C,CKAP2,ESRP1,OSGIN2,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,SLC25A43,BEX2,NEO1,DTX3L,ADD3,FUT2,ITGB8,IGSF9,SLC27A6,ANKS1B,CTSC,ARSG,MGAT4A,CST3,FAM20B,KLC3,FAM102A,ADAM15,WWP1,SGCB,TPCN1,MED22,PARP9,AMOTL2,PVRL4,ADAMTS2,FMN1,TACC1,RAPGEF2,PIK3R1,ELOVL3,MRS2,GRIN1,CXorf57,SNTB1,CNTNAP1,GALNT3,PLOD2,RAB11FIP2,NR1D2,ACVRL1,CENPE,ITGAV,FHL1,DCBLD1,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,TRIM2,FAM199X,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,NDRG2,TEX2,NENF,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,SUSD2,CPNE2,SHC3,MKRN3,IL6ST,PAPSS1,TMEM143,ABCA2,DUSP10,ANO4,TLN2,MYBL1,S100A13,NEB,ZNF462,PLK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,ANLN,IDH1,SESN1,LHFPL2,DZIP1L,OPTN,KDM4D,MFAP3L,PLCH1,HS6ST1,KCNMB4,MSL1,KLF12,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,ARRDC1,KLF11,PIK3C2B,EPB41L4A,GLCCI1,PRKAA2,PARP12,RUNX2,HJURP,CHCHD7,DNAJB2,ASAH1,CNTNAP2,NCKAP1,FBLN1,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,KIF13B,AHCY,FAR2,WNT3A,PLCB2,MPHOSPH9,CKAP4,ABCC1,CHSY3,BTNL9,RGMB,MGAT4B,SCRIB,EIF2AK1,PRX,COQ10A,H1F0,COL13A1,PHLPP2,ITGA7,CSF1,NLRC5,LTBP2,ZDBF2,ATP1B3,PLD1,SEMA3A,CCNB2,NF2,UPF3B,FOXM1,TMX4,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,SYTL2,RAD23A,IER3,PDGFA,TTC21B,WDR44,EFR3A,LMO4,PLCG2,SRR,BCL6,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,MINPP1,EGLN3,SCN2A,CTDSP2,DVL2,SULF2,SIRT1,CLCN3,TMTC1,MBP,AKT1,FIGNL1,PTGER4,ACO1,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,RBL1,STK38,ADAMTS14,ANXA9,AIFM3,NDST3,CMTM4,MAN2B2,ZMAT1,BIN1,PINK1,PACSIN2,GOLIM4,CDH22,CPEB4,CD63,KLHL13,MACC1,RUSC2,ERI2,GABRG2,GTF3A,NKRF,CRABP2,VPS26A,PARM1,H1FX,SLC9A2,PPP2R3A,NRP2,M6PR,CD109,FOXP2,CDK16,ALPP,TRIM21,BUB1,ALDH7A1,KLF9,TLE6,ATP2B1,NFE2L3,HMMR,DLGAP1,FBLN5,IFITM3,GUSB,AMFR,PPARA,MAML2,COL7A1,RNPEP,BCAR1,TXNDC11,MAPK8IP1,BSDC1,PRDX4,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,ICOSLG,NDFIP1,TBC1D4,PTGES,HIPK3,ARHGEF4,GOLGB1,DIS3L,LAMP1,SUN1,GAA,SLC35D2,PPP4R4,LGR4,TTC39B,HSPG2,SSH1,ATP8A1,TSC22D3,PPFIBP2,PLXNA1,CCNB1,PJA2,SLC20A1,CENPN,CYP1A1,ANKS6,CTGF,ZNF823,STIM1,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,SNX16,IRF2,IQCD,TACSTD2,HYLS1,MTMR11,MARCH2,SMYD5,METAP2,ACVR1C,SNTB2,PBK,HSPA12A,SLC35C1,KIF13A,TNS1,GALNT7,SAV1,CCNF,TP53I3,SPNS3,POR,RBM47,PLK2,GNPTAB,LRIG1,NKD1,BMP1,PRDM5,DHTKD1,TANC2,UNC5B,WBSCR27,F2RL1,FGD1,DDX58,SEMA6B,MRC2,CDK17,FRMD4A,TBC1D1,DGKQ,SLC25A27,KIF23,SLC1A3,TNFRSF19,KIAA1161,MESDC2,MECOM,DOPEY2,RALGPS2,ITGA3,LYPD3,PIK3AP1,SLC16A6,AIM1,BDH1,RUNDC3B,DAPK1,PRKG1,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,GPR161,TRAK2,SOCS5,IGSF3,EPB41L5,KCNJ12,PRODH,B3GNT7,MFI2,TBC1D8B,PIP4K2C,FAM133B,ATP8B3,ANTXR1,NFIB,GLT8D2,FRMD4B,DGKH,GABRD,AP1AR,PRKAG2,PLEKHH2,TJP3,FAM64A,PELI2,MATN2,SLC4A3,AGBL5,FGD6,SFMBT1,CABIN1,CDK18,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,MFSD3,PLA2G4A,SLC2A4,TCTN2,REPS2,ARMCX3,TRIP10,NLRX1,CCDC110,IQGAP1,RALBP1,RPS6KA1,ATP2C2,FTH1,RNF182,CD274,TMEM170B,DDR1,AIFM2,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,APLP2,TRANK1,DOK4,CNNM4,PDE4D,LGMN,TSPAN1,PHKA2,SULT2B1,NR2C1,GPX4,MYO5B,DOCK4,SEC23A,COG2,CAPN6,FOXJ2,PANK1,UTRN,KIF1C,PRKCQ,PYGO1,ATP1B1,C15orf39,ITPR3,H2AFV,ATP10D,SP4,FZD7,NIN,EPHA10,DDOST,PPP2R5A,SLC27A1,NRG1,MLKL,SLC27A3,COBL,DENND5B,ARHGEF3,DEPDC1,CCNJL,HERC5,PBX3,CYB561,APOBEC3H,DNAH3,EFNB1,FGF19,TEAD3,TMCC3,RASSF8,E2F7,FAM111A,PHF7,PTEN,FUT8,SGK3,CD9,CCDC82,ERBB3,TRIM62,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ALDH2,B3GNT2,ARAP2,ERMAP,LONRF3,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,DIAPH2,C2orf69,YES1,LRRC1,FOS,CDK5RAP1,DCTN6,MAMDC4,ACADSB,FGFR2,ABCB1,CSTF2,ERAP1,CCDC69,GRIN2D,WDR62,SLC25A38,NCAPG2,ESPL1,MELK,JARID2,RGMA,ESYT2,EXPH5,EMX1,LTBP1,CRYM,CPT2,CAMKK1,VARS2,DNER,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,CHPF,HTR1D,ARHGEF10L,NKAIN3,ZFYVE16,SIPA1L2,ZCCHC12,ARHGEF37,DPYSL2,PHTF1,ANKFN1,DLG1,ANKRD12,TRPC1,SUN3,MYH14,TECR,SLC39A10,PTPRE,BTBD3,RASGRP1,CYP1B1,ATL1,TRIM8,ITCH,RGAG1,ROR1,PTGFRN,STK17B,MAN2A2,ZNF114,ARHGEF19,NEIL1,GPRC5B,HPSE,MADD,ZNF165,ADIPOR1,SP6,GLA,CPPED1,STARD3NL,PCSK5,NR2C2,LASP1,PPP1R2,ZNF395,SERPINE2,LRRFIP2,PEX6,BVES,ETV5,ASB9,ABCG2,FAM81A,PHLPP1,ADAMTSL4,ZNF432,AIM1L,CA2,KCNN4,COL6A1,LIMCH1,C10orf54,HLA-C,NCEH1,SLC12A2,CCDC88A,ELK3,PODXL2,GYLTL1B,PDE5A,NUBP1,C3orf58,AMDHD1,STEAP1,MFSD7,RANBP9,MUM1L1,GLCE,GNAS,XKRX,FECH,ONECUT1,SLC6A6,TMEM30A,CGREF1,SH3BP4,ALPK3,RHOBTB2,EGFL7,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,PROM2,CCNE2,LMO7,GAS2L1,NCKAP5,SORBS1,FAM92A1,MORC4,COL18A1,IL27RA,TDRKH,ARHGEF16,LRRC45,SS18,ZNF687,SETDB2,FRYL,REEP1,RPN2,EPB41L4B,ECE1,SCYL3,SEPHS1,PTPRU,GLO1,IGSF8,ERBB2IP,CD40,DOCK5,ARHGAP35,BFSP1,BHLHB9,SECTM1,TLE1,OVOL1,VSIG10,SPTBN5,CYP2U1,REEP4,ABCA1,LIFR,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,FRMD6,LRP4,ARMC7,FAM134A,COL4A5,INTS8,SBF1,NTAN1,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,RRBP1,GALNS,KIAA0319,ARVCF,IQGAP3,MYO5A,RBMS2,PGM1,PHF20L1,SUN2,RAB3B,NR4A1,ASPM,RC3H2,SYBU,OGDHL,LRRC66,KLHL2,SWAP70,C2orf70,TRIM69,RND3,PRCP,DHRS2,OTUB2,UACA,ARRB1,ZMIZ1,PLOD3,SOX8,L1CAM,RAB3IL1,ABCG1,SNPH |
| 5.019e-04 | -7.60 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | 91 | 20 | 17758 | 1761 |
GCA,CTHRC1,BVES,LMCD1,KCTD12,IL13RA1,EPHA1,ATP1B1,FOS,HDAC9,ENPP1,METTL7A,NPNT,FLRT3,CDH3,IFIT1,TINAGL1,ABCA1,L1CAM,SEMA3B |
| 5.046e-04 | -7.59 | limb development | biological process | GO:0060173 | 171 | 32 | 16441 | 1675 |
RUNX2,GRHL2,ITGA6,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,MEGF8,FRAS1,BMP7,IMPAD1,TFAP2A,BAX,TWIST1,ECE1,CYP26B1,SALL4,FMN1,RC3H2,PITX2,GNAS,FGFR2,HOXA9,TRAF3IP1,HDAC1,OSR1,RARG,HOXC13,PCSK5 |
| 5.046e-04 | -7.59 | appendage development | biological process | GO:0048736 | 171 | 32 | 16441 | 1675 |
RUNX2,GRHL2,ITGA6,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,MEGF8,FRAS1,BMP7,IMPAD1,TFAP2A,BAX,TWIST1,ECE1,CYP26B1,SALL4,FMN1,RC3H2,PITX2,GNAS,FGFR2,HOXA9,TRAF3IP1,HDAC1,OSR1,RARG,HOXC13,PCSK5 |
| 5.051e-04 | -7.59 | cell-matrix adhesion | biological process | GO:0007160 | 122 | 25 | 16441 | 1675 |
SGCE,BCAM,SORBS1,FBLN5,RHOA,CD63,ITGA6,TESK2,EMP2,DDR1,DAG1,EPDR1,ITGA3,MUC4,HPSE,CTGF,ITGB8,NPNT,LYPD3,COL13A1,ITGA7,ADAM15,ITGAV,CTTN,TIAM1 |
| 5.065e-04 | -7.59 | cell-substrate junction | cellular component | GO:0030055 | 399 | 61 | 17570 | 1756 |
CD99,LMO7,LASP1,FBLIM1,SORBS1,PACSIN2,MRC2,ADD1,HSPG2,ITGA6,IQGAP1,SDC4,PDIA3,KIF23,NCKAP1,SDC1,SH3KBP1,TNS3,ITGA3,CDH1,FLRT3,CD9,IRF2,DIXDC1,CTTN,TLN2,CHP1,EPB41L5,RHOA,SNTB2,PLAUR,SYNE2,EZR,TNS1,ERBB2IP,YES1,SNTB1,AIF1L,ALCAM,BCAR1,DAG1,ARHGAP24,SCARB2,RPL12,JAK1,RND3,PVRL2,ITGA7,LIMK1,PTK7,CORO1C,TRIOBP,ITGAV,FHL1,HMGA1,ARPC2,ARF6,HSPB1,AFAP1,L1CAM,CAPN1 |
| 5.074e-04 | -7.59 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | MSigDB lists | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | 78 | 18 | 17758 | 1761 |
MYL9,BIN1,LTBP1,FBLN5,EPAS1,CD82,SOX9,SYBU,LMCD1,CD83,SCNN1A,MLPH,AOX1,SORL1,TSPAN13,EPB41L4B,LTBP2,IFIH1 |
| 5.095e-04 | -7.58 | SUBTIL_PROGESTIN_TARGETS | MSigDB lists | SUBTIL_PROGESTIN_TARGETS | 36 | 11 | 17758 | 1761 |
MAP3K3,CCND1,CDKN1C,CYR61,IL6ST,RPS6KA1,ECI2,BCAR1,GM2A,H1FX,HDAC9 |
| 5.098e-04 | -7.58 | RNGTGGGC_UNKNOWN | MSigDB lists | RNGTGGGC_UNKNOWN | 730 | 100 | 17758 | 1761 |
EMX1,HOXB7,EPAS1,CAMKK1,NRG2,PDGFB,LTBP3,SH3KBP1,CCND1,CALM2,ST5,WDR44,DPYSL2,FABP6,VAT1,ACSL4,PACSIN1,DLG3,PTPRE,SMYD5,BTBD3,DVL2,SEMA3B,ATL1,KCNIP3,CELSR2,CAPN6,PANK1,RGAG1,KIF1C,TMEM151A,KLK6,IDH1,SP4,PGF,MAN2A2,KLF12,CORO1C,OVOL1,ADAMTS14,NRG1,KLF5,EFNA5,RGS14,AIFM3,NRGN,COBL,PRR15,COL9A3,PCOLCE,GGA1,CALM3,PDIA3,HMGN3,EFNB1,SIX4,WWP2,ADD3,ITGB8,FRY,RALGPS2,MEGF8,FLRT3,CALD1,RANBP1,RRBP1,FAM13B,RUNDC3B,SORL1,CITED2,NCAM1,C9orf72,CKAP4,CCDC88A,KDELR1,SOCS5,SUN2,B3GNT7,ADAMTS2,LONRF3,NR3C1,NR4A1,BCL9,CALM1,ELK1,NFIB,PRX,GNAS,PITX2,NUCB1,SYT7,PRPS2,NR4A3,CCDC69,LTBP2,FZD5,CEP41,RARG,KLF7,PROM2 |
| 5.116e-04 | -7.58 | Signaling by Insulin receptor | REACTOME pathways | R-HSA-74752 | 304 | 51 | 8202 | 867 |
PRKAA2,SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,AKT1,RAPGEF2,CALM1,PIK3R1,GRIN1,STRADB,DUSP4,PSMA4,RHEB,RASA1,IRS2,PRKAG2,PPP2R5A,JAK1,FGFR2,CAB39,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,GAB1,RRAGD |
| 5.138e-04 | -7.57 | cell cortex | cellular component | GO:0005938 | 234 | 40 | 17570 | 1756 |
LASP1,FBLIM1,NF2,TRIP10,EPS8,ITPR2,GPSM2,SPTB,ADD3,SCNN1A,CDH1,CTGF,FRY,STIM1,LLGL2,CABP1,FRYL,CALD1,EXOC8,CTTN,MYRIP,GM2A,TLE6,MYO5B,RHOA,MPP1,SEPT6,ITCH,EZR,ANLN,PLEKHH2,FGFR2,FAM110C,SPTBN5,ARF6,SHROOM2,NDFIP1,NRBP1,COBL,MELK |
| 5.140e-04 | -7.57 | PHOSPHOLIPID_TRANSPORTER_ACTIVITY | MSigDB lists | PHOSPHOLIPID_TRANSPORTER_ACTIVITY | 12 | 6 | 17758 | 1761 |
ATP8B1,PITPNA,PLSCR1,PCTP,ABCA1,ABCG1 |
| 5.140e-04 | -7.57 | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | MSigDB lists | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | 12 | 6 | 17758 | 1761 |
NUSAP1,CENPA,ANLN,UBE2C,CCNB2,ASPM |
| 5.140e-04 | -7.57 | MODULE_190 | MSigDB lists | MODULE_190 | 12 | 6 | 17758 | 1761 |
LTBP1,NOV,IGFBP2,CTGF,IGFBP6,CYR61 |
| 5.142e-04 | -7.57 | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | MSigDB lists | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | 183 | 33 | 17758 | 1761 |
DDX58,PARP12,IL15,HAPLN3,SDC4,OSGIN2,CD274,HERC6,TNFSF9,DTX3L,PDGFA,FAM46A,TRIM21,OAS3,ATP2B1,LAMP3,STAT4,NUB1,C3orf52,CD40,SAV1,RNF19B,SOCS3,STK17A,FAS,PVRL2,SLC2A6,NMI,NFKBIA,NLRC5,HS3ST3B1,CMPK2,IFIH1 |
| 5.158e-04 | -7.57 | long-chain fatty acid metabolic process | biological process | GO:0001676 | 102 | 22 | 16441 | 1675 |
PLA2G4A,FADS2,FAM213B,ELOVL3,CYP4F3,MAPKAPK2,CYP1A1,SLC27A6,FAAH,CYP2S1,SLC27A1,ABCD1,CYP2U1,ACSL4,LTA4H,SLC27A3,PTGES,ACOT7,MYO5A,ABCC1,GPX4,CYP1B1 |
| 5.190e-04 | -7.56 | embryonic placenta morphogenesis | biological process | GO:0060669 | 25 | 9 | 16441 | 1675 |
NCOA3,GRHL2,CDKN1C,CYR61,FGFR2,ST14,SPINT2,FZD5,SOCS3 |
| 5.196e-04 | -7.56 | V$HNF3ALPHA_Q6 | MSigDB lists | V$HNF3ALPHA_Q6 | 198 | 35 | 17758 | 1761 |
REPS2,CHCHD7,IL18,NEO1,SCML1,FOXP2,HSF2,ITGA3,CYR61,PRICKLE3,CALD1,VASN,BDH1,KLF3,SGK3,SGK1,TWIST1,PDE4D,SMARCA2,SSH3,SLC39A8,RGAG1,H2AFV,GABARAPL1,PITX2,KLF12,RBM47,COL13A1,NKD1,NR4A3,TLE1,ADAMTS14,C1orf43,TOB1,RGMA |
| 5.212e-04 | -7.56 | glycosphingolipid metabolic process | biological process | GO:0006687 | 70 | 17 | 16441 | 1675 |
UGT8,HEXB,ASAH1,ARSK,CPTP,B4GALNT1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,CTSA,GLA,ARSB,ST3GAL1,NAGA,GM2A |
| 5.225e-04 | -7.56 | positive regulation of endopeptidase activity | biological process | GO:0010950 | 150 | 29 | 16441 | 1675 |
SIRT1,CASP3,NKX3-1,RHOA,ACVR1C,DAP,PSME2,CASP9,RET,PSME1,SLC11A2,BCAP31,FAS,TFAP4,CARD8,CTGF,CYR61,CTSC,NGFRAP1,DAPK1,BAX,ARRB1,CDKN1B,GPER1,WNT3A,EGLN3,MAP3K5,F2R,XDH |
| 5.240e-04 | -7.55 | extracellular region | cellular component | GO:0005576 | 4445 | 502 | 17570 | 1756 |
LAMP1,GAA,TXN,KLK10,HSPG2,IL15RA,ATP8A1,DNAJC3,HEXB,PPFIBP2,FBXO2,NRG2,PSME1,IL18,LYNX1,NANS,PLXNA1,VASH1,CMTM6,LTBP3,GRM5,NCS1,EPDR1,CALM2,PSMD1,MUC4,CTGF,CABP1,ALDH1A3,SERINC2,AOX1,CRY2,TACSTD2,MTMR11,SEMA3G,MANF,TINAGL1,ZBTB18,MGAT5,LAMP2,LOC81691,SNTB2,SH3BGRL,HSPA12A,CDA,PRKAR2B,LOXL2,F12,GALNT7,SLC25A5,TP53I3,ARF4,COL12A1,PGF,ENPP1,CARHSP1,PTER,BMP1,SERPINB6,SERPINI1,ARF6,HSPB1,ALDH6A1,ITGA6,HLA-E,RAB23,KIF23,NDUFA4,SLC1A3,MERTK,TTYH3,PRRG4,GNS,DOPEY2,ITGA3,CYR61,SNX18,LYPD3,MEGF8,ATP5H,RPL39,VASN,FLRT3,PCYOX1,SORL1,OSTF1,CD70,CYSRT1,MYDGF,NCAM1,ULBP2,C9orf72,RIMS2,GFPT1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,NPC2,ANTXR1,JADE2,GNA11,PSMA4,STX3,CYB5A,FRMD4B,FAS,PTPRF,SCARB2,NCOA3,PRKAG2,SLC4A4,SEMA4D,ISM1,MATN2,MDH1,KLK7,MAL2,GDF11,ARPC2,CFAP20,SERPINB1,XDH,ADAMTS16,EHD1,MTM1,SLC2A4,NQO1,ST14,S100A11,TRIP10,BROX,CD82,IQGAP1,PRSS22,FTH1,KCTD12,CD274,MVB12B,AIFM2,PRKACA,DDR1,TNFSF9,TMPRSS4,EPS8L2,NOV,APLP2,MUC16,SCNN1A,CDH1,ENPP5,DAB2IP,ACSL4,EPHB4,TSPAN1,DLG3,RAB27B,LGMN,SULT2B1,NAGA,SEMA3B,GPX4,MYO5B,ENPP4,C6orf1,COL6A2,FZD4,SYNE2,CYS1,LYRM1,UTRN,ATP1B1,ALCAM,H2AFV,SNX12,SP4,CMTM7,EPHA10,ALDH3B1,STK26,AXL,NRG1,ISOC1,WASF3,CTHRC1,PCOLCE,IGFBP6,HAPLN3,EPS8,HABP4,SDC4,PDIA3,CTSZ,NUCB2,SEPP1,SPR,GSTP1,SRPX2,FGF19,EFNB1,LGALS3BP,HLA-A,WWP2,CXCL16,FUT2,ITGB8,CTSC,ARSG,PTEN,MGAT4A,CST3,FJX1,FUT8,CD9,BAX,ADAM15,SLC44A2,WWP1,IGFBP2,ERBB3,TAGLN2,S100A6,CRTAP,PVRL4,ADAMTS2,PDGFC,ALDH2,SHMT1,B3GNT2,PLSCR1,GRIN1,FURIN,PARP4,C1GALT1C1,AK4,C2orf69,BLVRA,YES1,AIF1L,ARSK,CRISPLD2,GPLD1,GALNT3,NUCB1,TIMP3,RPL12,ACADSB,PLOD2,FGFR2,SYT7,DBI,ABCB1,ERAP1,ITGAV,ARSB,CYBRD1,ACOT7,RGMA,TLL2,LTBP1,BCAM,GNPDA1,CRYM,HEBP1,CUL4B,LMCD1,NDRG2,F11R,NENF,MPP5,PDGFB,SDC1,ERP29,SUSD2,EPCAM,CPNE2,RAB15,NPNT,METTL7A,IL6ST,TSPAN6,DPYSL2,SLC44A1,PAPL,RBBP8NL,DLG1,AKR1B1,NTN4,RP2,MYH14,CTTN,NEB,S100A13,THRB,NLRP4,CD55,ITCH,CR2,EZR,KLK6,ARHGDIB,IDH1,CDK1,RHEB,DPYSL3,KDM4D,MDK,ZNF114,GPRC5B,HPSE,UEVLD,CAB39,ARRDC1,GLA,MYL12B,CAPN1,CPPED1,PCSK5,GRN,PRSS8,LASP1,FAM213B,SERPINE2,LGALS3,FXYD3,CALM3,ASAH1,PM20D2,RAB6A,NCKAP1,ADAMTSL4,FBLN1,ANO1,CA2,FRAS1,COL6A1,AHCY,HLA-C,WNT3A,SLC12A2,ALDH3A2,CKAP4,ABCC1,PCBP3,VWA1,SCRIB,NUBP1,C3orf58,MUM1L1,GNAS,MAPKAPK2,EPN3,PVRL2,COL13A1,PLPP3,CSF1,CGREF1,PRPS2,SH3BP4,FAM213A,EGFL7,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,SEMA3A,APOL2,COL16A1,PROM2,UGP2,IL15,P3H2,PSME2,XYLT1,CTDSPL,HDAC11,COL18A1,MRAS,PDGFA,SVBP,ARTN,EFR3A,PLCG2,VAT1,GOT1,GLB1L2,ECE1,NOTCH3,OAS3,MINPP1,LMAN1,F2R,PDIA6,GM2A,CTH,CHP1,SULF2,CPD,GCA,TIMP2,FIGNL1,S100A4,ACO1,GLO1,IGSF8,ERBB2IP,CD40,MYL12A,DAG1,IDE,ATP1A1,PTPRJ,BHLHB9,MMP17,SECTM1,ADAMTS14,EFNA5,SPTBN5,ANXA9,ST3GAL1,LTA4H,LIFR,CMTM4,MAN2B2,COL9A3,ANXA3,PACSIN2,ENO2,ADGRG1,CD63,TSPAN15,RUSC2,BLVRB,CDCA8,GDF15,COL4A5,NOTUM,CRABP2,VPS26A,DNAJB9,NRP2,SIRPA,TMEM63A,CD109,IRF2BPL,IL17RB,TAF1B,MLPH,A4GALT,BMP7,LYPD6,GALNS,FAM63A,ALDH7A1,ATP2B1,MYO5A,GCNT1,FAH,PGM1,SYPL1,RAB3B,RHOA,FBLN5,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,GGH,RNPEP,LEPR,SCRN2,PRDX4,ENDOD1,FUCA1,CTSL,HLA-B,GAREM2,FAT4,SERPINA1,RND3,TWSG1,SCG2,DHRS2,PRCP,CTSV,SPINT2,RAP2C,TMC5,PGRMC1,UACA,SH3BGRL2,ICOSLG,PLOD3,NDFIP1,TBC1D4,NXPE3,CD33 |
| 5.243e-04 | -7.55 | regulation of neurogenesis | biological process | GO:0050767 | 620 | 89 | 16441 | 1675 |
EMX1,FOXO6,NF2,SSH1,RET,EPHA4,TP53,PLXNA1,CAMK1D,NCS1,GRM5,DPYSL2,IL6ST,BCL6,DUSP10,DAB2IP,DIXDC1,CTTN,NOTCH3,SEMA3G,PACSIN1,TIAM1,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,CDK1,RHEB,ARHGAP35,DPYSL3,GPRC5B,BHLHB9,PTK7,LIMK1,PLK2,SIPA1L1,EFNA5,NRG1,ITPKA,ARF6,RGS14,COBL,LZTS1,GRN,BIN1,SEMA6B,SERPINE2,ADGRG1,CIT,LRP4,ETV5,SOX9,CRABP2,ITGA3,PTEN,GATA2,KIF13B,BMP7,MYCL,MEGF8,KIAA0319,SORL1,TNFRSF12A,WNT3A,RIMS2,TLE6,CCDC88A,HES1,TGIF1,RHOA,MMD,ASPM,RAPGEF2,GRIN1,HMG20B,CDK5R1,CDK5RAP1,PTPRF,SEMA4D,CSF1,TMEM30A,GPER1,GDF11,SOX8,ARSB,SEMA3A,L1CAM |
| 5.269e-04 | -7.55 | SH3 domain binding | molecular function | GO:0017124 | 116 | 24 | 16491 | 1673 |
DOCK4,PLSCR1,FMN1,CRB3,INPP5D,SH3BGRL,CIT,PTTG1,CASP9,BCAR1,REPS1,SIRPA,SH3KBP1,DPYSL3,CNTNAP1,ELMO2,SH3BP1,FUT8,ADAM15,SH3BGRL2,ESPN,DAB2IP,OSTF1,PDE4D |
| 5.296e-04 | -7.54 | PROTEIN_TRANSPORT | MSigDB lists | PROTEIN_TRANSPORT | 154 | 29 | 17758 | 1761 |
NFKBIE,AKT1,PEX6,COG2,GGA1,PDIA3,STRADB,ICMT,BARD1,ERP29,AIP,ZFYVE9,APPBP2,OPTN,ATG4A,KLHL2,ZFYVE16,AP1M2,CDH1,KIF13B,BCL6,CTSA,LTBP2,F2R,TRAM1,KDELR1,ABCG1,ATG4D,MDFI |
| 5.324e-04 | -7.54 | cellular response to organonitrogen compound | biological process | GO:0071417 | 612 | 88 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,SSH1,PSME2,NRG2,ERBB2,PSME1,ITPR2,BCL2L1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,CDH1,SHC3,KLF3,PIK3CA,AKR1B1,DAB2IP,GOT1,PDE4D,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,EZR,PRKAR2B,POR,CASP4,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,NOD2,CAB39,EIF4EBP2,SPTBN5,NRG1,GAB1,RRAGD,PRKAA2,CPEB4,RASA2,SOX9,CALM3,PSMD10,GABRG2,FGF19,HDAC9,IGF1R,COL6A1,ERBB3,NCAM1,MYO5A,PDGFC,RASGRF1,SHMT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,SH3BP4,NR4A3,NR4A2,GRIN2D,GPER1,TBC1D4,JAK3,CPEB2,COL16A1 |
| 5.349e-04 | -7.53 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | 176 | 32 | 17758 | 1761 |
ZNF395,CKAP2,C6orf106,CALM3,TRIB2,FAM46C,CALM2,MARCH8,WEE1,ADD3,SP100,PLCG2,PIK3CA,CDKN1B,PIKFYVE,ATP2B1,SMAGP,DDB2,HES1,SYPL1,CD55,CALM1,EZR,CASP4,CD83,IRS2,BANK1,SWAP70,SIPA1L1,PIK3C2B,TRAF5,DOCK9 |
| 5.391e-04 | -7.53 | RICKMAN_METASTASIS_DN | MSigDB lists | RICKMAN_METASTASIS_DN | 244 | 41 | 17758 | 1761 |
GAS2L1,AVPI1,TXN,S100A11,FXYD3,TAP1,IL18,BCL2L1,SDC1,ADAMTSL4,S100A2,TNFSF9,PRRG4,LMNA,SGPL1,TYMP,ZDHHC12,A4GALT,ADAM15,MAPK11,OSTF1,TAGLN2,ALS2CL,S100A6,IGSF3,ATG4D,PVRL4,PRODH,RHOA,C15orf39,RNF19B,ZBTB7B,MAPKAPK2,KCNK1,CORO1C,SECTM1,NLRC5,RGS14,SLC27A3,PROM2,MAPK12 |
| 5.426e-04 | -7.52 | occluding junction | cellular component | GO:0070160 | 111 | 23 | 17570 | 1756 |
DDX58,AMOTL2,ILDR1,FRMD4A,CRB3,BVES,RAPGEF2,TGFBR1,F11R,MPP5,EPCAM,CCND1,TJP3,TBCD,RAP2C,DLG1,CLDN4,POF1B,EPB41L4B,FZD5,DLG3,SHROOM2,OCLN |
| 5.439e-04 | -7.52 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | 191 | 34 | 17758 | 1761 |
LAMP1,LGALS3,HEXB,ASAH1,KCTD12,IL18,CTSZ,DSE,BMP2K,DNAJB9,ATP6V0B,FAM46A,PTEN,CTSC,METTL7A,KCNS3,SYK,NAGA,GCA,MCTP1,MMD,CDA,RAB38,FNDC3A,TCEAL4,ARRB1,ADIPOR1,KLF11,GLA,PLOD3,PLIN3,MAP3K5,ABCA1,CD33 |
| 5.439e-04 | -7.52 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | 191 | 34 | 17758 | 1761 |
ANXA3,ATP9A,SDC4,NDC80,CDCA8,PHLDA1,IER3,APOBEC3B,ATP6V0B,AKR1B1,BUB1,AHCY,PDE4D,ALDH3A2,SCN3A,FAH,CKS2,PPIF,NFE2L3,TIMP2,PBK,PLAUR,GGH,PDK3,DUSP4,GTF2A2,KIF11,STEAP1,CDK1,RAB11FIP1,SERPINB1,NCAPG2,IFI6,ACOT7 |
| 5.439e-04 | -7.52 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_DN | 191 | 34 | 17758 | 1761 |
ARHGEF3,TXN,TBC1D1,RUSC2,EPHA4,OSGIN2,GABRG2,NDRG2,PLXNA1,KREMEN1,IER3,ZFYVE16,ATP6V0B,EFR3A,DPYSL2,BHLHE41,PAPSS1,OSTF1,ACSL4,IFITM3,PLAUR,AMFR,SAT1,DIAPH2,ARFRP1,RAD17,FZD7,HLA-B,RBL1,COL13A1,NFKBIA,HDAC1,ITGAV,GEM |
| 5.439e-04 | -7.52 | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 191 | 34 | 17758 | 1761 |
CENPI,CUL4B,MIER3,KIF23,GPSM2,VASH1,BCAP31,BMP2K,ZDHHC21,SNX18,SNX16,SGCB,SLC12A2,SNX10,TIAM1,MYO5A,TRAK2,CKS2,CENPA,PLSCR1,RAPGEF2,CDC20,ACO1,FBXO9,CCDC34,C2orf69,ANLN,FRMD4B,NIN,IDE,SLC25A4,SLC9A6,ITPR1,CSTF2 |
| 5.444e-04 | -7.52 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | MSigDB lists | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 105 | 22 | 17758 | 1761 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,PRKACA,CDK1,SH3KBP1,CALM2,PLCG1,ADRBK1,PTEN,LRIG1,PIK3CA,CDKN1B,SPRY2,GAB1 |
| 5.458e-04 | -7.51 | PROTEIN_KINASE_TYR | prosite domains | PS00109 | 94 | 21 | 11866 | 1235 |
LMTK3,TESK1,EPHA4,RET,ERBB2,TESK2,TEC,ROR1,YES1,EPHA1,DDR1,MERTK,IGF1R,JAK1,FGFR2,AXL,PTK7,RYK,EPHB4,JAK3,SYK |
| 5.459e-04 | -7.51 | soft_tissue | COSMIC cancer mutations | soft_tissue | 6065 | 662 | 17775 | 1757 |
HECA,ACACB,ADD1,AASS,SLC25A13,DNAJC3,HEXB,RET,FBXO2,NRG2,SYTL4,CA8,CARD10,LTBP3,EPDR1,CDKN2C,CABP1,PAQR5,ALDH1A3,KLF3,CRY2,TIAM1,MGAT5,APOBEC3G,ERAP2,DNAAF3,NWD1,SPEF2,SMARCA2,TNIP1,CDA,LOXL2,PPP1R14C,COL12A1,PIAS3,ENPP1,PLCG1,DNM1L,ANKRD6,ATP7B,FAM114A1,NOD2,GAB1,SCN5A,ALDH6A1,ITGA6,SOX9,RAB23,SLC36A4,MERTK,FAM21C,LMNA,MARCH8,FRY,FAM189A1,MEGF8,FLRT3,MAP3K9,CADPS2,ALPK1,ZMYM1,PPP6R1,MCCC2,PAQR7,SLC37A1,STAT4,MYBL2,GNA11,NCOA3,ETS2,SEMA4D,ITPR1,DRP2,TMEM173,XDH,ADAMTS16,DOCK9,MTM1,PAPSS2,GALNT12,PTTG1,RGS20,TESK2,PKP2,GRK6,APC2,TNFSF9,ZNF385B,RCN1,MUC16,RNF220,CDH1,SH3BP1,RTKN2,MYT1,SCN3A,ENPP4,MX1,CAMSAP3,COL6A2,RIPK2,PTPN9,SYNE2,NFIX,CDK19,WFS1,CORO1C,SLC9A6,PLEKHG1,CTHRC1,ESRP1,RASSF7,NUCB2,PLPPR4,GSTP1,ETS1,SRPX2,BEX2,HOXB2,NEO1,CXCL16,ADD3,ITGB8,ANKS1B,ARSG,FAM102A,TMBIM6,IGFBP2,NPTXR,TPCN1,PARP9,AMOTL2,LCA5,FMN1,MFSD2B,PIK3R1,MRS2,MYEOV,SNTB1,GALNT3,PLOD2,RAB11FIP2,ACVRL1,DBI,PPM1H,CENPE,ITGAV,FHL1,USF2,TMEM131,BCAM,KIAA1462,CUL4B,FHDC1,ARFGEF1,TEX2,NENF,ITPR2,NUP62CL,SPTB,SUSD2,SHC3,PAPSS1,SLC44A1,TMEM143,ABCA2,ANO4,TLN2,TRAM1,NEB,CCDC38,ZNF462,THRB,MCTP1,CD55,EZR,CR2,IDH1,DZIP1L,OPTN,KDM4D,HS6ST1,PLCH1,KCNMB4,MAP2,P4HA2,HOXA9,ZNF367,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,PRSS8,LGALS3,UBASH3B,ZCCHC24,RASA2,PDCL,HES2,CNTNAP2,FBLN1,ANO1,TNS3,DAZAP1,UBE2Q2,IGF1R,FRAS1,TBCD,MDFIC,PIM1,PLCB2,ALDH3A2,DPYSL5,CHSY3,CORO2A,MGAT4B,SPATA13,SCRIB,TCF7,EIF2AK1,PRX,RASGRP2,H1F0,COL13A1,ITGA7,PHLPP2,SLC2A6,NLRC5,LTBP2,PLD1,ZDBF2,USP43,NF2,UPF3B,XYLT1,TP53,ERBB2,SLC7A2,CYP26A1,SYTL2,IER3,PDGFA,WDR44,PLCG2,PLK4,BCL6,CDH3,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,CPD,PPIF,CLCN3,TMTC1,AKT1,ACO1,PTGER4,ATP13A2,DNAJC10,DUOX1,PTPRJ,C19orf66,ABHD12,PTK7,STK38,ADAMTS14,IRF7,EFNA5,ANXA9,ST3GAL1,LTA4H,COL9A3,PACSIN2,TM2D2,GOLIM4,CDH22,KLHL13,MACC1,RUSC2,GNE,GDF15,CRABP2,DSE,LBR,SLC9A2,PPP2R3A,FZD6,SH2D4A,CD109,FOXP2,TFAP2A,FAM63A,SGK1,TSPAN13,BUB1,GCNT1,IGDCC4,NFE2L3,DLGAP1,HMMR,FBLN5,MOSPD2,NR3C1,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,FNDC3A,RNPEP,BBS2,TXNDC11,BCAR1,BANK1,SERPINA1,FAT4,TWSG1,SCG2,NAT1,NETO2,CLIP4,PPP2R3C,ICOSLG,TBC1D4,PTGES,ARHGEF4,GOLGB1,GAA,HSPG2,SSH1,LGR4,TSC22D3,ATP8A1,PPFIBP2,TAP1,PLXNA1,VASH1,FAM101B,SLC9A7,CYP1A1,OSBPL3,RGS3,PIK3CA,KCNS3,AOX1,SNX16,ATRNL1,HYLS1,MTMR11,RCAN3,SGCE,SPATA18,ACVR1C,CASP9,NBPF3,TNS1,KIF13A,CCNF,POR,AHRR,PLK2,GNPTAB,FAM110C,PRDM5,DHTKD1,TANC2,TRAF5,LZTS1,FGD1,DDX58,FRMD4A,TBC1D1,DGKQ,KIF23,SLC1A3,KIAA1161,MECOM,DOPEY2,RALGPS2,CYR61,ZNRF2,BDH1,AIM1,OPN3,PRKG1,SORL1,CACNA1D,C8orf58,PIKFYVE,RIMS2,SOCS5,IGSF3,EPB41L5,GFPT1,KCNJ12,FADS2,PRSS23,MFI2,ADCK3,MICB,AMER1,ATP8B3,ANTXR1,FRMD4B,FAS,DGKH,AP1AR,SLCO4A1,PLEKHH2,PRKAG2,TJP3,FAM64A,FAAH,DCK,AGBL5,FAM83D,PCDH19,CABIN1,PER3,PLIN3,MAP3K5,IFIH1,EHD1,PLA2G4A,SPRED1,TCTN2,NLRX1,IQGAP1,DDIT4L,KCTD12,RNF182,CD274,CYP39A1,ZFYVE9,EPS8L2,APLP2,ACAP2,FAM46A,PHKA2,LGMN,NR2C1,NAGA,ATG4D,MYO5B,DOCK4,SEC23A,COG2,FOXJ2,UTRN,PRKCQ,PYGO1,ITPR3,ALCAM,TRIQK,ATP10D,ZNF469,CMTM7,NIN,EPHA10,JAK1,TRIOBP,ZNF704,FAM195A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,COBL,DENND5B,PCOLCE,ATP9A,CENPI,EPS8,PBX3,CYB561,APOBEC3H,DNAH3,TMEM87B,PTEN,FJX1,FUT8,ATP8B1,ERBB3,TRIM62,NCOA2,PDGFC,TGIF1,ARHGEF28,SHMT1,ARAP2,FURIN,DIAPH2,C2orf69,LRRC1,GRTP1,AIF1L,CDK5RAP1,MAMDC4,FGFR2,ABCB1,ERAP1,PGM2L1,GRIN2D,FZD5,NCAPG2,ARSB,ESPL1,OCLN,DEF6,JARID2,RGMA,LTBP1,NMRK1,CPT2,CAMKK1,VARS2,MPP5,DNER,CACNB4,KREMEN1,TMC1,PTCHD4,SH3KBP1,NKAIN3,ARHGEF10L,SIPA1L2,HSF2,LRRC6,ARHGEF37,TSPAN6,ANKFN1,PHTF1,DLG1,TRPC1,POF1B,MYH14,SLC39A10,TECR,MYRIP,CYP1B1,ATL1,RGAG1,ADRBK2,NEIL1,HPSE,MADD,RAP1GAP,CAPN1,CPPED1,GRN,FAM213B,ARAP3,PEX6,PYROXD2,ABCG2,CALM3,PHLPP1,ADAMTSL4,KCNN4,COL6A1,FXYD5,LIMCH1,ZRANB1,CCDC88A,PODXL2,GYLTL1B,BTN3A2,PDE5A,VWA1,HEATR5A,RANBP9,MFSD7,MUM1L1,GNAS,FECH,ONECUT1,CGREF1,RHOBTB2,YOD1,DONSON,PITPNA,SHROOM2,JAK3,GAS2L1,LMO7,CCNE2,NCKAP5,SORBS1,PDIA5,MORC4,COL18A1,ARHGEF16,SLC25A48,SS18,ZNF687,ARTN,FRYL,DIXDC1,ECE1,PTPRU,SLC39A8,OSTM1,DUSP4,DOCK5,FANCE,ARHGAP35,ALDH5A1,BFSP1,TLE1,SPTBN5,CYP2U1,REEP4,ABCA1,GLIS3,ARHGEF11,LRP4,MIER3,COL4A5,NOTUM,SBF1,TMEM63A,HDAC9,KIF5B,IL17RB,IRF2BPL,CARD8,ADORA1,MLPH,LLGL2,BMP7,TOX2,KIAA0319,IQGAP3,C12orf75,MYO5A,SUN2,ASPM,DEPDC4,GCLC,NR4A1,RC3H2,SYBU,LRRC66,OGDHL,TTC7A,LEPR,ARHGAP24,HLA-B,RAP2C,UACA,GRAMD1C,SOX8,PLOD3,AHR,L1CAM |
| 5.466e-04 | -7.51 | transforming growth factor beta binding | molecular function | GO:0050431 | 16 | 7 | 16491 | 1673 |
CD109,TGFBR1,LTBP1,ITGAV,ACVRL1,LTBP3,VASN |
| 5.518e-04 | -7.50 | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | 140 | 27 | 17758 | 1761 |
PRKAA2,THRB,CEP70,ALDH6A1,AASS,C5orf30,COX6C,OAT,ZFAND5,TSPAN7,CYB5A,SCML1,GABARAPL1,SLC25A36,GNAS,APLP2,IGF1R,UAP1,BMP7,ITPR1,SRR,DHTKD1,ECI2,KLF9,GAD1,ISOC1,CTH |
| 5.610e-04 | -7.49 | signet_ring_adenocarcinoma | COSMIC cancer mutations | signet_ring_adenocarcinoma | 21 | 8 | 17775 | 1757 |
CDH1,AKT1,PTEN,SDC4,PIK3CA,TP53,ERBB2,EZR |
| 5.610e-04 | -7.49 | stomach-carcinoma-signet_ring_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-signet_ring_adenocarcinoma | 21 | 8 | 17775 | 1757 |
CDH1,AKT1,PTEN,SDC4,PIK3CA,TP53,ERBB2,EZR |
| 5.618e-04 | -7.48 | negative regulation of immune effector process | biological process | GO:0002698 | 96 | 21 | 16441 | 1675 |
CD55,LGALS3,NLRX1,ITCH,MICB,HLA-E,TAP1,ABR,HLA-A,HLA-B,TSPAN6,TRAF3IP1,NOD2,BCL6,TMBIM6,DUSP10,C10orf54,IFIT1,NDFIP1,JAK3,SOCS5 |
| 5.635e-04 | -7.48 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 260 | 43 | 17758 | 1761 |
PCOLCE,ENO2,FRMD6,PYROXD2,COL18A1,S100A2,SRPX2,LGALS3BP,SIRPA,SGPL1,B3GALNT1,ADD3,SCNN1A,CTGF,CALD1,COL6A1,DAPK1,RAB20,IGFBP2,PIK3CD,LGMN,NCAM1,SNX10,SULF2,MX1,NFE2L3,COL6A2,SPATA18,NR3C1,SEPT6,CD83,MDK,FUCA1,HLA-B,ENPP1,TIMP3,PLOD2,PLK2,STK38,MATN2,LRIG1,UACA,SHROOM2 |
| 5.635e-04 | -7.48 | V$AP1_C | MSigDB lists | V$AP1_C | 260 | 43 | 17758 | 1761 |
SPRED1,CMAS,LRRFIP2,NUAK1,CALB2,XYLT1,ETV5,FBXO2,MPP5,FAM81A,LTBP3,ZNF385B,LMNA,ZFYVE9,BTG3,PSMD1,SHC3,SLC16A6,ADAM15,VAT1,ABCD1,NTN4,SNX10,MDFI,SEMA3B,SMARCA2,ARAP2,CAPN6,COL7A1,TCF7,EPHA1,ATP1B1,C15orf39,ZFAND5,TYSND1,PRX,GABARAPL1,TMEM54,MAP2,S100A5,REEP4,TOB1,COL16A1 |
| 5.638e-04 | -7.48 | RUFFLE | MSigDB lists | RUFFLE | 31 | 10 | 17758 | 1761 |
ARAP3,S100A11,FGD6,EZR,CTTN,ARF6,BCAR1,MYO5A,S100A6,FGD1 |
| 5.638e-04 | -7.48 | ROZANOV_MMP14_TARGETS_SUBSET | MSigDB lists | ROZANOV_MMP14_TARGETS_SUBSET | 31 | 10 | 17758 | 1761 |
MDK,TIMP3,COL6A2,NR3C1,PLOD2,CALD1,COL6A1,MATN2,COL18A1,SULF2 |
| 5.638e-04 | -7.48 | MOSERLE_IFNA_RESPONSE | MSigDB lists | MOSERLE_IFNA_RESPONSE | 31 | 10 | 17758 | 1761 |
DDX58,MX1,USP18,HERC5,SAMD9,IFIT1,CD274,CMPK2,IFIT3,IFIH1 |
| 5.638e-04 | -7.48 | AMIT_SERUM_RESPONSE_40_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_40_MCF10A | 31 | 10 | 17758 | 1761 |
WEE1,TCTN2,NR4A1,ZFP36,FOSB,NR4A2,LGMN,CITED2,FOS,GM2A |
| 5.639e-04 | -7.48 | Alkaline_phosphatase_core | interpro domains | IPR017850 | 31 | 10 | 18293 | 1814 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 5.639e-04 | -7.48 | Alkaline_Pase-like_a/b/a | interpro domains | IPR017849 | 31 | 10 | 18293 | 1814 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 5.668e-04 | -7.48 | MODULE_129 | MSigDB lists | MODULE_129 | 214 | 37 | 17758 | 1761 |
WASF3,PAPSS2,DNAJB2,ITGA6,ETV5,BCL2L1,B4GALT4,TSPAN7,HDAC9,DOPEY2,TPST1,ALDH7A1,LGMN,ARL4D,TSPAN1,PTPRE,ZNF365,MX1,ING1,BCL9,SYNE2,GRIN1,IFIT3,LEPR,FZD7,DPYSL3,BCAR3,MDK,TRIM9,PIAS3,GPRC5B,P4HA2,SERPINI1,NRG1,ARSB,ST3GAL1,ARHGEF4 |
| 5.668e-04 | -7.48 | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | MSigDB lists | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | 214 | 37 | 17758 | 1761 |
LTBP1,ALDH6A1,IGFBP6,FOXM1,ST14,CTDSPL,SDC4,IL13RA1,BEX2,AIP,KIF5B,ALG13,SGK1,ECE1,CACNA1D,LGMN,GM2A,MED22,COG2,DRAP1,AMFR,CDC20,ARHGDIB,EIF2AK1,SAV1,MCFD2,ABR,NUCB1,HS6ST1,FGFR2,RND3,STK38,AMMECR1,MADD,SPINT2,ATP1B3,ARPC2 |
| 5.680e-04 | -7.47 | REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 42 | 12 | 17758 | 1761 |
CCND1,CCNE2,CDK5RAP1,DIRAS3,CDKN2C,CDKN1C,PTEN,HERC5,PKMYT1,CDKN2D,CDK5R1,CKS2 |
| 5.682e-04 | -7.47 | GRB7 events in ERBB2 signaling | REACTOME pathways | R-HSA-1306955 | 5 | 4 | 8202 | 867 |
ERBB2,NRG2,NRG1,ERBB3 |
| 5.716e-04 | -7.47 | HALLMARK_E2F_TARGETS | MSigDB lists | HALLMARK_E2F_TARGETS | 199 | 35 | 17758 | 1761 |
DLGAP5,SPC25,DEPDC1,CIT,PTTG1,TP53,CDCA8,BARD1,LBR,PSIP1,TOP2A,CDKN2C,WEE1,UBE2T,RANBP1,PLK4,TUBG1,CDKN1B,CKS2,HMMR,PLK1,SHMT1,CDC20,MYBL2,CDK1,PRDX4,DCK,AURKA,DONSON,HMGA1,CENPE,CCNB2,ESPL1,E2F8,MELK |
| 5.716e-04 | -7.47 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | 199 | 35 | 17758 | 1761 |
MYL9,SPRED1,CTHRC1,PCOLCE,PAPSS2,HSPG2,CD63,KCTD12,IL18,FAM198B,SLC1A3,TNS3,CTSC,CALD1,COL6A1,CYP1B1,DOCK4,CYP26B1,ASPM,TNS1,ANTXR1,IDH1,NFIB,ANKRD29,COL12A1,DPYSL3,FUCA1,PGF,GPRC5B,ACVRL1,RND3,FAM114A1,PLD1,LIFR,CYBRD1 |
| 5.720e-04 | -7.47 | V$ARNT_02 | MSigDB lists | V$ARNT_02 | 237 | 40 | 17758 | 1761 |
LAMP1,AVPI1,ARMCX3,CPEB4,ALDH6A1,FAM134A,PKN1,SNN,NUP62CL,VPS26A,CDKN2C,BHLHE41,FAM13B,BAX,SGK1,SNX16,MANF,EPB41L4B,ARMCX6,SIRT1,HPS3,SNTB2,CBX6,OGDHL,CDK5R1,PTPRF,GNAS,TIMM8A,NGFRAP1,HNRNPH2,KBTBD2,HOXA9,PRPS2,FAM117A,KLF11,HMGA1,GLA,C1orf43,MAFF,RNF146 |
| 5.729e-04 | -7.46 | KEGG_P53_SIGNALING_PATHWAY | MSigDB lists | KEGG_P53_SIGNALING_PATHWAY | 66 | 16 | 17758 | 1761 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,TP53I3,CDK1,FAS,CCND1,SESN3,PTEN,BAX,CCNB2 |
| 5.734e-04 | -7.46 | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS | 21 | 8 | 17758 | 1761 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH1A3,AOX1,ALDH7A1,ALDH3A2 |
| 5.734e-04 | -7.46 | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | MSigDB lists | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | 21 | 8 | 17758 | 1761 |
MBP,TRIM2,FGFR2,SLC39A8,LHX6,TLE1,HMGN3,BCL2L1 |
| 5.765e-04 | -7.46 | positive regulation of cell adhesion | biological process | GO:0045785 | 362 | 57 | 16441 | 1675 |
ADGRG1,IL15,ITGA6,HLA-E,RET,SDC4,ERBB2,IL18,CD274,FBLN1,EMP2,TNFSF9,EFNB1,HLA-A,ITGA3,CYR61,NPNT,IL6ST,BMP7,PIK3CA,IGFBP2,EPB41L4B,CITED2,WNT3A,SYK,RASGRP1,SOCS5,EPB41L5,HES1,CD55,RHOA,RIPK2,AKT1,FMN1,PIK3R1,UTRN,PRKCQ,EPHA1,YES1,STX3,CD83,PTPRJ,PLPP3,CSF1,TBX18,NR4A3,NOD2,TRIOBP,NRG1,ITGAV,PIEZO1,ARPC2,ICOSLG,JAK3,RAP1GAP,COL16A1,L1CAM |
| 5.820e-04 | -7.45 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 276 | 45 | 17758 | 1761 |
CCNE2,LTBP1,SCN5A,RUNX2,IL15RA,CPEB4,NUAK1,ZCCHC24,ETV5,ARHGEF40,TEAD3,NEO1,TFAP4,MGAT4A,FOSB,PDE4D,PIKFYVE,SPRY2,PPP6R1,CYP26B1,PMPCB,HES1,LCA5,KIF20A,NR3C1,SYBU,RAB38,ANLN,C3orf58,SP4,BSDC1,ABR,DZIP1L,NFIX,PITX2,HLF,BANK1,ATP1A1,FGFR2,MAP2,NR4A3,CLIP4,NR4A2,NFKBIZ,PKIA |
| 5.872e-04 | -7.44 | positive regulation of cysteine-type endopeptidase activity | biological process | GO:2001056 | 137 | 27 | 16441 | 1675 |
SIRT1,CASP3,NKX3-1,RHOA,ACVR1C,DAP,CASP9,RET,SLC11A2,BCAP31,FAS,TFAP4,CARD8,CTGF,CYR61,CTSC,NGFRAP1,DAPK1,BAX,ARRB1,CDKN1B,GPER1,WNT3A,EGLN3,MAP3K5,F2R,XDH |
| 5.876e-04 | -7.44 | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | 733 | 100 | 17758 | 1761 |
GNPDA1,CRYM,SNN,OAT,SLC20A1,KBTBD11,ERP29,BCAP31,CHPF,CALM2,APLP2,ATP6V0B,KIAA1107,EFR3A,DPYSL2,CABP1,REEP1,AKR1B1,ATRNL1,GOT1,CRY2,TECR,LGMN,BTBD3,MYRIP,ZNF365,GPX4,DOCK4,AKT1,DRAP1,NFE2L1,CBX6,KLK6,GLO1,MAN2A2,MSL1,SLC25A4,GPRC5B,DDOST,KCNK1,MADD,PNPLA6,SERPINI1,ITPKA,LTA4H,NRGN,CBX7,COBL,BIN1,LASP1,PINK1,ENO2,NUAK1,RUSC2,DNAJB2,PSMD10,CALM3,GTF3A,NCKAP1,TRIB2,TSPAN7,SAC3D1,SNTA1,CCDC92,CA2,RIMS3,CD9,SORL1,FAM102A,AHCY,NPTXR,GAD1,FADS2,RHOA,ALDH2,PSMB4,AMFR,STAT4,CALM1,FBXO9,NPC2,RASA1,GNAS,NUCB1,GABRD,SCG2,UTP14C,SPINT2,SLC4A3,TCEAL4,PGRMC1,PPM1H,DTX4,CABIN1,CTSA,MDH1,ARPC2,SHROOM2,RUSC1,ACOT7 |
| 5.900e-04 | -7.44 | response to steroid hormone | biological process | GO:0048545 | 402 | 62 | 16441 | 1675 |
GRN,ANXA3,CASP3,NKX3-1,NQO1,THRA,CALM3,ERBB2,PDGFB,ETS1,SDC1,CALM2,CCND1,TFAP4,CA2,CTGF,PTEN,BMP7,CST3,FOSB,BAX,ABCA2,CLDN4,CDKN1B,IGFBP2,GOT1,KLF9,CITED2,NR2C1,PAQR7,THRB,RHOA,CITED4,NR3C1,PTPRU,NR4A1,CALM1,CASP9,PPARA,ELK1,IDH1,FOS,FAS,SOCS3,FECH,MMP15,MDK,NCOA3,TIMP3,ATP1A1,NR1D2,MAP2,CTSV,NR4A3,AURKA,NR4A2,GPER1,HOXB13,ARSB,NR3C2,RARG,NR2C2 |
| 5.914e-04 | -7.43 | ABCA1 (ATP binding cassette subfamily A member 1) | protein interactions | 19 | 50 | 14 | 16036 | 1726 |
SNTA1,LMO7,PDLIM3,UGP2,ARHGEF11,LIMK1,SNTB2,AOX1,ERBB2IP,SNTB1,DLG3,PRKACA,TIAM1,RIMS2 |
| 5.914e-04 | -7.43 | HLA-E (major histocompatibility complex, class I, E) | protein interactions | 3133 | 50 | 14 | 16036 | 1726 |
MAN2A2,HLA-B,TCTN2,HLA-E,GALNT12,HLA-F,ITGA6,MADD,HLA-C,EPHB4,XRCC6BP1,MGAT5,HLA-A,TMEM131 |
| 5.921e-04 | -7.43 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | 177 | 32 | 17758 | 1761 |
GRN,CD99,CASP3,TXN,ENO2,LRRFIP2,DNAJC3,TAP1,NUCB2,CCNB1,NTAN1,PDIA4,UBE2J1,RPN2,MANF,FAIM,PDIA6,FAM69A,NFE2L3,SEC61B,ATP1B1,RAD17,FAS,PRDX4,FUCA1,ATP1A1,CORO1C,STK38,CTSA,SPCS3,ATP1B3,SLC27A3 |
| 5.921e-04 | -7.43 | RPS14_DN.V1_DN | MSigDB lists | RPS14_DN.V1_DN | 177 | 32 | 17758 | 1761 |
ARHGAP11A,PCOLCE,IL15RA,DEPDC1,DLGAP5,REPS2,LGR4,KIF23,ISOC2,EMP2,SPTB,EPCAM,B3GALNT1,SRR,TUBG1,TLN2,MYLIP,PLK1,SHMT1,KIF20A,PBK,CDC20,MYBL2,AGFG2,CENPE,FZD5,CCNB2,RAP1GAP,ESPL1,E2F8,CYBRD1,DOCK9 |
| 5.926e-04 | -7.43 | hair cycle process | biological process | GO:0022405 | 77 | 18 | 16441 | 1675 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,CTSV,DBI,HDAC1,CDH3,HOXC13 |
| 5.926e-04 | -7.43 | molting cycle process | biological process | GO:0022404 | 77 | 18 | 16441 | 1675 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,CTSV,DBI,HDAC1,CDH3,HOXC13 |
| 5.929e-04 | -7.43 | CHIN_BREAST_CANCER_COPY_NUMBER_UP | MSigDB lists | CHIN_BREAST_CANCER_COPY_NUMBER_UP | 26 | 9 | 17758 | 1761 |
CCND1,TOP2A,CD109,NCOA3,THRA,MYBL2,ERBB2,AURKA,CTTN |
| 5.934e-04 | -7.43 | S100B (S100 calcium binding protein B) | protein interactions | 6285 | 29 | 10 | 16036 | 1726 |
PGM1,TNIP1,S100A11,STK38,IQGAP1,S100A4,CALM1,TP53,S100A2,S100A6 |
| 5.938e-04 | -7.43 | S_TK_X | smart domains | SM00133 | 55 | 15 | 9131 | 997 |
RPS6KA2,ADRBK1,AKT1,CIT,RPS6KA1,STK38,SGK3,PRKG1,SGK1,PRKCQ,GRK6,PKN1,MAST4,PRKACA,ADRBK2 |
| 5.950e-04 | -7.43 | CUI_GLUCOSE_DEPRIVATION | MSigDB lists | CUI_GLUCOSE_DEPRIVATION | 60 | 15 | 17758 | 1761 |
GFPT1,TGIF1,PBK,DNAJC3,SGK3,FUT1,DNAJB11,PDIA3,GOT1,ANLN,PDIA6,CDK1,OCLN,ELF3,PDIA4 |
| 5.951e-04 | -7.43 | 4-hydroxyproline metabolic process | biological process | GO:0019471 | 12 | 6 | 16441 | 1675 |
PRODH,EGLN3,P4HA2,ERO1A,PRDX4,EGLN1 |
| 5.951e-04 | -7.43 | ureter development | biological process | GO:0072189 | 12 | 6 | 16441 | 1675 |
OSR1,SOX8,NPHP3,RET,SOX9,TBX18 |
| 5.951e-04 | -7.43 | branching involved in labyrinthine layer morphogenesis | biological process | GO:0060670 | 12 | 6 | 16441 | 1675 |
GRHL2,FZD5,FGFR2,ST14,SPINT2,SOCS3 |
| 5.961e-04 | -7.43 | CHYLA_CBFA2T3_TARGETS_UP | MSigDB lists | CHYLA_CBFA2T3_TARGETS_UP | 372 | 57 | 17758 | 1761 |
ANXA3,ARHGEF3,CCDC109B,S100A11,UBASH3B,TSC22D3,MTL5,PPFIBP2,MGST2,HOXB2,RASSF8,RALGPS2,CTSC,PLCG2,DRAM1,ATRNL1,VAT1,TNFRSF12A,ALPK1,NOTCH3,EGLN3,RAB27B,F2R,MAST4,TLE6,SUN2,GCA,PRODH,MCTP1,HPS3,KCNIP3,SEPT6,LPGAT1,CDA,TMEM144,PRKCQ,ARHGDIB,IDH1,SPNS3,CDK5R1,RASGRP2,ATP13A2,SOX13,CXXC4,SLCO4A1,PTPRJ,HPSE,PELI2,UACA,NRG1,EIF4EBP2,SH3BGRL2,PLOD3,SERPINB1,TMEM173,DOCK9,ABCG1 |
| 5.980e-04 | -7.42 | ZHU_CMV_8_HR_UP | MSigDB lists | ZHU_CMV_8_HR_UP | 48 | 13 | 17758 | 1761 |
PLA2G4A,MX1,CD55,B3GNT2,SP100,NR4A1,HLA-E,NR4A3,TRIM21,IRF2,IFIT1,LGMN,IFI6 |
| 5.980e-04 | -7.42 | BCAT_GDS748_UP | MSigDB lists | BCAT_GDS748_UP | 48 | 13 | 17758 | 1761 |
CA2,C3orf52,CASP9,AIM1,ABCB1,PKP2,KCTD12,PDE4D,GAD1,TP53I3,FZD7,FAH,GCNT1 |
| 5.993e-04 | -7.42 | GSE3982_MAC_VS_TH2_UP | MSigDB lists | GSE3982_MAC_VS_TH2_UP | 192 | 34 | 17758 | 1761 |
ACACB,SLC25A24,CEP70,FRMD4A,REPS2,GNPDA1,CAST,ETV5,NDRG2,ITPR2,PLXNA1,NTAN1,DNAJB9,LRRC6,PAPSS1,ACOX2,SPRY2,ALDH3A2,SOCS5,ENPP4,MMD,ACO1,SERTAD3,SLC11A2,IFIT3,STEAP1,FUCA1,PRKAG2,TIMP3,SWAP70,PRCP,RHOBTB2,FZD5,GOLGB1 |
| 5.993e-04 | -7.42 | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | 192 | 34 | 17758 | 1761 |
SLC25A24,ARMCX3,IQGAP1,SOX9,PDCL,PDIA3,COL4A5,NOTUM,CA8,DDR1,EMP2,SRPX2,ANO1,BCAP31,PDGFA,METTL7A,PCYOX1,TPST1,CCDC82,MX1,RHOA,FBLN5,PQLC3,ALCAM,PRIM1,HLF,POPDC3,COL13A1,NR1D2,ERAP1,LRRK1,PER3,NCAPG2,ABCG1 |
| 5.993e-04 | -7.42 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | 192 | 34 | 17758 | 1761 |
CD99,VANGL1,CAST,DGKQ,EFHD2,SYTL2,WWP2,PIK3AP1,CTSC,RGS3,PPP4R1,CNNM4,RASGEF1A,PDIA6,MYBL1,C12orf75,SYTL3,APOBEC3G,MBP,PQLC3,PRSS23,S100A4,SNTB2,MICB,SYNE2,DIAPH2,ARHGAP35,OPTN,FAS,WIPI1,PITPNA,PIEZO1,SLC27A3,STARD3NL |
| 5.993e-04 | -7.42 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 192 | 34 | 17758 | 1761 |
SPC25,FOXM1,TBC1D1,ERI2,C5orf30,PHLPP1,STIL,KCTD9,FANCI,BTG3,SIVA1,UBE2J1,RFX5,FAIM,TIMP2,PLSCR1,CDC20,C3orf52,EZR,GGH,LRRC1,ICMT,DCP2,FECH,TMEM164,PLCH1,FAM64A,CDK19,DBI,ATP1B3,CENPE,UBE2C,E2F8,ACOT7 |
| 5.993e-04 | -7.42 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | 192 | 34 | 17758 | 1761 |
CALB2,SOX9,ASAH1,AES,CARD10,TFAP4,RPS6KA2,ITGA3,ADRBK1,LYPD3,GATA2,SIVA1,BDH1,ADAM15,AHCY,ECE1,SYK,SUN2,PGM1,ALDH2,RIPK2,PTPN9,CASP9,PRKRA,H2AFV,ZFAND5,DCP2,SLC4A3,CSTF2,UNC5B,TRAF5,USF2,LTA4H,ACOT7 |
| 5.993e-04 | -7.42 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 192 | 34 | 17758 | 1761 |
CCNI,CMAS,ARMCX3,PPM1J,CAST,FTH1,NUCB2,DDR1,PDGFA,PHF7,ITGA3,TSPAN6,TOX2,MANF,PDIA6,CDKN2D,ALDH3A2,MED30,S100A6,CPD,SUSD3,SYPL1,TNIP1,FNDC3A,ALCAM,RANBP9,FRMD4B,AMZ2,CARHSP1,TWSG1,RAB11FIP1,NFKBIZ,GEM,GOLGB1 |
| 5.993e-04 | -7.42 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | 192 | 34 | 17758 | 1761 |
ARHGAP11A,CASP3,SPRED1,SPC25,SERPINE2,ST14,UBASH3B,BARD1,TMCC3,EPDR1,RCN1,CD109,EPCAM,TOP2A,RNF128,NPNT,PLK4,IQGAP3,C12orf75,GCNT1,LAMP2,PCGF5,LPGAT1,CORO2A,PBK,LITAF,FRMD4B,TWSG1,ZNF367,GNPTAB,INPP4B,NR4A2,CENPE,HOOK1 |
| 5.993e-04 | -7.42 | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDM_UP | 192 | 34 | 17758 | 1761 |
LASP1,ADD1,MRPS15,THRA,ARMC7,EFHD2,IL18,TGFBR1,FAM198B,SEPP1,LTBP3,LLGL2,SH3BP1,IL6ST,MITF,DLG1,TMEM51,DDX59,SYPL1,MBP,KIF20A,SLC37A1,ASPM,CORO2A,OXR1,CBX6,RNPEP,ANKRD10,NCOA3,RPL12,NGFRAP1,PLIN3,CCNB2,MYL12B |
| 5.999e-04 | -7.42 | ion binding | molecular function | GO:0043167 | 5991 | 669 | 16491 | 1673 |
ACACB,AK7,SLC25A13,RET,CACNA2D2,DHX8,LACTB2,SYTL4,CA8,BARD1,LTBP3,ZNF275,EPDR1,CALM2,DAPK2,WEE1,UBE2T,CABP1,CYP2S1,ALDH1A3,KLF3,TUBG1,CRY2,PIK3CD,ACOX2,RNF26,TIAM1,TIPARP,APOBEC3G,ERAP2,NWD1,SMARCA2,CDA,PRKAR2B,LOXL2,RNF19B,CYP4F3,ARF4,PIAS3,PGF,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,NOD2,AGFG2,ITPKA,ARF6,ALDH6A1,NUAK1,ITGA6,MTL5,RAB23,FAM21C,MERTK,HPCAL4,RABGGTA,MARCH8,GNS,MEGF8,NEK2,MAP3K9,CADPS2,ALPK1,ZMYM1,DGKG,MYLIP,MCCC2,KIF20A,SALL4,PCTP,SPTLC2,GNA11,DCP2,CYB5A,STK17A,DHX32,PTPRF,TIMM8A,ITPR1,S100A5,AURKA,STK39,DRP2,ZNF502,TMEM173,XDH,ADAMTS16,EGLN1,MTM1,RNF224,PAPSS2,GALNT12,ACTR8,TESK2,GRK6,PRKACA,REPS1,ZNF385B,RCN1,RNF220,CDH1,ENPP5,ACSL4,ARL4D,RAB27B,MYT1,SNX10,MX1,ENPP4,RIPK2,APOBEC3D,SEPT6,RAB38,XRCC6BP1,SNX12,ZNF618,PDLIM3,CDK19,AXL,TRABD2A,MAPK12,PKN1,NUCB2,SGPL1,DTX3L,DIRAS3,CTSC,ARSG,MGAT4A,FAM20B,ZFAND4,PLEKHF1,ECI2,ADAM15,MAPK11,NPTXR,S100A6,ACBD5,OPLAH,ADAMTS2,PLSCR1,RAPGEF2,GRIN1,UBE2A,AK4,BLVRA,NEURL1B,CRISPLD2,GALNT3,PLOD2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,CENPE,FHL1,CMPK2,OSR1,WDR45B,CYBRD1,ACOT7,TLL2,MYL9,UNKL,TRIM2,CNOT8,EPHA4,LMCD1,NENF,ITPR2,MGAT5B,HDAC6,PLS3,RPS6KA2,NPNT,MKRN3,PAPSS1,PAPL,PASK,ABCA2,DDX59,S100A13,ZNF462,PLK1,THRB,PCGF5,KCNIP3,ING1,MCTP1,CELSR2,ARFRP1,IDH1,ZBTB7B,CDK1,RHEB,DPYSL3,KDM4D,DZIP1L,TRIM9,PLCH1,KLF12,WIPI1,P4HA2,ZNF367,KLF11,PIK3C2B,PXDC1,MYL12B,RRAGD,PRKAA2,RUNX2,PARP12,LMTK3,ZCCHC24,RASA2,RAB6A,B4GALT4,FBLN1,UBE2Q2,IGF1R,GATA2,FRAS1,KIF13B,PIM1,PLCB2,ABCC1,CYP26B1,CHSY3,PCDH1,TESK1,MGAT4B,ZNF320,STRADB,EIF2AK1,PDK3,G2E3,CDK5R1,RASGRP2,MAPKAPK2,COL13A1,PHLPP2,ITGA7,PRPS2,P4HA3,NLRC5,ZDHHC7,LTBP2,ZDBF2,PLD1,RNF146,UGP2,P3H2,CTDSPL,TP53,ERBB2,CYP26A1,SYTL2,LMO4,LHX6,SRR,BCL6,ZDHHC23,PLK4,CDH3,VAT1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,SULF2,CTH,CPD,SIRT1,CLCN3,TIMP2,AKT1,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,DUOX1,IDE,ATP1A1,MMP17,PTK7,STK38,ADAMTS14,ANXA9,SYT13,AIFM3,LTA4H,ZNF701,MAN2B2,ZMAT1,PINK1,PACSIN2,TOR4A,CDH22,GNE,ERI2,SELL,GTF3A,CRABP2,NRP2,PPP2R3A,ZDHHC21,FOXP2,CDK16,ALPP,GTF2F2,UBE2J1,SGK1,TRIM21,BUB1,ABCD1,KLF9,SYK,ATP2B1,FAH,FBLN5,RHOA,NR3C1,AMFR,PPARA,PRICKLE1,RNPEP,DGKE,FAT4,ZNF214,PPP2R3C,UBE2C,PTGES,HIPK3,ZBTB33,HSPG2,ATP8A1,TAP1,CAMK1D,PJA2,OAT,NCS1,CYP1A1,ZNF823,CTGF,STIM1,PRICKLE3,ZFP36,STEAP2,AOX1,PIK3CA,SNX16,MARCH2,PACSIN1,ZBTB18,SMYD5,METAP2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,GALNT7,MCFD2,ZFAND5,TP53I3,POR,PRIM1,GDE1,PLK2,GNPTAB,PTER,NKD1,PRDM5,BMP1,DHTKD1,TRAF5,FGD1,DDX58,CDK17,CALB2,DGKQ,KIF23,SLC1A3,S100A2,PRRG4,BMP2K,MECOM,C9orf69,ITGA3,CYR61,SNX18,ZNRF2,PRKG1,ADCK2,DAPK1,CACNA1D,PIKFYVE,MAST4,SYTL3,RIMS2,PRODH,PMPCB,ZNF84,MFI2,ADCK3,TBC1D8B,CALM1,AMER1,PIP4K2C,ATP8B3,EPHA1,JADE2,ANTXR1,STX3,DGKH,MMP15,PRKAG2,DCK,CSNK1G1,MATN2,AGBL5,FGD6,PCDH19,CDK18,NR4A2,MAP3K5,IFIH1,NRBP1,EHD1,PLA2G4A,REPS2,S100A11,NLRX1,THRA,RPS6KA1,IQGAP1,ATP2C2,FTH1,RNF182,AIFM2,DDR1,CYP39A1,ZFYVE9,APOBEC3B,APLP2,NOV,ZNF75D,ACAP2,TRANK1,DAB2IP,EPHB4,PDE4D,NR2C1,MYO5B,SEC23A,PANK1,UTRN,KIF1C,PRKCQ,SLC11A2,PKMYT1,PYGO1,RAD17,ATP1B1,ITPR3,ATP10D,SP4,ZNF469,NIN,EPHA10,AMZ2,JAK1,STK26,NGFRAP1,ZNF704,EFCAB14,KLF5,MLKL,NR3C2,PCOLCE,ATP9A,ARL4C,EFHD2,APOBEC3H,CYB561,DNAH3,RNF128,PHF7,PTEN,SGK3,ATP8B1,ERBB3,CNOT6L,TRIM62,SHMT1,ARHGEF28,ARAP2,LONRF3,ZC3H11A,FURIN,ZKSCAN2,YES1,AIF1L,KIF11,ARSK,CPTP,CDK5RAP1,NUCB1,TIMP3,ACADSB,FGFR2,ABCB1,RYK,PGM2L1,ERAP1,LRRK1,ARSB,MELK,ESYT2,NMRK1,LTBP1,CAMKK1,VARS2,DNER,TRIM68,HTR1D,ABCD4,CHPF,ZFYVE16,RAB15,ZCCHC12,IMPAD1,SIVA1,TRPC1,RAB20,RP2,MYH14,MYRIP,RASGRP1,SP5,CYP1B1,NLRP4,ATL1,TRIM8,ROR1,STK17B,ADRBK2,CXXC4,MAN2A2,MDK,NEIL1,ZNF114,ZNF165,SP6,ADIPOR1,NRGN,CPPED1,CAPN1,NR2C2,LASP1,ARAP3,ZNF395,SERPINE2,BVES,PEX6,ABCG2,CALM3,TEC,PHLPP1,ZNF432,CA2,LIMCH1,ZRANB1,GAD1,CCDC88A,SNX7,GYLTL1B,PDE5A,RNF113A,PDIK1L,NUBP1,STEAP1,AMDHD1,FECH,GNAS,NUDT16,CGREF1,RHOBTB2,ALPK3,YOD1,EGFL7,JAK3,RARG,SNX30,KLF7,LMO7,SLC25A24,COL18A1,MORC4,MRAS,OSR2,ZNF687,SETDB2,CYP4F11,KIF14,ZDHHC12,FABP6,GOT1,ECE1,SCYL3,CHP1,SEPHS1,MAP3K3,ZNF525,GCA,GLO1,MAP3K6,ARHGAP35,JADE1,PEX2,OVOL1,CYP2U1,ABCA1,GLIS3,FBLIM1,ANXA3,ENO2,CIT,LRP4,TGFBR1,HDAC9,IRF2BPL,KIF5B,TOP2A,MLPH,TAF1B,ADRBK1,BMP7,GALNS,MYO5A,PHF20L1,PGM1,RAB3B,NR4A1,GCLC,RC3H2,OGDHL,MBNL3,NADK2,RUNX3,ENDOD1,SWAP70,RND3,TRIM69,RAP2C,DTX4,GEM,PLOD3,ZMIZ1,L1CAM,ABCG1 |
| 6.032e-04 | -7.41 | PHOSPHORYLATION | MSigDB lists | PHOSPHORYLATION | 308 | 49 | 17758 | 1761 |
PRKAA2,CDK17,PINK1,NF2,RET,ERBB2,TESK2,TGFBR1,PKN1,TRIB2,MERTK,BARD1,CCND1,DAPK2,CDKN2C,IGF1R,CDK16,IL31RA,SGK3,PRKG1,MAP3K9,PLK4,DAPK1,CDKN1B,SGK1,ERBB3,PIM1,F2R,CDKN2D,CCDC88A,MAP3K3,AKT1,PIK3R1,STRADB,EIF2AK1,RAD17,MAP3K6,STK17B,PRDX4,STK17A,MAPKAPK2,ACVRL1,STK38,LIMK1,NR4A3,AURKA,JAK3,HIPK3,MAPK12 |
| 6.051e-04 | -7.41 | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | MSigDB lists | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | 54 | 14 | 17758 | 1761 |
TOP2A,DLGAP5,ZNF84,UBE2T,CYR61,ASPM,PBK,AURKA,BUB1,ANLN,CCNB1,UBE2C,CDK1,FANCI |
| 6.051e-04 | -7.41 | KEGG_INOSITOL_PHOSPHATE_METABOLISM | MSigDB lists | KEGG_INOSITOL_PHOSPHATE_METABOLISM | 54 | 14 | 17758 | 1761 |
PLCG1,ALDH6A1,PTEN,PLCG2,INPP4B,PIK3CA,PIP4K2C,PIK3C2B,ISYNA1,PIK3CD,MINPP1,PIKFYVE,ITPKA,PLCB2 |
| 6.063e-04 | -7.41 | MACROMOLECULE_LOCALIZATION | MSigDB lists | MACROMOLECULE_LOCALIZATION | 230 | 39 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,ERP29,BARD1,AIP,ZFYVE9,APPBP2,PDIA4,ATG4A,ZFYVE16,CARD8,AP1M2,CDH1,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,KDELR1,ATG4D,MDFI,AKT1,COG2,STRADB,ICMT,OPTN,KLHL2,SCG2,SHROOM3,NOD2,CTSA,LTBP2,SHROOM2,ABCA1,ABCG1 |
| 6.080e-04 | -7.41 | CD151 (CD151 molecule (Raph blood group)) | protein interactions | 977 | 8 | 5 | 16036 | 1726 |
GRAMD1C,ITGA3,PTGFRN,CD82,ITGA6 |
| 6.111e-04 | -7.40 | ITGB1 (integrin beta 1) | protein interactions | 3688 | 98 | 22 | 16036 | 1726 |
TIMP2,LGALS3,NF2,HSPG2,CD63,PLAUR,CD82,ITGA6,EPS8,FBXO2,PDIA3,TGOLN2,FBXO6,FBLN1,DAG1,RANBP9,LGALS3BP,ITGA3,IGF1R,ITGA7,CD9,ITGAV |
| 6.115e-04 | -7.40 | Tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 24812 | 5 | 4 | 16036 | 1726 |
PDIA3,HLA-B,TAPBP,HLA-A |
| 6.115e-04 | -7.40 | VWA1 (von Willebrand factor A domain containing 1) | protein interactions | 64856 | 5 | 4 | 16036 | 1726 |
VWA1,RCN1,HSPG2,PDIA6 |
| 6.115e-04 | -7.40 | Espl1 (extra spindle pole bodies 1, separase) | protein interactions | 105988 | 5 | 4 | 16036 | 1726 |
CCNB1,CDK1,ESPL1,PTTG1 |
| 6.115e-04 | -7.40 | DERL3 (derlin 3) | protein interactions | 91319 | 5 | 4 | 16036 | 1726 |
MFI2,SERPINA1,AMFR,UBE2J1 |
| 6.173e-04 | -7.39 | Antigen processing-Cross presentation | REACTOME pathways | R-HSA-1236975 | 81 | 19 | 8202 | 867 |
MRC2,SEC61B,PSMB4,PSME2,HLA-E,HLA-F,TAP1,PSMD10,PDIA3,PSME1,PSMA4,HLA-A,CTSL,HLA-B,TAPBP,PSMD1,CTSV,HLA-C,ITGAV |
| 6.193e-04 | -7.39 | MEL18_DN.V1_DN | MSigDB lists | MEL18_DN.V1_DN | 141 | 27 | 17758 | 1761 |
COL9A3,TRIM2,ALDH6A1,CDH22,ZCCHC24,SH3BGRL,ESRP1,PKP2,PDE5A,NDRG2,CRABP2,SEPP1,FOS,STK17B,FRMD4B,DIRAS3,SCNN1A,CA2,FAM46A,PTER,TFAP2A,SERPINI1,PIK3C2B,HOXB13,IFIT1,TSPAN1,IFI6 |
| 6.212e-04 | -7.38 | cellular response to type I interferon | biological process | GO:0071357 | 71 | 17 | 16441 | 1675 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,IRF2,IRF7,HLA-C,OAS3,IFIT1,IFI6 |
| 6.212e-04 | -7.38 | type I interferon signaling pathway | biological process | GO:0060337 | 71 | 17 | 16441 | 1675 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,IRF2,IRF7,IFIT1,OAS3,HLA-C,IFI6 |
| 6.232e-04 | -7.38 | V$ISRE_01 | MSigDB lists | V$ISRE_01 | 238 | 40 | 17758 | 1761 |
DDX58,SORBS1,MACC1,HLA-F,ETV5,CACNA2D2,ERBB2,PRKACA,DTX3L,CDKN2C,ADD3,NPNT,RRBP1,DUSP10,ADAM15,TRIM21,CDH3,IRF2,HLA-C,TECR,SCN2A,ARMCX6,PCGF5,KCNIP3,RIPK2,USP18,SH3BGRL,NUB1,SLC11A2,IFIT3,COL12A1,OPTN,CXXC4,TAPBP,MAP2,AMMECR1,OVOL1,FAM117A,IFIH1,JARID2 |
| 6.238e-04 | -7.38 | GROSS_HYPOXIA_VIA_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_DN | 106 | 22 | 17758 | 1761 |
CPD,LMO7,TGIF1,ENO2,DAP,VWA1,IL18,MERTK,FOS,KLHL2,PGF,ACAP2,CTGF,CYR61,ZFP36,NFKBIA,SH3BP4,PRKCDBP,SGK1,SPRY2,S100A13,CAPN1 |
| 6.238e-04 | -7.38 | LE_EGR2_TARGETS_DN | MSigDB lists | LE_EGR2_TARGETS_DN | 106 | 22 | 17758 | 1761 |
UGT8,MBP,CD55,PIK3R1,UTRN,FTH1,EMP2,CMTM6,MAPK8IP1,PRX,KCNK1,FAAH,TMEM30A,FUT8,ABCB1,ABCA2,CD9,LIMCH1,NR4A2,TIPARP,CPEB2,SEMA3B |
| 6.271e-04 | -7.37 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | 185 | 33 | 17758 | 1761 |
LASP1,TM2D2,AVPI1,LGALS3,GNPDA1,UBASH3B,TSC22D3,HEXB,C5orf30,TGFBR1,S100A2,BCAP31,ADCK2,SGK1,BRI3,TNFRSF12A,SPRY2,WBP5,TGIF1,C6orf1,LONRF3,MFI2,PLEKHO1,LHFPL2,SNX12,STX3,BCAR3,SCARB2,CORO1C,LIMK1,NRBP1,RRAGD,ABCG1 |
| 6.271e-04 | -7.37 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | 185 | 33 | 17758 | 1761 |
CASP3,MRPS15,NDC80,ISOC2,NANS,SAC3D1,RCN1,APOBEC3B,TOP2A,SS18,TYMP,PSMD1,CTSC,BHLHE41,RRBP1,PAPSS1,FUT8,LMAN1,KDELR1,FAM69A,PPIF,GFPT1,LAMP2,SHMT1,CDC20,GGH,KIF11,SLC25A4,DNM1L,WIPI1,ERAP1,CCNB2,NRBP1 |
| 6.271e-04 | -7.37 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | 185 | 33 | 17758 | 1761 |
EPAS1,CYB561,IL13RA1,TRIB2,DDR1,H1FX,APLP2,FAM46A,AOX1,TPST1,SORL1,TSPAN13,SCN3A,XKR8,GCNT1,RASGRF1,CXorf57,UTRN,SESN1,DOCK5,EDNRA,GALNT3,NEIL1,SCG2,CDK19,PRCP,MMP17,PLK2,DTX4,ABCB1,PIK3C2B,NRGN,KLF7 |
| 6.271e-04 | -7.37 | YAGI_AML_FAB_MARKERS | MSigDB lists | YAGI_AML_FAB_MARKERS | 185 | 33 | 17758 | 1761 |
SERPINE2,CAST,ITGA6,CACNA2D2,MORF4L2,TRIB2,FANCI,SNTA1,TYMP,GATA2,FAM20B,SORL1,TRPC1,NCAM1,RAB27B,F2R,MAST4,GAD1,TGIF1,ORAI2,TIMP2,DRAP1,STAT4,ACO1,GGH,TIMP3,ALDH5A1,PLOD2,HOXA9,NR4A3,NR4A2,SERPINI1,PKIA |
| 6.282e-04 | -7.37 | WIERENGA_STAT5A_TARGETS_UP | MSigDB lists | WIERENGA_STAT5A_TARGETS_UP | 200 | 35 | 17758 | 1761 |
CDKN1C,CALB2,TGFBR1,CTSZ,FBXO6,DHRS3,PHLDA1,IL18R1,NCS1,SLC9A7,SNTA1,CA2,GATA2,A4GALT,VASN,COL6A1,DAPK1,PIM1,RASGEF1A,CKAP4,LAMP3,AK4,TP53INP2,STK17B,C3orf58,GABARAPL1,CD83,SLC25A4,P4HA2,GNPTAB,SH3BP4,PGM2L1,RAP1GAP,F2RL1,ABCA1 |
| 6.283e-04 | -7.37 | positive regulation of immune response | biological process | GO:0050778 | 582 | 84 | 16441 | 1675 |
LAMP1,IL15,INPP5D,RPS6KA1,PSME2,IL27RA,PSME1,ITPR2,PRKACA,CACNB4,CALM2,PSMD1,RPS6KA2,ELMO2,IL6ST,PLCG2,PIK3CA,PDE4D,PIK3CD,SCARA3,LGMN,SMAGP,RASGRP1,SIRT1,CD55,RIPK2,TNIP1,ITCH,CR2,PRKCQ,CD40,ITPR3,DUSP4,PLCG1,PTPRJ,GPRC5B,LIMK1,NOD2,IRF7,F2RL1,DDX58,THEMIS2,HLA-E,CALM3,PSMD10,BTN3A1,NCKAP1,TEC,HLA-A,PTEN,PIK3AP1,BAX,MAPK11,CNPY3,SYK,SOCS5,KLK5,PLSCR1,PSMB4,MICB,CALM1,PIK3R1,RGCC,YES1,ELK1,FOS,BCAR1,PSMA4,GPLD1,CTSL,MAPKAPK2,HLA-B,PVRL2,PELI2,NFKBIA,ITPR1,NR4A3,NLRC5,KLK7,FZD5,ARPC2,JAK3,IFIH1,TMEM173 |
| 6.326e-04 | -7.37 | developmental maturation | biological process | GO:0021700 | 195 | 35 | 16441 | 1675 |
RUNX2,CDKN1C,EPAS1,IL15,CD63,RET,CNTNAP2,CCNB1,PRKACA,RPS6KA2,PTEN,GATA2,LHX6,NTN4,FARP2,REC8,CLCN3,HES1,RHOA,ANO6,GRIN1,RAB38,DAG1,CDK5R1,BFSP1,FAT4,ACVRL1,SEMA4D,AXL,PTBP3,NR4A2,HOXB13,GDF11,SOX8,FZD5 |
| 6.335e-04 | -7.36 | transport | biological process | GO:0006810 | 3697 | 430 | 16441 | 1675 |
LAMP1,SLC35D2,ACACB,ADD1,TSC22D3,SLC25A13,ATP8A1,CACNA2D2,TAP1,TGOLN2,SYTL4,SLC20A1,SLC9A7,NCS1,CALM2,PQLC2,AP1M2,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,PIK3CD,TINAGL1,TMEM37,MARCH2,PACSIN1,XKR8,LAMP2,ORAI2,SLC35C1,PRKAR2B,KIF13A,LOXL2,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,ARF4,ENPP1,PLCG1,SLC25A4,DNM1L,LIMK1,GNPTAB,ATP7B,TRAF3IP1,NOD2,SARAF,ARF6,F2RL1,NXT2,SCN5A,MRC2,NFKBIE,GGA1,RAB23,SLC25A27,NDUFA4,SLC36A4,SLC1A3,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,DOPEY2,SNX18,RIMS3,ATP5H,RPL39,SLC16A6,RANBP1,PCYOX1,SORL1,CADPS2,PANX2,CACNA1D,PIKFYVE,SYTL3,NUP85,C9orf72,PPP6R1,RIMS2,TRAK2,PMPCB,KCNJ12,SLC37A1,KIF20A,MFI2,CALM1,ANO6,ERO1A,NPC2,ATP8B3,PCTP,SFXN5,STX3,CYB5A,SLCO4A1,CACHD1,AP1AR,GABRD,SCARB2,PRKAG2,SLC4A4,TIMM8A,CSNK1G1,ITPR1,SLC4A3,NDE1,ARPC2,PLIN3,HOOK1,NRBP1,NUP58,XDH,EHD1,PLA2G4A,MFSD3,MTM1,CCDC109B,SLC2A4,TRIP10,RALBP1,ATP2C2,C5orf30,FTH1,BCL2L1,CD274,MVB12B,PRKACA,DDR1,TMPRSS4,ZFYVE9,APPBP2,CCND1,SCNN1A,CDKN1B,CNNM4,IFIT1,ACSL4,ARL4D,RAB27B,SNX10,TMEM9,SCN3A,ATG4D,MYO5B,SEC23A,SEC61B,COG2,FZD4,KIF1C,HTATIP2,SLC11A2,ATP1B1,RAB38,ITPR3,SNX12,ATP10D,DDOST,CORO1C,SLC9A6,AXL,SLC27A1,RGS14,SLC25A30,DENND5B,TTC8,TCAF1,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,CYB561,ANO9,SLC25A43,LGALS3BP,PDIA4,SLC25A36,CXCL16,ADD3,SLC27A6,CTSC,SGK3,CD9,BAX,KLC3,ATP8B1,SLC44A2,WWP1,SLC16A5,TPCN1,S100A6,NCOA2,ACBD5,LCA5,ZC3H11A,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,FURIN,PARP4,YES1,NEURL1B,CPTP,GPLD1,MAMDC4,RPL12,FGFR2,RAB11FIP2,SYT7,DBI,ABCB1,NR4A3,GRIN2D,ITGAV,ARSB,USF2,SLC25A38,CYBRD1,ESYT2,EXPH5,ILDR1,CRYM,CPT2,ARFGEF1,F11R,ITPR2,HDAC6,CACNB4,NUP62CL,PDGFB,ERP29,SLC8B1,DNER,TMC1,SH3KBP1,ABCD4,SUSD2,ZFYVE16,RAB15,DPYSL2,SLC44A1,ABCA2,TRPC1,RAB20,RP2,CTTN,SLC39A10,SCARA3,ANO4,TRAM1,MYRIP,S100A13,RASGRP1,KCNIP3,CELSR2,STAU2,EZR,ARFRP1,ADRBK2,OPTN,EDNRA,TRIM9,KCNMB4,KCNK1,UEVLD,WIPI1,RAB11FIP1,PIEZO1,PCSK5,PRKAA2,GRN,LASP1,ARAP3,PEX6,BVES,FXYD3,SLC22A31,ABCG2,CALM3,RAB6A,NCKAP1,ANO1,CA2,RINL,GATA2,FRAS1,KIF13B,KCNN4,EXOC8,FXYD5,SELK,GAD1,SLC12A2,SNX7,ABCC1,KDELR1,BTN3A2,STRADB,SCRIB,EIF2AK1,MFSD7,STEAP1,GNAS,MAPKAPK2,SLC6A6,TMEM30A,MFSD2A,NFKBIA,SLC2A6,SH3BP4,ZDHHC7,CTSA,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,JAK3,TOB1,APOL2,NIPA1,SNX30,DYNLRB1,SLC25A24,SORBS1,UPF3B,TP53,SLC7A2,EMP2,BCAP31,SYTL2,TTC21B,PDGFA,SLC25A48,ATP6V0B,SVBP,ZDHHC12,KIF14,PLCG2,FABP6,BCL6,ZDHHC23,RPN2,SCN2A,LMAN1,F2R,GM2A,CHP1,PPIF,CLCN3,AKT1,SLC39A8,OSTM1,ACO1,DAG1,ATP13A2,TAPBP,ALDH5A1,ATP1A1,PEX2,SPTBN5,SYT13,ABCA1,ARFGEF3,BIN1,ANXA3,MFSD14B,SORT1,GOLIM4,PACSIN2,CD63,LRP4,GABRG2,CRABP2,AIP,VPS26A,HMGXB4,SLC9A2,ZDHHC21,M6PR,TMEM63A,KIF5B,ADORA1,ADRBK1,MLPH,LLGL2,CDK16,RRBP1,SGK1,ABCD1,SYK,ATP2B1,MYO5A,HES1,SYPL1,RAB3B,FBLN5,PPARA,PRICKLE1,COL7A1,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,ARRB1,MCUR1,SPCS3,CEP41,NDFIP1,TBC1D4,ARHGEF9,RAB3IL1,ABCG1,SNPH |
| 6.335e-04 | -7.36 | LENAOUR_DENDRITIC_CELL_MATURATION_UP | MSigDB lists | LENAOUR_DENDRITIC_CELL_MATURATION_UP | 113 | 23 | 17758 | 1761 |
MMD,AES,SLC11A2,GDF15,HMGN3,ATP1B1,CRABP2,TRIB2,OAT,LGALS3BP,CYB5A,ARF4,CD83,CDH1,CTSC,CSF1,SPINT2,NR4A3,SERPINB6,CITED2,RAP1GAP,ACOT7,ABCG1 |
| 6.351e-04 | -7.36 | negative regulation of cell growth | biological process | GO:0030308 | 166 | 31 | 16441 | 1675 |
GAS2L1,SIRT1,SEMA6B,SMARCA2,ING1,NF2,SERPINE2,SERTAD3,CDA,TP53,CDK5R1,JADE1,CDKN2C,ENPP1,NOV,PTPRJ,SEMA4D,ACVRL1,CGREF1,SH3BP4,BCL6,ADAM15,CDKN1B,ADIPOR1,SEMA3G,FHL1,WNT3A,CDKN2D,SEMA3A,OSGIN1,SEMA3B |
| 6.429e-04 | -7.35 | HALLMARK_CHOLESTEROL_HOMEOSTASIS | MSigDB lists | HALLMARK_CHOLESTEROL_HOMEOSTASIS | 73 | 17 | 17758 | 1761 |
FADS2,LGALS3,PLSCR1,S100A11,GUSB,PLAUR,FBXO6,PDK3,ALCAM,CXCL16,ABCA2,CD9,TNFRSF12A,MAL2,LGMN,CPEB2,SEMA3B |
| 6.435e-04 | -7.35 | spindle | cellular component | GO:0005819 | 283 | 46 | 17570 | 1756 |
DLGAP5,CKAP2,RPS6KA1,POC1B,CDCA8,CALM3,KIF23,CCNB1,SAC3D1,CALM2,RPS6KA2,FRY,KIF14,NEK2,TUBG1,CTTN,NUP85,PLK1,AKT1,KIF20A,CAPN6,SEPT6,ASPM,CALM1,CDC20,CCSAP,PARP4,NUSAP1,SLC25A5,KIF11,CDK1,NIN,CEP162,PLEKHG6,FAM83D,AGBL5,FAM110C,AURKA,PPP2R3C,CENPE,GEM,NDE1,RGS14,WDR62,HSPB1,ESPL1 |
| 6.441e-04 | -7.35 | actin binding | molecular function | GO:0003779 | 389 | 60 | 16491 | 1673 |
WASF3,LASP1,SORBS1,NF2,SSH1,ADD1,TMSB15A,EPS8,HDAC6,SPTB,EPS8L2,TMSB15B,PLS3,SNTA1,ADD3,SCNN1A,CALD1,POF1B,FXYD5,ESPN,DIXDC1,LIMCH1,RP2,MYH14,TLN2,MYRIP,NEB,MYO5A,CCDC88A,MYO5B,SSH3,FMN1,SNTB2,S100A4,CORO2A,SYNE2,UTRN,DIAPH2,EZR,TNS1,ANLN,SNTB1,AIF1L,ANTXR1,DAG1,KLHL2,PLEKHH2,SHROOM3,CORO1C,TRIOBP,NOD2,CLMN,SPTBN5,TMOD2,ARPC2,SHROOM2,HOOK1,AFAP1,COBL,RUSC1 |
| 6.504e-04 | -7.34 | regulation of epithelial cell proliferation | biological process | GO:0050678 | 278 | 46 | 16441 | 1675 |
GRN,SCN5A,NKX3-1,CDKN1C,SOX9,ERBB2,TGFBR1,OSR2,VASH1,PDGFB,SIX4,NRP2,CD109,CCND1,PTEN,DLG1,BAX,CDH3,CDKN1B,DAB2IP,TWIST1,TACSTD2,EPB41L4B,MYDGF,KLF9,IQGAP3,ETV4,SIRT1,AKT1,NR4A1,RGCC,RUNX3,SAV1,NFIB,FZD7,FGFR2,SCG2,ACVRL1,CTSV,TBX18,PEX2,NR4A3,NOD2,EGFL7,OSR1,XDH |
| 6.505e-04 | -7.34 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 341 | 53 | 17758 | 1761 |
CCNE2,SPC25,TCTN2,ETV5,CTDSPL,PTTG1,ARL4C,KIF23,TDRKH,NUF2,TGFBR1,ISYNA1,PLXNA1,PHLDA1,EMP2,FAM46C,LBR,NCS1,PDGFA,WEE1,E2F7,UBE2T,SPIN4,KCNN4,ALDH1A3,RANBP1,PLK4,BUB1,ECE1,PIM1,CITED2,PTPRE,ETV4,TIPARP,SUN2,FADS2,ZWINT,ADCK3,PBK,MYBL2,EZR,PKMYT1,FOS,RASGRP2,SLCO4A1,SLC6A6,TIMP3,ZNF367,PELI2,ARRB1,E2F8,MELK,EHD1 |
| 6.534e-04 | -7.33 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 929 | 123 | 17570 | 1756 |
PLA2G4A,IL15RA,DNAJC3,XYLT1,PDIA5,TAP1,ITPR2,MGST2,PJA2,LPIN3,CYP39A1,BCAP31,CYP26A1,ABCD4,CDS1,CYP1A1,CYP4F11,STIM1,CYP2S1,XYLT2,REEP1,DLG1,RPN2,MARCH2,NOTCH3,ACSL4,TECR,LMAN1,SCARA3,PDIA6,TRAM1,RASGRP1,ERAP2,CYP1B1,MX1,ATL1,SEC23A,EVA1A,SEC61B,C3orf52,SYNE2,NFE2L1,PKMYT1,DNAJB14,ITPR3,MCFD2,ICMT,PTGFRN,TRIQK,CASP4,ATP10D,POR,CYP4F3,RHEB,TAPBP,DDOST,AGPAT2,DOLPP1,SLC9A6,WFS1,PNPLA6,SARAF,CYP2U1,PIEZO1,REEP4,NR3C2,SORT1,HLA-E,FXYD3,HLA-F,DHRS3,LBR,HLA-A,DNAJB9,SGPL1,FLRT3,ALG13,RRBP1,SUCO,BAX,UBE2J1,TMBIM6,SGK1,SELK,HLA-C,FAR2,ALDH3A2,CKAP4,KDELR1,FAM69A,CYP26B1,FADS2,RHOA,LPGAT1,PLAUR,AMFR,ELOVL3,EIF5A2,ERO1A,FURIN,EMC2,TXNDC11,SPTLC2,MAPK8IP1,CYB5A,HLA-B,FAAH,PLOD2,PLPP3,MFSD2A,ITPR1,PGRMC1,ERAP1,GPER1,SPCS3,PLD1,PLOD3,MAP3K5,APOL2,PTGES,TMEM173,ABCG1,ESYT2 |
| 6.539e-04 | -7.33 | negative regulation of mitotic cell cycle | biological process | GO:0045930 | 225 | 39 | 16441 | 1675 |
HECA,NKX3-1,PSME2,CTDSPL,PTTG1,TP53,PSMD10,PSME1,BCL2L1,FANCI,IER3,CCND1,TOP2A,E2F7,BTG3,PSMD1,PTEN,DACT1,BMP7,DLG1,CDKN1B,BUB1,CTDSP2,PLK1,TIMP2,ZWINT,PSMB4,CDC20,RGCC,SCRIB,RAD17,PSMA4,CDK1,JADE1,FGFR2,PLK2,OVOL1,FHL1,UBE2C |
| 6.547e-04 | -7.33 | MODULE_93 | MSigDB lists | MODULE_93 | 178 | 32 | 17758 | 1761 |
ALDH6A1,NQO1,BLVRB,PDIA3,NDUFA4,COX6C,SPR,DHRS3,ERP29,CYP26A1,PDIA4,CYP1A1,SIVA1,ALDH1A3,AOX1,AKR1B1,ALDH7A1,ACOX2,ALDH3A2,GPX4,CYP1B1,FADS2,IDH1,TP53I3,PRDX4,ALDH3B1,ALDH5A1,ACADSB,DHRS2,MDH1,PLOD3,XDH |
| 6.547e-04 | -7.33 | V$CART1_01 | MSigDB lists | V$CART1_01 | 208 | 36 | 17758 | 1761 |
HOXB7,KLHL13,CALB2,RAB6A,SPTB,TEAD3,ZDHHC21,ARHGEF10L,CDKN2C,FOXP2,ANKS1B,CALD1,LMO4,ELF5,BCL6,CLDN4,ATP8B1,TACSTD2,MYT1,RIMS2,SEPHS1,ACBD5,PDGFC,SMARCA2,PLEKHA6,SERTAD4,C1GALT1C1,ROR1,ITPR3,NFIX,ACADSB,PELI2,ARRB1,MAL2,REEP4,HIPK3 |
| 6.547e-04 | -7.33 | MARKEY_RB1_ACUTE_LOF_UP | MSigDB lists | MARKEY_RB1_ACUTE_LOF_UP | 208 | 36 | 17758 | 1761 |
GRN,PSME2,IQGAP1,TAP1,NDRG2,CTSZ,CRABP2,TNFSF9,LGALS3BP,SGPL1,SP100,FAM13B,IFIT1,ACSL4,LGMN,SGCB,USP18,SAT1,PLEKHO1,UBE2A,IFIT3,FNDC3A,CASP4,SOCS3,TAPBP,MID1IP1,SH3BGRL2,IRF7,CMPK2,IFIH1,HIPK3,ABCA1,PCSK5,ABCG1,EGLN1,XDH |
| 6.570e-04 | -7.33 | forebrain development | biological process | GO:0030900 | 356 | 56 | 16441 | 1675 |
ANXA3,EMX1,CASP3,SCN5A,NF2,ADGRG1,CNTNAP2,STIL,ETS1,PHLDA1,MECOM,TTC21B,FOXP2,APLP2,CDH1,PTEN,GATA2,DPYSL2,KIF14,LHX6,ALDH1A3,BAX,PRKG1,DAB2IP,DIXDC1,NOTCH3,ZBTB18,WNT3A,BTBD3,HES1,RHOA,TACC1,ASPM,RAPGEF2,GRIN1,TFAP2C,BBS2,NFIB,CDK5R1,ARHGAP35,PITX2,MDK,FAT4,FGFR2,TWSG1,PHLPP2,AXL,DBI,NR4A3,RYK,NR4A2,NRG1,WDR62,NDE1,NRGN,SEMA3A |
| 6.585e-04 | -7.33 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | 156 | 29 | 17758 | 1761 |
PLA2G4A,LAMP2,ANXA3,ALDH2,PCDH1,ENO2,NUAK1,EPS8,ARL4C,ARHGDIB,LOXL2,ATP1B1,TP53I3,SRPX2,GLCE,MECOM,IER3,PGF,RCN1,UAP1,CTSC,PLOD2,AXL,COL6A1,TACSTD2,LTBP2,ITGAV,ECE1,PKIA |
| 6.596e-04 | -7.32 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | 193 | 34 | 17758 | 1761 |
TXN,NFKBIE,NQO1,TRIP10,CD63,SDC4,FTH1,BCAP31,LMNA,IER3,ZFYVE16,KCNN4,MITF,TUBG1,MANF,PIM1,GM2A,GPX4,ABCC1,CYP1B1,LAMP3,PPIF,DOCK4,TNIP1,STAT4,PIP4K2C,AK4,DUSP4,ALCAM,SLCO4A1,ETS2,ATP1B3,ST3GAL1,MAFF |
| 6.596e-04 | -7.32 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | 193 | 34 | 17758 | 1761 |
GAS2L1,GRN,EXPH5,TTC39B,TRIP10,CKAP2,NENF,PLXNA1,CRABP2,DPP8,EPDR1,IER3,PQLC2,SPIN4,OPN3,DAPK1,SNX16,PIM1,C12orf75,FARP2,PCGF5,SHMT1,NEURL1B,CD83,TMEM164,SLC6A6,TIMP3,GDE1,PLOD2,P4HA2,SLC2A6,NR4A3,PPP2R3C,GLA |
| 6.596e-04 | -7.32 | WANG_CISPLATIN_RESPONSE_AND_XPC_UP | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_UP | 193 | 34 | 17758 | 1761 |
ANXA3,CKAP2,FXYD3,ASB9,COL18A1,COL4A5,MGST2,TNFSF9,LBR,CDH1,CTSC,KIF14,CD9,CLDN4,IGFBP2,MANF,CKS2,SEMA3B,HES1,FADS2,FIGNL1,NPC2,KIF11,CYP4F3,CDK1,PTPRF,SERPINA1,DCK,DBI,SPINT2,AURKA,ZNF502,UBE2C,JARID2 |
| 6.596e-04 | -7.32 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | 193 | 34 | 17758 | 1761 |
RPS6KA1,KCTD12,PSME1,PRKACA,FAM46C,B4GALNT1,CYP1A1,RGS3,ZFP36,CD9,MDFIC,MYH14,CLIP2,GM2A,CRTAP,GUSB,NR4A1,LITAF,C1GALT1C1,COL7A1,SNX12,C3orf58,MAPKAPK2,HLA-B,TAPBP,ITGA7,NMI,HDAC1,NR4A2,JAK3,NRGN,NDFIP1,PTGES,XDH |
| 6.596e-04 | -7.32 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | 193 | 34 | 17758 | 1761 |
CIT,ATP2C2,ASB9,MORC4,KIF23,SYTL4,FAM101B,IL18R1,IL17RB,PQLC2,RPS6KA2,PIM1,CTTN,HLA-C,EPB41L4B,PHKA2,TLE6,GM2A,S100A6,CPD,ALDH2,LITAF,CASP4,RASGRP2,GABARAPL1,CMTM7,PIAS3,PVRL2,BMP1,RELL1,GEM,TMEM159,NRGN,PPP2R2D |
| 6.596e-04 | -7.32 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 193 | 34 | 17758 | 1761 |
PRSS8,TXN,S100A11,AASS,PSME2,TSC22D3,MORF4L2,SPTB,IER3,TYMP,PSMD1,CDH1,ANKRD12,TRIM21,IFIT1,MANF,CYP1B1,PLSCR1,RAPGEF2,MICB,SAT1,PTGER4,AK4,RNF19B,STK17A,CD83,ENDOD1,PLCH1,SERPINA1,ACVRL1,NFKBIA,DBI,NR4A3,IFI6 |
| 6.608e-04 | -7.32 | SPIRA_SMOKERS_LUNG_CANCER_UP | MSigDB lists | SPIRA_SMOKERS_LUNG_CANCER_UP | 37 | 11 | 17758 | 1761 |
PLA2G4A,ANXA3,CD55,SERPINA1,SLC4A4,SLC39A8,SOX9,UBE2J1,FOS,TRAM1,TOB1 |
| 6.616e-04 | -7.32 | cell-substrate adherens junction | cellular component | GO:0005924 | 395 | 60 | 17570 | 1756 |
CD99,LMO7,LASP1,FBLIM1,SORBS1,PACSIN2,MRC2,ADD1,HSPG2,ITGA6,IQGAP1,SDC4,PDIA3,KIF23,NCKAP1,SDC1,SH3KBP1,TNS3,ITGA3,CDH1,FLRT3,CD9,IRF2,DIXDC1,CTTN,TLN2,CHP1,EPB41L5,RHOA,SNTB2,PLAUR,SYNE2,EZR,TNS1,YES1,SNTB1,AIF1L,ALCAM,BCAR1,DAG1,ARHGAP24,SCARB2,RPL12,JAK1,RND3,PVRL2,ITGA7,LIMK1,PTK7,CORO1C,TRIOBP,ITGAV,FHL1,HMGA1,ARPC2,ARF6,HSPB1,AFAP1,L1CAM,CAPN1 |
| 6.638e-04 | -7.32 | CEACAM21 (carcinoembryonic antigen-related cell adhesion molecule 21) | protein interactions | 90273 | 45 | 13 | 16036 | 1726 |
PTPRF,PODXL2,FAT4,PVRL2,PTK7,HLA-F,FUT8,EPHA4,EXOC8,RYK,TNFSF9,EFNB1,DAG1 |
| 6.701e-04 | -7.31 | immune response-activating signal transduction | biological process | GO:0002757 | 388 | 60 | 16441 | 1675 |
DDX58,THEMIS2,INPP5D,RPS6KA1,PSME2,CALM3,BTN3A1,PSMD10,PSME1,TEC,ITPR2,NCKAP1,PRKACA,CACNB4,CALM2,RPS6KA2,PSMD1,PIK3AP1,ELMO2,PTEN,PLCG2,BAX,PIK3CA,MAPK11,PIK3CD,PDE4D,SCARA3,LGMN,CNPY3,SYK,TNIP1,PSMB4,RIPK2,ITCH,MICB,CALM1,PIK3R1,CR2,PRKCQ,YES1,ELK1,ITPR3,DUSP4,FOS,BCAR1,PSMA4,GPLD1,CTSL,MAPKAPK2,PLCG1,PTPRJ,LIMK1,PELI2,NFKBIA,ITPR1,NR4A3,NOD2,IRF7,ARPC2,IFIH1 |
| 6.747e-04 | -7.30 | Frs2-mediated activation | REACTOME pathways | R-HSA-170968 | 233 | 41 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 6.775e-04 | -7.30 | V$OCT1_07 | MSigDB lists | V$OCT1_07 | 149 | 28 | 17758 | 1761 |
NUDT6,MBP,PLEKHA6,FRMD4A,GRHL2,SCOC,CPEB4,FZD4,SERTAD4,SLC25A13,LYRM1,LDB2,NEO1,HDAC9,NFIX,CCND1,FOXP2,ADD3,RALGPS2,FGFR2,CSNK1G1,XYLT2,LMO4,TMOD2,DIXDC1,MYT1,BTBD3,TOB1 |
| 6.818e-04 | -7.29 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 171 | 31 | 17758 | 1761 |
B3GNT2,TXN,IL15RA,RIPK2,PLAUR,RAPGEF2,IL18,CD274,SAV1,CCNB1,CDK1,CD83,SOCS3,IER3,OTUD1,E2F7,ETS2,UAP1,PIK3AP1,MFSD2A,FJX1,NFKBIA,DRAM1,UBE2J1,SELK,NFKBIZ,PLD1,GEM,MAFF,ATP2B1,LAMP3 |
| 6.821e-04 | -7.29 | neural tube formation | biological process | GO:0001841 | 104 | 22 | 16441 | 1675 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 6.827e-04 | -7.29 | temporal_lobe | COSMIC cancer mutations | temporal_lobe | 107 | 22 | 17775 | 1757 |
ENPP4,NF2,AKT1,PTPRU,RASA2,SYNE2,RET,TP53,SPATA13,ERBB2,MORF4L2,IDH1,GNA11,GNAS,ZFYVE16,CDKN2C,PTEN,FGFR2,MKRN3,PIK3CA,PIKFYVE,GOLGB1 |
| 6.877e-04 | -7.28 | lipid translocation | biological process | GO:0034204 | 21 | 8 | 16441 | 1675 |
KCNN4,ATP8A1,ATP9A,TMEM30A,ATP8B1,ATP8B3,ABCA1,ATP10D |
| 6.884e-04 | -7.28 | FCERI mediated Ca+2 mobilization | REACTOME pathways | R-HSA-2871809 | 30 | 10 | 8202 | 867 |
CALM2,PLCG1,PLCG2,ITPR1,CALM1,CALM3,ITPR2,TEC,ITPR3,SYK |
| 6.899e-04 | -7.28 | Inositol phosphate metabolism | REACTOME pathways | R-HSA-1483249 | 46 | 13 | 8202 | 867 |
CALM2,PLCH1,PLCG1,PTEN,INPP5D,PLCG2,CALM1,INPP4B,CALM3,ISYNA1,MINPP1,ITPKA,PLCB2 |
| 6.913e-04 | -7.28 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | 186 | 33 | 17758 | 1761 |
SORT1,CCDC109B,FAM134A,PPFIBP2,SELL,KCTD12,NUCB2,NTAN1,KBTBD11,MERTK,BCAP31,LGALS3BP,GNS,APLP2,TYMP,OPN3,DRAM1,CITED2,SPRY2,SYK,PDGFC,MPP1,DIAPH2,TCF7,FOS,IDH1,TP53I3,SERPINA1,SPINT2,CTSA,LTBP2,ST3GAL1,ABCG1 |
| 6.913e-04 | -7.28 | ERB2_UP.V1_DN | MSigDB lists | ERB2_UP.V1_DN | 186 | 33 | 17758 | 1761 |
DDX58,ANXA3,COL9A3,DEPDC1,CALB2,ERI2,SLC7A2,HERC6,STIL,BTG3,SS18,ADD3,IGF1R,ALG13,PLK4,ANKRD12,ATP8B1,IFIT1,MYBL1,TIAM1,RASGRP1,CYP26B1,ZNF84,LPGAT1,PRKAR2B,DNAJB14,STK17A,LRIG1,MATN2,IRF7,CENPE,IFIH1,IFI6 |
| 6.913e-04 | -7.28 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 186 | 33 | 17758 | 1761 |
ZNF395,CNOT8,INPP5D,XYLT1,TGOLN2,SNN,HERC6,LBR,SCML1,ADD3,PTEN,FRYL,AIM1,OPN3,ADCK2,FXYD5,ATP8B1,SORL1,TSPAN13,SLC39A10,RCAN3,GM2A,MBP,ARAP2,FIGNL1,NUB1,MBNL3,GYLTL1B,CR2,RASGRP2,PLEKHG1,RAB11FIP1,ST3GAL1 |
| 6.913e-04 | -7.28 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | 186 | 33 | 17758 | 1761 |
EXPH5,LRRFIP2,IGFBP6,HLA-F,FTH1,MNS1,HDAC9,RCN1,DOPEY2,RPS6KA2,PHF7,RNF128,RGS3,LMO4,TAGLN2,CTTN,S100A13,CKAP4,DOCK4,CPD,TGIF1,ALDH2,TIMP2,SAT1,NFE2L1,IFIT3,SAV1,DAG1,TRIM9,SERPINI1,NRG1,ADIPOR1,ATP1B3 |
| 6.964e-04 | -7.27 | DOUGLAS_BMI1_TARGETS_DN | MSigDB lists | DOUGLAS_BMI1_TARGETS_DN | 302 | 48 | 17758 | 1761 |
UNKL,CPEB4,FAM199X,GNPDA1,BVES,BTN3A1,TDRKH,HERC6,PARM1,FZD6,EPDR1,M6PR,TMEM63A,WEE1,SESN3,SP100,ZDHHC12,SGK1,IFIT1,OAS3,ACSL4,SUN2,CLCN3,APOBEC3D,TACC1,RAPGEF2,SLC39A8,PANK1,PIP4K2C,TMEM144,VEZT,IFIT3,ATP10D,DCP2,RASA1,OPTN,PITX2,TMEM164,ENPP1,RBM47,H1F0,RAP2C,FGD6,CLIP4,PGM2L1,NFKBIZ,SEMA3A,IFI6 |
| 6.977e-04 | -7.27 | RHO GTPases activate CIT | REACTOME pathways | R-HSA-5625900 | 16 | 7 | 8202 | 867 |
MYL9,CDKN1B,MYH14,RHOA,CIT,MYL12B,KIF14 |
| 6.977e-04 | -7.27 | Polo-like kinase mediated events | REACTOME pathways | R-HSA-156711 | 16 | 7 | 8202 | 867 |
PLK1,WEE1,PKMYT1,CCNB1,FOXM1,CCNB2,MYBL2 |
| 6.979e-04 | -7.27 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 100 | 21 | 17758 | 1761 |
NFE2L3,NFKBIE,FOXM1,SOX9,MYBL2,TFAP2C,HTATIP2,RUNX3,NFIB,RBL1,LMO4,NMI,ELF5,TLE1,KLF5,KLF11,HMGA1,MYBL1,ETV7,E2F8,MDFI |
| 7.003e-04 | -7.26 | GNF2_STAT6 | MSigDB lists | GNF2_STAT6 | 80 | 18 | 17758 | 1761 |
IQGAP1,HLA-E,HLA-F,INPP5D,SELL,ARHGDIB,GRK6,CASP4,CMTM6,HLA-A,HLA-B,TAPBP,ACAP2,FXYD5,OSTF1,HLA-C,ARF6,ARPC2 |
| 7.009e-04 | -7.26 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | 224 | 38 | 17758 | 1761 |
ACACB,TNRC6C,CEP70,FRMD4A,ETV5,VARS2,GTF3A,ISYNA1,LBR,H1FX,NEO1,MECOM,B3GALNT1,UBE2T,LMO4,FAM13B,SCARA3,PHKA2,SPRY2,GPR161,SEPHS1,GFPT1,OPLAH,ALDH2,PSMB4,FZD7,ARHGEF26,MAN2A2,GNAS,SHROOM3,ABHD12,ZNF704,AGBL5,FAM117A,MDH1,TRAF5,GLCCI1,LIFR |
| 7.009e-04 | -7.26 | V$SOX9_B1 | MSigDB lists | V$SOX9_B1 | 224 | 38 | 17758 | 1761 |
HSPG2,HOXB7,KLHL13,TSC22D3,TRIB2,SYTL2,NEO1,HDAC9,CCDC92,TOP2A,RCN1,WEE1,SH3BP1,DPYSL2,RGS3,FLRT3,LHX6,KLF3,CDKN1B,NCAM1,MYT1,SEPHS1,MAP3K3,DPYSL5,DOCK4,TRIM8,FBLN5,MBP,NR4A1,NFIB,ARF4,G2E3,NFIX,ARHGEF19,FGFR2,PELI2,TLE1,ZNF502 |
| 7.013e-04 | -7.26 | IL-6 Signaling Pathway | WikiPathways | WP364 | 99 | 23 | 4455 | 516 |
CASP3,AKT1,INPP5D,PIK3R1,CASP9,ERBB2,TEC,CD40,FOS,PPP2R3A,CDK5R1,SOCS3,MAPKAPK2,PLCG1,RPS6KA2,JAK1,PPP2R5A,IL6ST,SGK1,HDAC1,ERBB3,HSPB1,GAB1 |
| 7.068e-04 | -7.25 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 310 | 50 | 16441 | 1675 |
PRKAA2,PINK1,TNRC6C,DLGAP5,SCOC,CNOT8,DNAJB2,PSME2,PSMD10,PSME1,TRIB2,CCNB1,BCAP31,PSMD1,RNF128,CTSC,PTEN,ZFP36,BAX,PLEKHF1,TRIM21,DAB2IP,TWIST1,SOCS5,PLK1,SIRT1,TRIM8,AKT1,PSMB4,GCLC,NUB1,CDC20,PIP4K2C,FURIN,PPARA,PRICKLE1,EZR,TP53INP2,RNF19B,PSMA4,CDK1,PLIN5,GPLD1,IRS2,PLK2,SH3BP4,AURKA,UBE2C,TOB1,ESPL1 |
| 7.070e-04 | -7.25 | negative regulation of cytoskeleton organization | biological process | GO:0051494 | 111 | 23 | 16441 | 1675 |
GAS2L1,ADD1,CKAP2,EPS8,ARFGEF1,CCNF,CCNB1,HDAC6,NUBP1,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,TBCD,NEK2,TRIOBP,AURKA,TMOD2,TACSTD2,ESPN,SPTBN5,SHROOM2 |
| 7.072e-04 | -7.25 | JAK1 (Janus kinase 1) | protein interactions | 3716 | 99 | 22 | 16036 | 1726 |
PLA2G4A,SIRT1,PLAUR,INPP5D,PIK3R1,ERBB2,AGO4,IL27RA,TEC,ELF3,SOCS3,IRS2,DTX3L,MDK,PLCG1,IGF1R,JAK1,IL6ST,PLCG2,ARRB1,JAK3,SYK |
| 7.140e-04 | -7.24 | immune system development | biological process | GO:0002520 | 601 | 86 | 16441 | 1675 |
CASP3,ADD1,HOXB7,EPAS1,IL15,THRA,RET,TP53,CACNB4,PDGFB,TNFSF9,SPTB,ARTN,LMO4,PLCG2,MITF,IL31RA,TMEM143,BCL6,RTKN2,PIK3CD,SNX10,TIPARP,SPEF2,OSTM1,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,HOXA9,AXL,PTBP3,DHTKD1,F2RL1,RUNX2,TNRC6C,CDKN1C,BVES,TGFBR1,PKN1,HERC6,MERTK,IL18R1,SIX4,HDAC9,MECOM,SGPL1,TOP2A,CD109,GATA2,BAX,CITED2,WNT3A,SYK,FARP2,HES1,RHOA,RC3H2,PIK3R1,TTC7A,RUNX3,EIF2AK1,FOXL1,FAS,PITX2,FECH,ONECUT1,SWAP70,FGFR2,TWSG1,DHRS2,CSF1,PPP2R3C,LRRK1,FZD5,JAK3,CCNB2,SLC25A38,MELK,JARID2 |
| 7.144e-04 | -7.24 | telencephalon development | biological process | GO:0021537 | 226 | 39 | 16441 | 1675 |
ANXA3,EMX1,CASP3,SCN5A,NF2,ADGRG1,CNTNAP2,FOXP2,PTEN,DPYSL2,KIF14,LHX6,ALDH1A3,BAX,DAB2IP,DIXDC1,ZBTB18,WNT3A,BTBD3,HES1,RHOA,TACC1,ASPM,GRIN1,TFAP2C,BBS2,NFIB,CDK5R1,MDK,FAT4,PHLPP2,DBI,RYK,NR4A3,NRG1,NDE1,WDR62,NRGN,SEMA3A |
| 7.176e-04 | -7.24 | regulation of metabolic process | biological process | GO:0019222 | 6593 | 733 | 16441 | 1675 |
ACACB,DNAJC3,HEXB,RET,FBXO2,NRG2,IL18,MORF4L2,BARD1,CARD10,GRM5,ZNF275,CALM2,CDKN2C,DAPK2,PSMD1,CABP1,KLF3,CRY2,PIK3CD,TIAM1,TIPARP,APOBEC3G,SMARCA2,TNIP1,CDA,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,RNF19B,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,TRAF3IP1,NOD2,AGFG2,HDAC1,SERPINB6,HSPB1,E2F8,GAB1,HOXC13,GGA1,NUAK1,ITGA6,SOX9,RAB23,GPSM2,LMNA,ELF3,MARCH8,TFAP4,PAIP2B,MEGF8,FAM13B,RANBP1,NEK2,MAP3K9,MYDGF,NCAM1,MYLIP,NUP85,PPP6R1,SALL4,STAT4,PYM1,MYBL2,ELK1,NPHP3,TP53INP2,PSMA4,DCP2,PLIN5,STK17A,NCOA3,ETS2,SEMA4D,SETD3,ITPR1,AURKA,STK39,GDF11,SERPINB1,ZNF502,NUP58,TMEM173,XDH,EGLN1,DOCK9,ARHGAP11A,GRHL2,NQO1,INPP5D,ACTR8,PTTG1,RGS20,MGST2,PRKACA,APC2,CCND1,ST5,CDH1,SP100,SH3BP1,DACT1,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,CAMSAP3,RIPK2,APOBEC3D,FZD4,HTATIP2,CDCA2,GTF2A2,SNX12,ZNF618,NFIX,IRS2,CORO1C,WFS1,SIPA1L1,PLEKHG1,RGS14,MAPK12,NKX3-1,TNRC6C,CKAP2,ESRP1,SDC4,HABP4,CTSZ,PKN1,ETS1,GSTP1,ARHGEF40,SRPX2,TIPRL,HOXB2,NEO1,CTNNBIP1,DIRAS3,ITGB8,CTSC,CST3,BAX,PLEKHF1,TMBIM6,WWP1,MAPK11,MED22,CRTAP,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,PITX2,NR1D2,ACVRL1,NR4A3,ITGAV,CENPE,HMGA1,OSR1,USF2,SIGIRR,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,HDAC6,PDGFB,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,MITF,ELF5,PASK,ABCA2,DUSP10,MYBL1,ZNF462,PLK1,THRB,PCGF5,CD55,KCNIP3,CELSR2,CITED4,CBX6,NFE2L1,EZR,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,KDM4D,PLEKHG6,KLF12,ZNF367,HOXA9,PRKCDBP,KLF11,MAFF,RRAGD,PRKAA2,RUNX2,LMTK3,DNAJB2,FXYD3,RASA2,UBASH3B,PDCL,HES2,FBLN1,DAZAP1,IGF1R,RINL,GATA2,TBCD,MDFIC,PIM1,WNT3A,PLCB2,RGMB,ZNF320,SPATA13,STRADB,SCRIB,EIF2AK1,TCF7,PDK3,CDK5R1,FOXD2,RASGRP2,MAPKAPK2,CSF1,NLRC5,ATP1B3,IFI6,USP43,AVPI1,NF2,HOXB7,UPF3B,FOXM1,CTDSPL,TP53,ERBB2,LPIN3,STIL,EMP2,BCAP31,SYTL2,IER3,RAD23A,TTC21B,PDGFA,LMO4,PLCG2,LHX6,BCL6,CDH3,NOTCH3,TMEM64,OAS3,EGLN3,CTDSP2,GM2A,DVL2,CTH,SIRT1,PPIF,CLCN3,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,RBL1,MMP17,STK38,EFNA5,IRF7,ZNF701,ARFGEF3,PINK1,CPEB4,MACC1,CD63,DAP,PSMD10,GTF3A,GDF15,HMGN3,NKRF,CRABP2,AIP,PARM1,FZD6,SH2D4A,PPP2R3A,ZDHHC21,CD109,FOXP2,GTF2F2,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,KLF9,SYK,TLE6,WBP5,NFE2L3,HES1,FBLN5,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,MAPK8IP1,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,PPP2R3C,NDFIP1,TBC1D4,UBE2C,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,TXN,PPP4R4,SSH1,LGR4,TSC22D3,PSME1,CAMK1D,CCNB1,ZNF823,CTGF,ZFP36,RGS3,IL31RA,FOSB,SERINC2,PIK3CA,IRF2,RCAN3,ZBTB18,ACVR1C,PBK,CASP9,AGO4,PIF1,SAV1,LDB2,POR,ARHGEF26,AHRR,HLF,PLK2,NKD1,PRDM5,EIF4EBP2,NFKBIZ,SERPINI1,F2RL1,TRAF5,LZTS1,FGD1,DDX58,CDKN1C,SCOC,TBC1D1,DGKQ,PSIP1,BMP2K,MECOM,ITGA3,RALGPS2,CYR61,SNX18,BHLHE41,PPP4R1,PRKG1,DAPK1,SORL1,PIKFYVE,GPR161,RIMS2,TRAK2,SOCS5,EPB41L5,GFPT1,MMD,ZNF84,MFI2,TBC1D8B,CALM1,PIP4K2C,NPC2,EPHA1,NFIB,RASA1,FAS,MMP15,AP1AR,PRKAG2,PELI2,TCEAL4,FAM83D,FGD6,SFMBT1,CABIN1,NR4A2,PER3,MAP3K5,SPRED1,FOXO6,DLGAP5,ARMCX3,S100A11,THRA,RPS6KA1,IQGAP1,CAST,RALBP1,BCL2L1,EPS8L2,APLP2,NOV,ZNF75D,ACAP2,FAM46A,CDKN1B,DAB2IP,PDE4D,IFIT1,MED30,NR2C1,DOCK4,FOXJ2,DRAP1,PRKCQ,SLC11A2,ATP1B1,PKMYT1,PYGO1,RAD17,ITPR3,H2AFV,SP4,FZD7,ZNF469,PRDM11,PPP2R5A,JAK1,STK26,NGFRAP1,SLC27A1,KLF5,NRG1,NR3C2,CBX7,DENND5B,ARHGEF3,PCOLCE,DEPDC1,HERC5,PBX3,APOBEC3H,SPR,FGF19,TEAD3,SIX4,WWP2,SCML1,SNTA1,E2F7,RNF128,PTEN,SGK3,DRAM1,ATP8B1,ERBB3,CITED2,CNOT6L,SPRY2,TRIM62,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARAP2,ARHGEF28,FURIN,ZKSCAN2,YES1,GRTP1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,GRIN2D,GPER1,LRRK1,FZD5,CPEB2,ESPL1,RGMA,JARID2,EMX1,CASP3,CRYM,CAMKK1,VARS2,ERP29,DENND2D,EPCAM,ARHGEF10L,ZFYVE16,SIPA1L2,HSF2,GRHL1,ZCCHC12,ARHGEF37,SIVA1,PHTF1,DLG1,RP2,CTTN,SLC39A10,RASGRP1,SP5,CYP1B1,TRIM8,ASCL5,ITCH,USP18,ARHGDIB,TYSND1,EDNRA,MDK,NEIL1,ARHGEF19,ZNF114,GPRC5B,MADD,ZNF165,CAB39,ADIPOR1,SP6,GLA,RAP1GAP,NR2C2,PIFO,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,CALM3,TEC,PHLPP1,ZNF432,SUCO,C10orf54,RFX5,LRIF1,ETV7,ALS2CL,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,RANBP9,SOX13,FECH,GNAS,BCAR3,NUDT16,ONECUT1,PLPP3,NFKBIA,SH3BP4,CTSA,YOD1,JAK3,TOB1,RARG,KLF7,PROM2,GAS2L1,CCNE2,SORBS1,IL15,PSME2,HDAC11,IL27RA,TDRKH,OSR2,ARHGEF16,SS18,SVBP,ZNF687,SETDB2,FRYL,KIF14,TWIST1,ECE1,EPB41L4B,F2R,FRS3,CKS2,CHP1,MAP3K3,ZNF525,GLO1,ERBB2IP,DUSP4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,JADE1,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,PPP2R2D,ABCA1,GLIS3,ANXA3,GCLM,SORT1,ARHGEF11,LRP4,MIER3,TGFBR1,AES,TRIB2,SBF1,HMGXB4,HDAC9,IRF2BPL,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,IQGAP3,NR4A1,GCLC,RC3H2,RGCC,MBNL3,RUNX3,TCEAL8,LEPR,FOXL1,ARHGAP24,SWAP70,PRCP,SPINT2,RAP2C,ARRB1,HOXB13,ZMIZ1,SOX8,AHR,RAB3IL1,ABCG1 |
| 7.176e-04 | -7.24 | GNF2_INPP5D | MSigDB lists | GNF2_INPP5D | 43 | 12 | 17758 | 1761 |
HLA-B,TAPBP,HLA-E,INPP5D,HLA-F,TAP1,PSME1,ARHGDIB,HLA-C,GRK6,ARF6,HLA-A |
| 7.176e-04 | -7.24 | ZHAN_MULTIPLE_MYELOMA_HP_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_DN | 43 | 12 | 17758 | 1761 |
S100A4,CST3,OPN3,TMBIM6,EIF4EBP2,IL27RA,TAGLN2,NTAN1,PDIA6,ST3GAL1,PKIA,SGPL1 |
| 7.179e-04 | -7.24 | tubulin binding | molecular function | GO:0015631 | 265 | 44 | 16491 | 1673 |
GAS2L1,PIFO,ARL4C,KIF23,HDAC6,APC2,KIF5B,STIM1,DPYSL2,KIF13B,KIF14,TBCD,REEP1,KLC3,DIXDC1,CLIP2,CCDC88A,CHP1,PLK1,DPYSL5,CAMSAP3,SUN2,KIFC2,KIF20A,CAPN6,FMN1,SYBU,STMN3,EZR,KIF1C,KIF13A,NUSAP1,KIF11,DAG1,GABARAPL1,MAP2,TRAF3IP1,FAM83D,AGBL5,FAM110C,CENPE,RGS14,NDE1,REEP4 |
| 7.205e-04 | -7.24 | CYTOSKELETAL_PART | MSigDB lists | CYTOSKELETAL_PART | 232 | 39 | 17758 | 1761 |
MYL9,LASP1,BMF,SORBS1,DLGAP5,IQGAP1,KIF23,HDAC6,SPTB,APPBP2,SAC3D1,ATG4A,TOP2A,KIF5B,CNTRL,CABP1,TBCD,NEK2,TUBG1,BUB1,ESPN,CLIP2,ATG4D,PLK1,PCGF5,CDC20,EZR,ANLN,KIF11,RANBP9,CDK1,NIN,MAP2,AURKA,CEP41,NDE1,ARPC2,SHROOM2,ESPL1 |
| 7.226e-04 | -7.23 | negative regulation of response to external stimulus | biological process | GO:0032102 | 264 | 44 | 16441 | 1675 |
SIGIRR,SEMA6B,PINK1,SERPINE2,NLRX1,UBASH3B,EPHA4,TP53,NENF,PDGFB,ETS1,GSTP1,IER3,CD109,PDGFA,NOV,ADORA1,PTEN,TSPAN6,PRKG1,DUSP10,SEMA3G,IFIT1,WNT3A,SEMA3B,PSMB4,ITCH,PBK,PLAUR,MICB,GRIN1,PTGER4,PPARA,F12,BBS2,ABR,SOCS3,SEMA4D,TRAF3IP1,NOD2,GPER1,NDFIP1,SEMA3A,LZTS1 |
| 7.250e-04 | -7.23 | NS-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | NS-carcinoma-squamous_cell_carcinoma | 17 | 7 | 17775 | 1757 |
GNAS,ERBB2,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 7.253e-04 | -7.23 | GSE3982_MAST_CELL_VS_BCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_UP | 194 | 34 | 17758 | 1761 |
RMND5A,PCOLCE,SORBS1,CACNA2D2,CCDC68,HES2,REPS1,LMNA,NOV,PSMD1,OSBPL3,PAPSS1,DAPK1,DRAM1,DUSP10,CTTN,SPRY2,CORO2A,PIK3R1,EIF5A2,YES1,PCTP,IDH1,LEPR,GABARAPL1,SOX13,FRMD4B,DCTN6,P4HA2,BMP1,PPM1H,ARRB1,ANXA9,RNF146 |
| 7.253e-04 | -7.23 | GSE27786_NKTCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_DN | 194 | 34 | 17758 | 1761 |
CASP3,CPEB4,CPT2,IQGAP1,NDC80,SLC36A4,VPS26A,ELF3,KIF5B,ZNF687,RAB20,ACOX2,IQGAP3,TRAK2,CYP1B1,AMOTL2,HMMR,SUN2,KIF20A,LPGAT1,STRADB,ARHGEF26,OPTN,CMTM7,KLHL2,BCAR3,MID1IP1,WIPI1,PELI2,NETO2,EGFL7,GDF11,NCAPG2,NIPA1 |
| 7.253e-04 | -7.23 | GSE360_CTRL_VS_L_DONOVANI_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_DN | 194 | 34 | 17758 | 1761 |
KLK10,TXN,IL15RA,ENO2,NRP2,IER3,TYMP,LYPD3,AKR1B1,ATP8B1,APOBEC3G,SLC16A5,LAMP3,MX1,RASGRF1,MBP,SLC39A8,ACO1,GRIN1,LITAF,CYB5A,CD83,IRS2,SCARB2,ETS2,FGFR2,NFKBIA,WDR62,UNC5B,JAK3,AHR,NR3C2,ACOT7,EHD1 |
| 7.253e-04 | -7.23 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | 194 | 34 | 17758 | 1761 |
TXN,SERPINE2,UGP2,PEX6,PSME2,ARL4C,TAP1,SELL,FANCI,IER3,BTG3,PLK4,AKR1B1,ANKRD12,CLDN4,IFIT1,PIM1,SCYL3,DOCK4,OPLAH,TNIP1,PRSS23,IFITM3,SLC39A8,STAT4,SAT1,LITAF,FBXO9,FNDC3A,PSMA4,KBTBD2,SPINT2,TMEM159,EHD1 |
| 7.253e-04 | -7.23 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | 194 | 34 | 17758 | 1761 |
GRN,LGALS3,S100A11,HEXB,ASAH1,KCTD12,SIRPA,ARHGEF10L,GNS,ATP6V0B,TNS3,TYMP,SLC16A6,PLCG2,BCL6,DAPK1,ACSL4,PTPRE,SNX10,SYK,CKAP4,GCA,TIMP2,PLSCR1,DIAPH2,NPC2,PCTP,FOS,ATP10D,CORO1C,NOD2,CTSA,ZMIZ1,SLC27A3 |
| 7.253e-04 | -7.23 | GSE3982_NKCELL_VS_TH1_DN | MSigDB lists | GSE3982_NKCELL_VS_TH1_DN | 194 | 34 | 17758 | 1761 |
ANXA3,GCLM,IL15RA,DEPDC1,NQO1,PTTG1,KIF5B,TNS3,NEK2,TUBG1,TSPAN13,KLF9,MANF,OAS3,SMYD5,MYO5A,CKS2,CENPA,C3orf52,GLO1,GTF2A2,KIF11,STEAP1,PRIM1,SLCO4A1,RBM47,TWSG1,AURKA,NCAPG2,CCNB2,UBE2C,ESPL1,E2F8,ACOT7 |
| 7.277e-04 | -7.23 | REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | REGULATION_OF_CATALYTIC_ACTIVITY | 271 | 44 | 17758 | 1761 |
CCNE2,SPRED1,CDKN1C,RALBP1,TP53,ERBB2,HERC5,PKN1,TRIB2,CARD10,CDKN2C,DIRAS3,CCND1,CARD8,PTEN,RGS3,MAP3K9,BAX,SERINC2,MDFIC,F2R,PLCB2,CDKN2D,CCDC88A,MDFI,CKS2,CASP9,STRADB,PKMYT1,PIF1,MAP3K6,CDK5R1,EDNRA,GNAS,CDK5RAP1,RBL1,MADD,FGD6,GLA,MAP3K5,AIFM3,IFI6,HIPK3,FGD1 |
| 7.291e-04 | -7.22 | FGF signaling pathway | Pathway Interaction DB | fgf_pathway | 47 | 16 | 2227 | 331 |
RUNX2,AKT1,SSH1,PLAUR,RPS6KA1,PIK3R1,FOS,FGF19,PLCG1,CDH1,FGFR2,PIK3CA,CTTN,NCAM1,GAB1,SPRY2 |
| 7.300e-04 | -7.22 | regulation of epithelial cell migration | biological process | GO:0010632 | 153 | 29 | 16441 | 1675 |
EPB41L5,ANXA3,AKT1,SOX9,RGCC,VASH1,HDAC6,PDGFB,ETS1,BCAR1,EMP2,SRPX2,NRP2,HDAC9,GPLD1,PLCG1,SVBP,ITGA3,SP100,ACVRL1,PLPP3,PRCP,CORO1C,DAB2IP,TACSTD2,EPB41L4B,ARSB,SEMA3A,HSPB1 |
| 7.339e-04 | -7.22 | Liver enzyme levels (alkaline phosphatase)(PMID:22001757) | GWAS genes | Liver enzyme levels (alkaline phosphatase)(PMID:22001757) | 8 | 5 | 2389 | 269 |
FADS2,FUT2,ABHD12,GPLD1,NBPF3 |
| 7.358e-04 | -7.21 | cellular response to nitrogen compound | biological process | GO:1901699 | 660 | 93 | 16441 | 1675 |
SPRED1,SORBS1,SLC2A4,SSH1,PSME2,NRG2,ERBB2,PSME1,ITPR2,BCL2L1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,CDH1,SHC3,KLF3,PIK3CA,AKR1B1,DAB2IP,GOT1,PDE4D,IFIT1,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,EZR,AGO4,PRKAR2B,PRKRA,POR,CASP4,RHEB,SOCS3,IRS2,ENPP1,IDE,JAK1,NOD2,CAB39,EIF4EBP2,SPTBN5,NRG1,GAB1,RRAGD,PRKAA2,CPEB4,RASA2,SOX9,CALM3,PSMD10,GABRG2,FGF19,HDAC9,IGF1R,COL6A1,ERBB3,NCAM1,MYO5A,PDGFC,RASGRF1,SHMT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,RASA1,GPLD1,GNAS,PRKAG2,FGFR2,SH3BP4,NR4A3,GRIN2D,NR4A2,GPER1,MAP3K5,TBC1D4,JAK3,CPEB2,COL16A1,TMEM173 |
| 7.360e-04 | -7.21 | stem cell development | biological process | GO:0048864 | 125 | 25 | 16441 | 1675 |
EPB41L5,SEMA6B,HES1,S100A4,RET,SOX9,TGFBR1,LOXL2,FAM101B,EFNB1,FGF19,EDNRA,PITX2,FGFR2,SEMA4D,CORO1C,BMP7,FAM83D,ADAM15,TWIST1,NRG1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 7.393e-04 | -7.21 | MODULE_474 | MSigDB lists | MODULE_474 | 17 | 7 | 17758 | 1761 |
LTBP1,NOV,IGFBP2,CTGF,IGFBP6,CYR61,SOCS3 |
| 7.393e-04 | -7.21 | MODULE_346 | MSigDB lists | MODULE_346 | 17 | 7 | 17758 | 1761 |
ASAH1,PLD1,GM2A,PLCG2,HEXB,GPX4,B4GALNT1 |
| 7.394e-04 | -7.21 | Thioredoxin_CS | interpro domains | IPR017937 | 17 | 7 | 18293 | 1814 |
PDIA3,DNAJC10,TXN,PDIA6,TMX4,PDIA5,PDIA4 |
| 7.410e-04 | -7.21 | PID_PI3KCI_PATHWAY | MSigDB lists | PID_PI3KCI_PATHWAY | 49 | 13 | 17758 | 1761 |
PLCG1,ARAP3,RHOA,PTEN,INPP5D,PLCG2,PIK3R1,PIK3CA,SGK1,PIK3CD,YES1,ARF6,SYK |
| 7.420e-04 | -7.21 | ZHANG_TLX_TARGETS_36HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_36HR_UP | 217 | 37 | 17758 | 1761 |
SORT1,TM2D2,SORBS1,PINK1,S100A11,TAP1,EMP2,SIRPA,PDGFA,OPN3,BAX,AOX1,SLC44A2,ADAM15,PLEKHF1,CITED2,PTPRE,CTDSP2,DVL2,IGDCC4,TIMP2,PQLC3,NR4A1,S100A4,SAT1,PIP4K2C,TNS1,TYSND1,MAPK8IP1,GABARAPL1,TAPBP,SCARB2,CSF1,CLIP4,OTUB2,TOB1,CPPED1 |
| 7.450e-04 | -7.20 | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | 87 | 19 | 17758 | 1761 |
CD55,CASP9,COL18A1,ARHGAP35,GNAS,PTPRF,PSMD1,GPRC5B,CDK16,GDE1,P4HA2,ITPR1,PGRMC1,SGK1,TMBIM6,PHKA2,MAP3K5,PLIN3,ATP2B1 |
| 7.450e-04 | -7.20 | SMITH_TERT_TARGETS_DN | MSigDB lists | SMITH_TERT_TARGETS_DN | 87 | 19 | 17758 | 1761 |
LAMP2,UGP2,AKT1,STAT4,ASAH1,ARHGDIB,OAT,TNFSF9,SIRPA,ABR,PGF,FOSB,ALDH7A1,AHCY,SERPINB6,L1CAM,ALDH3A2,GM2A,FAH |
| 7.487e-04 | -7.20 | in utero embryonic development | biological process | GO:0001701 | 350 | 55 | 16441 | 1675 |
GRN,EMX1,GRHL2,ADD1,CDKN1C,EPAS1,ST14,TP53,TGFBR1,BCL2L1,NCKAP1,CCNB1,STIL,PDGFB,ELF3,MECOM,RCN1,E2F7,CYR61,GATA2,FUT8,PLK4,NEK2,TWIST1,ZBTB18,WNT3A,MDFI,EPB41L5,HES1,AKT1,SALL4,UBE2A,TFAP2C,ICMT,ZFAND5,G2E3,SOCS3,EDNRA,HS6ST1,NCOA3,PLCG1,FGFR2,ACVRL1,SPINT2,PLOD3,FZD5,ZMIZ1,TANC2,SOX8,NCAPG2,CCNB2,E2F8,GAB1,MAFF,EGLN1 |
| 7.512e-04 | -7.19 | establishment of localization in cell | biological process | GO:0051649 | 1843 | 228 | 16441 | 1675 |
LAMP1,EXPH5,ACACB,CPT2,SLC25A13,ARFGEF1,NDC80,TAP1,TGOLN2,SYTL4,CCNB1,HDAC6,PDGFB,ERP29,SLC8B1,CALM2,ZFYVE16,RAB15,AP1M2,CTGF,DPYSL2,STEAP2,DLG1,SNX16,RAB20,RP2,TINAGL1,PIK3CD,CTTN,PACSIN1,TRAM1,MYRIP,S100A13,RASGRP1,LAMP2,CENPA,EZR,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,OPTN,TRIM9,WIPI1,GNPTAB,ATP7B,TRAF3IP1,RAB11FIP1,NOD2,F2RL1,PCSK5,PRKAA2,GRN,GGA1,PEX6,RAB23,CALM3,RAB6A,GPSM2,SLC1A3,FAM21C,MERTK,LMNA,ATG4A,DOPEY2,SNX18,GATA2,RIMS3,ATP5H,RPL39,KIF13B,RANBP1,EXOC8,SORL1,CADPS2,PIKFYVE,GAD1,SYTL3,NUP85,PPP6R1,RIMS2,KDELR1,TRAK2,PMPCB,CALM1,ERO1A,BTN3A2,STRADB,SCRIB,NPC2,STX3,GNAS,AP1AR,SCARB2,PRKAG2,TIMM8A,PVRL2,CDCA5,NFKBIA,ITPR1,FAM83D,ZDHHC7,CTSA,LTBP2,PLD1,NDE1,SHROOM2,HOOK1,JAK3,NRBP1,TOB1,NUP58,EHD1,MTM1,SLC25A24,CCDC109B,DLGAP5,UPF3B,TP53,FTH1,BCL2L1,EMP2,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,PDGFA,SVBP,ZDHHC12,KIF14,PLCG2,BCL6,ZDHHC23,RPN2,IFIT1,LMAN1,RAB27B,ARL4D,F2R,ATG4D,CHP1,PPIF,SEC23A,SEC61B,AKT1,COG2,FZD4,SYNE2,HTATIP2,KIF1C,NUSAP1,ATP1B1,RAB38,ITPR3,ATP10D,DAG1,TAPBP,ALDH5A1,DDOST,AXL,PEX2,SPTBN5,SYT13,PRIMA1,RGS14,SLC25A30,ABCA1,ANXA3,SORT1,CD63,ATP9A,HABP4,ARL4C,CDCA8,BTN3A1,PDIA3,CTSZ,AIP,VPS26A,HMGXB4,ZDHHC21,M6PR,PDIA4,KIF5B,ADORA1,MLPH,CTSC,LLGL2,CDK16,BAX,KLC3,CD9,ABCD1,SYK,SPRY2,MYO5A,SUN2,HES1,ZWINT,LCA5,RAB3B,ZC3H11A,PIK3R1,MRS2,FURIN,PRICKLE1,COL7A1,BBS2,SCRN2,RPL12,SERPINA1,FGFR2,RAB11FIP2,SYT7,SCG2,NR4A3,ARRB1,SPCS3,MCUR1,CENPE,GEM,ARSB,NDFIP1,ESPL1,ABCG1,SNPH |
| 7.543e-04 | -7.19 | BROWNE_HCMV_INFECTION_18HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_UP | 172 | 31 | 17758 | 1761 |
PRKAA2,ENPP4,ZWINT,PPP1R2,IL15,ATP8A1,SLC25A13,ETV5,TAP1,MRAS,KCTD2,DCP2,CD83,PDIA4,CDS1,M6PR,MAN2A2,HSF2,SLC25A4,GPRC5B,NFKBIA,TRAF3IP1,MITF,RUNDC3B,KCNS3,WWP1,ERBB3,MPHOSPH9,RASGRP1,OCLN,PKIA |
| 7.588e-04 | -7.18 | DER_IFN_ALPHA_RESPONSE_UP | MSigDB lists | DER_IFN_ALPHA_RESPONSE_UP | 74 | 17 | 17758 | 1761 |
MX1,PLSCR1,HLA-E,TAP1,PSME1,IFIT3,HLA-A,FAS,ATP6V0B,PLOD2,NMI,IRF2,TRIM21,IFIT1,HLA-C,COL16A1,IFI6 |
| 7.613e-04 | -7.18 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | 187 | 33 | 17758 | 1761 |
CKAP2,DNAJC3,ITGA6,BLVRB,NENF,ISOC2,B4GALT4,NUCB2,SDC1,ARHGEF16,LMNA,PDIA4,RCN1,TYMP,BHLHE41,CST3,RRBP1,CITED2,CKAP4,KDELR1,FAH,LAMP2,PODXL2,TIMP2,RAPGEF2,COL7A1,OPTN,MDK,UAP1,SLC25A4,WIPI1,IFI6,MAPK12 |
| 7.613e-04 | -7.18 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | 187 | 33 | 17758 | 1761 |
CCNI,IL15,RUSC2,ABCG2,ARFGEF1,CD274,LACTB2,TMCC3,ATP6V0B,TAF1B,IGSF9,SNX18,HLA-C,RASGRP1,HMMR,SYPL1,HPS3,ADCK3,IFITM3,AMFR,PRICKLE1,FNDC3A,C3orf58,ABR,FZD7,SOCS3,JAK1,GNPTAB,SFMBT1,AGFG2,CMPK2,IFIH1,RNF146 |
| 7.613e-04 | -7.18 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | 187 | 33 | 17758 | 1761 |
ARL4C,SEPP1,FAM101B,SLC20A1,DENND2D,APPBP2,ADD3,LRRC6,METTL7A,LMO4,CYP2S1,SGK1,MYLIP,ALS2CL,RASGRP1,PAQR7,SMARCA2,ING1,PLEKHO1,SYNE2,ATP1B1,GALNT7,PDIK1L,STK17B,KCNMB4,MSL1,PPP2R5A,ACVRL1,SCG2,NR4A3,CTSA,ATP1B3,KLF7 |
| 7.638e-04 | -7.18 | MHCCLASSI | prints domains | PR01638 | 9 | 5 | 4759 | 462 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 7.663e-04 | -7.17 | V$NFAT_Q4_01 | MSigDB lists | V$NFAT_Q4_01 | 256 | 42 | 17758 | 1761 |
PPP4R4,PACSIN2,HSPG2,SOX9,MIER3,NDRG2,NKRF,HMGN3,NOTUM,ISYNA1,DHRS3,HOXB2,PRRG4,PPP2R3A,IER3,TFAP4,FOXP2,RNF220,ADRBK1,RNF128,SLC16A6,RGS3,MITF,AKR1B1,RASGEF1A,TIAM1,RHOA,ELK3,FOS,PITX2,TMEM54,PLOD2,NR4A3,KLF5,NR4A2,MDH1,ATP1B3,SEMA3A,NR3C2,PTGES,DEF6,JARID2 |
| 7.682e-04 | -7.17 | human chr12q22 | chromosome location | human chr12q22 | 29 | 8 | 26250 | 1887 |
FGD6,NTN4,VEZT,NDUFA12,LTA4H,NR2C1,METAP2,TMCC3 |
| 7.721e-04 | -7.17 | labyrinthine layer development | biological process | GO:0060711 | 48 | 13 | 16441 | 1675 |
HES1,HS6ST1,NCOA3,GRHL2,AKT1,CYR61,ST14,FGFR2,SPINT2,FZD5,GAB1,SOCS3,EGLN1 |
| 7.721e-04 | -7.17 | exocrine system development | biological process | GO:0035272 | 48 | 13 | 16441 | 1675 |
NKX3-1,IGF1R,TWSG1,FGFR2,BMP7,CST3,SOX9,PLXNA1,SEMA3A,NFIB,DAG1,RARG,IGSF3 |
| 7.762e-04 | -7.16 | INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | INTRACELLULAR_PROTEIN_TRANSPORT | 143 | 27 | 17758 | 1761 |
NFKBIE,AKT1,PEX6,COG2,GGA1,PDIA3,STRADB,ICMT,BARD1,ERP29,ZFYVE9,APPBP2,OPTN,ATG4A,KLHL2,ZFYVE16,AP1M2,CDH1,KIF13B,BCL6,CTSA,LTBP2,F2R,TRAM1,KDELR1,ATG4D,MDFI |
| 7.780e-04 | -7.16 | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | MSigDB lists | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | 94 | 20 | 17758 | 1761 |
CCNI,SLC2A4,HSPG2,S100A11,S100A4,RASA2,CALB2,SCRIB,RNF113A,FAS,SNTA1,ITGB8,LIMK1,NR4A3,BCL6,RYK,VAT1,MTMR11,TOB1,CKAP4 |
| 7.780e-04 | -7.16 | NIELSEN_GIST | MSigDB lists | NIELSEN_GIST | 94 | 20 | 17758 | 1761 |
CTDSPL,CCDC68,PRKAR2B,PRKCQ,FOS,ANO1,DNAJB9,WWP2,STK17A,APLP2,CA2,SLC4A4,MGAT4A,IMPAD1,ABCB1,ARRB1,SLC12A2,BTBD3,CMTM4,CRTAP |
| 7.780e-04 | -7.16 | MODULE_169 | MSigDB lists | MODULE_169 | 94 | 20 | 17758 | 1761 |
TXN,IL15RA,CR2,PRKAR2B,HEATR5A,TRIB2,ASB13,FOS,TSPAN7,STK17A,IER3,TNS3,BMP7,BCL6,DAPK1,SORL1,SLC39A10,MYBL1,AHR,ABCC1 |
| 7.815e-04 | -7.15 | negative regulation of cytoplasmic transport | biological process | GO:1903650 | 105 | 22 | 16441 | 1675 |
TXN,ERLEC1,NFKBIE,THRA,LITAF,RAB23,PSMD10,BARD1,APC2,SNX12,NOV,SP100,BMP7,CABP1,NFKBIA,UBE2J1,DAB2IP,MDFIC,YOD1,PKIA,MDFI,CHP1 |
| 7.846e-04 | -7.15 | TGTTTGY_V$HNF3_Q6 | MSigDB lists | TGTTTGY_V$HNF3_Q6 | 696 | 95 | 17758 | 1761 |
LTBP1,CEP70,REPS2,THRA,TSC22D3,FHDC1,IL18,OSR2,OAT,DENND2D,EPS8L2,RAD23A,SIPA1L2,SESN3,ST5,CTGF,GRHL1,SHC3,NPNT,WDR44,RGS3,ELF5,KLF3,FOSB,MITF,SLC44A1,BCL6,DUSP10,CRY2,NTN4,PDE4D,ZNF462,SMARCA2,KCNIP3,SYNE2,CBX6,KIF13A,ITPR3,H2AFV,SP4,TAPBP,RBM47,KLF12,NKD1,NRG1,KLF5,EFNA5,REEP4,HOXC13,BMF,FRMD4A,ZNF395,NFKBIE,FAM134A,TGFBR1,CNTNAP2,CRABP2,TSPAN7,PPP2R3A,TFAP4,FOXP2,ITGA3,CYR61,CALD1,BDH1,SGK3,SGK1,ADAM15,TAGLN2,ERBB3,CITED2,NCAM1,MAST4,NFE2L3,TGIF1,PHF20L1,LONRF3,MGAT4B,PDIK1L,MUM1L1,PRX,GPLD1,PITX2,SERPINA1,H1F0,NR4A3,EGFL7,SEMA3A,SHROOM2,TOB1,RNF146,KLF7,JARID2,GOLGB1,DOCK9 |
| 7.850e-04 | -7.15 | NEK4 (NIMA-related kinase 4) | protein interactions | 6787 | 16 | 7 | 16036 | 1726 |
HLA-B,NRG1,HLA-C,HLA-E,PLAUR,DNAJB2,CTDSP2 |
| 7.850e-04 | -7.15 | Bub1 (budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)) | protein interactions | 12235 | 16 | 7 | 16036 | 1726 |
BUB1,NUF2,ZWINT,PDE4D,SPC25,CDC20,NDC80 |
| 7.850e-04 | -7.15 | GLB1 (galactosidase beta 1) | protein interactions | 2720 | 16 | 7 | 16036 | 1726 |
PLK1,CTNNBIP1,CTSA,FBXO6,LGALS3,FOS,DNAJB2 |
| 7.900e-04 | -7.14 | PLASMA_MEMBRANE | MSigDB lists | PLASMA_MEMBRANE | 1389 | 173 | 17758 | 1761 |
LAMP1,BCAM,SSH1,SLC25A13,EPHA4,F11R,SYTL4,ITPR2,CACNB4,DNER,SLC20A1,SDC1,GRM5,HTR1D,CALM2,EPCAM,CTGF,STIM1,IL6ST,DLG1,STEAP2,FUT1,TRPC1,CLDN4,TACSTD2,SGCE,CD55,ACVR1C,SNTB2,ROR1,SLC25A5,EDNRA,HS6ST1,KCNMB4,SLC25A4,KCNK1,ATP7B,MADD,NOD2,ARF6,F2RL1,CD99,PRSS8,LGALS3,FXYD3,CALM3,MERTK,IL18R1,TSPAN7,ITGA3,LYPD3,KCNN4,SLC16A6,OPN3,SORL1,CD70,CACNA1D,PIKFYVE,NCAM1,SLC12A2,NUP85,CCDC88A,ABCC1,TRAK2,FADS2,PODXL2,PCDH1,MMD,MFI2,RGMB,CALM1,EPHA1,STEAP1,GNA11,STX3,GNAS,PTPRF,MMP15,GABRD,SCARB2,SLC4A4,PVRL2,COL13A1,ITPR1,SLC4A3,ATP1B3,SHROOM2,SLC2A4,SORBS1,NF2,IL15,ST14,CD82,HDAC11,PKP2,MRAS,IL27RA,IL13RA1,SLC7A2,DDR1,APC2,BCAP31,SYTL2,CDH1,NOTCH3,EPHB4,F2R,GCA,AKT1,PTPRU,UTRN,SLC11A2,ERBB2IP,ATP1B1,ITPR3,CD40,DAG1,FZD7,PTPRJ,ATP1A1,SHROOM3,AXL,MMP17,PTK7,EFNA5,HS3ST3B1,AIFM3,LIFR,ABCA1,TSPAN15,CD63,SELL,GABRG2,CYB561,TGFBR1,NUCB2,EFNB1,FZD6,SIRPA,M6PR,NEO1,IL17RB,ADORA1,ITGB8,ATP8B1,TMBIM6,TSPAN13,ERBB3,SGCB,SYK,SLC16A5,ATP2B1,SYPL1,ERMAP,PLSCR1,IFITM3,MPP1,PLAUR,GRIN1,AIF1L,SNTB1,BCAR1,RNPEP,CD83,CNTNAP1,ACVRL1,PGRMC1,RYK,ARRB1,FZD5,OCLN,ABCG1,CD33 |
| 7.903e-04 | -7.14 | Insulin Signaling | WikiPathways | WP481 | 163 | 33 | 4455 | 516 |
PRKAA2,SLC2A4,SORBS1,RPS6KA1,KIF5B,RPS6KA2,IGF1R,PTEN,SHC3,SGK3,PIK3CA,MAP3K9,SGK1,MAPK11,PIK3CD,MAP3K3,AKT1,PIK3R1,PRKCQ,ELK1,FOS,MAP3K6,RHEB,SOCS3,PTPRF,IRS2,ENPP1,MAP3K5,ARF6,TBC1D4,GAB1,EHD1,MAPK12 |
| 7.965e-04 | -7.14 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | 195 | 34 | 17758 | 1761 |
LASP1,DLGAP5,EPAS1,IQGAP1,NDC80,CCNB1,BARD1,IL18R1,HLA-A,EPS8L2,APOBEC3B,FUT8,MAPK11,FAM69A,ARAP2,PSMB4,TACC1,ASPM,STAT4,NUSAP1,KIF11,RASGRP2,OPTN,SLCO4A1,P4HA2,CSTF2,HDAC1,STK39,CENPE,PIEZO1,CCNB2,ESPL1,MELK,EHD1 |
| 7.965e-04 | -7.14 | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_UP | 195 | 34 | 17758 | 1761 |
TM2D2,TTC39B,NFKBIE,CHCHD7,HEBP1,TSC22D3,LRP4,HEXB,ARFGEF1,NUF2,BARD1,PQLC2,CNTRL,KLF3,TPST1,SLC44A2,SNX16,CTDSP2,RBMS2,HES1,GCA,UTRN,HMG20B,TNS1,RNPEP,SP4,ATP13A2,HLA-B,ABCB1,STK39,GLA,RGS14,HSPB1,ABCG1 |
| 7.975e-04 | -7.13 | GSE3982_MAST_CELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BASOPHIL_DN | 180 | 32 | 17758 | 1761 |
ZNF395,EPAS1,DNAJC3,ARL4C,OSGIN2,PJA2,CA8,HLA-A,ZFYVE16,ADD3,TRANK1,UBE2J1,PDE4D,ULBP2,CTDSP2,PCDH1,FBLN5,ARAP2,ADCK3,FOXJ2,UTRN,ARHGDIB,ATP10D,BCAR3,TMEM164,ETS2,JAK1,PPP2R5A,KBTBD2,CCDC69,USF2,PTGES |
| 8.016e-04 | -7.13 | TBCE (tubulin folding cofactor E) | protein interactions | 6905 | 12 | 6 | 16036 | 1726 |
AHCY,ARF6,GNPDA1,NFKBIA,TBCD,RAD23A |
| 8.016e-04 | -7.13 | PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) | protein interactions | 9088 | 12 | 6 | 16036 | 1726 |
PLK1,PLIN3,CCNB1,PTEN,CDK1,SPINT2 |
| 8.044e-04 | -7.13 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 900 | 118 | 17775 | 1757 |
LTBP1,SLC25A24,TRIP10,TMEM41B,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,DDR1,RCN1,DAPK2,WEE1,RPS6KA2,SP100,PIK3CA,PLK4,EPHB4,NEB,SCYL3,PLK1,MAP3K3,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,PRKAR2B,ROR1,PKMYT1,IDH1,MAP3K6,ADRBK2,STK17B,ABR,EPHA10,PLCG1,MFAP3L,DUOX1,PTPRJ,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,BMP1,MLKL,MAPK12,PRKAA2,PINK1,CDK17,TGFBR1,ADCK5,ISYNA1,PKN1,TRIB2,DSE,MERTK,BMP2K,SNTA1,TMEM87B,IGF1R,ADRBK1,CDK16,PTEN,LLGL2,KIF13B,NEK2,DAPK1,SGK3,MAP3K9,ADCK2,PRKG1,CD9,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MYLIP,SYK,MYO5A,ABCC1,ADCK3,TESK1,ASPM,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,RANBP9,BSDC1,STK17A,GNAS,MAPKAPK2,FAT4,ACVRL1,FGFR2,PRCP,ALPK3,AURKA,CABIN1,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,MELK,GOLGB1 |
| 8.048e-04 | -7.12 | Prolonged ERK activation events | REACTOME pathways | R-HSA-169893 | 235 | 41 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PLCG1,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.051e-04 | -7.12 | RAB27A (RAB27A, member RAS oncogene family) | protein interactions | 5873 | 30 | 10 | 16036 | 1726 |
EXPH5,MLPH,FBXO6,SYTL4,LRIF1,MYRIP,SYTL3,MYO5A,SYTL2,RIMS2 |
| 8.059e-04 | -7.12 | Degradation of the extracellular matrix | REACTOME pathways | R-HSA-1474228 | 89 | 20 | 8202 | 867 |
CASP3,COL9A3,TIMP2,HSPG2,FURIN,COL18A1,COL12A1,MMP15,CTSL,CDH1,COL13A1,MMP17,CTSV,BMP1,ADAM15,KLK7,COL16A1,CAPN1,TLL2,ADAMTS16 |
| 8.067e-04 | -7.12 | GENTILE_UV_HIGH_DOSE_DN | MSigDB lists | GENTILE_UV_HIGH_DOSE_DN | 304 | 48 | 17758 | 1761 |
CASP3,SSH1,TRIP10,TSC22D3,ITGA6,GNE,EPS8,ARL4C,C5orf30,KIF23,CCNB1,TRIB2,TIPRL,HOXB2,LBR,HMGXB4,SS18,WEE1,CTGF,CYR61,GATA2,ZFP36,PLK4,TPST1,PIKFYVE,TIPARP,CTDSP2,CKS2,CENPA,NR3C1,RAPGEF2,SAT1,ZFAND5,LHFPL2,STX3,FZD7,STK17A,BCAR3,NCOA3,UAP1,COL13A1,RND3,TLE1,AURKA,GEM,ZMIZ1,ARF6,MAFF |
| 8.079e-04 | -7.12 | CELL_CYCLE_GO_0007049 | MSigDB lists | CELL_CYCLE_GO_0007049 | 312 | 49 | 17758 | 1761 |
CCNE2,DLGAP5,CDKN1C,CIT,NDC80,TP53,KIF23,HERC5,SAC3D1,CCND1,CDKN2C,DIRAS3,BTG3,PTEN,BMP7,DLG1,NEK2,CDKN1B,TUBG1,BUB1,CITED2,CDKN2D,MPHOSPH9,CKS2,REC8,PLK1,SUN2,ZWINT,CDC20,NUSAP1,RUNX3,RAD17,PKMYT1,ANLN,SESN1,KIF11,CDK5R1,CDK5RAP1,DHRS2,CDCA5,MADD,SH3BP4,AURKA,CENPE,NDE1,UBE2C,ESPL1,AHR,MAPK12 |
| 8.086e-04 | -7.12 | focal adhesion | cellular component | GO:0005925 | 390 | 59 | 17570 | 1756 |
CD99,LMO7,LASP1,FBLIM1,SORBS1,PACSIN2,MRC2,ADD1,HSPG2,ITGA6,IQGAP1,SDC4,PDIA3,KIF23,NCKAP1,SDC1,SH3KBP1,TNS3,ITGA3,CDH1,FLRT3,CD9,IRF2,DIXDC1,CTTN,TLN2,CHP1,EPB41L5,RHOA,SNTB2,PLAUR,SYNE2,EZR,TNS1,YES1,SNTB1,AIF1L,ALCAM,BCAR1,DAG1,ARHGAP24,SCARB2,RPL12,JAK1,RND3,PVRL2,LIMK1,PTK7,CORO1C,TRIOBP,ITGAV,FHL1,HMGA1,ARPC2,ARF6,HSPB1,AFAP1,L1CAM,CAPN1 |
| 8.103e-04 | -7.12 | MEMBRANE | MSigDB lists | MEMBRANE | 1922 | 231 | 17758 | 1761 |
LAMP1,SIGIRR,BCAM,SSH1,SLC25A13,EPHA4,F11R,SYTL4,ITPR2,CACNB4,DNER,SLC20A1,SDC1,SLC9A7,GRM5,ABCD4,HTR1D,CALM2,EPCAM,CTGF,STIM1,IL6ST,SLC44A1,DLG1,STEAP2,FUT1,ABCA2,TRPC1,CLDN4,TACSTD2,TRAM1,LAMP3,LAMP2,SGCE,CD55,MCTP1,ACVR1C,SNTB2,EZR,ROR1,SLC25A5,EDNRA,ENPP1,HS6ST1,KCNMB4,SLC25A4,KCNK1,GDE1,DOLPP1,ATP7B,MADD,NOD2,ARF6,F2RL1,CD99,PRSS8,LGALS3,FXYD3,ABCG2,CALM3,B4GALT4,MERTK,IL18R1,TSPAN7,DOPEY2,ITGA3,LYPD3,KCNN4,SLC16A6,OPN3,FXYD5,SORL1,CD70,CACNA1D,PIKFYVE,NCAM1,SLC12A2,NUP85,CCDC88A,CKAP4,KDELR1,ABCC1,TRAK2,FADS2,PODXL2,PCDH1,MMD,MFI2,RGMB,CALM1,EPHA1,STEAP1,GNA11,STX3,CDK5R1,GNAS,PTPRF,MMP15,GABRD,SCARB2,SLC4A4,PVRL2,COL13A1,ITPR1,SLC4A3,ATP1B3,PLD1,SHROOM2,NRBP1,SLC2A4,SORBS1,NF2,IL15,ST14,CD82,RALBP1,HDAC11,PKP2,IL13RA1,MRAS,IL27RA,SLC7A2,AIFM2,APC2,EMP2,DDR1,BCAP31,SYTL2,ATP6V0B,MUC16,CDH1,VAT1,RPN2,NOTCH3,EPHB4,ECE1,LMAN1,TSPAN1,F2R,GCA,CLCN3,AKT1,FZD4,COG2,PTPRU,CYB5R2,PTGER4,UTRN,HTATIP2,IGSF8,SLC11A2,ERBB2IP,ATP1B1,ITPR3,CD40,DAG1,FZD7,TAPBP,ATP1A1,PTPRJ,DDOST,SHROOM3,PTK7,SLC9A6,WFS1,AXL,MMP17,PEX2,SECTM1,EFNA5,HS3ST3B1,AIFM3,LIFR,ABCA1,GOLIM4,CD63,TSPAN15,GABRG2,SELL,CYB561,TGFBR1,NUCB2,SBF1,LBR,EFNB1,SLC9A2,SIRPA,FZD6,NEO1,M6PR,IL17RB,ADORA1,ITGB8,BAX,SLC44A2,ATP8B1,TMBIM6,TSPAN13,ERBB3,SGCB,SYK,SLC16A5,ATP2B1,GCNT1,SYPL1,ERMAP,PLSCR1,IFITM3,MPP1,AMFR,PLAUR,GRIN1,PRICKLE1,SNTB1,AIF1L,BCAR1,RNPEP,CD83,GALNT3,CNTNAP1,ACVRL1,SPINT2,PGRMC1,RYK,ABCB1,ARRB1,FZD5,OCLN,GOLGB1,ABCG1,CD33 |
| 8.118e-04 | -7.12 | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | MSigDB lists | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | 27 | 9 | 17758 | 1761 |
PLA2G4A,ETV5,TFAP2A,SOX8,RAB27B,DUSP4,IQGAP3,GAD1,IFI6 |
| 8.118e-04 | -7.12 | WOTTON_RUNX_TARGETS_DN | MSigDB lists | WOTTON_RUNX_TARGETS_DN | 27 | 9 | 17758 | 1761 |
SIPA1L2,ADD3,ENO2,PLOD2,NR3C1,EGLN3,FNDC3A,ALCAM,XDH |
| 8.119e-04 | -7.12 | protein homodimerization activity | molecular function | GO:0042803 | 707 | 98 | 16491 | 1673 |
ADD1,S100A11,CRYM,THRA,HEXB,TAP1,BCL2L1,PDGFB,ERP29,SLC8B1,BARD1,SLC9A7,PDGFA,HSF2,SP100,IL6ST,CABP1,ALDH1A3,SRR,DAB2IP,TWIST1,ECE1,PTPRE,S100A13,APOBEC3G,NR2C1,NAGA,SMAGP,RASGRP1,SEPHS1,GCA,CLCN3,TRIM8,RIPK2,FZD4,CDA,CR2,GTF2A2,PRKRA,IDH1,TP53I3,TRIM9,ENPP1,IDE,ALDH5A1,DNM1L,STK26,BHLHB9,SLC27A1,ANXA9,GLA,RAP1GAP,E2F8,LRP4,ABCG2,ANO1,MECOM,TFAP4,FOXP2,TOP2A,CARD8,FLRT3,BHLHE41,BAX,MAP3K9,TFAP2A,ABCD1,ERBB3,S100A6,CCDC88A,PVRL4,HES1,PDGFC,SHMT1,FBLN5,ANO6,NADK2,EIF2AK1,PRDX4,PITX2,NUDT16,PVRL2,RAB11FIP2,FGFR2,DCK,CSF1,PRPS2,TBX18,NR4A3,S100A5,NR4A2,MAP3K5,USF2,NRBP1,ACOT7,TMEM173,ABCG1,XDH |
| 8.138e-04 | -7.11 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 68 | 16 | 17758 | 1761 |
PLA2G4A,CENPA,FURIN,COL18A1,OAT,PDGFA,TIMP3,CTGF,RBL1,GATA2,CSF1,DCK,PLK4,NCAM1,S100A6,CYP1B1 |
| 8.152e-04 | -7.11 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 122 | 24 | 17758 | 1761 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,FGFR2,CNTRL,PIK3CA,CDKN1B,SPRY2,GAB1,FRS3 |
| 8.157e-04 | -7.11 | GAB1 signalosome | REACTOME pathways | R-HSA-180292 | 102 | 22 | 8202 | 867 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,IRS2,PDGFA,PTEN,FGFR2,PHLPP2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 8.183e-04 | -7.11 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | 81 | 18 | 17758 | 1761 |
SUN1,GCLM,BCAM,CENPA,HJURP,KIF20A,MPP1,CDCA8,ASB9,BCL2L1,MAN2A2,CTGF,ETS2,ELMO2,IMPAD1,FHL1,PLIN3,XKR8 |
| 8.196e-04 | -7.11 | execution phase of apoptosis | biological process | GO:0097194 | 79 | 18 | 16441 | 1675 |
CASP3,ADD1,AKT1,ACVR1C,PRKCQ,BCAP31,CASP4,LMNA,TOP2A,CDH1,STK26,DNM1L,H1F0,MADD,GPER1,AIFM3,OCLN,XKR8 |
| 8.233e-04 | -7.10 | KANG_FLUOROURACIL_RESISTANCE_UP | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_UP | 22 | 8 | 17758 | 1761 |
MDK,DDB2,LZTFL1,NOV,BTG3,NQO1,OSBPL3,IGFBP2 |
| 8.287e-04 | -7.10 | KIM_WT1_TARGETS_12HR_DN | MSigDB lists | KIM_WT1_TARGETS_12HR_DN | 203 | 35 | 17758 | 1761 |
CCNE2,NF2,SSH1,IL18,KBTBD11,ARHGEF40,ETS1,PHLDA1,CCND1,CTGF,CYR61,CALD1,ELF5,GTF2F2,LIMCH1,MANF,RIMS2,SMAGP,IGSF3,ELK3,PLSCR1,EZR,ARFRP1,SPTLC2,ZFAND5,STEAP1,CASP4,CDK5R1,PLOD2,RND3,CORO1C,PLK2,RAP2C,TMC5,NRG1 |
| 8.287e-04 | -7.10 | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 203 | 35 | 17758 | 1761 |
PINK1,CIT,RPS6KA1,TESK2,TGFBR1,DAPK2,RPS6KA2,SGK3,MAP3K9,PLK4,NEK2,SGK1,MAPK11,PIM1,PHKA2,MAP3K3,PLK1,RIPK2,AKT1,TESK1,ACVR1C,PBK,EIF2AK1,XRCC6BP1,MAP3K6,STK17B,CDK1,STK17A,MAPKAPK2,ACVRL1,STK38,LIMK1,MAP3K5,HIPK3,MAPK12 |
| 8.298e-04 | -7.09 | SHC1 events in ERBB2 signaling | REACTOME pathways | R-HSA-1250196 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.298e-04 | -7.09 | GRB2 events in EGFR signaling | REACTOME pathways | R-HSA-179812 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.298e-04 | -7.09 | SHC1 events in EGFR signaling | REACTOME pathways | R-HSA-180336 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.298e-04 | -7.09 | SOS-mediated signalling | REACTOME pathways | R-HSA-112412 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.298e-04 | -7.09 | RAF/MAP kinase cascade | REACTOME pathways | R-HSA-5673001 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,NRG2,CALM3,PSME1,PDGFB,FGF19,SPTB,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,JAK1,PPP2R5A,FGFR2,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3 |
| 8.298e-04 | -7.09 | GRB2 events in ERBB2 signaling | REACTOME pathways | R-HSA-1963640 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.298e-04 | -7.09 | SHC1 events in ERBB4 signaling | REACTOME pathways | R-HSA-1250347 | 228 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 8.317e-04 | -7.09 | negative regulation of defense response | biological process | GO:0031348 | 140 | 27 | 16441 | 1675 |
PSMB4,NLRX1,ITCH,MICB,HLA-E,PBK,PTGER4,PPARA,TAP1,ETS1,GSTP1,ABR,HLA-A,SOCS3,IER3,HLA-B,NOV,ADORA1,TSPAN6,TRAF3IP1,NMI,NOD2,NLRC5,DUSP10,GPER1,IFIT1,NDFIP1 |
| 8.330e-04 | -7.09 | sclerosing | COSMIC cancer mutations | sclerosing | 62 | 15 | 17775 | 1757 |
GNAS,CDKN2C,ARAP3,AKT1,FGFR2,ITGA7,PIK3R1,RET,PIK3CA,TP53,TMEM143,ERBB2,IDH1,GNA11,FRMD4B |
| 8.336e-04 | -7.09 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | 173 | 31 | 17758 | 1761 |
TXN,MFI2,LONRF3,GNPDA1,TMEM55B,PLEKHO1,LHFPL2,STX3,RHEB,BCAR3,ANKRD10,SCARB2,SLCO4A1,ANKS6,PRKAG2,CORO1C,CSF1,ITPR1,ADCK2,SGK1,BRI3,NR4A2,TNFRSF12A,GLA,GEM,PTPRE,SPRY2,NRBP1,WBP5,RRAGD,CKS2 |
| 8.374e-04 | -7.09 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_DN | 188 | 33 | 17758 | 1761 |
GRN,PARP12,ARMCX3,IL15RA,TBC1D1,PSME2,RASA2,CUL4B,PDCL,TMCC3,ZFP36,FOSB,SMAGP,ENPP4,FIGNL1,FOXJ2,PIK3R1,NUB1,RC3H2,SERTAD3,RNPEP,RANBP9,ARHGAP24,MSL1,RBL1,RND3,P4HA2,NFKBIZ,ETAA1,RGS14,NRBP1,TMEM131,ABCG1 |
| 8.374e-04 | -7.09 | GSE2826_WT_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_DN | 188 | 33 | 17758 | 1761 |
CASP3,GOLIM4,PINK1,UGP2,EPAS1,FHDC1,ABCG2,IL18,DNAJB9,DAPK2,PAQR7,B3GALT6,CPD,S100A4,ATP1B1,RNPEP,NFIX,DPYSL3,FECH,GALNT3,AHRR,ENPP1,P4HA2,CORO1C,AXL,PTER,MATN2,S100A5,AURKA,ARRB1,SERPINB6,ATP1B3,RAB3IL1 |
| 8.416e-04 | -7.08 | lung-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-squamous_cell_carcinoma | 15429 | 1567 | 17775 | 1757 |
HECA,AK7,SLC25A13,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,TMEM159,TMEM173,ADAMTS16,DOCK9,TPRN,NQO1,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,TMEM200B,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,ZNF618,SNX12,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,FAM20B,BAX,ZFAND4,FAM102A,IGFBP2,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,CNTNAP1,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PARP12,RUNX2,HJURP,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,LBR,AIP,VPS26A,PARM1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,TFAP2A,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,CAMK1D,VASH1,OAT,PJA2,SLC9A7,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TNFRSF19,S100A2,TSPAN7,PSIP1,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,PBX3,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ASB9,ABCG2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,APOL2,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,OSR2,KCTD9,ZNF687,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,ADD1,MRPS15,AASS,MMADHC,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,NDE1,DRP2,ZNF502,SERPINB1,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,ENPP4,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,TTC8,TNRC6C,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,PDIA4,NEO1,DTX3L,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,CHCHD7,UBASH3B,ZCCHC24,CNTNAP2,B4GALT4,C3orf18,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,EPN3,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,EFR3A,PLCG2,LHX6,MINPP1,EGLN3,SCN2A,DVL2,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,DUOX1,DNAJC10,ATP1A1,PRRT4,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,PRDX4,FUCA1,BANK1,CDKN2AIPNL,FAT4,SERPINA1,ZNF214,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,MTMR11,RCAN3,PACSIN1,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,MCFD2,CCNF,SAV1,SLC25A5,ZFAND5,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,KIF23,C6orf106,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,PIKFYVE,RIMS2,IGSF3,EPB41L5,PMPCB,DDB2,FADS2,B3GNT7,MFI2,ZNF84,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,PRKCQ,SLC11A2,C15orf39,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,SIX4,LGALS3BP,TMCC3,AKIRIN1,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,CPT2,CAMKK1,FLYWCH2,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,VSIG10,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,ARMC7,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 8.471e-04 | -7.07 | negative regulation of transport | biological process | GO:0051051 | 448 | 67 | 16441 | 1675 |
TXN,LGR4,THRA,SYTL4,BARD1,APC2,ERP29,IER3,CALM2,NOV,SP100,CABP1,DAB2IP,TWIST1,ACSL4,PACSIN1,F2R,CHP1,PPIF,ERLEC1,AKT1,ACVR1C,PTGER4,EZR,SLC25A5,SNX12,ABR,IRS2,TRIM9,ENPP1,RAB11FIP1,CAB39,NRG1,ARF6,F2RL1,PACSIN2,NFKBIE,LGALS3,SERPINE2,RAB23,PSMD10,CALM3,ANO9,FBLN1,NEO1,WWP2,GNB5,ADORA1,PTEN,BMP7,UBE2J1,TMBIM6,MDFIC,ERBB3,MDFI,CALM1,RGCC,LITAF,BANK1,NFKBIA,YOD1,STK39,ITGAV,TBC1D4,NDFIP1,PKIA,PROM2 |
| 8.477e-04 | -7.07 | BIOCARTA_IL2RB_PATHWAY | MSigDB lists | BIOCARTA_IL2RB_PATHWAY | 38 | 11 | 17758 | 1761 |
JAK1,AKT1,NMI,PIK3R1,PIK3CA,BCL2L1,FOS,JAK3,SYK,FAS,SOCS3 |
| 8.477e-04 | -7.07 | PROTEIN_KINASE_REGULATOR_ACTIVITY | MSigDB lists | PROTEIN_KINASE_REGULATOR_ACTIVITY | 38 | 11 | 17758 | 1761 |
CDKN2C,CDKN1C,DNAJC3,MADD,CDKN1B,PRKAR2B,CDKN2D,MAPK8IP1,CDK5R1,PKIA,SOCS3 |
| 8.517e-04 | -7.07 | P4Hc | smart domains | SM00702 | 16 | 7 | 9131 | 997 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 8.533e-04 | -7.07 | MHC_I_a | interpro domains | IPR027648 | 9 | 5 | 18293 | 1814 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 8.621e-04 | -7.06 | PROTEIN_KINASE_CASCADE | MSigDB lists | PROTEIN_KINASE_CASCADE | 289 | 46 | 17758 | 1761 |
SPRED1,PINK1,NF2,PKN1,SLC20A1,CARD10,DAPK2,CARD8,RPS6KA2,PTEN,TSPAN6,RGS3,IL31RA,MAP3K9,DAPK1,SLC44A2,DUSP10,MDFIC,MAPK11,F2R,MDFI,MAP3K3,RHOA,RIPK2,STAT4,LITAF,DUSP4,CD40,MAP3K6,STK17B,MAPK8IP1,SOCS3,STK17A,PRDX4,MAPKAPK2,SCG2,PLK2,STK38,MADD,SECTM1,NMI,NR4A3,NOD2,MAP3K5,TRAF5,NDFIP1 |
| 8.667e-04 | -7.05 | EGFR1 Signaling Pathway | WikiPathways | WP437 | 177 | 35 | 4455 | 516 |
REPS2,RPS6KA1,RALBP1,EPS8,REPS1,SH3KBP1,ELF3,RPS6KA2,PLCG2,PIK3CA,PIK3CD,SPRY2,MAP3K3,TGIF1,TNIP1,AKT1,PLSCR1,ITCH,SH3BGRL,PIK3R1,CASP9,ELK1,FOS,BCAR1,ARF4,RASA1,SOCS3,PLCG1,JAK1,HDAC1,PIK3C2B,KLF11,PITPNA,PLD1,GAB1 |
| 8.675e-04 | -7.05 | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | 305 | 48 | 17758 | 1761 |
GCLM,TXN,ADD1,PPP1R2,DLGAP5,FOXM1,PSME2,IQGAP1,KIF23,SELL,NKRF,CCNB1,OAT,COX6C,STIL,LBR,TOP2A,KIF14,AIM1,NEK2,PLK4,TUBG1,SGK1,CD70,AHCY,OSTF1,MYO5A,CKS2,HMMR,PPIF,CLCN3,CENPA,CDC20,GGH,ARHGDIB,CCNF,KIF11,CDK1,FAS,PRIM1,GALNT3,PRPS2,DBI,ATP1B3,CENPE,UBE2C,ESPL1,ACOT7 |
| 8.689e-04 | -7.05 | innate immune response | biological process | GO:0045087 | 1014 | 134 | 16441 | 1675 |
TXN,LGR4,NRG2,PSME1,ITPR2,PDGFB,SPTB,TRIM68,CALM2,PSMD1,RPS6KA2,SHC3,ELMO2,PIK3CA,IRF2,PIK3CD,APOBEC3G,RASGRP1,NLRP4,CD55,TRIM8,ITCH,USP18,CASP9,CR2,AGO4,PRKAR2B,F12,RNF19B,PLCG1,LIMK1,NOD2,F2RL1,GAB1,DDX58,LGALS3,HLA-E,RASA2,HLA-F,CALM3,NCKAP1,TEC,PHLPP1,RPL39,DAPK1,HLA-C,NCAM1,ULBP2,MICB,CALM1,ELK1,IFIT3,PSMA4,RASA1,MAPKAPK2,PELI2,PHLPP2,CSF1,RAET1L,ITPR1,NFKBIA,NLRC5,ARPC2,MAP3K5,JAK3,IFIH1,IFI6,TMEM173,SPRED1,NLRX1,PSME2,RPS6KA1,ERBB2,BCL2L1,PRKACA,PDGFA,APOBEC3B,SP100,PLCG2,CDKN1B,DAB2IP,OAS3,IFIT1,RASGEF1A,LGMN,FRS3,MX1,AKT1,APOBEC3D,RIPK2,PRKCQ,ITPR3,DUSP4,SOCS3,IRS2,DDOST,JAK1,AXL,NRG1,IRF7,SPTBN5,TNRC6C,HERC5,PSMD10,APOBEC3H,FGF19,HLA-A,CXCL16,ADRBK1,PTEN,TRIM21,ADAM15,MAPK11,ERBB3,CNPY3,TRIM62,SYK,RASGRF1,PSMB4,IFITM3,RAPGEF2,NR4A1,NUB1,PIK3R1,GRIN1,FBXO9,YES1,FOS,CTSL,HLA-B,FGFR2,DTX4,GRIN2D,GPER1 |
| 8.709e-04 | -7.05 | V$E47_01 | MSigDB lists | V$E47_01 | 242 | 40 | 17758 | 1761 |
IER5L,SCN5A,SORBS1,HOXB7,TRIP10,KLHL13,DDIT4L,THRA,ITGA6,CACNA2D2,GABRG2,CALM3,CAMK1D,PDGFB,PSIP1,CYP26A1,CALM2,ITGA3,SH3BP1,PLK4,DUSP10,EPB41L4B,CITED2,MYLIP,MAP3K3,DPYSL5,TRIM8,CORO2A,CALM1,RGAG1,GNA11,GNAS,ONECUT1,IDE,RBL1,CORO1C,NETO2,NR4A3,DRP2,DEF6 |
| 8.714e-04 | -7.05 | response to type I interferon | biological process | GO:0034340 | 73 | 17 | 16441 | 1675 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,IRF2,IRF7,HLA-C,OAS3,IFIT1,IFI6 |
| 8.721e-04 | -7.04 | regulation of protein localization to nucleus | biological process | GO:1900180 | 191 | 34 | 16441 | 1675 |
DDX58,TXN,NF2,NFKBIE,THRA,RAB23,PSMD10,TGFBR1,IL18,APC2,IL18R1,LMNA,NOV,CDH1,DACT1,BMP7,CABP1,DAB2IP,MDFIC,WNT3A,MDFI,CHP1,SIRT1,RHOA,TRIM8,AKT1,PIK3R1,LITAF,PRKCQ,CDK1,FZD7,NFKBIA,PKIA,TMEM173 |
| 8.739e-04 | -7.04 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 196 | 34 | 17758 | 1761 |
GAS2L1,CCNI,ADD1,TBC1D1,DAP,HEXB,AES,NKRF,SEPP1,DHRS3,ERP29,AIP,TFAP4,DOPEY2,LMO4,SIVA1,BDH1,CD9,ADAM15,CLIP2,KDELR1,ALDH2,ZWINT,TIMP2,S100A4,FURIN,H2AFV,MAN2A2,GDE1,PNPLA6,ZMIZ1,LTA4H,CBX7,PCSK5 |
| 8.739e-04 | -7.04 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | 196 | 34 | 17758 | 1761 |
PAPSS2,NQO1,ATP9A,FAM134A,PPFIBP2,FBXO6,HES2,AKIRIN1,ST5,RPS6KA2,CA2,RALGPS2,CNTRL,SH3BP1,RGS3,BCL6,ABCD1,CLIP2,NAGA,MX1,COL6A2,TIMP2,BSDC1,NCOA3,RPL12,COQ10A,ACVRL1,PRDM5,NR4A3,F2RL1,ST3GAL1,USF2,ABCG1,JARID2 |
| 8.739e-04 | -7.04 | ATACTGT,MIR-144 | MSigDB lists | ATACTGT,MIR-144 | 196 | 34 | 17758 | 1761 |
CCNE2,LGR4,ARFGEF1,ETS1,NRP2,APPBP2,TFAP4,SS18,HSF2,ALDH1A3,FOSB,AHCY,PIM1,PDE4D,ACSL4,SLC12A2,MYT1,CCDC88A,ATP2B1,NR3C1,PTPN9,PANK1,PPARA,FNDC3A,PTGFRN,SP4,NIN,CACHD1,NGFRAP1,CDK19,GLCCI1,LIFR,CPEB2,E2F8 |
| 8.746e-04 | -7.04 | LEE_SP4_THYMOCYTE | MSigDB lists | LEE_SP4_THYMOCYTE | 13 | 6 | 17758 | 1761 |
NR4A2,PDE4D,DUSP4,SERPINE2,SPRY2,IER3 |
| 8.889e-04 | -7.03 | BMI1_DN.V1_DN | MSigDB lists | BMI1_DN.V1_DN | 137 | 26 | 17758 | 1761 |
COL9A3,TRIM2,CDH22,S100A4,SH3BGRL,ESRP1,BLVRB,EPHA4,PDE5A,NDRG2,NENF,SEPP1,IDH1,FOS,CTNNBIP1,DCTN6,HS6ST1,SCNN1A,CA2,METTL7A,TFAP2A,CAB39,HOXB13,TSPAN1,IFI6,ISOC1 |
| 8.921e-04 | -7.02 | JACKSON_DNMT1_TARGETS_UP | MSigDB lists | JACKSON_DNMT1_TARGETS_UP | 75 | 17 | 17758 | 1761 |
BIN1,MX1,IGFBP6,IFIT3,PHLDA1,SOCS3,PDGFA,GATA2,CYR61,CSF1,ZFP36,IRF7,AHCY,IFIT1,HMGA1,ETV4,HSPB1 |
| 8.949e-04 | -7.02 | MARTINEZ_RB1_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_TARGETS_DN | 511 | 73 | 17758 | 1761 |
LTBP1,TRIM2,KLK10,FAM92A1,EPAS1,CRYM,ST14,THRA,PTTG1,FHDC1,PKP2,COL18A1,DDR1,PDGFA,NOV,GRHL1,SIVA1,ALDH1A3,SLC44A1,MYH14,ECE1,CTTN,MARCH2,EGLN3,SCARA3,CLCN3,MBP,CELSR2,CAPN6,SNTB2,PANK1,KIF1C,GLO1,ITPR3,FZD7,AGFG2,UNC5B,LASP1,COL9A3,SORT1,CDKN1C,KLHL13,ESRP1,DAP,SOX9,TNFRSF19,GSTP1,FZD6,SIRPA,NEO1,CTNNBIP1,DOPEY2,CYR61,ATP5H,IGFBP2,IGDCC4,NFE2L3,PDGFC,GCLC,MYBL2,LITAF,FOS,TP53INP2,NFIB,PTPRF,PITX2,PLOD2,PVRL2,CLIP4,ITGAV,LTBP2,SERPINB1,AHR |
| 8.953e-04 | -7.02 | ROVERSI_GLIOMA_COPY_NUMBER_UP | MSigDB lists | ROVERSI_GLIOMA_COPY_NUMBER_UP | 95 | 20 | 17758 | 1761 |
SYPL1,DDB2,BCAM,LRP4,NUB1,SLC35C1,GALNT7,MAPK8IP1,RHEB,MDK,PRKAG2,PTPRJ,PVRL2,FOSB,MADD,KLC3,TSPAN13,CRY2,SYT13,AHR |
| 8.963e-04 | -7.02 | JOHNSTONE_PARVB_TARGETS_1_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_1_DN | 56 | 14 | 17758 | 1761 |
PDGFA,MCTP1,SCOC,ITGB8,SHC3,PTGER4,LIMCH1,RELL1,DNAJB14,DSE,SLC12A2,LIFR,STEAP1,ATP10D |
| 8.963e-04 | -7.02 | AMIT_SERUM_RESPONSE_60_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_60_MCF10A | 56 | 14 | 17758 | 1761 |
IRS2,TGIF1,CTGF,ETS2,CYR61,PLK2,CALD1,BMP1,PTGER4,SGK1,NR4A2,CYBRD1,KLF7,FRMD4B |
| 8.963e-04 | -7.02 | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | MSigDB lists | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | 56 | 14 | 17758 | 1761 |
CCND1,TOP2A,PLK1,SERPINE2,CD63,PBK,CDC20,DBI,CD9,TAGLN2,FOS,CDK1,NIN,SULF2 |
| 8.988e-04 | -7.01 | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | MSigDB lists | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | 44 | 12 | 17758 | 1761 |
ARHGAP11A,TOP2A,SPC25,DEPDC1,FOXM1,RANBP1,CDC20,MYBL2,PLK4,AURKA,CCNB1,CDK1 |
| 9.027e-04 | -7.01 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2156 | 255 | 17775 | 1757 |
LTBP1,GAA,LGR4,HSPG2,CAMKK1,CPT2,TSC22D3,EPHA4,RET,FHDC1,PSME1,CAMK1D,MGAT5B,PLXNA1,SLC20A1,DAPK2,BTG3,WEE1,RPS6KA2,MUC4,ZFP36,SLC44A1,ANKFN1,FOSB,AOX1,PIK3CA,MARCH2,PACSIN1,TLN2,TIPARP,PLK1,THRB,ATL1,ING1,CD55,KIFC2,CELSR2,ACVR1C,PBK,CR2,SLC35C1,TNS1,ARFRP1,ROR1,SAV1,IDH1,SPNS3,ADRBK2,STK17B,COL12A1,TRIM9,ZNF114,KCNMB4,HPSE,MAP2,WIPI1,PLK2,P4HA2,LIMK1,FAM114A1,MADD,BMP1,DHTKD1,SP6,WBSCR27,PRKAA2,CDK17,FRMD4A,ZNF395,PEX6,KIF23,ADCK5,MERTK,BMP2K,DAZAP1,IGF1R,FRY,PIK3AP1,GATA2,FRAS1,NEK2,DAPK1,PRKG1,ADCK2,MAP3K9,ALPK1,PIM1,CACNA1D,MPHOSPH9,CCDC88A,GPR161,SNX7,EPB41L5,ADCK3,TESK1,PIP4K2C,STRADB,EIF2AK1,PDK3,PDIK1L,C3orf58,RANBP9,PRX,STK17A,GNAS,MMP15,MAPKAPK2,CACHD1,SCARB2,PLEKHH2,TJP3,SLC4A4,PHLPP2,ITGA7,CDCA5,NLRC5,ALPK3,AURKA,CDK18,LTBP2,DRP2,PER3,PLIN3,MAP3K5,SHROOM2,JAK3,TOB1,NRBP1,ADAMTS16,DOCK9,SLC2A4,NF2,ST14,NLRX1,GALNT12,IQGAP1,RPS6KA1,TP53,PKP2,TESK2,ERBB2,TDRKH,GRK6,FAM198B,LPIN3,PRKACA,DDR1,MUC16,PLK4,CDH3,DAB2IP,EPHB4,F2R,SCYL3,FRS3,CTH,MYO5B,MAP3K3,COL6A2,RIPK2,AKT1,COG2,SEPT6,SYNE2,KIF1C,SLC11A2,PRKCQ,PKMYT1,ITPR3,MAP3K6,ZNF469,EPHA10,PPP2R5A,POPDC3,JAK1,CDK19,PTK7,STK38,AXL,PNPLA6,SLC27A1,ANXA9,MLKL,RGS14,SLC25A30,REEP4,COBL,MAPK12,DENND5B,BIN1,PINK1,GOLIM4,CDH22,ENO2,MACC1,PSMD10,TGFBR1,COL4A5,NOTUM,PKN1,TRIB2,SBF1,DNAH3,AIP,HMGXB4,NRP2,SIX4,SNTA1,IRF2BPL,TMEM87B,FUT2,ADRBK1,SLC27A6,CDK16,PTEN,SGK3,TFAP2A,ADAM15,SLC44A2,SGK1,ABCD1,MAPK11,BUB1,ERBB3,SYK,TPCN1,IGDCC4,NFE2L3,RASGRF1,B3GNT2,NR3C1,PIK3R1,CXorf57,FURIN,COL7A1,YES1,KIF11,GPLD1,SERPINA1,FAT4,C2orf70,ACVRL1,FGFR2,TMC5,NETO2,PGM2L1,UACA,ESPL1,HIPK3,L1CAM,RAB3IL1,MELK,OCLN,TLL2,DIS3L |
| 9.050e-04 | -7.01 | positive regulation of protein serine/threonine kinase activity | biological process | GO:0071902 | 290 | 47 | 16441 | 1675 |
AVPI1,IQGAP1,EPHA4,CALM3,PSMD10,ERBB2,PKN1,PDGFB,STIL,ERP29,CARD10,GRM5,CALM2,CCND1,PDGFA,MAP3K9,DAB2IP,MAPK11,MDFIC,PIM1,IQGAP3,SYK,SPRY2,DVL2,RASGRP1,MDFI,SIRT1,RIPK2,AKT1,FZD4,RAPGEF2,CALM1,RGCC,PDE5A,CD40,CDK1,MAP3K6,CDK5R1,MAPKAPK2,MADD,NOD2,ARRB1,CAB39,SLC27A1,FZD5,MAP3K5,GAB1 |
| 9.056e-04 | -7.01 | peptidyl-tyrosine modification | biological process | GO:0018212 | 155 | 29 | 16441 | 1675 |
RIPK2,TESK1,IL15,EPHA4,RET,TESK2,ERBB2,EPHA1,ROR1,TEC,YES1,PDGFB,DDR1,MERTK,EPHA10,WEE1,JAK1,IGF1R,FGFR2,AXL,PTK7,TPST1,RYK,MAP3K9,EPHB4,F2R,JAK3,SYK,MELK |
| 9.061e-04 | -7.01 | FRS-mediated FGFR1 signaling | REACTOME pathways | R-HSA-5654693 | 229 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 9.061e-04 | -7.01 | FRS-mediated FGFR2 signaling | REACTOME pathways | R-HSA-5654700 | 229 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 9.061e-04 | -7.01 | FRS-mediated FGFR4 signaling | REACTOME pathways | R-HSA-5654712 | 229 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 9.061e-04 | -7.01 | FRS-mediated FGFR3 signaling | REACTOME pathways | R-HSA-5654706 | 229 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 9.071e-04 | -7.01 | CTTTGCA,MIR-527 | MSigDB lists | CTTTGCA,MIR-527 | 227 | 38 | 17758 | 1761 |
CPEB4,KLHL13,MIER3,AKIRIN1,DAPK2,PTEN,ZNRF2,CALD1,FAM13B,ENPP5,ANKRD12,CCDC82,RP2,ACSL4,EPB41L4B,MYLIP,SMARCA2,TACC1,FZD4,SEPT6,FOXJ2,UBE2A,RUNX3,FNDC3A,PTGFRN,DAG1,CRISPLD2,SOCS3,KLF12,SYT7,STK38,CORO1C,GNPTAB,SFMBT1,NR4A2,ARPC2,CBX7,NR3C2 |
| 9.079e-04 | -7.00 | ETSDOMAIN | prints domains | PR00454 | 28 | 9 | 4759 | 462 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7,ELF3 |
| 9.096e-04 | -7.00 | INSP3RECEPTR | prints domains | PR00779 | 3 | 3 | 4759 | 462 |
ITPR2,ITPR3,ITPR1 |
| 9.096e-04 | -7.00 | NUCLEARECPTR | prints domains | PR01284 | 3 | 3 | 4759 | 462 |
NR4A2,NR4A1,NR4A3 |
| 9.117e-04 | -7.00 | BURTON_ADIPOGENESIS_7 | MSigDB lists | BURTON_ADIPOGENESIS_7 | 50 | 13 | 17758 | 1761 |
CCND1,TIMP2,NQO1,SERPINE2,IFITM3,IL6ST,S100A4,PBX3,TAGLN2,TINAGL1,CTTN,H2AFV,S100A6 |
| 9.117e-04 | -7.00 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | 50 | 13 | 17758 | 1761 |
CD99,COL6A2,FAM92A1,TNIP1,NUAK1,SCG2,ZCCHC24,UTRN,STRADB,RNF182,LOXL2,ARHGEF40,SEMA3A |
| 9.123e-04 | -7.00 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 43 | 12 | 16441 | 1675 |
PPIF,PINK1,BMF,AKT1,DNM1L,PLAUR,TP53,BAX,PSMD10,GPER1,BCL2L1,LMNA |
| 9.125e-04 | -7.00 | carbohydrate derivative biosynthetic process | biological process | GO:1901137 | 656 | 92 | 16441 | 1675 |
SLC35D2,ACACB,SLC2A4,UGT8,PAPSS2,HSPG2,UGP2,GALNT12,SLC25A13,XYLT1,NANS,MGAT5B,SDC1,PHLDA1,CHPF,TYMP,MUC16,MUC4,XYLT2,PAPSS1,FUT1,RPN2,LMAN1,TIPARP,MGAT5,SIRT1,SEC23A,TNIP1,PANK1,CDA,GALNT7,MCFD2,ARF4,MAN2A2,HS6ST1,DDOST,DOLPP1,GNPTAB,SLC27A1,HS3ST3B1,ST3GAL1,NDST3,CMAS,SDC4,GNE,PDIA3,CTSZ,B4GALT4,DSE,POMGNT1,ADAMTSL4,B4GALNT1,B3GALNT1,FUT2,CTSC,A4GALT,ATP5H,MGAT4A,ALG13,FUT8,UBE2J1,PPP6R1,GCNT1,TRAK2,CHSY3,GFPT1,B3GALT6,B3GNT7,B3GNT2,SHMT1,PLSCR1,PQLC3,PLAUR,MGAT4B,GYLTL1B,PARP4,AK4,C1GALT1C1,COL7A1,FOXL1,GLCE,GNAS,FUCA1,GALNT3,PRKAG2,UAP1,SERPINA1,DCK,PRPS2,CTSA,CMPK2,ACOT7 |
| 9.154e-04 | -7.00 | DER_IFN_BETA_RESPONSE_UP | MSigDB lists | DER_IFN_BETA_RESPONSE_UP | 102 | 21 | 17758 | 1761 |
MX1,PLSCR1,IQGAP1,HLA-E,PLAUR,PARP4,TAP1,PSME1,IFIT3,PHLDA1,HLA-A,ATP6V0B,ETS2,PLOD2,CALD1,NMI,IRF2,TRIM21,IFIT1,HLA-C,IFI6 |
| 9.158e-04 | -7.00 | neural crest cell development | biological process | GO:0014032 | 67 | 16 | 16441 | 1675 |
SEMA6B,HES1,RET,SOX9,EFNB1,FGF19,EDNRA,PITX2,SEMA4D,CORO1C,NRG1,TWIST1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 9.200e-04 | -6.99 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | 174 | 31 | 17758 | 1761 |
DDX58,MX1,REC8,TGIF1,PLSCR1,SPATA18,USP18,TAP1,NDC80,HERC5,SAMD9,CD274,IFIT3,HERC6,PRX,DTX3L,ZNF687,FAM46A,C19orf66,ANKS1B,NLRC5,RAB11FIP1,NR4A3,TRIM21,IRF7,IFIT1,OAS3,CMPK2,IFIH1,IFI6,PARP9 |
| 9.201e-04 | -6.99 | GSE17721_LPS_VS_POLYIC_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDM_DN | 189 | 33 | 17758 | 1761 |
LASP1,TM2D2,IL15RA,NDC80,GPSM2,MGST2,SDC1,ARHGEF40,LMNA,DOPEY2,WEE1,RGS3,CD9,DLG3,NAGA,RASGRF1,SUN2,TIMP2,SAT1,PLEKHO1,NFIB,PSMA4,STX3,LRRC42,UAP1,GPRC5B,PRCP,NAT1,ITPR1,ARF6,SERPINB1,RARG,E2F8 |
| 9.201e-04 | -6.99 | GSE3982_EOSINOPHIL_VS_DC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_UP | 189 | 33 | 17758 | 1761 |
RMND5A,ACACB,GOLIM4,SSH1,CNOT8,GRK6,KBTBD11,DNAH3,TEAD3,ZNF75D,PTEN,FLRT3,KLF3,PAPSS1,ESPN,CTDSP2,DLGAP1,CENPA,TACC1,SYNE2,KIF13A,PKMYT1,PCTP,STK17B,GABARAPL1,JAK1,WIPI1,AURKA,FAM117A,YOD1,EIF4EBP2,RGS14,JARID2 |
| 9.201e-04 | -6.99 | GSE27786_CD4_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_CD4_VS_CD8_TCELL_UP | 189 | 33 | 17758 | 1761 |
GAS2L1,WASF3,FBLIM1,PTTG1,TEX2,FBXO6,NUCB2,CDKN2C,ACAP2,IGF1R,GNB5,FRYL,CCDC82,TSPAN13,TIAM1,CTDSP2,ATP2B1,MYO5A,GPX4,ZNF462,GCA,PLSCR1,CORO2A,ZBTB7B,CASP4,H1F0,MAP2,FAAH,SLC9A6,ITGAV,ARPC2,TMEM173,ESYT2 |
| 9.201e-04 | -6.99 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 189 | 33 | 17758 | 1761 |
HLA-E,UBASH3B,ITGA6,TRIM68,BMP2K,TMEM63A,RPS6KA2,RUNDC3B,IFIT1,REC8,OXR1,PTGER4,TTC7A,KIF13A,RNPEP,KCTD2,CASP4,GNA11,HLA-B,PTPRJ,BANK1,NR1D2,TWSG1,PHLPP2,LRIG1,NLRC5,ABCB1,ARRB1,FGD6,ARSB,CBX7,NR3C2,XDH |
| 9.201e-04 | -6.99 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | 189 | 33 | 17758 | 1761 |
CCNE2,RMND5A,GOLIM4,SERPINE2,GNPDA1,HLA-E,ARL4C,KIF23,BCL2L1,ITPR2,OAT,MNS1,TIPRL,BTG3,ECI2,LMAN1,CDKN2D,MDFI,CLCN3,SMARCA2,SEC23A,ASPM,MPP1,SPATA13,ANKRD10,CDKN2AIPNL,ETS2,DCK,CSTF2,SLC27A1,ISOC1,RRAGD,ABCG1 |
| 9.217e-04 | -6.99 | membrane microdomain | cellular component | GO:0098857 | 272 | 44 | 17570 | 1756 |
CASP3,SPRED1,SCN5A,SORBS1,SLC2A4,PACSIN2,NF2,RET,SDC4,LRP4,EFHD2,ERBB2,HDAC6,PRKACA,EMP2,EFNB1,CDH1,IGF1R,KCNN4,DLG1,TRPC1,PIKFYVE,F2R,LAMP2,CD55,PLSCR1,RGMB,FURIN,EZR,PRKAR2B,ATP1B1,DAG1,FAS,ATP1A1,HPSE,CORO1C,PRKCDBP,SLC27A1,EFNA5,ATP1B3,MAL2,UNC5B,ABCA1,PROM2 |
| 9.237e-04 | -6.99 | regulation of cell aging | biological process | GO:0090342 | 32 | 10 | 16441 | 1675 |
SIRT1,FOXM1,NUAK1,PTEN,BCL6,TP53,TWIST1,HMGA1,VASH1,LMNA |
| 9.237e-04 | -6.99 | positive regulation of establishment of protein localization to plasma membrane | biological process | GO:0090004 | 32 | 10 | 16441 | 1675 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,EZR,GPER1,ARF6,ARHGEF16 |
| 9.237e-04 | -6.99 | nitric oxide metabolic process | biological process | GO:0046209 | 32 | 10 | 16441 | 1675 |
CALM2,NQO1,AKT1,CALM1,CALM3,SLC7A2,SPR,POR,ZDHHC21,CYP1B1 |
| 9.251e-04 | -6.99 | positive regulation of cell migration | biological process | GO:0030335 | 369 | 57 | 16441 | 1675 |
SEMA6B,ANXA3,LGALS3,ATP8A1,SOX9,RET,COL18A1,SELL,CD274,CAMK1D,HDAC6,PDGFB,ETS1,FBLN1,SRPX2,NRP2,HDAC9,PDGFA,DAPK2,CXCL16,ITGA3,IGF1R,CYR61,DAB2IP,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,EPB41L5,DOCK4,SUN2,RHOA,AKT1,RAPGEF2,PIK3R1,ANO6,SYNE2,FURIN,EPHA1,DOCK5,BCAR1,GPLD1,IRS2,PLCG1,ONECUT1,SWAP70,SEMA4D,PLPP3,CSF1,FAM110C,ITGAV,GPER1,F2RL1,SEMA3A,HSPB1 |
| 9.331e-04 | -6.98 | ARHGAP32 (Rho GTPase activating protein 32) | protein interactions | 9743 | 41 | 12 | 16036 | 1726 |
PLCG1,RHOA,CDH1,NF2,AKT1,SHC3,PIK3R1,ARRB1,AES,BCAR1,GAB1,MDFI |
| 9.345e-04 | -6.98 | Cdk1 (cyclin-dependent kinase 1) | protein interactions | 12534 | 82 | 19 | 16036 | 1726 |
CDK17,CDKN1C,IQGAP1,EZR,PKMYT1,CCNB1,CDK1,ARF4,TYMP,WEE1,IDE,CA2,CDK16,CORO1C,POF1B,CDKN1B,CCNB2,ESPL1,CKS2 |
| 9.353e-04 | -6.97 | Role of phospholipids in phagocytosis | REACTOME pathways | R-HSA-2029485 | 26 | 9 | 8202 | 867 |
PLCG1,PLCG2,ITPR1,PIK3R1,PIK3CA,ITPR2,PLD1,ITPR3,SYK |
| 9.363e-04 | -6.97 | MYC_UP.V1_DN | MSigDB lists | MYC_UP.V1_DN | 152 | 28 | 17758 | 1761 |
PLK1,REC8,ATL1,LMTK3,BCL9,CDCA8,PBX3,IL18,SAMD9,PJA2,BCAR1,C11orf95,MAP3K6,SPNS3,HOXB2,SPTB,C16orf74,CPNE2,KLF12,GRHL1,LYPD3,FGD6,CCDC82,MTMR11,FBXO27,PTPRE,SERPINB1,CLIP2 |
| 9.369e-04 | -6.97 | Glycosaminoglycan metabolism | REACTOME pathways | R-HSA-1630316 | 123 | 25 | 8202 | 867 |
HMMR,CHSY3,B3GALT6,B3GNT7,SLC35D2,B3GNT2,PAPSS2,HSPG2,GUSB,SDC4,HEXB,DSE,B4GALT4,SDC1,CHPF,GLCE,GNS,HS6ST1,HPSE,PAPSS1,HS3ST3B1,ARSB,ST3GAL1,NDST3,CHP1 |
| 9.440e-04 | -6.97 | maintenance of location in cell | biological process | GO:0051651 | 93 | 20 | 16441 | 1675 |
SUN1,SUN2,GAA,PINK1,NFKBIE,AKT1,THRA,ASPM,SYNE2,EZR,PSMD10,PDIA3,FTH1,DAG1,NFKBIA,SORL1,SUN3,TLN2,KDELR1,MDFI |
| 9.449e-04 | -6.96 | V$PXR_Q2 | MSigDB lists | V$PXR_Q2 | 243 | 40 | 17758 | 1761 |
UGP2,HEBP1,XYLT1,ETV5,NDRG2,PSME1,DHRS3,PRKACA,SYTL2,ZDHHC21,SCNN1A,CTGF,ZCCHC12,CABP1,LMO4,VASN,PLCG2,FABP6,MITF,ATRNL1,ADAM15,MANF,ETV4,CCDC88A,HES1,BCL9,SAT1,TNS1,ATP1B1,PITX2,SLC6A6,NR4A3,OVOL1,ZDHHC7,NRG1,NR3C2,RARG,HOXC13,KLF7,NR2C2 |
| 9.485e-04 | -6.96 | negative regulation of protein import | biological process | GO:1904590 | 61 | 15 | 16441 | 1675 |
NOV,NFKBIE,THRA,BMP7,CABP1,NFKBIA,LITAF,RAB23,PSMD10,DAB2IP,MDFIC,APC2,PKIA,MDFI,CHP1 |
| 9.485e-04 | -6.96 | negative regulation of cyclin-dependent protein kinase activity | biological process | GO:1904030 | 61 | 15 | 16441 | 1675 |
PLK1,TFAP4,CDK5RAP1,CASP3,CDKN1C,PTEN,DNAJC3,CDKN1B,TRIB2,UBE2C,MAPK8IP1,PKIA,SOCS5,SOCS3,CHP1 |
| 9.485e-04 | -6.96 | negative regulation of protein import into nucleus | biological process | GO:0042308 | 61 | 15 | 16441 | 1675 |
NOV,NFKBIE,THRA,BMP7,CABP1,NFKBIA,LITAF,RAB23,PSMD10,DAB2IP,MDFIC,APC2,PKIA,MDFI,CHP1 |
| 9.505e-04 | -6.96 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 947 | 124 | 17570 | 1756 |
PLA2G4A,IL15RA,DNAJC3,XYLT1,PDIA5,TAP1,ITPR2,MGST2,PJA2,LPIN3,CYP39A1,BCAP31,CYP26A1,ABCD4,CDS1,CYP1A1,CYP4F11,STIM1,CYP2S1,XYLT2,REEP1,DLG1,RPN2,MARCH2,NOTCH3,ACSL4,TECR,LMAN1,SCARA3,PDIA6,TRAM1,RASGRP1,ERAP2,CYP1B1,MX1,ATL1,SEC23A,EVA1A,SEC61B,C3orf52,SYNE2,NFE2L1,PKMYT1,DNAJB14,ITPR3,MCFD2,ICMT,PTGFRN,TRIQK,CASP4,ATP10D,POR,CYP4F3,RHEB,TAPBP,DDOST,AGPAT2,DOLPP1,SLC9A6,WFS1,PNPLA6,SARAF,CYP2U1,PIEZO1,REEP4,NR3C2,SORT1,HLA-E,HLA-F,FXYD3,DHRS3,LBR,HLA-A,DNAJB9,SGPL1,FLRT3,ALG13,RRBP1,SUCO,BAX,UBE2J1,TMBIM6,SGK1,SELK,HLA-C,FAR2,ALDH3A2,CKAP4,KDELR1,FAM69A,CYP26B1,FADS2,RHOA,LPGAT1,PLAUR,AMFR,ELOVL3,EIF5A2,ERO1A,FURIN,EMC2,TXNDC11,SPTLC2,CPTP,MAPK8IP1,CYB5A,HLA-B,FAAH,PLOD2,PLPP3,MFSD2A,ITPR1,PGRMC1,ERAP1,GPER1,SPCS3,PLD1,PLOD3,MAP3K5,APOL2,PTGES,TMEM173,ABCG1,ESYT2 |
| 9.530e-04 | -6.96 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | 82 | 18 | 17758 | 1761 |
CENPA,KIF20A,DLGAP5,MYBL2,CDCA8,NUSAP1,FAM198B,KIF11,LBR,UBE2T,FAM64A,CDCA5,RANBP1,NEK2,RTKN2,E2F8,SEMA3B,SULF2 |
| 9.578e-04 | -6.95 | vacuolar membrane | cellular component | GO:0005774 | 320 | 50 | 17570 | 1756 |
LAMP1,MAN2B2,GAA,SORT1,CD63,TMEM55B,SLC36A4,TMEM63A,ABCD4,M6PR,MARCH8,ATP6V0B,PQLC2,AP1M2,ZNRF2,VASN,COL6A1,DRAM1,PCYOX1,ABCA2,SLC44A2,PLEKHF1,RPN2,ECE1,MARCH2,TSPAN1,TMEM9,TPCN1,LAMP3,LAMP2,EVA1A,MMD,IFITM3,OSTM1,LITAF,SLC11A2,GNA11,RHEB,GPLD1,GABARAPL1,ATP13A2,SCARB2,ENPP1,HPSE,WIPI1,ARRB1,CTSA,PLD1,STARD3NL,RRAGD |
| 9.587e-04 | -6.95 | regulation of leukocyte apoptotic process | biological process | GO:2000106 | 80 | 18 | 16441 | 1675 |
SIRT1,LGALS3,TSC22D3,RAPGEF2,TP53,PRKCQ,CD274,MERTK,IRS2,PTEN,AXL,BCL6,BAX,NR4A3,NOD2,IRF7,SLC39A10,JAK3 |
| 9.634e-04 | -6.95 | V$CIZ_01 | MSigDB lists | V$CIZ_01 | 220 | 37 | 17758 | 1761 |
HOXB7,CHCHD7,CAST,NRG2,INTS8,PDGFB,SYTL2,WWP2,CCND1,CDKN2C,FOXP2,FAM46A,STIM1,FLRT3,RIMS3,PDE4D,NCAM1,CCDC88A,CKAP4,IGSF3,LAMP2,SMARCA2,BCL9,PLEKHO1,PRICKLE1,C2orf69,NFIX,TMEM164,KLF12,NR4A2,CDK18,EFNA5,PPP2R3C,SEMA3A,TOB1,COL16A1,KLF7 |
| 9.636e-04 | -6.94 | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | MSigDB lists | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | 69 | 16 | 17758 | 1761 |
MMD,MPP1,ASAH1,EIF2AK1,PRKAR2B,SNN,ENDOD1,GNAS,MFAP3L,NGFRAP1,PGRMC1,CTSA,FHL1,GLA,CTTN,NRGN |
| 9.670e-04 | -6.94 | regulation of cyclic-nucleotide phosphodiesterase activity | biological process | GO:0051342 | 9 | 5 | 16441 | 1675 |
CALM3,CALM2,AIP,CALM1,EGLN1 |
| 9.670e-04 | -6.94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | biological process | GO:0002480 | 9 | 5 | 16441 | 1675 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 9.737e-04 | -6.93 | Nuc_orph_rcpt | interpro domains | IPR003070 | 3 | 3 | 18293 | 1814 |
NR4A2,NR4A1,NR4A3 |
| 9.737e-04 | -6.93 | InsP3_rcpt-bd | interpro domains | IPR000493 | 3 | 3 | 18293 | 1814 |
ITPR2,ITPR3,ITPR1 |
| 9.758e-04 | -6.93 | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 6295 | 682 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,AASS,DNAJC3,HEXB,RET,MMADHC,DHX8,FAM102B,DPP8,BARD1,FAM46C,CARD10,ZNF275,CDKN2C,PQLC2,CYP2S1,KLF3,TUBG1,SEMA3G,ACOX2,TINAGL1,RNF26,TIAM1,MGAT5,ERAP2,NWD1,SPEF2,SMARCA2,LOXL2,F12,CYP4F3,COL12A1,ABR,PLCG1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,FAM114A1,NOD2,AGFG2,MRPS28,RELL1,GAB1,SCN5A,ITGA6,RAB23,MERTK,HPCAL4,LMNA,RABGGTA,TFAP4,FRY,RIMS3,MEGF8,NEK2,NCAM1,DGKG,NUP85,MCCC2,HPS3,SLC37A1,KIF20A,NPHP3,TP53INP2,SPTLC2,DHX32,PTPRF,CACHD1,NCOA3,SLC4A4,SETD3,ITPR1,S100A5,CLMN,NDE1,TMEM173,RUSC1,XDH,DOCK9,ARHGAP11A,NQO1,ACTR8,PKP2,PRSS22,NUF2,IL13RA1,GRK6,APC2,REPS1,MUC16,ST5,SCNN1A,CDH1,DACT1,RASGEF1A,LRP11,MYT1,SCN3A,ENPP4,COL6A2,APOBEC3D,PTPN9,SYNE2,HTATIP2,CDCA2,XRCC6BP1,ZNF618,SHROOM3,WFS1,AXL,INPP4B,PLEKHG1,RGS14,MAPK12,CTHRC1,TNRC6C,ESRP1,OSGIN2,BTN3A1,CTSZ,PKN1,PLPPR4,BEX2,NEO1,DTX3L,ADD3,FUT2,ITGB8,IGSF9,ARSG,MGAT4A,CST3,FAM20B,KLC3,ADAM15,WWP1,SGCB,PARP9,AMOTL2,PVRL4,ADAMTS2,TACC1,RAPGEF2,PIK3R1,MRS2,ELOVL3,CXorf57,CNTNAP1,GALNT3,ACVRL1,CENPE,FHL1,DCBLD1,TLL2,TMEM131,CCNI,ILDR1,KIAA1462,EPHA4,CUL4B,ARFGEF1,NDC80,TEX2,NENF,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,SUSD2,CPNE2,MKRN3,IL6ST,PAPSS1,TMEM143,ABCA2,DUSP10,ANO4,S100A13,NEB,ZNF462,PLK1,CELSR2,STAU2,ARFRP1,ANLN,IDH1,LHFPL2,DZIP1L,OPTN,HS6ST1,PLCH1,MSL1,KLF12,WIPI1,MAP2,DOLPP1,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,GLCCI1,PRKAA2,RUNX2,HJURP,DNAJB2,ASAH1,NCKAP1,FBLN1,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,KIF13B,AHCY,FAR2,WNT3A,MPHOSPH9,ABCC1,CHSY3,BTNL9,PRX,H1F0,COL13A1,PHLPP2,ITGA7,NLRC5,LTBP2,ATP1B3,ZDBF2,CCNB2,UPF3B,FOXM1,TMX4,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,SYTL2,RAD23A,IER3,TTC21B,WDR44,PLCG2,BCL6,GLB1L2,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,CTDSP2,SULF2,SIRT1,TMTC1,AKT1,ACO1,DAG1,MYL12A,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,RBL1,ADAMTS14,AIFM3,CMTM4,MAN2B2,BIN1,PINK1,PACSIN2,GOLIM4,CDH22,CPEB4,CD63,KLHL13,MACC1,RUSC2,ERI2,GTF3A,CRABP2,PARM1,VPS26A,SLC9A2,PPP2R3A,NRP2,M6PR,CD109,FOXP2,CDK16,TRIM21,BUB1,ALDH7A1,KLF9,TLE6,ATP2B1,NFE2L3,DLGAP1,HMMR,FBLN5,GUSB,AMFR,PPARA,MAML2,COL7A1,RNPEP,TXNDC11,BCAR1,MAPK8IP1,BSDC1,PRDX4,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,TBC1D4,HIPK3,GOLGB1,DIS3L,GAA,TTC39B,HSPG2,SSH1,LGR4,TSC22D3,PPFIBP2,PLXNA1,CCNB1,PJA2,SLC20A1,CENPN,CYP1A1,ANKS6,CTGF,ZNF823,IL31RA,SERINC2,PIK3CA,KCNS3,AOX1,SNX16,IRF2,ATRNL1,IQCD,HYLS1,SMYD5,ACVR1C,SNTB2,PBK,HSPA12A,SLC35C1,KIF13A,TNS1,GALNT7,CCNF,TP53I3,POR,GNPTAB,LRIG1,BMP1,PRDM5,DHTKD1,WBSCR27,UNC5B,TANC2,FGD1,DDX58,MRC2,FRMD4A,TBC1D1,DGKQ,KIF23,SLC1A3,TNFRSF19,KIAA1161,MECOM,DOPEY2,ITGA3,LYPD3,BDH1,DAPK1,SORL1,OSTF1,CD70,CACNA1D,PIKFYVE,GPR161,SOCS5,IGSF3,KCNJ12,PRODH,TBC1D8B,PIP4K2C,ATP8B3,ANTXR1,NFIB,GLT8D2,FRMD4B,PRKAG2,PLEKHH2,TJP3,FAM64A,MATN2,SLC4A3,FGD6,SFMBT1,CABIN1,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,PLA2G4A,MFSD3,SLC2A4,TCTN2,REPS2,ARMCX3,TRIP10,IQGAP1,RALBP1,RPS6KA1,CCDC110,ATP2C2,RNF182,FTH1,CD274,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,APLP2,TRANK1,DOK4,CNNM4,PDE4D,PHKA2,LGMN,GPX4,MYO5B,DOCK4,SEC23A,COG2,FOXJ2,PANK1,UTRN,KIF1C,PRKCQ,PYGO1,C15orf39,ITPR3,H2AFV,ATP10D,FZD7,NIN,EPHA10,PPP2R5A,SLC27A1,NRG1,MLKL,SLC27A3,COBL,DEPDC1,CCNJL,HERC5,CYB561,APOBEC3H,DNAH3,FGF19,EFNB1,TMCC3,RASSF8,E2F7,PHF7,PTEN,SGK3,CD9,CCDC82,TRIM62,OSGIN1,NCOA2,FARP2,PDGFC,TGIF1,ALDH2,ARHGEF28,B3GNT2,ARAP2,LONRF3,MPP1,ZKSCAN2,FURIN,PARP4,C2orf69,FOS,DCTN6,CDK5RAP1,MAMDC4,FGFR2,ABCB1,ERAP1,CSTF2,CCDC69,GRIN2D,WDR62,SLC25A38,NCAPG2,ESPL1,MELK,JARID2,RGMA,EXPH5,EMX1,LTBP1,CPT2,CAMKK1,KREMEN1,TMC1,DENND2D,SH3KBP1,HTR1D,NKAIN3,ZFYVE16,ARHGEF10L,SIPA1L2,DPYSL2,ANKFN1,PHTF1,DLG1,ANKRD12,TRPC1,SUN3,MYH14,SLC39A10,TECR,PTPRE,BTBD3,RASGRP1,CYP1B1,ATL1,RGAG1,MAN2A2,ZNF114,ARHGEF19,NEIL1,GPRC5B,MADD,ZNF165,ADIPOR1,CPPED1,PCSK5,STARD3NL,ZNF395,SERPINE2,LRRFIP2,PEX6,BVES,ETV5,ABCG2,FAM81A,PHLPP1,ADAMTSL4,ZNF432,CA2,KCNN4,COL6A1,LIMCH1,HLA-C,C10orf54,NCEH1,SLC12A2,CCDC88A,ELK3,PODXL2,GYLTL1B,PDE5A,NUBP1,C3orf58,AMDHD1,STEAP1,RANBP9,MFSD7,GLCE,GNAS,XKRX,ONECUT1,SLC6A6,RHOBTB2,ALPK3,EGFL7,AFAP1,RARG,CCNE2,NCKAP5,FAM92A1,MORC4,COL18A1,IL27RA,ARHGEF16,LRRC45,SS18,ZNF687,SETDB2,FRYL,RPN2,EPB41L4B,ECE1,SCYL3,SEPHS1,PTPRU,ERBB2IP,CD40,DOCK5,ARHGAP35,BHLHB9,TLE1,SPTBN5,CYP2U1,REEP4,ABCA1,LIFR,GLIS3,FBLIM1,ENO2,ARHGEF11,FRMD6,ARMC7,LRP4,FAM134A,COL4A5,INTS8,NTAN1,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,GALNS,RRBP1,ARVCF,IQGAP3,RBMS2,MYO5A,PGM1,SUN2,PHF20L1,RAB3B,ASPM,NR4A1,RC3H2,SYBU,OGDHL,C2orf70,RND3,PRCP,DHRS2,OTUB2,UACA,ZMIZ1,SOX8,L1CAM,RAB3IL1,SNPH |
| 9.764e-04 | -6.93 | protein tyrosine kinase activity | molecular function | GO:0004713 | 142 | 27 | 16491 | 1673 |
RIPK2,TESK1,RET,EPHA4,TESK2,ERBB2,TEC,YES1,ROR1,EPHA1,MERTK,DDR1,NRP2,EPHA10,WEE1,IGF1R,JAK1,FGFR2,PTK7,AXL,MAP3K9,RYK,ERBB3,EPHB4,JAK3,SYK,MELK |
| 9.782e-04 | -6.93 | organonitrogen compound catabolic process | biological process | GO:1901565 | 346 | 54 | 16441 | 1675 |
HSPG2,ALDH6A1,AASS,CRYM,HAL,BLVRB,HEXB,SDC4,APOBEC3H,OAT,SDC1,SGPL1,GNS,TYMP,GALNS,PCYOX1,ALDH7A1,GOT1,AHCY,ECE1,PDE4D,GAD1,NAGA,APOBEC3G,GM2A,MCCC2,ERAP2,FAH,CHP1,CTH,HMMR,ENPP4,PRODH,SHMT1,GUSB,SAT1,CDA,PDE5A,BLVRA,RNPEP,AMDHD1,FUCA1,NUDT16,NEIL1,ALDH5A1,IDE,ACADSB,HPSE,ABHD12,ERAP1,GLA,ARSB,LTA4H,XDH |
| 9.788e-04 | -6.93 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | MSigDB lists | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 33 | 10 | 17758 | 1761 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP1B1,ATP1B3,ATP10D |
| 9.788e-04 | -6.93 | DORN_ADENOVIRUS_INFECTION_12HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_DN | 33 | 10 | 17758 | 1761 |
TOP2A,CCND1,H1F0,NFKBIA,SGK1,TNFRSF12A,COL7A1,CD83,IER3,ELF3 |
| 9.788e-04 | -6.93 | ROZANOV_MMP14_TARGETS_DN | MSigDB lists | ROZANOV_MMP14_TARGETS_DN | 33 | 10 | 17758 | 1761 |
SIGIRR,NOV,PIK3R1,SDC4,TRIOBP,PGM2L1,SNTB1,UBE2C,GAD1,EHD1 |
| 9.806e-04 | -6.93 | neuromuscular junction | cellular component | GO:0031594 | 50 | 13 | 17570 | 1756 |
SNTA1,SERPINE2,ITGA7,EPHA4,LRP4,DLG1,UTRN,PRKCQ,NRG1,COL4A5,PRKACA,F2R,CDK5R1 |
| 9.849e-04 | -6.92 | labyrinthine layer morphogenesis | biological process | GO:0060713 | 22 | 8 | 16441 | 1675 |
NCOA3,GRHL2,CYR61,FGFR2,ST14,SPINT2,FZD5,SOCS3 |
| 9.852e-04 | -6.92 | human chr6p23 | chromosome location | human chr6p23 | 12 | 5 | 26250 | 1887 |
RNF182,KIF13A,MCUR1,RANBP9,CD83 |
| 9.868e-04 | -6.92 | regulation of fatty acid oxidation | biological process | GO:0046320 | 27 | 9 | 16441 | 1675 |
IRS2,ACACB,PRKAG2,AKT1,PPARA,NR4A3,TWIST1,TYSND1,PLIN5 |
| 9.871e-04 | -6.92 | THIOREDOXIN_1 | prosite domains | PS00194 | 17 | 7 | 11866 | 1235 |
PDIA3,DNAJC10,TXN,PDIA6,TMX4,PDIA5,PDIA4 |
| 9.882e-04 | -6.92 | skin-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma | 506 | 72 | 17775 | 1757 |
KIAA1462,NF2,NQO1,EPHA4,RET,TP53,ERBB2,CAMK1D,DDR1,FAM46C,STIL,FANCI,CCND1,WEE1,CDH1,IL6ST,MITF,BCL6,PIK3CA,CDKN1B,NOTCH3,EPHB4,MYH14,TIAM1,ETV4,SZRD1,SMARCA2,RIPK2,AKT1,ERBB2IP,IDH1,FANCE,JAK1,AXL,INPP4B,TRAF5,LIFR,ESRP1,ETV5,ABCG2,PSIP1,SIX4,HLA-A,NRP2,BMP2K,IGF1R,PTEN,MAP3K9,SGK3,ATP8B1,SGK1,BUB1,HLA-C,ERBB3,PIM1,SYK,PDGFC,DDB2,PIK3R1,AMER1,MAML2,FOXL1,FAS,GNAS,HLA-B,FGFR2,NFKBIA,ABCB1,AURKA,MAP3K5,JAK3,AFAP1 |
| 9.901e-04 | -6.92 | Beta-catenin independent WNT signaling | REACTOME pathways | R-HSA-3858494 | 144 | 28 | 8202 | 867 |
TNRC6C,RHOA,PSMB4,FZD4,PSME2,CALM1,PRICKLE1,PSMD10,CALM3,AGO4,TCF7,SCRIB,PSME1,ITPR2,ROR1,ITPR3,PSMA4,FZD6,FZD7,CALM2,PSMD1,GNB5,ITPR1,PRKG1,RYK,FZD5,PLCB2,DVL2 |
| 9.907e-04 | -6.92 | regulation of Wnt signaling pathway | biological process | GO:0030111 | 299 | 48 | 16441 | 1675 |
CTHRC1,LGR4,PSME2,SOX9,LRP4,PSMD10,AES,PSME1,NOTUM,APC2,KREMEN1,HMGXB4,FZD6,PPP2R3A,CTNNBIP1,CCND1,PSMD1,RNF220,ITGA3,DACT1,DAB2IP,MDFIC,DIXDC1,ZRANB1,WNT3A,DVL2,MDFI,SULF2,PSMB4,ASPM,AMER1,PRICKLE1,NPHP3,PSMA4,FOXL1,ANKRD10,CXXC4,GPRC5B,FGFR2,ANKRD6,PLPP3,TBX18,NKD1,TRABD2A,TLE1,LRRK1,FZD5,RNF146 |
| 9.916e-04 | -6.92 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 7783 | 831 | 17775 | 1757 |
HECA,ACACB,ADD1,IL15RA,AASS,DNAJC3,HEXB,RET,MMADHC,DHX8,FAM102B,DPP8,BARD1,FAM46C,CARD10,ZNF275,CDKN2C,PQLC2,CYP2S1,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,RNF26,TIAM1,MGAT5,ERAP2,NWD1,SPEF2,SMARCA2,LOXL2,F12,CYP4F3,COL12A1,ABR,PLCG1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,FAM114A1,NOD2,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,E2F8,SCN5A,FAM169A,ITGA6,RAB23,MERTK,FAM21C,HPCAL4,LMNA,ELF3,RABGGTA,TFAP4,FRY,PAIP2B,RIMS3,MEGF8,NEK2,MAP3K9,PANX2,ZMYM1,NCAM1,DGKG,NUP85,MCCC2,HPS3,SLC37A1,KIF20A,NPHP3,TP53INP2,SPTLC2,PLIN5,DHX32,PTPRF,CACHD1,NCOA3,SLC4A4,SETD3,ITPR1,S100A5,CLMN,NDE1,TMEM173,RUSC1,XDH,ADAMTS16,DOCK9,ARHGAP11A,GRHL2,NQO1,GALNT12,ACTR8,PKP2,PRSS22,NUF2,IL13RA1,GRK6,APC2,TNFSF9,REPS1,MUC16,ST5,SCNN1A,CDH1,SP100,DACT1,RTKN2,RASGEF1A,LRP11,MYT1,SCN3A,ENPP4,COL6A2,APOBEC3D,FZD4,PTPN9,SYNE2,HTATIP2,CDCA2,NUSAP1,XRCC6BP1,ZNF618,SHROOM3,CDK19,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PLEKHG1,RGS14,MAPK12,CTHRC1,TNRC6C,CKAP2,ESRP1,OSGIN2,BTN3A1,CTSZ,PKN1,PLPPR4,BEX2,NEO1,DTX3L,ADD3,FUT2,ITGB8,IGSF9,SLC27A6,CTSC,ARSG,MGAT4A,CST3,FAM20B,KLC3,FAM102A,ADAM15,WWP1,SGCB,TPCN1,MED22,PARP9,AMOTL2,PVRL4,ADAMTS2,TACC1,RAPGEF2,PIK3R1,ELOVL3,MRS2,GRIN1,CXorf57,SNTB1,CNTNAP1,GALNT3,RAB11FIP2,NR1D2,ACVRL1,CENPE,FHL1,DCBLD1,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,FAM199X,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,TEX2,NENF,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,SUSD2,CPNE2,SHC3,MKRN3,IL6ST,PAPSS1,TMEM143,ABCA2,DUSP10,ANO4,TLN2,S100A13,NEB,ZNF462,PLK1,CELSR2,STAU2,NFE2L1,ARFRP1,ANLN,IDH1,LHFPL2,DZIP1L,OPTN,KDM4D,MFAP3L,PLCH1,HS6ST1,MSL1,KLF12,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,ARRDC1,KLF11,PIK3C2B,GLCCI1,PRKAA2,RUNX2,HJURP,CHCHD7,DNAJB2,ASAH1,NCKAP1,FBLN1,IL18R1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,FRAS1,KIF13B,AHCY,FAR2,WNT3A,PLCB2,MPHOSPH9,CKAP4,ABCC1,CHSY3,BTNL9,RGMB,SCRIB,EIF2AK1,PRX,COQ10A,H1F0,COL13A1,PHLPP2,ITGA7,CSF1,NLRC5,LTBP2,ATP1B3,ZDBF2,CCNB2,NF2,UPF3B,FOXM1,TMX4,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,SYTL2,RAD23A,IER3,PDGFA,TTC21B,WDR44,PLCG2,SRR,BCL6,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,MINPP1,EGLN3,SCN2A,CTDSP2,DVL2,SULF2,SIRT1,CLCN3,TMTC1,AKT1,FIGNL1,ACO1,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,IDE,PTPRJ,RBL1,ADAMTS14,ANXA9,AIFM3,NDST3,CMTM4,MAN2B2,ZMAT1,BIN1,PINK1,PACSIN2,GOLIM4,CDH22,CPEB4,CD63,KLHL13,MACC1,RUSC2,ERI2,GTF3A,NKRF,CRABP2,PARM1,VPS26A,SLC9A2,PPP2R3A,NRP2,M6PR,CD109,FOXP2,ALPP,CDK16,TRIM21,BUB1,ALDH7A1,KLF9,TLE6,ATP2B1,NFE2L3,HMMR,DLGAP1,FBLN5,IFITM3,GUSB,AMFR,PPARA,MAML2,COL7A1,RNPEP,TXNDC11,BCAR1,MAPK8IP1,BSDC1,PRDX4,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NDFIP1,TBC1D4,PTGES,HIPK3,GOLGB1,DIS3L,LAMP1,GAA,SLC35D2,LGR4,TTC39B,HSPG2,SSH1,TSC22D3,PPFIBP2,PLXNA1,CCNB1,PJA2,SLC20A1,CENPN,CYP1A1,ANKS6,CTGF,ZNF823,STIM1,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,SNX16,IRF2,IQCD,HYLS1,TACSTD2,MTMR11,MARCH2,SMYD5,ACVR1C,SNTB2,PBK,HSPA12A,SLC35C1,KIF13A,TNS1,GALNT7,SAV1,CCNF,TP53I3,SPNS3,POR,PLK2,GNPTAB,LRIG1,BMP1,PRDM5,DHTKD1,TANC2,UNC5B,WBSCR27,FGD1,DDX58,SEMA6B,MRC2,CDK17,FRMD4A,TBC1D1,DGKQ,SLC25A27,KIF23,SLC1A3,TNFRSF19,KIAA1161,MESDC2,MECOM,DOPEY2,RALGPS2,ITGA3,LYPD3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,DAPK1,PRKG1,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,GPR161,SOCS5,IGSF3,EPB41L5,KCNJ12,PRODH,B3GNT7,MFI2,TBC1D8B,PIP4K2C,ATP8B3,ANTXR1,NFIB,GLT8D2,FRMD4B,DGKH,AP1AR,PRKAG2,PLEKHH2,TJP3,FAM64A,MATN2,SLC4A3,AGBL5,FGD6,SFMBT1,CABIN1,CDK18,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,MFSD3,PLA2G4A,SLC2A4,TCTN2,REPS2,ARMCX3,TRIP10,NLRX1,IQGAP1,RALBP1,RPS6KA1,CCDC110,ATP2C2,RNF182,FTH1,CD274,DDR1,AIFM2,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,APLP2,TRANK1,DOK4,CNNM4,PDE4D,LGMN,TSPAN1,PHKA2,SULT2B1,NR2C1,GPX4,MYO5B,DOCK4,SEC23A,COG2,CAPN6,FOXJ2,PANK1,UTRN,KIF1C,PRKCQ,PYGO1,ATP1B1,C15orf39,ITPR3,H2AFV,ATP10D,SP4,FZD7,NIN,EPHA10,PPP2R5A,DDOST,SLC27A1,NRG1,MLKL,SLC27A3,COBL,DENND5B,ARHGEF3,DEPDC1,CCNJL,HERC5,CYB561,APOBEC3H,DNAH3,EFNB1,FGF19,TEAD3,TMCC3,RASSF8,E2F7,PHF7,PTEN,SGK3,CD9,CCDC82,TRIM62,NCOA2,OSGIN1,FARP2,TGIF1,PDGFC,ALDH2,ARHGEF28,B3GNT2,ARAP2,ERMAP,LONRF3,ZC3H11A,MPP1,PARP4,ZKSCAN2,FURIN,C2orf69,YES1,FOS,DCTN6,CDK5RAP1,MAMDC4,ACADSB,FGFR2,ABCB1,ERAP1,CSTF2,CCDC69,GRIN2D,WDR62,SLC25A38,NCAPG2,ESPL1,MELK,JARID2,RGMA,EXPH5,EMX1,LTBP1,CRYM,CPT2,CAMKK1,VARS2,DNER,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,HTR1D,ARHGEF10L,NKAIN3,ZFYVE16,SIPA1L2,DPYSL2,ANKFN1,PHTF1,DLG1,ANKRD12,TRPC1,SUN3,MYH14,TECR,SLC39A10,PTPRE,BTBD3,RASGRP1,CYP1B1,ATL1,TRIM8,ITCH,RGAG1,ROR1,STK17B,MAN2A2,ZNF114,ARHGEF19,NEIL1,GPRC5B,MADD,ZNF165,ADIPOR1,SP6,CPPED1,STARD3NL,PCSK5,LASP1,PPP1R2,ZNF395,SERPINE2,LRRFIP2,PEX6,BVES,ETV5,ABCG2,FAM81A,PHLPP1,ADAMTSL4,ZNF432,AIM1L,CA2,KCNN4,COL6A1,LIMCH1,C10orf54,HLA-C,NCEH1,SLC12A2,CCDC88A,ELK3,PODXL2,GYLTL1B,PDE5A,NUBP1,C3orf58,AMDHD1,STEAP1,MFSD7,RANBP9,MUM1L1,GLCE,GNAS,XKRX,FECH,ONECUT1,SLC6A6,TMEM30A,CGREF1,ALPK3,RHOBTB2,EGFL7,TOB1,COL16A1,AFAP1,RARG,PROM2,CCNE2,LMO7,GAS2L1,NCKAP5,SORBS1,FAM92A1,MORC4,COL18A1,IL27RA,ARHGEF16,LRRC45,SS18,ZNF687,SETDB2,FRYL,REEP1,RPN2,EPB41L4B,ECE1,SCYL3,SEPHS1,PTPRU,GLO1,IGSF8,ERBB2IP,CD40,DOCK5,ARHGAP35,BHLHB9,SECTM1,TLE1,OVOL1,VSIG10,SPTBN5,CYP2U1,REEP4,ABCA1,LIFR,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,FRMD6,LRP4,ARMC7,FAM134A,COL4A5,INTS8,SBF1,NTAN1,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,RRBP1,GALNS,ARVCF,IQGAP3,MYO5A,RBMS2,PGM1,PHF20L1,SUN2,RAB3B,NR4A1,ASPM,RC3H2,SYBU,OGDHL,KLHL2,SWAP70,C2orf70,RND3,PRCP,DHRS2,OTUB2,UACA,ARRB1,ZMIZ1,PLOD3,SOX8,L1CAM,RAB3IL1,SNPH |
| 9.918e-04 | -6.92 | CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 205 | 35 | 17758 | 1761 |
WASF3,LASP1,PACSIN2,SORBS1,ARAP3,NF2,SSH1,KIF23,TESK2,MRAS,ARHGEF10L,KIF5B,AP1M2,KIF13B,DLG1,PRKG1,TUBG1,CCDC88A,SUN2,RHOA,EZR,ARHGDIB,NUSAP1,ANLN,KIF11,NUBP1,BCAR1,RASA1,MID1IP1,RND3,LIMK1,FGD6,ARF6,SHROOM2,FGD1 |
| 9.938e-04 | -6.91 | ANK1 (ankyrin 1, erythrocytic) | protein interactions | 286 | 21 | 8 | 16036 | 1726 |
SLC4A3,NBPF3,TGFBR1,ITPR3,TIAM1,HSPB1,SPTB,L1CAM |
| 9.938e-04 | -6.91 | CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2)) | protein interactions | 1028 | 21 | 8 | 16036 | 1726 |
CCNE2,CCND1,AKT1,RBL1,LIMK1,MYBL2,NR4A2,CDK1 |
| 9.940e-04 | -6.91 | WHITFIELD_CELL_CYCLE_M_G1 | MSigDB lists | WHITFIELD_CELL_CYCLE_M_G1 | 138 | 26 | 17758 | 1761 |
CEP70,VANGL1,PBK,PTTG1,HMG20B,GDF15,MORF4L2,ANTXR1,NCS1,RHEB,PDGFA,DCTN6,KIF5B,NCOA3,ST5,MSL1,GATA2,PLK2,OPN3,IFIT1,SLC39A10,PLIN3,LRIF1,BTBD3,AFAP1,LNP1 |
| 9.940e-04 | -6.91 | MODULE_122 | MSigDB lists | MODULE_122 | 138 | 26 | 17758 | 1761 |
CD99,COL9A3,COL6A2,SELL,COL18A1,IL18,COL4A5,ARHGDIB,COL7A1,ALCAM,EFNB1,COL12A1,NEO1,PTPRF,CNTNAP1,ITGA3,CTGF,CDH1,RND3,PTK7,COL6A1,CDH3,ITGAV,NCAM1,L1CAM,COL16A1 |
| 9.968e-04 | -6.91 | aryl hydrocarbon receptor complex | cellular component | GO:0034751 | 3 | 3 | 17570 | 1756 |
AHRR,AHR,AIP |
| 9.975e-04 | -6.91 | WNT_SIGNALING | MSigDB lists | WNT_SIGNALING | 89 | 19 | 17758 | 1761 |
FZD4,BCL9,AES,TCF7,PYGO1,KREMEN1,FZD6,FZD7,CXXC4,CTNNBIP1,CCND1,PITX2,CSNK1G1,NKD1,TLE1,DIXDC1,FZD5,WNT3A,DVL2 |
| 1.003e-03 | -6.90 | CAGGTA_V$AREB6_01 | MSigDB lists | CAGGTA_V$AREB6_01 | 736 | 99 | 17758 | 1761 |
AVPI1,TTC39B,GRHL2,REPS2,HEBP1,CAST,TEX2,IL13RA1,LYNX1,PRKACA,PDGFB,SH3KBP1,SLC9A7,CHPF,IER3,PDGFA,CDKN2C,ST5,SH3BP1,XYLT2,TSPAN6,LHX6,REEP1,SLC44A1,BCL6,KCNS3,MANF,MYH14,PDE4D,EGLN3,CLCN3,CAPN6,KIF1C,KIF13A,ERBB2IP,ICMT,CD40,ITPR3,LDB2,PTGFRN,RNF19B,NFIX,DPYSL3,PLEKHG6,ALDH3B1,RBM47,KCNK1,PTK7,DOLPP1,OVOL1,KLF5,NRG1,NRGN,NR3C2,E2F8,PRR15,CMTM4,CAPN1,ZNF395,LRRFIP2,ETV5,ASB9,FAM81A,DHRS3,TNFRSF19,S100A2,SIX4,SIRPA,TEAD3,FOXP2,FRY,ITGB8,LYPD3,GATA2,BMP7,PPP4R1,SGK3,TFAP2A,CACNA1D,NCAM1,SPRY2,MDFI,CYP26B1,PVRL4,PDGFC,ARAP2,TACC1,OXR1,NFIB,MUM1L1,PTPRF,PITX2,DBI,AGBL5,PGRMC1,FAM117A,MAP3K5,JARID2,DOCK9 |
| 1.010e-03 | -6.90 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | 190 | 33 | 17758 | 1761 |
UGP2,SDC4,OSR2,SGPL1,ITGB8,PTEN,PIK3AP1,SNX18,FJX1,GTF2F2,PIK3CD,NFE2L3,TRIM8,TNIP1,PLSCR1,CD40,RNF19B,PSMA4,MYL12A,STK17B,DCP2,SOCS3,NIN,PTPRJ,HNRNPH2,STK38,RAP2C,SLC2A6,ARRB1,NFKBIZ,IFIH1,EHD1,KLF7 |
| 1.010e-03 | -6.90 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 190 | 33 | 17758 | 1761 |
NFKBIE,IL15RA,IL15,FOXM1,ATP8A1,TAP1,BTN3A1,IL27RA,CD274,AIFM2,SCML1,SGPL1,M6PR,DTX3L,TYMP,DAZAP1,DRAM1,RFX5,MINPP1,RASGEF1A,ETV7,C9orf72,PPIF,NFE2L3,CENPA,FOXJ2,MICB,TYSND1,ADRBK2,SOCS3,SLC2A6,ERAP1,CCDC69 |
| 1.010e-03 | -6.90 | GSE14308_TH1_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH1_VS_INDUCED_TREG_UP | 190 | 33 | 17758 | 1761 |
IGFBP6,ERI2,C5orf30,PKP2,CAMK1D,CACNB4,AIP,LBR,TMEM87B,FAM46A,RINL,GALNS,FAM13B,REEP1,ANKRD12,LRIF1,SPRY2,MOSPD2,SH3BGRL,FAM133B,CASP4,TAPBP,PLCH1,KCNMB4,ACVRL1,SIPA1L1,ZNF704,PPM1H,NETO2,RHOBTB2,IRF7,SLC27A1,YOD1 |
| 1.010e-03 | -6.90 | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | 190 | 33 | 17758 | 1761 |
GAS2L1,EXPH5,LZTFL1,VANGL1,AK7,ATP9A,ESRP1,TDRKH,BCL2L1,CAMK1D,POMGNT1,SPTB,SYTL2,NEO1,ELF3,ZNF823,ZCCHC12,KCNN4,CEP78,ALDH7A1,GOT1,CTTN,ARMCX6,MED22,REC8,PKMYT1,CRISPLD2,LRRC42,STK39,SLC27A1,ACOT7,MAPK12,PCSK5 |
| 1.010e-03 | -6.90 | GSE3982_BCELL_VS_TH1_DN | MSigDB lists | GSE3982_BCELL_VS_TH1_DN | 190 | 33 | 17758 | 1761 |
ANXA3,MRC2,SPC25,IL15RA,DLGAP5,FOXM1,ATP9A,ZCCHC24,PTTG1,TAP1,BARD1,PDGFA,BTG3,ABCA2,KCNS3,BUB1,CTTN,SPRY2,CKS2,PLK1,PPIF,CORO2A,MPP1,AK4,STEAP1,OPTN,RBM47,TWSG1,SECTM1,AMMECR1,CLIP4,REEP4,ACOT7 |
| 1.010e-03 | -6.90 | GSE27786_NKCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_UP | 190 | 33 | 17758 | 1761 |
CASP3,SORT1,TXN,TGFBR1,DHRS3,VPS26A,RASSF8,TNS3,E2F7,RPS6KA2,CA2,FAM63A,ATRNL1,IRF2,ABCD1,MCCC2,FRS3,MAP3K3,MCTP1,ANLN,RNF19B,POR,RASGRP2,PRDX4,NIN,KLHL2,PPP2R5A,ABHD12,STK38,NFKBIZ,ADIPOR1,SERPINB1,JARID2 |
| 1.010e-03 | -6.90 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_DN | 190 | 33 | 17758 | 1761 |
HLA-E,ATP8A1,ABCG2,KCTD12,HMGN3,GPSM2,TAF1B,EFR3A,ZFP36,FUT8,KLF3,MDFIC,RFX5,SGCB,RASGRP1,TLE6,FARP2,ATG4D,AMOTL2,MPP1,BCL9,NUB1,FNDC3A,SAV1,CD83,NAT1,CSF1,SPINT2,TRIOBP,HDAC1,IRF7,ST3GAL1,TOB1 |
| 1.010e-03 | -6.90 | GSE14350_IL2RB_KO_VS_WT_TREG_UP | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_UP | 190 | 33 | 17758 | 1761 |
TPRN,GOLIM4,ARL4C,EFHD2,DSE,DPP8,DENND2D,ST5,EFR3A,MGAT4A,MITF,FAM102A,MDFIC,RCAN3,ALS2CL,SLC16A5,DDX59,OSGIN1,CTH,MBP,SLC37A1,PTPN9,BCL9,PRKCQ,NPC2,ITPR3,NFIX,TAPBP,PHLPP2,TRIOBP,NLRC5,RHOBTB2,ARSB |
| 1.010e-03 | -6.90 | peptidyl-proline hydroxylation | biological process | GO:0019511 | 13 | 6 | 16441 | 1675 |
EGLN3,P4HA2,P3H2,P4HA3,CRTAP,EGLN1 |
| 1.013e-03 | -6.89 | synapse | cellular component | GO:0045202 | 679 | 93 | 17570 | 1756 |
LAMP1,NF2,EPHA4,FBXO2,ERBB2,KCTD12,BCL2L1,PJA2,PRKACA,CACNB4,GRM5,NCS1,SH3KBP1,DACT1,CABP1,DPYSL2,DLG1,CTTN,TLN2,DLG3,PACSIN1,MYRIP,F2R,CLCN3,SNTB2,SEPT6,UTRN,PRKAR2B,PRKCQ,DAG1,ARF4,PIAS3,TRIM9,ATP1A1,DNM1L,MAP2,KCNK1,SLC9A6,SIPA1L1,NRG1,PRIMA1,ITPKA,RGS14,NRGN,LZTS1,SERPINE2,CPEB4,CALB2,EPS8,LRP4,GABRG2,COL4A5,SLC1A3,EFNB1,SRPX2,SNTA1,ADD3,ITGA3,ADORA1,IGSF9,ZNRF2,PTEN,CDK16,ANKS1B,RIMS3,FLRT3,CADPS2,RIMS2,DLGAP1,SYPL1,RAB3B,RAPGEF2,GRIN1,SCRIB,SNTB1,MAPK8IP1,CDK5R1,RASGRP2,GABRD,FGFR2,SYT7,ITGA7,ITPR1,NETO2,ARRB1,GRIN2D,GPER1,NDE1,ARPC2,CPEB2,L1CAM,RUSC1,SNPH |
| 1.018e-03 | -6.89 | IL6ST (interleukin 6 signal transducer) | protein interactions | 3572 | 36 | 11 | 16036 | 1726 |
KCNIP3,JAK1,PLAUR,IL6ST,IL31RA,PIK3R1,TLE1,ERBB2,ERBB3,LIFR,SOCS3 |
| 1.025e-03 | -6.88 | appendage morphogenesis | biological process | GO:0035107 | 149 | 28 | 16441 | 1675 |
CYP26B1,RUNX2,GRHL2,FMN1,SALL4,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,FGFR2,IMPAD1,BMP7,MEGF8,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,RARG,PCSK5 |
| 1.025e-03 | -6.88 | limb morphogenesis | biological process | GO:0035108 | 149 | 28 | 16441 | 1675 |
CYP26B1,RUNX2,GRHL2,FMN1,SALL4,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,FGFR2,IMPAD1,BMP7,MEGF8,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,RARG,PCSK5 |
| 1.026e-03 | -6.88 | collagen catabolic process | biological process | GO:0030574 | 74 | 17 | 16441 | 1675 |
COL9A3,ADAMTS2,MRC2,COL6A2,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,COL16A1 |
| 1.027e-03 | -6.88 | EIF4E_DN | MSigDB lists | EIF4E_DN | 96 | 20 | 17758 | 1761 |
LMO7,CD55,SORT1,TNIP1,IQGAP1,ESRP1,DENND2D,APPBP2,FRMD4B,PRDX4,EPDR1,FAS,FUCA1,SEMA4D,CTSC,PTER,TSPAN6,ALPK1,MAP3K5,CYP1B1 |
| 1.029e-03 | -6.88 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | 63 | 15 | 17758 | 1761 |
MX1,HLA-B,JAK1,IFITM3,HLA-F,USP18,IRF2,IRF7,IFIT1,OAS3,HLA-C,IFIT3,IFI6,HLA-A,SOCS3 |
| 1.030e-03 | -6.88 | regulation of cell-matrix adhesion | biological process | GO:0001952 | 87 | 19 | 16441 | 1675 |
EPB41L5,NF2,FMN1,PIK3R1,SDC4,UTRN,EPHA1,EMP2,RASA1,ONECUT1,PTPRJ,PTEN,ACVRL1,CSF1,CORO1C,BCL6,ADAM15,EFNA5,COL16A1 |
| 1.035e-03 | -6.87 | VERHAAK_GLIOBLASTOMA_NEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_NEURAL | 124 | 24 | 17758 | 1761 |
ENPP4,ANXA3,MBP,UGT8,MMD,REPS2,CRYM,LYRM1,NDRG2,TMEM144,MORF4L2,SEPP1,HPCAL4,ADD3,PPP2R5A,POPDC3,KCNK1,ANKS1B,SGK3,ATRNL1,ARRB1,SERPINI1,MDH1,ACSL4 |
| 1.038e-03 | -6.87 | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | 633 | 87 | 17758 | 1761 |
CASP3,SIGIRR,NF2,S100A11,CNOT8,TP53,COL18A1,FTH1,BCL2L1,TP53I11,BARD1,IER3,CDKN2C,BTG3,FABP6,FOSB,DLG1,BCL6,CDKN1B,IRF2,TWIST1,CDKN2D,SIRT1,ING1,DRAP1,SERTAD3,CDA,HTATIP2,ARHGDIB,GLO1,RAD17,PRKRA,SESN1,CDK1,ARHGAP35,SOCS3,MID1IP1,KLF12,HDAC1,TLE1,NRG1,IRF7,KLF11,GLA,ARF6,HSPB1,MAPK12,GLIS3,RUNX2,ARAP3,NFKBIE,CDKN1C,IGFBP6,NKRF,GSTP1,ETS1,CARD8,IGF1R,PTEN,PAIP2B,BMP7,BAX,ATP8B1,WWP1,PIM1,OSGIN1,MDFI,SOCS5,TGIF1,ELK3,GCLC,FURIN,RUNX3,EIF2AK1,NPHP3,RASA1,FAS,CDK5RAP1,SEMA4D,SCG2,ACVRL1,DHRS2,CGREF1,IFI6,TOB1,HIPK3,CD33 |
| 1.040e-03 | -6.87 | REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_KINASE_ACTIVITY | 153 | 28 | 17758 | 1761 |
CCNE2,SPRED1,CDKN1C,ERBB2,STRADB,HERC5,PKMYT1,PKN1,TRIB2,MAP3K6,CARD10,CDK5R1,CDK5RAP1,DIRAS3,CCND1,CDKN2C,PTEN,RBL1,RGS3,MADD,MAP3K9,MDFIC,MAP3K5,CDKN2D,HIPK3,CCDC88A,MDFI,CKS2 |
| 1.042e-03 | -6.87 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | molecular function | GO:0005220 | 3 | 3 | 16491 | 1673 |
ITPR2,ITPR3,ITPR1 |
| 1.042e-03 | -6.87 | TAP2 binding | molecular function | GO:0046979 | 3 | 3 | 16491 | 1673 |
TAPBP,HLA-F,TAP1 |
| 1.042e-03 | -6.87 | N-terminal myristoylation domain binding | molecular function | GO:0031997 | 3 | 3 | 16491 | 1673 |
CALM3,CALM2,CALM1 |
| 1.045e-03 | -6.86 | CH-domain | interpro domains | IPR001715 | 76 | 17 | 18293 | 1814 |
GAS2L1,LMO7,CAMSAP3,SPEF2,ASPM,IQGAP1,SYNE2,UTRN,SPTB,PLS3,SMTNL2,CLMN,LIMCH1,DIXDC1,SPTBN5,TAGLN2,IQGAP3 |
| 1.048e-03 | -6.86 | central_nervous_system-thalamus-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-oligodendroglioma_Grade_III | 39 | 11 | 17775 | 1757 |
MYO5B,PLEKHG6,HS6ST1,PARP12,JAK1,TP53,PDE5A,FZD5,TIAM1,ABCA1,PCSK5 |
| 1.048e-03 | -6.86 | epithelioid | COSMIC cancer mutations | epithelioid | 39 | 11 | 17775 | 1757 |
LRRC45,PLCG1,SS18,CDH1,AKT1,PTEN,PIK3CA,TP53,IDH1,GNA11,TLL2 |
| 1.049e-03 | -6.86 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 198 | 34 | 17758 | 1761 |
GRN,SPRED1,IQGAP1,UBASH3B,TMX4,FBXO2,CACNA2D2,ASAH1,FAM102B,PBX3,TGFBR1,DDR1,FAM46C,BMP2K,MGAT4A,OSBPL3,TOX2,SGK1,TSPAN13,KLF9,CTTN,TIAM1,ALDH3A2,MGAT5,ELK3,GCLC,SLC39A8,PIK3R1,FNDC3A,PGF,PLCG1,MSL1,TMEM30A,CENPE |
| 1.049e-03 | -6.86 | KYNG_DNA_DAMAGE_UP | MSigDB lists | KYNG_DNA_DAMAGE_UP | 221 | 37 | 17758 | 1761 |
LRRFIP2,SOX9,CTDSPL,ERBB2,SLC1A3,RAB6A,CRABP2,PHLDA1,FBLN1,IL18R1,CYP39A1,NRP2,APPBP2,MECOM,SGPL1,ATP6V0B,HSF2,KIF14,ENPP5,MITF,AHCY,SYK,GM2A,ABCC1,CKS2,MYO5B,SEC23A,PCDH1,GCLC,EPHA1,PTGFRN,CYB5A,KCNK1,SLC9A6,GDF11,CYBRD1,PCSK5 |
| 1.054e-03 | -6.86 | regulation of phosphatase activity | biological process | GO:0010921 | 128 | 25 | 16441 | 1675 |
CAMSAP3,SPRED1,LMTK3,PPP4R4,PPP1R2,NUAK1,CALM1,CALM3,PKMYT1,TIPRL,SH2D4A,PPP2R3A,SYTL2,GPLD1,CALM2,PPP2R5A,NPNT,SEMA4D,CRY2,SLC39A10,DLG3,PPP2R2D,PPP6R1,ARFGEF3,CHP1 |
| 1.055e-03 | -6.85 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 422 | 62 | 17758 | 1761 |
LASP1,GGA1,RPS6KA1,TMEM41B,UBASH3B,CD82,EFHD2,NDUFA4,GTF3A,F11R,ITPR2,GRK6,KREMEN1,LBR,LTBP3,SIRPA,DAPK2,APLP2,MDM1,RPS6KA2,ADRBK1,GNB5,PTEN,PIK3AP1,PLCG2,TOX2,FOSB,TMEM143,RAB20,IQCD,TAGLN2,ECE1,PLCB2,NUP85,SULF2,SUSD3,PVRL4,B3GNT7,TIMP2,MBP,ALDH2,IFITM3,GUSB,CORO2A,PLEKHO1,MTRF1L,RUNX3,C15orf39,IDH1,RASGRP2,SLC6A6,PTPRJ,ITPR1,RAB11FIP1,ARRB1,UACA,HMGA1,ZMIZ1,SERPINB1,PTGES,TMEM173,DEF6 |
| 1.056e-03 | -6.85 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | biological process | GO:0002486 | 3 | 3 | 16441 | 1675 |
HLA-B,HLA-C,HLA-A |
| 1.056e-03 | -6.85 | Peyer's patch morphogenesis | biological process | GO:0061146 | 3 | 3 | 16441 | 1675 |
ARTN,FOXL1,RET |
| 1.056e-03 | -6.85 | courtship behavior | biological process | GO:0007619 | 3 | 3 | 16441 | 1675 |
THRB,THRA,HEXB |
| 1.056e-03 | -6.85 | somatic muscle development | biological process | GO:0007525 | 3 | 3 | 16441 | 1675 |
NEB,NKD1,PPP2R3A |
| 1.056e-03 | -6.85 | epithelial cell differentiation involved in embryonic placenta development | biological process | GO:0060671 | 3 | 3 | 16441 | 1675 |
GRHL2,ST14,SPINT2 |
| 1.056e-03 | -6.85 | negative regulation of helicase activity | biological process | GO:0051097 | 3 | 3 | 16441 | 1675 |
SIRT1,IFIT1,TP53 |
| 1.056e-03 | -6.85 | epithelial cell morphogenesis involved in placental branching | biological process | GO:0060672 | 3 | 3 | 16441 | 1675 |
GRHL2,ST14,SPINT2 |
| 1.061e-03 | -6.85 | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 168 | 30 | 17758 | 1761 |
LAMP1,PAPSS2,CDKN1C,SH3BGRL,S100A4,EPS8,LITAF,FAM102B,ASAH1,COL4A5,NPC2,DUSP4,ZFAND5,TNFRSF19,PSMA4,CMTM6,ZNF618,DZIP1L,ALDH3B1,FAM46A,PIK3AP1,CTSC,PLOD2,TWSG1,SNX18,CST3,SECTM1,NR4A3,ARPC2,ARF6 |
| 1.062e-03 | -6.85 | immune response | biological process | GO:0006955 | 1442 | 182 | 16441 | 1675 |
TXN,LGR4,AK7,TAP1,NRG2,PSME1,IL18,ITPR2,DPP8,PDGFB,SPTB,TRIM68,CALM2,SUSD2,PSMD1,RPS6KA2,SHC3,ELMO2,PIK3CA,DLG1,IRF2,TINAGL1,PIK3CD,S100A13,APOBEC3G,RASGRP1,ERAP2,LAMP3,NLRP4,CD55,TRIM8,ITCH,USP18,CASP9,CR2,AGO4,ARHGDIB,PRKAR2B,F12,PRKRA,RNF19B,ENPP1,PLCG1,LIMK1,NOD2,F2RL1,GAB1,DDX58,LGALS3,HLA-E,RASA2,HLA-F,CALM3,TEC,NCKAP1,PHLPP1,IL18R1,MARCH8,IGF1R,GATA2,RPL39,DAPK1,AHCY,CD70,HLA-C,NCAM1,ULBP2,MICB,CALM1,BTN3A2,TCF7,ELK1,IFIT3,PSMA4,RASA1,FAS,MAPKAPK2,SEMA4D,PELI2,PHLPP2,CSF1,NFKBIA,RAET1L,ITPR1,NLRC5,ARPC2,MAP3K5,IFIH1,JAK3,IFI6,TMEM173,SPRED1,NLRX1,IL15,INPP5D,RPS6KA1,PSME2,TP53,ERBB2,IL27RA,FTH1,CD274,BCL2L1,PRKACA,EMP2,TNFSF9,APOBEC3B,PDGFA,SP100,PLCG2,BCL6,CDKN1B,DAB2IP,IFIT1,OAS3,RASGEF1A,LGMN,FRS3,MX1,MBP,RIPK2,AKT1,APOBEC3D,PTGER4,PRKCQ,ITPR3,DUSP4,SOCS3,IRS2,TAPBP,DDOST,JAK1,AXL,SECTM1,NRG1,IRF7,SPTBN5,ANXA3,TNRC6C,BTN3A1,HERC5,PSMD10,APOBEC3H,ETS1,FGF19,HLA-A,CXCL16,ADRBK1,CTSC,PTEN,TRIM21,ADAM15,MAPK11,ERBB3,CNPY3,SYK,TRIM62,RASGRF1,PSMB4,IFITM3,RAPGEF2,NR4A1,PIK3R1,NUB1,RC3H2,GRIN1,RGCC,FBXO9,YES1,FOS,CD83,CTSL,HLA-B,SWAP70,FGFR2,DTX4,NR4A3,ERAP1,GRIN2D,GPER1,GEM,ICOSLG |
| 1.063e-03 | -6.85 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | 183 | 32 | 17758 | 1761 |
BIN1,LZTFL1,IGFBP6,TSC22D3,ATP2C2,IL18,TDRKH,PARM1,MARCH8,RPL39,ALG13,HLA-C,MPHOSPH9,CTDSP2,SCYL3,CRTAP,SMAGP,MAP3K3,TGIF1,NR3C1,TBC1D8B,SYNE2,CXorf57,TCF7,RASA1,MMP15,IRS2,HLA-B,RYK,INPP4B,CBX7,NR3C2 |
| 1.063e-03 | -6.85 | ZHANG_TLX_TARGETS_36HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_36HR_DN | 183 | 32 | 17758 | 1761 |
SPC25,UPF3B,DEPDC1,CUL4B,ERI2,KIF23,CENPN,PSIP1,HMGXB4,FANCI,TOP2A,FAM111A,PLK4,BUB1,EGLN3,SLC12A2,NUP85,CCDC88A,HMMR,SHMT1,FIGNL1,PIK3R1,NUSAP1,ANLN,KIF11,RASA1,PRIM1,SLC4A4,RBL1,TMEM30A,CENPE,NCAPG2 |
| 1.063e-03 | -6.85 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | 183 | 32 | 17758 | 1761 |
SUN1,LZTFL1,TSC22D3,PPFIBP2,KCTD12,SNN,TRIB2,DHRS3,LTBP3,SLC25A36,ADD3,A4GALT,DLG1,CRY2,KLF9,ECE1,PHKA2,MYLIP,DVL2,SMAGP,XKR8,ALDH2,ADCK3,LITAF,FOXL1,RASGRP2,SCARB2,FAAH,ANKRD6,RYK,TCEAL4,HOOK1 |
| 1.063e-03 | -6.85 | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | 183 | 32 | 17758 | 1761 |
CDK17,SDC4,TGFBR1,HDAC6,PHLDA1,CMTM6,SUSD2,RINL,IMPAD1,MGAT4A,OSBPL3,TOX2,DLG1,PLEKHF1,TMEM64,SCARA3,F2R,C9orf9,CPD,NWD1,B3GNT7,IFITM3,FURIN,PDE5A,SLC11A2,C3orf58,HLA-B,SLC4A4,KCNK1,PLEKHG1,HS3ST3B1,CPEB2 |
| 1.064e-03 | -6.85 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 81 | 18 | 16491 | 1673 |
LTBP1,ACVR1C,EPHA4,RET,ERBB2,TGFBR1,ROR1,EPHA1,MERTK,DDR1,NRP2,EPHA10,IGF1R,FGFR2,ACVRL1,AXL,RYK,EPHB4 |
| 1.066e-03 | -6.84 | vesicle membrane | cellular component | GO:0012506 | 452 | 66 | 17570 | 1756 |
SUN1,LAMP1,SLC2A4,IL15RA,ATP8A1,SYTL4,PHLDA1,APPBP2,SH3KBP1,ATP6V0B,AP1M2,N4BP3,RAB20,PACSIN1,LMAN1,RAB27B,MYRIP,SMAGP,LAMP3,MYO5B,LAMP2,SEC23A,CLCN3,FZD4,SNTB2,RAB38,MCFD2,GABARAPL1,ATP13A2,GPRC5B,RAB11FIP1,NRGN,ARFGEF3,ANXA3,PACSIN2,CD63,HLA-F,HLA-E,RAB23,FZD6,HLA-A,MARCH8,SNX18,ZNRF2,CD9,CADPS2,HLA-C,WNT3A,GAD1,GPR161,SNX7,KDELR1,SYPL1,RAB3B,ATP8B3,FNDC3A,C3orf58,HLA-B,RAB11FIP2,TMEM30A,ITPR1,ARRB1,GPER1,FZD5,TBC1D4,TMEM173 |
| 1.066e-03 | -6.84 | Ras GTPase binding | molecular function | GO:0017016 | 224 | 38 | 16491 | 1673 |
EXPH5,PIFO,RALBP1,RUSC2,IQGAP1,EPS8,SYTL4,NCKAP1,PKN1,ARHGEF16,SYTL2,RABGGTA,ACAP2,MLPH,LLGL2,RANBP1,EXOC8,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,STRADB,DIAPH2,RANBP9,OPTN,RAB11FIP2,CORO1C,SH3BP4,TRIOBP,RAB11FIP1,ITPKA,RAP1GAP,EHD1,DOCK9 |
| 1.076e-03 | -6.83 | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES | MSigDB lists | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES | 39 | 11 | 17758 | 1761 |
TAPBP,ATP1A1,ATP7B,ABCG2,ATP8B1,ATP1B1,ATP1B3,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 1.076e-03 | -6.83 | PENG_GLUTAMINE_DEPRIVATION_UP | MSigDB lists | PENG_GLUTAMINE_DEPRIVATION_UP | 39 | 11 | 17758 | 1761 |
TOP2A,MMP15,DDB2,PPP2R5A,NR3C1,BCL9,ITPR2,BARD1,PLCB2,RASA1,H1FX |
| 1.076e-03 | -6.83 | PID_AURORA_B_PATHWAY | MSigDB lists | PID_AURORA_B_PATHWAY | 39 | 11 | 17758 | 1761 |
CENPA,RHOA,KIF20A,KLHL13,TACC1,NDC80,CDCA8,KIF23,AURKA,BUB1,RASA1 |
| 1.081e-03 | -6.83 | endometrium-carcinoma-adenocarcinoma | COSMIC cancer mutations | endometrium-carcinoma-adenocarcinoma | 51 | 13 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.081e-03 | -6.83 | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | 57 | 14 | 17758 | 1761 |
CD109,COL9A3,TIMP3,COL6A2,CYR61,ITGA7,ZFP36,ATP8A1,FOSB,PPFIBP2,SORL1,NDRG2,ARVCF,MERTK |
| 1.083e-03 | -6.83 | cellular lipid metabolic process | biological process | GO:0044255 | 907 | 121 | 16441 | 1675 |
PLA2G4A,ACACB,MTM1,UGT8,HSPG2,CPT2,INPP5D,HEXB,TEX2,NANS,MGST2,LPIN3,PRKACA,SDC1,CYP26A1,CDS1,CYP1A1,CTGF,GRHL1,CYP2S1,IMPAD1,ALDH1A3,SLC44A1,FABP6,PLCG2,SERINC2,PIK3CA,PIK3CD,ACSL4,ACOX2,TECR,NAGA,GM2A,GPX4,CYP1B1,SIRT1,SLC35C1,PRKAR2B,IDH1,CYP4F3,POR,ALDH3B1,PLCG1,ALDH5A1,AGPAT2,ABHD12,DOLPP1,PEX2,INPP4B,PNPLA6,SLC27A1,ADIPOR1,PIK3C2B,CYP2U1,GLA,LTA4H,SLC27A3,ST3GAL1,ABCA1,PRKAA2,CMAS,FAM213B,TMEM55B,GNE,SDC4,ASAH1,ISYNA1,CRABP2,B4GALT4,PLPPR4,DHRS3,SGPL1,B4GALNT1,SLC27A6,ITGB8,ARSG,PTEN,A4GALT,ALG13,BDH1,BAX,SLC44A2,ECI2,ABCD1,PIKFYVE,FAR2,PLCB2,SYK,ALDH3A2,NCOA2,MYO5A,ABCC1,CYP26B1,GFPT1,FADS2,PLSCR1,PQLC3,PLAUR,LPGAT1,ELOVL3,PIK3R1,PIP4K2C,PPARA,RNPEP,SPTLC2,ARSK,CPTP,DGKE,GPLD1,MAPKAPK2,PRKAG2,UAP1,ACADSB,FAAH,PLPP3,DBI,CTSA,PLD1,ARSB,PTGES,ACOT7 |
| 1.085e-03 | -6.83 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 523 | 74 | 17758 | 1761 |
CRYM,TMX4,MORF4L2,OAT,PJA2,SLC20A1,ERP29,APLP2,ATP6V0B,PSMD1,KIAA1107,EFR3A,REEP1,AKR1B1,ATRNL1,GOT1,TECR,DLG3,BTBD3,ZNF365,TIAM1,GPX4,DOCK4,SEC23A,AKT1,STAU2,HSPA12A,NFE2L1,PRKAR2B,ATP1B1,LDB2,ZFAND5,ABR,OPTN,MAN2A2,SLC25A4,DDOST,KCNK1,GDE1,PLK2,SLC9A6,MADD,SERPINI1,NRGN,PINK1,ENO2,GABRG2,NCKAP1,TRIB2,SLC25A36,B3GALNT1,GNB5,SORL1,AHCY,ATP2B1,SOCS5,PSMB4,UBE2A,FBXO9,PSMA4,RASA1,GNAS,GABRD,SCG2,SPINT2,ITPR1,PPM1H,PGRMC1,MDH1,FHL1,ARHGEF9,TOB1,RUSC1,ACOT7 |
| 1.088e-03 | -6.82 | MULTICELLULAR_ORGANISMAL_DEVELOPMENT | MSigDB lists | MULTICELLULAR_ORGANISMAL_DEVELOPMENT | 1020 | 131 | 17758 | 1761 |
GAA,UGT8,RET,IL18,PLXNA1,DNER,CTGF,SHC3,DPYSL2,FOSB,IL31RA,PAPSS1,KLF3,SGCE,ARHGDIB,ZBTB7B,COL12A1,DPYSL3,MDK,HLF,KCNMB4,DNM1L,HOXA9,LIMK1,BMP1,SERPINI1,TMOD2,NRGN,NR2C2,FGD1,RUNX2,NCKAP1,HPCAL4,ELF3,TFAP4,OSTF1,TNFRSF12A,PIM1,ETV7,MYLIP,ALDH3A2,MDFI,SOCS5,DPYSL5,KLK5,PCDH1,GYLTL1B,NPHP3,RASA1,CDK5R1,ETS2,TIMM8A,COL13A1,ITGA7,CSF1,ALPK3,EGFL7,KLK7,GDF11,DRP2,SHROOM2,APOL2,RARG,MTM1,PAPSS2,NF2,TP53,ERBB2,COL18A1,MRAS,ARTN,LMO4,LHX6,TWIST1,EPHB4,F2R,DVL2,SEMA3B,MBP,UTRN,HTATIP2,ALDH5A1,SHROOM3,NGFRAP1,WFS1,SECTM1,TLE1,EFNA5,MAPK12,GCLM,NKX3-1,PCOLCE,CIT,PBX3,AES,CRABP2,ETS1,GSTP1,HOXB2,FGF19,NRP2,FZD6,HDAC9,FOXP2,CTNNBIP1,ADORA1,PTEN,TFAP2A,BAX,CD9,ARVCF,CITED2,SGCB,SYK,SPRY2,FARP2,HES1,TGIF1,PDGFC,GCLC,STMN3,COL7A1,LEPR,PITX2,ACVRL1,SCG2,ERAP1,HOXB13,SOX8,L1CAM,JARID2 |
| 1.088e-03 | -6.82 | lamellipodium | cellular component | GO:0030027 | 167 | 30 | 17570 | 1756 |
WASF3,ARAP3,RHOA,NF2,SSH1,SYNE2,SPATA13,SCRIB,NCKAP1,ANTXR1,BCAR1,APC2,DAG1,STX3,DPYSL3,KLHL2,PLCG1,PLEKHH2,SWAP70,CDH1,CORO1C,PIK3CA,FGD6,ITGAV,PIEZO1,CTTN,NRBP1,SCYL3,CCDC88A,FGD1 |
| 1.091e-03 | -6.82 | STROIDFINGER | prints domains | PR00047 | 46 | 12 | 4759 | 462 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 1.092e-03 | -6.82 | GNF2_SNRK | MSigDB lists | GNF2_SNRK | 28 | 9 | 17758 | 1761 |
HECA,ARHGEF3,MSL1,JAK1,SEMA4D,STK38,BTN3A2,BTN3A1,RASGRP1 |
| 1.096e-03 | -6.82 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | 843 | 111 | 17758 | 1761 |
PLA2G4A,UNKL,SIGIRR,SLC25A24,ATP8A1,CACNA2D2,FAM101B,CA8,DDR1,KBTBD11,TNFSF9,KCTD9,SH3KBP1,EPDR1,IER3,RNF220,MUC16,ANKS6,CDH1,GRHL1,ZCCHC12,ELF5,STEAP2,AOX1,BCL6,LMAN1,NEB,RASGRP1,GM2A,SMAGP,CYP1B1,MYO5B,DOCK4,LOC81691,CAMSAP3,CD55,SYNE2,PRKCQ,RAB38,ICMT,ITPR3,LDB2,DOCK5,MYL12A,CYP4F3,ARHGEF26,EDNRA,TAPBP,ENPP1,KCNMB4,KLF12,RBM47,LIMK1,STK38,NKD1,RAB11FIP1,MLKL,GLA,TRAF5,SLC25A30,NRGN,COBL,CTHRC1,PCOLCE,ARHGEF3,RASA2,ISYNA1,ANO9,DHRS3,TTYH3,FGF19,SH2D4A,TMEM63A,RASSF8,KIF5B,TAF1B,LYPD3,BDH1,ADAM15,C2orf72,KLF9,CACNA1D,C10orf54,ATP2B1,MYO5A,ABCC1,SOCS5,SNX7,PDGFC,B3GNT2,LCA5,TBC1D8B,NR3C1,IFITM3,PIK3R1,FOS,PCTP,AMDHD1,STEAP1,DGKE,RASGRP2,BCAR3,SLC4A4,RND3,COL13A1,ITGA7,PGRMC1,ARRB1,ARSB,JAK3,TOB1 |
| 1.100e-03 | -6.81 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 835 | 118 | 16036 | 1726 |
CD82,SLC25A13,CUL4B,RET,TP53,ARFGEF1,DNAJB11,ERBB2,OAT,HDAC6,PRKACA,PHLDA1,SH3KBP1,PLS3,CCND1,PSMD1,AP1M2,CDH1,CTGF,SHC3,DOK4,PLCG2,TUBG1,GOT1,CTTN,TECR,PLK1,MAP3K3,DOCK4,SEC61B,AKT1,SH3BGRL,S100A4,ITCH,EZR,ATP1B1,ALCAM,CDK1,ARF4,PRIM1,SOCS3,IRS2,PLCG1,ATP1A1,PTPRJ,JAK1,STK26,DNM1L,LRIG1,NRG1,PIK3C2B,ARF6,GAB1,ARFGEF3,GRN,WASF3,GCLM,COL9A3,TOR4A,LGALS3,CKAP2,UBASH3B,RUSC2,EPS8,PDIA3,CALM3,FBXO6,SEPP1,AIP,HLA-A,H1FX,PPP2R3A,ELF3,SGPL1,TNS3,DOPEY2,IGF1R,ADRBK1,ANKS1B,RANBP1,EXOC8,ERBB3,PIM1,IQGAP3,NCAM1,SLC12A2,SPRY2,SYK,PPP6R1,NUP85,ALDH3A2,ATP2B1,FAH,SOCS5,FADS2,PLSCR1,ADCK3,NR3C1,CALM1,PIK3R1,AK4,YES1,PDK3,FOS,MAPK8IP1,RASA1,FAS,PTPRF,GNAS,ACADSB,ARRB1,PITPNA,MDH1,PLD1,NCAPG2,NDFIP1,PKIA,EHD1 |
| 1.106e-03 | -6.81 | - | gene3d domains | 3.40.720.10 | 31 | 10 | 9988 | 1080 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 1.106e-03 | -6.81 | HOEBEKE_LYMPHOID_STEM_CELL_DN | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_DN | 83 | 18 | 17758 | 1761 |
ALDH6A1,SERPINE2,SLC39A8,RALBP1,ETV5,CTDSPL,TNS1,RAB38,ATP1B1,NFIB,MECOM,PLS3,LIMCH1,HSPB1,TMEM14A,MAFF,S100A6,CKS2 |
| 1.107e-03 | -6.81 | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | 18 | 7 | 17758 | 1761 |
TNS1,HES1,CDH1,SLC20A1,CMTM6,RRBP1,SDC4 |
| 1.107e-03 | -6.81 | MODULE_408 | MSigDB lists | MODULE_408 | 18 | 7 | 17758 | 1761 |
ASAH1,PLD1,NAGA,GM2A,PLCG2,HEXB,GPX4 |
| 1.107e-03 | -6.81 | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP | MSigDB lists | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP | 18 | 7 | 17758 | 1761 |
ARRB1,VSIG10,TACSTD2,NDE1,IGFBP6,SCARA3,SIRPA |
| 1.107e-03 | -6.81 | KANG_CISPLATIN_RESISTANCE_UP | MSigDB lists | KANG_CISPLATIN_RESISTANCE_UP | 18 | 7 | 17758 | 1761 |
GRN,MDK,LZTFL1,FTH1,FAM46A,IGFBP6,MAFF |
| 1.107e-03 | -6.81 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | 191 | 33 | 17758 | 1761 |
SUN1,AVPI1,ARMCX3,PPM1J,CAMKK1,CAST,BLVRB,NDRG2,DDR1,NCS1,RABGGTA,IER3,ITGA3,TSPAN6,PAPSS1,ATRNL1,ECI2,KLF9,CDKN2D,TLE6,RBMS2,SUSD3,FURIN,FNDC3A,MCFD2,ZBTB7B,FRMD4B,AMZ2,CARHSP1,PTPRJ,ARRB1,GEM,SERPINB1 |
| 1.108e-03 | -6.81 | VANTVEER_BREAST_CANCER_ESR1_UP | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_UP | 161 | 29 | 17758 | 1761 |
SUSD3,MAN2B2,LZTFL1,SYBU,HDAC11,C5orf30,COX6C,C3orf18,RBM47,ACADSB,FAAH,SLC16A6,NAT1,IL6ST,KIF13B,LRIG1,FUT8,FAM110C,FAM63A,TMBIM6,FAM102A,TSPAN13,ERBB3,MYLIP,MAST4,CPEB2,PRR15,MCCC2,FARP2 |
| 1.110e-03 | -6.80 | BMI1_DN_MEL18_DN.V1_DN | MSigDB lists | BMI1_DN_MEL18_DN.V1_DN | 139 | 26 | 17758 | 1761 |
COL9A3,TRIM2,S100A4,ESRP1,EPHA4,OGDHL,PDE5A,SEPP1,IDH1,FOS,LEPR,KLHL2,DIRAS3,SCNN1A,CA2,SLC4A4,METTL7A,GNPTAB,ITGA7,SECTM1,SPINT2,SERPINI1,ACOX2,TSPAN1,IFI6,HOXC13 |
| 1.112e-03 | -6.80 | monocarboxylic acid metabolic process | biological process | GO:0032787 | 510 | 74 | 16441 | 1675 |
PLA2G4A,ACACB,UGT8,UGP2,CPT2,MGST2,LPIN3,CYP39A1,CYP26A1,CYP1A1,CYP2S1,ALDH1A3,FABP6,SRR,ACSL4,ACOX2,TECR,EGLN3,CYP1B1,GPX4,PANK1,PRKAR2B,GLO1,IDH1,CYP4F3,POR,ALDH5A1,P4HA2,PEX2,DHTKD1,SLC27A1,ADIPOR1,CYP2U1,LTA4H,SLC27A3,PRKAA2,FAM213B,ENO2,HAL,SLC1A3,CRABP2,DSE,SGPL1,SLC27A6,ECI2,ATP8B1,ABCD1,SYK,NCOA2,MCCC2,MYO5A,CRTAP,ABCC1,CYP26B1,FADS2,PGM1,PRODH,SHMT1,ERO1A,ELOVL3,PPARA,OGDHL,PDK3,RNPEP,AMDHD1,PRDX4,MAPKAPK2,PRKAG2,ACADSB,FAAH,NR4A3,PTGES,ACOT7,EGLN1 |
| 1.112e-03 | -6.80 | PLCG1 events in ERBB2 signaling | REACTOME pathways | R-HSA-1251932 | 37 | 11 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,ERBB2,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 1.114e-03 | -6.80 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | 51 | 13 | 17758 | 1761 |
ORAI2,PLEKHH2,PLSCR1,CSF1,EPHA4,ENPP5,STEAP2,AIF1L,ANO1,NFIB,PARM1,FAS,PCSK5 |
| 1.114e-03 | -6.80 | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | 51 | 13 | 17758 | 1761 |
TXN,SEC61B,IGFBP6,CDKN1C,CD63,NFKBIA,CD70,FTH1,COX6C,GSTP1,S100A2,TP53I3,CAPN1 |
| 1.114e-03 | -6.80 | V$TEF1_Q6 | MSigDB lists | V$TEF1_Q6 | 214 | 36 | 17758 | 1761 |
PRKAA2,AVPI1,FRMD4A,VANGL1,TMPRSS4,PRRG4,EPS8L2,SYTL2,CYP26A1,LMNA,ELF3,CD109,CDKN2C,SCNN1A,ADD3,ST5,CYR61,TINAGL1,WNT3A,ATP1B1,KDM4D,RASGRP2,MDK,PIAS3,PTPRF,MAPKAPK2,PTPRJ,SWAP70,FGFR2,MADD,OVOL1,PRKCDBP,ADIPOR1,ZMIZ1,HOOK1,EHD1 |
| 1.115e-03 | -6.80 | positive regulation of cell differentiation | biological process | GO:0045597 | 796 | 108 | 16441 | 1675 |
FOXO6,NF2,IL15,THRA,INPP5D,RPS6KA1,EPHA4,RET,MORF4L2,CAMK1D,TNFSF9,LTBP3,GRM5,CTGF,NPNT,DACT1,IL6ST,BCL6,DAB2IP,TWIST1,TACSTD2,TMEM64,PACSIN1,TIAM1,RASGRP1,TIMP2,RIPK2,AKT1,LOXL2,SAV1,POR,RHEB,ARHGAP35,SOCS3,DPYSL3,GPRC5B,BHLHB9,PTK7,LIMK1,AXL,TRIOBP,KLF5,EFNA5,NRG1,ITPKA,RGS14,COBL,MAPK12,GRN,BIN1,CTHRC1,RUNX2,LGALS3,SERPINE2,SOX9,ETV5,GDF15,CRABP2,ETS1,TEAD3,NEO1,MECOM,CTNNBIP1,ITGA3,CA2,CYR61,GATA2,MEGF8,BMP7,BAX,SUCO,MAPK11,TNFRSF12A,C10orf54,WNT3A,SYK,TLE6,RIMS2,SOCS5,EPB41L5,TGIF1,HES1,RHOA,MMD,ASPM,RAPGEF2,RGCC,HMG20B,PDE5A,FOS,CD83,GNAS,NCOA3,SEMA4D,ACVRL1,SETD3,TMEM30A,CSF1,AURKA,PPP2R3C,GPER1,ARPC2,MAP3K5,SOX8,ARSB,SEMA3A,L1CAM,EHD1 |
| 1.117e-03 | -6.80 | MODULE_403 | MSigDB lists | MODULE_403 | 45 | 12 | 17758 | 1761 |
TOP2A,CCNE2,PLK1,WEE1,CENPA,CDC20,MYBL2,NEK2,PLK4,CCNB1,CDK1,MELK |
| 1.117e-03 | -6.80 | KINASE_REGULATOR_ACTIVITY | MSigDB lists | KINASE_REGULATOR_ACTIVITY | 45 | 12 | 17758 | 1761 |
CDKN2C,CDKN1C,DNAJC3,MADD,PIK3R1,CDKN1B,PRKAR2B,CDKN2D,MAPK8IP1,CDK5R1,PKIA,SOCS3 |
| 1.117e-03 | -6.80 | ENGELMANN_CANCER_PROGENITORS_UP | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_UP | 45 | 12 | 17758 | 1761 |
CD55,CYP1A1,KCNN4,SLC2A6,ABCG2,LMCD1,CTSZ,ANXA9,GEM,MAST4,MYO5A,B4GALNT1 |
| 1.124e-03 | -6.79 | V$AREB6_01 | MSigDB lists | V$AREB6_01 | 253 | 41 | 17758 | 1761 |
CTHRC1,BMF,LRRFIP2,IGFBP6,GRHL2,TTC39B,CHCHD7,FXYD3,CAMKK1,THRA,GRK6,PDGFB,DDR1,HPCAL4,HDAC9,ITGB8,LLGL2,LYPD3,TSPAN6,SLC16A6,BHLHE41,SLC44A1,TFAP2A,VAT1,CDKN1B,ACSL4,MANF,WNT3A,GAD1,ETV4,SOCS5,CYP26B1,CRB3,TMEM151A,LDB2,FOS,NFIB,MUM1L1,SP6,MAP3K5,OSR1 |
| 1.131e-03 | -6.78 | FERM_2 | prosite domains | PS00661 | 22 | 8 | 11866 | 1235 |
EPB41L5,FRMD4A,NF2,EZR,EPB41L4B,TLN2,EPB41L4A,FRMD4B |
| 1.133e-03 | -6.78 | regulation of neuron death | biological process | GO:1901214 | 239 | 40 | 16441 | 1675 |
CASP3,GCLM,PINK1,TRIM2,CPEB4,NQO1,TP53,BCL2L1,SIX4,KIF14,PIK3CA,BAX,TFAP2A,SORL1,ERBB3,EGLN3,LGMN,F2R,CHP1,SIRT1,KCNIP3,RHOA,AKT1,GCLC,OXR1,CASP9,GRIN1,PPARA,ELK1,CDK5R1,RASA1,OPTN,MDK,BHLHB9,AXL,WFS1,NR4A3,NR4A2,UNC5B,MAP3K5 |
| 1.139e-03 | -6.78 | LIU_SOX4_TARGETS_UP | MSigDB lists | LIU_SOX4_TARGETS_UP | 132 | 25 | 17758 | 1761 |
ENPP4,THRB,LASP1,ILDR1,MBP,ELK3,PRSS23,SOX9,LHFPL2,EPDR1,PDGFA,SWAP70,METTL7A,PLK2,CSF1,ENPP5,FUT8,TMEM143,RYK,SORL1,TLE1,RP2,LGMN,ARL4D,USP43 |
| 1.141e-03 | -6.78 | negative regulation of multi-organism process | biological process | GO:0043901 | 150 | 28 | 16441 | 1675 |
MX1,SIGIRR,TRIM8,PLSCR1,TNIP1,APOBEC3D,IFITM3,NLRX1,ACVR1C,ITCH,MICB,ARHGDIB,APOBEC3H,FBLN1,PRDX4,TFAP4,FAM111A,SP100,TSPAN6,TRAF3IP1,NOD2,TRIM21,HDAC1,ITGAV,IFIT1,OAS3,APOBEC3G,TRIM62 |
| 1.142e-03 | -6.78 | human chr12q23.1 | chromosome location | human chr12q23.1 | 24 | 7 | 26250 | 1887 |
GOLGA2P5,CDK17,ANO4,ANKS1B,DEPDC4,AMDHD1,CCDC38 |
| 1.143e-03 | -6.77 | MODULE_220 | MSigDB lists | MODULE_220 | 325 | 50 | 17758 | 1761 |
UGT8,NKX3-1,EPAS1,EPHA4,SOX9,EPS8,ERBB2,NRG2,CRABP2,GSTP1,EMP2,HOXB2,EFNB1,NEO1,ELF3,ADORA1,CTGF,ARTN,DPYSL2,CALD1,TFAP2A,ARVCF,ALDH3A2,CYP1B1,S100A4,UTRN,MYBL2,ARHGDIB,COL7A1,ROR1,CD40,LDB2,LEPR,DPYSL3,MDK,HLF,SEMA4D,WFS1,CSF1,BMP1,TLE1,EFNA5,SERPINI1,NRG1,FHL1,DRP2,NRGN,SEMA3A,L1CAM,RARG |
| 1.144e-03 | -6.77 | SMID_BREAST_CANCER_LUMINAL_B_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_DN | 524 | 74 | 17758 | 1761 |
PLA2G4A,LTBP1,UGT8,TRIM2,KLK10,PAPSS2,GALNT12,TAP1,NDRG2,IL27RA,MRAS,CYP39A1,NOV,MUC16,CTGF,LMO4,ALDH1A3,ELF5,CDH3,PIK3CD,LAMP3,CYP1B1,CAPN6,SAT1,PTGER4,CR2,KLK6,FZD7,PLCH1,PTK7,HOXA9,KLF5,RRAGD,BIN1,ANXA3,COL9A3,CDKN1C,SERPINE2,CKAP2,ITGA6,CALB2,RAB23,ARL4C,SELL,FBLN1,S100A2,GSTP1,LBR,ADD3,CYR61,CTSC,KCNN4,CALD1,AIM1,GPR161,CYP26B1,KLK5,FBLN5,BTN3A2,RUNX3,LEPR,NFIB,FAS,RASGRP2,GALNT3,BANK1,RND3,ITGA7,DTX4,PGRMC1,KLK7,FHL1,GEM,L1CAM |
| 1.147e-03 | -6.77 | HALLMARK_XENOBIOTIC_METABOLISM | MSigDB lists | HALLMARK_XENOBIOTIC_METABOLISM | 199 | 34 | 17758 | 1761 |
PINK1,PAPSS2,NQO1,BLVRB,NDRG2,FBLN1,CYP26A1,CYP1A1,CA2,CYP2S1,AOX1,TPST1,TMBIM6,AHCY,ACOX2,GAD1,MCCC2,FAH,ALDH2,GCLC,CDA,IDH1,BCAR1,POR,CYB5A,GABARAPL1,FAS,SLC6A6,ETS2,SPINT2,PGRMC1,RAP1GAP,PTGES,XDH |
| 1.149e-03 | -6.77 | mitotic cell cycle process | biological process | GO:1903047 | 720 | 99 | 16441 | 1675 |
CCNE2,SPC25,CEP70,DLGAP5,FOXM1,PSME2,ACTR8,PTTG1,NDC80,TP53,NUF2,PSME1,BCL2L1,CCNB1,PRKACA,STIL,CENPN,FANCI,IER3,CDKN2C,CCND1,WEE1,PSMD1,SETDB2,CNTRL,KIF14,CEP78,DLG1,PLK4,TUBG1,CDKN1B,CDKN2D,PLK1,CENPA,PBK,CDC20,PRKAR2B,NUSAP1,CDCA2,PKMYT1,RAD17,CCNF,ANLN,CDK1,OPTN,PRIM1,PLK2,TRIOBP,KLF11,RGS14,REEP4,PPP2R2D,CKAP2,KLHL13,CIT,EPS8,CDCA8,PSMD10,KIF23,GPSM2,LMNA,SAC3D1,TOP2A,E2F7,SNX18,PTEN,NEK2,BUB1,IQGAP3,SPRY2,NUP85,SUN2,ZWINT,RHOA,KIF20A,PSMB4,ASPM,MYBL2,KIF11,BORA,PSMA4,RASA1,DCTN6,FAM64A,CDCA5,ABCB1,FAM83D,AURKA,CENPE,GEM,CEP41,WDR62,NDE1,NCAPG2,UBE2C,CCNB2,NUP58,ESPL1,MELK |
| 1.152e-03 | -6.77 | TRAF3 (TNF receptor-associated factor 3) | protein interactions | 7187 | 109 | 23 | 16036 | 1726 |
CASP3,TNIP1,RIPK2,IL15,NLRX1,DCAF7,GRIN1,IFIT3,CD40,TNFRSF19,OPTN,FAS,NGFRAP1,TRAF3IP1,OTUB2,GRIN2D,TNFRSF12A,MAP3K5,TRAF5,MYT1,SYK,TMEM173,ABCC1 |
| 1.154e-03 | -6.76 | regulation of leukocyte proliferation | biological process | GO:0070663 | 194 | 34 | 16441 | 1675 |
CASP3,LGALS3,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,GSTP1,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,CSF1,ICOSLG,JAK3,NDFIP1,AHR |
| 1.154e-03 | -6.76 | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MSigDB lists | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 23 | 8 | 17758 | 1761 |
PDGFA,CTHRC1,RAB3B,COL6A2,FXYD3,COL6A1,GEM,FOS |
| 1.154e-03 | -6.76 | EGUCHI_CELL_CYCLE_RB1_TARGETS | MSigDB lists | EGUCHI_CELL_CYCLE_RB1_TARGETS | 23 | 8 | 17758 | 1761 |
CCNE2,KIF20A,NDC80,NEK2,CDCA8,BUB1,CENPE,KIF11 |
| 1.160e-03 | -6.76 | filopodium membrane | cellular component | GO:0031527 | 18 | 7 | 17570 | 1756 |
ITGAV,ITGA3,NF2,ARF6,ANTXR1,SYNE2,UTRN |
| 1.163e-03 | -6.76 | bicellular tight junction | cellular component | GO:0005923 | 110 | 22 | 17570 | 1756 |
DDX58,AMOTL2,FRMD4A,CRB3,BVES,RAPGEF2,TGFBR1,F11R,MPP5,EPCAM,CCND1,TJP3,TBCD,RAP2C,DLG1,CLDN4,POF1B,EPB41L4B,FZD5,DLG3,SHROOM2,OCLN |
| 1.167e-03 | -6.75 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | 184 | 32 | 17758 | 1761 |
DDX58,CAMKK1,HLA-E,ZCCHC24,DNAJB2,HDAC11,SLC20A1,FAM101B,KBTBD11,SUSD2,OTUD1,CDH1,TLN2,RBMS2,FARP2,DDB2,FOXJ2,RAPGEF2,CASP9,ARFRP1,IGSF8,BBS2,DGKE,HS6ST1,RPL12,NR1D2,NR4A3,ARRB1,PER3,CBX7,ARHGEF4,JARID2 |
| 1.167e-03 | -6.75 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 184 | 32 | 17758 | 1761 |
GAA,S100A11,CD63,PSME2,HLA-E,DNAJC3,BTN3A1,AES,NTAN1,HLA-A,RPS6KA2,ITGA3,RALGPS2,CDK16,METTL7A,BHLHE41,DRAM1,RPN2,TAGLN2,SMAGP,FAM69A,ITCH,LITAF,NPC2,BLVRA,FNDC3A,TAPBP,WFS1,NOD2,TLE1,FHL1,MAP3K5 |
| 1.169e-03 | -6.75 | gliogenesis | biological process | GO:0042063 | 172 | 31 | 16441 | 1675 |
EMX1,WASF3,HES1,RHOA,NF2,AKT1,ADGRG1,HDAC11,EPHA4,SOX9,HEXB,ERBB2,SCRIB,MPP5,DNER,NFIB,DAG1,CDK5R1,NFIX,CDKN2C,PTPRJ,PTEN,PLPP3,MATN2,TFAP2A,CD9,DUSP10,DAB2IP,NRG1,ERBB3,SOX8 |
| 1.171e-03 | -6.75 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 169 | 30 | 17758 | 1761 |
CD55,KLHL13,MPP1,TMEM41B,CCDC110,ITGA6,TCF7,EPHA1,SNN,NUCB2,KBTBD11,DDR1,DENND2D,LTBP3,ZNF275,KLHL2,IGF1R,H1F0,IL6ST,DACT1,CDCA7L,NFKBIZ,PIK3CD,CEP41,NDFIP1,ALS2CL,TPCN1,SNPH,KLF7,PCSK5 |
| 1.171e-03 | -6.75 | ESC_V6.5_UP_EARLY.V1_DN | MSigDB lists | ESC_V6.5_UP_EARLY.V1_DN | 169 | 30 | 17758 | 1761 |
ANXA3,PCOLCE,TIMP2,KLK10,S100A4,CCDC34,MRAS,FAM198B,YES1,FBXO6,ALCAM,LTBP3,CMTM7,SOCS3,C16orf74,RASSF8,CTGF,CYR61,CALD1,AXL,ABCA2,TNFRSF12A,CRY2,TINAGL1,SCARA3,FZD5,F2RL1,COL16A1,S100A6,SP5 |
| 1.174e-03 | -6.75 | Signalling to p38 via RIT and RIN | REACTOME pathways | R-HSA-187706 | 232 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 1.174e-03 | -6.75 | ARMS-mediated activation | REACTOME pathways | R-HSA-170984 | 232 | 40 | 8202 | 867 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD10,ERBB2,CALM3,NRG2,PSME1,PDGFB,SPTB,FGF19,CALM2,PDGFA,PSMD1,SHC3,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,IRS2,PPP2R5A,JAK1,FGFR2,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3 |
| 1.176e-03 | -6.75 | LIM_MAMMARY_LUMINAL_MATURE_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_DN | 97 | 20 | 17758 | 1761 |
SORBS1,COL6A2,FRMD4A,TFAP2C,PRICKLE1,KCTD12,SLC1A3,ETS1,MERTK,NFIB,FAS,DAPK2,IRS2,DPYSL2,LMO4,CALD1,COL6A1,TPST1,TINAGL1,COL16A1 |
| 1.176e-03 | -6.75 | KOBAYASHI_EGFR_SIGNALING_24HR_UP | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_UP | 97 | 20 | 17758 | 1761 |
GRN,CPD,BCAM,TRIM2,ALDH6A1,TSC22D3,FXYD3,SYNE2,FTH1,RAB15,SCNN1A,TJP3,CDK19,METTL7A,BCL6,DRAM1,IRF7,LIMCH1,FZD5,CYP1B1 |
| 1.180e-03 | -6.74 | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | MSigDB lists | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 118 | 23 | 17758 | 1761 |
GRN,SPC25,KIF20A,ENO2,DLGAP5,TSC22D3,ARL4C,AK4,KCTD12,GDF15,PHLDA1,DPYSL3,GABARAPL1,DIRAS3,TOP2A,KLF12,FAM64A,WIPI1,SCG2,PLK2,VAT1,MYBL1,CTH |
| 1.188e-03 | -6.74 | NFE2L2.V2 | MSigDB lists | NFE2L2.V2 | 424 | 62 | 17758 | 1761 |
UNKL,GCLM,SLC2A4,REPS2,HJURP,NQO1,MACC1,CAMKK1,GNE,RET,FTH1,AIFM2,EMP2,IL18R1,TSPAN7,SPTB,GRM5,HDAC9,B4GALNT1,RAB15,ANKS6,ITGB8,CYP4F11,REEP1,PAPL,KIAA0319,FUT1,AKR1B1,MDFIC,RTKN2,OSTF1,ALDH7A1,SEMA3G,PANX2,TMEM64,SCARA3,DGKG,ALDH3A2,SYK,OSGIN1,CRTAP,CKAP4,FAM69A,METAP2,PPIF,SHMT1,MFI2,GCLC,STAT4,HTATIP2,ICMT,IDH1,CYP4F3,FZD7,FECH,SLC6A6,IDE,MAP2,ACVRL1,ZNF367,GLA,L1CAM |
| 1.192e-03 | -6.73 | FoxO signaling pathway | KEGG pathways | hsa04068 | 134 | 27 | 6908 | 758 |
SIRT1,PRKAA2,PLK1,FOXO6,SLC2A4,AKT1,PIK3R1,TGFBR1,CCNB1,GABARAPL1,CCND1,IRS2,PRKAG2,IGF1R,PTEN,PLK2,SGK3,PLK4,BCL6,PIK3CA,CDKN1B,SGK1,MAPK11,PIK3CD,CCNB2,CDKN2D,MAPK12 |
| 1.198e-03 | -6.73 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 381 | 58 | 16441 | 1675 |
GCLM,PINK1,NKX3-1,BMF,LGALS3,ITGA6,RET,TP53,PDIA3,PSMD10,TGFBR1,BCL2L1,GSTP1,ERP29,BCAP31,LMNA,IER3,TFAP4,DAPK2,SP100,CTSC,PTEN,SIVA1,DAPK1,BAX,PLEKHF1,TMBIM6,DAB2IP,BUB1,TNFRSF12A,CTTN,FAIM,CDKN2D,CTH,SIRT1,PPIF,AKT1,FIGNL1,PLAUR,GCLC,STRADB,PELI3,PRKRA,SLC25A5,MAPK8IP1,G2E3,FAS,DNM1L,SCG2,WFS1,MADD,NR4A2,NRG1,ITGAV,GPER1,UNC5B,HSPB1,IFI6 |
| 1.199e-03 | -6.73 | regulation of mononuclear cell proliferation | biological process | GO:0032944 | 187 | 33 | 16441 | 1675 |
CASP3,LGALS3,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,CSF1,ICOSLG,JAK3,NDFIP1,AHR |
| 1.202e-03 | -6.72 | V$FOXO4_02 | MSigDB lists | V$FOXO4_02 | 246 | 40 | 17758 | 1761 |
CDKN1C,CHCHD7,THRA,ETV5,ARFGEF1,TEX2,RAB6A,PHLPP1,SEPP1,KREMEN1,ZFYVE9,TFAP4,FOXP2,FRY,ITGB8,IL6ST,FAM63A,DIXDC1,CITED2,TIAM1,SCN3A,DOCK4,TGIF1,TRIM8,KIF20A,NR3C1,NUB1,LRRC1,NFIX,GNAS,XKRX,PITX2,KLF12,VSIG10,NR4A2,NRG1,KLF5,LEMD1,MAFF,EHD1 |
| 1.206e-03 | -6.72 | positive regulation of Ras protein signal transduction | biological process | GO:0046579 | 33 | 10 | 16441 | 1675 |
RASGRF1,ADGRG1,CSF1,ARRB1,ERBB2,NRG1,RASGEF1A,F2R,F2RL1,RASGRP1 |
| 1.210e-03 | -6.72 | skin-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-squamous_cell_carcinoma | 14911 | 1518 | 17775 | 1757 |
HECA,AK7,SLC25A13,RET,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,RIMS3,ATP5H,MEGF8,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,MCCC2,PAQR7,HPS3,NPHP3,PCTP,SFXN5,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,TMEM200B,MX1,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,FUT2,ITGB8,IGSF9,MGAT4A,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,NUB1,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,ABCA2,NTN4,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,KDM4D,TRIM9,PLEKHG6,HS6ST1,KCNMB4,AGPAT2,KLF12,ARRDC1,KLF11,RRAGD,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,RASA2,PDCL,ADCK5,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,SYTL2,IER3,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,PARM1,NRP2,FZD6,SH2D4A,M6PR,ZDHHC21,CD109,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,ALDH7A1,SYK,ATP2B1,GCNT1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,TACSTD2,MARCH2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,SCOC,TBC1D1,TSPAN7,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,SOCS5,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,ATP8B3,ANTXR1,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,BCL2L1,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,CCDC149,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,DEPDC1,IGFBP6,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,FUT8,DRAM1,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,CENPA,ITCH,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,ETV7,GAD1,SLC12A2,CCDC88A,SNX7,MDFI,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,C3orf58,STEAP1,MFSD7,RANBP9,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,JAK3,COL16A1,RARG,AFAP1,APOL2,SNX30,CCNE2,LMO7,NCKAP5,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,DIXDC1,EPB41L4B,ECE1,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,ARHGEF11,TSPAN15,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,ANKRD6,LIMK1,AGFG2,SERPINB6,RELL1,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,SPTLC2,DCP2,CYB5A,DHX32,PTPRF,NCOA3,SCARB2,SEMA4D,SETD3,ITPR1,AURKA,FBXO27,DRP2,NDE1,ZNF502,SERPINB1,XDH,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,TESK2,PKP2,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ETS1,SRPX2,HOXB2,TIPRL,PDIA4,NEO1,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,WWP1,NPTXR,TPCN1,AMOTL2,LCA5,FMN1,FAM160A1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,PDGFB,SDC1,SHC3,MKRN3,DUSP10,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,KLK6,ANLN,PRKRA,IDH1,LHFPL2,ZBTB7B,OPTN,DPYSL3,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,LTBP2,ATP1B3,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,ABRACL,EFR3A,N4BP3,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,DSE,CRABP2,SLC9A2,PPP2R3A,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,PPFIBP2,TAP1,PLXNA1,CCNB1,FAM101B,SLC20A1,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,SMYD5,XKR8,ORAI2,TMEM68,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,CCNF,SAV1,TP53I3,SPNS3,ARHGEF26,AHRR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,TMEM54,ISM1,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PLA2G4A,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,RNF182,AIFM2,MNS1,TMPRSS4,APLP2,FAM46A,CDKN1B,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,PRKCQ,SLC11A2,C15orf39,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,JAK1,PPP2R5A,SLC27A1,NRG1,KLF5,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,EDNRA,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,LRIF1,ALS2CL,OXR1,GYLTL1B,BTN3A2,AMDHD1,MUM1L1,GLCE,GNAS,XKRX,FECH,BCAR3,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,FAM92A1,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,GOT1,RPN2,TWIST1,F2R,PDIA6,SCYL3,FRS3,SUSD3,MAP3K3,SLC39A8,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SUN2,SYPL1,RAB3B,NR4A1,GCLC,DEPDC4,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,DHRS2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 1.212e-03 | -6.72 | bone-other-chondroma | COSMIC cancer mutations | bone-other-chondroma | 6 | 4 | 17775 | 1757 |
GNAS,ERBB2,IDH1,TP53 |
| 1.212e-03 | -6.72 | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | 6 | 4 | 17775 | 1757 |
CDKN2C,IDH1,PTEN,TP53 |
| 1.212e-03 | -6.72 | TSH | COSMIC cancer mutations | TSH | 6 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 1.212e-03 | -6.72 | pituitary-adenoma-TSH | COSMIC cancer mutations | pituitary-adenoma-TSH | 6 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 1.213e-03 | -6.72 | GSE17721_LPS_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_2H_BMDM_UP | 192 | 33 | 17758 | 1761 |
ARHGEF3,TM2D2,ENO2,TSPAN15,SDC4,KCTD12,MPP5,TEX2,CD274,CYP39A1,TOP2A,HSF2,ZFP36,IL6ST,ALDH7A1,EGLN3,MYLIP,MAP3K3,MX1,SIRT1,PDGFC,SLC37A1,IFIT3,FOS,NIN,ETS2,SCG2,RND3,KBTBD2,DCK,SH3BGRL2,SLC27A1,IFIH1 |
| 1.213e-03 | -6.72 | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | 192 | 33 | 17758 | 1761 |
RMND5A,CMAS,CDKN1C,HLA-E,SDC4,KIF23,NDRG2,BCL2L1,OAT,MNS1,PLS3,BTG3,ADRBK1,MKRN3,KLF3,FAM63A,PIK3CD,MPHOSPH9,MDFI,CLCN3,SEC23A,ASPM,MPP1,GLO1,FAS,ANKRD10,NR1D2,ITPR1,SLC27A1,GRIN2D,ITGAV,TRAF5,RRAGD |
| 1.215e-03 | -6.71 | QI_PLASMACYTOMA_UP | MSigDB lists | QI_PLASMACYTOMA_UP | 254 | 41 | 17758 | 1761 |
CASP3,LASP1,NFKBIE,RPS6KA1,UBASH3B,CD82,ITGA6,IL18,IL27RA,PDGFB,IL17RB,SP100,SH3BP1,TMBIM6,TRIM21,IRF2,RP2,SNX10,S100A13,ARAP2,HPS3,PLSCR1,PLEKHO1,SLC11A2,ARHGDIB,CD40,STK17B,CASP4,FRMD4B,FAS,SWAP70,TJP3,AXL,LIMK1,NFKBIA,ARRB1,STK39,ICOSLG,PTGES,CAPN1,EHD1 |
| 1.216e-03 | -6.71 | regulation of cell division | biological process | GO:0051302 | 294 | 47 | 16441 | 1675 |
NKX3-1,DLGAP5,MACC1,CIT,PTTG1,CALM3,KIF23,PSMD10,PDGFB,STIL,CALM2,SUSD2,CCND1,PDGFA,E2F7,RPS6KA2,IGF1R,PTEN,BMP7,KIF14,NEK2,BUB1,PIM1,ZBTB18,PLK1,PDGFC,RHOA,AKT1,ASPM,CALM1,CDC20,RGCC,NUSAP1,PKMYT1,ANLN,BORA,KIF11,PGF,MDK,NCOA3,FGFR2,CDCA5,AURKA,CENPE,UBE2C,E2F8,ESPL1 |
| 1.223e-03 | -6.71 | RHO GTPases activate IQGAPs | REACTOME pathways | R-HSA-5626467 | 13 | 6 | 8202 | 867 |
CALM2,CALM3,IQGAP3,CDH1,IQGAP1,CALM1 |
| 1.223e-03 | -6.71 | CLEC7A (Dectin-1) induces NFAT activation | REACTOME pathways | R-HSA-5607763 | 13 | 6 | 8202 | 867 |
CALM2,CALM3,ITPR2,ITPR3,ITPR1,CALM1 |
| 1.227e-03 | -6.70 | Kinesin_assoc | interpro domains | IPR032405 | 6 | 4 | 18293 | 1814 |
KIF1C,KIF13A,KIF14,KIF13B |
| 1.228e-03 | -6.70 | CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | CARBOHYDRATE_METABOLIC_PROCESS | 177 | 31 | 17758 | 1761 |
B3GALT6,GFPT1,GAA,SLC2A4,ALDH2,UGP2,GNPDA1,COG2,GUSB,GNE,XYLT1,ACO1,GALNT7,PDK3,IDH1,GLCE,B4GALNT1,IRS2,GNS,HS6ST1,FUT2,HPSE,UAP1,PTEN,FUT8,FUT1,AKR1B1,HS3ST3B1,GLA,PHKA2,GAD1 |
| 1.230e-03 | -6.70 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 408 | 60 | 17758 | 1761 |
AVPI1,ARMCX3,PPP1R2,AASS,HLA-E,TSC22D3,SLC25A13,PDGFB,APC2,PHLDA1,TNFSF9,H1FX,BTG3,SCNN1A,RPS6KA2,FAM46A,CYR61,BHLHE41,COL6A1,FOSB,IFIT1,ARMCX6,F2R,GAD1,MYLIP,SCYL3,CTH,CLCN3,HES1,ELK3,PLSCR1,IFITM3,RAPGEF2,CASP9,C3orf52,NFE2L1,EZR,YES1,STK17B,BSDC1,ARF4,GABARAPL1,STK17A,GNAS,GALNT3,IRS2,SLCO4A1,JAK1,PDLIM3,NFKBIA,NR4A3,ZNF165,IRF7,ATP1B3,GLA,GEM,ARF6,MAFF,JARID2,ABCG1 |
| 1.230e-03 | -6.70 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 408 | 60 | 17758 | 1761 |
FOXO6,BMF,ARMCX3,NUAK1,UBASH3B,ARL4C,SLC1A3,FBLN1,TTYH3,BMP2K,NRP2,PARM1,SH3KBP1,LMNA,IRF2BPL,SIPA1L2,FAM46A,PTEN,PAPSS1,DAB2IP,DIXDC1,C10orf54,LGMN,ARMCX6,EGLN3,C9orf72,ATP2B1,IGDCC4,CHSY3,REC8,DOCK4,CD55,RAB3B,DUSP4,LDB2,C15orf39,ANTXR1,CD83,NFIX,EDNRA,AHRR,CACHD1,ENPP1,KLF12,RND3,ANKRD6,COL13A1,P4HA2,TSPAN18,MATN2,ZNF704,RHOBTB2,NR4A2,KLF11,CENPE,SYT13,AHR,ISOC1,DEF6,KLF7 |
| 1.230e-03 | -6.70 | MODULE_60 | MSigDB lists | MODULE_60 | 408 | 60 | 17758 | 1761 |
GRN,MYL9,GAA,BCAM,PCOLCE,IGFBP6,HSPG2,EPAS1,S100A11,CRYM,THRA,BLVRB,TAP1,TP53I11,ITPR2,PKN1,DHRS3,TSPAN7,SPTB,CARD10,ARHGEF16,CHPF,M6PR,IER3,CCND1,TYMP,ST5,TRANK1,LLGL2,RGS3,BDH1,COL6A1,GOT1,IGFBP2,ECE1,NOTCH3,LGMN,CITED2,SMAGP,COL6A2,NR4A1,S100A4,CDA,TCF7,ARFRP1,PKMYT1,ICMT,CDK5R1,TIMP3,AGPAT2,PVRL2,DHRS2,ITGA7,WFS1,SLC4A3,PIK3C2B,CDK18,TMEM159,JAK3,ABCA1 |
| 1.234e-03 | -6.70 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | 34 | 10 | 17775 | 1757 |
GNAS,AKT1,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 1.236e-03 | -6.70 | regulation of protein catabolic process | biological process | GO:0042176 | 430 | 64 | 16441 | 1675 |
DLGAP5,PSME2,CUL4B,PSME1,CCNB1,PRKACA,BARD1,APC2,BCAP31,RAD23A,IER3,PSMD1,DACT1,CDKN1B,DAB2IP,TIPARP,PLK1,TIMP2,ERLEC1,AKT1,ITCH,PBK,USP18,CDC20,EZR,RNF19B,SNX12,CDK1,PLK2,NKD1,NRG1,PINK1,GGA1,DNAJB2,SOX9,ASB9,PSMD10,TRIB2,PPP2R3A,RNF128,PTEN,CTSC,CST3,UBE2J1,SORL1,BUB1,MYLIP,SOCS5,PSMB4,GCLC,NUB1,FURIN,PRICKLE1,PSMA4,GPLD1,TIMP3,FAM83D,AURKA,YOD1,CENPE,UBE2C,NDFIP1,ESPL1,USP43 |
| 1.236e-03 | -6.70 | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | 1176 | 148 | 17758 | 1761 |
CCNI,TXN,ADD1,TSC22D3,CAMK1D,SLC20A1,CMTM6,FANCI,ZNF275,WEE1,CYP1A1,LRRC6,CTGF,CABP1,FOSB,AOX1,DUSP10,TUBG1,PIK3CD,TIPARP,CCDC38,ORAI2,TRIM8,CENPA,ITCH,ARHGDIB,F12,ZFAND5,IDH1,SESN1,RHEB,LRRC42,TMEM164,PLEKHG6,RBM47,MADD,CAB39,EIF4EBP2,SP6,ARF6,WBSCR27,NXT2,RMND5A,CDK17,KIF23,DHRS3,TNFRSF19,PRRG4,PAIP2B,ZNRF2,KCNN4,SLC16A6,ATP5H,FAM13B,RUNDC3B,OSTF1,C10orf54,PIKFYVE,ALDH3A2,FAM69A,PAQR7,GFPT1,DDB2,MRPS33,ADCK3,VEZT,AMDHD1,GLT8D2,NCOA3,DCK,TMEM30A,FGD6,MDH1,NIPA1,EGLN1,ARHGAP11A,TPRN,LZTFL1,SLC25A24,AVPI1,NF2,PTTG1,TP53,TESK2,FTH1,NUF2,GRK6,CD274,MNS1,SYTL2,APLP2,WDR44,CDKN1B,ACSL4,ARL4D,CDKN2D,SEPHS1,SIRT1,CPD,ERLEC1,MBP,SEPT6,SERTAD3,IGSF8,GTF2A2,KCTD2,SNX12,ATP10D,FZD7,AMZ2,PTPRJ,PPP2R5A,RBL1,ABHD12,CDK19,ANXA9,RGS14,C1orf43,DAP,FAM134A,ARL4C,ERI2,ETS1,LBR,AKIRIN1,KIF5B,RNF128,FAM63A,PLEKHF1,CNOT6L,CITED2,ACBD5,HMMR,SYPL1,OPLAH,ZWINT,RHOA,LRRC66,YES1,KIF11,NMI,ERAP1,FAM117A,ETAA1,ITGAV,ARSB,NDFIP1,JARID2 |
| 1.237e-03 | -6.70 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 140 | 26 | 17758 | 1761 |
TRIP10,TESK1,ATP8A1,ETV5,AK4,SPR,KBTBD11,MERTK,CD83,PDIA4,NEO1,PRIM1,EPCAM,SLC25A4,NFKBIA,TRAF3IP1,ALDH1A3,MAP3K9,NR4A3,FZD5,NPTXR,F2RL1,IFI6,RASGRP1,OCLN,MED22 |
| 1.245e-03 | -6.69 | ARMCX5 (armadillo repeat containing, X-linked 5) | protein interactions | 64860 | 3 | 3 | 16036 | 1726 |
APPBP2,DCP2,TP53 |
| 1.245e-03 | -6.69 | TMEM245 (transmembrane protein 245) | protein interactions | 23731 | 3 | 3 | 16036 | 1726 |
FBXO6,LYPD3,LYPD6 |
| 1.247e-03 | -6.69 | CD7 (CD7 molecule) | protein interactions | 924 | 9 | 5 | 16036 | 1726 |
CTSL,CPTP,NFKBIA,SECTM1,PIK3R1 |
| 1.247e-03 | -6.69 | ZMIZ1 (zinc finger, MIZ-type containing 1) | protein interactions | 57178 | 9 | 5 | 16036 | 1726 |
PIAS3,CACHD1,CNTNAP2,TBC1D4,TP53 |
| 1.259e-03 | -6.68 | PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha)) | protein interactions | 5295 | 192 | 35 | 16036 | 1726 |
WASF3,INPP5D,RET,ERBB2,TGFBR1,TEC,SH3KBP1,SLC9A2,IGF1R,PIK3AP1,IL6ST,PIK3CA,TUBG1,DAB2IP,PIK3CD,ERBB3,SYK,NUP85,SIRT1,ADAMTS2,AKT1,TNIP1,PIK3R1,EZR,CD40,BCAR1,RASA1,IRS2,JAK1,FGFR2,AXL,NFKBIA,MAP3K5,JAK3,GAB1 |
| 1.263e-03 | -6.67 | NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS | 663 | 90 | 17758 | 1761 |
CASP3,SIGIRR,NF2,S100A11,CNOT8,TP53,COL18A1,FTH1,BCL2L1,TP53I11,BARD1,IER3,CDKN2C,BTG3,FABP6,FOSB,DLG1,BCL6,CDKN1B,IRF2,TWIST1,CDKN2D,APOBEC3G,SIRT1,ING1,TNIP1,DRAP1,SERTAD3,CDA,HTATIP2,ARHGDIB,GLO1,RAD17,PRKRA,SESN1,CDK1,ARHGAP35,SOCS3,MID1IP1,KLF12,HDAC1,TLE1,NRG1,IRF7,KLF11,GLA,ARF6,HSPB1,MAPK12,GLIS3,RUNX2,ARAP3,NFKBIE,CDKN1C,IGFBP6,NKRF,GSTP1,ETS1,HDAC9,CARD8,IGF1R,PTEN,PAIP2B,BMP7,BAX,ATP8B1,WWP1,PIM1,OSGIN1,MDFI,SOCS5,TGIF1,ELK3,GCLC,FURIN,RUNX3,EIF2AK1,NPHP3,RASA1,FAS,CDK5RAP1,SCG2,SEMA4D,ACVRL1,DHRS2,CGREF1,IFI6,TOB1,HIPK3,CD33 |
| 1.264e-03 | -6.67 | V$CEBPA_01 | MSigDB lists | V$CEBPA_01 | 231 | 38 | 17758 | 1761 |
PLA2G4A,SPRED1,NCKAP5,HOXB7,THRA,CA8,S100A2,PDGFB,NRP2,SIRPA,SCML1,CD109,FOXP2,ANKS1B,LMO4,LHX6,MITF,RRBP1,BCL6,CLDN4,PDE4D,SSH3,SMARCA2,CD55,MCTP1,TRIM8,MOSPD2,LONRF3,SERTAD4,RC3H2,CBX6,PPP1R14C,SPTLC2,COL13A1,RHOBTB2,ARF6,TOB1,JARID2 |
| 1.265e-03 | -6.67 | PID_HIF2PATHWAY | MSigDB lists | PID_HIF2PATHWAY | 34 | 10 | 17758 | 1761 |
SIRT1,EPAS1,ABCG2,TWIST1,SLC11A2,ELK1,CITED2,EGLN3,ETS1,EGLN1 |
| 1.265e-03 | -6.67 | SIG_CD40PATHWAYMAP | MSigDB lists | SIG_CD40PATHWAYMAP | 34 | 10 | 17758 | 1761 |
NFKBIE,NFKBIA,PIK3R1,PIK3CA,MAPK11,PIK3CD,CD40,TRAF5,MAPK8IP1,MAPK12 |
| 1.267e-03 | -6.67 | protein serine/threonine kinase activator activity | molecular function | GO:0043539 | 18 | 7 | 16491 | 1673 |
CALM3,CAB39,CALM2,SPRY2,IQGAP1,CDK5R1,CALM1 |
| 1.270e-03 | -6.67 | Prostate cancer | KEGG pathways | hsa05215 | 89 | 20 | 6908 | 758 |
CCNE2,PDGFC,NKX3-1,AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,PDGFB,GSTP1,PDGFA,CCND1,IGF1R,PTEN,FGFR2,NFKBIA,PIK3CA,CDKN1B,PIK3CD |
| 1.270e-03 | -6.67 | Prostate cancer | KEGG pathways | ko05215 | 89 | 20 | 6908 | 758 |
CCNE2,PDGFC,NKX3-1,AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,PDGFB,GSTP1,PDGFA,CCND1,IGF1R,PTEN,FGFR2,NFKBIA,PIK3CA,CDKN1B,PIK3CD |
| 1.273e-03 | -6.67 | Sema4D in semaphorin signaling | REACTOME pathways | R-HSA-400685 | 27 | 9 | 8202 | 867 |
MYL9,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,ARHGAP35 |
| 1.274e-03 | -6.67 | establishment of organelle localization | biological process | GO:0051656 | 342 | 53 | 16441 | 1675 |
GRN,DLGAP5,CDCA8,NDC80,CTSZ,GPSM2,SYTL4,CCNB1,SYTL2,KIF5B,AP1M2,CTSC,LLGL2,KIF14,DPYSL2,DLG1,LMAN1,RAB27B,PACSIN1,SYTL3,SPRY2,PPP6R1,MYO5A,RASGRP1,SUN2,SEC23A,CENPA,RAB3B,SYNE2,EZR,SCRIB,KIF13A,COL7A1,NUSAP1,MCFD2,BBS2,STX3,TRIM9,AP1AR,SERPINA1,FGFR2,PVRL2,SYT7,WIPI1,CDCA5,FAM83D,SYT13,CENPE,GEM,NDE1,SHROOM2,ESPL1,SNPH |
| 1.280e-03 | -6.66 | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 185 | 32 | 17758 | 1761 |
CDK17,ARAP3,NFKBIE,CUL4B,TMX4,HERC5,F11R,SAMD9,DSE,SIRPA,SP100,SNX18,FRYL,PHTF1,ECE1,CNOT6L,CNPY3,SNX10,XKR8,MX1,TACC1,LPGAT1,SERTAD3,ATP10D,CRISPLD2,MAPKAPK2,STK38,SIPA1L1,CAB39,SERPINB1,PTGES,DEF6 |
| 1.280e-03 | -6.66 | GSE3982_MAC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_UP | 185 | 32 | 17758 | 1761 |
PLA2G4A,PRKAA2,ARHGEF3,CKAP2,CPT2,PTTG1,C6orf106,GTF3A,SLC20A1,PPP2R3A,SGPL1,TOP2A,DOPEY2,PSMD1,PAPSS1,GTF2F2,RPN2,TACSTD2,DIXDC1,MCCC2,FAH,SOCS5,NFE2L3,GNA11,FUCA1,DDOST,P4HA2,CSF1,SPINT2,PEX2,ERAP1,OTUB2 |
| 1.280e-03 | -6.66 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | 185 | 32 | 17758 | 1761 |
BIN1,SLC35D2,CDK17,ATP9A,CAST,DHX8,IL27RA,SBF1,BMP2K,GNS,LRRC45,ADD3,CA2,WDR44,IFIT1,KLF9,RCAN3,TPCN1,OSGIN1,SULF2,DDB2,TBC1D8B,OSTM1,OXR1,TTC7A,ABR,RAB11FIP2,KBTBD2,ABCB1,ATP1B3,NRBP1,ESYT2 |
| 1.287e-03 | -6.66 | CATTGTYY_V$SOX9_B1 | MSigDB lists | CATTGTYY_V$SOX9_B1 | 343 | 52 | 17758 | 1761 |
BMF,TRIM2,HSPG2,KLHL13,ARFGEF1,NDRG2,HMGN3,BCL2L1,MGAT5B,TRIB2,VASH1,ETS1,PSIP1,SYTL2,HDAC9,CCDC92,FOXP2,WEE1,CALD1,LHX6,RANBP1,MITF,ADAM15,DAB2IP,NOTCH3,TIAM1,SEPHS1,MDFI,DPYSL5,DOCK4,SUN2,ATL1,TGIF1,MBP,MOSPD2,SLC39A8,ITCH,PANK1,RGAG1,KIF1C,PRKCQ,ZFAND5,PDIK1L,RANBP9,MAPK8IP1,ARF4,ARHGEF19,FAT4,TLE1,EIF4EBP2,SPTBN5,NDST3 |
| 1.288e-03 | -6.65 | antigen processing and presentation of peptide antigen via MHC class I | biological process | GO:0002474 | 102 | 21 | 16441 | 1675 |
SEC23A,SEC61B,PSMB4,HLA-E,PSME2,HLA-F,UBE2A,TAP1,PDIA3,PSMD10,PSME1,PSMA4,BCAP31,HLA-A,HLA-B,TAPBP,PSMD1,ERAP1,ITGAV,HLA-C,ERAP2 |
| 1.293e-03 | -6.65 | positive regulation of MAPK cascade | biological process | GO:0043410 | 596 | 84 | 16441 | 1675 |
SPRED1,AVPI1,PSME2,EPHA4,NRG2,ERBB2,PSME1,NENF,PDGFB,ERP29,SPTB,GRM5,CALM2,PDGFA,ST5,PSMD1,CTGF,NPNT,SHC3,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,MAP3K3,TIMP2,RIPK2,FZD4,CD40,CDK1,MAP3K6,FZD7,IRS2,PLCG1,JAK1,ANKRD6,MADD,NOD2,PRKCDBP,SPTBN5,NRG1,F2RL1,GAB1,RASA2,CALM3,PSMD10,TGFBR1,PKN1,FGF19,IGF1R,ADORA1,PTEN,MAP3K9,MDFIC,MAPK11,MYDGF,ERBB3,IQGAP3,NCAM1,SYK,SPRY2,MDFI,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,PDE5A,PSMA4,RASA1,FAS,MAPKAPK2,BANK1,FGFR2,PELI2,RYK,ARRB1,GRIN2D,GPER1,FZD5,MAP3K5,JAK3,XDH |
| 1.305e-03 | -6.64 | Rab GTPase binding | molecular function | GO:0017137 | 89 | 19 | 16491 | 1673 |
MYO5B,EXPH5,PIFO,RUSC2,SYTL4,SYTL2,OPTN,RABGGTA,ACAP2,MLPH,LLGL2,RAB11FIP2,RAB11FIP1,MYRIP,SYTL3,C9orf72,RIMS2,MYO5A,EHD1 |
| 1.306e-03 | -6.64 | Rap1 signaling pathway | KEGG pathways | ko04015 | 211 | 38 | 6908 | 758 |
ARAP3,CALM3,MRAS,PDGFB,FGF19,CALM2,PDGFA,SIPA1L2,IGF1R,CDH1,PIK3CA,MAPK11,PIK3CD,TLN2,F2R,PLCB2,TIAM1,FARP2,DOCK4,PDGFC,RHOA,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,RASGRP2,GNAS,PGF,PLCG1,FGFR2,CSF1,SIPA1L1,EFNA5,RGS14,RAP1GAP,MAPK12 |
| 1.306e-03 | -6.64 | Rap1 signaling pathway | KEGG pathways | hsa04015 | 211 | 38 | 6908 | 758 |
ARAP3,CALM3,MRAS,PDGFB,FGF19,CALM2,PDGFA,SIPA1L2,IGF1R,CDH1,PIK3CA,MAPK11,PIK3CD,TLN2,F2R,PLCB2,TIAM1,FARP2,DOCK4,PDGFC,RHOA,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,RASGRP2,GNAS,PGF,PLCG1,FGFR2,CSF1,SIPA1L1,EFNA5,RGS14,RAP1GAP,MAPK12 |
| 1.310e-03 | -6.64 | lower_third | COSMIC cancer mutations | lower_third | 8323 | 883 | 17775 | 1757 |
ACACB,AASS,SLC25A13,HEXB,RET,CACNA2D2,DHX8,FAM102B,CA8,BARD1,LTBP3,GRM5,EPDR1,DAPK2,PSMD1,MUC4,ALDH1A3,KLF3,CLDN4,SEMA3G,RNF26,TIAM1,TIPARP,MGAT5,ERAP2,NWD1,SMARCA2,TNIP1,SH3BGRL,CDA,MTRF1L,TMEM151A,PRKAR2B,LOXL2,PPP1R14C,RNF19B,COL12A1,PIAS3,ENPP1,DNM1L,ATP7B,FAM114A1,NOD2,AGFG2,ITPKA,ARF6,NXT2,SCN5A,NFKBIE,FAM169A,ITGA6,SOX9,SLC36A4,MERTK,TTYH3,MARCH8,GNS,FRY,MEGF8,RIMS3,FLRT3,FAM13B,PCYOX1,CADPS2,ALPK1,PANX2,ZMYM1,NCAM1,MYLIP,DGKG,NUP85,HPS3,SLC37A1,KIF20A,SALL4,STAT4,NPHP3,PCTP,DCP2,STK17A,DHX32,PTPRF,CACHD1,NCOA3,SLC4A4,ETS2,SETD3,ITPR1,CLMN,AURKA,GDF11,TMEM159,NDE1,DRP2,ARPC2,SERPINB1,ZNF502,TMEM173,RUSC1,XDH,ADAMTS16,EGLN1,DOCK9,NQO1,ACTR8,RGS20,TESK2,PKP2,PRSS22,NUF2,GRK6,PRKACA,APC2,TNFSF9,ZNF385B,RCN1,CCND1,MUC16,RNF220,ST5,SP100,DACT1,XYLT2,ENPP5,ACSL4,RASGEF1A,ZNF365,MYT1,SCN3A,TMEM200B,ENPP4,CAMSAP3,SSH3,COL6A2,C6orf1,RIPK2,SEPT6,PLEKHO1,SYNE2,SAT1,CDCA2,NUSAP1,SHROOM3,CORO1C,SLC9A6,AXL,INPP4B,PLEKHG1,PNPLA6,RGS14,SLC25A30,ISOC1,TTC8,NKX3-1,TNRC6C,CKAP2,OSGIN2,PDIA3,ANO9,PKN1,ETS1,PDIA4,DTX3L,ADD3,FUT2,IGSF9,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,BAX,ADAM15,TMBIM6,ECI2,WWP1,SGCB,TPCN1,MED22,PARP9,PVRL4,ADAMTS2,LCA5,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,EIF5A2,MRS2,NUB1,GRIN1,CXorf57,AK4,SNTB1,CRISPLD2,GALNT3,RPL12,RAB11FIP2,ACVRL1,SYT7,PPM1H,CENPE,ITGAV,ACOT7,TLL2,TMEM131,BCAM,KIAA1462,TRIM2,EPAS1,GNPDA1,EPHA4,CUL4B,ARFGEF1,NDC80,LMCD1,DNAJB11,TEX2,ITPR2,PDGFB,SPTB,FANCI,PLS3,SUSD2,CPNE2,RPS6KA2,MKRN3,IL6ST,PAPSS1,SLC44A1,ABCA2,DUSP10,ANO4,TLN2,MYBL1,TRAM1,DDX59,NEB,SMAGP,ZNF462,PLK1,THRB,PCGF5,CELSR2,STAU2,CBX6,EZR,CR2,IDH1,SESN1,ZBTB7B,DZIP1L,DPYSL3,OPTN,KDM4D,TRIM9,PLEKHG6,MFAP3L,HS6ST1,MSL1,KLF12,MAP2,P4HA2,ZNF367,RAB11FIP1,ARRDC1,PIK3C2B,PIEZO1,GLCCI1,MYL12B,RRAGD,PRKAA2,PARP12,RUNX2,UBASH3B,RASA2,FXYD3,PDCL,ADCK5,CNTNAP2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,DAZAP1,IGF1R,SPIN4,FRAS1,KIF13B,EXOC8,PIM1,FAR2,PLCB2,ABCC1,CHSY3,DPYSL5,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,SPATA13,STRADB,SCRIB,EIF2AK1,G2E3,PRX,FOXD2,COQ10A,PVRL2,COL13A1,KBTBD2,PHLPP2,ITGA7,CSF1,MFSD2A,PRPS2,SLC2A6,LTBP2,ZDBF2,PLD1,SEMA3A,CCNB2,RNF146,USP43,HOXB7,UGP2,XYLT1,TP53,CCDC68,ERBB2,SLC7A2,STIL,SYTL2,TTC21B,WDR44,EFR3A,LMO4,N4BP3,PLCG2,SRR,BCL6,PLK4,GLB1L2,ESPN,NOTCH3,OAS3,SCN2A,GM2A,CTH,CPD,SIRT1,CLCN3,TMTC1,ERLEC1,AKT1,S100A4,CDC20,PTGER4,ATP13A2,DUOX1,ATP1A1,IDE,PTPRJ,RBL1,ADAMTS14,EFNA5,IRF7,ST3GAL1,LTA4H,AIFM3,ZNF701,NDST3,MAN2B2,ZMAT1,CMAS,COL9A3,PACSIN2,CDH22,RUSC2,GNE,GABRG2,GDF15,NKRF,CRABP2,DSE,AIP,VPS26A,SLC9A2,PPP2R3A,NRP2,SIRPA,FZD6,SH2D4A,FOXP2,ALPP,GTF2F2,FAM63A,TSPAN13,BUB1,SYK,ATP2B1,GCNT1,FAH,IGDCC4,HMMR,DLGAP1,RHOA,FBLN5,IFITM3,GUSB,NR3C1,AMFR,PPARA,PRICKLE1,COL7A1,PELI3,TXNDC11,BSDC1,PRDX4,FUCA1,FAT4,SCG2,ZNF214,NMI,TMC5,NETO2,CLIP4,FAM117A,PPP2R3C,SH3BGRL2,ICOSLG,TBC1D4,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,DIS3L,LAMP1,SUN1,GAA,PPP4R4,LGR4,HSPG2,SSH1,ATP8A1,PSME1,CCNB1,PJA2,OAT,SLC20A1,FAM101B,SLC9A7,NCS1,SESN3,CTGF,RGS3,OSBPL3,PRICKLE3,FOSB,SERINC2,AOX1,PIK3CA,KCNS3,STEAP2,ATRNL1,SNX16,IQCD,HYLS1,PACSIN1,XKR8,METAP2,ORAI2,TMEM68,SPATA18,HSPA12A,KIF13A,TNS1,PIF1,LDB2,POR,AHRR,SLC25A4,PLK2,GNPTAB,LRIG1,NKD1,BMP1,DHTKD1,SERPINI1,EIF4EBP2,NFKBIZ,TANC2,WBSCR27,TRAF5,F2RL1,LZTS1,DDX58,SEMA6B,MRC2,CDK17,FRMD4A,TBC1D1,DGKQ,KIF23,C6orf106,ISYNA1,PSIP1,PRRG4,MESDC2,MECOM,C9orf69,DOPEY2,RALGPS2,ITGA3,PIK3AP1,BHLHE41,SLC16A6,AIM1,BDH1,RUNDC3B,DAPK1,PRKG1,SORL1,OSTF1,CACNA1D,RIMS2,FAM69A,IGSF3,EPB41L5,GFPT1,PMPCB,KCNJ12,B3GNT7,MFI2,PRSS23,TBC1D8B,ANO6,ANTXR1,GLT8D2,RASA1,MMP15,DGKH,GABRD,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,SLC4A3,AGBL5,PCDH19,CABIN1,PER3,MAP3K5,IFIH1,NRBP1,FRMPD3,PLA2G4A,SPRED1,SLC2A4,TCTN2,REPS2,DLGAP5,TRIP10,S100A11,ST14,NLRX1,BROX,IQGAP1,CAST,RALBP1,THRA,ATP2C2,KCTD12,RNF182,CD274,MNS1,ZFYVE9,APLP2,ACAP2,FAM46A,TRANK1,CNNM4,DAB2IP,IFIT1,PDE4D,EPHB4,LGMN,NR2C1,NAGA,GPX4,MYO5B,DOCK4,COG2,CAPN6,PANK1,UTRN,KIF1C,PRKCQ,PKMYT1,PYGO1,C15orf39,ITPR3,ALCAM,ATP10D,CMTM7,NIN,AMZ2,DDOST,POPDC3,PPP2R5A,JAK1,TSPAN18,ZNF704,SLC27A1,NRG1,MLKL,HS3ST3B1,SLC27A3,NR3C2,COBL,DENND5B,WASF3,ARHGEF3,PCOLCE,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,SEPP1,DNAH3,SIX4,LGALS3BP,SCML1,WWP2,AKIRIN1,E2F7,FAM111A,RNF128,PHF7,PTEN,FUT8,FJX1,SGK3,ATP8B1,ERBB3,SPRY2,SLC16A5,NCOA2,OSGIN1,FARP2,RASGRF1,TGIF1,ZWINT,ARHGEF28,ERMAP,LONRF3,MPP1,PARP4,ZKSCAN2,DIAPH2,FBXO9,GRTP1,AIF1L,FOS,ARSK,KIF11,GPLD1,CDK5RAP1,MAMDC4,TBX18,ABCB1,PGM2L1,WDR62,NCAPG2,CPEB2,ESPL1,JARID2,RGMA,ESYT2,EXPH5,LTBP1,CASP3,UGT8,CAMKK1,VARS2,MPP5,DNER,CACNB4,KREMEN1,TMC1,PTCHD4,CHPF,ARHGEF10L,ZFYVE16,SIPA1L2,LRRC6,GRHL1,ZCCHC12,ARHGEF37,DPYSL2,CEP78,ANKFN1,DLG1,POF1B,ANKRD12,TRPC1,SUN3,TECR,SLC39A10,PTPRE,MYRIP,BTBD3,CYP1B1,LAMP3,ITCH,RGAG1,ARHGDIB,ROR1,PTGFRN,MAN2A2,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,MADD,ZNF165,SP6,RAP1GAP,CPPED1,PCSK5,GRN,ARAP3,PEX6,BVES,ETV5,ABCG2,CALM3,PM20D2,FAM81A,PHLPP1,ADAMTSL4,ZNF432,CA2,COL6A1,LIMCH1,C10orf54,RFX5,SLC12A2,ETV7,CCDC88A,SNX7,MDFI,KDELR1,PODXL2,OXR1,GYLTL1B,VWA1,PDE5A,BTN3A2,HEATR5A,NUBP1,AMDHD1,RANBP9,MUM1L1,SOX13,GNAS,XKRX,ONECUT1,SLC6A6,UAP1,TMEM30A,CGREF1,ALPK3,RHOBTB2,SHROOM2,JAK3,COL16A1,AFAP1,RARG,PROM2,KLF7,CCNE2,NCKAP5,SLC25A24,SORBS1,FAM92A1,PDIA5,COL18A1,IL27RA,MRAS,TDRKH,PHLDA1,ARHGEF16,KCTD9,SS18,ZNF687,KIF14,FRYL,REEP1,TWIST1,EPB41L4B,ECE1,PDIA6,ZNF525,PTPRU,ERBB2IP,DOCK5,CASP4,ARHGAP35,ALDH5A1,BHLHB9,TLE1,PTBP3,OVOL1,SPTBN5,CYP2U1,ABCA1,PPP2R2D,LIFR,GCLM,SORT1,ARHGEF11,FRMD6,MIER3,TGFBR1,COL4A5,NOTUM,INTS8,TRIB2,POMGNT1,SBF1,HMGXB4,SAC3D1,HDAC9,TOP2A,IRF2BPL,MDM1,ADORA1,TAF1B,MLPH,LLGL2,A4GALT,BMP7,TOX2,RRBP1,KIAA0319,IQGAP3,CLIP2,MYO5A,PGM1,PHF20L1,SUN2,NR4A1,ASPM,RC3H2,MBNL3,LRRC66,RUNX3,LEPR,KLHL2,ARHGAP24,TRIM69,DHRS2,UACA,ARRB1,GRAMD1C,HOXB13,ZMIZ1,SOX8,GEM,AHR,RAB3IL1,ABCG1,SNPH,CD33 |
| 1.313e-03 | -6.64 | hyperplasia | COSMIC cancer mutations | hyperplasia | 52 | 13 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,IL6ST,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 1.313e-03 | -6.64 | GTPase binding | molecular function | GO:0051020 | 265 | 43 | 16491 | 1673 |
EXPH5,PIFO,RALBP1,RUSC2,IQGAP1,EPS8,SYTL4,NCKAP1,PKN1,ARHGEF16,SYTL2,RABGGTA,ACAP2,MLPH,LLGL2,RANBP1,EXOC8,SORL1,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,STRADB,DIAPH2,RANBP9,RASA1,OPTN,RAB11FIP2,CORO1C,SH3BP4,TRIOBP,RAB11FIP1,FGD6,ITPKA,RAP1GAP,ABCA1,DOCK9,EHD1,FGD1 |
| 1.320e-03 | -6.63 | Ion transport by P-type ATPases | REACTOME pathways | R-HSA-936837 | 49 | 13 | 8202 | 867 |
ATP1A1,ATP9A,ATP7B,ATP8A1,FXYD3,ATP2C2,ATP8B1,ATP8B3,ATP1B1,ATP1B3,ATP10D,ATP2B1,ATP13A2 |
| 1.321e-03 | -6.63 | embryonic organ development | biological process | GO:0048568 | 423 | 63 | 16441 | 1675 |
CTHRC1,TNRC6C,RUNX2,GRHL2,CDKN1C,HSPG2,HOXB7,EPAS1,ST14,THRA,SOX9,TP53,TGFBR1,OSR2,NCKAP1,STIL,PDGFB,HOXB2,SIX4,FZD6,PDGFA,E2F7,SETDB2,CYR61,GATA2,MEGF8,BMP7,ALDH1A3,DLG1,TFAP2A,PLK4,TWIST1,WNT3A,CITED2,SPRY2,DVL2,MDFI,HES1,SPEF2,AKT1,SCRIB,PRKRA,NPHP3,ABR,SOCS3,GNAS,HS6ST1,NCOA3,FGFR2,PTK7,TBX18,LRIG1,SPINT2,TRAF3IP1,NR4A3,FZD5,OSR1,GAB1,E2F8,COBL,RARG,PCSK5,EGLN1 |
| 1.324e-03 | -6.63 | negative regulation of cell motility | biological process | GO:2000146 | 203 | 35 | 16441 | 1675 |
TCAF1,ARAP3,NF2,ADGRG1,PKP2,VASH1,FBLN1,NOV,SVBP,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,CITED2,CYP1B1,PTPRU,ACVR1C,RGCC,PTGER4,ARHGDIB,EPHA1,DAG1,ABR,DPYSL3,AP1AR,PTPRJ,ACVRL1,CORO1C,RAP2C,SPINT2,NRG1,EGFL7,SEMA3A |
| 1.325e-03 | -6.63 | Semaphorin interactions | REACTOME pathways | R-HSA-373755 | 67 | 16 | 8202 | 867 |
MYL9,DPYSL5,RHOA,ARHGEF11,ERBB2,PLXNA1,CDK5R1,ARHGAP35,DPYSL3,SEMA4D,LIMK1,DPYSL2,MYH14,SEMA3A,MYL12B,FARP2 |
| 1.326e-03 | -6.63 | CATATPASE | prints domains | PR00119 | 35 | 10 | 4759 | 462 |
ATP1A1,ATP9A,ATP7B,ATP8A1,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.327e-03 | -6.63 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | 193 | 33 | 17758 | 1761 |
WASF3,SIGIRR,LGR4,CKAP2,ABCG2,CALM3,TDRKH,SEPP1,MERTK,C11orf95,STIL,FANCI,IL17RB,CALM2,TOP2A,CNTRL,BUB1,TSPAN13,RASGRP1,FAM69A,CKS2,PGM1,STAT4,CALM1,PTGER4,ARHGDIB,LRRC1,KIF11,KCNMB4,SEMA4D,INPP4B,STK39,EHD1 |
| 1.327e-03 | -6.63 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | 193 | 33 | 17758 | 1761 |
SUN1,CAST,FAM134A,EFHD2,TEX2,DPP8,SLC25A36,ATG4A,RCN1,DOPEY2,XYLT2,DLG1,PPP6R1,ADCK3,PIP4K2C,STMN3,EPHA1,DNAJB14,ERBB2IP,DAG1,MAN2A2,MMP15,AMZ2,AP1AR,POPDC3,LIMK1,FAM117A,CABIN1,MRPS28,NDE1,TMEM14A,PCSK5,DOCK9 |
| 1.327e-03 | -6.63 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | 193 | 33 | 17758 | 1761 |
MYL9,CD99,UGP2,ALDH6A1,MRPS15,HEBP1,CAST,PBX3,NDRG2,NENF,PSME1,DPP8,REPS1,HMGXB4,ARHGEF10L,PDGFA,FAM46A,DLG1,CTTN,NCAM1,NCOA2,MMD,HTATIP2,PRKAR2B,KIF11,SLC25A5,ENDOD1,MFAP3L,DNM1L,PTER,PGRMC1,FHL1,NRGN |
| 1.327e-03 | -6.63 | GSE22886_DC_VS_MONOCYTE_UP | MSigDB lists | GSE22886_DC_VS_MONOCYTE_UP | 193 | 33 | 17758 | 1761 |
MYL9,MRC2,AVPI1,EPAS1,NENF,MPP5,ISYNA1,LMNA,CTSC,MGAT4A,COL6A1,ADCK2,GOT1,ALDH3A2,FAM69A,ZWINT,HMG20B,TNS1,ATP1B1,SESN1,ABR,GABARAPL1,BCAR3,ALDH5A1,SWAP70,TWSG1,SPINT2,DONSON,MDH1,RAP1GAP,HSPB1,SLC27A3,ACOT7 |
| 1.329e-03 | -6.62 | YEGNASUBRAMANIAN_PROSTATE_CANCER | MSigDB lists | YEGNASUBRAMANIAN_PROSTATE_CANCER | 119 | 23 | 17758 | 1761 |
NKX3-1,ALDH6A1,SLC39A8,NDC80,KIF23,CENPN,TRIM68,ARHGEF26,FECH,SERPINA1,DHRS2,ELF5,GTF2F2,CLDN4,DONSON,HOXB13,ERBB3,MYBL1,ALDH3A2,OCLN,MCCC2,GCNT1,CTH |
| 1.329e-03 | -6.62 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 119 | 23 | 17758 | 1761 |
GOLIM4,NQO1,TBC1D1,HLA-F,ARL4C,PPP1R14C,AIFM2,PHLDA1,ETS1,TP53I3,SH3KBP1,LMNA,MECOM,ARHGAP24,PDGFA,HLA-B,PPP4R1,TFAP2A,ABCB1,SERPINI1,HLA-C,MAP3K5,SERPINB1 |
| 1.334e-03 | -6.62 | DER_IFN_GAMMA_RESPONSE_UP | MSigDB lists | DER_IFN_GAMMA_RESPONSE_UP | 71 | 16 | 17758 | 1761 |
PLSCR1,IL15RA,HLA-E,TAP1,PSME1,IFIT3,PHLDA1,HLA-A,FAS,ATP6V0B,PLOD2,NMI,VAT1,TRIM21,HLA-C,COL16A1 |
| 1.335e-03 | -6.62 | Ets | pfam domains | PF00178 | 28 | 9 | 16629 | 1696 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7,ELF3 |
| 1.338e-03 | -6.62 | peritoneum-mesothelioma | COSMIC cancer mutations | peritoneum-mesothelioma | 46 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.339e-03 | -6.62 | protein disulfide isomerase activity | molecular function | GO:0003756 | 23 | 8 | 16491 | 1673 |
ERO1A,TMX4,PDIA5,PDIA3,TXNDC11,ERP29,PDIA6,PDIA4 |
| 1.339e-03 | -6.62 | intramolecular oxidoreductase activity, transposing S-S bonds | molecular function | GO:0016864 | 23 | 8 | 16491 | 1673 |
ERO1A,TMX4,PDIA5,PDIA3,TXNDC11,ERP29,PDIA6,PDIA4 |
| 1.342e-03 | -6.61 | MODULE_121 | MSigDB lists | MODULE_121 | 98 | 20 | 17758 | 1761 |
GRN,IL15RA,IL15,EPS8,ERBB2,IL18,RUNX3,PDGFB,BCAR1,TNFSF9,CDK5R1,EDNRA,MDK,PDGFA,CYR61,CSF1,BCL6,TACSTD2,EPHB4,LAMP3 |
| 1.342e-03 | -6.61 | CAHOY_ASTROCYTIC | MSigDB lists | CAHOY_ASTROCYTIC | 98 | 20 | 17758 | 1761 |
PAPSS2,LPGAT1,RASA2,PANK1,PPARA,RGS20,MERTK,TNFRSF19,TTYH3,KIAA1161,ATP1A1,GRHL1,CYP4F11,CORO1C,ELF5,TMEM51,FGD6,SLC27A1,NCEH1,AIFM3 |
| 1.343e-03 | -6.61 | negative chemotaxis | biological process | GO:0050919 | 39 | 11 | 16441 | 1675 |
PDGFA,SEMA6B,RHOA,SEMA4D,FLRT3,NRG1,EFNA5,ITGAV,SEMA3G,SEMA3A,SEMA3B |
| 1.347e-03 | -6.61 | Downstream signaling events of B Cell Receptor (BCR) | REACTOME pathways | R-HSA-1168372 | 168 | 31 | 8202 | 867 |
TNRC6C,PSMB4,NFKBIE,AKT1,NR4A1,PSME2,CASP9,PIK3R1,PSMD10,ERBB2,NRG2,AGO4,PSME1,PHLPP1,PDGFB,PSMA4,FGF19,PDGFA,IRS2,PSMD1,PTEN,FGFR2,PHLPP2,NFKBIA,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1,RASGRP1 |
| 1.349e-03 | -6.61 | VERHAAK_AML_WITH_NPM1_MUTATED_UP | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_UP | 178 | 31 | 17758 | 1761 |
PLA2G4A,LTBP1,SORT1,MCTP1,PLAUR,CAST,SAT1,PBX3,COL4A5,GDF15,PRKAR2B,SEPP1,PHLDA1,HOXB2,LGALS3BP,LMNA,IER3,GNS,TYMP,SERPINA1,ETS2,NGFRAP1,HOXA9,SLC2A6,SECTM1,NFKBIA,BCL6,PHKA2,SNX10,S100A6,CYP1B1 |
| 1.352e-03 | -6.61 | regulation of metal ion transport | biological process | GO:0010959 | 327 | 51 | 16441 | 1675 |
PRSS8,SCN5A,SERPINE2,LGALS3,CD63,FXYD3,UBASH3B,CACNA2D2,CALM3,PKP2,PRKACA,CACNB4,PDGFB,WWP2,KIF5B,CALM2,SNTA1,NKAIN3,ADORA1,GNB5,STIM1,CABP1,PLCG2,SGK3,DLG1,BAX,SGK1,TRPC1,FXYD5,TSPAN13,PDE4D,CACNA1D,F2R,MYO5A,CHP1,KCNIP3,RHOA,AKT1,CALM1,UTRN,ATP1B1,PLCG1,ATP1A1,WFS1,SARAF,CAB39,STK39,GPER1,FHL1,ATP1B3,JAK3 |
| 1.352e-03 | -6.61 | Ca2+ pathway | REACTOME pathways | R-HSA-4086398 | 61 | 15 | 8202 | 867 |
CALM2,TNRC6C,GNB5,FZD4,CALM1,ITPR1,PRKG1,CALM3,AGO4,TCF7,ITPR2,FZD5,ITPR3,PLCB2,FZD6 |
| 1.353e-03 | -6.61 | PID_PTP1B_PATHWAY | MSigDB lists | PID_PTP1B_PATHWAY | 52 | 13 | 17758 | 1761 |
TXN,RHOA,AKT1,CSF1,PIK3R1,PIK3CA,YES1,BCAR1,PDGFB,SPRY2,LEPR,CAPN1,SOCS3 |
| 1.353e-03 | -6.61 | KEGG_ENDOMETRIAL_CANCER | MSigDB lists | KEGG_ENDOMETRIAL_CANCER | 52 | 13 | 17758 | 1761 |
CCND1,AKT1,CDH1,PTEN,CASP9,PIK3R1,PIK3CA,TP53,ERBB2,TCF7,PIK3CD,ELK1,APC2 |
| 1.353e-03 | -6.61 | TRAYNOR_RETT_SYNDROM_UP | MSigDB lists | TRAYNOR_RETT_SYNDROM_UP | 40 | 11 | 17758 | 1761 |
PLA2G4A,LTBP1,CALD1,PRICKLE1,RNF182,NTN4,SNTB1,FBLN1,TNFRSF19,ANKRD29,SYTL2 |
| 1.353e-03 | -6.61 | PID_FOXM1_PATHWAY | MSigDB lists | PID_FOXM1_PATHWAY | 40 | 11 | 17758 | 1761 |
CCND1,PLK1,ONECUT1,CENPA,FOXM1,ETV5,NEK2,CCNB1,CCNB2,FOS,CDK1 |
| 1.353e-03 | -6.61 | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | 40 | 11 | 17758 | 1761 |
LASP1,SLC37A1,NFKBIE,SH3BP1,ANO6,AIM1,CTDSPL,BCL2L1,PRKRA,CCDC88A,FARP2 |
| 1.354e-03 | -6.61 | SNTB1 (syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)) | protein interactions | 6641 | 13 | 6 | 16036 | 1726 |
KCNJ12,SCN5A,SAV1,ABCA1,MAPK12,UTRN |
| 1.357e-03 | -6.60 | CAPN2 (calpain 2, (m/II) large subunit) | protein interactions | 824 | 54 | 14 | 16036 | 1726 |
MAN2A2,B3GNT2,ADRBK1,STK26,PAPSS1,NFKBIA,CASP9,ALDH7A1,TNS1,F2RL1,CDK5R1,DCP2,CTH,PDIA4 |
| 1.360e-03 | -6.60 | regulation of microvillus assembly | biological process | GO:0032534 | 6 | 4 | 16441 | 1675 |
ATP8B1,KLF5,PLD1,RAP1GAP |
| 1.360e-03 | -6.60 | protection from natural killer cell mediated cytotoxicity | biological process | GO:0042270 | 6 | 4 | 16441 | 1675 |
HLA-B,HLA-E,HLA-A,TAP1 |
| 1.364e-03 | -6.60 | glycosylation | biological process | GO:0070085 | 351 | 54 | 16441 | 1675 |
CMAS,GALNT12,GNE,PDIA3,CTSZ,NANS,MGAT5B,B4GALT4,POMGNT1,ADAMTSL4,B4GALNT1,B3GALNT1,MUC16,FUT2,MUC4,CTSC,A4GALT,ALG13,MGAT4A,FUT8,FUT1,UBE2J1,RPN2,LMAN1,TIPARP,MGAT5,PPP6R1,GCNT1,TRAK2,GFPT1,SIRT1,B3GALT6,SEC23A,B3GNT7,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,SLC35C1,COL7A1,GALNT7,MCFD2,ARF4,GALNT3,FUCA1,MAN2A2,UAP1,SERPINA1,DDOST,DOLPP1,GNPTAB,CTSA,ST3GAL1 |
| 1.366e-03 | -6.60 | Kinesin_assoc | pfam domains | PF16183 | 6 | 4 | 16629 | 1696 |
KIF1C,KIF13A,KIF14,KIF13B |
| 1.366e-03 | -6.60 | homeostatic process | biological process | GO:0042592 | 1343 | 170 | 16441 | 1675 |
EMX1,CASP3,GAA,TXN,ADD1,LGR4,EPAS1,HEXB,TAP1,CACNB4,BARD1,SLC8B1,SLC9A7,SESN3,PQLC2,MUC4,CTGF,SIVA1,IL31RA,STEAP2,PIK3CA,ABCA2,AKR1B1,CLDN4,TRPC1,CRY2,RAB20,PIK3CD,ACOX2,ZBTB18,SLC39A10,CD55,NFE2L1,PRKAR2B,PIF1,LDB2,PRIM1,EDNRA,ENPP1,GPRC5B,ATP7B,NOD2,ADIPOR1,HSPB1,F2RL1,PRKAA2,CALB2,SOX9,MTL5,ABCG2,SLC25A27,MECOM,CA2,GATA2,KCNN4,MYLIP,SLC12A2,SLC37A1,MFI2,ANO6,ERO1A,GYLTL1B,EIF2AK1,NPC2,PDK3,NPHP3,TP53INP2,NUBP1,SFXN5,STEAP1,FAS,GNAS,FECH,SLC4A4,CSF1,ITPR1,SLC4A3,ATP1B3,CCNB2,JAK3,EGLN1,EHD1,MTM1,CCDC109B,SLC2A4,THRA,TMX4,ATP2C2,PDIA5,PKP2,FTH1,PRKACA,BCAP31,ATP6V0B,APLP2,NOV,SCNN1A,SP100,PLCG2,BCL6,CNNM4,CDH3,GOT1,TMEM64,IFIT1,PDIA6,MYT1,F2R,CHP1,MYO5B,SIRT1,CLCN3,AKT1,ACO1,SLC11A2,ATP1B1,RAB38,ITPR3,CD40,ATP13A2,IRS2,DNAJC10,IDE,ATP1A1,AXL,SLC9A6,WFS1,PEX2,INPP4B,PTBP3,AIFM3,ABCA1,POC1B,PDIA3,PKN1,GSTP1,SLC9A2,NEO1,PDIA4,ADORA1,BAX,SGK3,SGK1,TMBIM6,ATP2B1,LCA5,GCLC,PIK3R1,EIF5A2,RC3H2,GRIN1,TTC7A,TXNDC11,BBS2,PRDX4,SWAP70,ACADSB,RAB11FIP2,NR1D2,PRCP,NR4A3,PPP2R3C,LRRK1,MCUR1,GPER1,NDFIP1,SLC25A38,USF2,CYBRD1,ABCG1 |
| 1.376e-03 | -6.59 | MELLMAN_TUT1_TARGETS_DN | MSigDB lists | MELLMAN_TUT1_TARGETS_DN | 46 | 12 | 17758 | 1761 |
CCNE2,ALDH2,KLF12,NQO1,ALDH1A3,KLF5,KLF9,PACSIN1,SCARA3,SNX10,TXNDC11,KLF7 |
| 1.376e-03 | -6.59 | SIG_BCR_SIGNALING_PATHWAY | MSigDB lists | SIG_BCR_SIGNALING_PATHWAY | 46 | 12 | 17758 | 1761 |
AKT1,INPP5D,PLCG2,ITPR1,PIK3R1,PIK3CA,CR2,PIK3CD,ITPR2,ITPR3,DAG1,SYK |
| 1.377e-03 | -6.59 | heparan sulfate proteoglycan biosynthetic process | biological process | GO:0015012 | 23 | 8 | 16441 | 1675 |
B3GALT6,HS6ST1,XYLT2,XYLT1,HS3ST3B1,DSE,NDST3,GLCE |
| 1.377e-03 | -6.59 | Znf_hrmn_rcpt | interpro domains | IPR001628 | 46 | 12 | 18293 | 1814 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 1.379e-03 | -6.59 | Cell adhesion molecules (CAMs) | KEGG pathways | hsa04514 | 142 | 28 | 6908 | 758 |
CD99,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,CD40,SDC1,ALCAM,HLA-A,NEO1,PTPRF,CNTNAP1,HLA-B,CDH1,ITGB8,PVRL2,CDH3,CLDN4,HLA-C,ITGAV,ICOSLG,NCAM1,L1CAM,OCLN |
| 1.379e-03 | -6.59 | Cell adhesion molecules (CAMs) | KEGG pathways | ko04514 | 142 | 28 | 6908 | 758 |
CD99,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,CD40,SDC1,ALCAM,HLA-A,NEO1,PTPRF,CNTNAP1,HLA-B,CDH1,ITGB8,PVRL2,CDH3,CLDN4,HLA-C,ITGAV,ICOSLG,NCAM1,L1CAM,OCLN |
| 1.379e-03 | -6.59 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | 14 | 6 | 17775 | 1757 |
ERBB2,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.379e-03 | -6.59 | juvenile_xanthogranuloma | COSMIC cancer mutations | juvenile_xanthogranuloma | 14 | 6 | 17775 | 1757 |
ERBB2,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.384e-03 | -6.58 | Glioma | KEGG pathways | hsa05214 | 65 | 16 | 6908 | 758 |
AKT1,PIK3R1,CALM1,TP53,CALM3,PDGFB,CALM2,CCND1,PDGFA,PLCG1,IGF1R,PTEN,SHC3,PLCG2,PIK3CA,PIK3CD |
| 1.384e-03 | -6.58 | Glioma | KEGG pathways | ko05214 | 65 | 16 | 6908 | 758 |
AKT1,PIK3R1,CALM1,TP53,CALM3,PDGFB,CALM2,CCND1,PDGFA,PLCG1,IGF1R,PTEN,SHC3,PLCG2,PIK3CA,PIK3CD |
| 1.402e-03 | -6.57 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | 186 | 32 | 17758 | 1761 |
RUNX2,KIAA1462,ARMCX3,LGALS3,EPAS1,PSME2,PPP2R3A,PLS3,TOX2,PLEKHF1,RAB20,F2R,C12orf75,XKR8,ABCC1,SUSD3,SEC61B,STAU2,LPGAT1,GGH,RNF19B,RNPEP,CASP4,FRMD4B,ENPP1,GNPTAB,ITPR1,RYK,MLKL,GEM,AHR,EHD1 |
| 1.402e-03 | -6.57 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | 186 | 32 | 17758 | 1761 |
ANXA3,ARAP3,TXN,S100A11,CD63,EFHD2,ARHGEF40,TSEN34,IER3,CTSC,PPP4R1,SORL1,IFIT1,ECE1,S100A6,CKAP4,XKR8,LAMP2,GCA,IFITM3,LITAF,IFIT3,CASP4,STX3,FAS,SERPINA1,PPP2R5A,SEMA4D,SECTM1,NMI,IFI6,CPPED1 |
| 1.402e-03 | -6.57 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 186 | 32 | 17758 | 1761 |
CASP3,NFKBIE,MMADHC,DSE,OAT,EPS8L2,DNAJB9,SGPL1,ZFYVE16,MITF,TPST1,TNFRSF12A,SOCS5,DOCK4,LAMP2,RAPGEF2,CORO2A,COQ10B,AK4,FNDC3A,RHEB,FAS,DUOX1,PRKAG2,C19orf66,S100A5,ZNF165,ESPL1,MYL12B,EHD1,NXT2,JARID2 |
| 1.402e-03 | -6.57 | GSE29618_PDC_VS_MDC_UP | MSigDB lists | GSE29618_PDC_VS_MDC_UP | 186 | 32 | 17758 | 1761 |
LAMP1,RUNX2,CRYM,ATP8A1,NUCB2,SLC20A1,ETS1,DAPK2,RAB15,RPS6KA2,CTSC,RIMS3,RRBP1,UBE2J1,TSPAN13,EGLN3,LMAN1,SCYL3,SEPHS1,SEC61B,SYNE2,MYBL2,NPC2,LHFPL2,CDK5R1,PIAS3,MAPKAPK2,SCARB2,DCK,CCDC69,IRF7,TBC1D4 |
| 1.403e-03 | -6.57 | ROETH_TERT_TARGETS_UP | MSigDB lists | ROETH_TERT_TARGETS_UP | 14 | 6 | 17758 | 1761 |
PLA2G4A,HERC5,MX1,IFIT1,IFIT3,HERC6 |
| 1.403e-03 | -6.57 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | MSigDB lists | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | 14 | 6 | 17758 | 1761 |
DPYSL5,PLXNA1,SEMA3A,DPYSL2,CDK5R1,DPYSL3 |
| 1.403e-03 | -6.57 | positive regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014068 | 57 | 14 | 16441 | 1675 |
PDGFA,NKX3-1,PIK3AP1,SEMA4D,SOX9,ERBB2,NRG1,GPER1,ERBB3,MYDGF,UNC5B,PDGFB,F2R,F2RL1 |
| 1.403e-03 | -6.57 | phospholipid transport | biological process | GO:0015914 | 57 | 14 | 16441 | 1675 |
ATP9A,MFSD2A,KCNN4,ATP8A1,TMEM30A,ATP8B1,PITPNA,NPC2,ATP8B3,PCTP,CPTP,ATP10D,ABCA1,ABCG1 |
| 1.405e-03 | -6.57 | hair follicle development | biological process | GO:0001942 | 76 | 17 | 16441 | 1675 |
LGR4,LRP4,SOX9,TFAP2C,SAV1,LDB2,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,DBI,CTSV,HDAC1,HOXC13 |
| 1.405e-03 | -6.57 | regulation of protein depolymerization | biological process | GO:1901879 | 76 | 17 | 16441 | 1675 |
GAS2L1,ADD1,CKAP2,EPS8,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2,F2RL1 |
| 1.405e-03 | -6.57 | MAPK8 (mitogen-activated protein kinase 8) | protein interactions | 5599 | 179 | 33 | 16036 | 1726 |
CASP3,BMF,SCOC,RET,TP53,IL27RA,BCL2L1,GSTP1,HDAC9,CDKN2C,APLP2,DUSP10,CDKN1B,GFPT1,SIRT1,SUN2,RHOA,ELK3,AKT1,NR3C1,NR4A1,ITCH,PIK3R1,EZR,PKMYT1,ELK1,DUSP4,BCAR1,MAPK8IP1,FAS,NCOA3,HDAC1,WDR62 |
| 1.413e-03 | -6.56 | CSR_LATE_UP.V1_DN | MSigDB lists | CSR_LATE_UP.V1_DN | 156 | 28 | 17758 | 1761 |
FADS2,DDB2,C6orf1,NFKBIE,PYROXD2,TSC22D3,PDE5A,FTH1,DUSP4,SNTB1,GLT8D2,ANKRD29,POR,SCML1,IRS2,PGF,NOV,ITGB8,ACVRL1,SNX18,CALD1,LRIG1,DRAM1,PRKG1,NTN4,C10orf54,L1CAM,IGDCC4 |
| 1.416e-03 | -6.56 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | 256 | 41 | 17758 | 1761 |
IER5L,ACACB,ARHGEF3,AVPI1,ARAP3,FRMD4A,ZNF395,CDKN1C,CNOT8,NDRG2,SLC20A1,SDC1,ARHGEF40,KREMEN1,CDS1,MUC16,SETDB2,SLC27A6,SNX18,SHC3,REEP1,TACSTD2,C10orf54,CITED2,SPRY2,SUSD3,SMARCA2,MBP,PRICKLE1,PDE5A,LRRC1,XRCC6BP1,FANCE,STEAP1,FAM64A,OTUB2,RHOBTB2,ZNF165,AURKA,NDE1,SLC25A30 |
| 1.418e-03 | -6.56 | MODULE_243 | MSigDB lists | MODULE_243 | 78 | 17 | 17758 | 1761 |
TM2D2,PDCL,PSMD10,SLC11A2,NDUFA4,FAM198B,BCL2L1,RAD17,PJA2,LBR,TSPAN7,M6PR,PDGFA,AMZ2,TSPAN6,EGFL7,TOB1 |
| 1.418e-03 | -6.56 | HUANG_DASATINIB_RESISTANCE_UP | MSigDB lists | HUANG_DASATINIB_RESISTANCE_UP | 78 | 17 | 17758 | 1761 |
PGM1,PDGFC,ELK3,IL15RA,CAST,NDC80,BTN3A2,KCTD12,IFIT3,SH3KBP1,ST5,POPDC3,CALD1,DUSP10,FXYD5,F2RL1,SOCS5 |
| 1.418e-03 | -6.56 | BHAT_ESR1_TARGETS_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_DN | 78 | 17 | 17758 | 1761 |
CPEB4,SNTB2,EPS8,BCL2L1,ATP1B1,SYTL2,BCAR3,SHROOM3,GRHL1,CDH3,ZDHHC7,TLE1,PLEKHF1,KLF9,SLC16A5,RARG,IGSF3 |
| 1.418e-03 | -6.56 | Galactose-bd-like | interpro domains | IPR008979 | 78 | 17 | 18293 | 1814 |
GUSB,EPHA4,FURIN,FBXO2,FBXO6,EPHA1,CNTNAP2,DDR1,NRP2,CNTNAP1,EPHA10,SUCO,GLB1L2,EPHB4,FBXO27,DCBLD1,PCSK5 |
| 1.419e-03 | -6.56 | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | MSigDB lists | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | 171 | 30 | 17758 | 1761 |
CCNE2,UPF3B,FAM199X,CENPI,NUF2,B4GALT4,NUP62CL,BARD1,PDIK1L,CDK1,PSIP1,MECOM,ELF3,SCML1,KLHL2,E2F7,ETS2,NR1D2,RBL1,ZNF367,HOXA9,PRPS2,NEK2,ATP8B1,NR4A2,DONSON,GRAMD1C,PER3,DDX59,E2F8 |
| 1.421e-03 | -6.56 | JOHNSTONE_PARVB_TARGETS_2_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_UP | 134 | 25 | 17758 | 1761 |
IGFBP6,S100A11,CALM1,TP53,FURIN,CALM3,BCL2L1,IFIT3,PKN1,AIF1L,CMTM6,HLA-A,CALM2,MDK,HLA-B,APLP2,AGPAT2,PVRL2,H1F0,ALDH1A3,FXYD5,AKR1B1,IFIT1,C10orf54,CITED2 |
| 1.432e-03 | -6.55 | PDZ domain binding | molecular function | GO:0030165 | 83 | 18 | 16491 | 1673 |
DOCK4,CLCN3,FZD4,CIT,RAPGEF2,F11R,SNTB1,ARHGEF16,FZD7,SNTA1,CXXC4,LLGL2,PTEN,KIF14,NKD1,SRR,DLG3,ATP2B1 |
| 1.442e-03 | -6.54 | CTTTGTA,MIR-524 | MSigDB lists | CTTTGTA,MIR-524 | 419 | 61 | 17758 | 1761 |
MTM1,CTHRC1,SORT1,LRRFIP2,ADD1,LGR4,CPEB4,HOXB7,IQGAP1,ATP8A1,DCAF7,SOX9,CACNA2D2,PDCL,C5orf30,NKRF,SLC1A3,SIPA1L2,CPNE2,RNF220,ITGA3,LYPD3,WDR44,KCNN4,LMO4,LHX6,MITF,PTPRE,SP5,ATP2B1,IGDCC4,LAMP2,SSH3,HES1,PHF20L1,MOSPD2,PTPRU,STAT4,PRICKLE1,ERBB2IP,GALNT7,PRKRA,SESN1,RANBP9,SP4,BSDC1,NFIX,IRS2,NCOA3,SLC6A6,ETS2,P4HA2,NR4A3,HDAC1,ADIPOR1,NR4A2,SOX8,ZMIZ1,CPEB2,ABCA1,HOXC13 |
| 1.445e-03 | -6.54 | Viral carcinogenesis | KEGG pathways | ko05203 | 205 | 37 | 6908 | 758 |
CCNE2,CASP3,HLA-E,HLA-F,RASA2,HDAC11,TP53,HDAC6,PRKACA,HLA-A,HDAC9,CCND1,SP100,IL6ST,RANBP1,DLG1,BAX,PIK3CA,CDKN1B,PIK3CD,HLA-C,SYK,RHOA,PIK3R1,CDC20,SCRIB,GTF2A2,CDK1,MAPKAPK2,HLA-B,JAK1,RBL1,NFKBIA,HDAC1,IRF7,JAK3,TRAF5 |
| 1.445e-03 | -6.54 | Viral carcinogenesis | KEGG pathways | hsa05203 | 205 | 37 | 6908 | 758 |
CCNE2,CASP3,HLA-E,HLA-F,RASA2,HDAC11,TP53,HDAC6,PRKACA,HLA-A,HDAC9,CCND1,SP100,IL6ST,RANBP1,DLG1,BAX,PIK3CA,CDKN1B,PIK3CD,HLA-C,SYK,RHOA,PIK3R1,CDC20,SCRIB,GTF2A2,CDK1,MAPKAPK2,HLA-B,JAK1,RBL1,NFKBIA,HDAC1,IRF7,JAK3,TRAF5 |
| 1.446e-03 | -6.54 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | MSigDB lists | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 29 | 9 | 17758 | 1761 |
MYL9,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,ARHGAP35 |
| 1.446e-03 | -6.54 | DORN_ADENOVIRUS_INFECTION_12HR_UP | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_UP | 29 | 9 | 17758 | 1761 |
BCAR3,DDX58,MMP15,CYR61,RND3,NR4A1,PLK2,TSC22D3,IFIT1 |
| 1.446e-03 | -6.54 | Pkinase_C | interpro domains | IPR017892 | 29 | 9 | 18293 | 1814 |
RPS6KA2,AKT1,STK38,RPS6KA1,CIT,SGK3,SGK1,PRKCQ,PKN1 |
| 1.446e-03 | -6.54 | Ets_dom | interpro domains | IPR000418 | 29 | 9 | 18293 | 1814 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7,ELF3 |
| 1.450e-03 | -6.54 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | 194 | 33 | 17758 | 1761 |
PLA2G4A,HEBP1,TSC22D3,EPS8,CYB561,FAM101B,IL18R1,SIRPA,TMEM63A,IER3,CCND1,CA2,RGS3,MITF,PCYOX1,TMEM51,FAM102A,DAB2IP,HLA-C,IGDCC4,SULF2,SOCS5,USP18,GCLC,NR1D2,HOXA9,PRCP,CDCA7L,ARRB1,LRRK1,GEM,ABCA1,CD33 |
| 1.450e-03 | -6.54 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN | 194 | 33 | 17758 | 1761 |
CASP3,CKAP2,SLC25A13,ITGA6,PDIA5,ABCG2,MORC4,NCKAP1,CA8,ERP29,FBLN1,BARD1,BEX2,EPDR1,FAM111A,ARVCF,GOT1,BUB1,F2R,SYTL3,CCDC88A,PGM1,CENPA,MRPS33,GCLC,EZR,PRKCQ,ANLN,AMZ2,PTPRF,RAP2C,AURKA,AHR |
| 1.450e-03 | -6.54 | GSE3982_BASOPHIL_VS_TH1_DN | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_DN | 194 | 33 | 17758 | 1761 |
CCNE2,MRC2,PPP1R2,NQO1,MRPS15,CAST,PDIA5,SYTL2,SAC3D1,RANBP1,NEK2,AKR1B1,TUBG1,GLB1L2,DIXDC1,PDE4D,APOBEC3G,MYO5A,CKS2,PPIF,DOCK4,TESK1,SNTB2,MICB,GGH,ADRBK2,PLEKHG6,DDOST,NETO2,AURKA,STK39,HMGA1,NRBP1 |
| 1.454e-03 | -6.53 | macromolecule glycosylation | biological process | GO:0043413 | 344 | 53 | 16441 | 1675 |
CMAS,GALNT12,GNE,PDIA3,CTSZ,NANS,MGAT5B,B4GALT4,POMGNT1,ADAMTSL4,B4GALNT1,B3GALNT1,MUC16,FUT2,MUC4,CTSC,A4GALT,ALG13,MGAT4A,FUT8,FUT1,UBE2J1,RPN2,LMAN1,TIPARP,MGAT5,PPP6R1,GCNT1,TRAK2,GFPT1,SIRT1,B3GALT6,SEC23A,B3GNT7,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,GALNT7,MCFD2,ARF4,GALNT3,FUCA1,MAN2A2,UAP1,SERPINA1,DDOST,DOLPP1,GNPTAB,CTSA,ST3GAL1 |
| 1.454e-03 | -6.53 | protein glycosylation | biological process | GO:0006486 | 344 | 53 | 16441 | 1675 |
CMAS,GALNT12,GNE,PDIA3,CTSZ,NANS,MGAT5B,POMGNT1,B4GALT4,ADAMTSL4,B4GALNT1,B3GALNT1,MUC16,FUT2,MUC4,CTSC,A4GALT,ALG13,MGAT4A,FUT8,UBE2J1,FUT1,RPN2,LMAN1,TIPARP,PPP6R1,MGAT5,GCNT1,TRAK2,B3GALT6,GFPT1,SIRT1,B3GNT7,SEC23A,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,GALNT7,MCFD2,ARF4,MAN2A2,FUCA1,GALNT3,UAP1,DDOST,SERPINA1,DOLPP1,GNPTAB,CTSA,ST3GAL1 |
| 1.464e-03 | -6.53 | DNPEP (aspartyl aminopeptidase) | protein interactions | 23549 | 27 | 9 | 16036 | 1726 |
TNS3,UGP2,PLOD2,MPP1,SAT1,KCTD12,ADAMTSL4,TBC1D4,MDFI |
| 1.474e-03 | -6.52 | SUN | prosite domains | PS51469 | 6 | 4 | 11866 | 1235 |
SUN1,SUN2,SUN3,SUCO |
| 1.476e-03 | -6.52 | IVANOVSKA_MIR106B_TARGETS | MSigDB lists | IVANOVSKA_MIR106B_TARGETS | 85 | 18 | 17758 | 1761 |
EIF5A2,FAM134A,PRRG4,FZD6,ZFYVE9,CCND1,BTG3,JAK1,ZNF367,LIMK1,ENPP5,NETO2,CLIP4,NCEH1,RASGEF1A,PKIA,CYBRD1,RGMA |
| 1.476e-03 | -6.52 | SAFFORD_T_LYMPHOCYTE_ANERGY | MSigDB lists | SAFFORD_T_LYMPHOCYTE_ANERGY | 85 | 18 | 17758 | 1761 |
MMD,FURIN,ISYNA1,DDR1,TNFRSF19,TNFSF9,CASP4,IER3,HLF,CSF1,S100A5,NR4A3,NR4A2,MYH14,MARCH2,F2R,JAK3,JARID2 |
| 1.476e-03 | -6.52 | NELSON_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | NELSON_RESPONSE_TO_ANDROGEN_UP | 85 | 18 | 17758 | 1761 |
CPD,NKX3-1,SAT1,SEPP1,MERTK,MYL12A,APPBP2,DNAJB9,UAP1,H1F0,DBI,ALDH1A3,INPP4B,SGK1,STK39,ITGAV,LMAN1,LIFR |
| 1.476e-03 | -6.52 | MODULE_138 | MSigDB lists | MODULE_138 | 85 | 18 | 17758 | 1761 |
MYL9,WASF3,COL9A3,IL15RA,FXYD3,CASP9,DHX8,KLK6,GDF15,PRKCQ,ETS1,ARHGAP35,ST5,BMP7,NRG1,DRP2,TOB1,MYO5A |
| 1.476e-03 | -6.52 | M_PHASE_OF_MITOTIC_CELL_CYCLE | MSigDB lists | M_PHASE_OF_MITOTIC_CELL_CYCLE | 85 | 18 | 17758 | 1761 |
PLK1,ZWINT,DLGAP5,CIT,NDC80,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDCA5,NEK2,AURKA,BUB1,CENPE,UBE2C,ESPL1,MPHOSPH9 |
| 1.479e-03 | -6.52 | HLA-DRA (major histocompatibility complex, class II, DR alpha) | protein interactions | 3122 | 43 | 12 | 16036 | 1726 |
MAN2A2,MBP,TCTN2,STIM1,CD63,CD82,IMPAD1,LRIG1,NETO2,EPHB4,ATP1B1,PLXNA1 |
| 1.484e-03 | -6.51 | negative regulation of cellular protein localization | biological process | GO:1903828 | 131 | 25 | 16441 | 1675 |
LZTFL1,TXN,ERLEC1,NFKBIE,THRA,LITAF,RAB23,PSMD10,BCL2L1,TP53INP2,BARD1,APC2,NOV,SP100,PPP2R5A,BMP7,CABP1,NFKBIA,UBE2J1,DAB2IP,MDFIC,YOD1,PKIA,MDFI,CHP1 |
| 1.486e-03 | -6.51 | sarcolemma | cellular component | GO:0042383 | 112 | 22 | 17570 | 1756 |
LAMP1,BIN1,SCN5A,SGCE,SLC2A4,COL6A2,UTRN,EZR,PRKCQ,ATP1B1,SNTB1,SLC8B1,DAG1,SNTA1,ATP1A1,SLC27A6,ITGA7,COL6A1,DLG1,CACNA1D,SCN2A,SGCB |
| 1.490e-03 | -6.51 | UEDA_PERIFERAL_CLOCK | MSigDB lists | UEDA_PERIFERAL_CLOCK | 164 | 29 | 17758 | 1761 |
LMO7,GCLC,GNE,HAL,LITAF,PPARA,SPATA13,COL18A1,HTATIP2,DNAJB11,SLC11A2,GLO1,DHRS3,ALCAM,POR,KIAA1161,PDIA4,GABARAPL1,MESDC2,ONECUT1,NR1D2,CD9,BRI3,TLE1,KLF9,ERBB3,F2R,ST3GAL1,CKS2 |
| 1.493e-03 | -6.51 | ZHU_CMV_ALL_UP | MSigDB lists | ZHU_CMV_ALL_UP | 120 | 23 | 17758 | 1761 |
PLA2G4A,MX1,REC8,CD55,B3GNT2,ENO2,NR4A1,HLA-E,TAP1,NUBP1,EMP2,SCARB2,SP100,NFKBIA,RANBP1,NR4A3,IRF2,TRIM21,IFIT1,PIM1,MANF,LGMN,IFI6 |
| 1.495e-03 | -6.51 | regulation of microtubule cytoskeleton organization | biological process | GO:0070507 | 124 | 24 | 16441 | 1675 |
PLK1,GAS2L1,CAMSAP3,RHOA,CKAP2,STMN3,CCNF,CCNB1,HDAC6,NUBP1,KIF11,APC2,BORA,CDK5R1,MID1IP1,PLK2,TBCD,NEK2,PLK4,AURKA,CDKN1B,EFNA5,DIXDC1,WNT3A |
| 1.500e-03 | -6.50 | Information processing speed(PMID:21130836) | GWAS genes | Information processing speed(PMID:21130836) | 9 | 5 | 2389 | 269 |
ATRNL1,KCTD2,MYRIP,TMEM245,FAM110C |
| 1.502e-03 | -6.50 | collagen metabolic process | biological process | GO:0032963 | 83 | 18 | 16441 | 1675 |
COL9A3,ADAMTS2,MRC2,COL6A2,P3H2,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,COL16A1 |
| 1.503e-03 | -6.50 | V$TFIIA_Q6 | MSigDB lists | V$TFIIA_Q6 | 241 | 39 | 17758 | 1761 |
ANXA3,HAPLN3,TSC22D3,NKRF,VASH1,LMNA,CCND1,TFAP4,FOXP2,ADD3,ITGA3,ANKS1B,LHX6,FOSB,BCL6,CDH3,RFX5,ARMCX6,BTBD3,CKAP4,FRS3,SSH3,NR4A1,ITCH,CBX6,HMG20B,EPHA1,PDIK1L,NFIB,NIN,MMP15,HOXA9,AXL,PELI2,KLK7,REEP4,COL16A1,ABCA1,GOLGB1 |
| 1.509e-03 | -6.50 | lipid localization | biological process | GO:0010876 | 258 | 42 | 16441 | 1675 |
PLA2G4A,PRKAA2,ACACB,CPT2,ATP9A,ATP8A1,HEXB,ANO9,B4GALNT1,SLC27A6,OSBPL3,KCNN4,FABP6,ABCA2,ATP8B1,SORL1,ABCD1,ACSL4,ANO4,GM2A,NCOA2,FZD4,ACVR1C,ANO6,PPARA,NPC2,ATP8B3,PCTP,CPTP,SPNS3,ATP10D,PLIN5,ENPP1,PRKAG2,TMEM30A,MFSD2A,SLC27A1,PITPNA,ABCA1,APOL2,ESYT2,ABCG1 |
| 1.512e-03 | -6.49 | ZHU_CMV_24_HR_UP | MSigDB lists | ZHU_CMV_24_HR_UP | 92 | 19 | 17758 | 1761 |
PLA2G4A,MX1,REC8,CD55,B3GNT2,ENO2,NR4A1,HLA-E,TAP1,EMP2,NUBP1,SCARB2,NFKBIA,RANBP1,TRIM21,IFIT1,PIM1,MANF,IFI6 |
| 1.516e-03 | -6.49 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | 113 | 22 | 17758 | 1761 |
LASP1,IFITM3,NR4A1,DAP,SDC4,TRIB2,HLA-A,MECOM,SOCS3,GALNT3,AGPAT2,GNB5,GPRC5B,KCNK1,RGS3,SETD3,FOSB,TSPAN18,ELF5,DAPK1,TNFRSF12A,ECE1 |
| 1.516e-03 | -6.49 | ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | ACTIN_FILAMENT_BASED_PROCESS | 113 | 22 | 17758 | 1761 |
WASF3,PACSIN2,SORBS1,RHOA,NF2,SSH1,EZR,TESK2,ARHGDIB,MRAS,BCAR1,RASA1,ARHGEF10L,RND3,LIMK1,DLG1,PRKG1,FGD6,ARF6,SHROOM2,CCDC88A,FGD1 |
| 1.520e-03 | -6.49 | Signaling Pathways in Glioblastoma | WikiPathways | WP2261 | 80 | 19 | 4455 | 516 |
AKT1,PIK3R1,TP53,ERBB2,PRKCQ,CDKN2C,CCND1,PLCG1,IGF1R,PTEN,FGFR2,PLCG2,PIK3CA,CDKN1B,PIK3C2B,PIK3CD,ERBB3,GAB1,SPRY2 |
| 1.522e-03 | -6.49 | negative regulation of growth | biological process | GO:0045926 | 235 | 39 | 16441 | 1675 |
GAS2L1,SEMA6B,NF2,SERPINE2,TP53,CDKN2C,NOV,PTEN,BCL6,ADAM15,CDKN1B,MAPK11,SEMA3G,WNT3A,LGMN,CDKN2D,OSGIN1,SEMA3B,SIRT1,SMARCA2,ING1,SERTAD3,CDA,SAV1,BBS2,CDK5R1,GNAS,JADE1,ENPP1,PTPRJ,SEMA4D,ACVRL1,CGREF1,NKD1,SH3BP4,NOD2,ADIPOR1,FHL1,SEMA3A |
| 1.528e-03 | -6.48 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 678 | 91 | 17775 | 1757 |
MTM1,PPP4R4,GRHL2,LGR4,PAPSS2,ARFGEF1,TP53,VARS2,CAMK1D,ITPR2,SLC7A2,TMC1,DENND2D,CYP39A1,ZNF385B,SLC9A7,SH3KBP1,GRM5,DAPK2,MUC16,SP100,PAPSS1,ANKFN1,MITF,PIK3CA,DAB2IP,PDE4D,SCN2A,ZNF365,MCTP1,UTRN,CDCA2,PRKCQ,KIF13A,LDB2,PPP1R14C,IDH1,ALCAM,DOCK5,NOD2,NRG1,GLA,GLCCI1,COBL,DENND5B,DDX58,RUNX2,LRRFIP2,TBC1D1,ATP9A,ITGA6,ABCG2,GABRG2,SELL,PBX3,SLC36A4,INTS8,CNTNAP2,DNAH3,ANO1,ZDHHC21,CD109,CA2,ITGB8,PIK3AP1,ARSG,FAM189A1,CTSC,MAP3K9,KIAA0319,PRKG1,CACNA1D,MYO5A,CHSY3,RGMB,MRS2,SYBU,MAML2,ANTXR1,BSDC1,KLHL2,FECH,PLEKHH2,PRKAG2,SYT7,TBX18,AMMECR1,ALPK3,GRAMD1C,SEMA3A,DOCK9 |
| 1.529e-03 | -6.48 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 99 | 20 | 17758 | 1761 |
GFPT1,CASP3,GAA,SORT1,TIMP2,PPP1R2,NR4A1,F12,YES1,DNAJB9,PDIA4,APOBEC3B,DNAJC10,UAP1,ZFP36,UBE2J1,AHCY,FHL1,HSPB1,TRAM1 |
| 1.529e-03 | -6.48 | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | MSigDB lists | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | 99 | 20 | 17758 | 1761 |
TSC22D3,PIK3R1,ZFAND5,IRS2,SLCO4A1,TIMP3,CTGF,CYR61,METTL7A,KCNK1,RND3,CALD1,ZFP36,NFKBIA,BCL6,DIXDC1,KLF9,FHL1,TIPARP,DOCK9 |
| 1.530e-03 | -6.48 | HALLMARK_UV_RESPONSE_DN | MSigDB lists | HALLMARK_UV_RESPONSE_DN | 142 | 26 | 17758 | 1761 |
LTBP1,FBLN5,NR3C1,RASA2,ERBB2,PRKAR2B,NFIB,PIAS3,ADD3,IGF1R,PTEN,CYR61,NR1D2,RND3,SIPA1L1,DLG1,INPP4B,CDKN1B,SFMBT1,PIK3CD,CITED2,ZMIZ1,ARHGEF9,ATP2B1,ABCC1,GCNT1 |
| 1.530e-03 | -6.48 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 142 | 26 | 17758 | 1761 |
GCLM,CD55,ARMCX3,CDKN1C,IL15,DNAJB2,SAT1,NFE2L1,FTH1,FNDC3A,ZFAND5,PHLDA1,TNFSF9,STEAP1,STX3,BSDC1,DNAJB9,GABARAPL1,RND3,P4HA2,ZNF165,GLA,HSPB1,DGKG,MAFF,NCOA2 |
| 1.531e-03 | -6.48 | response to organonitrogen compound | biological process | GO:0010243 | 907 | 120 | 16441 | 1675 |
CASP3,SPRED1,SORBS1,SLC2A4,SSH1,FOXM1,PSME2,NRG2,ERBB2,PSME1,ITPR2,BCL2L1,PRKACA,PDGFB,SDC1,SPTB,CALM2,CCND1,PDGFA,ATP6V0B,SESN3,PSMD1,CDH1,CTGF,SHC3,DPYSL2,KLF3,FOSB,SRR,PIK3CA,AKR1B1,CDKN1B,DAB2IP,GOT1,PDE4D,RASGEF1A,RASGRP1,FRS3,SIRT1,RIPK2,AKT1,ACVR1C,EZR,PRKAR2B,PRKCQ,ERBB2IP,POR,CASP4,DAG1,RHEB,SOCS3,IRS2,ENPP1,DUOX1,IDE,JAK1,NOD2,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,GAB1,RRAGD,PRKAA2,SORT1,CPEB4,RASA2,DGKQ,SOX9,CALM3,GABRG2,PSMD10,SELL,FGF19,HDAC9,IGF1R,PTEN,BMP7,COL6A1,BAX,TMBIM6,ERBB3,NCAM1,MYO5A,GCNT1,PDGFC,RASGRF1,RHOA,SHMT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,FOS,BCAR1,PSMA4,RASA1,GPLD1,GNAS,TIMP3,PRKAG2,FGFR2,NFKBIA,SH3BP4,NR4A3,GRIN2D,NR4A2,GPER1,JAK3,TBC1D4,CPEB2,COL16A1 |
| 1.535e-03 | -6.48 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | 187 | 32 | 17758 | 1761 |
BIN1,CCNI,TRIP10,PPM1J,TMEM55B,CENPN,UBE2Q2,RNF220,KIAA1107,PAPSS1,ESPN,AHCY,RPN2,CRTAP,KDELR1,CYP1B1,GCNT1,SUSD3,SYPL1,ARHGDIB,FNDC3A,PPP1R14C,FANCE,GNA11,SOCS3,AHRR,XKRX,ACVRL1,ITGA7,GLA,REEP4,DEF6 |
| 1.535e-03 | -6.48 | ETS_DOMAIN_3 | prosite domains | PS50061 | 28 | 9 | 11866 | 1235 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7,ELF3 |
| 1.540e-03 | -6.48 | cerebellum | COSMIC cancer mutations | cerebellum | 801 | 105 | 17775 | 1757 |
MTM1,PPP4R4,NF2,GRHL2,LGR4,PAPSS2,RET,ARFGEF1,TP53,VARS2,CAMK1D,ITPR2,SLC7A2,TMC1,DENND2D,CYP39A1,ZNF385B,SLC9A7,SH3KBP1,GRM5,CDS1,DAPK2,MUC16,SP100,PAPSS1,ANKFN1,MITF,PIK3CA,DAB2IP,PDE4D,ANO4,SCN2A,ZNF365,MCTP1,AKT1,UTRN,CDCA2,PRKCQ,KIF13A,LDB2,PPP1R14C,ASB13,IDH1,ALCAM,DOCK5,ATP10D,NOD2,NRG1,GLA,GLCCI1,COBL,DENND5B,DDX58,RUNX2,LRRFIP2,KLHL13,TBC1D1,ATP9A,ITGA6,ABCG2,GABRG2,SELL,PBX3,SLC36A4,CNTNAP2,INTS8,DNAH3,ANO1,ZDHHC21,CD109,CA2,ITGB8,PIK3AP1,PTEN,ARSG,FAM189A1,CTSC,MAP3K9,KIAA0319,PRKG1,CACNA1D,MYO5A,CHSY3,TGIF1,FADS2,RGMB,MRS2,SYBU,MAML2,ANTXR1,BSDC1,GNAS,KLHL2,FECH,HLA-B,PLEKHH2,PRKAG2,SYT7,TBX18,AMMECR1,PPM1H,ALPK3,GRAMD1C,SEMA3A,DOCK9 |
| 1.541e-03 | -6.48 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3665 | 411 | 17775 | 1757 |
GAA,HSPG2,HEXB,RET,DHX8,FAM102B,PSME1,CCNB1,PJA2,CA8,BARD1,FAM101B,SLC9A7,GRM5,OSBPL3,STEAP2,PIK3CA,CLDN4,IQCD,RNF26,TIAM1,ERAP2,METAP2,TNIP1,SPATA18,MTRF1L,KIF13A,TNS1,PIF1,RNF19B,COL12A1,AHRR,SLC25A4,PLK2,ATP7B,LRIG1,NOD2,EIF4EBP2,SERPINI1,TANC2,ARF6,F2RL1,CDK17,FRMD4A,TBC1D1,ITGA6,SOX9,C6orf106,KIF23,PSIP1,MECOM,C9orf69,MARCH8,DOPEY2,FRY,ITGA3,PIK3AP1,BHLHE41,MEGF8,FAM13B,BDH1,DAPK1,PRKG1,PCYOX1,SORL1,CADPS2,ALPK1,CACNA1D,MYLIP,DGKG,RIMS2,PMPCB,KIF20A,ANO6,NPHP3,RASA1,STK17A,MMP15,PTPRF,NCOA3,TJP3,SLC4A4,ISM1,SETD3,ITPR1,SLC4A3,AGBL5,CLMN,PCDH19,DRP2,MAP3K5,IFIH1,ZNF502,TMEM173,RUSC1,XDH,DOCK9,PLA2G4A,FRMPD3,SLC2A4,TCTN2,REPS2,TRIP10,NLRX1,IQGAP1,RALBP1,ATP2C2,RGS20,PKP2,RNF182,KCTD12,GRK6,APC2,TNFSF9,ZNF385B,MUC16,ACAP2,DACT1,ENPP5,DAB2IP,IFIT1,LGMN,ZNF365,NAGA,SCN3A,GPX4,MYO5B,DOCK4,RIPK2,SEPT6,SYNE2,PANK1,UTRN,KIF1C,CDCA2,NUSAP1,PKMYT1,C15orf39,ITPR3,ALCAM,ATP10D,CMTM7,AMZ2,SHROOM3,SLC9A6,ZNF704,PLEKHG1,PNPLA6,SLC27A1,NRG1,HS3ST3B1,SLC27A3,DENND5B,TTC8,TNRC6C,NKX3-1,PCOLCE,CKAP2,HAPLN3,OSGIN2,PDIA3,PKN1,ETS1,DNAH3,SIX4,WWP2,SCML1,AKIRIN1,ADD3,FUT2,SLC27A6,PTEN,FUT8,ATP8B1,ADAM15,TMBIM6,WWP1,ERBB3,SGCB,SPRY2,TPCN1,MED22,PVRL4,RASGRF1,TGIF1,ZWINT,ARHGEF28,LCA5,ERMAP,FAM160A1,RAPGEF2,PIK3R1,NUB1,GRIN1,ZKSCAN2,AK4,CRISPLD2,GALNT3,MAMDC4,SYT7,ACVRL1,TBX18,ABCB1,CENPE,NCAPG2,ACOT7,TLL2,ESYT2,RGMA,TRIM2,UGT8,EPAS1,ARFGEF1,NDC80,DNAJB11,TEX2,VARS2,DNER,CACNB4,KREMEN1,TMC1,SPTB,FANCI,PTCHD4,PLS3,SUSD2,ARHGEF10L,CPNE2,LRRC6,ZCCHC12,IL6ST,ANKFN1,ABCA2,DUSP10,ANKRD12,TLN2,PTPRE,BTBD3,NEB,SMAGP,LAMP3,ZNF462,THRB,CELSR2,RGAG1,ARHGDIB,ZBTB7B,PTGFRN,DZIP1L,LRRC42,HS6ST1,MFAP3L,PLEKHG6,MSL1,ARHGEF19,NEIL1,MAP2,RAB11FIP1,PIEZO1,GLCCI1,PCSK5,PRKAA2,ARAP3,PARP12,UBASH3B,ETV5,ABCG2,CALM3,ADCK5,NCKAP1,CNTNAP2,PHLPP1,ADAMTSL4,ZNF432,TNS3,CA2,FRAS1,KIF13B,COL6A1,EXOC8,RFX5,PIM1,SLC12A2,PLCB2,SNX7,MDFI,ABCC1,DPYSL5,PLEKHA6,BTNL9,GYLTL1B,PDE5A,STRADB,NUBP1,G2E3,MUM1L1,PRX,SOX13,GNAS,XKRX,SLC6A6,COQ10A,CSF1,MFSD2A,PHLPP2,CGREF1,SLC2A6,ALPK3,JAK3,SEMA3A,COL16A1,RARG,PROM2,NCKAP5,XYLT1,TP53,TDRKH,SLC7A2,PHLDA1,ARHGEF16,SYTL2,TTC21B,SS18,WDR44,REEP1,PLCG2,SRR,EPB41L4B,NOTCH3,ECE1,OAS3,PDIA6,GM2A,CPD,SIRT1,TMTC1,PTGER4,DOCK5,ARHGAP35,IDE,RBL1,BHLHB9,ADAMTS14,OVOL1,PTBP3,SPTBN5,CYP2U1,ABCA1,LIFR,CDH22,ARHGEF11,RUSC2,FRMD6,GABRG2,MIER3,TGFBR1,NKRF,COL4A5,SBF1,DSE,VPS26A,HMGXB4,SLC9A2,SIRPA,HDAC9,SAC3D1,TOP2A,IRF2BPL,MDM1,LLGL2,RRBP1,TSPAN13,CLIP2,ATP2B1,GCNT1,DLGAP1,PGM1,SUN2,AMFR,ASPM,RC3H2,PPARA,LRRC66,PRICKLE1,COL7A1,PELI3,TXNDC11,LEPR,BSDC1,FUCA1,ARHGAP24,FAT4,SCG2,NMI,TMC5,NETO2,CLIP4,ARRB1,PPP2R3C,SH3BGRL2,GRAMD1C,HOXB13,SOX8,ICOSLG,TBC1D4,HIPK3,ARHGEF9,RAB3IL1,ARHGEF4,DIS3L,GOLGB1 |
| 1.543e-03 | -6.47 | ruffle membrane | cellular component | GO:0032587 | 78 | 17 | 17570 | 1756 |
DDX58,EPB41L5,PACSIN2,RHOA,NF2,EPS8,SPATA13,EZR,AIF1L,EPS8L2,ARF4,RASGRP2,PTPRJ,ITGAV,PACSIN1,SPRY2,ARHGEF4 |
| 1.545e-03 | -6.47 | bone-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chondrosarcoma-dedifferentiated | 10 | 5 | 17775 | 1757 |
GNAS,SS18,IDH1,PIK3CA,TP53 |
| 1.545e-03 | -6.47 | membrane raft | cellular component | GO:0045121 | 271 | 43 | 17570 | 1756 |
CASP3,SPRED1,SCN5A,SORBS1,SLC2A4,PACSIN2,NF2,RET,SDC4,LRP4,EFHD2,ERBB2,HDAC6,PRKACA,EMP2,EFNB1,CDH1,IGF1R,KCNN4,DLG1,TRPC1,PIKFYVE,F2R,CD55,PLSCR1,RGMB,FURIN,EZR,PRKAR2B,ATP1B1,DAG1,FAS,ATP1A1,HPSE,CORO1C,PRKCDBP,SLC27A1,EFNA5,ATP1B3,MAL2,UNC5B,ABCA1,PROM2 |
| 1.548e-03 | -6.47 | HUPER_BREAST_BASAL_VS_LUMINAL_DN | MSigDB lists | HUPER_BREAST_BASAL_VS_LUMINAL_DN | 59 | 14 | 17758 | 1761 |
FUCA1,HLA-B,ENO2,MLPH,CYR61,HLA-F,VWA1,CLDN4,KLK6,HMGA1,HLA-C,GAD1,ALCAM,SEMA3B |
| 1.548e-03 | -6.47 | GNF2_RFC4 | MSigDB lists | GNF2_RFC4 | 59 | 14 | 17758 | 1761 |
TOP2A,ZWINT,FOXM1,ASPM,RANBP1,NDC80,PLK4,CCNB2,KIF11,UBE2C,CDK1,FANCI,CKS2,PRIM1 |
| 1.557e-03 | -6.46 | peptidyl-tyrosine phosphorylation | biological process | GO:0018108 | 153 | 28 | 16441 | 1675 |
RIPK2,TESK1,IL15,EPHA4,RET,TESK2,ERBB2,EPHA1,ROR1,TEC,YES1,PDGFB,DDR1,MERTK,EPHA10,WEE1,JAK1,IGF1R,FGFR2,AXL,PTK7,RYK,MAP3K9,EPHB4,F2R,JAK3,SYK,MELK |
| 1.560e-03 | -6.46 | regulation of mitotic cell cycle | biological process | GO:0007346 | 475 | 69 | 16441 | 1675 |
HECA,DLGAP5,PSME2,CUL4B,CTDSPL,PTTG1,TP53,PSME1,BCL2L1,CCNB1,PDGFB,FANCI,IER3,CCND1,BTG3,CYP1A1,PSMD1,DACT1,KIF14,DLG1,CDKN1B,CTDSP2,PLK1,SIRT1,TIMP2,AKT1,CDC20,PRKCQ,NUSAP1,RAD17,PKMYT1,ANLN,CDK1,MAP3K6,JADE1,STK26,PLK2,OVOL1,NKX3-1,CDKN1C,CIT,PSMD10,TOP2A,E2F7,IGF1R,PTEN,BMP7,NEK2,BUB1,PIM1,HES1,ZWINT,PSMB4,RGCC,STRADB,SCRIB,BORA,KIF11,PSMA4,TJP3,FGFR2,CDCA5,AURKA,STK39,FHL1,CENPE,UBE2C,ESPL1,PKIA |
| 1.560e-03 | -6.46 | LINDVALL_IMMORTALIZED_BY_TERT_UP | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_UP | 72 | 16 | 17758 | 1761 |
TMTC1,FRMD4A,PAPSS2,PDE5A,CTSZ,FZD7,TAPBP,ST5,CALD1,TRIOBP,CD9,MDFIC,FHL1,HMGA1,CITED2,ATP2B1 |
| 1.560e-03 | -6.46 | KEGG_ADHERENS_JUNCTION | MSigDB lists | KEGG_ADHERENS_JUNCTION | 72 | 16 | 17758 | 1761 |
LMO7,PVRL4,WASF3,SORBS1,RHOA,IQGAP1,ERBB2,TCF7,TGFBR1,YES1,PTPRF,PTPRJ,CDH1,IGF1R,PVRL2,FARP2 |
| 1.561e-03 | -6.46 | CREB phosphorylation through the activation of CaMKK | REACTOME pathways | R-HSA-442717 | 6 | 4 | 8202 | 867 |
CALM3,CALM2,CAMKK1,CALM1 |
| 1.561e-03 | -6.46 | Phosphorylation of Emi1 | REACTOME pathways | R-HSA-176417 | 6 | 4 | 8202 | 867 |
PLK1,CCNB1,CDK1,CDC20 |
| 1.567e-03 | -6.46 | Interferon alpha/beta signaling | REACTOME pathways | R-HSA-909733 | 68 | 16 | 8202 | 867 |
MX1,IFITM3,HLA-E,HLA-F,USP18,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,IRF2,IRF7,HLA-C,OAS3,IFIT1,IFI6 |
| 1.567e-03 | -6.46 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | MSigDB lists | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | 10 | 5 | 17758 | 1761 |
DAPK2,CASP3,UNC5B,CASP9,DAPK1 |
| 1.576e-03 | -6.45 | plasma membrane organization | biological process | GO:0007009 | 205 | 35 | 16441 | 1675 |
PACSIN2,TSPAN15,PKP2,MPP5,F11R,ANO9,EMP2,SPTB,RAB15,CDH1,PTEN,A4GALT,DLG1,ZDHHC23,PLEKHF1,ANO4,PACSIN1,MYO5A,XKR8,RAB3B,KCNIP3,AKT1,PLSCR1,CRB3,RAPGEF2,ANO6,EZR,KIF13A,ARFRP1,ATP1B1,BBS2,OPTN,FAT4,SYT7,ATP1B3 |
| 1.576e-03 | -6.45 | columnar_cell_lesion | COSMIC cancer mutations | columnar_cell_lesion | 35 | 10 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 1.576e-03 | -6.45 | breast-hyperplasia-columnar_cell_lesion | COSMIC cancer mutations | breast-hyperplasia-columnar_cell_lesion | 35 | 10 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 1.577e-03 | -6.45 | TMFOUR | prints domains | PR00259 | 30 | 9 | 4759 | 462 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,TSPAN7 |
| 1.578e-03 | -6.45 | mesenchyme development | biological process | GO:0060485 | 190 | 33 | 16441 | 1675 |
SEMA6B,RET,SOX9,TGFBR1,NCKAP1,FAM101B,FGF19,EFNB1,SIX4,BMP7,ADAM15,TWIST1,ERBB3,SEMA3G,WNT3A,CITED2,SEMA3B,EPB41L5,HES1,S100A4,AMER1,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,PTK7,FAM83D,NRG1,SOX8,OSR1,SEMA3A |
| 1.581e-03 | -6.45 | YANG_BREAST_CANCER_ESR1_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_DN | 24 | 8 | 17758 | 1761 |
PLCH1,BTG3,TRIM2,SLC9A6,CYB5R2,CDH3,LBR,ARHGEF9 |
| 1.581e-03 | -6.45 | PROTEIN_KINASE_INHIBITOR_ACTIVITY | MSigDB lists | PROTEIN_KINASE_INHIBITOR_ACTIVITY | 24 | 8 | 17758 | 1761 |
CDKN2C,CDKN1C,DNAJC3,CDKN1B,CDKN2D,PKIA,MAPK8IP1,SOCS3 |
| 1.581e-03 | -6.45 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | MSigDB lists | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | 24 | 8 | 17758 | 1761 |
MYL9,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B |
| 1.581e-03 | -6.45 | BIOCARTA_G2_PATHWAY | MSigDB lists | BIOCARTA_G2_PATHWAY | 24 | 8 | 17758 | 1761 |
PLK1,WEE1,RPS6KA1,TP53,CCNB1,MYT1,CDKN2D,CDK1 |
| 1.581e-03 | -6.45 | MHC_I-like_Ag-recog | interpro domains | IPR011161 | 24 | 8 | 18293 | 1814 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 1.583e-03 | -6.45 | GSE17721_CTRL_VS_LPS_4H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_4H_BMDM_DN | 195 | 33 | 17758 | 1761 |
WASF3,LZTFL1,GRHL2,TSPAN15,FRMD6,IQGAP1,IL18,BCL2L1,CA8,IER3,LMO4,SLC44A1,CD70,WNT3A,TMEM9,SMAGP,GCA,ZC3H11A,NR4A1,SLC39A8,KLK6,PSMA4,ARHGAP35,CARHSP1,RBM47,FAAH,PVRL2,PRKCDBP,ARF6,TRAF5,E2F8,HOXC13,JARID2 |
| 1.583e-03 | -6.45 | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | MSigDB lists | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | 135 | 25 | 17758 | 1761 |
NUDT6,PDGFC,PRSS23,EPAS1,EPHA4,ERBB2,EPHA1,NRP2,FZD7,EPHA10,MDK,TYMP,TIMP3,CTGF,PTEN,FGFR2,TNFRSF12A,EFNA5,DIXDC1,EPHB4,NOTCH3,FZD5,F2RL1,DVL2,FRS3 |
| 1.589e-03 | -6.44 | MODULE_55 | MSigDB lists | MODULE_55 | 808 | 106 | 17758 | 1761 |
MYL9,BCAM,NQO1,HSPG2,EPAS1,S100A11,CRYM,THRA,PTTG1,NRG2,COL18A1,SDC1,APC2,PHLDA1,CARD10,IER3,CCND1,DAPK2,EPCAM,SCNN1A,CDH1,ALDH1A3,TACSTD2,GOT1,IFIT1,ACOX2,LGMN,SMAGP,CKS2,SGCE,CD55,COL6A2,S100A4,CDC20,CDA,F12,ICMT,CCNF,ENPP1,BMP1,NRGN,ABCA1,GRN,PRSS8,GCLM,PINK1,PCOLCE,ATP9A,DNAJB2,ITGA6,DCAF7,BLVRB,SOX9,GNE,GDF15,SEPP1,DHRS3,DNAH3,HOXB2,TSPAN7,CA2,ITGA3,CYR61,LLGL2,LYPD3,GATA2,KCNN4,BDH1,TBCD,COL6A1,GALNS,TFAP2A,ALDH7A1,IGFBP2,ERBB3,CITED2,PLCB2,ALDH3A2,RIMS2,FADS2,SHMT1,NR4A1,GCLC,FURIN,AK4,TCF7,COL7A1,FOS,CDK5R1,CYB5A,TIMP3,SERPINA1,SLC4A4,ETS2,PVRL2,FAAH,DHRS2,DTX4,SLC4A3,CDK18,JAK3,UBE2C,L1CAM,OCLN,XDH,CD33 |
| 1.598e-03 | -6.44 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 679 | 91 | 17775 | 1757 |
MTM1,PPP4R4,GRHL2,LGR4,PAPSS2,ARFGEF1,TP53,VARS2,CAMK1D,ITPR2,SLC7A2,TMC1,DENND2D,CYP39A1,ZNF385B,SLC9A7,SH3KBP1,GRM5,DAPK2,MUC16,SP100,PAPSS1,ANKFN1,MITF,PIK3CA,DAB2IP,PDE4D,SCN2A,ZNF365,MCTP1,UTRN,CDCA2,PRKCQ,KIF13A,LDB2,PPP1R14C,IDH1,ALCAM,DOCK5,NOD2,NRG1,GLA,GLCCI1,COBL,DENND5B,DDX58,RUNX2,LRRFIP2,TBC1D1,ATP9A,ITGA6,ABCG2,GABRG2,SELL,PBX3,SLC36A4,INTS8,CNTNAP2,DNAH3,ANO1,ZDHHC21,CD109,CA2,ITGB8,PIK3AP1,ARSG,FAM189A1,CTSC,MAP3K9,KIAA0319,PRKG1,CACNA1D,MYO5A,CHSY3,RGMB,MRS2,SYBU,MAML2,ANTXR1,BSDC1,KLHL2,FECH,PLEKHH2,PRKAG2,SYT7,TBX18,AMMECR1,ALPK3,GRAMD1C,SEMA3A,DOCK9 |
| 1.604e-03 | -6.44 | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | 19 | 7 | 17758 | 1761 |
UACA,ANLN,GRHL2,OAT,VANGL1,CMTM6,PHTF1 |
| 1.604e-03 | -6.44 | REGULATION_OF_JNK_ACTIVITY | MSigDB lists | REGULATION_OF_JNK_ACTIVITY | 19 | 7 | 17758 | 1761 |
MDFIC,MAP3K5,PKN1,MAP3K6,HIPK3,MDFI,MAP3K9 |
| 1.604e-03 | -6.44 | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN | MSigDB lists | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN | 19 | 7 | 17758 | 1761 |
HES1,PAPSS2,MYBL1,SGCB,ATP9A,MPHOSPH9,SAC3D1 |
| 1.604e-03 | -6.44 | VISALA_AGING_LYMPHOCYTE_DN | MSigDB lists | VISALA_AGING_LYMPHOCYTE_DN | 19 | 7 | 17758 | 1761 |
NRG2,COL9A3,RUNX3,CDK18,LGALS3,STAT4,SDC4 |
| 1.604e-03 | -6.44 | Ald_DH_N | interpro domains | IPR016162 | 19 | 7 | 18293 | 1814 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.604e-03 | -6.44 | Aldehyde_DH_dom | interpro domains | IPR015590 | 19 | 7 | 18293 | 1814 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.604e-03 | -6.44 | Ald_DH/histidinol_DH | interpro domains | IPR016161 | 19 | 7 | 18293 | 1814 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.604e-03 | -6.44 | Ald_DH_C | interpro domains | IPR016163 | 19 | 7 | 18293 | 1814 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.610e-03 | -6.43 | PTPRK (protein tyrosine phosphatase, receptor type, K) | protein interactions | 5796 | 92 | 20 | 16036 | 1726 |
COL6A2,TCTN2,LGALS3,CACNA2D2,PLXNA1,FBLN1,ARSK,DNAJB9,MAN2A2,CD109,SCARB2,ARSG,FRAS1,MEGF8,LRIG1,COL6A1,GALNS,ECE1,ARSB,PCSK5 |
| 1.615e-03 | -6.43 | ST_G_ALPHA_I_PATHWAY | MSigDB lists | ST_G_ALPHA_I_PATHWAY | 35 | 10 | 17758 | 1761 |
PITX2,AKT1,ITPR1,RGS20,ASAH1,ITPR2,ITPKA,ITPR3,PLCB2,DAG1 |
| 1.615e-03 | -6.43 | ISOMERASE_ACTIVITY | MSigDB lists | ISOMERASE_ACTIVITY | 35 | 10 | 17758 | 1761 |
TOP2A,PGM1,GNPDA1,GNE,PDIA5,PDIA3,DSE,PDIA6,ERP29,GLCE |
| 1.616e-03 | -6.43 | ATPase_P-typ_cyto_domN | interpro domains | IPR023299 | 35 | 10 | 18293 | 1814 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.617e-03 | -6.43 | PROTEIN_METABOLIC_PROCESS | MSigDB lists | PROTEIN_METABOLIC_PROCESS | 1211 | 151 | 17758 | 1761 |
CASP3,SIGIRR,SSH1,AASS,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,DAPK2,IL31RA,FUT1,DUSP10,RP2,TLN2,PTPRE,METAP2,TNIP1,CDA,LOXL2,GALNT7,ICMT,ANLN,STK17B,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,NOD2,BMP1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,PEX6,DNAJB2,MERTK,TSPAN7,RABGGTA,ATG4A,B3GALNT1,IGF1R,PAIP2B,RPL39,TBCD,TPST1,DAPK1,MAP3K9,PRKG1,PIM1,MYLIP,GAD1,CCDC88A,DDB2,MGAT4B,STRADB,EIF2AK1,NUBP1,RANBP9,RASA1,GLCE,STK17A,FAS,MAPKAPK2,MMP15,AURKA,JAK3,NF2,REPS2,ST14,HDAC11,PDIA5,TP53,TESK2,ERBB2,APC2,ZFYVE9,CCND1,PLK4,RPN2,PHKA2,LMAN1,PDIA6,F2R,ATG4D,SEPHS1,SIRT1,MAP3K3,AKT1,COG2,PTPRU,PTPN9,CDC20,DUSP4,CD40,MAP3K6,CASP4,DAG1,TAPBP,PTPRJ,IDE,ALDH5A1,STK38,NRG1,HS3ST3B1,MAPK12,WASF3,PINK1,TGFBR1,CTSZ,FBXO6,POMGNT1,PKN1,SBF1,TRIB2,AIP,PPP2R3A,WWP2,FUT2,PTEN,CDK16,MGAT4A,RRBP1,FUT8,CD9,BAX,SGK3,SGK1,WWP1,ERBB3,SYK,GCNT1,AMFR,PARP4,FURIN,UBE2A,YES1,PRDX4,ACVRL1,PLOD2,NR4A3,ERAP1,HMGA1,PLOD3,UBE2C,HIPK3,OCLN,ABCG1 |
| 1.622e-03 | -6.42 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | 180 | 31 | 17758 | 1761 |
DDX58,PCGF5,ARAP2,CCDC109B,PLSCR1,IL15RA,RIPK2,ARHGEF11,USP18,TAP1,HERC5,SAMD9,CD274,IFIT3,HERC6,TMCC3,FAS,DTX3L,OTUD1,FAM46A,C19orf66,SECTM1,NLRC5,IRF2,IFIT1,TINAGL1,OAS3,CMPK2,IFIH1,ETV7,APOBEC3G |
| 1.622e-03 | -6.42 | YYCATTCAWW_UNKNOWN | MSigDB lists | YYCATTCAWW_UNKNOWN | 180 | 31 | 17758 | 1761 |
LGALS3,NF2,HOXB7,GCLC,ETV5,PRKAR2B,DUSP4,TRIB2,SP4,NCS1,ZDHHC21,CCND1,AIM1L,IGF1R,KLF12,ETS2,CYR61,SCG2,DNM1L,RGS3,MFSD2A,BMP7,RANBP1,FOSB,NR4A3,TSPAN13,ETV4,PLCB2,TOB1,MAFF,SCN3A |
| 1.622e-03 | -6.42 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | 180 | 31 | 17758 | 1761 |
RASGRF1,MRC2,ENO2,TSPAN15,BCL9,STAT4,ITGA6,TMEM144,PRKCQ,DUSP4,DPP8,PHLDA1,HOXB2,ANO1,EDNRA,FRMD4B,NOV,HLF,FRY,SEMA4D,CGREF1,AMMECR1,INPP4B,SORL1,ATRNL1,PLEKHF1,PIM1,DLG3,RUSC1,RRAGD,CYP1B1 |
| 1.623e-03 | -6.42 | extracellular matrix component | cellular component | GO:0044420 | 127 | 24 | 17570 | 1756 |
LTBP1,TIMP2,FBLN5,HSPG2,ITGA6,P3H2,COL18A1,VWA1,COL7A1,COL4A5,LOXL2,ERBB2IP,SLC1A3,FBLN1,DAG1,COL12A1,TIMP3,NPNT,FRAS1,CST3,COL6A1,MATN2,DLG1,NTN4 |
| 1.624e-03 | -6.42 | exocytic vesicle | cellular component | GO:0070382 | 10 | 5 | 17570 | 1756 |
RAB6A,SYTL4,SYTL3,SYTL2,DPYSL3 |
| 1.625e-03 | -6.42 | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | 203 | 34 | 17758 | 1761 |
PARP12,GRHL2,HOXB7,HLA-E,OSGIN2,KCTD12,TRIB2,SEPP1,LGALS3BP,DAPK2,SP100,METTL7A,FJX1,TRIM21,IRF2,IFIT1,PARP9,MX1,TRIM8,PRSS23,MMD,CAPN6,SEPT6,USP18,ELK1,IFIT3,CDK5R1,FAS,CSF1,IRF7,OSR1,CMPK2,IFIH1,LIFR |
| 1.625e-03 | -6.42 | V$FOX_Q2 | MSigDB lists | V$FOX_Q2 | 203 | 34 | 17758 | 1761 |
CTHRC1,CPEB4,CHCHD7,SLC20A1,NEO1,SCML1,FOXP2,ITGA3,VASN,LMO4,MITF,TWIST1,KLF9,NCAM1,MYT1,BTBD3,MED22,CYP26B1,TGIF1,SMARCA2,SPATA18,SLC39A8,PRKAR2B,H2AFV,GABARAPL1,SWAP70,KLF12,COL13A1,NR4A3,ADAMTS14,NRG1,EIF4EBP2,TOB1,RGMA |
| 1.630e-03 | -6.42 | negative regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0043433 | 139 | 26 | 16441 | 1675 |
SIRT1,SIGIRR,THRA,DAP,ITCH,PSMD10,ERBB2IP,FZD6,WWP2,CTNNBIP1,SP100,IGF1R,BMP7,SIVA1,WFS1,NFKBIA,NOD2,NLRC5,TRIM21,ARRB1,DAB2IP,TWIST1,PIM1,CHP1,CYP1B1,EGLN1 |
| 1.638e-03 | -6.41 | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 47 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.640e-03 | -6.41 | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | 165 | 29 | 17758 | 1761 |
IER5L,PDGFC,ADAMTS2,CTHRC1,SALL4,NUAK1,FRMD6,EPHA4,ARL4C,SLC1A3,HES2,DSE,ANTXR1,COL12A1,EDNRA,TIMP3,PLOD2,ISM1,CALD1,AXL,BCL6,TRPC1,TWIST1,LTBP2,SNX10,TIAM1,ST3GAL1,CCDC88A,CYP1B1 |
| 1.642e-03 | -6.41 | HLA-A (major histocompatibility complex, class I, A) | protein interactions | 3105 | 67 | 16 | 16036 | 1726 |
HLA-E,TAP1,PDIA3,ERBB2,BCAP31,HLA-A,GNAS,APLP2,TAPBP,HLA-B,UBE2J1,ERBB3,HLA-C,LMAN1,SCARA3,TRAM1 |
| 1.642e-03 | -6.41 | low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | low_malignant_potential_(borderline)_tumour | 41 | 11 | 17775 | 1757 |
GNAS,JAK1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 1.642e-03 | -6.41 | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | MSigDB lists | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | 79 | 17 | 17758 | 1761 |
CCDC109B,SLC25A13,IQGAP1,BLVRB,NDRG2,PCTP,BCAP31,CASP4,CCDC92,CDKN2C,HDAC1,ADAM15,MARCH2,HSPB1,NXT2,DOCK9,MAPK12 |
| 1.652e-03 | -6.41 | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | 266 | 42 | 17758 | 1761 |
PAPSS2,ALDH6A1,EPAS1,CRYM,BLVRB,COL18A1,IL13RA1,SLC7A2,MGST2,ITPR2,SEPP1,SDC1,EMP2,CA2,BDH1,PLCG2,SORL1,TMBIM6,ALDH7A1,IFIT1,TINAGL1,ACOX2,ALDH3A2,FAH,CTH,PGM1,SMARCA2,SHMT1,ALDH2,AMFR,PIK3R1,ACO1,GGH,NFIB,CYB5A,ACADSB,ETS2,CGREF1,NFKBIA,PGRMC1,NRG1,TOB1 |
| 1.655e-03 | -6.40 | SH3_9 | pfam domains | PF14604 | 77 | 17 | 16629 | 1696 |
BIN1,LASP1,SORBS1,UBASH3B,MAPK8IP1,ARHGEF16,ARHGEF26,SH3KBP1,ARHGEF19,SNX18,FUT8,MAP3K9,SH3BP4,CTTN,PACSIN1,NEB,RUSC1 |
| 1.658e-03 | -6.40 | - | gene3d domains | 2.60.120.260 | 73 | 17 | 9988 | 1080 |
GUSB,EPHA4,FURIN,FBXO2,FBXO6,EPHA1,CNTNAP2,DDR1,NRP2,CNTNAP1,EPHA10,SUCO,GLB1L2,EPHB4,FBXO27,DCBLD1,PCSK5 |
| 1.672e-03 | -6.39 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | 380 | 56 | 17758 | 1761 |
RUNX2,SSH1,CPT2,CAST,ACTR8,ITGA6,EPS8,PDCL,HERC5,NENF,IL18,IL13RA1,PDGFB,CYP39A1,WWP2,DAPK2,TNS3,MDM1,ADD3,FAM46A,FUT2,CALD1,AIM1,ATP8B1,SNX16,SGK1,F2R,CNPY3,CTDSP2,SEMA3B,SSH3,ARAP2,MBP,ZNF84,TACC1,S100A4,SERTAD3,SLC35C1,ERBB2IP,YES1,H2AFV,ATP10D,CYP4F3,EDNRA,NCOA3,PLOD2,RBL1,PRCP,ITGA7,CSF1,MATN2,ERAP1,AGFG2,JAK3,ABCA1,APOL2 |
| 1.673e-03 | -6.39 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 435 | 63 | 17570 | 1756 |
SUN1,LAMP1,ANXA3,PACSIN2,IL15RA,CD63,HLA-E,ATP8A1,HLA-F,RAB23,SYTL4,PHLDA1,HLA-A,FZD6,APPBP2,SH3KBP1,MARCH8,ATP6V0B,AP1M2,ZNRF2,SNX18,N4BP3,CD9,CADPS2,RAB20,HLA-C,PACSIN1,LMAN1,WNT3A,RAB27B,MYRIP,GAD1,GPR161,SMAGP,KDELR1,LAMP3,SNX7,MYO5B,LAMP2,SYPL1,SEC23A,CLCN3,RAB3B,FZD4,SNTB2,ATP8B3,RAB38,MCFD2,C3orf58,GABARAPL1,HLA-B,GPRC5B,RAB11FIP2,TMEM30A,ITPR1,RAB11FIP1,ARRB1,GPER1,FZD5,NRGN,TBC1D4,TMEM173,ARFGEF3 |
| 1.674e-03 | -6.39 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | 121 | 23 | 17758 | 1761 |
CENPA,ZWINT,PLSCR1,FIGNL1,ITGA6,GTF2A2,PHLDA1,CASP4,RASA1,CCND1,TOP2A,RBL1,KCNN4,NFKBIA,FUT8,PLK4,AURKA,AHCY,NCAM1,ETV4,TIPARP,SLC12A2,E2F8 |
| 1.674e-03 | -6.39 | GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | MSigDB lists | GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 121 | 23 | 17758 | 1761 |
GFPT1,GAA,PPP1R2,GNPDA1,CYB5R2,SLC25A13,SLC25A27,PDIA5,BLVRA,SPR,LEPR,POR,FECH,ENPP1,DUOX1,ALDH5A1,SLC25A4,CYP4F11,DHRS2,WFS1,PHKA2,GPX4,CYP1B1 |
| 1.677e-03 | -6.39 | OSBPL6 (oxysterol binding protein-like 6) | protein interactions | 114880 | 6 | 4 | 16036 | 1726 |
PLK1,AURKA,ARRDC1,BLVRA |
| 1.677e-03 | -6.39 | PRX (periaxin) | protein interactions | 57716 | 6 | 4 | 16036 | 1726 |
EZR,DRP2,DAG1,PRX |
| 1.677e-03 | -6.39 | PLPP3 (phospholipid phosphatase 3) | protein interactions | 8613 | 6 | 4 | 16036 | 1726 |
PTEN,BCAR1,PLPP3,BCL6 |
| 1.677e-03 | -6.39 | HES6 (hes family bHLH transcription factor 6) | protein interactions | 55502 | 6 | 4 | 16036 | 1726 |
TLE1,TWIST1,HES1,PTEN |
| 1.678e-03 | -6.39 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | 188 | 32 | 17758 | 1761 |
TXN,TRIP10,PSME2,TAP1,TESK2,NRP2,FANCI,BTG3,ZNF75D,ITGB8,PASK,CDKN1B,TAGLN2,CACNA1D,TNIP1,IFITM3,RAPGEF2,BCL9,SAT1,AK4,IFIT3,DUSP4,CYB5A,CD83,TRIM9,RND3,NFKBIA,MATN2,NR4A3,CSTF2,ST3GAL1,IFI6 |
| 1.678e-03 | -6.39 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | 188 | 32 | 17758 | 1761 |
CCDC109B,PARP12,IL15RA,IL15,ATP8A1,TAP1,SELL,HERC5,LGALS3BP,TYMP,SP100,RGS3,TRIM21,PIM1,SNX10,CKAP4,GPR161,SUN2,ALDH2,IFITM3,TCF7,CD40,IFIT3,RASGRP2,SERPINA1,ITPR1,FAM117A,CCDC69,IRF7,APOL2,ABCG1,EHD1 |
| 1.679e-03 | -6.39 | condensed nuclear chromosome, centromeric region | cellular component | GO:0000780 | 19 | 7 | 17570 | 1756 |
PLK1,AURKA,REC8,BUB1,CENPA,CCNB1,NDC80 |
| 1.684e-03 | -6.39 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | 47 | 12 | 17758 | 1761 |
TNS3,RAB3B,SORT1,ENO2,PIK3AP1,TBC1D1,CORO1C,SPINT2,RYK,PRDM5,GM2A,DENND5B |
| 1.684e-03 | -6.39 | BCAT.100_UP.V1_UP | MSigDB lists | BCAT.100_UP.V1_UP | 47 | 12 | 17758 | 1761 |
ENO2,CRYM,DNAJC3,ETV5,FUT1,ABCB1,CD9,PLEKHF1,SERPINI1,DUSP4,GAD1,GCNT1 |
| 1.684e-03 | -6.39 | LEADING_EDGE | MSigDB lists | LEADING_EDGE | 47 | 12 | 17758 | 1761 |
ARAP3,S100A11,FGD6,EZR,CTTN,ARF6,BCAR1,SCYL3,CCDC88A,MYO5A,S100A6,FGD1 |
| 1.684e-03 | -6.39 | MODULE_312 | MSigDB lists | MODULE_312 | 47 | 12 | 17758 | 1761 |
BCAR3,PLK1,MX1,LGALS3,DNAJC3,CDC20,MYBL2,BCL2L1,CCNB1,STK17B,IER3,FAS |
| 1.686e-03 | -6.39 | VANTVEER_BREAST_CANCER_BRCA1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_BRCA1_DN | 41 | 11 | 17758 | 1761 |
KLHL2,UBE2Q2,MID1IP1,CA2,ZNF395,NQO1,FAM110C,SH3BP4,PRKG1,NEURL1B,SLC9A2 |
| 1.690e-03 | -6.38 | regulation of cell activation | biological process | GO:0050865 | 460 | 67 | 16441 | 1675 |
LAMP1,CASP3,IL15,INPP5D,RPS6KA1,ERBB2,IL27RA,IL18,CD274,SLC7A2,PDGFB,TNFSF9,PDGFA,CTGF,IL6ST,LMO4,IL31RA,BCL6,PIK3CA,DLG1,SLC39A10,PTPRE,RASGRP1,CD55,RIPK2,AKT1,ITCH,PRKCQ,CD40,ABR,IRS2,AXL,NOD2,F2RL1,LGALS3,SERPINE2,UBASH3B,HLA-E,TEC,PKN1,MERTK,EFNB1,HLA-A,PRKG1,IGFBP2,C10orf54,WNT3A,SYK,SOCS5,HES1,RHOA,PLSCR1,PIK3R1,PDE5A,YES1,CD83,SOX13,FAS,BANK1,PVRL2,NR4A3,PPP2R3C,GPER1,ICOSLG,JAK3,NDFIP1,AHR |
| 1.692e-03 | -6.38 | GGCAGCT,MIR-22 | MSigDB lists | GGCAGCT,MIR-22 | 219 | 36 | 17758 | 1761 |
IER5L,BIN1,HSPG2,CALM3,IL13RA1,TGFBR1,SLC1A3,TRIB2,TTYH3,ZFYVE9,CALM2,PTEN,ELF5,PIK3CD,ERBB3,CLIP2,SEPHS1,MAP3K3,SIRT1,PHF20L1,PLEKHA6,MBP,NR3C1,PTPN9,BCL9,CALM1,FURIN,PPARA,LRRC1,PDIK1L,DPYSL3,FGFR2,AGBL5,BMP1,ARRB1,STK39 |
| 1.703e-03 | -6.38 | AMIT_EGF_RESPONSE_120_HELA | MSigDB lists | AMIT_EGF_RESPONSE_120_HELA | 66 | 15 | 17758 | 1761 |
AMOTL2,IRS2,PLAUR,SAT1,ARRB1,RUNX3,GDF15,IL27RA,EPHB4,GEM,DUSP4,PHLDA1,MAFF,DAG1,CYP1B1 |
| 1.712e-03 | -6.37 | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 173 | 30 | 17758 | 1761 |
HES1,B3GNT2,TXN,RIPK2,TRIP10,NR4A1,RAPGEF2,PLAUR,SDC4,PTGER4,IL18,CD274,SAV1,CDK1,CD83,SOCS3,IER3,OTUD1,BTG3,E2F7,ETS2,MFSD2A,NFKBIA,NR4A3,NR4A2,SELK,NFKBIZ,PLD1,MAFF,NXT2 |
| 1.712e-03 | -6.37 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | 173 | 30 | 17758 | 1761 |
ATP8A1,UBASH3B,TSC22D3,ITGA6,XYLT1,EPHA4,HABP4,PDCL,ASAH1,TRIB2,DNAJB9,GABARAPL1,RASGRP2,IRS2,RALGPS2,GNPTAB,MGAT4A,PELI2,PASK,AIM1,SORL1,FAM117A,SGK1,YOD1,NR4A2,NFKBIZ,CITED2,MYLIP,C9orf72,PCSK5 |
| 1.726e-03 | -6.36 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | 196 | 33 | 17758 | 1761 |
LGALS3,CKAP2,KIF23,FBXO6,PRKACA,MNS1,IL18R1,PDIA4,TOP2A,SIVA1,PLK4,TUBG1,BUB1,CRTAP,S100A6,CENPA,SH3BGRL,RC3H2,CDC20,HTATIP2,NUSAP1,ANLN,MRPS36,CDK1,CDKN2AIPNL,RBL1,DCK,AURKA,CMPK2,F2RL1,CCNB2,ACOT7,XDH |
| 1.726e-03 | -6.36 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | 196 | 33 | 17758 | 1761 |
PLA2G4A,COL9A3,SPRED1,TTC39B,EPS8,PDIA5,FAM101B,IL18R1,EPDR1,CCND1,FAM111A,ADD3,CD9,HLA-C,C9orf72,CKAP4,IGDCC4,SOCS5,SYPL1,PLSCR1,GCLC,GGH,PCTP,STX3,NFIX,SWAP70,IDE,PRCP,CDCA7L,PRDM5,LRRK1,SERPINB1,CD33 |
| 1.729e-03 | -6.36 | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | MSigDB lists | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | 107 | 21 | 17758 | 1761 |
HMMR,CHSY3,B3GALT6,B3GNT7,B3GNT2,HSPG2,GUSB,SDC4,HEXB,DSE,B4GALT4,SDC1,GLCE,CHPF,GNS,HS6ST1,HPSE,HS3ST3B1,ARSB,ST3GAL1,NDST3 |
| 1.734e-03 | -6.36 | dendrite development | biological process | GO:0016358 | 84 | 18 | 16441 | 1675 |
CELSR2,FMN1,CIT,LRP4,SLC11A2,ARF4,IGSF9,MAP2,PTEN,BMP7,SLC9A6,DACT1,MATN2,PRKG1,ACSL4,BTBD3,SEMA3A,KLF7 |
| 1.736e-03 | -6.36 | WOO_LIVER_CANCER_RECURRENCE_UP | MSigDB lists | WOO_LIVER_CANCER_RECURRENCE_UP | 100 | 20 | 17758 | 1761 |
CCNI,ENO2,PLAUR,SOX9,DUSP4,DDR1,DPYSL3,PDGFA,CTGF,FGFR2,DPYSL2,BHLHE41,FGD6,TACSTD2,HMGA1,GEM,SGCB,S100A6,MAPK12,LAMP3 |
| 1.738e-03 | -6.35 | V$GATA1_03 | MSigDB lists | V$GATA1_03 | 235 | 38 | 17758 | 1761 |
LTBP1,PCOLCE,NF2,ENO2,DCAF7,GABRG2,NDRG2,EFNB1,ZNF385B,SYTL2,NRP2,MECOM,WWP2,ADD3,RALGPS2,GNB5,FLRT3,LHX6,ELF5,TWIST1,PIM1,ERBB3,PVRL4,HES1,FZD4,SERTAD4,FURIN,TMEM151A,CD40,PITX2,SLC9A6,FAM117A,SP6,SERPINB6,NR3C2,TOB1,CAPN1,EGLN1 |
| 1.751e-03 | -6.35 | Class I MHC mediated antigen processing & presentation | REACTOME pathways | R-HSA-983169 | 267 | 44 | 8202 | 867 |
MRC2,KLHL13,PSME2,HLA-E,HLA-F,TAP1,FBXO2,ASB9,PSMD10,PDIA3,RNF182,PSME1,FBXO6,PJA2,HLA-A,DTX3L,RNF220,PSMD1,UBE2Q2,UBE2J1,TRIM21,WWP1,HLA-C,ERAP2,SEC23A,SEC61B,PSMB4,ITCH,CDC20,UBE2A,ASB13,RNF19B,PSMA4,SOCS3,TRIM9,CTSL,HLA-B,TAPBP,TRIM69,CTSV,ERAP1,ITGAV,FBXO27,UBE2C |
| 1.753e-03 | -6.35 | zf-C4 | pfam domains | PF00105 | 46 | 12 | 16629 | 1696 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 1.754e-03 | -6.35 | V$TST1_01 | MSigDB lists | V$TST1_01 | 243 | 39 | 17758 | 1761 |
BMF,GRHL2,IGFBP6,MACC1,KLHL13,CACNA2D2,INTS8,ZNF385B,LMNA,PDGFA,AKIRIN1,SESN3,CABP1,FLRT3,BHLHE41,PLCG2,TWIST1,PIM1,CITED2,BTBD3,SMARCA2,FBLN5,MGAT4B,KIF1C,CCNF,G2E3,PITX2,MAP2,FGFR2,SIPA1L1,PGRMC1,NR4A3,INPP4B,FAM117A,KLF5,NR4A2,C1orf43,TOB1,JARID2 |
| 1.759e-03 | -6.34 | brain development | biological process | GO:0007420 | 653 | 90 | 16441 | 1675 |
EMX1,CASP3,GRHL2,NF2,HSPG2,AK7,THRA,CAST,TP53,NDRG2,STIL,PHLDA1,CALM2,TTC21B,APLP2,CDH1,DPYSL2,KIF14,LHX6,ALDH1A3,SRR,DAB2IP,DIXDC1,NOTCH3,ZBTB18,BTBD3,SPEF2,MBP,CELSR2,FZD4,TFAP2C,ARF4,ABR,NFIX,ARHGAP35,IRS2,MDK,AXL,NRG1,NRGN,ANXA3,SCN5A,CDH22,SERPINE2,ADGRG1,CALM3,CNTNAP2,SEPP1,ETS1,HOXB2,FZD6,MECOM,FOXP2,IGF1R,PTEN,GATA2,CST3,CD9,PRKG1,BAX,WNT3A,HES1,RHOA,TACC1,ASPM,RAPGEF2,CALM1,GRIN1,AK4,TCF7,SCRIB,BBS2,NFIB,CDK5R1,FAS,CDK5RAP1,PITX2,FAT4,FGFR2,TWSG1,PHLPP2,DBI,RYK,NR4A3,PCDH19,NR4A2,NDE1,WDR62,SHROOM2,SEMA3A |
| 1.762e-03 | -6.34 | Pkinase_C | pfam domains | PF00433 | 29 | 9 | 16629 | 1696 |
RPS6KA2,AKT1,CIT,RPS6KA1,STK38,SGK3,SGK1,PRKCQ,PKN1 |
| 1.766e-03 | -6.34 | V$OCT1_B | MSigDB lists | V$OCT1_B | 251 | 40 | 17758 | 1761 |
SCOC,THRA,TSC22D3,KCTD12,MRAS,MGAT5B,HPCAL4,PPP2R3A,HDAC9,SESN3,ADORA1,PTEN,CYR61,LHX6,MITF,PRKG1,CNNM4,TWIST1,TSPAN13,PIK3CD,PDE4D,CPD,SERTAD4,STAT4,SH3BGRL,KIF13A,LDB2,ITPR3,TP53INP2,DPYSL3,CXXC4,KLF12,GPRC5B,FAM117A,RHOBTB2,TMOD2,SP6,CEP41,TLL2,NR2C2 |
| 1.766e-03 | -6.34 | V$OCT1_Q6 | MSigDB lists | V$OCT1_Q6 | 251 | 40 | 17758 | 1761 |
THRA,TSC22D3,MRAS,PPP2R3A,SLC9A7,NRP2,SCML1,FOXP2,ADORA1,PTEN,RGS3,FLRT3,TSPAN13,PIK3CD,MANF,PDE4D,RIMS2,SCN3A,C9orf9,SOCS5,PDGFC,PLEKHA6,FZD4,ITCH,SH3BGRL,SERTAD4,STAT4,LDB2,ITPR3,COL12A1,DPYSL3,CXXC4,KLF12,GPRC5B,MAP2,PPP2R3C,TMOD2,SP6,TLL2,NR2C2 |
| 1.769e-03 | -6.34 | ATATGCA,MIR-448 | MSigDB lists | ATATGCA,MIR-448 | 204 | 34 | 17758 | 1761 |
SCN5A,ADD1,EPHA4,C6orf106,DNAJB11,RNF182,SH3KBP1,KCTD9,APPBP2,RAVER2,SS18,BTG3,IGF1R,IMPAD1,DACT1,XYLT2,DAPK1,WWP1,NCOA2,SOCS5,SIRT1,PLEKHA6,PRKAR2B,CASP4,GLCE,IRS2,RAB11FIP2,CDK19,RAP2C,AMMECR1,KLF5,AHR,CPEB2,DOCK9 |
| 1.772e-03 | -6.34 | E-cadherin signaling in the nascent adherens junction | Pathway Interaction DB | ecadherin_nascentaj_pathway | 33 | 12 | 2227 | 331 |
CCND1,RHOA,AKT1,CDH1,IQGAP1,PIK3R1,DLG1,PIK3CA,CTTN,NCKAP1,ARF6,TIAM1 |
| 1.772e-03 | -6.34 | regulation of integrin activation | biological process | GO:0033623 | 10 | 5 | 16441 | 1675 |
FBLIM1,PIEZO1,KIF14,FARP2,PTGER4 |
| 1.772e-03 | -6.34 | positive regulation of osteoblast proliferation | biological process | GO:0033690 | 10 | 5 | 16441 | 1675 |
CTHRC1,ITGAV,SOX8,HPSE,CYR61 |
| 1.772e-03 | -6.34 | fibroblast migration | biological process | GO:0010761 | 10 | 5 | 16441 | 1675 |
TNS1,NOV,ZFAND5,SYNE2,SGPL1 |
| 1.772e-03 | -6.34 | regulation of microvillus organization | biological process | GO:0032530 | 10 | 5 | 16441 | 1675 |
ATP8B1,EZR,KLF5,PLD1,RAP1GAP |
| 1.776e-03 | -6.33 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | 181 | 31 | 17758 | 1761 |
COL9A3,ST14,CKAP2,ASPM,INPP5D,CDC20,PDCL,SELL,CR2,MRAS,C11orf95,CYP4F3,PARM1,DHX32,SOCS3,SEMA4D,ZFP36,IQCE,BHLHE41,FOSB,KIAA0319,AURKA,SGK1,OSTF1,PIM1,PTPRE,CCNB2,F2RL1,ABCA1,EGLN1,EHD1 |
| 1.776e-03 | -6.33 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | 181 | 31 | 17758 | 1761 |
CMAS,MBP,SSH1,CAPN6,PSME2,MMADHC,FBXO2,CDCA8,OSGIN2,GABRG2,KCTD12,IL18,IL27RA,SLC25A5,ARHGEF16,CDK5R1,ELF3,MARCH8,DAZAP1,PTEN,FGFR2,PLK2,ALG13,FOSB,SORL1,NR4A2,AHCY,RAB27B,ALDH3A2,HIPK3,ABCG1 |
| 1.776e-03 | -6.33 | MODULE_179 | MSigDB lists | MODULE_179 | 431 | 62 | 17758 | 1761 |
LMTK3,FAM169A,CDH22,AASS,MRPS15,TP53,SLC25A27,C6orf106,IL13RA1,CTSZ,ISYNA1,NANS,IL18R1,CMTM6,LGALS3BP,DNAJB9,C9orf69,CYP1A1,RNF220,CDK16,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,CNOT6L,FAIM,FAR2,CITED2,GM2A,ATG4D,AMOTL2,TBC1D8B,FMN1,ADCK3,MICB,SLC39A8,PIP4K2C,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,PTPRF,AMZ2,FUCA1,NEIL1,TIMP3,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,PKIA,RRAGD |
| 1.791e-03 | -6.32 | Golgi subcompartment | cellular component | GO:0098791 | 281 | 44 | 17570 | 1756 |
PIFO,SORT1,GOLIM4,SCOC,ATP9A,ARFGEF1,RGS20,TGOLN2,RAB6A,B4GALT4,BCAP31,SLC9A7,NCS1,HLA-A,CHPF,AP1M2,FUT2,CDH1,FUT8,FUT1,SORL1,RAB27B,GCNT1,SULF2,CPD,B3GALT6,CHSY3,ATL1,COG2,FURIN,KIF13A,SLC11A2,ARFRP1,RAB38,OPTN,GNAS,GALNT3,NUCB1,WIPI1,ATP7B,GPER1,ST3GAL1,GOLGB1,ARFGEF3 |
| 1.801e-03 | -6.32 | REGULATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_PROTEIN_KINASE_ACTIVITY | 151 | 27 | 17758 | 1761 |
CCNE2,SPRED1,CDKN1C,ERBB2,HERC5,STRADB,PKMYT1,PKN1,TRIB2,MAP3K6,CARD10,CDK5R1,CCND1,CDKN2C,DIRAS3,CDK5RAP1,PTEN,RGS3,MADD,MAP3K9,MDFIC,MAP3K5,CDKN2D,HIPK3,CCDC88A,CKS2,MDFI |
| 1.806e-03 | -6.32 | canonical Wnt signaling pathway | biological process | GO:0060070 | 91 | 19 | 16441 | 1675 |
LGR4,PTPRU,FZD4,BCL9,TCF7,SDC1,FZD6,FZD7,CCND1,PTEN,PTK7,PLPP3,MITF,CDH3,DIXDC1,WNT3A,FZD5,RARG,DVL2 |
| 1.817e-03 | -6.31 | CHEBOTAEV_GR_TARGETS_UP | MSigDB lists | CHEBOTAEV_GR_TARGETS_UP | 73 | 16 | 17758 | 1761 |
NR3C1,DDIT4L,ABCG2,NDRG2,TRIB2,DOCK5,EDNRA,IL17RB,ENPP1,ADD3,ATP1A1,MGAT4A,P4HA2,ITPR1,TSPAN13,SULF2 |
| 1.821e-03 | -6.31 | MCBRYAN_PUBERTAL_BREAST_5_6WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_5_6WK_DN | 129 | 24 | 17758 | 1761 |
CPD,LASP1,SLC2A4,FZD4,SNTB2,ATP8A1,LPGAT1,SOX9,PANK1,SDC4,TNS1,ZBTB7B,NFIB,SIRPA,RAD23A,DPYSL3,NFIX,GNAS,PTEN,IL6ST,CALD1,DAPK1,EIF4EBP2,EGLN1 |
| 1.822e-03 | -6.31 | small molecule binding | molecular function | GO:0036094 | 2600 | 306 | 16491 | 1673 |
ACACB,AK7,ATP8A1,RET,TAP1,DHX8,CAMK1D,DAPK2,WEE1,UBE2T,OSBPL3,ALDH1A3,PIK3CA,AOX1,TUBG1,CRY2,PIK3CD,ACOX2,NWD1,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,CDA,PRKAR2B,KIF13A,PIF1,TP53I3,POR,ARF4,ENPP1,RBM47,DNM1L,PLK2,LIMK1,ATP7B,NOD2,DHTKD1,ITPKA,ARF6,DDX58,CDK17,NUAK1,DGKQ,RAB23,KIF23,SLC1A3,MERTK,BMP2K,RAVER2,C9orf69,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAST4,DGKG,MCCC2,PRODH,KIF20A,ADCK3,PIP4K2C,NPC2,EPHA1,ATP8B3,PCTP,GNA11,STX3,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,NRBP1,TMEM173,XDH,EGLN1,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TESK2,GRK6,AIFM2,PRKACA,DDR1,TRANK1,PDE4D,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ITPR3,ATP10D,NIN,EPHA10,JAK1,CDK19,STK26,AXL,SLC27A1,MLKL,SLC27A3,MAPK12,TNRC6C,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,DIRAS3,SLC27A6,FAM20B,SGK3,ATP8B1,MAPK11,ERBB3,OPLAH,SHMT1,RAPGEF2,GRIN1,UBE2A,AK4,YES1,KIF11,ACADSB,PLOD2,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,CENPE,LRRK1,CMPK2,CPEB2,MELK,ESYT2,NMRK1,CRYM,CAMKK1,EPHA4,VARS2,ABCD4,RAB15,RPS6KA2,PAPSS1,PASK,ABCA2,TRPC1,RAB20,RP2,MYH14,DDX59,RASGRP1,PLK1,NLRP4,ATL1,ARFRP1,ROR1,IDH1,ADRBK2,STK17B,CDK1,RHEB,P4HA2,PIK3C2B,RRAGD,PRKAA2,LMTK3,RUNX2,BVES,PEX6,ABCG2,TEC,RAB6A,DHRS3,DAZAP1,UBE2Q2,IGF1R,KIF13B,AHCY,PIM1,ABCC1,CYP26B1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,MAPKAPK2,GNAS,NUDT16,PRPS2,P4HA3,NLRC5,ALPK3,RHOBTB2,JAK3,PROM2,UGP2,UPF3B,P3H2,TP53,ERBB2,MRAS,SYTL2,CYP26A1,KIF14,FABP6,SRR,PLK4,GOT1,OAS3,EGLN3,LMAN1,SCYL3,SEPHS1,SIRT1,MAP3K3,CLCN3,AKT1,FIGNL1,MAP3K6,ATP13A2,ARHGAP35,DUOX1,ATP1A1,IDE,STK38,PTK7,PTBP3,ANXA9,AIFM3,ABCA1,PINK1,TOR4A,CPEB4,CIT,GNE,TGFBR1,CRABP2,TRIB2,M6PR,TMEM63A,TOP2A,KIF5B,ADRBK1,ADORA1,CDK16,GTF2F2,UBE2J1,SGK1,ABCD1,BUB1,SYK,RBMS2,MYO5A,ATP2B1,RHOA,RAB3B,GCLC,OGDHL,NADK2,RUNX3,DGKE,FUCA1,SWAP70,RND3,HNRNPH2,RAP2C,GEM,PLOD3,UBE2C,L1CAM,HIPK3,ZBTB33,ABCG1 |
| 1.829e-03 | -6.30 | regulation of cellular response to stress | biological process | GO:0080135 | 620 | 86 | 16441 | 1675 |
SPRED1,TXN,FOXM1,DNAJC3,EPHA4,TP53,BCL2L1,VASH1,HDAC6,ERP29,BCAP31,IER3,CTGF,DACT1,BCL6,DLG1,DUSP10,DAB2IP,TWIST1,CTTN,CDKN2D,RASGRP1,DVL2,MAP3K3,SIRT1,ERLEC1,RIPK2,AKT1,FIGNL1,FZD4,ITCH,PBK,CASP9,EZR,MAP3K6,FZD7,KDM4D,DNM1L,STK26,ANKRD6,WFS1,NOD2,F2RL1,HSPB1,GAB1,LZTS1,PRKAA2,PINK1,NKX3-1,SCOC,NUAK1,PSMD10,PKN1,PHLPP1,GSTP1,FGF19,MECOM,IGF1R,PTEN,BMP7,BAX,UBE2J1,MAP3K9,TMBIM6,MDFIC,PIKFYVE,SYK,NUP85,MDFI,FBLN5,PIK3R1,PIP4K2C,EIF2AK1,MAPK8IP1,FECH,PTPRF,MAPKAPK2,NUDT16,NR4A3,YOD1,HMGA1,FZD5,MAP3K5,NUP58,HIPK3,XDH |
| 1.832e-03 | -6.30 | GSE22886_DC_VS_MONOCYTE_DN | MSigDB lists | GSE22886_DC_VS_MONOCYTE_DN | 189 | 32 | 17758 | 1761 |
CCDC109B,ZNF395,IL15,HLA-F,TSC22D3,SELL,BTN3A1,IGF1R,SP100,CNTRL,ZFP36,MTMR11,PIK3CD,CNPY3,CDKN2D,CKAP4,GCA,ELK3,ING1,CD55,PLSCR1,C15orf39,FOS,CRISPLD2,ATP13A2,IRS2,HPSE,SERPINA1,SEMA4D,STK38,NOD2,IRF7 |
| 1.832e-03 | -6.30 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 32 | 17758 | 1761 |
RUSC2,OSGIN2,PSME1,KBTBD11,ZFYVE16,FRY,PLCG2,SLC44A1,PPP4R1,OPN3,DRAM1,MANF,MARCH2,PTPRE,PDGFC,RHOA,ALDH2,CDA,YES1,ATP10D,BCAR3,HLA-B,SWAP70,PPP2R5A,CDK19,KBTBD2,CSF1,ZDHHC7,ZMIZ1,SERPINB1,RRAGD,CD33 |
| 1.832e-03 | -6.30 | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | 189 | 32 | 17758 | 1761 |
PARP12,S100A11,F11R,HMGN3,LPIN3,CACNB4,SLC44A2,TMBIM6,IRF2,TSPAN13,TLE6,RBMS2,PARP9,MMD,NR3C1,LPGAT1,STAT4,SAT1,NUB1,PLEKHO1,NFE2L1,UTRN,IFIT3,C15orf39,PTPRF,SCARB2,TRIOBP,PRDM5,FAM117A,SERPINB1,L1CAM,JARID2 |
| 1.832e-03 | -6.30 | GSE7852_TREG_VS_TCONV_LN_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_DN | 189 | 32 | 17758 | 1761 |
EPAS1,PEX6,DAP,GPSM2,SNN,SEPP1,FAM101B,DENND2D,TTYH3,PARM1,CYP2S1,EXOC8,UBE2J1,DUSP10,FAM102A,SGK1,TAGLN2,WNT3A,ALS2CL,SLC16A5,RGMB,TCF7,ATP1B1,RASGRP2,XKRX,MAMDC4,SMTNL2,ITPR1,NR4A3,HS3ST3B1,ST3GAL1,ADAMTS16 |
| 1.832e-03 | -6.30 | GSE3982_DC_VS_MAC_DN | MSigDB lists | GSE3982_DC_VS_MAC_DN | 189 | 32 | 17758 | 1761 |
PRKAA2,GOLIM4,TSC22D3,ITGA6,CTDSPL,RGS20,TGFBR1,CCNB1,HERC6,S100A2,HOXB2,TIPRL,SLC9A7,AP1M2,RNF128,KIF13B,SORL1,CRTAP,HMMR,CENPA,PKMYT1,DCTN6,TRIM9,SERPINA1,NGFRAP1,RND3,CSF1,FAM114A1,AURKA,CENPE,CCNB2,PKIA |
| 1.832e-03 | -6.30 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 189 | 32 | 17758 | 1761 |
CD99,PPP1R2,DAP,MTL5,FBXO2,ERP29,H1FX,DAPK2,APOBEC3B,ITGA3,IMPAD1,FAM63A,FAIM,TRAM1,S100A6,FAM69A,C9orf9,GUSB,COG2,USP18,HTATIP2,EIF2AK1,MSL1,UAP1,NAT1,TLE1,CTSA,PIEZO1,SLC27A3,HSPB1,NDFIP1,ISOC1 |
| 1.832e-03 | -6.30 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_UP | 189 | 32 | 17758 | 1761 |
FBLIM1,LZTFL1,SDC4,DNAJB11,PSME1,CACNB4,RAD23A,ARHGEF10L,PTEN,TMBIM6,TRIM21,RAB20,DAB2IP,TAGLN2,TMEM37,CTTN,KCNIP3,SHMT1,CDA,HTATIP2,CD40,NCOA3,DNM1L,C19orf66,TMEM30A,NMI,ABCB1,STK39,ATP1B3,ISOC1,NRBP1,RRAGD |
| 1.832e-03 | -6.30 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | 189 | 32 | 17758 | 1761 |
PARP12,HLA-F,TAP1,HERC5,BTN3A1,PSME1,B4GALT4,HERC6,AIP,SP100,TRANK1,GNB5,RGS3,ATRNL1,TRIM21,MX1,THRB,MICB,SYNE2,BTN3A2,PDK3,IFIT3,CASP4,LEPR,OPTN,ANKRD6,CSF1,SFMBT1,IRF7,APOL2,IFI6,DOCK9 |
| 1.832e-03 | -6.30 | GSE3982_EOSINOPHIL_VS_DC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_DN | 189 | 32 | 17758 | 1761 |
CD99,MRC2,UGP2,NQO1,VANGL1,HEBP1,SDC4,BARD1,PPP2R3A,ABCD4,PDGFA,CTSC,OSBPL3,ADCK2,TRAM1,GM2A,CCDC88A,WBP5,ALDH2,MRPS33,ACO1,SESN1,ALCAM,RHEB,CD83,OTUB2,MDH1,PIK3C2B,HSPB1,CCNB2,ACOT7,PCSK5 |
| 1.835e-03 | -6.30 | V$PU1_Q6 | MSigDB lists | V$PU1_Q6 | 220 | 36 | 17758 | 1761 |
SEMA6B,C6orf106,IL18,PKN1,FAM81A,DPP8,SIRPA,H1FX,IRF2BPL,ST5,SESN3,ADORA1,RINL,ATP5H,FUT8,ADAM15,TWIST1,RAB20,CNOT6L,PLCB2,RHOA,TFAP2C,PPP1R14C,GLT8D2,ONECUT1,ACVRL1,CSF1,PTK7,SP6,CTSA,PIEZO1,SLC27A3,JARID2,PCSK5,ARHGEF4,NR2C2 |
| 1.836e-03 | -6.30 | PPA1 (pyrophosphatase (inorganic) 1) | protein interactions | 5464 | 33 | 10 | 16036 | 1726 |
AKT1,WIPI1,TP53,HDAC1,GLO1,FBXO6,PLIN3,HDAC6,HSPB1,AIP |
| 1.836e-03 | -6.30 | HSPG2 (heparan sulfate proteoglycan 2) | protein interactions | 3339 | 33 | 10 | 16036 | 1726 |
GRN,PDGFA,CTGF,COL13A1,BMP1,VWA1,TINAGL1,FBXO6,PDGFB,FBLN1 |
| 1.836e-03 | -6.30 | CDK16 (cyclin-dependent kinase 16) | protein interactions | 5127 | 33 | 10 | 16036 | 1726 |
SEC23A,CDK17,CDK16,CDK18,PRKACA,PPP2R2D,CDK5R1,LMNA,SH3KBP1,APPBP2 |
| 1.839e-03 | -6.30 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 60 | 14 | 17758 | 1761 |
GNAS,PITX2,LTBP1,ZNF75D,GOLIM4,TWSG1,LMO4,EPHA4,SGK1,PRKAR2B,MDFIC,LIFR,STK17B,SCML1 |
| 1.842e-03 | -6.30 | bone development | biological process | GO:0060348 | 162 | 29 | 16441 | 1675 |
CYP26B1,PDGFC,RHOA,RUNX2,PAPSS2,HSPG2,ANO6,AMER1,SOX9,PTGER4,RAB23,OSR2,DHRS3,PLS3,PDGFA,GNAS,PITX2,FAT4,COL13A1,FGFR2,SEMA4D,MEGF8,IMPAD1,TFAP2A,TWIST1,LRRK1,RARG,SP5,SULF2 |
| 1.844e-03 | -6.30 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | 30 | 9 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,IDH1,GNA11 |
| 1.855e-03 | -6.29 | MODULE_44 | MSigDB lists | MODULE_44 | 316 | 48 | 17758 | 1761 |
GRN,HSPG2,S100A11,TSC22D3,INPP5D,ITGA6,TAP1,SELL,ASAH1,IL27RA,NUCB2,TRIB2,SEPP1,DHRS3,SDC1,ETS1,TSPAN7,M6PR,TYMP,SP100,TRANK1,CDH1,CTSC,SH3BP1,LMO4,COL6A1,BCL6,TACSTD2,IGFBP2,IFIT1,LGMN,CYP1B1,LAMP3,MX1,COL6A2,PLSCR1,S100A4,SEPT6,PIK3R1,TCF7,ARHGDIB,IFIT3,CASP4,FUCA1,ENPP1,JAK1,ITPR1,OCLN |
| 1.859e-03 | -6.29 | V$USF_Q6_01 | MSigDB lists | V$USF_Q6_01 | 228 | 37 | 17758 | 1761 |
IER5L,LAMP1,HOXB7,SNN,PKN1,TFAP4,WEE1,ARTN,CDH1,BHLHE41,FAM13B,RANBP1,BAX,ANKRD12,SGK1,EPB41L4B,SOCS5,SIRT1,LONRF3,SNTB2,ELOVL3,TFAP2C,TCF7,ELK1,ABR,GNAS,WIPI1,HNRNPH2,UTP14C,KBTBD2,HOXA9,ATP7B,SYT13,GLA,C1orf43,NR3C2,RAB3IL1 |
| 1.878e-03 | -6.28 | intracellular lipid transport | biological process | GO:0032365 | 19 | 7 | 16441 | 1675 |
PRKAA2,ACACB,NPC2,PRKAG2,CPT2,ABCA1,ABCG1 |
| 1.879e-03 | -6.28 | V$IRF1_01 | MSigDB lists | V$IRF1_01 | 236 | 38 | 17758 | 1761 |
DDX58,SORBS1,IL15RA,SCOC,HOXB7,EPAS1,TAP1,CCDC68,AKIRIN1,DTX3L,RNF220,LMO4,MITF,DLG1,FXYD5,DUSP10,TRIM21,TWIST1,HLA-C,RIMS2,PDGFC,PCGF5,TRIM8,USP18,SH3BGRL,SAT1,SYNE2,RGAG1,LDB2,NFIX,PITX2,TAPBP,NGFRAP1,LTBP2,LEMD1,NR3C2,EHD1,DOCK9 |
| 1.881e-03 | -6.28 | HALLMARK_INFLAMMATORY_RESPONSE | MSigDB lists | HALLMARK_INFLAMMATORY_RESPONSE | 197 | 33 | 17758 | 1761 |
IL15RA,IL15,CD82,SELL,IL18,SLC7A2,IL18R1,TNFSF9,ITGB8,CD70,PTPRE,RASGRP1,ATP2B1,LAMP3,CD55,RIPK2,PLAUR,PTGER4,SLC11A2,CD40,TAPBP,SLC4A4,SEMA4D,AXL,CSF1,NMI,NFKBIA,NOD2,IRF7,FZD5,ICOSLG,ABCA1,AHR |
| 1.881e-03 | -6.28 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | 197 | 33 | 17758 | 1761 |
CASP3,ARHGEF3,PARP12,SERPINE2,PTTG1,TESK2,EFHD2,PHLDA1,SYTL2,FAM111A,NOV,WEE1,MGAT4A,IL6ST,TPST1,TSPAN13,PACSIN1,RASGRP1,CENPA,ARAP2,CDC20,MBNL3,CDK1,CD83,CMTM7,KLHL2,PRKAG2,PTER,ITPR1,CAB39,TBC1D4,TRAF5,ISOC1 |
| 1.882e-03 | -6.28 | regulation of alpha-beta T cell proliferation | biological process | GO:0046640 | 24 | 8 | 16441 | 1675 |
CD55,RIPK2,ITCH,HLA-E,IL18,C10orf54,SYK,HLA-A |
| 1.885e-03 | -6.27 | regulation of neuron apoptotic process | biological process | GO:0043523 | 192 | 33 | 16441 | 1675 |
CASP3,GCLM,PINK1,TRIM2,CPEB4,NQO1,TP53,BCL2L1,SIX4,KIF14,PIK3CA,BAX,TFAP2A,ERBB3,LGMN,EGLN3,F2R,RHOA,KCNIP3,GCLC,CASP9,OXR1,GRIN1,CDK5R1,RASA1,OPTN,MDK,BHLHB9,AXL,WFS1,NR4A3,NR4A2,UNC5B |
| 1.886e-03 | -6.27 | PID_AURORA_A_PATHWAY | MSigDB lists | PID_AURORA_A_PATHWAY | 30 | 9 | 17758 | 1761 |
CENPA,DLGAP5,AKT1,TACC1,NFKBIA,TP53,AURKA,PRKACA,RASA1 |
| 1.886e-03 | -6.27 | PID_NECTIN_PATHWAY | MSigDB lists | PID_NECTIN_PATHWAY | 30 | 9 | 17758 | 1761 |
CDH1,PVRL2,IQGAP1,PIK3R1,PIK3CA,F11R,ITGAV,PDGFB,FARP2 |
| 1.886e-03 | -6.27 | Tetraspanin | interpro domains | IPR000301 | 30 | 9 | 18293 | 1814 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,TSPAN7 |
| 1.887e-03 | -6.27 | single-organism transport | biological process | GO:0044765 | 3092 | 360 | 16441 | 1675 |
LAMP1,SLC35D2,ACACB,ADD1,TSC22D3,SLC25A13,ATP8A1,CACNA2D2,TAP1,TGOLN2,SYTL4,SLC20A1,SLC9A7,NCS1,CALM2,PQLC2,AP1M2,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,TINAGL1,PIK3CD,TMEM37,PACSIN1,XKR8,LAMP2,ORAI2,SLC35C1,PRKAR2B,KIF13A,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,ENPP1,PLCG1,SLC25A4,LIMK1,GNPTAB,ATP7B,TRAF3IP1,NOD2,SARAF,F2RL1,SCN5A,NFKBIE,SLC25A27,NDUFA4,SLC36A4,SLC1A3,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,DOPEY2,SNX18,ATP5H,RIMS3,RPL39,SLC16A6,PCYOX1,SORL1,CADPS2,PANX2,CACNA1D,PIKFYVE,SYTL3,NUP85,PPP6R1,RIMS2,TRAK2,PMPCB,KCNJ12,SLC37A1,MFI2,CALM1,ANO6,ERO1A,NPC2,ATP8B3,PCTP,SFXN5,STX3,CYB5A,SLCO4A1,CACHD1,AP1AR,GABRD,SCARB2,PRKAG2,SLC4A4,TIMM8A,ITPR1,SLC4A3,NDE1,ARPC2,HOOK1,NRBP1,NUP58,XDH,EHD1,PLA2G4A,MFSD3,MTM1,CCDC109B,SLC2A4,RALBP1,ATP2C2,FTH1,BCL2L1,PRKACA,DDR1,ZFYVE9,CCND1,SCNN1A,CDKN1B,CNNM4,ACSL4,ARL4D,RAB27B,SCN3A,ATG4D,MYO5B,SEC23A,SEC61B,COG2,FZD4,KIF1C,SLC11A2,ATP1B1,RAB38,ITPR3,ATP10D,DDOST,CORO1C,AXL,SLC9A6,SLC27A1,SLC25A30,DENND5B,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,CYB561,ANO9,SLC25A43,PDIA4,SLC25A36,ADD3,SLC27A6,CTSC,SGK3,CD9,BAX,KLC3,ATP8B1,SLC44A2,WWP1,SLC16A5,TPCN1,S100A6,NCOA2,LCA5,ZC3H11A,PIK3R1,MRS2,GRIN1,FURIN,YES1,NEURL1B,CPTP,GPLD1,RPL12,FGFR2,RAB11FIP2,SYT7,ABCB1,NR4A3,GRIN2D,ITGAV,ARSB,USF2,CYBRD1,ESYT2,EXPH5,CRYM,CPT2,ARFGEF1,F11R,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,SLC8B1,TMC1,ABCD4,ZFYVE16,RAB15,DPYSL2,SLC44A1,ABCA2,TRPC1,RAB20,RP2,SLC39A10,ANO4,TRAM1,S100A13,RASGRP1,KCNIP3,CELSR2,EZR,ARFRP1,ADRBK2,OPTN,EDNRA,TRIM9,KCNMB4,KCNK1,WIPI1,RAB11FIP1,PIEZO1,PCSK5,PRKAA2,GRN,LASP1,PEX6,FXYD3,SLC22A31,ABCG2,CALM3,NCKAP1,RAB6A,ANO1,CA2,GATA2,KIF13B,KCNN4,EXOC8,FXYD5,SELK,GAD1,SLC12A2,ABCC1,BTN3A2,STRADB,SCRIB,EIF2AK1,MFSD7,STEAP1,GNAS,SLC6A6,TMEM30A,MFSD2A,NFKBIA,SLC2A6,SH3BP4,ZDHHC7,PITPNA,LTBP2,ATP1B3,PLD1,SHROOM2,JAK3,TOB1,APOL2,NIPA1,SLC25A24,SORBS1,UPF3B,TP53,SLC7A2,EMP2,BCAP31,SYTL2,TTC21B,PDGFA,SLC25A48,ATP6V0B,SVBP,KIF14,ZDHHC12,FABP6,PLCG2,BCL6,ZDHHC23,RPN2,LMAN1,SCN2A,F2R,GM2A,CHP1,PPIF,CLCN3,AKT1,SLC39A8,OSTM1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,ALDH5A1,PEX2,SPTBN5,SYT13,ABCA1,ANXA3,SORT1,MFSD14B,CD63,GABRG2,AIP,VPS26A,SLC9A2,HMGXB4,ZDHHC21,M6PR,TMEM63A,KIF5B,ADORA1,ADRBK1,CDK16,LLGL2,SGK1,ABCD1,SYK,MYO5A,ATP2B1,HES1,RAB3B,FBLN5,PPARA,PRICKLE1,COL7A1,BBS2,SCRN2,SERPINA1,SCG2,TMC5,ARRB1,MCUR1,SPCS3,NDFIP1,ARHGEF9,ABCG1,SNPH |
| 1.889e-03 | -6.27 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 349 | 52 | 17758 | 1761 |
FRMD4A,TSPAN15,GGA1,ATP2C2,CACNA2D2,LMCD1,CYB561,NUCB2,EMP2,FAM46C,CCND1,ZFYVE16,DOPEY2,MLPH,LLGL2,SLC16A6,IQCE,MGAT4A,ATP8B1,TMBIM6,TSPAN13,ERBB3,CACNA1D,DLG3,SCYL3,MCCC2,MYO5B,CAMSAP3,ZNF84,KIFC2,TNIP1,SLC37A1,TESK1,FZD4,HMG20B,SPTLC2,ARHGEF26,SOX13,EPN3,PTPRF,ENPP1,TJP3,PVRL2,ABHD12,WFS1,ZNF704,ARRB1,ANXA9,ZMIZ1,TOB1,RUSC1,ABCG1 |
| 1.890e-03 | -6.27 | Golgi cisterna | cellular component | GO:0031985 | 93 | 19 | 17570 | 1756 |
CHSY3,B3GALT6,ATL1,SORT1,GOLIM4,FURIN,B4GALT4,BCAP31,HLA-A,NCS1,CHPF,GALNT3,NUCB1,FUT2,FUT8,FUT1,SORL1,ST3GAL1,GCNT1 |
| 1.890e-03 | -6.27 | Aldedh | pfam domains | PF00171 | 19 | 7 | 16629 | 1696 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.896e-03 | -6.27 | skin epidermis development | biological process | GO:0098773 | 78 | 17 | 16441 | 1675 |
LGR4,LRP4,SOX9,TFAP2C,SAV1,LDB2,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,DBI,CTSV,HDAC1,HOXC13 |
| 1.909e-03 | -6.26 | PROTEIN_AMINO_ACID_PHOSPHORYLATION | MSigDB lists | PROTEIN_AMINO_ACID_PHOSPHORYLATION | 276 | 43 | 17758 | 1761 |
PRKAA2,CDK17,PINK1,NF2,RET,ERBB2,TESK2,TGFBR1,PKN1,TRIB2,MERTK,CCND1,DAPK2,IGF1R,CDK16,IL31RA,SGK3,MAP3K9,PLK4,DAPK1,PRKG1,SGK1,PIM1,ERBB3,F2R,CCDC88A,MAP3K3,AKT1,STRADB,EIF2AK1,MAP3K6,STK17B,PRDX4,STK17A,MAPKAPK2,ACVRL1,STK38,LIMK1,NR4A3,AURKA,JAK3,HIPK3,MAPK12 |
| 1.910e-03 | -6.26 | CACTGCC,MIR-34A,MIR-34C,MIR-449 | MSigDB lists | CACTGCC,MIR-34A,MIR-34C,MIR-449 | 268 | 42 | 17758 | 1761 |
CCNE2,FRMD4A,LGR4,XYLT1,OSGIN2,CNTNAP2,GRK6,MGAT5B,FAM167A,PPP2R3A,TMCC3,RALGPS2,MGAT4A,FUT8,BCL6,ZDHHC23,SLC44A2,VAT1,DIXDC1,ACSL4,IQGAP3,NCEH1,MYRIP,PGM1,CAPN6,FOXJ2,NFE2L1,VEZT,ALCAM,ABR,COL12A1,GLCE,CNTNAP1,PPP2R5A,KLF12,AXL,CORO1C,CSNK1G1,FGD6,NR4A2,RARG,PKIA |
| 1.910e-03 | -6.26 | STK33_UP | MSigDB lists | STK33_UP | 268 | 42 | 17758 | 1761 |
UNKL,SPRED1,BMF,CPEB4,NUAK1,GDF15,FAM198B,PHLDA1,OTUD1,SIPA1L2,BTG3,NOV,KIAA1107,ITGB8,ZFP36,IL6ST,CD9,BCL6,DAPK1,ANKRD12,CDKN1B,SGK1,SNX16,C10orf54,NCEH1,SULF2,GFPT1,DOCK4,TGIF1,OSTM1,COQ10B,FNDC3A,RNF19B,FOS,GLCE,SCG2,RND3,LIMK1,CPEB2,ABCA1,MAFF,CYBRD1 |
| 1.915e-03 | -6.26 | Thyroid hormone signaling pathway | KEGG pathways | hsa04919 | 118 | 24 | 6908 | 758 |
THRB,AKT1,THRA,CASP9,PIK3R1,TP53,ATP1B1,PRKACA,RHEB,CCND1,PLCG1,NCOA3,ATP1A1,PLCG2,PIK3CA,HDAC1,ATP1B3,NOTCH3,ITGAV,PIK3CD,TBC1D4,PLCB2,MED30,NCOA2 |
| 1.917e-03 | -6.26 | fibrous_tissue_and_uncertain_origin | COSMIC cancer mutations | fibrous_tissue_and_uncertain_origin | 285 | 44 | 17775 | 1757 |
ATP9A,RET,TP53,ERBB2,CNTNAP2,NUCB2,CARD10,ZFYVE9,KIF5B,CDKN2C,SS18,ACAP2,ITGB8,CDH1,PTEN,FRYL,ABCA2,PIK3CA,SORL1,C8orf58,PAQR7,ENPP4,KCNJ12,SGCE,ATL1,LCA5,AKT1,NR3C1,CASP9,PIK3R1,IDH1,TXNDC11,BCAR1,GNA11,PRX,GNAS,CDK5RAP1,DNAJC10,CDK19,FGFR2,SLC2A6,TRAF5,JAK3,LZTS1 |
| 1.918e-03 | -6.26 | SAM/pointed | interpro domains | IPR013761 | 115 | 22 | 18293 | 1814 |
ARAP3,ARAP2,EPHA4,PPFIBP2,SAMD9,EPHA1,ETS1,MAP3K6,SCML1,ELF3,DGKH,EPHA10,GAREM2,ANKS6,ETS2,ANKS1B,STIM1,ELF5,SFMBT1,EPHB4,MAP3K5,ETV7 |
| 1.942e-03 | -6.24 | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | 182 | 31 | 17758 | 1761 |
PCGF5,ARAP2,TXN,SPC25,TNIP1,RIPK2,IL15,PSME2,STAT4,LYRM1,C3orf52,NUB1,CRISPLD2,OPTN,SOCS3,GALNT3,DTX3L,RCN1,SERPINA1,UAP1,ITGB8,NMI,SIPA1L1,DRAM1,SPTBN5,IRF7,SERPINB1,JAK3,SEMA3A,F2R,COBL |
| 1.945e-03 | -6.24 | SASSON_RESPONSE_TO_FORSKOLIN_UP | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_UP | 87 | 18 | 17758 | 1761 |
CD55,CASP9,COL18A1,EZR,GNAS,PSMD1,GPRC5B,GDE1,CDK16,P4HA2,ITPR1,PGRMC1,TMBIM6,SGK1,PHKA2,MAP3K5,PLIN3,ATP2B1 |
| 1.949e-03 | -6.24 | CYCLINS | prosite domains | PS00292 | 10 | 5 | 11866 | 1235 |
CCNE2,CCND1,CCNF,CCNB1,CCNB2 |
| 1.950e-03 | -6.24 | ZHANG_TLX_TARGETS_DN | MSigDB lists | ZHANG_TLX_TARGETS_DN | 108 | 21 | 17758 | 1761 |
TIMP2,SORBS1,S100A11,NR4A1,S100A4,SAT1,TAP1,SIRPA,GABARAPL1,PDGFA,SCARB2,CSF1,BAX,AOX1,OPN3,PLEKHF1,CITED2,PTPRE,TOB1,CPPED1,IGDCC4 |
| 1.958e-03 | -6.24 | PID_TAP63_PATHWAY | MSigDB lists | PID_TAP63_PATHWAY | 54 | 13 | 17758 | 1761 |
PLK1,ITGA3,NQO1,SPATA18,ITCH,BAX,TFAP2C,WWP1,GDF15,DHRS3,S100A2,TP53I3,FAS |
| 1.962e-03 | -6.23 | Nuclear Receptor transcription pathway | REACTOME pathways | R-HSA-383280 | 51 | 13 | 8202 | 867 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,NR3C2,RARG,NRBP1,NR2C1,NR2C2 |
| 1.967e-03 | -6.23 | GGCAGTG,MIR-324-3P | MSigDB lists | GGCAGTG,MIR-324-3P | 94 | 19 | 17758 | 1761 |
MBP,FZD4,CIT,ETV5,COL7A1,FTH1,RAB6A,SLC20A1,DAG1,EDNRA,PIAS3,SHROOM3,WDR44,FGFR2,PTER,RIMS3,RAP2C,RGS14,ABCA1 |
| 1.973e-03 | -6.23 | JAK2 (Janus kinase 2) | protein interactions | 3717 | 120 | 24 | 16036 | 1726 |
HES1,UBASH3B,CALM1,PIK3R1,ERBB2,TEC,YES1,LEPR,SIRPA,SOCS3,IRS2,DTX3L,MDK,RCN1,PLCG1,PPP2R5A,IGF1R,IL6ST,PLCG2,NFKBIA,CDKN1B,ERBB3,MAP3K5,JAK3 |
| 1.974e-03 | -6.23 | SOCS1 (suppressor of cytokine signaling 1) | protein interactions | 8651 | 62 | 15 | 16036 | 1726 |
IRS2,TRIM8,IGF1R,JAK1,PTEN,CSF1,AXL,PIK3R1,TP53,TUBG1,ERBB2,TEC,MAP3K5,JAK3,RASA1 |
| 1.978e-03 | -6.23 | EPN1 (epsin 1) | protein interactions | 29924 | 56 | 14 | 16036 | 1726 |
GAS2L1,EPN3,SCNN1A,AP1M2,REPS2,RALBP1,PIK3R1,TFAP2A,ARRDC1,GTF3A,BCAR1,CDK1,OCLN,EHD1 |
| 1.980e-03 | -6.22 | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 167 | 29 | 17758 | 1761 |
RIPK2,PLAUR,RAPGEF2,SDC4,SLC11A2,IL18,CD274,SLC1A3,SAV1,DNER,RNF19B,CDK1,CD83,SOCS3,IER3,BTG3,E2F7,ITGB8,ETS2,MFSD2A,ZFP36,SLC2A6,RAP2C,NFKBIA,DRAM1,NFKBIZ,SNX10,NIPA1,EHD1 |
| 1.991e-03 | -6.22 | pancreas-other-dysplasia-in_situ_neoplasm | COSMIC cancer mutations | pancreas-other-dysplasia-in_situ_neoplasm | 48 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.991e-03 | -6.22 | dysplasia-in_situ_neoplasm | COSMIC cancer mutations | dysplasia-in_situ_neoplasm | 48 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.996e-03 | -6.22 | GEORGANTAS_HSC_MARKERS | MSigDB lists | GEORGANTAS_HSC_MARKERS | 67 | 15 | 17758 | 1761 |
TRIM8,HLF,H1F0,HLA-E,IL6ST,RAPGEF2,FOSB,INPP4B,LIMCH1,FAM198B,HSPB1,TIPARP,CYBRD1,PLS3,MECOM |
| 1.996e-03 | -6.22 | SMALL_GTPASE_REGULATOR_ACTIVITY | MSigDB lists | SMALL_GTPASE_REGULATOR_ACTIVITY | 67 | 15 | 17758 | 1761 |
ARHGEF10L,DOCK4,ARHGEF3,ARAP3,ARHGEF11,RAPGEF2,RALBP1,RASA2,MADD,RANBP1,ARFGEF1,ARHGDIB,TIAM1,RASA1,FARP2 |
| 1.996e-03 | -6.22 | BROWNE_INTERFERON_RESPONSIVE_GENES | MSigDB lists | BROWNE_INTERFERON_RESPONSIVE_GENES | 67 | 15 | 17758 | 1761 |
MX1,TYMP,SP100,IL15RA,PLSCR1,IL15,HLA-F,NMI,TAP1,TRIM21,IRF7,IFIT3,IFI6,APOBEC3G,MELK |
| 1.996e-03 | -6.22 | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | MSigDB lists | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 67 | 15 | 17758 | 1761 |
IRS2,PRKAA2,ACACB,SLC2A4,PRKAG2,NFKBIE,AKT1,CAMKK1,NFKBIA,PPARA,ADIPOR1,PRKCQ,ACSL4,LEPR,SOCS3 |
| 1.999e-03 | -6.22 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | 190 | 32 | 17758 | 1761 |
LASP1,RASA2,TAP1,MGST2,CAMK1D,HERC6,B4GALNT1,IRF2BPL,SETDB2,UBE2J1,TMEM64,OAS3,S100A13,C9orf72,PARP9,DOCK4,SMARCA2,TIMP2,ARAP2,TNIP1,FOXJ2,ATP1B1,XKRX,NCOA3,DOLPP1,MADD,LRIG1,TRIOBP,NR4A2,TOB1,RARG,JARID2 |
| 1.999e-03 | -6.22 | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | 190 | 32 | 17758 | 1761 |
SLC2A4,ARMCX3,EPAS1,PDIA5,TEX2,TP53I11,TMEM170B,CRABP2,ETS1,ARHGEF16,APOBEC3B,MLPH,UBE2T,ELMO2,SLC16A6,GALNS,MANF,F2R,NEB,CORO2A,GCLC,EZR,RUNX3,TXNDC11,ALCAM,G2E3,LRRC42,PELI2,HMGA1,CMPK2,SHROOM2,HOXC13 |
| 1.999e-03 | -6.22 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | 190 | 32 | 17758 | 1761 |
DLGAP5,HJURP,PTTG1,CDCA8,ITPR2,CCNB1,CENPN,IL18R1,FANCI,DAZAP1,FUT8,PLK4,BUB1,CKS2,ZWINT,CENPA,CDC20,CASP9,MYBL2,NUSAP1,DUSP4,KIF11,SLCO4A1,AURKA,CSTF2,DONSON,EIF4EBP2,CENPE,CCNB2,UBE2C,NCAPG2,MELK |
| 1.999e-03 | -6.22 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 190 | 32 | 17758 | 1761 |
SLC25A24,ATP8A1,TAP1,TP53,SELL,NKRF,SLC36A4,DSE,HERC6,LGALS3BP,SIRPA,IL17RB,FAM189A1,CTSC,RIMS3,UBE2J1,RPN2,ALS2CL,MED22,XKR8,PARP9,NWD1,SPEF2,TIMP2,NR4A1,PTGER4,LITAF,RUNX3,SWAP70,MADD,F2RL1,NDFIP1 |
| 1.999e-03 | -6.22 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 190 | 32 | 17758 | 1761 |
GRN,TXN,IL15,DNAJC3,PDIA3,PSME1,ISYNA1,CRABP2,MERTK,PHLDA1,FAM46C,CMTM6,NOV,RRBP1,CST3,ECE1,NAGA,SEPT6,ITCH,GCLC,CASP9,ARFRP1,NPC2,FNDC3A,RNF19B,DOCK5,STX3,CMTM7,FUCA1,NUCB1,TMEM30A,ISOC1 |
| 2.000e-03 | -6.21 | AAGCACA,MIR-218 | MSigDB lists | AAGCACA,MIR-218 | 383 | 56 | 17758 | 1761 |
LASP1,SPRED1,PARP12,RUNX2,FRMD4A,LGR4,CTDSPL,RET,RAB6A,TTYH3,KCTD9,FANCI,AKIRIN1,RNF220,UBE2Q2,RPS6KA2,CA2,IMPAD1,RIMS3,FLRT3,KLF3,MITF,PRKG1,ZDHHC23,VAT1,ANO4,SLC12A2,CCDC88A,KCNIP3,TBC1D8B,NR3C1,FZD4,TACC1,BCL9,EIF5A2,PIK3R1,TMEM151A,PRKAR2B,ATP1B1,RNF19B,GLCE,SOCS3,NFIX,GALNT3,TRIM9,PLCG1,HLF,PPP2R5A,KLF12,DOLPP1,SFMBT1,HS3ST3B1,SYT13,ZMIZ1,LIFR,TOB1 |
| 2.011e-03 | -6.21 | V$ELF1_Q6 | MSigDB lists | V$ELF1_Q6 | 229 | 37 | 17758 | 1761 |
CMAS,PSME2,IQGAP1,FAM134A,CD274,ITPR2,CAMK1D,PKN1,DPP8,SIX4,ZNF687,ADD3,STIM1,SHC3,MITF,SORL1,TWIST1,PIK3CD,ACSL4,NCAM1,CNOT6L,PLCB2,FBLN5,SAT1,TFAP2C,ARHGDIB,PLEKHH2,KLF12,CSF1,MADD,PRDM5,VSIG10,CTSA,C1orf43,ARPC2,JARID2,NR2C2 |
| 2.022e-03 | -6.20 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 484 | 68 | 17758 | 1761 |
GAS2L1,MYL9,REPS2,RALBP1,COL18A1,NDRG2,FAM46C,ST5,FRYL,SLC44A1,ACSL4,ACOX2,CTTN,MARCH2,TMEM9,NWD1,CLCN3,COL6A2,CITED4,SLC39A8,PRKAR2B,LOXL2,ZFAND5,ALCAM,IRS2,SLC25A4,DNM1L,FAM114A1,HS3ST3B1,ST3GAL1,ABCA1,GCLM,CPEB4,DNAJB2,ABCG2,RAB6A,TSPAN7,NRP2,HLA-A,BMP2K,FOXP2,TOP2A,MLPH,RNF128,IGF1R,CALD1,SLC44A2,IGFBP2,C2orf72,WBP5,IGSF3,EPB41L5,CRB3,MFSD2B,EIF5A2,FBXO9,EIF2AK1,SNTB1,BCAR1,PTPRF,FECH,TIMP3,FGFR2,TMEM30A,CSNK1G1,RYK,FZD5,PER3 |
| 2.025e-03 | -6.20 | microtubule organizing center | cellular component | GO:0005815 | 608 | 83 | 17570 | 1756 |
DYNLRB1,SORBS1,CEP70,DLGAP5,UPF3B,ACTR8,NDRG2,BCL2L1,SYTL4,CCNB1,PRKACA,STIL,CALM2,LRRC45,CNTRL,CEP78,PLK4,ABCA2,TUBG1,HYLS1,RP2,PDE4D,ZNF365,SNX10,CCDC38,PLK1,CAMSAP3,PCGF5,AKT1,CCSAP,CDC20,EZR,PRKAR2B,KIF13A,CCNF,CDK1,NIN,CEP162,DZIP1L,NEIL1,STK26,PLK2,TRAF3IP1,FAM110C,TRIOBP,RGS14,TRAF5,TTC8,PIFO,CKAP2,POC1B,RASSF7,KIF23,CALM3,SAC3D1,KIF5B,TOP2A,CCDC92,FRY,PHF7,NEK2,TFAP2A,LRIF1,MPHOSPH9,LCA5,TACC1,CALM1,RGCC,YES1,BBS2,NUBP1,DCTN6,MAPKAPK2,AURKA,MDH1,PPP2R3C,NDE1,CFAP20,CEP41,WDR62,CCNB2,ESPL1,DIS3L |
| 2.029e-03 | -6.20 | V$HNF4_01_B | MSigDB lists | V$HNF4_01_B | 237 | 38 | 17758 | 1761 |
TP53,C6orf106,ERBB2,NRG2,CALM3,MPP5,TEX2,CRABP2,SEPP1,PRKACA,FBLN1,CALM2,AIM1L,RAB15,CYP1A1,IGF1R,CDK16,KLF3,FUT8,DAB2IP,CRY2,TSPAN13,NR2C1,LAMP2,TGIF1,NR4A1,SERTAD4,CALM1,PPARA,CDK5R1,HOXA9,TLE1,MRPS28,UNC5B,REEP4,ACOT7,EHD1,DIS3L |
| 2.030e-03 | -6.20 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 293 | 45 | 17758 | 1761 |
LTBP1,LGR4,ZCCHC24,ARL4C,MRAS,SNN,TRIB2,SH3KBP1,RCN1,E2F7,RPS6KA2,ANKS1B,MITF,DAPK1,POF1B,NTN4,PIM1,NCEH1,SLC12A2,TMEM200B,ACBD5,NFE2L3,ZNF462,ACVR1C,STRADB,XKRX,ALDH5A1,SLC4A4,ACADSB,PLOD2,KCNK1,MAP2,CSNK1G1,PTER,PELI2,AMMECR1,RAP2C,STK39,HMGA1,REEP4,TBC1D4,TOB1,CMTM4,FGD1,EHD1 |
| 2.030e-03 | -6.20 | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 293 | 45 | 17758 | 1761 |
LTBP1,GAA,ATP2C2,COL18A1,PHLPP1,DNER,C11orf95,FGF19,MECOM,IGF1R,ANKS1B,FLRT3,TMEM37,ZRANB1,SLC12A2,ETV4,NFE2L3,HES1,PCDH1,ALDH2,LCA5,PSMB4,FZD4,CBX6,UTRN,TMEM144,PRKCQ,TNS1,ARFRP1,ATP1B1,LDB2,PITX2,TAPBP,HLF,GPRC5B,FAAH,SHROOM3,MATN2,CLIP4,PRKCDBP,GLA,CBX7,OCLN,DEF6,DOCK9 |
| 2.031e-03 | -6.20 | DAG and IP3 signaling | REACTOME pathways | R-HSA-1489509 | 34 | 10 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,ITPR1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 2.034e-03 | -6.20 | vpu (p16) | protein interactions | 155945 | 241 | 41 | 16036 | 1726 |
LAMP1,CASP3,CD63,HLA-E,CD82,HLA-F,TMEM55B,TP53,ARFGEF1,SELL,TGFBR1,TGOLN2,BCL2L1,TSPAN7,HLA-A,SGPL1,CD109,CDH1,ATP5H,RANBP1,FOSB,BAX,IGFBP2,IFIT1,HLA-C,APOBEC3G,ATP2B1,CHP1,LAMP2,MX1,PLK1,IFIT3,CD40,FOS,CD83,FAS,CNTNAP1,HLA-B,SEMA4D,NFKBIA,AURKA |
| 2.041e-03 | -6.19 | frontal_lobe | COSMIC cancer mutations | frontal_lobe | 74 | 16 | 17775 | 1757 |
SCN5A,NF2,AKT1,RET,TP53,IDH1,GNA11,CDKN2C,GNAS,FAT4,PTEN,FGFR2,PIK3CA,CDKN1B,SYK,DCBLD1 |
| 2.041e-03 | -6.19 | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | 36 | 10 | 17758 | 1761 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,NRG2,CDKN1B,NRG1,PHLPP1 |
| 2.041e-03 | -6.19 | HUANG_FOXA2_TARGETS_DN | MSigDB lists | HUANG_FOXA2_TARGETS_DN | 36 | 10 | 17758 | 1761 |
GAS2L1,IGFBP6,COL13A1,S100A4,PLAUR,COL6A1,CDH3,ACOX2,LOXL2,LEPR |
| 2.041e-03 | -6.19 | REACTOME_PI3K_AKT_ACTIVATION | MSigDB lists | REACTOME_PI3K_AKT_ACTIVATION | 36 | 10 | 17758 | 1761 |
IRS2,RHOA,AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,PHLPP1 |
| 2.041e-03 | -6.19 | ZHAN_MULTIPLE_MYELOMA_MF_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_DN | 36 | 10 | 17758 | 1761 |
ALDH2,TRANK1,RAPGEF2,CCDC110,CAMK1D,TMEM170B,RAD17,GLCCI1,ZNF275,DOCK9 |
| 2.041e-03 | -6.19 | ONGUSAHA_TP53_TARGETS | MSigDB lists | ONGUSAHA_TP53_TARGETS | 36 | 10 | 17758 | 1761 |
NQO1,PQLC3,SERPINE2,FXYD3,SAT1,TAP1,TP53,COL18A1,TOB1,FAS |
| 2.041e-03 | -6.19 | P_typ_ATPase | interpro domains | IPR001757 | 36 | 10 | 18293 | 1814 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.041e-03 | -6.19 | ATPase_P-typ_transduc_dom_A | interpro domains | IPR008250 | 36 | 10 | 18293 | 1814 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.041e-03 | -6.19 | ATPase_P-typ_P_site | interpro domains | IPR018303 | 36 | 10 | 18293 | 1814 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.041e-03 | -6.19 | V$CEBPB_02 | MSigDB lists | V$CEBPB_02 | 245 | 39 | 17758 | 1761 |
PLA2G4A,SPRED1,NCKAP5,BMF,MRC2,TTC39B,UGP2,THRA,PDCL,PDGFB,DENND2D,TMPRSS4,SIRPA,LMO4,RRBP1,STEAP2,BCL6,CDKN1B,GOT1,PDE4D,MAP3K3,SMARCA2,TGIF1,C6orf1,LONRF3,CITED4,MOSPD2,SERTAD4,RC3H2,ITPR3,PCTP,PITX2,NFKBIA,NFKBIZ,EFNA5,ARF6,PRR15,TOB1,HOXC13 |
| 2.041e-03 | -6.19 | V$LEF1_Q6 | MSigDB lists | V$LEF1_Q6 | 245 | 39 | 17758 | 1761 |
SORBS1,HOXB7,GABRG2,COL18A1,SDC1,TNFRSF19,SIX4,NRP2,FOXP2,WEE1,SESN3,IGF1R,SHC3,RGS3,BMP7,KLF3,ELF5,CLDN4,ABCD1,PDE4D,PIM1,TGIF1,ELK3,SERTAD4,SH3BGRL,TCF7,AIF1L,ZFAND5,RNF19B,STEAP1,CDK5R1,ABR,DPYSL3,BCAR3,HS6ST1,PTPRJ,CORO1C,NKD1,LIFR |
| 2.046e-03 | -6.19 | Nucl_hrmn_rcpt_lig-bd | interpro domains | IPR000536 | 48 | 12 | 18293 | 1814 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.053e-03 | -6.19 | V$IK1_01 | MSigDB lists | V$IK1_01 | 261 | 41 | 17758 | 1761 |
LTBP1,PACSIN2,ARAP3,IL13RA1,VARS2,PRKACA,CYP26A1,WWP2,IRF2BPL,CDKN2C,ZNF687,RNF128,SHC3,LHX6,ELF5,ABCA2,TFAP2A,VAT1,TRPC1,TWIST1,SEMA3G,CITED2,NCOA2,TNIP1,ATP1B1,SAV1,MRPS36,GNA11,SP4,ABR,COL12A1,ITPR1,NR4A3,FAM117A,SP6,HOXB13,WDR62,ARPC2,LIFR,NR3C2,COBL |
| 2.055e-03 | -6.19 | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | 175 | 30 | 17758 | 1761 |
PCGF5,LRRFIP2,IL15RA,PLSCR1,TRIP10,HAPLN3,PSME2,HLA-F,NUB1,TAP1,PPFIBP2,SAMD9,BLVRA,DUSP4,TMCC3,OPTN,DTX3L,SERPINA1,ITGB8,PVRL2,TRIM69,ZNF367,NMI,NLRC5,ETV7,JAK3,SCYL3,APOL2,APOBEC3G,TMEM131 |
| 2.055e-03 | -6.19 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | 175 | 30 | 17758 | 1761 |
GRN,ORAI2,COL9A3,SLC37A1,CD40,ALCAM,C11orf95,ATP10D,ADRBK2,TNS3,NCOA3,SWAP70,BANK1,METTL7A,PRCP,CORO1C,BHLHE41,PLCG2,SLC2A6,DTX4,OPN3,CLMN,TLE1,DHTKD1,TSPAN13,LRRK1,SYK,GM2A,SCN3A,FARP2 |
| 2.066e-03 | -6.18 | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | MSigDB lists | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | 459 | 65 | 17758 | 1761 |
HECA,TRIM2,EPHA4,CTDSPL,CACNA2D2,RNF182,MPP5,SNN,PHLDA1,GRM5,CPNE2,ACAP2,DPYSL2,OSBPL3,EPB41L4B,PDIA6,BTBD3,MAP3K3,CPD,SIRT1,THRB,PTPN9,ATP1B1,IRS2,TRIM9,PIAS3,HLF,RBM47,SLC9A6,CBX7,NR2C2,CPEB4,SCOC,TBC1D1,PBX3,CNTNAP2,ETS1,ANO1,LBR,IRF2BPL,E2F7,ITGB8,ADRBK1,ITGA3,CYR61,FAM13B,NPTXR,ATP2B1,NCOA2,TRAK2,PHF20L1,ZC3H11A,NR3C1,C2orf69,FNDC3A,FOS,KLHL2,TIMP3,RAB11FIP2,CSNK1G1,NR4A3,ZDHHC7,TBC1D4,COL16A1,RGMA |
| 2.068e-03 | -6.18 | S_TKc | smart domains | SM00220 | 268 | 45 | 9131 | 997 |
PRKAA2,CDK17,NUAK1,CIT,CAMKK1,RPS6KA1,GRK6,CAMK1D,PKN1,PRKACA,DAPK2,RPS6KA2,ADRBK1,CDK16,PASK,PLK4,SGK3,PRKG1,NEK2,DAPK1,SGK1,MAPK11,PIM1,MAST4,MAP3K3,PLK1,AKT1,PRKCQ,MAP3K6,STK17B,CDK1,ADRBK2,STK17A,MAPKAPK2,CDK19,STK26,STK38,PLK2,AURKA,STK39,CDK18,MAP3K5,HIPK3,MELK,MAPK12 |
| 2.072e-03 | -6.18 | NUCLEAR_REC_DBD_2 | prosite domains | PS51030 | 46 | 12 | 11866 | 1235 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.072e-03 | -6.18 | NUCLEAR_REC_DBD_1 | prosite domains | PS00031 | 46 | 12 | 11866 | 1235 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.080e-03 | -6.18 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 145 | 26 | 17758 | 1761 |
CDKN1C,IFITM3,HLA-E,TSC22D3,FXYD3,SAT1,NFE2L1,PSME1,F11R,SEPP1,CA2,CDH1,PTEN,CALD1,NFKBIA,BCL6,DAPK1,CD9,PIK3C2B,TACSTD2,GEM,MAP3K5,CITED2,CCNB2,CYBRD1,SEMA3B |
| 2.086e-03 | -6.17 | Ligand-independent caspase activation via DCC | REACTOME pathways | R-HSA-418889 | 10 | 5 | 8202 | 867 |
DAPK2,CASP3,UNC5B,CASP9,DAPK1 |
| 2.088e-03 | -6.17 | nucleotide binding | molecular function | GO:0000166 | 2291 | 272 | 16491 | 1673 |
ACACB,AK7,ATP8A1,RET,TAP1,DHX8,CAMK1D,DAPK2,WEE1,UBE2T,ALDH1A3,PIK3CA,AOX1,TUBG1,CRY2,PIK3CD,ACOX2,NWD1,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,TP53I3,POR,ARF4,ENPP1,RBM47,DNM1L,PLK2,LIMK1,ATP7B,NOD2,ITPKA,ARF6,DDX58,CDK17,NUAK1,DGKQ,RAB23,KIF23,MERTK,BMP2K,RAVER2,C9orf69,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAST4,DGKG,MCCC2,PRODH,KIF20A,ADCK3,PIP4K2C,EPHA1,ATP8B3,GNA11,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,NRBP1,TMEM173,XDH,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TESK2,GRK6,AIFM2,PRKACA,DDR1,TRANK1,PDE4D,EPHB4,ACSL4,RAB27B,ARL4D,MYO5B,MX1,RIPK2,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,JAK1,CDK19,STK26,AXL,SLC27A1,MLKL,SLC27A3,MAPK12,TNRC6C,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,DIRAS3,SLC27A6,FAM20B,SGK3,ATP8B1,MAPK11,ERBB3,OPLAH,RAPGEF2,UBE2A,AK4,YES1,KIF11,ACADSB,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,LRRK1,CENPE,CMPK2,CPEB2,MELK,NMRK1,CRYM,CAMKK1,EPHA4,VARS2,ABCD4,RAB15,RPS6KA2,PASK,PAPSS1,ABCA2,RAB20,RP2,MYH14,DDX59,NLRP4,PLK1,ATL1,ARFRP1,ROR1,IDH1,ADRBK2,STK17B,CDK1,RHEB,PIK3C2B,RRAGD,PRKAA2,LMTK3,RUNX2,BVES,PEX6,ABCG2,TEC,RAB6A,DHRS3,DAZAP1,UBE2Q2,IGF1R,KIF13B,AHCY,PIM1,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,MAPKAPK2,GNAS,NUDT16,PRPS2,NLRC5,ALPK3,RHOBTB2,JAK3,UPF3B,UGP2,TP53,ERBB2,MRAS,KIF14,SRR,PLK4,OAS3,SCYL3,SEPHS1,SIRT1,MAP3K3,CLCN3,AKT1,FIGNL1,MAP3K6,ATP13A2,ARHGAP35,DUOX1,ATP1A1,IDE,PTK7,STK38,PTBP3,AIFM3,ABCA1,PINK1,CPEB4,TOR4A,CIT,GNE,TGFBR1,TRIB2,TMEM63A,TOP2A,KIF5B,ADRBK1,CDK16,UBE2J1,GTF2F2,SGK1,ABCD1,BUB1,SYK,RBMS2,MYO5A,ATP2B1,RHOA,RAB3B,GCLC,NADK2,RUNX3,DGKE,SWAP70,RND3,HNRNPH2,RAP2C,GEM,UBE2C,HIPK3,ZBTB33,ABCG1 |
| 2.093e-03 | -6.17 | WIERENGA_STAT5A_TARGETS_GROUP1 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP1 | 123 | 23 | 17758 | 1761 |
CDKN1C,CALB2,TGFBR1,CTSZ,FBXO6,DHRS3,TP53INP2,PHLDA1,STK17B,NCS1,SLC9A7,SNTA1,SLC25A4,GATA2,VASN,A4GALT,P4HA2,DAPK1,SH3BP4,PIM1,RASGEF1A,RAP1GAP,F2RL1 |
| 2.093e-03 | -6.17 | ENZYME_ACTIVATOR_ACTIVITY | MSigDB lists | ENZYME_ACTIVATOR_ACTIVITY | 123 | 23 | 17758 | 1761 |
DOCK4,ARAP3,RAPGEF2,RALBP1,RASA2,CASP9,RGS20,ARFGEF1,PRKRA,RASA1,ABR,CDK5R1,ARHGEF10L,MMP15,CARD8,RGS3,MMP17,MADD,CTSA,MAP3K5,RGS14,RAP1GAP,AIFM3 |
| 2.093e-03 | -6.17 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | 123 | 23 | 17758 | 1761 |
GRN,PLK1,LGALS3,S100A11,IQGAP1,S100A4,TAP1,LITAF,CYB561,PDK3,SPTLC2,SNX12,STX3,SIRPA,CYP26A1,TAPBP,NCOA3,CTSC,NFKBIZ,ATP1B3,LGMN,SNX10,S100A6 |
| 2.093e-03 | -6.17 | embryonic limb morphogenesis | biological process | GO:0030326 | 127 | 24 | 16441 | 1675 |
CYP26B1,RUNX2,GRHL2,SALL4,LRP4,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,IMPAD1,MEGF8,HOXA9,FRAS1,BMP7,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,RARG |
| 2.093e-03 | -6.17 | embryonic appendage morphogenesis | biological process | GO:0035113 | 127 | 24 | 16441 | 1675 |
CYP26B1,RUNX2,GRHL2,SALL4,LRP4,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,IMPAD1,MEGF8,HOXA9,FRAS1,BMP7,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,RARG |
| 2.094e-03 | -6.17 | negative regulation of Ras protein signal transduction | biological process | GO:0046580 | 41 | 11 | 16441 | 1675 |
ARHGAP24,TIMP2,ARAP3,ITGA3,RASA2,BCL6,STMN3,DAB2IP,SPRY2,RASA1,ARHGAP35 |
| 2.105e-03 | -6.16 | MODULE_94 | MSigDB lists | MODULE_94 | 359 | 53 | 17758 | 1761 |
EXPH5,ACACB,GCLM,PACSIN2,NKX3-1,IL15RA,CDH22,HOXB7,ARHGEF11,EPS8,ARL4C,GABRG2,IL27RA,CNTNAP2,SEPP1,PPP2R3A,CHPF,IER3,NOV,CARD8,CABP1,RIMS3,DAPK1,TPST1,CDKN1B,MTMR11,ACSL4,PTPRE,RASGRP1,FARP2,HES1,PLEKHA6,PCDH1,GRIN1,CR2,SLC11A2,PRKCQ,COL7A1,ROR1,F12,DUSP4,MFSD7,STEAP1,GPRC5B,SCG2,ATP7B,CSTF2,NR4A2,SERPINI1,HOXB13,ITPKA,TMEM159,F2RL1 |
| 2.107e-03 | -6.16 | pituitary-adenoma | COSMIC cancer mutations | pituitary-adenoma | 15 | 6 | 17775 | 1757 |
GNAS,CDKN2C,AKT1,IDH1,PIK3CA,TP53 |
| 2.107e-03 | -6.16 | meninges-meningioma-anaplastic | COSMIC cancer mutations | meninges-meningioma-anaplastic | 15 | 6 | 17775 | 1757 |
CDKN2C,NF2,AKT1,IDH1,PTEN,PIK3CA |
| 2.107e-03 | -6.16 | meninges-meningioma-atypical | COSMIC cancer mutations | meninges-meningioma-atypical | 15 | 6 | 17775 | 1757 |
CDKN2C,NF2,AKT1,IDH1,PTEN,PIK3CA |
| 2.107e-03 | -6.16 | tibia | COSMIC cancer mutations | tibia | 871 | 112 | 17775 | 1757 |
ILDR1,NCKAP5,FOXM1,FAM199X,RALBP1,RET,NDC80,TP53,COL18A1,ERBB2,NDRG2,GRK6,TMEM170B,CA8,AIFM2,DENND2D,TNFSF9,EPS8L2,SYTL2,NKAIN3,APLP2,CTGF,KIAA1107,TRANK1,STIM1,ZFP36,PRICKLE3,REEP1,PIK3CA,FUT1,CNNM4,TMEM64,PIK3CD,ANO4,EGLN3,NEB,DVL2,CLCN3,AKT1,FIGNL1,UTRN,TNS1,SAV1,ANLN,IDH1,SESN1,COL12A1,PLCH1,PTPRJ,DDOST,ANKRD6,WIPI1,ATP7B,GNPTAB,PLEKHG1,PRKCDBP,ARRDC1,SPTBN5,NR2C2,ZMAT1,SCN5A,PPP1R2,LRRFIP2,FAM169A,CD109,IGF1R,ALPP,LLGL2,FRAS1,KIF13B,BMP7,MEGF8,RRBP1,BDH1,PRKG1,MAP3K9,FAM102A,FAR2,ZMYM1,TPCN1,CCDC88A,MYO5A,GPR161,PARP9,EPB41L5,SUN2,MFI2,NR4A1,MRS2,PPARA,GYLTL1B,DIAPH2,YES1,RNPEP,NFIB,MUM1L1,GNAS,TRIM69,ACVRL1,NR1D2,ITPR1,NLRC5,RHOBTB2,FHL1,ZDBF2,ITGAV,PLOD3,WDR62,ESPL1,ARHGEF4,EHD1,SNPH |
| 2.108e-03 | -6.16 | soft_tissue-striated_muscle-rhabdomyosarcoma-sclerosing | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-sclerosing | 61 | 14 | 17775 | 1757 |
GNAS,ARAP3,AKT1,FGFR2,ITGA7,RET,PIK3R1,TMEM143,PIK3CA,TP53,ERBB2,IDH1,GNA11,FRMD4B |
| 2.109e-03 | -6.16 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | 74 | 16 | 17758 | 1761 |
CCNE2,CDA,AK4,MGST2,CCNB1,CDK1,PDGFA,CDH1,NFKBIA,MAP3K9,HDAC1,IRF7,TNFRSF12A,ERBB3,CCNB2,CTH |
| 2.115e-03 | -6.16 | REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | REGULATION_OF_MOLECULAR_FUNCTION | 318 | 48 | 17758 | 1761 |
CCNE2,SIGIRR,SPRED1,CDKN1C,RALBP1,TP53,ERBB2,HERC5,PKN1,TRIB2,CARD10,CCND1,CDKN2C,DIRAS3,CARD8,PTEN,RGS3,MAP3K9,BAX,SERINC2,MDFIC,F2R,PLCB2,CDKN2D,CCDC88A,CKS2,MDFI,CASP9,STRADB,PRKCQ,PIF1,PKMYT1,MAP3K6,CDK5R1,EDNRA,GNAS,CDK5RAP1,RBL1,MADD,NOD2,FGD6,GLA,MAP3K5,AIFM3,IFI6,HIPK3,FGD1,EGLN1 |
| 2.121e-03 | -6.16 | plasma membrane raft | cellular component | GO:0044853 | 87 | 18 | 17570 | 1756 |
SPRED1,SCN5A,PACSIN2,LRP4,EZR,ATP1B1,HDAC6,PRKACA,EMP2,ATP1A1,CDH1,IGF1R,CORO1C,PRKCDBP,SLC27A1,EFNA5,ATP1B3,F2R |
| 2.121e-03 | -6.16 | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | 183 | 31 | 17758 | 1761 |
PLSCR1,PSME2,HEBP1,USP18,CNOT8,FAM134A,TAP1,ERI2,FBXO6,IFIT3,NTAN1,HERC6,SLC25A43,BMP2K,RHEB,SCARB2,CTSC,TRIM69,SETD3,NMI,SECTM1,SGK3,AURKA,PPP2R3C,HYLS1,CYP2U1,FAR2,CMPK2,IFIH1,PARP9,LAMP3 |
| 2.121e-03 | -6.16 | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | 183 | 31 | 17758 | 1761 |
MX1,TRIM8,PARP12,GUSB,HERC5,SLC11A2,KIF13A,FBXO6,PHLPP1,SNN,IFIT3,NTAN1,HERC6,MERTK,HMGXB4,MAN2A2,SCARB2,TNS3,FAM46A,ELMO2,C19orf66,RIMS3,CCDC69,FGD6,ZDHHC7,PITPNA,OAS3,ZMIZ1,CMPK2,CLIP2,CKAP4 |
| 2.121e-03 | -6.16 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | 183 | 31 | 17758 | 1761 |
TGIF1,LASP1,TM2D2,MFI2,LONRF3,LGALS3,CD63,GNPDA1,UBASH3B,PLEKHO1,HEXB,SERTAD3,TGFBR1,S100A2,LHFPL2,SNX12,BCAP31,STX3,BCAR3,SCARB2,SLCO4A1,PPP2R5A,EFR3A,LIMK1,CORO1C,ADCK2,SGK1,BRI3,NRBP1,WBP5,RRAGD |
| 2.121e-03 | -6.16 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | 183 | 31 | 17758 | 1761 |
RASGRF1,MRC2,LONRF3,GGA1,CORO2A,ZCCHC24,CIT,HABP4,ARL4C,NCKAP1,HES2,ANTXR1,STIL,ANO1,ARHGEF26,SH2D4A,SOX13,FECH,PSMD1,ANKS1B,CYP4F11,FRAS1,AMMECR1,TMC5,BMP1,ARRB1,NPTXR,NCAPG2,ZNF365,LIFR,RUSC1 |
| 2.126e-03 | -6.15 | WANG_BARRETTS_ESOPHAGUS_DN | MSigDB lists | WANG_BARRETTS_ESOPHAGUS_DN | 25 | 8 | 17758 | 1761 |
PRCP,OVOL1,KLK7,KLK6,KLF5,EMP2,SERPINB1,LTA4H |
| 2.126e-03 | -6.15 | KINASE_INHIBITOR_ACTIVITY | MSigDB lists | KINASE_INHIBITOR_ACTIVITY | 25 | 8 | 17758 | 1761 |
CDKN2C,CDKN1C,DNAJC3,CDKN1B,CDKN2D,PKIA,MAPK8IP1,SOCS3 |
| 2.126e-03 | -6.15 | EXTRINSIC_TO_MEMBRANE | MSigDB lists | EXTRINSIC_TO_MEMBRANE | 25 | 8 | 17758 | 1761 |
GNAS,MUC16,PLAUR,ARRB1,EZR,SYTL4,APC2,SYTL2 |
| 2.126e-03 | -6.15 | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY | MSigDB lists | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY | 25 | 8 | 17758 | 1761 |
THRB,NR3C1,THRA,NR4A3,RARG,AHR,NR2C1,NR3C2 |
| 2.132e-03 | -6.15 | negative regulation of epithelial cell proliferation | biological process | GO:0050680 | 113 | 22 | 16441 | 1675 |
NKX3-1,CDKN1C,SOX9,RGCC,TGFBR1,RUNX3,VASH1,SAV1,NFIB,CD109,FGFR2,PTEN,SCG2,ACVRL1,CTSV,PEX2,DLG1,CDKN1B,DAB2IP,KLF9,ETV4,XDH |
| 2.134e-03 | -6.15 | PRKCA (protein kinase C, alpha) | protein interactions | 5578 | 249 | 42 | 16036 | 1726 |
DDX58,RALBP1,SDC4,HABP4,TP53,GABRG2,SELL,F11R,HDAC6,HLA-A,LMNA,GRM5,TOP2A,APLP2,ADD3,ADRBK1,PLCG2,PRKG1,CD9,TIAM1,SYK,DVL2,ATP2B1,GFPT1,HES1,MBP,RHOA,PSMB4,PPARA,GRIN1,EZR,SCRIB,FAS,ATP1A1,NFKBIA,KLF5,PLD1,HMGA1,ITPKA,NRGN,AFAP1,OCLN |
| 2.139e-03 | -6.15 | nucleoside phosphate binding | molecular function | GO:1901265 | 2292 | 272 | 16491 | 1673 |
ACACB,AK7,ATP8A1,RET,TAP1,DHX8,CAMK1D,DAPK2,WEE1,UBE2T,ALDH1A3,PIK3CA,AOX1,TUBG1,CRY2,PIK3CD,ACOX2,NWD1,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,TP53I3,POR,ARF4,ENPP1,RBM47,DNM1L,PLK2,LIMK1,ATP7B,NOD2,ITPKA,ARF6,DDX58,CDK17,NUAK1,DGKQ,RAB23,KIF23,MERTK,BMP2K,RAVER2,C9orf69,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAST4,DGKG,MCCC2,PRODH,KIF20A,ADCK3,PIP4K2C,EPHA1,ATP8B3,GNA11,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,NRBP1,TMEM173,XDH,EHD1,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,TESK2,GRK6,AIFM2,PRKACA,DDR1,TRANK1,PDE4D,EPHB4,ACSL4,RAB27B,ARL4D,MYO5B,MX1,RIPK2,SEPT6,PANK1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,JAK1,CDK19,STK26,AXL,SLC27A1,MLKL,SLC27A3,MAPK12,TNRC6C,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,DIRAS3,SLC27A6,FAM20B,SGK3,ATP8B1,MAPK11,ERBB3,OPLAH,RAPGEF2,UBE2A,AK4,YES1,KIF11,ACADSB,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,LRRK1,CENPE,CMPK2,CPEB2,MELK,NMRK1,CRYM,CAMKK1,EPHA4,VARS2,ABCD4,RAB15,RPS6KA2,PASK,PAPSS1,ABCA2,RAB20,RP2,MYH14,DDX59,NLRP4,PLK1,ATL1,ARFRP1,ROR1,IDH1,ADRBK2,STK17B,CDK1,RHEB,PIK3C2B,RRAGD,PRKAA2,LMTK3,RUNX2,BVES,PEX6,ABCG2,TEC,RAB6A,DHRS3,DAZAP1,UBE2Q2,IGF1R,KIF13B,AHCY,PIM1,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,MAPKAPK2,GNAS,NUDT16,PRPS2,NLRC5,ALPK3,RHOBTB2,JAK3,UPF3B,UGP2,TP53,ERBB2,MRAS,KIF14,SRR,PLK4,OAS3,SCYL3,SEPHS1,SIRT1,MAP3K3,CLCN3,AKT1,FIGNL1,MAP3K6,ATP13A2,ARHGAP35,DUOX1,ATP1A1,IDE,PTK7,STK38,PTBP3,AIFM3,ABCA1,PINK1,CPEB4,TOR4A,CIT,GNE,TGFBR1,TRIB2,TMEM63A,TOP2A,KIF5B,ADRBK1,CDK16,UBE2J1,GTF2F2,SGK1,ABCD1,BUB1,SYK,RBMS2,MYO5A,ATP2B1,RHOA,RAB3B,GCLC,NADK2,RUNX3,DGKE,SWAP70,RND3,HNRNPH2,RAP2C,GEM,UBE2C,HIPK3,ZBTB33,ABCG1 |
| 2.143e-03 | -6.15 | SINGH_NFE2L2_TARGETS | MSigDB lists | SINGH_NFE2L2_TARGETS | 15 | 6 | 17758 | 1761 |
GCLM,TXN,GRK6,NQO1,GCLC,ABCC1 |
| 2.143e-03 | -6.15 | MODULE_519 | MSigDB lists | MODULE_519 | 15 | 6 | 17758 | 1761 |
PDIA3,ALDH7A1,IDH1,ERP29,PDIA4,PDIA5 |
| 2.143e-03 | -6.15 | ACTIVATION_OF_JNK_ACTIVITY | MSigDB lists | ACTIVATION_OF_JNK_ACTIVITY | 15 | 6 | 17758 | 1761 |
MDFIC,MAP3K5,PKN1,MAP3K6,MDFI,MAP3K9 |
| 2.143e-03 | -6.15 | ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN | MSigDB lists | ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN | 15 | 6 | 17758 | 1761 |
MORF4L2,CCNB1,GAB1,IL6ST,EPS8L2,PARP9 |
| 2.143e-03 | -6.15 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | MSigDB lists | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | 15 | 6 | 17758 | 1761 |
PLK1,WEE1,PKMYT1,CCNB1,CCNB2,CDK1 |
| 2.143e-03 | -6.15 | BIOCARTA_AKAPCENTROSOME_PATHWAY | MSigDB lists | BIOCARTA_AKAPCENTROSOME_PATHWAY | 15 | 6 | 17758 | 1761 |
PRKAR2B,RHOA,PKN1,MAP2,CDK1,NUP85 |
| 2.151e-03 | -6.14 | basement membrane | cellular component | GO:0005604 | 94 | 19 | 17570 | 1756 |
TIMP2,HSPG2,ITGA6,P3H2,COL18A1,VWA1,COL7A1,COL4A5,LOXL2,ERBB2IP,FBLN1,DAG1,TIMP3,NPNT,FRAS1,CST3,MATN2,DLG1,NTN4 |
| 2.152e-03 | -6.14 | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | MSigDB lists | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | 222 | 36 | 17758 | 1761 |
ADD1,CENPI,ARL4C,ABCG2,PHLDA1,H1FX,IER3,BTG3,NOV,PQLC2,ZFP36,FOSB,TFAP2A,SGK1,KLF9,GAD1,SLC12A2,TIPARP,SPRY2,CYP1B1,GCLC,PTGER4,FOS,CDK5R1,FZD7,CD83,ETS2,PLK2,NFKBIA,RAB11FIP1,FAM117A,PIK3C2B,NR4A2,HOOK1,MAFF,EHD1 |
| 2.154e-03 | -6.14 | regulation of lymphocyte proliferation | biological process | GO:0050670 | 186 | 32 | 16441 | 1675 |
CASP3,LGALS3,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,ICOSLG,JAK3,NDFIP1,AHR |
| 2.154e-03 | -6.14 | PTGFRN (prostaglandin F2 receptor inhibitor) | protein interactions | 5738 | 14 | 6 | 16036 | 1726 |
FBXO6,LGALS3,CD63,A4GALT,CD82,CD9 |
| 2.154e-03 | -6.14 | TGFB3 (transforming growth factor beta 3) | protein interactions | 7043 | 14 | 6 | 16036 | 1726 |
TGFBR1,CTGF,ACVRL1,VASN,LTBP3,SDC4 |
| 2.169e-03 | -6.13 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 138 | 25 | 17758 | 1761 |
TGIF1,ENO2,FRMD6,RUSC2,SDC4,SAT1,PTGER4,VWA1,IL13RA1,DUSP4,ETS1,MERTK,PHLDA1,FOS,PGF,ACAP2,CTGF,CYR61,PLK2,ZFP36,NFKBIA,SGK1,PRKCDBP,NFKBIZ,SPRY2 |
| 2.172e-03 | -6.13 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | 168 | 29 | 17758 | 1761 |
DDX58,MX1,LOC81691,TGIF1,ARAP2,IL15RA,IL15,HAPLN3,TAP1,BTN3A1,SAMD9,HERC6,TMCC3,FAS,PLS3,DGKH,DTX3L,FAM111A,HPSE,C19orf66,FGFR2,TRIM69,SECTM1,PLEKHF1,IRF7,HS3ST3B1,GLCCI1,IFIH1,APOBEC3G |
| 2.178e-03 | -6.13 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | 191 | 32 | 17758 | 1761 |
LAMP1,LASP1,ACTR8,DCAF7,PDCL,BARD1,TIPRL,VPS26A,ZFYVE16,PHTF1,PLCG2,FAM13B,FAIM,NCAM1,PTPRE,APOBEC3G,ENPP4,CPD,ARAP2,STAU2,ITCH,ASPM,YES1,GALNT7,PCTP,IDH1,ATP10D,GALNT3,UTP14C,STK39,SLC27A3,TRAF5 |
| 2.178e-03 | -6.13 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | 191 | 32 | 17758 | 1761 |
NFKBIE,BLVRB,PPFIBP2,TDRKH,C3orf18,BCAP31,LMNA,GNS,APLP2,C7orf49,METTL7A,DACT1,AHCY,TINAGL1,NAGA,FAM69A,LAMP2,MMD,GUSB,NUSAP1,RAB38,BLVRA,NPC2,DAG1,CD83,SPINT2,NR4A3,ARRB1,KLF11,ADIPOR1,GLA,ZMIZ1 |
| 2.178e-03 | -6.13 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | 191 | 32 | 17758 | 1761 |
ENO2,GALNT12,ITGA6,TRIB2,NUCB2,C11orf95,ETS1,IL18R1,DENND2D,LTBP3,MGAT4A,PASK,FAM102A,MYBL1,COL6A2,SYNE2,PRKCQ,RUNX3,YES1,ITPR3,PRIM1,PLCG1,ALDH5A1,LRIG1,AMMECR1,INPP4B,SERPINI1,FHL1,TRAF5,TBC1D4,NR3C2,DOCK9 |
| 2.178e-03 | -6.13 | GSE3982_MAC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_MAC_VS_BASOPHIL_UP | 191 | 32 | 17758 | 1761 |
PLA2G4A,ARMCX3,CAST,CD82,CALB2,ETV5,RET,ERI2,ASAH1,TGFBR1,ERP29,PPP2R3A,SCML1,DOPEY2,IMPAD1,IL6ST,GLB1L2,DIXDC1,MYO5A,CKS2,PPIF,GFPT1,ENPP4,FADS2,B3GNT2,TESK1,RC3H2,RNPEP,IDH1,GNA11,DDOST,PGRMC1 |
| 2.178e-03 | -6.13 | GSE22886_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_TCELL_VS_BCELL_NAIVE_UP | 191 | 32 | 17758 | 1761 |
SIGIRR,ENO2,ITGA6,ARL4C,BTN3A1,IL27RA,NUCB2,M6PR,PSMD1,TBCD,SORL1,FAM102A,WWP1,TECR,CITED2,PPP6R1,IFITM3,HMG20B,PRKCQ,ATP13A2,PLCG1,MSL1,ATP1A1,NGFRAP1,SEMA4D,INPP4B,CABIN1,NDFIP1,TOB1,NRBP1,DEF6,DOCK9 |
| 2.178e-03 | -6.13 | GSE17721_12H_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDM_UP | 191 | 32 | 17758 | 1761 |
CASP3,TTC39B,SERPINE2,IL15,HEBP1,INTS8,SLC1A3,FBXO6,FAM46C,PARM1,CDKN2C,BHLHE41,ZFP36,MITF,ECE1,ETV4,SUN2,PIK3R1,PTGER4,EZR,PKMYT1,ASB13,CD40,FAS,ENDOD1,CARHSP1,AP1AR,PPP2R5A,PVRL2,SEMA3A,IFIH1,PTGES |
| 2.178e-03 | -6.13 | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | 191 | 32 | 17758 | 1761 |
ARAP3,BTN3A1,EFHD2,SAMD9,HDAC9,TRANK1,CTGF,CYP4F11,FAM63A,BCL6,AOX1,ADAM15,ABCD1,PIM1,ETV7,CDKN2D,CTDSP2,XKR8,TRIM8,MBP,SYNE2,DOCK5,PRCP,HNRNPH2,TMC5,DHTKD1,ZNF165,CABIN1,ADIPOR1,F2RL1,IFIH1,HOOK1 |
| 2.183e-03 | -6.13 | negative regulation of cell differentiation | biological process | GO:0045596 | 590 | 82 | 16441 | 1675 |
GAS2L1,GRHL2,INPP5D,EPHA4,TP53,PKP2,ERBB2,IL18,FAM101B,CCND1,NOV,ELF5,BCL6,DUSP10,DAB2IP,TWIST1,TACSTD2,DIXDC1,SEMA3G,NOTCH3,SEMA3B,SIRT1,FZD7,DPYSL3,ENPP1,PLK2,CORO1C,HOXA9,INPP4B,HDAC1,NRG1,ARF6,ABCA1,SEMA6B,SORT1,ADGRG1,UBASH3B,CIT,SOX9,LRP4,TGFBR1,TRIB2,FBLN1,SIX4,PTEN,GATA2,BMP7,BHLHE41,VASN,KIAA0319,SORL1,WNT3A,TRIM62,SOCS5,HES1,RHOA,MFI2,RAPGEF2,ASPM,PIK3R1,MBNL3,PPARA,PRICKLE1,NPHP3,CDK5R1,NCOA3,AP1AR,ACVRL1,SEMA4D,TWSG1,NFKBIA,ITGAV,GDF11,GPER1,OSR1,SOX8,SEMA3A,JAK3,TOB1,RARG,ABCG1,XDH |
| 2.183e-03 | -6.13 | CH | prosite domains | PS50021 | 71 | 16 | 11866 | 1235 |
LMO7,GAS2L1,SPEF2,ASPM,IQGAP1,SYNE2,UTRN,SPTB,PLS3,SMTNL2,CLMN,LIMCH1,DIXDC1,SPTBN5,TAGLN2,IQGAP3 |
| 2.196e-03 | -6.12 | INTRACELLULAR_TRANSPORT | MSigDB lists | INTRACELLULAR_TRANSPORT | 278 | 43 | 17758 | 1761 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,BCL2L1,BARD1,ERP29,ZFYVE9,APPBP2,M6PR,ATG4A,KIF5B,ZFYVE16,DOPEY2,AP1M2,CDH1,KIF13B,STEAP2,ABCA2,BCL6,TINAGL1,LMAN1,F2R,TRAM1,KDELR1,MDFI,ATG4D,AKT1,COG2,STRADB,HTATIP2,KIF1C,NPC2,ICMT,OPTN,KLHL2,CTSA,LTBP2,ARSB,NRBP1,ABCA1,ABCG1 |
| 2.200e-03 | -6.12 | V$OCT_C | MSigDB lists | V$OCT_C | 246 | 39 | 17758 | 1761 |
SCOC,THRA,TSC22D3,MRAS,DSE,TEAD3,PPP2R3A,HDAC9,SESN3,ADORA1,PTEN,CYR61,DPYSL2,LHX6,CNNM4,TSPAN13,MANF,PDE4D,DGKG,WBP5,PLEKHA6,ING1,FZD4,SH3BGRL,SERTAD4,STAT4,KIF13A,LDB2,ITPR3,DPYSL3,FGFR2,MMP17,FAM117A,TMOD2,SP6,PPP2R3C,JARID2,NXT2,TLL2 |
| 2.209e-03 | -6.12 | phosphatidylinositol 3-kinase binding | molecular function | GO:0043548 | 30 | 9 | 16491 | 1673 |
IRS2,CALM2,ATP1A1,IGF1R,PIK3AP1,CALM1,PIK3R1,CALM3,DAB2IP |
| 2.214e-03 | -6.11 | MARTINEZ_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_TP53_TARGETS_UP | 580 | 79 | 17758 | 1761 |
LTBP1,SLC2A4,SORBS1,ADD1,SLC25A13,PTTG1,OSR2,DDR1,EMP2,BCAP31,SH3KBP1,IER3,PDGFA,WEE1,NOV,IL6ST,KLF3,CTTN,MARCH2,LMAN1,CTDSP2,MYO5B,CPD,CAPN6,PBK,ACO1,SLC11A2,GLO1,DPYSL3,IDE,JAK1,HOXA9,BMP1,LASP1,SORT1,PINK1,MRC2,CDKN1C,SCOC,KLHL13,ERI2,COL4A5,FAM21C,FBLN1,TNFRSF19,HOXB2,SIRPA,SGPL1,ADD3,FUT2,CYR61,DRAM1,FAH,FADS2,PDGFC,KIF20A,ZC3H11A,NR3C1,NR4A1,LITAF,TCF7,AIF1L,FOS,KIF11,NUBP1,TP53INP2,RANBP9,GNAS,FECH,PTPRF,PITX2,FUCA1,TWSG1,FGFR2,ITGAV,PLD1,SERPINB1,HIPK3,AHR |
| 2.216e-03 | -6.11 | dermatofibrosarcoma_protuberans | COSMIC cancer mutations | dermatofibrosarcoma_protuberans | 20 | 7 | 17775 | 1757 |
SS18,ACAP2,IDH1,PTEN,CARD10,ZFYVE9,PAQR7 |
| 2.216e-03 | -6.11 | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | 20 | 7 | 17775 | 1757 |
SS18,ACAP2,IDH1,PTEN,CARD10,ZFYVE9,PAQR7 |
| 2.223e-03 | -6.11 | SANA_TNF_SIGNALING_DN | MSigDB lists | SANA_TNF_SIGNALING_DN | 88 | 18 | 17758 | 1761 |
NQO1,EPAS1,ITGA6,KCTD12,ARHGDIB,FAM198B,LDB2,DDR1,ANTXR1,PCTP,PHLDA1,NFIB,GLCE,CTGF,CDCA7L,NTN4,ATP1B3,C1orf43 |
| 2.223e-03 | -6.11 | ZHANG_TLX_TARGETS_UP | MSigDB lists | ZHANG_TLX_TARGETS_UP | 88 | 18 | 17758 | 1761 |
HMMR,SHMT1,FIGNL1,ANLN,KIF11,CENPN,HMGXB4,FANCI,PRIM1,TOP2A,FAM111A,SLC4A4,RBL1,PLK4,BUB1,NCAPG2,SLC12A2,NUP85 |
| 2.227e-03 | -6.11 | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | 199 | 33 | 17758 | 1761 |
TXN,S100A11,AASS,SOX9,NRP2,IER3,ATG4A,TYMP,CDH1,LYPD3,ANKRD12,MANF,RASGRP1,CKAP4,MCCC2,SEC61B,TNIP1,SNTB2,LITAF,AK4,RUNX3,RNF19B,LHFPL2,CYB5A,CD83,TAPBP,SCARB2,FGFR2,WIPI1,NFKBIA,NR4A3,COBL,IFI6 |
| 2.229e-03 | -6.11 | regulation of cell cycle process | biological process | GO:0010564 | 540 | 76 | 16441 | 1675 |
DLGAP5,FOXM1,CAST,PSME2,CUL4B,CTDSPL,PTTG1,TP53,PSME1,CCNB1,PRKACA,PDGFB,STIL,FANCI,IER3,CALM2,SUSD2,CCND1,CYP1A1,PSMD1,RPS6KA2,CTGF,DACT1,KIF14,PLK4,CDKN1B,DAB2IP,CTDSP2,PLK1,AKT1,CDC20,PRKCQ,NUSAP1,PKMYT1,CCNF,ANLN,CDK1,JADE1,PLK2,OVOL1,E2F8,BIN1,CIT,SOX9,PSMD10,KIF23,CALM3,TFAP4,E2F7,IGF1R,PTEN,BMP7,NEK2,BUB1,PIM1,RHOA,PSMB4,CALM1,RGCC,BORA,KIF11,NUBP1,PSMA4,CDK5R1,NUDT16,TJP3,FGFR2,CDCA5,FAM83D,AURKA,FHL1,CENPE,GPER1,UBE2C,ESPL1,PKIA |
| 2.235e-03 | -6.10 | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | 95 | 19 | 17758 | 1761 |
SLC25A24,ARMCX3,PLSCR1,IFITM3,STAT4,FAM46C,ALCAM,IL18R1,EPCAM,B3GALNT1,WIPI1,OSBPL3,CD9,GRAMD1C,PLIN3,F2R,HOOK1,F2RL1,XDH |
| 2.248e-03 | -6.10 | ENZYME_BINDING | MSigDB lists | ENZYME_BINDING | 176 | 30 | 17758 | 1761 |
DOCK4,GCLM,EPAS1,RALBP1,PLAUR,PIK3R1,PARP4,TP53,NPC2,HDAC6,CD40,BCAR1,ADAMTSL4,RANBP9,RASA1,MAPK8IP1,TOP2A,CDKN2C,IGF1R,KIF13B,NFKBIA,RANBP1,DLG1,NOD2,FGD6,HDAC1,CDKN2D,ABCA1,CCDC88A,FGD1 |
| 2.258e-03 | -6.09 | WALLACE_PROSTATE_CANCER_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_UP | 20 | 7 | 17758 | 1761 |
PRSS8,GDF15,AHCY,UAP1,ST14,DAP,BDH1 |
| 2.258e-03 | -6.09 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | MSigDB lists | PID_ECADHERIN_KERATINOCYTE_PATHWAY | 20 | 7 | 17758 | 1761 |
PLCG1,RHOA,AKT1,CDH1,FMN1,PIK3R1,PIK3CA |
| 2.258e-03 | -6.09 | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | 20 | 7 | 17758 | 1761 |
TIPARP,GATA2,NR4A1,MAFF,PTGES,FOSB,IER3 |
| 2.263e-03 | -6.09 | ER-Phagosome pathway | REACTOME pathways | R-HSA-1236974 | 64 | 15 | 8202 | 867 |
HLA-B,TAPBP,PSMD1,SEC61B,PSMB4,PSME2,HLA-E,HLA-F,TAP1,PSMD10,PDIA3,PSME1,HLA-C,PSMA4,HLA-A |
| 2.274e-03 | -6.09 | PON2 (paraoxonase 2) | protein interactions | 5445 | 69 | 16 | 16036 | 1726 |
UGT8,B3GNT2,RHOA,ITGA6,CACNA2D2,FBXO6,ARSK,M6PR,ENPP1,IMPAD1,TMEM30A,LRIG1,ABCA2,NETO2,LRP11,SULF2 |
| 2.275e-03 | -6.09 | regulation of response to reactive oxygen species | biological process | GO:1901031 | 30 | 9 | 16441 | 1675 |
SESN3,TXN,PINK1,FBLN5,STK26,BMP7,NR4A3,HDAC6,SESN1 |
| 2.291e-03 | -6.08 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 161 | 28 | 17758 | 1761 |
AMOTL2,CD63,INPP5D,KIF1C,STIL,NFIB,DAG1,FZD7,LMNA,PLS3,CCND1,DAZAP1,CNTRL,CDK16,CALD1,PLK2,FAM114A1,SH3BP4,TCEAL4,TNFRSF12A,ALDH7A1,CTTN,ITGAV,S100A13,PPP6R1,CRTAP,DEF6,ZBTB33 |
| 2.293e-03 | -6.08 | p53 signaling pathway | KEGG pathways | hsa04115 | 68 | 16 | 6908 | 758 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,CDK1,TP53I3,FAS,CCND1,SESN3,PTEN,BAX,CCNB2 |
| 2.293e-03 | -6.08 | p53 signaling pathway | KEGG pathways | ko04115 | 68 | 16 | 6908 | 758 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,CDK1,TP53I3,FAS,CCND1,SESN3,PTEN,BAX,CCNB2 |
| 2.312e-03 | -6.07 | energy reserve metabolic process | biological process | GO:0006112 | 157 | 28 | 16441 | 1675 |
PRKAA2,GFPT1,ACACB,GAA,PGM1,PPP1R2,UGP2,AKT1,IQGAP1,CALM1,CACNA2D2,CALM3,PRKAR2B,ITPR2,ITPR3,SLC25A5,PRKACA,LEPR,GNAS,CALM2,PRKAG2,SLC25A4,IL6ST,ITPR1,KCNS3,PGM2L1,CACNA1D,PHKA2 |
| 2.314e-03 | -6.07 | RPS14_DN.V1_UP | MSigDB lists | RPS14_DN.V1_UP | 184 | 31 | 17758 | 1761 |
MX1,ANXA3,ARHGEF3,SDC4,ARL4C,PTGER4,KCTD12,GDF15,CACNB4,KBTBD11,ALCAM,SESN1,STX3,SIRPA,EPS8L2,FUCA1,PDGFA,RBM47,FRY,GNB5,PLK2,NR4A3,BCL6,CD9,ATP8B1,SORL1,MDFIC,PDE4D,PTPRE,SCN3A,CYP1B1 |
| 2.314e-03 | -6.07 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 184 | 31 | 17758 | 1761 |
MAN2B2,TGIF1,PDGFC,SLC35D2,ZNF395,ST14,ADCK3,HEBP1,HERC5,PSME1,NPC2,EPHA1,IFIT3,H1FX,STK17A,CCDC92,TAPBP,TRANK1,RAB11FIP2,GALNS,SPINT2,IRF7,KLF9,OAS3,PHKA2,TIAM1,IFI6,PPP2R2D,CKAP4,SMAGP,PCSK5 |
| 2.314e-03 | -6.07 | ESC_V6.5_UP_LATE.V1_UP | MSigDB lists | ESC_V6.5_UP_LATE.V1_UP | 184 | 31 | 17758 | 1761 |
PRSS8,SGCE,CD55,CAPN6,BVES,SLC39A8,CTDSPL,PRICKLE1,NENF,LOXL2,PJA2,SEPP1,TSPAN7,PARM1,ARHGEF16,CYP26A1,PITX2,PDLIM3,RNF128,PLOD2,H1F0,P4HA2,IMPAD1,OPN3,TINAGL1,LGMN,UNC5B,EGLN3,SLC27A3,MYLIP,OCLN |
| 2.316e-03 | -6.07 | GTPase activator activity | molecular function | GO:0005096 | 257 | 41 | 16491 | 1673 |
ARHGAP11A,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,RALBP1,IQGAP1,ARFGEF1,RGS20,SIPA1L2,ACAP2,LLGL2,RINL,SH3BP1,RGS3,TBCD,FAM13B,RANBP1,DAB2IP,RP2,IQGAP3,ALS2CL,DOCK4,ARAP2,TBC1D8B,RAPGEF2,ARHGDIB,GRTP1,RASA1,ABR,ARHGAP35,ARHGAP24,PLEKHG6,ARHGEF19,SIPA1L1,ARRB1,AGFG2,RGS14,TBC1D4,RAP1GAP |
| 2.331e-03 | -6.06 | FURUKAWA_DUSP6_TARGETS_PCI35_UP | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_UP | 68 | 15 | 17758 | 1761 |
MDK,CNTNAP1,C19orf66,ARHGEF37,ALPP,HLA-F,FXYD3,SECTM1,ENPP5,HERC5,MAPK11,DUSP4,EPB41L4A,HERC6,PARP9 |
| 2.331e-03 | -6.06 | VERNELL_RETINOBLASTOMA_PATHWAY_UP | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_UP | 68 | 15 | 17758 | 1761 |
FAM111A,BTG3,SPIN4,KCNK1,DCK,SNTB2,ZNF367,CDCA5,CDCA7L,EPS8,PBX3,DONSON,CNOT6L,BARD1,MELK |
| 2.334e-03 | -6.06 | GTPASE_REGULATOR_ACTIVITY | MSigDB lists | GTPASE_REGULATOR_ACTIVITY | 124 | 23 | 17758 | 1761 |
DOCK4,ARHGEF3,ARAP3,ARHGEF11,IQGAP1,RAPGEF2,RALBP1,RASA2,RGS20,ARFGEF1,ARHGDIB,RASA1,ABR,ARHGEF10L,RGS3,RANBP1,MADD,FGD6,RGS14,RAP1GAP,TIAM1,FGD1,FARP2 |
| 2.334e-03 | -6.06 | thalamus | COSMIC cancer mutations | thalamus | 296 | 45 | 17775 | 1757 |
CCNE2,PARP12,CDK17,RET,ETV5,XYLT1,ARFGEF1,TP53,TDRKH,PHLDA1,FAM101B,PPP2R3A,MDM1,CTSC,PTEN,DLG1,PIK3CA,GLB1L2,ECE1,TIAM1,ABCC1,MYO5B,AKT1,TBC1D8B,DEPDC4,PIK3R1,PDE5A,PYGO1,IDH1,GNA11,AHRR,GNAS,HS6ST1,NCOA3,PLEKHG6,JAK1,FGFR2,CSTF2,FZD5,SHROOM2,HOOK1,ABCA1,COBL,MELK,PCSK5 |
| 2.338e-03 | -6.06 | TSC2 (tuberous sclerosis 2) | protein interactions | 7249 | 63 | 15 | 16036 | 1726 |
MAPKAPK2,PLK1,SIRT1,CCND1,AKT1,RPS6KA1,CALM1,SPINT2,DAPK1,CDKN1B,RP2,ALDH3A2,RHEB,RRAGD,MDFI |
| 2.347e-03 | -6.05 | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 231 | 37 | 17758 | 1761 |
CALB2,COL4A5,IL27RA,SYTL4,CCNB1,TMPRSS4,ZNF385B,IL17RB,TOP2A,ADD3,IGF1R,NPNT,ZNRF2,FRAS1,SGK3,ADCK2,ATRNL1,PIKFYVE,MYBL1,TIAM1,TIPARP,SUSD3,LAMP2,CELSR2,PRSS23,AMFR,PIK3R1,SYBU,PARP4,TFAP2C,BLVRA,PLIN5,TMEM164,MAP2,LRIG1,GLA,ISOC1 |
| 2.351e-03 | -6.05 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 93 | 19 | 16441 | 1675 |
GCLM,LGALS3,AKT1,ITGA6,GCLC,STRADB,TGFBR1,BCL2L1,PELI3,GSTP1,LMNA,SCG2,DAPK1,NRG1,ITGAV,CTTN,FAIM,UNC5B,IFI6 |
| 2.354e-03 | -6.05 | BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) | protein interactions | 699 | 34 | 10 | 16036 | 1726 |
PLK1,ZWINT,SPC25,CDC20,NDC80,HDAC1,NUF2,BUB1,CENPE,CDK1 |
| 2.354e-03 | -6.05 | RXRB (retinoid X receptor beta) | protein interactions | 6257 | 34 | 10 | 16036 | 1726 |
THRB,NCOA3,NR3C1,THRA,ZDHHC12,FLYWCH2,PPARA,NR4A2,RARG,NR2C2 |
| 2.357e-03 | -6.05 | positive regulation of immune system process | biological process | GO:0002684 | 866 | 114 | 16441 | 1675 |
LAMP1,IL15,INPP5D,RPS6KA1,PSME2,IL27RA,PSME1,IL18,ITPR2,CD274,CAMK1D,PRKACA,CACNB4,TNFSF9,CALM2,DAPK2,PSMD1,RPS6KA2,ELMO2,IL6ST,PLCG2,BCL6,PIK3CA,PDE4D,PIK3CD,TMEM64,SCARA3,SLC39A10,LGMN,SMAGP,RASGRP1,SIRT1,CD55,RIPK2,TNIP1,AKT1,ITCH,CR2,PRKCQ,CD40,DUSP4,ITPR3,IRS2,PLCG1,PTPRJ,GPRC5B,LIMK1,AXL,NOD2,IRF7,F2RL1,DDX58,LGALS3,THEMIS2,HLA-E,CALM3,BTN3A1,PSMD10,SELL,NCKAP1,TEC,ETS1,EFNB1,HLA-A,CTNNBIP1,CA2,PTEN,GATA2,PIK3AP1,KCNN4,BAX,IGFBP2,MAPK11,WNT3A,CNPY3,SYK,SOCS5,HES1,KLK5,RHOA,PLSCR1,PSMB4,MICB,CALM1,PIK3R1,ANO6,RGCC,YES1,ELK1,FOS,BCAR1,PSMA4,GPLD1,CD83,GNAS,MAPKAPK2,CTSL,HLA-B,SWAP70,PVRL2,PELI2,CSF1,ITPR1,NFKBIA,NR4A3,NLRC5,PPP2R3C,KLK7,ARPC2,ICOSLG,FZD5,JAK3,IFIH1,TMEM173 |
| 2.361e-03 | -6.05 | POST_TRANSLATIONAL_PROTEIN_MODIFICATION | MSigDB lists | POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 470 | 66 | 17758 | 1761 |
NF2,SSH1,HDAC11,RET,ERBB2,TESK2,HDAC6,CCND1,DAPK2,IL31RA,PLK4,DUSP10,F2R,PTPRE,METAP2,MAP3K3,SIRT1,AKT1,PTPN9,DUSP4,ICMT,MAP3K6,STK17B,PTPRJ,LIMK1,STK38,MAPK12,PCSK5,PRKAA2,PINK1,CDK17,TGFBR1,TRIB2,SBF1,PKN1,MERTK,PPP2R3A,IGF1R,CDK16,PTEN,MAP3K9,DAPK1,TPST1,PRKG1,SGK3,SGK1,WWP1,PIM1,ERBB3,MYLIP,GAD1,CCDC88A,DDB2,AMFR,FURIN,STRADB,EIF2AK1,STK17A,PRDX4,MAPKAPK2,ACVRL1,NR4A3,AURKA,JAK3,UBE2C,HIPK3 |
| 2.364e-03 | -6.05 | autonomic_ganglia-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-neuroblastoma | 4133 | 457 | 17775 | 1757 |
ACACB,GAA,PPP4R4,ADD1,SSH1,HSPG2,AASS,AK7,VANGL1,ATP8A1,DNAJC3,RET,PPFIBP2,DHX8,FAM102B,VASH1,DPP8,GRM5,CALM2,CDKN2C,CYP1A1,PSMD1,ANKS6,MUC4,CTGF,PRICKLE3,OSBPL3,IL31RA,AOX1,KCNS3,PIK3CA,RCAN3,TIAM1,LAMP2,NWD1,ORAI2,KIFC2,ACVR1C,SH3BGRL,SERTAD4,KIF13A,CCNF,SPNS3,POR,COL12A1,ARHGEF26,AHRR,ENPP1,PLCG1,RBM47,DNM1L,FAM114A1,BMP1,DHTKD1,NFKBIZ,SERPINI1,UNC5B,DDX58,SEMA6B,SCN5A,FAM169A,TBC1D1,ITGA6,MERTK,MESDC2,MECOM,RABGGTA,DOPEY2,FRY,ITGA3,PIK3AP1,RIMS3,MEGF8,SLC16A6,AIM1,PRKG1,SORL1,CADPS2,C8orf58,PIKFYVE,ZMYM1,NCAM1,DGKG,NUP85,RIMS2,DDB2,B3GNT7,FADS2,KCNJ12,KLK5,HPS3,SLC37A1,PRSS23,KIF20A,TBC1D8B,SALL4,MICB,STAT4,AMER1,PIP4K2C,NPC2,ATP8B3,PLIN5,STX3,RASA1,FRMD4B,STK17A,DGKH,CACHD1,NCOA3,SLCO4A1,AP1AR,PLEKHH2,TJP3,SLC4A4,ISM1,DCK,ITPR1,SLC4A3,FAM83D,AGBL5,FGD6,CABIN1,NR4A2,DRP2,ARPC2,PER3,IFIH1,XDH,DOCK9,PLA2G4A,CCDC109B,SLC2A4,GRHL2,NQO1,CEP70,TRIP10,ST14,ACTR8,IQGAP1,RALBP1,ATP2C2,PKP2,IL13RA1,SNN,AIFM2,ZFYVE9,MUC16,ZNF75D,ST5,SP100,TRANK1,SH3BP1,DACT1,CNNM4,PHKA2,RAB27B,LRP11,CDKN2D,NR2C1,MYO5B,DOCK4,ENPP4,SSH3,COG2,FOXJ2,SYNE2,UTRN,TMEM144,CDCA2,SLC11A2,PRKCQ,PYGO1,C15orf39,ITPR3,FZD7,AMZ2,DDOST,CCDC149,AXL,PNPLA6,NR3C2,COBL,ISOC1,TNRC6C,CENPI,CTSZ,NUCB2,DNAH3,SLC25A43,HLA-A,NEO1,E2F7,FAM111A,ADD3,RNF128,ARSG,PTEN,CALD1,ALG13,ATP8B1,WWP1,MAPK11,ERBB3,TRIM62,TPCN1,NCOA2,OSGIN1,ACBD5,AMOTL2,ADAMTS2,RASGRF1,PDGFC,ZWINT,ARAP2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PARP4,DIAPH2,FBXO9,SNTB1,CNTNAP1,PITX2,ACADSB,PLOD2,FGFR2,ACVRL1,TBX18,AMMECR1,ABCB1,PGM2L1,GRIN2D,ETAA1,WDR62,FZD5,CPEB2,ESPL1,DEF6,OCLN,MELK,TLL2,TMEM131,JARID2,EXPH5,UNKL,LTBP1,UGT8,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,TMC1,FANCI,ABCD4,CHPF,SUSD2,ARHGEF10L,SIPA1L2,HSF2,SHC3,NPNT,MKRN3,MITF,ABCA2,POF1B,MYH14,SLC39A10,TLN2,MYRIP,MYBL1,NEB,RASGRP1,ZNF462,PLK1,ING1,CELSR2,RGAG1,EZR,CR2,ARHGDIB,IDH1,DZIP1L,DPYSL3,CXXC4,MAN2A2,PLEKHG6,PLCH1,MFAP3L,NEIL1,HPSE,MAP2,MADD,PIK3C2B,CAPN1,PCSK5,PRKAA2,SERPINE2,PEX6,PYROXD2,ADCK5,CNTNAP2,DHRS3,FBLN1,TNS3,FRAS1,KCNN4,COL6A1,HLA-C,ZRANB1,NCEH1,WNT3A,LRIF1,PLCB2,ALS2CL,CCDC88A,KDELR1,DPYSL5,PODXL2,PLEKHA6,TESK1,OXR1,SPATA13,VWA1,BTN3A2,STRADB,SCRIB,HEATR5A,C3orf58,MUM1L1,PRX,SOX13,GNAS,MAPKAPK2,ONECUT1,COL13A1,TMEM30A,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,AFAP1,RNF146,PROM2,USP43,KLF7,LMO7,NCKAP5,NF2,TP53,PDIA5,ERBB2,TDRKH,STIL,PDGFA,SS18,SLC25A48,ZNF687,WDR44,FRYL,PLCG2,PLK4,NOTCH3,OAS3,F2R,DVL2,FRS3,CTH,SUSD3,GCA,CLCN3,AKT1,PTGER4,FANCE,DOCK5,DAG1,DUOX1,TAPBP,IDE,BFSP1,C19orf66,ADAMTS14,TLE1,ABCA1,NDST3,PPP2R2D,ZMAT1,GLIS3,CMAS,PACSIN2,GOLIM4,CPEB4,ARHGEF11,LRP4,HAL,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,SLC9A2,NRP2,FZD6,DNAJB9,SIRPA,TMEM63A,FOXP2,IRF2BPL,LLGL2,A4GALT,BMP7,FAM63A,KIAA0319,ARVCF,SGK1,TSPAN13,ABCD1,ALDH7A1,MYO5A,TLE6,RBMS2,ATP2B1,PLAUR,ASPM,LITAF,MBNL3,TTC7A,MAML2,COL7A1,LEPR,CD83,FAT4,SCG2,PRCP,TMC5,CDCA7L,DTX4,FAM117A,GRAMD1C,HOXB13,ICOSLG,UBE2C,NDFIP1,HIPK3,ARHGEF9,L1CAM,AHR,ARHGEF4,GOLGB1,DIS3L,CD33 |
| 2.366e-03 | -6.05 | Sema4D induced cell migration and growth-cone collapse | REACTOME pathways | R-HSA-416572 | 24 | 8 | 8202 | 867 |
MYL9,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B |
| 2.370e-03 | -6.04 | extracellular matrix disassembly | biological process | GO:0022617 | 121 | 23 | 16441 | 1675 |
COL9A3,CASP3,TIMP2,COL6A2,HSPG2,FURIN,COL18A1,COL4A5,COL7A1,COL12A1,CTSL,MMP15,CDH1,COL13A1,CTSV,COL6A1,EXOC8,BMP1,ADAM15,KLK7,COL16A1,CAPN1,TLL2 |
| 2.370e-03 | -6.04 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 121 | 23 | 16441 | 1675 |
PLK1,PRKAA2,PINK1,AKT1,TGFBR1,PDK3,CCNB1,PRKACA,PDGFB,CDK1,CDK5R1,MAPKAPK2,RPS6KA2,ADRBK1,CSNK1G1,SGK3,SGK1,AURKA,STK39,MAST4,SYK,HIPK3,MAPK12 |
| 2.370e-03 | -6.04 | lysosomal membrane | cellular component | GO:0005765 | 269 | 42 | 17570 | 1756 |
LAMP1,GAA,SORT1,CD63,TMEM55B,TMEM63A,ABCD4,M6PR,MARCH8,PQLC2,AP1M2,ZNRF2,VASN,COL6A1,DRAM1,ABCA2,SLC44A2,PLEKHF1,ECE1,MARCH2,TSPAN1,TMEM9,TPCN1,LAMP3,LAMP2,EVA1A,MMD,IFITM3,OSTM1,LITAF,SLC11A2,GNA11,RHEB,ATP13A2,GPLD1,SCARB2,ENPP1,HPSE,ARRB1,CTSA,PLD1,STARD3NL |
| 2.370e-03 | -6.04 | lytic vacuole membrane | cellular component | GO:0098852 | 269 | 42 | 17570 | 1756 |
LAMP1,GAA,SORT1,CD63,TMEM55B,TMEM63A,ABCD4,M6PR,MARCH8,PQLC2,AP1M2,ZNRF2,VASN,COL6A1,DRAM1,ABCA2,SLC44A2,PLEKHF1,ECE1,MARCH2,TSPAN1,TMEM9,TPCN1,LAMP3,LAMP2,EVA1A,MMD,IFITM3,OSTM1,LITAF,SLC11A2,GNA11,RHEB,ATP13A2,GPLD1,SCARB2,ENPP1,HPSE,ARRB1,CTSA,PLD1,STARD3NL |
| 2.371e-03 | -6.04 | GSE17721_LPS_VS_PAM3CSK4_16H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_16H_BMDM_UP | 192 | 32 | 17758 | 1761 |
CASP3,SPRED1,IL15RA,LGALS3,PTTG1,IL18,F11R,CD274,TMCC3,CST3,SORL1,CD70,PIM1,HLA-C,SGCB,SNX10,TIAM1,LAMP2,ELK3,RIPK2,FNDC3A,GNA11,POR,ARF4,SCARB2,ITPR1,HMGA1,ETAA1,PLOD3,ARPC2,RGS14,GEM |
| 2.371e-03 | -6.04 | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_DN | 192 | 32 | 17758 | 1761 |
IL15RA,TCTN2,ABCG2,KCTD12,CCDC92,RCN1,FOXP2,APOBEC3B,PIK3AP1,KLF3,SGK3,SORL1,SGK1,FAM102A,IRF2,TESK1,BCL9,NUB1,PARP4,SAV1,RNPEP,RNF19B,ZFAND5,PRDX4,NUCB1,TWSG1,RAP2C,TRIOBP,HDAC1,NFKBIZ,RELL1,STARD3NL |
| 2.371e-03 | -6.04 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | 192 | 32 | 17758 | 1761 |
LASP1,ARHGEF3,ADD1,ENO2,ARHGEF11,RASA2,TAP1,NUCB2,HERC6,SLC20A1,ANO1,FOXP2,DOPEY2,SESN3,SH3BP1,DOK4,IQCE,XYLT2,PIK3CD,FAH,PAQR7,UTRN,ARHGDIB,ASB13,PLCG1,LRIG1,MADD,NR4A3,CABIN1,NFKBIZ,ST3GAL1,ESYT2 |
| 2.371e-03 | -6.04 | GSE17721_CTRL_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_12H_BMDM_DN | 192 | 32 | 17758 | 1761 |
LZTFL1,NDRG2,IL18,SLC1A3,INTS8,DNER,HOXB2,TNFSF9,REPS1,APPBP2,LMO4,SNX16,CD70,IGFBP2,CTTN,PIM1,MX1,GFPT1,CPD,PMPCB,SYPL1,FBLN5,RIPK2,TESK1,NUB1,CYS1,PSMA4,GDE1,PVRL2,HOXA9,HDAC1,E2F8 |
| 2.371e-03 | -6.04 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | 192 | 32 | 17758 | 1761 |
MAN2B2,SIGIRR,ENO2,MRPS15,BLVRB,IL27RA,NUCB2,PKN1,LTBP3,M6PR,PSMD1,TBCD,FAM102A,CITED2,TIAM1,IFITM3,SEPT6,S100A4,PIK3R1,MAP3K6,ATP13A2,SOCS3,OPTN,ATP1A1,SEMA4D,NGFRAP1,AGBL5,INPP4B,CABIN1,NDFIP1,TOB1,NRBP1 |
| 2.371e-03 | -6.04 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | 192 | 32 | 17758 | 1761 |
CASP3,RUNX2,LGALS3,SLC25A13,BARD1,CARD10,B4GALNT1,BTG3,UBE2T,RRBP1,CD70,SULT2B1,C12orf75,F2R,MED30,OSGIN1,SUSD3,CPD,SEC61B,LITAF,VEZT,LRRC1,RNPEP,GABARAPL1,FRMD4B,AHRR,NUCB1,ENPP1,RYK,HOOK1,AHR,EHD1 |
| 2.374e-03 | -6.04 | Endochondral Ossification | WikiPathways | WP474 | 65 | 16 | 4455 | 516 |
RUNX2,AKT1,CDKN1C,THRA,CALM1,SOX9,CALM3,RUNX3,PRKACA,CALM2,ENPP1,TIMP3,IGF1R,BMP7,CTSV,CAB39 |
| 2.376e-03 | -6.04 | cell division | biological process | GO:0051301 | 458 | 66 | 16441 | 1675 |
CCNE2,SPC25,ACTR8,PTTG1,NDC80,NUF2,BCL2L1,CCNB1,CCND1,WEE1,SETDB2,CNTRL,KIF14,DIXDC1,CKS2,PLK1,SEPT6,CDC20,KIF13A,CDCA2,NUSAP1,CCNF,ANLN,CDK1,FZD7,TRIOBP,ARF6,RGS14,REEP4,PPP2R2D,CKAP2,KLHL13,ARHGEF11,CIT,ETV5,CDCA8,KIF23,TEAD3,SAC3D1,TOP2A,LLGL2,SNX18,NEK2,BUB1,WNT3A,ZWINT,RHOA,KIF20A,TACC1,ASPM,DIAPH2,BORA,BCAR1,KIF11,RASA1,FAM64A,FGFR2,CDCA5,FAM83D,AURKA,CENPE,NDE1,NCAPG2,CCNB2,UBE2C,ESPL1 |
| 2.379e-03 | -6.04 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | 169 | 29 | 17758 | 1761 |
SUSD3,BIN1,SIGIRR,ZNF395,HAPLN3,GALNT12,MORC4,STMN3,IGSF8,EPHA1,NUCB2,BBS2,LTBP3,ZNF275,TMEM63A,SCML1,COQ10A,LYPD3,NGFRAP1,IL6ST,TSPAN18,TMEM143,PIK3CD,SOX8,CNOT6L,RCAN3,ZRANB1,PPP2R2D,SNPH |
| 2.394e-03 | -6.03 | large_intestine-colon | COSMIC cancer mutations | large_intestine-colon | 1346 | 164 | 17775 | 1757 |
HSPG2,AK7,HEBP1,TSC22D3,FHDC1,TAP1,PPFIBP2,FAM102B,NENF,HDAC6,FAM101B,SPTB,CNTRL,RGS3,SLC44A1,PHTF1,ANKFN1,PIK3CA,ATRNL1,MYH14,TINAGL1,TMEM37,TLN2,TIAM1,MYRIP,MYBL1,NEB,RASGRP1,XKR8,SGCE,CELSR2,NFE2L1,KIF13A,LOXL2,LHFPL2,CYP4F3,TYSND1,COL12A1,AHRR,MAN2A2,PLEKHG6,TMEM164,KCNK1,PLK2,GNPTAB,DHTKD1,ARRDC1,PIK3C2B,SEMA6B,NFKBIE,ETV5,CNTNAP2,SAMD9,TSPAN7,KIAA1161,RAVER2,FRY,ITGA3,FRAS1,AIM1,OPN3,SORL1,CD70,PIKFYVE,PLCB2,PPP6R1,RIMS2,ELK3,PCDH1,AMER1,EIF2AK1,RNF113A,ANTXR1,SEMA4D,UTP14C,ITPR1,FGD6,PCDH19,MDH1,XDH,ADAMTS16,DOCK9,TP53,TESK2,IL27RA,TDRKH,PRSS22,SLC7A2,BCL2L1,DDR1,SYTL2,MUC16,ACAP2,ST5,TRANK1,EFR3A,KIF14,PLCG2,LHX6,PLK4,DAB2IP,RTKN2,SCN2A,NR2C1,SCN3A,MX1,CLCN3,ERLEC1,CYB5R2,CDC20,ITPR3,FZD7,NFIX,DUOX1,DNAJC10,SHROOM3,AXL,TRIOBP,SLC25A30,ABCA1,COBL,TNRC6C,HAPLN3,MACC1,GABRG2,PKN1,DNAH3,HMGXB4,SNTA1,ITGB8,PHF7,PTEN,CTSC,CALD1,DRAM1,BUB1,CNOT6L,NCOA2,DLGAP1,AMOTL2,ADAMTS2,RASGRF1,ARAP2,RHOA,BCL9,ASPM,ZKSCAN2,PARP4,TTC7A,SNTB1,GPLD1,PITX2,ARHGAP24,FAT4,TBX18,NETO2,PPM1H,ARRB1,CENPE,ZMIZ1,NCAPG2,CPEB2,DIS3L,TMEM131 |
| 2.395e-03 | -6.03 | UDP-glycosyltransferase activity | molecular function | GO:0008194 | 136 | 25 | 16491 | 1673 |
CHSY3,B3GALT6,UGT8,B3GNT2,GALNT12,XYLT1,MGAT4B,HEXB,GYLTL1B,C1GALT1C1,MGAT5B,GALNT7,POMGNT1,B4GALT4,CHPF,B4GALNT1,GALNT3,B3GALNT1,MGAT4A,ALG13,XYLT2,A4GALT,PLOD3,MGAT5,GCNT1 |
| 2.404e-03 | -6.03 | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | 117 | 22 | 17758 | 1761 |
PVRL4,CPEB4,IL13RA1,SYTL4,HEATR5A,CCNF,TMPRSS4,GLT8D2,SRPX2,ZNF469,ARF4,FANCI,SYTL2,AP1M2,RAB11FIP1,SLC44A2,VAT1,TACSTD2,MARCH2,NAGA,GPR161,S100A6 |
| 2.405e-03 | -6.03 | TGCTTTG,MIR-330 | MSigDB lists | TGCTTTG,MIR-330 | 320 | 48 | 17758 | 1761 |
MTM1,RUNX2,SCOC,NF2,ZCCHC24,DCAF7,MIER3,NKRF,RAB6A,TRIB2,BMP2K,GRM5,UBE2Q2,ADD3,ANKS1B,ZNRF2,LHX6,PRKG1,IFIT1,NCEH1,NPTXR,ARMCX6,TIPARP,NCOA2,ATP2B1,IGSF3,METAP2,TRAK2,BCL9,ITCH,FOXJ2,SYBU,MYEOV,RUNX3,GALNT7,PTGFRN,DAG1,SP4,DCP2,SOX13,DPYSL3,RND3,SYT7,PHLPP2,RAP2C,NR4A3,YOD1,ARHGEF9 |
| 2.408e-03 | -6.03 | neuroblastoma | COSMIC cancer mutations | neuroblastoma | 4134 | 457 | 17775 | 1757 |
ACACB,GAA,PPP4R4,ADD1,SSH1,HSPG2,AASS,AK7,VANGL1,ATP8A1,DNAJC3,RET,PPFIBP2,DHX8,FAM102B,VASH1,DPP8,GRM5,CALM2,CDKN2C,CYP1A1,PSMD1,ANKS6,MUC4,CTGF,PRICKLE3,OSBPL3,IL31RA,AOX1,KCNS3,PIK3CA,RCAN3,TIAM1,LAMP2,NWD1,ORAI2,KIFC2,ACVR1C,SH3BGRL,SERTAD4,KIF13A,CCNF,SPNS3,POR,COL12A1,ARHGEF26,AHRR,ENPP1,PLCG1,RBM47,DNM1L,FAM114A1,BMP1,DHTKD1,NFKBIZ,SERPINI1,UNC5B,DDX58,SEMA6B,SCN5A,FAM169A,TBC1D1,ITGA6,MERTK,MESDC2,MECOM,RABGGTA,DOPEY2,FRY,ITGA3,PIK3AP1,RIMS3,MEGF8,SLC16A6,AIM1,PRKG1,SORL1,CADPS2,C8orf58,PIKFYVE,ZMYM1,NCAM1,DGKG,NUP85,RIMS2,DDB2,B3GNT7,FADS2,KCNJ12,KLK5,HPS3,SLC37A1,PRSS23,KIF20A,TBC1D8B,SALL4,MICB,STAT4,AMER1,PIP4K2C,NPC2,ATP8B3,PLIN5,STX3,RASA1,FRMD4B,STK17A,DGKH,CACHD1,NCOA3,SLCO4A1,AP1AR,PLEKHH2,TJP3,SLC4A4,ISM1,DCK,ITPR1,SLC4A3,FAM83D,AGBL5,FGD6,CABIN1,NR4A2,DRP2,ARPC2,PER3,IFIH1,XDH,DOCK9,PLA2G4A,CCDC109B,SLC2A4,GRHL2,NQO1,CEP70,TRIP10,ST14,ACTR8,IQGAP1,RALBP1,ATP2C2,PKP2,IL13RA1,SNN,AIFM2,ZFYVE9,MUC16,ZNF75D,ST5,SP100,TRANK1,SH3BP1,DACT1,CNNM4,PHKA2,RAB27B,LRP11,CDKN2D,NR2C1,MYO5B,DOCK4,ENPP4,SSH3,COG2,FOXJ2,SYNE2,UTRN,TMEM144,CDCA2,SLC11A2,PRKCQ,PYGO1,C15orf39,ITPR3,FZD7,AMZ2,DDOST,CCDC149,AXL,PNPLA6,NR3C2,COBL,ISOC1,TNRC6C,CENPI,CTSZ,NUCB2,DNAH3,SLC25A43,HLA-A,NEO1,E2F7,FAM111A,ADD3,RNF128,ARSG,PTEN,CALD1,ALG13,ATP8B1,WWP1,MAPK11,ERBB3,TRIM62,TPCN1,NCOA2,OSGIN1,ACBD5,AMOTL2,ADAMTS2,RASGRF1,PDGFC,ZWINT,ARAP2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PARP4,DIAPH2,FBXO9,SNTB1,CNTNAP1,PITX2,ACADSB,PLOD2,FGFR2,ACVRL1,TBX18,AMMECR1,ABCB1,PGM2L1,GRIN2D,ETAA1,WDR62,FZD5,CPEB2,ESPL1,DEF6,OCLN,MELK,TLL2,TMEM131,JARID2,EXPH5,UNKL,LTBP1,UGT8,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,TMC1,FANCI,ABCD4,CHPF,SUSD2,ARHGEF10L,SIPA1L2,HSF2,SHC3,NPNT,MKRN3,MITF,ABCA2,POF1B,MYH14,SLC39A10,TLN2,MYRIP,MYBL1,NEB,RASGRP1,ZNF462,PLK1,ING1,CELSR2,RGAG1,EZR,CR2,ARHGDIB,IDH1,DZIP1L,DPYSL3,CXXC4,MAN2A2,PLEKHG6,PLCH1,MFAP3L,NEIL1,HPSE,MAP2,MADD,PIK3C2B,CAPN1,PCSK5,PRKAA2,SERPINE2,PEX6,PYROXD2,ADCK5,CNTNAP2,DHRS3,FBLN1,TNS3,FRAS1,KCNN4,COL6A1,HLA-C,ZRANB1,NCEH1,WNT3A,LRIF1,PLCB2,ALS2CL,CCDC88A,KDELR1,DPYSL5,PODXL2,PLEKHA6,TESK1,OXR1,SPATA13,VWA1,BTN3A2,STRADB,SCRIB,HEATR5A,C3orf58,MUM1L1,PRX,SOX13,GNAS,MAPKAPK2,ONECUT1,COL13A1,TMEM30A,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,AFAP1,RNF146,PROM2,USP43,KLF7,LMO7,NCKAP5,NF2,TP53,PDIA5,ERBB2,TDRKH,STIL,PDGFA,SS18,SLC25A48,ZNF687,WDR44,FRYL,PLCG2,PLK4,NOTCH3,OAS3,F2R,DVL2,FRS3,CTH,SUSD3,GCA,CLCN3,AKT1,PTGER4,FANCE,DOCK5,DAG1,DUOX1,TAPBP,IDE,BFSP1,C19orf66,ADAMTS14,TLE1,ABCA1,NDST3,PPP2R2D,ZMAT1,GLIS3,CMAS,PACSIN2,GOLIM4,CPEB4,ARHGEF11,LRP4,HAL,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,SLC9A2,NRP2,FZD6,DNAJB9,SIRPA,TMEM63A,FOXP2,IRF2BPL,LLGL2,A4GALT,BMP7,FAM63A,KIAA0319,ARVCF,SGK1,TSPAN13,ABCD1,ALDH7A1,MYO5A,TLE6,RBMS2,ATP2B1,PLAUR,ASPM,LITAF,MBNL3,TTC7A,MAML2,COL7A1,LEPR,CD83,FAT4,SCG2,PRCP,TMC5,CDCA7L,DTX4,FAM117A,GRAMD1C,HOXB13,ICOSLG,UBE2C,NDFIP1,HIPK3,ARHGEF9,L1CAM,AHR,ARHGEF4,GOLGB1,DIS3L,CD33 |
| 2.410e-03 | -6.03 | platelet-derived growth factor receptor binding | molecular function | GO:0005161 | 15 | 6 | 16491 | 1673 |
PDGFA,PDGFC,TYMP,PTPRJ,PDGFB,PTEN |
| 2.412e-03 | -6.03 | DURAND_STROMA_NS_UP | MSigDB lists | DURAND_STROMA_NS_UP | 154 | 27 | 17758 | 1761 |
MYL9,LMO7,FBLIM1,EZR,TCF7,GDF15,TMEM170B,MAP3K6,TNFSF9,PRRG4,PARM1,FZD7,PRKAG2,RBM47,RNF128,LLGL2,CTSC,MFSD2A,ITPR1,RUNDC3B,FAM110C,ATRNL1,ALDH7A1,UNC5B,OSR1,RAB27B,F2R |
| 2.415e-03 | -6.03 | CFTR (cystic fibrosis transmembrane conductance regulator) | protein interactions | 1080 | 192 | 34 | 16036 | 1726 |
GRN,LMO7,LGALS3,LRRFIP2,PSME2,EPS8,HDAC6,PRKACA,REPS1,BCAP31,RCN1,EPCAM,KIF5B,CDH1,RANBP1,PRKG1,SORL1,MARCH2,TIAM1,CLCN3,PLEKHA6,PSMB4,SEPT6,AMFR,EMC2,EZR,ERBB2IP,GNA11,TJP3,SLC9A6,RYK,SARAF,SH3BGRL2,HSPB1 |
| 2.427e-03 | -6.02 | REACTOME_DAG_AND_IP3_SIGNALING | MSigDB lists | REACTOME_DAG_AND_IP3_SIGNALING | 31 | 9 | 17758 | 1761 |
CALM2,PLCG1,ADRBK1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 2.453e-03 | -6.01 | negative regulation of catalytic activity | biological process | GO:0043086 | 815 | 108 | 16441 | 1675 |
CASP3,SPRED1,PPP4R4,NF2,NQO1,RPS6KA1,CAST,DNAJC3,PSME2,IQGAP1,PTTG1,ARFGEF1,TP53,F11R,PSME1,HDAC6,SYTL2,CDKN2C,APLP2,PSMD1,CABP1,RGS3,DUSP10,CDKN1B,DAB2IP,CRY2,IFIT1,DLG3,CDKN2D,CHP1,PLK1,SIRT1,PPIF,CAMSAP3,TIMP2,AKT1,CDC20,PRKAR2B,PIF1,PKMYT1,PPP1R14C,DUSP4,POR,SOCS3,IRS2,NEIL1,PTPRJ,PPP2R5A,CORO1C,LIMK1,STK38,SERPINB6,SERPINI1,GLA,RGS14,HSPB1,ARFGEF3,ANXA3,SORT1,LMTK3,PPP1R2,CDKN1C,SERPINE2,UBASH3B,PSMD10,PKN1,TRIB2,GSTP1,AIP,TIPRL,SH2D4A,CD109,TFAP4,IGF1R,PTEN,BMP7,CST3,TMBIM6,SORL1,BUB1,SPRY2,SOCS5,PSMB4,PLAUR,FURIN,COL7A1,EPHA1,PSMA4,LEPR,MAPK8IP1,PLIN5,FAS,CDK5RAP1,TIMP3,PRKAG2,SERPINA1,SEMA4D,SPINT2,SH3BP4,ARRB1,CABIN1,SERPINB1,UBE2C,CPEB2,IFI6,HIPK3,PKIA,EGLN1 |
| 2.463e-03 | -6.01 | regulation of fatty acid beta-oxidation | biological process | GO:0031998 | 15 | 6 | 16441 | 1675 |
IRS2,TWIST1,AKT1,TYSND1,PLIN5,PPARA |
| 2.469e-03 | -6.00 | PRAMOONJAGO_SOX4_TARGETS_DN | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_DN | 49 | 12 | 17758 | 1761 |
LAMP1,BIN1,KIF20A,DLGAP5,CTSC,CALD1,ADAM15,CCNB1,TMEM14A,PTGES,MCCC2,ACOT7 |
| 2.469e-03 | -6.00 | MODULE_485 | MSigDB lists | MODULE_485 | 49 | 12 | 17758 | 1761 |
FADS2,DLGAP5,SSH1,NQO1,BDH1,MYBL2,AURKA,BUB1,HOOK1,GLT8D2,ARHGEF16,ELF3 |
| 2.482e-03 | -6.00 | response to organic cyclic compound | biological process | GO:0014070 | 798 | 106 | 16441 | 1675 |
CASP3,SSH1,NQO1,FOXM1,IL15,THRA,ERBB2,IL18,ITPR2,BCL2L1,CCNB1,PRKACA,PDGFB,SDC1,CALM2,CCND1,CYP1A1,CDH1,CTGF,DPYSL2,FOSB,SRR,ABCA2,CLDN4,CDKN1B,GOT1,PDE4D,IFIT1,CDKN2D,TIPARP,NR2C1,SP5,CYP1B1,THRB,RIPK2,AKT1,CITED4,PTPRU,CASP9,EZR,AGO4,PRKCQ,PRKAR2B,PRKRA,IDH1,SOCS3,MDK,DUOX1,ATP1A1,MAP2,NOD2,NR3C2,LIFR,NR2C2,DDX58,GRN,ANXA3,NKX3-1,DGKQ,CALM3,SELL,GABRG2,TGFBR1,ETS1,TFAP4,CA2,IGF1R,PTEN,BMP7,CST3,BAX,IGFBP2,KLF9,PIM1,CITED2,PAQR7,RHOA,SHMT1,NR3C1,RAPGEF2,NR4A1,CALM1,GRIN1,PPARA,ELK1,FOS,FAS,GPLD1,CD83,FECH,GNAS,MMP15,NCOA3,TIMP3,NR1D2,CTSV,NFKBIA,NR4A3,AURKA,NR4A2,GPER1,HOXB13,ARSB,PTGES,RARG,TMEM173 |
| 2.483e-03 | -6.00 | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | MSigDB lists | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | 296 | 45 | 17758 | 1761 |
CCNE2,PPP1R2,S100A11,CNOT8,C5orf30,PSMD10,MORF4L2,CCNB1,CRABP2,S100A2,FZD6,TOP2A,KIF5B,CDKN2C,SS18,WEE1,ACAP2,CALD1,AHCY,RP2,F2R,CKS2,LAMP2,ZWINT,LPGAT1,UBE2A,GLO1,LOXL2,BLVRA,GTF2A2,CCNF,KIF11,H2AFV,RASA1,STK17A,PRDX4,MAPKAPK2,DDOST,DCK,DBI,PRPS2,PGRMC1,HMGA1,ITGAV,UBE2C |
| 2.489e-03 | -6.00 | MARSON_BOUND_BY_FOXP3_STIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_STIMULATED | 962 | 122 | 17758 | 1761 |
ARHGAP11A,CCNI,SLC25A24,AVPI1,TXN,ADD1,TP53,TESK2,FTH1,CD274,CAMK1D,SLC20A1,TMPRSS4,SYTL2,IER3,APLP2,CYP1A1,LRRC6,CTGF,WDR44,DPYSL2,RGS3,CABP1,CDKN1B,TUBG1,IRF2,DIXDC1,ACSL4,ECE1,SLC39A10,TIPARP,SEPHS1,CPD,ORAI2,CENPA,COQ10B,SEPT6,LYRM1,PTGER4,MTRF1L,IGSF8,SLC11A2,GLO1,ARHGDIB,DNAJB14,GTF2A2,ZFAND5,IDH1,SESN1,ATP10D,RHEB,CMTM7,AMZ2,TMEM164,PTPRJ,PPP2R5A,MAP2,CDK19,ABHD12,RBL1,WFS1,SIPA1L1,CAB39,MRPS28,ANXA9,C1orf43,NRGN,CBX7,CDK17,FRMD6,DAP,CENPI,ERI2,PDIA3,NCKAP1,ETS1,TNFRSF19,PRRG4,AKIRIN1,KIF5B,MDM1,CTSC,ZNRF2,KCNN4,ATP5H,PPP4R1,FAM63A,SGK1,PIM1,CNOT6L,PIKFYVE,CITED2,LRIF1,S100A6,FAM69A,FAH,WBP5,GFPT1,SUN2,SYPL1,DDB2,TGIF1,RHOA,ZWINT,FBXO9,FAM133B,BCAR1,GLT8D2,GLCE,SCARB2,NCOA3,FAM64A,CSF1,TMEM30A,CGREF1,P4HA3,S100A5,MAP3K5,NDFIP1,NRBP1,SNX30,XDH |
| 2.491e-03 | -5.99 | ovary-low_malignant_potential_(borderline)_tumour-mucinous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-mucinous | 37 | 10 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 2.495e-03 | -5.99 | regulation of peptidyl-threonine phosphorylation | biological process | GO:0010799 | 36 | 10 | 16441 | 1675 |
PLK1,CALM2,SPRED1,PRKAG2,RIPK2,BMP7,CALM1,CAB39,CALM3,SPRY2 |
| 2.495e-03 | -5.99 | reactive nitrogen species metabolic process | biological process | GO:2001057 | 36 | 10 | 16441 | 1675 |
CALM2,NQO1,AKT1,CALM1,CALM3,SLC7A2,SPR,POR,ZDHHC21,CYP1B1 |
| 2.500e-03 | -5.99 | human chr9p22.3 | chromosome location | human chr9p22.3 | 9 | 4 | 26250 | 1887 |
SMARCA2,TTC39B,PSIP1,ZDHHC21 |
| 2.505e-03 | -5.99 | REACTOME_L1CAM_INTERACTIONS | MSigDB lists | REACTOME_L1CAM_INTERACTIONS | 82 | 17 | 17758 | 1761 |
SCN5A,RPS6KA1,EZR,ALCAM,RANBP9,SPTB,NRP2,CNTNAP1,RPS6KA2,DPYSL2,DLG1,SPTBN5,ITGAV,DLG3,NCAM1,SCN2A,L1CAM |
| 2.505e-03 | -5.99 | STEIN_ESR1_TARGETS | MSigDB lists | STEIN_ESR1_TARGETS | 82 | 17 | 17758 | 1761 |
CCNE2,PAPSS2,PRSS23,CELSR2,SLC39A8,MICB,TSC22D3,RET,SOX13,BTG3,SGK1,GLA,RAB27B,TIAM1,TIPARP,NCAPG2,ABCG1 |
| 2.514e-03 | -5.99 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 162 | 28 | 17758 | 1761 |
MTM1,PGM1,CTHRC1,ARAP2,SERPINE2,PQLC3,SALL4,CKAP2,DDIT4L,TAP1,TP53,FGF19,CCND1,CPNE2,PLK2,PTK7,CALD1,BAX,DAPK1,PIEZO1,EGLN3,WNT3A,ZNF365,C12orf75,CPPED1,DEF6,IGDCC4,EGLN1 |
| 2.516e-03 | -5.99 | E1-E2_ATPase | pfam domains | PF00122 | 36 | 10 | 16629 | 1696 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.520e-03 | -5.98 | response to endoplasmic reticulum stress | biological process | GO:0034976 | 226 | 37 | 16441 | 1675 |
ADD1,DNAJB2,DNAJC3,TMX4,TP53,FBXO2,PDIA5,PDIA3,DNAJB11,FBXO6,DNAJB9,LMNA,PDIA4,CCND1,BAX,UBE2J1,TMBIM6,DAB2IP,SELK,MYDGF,PDIA6,CTDSP2,CTH,GFPT1,SEC61B,ERLEC1,AMFR,PIK3R1,ERO1A,TXNDC11,CASP4,DNAJC10,WIPI1,WFS1,ITPR1,YOD1,MAP3K5 |
| 2.522e-03 | -5.98 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 185 | 31 | 17758 | 1761 |
LAMP2,TRIM2,ATP9A,SNTB2,ZCCHC24,LRP4,ASAH1,GGH,MORF4L2,LACTB2,LDB2,ATP10D,LGALS3BP,TEAD3,LMNA,SCML1,FUCA1,PDGFA,TIMP3,UEVLD,KCNK1,RRBP1,MTMR11,KLF9,EPHB4,CTTN,ARSB,NAGA,MYO5A,DENND5B,XKR8 |
| 2.522e-03 | -5.98 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 185 | 31 | 17758 | 1761 |
PLK1,PPIF,CD55,LGALS3,CKAP2,SLC25A13,SEPT6,MYBL2,EZR,CR2,NUSAP1,ASB13,RNF19B,TIPRL,HMGXB4,BCAR3,TTC21B,KIF5B,NR1D2,LMO4,ALG13,IL6ST,CABIN1,KLF9,GLA,LRRK1,MAP3K5,PLIN3,SPRY2,MAFF,JARID2 |
| 2.532e-03 | -5.98 | V$LMO2COM_02 | MSigDB lists | V$LMO2COM_02 | 232 | 37 | 17758 | 1761 |
GAS2L1,BIN1,CMAS,CPEB4,CAST,C6orf106,NDRG2,ISYNA1,CAMK1D,PKN1,FAM101B,SPTB,NRP2,PPP2R3A,ARHGEF10L,FOXP2,ANKS1B,LHX6,MITF,BCL6,TACC1,FZD4,NR3C1,NR4A1,AMFR,ZBTB7B,GPLD1,PITX2,PLEKHG6,ACVRL1,SYT7,PVRL2,ALPK3,LIFR,TOB1,PKIA,CAPN1 |
| 2.534e-03 | -5.98 | LEIN_PONS_MARKERS | MSigDB lists | LEIN_PONS_MARKERS | 89 | 18 | 17758 | 1761 |
ADAMTS2,TSC22D3,CALM1,EIF5A2,CALM3,TNS1,LTBP3,CD83,DPYSL3,KIF5B,ENDOD1,CALM2,STEAP2,NRG1,HMGA1,PANX2,MARCH2,CAPN1 |
| 2.552e-03 | -5.97 | BIOCARTA_PAR1_PATHWAY | MSigDB lists | BIOCARTA_PAR1_PATHWAY | 37 | 10 | 17758 | 1761 |
ARHGEF19,ARHGEF3,RHOA,ARHGEF11,PIK3R1,PIK3CA,F2R,ARHGEF9,ARHGEF16,ARHGEF4 |
| 2.552e-03 | -5.97 | AMIT_EGF_RESPONSE_60_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_60_MCF10A | 37 | 10 | 17758 | 1761 |
SLC35D2,HES1,CTGF,CYR61,RND3,PLK2,CALD1,PTGER4,KLF7,IER3 |
| 2.552e-03 | -5.97 | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | MSigDB lists | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | 43 | 11 | 17758 | 1761 |
CASP3,PRODH,SLC25A4,DNM1L,NR4A1,CPT2,SIVA1,TP53,BAX,BCL2L1,PLS3 |
| 2.555e-03 | -5.97 | KEGG_COLORECTAL_CANCER | MSigDB lists | KEGG_COLORECTAL_CANCER | 62 | 14 | 17758 | 1761 |
CCND1,CASP3,RHOA,AKT1,CASP9,PIK3R1,PIK3CA,TP53,BAX,TCF7,TGFBR1,PIK3CD,APC2,FOS |
| 2.561e-03 | -5.97 | lumenal side of membrane | cellular component | GO:0098576 | 31 | 9 | 17570 | 1756 |
HLA-B,TAPBP,NUCB1,HLA-E,HLA-F,CTSA,HLA-C,BCAP31,HLA-A |
| 2.567e-03 | -5.97 | B2M (beta-2-microglobulin) | protein interactions | 567 | 29 | 9 | 16036 | 1726 |
HLA-B,TAPBP,PRSS23,HLA-E,HLA-F,PTTG1,TAP1,HLA-C,HLA-A |
| 2.569e-03 | -5.96 | PTPN11 (protein tyrosine phosphatase, non-receptor type 11) | protein interactions | 5781 | 157 | 29 | 16036 | 1726 |
PPIF,LGALS3,INPP5D,RET,PIK3R1,EFHD2,ERBB2,CD274,DDR1,BCAR1,LEPR,SIRPA,SOCS3,IRS2,PLCG1,CYP1A1,IGF1R,JAK1,AXL,IL6ST,PLCG2,ERBB3,LRRK1,MAP3K5,LIFR,SPRY2,GAB1,CD33,FRS3 |
| 2.578e-03 | -5.96 | Golgi stack | cellular component | GO:0005795 | 124 | 23 | 17570 | 1756 |
CHSY3,B3GALT6,ATL1,SORT1,GOLIM4,COG2,FURIN,B4GALT4,BCAP31,NCS1,HLA-A,CHPF,GALNT3,NUCB1,FUT2,FUT8,FUT1,SORL1,RAB27B,ST3GAL1,GCNT1,GOLGB1,SULF2 |
| 2.579e-03 | -5.96 | GSE17721_CTRL_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDM_DN | 193 | 32 | 17758 | 1761 |
RUNX2,KLHL13,RASA2,RGS20,DNAJB11,BCL2L1,APPBP2,ST5,ADORA1,IGSF9,LYPD3,KCNN4,LMO4,LHX6,PLK4,CDH3,TAGLN2,NOTCH3,MYLIP,CYP1B1,RIPK2,PLSCR1,SALL4,ARFRP1,ABR,MAPKAPK2,RBM47,PPP2R5A,HOXA9,NFKBIA,HDAC1,PTGES |
| 2.579e-03 | -5.96 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 193 | 32 | 17758 | 1761 |
UGT8,NFKBIE,AASS,DAP,ETV5,TAP1,NDRG2,IL18,GDF15,VASH1,SEPP1,HOXB2,LGALS3BP,PDIA4,ATG4A,RASSF8,CTGF,SH3BP1,ABCA2,CD9,F2R,NAGA,RHOA,BLVRA,ALDH3B1,PRCP,PPM1H,INPP4B,IRF7,LTA4H,EHD1,CD33 |
| 2.579e-03 | -5.96 | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | 193 | 32 | 17758 | 1761 |
LASP1,UGT8,CPEB4,AK7,CAST,PYROXD2,TAP1,HERC6,DENND2D,SPTB,DTX3L,E2F7,ADD3,ADORA1,LHX6,FUT1,ABCD1,ALS2CL,REC8,RGMB,SYNE2,LITAF,TMEM151A,KDM4D,FAAH,MAP2,NLRC5,CMPK2,IFIH1,TRAF5,PRR15,ABCA1 |
| 2.579e-03 | -5.96 | GSE14308_TH1_VS_TH17_UP | MSigDB lists | GSE14308_TH1_VS_TH17_UP | 193 | 32 | 17758 | 1761 |
SLC35D2,IGFBP6,ST14,TMEM41B,KIF23,KCTD12,PSME1,MESDC2,CCDC92,KCNN4,ZFP36,KIF14,TMEM51,SORL1,TRIM21,TMEM37,SPRY2,NEB,FADS2,GUSB,MRS2,XRCC6BP1,DGKH,HPSE,CSF1,MLKL,ZMIZ1,ICOSLG,UBE2C,COBL,E2F8,NIPA1 |
| 2.579e-03 | -5.96 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 193 | 32 | 17758 | 1761 |
LZTFL1,FOXM1,CKAP2,ITPR2,STIL,CENPN,TSPAN7,FANCI,PPP4R1,OPN3,NEK2,ALDH7A1,BUB1,RFX5,BTBD3,CKS2,HES1,ALDH2,TIMP2,ZWINT,PBK,CDC20,ACO1,UBE2A,GALNT7,ICMT,FAM64A,PELI2,PGRMC1,AURKA,DONSON,UBE2C |
| 2.580e-03 | -5.96 | negative regulation of small GTPase mediated signal transduction | biological process | GO:0051058 | 42 | 11 | 16441 | 1675 |
ARHGAP24,TIMP2,ARAP3,ITGA3,RASA2,BCL6,STMN3,DAB2IP,SPRY2,RASA1,ARHGAP35 |
| 2.580e-03 | -5.96 | morphogenesis of an epithelial sheet | biological process | GO:0002011 | 42 | 11 | 16441 | 1675 |
ARHGAP24,RHOA,CYR61,ACVRL1,MEGF8,FLRT3,MPP5,DDR1,DAG1,HOXB2,DVL2 |
| 2.586e-03 | -5.96 | TMOD1 (tropomodulin 1) | protein interactions | 7111 | 19 | 7 | 16036 | 1726 |
MYO5B,PRKAA2,EFHD2,LRRFIP2,TBC1D4,NEB,NIN |
| 2.592e-03 | -5.96 | Hormone_recep | pfam domains | PF00104 | 48 | 12 | 16629 | 1696 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.597e-03 | -5.95 | negative regulation of protein localization to nucleus | biological process | GO:1900181 | 67 | 15 | 16441 | 1675 |
NOV,NFKBIE,THRA,BMP7,CABP1,NFKBIA,LITAF,RAB23,PSMD10,DAB2IP,MDFIC,APC2,PKIA,MDFI,CHP1 |
| 2.598e-03 | -5.95 | skeletal system morphogenesis | biological process | GO:0048705 | 211 | 35 | 16441 | 1675 |
RUNX2,GRHL2,HSPG2,HOXB7,THRA,SOX9,RAB23,TGFBR1,OSR2,FAM101B,DHRS3,HOXB2,SIX4,SGPL1,CTGF,IMPAD1,BMP7,MEGF8,DLG1,TFAP2A,TWIST1,TIPARP,SP5,MDFI,CYP26B1,SPEF2,FMN1,PRKRA,ZFAND5,GNAS,FGFR2,COL13A1,BMP1,OSR1,RARG |
| 2.605e-03 | -5.95 | central_nervous_system-brain-glioma-subependymoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-subependymoma_Grade_I | 7 | 4 | 17775 | 1757 |
NF2,IDH1,PTEN,TP53 |
| 2.605e-03 | -5.95 | subependymoma_Grade_I | COSMIC cancer mutations | subependymoma_Grade_I | 7 | 4 | 17775 | 1757 |
NF2,IDH1,PTEN,TP53 |
| 2.605e-03 | -5.95 | cervix-carcinoma-endometrioid_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endometrioid_adenocarcinoma | 7 | 4 | 17775 | 1757 |
GNAS,PTEN,PIK3CA,TP53 |
| 2.615e-03 | -5.95 | activation of immune response | biological process | GO:0002253 | 435 | 63 | 16441 | 1675 |
DDX58,THEMIS2,INPP5D,RPS6KA1,PSME2,CALM3,BTN3A1,PSMD10,PSME1,ITPR2,TEC,NCKAP1,PRKACA,CACNB4,CALM2,PSMD1,RPS6KA2,PIK3AP1,ELMO2,PTEN,PLCG2,PIK3CA,BAX,MAPK11,PDE4D,PIK3CD,SCARA3,LGMN,CNPY3,SYK,CD55,RIPK2,TNIP1,PSMB4,ITCH,MICB,CALM1,PIK3R1,RGCC,CR2,PRKCQ,YES1,ITPR3,DUSP4,ELK1,FOS,BCAR1,PSMA4,GPLD1,MAPKAPK2,CTSL,PLCG1,PTPRJ,PELI2,LIMK1,ITPR1,NFKBIA,NR4A3,NOD2,IRF7,ARPC2,IFIH1,TMEM173 |
| 2.617e-03 | -5.95 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2302 | 266 | 17775 | 1757 |
ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,RET,PPFIBP2,SYTL4,PLXNA1,CA8,SLC9A7,CYP1A1,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,POR,COL12A1,AHRR,PLCG1,DNM1L,ATP7B,PRDM5,FAM110C,TANC2,TRAF5,GAB1,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,FAM21C,MECOM,RALGPS2,FRY,FAM189A1,BDH1,PRKG1,MAP3K9,SORL1,CADPS2,CACNA1D,RIMS2,MCCC2,PAQR7,EPB41L5,STAT4,GNA11,AP1AR,SLCO4A1,PLEKHH2,PRKAG2,FAAH,PCDH19,IFIH1,XDH,ADAMTS16,PLA2G4A,TCTN2,IQGAP1,PKP2,RNF182,GRK6,CD274,APC2,TNFSF9,ZNF385B,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,COG2,PTPN9,SYNE2,UTRN,ITPR3,ALCAM,TRIQK,ATP10D,CMTM7,NIN,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,DENND5B,EPS8,DNAH3,SRPX2,HOXB2,TMEM87B,ITGB8,ANKS1B,PTEN,ARSG,FUT8,ATP8B1,FAM102A,TRIM62,NCOA2,PDGFC,ARHGEF28,MRS2,PIK3R1,DIAPH2,C2orf69,AIF1L,SNTB1,GALNT3,FGFR2,PPM1H,GRIN2D,ITGAV,USF2,ARSB,ESPL1,JARID2,RGMA,LTBP1,ARFGEF1,NENF,MPP5,TEX2,ITPR2,DNER,CACNB4,NUP62CL,TMC1,KREMEN1,NKAIN3,SIPA1L2,HSF2,SHC3,ANKFN1,PHTF1,SLC44A1,PAPSS1,TRPC1,POF1B,ANO4,TRAM1,MYRIP,ZNF462,CR2,IDH1,ADRBK2,DZIP1L,KCNMB4,HPSE,MAP2,HOXA9,EPB41L4A,CPPED1,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,TNS3,DAZAP1,IGF1R,FRAS1,MDFIC,LIMCH1,PIM1,ZRANB1,ALDH3A2,CHSY3,CORO2A,MGAT4B,PDE5A,EIF2AK1,SCRIB,HEATR5A,MFSD7,GNAS,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,GAS2L1,LMO7,NCKAP5,XYLT1,TP53,PDIA5,ERBB2,SLC25A48,CDH3,DIXDC1,NOTCH3,CPD,CLCN3,TMTC1,AKT1,PTPRU,SLC39A8,DUSP4,DOCK5,FANCE,DNAJC10,PTPRJ,ABHD12,C19orf66,TLE1,EFNA5,SPTBN5,CYP2U1,LTA4H,COL9A3,GOLIM4,PACSIN2,CDH22,ARHGEF11,LRP4,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,MLPH,BMP7,TOX2,KIAA0319,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,GCLC,DEPDC4,RC3H2,MAML2,FNDC3A,ARHGAP24,BANK1,RAP2C,UACA,CLIP4,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 2.625e-03 | -5.94 | CH | pfam domains | PF00307 | 67 | 15 | 16629 | 1696 |
LMO7,GAS2L1,SMTNL2,ASPM,IQGAP1,SYNE2,UTRN,CLMN,SPTBN5,DIXDC1,LIMCH1,TAGLN2,IQGAP3,SPTB,PLS3 |
| 2.625e-03 | -5.94 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 201 | 33 | 17758 | 1761 |
BCAM,PPP1R2,SERPINE2,ITGA6,TP53,PSMD10,TRIB2,C11orf95,SAC3D1,SLC25A36,EPCAM,MARCH8,PDGFA,PAPSS1,DRAM1,MINPP1,CKAP4,SEPHS1,SOCS5,CPD,TACC1,ADCK3,RC3H2,CBX6,UTRN,LRRC1,ALCAM,DCP2,NCOA3,WFS1,CLMN,HSPB1,JARID2 |
| 2.626e-03 | -5.94 | cell proliferation | biological process | GO:0008283 | 679 | 92 | 16441 | 1675 |
TXN,NF2,GRHL2,DLGAP5,LGR4,IL15RA,IL15,RPS6KA1,TP53,ERBB2,OSR2,BCL2L1,STIL,APC2,EMP2,TNFSF9,CCND1,NOV,CYP1A1,ARTN,CTGF,KIF14,ELF5,DLG1,IRF2,TWIST1,TACSTD2,DIXDC1,TSPAN1,DVL2,LAMP3,CKS2,PLK1,RIPK2,AKT1,FIGNL1,CR2,TFAP2C,IGSF8,LOXL2,CD40,EDNRA,IRS2,NRG1,F2RL1,E2F8,GAB1,GRN,BIN1,NKX3-1,POC1B,SOX9,EPS8,BTN3A1,GSTP1,TEAD3,FZD6,MECOM,DAZAP1,CYR61,PTEN,BMP7,BHLHE41,BAX,BUB1,CD70,PIM1,CITED2,WNT3A,SYK,RASGRF1,TACC1,SALL4,STAT4,ASPM,RC3H2,FURIN,SCRIB,BCAR1,C3orf58,CDK5R1,PITX2,FGFR2,ACVRL1,CSF1,ABCB1,NR4A3,FAM83D,NDE1,OSR1,NCAPG2,MELK |
| 2.630e-03 | -5.94 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 163 | 28 | 17775 | 1757 |
CD99,SPRED1,LZTFL1,IL15,NR3C1,HAL,OGDHL,TP53,MYBL2,COL18A1,TCF7,YES1,SESN1,DDR1,PRDM11,ARHGAP24,RPS6KA2,MUC4,CTGF,JAK1,SHROOM3,PTEN,STEAP2,PIM1,JAK3,NR3C2,SYK,CAPN1 |
| 2.637e-03 | -5.94 | SUN_dom | interpro domains | IPR012919 | 7 | 4 | 18293 | 1814 |
SUN1,SUN2,SUN3,SUCO |
| 2.637e-03 | -5.94 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN | 7 | 4 | 17758 | 1761 |
TLE1,TRIM8,CAST,SOX9 |
| 2.637e-03 | -5.94 | BUSA_SAM68_TARGETS_UP | MSigDB lists | BUSA_SAM68_TARGETS_UP | 7 | 4 | 17758 | 1761 |
CCND1,MAPK11,NR3C1,NR4A1 |
| 2.637e-03 | -5.94 | SCHRAMM_INHBA_TARGETS_UP | MSigDB lists | SCHRAMM_INHBA_TARGETS_UP | 7 | 4 | 17758 | 1761 |
CCND1,DUSP4,LMO4,BAX |
| 2.638e-03 | -5.94 | protein localization to lysosome | biological process | GO:0061462 | 20 | 7 | 16441 | 1675 |
SNX16,SORL1,ZFYVE16,SCARB2,RNF128,GNPTAB,SH3BP4 |
| 2.640e-03 | -5.94 | Pointed_dom | interpro domains | IPR003118 | 11 | 5 | 18293 | 1814 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 2.640e-03 | -5.94 | WHITESIDE_CISPLATIN_RESISTANCE_UP | MSigDB lists | WHITESIDE_CISPLATIN_RESISTANCE_UP | 11 | 5 | 17758 | 1761 |
MX1,GDF15,ERBB3,ITGA7,PTGES |
| 2.640e-03 | -5.94 | MODULE_293 | MSigDB lists | MODULE_293 | 11 | 5 | 17758 | 1761 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 2.640e-03 | -5.94 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | MSigDB lists | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | 11 | 5 | 17758 | 1761 |
CALM2,CALM3,DLG3,CALM1,DLG1 |
| 2.640e-03 | -5.94 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | MSigDB lists | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | 11 | 5 | 17758 | 1761 |
ERBB2,NRG2,NRG1,ERBB3,AKT1 |
| 2.645e-03 | -5.93 | - | gene3d domains | 3.40.309.10 | 19 | 7 | 9988 | 1080 |
ALDH7A1,ALDH3B1,ALDH2,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.645e-03 | -5.93 | - | gene3d domains | 3.40.605.10 | 19 | 7 | 9988 | 1080 |
ALDH7A1,ALDH3B1,ALDH2,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.653e-03 | -5.93 | MODULE_198 | MSigDB lists | MODULE_198 | 297 | 45 | 17758 | 1761 |
CCNE2,FOXM1,SOX9,PTTG1,NDC80,KIF23,PSMD10,CCNB1,BARD1,PHLDA1,RAD23A,TOP2A,CDKN2C,APLP2,WEE1,HSF2,NEK2,GTF2F2,TFAP2A,BUB1,RFX5,MYT1,PLK1,TGIF1,ZWINT,CENPA,AKT1,BCL9,UBE2A,MYBL2,RUNX3,GTF2A2,FOS,CDK1,PSMA4,PRIM1,MAP2,HNRNPH2,DCK,STK38,HDAC1,TLE1,CENPE,CCNB2,ESPL1 |
| 2.653e-03 | -5.93 | positive regulation of transcription from RNA polymerase II promoter | biological process | GO:0045944 | 1009 | 130 | 16441 | 1675 |
EPAS1,HEXB,MORF4L2,EPCAM,HSF2,GRHL1,NPNT,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TNIP1,NFE2L1,TFAP2C,LDB2,ARF4,AHRR,KLF12,NOD2,HDAC1,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,GATA2,MYDGF,WNT3A,ELK3,SALL4,STAT4,MYBL2,ELK1,NFIB,NCOA3,ONECUT1,ETS2,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,GRHL2,ARMCX3,FOXM1,RPS6KA1,THRA,TP53,OSR2,LPIN3,SS18,LMO4,TWIST1,DAB2IP,NOTCH3,ETV4,SIRT1,AKT1,RIPK2,FOXJ2,PYGO1,GTF2A2,CD40,NFIX,JADE1,RBL1,NRG1,IRF7,KLF5,GLIS3,NKX3-1,CKAP2,PBX3,HMGN3,ETS1,SIX4,TEAD3,WWP2,TOP2A,IRF2BPL,E2F7,BMP7,TOX2,TFAP2A,GTF2F2,CITED2,NCOA2,HES1,PLSCR1,NR3C1,NR4A1,BCL9,PIK3R1,RGCC,PPARA,GRIN1,MAML2,YES1,FOS,PITX2,ACVRL1,FGFR2,NR4A3,ARRB1,HMGA1,GPER1,FZD5,OSR1,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 2.654e-03 | -5.93 | ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 140 | 25 | 17758 | 1761 |
SORBS1,REPS2,CDKN1C,AKT1,PTPRU,RGMB,EPS8,PIK3R1,ERBB2,TGFBR1,GDF15,ERBB2IP,ROR1,BCAR1,ZFYVE9,PTPRF,PTPRJ,IGF1R,SHC3,ACVRL1,LTBP2,ERBB3,CITED2,GAB1,FRS3 |
| 2.656e-03 | -5.93 | epithelial cell development | biological process | GO:0002064 | 196 | 33 | 16441 | 1675 |
EXPH5,GRHL2,ST14,FRMD6,IQGAP1,SOX9,COL18A1,F11R,SDC1,PDGFB,TMC1,CST3,PDE4D,EPB41L5,RAPGEF2,TFAP2C,EZR,SCRIB,FNDC3A,FZD7,ARHGEF26,ONECUT1,BFSP1,FGFR2,SHROOM3,SPINT2,RAP2C,KLF5,HOXB13,SOX8,PLOD3,F2RL1,RARG |
| 2.680e-03 | -5.92 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 178 | 30 | 17758 | 1761 |
ARHGAP11A,FADS2,COL9A3,SHMT1,ZNF395,TSC22D3,MICB,EPS8,CXorf57,SLC7A2,TRMT2B,SAV1,PHLPP1,PSIP1,FZD6,FANCI,H1FX,APOBEC3B,ALDH5A1,HOXA9,PTER,ALDH1A3,PLK4,ARRB1,IGFBP2,LMAN1,NRGN,SPRY2,E2F8,SMAGP |
| 2.680e-03 | -5.92 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | 178 | 30 | 17758 | 1761 |
GCA,TGIF1,MBP,PPP1R2,PLSCR1,TTC7A,TDRKH,LACTB2,IFIT3,BMP2K,SYTL2,FAS,PDGFA,OTUD1,SPIN4,ITPR1,PASK,TOX2,TMEM51,PGM2L1,SGK1,CCDC82,ARRB1,MDFIC,HS3ST3B1,RELL1,PDE4D,CNOT6L,F2RL1,CLIP2 |
| 2.691e-03 | -5.92 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 154 | 27 | 17570 | 1756 |
IQGAP1,RASA2,EZR,TEC,YES1,CACNB4,SPTB,GNA11,RASA1,GNAS,JAK1,CDH1,PTEN,SNX18,CDK16,CABP1,DLG1,ARRB1,DAB2IP,GEM,JAK3,TRAF5,TIAM1,SYK,GM2A,S100A6,ESYT2 |
| 2.693e-03 | -5.92 | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 217 | 35 | 17758 | 1761 |
RMND5A,FRMD6,PYROXD2,CUL4B,COL4A5,DPP8,ARHGEF40,SYTL2,ABCD4,MECOM,CCND1,IGF1R,BMP7,PLCG2,SORL1,DAB2IP,RFX5,PDE4D,LGMN,PTPRE,MAST4,SPRY2,FARP2,COL7A1,MRPS36,CASP4,STX3,DGKH,NEIL1,RND3,MADD,ERAP1,TMEM120A,UNC5B,ABCG1 |
| 2.709e-03 | -5.91 | MOOTHA_PGC | MSigDB lists | MOOTHA_PGC | 405 | 58 | 17758 | 1761 |
PCOLCE,SLC2A4,AVPI1,LRRFIP2,FOXM1,TMEM41B,NDRG2,AES,MPP5,GDF15,ITPR2,SLC20A1,PHLDA1,DNAJB9,SAC3D1,TYMP,CA2,MKRN3,ABCA2,ARVCF,TINAGL1,MANF,NCAM1,CDKN2D,S100A13,GPX4,CKS2,TRAK2,PGM1,SHMT1,PRSS23,FZD4,LPGAT1,PLEKHO1,SAT1,EIF2AK1,COL7A1,ATP1B1,ZFAND5,SLC25A5,FOS,SPTLC2,EDNRA,DPYSL3,NFIX,GABARAPL1,MAPKAPK2,CARHSP1,ATP1A1,SLC25A4,NGFRAP1,TIMM8A,P4HA2,DBI,CAB39,CDK18,ACOT7,EGLN1 |
| 2.711e-03 | -5.91 | ENGELMANN_CANCER_PROGENITORS_DN | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_DN | 69 | 15 | 17758 | 1761 |
REC8,LRRFIP2,CTGF,CITED4,CORO2A,BMP7,SYBU,FAM102A,SGK1,SLC35C1,KLK6,SYTL4,FBXO27,PTGFRN,OSGIN1 |
| 2.711e-03 | -5.91 | chr9q22 | MSigDB lists | chr9q22 | 69 | 15 | 17758 | 1761 |
SUSD3,SLC35D2,ANKS6,SEC61B,SHC3,SEMA4D,CORO2A,GALNT12,ZNF367,HABP4,NR4A3,TGFBR1,EPB41L4B,SYK,CKS2 |
| 2.715e-03 | -5.91 | V$SMAD3_Q6 | MSigDB lists | V$SMAD3_Q6 | 225 | 36 | 17758 | 1761 |
LTBP1,MRC2,MORF4L2,CRABP2,TEAD3,IL17RB,ST5,ANKS6,FRY,ANKS1B,BHLHE41,LHX6,SERINC2,RFX5,PDE4D,ZRANB1,MYT1,BTBD3,PLEKHA6,PELI3,SAV1,RNF19B,NIN,TMEM164,ARHGEF19,PLEKHH2,SYT7,MAP2,H1F0,FAM117A,GRIN2D,ANXA9,RUSC1,KLF7,DOCK9,JARID2 |
| 2.715e-03 | -5.91 | microtubule organizing center attachment site | cellular component | GO:0034992 | 7 | 4 | 17570 | 1756 |
SUN1,SUN3,SUN2,SYNE2 |
| 2.715e-03 | -5.91 | LINC complex | cellular component | GO:0034993 | 7 | 4 | 17570 | 1756 |
SUN1,SUN3,SUN2,SYNE2 |
| 2.724e-03 | -5.91 | LU_EZH2_TARGETS_DN | MSigDB lists | LU_EZH2_TARGETS_DN | 355 | 52 | 17758 | 1761 |
PAPSS2,FAM169A,ALDH6A1,POC1B,PM20D2,ETS1,STIL,SCML1,RPS6KA2,CTGF,ALPP,CALD1,EXOC8,LIMCH1,HYLS1,FAR2,PTPRE,SGCB,GAD1,NR2C1,MCCC2,ATP2B1,IGSF3,NFE2L3,GFPT1,TBC1D8B,TACC1,PBK,BCL9,NBPF3,LITAF,ACO1,ANLN,ASB13,ANTXR1,C3orf58,CDK5R1,DCP2,GLCE,CNTNAP1,IRS2,CACHD1,CDKN2AIPNL,RAB11FIP2,PHLPP2,AXL,LRIG1,RAB11FIP1,FAM83D,ADIPOR1,NFKBIZ,CMTM4 |
| 2.734e-03 | -5.90 | platelet dense tubular network | cellular component | GO:0031094 | 11 | 5 | 17570 | 1756 |
ITPR2,ITPR3,F2R,ITPR1,EHD1 |
| 2.734e-03 | -5.90 | MHC class I protein complex | cellular component | GO:0042612 | 11 | 5 | 17570 | 1756 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 2.735e-03 | -5.90 | RGAANNTTC_V$HSF1_01 | MSigDB lists | RGAANNTTC_V$HSF1_01 | 422 | 60 | 17758 | 1761 |
IER5L,SLC2A4,ARMCX3,TRIP10,CACNA2D2,PSMD10,COL4A5,ISYNA1,MORF4L2,OSR2,VASH1,BCAP31,SIX4,ATG4A,IRF2BPL,FOXP2,CYP1A1,SHC3,TSPAN6,IL6ST,CD9,DAPK1,BCL6,ADAM15,ABCD1,MDFIC,WWP1,TSPAN13,CACNA1D,PIKFYVE,RASGEF1A,GAD1,RIMS2,ADAMTS2,HES1,FBLN5,ELK3,BCL9,RGAG1,LHFPL2,SP4,RASGRP2,GNAS,HLA-B,CACHD1,POPDC3,MAP2,COL13A1,SCG2,DBI,NETO2,NR4A3,NR4A2,ATP1B3,FHL1,SEMA3A,HSPB1,CMTM4,ACOT7,EHD1 |
| 2.738e-03 | -5.90 | V$NFY_01 | MSigDB lists | V$NFY_01 | 241 | 38 | 17758 | 1761 |
GRHL2,CIT,SLC25A13,ETV5,SLC25A27,PDIA3,DNAJB11,KIF23,NANS,SLC20A1,CYP39A1,M6PR,CDH1,SHC3,RGS3,FUT8,PASK,NEK2,TSPAN13,GLB1L2,SELK,RPN2,KLF9,NCAM1,DLG3,CKS2,PLK1,HES1,ADCK3,COQ10B,LDB2,CDK1,PRCP,PRDM5,AGFG2,KLF11,HOXB13,JARID2 |
| 2.739e-03 | -5.90 | regulation of nucleocytoplasmic transport | biological process | GO:0046822 | 204 | 34 | 16441 | 1675 |
DDX58,TXN,NFKBIE,THRA,RAB23,PSMD10,TGFBR1,IL18,PRKACA,BARD1,APC2,IL18R1,IER3,NOV,CDH1,SP100,DACT1,BMP7,CABP1,DAB2IP,MDFIC,WNT3A,MDFI,CHP1,SIRT1,RHOA,PIK3R1,LITAF,PRKCQ,FZD7,NFKBIA,INPP4B,PKIA,TMEM173 |
| 2.740e-03 | -5.90 | V$OCT1_01 | MSigDB lists | V$OCT1_01 | 249 | 39 | 17758 | 1761 |
THRA,HPCAL4,PPP2R3A,HDAC9,CCND1,SESN3,PTEN,CYR61,LLGL2,LMO4,LHX6,MITF,PRKG1,TSPAN13,PDE4D,EGLN3,CITED2,DGKG,CPD,PCDH1,PLEKHA6,ING1,FZD4,SH3BGRL,SERTAD4,KIF13A,PYGO1,ITPR3,TP53INP2,NIN,NFIX,CXXC4,KLF12,RHOBTB2,FAM117A,SP6,CEP41,JARID2,NXT2 |
| 2.742e-03 | -5.90 | - | gene3d domains | 3.30.500.10 | 24 | 8 | 9988 | 1080 |
HLA-B,MICB,HLA-F,HLA-E,RAET1L,HLA-C,ULBP2,HLA-A |
| 2.746e-03 | -5.90 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | 186 | 31 | 17758 | 1761 |
SUN2,ACACB,ZNF395,TSC22D3,XYLT1,EPHA4,TMX4,ARL4C,GRIN1,PTGER4,BTN3A1,CR2,SLC7A2,TRIB2,FOS,FAM46C,DNAJB9,RASGRP2,IRS2,MARCH8,ADD3,DTX4,SORL1,SGK1,NR4A2,SEMA3G,PTPRE,MYBL1,TRAM1,NR3C2,TOB1 |
| 2.746e-03 | -5.90 | GSE27786_LSK_VS_BCELL_UP | MSigDB lists | GSE27786_LSK_VS_BCELL_UP | 186 | 31 | 17758 | 1761 |
ENPP4,CASP3,SLC25A24,SHMT1,MCTP1,CAMKK1,CCDC34,CCNF,HDAC6,AIFM2,SPNS3,MUM1L1,ZDHHC21,PRIM1,MESDC2,AMZ2,DNAJC10,PVRL2,BHLHB9,PAPSS1,MATN2,ABCA2,ARRB1,ECI2,PRKCDBP,MLKL,OAS3,IQGAP3,PLCB2,NAGA,FARP2 |
| 2.746e-03 | -5.90 | GSE3982_DC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_DN | 186 | 31 | 17758 | 1761 |
ANXA3,ARAP3,RHOA,REPS2,FOXJ2,SYNE2,SNN,SPTLC2,RNF19B,STK17B,IL18R1,CYP4F3,STX3,ARHGAP35,MFAP3L,PPP2R5A,ETS2,TRANK1,JAK1,PTEN,NMI,KLF3,ZNF165,FAM117A,ALPK3,IRF7,DLG3,CDKN2D,SYK,CTDSP2,CKAP4 |
| 2.750e-03 | -5.90 | lung-carcinoma-acinar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-acinar_adenocarcinoma | 26 | 8 | 17775 | 1757 |
KIF5B,AKT1,FGFR2,PTEN,SDC4,PIK3CA,TP53,ERBB2 |
| 2.756e-03 | -5.89 | HLA-C (major histocompatibility complex, class I, C) | protein interactions | 3107 | 64 | 15 | 16036 | 1726 |
HLA-B,TAPBP,TCTN2,HLA-E,TMEM30A,HLA-F,ITGA6,NETO2,FAM213A,HLA-C,FBXO6,ATP1B3,POMGNT1,PRRG4,HLA-A |
| 2.765e-03 | -5.89 | Ras signaling pathway | KEGG pathways | hsa04014 | 227 | 39 | 6908 | 758 |
PLA2G4A,RALBP1,RASA2,CALM3,MRAS,BCL2L1,PDGFB,ETS1,PRKACA,FGF19,CALM2,PDGFA,IGF1R,GNB5,SHC3,PLCG2,PIK3CA,PIK3CD,TIAM1,RASGRP1,RASGRF1,PDGFC,RHOA,AKT1,PIK3R1,CALM1,GRIN1,ELK1,RASA1,RASGRP2,PGF,PLCG1,ETS2,FGFR2,CSF1,EFNA5,PLD1,ARF6,GAB1 |
| 2.768e-03 | -5.89 | ERBB3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 2065 | 83 | 18 | 16036 | 1726 |
AKT1,CD82,PIK3R1,NRG2,ERBB2,HDAC6,HLA-A,RASA1,BCAR3,TNS3,PLCG1,SHC3,IL6ST,LRIG1,NRG1,ERBB3,JAK3,SYK |
| 2.770e-03 | -5.89 | AMIT_SERUM_RESPONSE_240_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_240_MCF10A | 56 | 13 | 17758 | 1761 |
PRSS8,ARHGEF3,PRKAG2,B3GNT2,CDKN1C,CDH1,PVRL2,ALDH1A3,PKP2,EZR,BCL2L1,B4GALT4,OCLN |
| 2.770e-03 | -5.89 | MODULE_57 | MSigDB lists | MODULE_57 | 56 | 13 | 17758 | 1761 |
CCNE2,PLK1,WEE1,PTTG1,CDC20,TP53,HDAC1,BUB1,PKMYT1,CCNB1,CCNB2,CDK1,ESPL1 |
| 2.770e-03 | -5.89 | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 56 | 13 | 17758 | 1761 |
BANK1,FUT8,TCF7,CNTNAP2,ATP1B1,NUCB2,MYBL1,DGKG,ALCAM,ATP10D,ABCA1,ATP2B1,SOCS5 |
| 2.770e-03 | -5.89 | KORKOLA_YOLK_SAC_TUMOR | MSigDB lists | KORKOLA_YOLK_SAC_TUMOR | 56 | 13 | 17758 | 1761 |
MDK,SMARCA2,CEP70,METTL7A,VANGL1,FRAS1,FLRT3,NMI,NEK2,NRG1,FZD5,B4GALT4,CYP26A1 |
| 2.772e-03 | -5.89 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 347 | 51 | 17758 | 1761 |
GRN,SORT1,PEX6,TRIP10,TSPAN15,FXYD3,ESRP1,PDIA5,COL18A1,KCTD12,POMGNT1,CCNB1,MERTK,DDR1,LGALS3BP,FZD6,PARM1,NEO1,IER3,SNTA1,KIAA1107,KCNN4,IMPAD1,OPN3,ERBB3,EPHB4,SLC16A5,XKR8,WBP5,COL6A2,RIPK2,CELSR2,MPP1,SCRIB,ATP1B1,C15orf39,CD40,SNTB1,GNA11,MFSD7,CYB5A,CRISPLD2,ALDH5A1,H1F0,NGFRAP1,PITPNA,PIEZO1,WDR62,NCAPG2,CCNB2,XDH |
| 2.772e-03 | -5.89 | epithelium migration | biological process | GO:0090132 | 74 | 16 | 16441 | 1675 |
GRHL2,NR4A1,TGFBR1,LOXL2,PKN1,ANLN,EMP2,S100A2,GPLD1,NOV,PTEN,SCG2,PIK3CA,EPHB4,ARSB,CYP1B1 |
| 2.773e-03 | -5.89 | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | 133 | 24 | 17758 | 1761 |
NFE2L3,LTBP1,NKX3-1,HOXB7,VANGL1,PBX3,COL4A5,RAB38,SEPP1,HOXB2,LMNA,FZD7,DPYSL3,SGPL1,GATA2,NGFRAP1,HOXA9,LRIG1,RRBP1,DRAM1,IGFBP2,SNX10,SCYL3,WBP5 |
| 2.776e-03 | -5.89 | regulation of cell morphogenesis involved in differentiation | biological process | GO:0010769 | 322 | 49 | 16441 | 1675 |
SEMA6B,SSH1,CIT,EPHA4,RET,LRP4,TGFBR1,PLXNA1,CRABP2,FBLN1,FAM21C,PTEN,MEGF8,DPYSL2,KIF13B,VASN,DAB2IP,TACSTD2,TNFRSF12A,TWIST1,SEMA3G,CTTN,WNT3A,TIAM1,TRIM62,SEMA3B,EPB41L5,SSH3,RHOA,MFI2,RAPGEF2,GRIN1,RGCC,DAG1,CDK5R1,AP1AR,SEMA4D,BHLHB9,LIMK1,CORO1C,SIPA1L1,TRIOBP,EFNA5,NRG1,ARPC2,ITPKA,SEMA3A,LZTS1,L1CAM |
| 2.790e-03 | -5.88 | lysosomal transport | biological process | GO:0007041 | 61 | 14 | 16441 | 1675 |
LAMP1,ZFYVE16,MTM1,SCARB2,SORT1,GNPTAB,SORL1,SNX16,SPTBN5,KIF13A,ARSB,HOOK1,HMGXB4,M6PR |
| 2.801e-03 | -5.88 | REACTOME_CELL_CYCLE_MITOTIC | MSigDB lists | REACTOME_CELL_CYCLE_MITOTIC | 306 | 46 | 17758 | 1761 |
CCNE2,SPC25,CEP70,PSME2,CENPI,PTTG1,NDC80,CDCA8,KIF23,PSMD10,NUF2,PSME1,CCNB1,PRKACA,CENPN,CCND1,CDKN2C,WEE1,PSMD1,CNTRL,NEK2,PLK4,CDKN1B,TUBG1,BUB1,CDKN2D,NUP85,PLK1,ZWINT,CENPA,PSMB4,KIF20A,CDC20,MYBL2,PRKAR2B,PKMYT1,CDK1,PSMA4,PRIM1,PPP2R5A,RBL1,HDAC1,AURKA,CEP41,UBE2C,CCNB2 |
| 2.802e-03 | -5.88 | transferase activity | molecular function | GO:0016740 | 2220 | 263 | 16491 | 1673 |
AK7,RET,HEXB,FBXO2,NANS,CAMK1D,OAT,CCNB1,PJA2,BARD1,DAPK2,WEE1,TYMP,UBE2T,PIK3CA,FUT1,PIK3CD,MARCH2,TIPARP,SMYD5,MGAT5,TMEM68,FBXL16,ACVR1C,PBK,GALNT7,ICMT,RNF19B,PRIM1,PIAS3,GNPTAB,LIMK1,PLK2,PRDM5,WBSCR27,ITPKA,TRAF5,CDK17,NUAK1,DGKQ,SOX9,HERC6,MERTK,BMP2K,RABGGTA,MARCH8,ZNRF2,TPST1,DAPK1,NEK2,MAP3K9,PRKG1,ADCK2,ALPK1,PIKFYVE,DGKG,MYLIP,MAST4,GFPT1,B3GNT7,DDB2,MMD,ADCK3,LPGAT1,PIP4K2C,EPHA1,SPTLC2,GLT8D2,STK17A,DGKH,NCOA3,PRKAG2,DCK,CSNK1G1,SETD3,AURKA,STK39,CDK18,MAP3K5,NRBP1,PAPSS2,GALNT12,RPS6KA1,TESK2,RNF182,GRK6,MGST2,PRKACA,DDR1,CDS1,CCND1,RNF220,XYLT2,EPHB4,DLG3,PHKA2,SULT2B1,RIPK2,SAT1,PANK1,PRKCQ,PKMYT1,XRCC6BP1,PRDM11,EPHA10,DDOST,JAK1,CDK19,STK26,AXL,HS3ST3B1,MLKL,SLC27A3,MAPK12,HERC5,FBXO6,PKN1,GSTP1,WWP2,DTX3L,FUT2,RNF128,MGAT4A,ALG13,FUT8,FAM20B,SGK3,MAPK11,WWP1,ERBB3,TRIM62,NCOA2,PARP9,B3GNT2,SHMT1,MPP1,ELOVL3,PARP4,UBE2A,FBXO9,AK4,C1GALT1C1,YES1,GALNT3,CDK5RAP1,FGFR2,ACVRL1,RYK,PGM2L1,LRRK1,CMPK2,MELK,OCLN,NMRK1,LTBP1,TRIM2,UGT8,CAMKK1,CPT2,EPHA4,CUL4B,MGAT5B,TRIM68,CHPF,RPS6KA2,METTL7A,PAPSS1,PASK,DLG1,PLK1,ITCH,ROR1,STK17B,ADRBK2,CDK1,TRIM9,HS6ST1,AGPAT2,PIK3C2B,PRKAA2,LMTK3,PARP12,ADCK5,TEC,B4GALT4,B4GALNT1,B3GALNT1,UBE2Q2,IGF1R,PIM1,CHSY3,TESK1,MGAT4B,GYLTL1B,STRADB,EIF2AK1,PDK3,PDIK1L,CDK5R1,G2E3,MAPKAPK2,UAP1,KBTBD2,PRPS2,ALPK3,ZDHHC7,JAK3,RNF146,LMO7,UGP2,XYLT1,ERBB2,KBTBD11,SETDB2,ZDHHC12,ZDHHC23,PLK4,GOT1,RPN2,OAS3,SCYL3,SEPHS1,SIRT1,MAP3K3,AKT1,MAP3K6,STK38,PTK7,PEX2,ST3GAL1,NDST3,CMAS,PINK1,KLHL13,CIT,GNE,TGFBR1,TRMT2B,POMGNT1,TRIB2,NRP2,ZDHHC21,ADRBK1,CDK16,A4GALT,UBE2J1,TRIM21,SGK1,BUB1,SYK,GCNT1,B3GALT6,AMFR,RC3H2,NADK2,DGKE,KLHL2,TRIM69,NAT1,ARRB1,PLOD3,UBE2C,HIPK3 |
| 2.802e-03 | -5.88 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | 194 | 32 | 17758 | 1761 |
SPRED1,LZTFL1,CPEB4,C5orf30,MIER3,KCTD12,PSME1,CD274,TNFSF9,FAM46A,FLRT3,MGAT4A,MITF,TMBIM6,MTMR11,OAS3,LRP11,TIAM1,XKR8,NUB1,FZD7,ABR,DCP2,NFIX,ARHGAP35,CD83,SEMA4D,NAT1,PTK7,TRIOBP,PLOD3,TRAF5 |
| 2.802e-03 | -5.88 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | 194 | 32 | 17758 | 1761 |
LTBP1,PAPSS2,NQO1,ATP9A,PPFIBP2,FAM134A,HES2,SPR,BMP2K,SGPL1,AKIRIN1,RPS6KA2,ST5,ADORA1,CA2,CNTRL,CRY2,NR2C1,TRAK2,MAP3K3,MX1,TIMP2,COL6A2,NFE2L1,BSDC1,NFIX,NCOA3,RPL12,NR1D2,PRDM5,USF2,ABCG1 |
| 2.802e-03 | -5.88 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 32 | 17758 | 1761 |
CMAS,ENO2,SPC25,ST14,PSME2,PTTG1,CDCA8,NDUFA4,BARD1,PSIP1,SAC3D1,TNS3,DPYSL2,ATP5H,BCL6,PDIA6,RASGRP1,SEPHS1,METAP2,HMMR,ALDH2,MRPS33,RAD17,GTF2A2,CCNF,ICMT,KIF11,H2AFV,PSMA4,FUCA1,MDH1,UBE2C |
| 2.802e-03 | -5.88 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_UP | 194 | 32 | 17758 | 1761 |
GRN,CHCHD7,MRPS15,HEBP1,TESK2,FAM198B,NANS,SEPP1,BCAP31,FAM111A,SCNN1A,BDH1,N4BP3,ABCA2,PLEKHF1,IRF2,ACOX2,TECR,MED22,MBP,MMD,GUSB,LPGAT1,OXR1,RAB38,ATP8B3,ANLN,CDK1,CARHSP1,SLC25A4,MDH1,CPPED1 |
| 2.802e-03 | -5.88 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | 194 | 32 | 17758 | 1761 |
IL15RA,PSME2,HLA-E,TAP1,PSME1,ISYNA1,CMTM6,LGALS3BP,RABGGTA,TYMP,TRIM21,HLA-C,ZRANB1,SMYD5,MX1,SEC23A,B3GNT2,USP18,SH3BGRL,SAT1,TAPBP,NCOA3,HLA-B,ATP1A1,NAT1,NMI,FAM117A,IRF7,PPP2R3C,CMPK2,IFIH1,NRBP1 |
| 2.802e-03 | -5.88 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | 194 | 32 | 17758 | 1761 |
SLC25A24,CCDC109B,GGA1,INPP5D,XYLT1,SELL,TGFBR1,TRMT2B,TRIB2,DDR1,TIPRL,SGPL1,FRYL,AIM1,PIK3CD,TPCN1,GCA,SMARCA2,ARAP2,MMD,CXorf57,CR2,PRIM1,CD83,ENDOD1,CDK19,UTP14C,ITPR1,DTX4,PIK3C2B,NR3C2,PKIA |
| 2.802e-03 | -5.88 | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | 194 | 32 | 17758 | 1761 |
CASP3,FBLIM1,SLC25A24,TXN,CPEB4,HJURP,BLVRB,PKN1,TEAD3,CYP26A1,CCDC92,PPP4R1,SGK3,SORL1,RAB20,TECR,SNX10,TRAK2,HMMR,MPP1,LPGAT1,BORA,RANBP9,ARHGEF26,IRS2,CARHSP1,DUOX1,RBL1,WIPI1,AXL,NETO2,AGFG2 |
| 2.802e-03 | -5.88 | GSE22886_TH1_VS_TH2_48H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_DN | 194 | 32 | 17758 | 1761 |
PLA2G4A,PARP12,UGP2,CHCHD7,HEXB,TIPRL,DNAJB9,IL17RB,MARCH8,ACAP2,PHTF1,RPN2,EGLN3,ZMYM1,KCNJ12,SH3BGRL,PIK3R1,PTGER4,PARP4,PRKCQ,SLC11A2,RASA1,FOXD2,ANKRD10,NCOA3,RBM47,GDE1,CDK19,LRIG1,INPP4B,CAB39,RGS14 |
| 2.802e-03 | -5.88 | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | 194 | 32 | 17758 | 1761 |
CMAS,SORT1,KIAA1462,SELL,MGAT5B,FAM101B,IL18R1,E2F7,LMO4,KLF3,PLEKHF1,SGK1,IFIT1,NOTCH3,SYTL3,GM2A,S100A6,PRODH,PQLC3,CORO2A,PDE5A,IGSF8,TRIM9,PITX2,ALDH3B1,PPP2R5A,DCK,TBX18,UACA,SERPINI1,SYT13,F2RL1 |
| 2.802e-03 | -5.88 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 194 | 32 | 17758 | 1761 |
PARP12,TSC22D3,RET,DDR1,TRIM68,FRY,AIM1,SRR,PIK3CD,PDE4D,PIKFYVE,SNX10,GCNT1,MAP3K3,TGIF1,GCA,SYBU,CR2,PRKAR2B,RASGRP2,CD83,KLHL2,PTPRJ,BANK1,ETS2,DTX4,RAB11FIP1,CLMN,TBC1D4,TRAF5,CBX7,OCLN |
| 2.807e-03 | -5.88 | BIOCARTA_BAD_PATHWAY | MSigDB lists | BIOCARTA_BAD_PATHWAY | 26 | 8 | 17758 | 1761 |
IGF1R,AKT1,RPS6KA1,PIK3R1,PIK3CA,BAX,PRKAR2B,BCL2L1 |
| 2.807e-03 | -5.88 | chr12q22 | MSigDB lists | chr12q22 | 26 | 8 | 17758 | 1761 |
HAL,NTN4,VEZT,NDUFA12,LTA4H,NR2C1,METAP2,TMCC3 |
| 2.807e-03 | -5.88 | PID_VEGFR1_PATHWAY | MSigDB lists | PID_VEGFR1_PATHWAY | 26 | 8 | 17758 | 1761 |
PGF,PLCG1,AKT1,PIK3R1,PIK3CA,PRKACA,NRP2,RASA1 |
| 2.811e-03 | -5.87 | MODULE_491 | MSigDB lists | MODULE_491 | 76 | 16 | 17758 | 1761 |
B3GALT6,LAMP2,SYPL1,PLSCR1,SLC25A13,TMX4,PARP4,ASAH1,TRIB2,DENND2D,FRMD4B,IRS2,ATP1A1,KCNN4,IRF2,PIKFYVE |
| 2.811e-03 | -5.87 | LINDVALL_IMMORTALIZED_BY_TERT_DN | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_DN | 76 | 16 | 17758 | 1761 |
ENO2,HSPG2,SAT1,ARL4C,LMCD1,LHFPL2,ANTXR1,LGALS3BP,PLOD2,CYR61,PTK7,LTBP2,PER3,ARL4D,PTGES,MDFI |
| 2.814e-03 | -5.87 | ETS | smart domains | SM00413 | 29 | 9 | 9131 | 997 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7,ELF3 |
| 2.817e-03 | -5.87 | MAVS (mitochondrial antiviral signaling protein) | protein interactions | 57506 | 58 | 14 | 16036 | 1726 |
DDX58,KCNIP3,RIPK2,TSPAN6,AMFR,ITCH,OTUB2,IRF7,OAS3,IFIT3,IFIH1,NDFIP1,TRAF5,TMEM173 |
| 2.818e-03 | -5.87 | REGULATION_OF_APOPTOSIS | MSigDB lists | REGULATION_OF_APOPTOSIS | 339 | 50 | 17758 | 1761 |
CASP3,DAP,TP53,BCL2L1,AIFM2,GSTP1,BARD1,ADAMTSL4,IER3,DAPK2,TOP2A,CDKN2C,CARD8,ADORA1,IGF1R,PTEN,SIVA1,BAX,BCL6,DAPK1,CDKN1B,CD70,PIM1,F2R,CDKN2D,MX1,ACVR1C,GCLC,CASP9,HTATIP2,GLO1,RUNX3,BCAR1,STK17B,CASP4,CDK1,RASA1,CDK5R1,FAS,SOCS3,STK17A,SCG2,SEMA4D,MADD,HDAC1,MAP3K5,AIFM3,HSPB1,IFI6,HIPK3 |
| 2.827e-03 | -5.87 | TRIM8 (tripartite motif containing 8) | protein interactions | 81603 | 52 | 13 | 16036 | 1726 |
TRIM9,PIAS3,PCGF5,TRIM8,TRIM2,PTEN,MKRN3,RC3H2,TP53,TRIM21,OTUB2,RNF113A,TRAF5 |
| 2.831e-03 | -5.87 | YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta) | protein interactions | 7533 | 158 | 29 | 16036 | 1726 |
MAP3K3,ING1,ARHGEF28,NR3C1,THRA,FRMD6,DCAF7,KIF23,SAV1,OPTN,PDIA4,RASSF8,KIF5B,NCOA3,CDK16,ZFP36,PIK3CA,KLC3,TUBG1,ARRB1,CDKN1B,ALDH7A1,MAP3K5,HSPB1,ISOC1,NCOA2,RIMS2,CCDC88A,USP43 |
| 2.841e-03 | -5.86 | XBP1(S) activates chaperone genes | REACTOME pathways | R-HSA-381038 | 53 | 13 | 8202 | 867 |
GFPT1,SEC61B,ADD1,WIPI1,WFS1,DNAJC3,PDIA5,DNAJB11,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 2.847e-03 | -5.86 | TTTGCAG,MIR-518A-2 | MSigDB lists | TTTGCAG,MIR-518A-2 | 202 | 33 | 17758 | 1761 |
ZMAT1,SORBS1,CPEB4,OSGIN2,MIER3,RAB6A,PJA2,SIPA1L2,DAPK1,BRI3,EPB41L4B,PACSIN1,LAMP2,MAP3K3,PCGF5,TIMP2,MMD,TACC1,SEPT6,ITCH,FAM133B,ZFAND5,PTGFRN,PTPRF,STK38,CORO1C,RAP2C,FAM117A,YOD1,GDF11,HMGA1,NR3C2,CPEB2 |
| 2.851e-03 | -5.86 | fn3 | pfam domains | PF00041 | 137 | 25 | 16629 | 1696 |
PTPRU,EPHA4,VWA1,COL7A1,IL27RA,EPHA1,FNDC3A,MERTK,COL12A1,NEO1,PTPRF,EPHA10,TRIM9,PTPRJ,IGSF9,AXL,IL6ST,IL31RA,ANKFN1,SORL1,EPHB4,NCAM1,L1CAM,LIFR,IGDCC4 |
| 2.858e-03 | -5.86 | regulation of innate immune response | biological process | GO:0045088 | 371 | 55 | 16441 | 1675 |
DDX58,LAMP1,NLRX1,RPS6KA1,HLA-E,PSME2,TAP1,CALM3,PSMD10,PSME1,ITPR2,PRKACA,HLA-A,CALM2,PSMD1,RPS6KA2,PIK3AP1,PLCG2,DUSP10,MAPK11,SCARA3,LGMN,CNPY3,SYK,RASGRP1,SMAGP,PARP9,PLSCR1,RIPK2,PSMB4,TNIP1,ITCH,USP18,CALM1,ITPR3,DUSP4,ELK1,FOS,PSMA4,SOCS3,MAPKAPK2,CTSL,HLA-B,JAK1,PVRL2,PELI2,ITPR1,NFKBIA,NMI,NOD2,NLRC5,ERAP1,IRF7,IFIH1,TMEM173 |
| 2.871e-03 | -5.85 | aldehyde dehydrogenase [NAD(P)+] activity | molecular function | GO:0004030 | 7 | 4 | 16491 | 1673 |
ALDH3B1,ALDH2,ALDH3A2,ALDH1A3 |
| 2.879e-03 | -5.85 | organelle subcompartment | cellular component | GO:0031984 | 296 | 45 | 17570 | 1756 |
PIFO,SORT1,GOLIM4,SCOC,ATP9A,ARFGEF1,RGS20,TGOLN2,RAB6A,B4GALT4,BCAP31,SLC9A7,NCS1,HLA-A,CHPF,AP1M2,FUT2,CDH1,STIM1,FUT8,FUT1,SORL1,RAB27B,GCNT1,SULF2,CPD,B3GALT6,CHSY3,ATL1,COG2,FURIN,KIF13A,SLC11A2,ARFRP1,RAB38,OPTN,GNAS,GALNT3,NUCB1,WIPI1,ATP7B,GPER1,ST3GAL1,GOLGB1,ARFGEF3 |
| 2.880e-03 | -5.85 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 90 | 18 | 17758 | 1761 |
TTC39B,PLSCR1,SH3BGRL,STAT4,ITGA6,NUCB2,ATP10D,ENDOD1,IGF1R,ITGB8,SNX18,LRIG1,AHCY,SELK,ITGAV,TIAM1,GPX4,RRAGD |
| 2.883e-03 | -5.85 | adrenal_gland-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-pheochromocytoma | 50 | 12 | 17775 | 1757 |
GNAS,CDH1,NF2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 2.883e-03 | -5.85 | thyroid-chronic_thyroiditis | COSMIC cancer mutations | thyroid-chronic_thyroiditis | 50 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 2.883e-03 | -5.85 | chronic_thyroiditis | COSMIC cancer mutations | chronic_thyroiditis | 50 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 2.883e-03 | -5.85 | negative regulation of intracellular transport | biological process | GO:0032387 | 130 | 24 | 16441 | 1675 |
TXN,ERLEC1,NFKBIE,THRA,LITAF,RAB23,PSMD10,SLC25A5,BARD1,APC2,SNX12,IER3,NOV,SP100,BMP7,CABP1,NFKBIA,UBE2J1,DAB2IP,MDFIC,YOD1,PKIA,MDFI,CHP1 |
| 2.886e-03 | -5.85 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | 126 | 23 | 17758 | 1761 |
HECA,B3GNT2,TSC22D3,TMX4,PTGER4,TTC7A,DUSP4,ZFAND5,TP53INP2,STK17B,IRS2,MGAT4A,ZFP36,FOSB,NR4A3,DUSP10,NR4A2,PDE4D,CNOT6L,TIPARP,MYLIP,TOB1,ESYT2 |
| 2.886e-03 | -5.85 | MODULE_248 | MSigDB lists | MODULE_248 | 126 | 23 | 17758 | 1761 |
ARHGEF11,CRYM,MPP1,SNTB2,STAT4,PDCL,PRKCQ,YES1,MERTK,DGKE,SOCS3,BCAR3,PLCG1,JAK1,PDLIM3,WFS1,CDH3,PITPNA,DLG3,JAK3,SHROOM2,ZBTB33,CYP1B1 |
| 2.887e-03 | -5.85 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 423 | 60 | 17758 | 1761 |
CCNE2,SPRED1,CPEB4,IQGAP1,ITGA6,TGFBR1,BCL2L1,RAB6A,POMGNT1,ETS1,PHLDA1,DNAJB9,HDAC9,RASSF8,CYP1A1,CA2,IL6ST,KLF3,DLG1,PLK4,TNFRSF12A,BUB1,CTTN,TMEM64,LMAN1,MAST4,GM2A,PPIF,DOCK4,PCGF5,TRIM8,CD55,ELK3,RGMB,SLC39A8,CYB5R2,EIF5A2,EZR,DNAJB14,LDB2,STX3,DCP2,FAS,SLCO4A1,SLC6A6,UEVLD,KBTBD2,NFKBIA,ITPR1,OTUB2,FGD6,YOD1,NFKBIZ,MLKL,HMGA1,GEM,MAFF,TOB1,ESYT2,NXT2 |
| 2.898e-03 | -5.84 | tissue migration | biological process | GO:0090130 | 81 | 17 | 16441 | 1675 |
EPB41L5,GRHL2,NR4A1,TGFBR1,LOXL2,PKN1,ANLN,EMP2,S100A2,GPLD1,NOV,PTEN,SCG2,PIK3CA,EPHB4,ARSB,CYP1B1 |
| 2.898e-03 | -5.84 | multicellular organismal catabolic process | biological process | GO:0044243 | 81 | 17 | 16441 | 1675 |
COL9A3,ADAMTS2,MRC2,COL6A2,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,COL16A1 |
| 2.901e-03 | -5.84 | microtubule cytoskeleton organization | biological process | GO:0000226 | 355 | 53 | 16441 | 1675 |
GAS2L1,SPC25,AK7,NDC80,KIF23,GPSM2,STIL,LMNA,WEE1,SS18,LRRC6,LLGL2,KIF14,TBCD,DLG1,NEK2,PLK4,TUBG1,SPRY2,CHP1,DNAAF3,PLK1,SPEF2,CAMSAP3,SUN2,CENPA,RHOA,KIF20A,CAPN6,CFAP46,FIGNL1,TACC1,ASPM,MYBL2,STMN3,EZR,NUSAP1,KIF11,BBS2,RANBP9,DAG1,CDK1,NIN,DCTN6,MAP2,PLK2,AURKA,PPP2R3C,CENPE,NDE1,RGS14,WDR62,ESPL1 |
| 2.910e-03 | -5.84 | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | 218 | 35 | 17758 | 1761 |
LGALS3,BLVRB,EPHA4,ARL4C,KCTD12,IL13RA1,ETS1,FAM46C,DENND2D,CXCL16,CALD1,PASK,SGK1,FAM102A,CTTN,MARCH2,RCAN3,CITED2,MYBL1,CDKN2D,RASGRP1,CYP1B1,SULF2,SNTB2,CYP4F3,CDK5R1,CRISPLD2,STK17A,GABARAPL1,SERPINA1,SECTM1,TMC5,TOB1,PCSK5,DOCK9 |
| 2.910e-03 | -5.84 | ATPASE_E1_E2 | prosite domains | PS00154 | 36 | 10 | 11866 | 1235 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.910e-03 | -5.84 | CSR_EARLY_UP.V1_UP | MSigDB lists | CSR_EARLY_UP.V1_UP | 156 | 27 | 17758 | 1761 |
PPIF,PHF20L1,ELK3,REPS2,RIPK2,RGMB,FRMD6,DDIT4L,PLAUR,SOX9,CD274,BCAR1,ETS1,CRISPLD2,BCAR3,PLCH1,UAP1,GATA2,PHLPP2,FJX1,YOD1,TNFRSF12A,HMGA1,ST3GAL1,SPRY2,DCBLD1,CD33 |
| 2.910e-03 | -5.84 | VERHAAK_GLIOBLASTOMA_CLASSICAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_CLASSICAL | 156 | 27 | 17758 | 1761 |
SSH3,ARAP2,ARAP3,SOX9,HMG20B,TRIB2,DAG1,TEAD3,FZD7,GNAS,SNTA1,PDGFA,IRS2,SLC4A4,ITGB8,C19orf66,ITGA7,MEGF8,OSBPL3,SIPA1L1,HS3ST3B1,EPHB4,PLIN3,CLIP2,SPRY2,RASGRP1,PCSK5 |
| 2.914e-03 | -5.84 | regulation of actin cytoskeleton organization | biological process | GO:0032956 | 267 | 42 | 16441 | 1675 |
NF2,SSH1,ADD1,EPS8,SDC4,ARFGEF1,F11R,NCKAP1,SPTB,PDGFA,CTGF,DLG1,TACSTD2,DIXDC1,CTTN,NEB,CCDC88A,SSH3,RHOA,FMN1,PIK3R1,PTGER4,RGCC,EZR,PRKCQ,EPHA1,CDK5R1,RASA1,AP1AR,SWAP70,PLEKHH2,ARHGEF19,LIMK1,CTSV,TRIOBP,TMOD2,SPTBN5,EFNA5,ARF6,ARPC2,SHROOM2,F2RL1 |
| 2.914e-03 | -5.84 | epidermis development | biological process | GO:0008544 | 267 | 42 | 16441 | 1675 |
EXPH5,CASP3,LGR4,GRHL2,ST14,SOX9,LRP4,CRABP2,TNFRSF19,TMC1,FZD6,PLS3,ELF3,ZDHHC21,CD109,PDGFA,IGF1R,CTGF,GRHL1,CDH3,ALDH3A2,HES1,KLK5,PPARA,TFAP2C,COL7A1,SCRIB,LDB2,SAV1,PITX2,GNAS,AGPAT2,FGFR2,CTSV,DBI,HDAC1,OVOL1,KLK7,HOXB13,PLOD3,GAB1,HOXC13 |
| 2.917e-03 | -5.84 | Type I pneumocyte differentiation | biological process | GO:0060509 | 7 | 4 | 16441 | 1675 |
THRB,LTA4H,THRA,NFIB |
| 2.917e-03 | -5.84 | lacrimal gland development | biological process | GO:0032808 | 7 | 4 | 16441 | 1675 |
FGFR2,RARG,SOX9,IGSF3 |
| 2.917e-03 | -5.84 | male mating behavior | biological process | GO:0060179 | 7 | 4 | 16441 | 1675 |
GRN,PTEN,HEXB,GRIN1 |
| 2.917e-03 | -5.84 | centrosome separation | biological process | GO:0051299 | 7 | 4 | 16441 | 1675 |
AURKA,NDE1,KIF11,NEK2 |
| 2.922e-03 | -5.84 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP | 179 | 30 | 17758 | 1761 |
BIN1,THRB,LZTFL1,NR3C1,HLA-F,ATP2C2,PIK3R1,CXorf57,MTRF1L,TDRKH,CYB561,TCF7,IL18,LRRC1,EPHA1,FOXL1,ZFYVE9,ABCD4,SCML1,MARCH8,ZNF432,TRANK1,TSPAN6,KBTBD2,RPL39,FAM13B,MDFIC,HLA-C,ECE1,MAP3K5 |
| 2.922e-03 | -5.84 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | 179 | 30 | 17758 | 1761 |
PLA2G4A,TXN,UGP2,IL15RA,IL15,IFITM3,HAPLN3,PSME2,STAT4,NUB1,PPFIBP2,AK4,SAMD9,CD274,BLVRA,MORF4L2,DUSP4,HERC6,FNDC3A,STEAP1,PDGFA,SWAP70,SERPINA1,ITGB8,CD70,SELK,LRIF1,ZNF701,LAMP3,PARP9 |
| 2.929e-03 | -5.83 | Sad1_UNC | pfam domains | PF07738 | 7 | 4 | 16629 | 1696 |
SUN1,SUN2,SUN3,SUCO |
| 2.930e-03 | -5.83 | REACTOME_APOPTOSIS | MSigDB lists | REACTOME_APOPTOSIS | 141 | 25 | 17758 | 1761 |
CASP3,BMF,PSMB4,ADD1,AKT1,PSME2,CASP9,TP53,PSMD10,PRKCQ,PSME1,BCL2L1,PSMA4,BCAP31,LMNA,FAS,DAPK2,PSMD1,CDH1,DNM1L,H1F0,DAPK1,BAX,UNC5B,OCLN |
| 2.936e-03 | -5.83 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP | 258 | 40 | 17758 | 1761 |
UNKL,LGR4,IL15,CENPI,RASSF7,CTDSPL,C5orf30,PBX3,COL4A5,B4GALT4,SEPP1,HOXB2,TNS3,PHF7,FRY,METTL7A,IQCE,GOT1,WWP1,OSTF1,SNX10,NCOA2,CTH,WBP5,METAP2,ACO1,EPHA1,RAB38,CDK5R1,RHEB,SOX13,MAN2A2,IDE,NGFRAP1,DCK,HOXA9,AGBL5,MAP3K5,TMEM14A,DOCK9 |
| 2.939e-03 | -5.83 | regulation of protein import into nucleus | biological process | GO:0042306 | 167 | 29 | 16441 | 1675 |
DDX58,SIRT1,TXN,RHOA,NFKBIE,THRA,PIK3R1,LITAF,RAB23,PSMD10,TGFBR1,IL18,PRKCQ,APC2,IL18R1,FZD7,NOV,CDH1,DACT1,BMP7,CABP1,NFKBIA,DAB2IP,MDFIC,WNT3A,TMEM173,PKIA,MDFI,CHP1 |
| 2.940e-03 | -5.83 | NABA_ECM_REGULATORS | MSigDB lists | NABA_ECM_REGULATORS | 234 | 37 | 17758 | 1761 |
SERPINE2,ST14,P3H2,CTSZ,ADAMTSL4,CD109,CTSC,CST3,FAM20B,ADAM15,EGLN3,SULF2,ADAMTS2,TIMP2,F12,LOXL2,CTSL,MMP15,TIMP3,SERPINA1,HPSE,PLOD2,P4HA2,MMP17,P4HA3,CTSV,BMP1,ADAMTS14,CTSA,SERPINI1,SERPINB6,PLOD3,SERPINB1,EGLN1,TLL2,PCSK5,ADAMTS16 |
| 2.943e-03 | -5.83 | DAIRKEE_TERT_TARGETS_UP | MSigDB lists | DAIRKEE_TERT_TARGETS_UP | 348 | 51 | 17758 | 1761 |
EPAS1,THRA,LRP4,PTTG1,ABCG2,PDIA3,HMGN3,ISOC2,HDAC6,GSTP1,EMP2,AIP,LGALS3BP,IRF2BPL,APOBEC3B,CDKN2C,ADRBK1,PAIP2B,CDK16,SIVA1,ATP5H,BAX,ECI2,MAPK11,ALDH7A1,SEMA3G,CNPY3,ALDH3A2,CKS2,PPIF,PMPCB,DRAP1,PTGER4,HMG20B,COL7A1,ZNF618,DCP2,DDOST,COL13A1,DBI,SLC4A3,PGRMC1,FAM83D,MLKL,PLOD3,PPP2R2D,ARHGEF9,DEF6,CAPN1,CD33,ARHGEF4 |
| 2.945e-03 | -5.83 | V$NFKAPPAB_01 | MSigDB lists | V$NFKAPPAB_01 | 242 | 38 | 17758 | 1761 |
BMF,SDC4,TP53,IL27RA,TRIB2,DDR1,SPTB,BMP2K,CXCL16,CTGF,SLC44A1,ANKFN1,KCNS3,CD70,SLC12A2,RIMS2,XKR8,CPD,SUN2,TNIP1,FOXJ2,SLC11A2,ATP1B1,CD40,PRX,CYB5A,CD83,BFSP1,RAP2C,NOD2,UACA,FAM117A,GRIN2D,SP6,ARPC2,JAK3,COL16A1,JARID2 |
| 2.960e-03 | -5.82 | CCNB1 (cyclin B1) | protein interactions | 891 | 90 | 19 | 16036 | 1726 |
GAS2L1,PLK1,SIRT1,RUNX2,FOXM1,RALBP1,PBK,CDC20,NDC80,HERC5,PKMYT1,CCNF,CCNB1,CDK1,ITPR1,CDKN1B,CCNB2,ESPL1,CKS2 |
| 2.961e-03 | -5.82 | ELECTRON_TRANSPORT_GO_0006118 | MSigDB lists | ELECTRON_TRANSPORT_GO_0006118 | 50 | 12 | 17758 | 1761 |
DUOX1,ALDH5A1,CYP4F11,DHRS2,CYB5R2,SLC25A13,PDIA5,BLVRA,SPR,POR,GPX4,CYP1B1 |
| 2.964e-03 | -5.82 | regulation of cellular component size | biological process | GO:0032535 | 315 | 48 | 16441 | 1675 |
SEMA6B,SSH1,ADD1,RET,EPS8,ARFGEF1,PLXNA1,CRABP2,SPTB,PTEN,DPYSL2,MEGF8,KCNN4,DLG1,TNFRSF12A,CTTN,SEMA3G,IQGAP3,WNT3A,SLC12A2,NEB,SEMA3B,SSH3,CLCN3,RAB3B,RHOA,AKT1,FMN1,ANO6,EZR,RASA1,CDK5R1,PLEKHH2,SWAP70,SEMA4D,LIMK1,TRIOBP,NRG1,SPTBN5,EFNA5,TMOD2,ARF6,ARPC2,SHROOM2,F2RL1,SEMA3A,L1CAM,RARG |
| 2.977e-03 | -5.82 | negative regulation of substrate adhesion-dependent cell spreading | biological process | GO:1900025 | 11 | 5 | 16441 | 1675 |
AP1AR,TACSTD2,MFI2,FBLN1,CORO1C |
| 2.981e-03 | -5.82 | multicellular organismal macromolecule metabolic process | biological process | GO:0044259 | 88 | 18 | 16441 | 1675 |
COL9A3,ADAMTS2,MRC2,COL6A2,P3H2,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,COL16A1 |
| 2.982e-03 | -5.82 | regulation of cellular protein localization | biological process | GO:1903827 | 504 | 71 | 16441 | 1675 |
LZTFL1,SORBS1,TXN,NF2,THRA,TP53,ERBB2,IL18,BCL2L1,CCNB1,PRKACA,BARD1,APC2,BCAP31,ARHGEF16,NOV,CDH1,SP100,DACT1,CABP1,DLG1,DAB2IP,CHP1,SIRT1,ERLEC1,TRIM8,AKT1,NBPF3,EZR,PRKCQ,CDK1,FZD7,PPP2R5A,NRG1,ARF6,DDX58,TCAF1,BMF,PINK1,NFKBIE,RAB23,PSMD10,TGFBR1,IL18R1,LMNA,KIF5B,ITGA3,BMP7,FAM20B,UBE2J1,NEK2,SORL1,MDFIC,WNT3A,MDFI,HES1,RHOA,PIK3R1,LITAF,TP53INP2,STX3,CDK5R1,NUCB1,TMEM30A,CDCA5,NFKBIA,YOD1,GPER1,FZD5,PKIA,TMEM173 |
| 2.983e-03 | -5.81 | ITGA6 (integrin alpha 6) | protein interactions | 3655 | 35 | 10 | 16036 | 1726 |
BIN1,CD63,HLA-E,CD82,CALM1,PDIA3,HLA-C,B4GALT4,LGALS3BP,PCSK5 |
| 2.983e-03 | -5.81 | TBXA2R (thromboxane A2 receptor) | protein interactions | 6915 | 35 | 10 | 16036 | 1726 |
GNAS,RHOA,SIVA1,PRKG1,GRK6,PKN1,PLCB2,PRKACA,GNA11,PRDX4 |
| 2.987e-03 | -5.81 | GSE17580_TREG_VS_TEFF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_UP | 187 | 31 | 17758 | 1761 |
TTC39B,UPF3B,CDKN1C,PQLC3,CORO2A,SH3BGRL,CBX6,PHLPP1,DHRS3,PCTP,SESN1,SYTL2,GPLD1,SOCS3,GABARAPL1,RCN1,EPCAM,GNB5,TWSG1,H1F0,SYT7,MATN2,CD70,SH3BGRL2,PIM1,F2R,CPPED1,FAH,ABCC1,XDH,RRAGD |
| 2.987e-03 | -5.81 | MODULE_244 | MSigDB lists | MODULE_244 | 187 | 31 | 17758 | 1761 |
PLK1,SMARCA2,PEX6,EPHA4,AK4,KIF23,RUNX3,PRKCQ,PDK3,PKN1,MERTK,KIF11,CDK1,PRIM1,TOP2A,WEE1,IGF1R,CDK16,DCK,PTK7,LIMK1,KIF14,STK38,PLK4,NEK2,GTF2F2,BUB1,CENPE,MELK,ABCC1,SEPHS1 |
| 2.987e-03 | -5.81 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | 187 | 31 | 17758 | 1761 |
NKX3-1,UGT8,HEBP1,XYLT1,PBX3,CR2,DDR1,SESN1,GALNT3,IRS2,DIRAS3,APLP2,RAB15,NEIL1,FAM46A,PAIP2B,PRCP,MMP17,MITF,AOX1,TPST1,DTX4,SORL1,TSPAN13,KLF9,ANXA9,SYT13,NR3C2,TPCN1,SCN3A,GCNT1 |
| 2.987e-03 | -5.81 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | 187 | 31 | 17758 | 1761 |
HECA,MRC2,CAST,RAPGEF2,INPP5D,CBX6,HTATIP2,YES1,H2AFV,STIL,PSMA4,ARHGEF26,LMNA,RAD23A,SGPL1,GNS,DCTN6,TTC21B,DAZAP1,MID1IP1,PTK7,MATN2,S100A5,TMEM51,CCDC69,CLMN,KLF11,MANF,MAST4,HOXC13,XKR8 |
| 2.987e-03 | -5.81 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | 187 | 31 | 17758 | 1761 |
ARHGEF3,ZNF395,PCBP3,TSC22D3,ESRP1,EPHA4,TMX4,CYB561,FOS,FAM46C,CYP26A1,RASGRP2,IRS2,MARCH8,SCARB2,ADD3,TIMP3,MADD,RYK,SORL1,SGK1,NR4A2,CRY2,SEMA3G,TBC1D4,MYBL1,NR3C2,TOB1,RASGRP1,SMAGP,KLF7 |
| 2.987e-03 | -5.81 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | 187 | 31 | 17758 | 1761 |
ZMAT1,PCOLCE,ARHGEF3,MBP,TTC39B,BTNL9,OSTM1,CPT2,STAT4,ITCH,CNOT8,ARMC7,SEPP1,IL18R1,FUCA1,MDM1,BANK1,ZFP36,STK38,SIPA1L1,AKR1B1,ERAP1,CNOT6L,ARF6,TMEM120A,PLCB2,NRBP1,OSGIN1,ATP2B1,GM2A,ARHGEF4 |
| 2.987e-03 | -5.81 | VEGF_A_UP.V1_DN | MSigDB lists | VEGF_A_UP.V1_DN | 187 | 31 | 17758 | 1761 |
HMMR,RAB3B,CENPA,DLGAP5,UGP2,AASS,RASA2,SAT1,NDC80,C5orf30,KIF23,SLC7A2,YES1,ATP8B3,CCNB1,SPTLC2,KIF11,STEAP1,NCOA3,UAP1,RND3,PLK4,OSTF1,BUB1,RP2,KLF9,CENPE,PTPRE,CCNB2,MYO5A,CKS2 |
| 2.987e-03 | -5.81 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 187 | 31 | 17758 | 1761 |
EPB41L5,REC8,WASF3,GCA,PDGFC,NKX3-1,UGP2,IGFBP6,OSTM1,TMX4,DSE,NFIB,PSIP1,SIRPA,FZD7,DPYSL3,IRF2BPL,ANKRD10,TIMP3,RAB11FIP2,CALD1,FRAS1,FAM13B,REEP1,CLIP4,SLC39A10,TIAM1,TOB1,RNF146,ATP2B1,SOCS5 |
| 2.987e-03 | -5.81 | GSE3982_NEUTROPHIL_VS_TH1_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_UP | 187 | 31 | 17758 | 1761 |
DOCK4,CCNI,TRIM8,SORBS1,DNAJC3,ARMC7,CUL4B,ERBB2,TFAP2C,BTN3A1,ARHGDIB,LOXL2,DPP8,PARM1,SCML1,APLP2,ATP6V0B,ACAP2,FAM46A,CTGF,TRANK1,SIPA1L1,SECTM1,FAM63A,RYK,ZDHHC7,LTBP2,L1CAM,ALS2CL,CTDSP2,ARHGEF4 |
| 2.987e-03 | -5.81 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | 187 | 31 | 17758 | 1761 |
CASP3,FADS2,DDB2,SEC61B,HJURP,STAU2,CDC20,SDC4,HEXB,TAP1,GLO1,CCNF,IDH1,BARD1,FANCI,FRMD4B,GALNT3,APOBEC3B,TOP2A,WEE1,PSMD1,RBL1,GDE1,KCNK1,NAT1,PHTF1,ITPR1,PPP2R3C,MINPP1,CCNB2,ESPL1 |
| 2.991e-03 | -5.81 | LEIN_NEURON_MARKERS | MSigDB lists | LEIN_NEURON_MARKERS | 63 | 14 | 17758 | 1761 |
SMARCA2,KIFC2,TRANK1,REPS2,MADD,RAB6A,PACSIN1,LRP11,NDFIP1,PRKACA,ALCAM,BEX2,MYO5A,GABARAPL1 |
| 2.992e-03 | -5.81 | SAM_PNT | pfam domains | PF02198 | 11 | 5 | 16629 | 1696 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 2.992e-03 | -5.81 | 2OG-FeII_Oxy_3 | pfam domains | PF13640 | 11 | 5 | 16629 | 1696 |
EGLN3,P4HA2,P3H2,P4HA3,EGLN1 |
| 2.993e-03 | -5.81 | PROTEIN_HOMODIMERIZATION_ACTIVITY | MSigDB lists | PROTEIN_HOMODIMERIZATION_ACTIVITY | 119 | 22 | 17758 | 1761 |
S100A11,HEXB,ABCG2,CDA,CR2,EIF2AK1,BARD1,SLC9A7,FOXP2,TOP2A,CARD8,PVRL2,CST3,MAP3K9,BAX,ANXA9,GLA,MAP3K5,NRBP1,CCDC88A,S100A6,ABCG1 |
| 2.994e-03 | -5.81 | REGULATION_OF_PROGRAMMED_CELL_DEATH | MSigDB lists | REGULATION_OF_PROGRAMMED_CELL_DEATH | 340 | 50 | 17758 | 1761 |
CASP3,DAP,TP53,BCL2L1,AIFM2,GSTP1,BARD1,ADAMTSL4,IER3,TOP2A,CDKN2C,DAPK2,CARD8,ADORA1,IGF1R,PTEN,SIVA1,DAPK1,BAX,BCL6,CDKN1B,CD70,PIM1,F2R,CDKN2D,MX1,ACVR1C,GCLC,CASP9,HTATIP2,RUNX3,GLO1,BCAR1,STK17B,CDK1,CASP4,CDK5R1,RASA1,SOCS3,STK17A,FAS,SEMA4D,SCG2,MADD,HDAC1,MAP3K5,AIFM3,HSPB1,IFI6,HIPK3 |
| 3.016e-03 | -5.80 | ovary-low_malignant_potential_(borderline)_tumour-serous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-serous | 32 | 9 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 3.017e-03 | -5.80 | peptidase activator activity | molecular function | GO:0016504 | 37 | 10 | 16491 | 1673 |
CARD8,PINK1,NKX3-1,PCOLCE,CTSC,NGFRAP1,PSME2,CDKN1B,PSME1,FBLN1 |
| 3.022e-03 | -5.80 | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | 299 | 45 | 17758 | 1761 |
CCNE2,CASP3,NFKBIE,IGFBP6,CDKN1C,HLA-E,HLA-F,TMX4,TP53,PDCL,ERBB2,OSR2,SPR,GSTP1,TNFSF9,HLA-A,SAC3D1,CDKN2C,CDK16,TMBIM6,TRIM21,IFIT1,NPTXR,S100A13,CTH,CYP1B1,PPIF,SHMT1,NR4A1,MICB,SAT1,NFE2L1,MYBL2,RNF113A,PKMYT1,TP53I3,GABARAPL1,MDK,PGF,PITX2,SLC25A4,AGPAT2,GPRC5B,NAT1,TOB1 |
| 3.025e-03 | -5.80 | negative regulation of NF-kappaB transcription factor activity | biological process | GO:0032088 | 68 | 15 | 16441 | 1675 |
SIRT1,DAP,BMP7,ITCH,SIVA1,NFKBIA,NLRC5,NOD2,ARRB1,PSMD10,TRIM21,DAB2IP,ERBB2IP,CYP1B1,CHP1 |
| 3.027e-03 | -5.80 | proteoglycan metabolic process | biological process | GO:0006029 | 95 | 19 | 16441 | 1675 |
CHSY3,B3GALT6,HSPG2,XYLT1,HEXB,SDC4,DSE,SDC1,FOXL1,CHPF,GLCE,HS6ST1,HPSE,IMPAD1,XYLT2,HS3ST3B1,ARSB,NDST3,SULF2 |
| 3.037e-03 | -5.80 | stem cell differentiation | biological process | GO:0048863 | 190 | 32 | 16441 | 1675 |
SEMA6B,RUNX2,RET,SOX9,TGFBR1,FAM101B,FGF19,EFNB1,EPCAM,BMP7,ADAM15,TWIST1,C10orf54,SEMA3G,ETV4,SEMA3B,EPB41L5,HES1,S100A4,AMER1,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,FAM83D,NRG1,SOX8,OSR1,SEMA3A,JARID2 |
| 3.041e-03 | -5.80 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | 195 | 32 | 17758 | 1761 |
PINK1,POC1B,DNAJB2,SDC4,PKN1,FAM167A,PSIP1,TMEM63A,ADRBK1,FXYD5,C10orf54,TGIF1,ATL1,SUN2,PLEKHA6,MBP,ADCK3,SNTB2,ARHGDIB,SAV1,ARHGAP24,PLCG1,PHLPP2,WFS1,SLC4A3,DTX4,PRDM5,HS3ST3B1,ARF6,WBSCR27,TBC1D4,KLF7 |
| 3.041e-03 | -5.80 | GSE20715_0H_VS_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_UP | 195 | 32 | 17758 | 1761 |
SORT1,ZNF395,FAM198B,EPS8L2,WWP2,CDKN2C,DAPK2,RPS6KA2,DACT1,ELF5,SLC44A2,POF1B,SORL1,TACSTD2,LIMCH1,RFX5,MYLIP,PTPRE,HPS3,ARAP2,IFITM3,CR2,ARHGDIB,SESN1,CMTM7,SLC6A6,H1F0,NMI,FHL1,GLCCI1,SERPINB1,GAB1 |
| 3.041e-03 | -5.80 | WIERENGA_STAT5A_TARGETS_DN | MSigDB lists | WIERENGA_STAT5A_TARGETS_DN | 195 | 32 | 17758 | 1761 |
BIN1,WASF3,ARHGEF3,ARAP3,LMTK3,DEPDC1,UBASH3B,CTDSPL,PDIA5,VASH1,ETS1,TMEM63A,CCND1,XYLT2,PLCG2,CD9,MTMR11,FAR2,PLCB2,SLC12A2,PPIF,SUSD3,TRIM8,SLC37A1,C3orf52,MYEOV,LHFPL2,NFIB,SPNS3,IRS2,BANK1,SH3BGRL2 |
| 3.041e-03 | -5.80 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | 195 | 32 | 17758 | 1761 |
NFKBIE,TSC22D3,FAM134A,PDIA3,TESK2,PKN1,PDIA4,AKIRIN1,TYMP,PTEN,DPYSL2,DUSP10,AHCY,OSTF1,KLF9,CKAP4,PIK3R1,RNF19B,STK17B,UAP1,HNRNPH2,RAP2C,NFKBIA,KLF11,NR4A2,ATP1B3,SPCS3,PLIN3,REEP4,TOB1,MAFF,RRAGD |
| 3.041e-03 | -5.80 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 195 | 32 | 17758 | 1761 |
TXN,TRIP10,AASS,DNAJC3,TESK2,NRP2,IER3,TYMP,CDH1,PAIP2B,RRBP1,ANKRD12,TRIM21,PIM1,PDE4D,PLSCR1,TNIP1,PLAUR,RAPGEF2,LITAF,AK4,RNF19B,LHFPL2,CYB5A,CD83,PLCH1,SERPINA1,RND3,FGFR2,WIPI1,DTX4,GEM |
| 3.043e-03 | -5.79 | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | 21 | 7 | 17775 | 1757 |
AKT1,IDH1,FGFR2,PTEN,RET,PIK3R1,PIK3CA |
| 3.043e-03 | -5.79 | endometrioid | COSMIC cancer mutations | endometrioid | 21 | 7 | 17775 | 1757 |
AKT1,IDH1,FGFR2,PTEN,RET,PIK3R1,PIK3CA |
| 3.043e-03 | -5.79 | haemangioma | COSMIC cancer mutations | haemangioma | 21 | 7 | 17775 | 1757 |
GNAS,PLCG1,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 3.067e-03 | -5.79 | MODULE_119 | MSigDB lists | MODULE_119 | 134 | 24 | 17758 | 1761 |
MX1,ARAP2,IL15,STAT4,SYNE2,PTTG1,SELL,CR2,PRKCQ,TRIB2,BBS2,HLA-A,NOV,BANK1,KLF12,SPINT2,PASK,ABCB1,NLRC5,PIK3C2B,IRF7,ARMCX6,APOBEC3G,RRAGD |
| 3.084e-03 | -5.78 | BIOCARTA_PDGF_PATHWAY | MSigDB lists | BIOCARTA_PDGF_PATHWAY | 32 | 9 | 17758 | 1761 |
PDGFA,PLCG1,JAK1,STAT4,PIK3R1,PIK3CA,ELK1,FOS,RASA1 |
| 3.084e-03 | -5.78 | GRADE_COLON_CANCER_DN | MSigDB lists | GRADE_COLON_CANCER_DN | 32 | 9 | 17758 | 1761 |
RMND5A,CNTNAP1,SLC4A4,METTL7A,PLOD2,SGK1,ELK1,SEPP1,TP53INP2 |
| 3.084e-03 | -5.78 | PID_NETRIN_PATHWAY | MSigDB lists | PID_NETRIN_PATHWAY | 32 | 9 | 17758 | 1761 |
PLCG1,RHOA,PIK3R1,DAPK1,PIK3CA,PITPNA,YES1,UNC5B,BCAR1 |
| 3.084e-03 | -5.78 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 203 | 33 | 17758 | 1761 |
LZTFL1,UBASH3B,RASA2,VARS2,PM20D2,SYTL2,TOP2A,FUT8,TOX2,DAPK1,TSPAN13,TAGLN2,PDE4D,BTBD3,SPRY2,CKS2,ACBD5,PCGF5,TIMP2,B3GNT2,PLSCR1,OXR1,PTGER4,VEZT,STK17B,SOCS3,ANKRD10,CACHD1,CDCA7L,NFKBIZ,NR4A2,CMPK2,TOB1 |
| 3.086e-03 | -5.78 | mucinous | COSMIC cancer mutations | mucinous | 38 | 10 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 3.087e-03 | -5.78 | ZnF_C4 | smart domains | SM00399 | 46 | 12 | 9131 | 997 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 3.091e-03 | -5.78 | regulation of establishment of protein localization to plasma membrane | biological process | GO:0090003 | 49 | 12 | 16441 | 1675 |
KIF5B,SORBS1,ITGA3,PPP2R5A,AKT1,PIK3R1,DLG1,EZR,BCL2L1,GPER1,ARF6,ARHGEF16 |
| 3.096e-03 | -5.78 | response to nitrogen compound | biological process | GO:1901698 | 987 | 127 | 16441 | 1675 |
CASP3,SPRED1,SORBS1,SLC2A4,SSH1,FOXM1,PSME2,NRG2,ERBB2,PSME1,ITPR2,BCL2L1,PRKACA,PDGFB,SDC1,SPTB,CALM2,CCND1,PDGFA,ATP6V0B,SESN3,PSMD1,CDH1,CTGF,SHC3,DPYSL2,KLF3,FOSB,SRR,PIK3CA,AKR1B1,CDKN1B,DAB2IP,GOT1,PDE4D,IFIT1,RASGEF1A,RASGRP1,FRS3,SIRT1,RIPK2,AKT1,ACVR1C,EZR,AGO4,PRKAR2B,PRKCQ,ERBB2IP,PRKRA,POR,CASP4,DAG1,RHEB,SOCS3,IRS2,ENPP1,DUOX1,IDE,JAK1,NOD2,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,GAB1,RRAGD,DDX58,PRKAA2,SORT1,CPEB4,RASA2,DGKQ,SOX9,CALM3,GABRG2,PSMD10,SELL,FGF19,HDAC9,IGF1R,PTEN,BMP7,COL6A1,BAX,TMBIM6,ERBB3,NCAM1,MYO5A,GCNT1,PDGFC,RASGRF1,RHOA,SHMT1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,FOS,BCAR1,PSMA4,RASA1,GPLD1,GNAS,TIMP3,PRKAG2,FGFR2,NFKBIA,SH3BP4,NR4A3,GRIN2D,NR4A2,GPER1,MAP3K5,JAK3,TBC1D4,CPEB2,COL16A1,TMEM173,EGLN1 |
| 3.100e-03 | -5.78 | MODULE_253 | MSigDB lists | MODULE_253 | 21 | 7 | 17758 | 1761 |
KIF23,CENPE,ARSB,MAP2,KIF11,SNTB2,KIF14 |
| 3.100e-03 | -5.78 | SAGIV_CD24_TARGETS_UP | MSigDB lists | SAGIV_CD24_TARGETS_UP | 21 | 7 | 17758 | 1761 |
TRIM8,SLC4A4,ASPM,CABP1,FRYL,N4BP3,ARFGEF1 |
| 3.100e-03 | -5.78 | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | 21 | 7 | 17758 | 1761 |
AURKA,TUBG1,DUSP4,SERPINE2,FOXM1,ASPM,CKS2 |
| 3.100e-03 | -5.78 | VERNELL_RETINOBLASTOMA_PATHWAY_DN | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_DN | 21 | 7 | 17758 | 1761 |
CLIP4,CCND1,DYNLRB1,CTGF,CITED2,ITGB8,SH3BP4 |
| 3.100e-03 | -5.78 | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | 21 | 7 | 17758 | 1761 |
TOP2A,KIF20A,BARD1,ASPM,CDK1,SLC2A6,NEK2 |
| 3.100e-03 | -5.78 | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION | 21 | 7 | 17758 | 1761 |
GNS,HS3ST3B1,HPSE,ARSB,GUSB,GALNS,HEXB |
| 3.100e-03 | -5.78 | ROY_WOUND_BLOOD_VESSEL_DN | MSigDB lists | ROY_WOUND_BLOOD_VESSEL_DN | 21 | 7 | 17758 | 1761 |
ATP8B1,FBXO9,KLF5,EPB41L4B,ERBB3,ATP1B1,SOX9 |
| 3.100e-03 | -5.78 | Oxoglu/Fe-dep_dioxygenase | interpro domains | IPR005123 | 21 | 7 | 18293 | 1814 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 3.100e-03 | -5.78 | Tetraspanin_CS | interpro domains | IPR018503 | 21 | 7 | 18293 | 1814 |
TSPAN1,CD63,TSPAN6,TSPAN7,CD82,TSPAN18,CD9 |
| 3.103e-03 | -5.78 | OHGUCHI_LIVER_HNF4A_TARGETS_UP | MSigDB lists | OHGUCHI_LIVER_HNF4A_TARGETS_UP | 44 | 11 | 17758 | 1761 |
SLC2A4,SLC25A4,USP18,ABCB1,DRAM1,SLC27A1,PER3,EMP2,DDR1,LEPR,CYP39A1 |
| 3.103e-03 | -5.78 | PID_ERBB2_ERBB3_PATHWAY | MSigDB lists | PID_ERBB2_ERBB3_PATHWAY | 44 | 11 | 17758 | 1761 |
NF2,AKT1,PIK3R1,PIK3CA,ERBB2,NRG2,NRG1,ERBB3,PIK3CD,FOS,PRKACA |
| 3.103e-03 | -5.78 | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | MSigDB lists | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | 44 | 11 | 17758 | 1761 |
ING1,CTGF,HPSE,CDKN1C,DHRS2,CGREF1,ABCB1,GDF15,SERPINI1,NOTCH3,ULBP2 |
| 3.103e-03 | -5.78 | ZHAN_MULTIPLE_MYELOMA_MF_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_UP | 44 | 11 | 17758 | 1761 |
CD109,DOCK4,TYMP,SHMT1,MCTP1,CDH1,NUAK1,ABHD12,DPYSL2,TMEM37,ATP13A2 |
| 3.103e-03 | -5.78 | TSENG_ADIPOGENIC_POTENTIAL_DN | MSigDB lists | TSENG_ADIPOGENIC_POTENTIAL_DN | 44 | 11 | 17758 | 1761 |
CDKN2C,B3GALNT1,ENPP1,POPDC3,CAPN6,TSPAN6,IL6ST,COL6A1,CST3,PHKA2,SESN1 |
| 3.106e-03 | -5.77 | regulation of cell morphogenesis | biological process | GO:0022604 | 530 | 74 | 16441 | 1675 |
SSH1,EPHA4,HEXB,RET,PLXNA1,MNS1,SH3KBP1,DPYSL2,DLG1,DAB2IP,TWIST1,TACSTD2,MYH14,SEMA3G,CTTN,TIAM1,S100A13,SEMA3B,SSH3,STRIP2,EZR,DAG1,ARHGAP35,SHROOM3,BHLHB9,CORO1C,LIMK1,SIPA1L1,TRIOBP,EFNA5,NRG1,ITPKA,MYL12B,LZTS1,FGD1,WASF3,SEMA6B,FBLIM1,ARAP3,BVES,TBC1D1,CIT,LRP4,EPS8,TGFBR1,CRABP2,FAM21C,FBLN1,PTEN,MEGF8,VASN,KIF13B,TNFRSF12A,WNT3A,ZRANB1,TRIM62,RIMS2,EPB41L5,RHOA,MFI2,RAPGEF2,GRIN1,RGCC,RASA1,CDK5R1,AP1AR,SEMA4D,CSNK1G1,ITGA7,FGD6,ARPC2,SEMA3A,L1CAM,ADAMTS16 |
| 3.140e-03 | -5.76 | RAMALHO_STEMNESS_DN | MSigDB lists | RAMALHO_STEMNESS_DN | 70 | 15 | 17758 | 1761 |
BIN1,PPP2R5A,PAPSS2,ACVRL1,CST3,BMP1,PACSIN1,NCAM1,RGS14,FAM101B,ABR,SIRPA,MESDC2,B4GALNT1,NIN |
| 3.140e-03 | -5.76 | GNF2_TAL1 | MSigDB lists | GNF2_TAL1 | 70 | 15 | 17758 | 1761 |
MARCH8,FECH,GCLM,CA2,ERMAP,H1F0,HEBP1,MPP1,BLVRB,EIF2AK1,MINPP1,SPTB,BMP2K,TRAK2,RAD23A |
| 3.141e-03 | -5.76 | MODULE_47 | MSigDB lists | MODULE_47 | 219 | 35 | 17758 | 1761 |
MYL9,CD99,LTBP1,MRC2,PCOLCE,LMCD1,COL18A1,SEPP1,FBLN1,CTGF,CALD1,ALDH1A3,COL6A1,NOTCH3,EGLN3,F2R,CKAP4,CYP1B1,SGCE,COL6A2,MMD,PLAUR,LOXL2,LDB2,COL12A1,FZD7,CRISPLD2,DPYSL3,EDNRA,TIMP3,SCG2,BMP1,SH3BP4,LTBP2,COL16A1 |
| 3.143e-03 | -5.76 | Regulation of actin cytoskeleton | KEGG pathways | hsa04810 | 214 | 37 | 6908 | 758 |
MYL9,SSH1,IQGAP1,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,PDGFA,ITGA3,ITGB8,PIK3CA,MYH14,PIK3CD,IQGAP3,PIKFYVE,F2R,TIAM1,SSH3,PDGFC,RHOA,PIK3R1,PIP4K2C,DIAPH2,EZR,BCAR1,MYL12A,ARHGAP35,FGFR2,LIMK1,ITGA7,ITGAV,ARPC2,MYL12B,ARHGEF4,FGD1 |
| 3.143e-03 | -5.76 | Regulation of actin cytoskeleton | KEGG pathways | ko04810 | 214 | 37 | 6908 | 758 |
MYL9,SSH1,IQGAP1,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,PDGFA,ITGA3,ITGB8,PIK3CA,MYH14,PIK3CD,IQGAP3,PIKFYVE,F2R,TIAM1,SSH3,PDGFC,RHOA,PIK3R1,PIP4K2C,DIAPH2,EZR,BCAR1,MYL12A,ARHGAP35,FGFR2,LIMK1,ITGA7,ITGAV,ARPC2,MYL12B,ARHGEF4,FGD1 |
| 3.143e-03 | -5.76 | Ald_DH_CS_CYS | interpro domains | IPR016160 | 16 | 6 | 18293 | 1814 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 3.143e-03 | -5.76 | Ald_DH_CS_GLU | interpro domains | IPR029510 | 16 | 6 | 18293 | 1814 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH3A2,ALDH1A3 |
| 3.143e-03 | -5.76 | SULFURIC_ESTER_HYDROLASE_ACTIVITY | MSigDB lists | SULFURIC_ESTER_HYDROLASE_ACTIVITY | 16 | 6 | 17758 | 1761 |
GNS,ARSB,ARSG,ARSK,GALNS,SULF2 |
| 3.143e-03 | -5.76 | MITOTIC_SISTER_CHROMATID_SEGREGATION | MSigDB lists | MITOTIC_SISTER_CHROMATID_SEGREGATION | 16 | 6 | 17758 | 1761 |
NUSAP1,CENPE,ZWINT,ESPL1,CDCA5,NDC80 |
| 3.143e-03 | -5.76 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL | 16 | 6 | 17758 | 1761 |
APLP2,GTF3A,S100A11,S100A6,PTTG1,RASGRP2 |
| 3.143e-03 | -5.76 | PID_INTEGRIN5_PATHWAY | MSigDB lists | PID_INTEGRIN5_PATHWAY | 16 | 6 | 17758 | 1761 |
TGFBR1,ITGAV,ITGB8,CYR61,SDC1,PLAUR |
| 3.157e-03 | -5.76 | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 227 | 36 | 17758 | 1761 |
GAA,CCDC109B,ALDH6A1,AASS,IQGAP1,LRP4,PDIA5,MPP5,SPR,CMTM6,ZFYVE9,SP100,RGS3,ADCK2,CRY2,TAGLN2,MCTP1,SEC61B,ZNF84,PLSCR1,SAT1,PCTP,SPTLC2,MYL12A,SP4,OPTN,ARHGAP24,ENDOD1,CDK19,HOXA9,ANXA9,RGS14,ZMIZ1,ARPC2,MYL12B,PCSK5 |
| 3.160e-03 | -5.76 | BIOCARTA_FCER1_PATHWAY | MSigDB lists | BIOCARTA_FCER1_PATHWAY | 38 | 10 | 17758 | 1761 |
PLA2G4A,CALM2,PLCG1,CALM1,PIK3R1,PIK3CA,CALM3,ELK1,FOS,SYK |
| 3.166e-03 | -5.76 | V$CREBP1_Q2 | MSigDB lists | V$CREBP1_Q2 | 243 | 38 | 17758 | 1761 |
BIN1,LTBP1,TM2D2,THRA,RET,RAB6A,TIPRL,TSPAN7,FAM167A,CHPF,AKIRIN1,IRF2BPL,DACT1,LMO4,FLRT3,FOSB,PDE4D,ARL4D,RBMS2,WBP5,PTPRU,DEPDC4,FOS,TP53INP2,ATP10D,ABR,GNAS,PITX2,PDLIM3,KCNK1,SCG2,ZNF367,NR4A3,NR4A2,GEM,OSR1,MAFF,RUSC1 |
| 3.169e-03 | -5.75 | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 105 | 20 | 17758 | 1761 |
GLIS3,PLA2G4A,CD55,CPEB4,LGR4,SAT1,OSGIN2,ELF3,GABARAPL1,ADCK2,DAPK1,ACOX2,ATP1B3,NOTCH3,LRP11,ETV4,SULT2B1,SLC12A2,CTH,CYP1B1 |
| 3.182e-03 | -5.75 | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | 180 | 30 | 17758 | 1761 |
CCDC109B,FIGNL1,INPP5D,XYLT1,CALM1,TP53,LMCD1,FAM102B,CALM3,PBX3,ETS1,RNF19B,DCP2,RASGRP2,CALM2,AP1AR,DAZAP1,ADD3,PTEN,CDCA5,TMOD2,OSTF1,CYP2U1,RCAN3,TMEM159,UBE2C,MYL12B,CTDSP2,ESPL1,METAP2 |
| 3.182e-03 | -5.75 | STTTCRNTTT_V$IRF_Q6 | MSigDB lists | STTTCRNTTT_V$IRF_Q6 | 180 | 30 | 17758 | 1761 |
DDX58,PCGF5,SORBS1,KLHL13,PSME2,USP18,SYNE2,NUB1,TAP1,PSME1,OSR2,BCL2L1,IFIT3,PSIP1,LGALS3BP,NFIX,CDKN2C,CCND1,DTX3L,PITX2,TAPBP,C19orf66,MGAT4A,BHLHE41,NOD2,TRIM21,SFMBT1,NRG1,CITED2,NR3C2 |
| 3.182e-03 | -5.75 | REGULATION_OF_CELL_CYCLE | MSigDB lists | REGULATION_OF_CELL_CYCLE | 180 | 30 | 17758 | 1761 |
CCNE2,ZWINT,CDKN1C,TP53,HERC5,NUSAP1,RUNX3,PKMYT1,RAD17,ANLN,SESN1,CDK5R1,CCND1,CDKN2C,DIRAS3,CDK5RAP1,BTG3,PTEN,DHRS2,BMP7,MADD,DLG1,NEK2,CDKN1B,BUB1,CITED2,UBE2C,CDKN2D,CKS2,MAPK12 |
| 3.186e-03 | -5.75 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 942 | 119 | 17758 | 1761 |
GAS2L1,EXPH5,ARHGAP11A,MTM1,SPRED1,SORBS1,FAM92A1,PAPSS2,GRHL2,DLGAP5,S100A11,TRIP10,CNOT8,LMCD1,ERBB2,F11R,MORF4L2,ISOC2,RAD23A,APLP2,WEE1,RAB15,SCNN1A,CTGF,UBE2T,CDH1,METTL7A,DPYSL2,TSPAN6,CYP2S1,SLC44A1,TUBG1,ACSL4,EGLN3,TIAM1,DVL2,CKS2,CYP1B1,ING1,SEPT6,FOXJ2,CASP9,NUSAP1,ROR1,RAB38,DNAJB14,PKMYT1,SAV1,ICMT,KCTD2,ALCAM,ADRBK2,CDK1,COL12A1,FZD7,ARF4,DPYSL3,GDE1,GNPTAB,PEX2,PRKCDBP,KLF5,GLA,ZNF701,PRSS8,IER5L,CDK17,GOLIM4,PPP1R2,GGA1,TMEM55B,SDC4,PDCL,ASAH1,COL4A5,SLC36A4,SEPP1,DHRS3,FBLN1,PPP2R3A,TMEM63A,AKIRIN1,TOP2A,ADD3,CA2,CYR61,CDK16,ZNRF2,CALD1,BMP7,SGK3,FXYD5,SGK1,TNFRSF12A,IGFBP2,CITED2,IGDCC4,NFE2L3,PSMB4,MICB,BCL9,AK4,COL7A1,EPHA1,TCEAL8,RASA1,PITX2,CACHD1,SERPINA1,FGFR2,PRCP,HNRNPH2,AURKA,PPP2R3C,MDH1,OSR1,WDR62,KLF7,JARID2 |
| 3.198e-03 | -5.75 | neural crest cell differentiation | biological process | GO:0014033 | 75 | 16 | 16441 | 1675 |
SEMA6B,HES1,RET,SOX9,FGF19,EFNB1,EDNRA,PITX2,SEMA4D,CORO1C,NRG1,TWIST1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 3.198e-03 | -5.75 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological process | GO:0002479 | 75 | 16 | 16441 | 1675 |
SEC61B,PSMB4,HLA-E,PSME2,HLA-F,TAP1,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,TAPBP,HLA-B,PSMD1,HLA-C,ITGAV |
| 3.202e-03 | -5.74 | RB_P130_DN.V1_UP | MSigDB lists | RB_P130_DN.V1_UP | 127 | 23 | 17758 | 1761 |
RASGRF1,FADS2,SEMA6B,KIF20A,CHCHD7,CRB3,ADCK3,LITAF,SPATA13,STMN3,MRAS,B4GALT4,GRTP1,SNN,CDK1,CMTM7,IER3,SNTA1,FAM64A,AURKA,CCNB2,UBE2C,PCSK5 |
| 3.229e-03 | -5.74 | PID_P73PATHWAY | MSigDB lists | PID_P73PATHWAY | 77 | 16 | 17758 | 1761 |
SIRT1,CCNE2,BIN1,PLK1,ITCH,GDF15,CCNB1,S100A2,TP53I3,CDK1,FAS,SERPINA1,JAK1,BAX,MAPK11,BUB1 |
| 3.230e-03 | -5.74 | BASSO_CD40_SIGNALING_UP | MSigDB lists | BASSO_CD40_SIGNALING_UP | 98 | 19 | 17758 | 1761 |
NFKBIE,TRIP10,HLA-F,TAP1,LITAF,CR2,SNN,CD40,LHFPL2,TNFSF9,CD83,IER3,MAPKAPK2,KCNN4,NFKBIA,PIK3CD,ICOSLG,PTPRE,EHD1 |
| 3.237e-03 | -5.73 | CD82 (CD82 molecule) | protein interactions | 3732 | 41 | 11 | 16036 | 1726 |
ITGA3,VANGL1,CD63,AMFR,ITGA6,CD9,ERBB2,IGSF8,ERBB3,PTGFRN,LGALS3BP |
| 3.240e-03 | -5.73 | PLC-gamma1 signalling | REACTOME pathways | R-HSA-167021 | 36 | 10 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 3.240e-03 | -5.73 | EGFR interacts with phospholipase C-gamma | REACTOME pathways | R-HSA-212718 | 36 | 10 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 3.241e-03 | -5.73 | dystrophin-associated glycoprotein complex | cellular component | GO:0016010 | 21 | 7 | 17570 | 1756 |
SNTA1,SGCE,SNTB1,SGCB,DAG1,SNTB2,UTRN |
| 3.246e-03 | -5.73 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | 188 | 31 | 17758 | 1761 |
DDX58,SMARCA2,ING1,HPS3,ALDH6A1,ZNF395,FAM102B,PBX3,EIF2AK1,FBXO6,MGST2,CAMK1D,DOCK5,MFSD7,HLA-A,PRIM1,FECH,HLA-B,FAM111A,PRCP,CORO1C,CYP2S1,PGRMC1,NOD2,DUSP10,IRF2,TRIM21,CNPY3,TRAM1,CPPED1,PARP9 |
| 3.246e-03 | -5.73 | GSE3982_EOSINOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_DN | 188 | 31 | 17758 | 1761 |
PLK1,CMAS,MMD,IL15RA,VANGL1,PCBP3,PLEKHO1,PTTG1,NUSAP1,IL27RA,GPSM2,DHRS3,C11orf95,OPTN,APOBEC3B,DNAJC10,TAF1B,DCK,DLG1,PRKCDBP,GOT1,MDFIC,MDH1,MANF,MINPP1,LMAN1,TBC1D4,LTA4H,NR2C1,MPHOSPH9,ACOT7 |
| 3.246e-03 | -5.73 | V$FOXD3_01 | MSigDB lists | V$FOXD3_01 | 188 | 31 | 17758 | 1761 |
CYP26B1,FRMD4A,CHCHD7,NR4A1,SLC39A8,CAST,ETV5,RGAG1,UTRN,SYTL2,NEO1,NFIX,IER3,RALGPS2,KLF12,RNF128,CYR61,COL13A1,NPNT,CALD1,LMO4,SLC44A1,BCL6,SGK1,TWIST1,TACSTD2,DIXDC1,PRIMA1,CITED2,TOB1,CKAP4 |
| 3.246e-03 | -5.73 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 188 | 31 | 17758 | 1761 |
BIN1,SYPL1,GCA,SLC25A24,ING1,INPP5D,CXorf57,CR2,ARHGDIB,KIF13A,SNN,TRIB2,RASGRP2,ARHGAP24,ENDOD1,FAM111A,ADD3,RPL12,FRY,SLC4A4,DCK,CSF1,RPL39,FAM13B,AIM1,SORL1,RFX5,PIK3CD,CDKN2D,SNX10,PKIA |
| 3.246e-03 | -5.73 | GSE7460_TCONV_VS_TREG_LN_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_UP | 188 | 31 | 17758 | 1761 |
SSH3,MBP,LMTK3,EPAS1,RGMB,DAP,ATP1B1,SNN,DSE,SEPP1,FAM101B,DENND2D,KREMEN1,SH3KBP1,RASGRP2,XKRX,ACVRL1,FAAH,TRIM69,LMO4,CYP2S1,NR4A3,UBE2J1,DUSP10,TAGLN2,HS3ST3B1,RAB27B,ST3GAL1,ALS2CL,SLC16A5,PAQR7 |
| 3.246e-03 | -5.73 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 188 | 31 | 17758 | 1761 |
PGM1,AVPI1,KIAA1462,ENO2,HJURP,IFITM3,C5orf30,PKP2,GLO1,NPHP3,TP53INP2,FAM46C,TNFSF9,PPP2R3A,FZD7,FRMD4B,IER3,NEIL1,HPSE,ACVRL1,H1F0,MFSD2A,P4HA2,REEP1,AIM1,TLE1,UACA,EGLN3,SNX10,C9orf72,CTH |
| 3.246e-03 | -5.73 | V$HFH4_01 | MSigDB lists | V$HFH4_01 | 188 | 31 | 17758 | 1761 |
CYP26B1,TGIF1,NFKBIE,CPEB4,SPATA18,CHCHD7,FAM134A,RGAG1,CYP26A1,NEO1,GABARAPL1,FOXP2,CCND1,ITGA3,ANKS1B,TIMM8A,COL13A1,SLC44A1,KLF3,MITF,BCL6,NR4A3,ADAMTS14,SGK1,TWIST1,TSPAN13,NRG1,CACNA1D,CITED2,REEP4,RNF146 |
| 3.246e-03 | -5.73 | GSE7460_TREG_VS_TCONV_ACT_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_UP | 188 | 31 | 17758 | 1761 |
CPD,MYL9,LMO7,CCDC109B,RUNX2,PLSCR1,ITGA6,SDC4,NDUFA4,TGFBR1,GGH,HMGN3,ERBB2IP,CD274,BCL2L1,DUSP4,KLHL2,PIAS3,ZFYVE16,SIPA1L2,RAB11FIP2,PRICKLE3,SLC44A1,LRIG1,SNX16,YOD1,EFNA5,NFKBIZ,GEM,FAIM,TIAM1 |
| 3.259e-03 | -5.73 | autonomic_ganglia | COSMIC cancer mutations | autonomic_ganglia | 4170 | 459 | 17775 | 1757 |
ACACB,GAA,PPP4R4,ADD1,SSH1,HSPG2,AASS,AK7,VANGL1,ATP8A1,DNAJC3,RET,PPFIBP2,DHX8,FAM102B,VASH1,DPP8,GRM5,CALM2,CDKN2C,CYP1A1,PSMD1,ANKS6,MUC4,CTGF,PRICKLE3,OSBPL3,IL31RA,AOX1,KCNS3,PIK3CA,RCAN3,TIAM1,LAMP2,NWD1,ORAI2,KIFC2,ACVR1C,SH3BGRL,SERTAD4,KIF13A,CCNF,SPNS3,POR,COL12A1,ARHGEF26,AHRR,ENPP1,PLCG1,RBM47,DNM1L,FAM114A1,BMP1,DHTKD1,NFKBIZ,SERPINI1,UNC5B,DDX58,SEMA6B,SCN5A,FAM169A,TBC1D1,ITGA6,MERTK,MESDC2,MECOM,RABGGTA,DOPEY2,FRY,ITGA3,PIK3AP1,RIMS3,MEGF8,SLC16A6,AIM1,PRKG1,SORL1,CADPS2,C8orf58,PIKFYVE,ZMYM1,NCAM1,DGKG,NUP85,RIMS2,GPR161,DDB2,B3GNT7,FADS2,KCNJ12,KLK5,HPS3,SLC37A1,PRSS23,KIF20A,TBC1D8B,SALL4,MICB,STAT4,AMER1,PIP4K2C,NPC2,ATP8B3,PLIN5,STX3,RASA1,FRMD4B,STK17A,DGKH,CACHD1,NCOA3,SLCO4A1,AP1AR,PLEKHH2,TJP3,SLC4A4,ISM1,DCK,ITPR1,SLC4A3,FAM83D,AGBL5,FGD6,CABIN1,NR4A2,DRP2,ARPC2,PER3,IFIH1,XDH,DOCK9,PLA2G4A,CCDC109B,SLC2A4,GRHL2,NQO1,CEP70,TRIP10,ST14,ACTR8,IQGAP1,RALBP1,ATP2C2,PKP2,IL13RA1,SNN,AIFM2,ZFYVE9,MUC16,ZNF75D,ST5,SP100,TRANK1,SH3BP1,DACT1,CNNM4,PHKA2,RAB27B,LRP11,CDKN2D,NR2C1,MYO5B,DOCK4,ENPP4,SSH3,COG2,FOXJ2,SYNE2,UTRN,TMEM144,CDCA2,SLC11A2,PRKCQ,PYGO1,C15orf39,ITPR3,FZD7,AMZ2,DDOST,CCDC149,AXL,PNPLA6,NR3C2,COBL,ISOC1,TNRC6C,CENPI,CTSZ,NUCB2,DNAH3,SLC25A43,HLA-A,NEO1,E2F7,FAM111A,ADD3,RNF128,ARSG,PTEN,CALD1,ALG13,ATP8B1,WWP1,MAPK11,ERBB3,TRIM62,TPCN1,NCOA2,OSGIN1,ACBD5,AMOTL2,ADAMTS2,RASGRF1,PDGFC,ZWINT,ARAP2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PARP4,DIAPH2,FBXO9,SNTB1,CNTNAP1,PITX2,ACADSB,PLOD2,FGFR2,ACVRL1,TBX18,AMMECR1,ABCB1,PGM2L1,GRIN2D,ETAA1,WDR62,FZD5,CPEB2,ESPL1,DEF6,OCLN,MELK,TLL2,TMEM131,JARID2,EXPH5,UNKL,LTBP1,UGT8,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,TMC1,FANCI,ABCD4,CHPF,SUSD2,ARHGEF10L,SIPA1L2,HSF2,SHC3,NPNT,MKRN3,MITF,ABCA2,POF1B,MYH14,SLC39A10,TLN2,MYRIP,MYBL1,NEB,RASGRP1,ZNF462,PLK1,ING1,CELSR2,RGAG1,EZR,CR2,ARHGDIB,IDH1,DZIP1L,DPYSL3,CXXC4,MAN2A2,PLEKHG6,PLCH1,MFAP3L,NEIL1,HPSE,MAP2,MADD,PIK3C2B,CAPN1,PCSK5,PRKAA2,SERPINE2,PEX6,PYROXD2,ADCK5,CNTNAP2,DHRS3,FBLN1,TNS3,FRAS1,KCNN4,COL6A1,HLA-C,ZRANB1,NCEH1,WNT3A,LRIF1,PLCB2,ALS2CL,CCDC88A,KDELR1,DPYSL5,PODXL2,PLEKHA6,TESK1,OXR1,SPATA13,VWA1,BTN3A2,STRADB,SCRIB,HEATR5A,C3orf58,MUM1L1,PRX,SOX13,GNAS,MAPKAPK2,ONECUT1,COL13A1,TMEM30A,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,AFAP1,RNF146,PROM2,USP43,KLF7,LMO7,NCKAP5,NF2,TP53,PDIA5,ERBB2,TDRKH,STIL,PDGFA,SS18,SLC25A48,ZNF687,WDR44,FRYL,PLCG2,PLK4,NOTCH3,OAS3,F2R,DVL2,FRS3,CTH,SUSD3,GCA,CLCN3,AKT1,PTGER4,FANCE,DOCK5,DAG1,DUOX1,TAPBP,IDE,PRRT4,BFSP1,C19orf66,ADAMTS14,TLE1,ABCA1,NDST3,PPP2R2D,ZMAT1,GLIS3,CMAS,PACSIN2,GOLIM4,CPEB4,ARHGEF11,LRP4,HAL,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,SLC9A2,NRP2,FZD6,DNAJB9,SIRPA,TMEM63A,FOXP2,IRF2BPL,LLGL2,A4GALT,BMP7,FAM63A,KIAA0319,ARVCF,SGK1,TSPAN13,ABCD1,ALDH7A1,MYO5A,TLE6,RBMS2,ATP2B1,PLAUR,ASPM,LITAF,MBNL3,TTC7A,MAML2,COL7A1,LEPR,CD83,FAT4,SCG2,PRCP,TMC5,CDCA7L,DTX4,FAM117A,GRAMD1C,HOXB13,ICOSLG,UBE2C,NDFIP1,HIPK3,ARHGEF9,L1CAM,AHR,ARHGEF4,GOLGB1,DIS3L,CD33 |
| 3.266e-03 | -5.72 | TRPC4 (transient receptor potential cation channel, subfamily C, member 4) | protein interactions | 7223 | 15 | 6 | 16036 | 1726 |
MX1,TRPC1,ITPR2,ITPR3,ITCH,ITPR1 |
| 3.266e-03 | -5.72 | WNK4 (WNK lysine deficient protein kinase 4) | protein interactions | 65266 | 15 | 6 | 16036 | 1726 |
KLHL2,SGK1,CLDN4,STK39,AKT1,BCL6 |
| 3.266e-03 | -5.72 | AKAP5 (A kinase (PRKA) anchor protein 5) | protein interactions | 9495 | 15 | 6 | 16036 | 1726 |
PRKAR2B,PRKACA,IQGAP1,CALM1,RET,DLG1 |
| 3.268e-03 | -5.72 | BOYLAN_MULTIPLE_MYELOMA_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_UP | 84 | 17 | 17758 | 1761 |
SUSD3,PRODH,PRSS23,SERTAD4,ITGA6,BLVRB,PM20D2,NFIX,CCND1,PLK2,CLMN,SH3BGRL2,KLF9,TLN2,HSPB1,AFAP1,NIPA1 |
| 3.268e-03 | -5.72 | KEGG_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_SMALL_CELL_LUNG_CANCER | 84 | 17 | 17758 | 1761 |
CCNE2,AKT1,ITGA6,CASP9,PIK3R1,TP53,BCL2L1,PIAS3,CCND1,ITGA3,PTEN,NFKBIA,PIK3CA,CDKN1B,ITGAV,PIK3CD,TRAF5 |
| 3.269e-03 | -5.72 | PNT | prosite domains | PS51433 | 11 | 5 | 11866 | 1235 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 3.269e-03 | -5.72 | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN | MSigDB lists | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN | 57 | 13 | 17758 | 1761 |
NOV,IQGAP1,SAT1,ADAM15,AES,CTSZ,PSMA4,SYK,SP4,PDIA4,WBP5,SOCS3,RASGRP2 |
| 3.269e-03 | -5.72 | PID_TXA2PATHWAY | MSigDB lists | PID_TXA2PATHWAY | 57 | 13 | 17758 | 1761 |
RHOA,ADRBK1,GNB5,AKT1,PRKG1,PRKCQ,MAPK11,YES1,PLCB2,PRKACA,ADRBK2,GNA11,SYK |
| 3.270e-03 | -5.72 | Znf_NHR/GATA | interpro domains | IPR013088 | 57 | 13 | 18293 | 1814 |
THRB,NR3C1,GATA2,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 3.273e-03 | -5.72 | Alzheimers Disease | WikiPathways | WP2059 | 79 | 18 | 4455 | 516 |
CASP3,CALM1,CASP9,TP53,GRIN1,CALM3,ITPR2,ITPR3,CDK5R1,FAS,CALM2,IDE,ITPR1,GRIN2D,CACNA1D,PLCB2,CAPN1,CHP1 |
| 3.278e-03 | -5.72 | mammary gland development | biological process | GO:0030879 | 124 | 23 | 16441 | 1675 |
AKT1,SOX9,ERBB2,TFAP2C,SCRIB,DDR1,ELF3,IRS2,CCND1,NCOA3,IGF1R,FGFR2,HOXA9,CSF1,ATP7B,ELF5,NRG1,WNT3A,USF2,SLC12A2,ETV4,CAPN1,XDH |
| 3.279e-03 | -5.72 | Endometrial cancer | KEGG pathways | hsa05213 | 52 | 13 | 6908 | 758 |
CCND1,AKT1,CDH1,PTEN,PIK3R1,CASP9,TP53,PIK3CA,ERBB2,TCF7,PIK3CD,ELK1,APC2 |
| 3.279e-03 | -5.72 | Endometrial cancer | KEGG pathways | ko05213 | 52 | 13 | 6908 | 758 |
CCND1,AKT1,CDH1,PTEN,PIK3R1,CASP9,TP53,PIK3CA,ERBB2,TCF7,PIK3CD,ELK1,APC2 |
| 3.287e-03 | -5.72 | INTRINSIC_TO_MEMBRANE | MSigDB lists | INTRINSIC_TO_MEMBRANE | 1288 | 157 | 17758 | 1761 |
LAMP1,BCAM,SLC25A13,EPHA4,SDC1,SLC20A1,SLC9A7,GRM5,HTR1D,ABCD4,STIM1,IL6ST,SLC44A1,STEAP2,FUT1,ABCA2,CLDN4,TRPC1,TACSTD2,TRAM1,SGCE,CD55,MCTP1,ACVR1C,ROR1,SLC25A5,EDNRA,HS6ST1,ENPP1,KCNMB4,SLC25A4,GDE1,KCNK1,DOLPP1,ATP7B,MADD,F2RL1,CD99,FXYD3,ABCG2,B4GALT4,MERTK,TSPAN7,ITGA3,LYPD3,SLC16A6,KCNN4,OPN3,FXYD5,SORL1,CD70,NCAM1,SLC12A2,CKAP4,KDELR1,ABCC1,FADS2,PODXL2,PCDH1,MFI2,MMD,RGMB,EPHA1,STEAP1,PTPRF,GNAS,MMP15,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,ATP1B3,SLC2A4,IL15,ST14,CD82,PKP2,IL27RA,IL13RA1,SLC7A2,EMP2,DDR1,BCAP31,ATP6V0B,VAT1,NOTCH3,EPHB4,ECE1,LMAN1,TSPAN1,F2R,CLCN3,FZD4,PTPRU,PTGER4,SLC11A2,IGSF8,ATP1B1,CD40,DAG1,FZD7,TAPBP,PTPRJ,ATP1A1,PTK7,WFS1,AXL,SLC9A6,MMP17,PEX2,SECTM1,EFNA5,HS3ST3B1,LIFR,ABCA1,GOLIM4,CD63,TSPAN15,GABRG2,SELL,CYB561,TGFBR1,SBF1,EFNB1,LBR,SLC9A2,FZD6,M6PR,NEO1,IL17RB,ADORA1,ITGB8,BAX,SLC44A2,TMBIM6,TSPAN13,ERBB3,SGCB,SLC16A5,ATP2B1,GCNT1,SYPL1,MPP1,AMFR,GRIN1,CD83,CNTNAP1,GALNT3,ACVRL1,SPINT2,PGRMC1,RYK,ABCB1,FZD5,GOLGB1,CD33 |
| 3.296e-03 | -5.71 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | 165 | 28 | 17758 | 1761 |
GCLM,TXN,GNPDA1,RAPGEF2,PLAUR,OSGIN2,IL18,CD274,SAV1,CDK1,RHEB,SCML1,IER3,SLCO4A1,E2F7,ETS2,MFSD2A,CSF1,UBE2J1,SELK,NFKBIZ,PLD1,GLA,GEM,EGLN3,SPRY2,ATP2B1,CKS2 |
| 3.296e-03 | -5.71 | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | MSigDB lists | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | 165 | 28 | 17758 | 1761 |
TIMP2,FZD4,PLAUR,CAST,EPHA4,ERBB2,COL18A1,IL18,TGFBR1,EPHA1,PDGFB,EFNB1,NRP2,FZD6,FZD7,EPHA10,PGF,PDGFA,TIMP3,HPSE,PTEN,CYR61,FGFR2,IL6ST,ERAP1,EGFL7,ITGAV,F2R |
| 3.297e-03 | -5.71 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 196 | 32 | 17758 | 1761 |
GAA,ENO2,UGP2,CDKN1C,SDC4,PDGFB,ETS1,IER3,CTGF,CYR61,ZFP36,CDKN1B,PIM1,CITED2,TIPARP,SULT2B1,B3GALT6,PGM1,NR3C1,S100A4,PLAUR,AK4,PDK3,FOS,PGF,IRS2,SLC6A6,P4HA2,PRKCDBP,MAFF,RRAGD,KLF7 |
| 3.297e-03 | -5.71 | GSE17721_12H_VS_24H_LPS_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_LPS_BMDM_UP | 196 | 32 | 17758 | 1761 |
CCDC109B,PARP12,S100A11,RASA2,ABCG2,DNAJB11,TGFBR1,PSME1,GRK6,RCN1,APLP2,RPS6KA2,ITGA3,KCNN4,SGK3,MDFIC,CTTN,ECE1,CORO2A,KIF1C,KLK6,IFIT3,FNDC3A,SAV1,CASP4,NCOA3,KBTBD2,NFKBIA,OVOL1,SERPINB6,ITGAV,RGS14 |
| 3.297e-03 | -5.71 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 196 | 32 | 17758 | 1761 |
TXN,S100A11,EFHD2,FAM46C,IL18R1,FGF19,HLA-A,DAPK2,WEE1,FOSB,SORL1,MDFIC,PIM1,TMEM37,F2R,SNX10,S100A13,S100A6,PLSCR1,S100A4,SNTB2,GGH,YES1,RNF19B,FOS,DOCK5,CASP4,NUCB1,H1F0,TOB1,ACOT7,XDH |
| 3.297e-03 | -5.71 | GSE339_CD4POS_VS_CD8POS_DC_UP | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_UP | 196 | 32 | 17758 | 1761 |
BIN1,LASP1,ARHGEF3,NLRX1,ARL4C,DHRS3,TNFRSF19,MNS1,LBR,B4GALNT1,RGS3,FAM13B,DLG1,ABCA2,NDUFA12,GCNT1,MAP3K3,SMARCA2,RHOA,USP18,NR4A1,GGH,CCNF,SESN1,SOX13,COL13A1,STK38,ABCB1,CTSA,SERPINI1,RGS14,LTA4H |
| 3.299e-03 | -5.71 | Regulation of Microtubule Cytoskeleton | WikiPathways | WP2038 | 44 | 12 | 4455 | 516 |
MAPKAPK2,SPRED1,AKT1,PTEN,DPYSL2,LIMK1,PIK3CA,TESK2,WNT3A,TIAM1,PRKACA,CDK1 |
| 3.307e-03 | -5.71 | AKT1 (v-akt murine thymoma viral oncogene homolog 1) | protein interactions | 207 | 285 | 46 | 16036 | 1726 |
CASP3,PINK1,ENO2,NF2,CDKN1C,CAMKK1,IQGAP1,BCL2L1,PLXNA1,PHLPP1,APLP2,GATA2,PTEN,PIK3CA,CDKN1B,DAB2IP,ERBB3,CCDC88A,SIRT1,PSMB4,AKT1,NR4A1,SERTAD4,CASP9,CALM1,PLEKHO1,PIK3R1,RGCC,ACO1,IGSF8,PRKCQ,ITPR3,MAPK8IP1,JADE1,MAPKAPK2,PLCG1,CARHSP1,ATP1A1,ITPR1,FAM110C,ARRB1,MDH1,FHL1,MAP3K5,TBC1D4,HSPB1 |
| 3.313e-03 | -5.71 | establishment or maintenance of cell polarity | biological process | GO:0007163 | 146 | 26 | 16441 | 1675 |
CENPA,FRMD4A,ARHGEF11,SYNE2,NDC80,EZR,SCRIB,MPP5,GPSM2,NCKAP1,ERBB2IP,NPHP3,ARF4,LMNA,FRMD4B,WEE1,IGF1R,LLGL2,RAB11FIP2,PTK7,SPINT2,DLG1,DLG3,ARF6,NDE1,SPRY2 |
| 3.316e-03 | -5.71 | maintenance of protein location in cell | biological process | GO:0032507 | 82 | 17 | 16441 | 1675 |
SUN1,SUN2,PINK1,NFKBIE,AKT1,THRA,SYNE2,PSMD10,PDIA3,EZR,DAG1,NFKBIA,SORL1,SUN3,TLN2,KDELR1,MDFI |
| 3.321e-03 | -5.71 | human chr7p12.1 | chromosome location | human chr7p12.1 | 5 | 3 | 26250 | 1887 |
FIGNL1,SEMA3A,COBL |
| 3.321e-03 | -5.71 | human chr1p35-p34 | chromosome location | human chr1p35-p34 | 5 | 3 | 26250 | 1887 |
TMEM54,FAAH,COL16A1 |
| 3.325e-03 | -5.71 | positive regulation of peptidyl-threonine phosphorylation | biological process | GO:0010800 | 26 | 8 | 16441 | 1675 |
PLK1,CALM2,PRKAG2,RIPK2,BMP7,CALM1,CAB39,CALM3 |
| 3.325e-03 | -5.71 | lung epithelial cell differentiation | biological process | GO:0060487 | 26 | 8 | 16441 | 1675 |
THRB,GRHL2,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB |
| 3.334e-03 | -5.70 | GTPase regulator activity | molecular function | GO:0030695 | 286 | 44 | 16491 | 1673 |
ARHGAP11A,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,RALBP1,IQGAP1,ARFGEF1,RGS20,GPSM2,SIPA1L2,ACAP2,LLGL2,RINL,SH3BP1,RGS3,TBCD,FAM13B,RANBP1,DAB2IP,RP2,IQGAP3,ALS2CL,DOCK4,ARAP2,TBC1D8B,RAPGEF2,ARHGDIB,GRTP1,ABR,RASA1,ARHGAP35,ARHGAP24,PLEKHG6,ARHGEF19,SIPA1L1,SH3BP4,ARRB1,AGFG2,RGS14,TBC1D4,RAP1GAP,CPEB2 |
| 3.335e-03 | -5.70 | PPP1CC (protein phosphatase 1, catalytic subunit, gamma isozyme) | protein interactions | 5501 | 240 | 40 | 16036 | 1726 |
TPRN,ENO2,PPP1R2,NUAK1,RASSF7,NDC80,TP53,NUF2,BCL2L1,FBXO6,CCNB1,HDAC6,LBR,ZFYVE9,LMNA,RASSF8,ZFYVE16,CCND1,DPYSL2,DACT1,NEK2,SGCE,AKT1,CDCA2,TNS1,SCRIB,LRRC1,ERBB2IP,RNF19B,CDK1,RANBP9,KDM4D,CTSL,AURKA,HDAC1,CLMN,ZDBF2,TMEM120A,TANC2,NRBP1 |
| 3.335e-03 | -5.70 | PRKACA (protein kinase, cAMP-dependent, catalytic, alpha) | protein interactions | 5566 | 240 | 40 | 16036 | 1726 |
ADD1,TRIP10,IQGAP1,DCAF7,ITPR2,CCND1,ADRBK1,CDK16,CALD1,IRF2,PDE4D,GAD1,APOBEC3G,NUP85,CCDC88A,GPR161,ATP2B1,MAP3K3,RASGRF1,KCNJ12,MBP,RHOA,NR3C1,GUSB,ITCH,PRKAR2B,FOS,RANBP9,NIN,SLC4A4,MAP2,ITPR1,AURKA,HDAC1,ARPC2,RGS14,ITPKA,RAP1GAP,ABCA1,PKIA |
| 3.339e-03 | -5.70 | Activation of NIMA Kinases NEK9, NEK6, NEK7 | REACTOME pathways | R-HSA-2980767 | 7 | 4 | 8202 | 867 |
PLK1,CCNB1,CCNB2,CDK1 |
| 3.345e-03 | -5.70 | positive regulation of mononuclear cell proliferation | biological process | GO:0032946 | 117 | 22 | 16441 | 1675 |
HES1,CD55,RIPK2,IL15,HLA-E,IL18,PRKCQ,CD274,CD40,TNFSF9,EFNB1,HLA-A,IRS2,IL6ST,CSF1,BCL6,IGFBP2,SLC39A10,ICOSLG,WNT3A,JAK3,SYK |
| 3.360e-03 | -5.70 | regulation of axonogenesis | biological process | GO:0050770 | 161 | 28 | 16441 | 1675 |
SSH3,SEMA6B,RHOA,SSH1,LRP4,RET,EPHA4,GRIN1,PLXNA1,CRABP2,CDK5R1,PTEN,SEMA4D,DPYSL2,LIMK1,KIF13B,MEGF8,SIPA1L1,TNFRSF12A,EFNA5,NRG1,CTTN,SEMA3G,WNT3A,SEMA3A,TIAM1,L1CAM,SEMA3B |
| 3.360e-03 | -5.70 | INTRACELLULAR_SIGNALING_CASCADE | MSigDB lists | INTRACELLULAR_SIGNALING_CASCADE | 659 | 87 | 17758 | 1761 |
CASP3,SPRED1,NF2,RALBP1,TP53,MRAS,BCL2L1,SLC20A1,CARD10,GRM5,HTR1D,ARHGEF10L,DAPK2,RPS6KA2,TSPAN6,RGS3,IL31RA,DUSP10,F2R,MED30,RASGRP1,MAP3K3,RIPK2,AKT1,CASP9,PTGER4,PRKAR2B,ARHGDIB,RAD17,DUSP4,CD40,MAP3K6,STK17B,ABR,EDNRA,SOCS3,PLCH1,CARHSP1,DNM1L,PLK2,LIMK1,STK38,SECTM1,MADD,NOD2,ADIPOR1,ARF6,TRAF5,AIFM3,ABCA1,FGD1,PINK1,ARAP3,PKN1,DIRAS3,TOP2A,CARD8,PTEN,BAX,MAP3K9,DAPK1,SLC44A2,MAPK11,MDFIC,PIKFYVE,PLCB2,FARP2,MDFI,RHOA,STAT4,CORO2A,AMFR,LITAF,MAPK8IP1,STK17A,PRDX4,GNAS,MAPKAPK2,SCG2,NMI,NR4A3,FGD6,PLD1,MAP3K5,NDFIP1,IFI6,ZBTB33 |
| 3.364e-03 | -5.69 | regulation of actin filament-based process | biological process | GO:0032970 | 317 | 48 | 16441 | 1675 |
SCN5A,NF2,SSH1,ADD1,FRMD6,EPS8,SDC4,ARFGEF1,PKP2,F11R,NCKAP1,SPTB,SNTA1,PDGFA,CTGF,DLG1,DIXDC1,TACSTD2,PDE4D,CTTN,NEB,CCDC88A,SSH3,RHOA,FMN1,PIK3R1,PTGER4,RGCC,EZR,PRKCQ,EPHA1,CDK5R1,RASA1,AP1AR,ATP1A1,SWAP70,PLEKHH2,ARHGEF19,LIMK1,CTSV,TRIOBP,EFNA5,TMOD2,SPTBN5,ARPC2,ARF6,SHROOM2,F2RL1 |
| 3.366e-03 | -5.69 | actin-based cell projection | cellular component | GO:0098858 | 164 | 28 | 17570 | 1756 |
DOCK4,TPRN,MTM1,NF2,MPP1,EPS8,SYNE2,EPHA4,ARL4C,SPATA13,UTRN,ERBB2,EZR,ANTXR1,TMC1,DAG1,PLS3,PDGFA,ITGA3,CA2,CTSV,AKR1B1,ATP8B1,ESPN,ITGAV,ARF6,MYO5A,PROM2 |
| 3.375e-03 | -5.69 | LYSASSOCTDMP | prints domains | PR00336 | 4 | 3 | 4759 | 462 |
LAMP2,LAMP1,LAMP3 |
| 3.384e-03 | -5.69 | CASP1 (caspase 1) | protein interactions | 834 | 53 | 13 | 16036 | 1726 |
PLA2G4A,CARD8,RIPK2,CAST,TFAP2A,NOD2,IL18,BCL2L1,KIF11,GAB1,BCAP31,CASP4,LMNA |
| 3.388e-03 | -5.69 | RAO_BOUND_BY_SALL4 | MSigDB lists | RAO_BOUND_BY_SALL4 | 220 | 35 | 17758 | 1761 |
SPRED1,TM2D2,TRIM2,TTC39B,TSPAN15,HEXB,TP53,RGS20,IRF2BPL,WEE1,CTGF,IL6ST,FLRT3,FRYL,SLC44A1,CST3,TMEM64,SPRY2,CCDC38,SULF2,PDGFC,ZWINT,SNTB2,LYRM1,TFAP2C,RAB38,PTGFRN,IDH1,DGKH,FGFR2,STK38,ZNF704,F2RL1,COBL,JARID2 |
| 3.389e-03 | -5.69 | maintenance of protein location | biological process | GO:0045185 | 89 | 18 | 16441 | 1675 |
SUN1,SUN2,LTBP1,PINK1,NFKBIE,AKT1,THRA,SYNE2,PDIA3,PSMD10,EZR,DAG1,NFKBIA,SORL1,SUN3,TLN2,KDELR1,MDFI |
| 3.389e-03 | -5.69 | regulation of protein complex disassembly | biological process | GO:0043244 | 89 | 18 | 16441 | 1675 |
GAS2L1,ADD1,CKAP2,EPS8,EIF5A2,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2,F2RL1 |
| 3.400e-03 | -5.68 | V$BRN2_01 | MSigDB lists | V$BRN2_01 | 228 | 36 | 17758 | 1761 |
TXN,ETV5,ZNF385B,MECOM,CCND1,CTNNBIP1,FOXP2,MDM1,ANKS1B,FLRT3,SGK3,STEAP2,DUSP10,TSPAN13,PIM1,IQGAP3,PLCB2,MYT1,ETV4,PDGFC,BCL9,SNTB2,SAT1,ANLN,FOS,COL12A1,EDNRA,KLF12,FGFR2,NR4A3,ZMIZ1,ARF6,HOOK1,TOB1,NDST3,NR3C2 |
| 3.400e-03 | -5.68 | V$TCF4_Q5 | MSigDB lists | V$TCF4_Q5 | 228 | 36 | 17758 | 1761 |
CTHRC1,TM2D2,SORBS1,HOXB7,COL18A1,TNFRSF19,SIX4,NRP2,SYTL2,TFAP4,FOXP2,ANKS1B,BMP7,ELF5,ENPP5,MITF,SGK3,FAM63A,ABCD1,PIM1,TGIF1,PCDH1,ELK3,PLSCR1,PANK1,TCF7,RNF19B,STEAP1,CDK1,NFIX,CORO1C,NKD1,NR4A3,AGFG2,LIFR,TLL2 |
| 3.400e-03 | -5.68 | V$ER_Q6_02 | MSigDB lists | V$ER_Q6_02 | 244 | 38 | 17758 | 1761 |
SLC25A27,ARFGEF1,GABRG2,NDRG2,CRABP2,COX6C,C3orf18,CYP39A1,HPCAL4,SIRPA,CYP26A1,IRF2BPL,ITGB8,SH3BP1,SLC16A6,STEAP2,BCL6,TNFRSF12A,MANF,BTBD3,OSGIN1,CCDC88A,DOCK4,ELK3,FZD4,TFAP2C,TCF7,EPN3,PLEKHG6,FGFR2,MADD,RAP2C,ADAMTS14,FHL1,ST3GAL1,ZBTB33,HOXC13,NR2C2 |
| 3.400e-03 | -5.68 | V$PAX2_02 | MSigDB lists | V$PAX2_02 | 244 | 38 | 17758 | 1761 |
LASP1,TRIM2,FRMD4A,POC1B,ETV5,CACNA2D2,TGFBR1,MPP5,DNER,SLC20A1,DHRS3,SDC1,HOXB2,CCND1,FOXP2,SESN3,RNF220,SLC16A6,PRICKLE3,VASN,BCL6,TSPAN13,CITED2,TRIM8,RHOA,ELK3,CDC20,UBE2A,DUSP4,CD40,FOS,GLT8D2,NFIB,EPN3,NFKBIA,SERPINI1,OSR1,TOB1 |
| 3.404e-03 | -5.68 | V$AP2GAMMA_01 | MSigDB lists | V$AP2GAMMA_01 | 236 | 37 | 17758 | 1761 |
IER5L,SCN5A,GRHL2,CPEB4,SOX9,PKN1,PDGFB,DENND2D,SIX4,MECOM,NEO1,APLP2,RNF220,ZNF687,ARTN,ZNRF2,ATP5H,LMO4,LHX6,TRPC1,NOTCH3,ETV4,DGKG,KCNJ12,NR3C1,CBX6,MAP3K6,NFIB,SP4,CD83,PITX2,KLF12,PTK7,CTSA,RARG,JARID2,NR2C2 |
| 3.422e-03 | -5.68 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 384 | 55 | 17758 | 1761 |
HECA,TRIM2,RUNX2,CPEB4,RALBP1,LRP4,HABP4,C5orf30,MIER3,TESK2,TTYH3,SLC9A2,ZFYVE9,NRP2,M6PR,WEE1,E2F7,NPNT,DPYSL2,BHLHE41,ENPP5,FAM20B,SLC44A1,MAP3K9,ANKRD12,MDFIC,ACSL4,MARCH2,BTBD3,MYT1,PPP6R1,MPHOSPH9,CCDC88A,SOCS5,ACBD5,TIMP2,ELK3,SYBU,RUNX3,ERBB2IP,PTGFRN,ARHGAP35,MID1IP1,CDK19,CSNK1G1,CSF1,ITPR1,RAP2C,LRIG1,PGM2L1,SFMBT1,NR3C2,ABCA1,NIPA1,SNPH |
| 3.426e-03 | -5.68 | lipid metabolic process | biological process | GO:0006629 | 1158 | 146 | 16441 | 1675 |
ACACB,UGT8,HSPG2,CPT2,HEXB,TEX2,NANS,SDC1,CYP1A1,CTGF,GRHL1,CYP2S1,IMPAD1,ALDH1A3,SLC44A1,SERINC2,PIK3CA,ABCA2,AKR1B1,PIK3CD,ACOX2,TECR,TIPARP,CYP1B1,SLC35C1,PRKAR2B,IDH1,CYP4F3,POR,PLCH1,PLCG1,MID1IP1,AGPAT2,GDE1,DOLPP1,ADIPOR1,PIK3C2B,GLA,PRKAA2,FAM213B,TMEM55B,ASAH1,ISYNA1,B4GALT4,DHRS3,B4GALNT1,BDH1,SORL1,PIKFYVE,FAR2,NCEH1,PLCB2,ALDH3A2,ABCC1,CYP26B1,GFPT1,FADS2,PQLC3,LPGAT1,PIP4K2C,NPC2,NPHP3,PCTP,SPTLC2,FECH,MAPKAPK2,PRKAG2,UAP1,FAAH,PLPP3,PITPNA,CTSA,PLD1,APOL2,PLA2G4A,MTM1,INPP5D,MGST2,LPIN3,PRKACA,CYP39A1,CYP26A1,CDS1,APLP2,FABP6,PLCG2,ACSL4,LGMN,SULT2B1,NAGA,GM2A,GPX4,SIRT1,CYB5R2,ALDH3B1,ALDH5A1,ABHD12,PEX2,INPP4B,PNPLA6,SLC27A1,CYP2U1,SLC27A3,ST3GAL1,LTA4H,ABCA1,CMAS,SDC4,GNE,CRABP2,PLPPR4,LBR,SGPL1,SLC27A6,ITGB8,ADORA1,PTEN,ARSG,A4GALT,ALG13,BAX,SLC44A2,ECI2,ATP8B1,ABCD1,SYK,MYO5A,NCOA2,PLSCR1,PLAUR,ELOVL3,PIK3R1,PPARA,RNPEP,ARSK,LEPR,CPTP,DGKE,GPLD1,ACADSB,DHRS2,DBI,ARSB,PTGES,ACOT7,ABCG1 |
| 3.436e-03 | -5.67 | sulfur compound metabolic process | biological process | GO:0006790 | 366 | 54 | 16441 | 1675 |
SLC35D2,ACACB,GCLM,TXN,PAPSS2,HSPG2,AASS,XYLT1,HEXB,SDC4,MGST2,B4GALT4,DSE,SDC1,GSTP1,CHPF,GNS,ARSG,IMPAD1,XYLT2,PAPSS1,GALNS,TPST1,PCYOX1,GOT1,AHCY,ACSL4,FAR2,TECR,SULT2B1,MCCC2,CTH,SULF2,CHSY3,B3GALT6,OPLAH,B3GNT7,B3GNT2,GCLC,ELOVL3,GLO1,ICMT,IDH1,GLCE,HS6ST1,ENPP1,ALDH5A1,HPSE,HS3ST3B1,ARSB,ST3GAL1,NDST3,ACOT7,OCLN |
| 3.462e-03 | -5.67 | GSE12366_GC_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_UP | 181 | 30 | 17758 | 1761 |
GFPT1,PLK1,CASP3,SEC61B,SYNE2,SOX9,PANK1,LMCD1,PSMD10,VEZT,HMGN3,MGST2,ASB13,PSIP1,KCTD9,BCAR3,MAP2,CDCA5,NR4A3,BCL6,CENPE,CTTN,NCAPG2,UBE2C,NDUFA12,CCNB2,MPHOSPH9,ARHGEF9,ESPL1,SNX30 |
| 3.462e-03 | -5.67 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 181 | 30 | 17758 | 1761 |
DDX58,SSH3,GCLM,CMAS,SORT1,LPGAT1,XYLT1,SYNE2,TMX4,NUB1,UTRN,SELL,SAMD9,IFIT3,HERC6,FAM101B,ALCAM,DTX3L,PGF,IDE,TRANK1,ACADSB,C19orf66,TIMM8A,ZNRF2,METTL7A,PIK3CD,F2RL1,CRTAP,DEF6 |
| 3.463e-03 | -5.67 | Platelet activation | KEGG pathways | hsa04611 | 130 | 25 | 6908 | 758 |
PLA2G4A,RHOA,AKT1,PIK3R1,ITPR2,ITPR3,PRKACA,MYL12A,ARHGAP35,RASGRP2,GNAS,STIM1,PLCG2,ITPR1,PIK3CA,PRKG1,MAPK11,PIK3CD,TLN2,F2R,PLCB2,SYK,MYL12B,RASGRP1,MAPK12 |
| 3.466e-03 | -5.66 | negative regulation of cell cycle process | biological process | GO:0010948 | 238 | 38 | 16441 | 1675 |
CAST,PSME2,CTDSPL,PTTG1,TP53,PSMD10,PSME1,FANCI,IER3,SUSD2,CCND1,TFAP4,E2F7,PSMD1,RPS6KA2,PTEN,DACT1,BMP7,CDKN1B,DAB2IP,BUB1,CTDSP2,PLK1,PSMB4,CDC20,RGCC,CCNF,NUBP1,PSMA4,CDK1,JADE1,FGFR2,OVOL1,FHL1,GPER1,UBE2C,E2F8,ESPL1 |
| 3.474e-03 | -5.66 | negative regulation of Wnt signaling pathway | biological process | GO:0030178 | 184 | 31 | 16441 | 1675 |
CTHRC1,PSMB4,PSME2,AMER1,SOX9,LRP4,PRICKLE1,PSMD10,AES,PSME1,NOTUM,NPHP3,APC2,PSMA4,HMGXB4,FZD6,PPP2R3A,CTNNBIP1,CCND1,CXXC4,PSMD1,ANKRD6,DACT1,TBX18,NKD1,TLE1,TRABD2A,DAB2IP,WNT3A,DVL2,MDFI |
| 3.486e-03 | -5.66 | CASTELLANO_NRAS_TARGETS_UP | MSigDB lists | CASTELLANO_NRAS_TARGETS_UP | 64 | 14 | 17758 | 1761 |
SERPINE2,NQO1,PQLC3,USP18,AIM1,TAP1,BAX,KCTD12,IL13RA1,IFIT1,FNDC3A,CRABP2,SDC1,IFIH1 |
| 3.504e-03 | -5.65 | IRE1-mediated unfolded protein response | biological process | GO:0036498 | 56 | 13 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,WIPI1,DNAJC3,WFS1,PDIA5,DNAJB11,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 3.506e-03 | -5.65 | oxidation-reduction process | biological process | GO:0055114 | 1017 | 130 | 16441 | 1675 |
CFAP61,ACACB,GAA,TXN,AASS,CRYM,CPT2,SLC25A13,CACNA2D2,ITPR2,CALM2,CYP1A1,IL6ST,CYP2S1,ALDH1A3,STEAP2,KCNS3,AOX1,AKR1B1,ACOX2,TECR,CYP1B1,PRKAR2B,LOXL2,SLC25A5,IDH1,MRPS36,TP53I3,CYP4F3,POR,KDM4D,SLC25A4,UEVLD,P4HA2,DHTKD1,ADIPOR1,PRKAA2,FAM213B,PPP1R2,ALDH6A1,PYROXD2,SLC25A27,CALM3,NDUFA4,SLC1A3,COX6C,DHRS3,ATP5H,BDH1,PCYOX1,CACNA1D,FAR2,NDUFA12,ALDH3A2,CYP26B1,GFPT1,FADS2,PMPCB,PRODH,OXR1,CALM1,ERO1A,STEAP1,CYB5A,GNAS,PRKAG2,P4HA3,ITPR1,MDH1,FAM213A,XDH,EGLN1,UGP2,NQO1,IQGAP1,P3H2,TMX4,PDIA5,FTH1,MGST2,PRKACA,AIFM2,CYP39A1,CYP26A1,CYP4F11,VAT1,PHKA2,EGLN3,GPX4,AKT1,CYB5R2,ACO1,HTATIP2,ITPR3,COX20,DNAJC10,DUOX1,ALDH3B1,ALDH5A1,PEX2,TRABD2A,CYP2U1,C1orf43,AIFM3,PINK1,ENO2,BLVRB,OSGIN2,PDIA3,CYB561,SPR,LBR,BAX,ECI2,ABCD1,ALDH7A1,OSGIN1,PGM1,ALDH2,OGDHL,BLVRA,LEPR,PRDX4,ACADSB,PLOD2,DHRS2,NR4A3,PGM2L1,PLOD3,CYBRD1 |
| 3.509e-03 | -5.65 | nerve development | biological process | GO:0021675 | 69 | 15 | 16441 | 1675 |
HES1,SERPINE2,CTSV,RET,LRIG1,TFAP2A,ATP8B1,ERBB3,SLC1A3,SEMA3A,HOXB2,DAG1,SIX4,NRP2,SULF2 |
| 3.523e-03 | -5.65 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_UP | 189 | 31 | 17758 | 1761 |
SIRT1,MRC2,SHMT1,NR4A1,FLYWCH2,STAT4,EPHA4,CR2,LYNX1,ITPR2,ZFAND5,PHLDA1,CD83,ATP13A2,SOX13,IRS2,SNTA1,ONECUT1,DACT1,CSF1,FAM63A,AKR1B1,OSTF1,NFKBIZ,ECE1,CITED2,SLC27A3,ACOT7,JARID2,FGD1,CKS2 |
| 3.523e-03 | -5.65 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 189 | 31 | 17758 | 1761 |
CD99,NQO1,VANGL1,GNPDA1,PCBP3,STAT4,HABP4,ERBB2,NRG2,TDRKH,ISYNA1,RAD17,ITPR3,DHRS3,SESN1,DHX32,TOP2A,ENDOD1,DNAJC10,ETS2,STK38,FRYL,AMMECR1,FAM117A,PIK3C2B,MDFIC,PDIA6,HSPB1,MAST4,SCYL3,DOCK9 |
| 3.523e-03 | -5.65 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 189 | 31 | 17758 | 1761 |
PPIF,CASP3,RHOA,NFKBIE,BTNL9,PSME2,DRAP1,LRP4,CTDSPL,SDC4,FURIN,C5orf30,GLO1,PSME1,PTGFRN,GSTP1,SLC25A43,ADRBK2,IER3,MAN2A2,CYP1A1,ZNF823,RALGPS2,UTP14C,DOLPP1,DACT1,CTTN,CMPK2,PDIA6,MCCC2,LAMP3 |
| 3.528e-03 | -5.65 | L-ascorbic acid binding | molecular function | GO:0031418 | 21 | 7 | 16491 | 1673 |
PLOD3,EGLN3,PLOD2,P4HA2,P3H2,P4HA3,EGLN1 |
| 3.530e-03 | -5.65 | TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 51 | 12 | 17758 | 1761 |
IGF1R,ACVRL1,ACVR1C,PTK7,AXL,RYK,TGFBR1,ROR1,ERBB3,DDR1,MERTK,NRP2 |
| 3.530e-03 | -5.65 | MORI_PLASMA_CELL_UP | MSigDB lists | MORI_PLASMA_CELL_UP | 51 | 12 | 17758 | 1761 |
ARMCX3,DDOST,SLC44A1,RRBP1,HTATIP2,MANF,NANS,SPCS3,LMAN1,FAM46C,DNAJB9,M6PR |
| 3.530e-03 | -5.65 | MODULE_85 | MSigDB lists | MODULE_85 | 51 | 12 | 17758 | 1761 |
FGFR2,PTK7,AXL,EPHA4,RYK,ERBB2,TGFBR1,IL13RA1,ROR1,EPHB4,MERTK,LEPR |
| 3.533e-03 | -5.65 | ANATOMICAL_STRUCTURE_DEVELOPMENT | MSigDB lists | ANATOMICAL_STRUCTURE_DEVELOPMENT | 990 | 124 | 17758 | 1761 |
GAA,MTM1,UGT8,NF2,PAPSS2,SSH1,RET,ERBB2,COL18A1,IL18,MRAS,DNER,IER3,CTGF,ARTN,SHC3,DPYSL2,LMO4,IL31RA,LHX6,PAPSS1,DLG1,TWIST1,EPHB4,NOTCH3,RCAN3,F2R,DVL2,SEMA3B,SGCE,MBP,UTRN,NFE2L1,HTATIP2,ZBTB7B,COL12A1,DPYSL3,MDK,DUOX1,ALDH5A1,KCNMB4,SHROOM3,LIMK1,WFS1,SECTM1,BMP1,TLE1,SERPINI1,TMOD2,EFNA5,ARF6,NRGN,HOXC13,NR2C2,FGD1,MAPK12,GCLM,RUNX2,ARAP3,CIT,PBX3,AES,NCKAP1,CRABP2,ETS1,GSTP1,HPCAL4,FGF19,NRP2,ELF3,HDAC9,SCML1,FOXP2,ADORA1,PTEN,CYR61,BAX,TFAP2A,CD9,OSTF1,CITED2,SGCB,MYLIP,ETV7,SPRY2,ALDH3A2,SYK,CCDC88A,SOCS5,FARP2,DPYSL5,HES1,PDGFC,PCDH1,KLK5,GCLC,GYLTL1B,STMN3,COL7A1,NPHP3,RASA1,CDK5R1,SOX13,PITX2,ETS2,ACVRL1,TIMM8A,COL13A1,SCG2,CSF1,ITGA7,ALPK3,FGD6,ERAP1,EGFL7,KLK7,HOXB13,GDF11,SOX8,DRP2,FZD5,SHROOM2,L1CAM,JARID2 |
| 3.550e-03 | -5.64 | LIM_MAMMARY_LUMINAL_MATURE_UP | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_UP | 106 | 20 | 17758 | 1761 |
PVRL4,SORT1,HDAC11,IL13RA1,SLC7A2,TP53INP2,ALCAM,HOXB2,CCDC92,ALDH3B1,MLPH,FAAH,FAM63A,DUSP10,TUBG1,TSPAN13,TSPAN1,SULT2B1,SLC16A5,PROM2 |
| 3.562e-03 | -5.64 | regulation of anatomical structure size | biological process | GO:0090066 | 383 | 56 | 16441 | 1675 |
SEMA6B,GCLM,SSH1,ADD1,EPS8,RET,ARFGEF1,PLXNA1,CRABP2,SPTB,HTR1D,ADORA1,PTEN,MEGF8,DPYSL2,KCNN4,DLG1,PRKG1,TNFRSF12A,SEMA3G,CTTN,IQGAP3,WNT3A,SLC12A2,NEB,SEMA3B,CLCN3,SSH3,RAB3B,RHOA,AKT1,FMN1,GCLC,ANO6,EZR,BBS2,CDK5R1,RASA1,EDNRA,SWAP70,PLEKHH2,SEMA4D,LIMK1,TRIOBP,EFNA5,SPTBN5,NRG1,TMOD2,ARPC2,ARF6,PLOD3,SHROOM2,F2RL1,SEMA3A,RARG,L1CAM |
| 3.562e-03 | -5.64 | human chr1q21 | chromosome location | human chr1q21 | 78 | 13 | 26250 | 1887 |
PIAS3,PSMB4,ARHGEF11,S100A11,BCL9,S100A4,S100A5,TDRKH,ANXA9,RFX5,S100A2,S100A13,S100A6 |
| 3.565e-03 | -5.64 | regulation of binding | biological process | GO:0051098 | 262 | 41 | 16441 | 1675 |
CTHRC1,TXN,NKX3-1,ADD1,HJURP,HABP4,TGFBR1,AES,PRKACA,PDGFB,CTNNBIP1,TFAP4,APLP2,SP100,NEK2,BAX,ADAM15,TMBIM6,SORL1,DAB2IP,TWIST1,IFIT1,WNT3A,MDFI,ZNF462,PLK1,EPB41L5,HES1,RAPGEF2,PLAUR,AMFR,PPARA,NFIB,KDM4D,PTPRF,PLK2,NFKBIA,AURKA,ARRB1,NRG1,TMEM173 |
| 3.570e-03 | -5.64 | BACE1 (beta-site APP-cleaving enzyme 1) | protein interactions | 23621 | 25 | 8 | 16036 | 1726 |
PLSCR1,GGA1,FBXO2,FURIN,BRI3,PDIA3,ATP1B1,RANBP9 |
| 3.572e-03 | -5.63 | soft_tissue-blood_vessel-haemangioma-spindle_cell | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-spindle_cell | 4 | 3 | 17775 | 1757 |
GNAS,IDH1,PIK3CA |
| 3.572e-03 | -5.63 | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | 4 | 3 | 17775 | 1757 |
CDKN2C,IDH1,PTEN |
| 3.572e-03 | -5.63 | meninges-meningioma-rhabdoid | COSMIC cancer mutations | meninges-meningioma-rhabdoid | 4 | 3 | 17775 | 1757 |
NF2,AKT1,IDH1 |
| 3.572e-03 | -5.63 | normal-like_carcinoma | COSMIC cancer mutations | normal-like_carcinoma | 4 | 3 | 17775 | 1757 |
CDH1,PIK3CA,TP53 |
| 3.572e-03 | -5.63 | breast-carcinoma-normal-like_carcinoma | COSMIC cancer mutations | breast-carcinoma-normal-like_carcinoma | 4 | 3 | 17775 | 1757 |
CDH1,PIK3CA,TP53 |
| 3.572e-03 | -5.63 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | 197 | 32 | 17758 | 1761 |
CTSZ,MGST2,CAMK1D,TRIB2,LGALS3BP,RABGGTA,EPCAM,ADD3,GNB5,FUT8,CD9,RFX5,IFIT1,EGLN3,MED30,GM2A,ALDH2,LONRF3,FOS,PTGFRN,ATP10D,CASP4,GABARAPL1,AMZ2,PLCG1,PLK2,CDCA5,IRF7,NRGN,AHR,ABCG1,XDH |
| 3.574e-03 | -5.63 | Kaposi_sarcoma | COSMIC cancer mutations | Kaposi_sarcoma | 27 | 8 | 17775 | 1757 |
PLCG1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 3.574e-03 | -5.63 | soft_tissue-blood_vessel-Kaposi_sarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-Kaposi_sarcoma | 27 | 8 | 17775 | 1757 |
PLCG1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 3.574e-03 | -5.63 | acinar_adenocarcinoma | COSMIC cancer mutations | acinar_adenocarcinoma | 27 | 8 | 17775 | 1757 |
KIF5B,AKT1,FGFR2,PTEN,SDC4,PIK3CA,TP53,ERBB2 |
| 3.580e-03 | -5.63 | STIM2 (stromal interaction molecule 2) | protein interactions | 57620 | 7 | 4 | 16036 | 1726 |
PRKAA2,STIM1,CALM1,HEXB |
| 3.580e-03 | -5.63 | BACE2 (beta-site APP-cleaving enzyme 2) | protein interactions | 25825 | 7 | 4 | 16036 | 1726 |
ATP1B3,GGA1,HLA-E,TMEM30A |
| 3.605e-03 | -5.63 | AMOP_dom | interpro domains | IPR005533 | 4 | 3 | 18293 | 1814 |
SUSD2,MUC4,ISM1 |
| 3.605e-03 | -5.63 | POLO_box_duplicated_dom | interpro domains | IPR000959 | 4 | 3 | 18293 | 1814 |
PLK1,PLK2,PLK4 |
| 3.606e-03 | -5.63 | chr16p | MSigDB lists | chr16p | 4 | 3 | 17758 | 1761 |
PLK1,NUBP1,CRYM |
| 3.609e-03 | -5.62 | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 205 | 33 | 17758 | 1761 |
CTHRC1,SCN5A,SERPINE2,NUAK1,ZCCHC24,HEXB,MRAS,SLC1A3,TMPRSS4,SYTL2,PDIA4,NOV,BHLHE41,DRAM1,RPN2,TSPAN1,CKAP4,DLGAP1,PDGFC,TIMP2,PRICKLE1,ITPR3,ANTXR1,NFIX,SOCS3,RPL12,AXL,PLK2,PGM2L1,NFKBIZ,FHL1,PLOD3,OCLN |
| 3.613e-03 | -5.62 | STK33_DN | MSigDB lists | STK33_DN | 261 | 40 | 17758 | 1761 |
MFSD3,ANXA3,CAST,GALNT12,RET,PM20D2,KBTBD11,CA8,FAM46C,BEX2,NEO1,C16orf74,SPIN4,MGAT4A,AIM1,PCYOX1,TMEM143,ZDHHC23,ACOX2,C12orf75,RASGRP1,LAMP3,OGDHL,CDA,CR2,PRKAR2B,ALCAM,FANCE,SPNS3,CYP4F3,ARHGEF26,ENDOD1,PLCH1,MATN2,PPM1H,KLF5,TANC2,NDFIP1,CXorf56,NXT2 |
| 3.614e-03 | -5.62 | KCNIP3 (Kv channel interacting protein 3, calsenilin) | protein interactions | 30818 | 20 | 7 | 16036 | 1726 |
CALM2,CASP3,KCNIP3,GRK6,IGF1R,ADRBK1,IL6ST |
| 3.614e-03 | -5.62 | CYHR1 (cysteine/histidine-rich 1) | protein interactions | 50626 | 20 | 7 | 16036 | 1726 |
EPN3,LGALS3,DNM1L,DNAJB2,NMI,VPS26A,H1FX |
| 3.617e-03 | -5.62 | OSMAN_BLADDER_CANCER_UP | MSigDB lists | OSMAN_BLADDER_CANCER_UP | 385 | 55 | 17758 | 1761 |
PLA2G4A,GCLM,GOLIM4,SSH1,LGALS3,IL15,IQGAP1,RASA2,SLC25A13,PDIA3,KCTD12,TGOLN2,LACTB2,TIPRL,H1FX,SLC25A36,SPIN4,CTSC,SLC16A6,ALG13,SLC44A1,BAX,SNX16,CITED2,CRTAP,CYP1B1,TRAK2,ENPP4,ACBD5,ALDH2,RIPK2,PLSCR1,LONRF3,SNTB2,LPGAT1,OXR1,PIK3R1,PARP4,CBX6,FBXO9,DIAPH2,FAM133B,RUNX3,DNAJB14,ADRBK2,G2E3,FRMD4B,SCARB2,TAPBP,ALDH3B1,PRPS2,ERAP1,NFKBIZ,TOB1,NXT2 |
| 3.624e-03 | -5.62 | MODULE_154 | MSigDB lists | MODULE_154 | 71 | 15 | 17758 | 1761 |
KLK10,KLK5,LMTK3,CA2,KLHL13,FXYD3,ITGA6,ALDH1A3,CDH3,COL7A1,PPP1R14C,F2RL1,S100A2,EFNB1,CYP26A1 |
| 3.624e-03 | -5.62 | ROSS_AML_WITH_PML_RARA_FUSION | MSigDB lists | ROSS_AML_WITH_PML_RARA_FUSION | 71 | 15 | 17758 | 1761 |
RCN1,PRODH,MRC2,CDKN1C,GALNS,TMX4,ARFGEF1,TLE1,CLMN,IGFBP2,MANF,ITPR2,SLC25A38,ALCAM,GCNT1 |
| 3.624e-03 | -5.62 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 71 | 15 | 17758 | 1761 |
LMO7,RAB3B,LGR4,COL13A1,PLOD2,PLAUR,C3orf52,LOXL2,EPHA1,TSPAN1,F2RL1,S100A2,STEAP1,PTGES,PARM1 |
| 3.624e-03 | -5.62 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | 71 | 15 | 17758 | 1761 |
HLA-B,PSMD1,MRC2,SEC61B,PSMB4,PSME2,HLA-F,TAP1,PDIA3,PSMD10,PSME1,HLA-C,ITGAV,PSMA4,HLA-A |
| 3.624e-03 | -5.62 | CAGNYGKNAAA_UNKNOWN | MSigDB lists | CAGNYGKNAAA_UNKNOWN | 71 | 15 | 17758 | 1761 |
PITX2,TGIF1,NR3C1,CACNA2D2,BMP1,FAM117A,PDE4D,SYTL4,TRIB2,TRAM1,ETS1,PRKACA,TNFRSF19,HOXB2,APPBP2 |
| 3.639e-03 | -5.62 | FBXO6 (F-box protein 6) | protein interactions | 26270 | 618 | 88 | 16036 | 1726 |
SUN1,LAMP1,LTBP1,GAA,SLC25A24,UGT8,TCTN2,HSPG2,SLC25A13,HEXB,DNAJB11,COL18A1,PLXNA1,OAT,LTBP3,CHPF,TUBG1,RPN2,ECE1,LGMN,MINPP1,PDIA6,NAGA,CPD,PLK1,ERLEC1,EZR,IGSF8,PTGFRN,SLC25A5,CDK1,ARF4,MAN2A2,PTPRJ,ATP1A1,DDOST,STK38,GLA,LIFR,GRN,MAN2B2,CMAS,MRC2,EFHD2,ASAH1,CTSZ,ADAMTSL4,LGALS3BP,LMNA,KIAA1161,M6PR,GNS,ITGA3,IGF1R,ALPP,CTSC,MEGF8,COL6A1,SORL1,ADAM15,TRIM21,AHCY,HLA-C,NUP85,CRTAP,IGSF3,GUSB,ERO1A,TMEM245,EMC2,GGH,KIF11,TXNDC11,LEPR,PSMA4,FECH,CNTNAP1,CACHD1,PLOD2,PRCP,HNRNPH2,CTSA,SPCS3,ITGAV,PLOD3,SERPINB1,L1CAM,TMEM131 |
| 3.647e-03 | -5.61 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | 27 | 8 | 17758 | 1761 |
CASP3,CDKN1C,TMX4,SAT1,TP53,PDCL,TRIM21,CTH |
| 3.647e-03 | -5.61 | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | 27 | 8 | 17758 | 1761 |
IGF1R,CDKN1C,PTEN,IL6ST,ZFP36,BCL6,NOTCH3,RARG |
| 3.647e-03 | -5.61 | GROSS_ELK3_TARGETS_UP | MSigDB lists | GROSS_ELK3_TARGETS_UP | 27 | 8 | 17758 | 1761 |
CPD,CCND1,TIMP2,CYR61,ARRB1,MYLIP,F2R,ABCG1 |
| 3.647e-03 | -5.61 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | MSigDB lists | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 27 | 8 | 17758 | 1761 |
CALM2,RASGRF1,RPS6KA2,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D |
| 3.647e-03 | -5.61 | TIAN_TNF_SIGNALING_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_VIA_NFKB | 27 | 8 | 17758 | 1761 |
CTGF,NFKBIE,TNIP1,PLK2,ZFP36,NFKBIA,SDC4,CD83 |
| 3.650e-03 | -5.61 | FOSTER_KDM1A_TARGETS_UP | MSigDB lists | FOSTER_KDM1A_TARGETS_UP | 245 | 38 | 17758 | 1761 |
LMO7,KLK10,HOXB7,AASS,RNF182,CNTNAP2,MGST2,SEPP1,LGALS3BP,CPNE2,AIM1,FXYD5,POF1B,CDH3,MDFIC,EPB41L4B,SULT2B1,SYTL3,RBMS2,MX1,NLRP4,GCA,CDA,HTATIP2,PRICKLE1,IDH1,PRX,NIN,DPYSL3,POPDC3,RBM47,MAP2,NAT1,CTSA,PLD1,FHL1,TMEM159,RRAGD |
| 3.653e-03 | -5.61 | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | 45 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 3.653e-03 | -5.61 | alveolar_soft_part_sarcoma | COSMIC cancer mutations | alveolar_soft_part_sarcoma | 45 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 3.659e-03 | -5.61 | V$NKX62_Q2 | MSigDB lists | V$NKX62_Q2 | 229 | 36 | 17758 | 1761 |
CHCHD7,TSC22D3,RAB6A,SLC20A1,ETS1,FGF19,TSPAN7,LTBP3,SCML1,IER3,CDKN2C,AIM1L,ARTN,CALD1,FLRT3,MITF,TMEM143,CLDN4,TWIST1,DIXDC1,WNT3A,BTBD3,MYT1,ETV4,SMARCA2,SERTAD4,ITPR3,NFIX,SMTNL2,STK38,PELI2,ITGA7,ABCB1,PRIMA1,UNC5B,IFIH1 |
| 3.659e-03 | -5.61 | protease binding | molecular function | GO:0002020 | 104 | 20 | 16491 | 1673 |
CASP3,TIMP2,PINK1,MBP,CAST,AMFR,TP53,FURIN,SELL,ADAMTSL4,TYSND1,RAD23A,TIMP3,ITGA3,SERPINA1,STIM1,CST3,SERPINB6,CD70,ITGAV |
| 3.676e-03 | -5.61 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 76 | 16 | 16441 | 1675 |
PLK1,DLGAP5,AKT1,DNAJB2,GCLC,NUB1,PRICKLE1,PSMD10,TRIB2,RNF19B,BCAP31,PTEN,PLK2,AURKA,ESPL1,SOCS5 |
| 3.677e-03 | -5.61 | negative regulation of neuron death | biological process | GO:1901215 | 162 | 28 | 16441 | 1675 |
SIRT1,GCLM,PINK1,RHOA,CPEB4,AKT1,GCLC,OXR1,GRIN1,PPARA,BCL2L1,RASA1,SIX4,OPTN,MDK,BHLHB9,KIF14,AXL,WFS1,PIK3CA,BAX,NR4A3,SORL1,NR4A2,ERBB3,UNC5B,LGMN,F2R |
| 3.688e-03 | -5.60 | V$AP2REP_01 | MSigDB lists | V$AP2REP_01 | 174 | 29 | 17758 | 1761 |
IER5L,NKX3-1,NFKBIE,AMFR,DDIT4L,PANK1,CALM1,CALM3,TEX2,MORF4L2,EPHA1,EFNB1,LTBP3,FANCI,AKIRIN1,CALM2,CYR61,CALD1,ATP5H,RAP2C,BMP1,NRG1,TACSTD2,EFNA5,C1orf43,MAST4,NR3C2,COL16A1,COBL |
| 3.689e-03 | -5.60 | Ndc80 complex | cellular component | GO:0031262 | 4 | 3 | 17570 | 1756 |
NUF2,SPC25,NDC80 |
| 3.697e-03 | -5.60 | PID_BETA_CATENIN_NUC_PATHWAY | MSigDB lists | PID_BETA_CATENIN_NUC_PATHWAY | 78 | 16 | 17758 | 1761 |
SALL4,BCL9,AES,TCF7,CTNNBIP1,CCND1,PITX2,CDH1,CYR61,ZCCHC12,MITF,TLE1,HDAC1,MDFIC,SP5,NCOA2 |
| 3.697e-03 | -5.60 | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | MSigDB lists | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | 78 | 16 | 17758 | 1761 |
MX1,SERPINE2,NUAK1,SDC4,ASAH1,FTH1,NPC2,IER3,FUCA1,PDLIM3,ITGA3,COL6A1,TACSTD2,HLA-C,IFI6,ABCG1 |
| 3.697e-03 | -5.60 | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | 78 | 16 | 17758 | 1761 |
CLCN3,RET,ASAH1,COL4A5,ALCAM,CDS1,CXXC4,TJP3,RBM47,MLPH,IL6ST,ITPR1,ERBB3,RAB27B,MAST4,MCCC2 |
| 3.700e-03 | -5.60 | PDZ | interpro domains | IPR001478 | 151 | 26 | 18293 | 1814 |
LMO7,FRMPD3,ARHGEF11,RAPGEF2,MPP1,SNTB2,SCRIB,MPP5,ERBB2IP,SNTB1,PRX,SNTA1,SIPA1L2,TJP3,PDLIM3,SHROOM3,RGS3,LIMK1,SIPA1L1,DLG1,DLG3,SHROOM2,MAST4,TIAM1,DVL2,RIMS2 |
| 3.702e-03 | -5.60 | negative regulation of JNK cascade | biological process | GO:0046329 | 32 | 9 | 16441 | 1675 |
PINK1,AKT1,DACT1,ITCH,DUSP10,F2RL1,GSTP1,HIPK3,MECOM |
| 3.715e-03 | -5.60 | PYEON_HPV_POSITIVE_TUMORS_UP | MSigDB lists | PYEON_HPV_POSITIVE_TUMORS_UP | 85 | 17 | 17758 | 1761 |
ZMAT1,SMARCA2,BTNL9,NEURL1B,BARD1,PDIK1L,PSIP1,IL17RB,CDKN2C,E2F7,NR1D2,ZNF367,DONSON,RTKN2,PER3,SYK,MPHOSPH9 |
| 3.715e-03 | -5.60 | TIEN_INTESTINE_PROBIOTICS_2HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_2HR_DN | 85 | 17 | 17758 | 1761 |
SEC23A,MMD,RAPGEF2,GGH,PLXNA1,STX3,ZFYVE16,TNS3,ALDH5A1,PRCP,FLRT3,CALD1,PPP4R1,TCEAL4,ARMCX6,E2F8,CKAP4 |
| 3.717e-03 | -5.59 | Joubert syndrome | SMPDB pathways | SMP00582 | 21 | 8 | 978 | 131 |
PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,ERBB2,PIK3CD,PIKFYVE |
| 3.717e-03 | -5.59 | Phosphatidylinositol Phosphate Metabolism | SMPDB pathways | SMP00463 | 21 | 8 | 978 | 131 |
PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,ERBB2,PIK3CD,PIKFYVE |
| 3.743e-03 | -5.59 | NCOR2 (nuclear receptor corepressor 2) | protein interactions | 9612 | 112 | 22 | 16036 | 1726 |
THRB,SIRT1,NFKBIE,AKT1,NR3C1,NR4A1,THRA,PPARA,MYBL2,CBX6,FOS,RANBP9,NCOA3,NFKBIA,BCL6,AURKA,HDAC1,KLF5,NR4A2,HMGA1,RARG,AHR |
| 3.746e-03 | -5.59 | PID_RHOA_PATHWAY | MSigDB lists | PID_RHOA_PATHWAY | 45 | 11 | 17758 | 1761 |
RHOA,PTEN,CYR61,LIMK1,CIT,EZR,CDKN1B,PLD1,PKN1,FOS,MAPK12 |
| 3.746e-03 | -5.59 | SIG_CHEMOTAXIS | MSigDB lists | SIG_CHEMOTAXIS | 45 | 11 | 17758 | 1761 |
PITX2,AKT1,PTEN,ARHGEF11,LIMK1,ITPR1,PIK3R1,PIK3CA,PIK3CD,ITPR2,ITPR3 |
| 3.759e-03 | -5.58 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 312 | 47 | 16491 | 1673 |
ARHGAP11A,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,RALBP1,IQGAP1,ARFGEF1,RGS20,GPSM2,SIPA1L2,ACAP2,LLGL2,RINL,SH3BP1,RGS3,TBCD,FAM13B,RANBP1,DAB2IP,RP2,IQGAP3,ALS2CL,DOCK4,ARAP2,TBC1D8B,RAPGEF2,ARHGDIB,ATP1B1,GRTP1,ABR,RASA1,ARHGAP35,ARHGAP24,DNAJC10,PLEKHG6,ARHGEF19,SIPA1L1,SH3BP4,ARRB1,AGFG2,ATP1B3,RGS14,TBC1D4,RAP1GAP,CPEB2 |
| 3.762e-03 | -5.58 | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | 182 | 30 | 17758 | 1761 |
DDX58,CMAS,PDGFC,ING1,FBLN5,MMD,ZNF395,EPAS1,ERI2,C6orf106,PRKCQ,INTS8,COX6C,SPTLC2,OPTN,ZFYVE16,DNAJC10,PSMD1,ADD3,PPP2R5A,TAF1B,JAK1,STK38,FUT8,TPST1,RPN2,STK39,PIKFYVE,LTA4H,TRAM1 |
| 3.765e-03 | -5.58 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2204 | 254 | 17775 | 1757 |
EXPH5,LTBP1,PPP4R4,LGR4,AASS,VANGL1,SLC25A13,HEBP1,FLYWCH2,RET,ARFGEF1,CACNA2D2,PPFIBP2,NRG2,ITPR2,DNER,TMC1,SH3KBP1,EPDR1,CDKN2C,NKAIN3,SIPA1L2,ANKS6,LRRC6,IQCE,IMPAD1,PAPSS1,ANKFN1,ALDH1A3,DLG1,AOX1,PIK3CA,ATRNL1,TRPC1,NTN4,ANO4,TLN2,MYRIP,BTBD3,MGAT5,ZNF462,MCTP1,ACVR1C,HSPA12A,ROR1,LDB2,PPP1R14C,ICMT,SESN1,ADRBK2,DPYSL3,EDNRA,AHRR,MAN2A2,TRIM9,PLCG1,AGPAT2,KLF12,MAP2,ATP7B,LRIG1,PRDM5,TANC2,UNC5B,GLCCI1,GAB1,RRAGD,FRMD4A,FAM169A,BVES,TBC1D1,UBASH3B,DNAJB2,ZCCHC24,MTL5,CNTNAP2,SLC1A3,FAM81A,PHLPP1,DHRS3,FBLN1,LMNA,TFAP4,DOPEY2,IGF1R,FAM189A1,FRAS1,RUNDC3B,PRKG1,TPST1,SORL1,CADPS2,LIMCH1,MDFIC,OSTF1,ALPK1,CACNA1D,GAD1,DGKG,ALS2CL,MDFI,CHSY3,DPYSL5,HPS3,TBC1D8B,STRADB,HEATR5A,NPHP3,ANTXR1,ANKRD29,NFIB,PLIN5,DHX32,CACHD1,PLEKHH2,PRKAG2,PELI2,TMEM30A,PRPS2,ALPK3,ARPC2,MAP3K5,HOOK1,SEMA3A,IFIH1,EGLN1,PLA2G4A,NCKAP5,GRHL2,TCTN2,NQO1,PAPSS2,IL15,RALBP1,CTDSPL,XYLT1,TP53,CCDC68,TESK2,IL27RA,RNF182,IL13RA1,MGST2,CYP39A1,ZNF385B,KCTD9,CDS1,TTC21B,APLP2,ACAP2,REEP1,CDH3,GOT1,EPB41L4B,ECE1,EGLN3,MYT1,CTH,CKS2,SULF2,MYO5B,DOCK4,TMTC1,ERLEC1,COL6A2,RIPK2,SLC39A8,PTPN9,SEPT6,ACO1,UTRN,ZNF618,DAG1,CMTM7,PTPRJ,SHROOM3,CDK19,STK38,INPP4B,ZNF704,ADAMTS14,TLE1,NRG1,EFNA5,KLF5,NR3C2,NDST3,COBL,CMAS,GOLIM4,CDH22,ARHGEF11,ATP9A,CENPI,LRP4,RASSF7,EPS8,CCNJL,BTN3A1,GABRG2,PBX3,INTS8,DNAH3,PPP2R3A,NRP2,SH2D4A,LGALS3BP,CD109,DIRAS3,ADORA1,SLC27A6,ANKS1B,PTEN,GTF2F2,WWP1,RBMS2,FARP2,PARP9,ADAMTS2,PDGFC,SUN2,ARHGEF28,RHOA,FAM160A1,FMN1,NR3C1,PIK3R1,CXorf57,OGDHL,DIAPH2,MAML2,LRRC1,GRTP1,SNTB1,KIF11,CRISPLD2,SWAP70,ACADSB,PLOD2,TRIM69,RND3,TBX18,AMMECR1,ABCB1,NETO2,PPM1H,ARRB1,GRAMD1C,WDR62,ARSB,ESPL1,DCBLD1,OCLN,JARID2 |
| 3.765e-03 | -5.58 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2204 | 254 | 17775 | 1757 |
EXPH5,LTBP1,PPP4R4,LGR4,AASS,VANGL1,SLC25A13,HEBP1,FLYWCH2,RET,ARFGEF1,CACNA2D2,PPFIBP2,NRG2,ITPR2,DNER,TMC1,SH3KBP1,EPDR1,CDKN2C,NKAIN3,SIPA1L2,ANKS6,LRRC6,IQCE,IMPAD1,PAPSS1,ANKFN1,ALDH1A3,DLG1,AOX1,PIK3CA,ATRNL1,TRPC1,NTN4,ANO4,TLN2,MYRIP,BTBD3,MGAT5,ZNF462,MCTP1,ACVR1C,HSPA12A,ROR1,LDB2,PPP1R14C,ICMT,SESN1,ADRBK2,DPYSL3,EDNRA,AHRR,MAN2A2,TRIM9,PLCG1,AGPAT2,KLF12,MAP2,ATP7B,LRIG1,PRDM5,TANC2,UNC5B,GLCCI1,GAB1,RRAGD,FRMD4A,FAM169A,BVES,TBC1D1,UBASH3B,DNAJB2,ZCCHC24,MTL5,CNTNAP2,SLC1A3,FAM81A,PHLPP1,DHRS3,FBLN1,LMNA,TFAP4,DOPEY2,IGF1R,FAM189A1,FRAS1,RUNDC3B,PRKG1,TPST1,SORL1,CADPS2,LIMCH1,MDFIC,OSTF1,ALPK1,CACNA1D,GAD1,DGKG,ALS2CL,MDFI,CHSY3,DPYSL5,HPS3,TBC1D8B,STRADB,HEATR5A,NPHP3,ANTXR1,ANKRD29,NFIB,PLIN5,DHX32,CACHD1,PLEKHH2,PRKAG2,PELI2,TMEM30A,PRPS2,ALPK3,ARPC2,MAP3K5,HOOK1,SEMA3A,IFIH1,EGLN1,PLA2G4A,NCKAP5,GRHL2,TCTN2,NQO1,PAPSS2,IL15,RALBP1,CTDSPL,XYLT1,TP53,CCDC68,TESK2,IL27RA,RNF182,IL13RA1,MGST2,CYP39A1,ZNF385B,KCTD9,CDS1,TTC21B,APLP2,ACAP2,REEP1,CDH3,GOT1,EPB41L4B,ECE1,EGLN3,MYT1,CTH,CKS2,SULF2,MYO5B,DOCK4,TMTC1,ERLEC1,COL6A2,RIPK2,SLC39A8,PTPN9,SEPT6,ACO1,UTRN,ZNF618,DAG1,CMTM7,PTPRJ,SHROOM3,CDK19,STK38,INPP4B,ZNF704,ADAMTS14,TLE1,NRG1,EFNA5,KLF5,NR3C2,NDST3,COBL,CMAS,GOLIM4,CDH22,ARHGEF11,ATP9A,CENPI,LRP4,RASSF7,EPS8,CCNJL,BTN3A1,GABRG2,PBX3,INTS8,DNAH3,PPP2R3A,NRP2,SH2D4A,LGALS3BP,CD109,DIRAS3,ADORA1,SLC27A6,ANKS1B,PTEN,GTF2F2,WWP1,RBMS2,FARP2,PARP9,ADAMTS2,PDGFC,SUN2,ARHGEF28,RHOA,FAM160A1,FMN1,NR3C1,PIK3R1,CXorf57,OGDHL,DIAPH2,MAML2,LRRC1,GRTP1,SNTB1,KIF11,CRISPLD2,SWAP70,ACADSB,PLOD2,TRIM69,RND3,TBX18,AMMECR1,ABCB1,NETO2,PPM1H,ARRB1,GRAMD1C,WDR62,ARSB,ESPL1,DCBLD1,OCLN,JARID2 |
| 3.783e-03 | -5.58 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1584 | 188 | 17775 | 1757 |
LTBP1,UGT8,SLC25A13,ATP8A1,FHDC1,CACNA2D2,LMCD1,TEX2,ITPR2,DNER,TMC1,SPTB,SH3KBP1,NKAIN3,SIPA1L2,DPYSL2,IQCE,OSBPL3,ANKFN1,IL31RA,SERINC2,ATRNL1,TRPC1,SNX16,RAB20,RP2,MYH14,MYRIP,ZNF462,MCTP1,SNTB2,HSPA12A,NBPF3,ROR1,LDB2,IDH1,SESN1,STK17B,COL12A1,ENPP1,HS6ST1,MAP2,WIPI1,PRDM5,EPB41L4A,TANC2,UNC5B,RRAGD,FRMD4A,GGA1,RASA2,ZCCHC24,CALB2,CNTNAP2,SLC1A3,DHRS3,FBLN1,RAVER2,B4GALNT1,TNS3,DAZAP1,CA2,FRY,FAM189A1,FRAS1,AIM1,PRKG1,CADPS2,LIMCH1,C10orf54,NCAM1,DGKG,MPHOSPH9,FAM69A,EPB41L5,ELK3,KLK5,MFI2,TBC1D8B,MYBL2,BTN3A2,PDE5A,GLT8D2,CYB5A,STX3,BCAR3,XKRX,CACHD1,TJP3,P4HA3,FGD6,CLMN,ALPK3,CABIN1,KLK7,ATP1B3,PER3,SHROOM2,HOOK1,SEMA3A,XDH,PLA2G4A,LMO7,NCKAP5,MTM1,XYLT1,RGS20,TP53,COL18A1,CYP39A1,ZNF385B,ACAP2,ZNF687,ZNF75D,FRYL,RTKN2,RPN2,EPB41L4B,SCN3A,SULF2,MYO5B,RIPK2,COG2,CAPN6,SEPT6,SYNE2,PANK1,UTRN,DOCK5,NIN,IDE,JAK1,SHROOM3,WFS1,INPP4B,NRG1,SPTBN5,EFNA5,SYT13,LTA4H,NR3C2,NDST3,DENND5B,TTC8,BIN1,WASF3,CMAS,SORT1,TSPAN15,ARHGEF11,POC1B,DAP,LRP4,CDCA8,MIER3,TGFBR1,GTF3A,SEPP1,LBR,PPP2R3A,CD109,TMEM87B,ADORA1,ITGB8,RNF128,ANKS1B,CALD1,BMP7,CD9,IGDCC4,DLGAP1,FMN1,SYBU,MBNL3,DIAPH2,MAML2,LRRC1,GRTP1,KIF11,GALNT3,BANK1,C2orf70,SYT7,FAM117A,CMPK2,PTGES,ABCG1,JARID2 |
| 3.783e-03 | -5.58 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1584 | 188 | 17775 | 1757 |
LTBP1,UGT8,SLC25A13,ATP8A1,FHDC1,CACNA2D2,LMCD1,TEX2,ITPR2,DNER,TMC1,SPTB,SH3KBP1,NKAIN3,SIPA1L2,DPYSL2,IQCE,OSBPL3,ANKFN1,IL31RA,SERINC2,ATRNL1,TRPC1,SNX16,RAB20,RP2,MYH14,MYRIP,ZNF462,MCTP1,SNTB2,HSPA12A,NBPF3,ROR1,LDB2,IDH1,SESN1,STK17B,COL12A1,ENPP1,HS6ST1,MAP2,WIPI1,PRDM5,EPB41L4A,TANC2,UNC5B,RRAGD,FRMD4A,GGA1,RASA2,ZCCHC24,CALB2,CNTNAP2,SLC1A3,DHRS3,FBLN1,RAVER2,B4GALNT1,TNS3,DAZAP1,CA2,FRY,FAM189A1,FRAS1,AIM1,PRKG1,CADPS2,LIMCH1,C10orf54,NCAM1,DGKG,MPHOSPH9,FAM69A,EPB41L5,ELK3,KLK5,MFI2,TBC1D8B,MYBL2,BTN3A2,PDE5A,GLT8D2,CYB5A,STX3,BCAR3,XKRX,CACHD1,TJP3,P4HA3,FGD6,CLMN,ALPK3,CABIN1,KLK7,ATP1B3,PER3,SHROOM2,HOOK1,SEMA3A,XDH,PLA2G4A,LMO7,NCKAP5,MTM1,XYLT1,RGS20,TP53,COL18A1,CYP39A1,ZNF385B,ACAP2,ZNF687,ZNF75D,FRYL,RTKN2,RPN2,EPB41L4B,SCN3A,SULF2,MYO5B,RIPK2,COG2,CAPN6,SEPT6,SYNE2,PANK1,UTRN,DOCK5,NIN,IDE,JAK1,SHROOM3,WFS1,INPP4B,NRG1,SPTBN5,EFNA5,SYT13,LTA4H,NR3C2,NDST3,DENND5B,TTC8,BIN1,WASF3,CMAS,SORT1,TSPAN15,ARHGEF11,POC1B,DAP,LRP4,CDCA8,MIER3,TGFBR1,GTF3A,SEPP1,LBR,PPP2R3A,CD109,TMEM87B,ADORA1,ITGB8,RNF128,ANKS1B,CALD1,BMP7,CD9,IGDCC4,DLGAP1,FMN1,SYBU,MBNL3,DIAPH2,MAML2,LRRC1,GRTP1,KIF11,GALNT3,BANK1,C2orf70,SYT7,FAM117A,CMPK2,PTGES,ABCG1,JARID2 |
| 3.784e-03 | -5.58 | regulation of sodium ion transport | biological process | GO:0002028 | 83 | 17 | 16441 | 1675 |
PRSS8,SCN5A,SERPINE2,AKT1,FXYD3,UTRN,PKP2,ATP1B1,NKAIN3,SNTA1,ATP1A1,DLG1,SGK3,SGK1,FXYD5,ATP1B3,CHP1 |
| 3.788e-03 | -5.58 | ETS_DOMAIN_2 | prosite domains | PS00346 | 26 | 8 | 11866 | 1235 |
ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7 |
| 3.789e-03 | -5.58 | cutaneous_T_cell_lymphoma | COSMIC cancer mutations | cutaneous_T_cell_lymphoma | 33 | 9 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 3.789e-03 | -5.58 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | 33 | 9 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 3.799e-03 | -5.57 | CLEC18A (C-type lectin domain family 18, member A) | protein interactions | 348174 | 11 | 5 | 16036 | 1726 |
SCRIB,ADAMTSL4,PPP2R2D,DNAJC3,DNAJB9 |
| 3.799e-03 | -5.57 | TCTN2 (tectonic family member 2) | protein interactions | 79867 | 11 | 5 | 16036 | 1726 |
HLA-C,ATP1B3,FBXO6,HLA-E,LYPD6 |
| 3.820e-03 | -5.57 | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | 190 | 31 | 17758 | 1761 |
CCNI,DYNLRB1,B3GNT2,PARP12,IQGAP1,MGAT4B,PARP4,DHX8,EFHD2,POMGNT1,SPTLC2,RNPEP,CMTM6,SIRPA,DGKE,PLS3,CARHSP1,AP1AR,MSL1,JAK1,GATA2,CTSC,P4HA2,CDCA7L,CD9,CRY2,GDF11,TECR,SLC25A30,HIPK3,SOCS5 |
| 3.820e-03 | -5.57 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | 190 | 31 | 17758 | 1761 |
ZWINT,SORBS1,ENO2,NF2,SERPINE2,IL15,AASS,STAT4,LITAF,PTGER4,EZR,FTH1,IGSF8,OAT,DHRS3,ARF4,M6PR,GABARAPL1,CTNNBIP1,ATP1A1,COQ10A,CORO1C,CD9,HLA-C,GLA,ATP1B3,AHR,JARID2,ABCC1,SOCS5,EHD1 |
| 3.820e-03 | -5.57 | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | 190 | 31 | 17758 | 1761 |
TPRN,KIF20A,GNPDA1,MRPS15,GUSB,LPGAT1,HABP4,FAM134A,ABCG2,TESK2,KLK6,IL18,COL4A5,ANLN,SESN1,STEAP1,LTBP3,DAG1,CDKN2C,FAM111A,ELMO2,NR1D2,RND3,PPP4R1,ARRB1,KLF5,PLD1,IQGAP3,GLCCI1,MED22,MYO5A |
| 3.820e-03 | -5.57 | GSE3982_MAST_CELL_VS_NKCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_DN | 190 | 31 | 17758 | 1761 |
SUN2,SIGIRR,NUAK1,HLA-F,STAT4,SEPT6,SYNE2,PPARA,CACNA2D2,ABCG2,EIF2AK1,IL27RA,BARD1,HDAC9,ARHGAP24,GABRD,DOLPP1,GALNS,TMC5,REEP1,SECTM1,ATRNL1,NRG1,CADPS2,SPTBN5,OAS3,UNC5B,TSPAN1,F2R,ETV4,RUSC1 |
| 3.820e-03 | -5.57 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | 190 | 31 | 17758 | 1761 |
LZTFL1,SEC61B,RUNX2,ATP8A1,ITCH,SEPT6,CUL4B,TEX2,GLO1,NUCB2,IL18R1,PDIA4,MAPKAPK2,KIF5B,RAB15,DCK,DACT1,MGAT4A,RRBP1,SPINT2,OPN3,UBE2J1,ANKRD12,MDFIC,FHL1,SPCS3,LGMN,TMEM14A,TRAM1,TBC1D4,CCDC88A |
| 3.820e-03 | -5.57 | GSE17721_CTRL_VS_POLYIC_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDM_UP | 190 | 31 | 17758 | 1761 |
CCDC109B,CUL4B,PDCL,ABCG2,TESK2,ARHGDIB,KIF13A,PRKRA,NUCB2,ANLN,HDAC6,TP53INP2,DAG1,HTR1D,FAM111A,NUCB1,ENPP1,FAM64A,STIM1,NGFRAP1,KBTBD2,FAM63A,AKR1B1,CTSA,SCN2A,CCNB2,RARG,MYL12B,MYO5A,CPPED1,WBP5 |
| 3.820e-03 | -5.57 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | 190 | 31 | 17758 | 1761 |
GRN,CCNI,MBP,CHCHD7,GNPDA1,ZC3H11A,RALBP1,HEBP1,IQGAP1,CDC20,ACO1,TGFBR1,ERBB2IP,LTBP3,CYP4F3,FRMD4B,PIAS3,ANKRD10,ENPP1,CARHSP1,CDK16,IL6ST,TFAP2A,PNPLA6,ADAM15,ARRB1,MAPK11,CTSA,BUB1,JARID2,GCNT1 |
| 3.821e-03 | -5.57 | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | 159 | 27 | 17758 | 1761 |
ACBD5,CD55,MRC2,ST14,ASB9,OSGIN2,CTSZ,EPHA1,POMGNT1,PPP1R14C,SDC1,NCS1,G2E3,RAD23A,B4GALNT1,EPCAM,GALNT3,ATP1A1,PLEKHH2,GDE1,STK38,ELF5,GLCCI1,HIPK3,NIPA1,SNX30,DENND5B |
| 3.830e-03 | -5.56 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 471 | 65 | 17758 | 1761 |
TRIM2,SLC25A13,EPHA4,NDC80,RGS20,ARFGEF1,PJA2,BARD1,STIL,ZFYVE9,APPBP2,CTGF,FRYL,KIF14,MYBL1,TIPARP,TIAM1,MGAT5,SMARCA2,CENPA,STAU2,LHFPL2,TLE1,NRG1,WASF3,CDK17,FAM169A,NUAK1,EPS8,PBX3,KIF23,RAB6A,PHLPP1,HMGXB4,PPP2R3A,TOP2A,DOPEY2,CYR61,FUT8,GTF2F2,DAPK1,LIMCH1,PIKFYVE,ATP2B1,NCOA2,SOCS5,NR3C1,RAPGEF2,FNDC3A,KIF11,NFIB,RASA1,BCAR3,NCOA3,SWAP70,PHLPP2,RYK,STK39,CENPE,ZMIZ1,AFAP1,MELK,TMEM131,JARID2,KLF7 |
| 3.834e-03 | -5.56 | IVANOVA_HEMATOPOIESIS_MATURE_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_MATURE_CELL | 270 | 41 | 17758 | 1761 |
LAMP1,CMAS,GOLIM4,CCDC109B,ADD1,CPEB4,HEBP1,CAST,ATP8A1,C5orf30,RAB6A,FAM46C,LBR,BMP2K,ATG4A,MARCH8,KLF3,MARCH2,LGMN,GPX4,TRAK2,GCNT1,CPD,LAMP2,PQLC3,NR3C1,MPP1,EIF5A2,HSPA12A,SERTAD3,STRADB,HTATIP2,STK17B,G2E3,ENDOD1,WIPI1,DCK,OTUB2,ADIPOR1,KLF11,SLC25A38 |
| 3.834e-03 | -5.56 | regulation of protein import | biological process | GO:1904589 | 170 | 29 | 16441 | 1675 |
DDX58,SIRT1,TXN,RHOA,NFKBIE,THRA,PIK3R1,LITAF,RAB23,PSMD10,TGFBR1,IL18,PRKCQ,APC2,IL18R1,FZD7,NOV,CDH1,DACT1,BMP7,CABP1,NFKBIA,DAB2IP,MDFIC,WNT3A,TMEM173,PKIA,MDFI,CHP1 |
| 3.834e-03 | -5.56 | positive regulation of cell projection organization | biological process | GO:0031346 | 271 | 42 | 16441 | 1675 |
GRN,FOXO6,SERPINE2,EPHA4,RET,TGFBR1,NCKAP1,CAMK1D,CRABP2,MNS1,EPS8L2,ITGA3,MEGF8,BMP7,DAB2IP,ESPN,TNFRSF12A,WNT3A,PACSIN1,TIAM1,RIMS2,RHOA,RAPGEF2,PRKCQ,DPYSL3,ARHGAP35,GPRC5B,SEMA4D,BHLHB9,TMEM30A,LIMK1,PTK7,CORO1C,NRG1,EFNA5,ITPKA,ARPC2,ARSB,F2RL1,COBL,L1CAM,PROM2 |
| 3.839e-03 | -5.56 | REACTOME_ER_PHAGOSOME_PATHWAY | MSigDB lists | REACTOME_ER_PHAGOSOME_PATHWAY | 58 | 13 | 17758 | 1761 |
HLA-B,PSMD1,SEC61B,PSMB4,PSME2,HLA-F,TAP1,PDIA3,PSMD10,PSME1,HLA-C,PSMA4,HLA-A |
| 3.839e-03 | -5.56 | NAKAMURA_ADIPOGENESIS_EARLY_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_UP | 58 | 13 | 17758 | 1761 |
IRS2,WASF3,ELK3,PRSS23,ZFP36,PIK3R1,FAM198B,PDE4D,NPTXR,LIFR,ABCA1,GM2A,CYBRD1 |
| 3.839e-03 | -5.56 | SANSOM_WNT_PATHWAY_REQUIRE_MYC | MSigDB lists | SANSOM_WNT_PATHWAY_REQUIRE_MYC | 58 | 13 | 17758 | 1761 |
CCNE2,BMP7,NKD1,TP53,BAX,TNFRSF12A,TCF7,IGFBP2,TNFRSF19,TIAM1,SP5,FZD7,FZD6 |
| 3.839e-03 | -5.56 | PID_SHP2_PATHWAY | MSigDB lists | PID_SHP2_PATHWAY | 58 | 13 | 17758 | 1761 |
RHOA,JAK1,IGF1R,LMO4,IL6ST,PIK3R1,PIK3CA,PDGFB,PRKACA,JAK3,GAB1,FRS3,ARHGAP35 |
| 3.842e-03 | -5.56 | hair cycle | biological process | GO:0042633 | 90 | 18 | 16441 | 1675 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,CTSV,DBI,HDAC1,CDH3,HOXC13 |
| 3.842e-03 | -5.56 | molting cycle | biological process | GO:0042303 | 90 | 18 | 16441 | 1675 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,ZDHHC21,GNAS,PDGFA,CD109,FGFR2,CTSV,DBI,HDAC1,CDH3,HOXC13 |
| 3.845e-03 | -5.56 | positive regulation of small GTPase mediated signal transduction | biological process | GO:0051057 | 38 | 10 | 16441 | 1675 |
RASGRF1,ADGRG1,CSF1,ARRB1,ERBB2,NRG1,RASGEF1A,F2R,F2RL1,RASGRP1 |
| 3.853e-03 | -5.56 | ErbB-2 class receptor binding | molecular function | GO:0005176 | 4 | 3 | 16491 | 1673 |
NRG1,ERBB2IP,MUC4 |
| 3.853e-03 | -5.56 | oxoglutarate dehydrogenase (succinyl-transferring) activity | molecular function | GO:0004591 | 4 | 3 | 16491 | 1673 |
DHTKD1,MRPS36,OGDHL |
| 3.853e-03 | -5.56 | beta-adrenergic receptor kinase activity | molecular function | GO:0047696 | 4 | 3 | 16491 | 1673 |
GRK6,ADRBK1,ADRBK2 |
| 3.853e-03 | -5.56 | AP-1 adaptor complex binding | molecular function | GO:0035650 | 4 | 3 | 16491 | 1673 |
AP1AR,RAB38,ARPC2 |
| 3.853e-03 | -5.56 | TAP1 binding | molecular function | GO:0046978 | 4 | 3 | 16491 | 1673 |
TAPBP,HLA-F,TAP1 |
| 3.853e-03 | -5.56 | ErbB-3 class receptor binding | molecular function | GO:0043125 | 4 | 3 | 16491 | 1673 |
ERBB2,NRG1,PIK3R1 |
| 3.866e-03 | -5.56 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 198 | 32 | 17758 | 1761 |
ST14,CD82,TAP1,TP53,SDC1,TNFSF9,EPS8L2,IER3,PDGFA,KIF13B,BAX,DRAM1,WWP1,F2R,PTPRE,ZNF365,OSGIN1,GM2A,DDB2,ADCK3,S100A4,SAT1,SERTAD3,SESN1,RNF19B,FOS,CDK5R1,FAS,FUCA1,PLK2,TOB1,DEF6 |
| 3.873e-03 | -5.55 | GNF2_CD48 | MSigDB lists | GNF2_CD48 | 33 | 9 | 17758 | 1761 |
HLA-B,TAPBP,HLA-E,HLA-F,INPP5D,ARHGDIB,GRK6,HLA-C,HLA-A |
| 3.873e-03 | -5.55 | DOANE_BREAST_CANCER_CLASSES_DN | MSigDB lists | DOANE_BREAST_CANCER_CLASSES_DN | 33 | 9 | 17758 | 1761 |
TIMP2,ARTN,POPDC3,PLOD2,PLAUR,LMO4,PAPSS1,CLIP4,SGCB |
| 3.873e-03 | -5.55 | JIANG_HYPOXIA_VIA_VHL | MSigDB lists | JIANG_HYPOXIA_VIA_VHL | 33 | 9 | 17758 | 1761 |
IRF2BPL,SCARB2,ENO2,KBTBD2,UACA,C6orf106,GTF2A2,CKAP4,WBP5 |
| 3.873e-03 | -5.55 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | MSigDB lists | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 33 | 9 | 17758 | 1761 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D |
| 3.873e-03 | -5.55 | FRIDMAN_IMMORTALIZATION_DN | MSigDB lists | FRIDMAN_IMMORTALIZATION_DN | 33 | 9 | 17758 | 1761 |
CTGF,IGFBP6,ALDH1A3,TP53,HTATIP2,IRF7,AHR,CYP1B1,OPTN |
| 3.873e-03 | -5.55 | Tetraspanin/Peripherin | interpro domains | IPR018499 | 33 | 9 | 18293 | 1814 |
CD63,TSPAN15,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,TSPAN7 |
| 3.879e-03 | -5.55 | PID_RET_PATHWAY | MSigDB lists | PID_RET_PATHWAY | 39 | 10 | 17758 | 1761 |
IRS2,RHOA,DOK4,PIK3R1,RET,PIK3CA,PRKACA,BCAR1,GAB1,RASA1 |
| 3.879e-03 | -5.55 | SPINDLE | MSigDB lists | SPINDLE | 39 | 10 | 17758 | 1761 |
DLGAP5,CDC20,KIF23,TUBG1,AURKA,BUB1,NDE1,KIF11,CDK1,SAC3D1 |
| 3.888e-03 | -5.55 | negative regulation of cell migration | biological process | GO:0030336 | 193 | 32 | 16441 | 1675 |
TCAF1,ARAP3,NF2,ADGRG1,PKP2,VASH1,NOV,SVBP,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,CITED2,CYP1B1,PTPRU,ACVR1C,RGCC,PTGER4,ARHGDIB,EPHA1,DAG1,ABR,DPYSL3,PTPRJ,ACVRL1,CORO1C,RAP2C,NRG1,EGFL7,SEMA3A |
| 3.895e-03 | -5.55 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 303 | 45 | 17758 | 1761 |
EXPH5,MTM1,GNE,TMX4,KIF23,PHLPP1,CCNB1,HMGXB4,APPBP2,SLC25A36,TOP2A,WEE1,FRYL,KIF14,PLK4,KLF9,ERBB3,PIKFYVE,TIPARP,MAST4,BTBD3,NCOA2,ATP2B1,DOCK4,CENPA,NR3C1,GCLC,MICB,RAPGEF2,FNDC3A,KIF11,BCAR3,LRRC42,NCOA3,FGFR2,KBTBD2,SLC9A6,AURKA,MAP3K5,ZMIZ1,CCNB2,AHR,KLF7,JARID2,DOCK9 |
| 3.895e-03 | -5.55 | CCCNNGGGAR_V$OLF1_01 | MSigDB lists | CCCNNGGGAR_V$OLF1_01 | 303 | 45 | 17758 | 1761 |
LASP1,ARMCX3,UPF3B,NF2,CHCHD7,THRA,COL18A1,FAM198B,TRIB2,DDR1,SYTL2,MECOM,NEO1,CA2,RGS3,VASN,VAT1,SEMA3G,EPB41L4B,PACSIN1,ETV4,TIAM1,DPYSL5,PDGFC,TRIM8,PLEKHA6,ELK3,TNIP1,FOXJ2,CBX6,C2orf69,DUSP4,SP4,ABR,EPN3,ATP1A1,H1F0,AXL,SLC9A6,NFKBIA,GRIN2D,ANXA9,NDFIP1,AIFM3,JARID2 |
| 3.901e-03 | -5.55 | negative regulation of Rac protein signal transduction | biological process | GO:0035021 | 4 | 3 | 16441 | 1675 |
STMN3,ARHGAP24,ARAP3 |
| 3.901e-03 | -5.55 | calcium activated phosphatidylserine scrambling | biological process | GO:0061589 | 4 | 3 | 16441 | 1675 |
ANO9,ANO4,ANO6 |
| 3.901e-03 | -5.55 | negative regulation of phospholipid biosynthetic process | biological process | GO:0071072 | 4 | 3 | 16441 | 1675 |
PDGFA,SLC27A1,PDGFB |
| 3.905e-03 | -5.55 | V$FREAC4_01 | MSigDB lists | V$FREAC4_01 | 144 | 25 | 17758 | 1761 |
HSPG2,NR4A1,ROR1,OSR2,CAMK1D,PHLPP1,PPP2R3A,ZNF385B,SCML1,PLS3,PITX2,CD109,FOXP2,FRY,KLF12,CALD1,KBTBD2,LMO4,VASN,PELI2,CITED2,CLIP2,MAST4,BTBD3,RARG |
| 3.906e-03 | -5.55 | SH3_1 | pfam domains | PF00018 | 97 | 19 | 16629 | 1696 |
SORBS1,PACSIN2,TRIP10,EPS8,SPATA13,TEC,YES1,DOCK5,BCAR1,EPS8L2,RASA1,PLCG1,ARHGEF37,PLCG2,DLG1,OSTF1,DLG3,ARHGEF9,ARHGEF4 |
| 3.910e-03 | -5.54 | ODONNELL_TFRC_TARGETS_UP | MSigDB lists | ODONNELL_TFRC_TARGETS_UP | 378 | 54 | 17758 | 1761 |
PRKAA2,BIN1,CASP3,ACACB,LGR4,TSC22D3,NRG2,IL13RA1,FTH1,F11R,FAM46C,KREMEN1,TNFSF9,DAPK2,LLGL2,METTL7A,ZNRF2,CALD1,SGK1,MYH14,PIM1,NCAM1,CITED2,MYLIP,TIAM1,TPCN1,APOBEC3G,SP5,IGSF3,MYO5B,DPYSL5,TRIM8,ALDH2,BTNL9,SAT1,C3orf52,MYEOV,TFAP2C,SESN1,STK17B,NFIB,RHEB,PLIN5,FAS,SERPINA1,TJP3,WIPI1,FGFR2,PLK2,INPP4B,NR4A3,ARRB1,HOXB13,PER3 |
| 3.913e-03 | -5.54 | POLO_box | pfam domains | PF00659 | 4 | 3 | 16629 | 1696 |
PLK1,PLK2,PLK4 |
| 3.915e-03 | -5.54 | V$OCT_Q6 | MSigDB lists | V$OCT_Q6 | 246 | 38 | 17758 | 1761 |
SCOC,THRA,TSC22D3,MRAS,MGAT5B,HPCAL4,PPP2R3A,HDAC9,FOXP2,SESN3,ADORA1,PTEN,CYR61,DPYSL2,LHX6,ATP8B1,CNNM4,TWIST1,TSPAN13,PDE4D,FZD4,SH3BGRL,SERTAD4,STAT4,KIF13A,LDB2,ITPR3,TP53INP2,DPYSL3,CXXC4,GPRC5B,FAM117A,SP6,TMOD2,CEP41,ARF6,TLL2,DIS3L |
| 3.915e-03 | -5.54 | V$LMO2COM_01 | MSigDB lists | V$LMO2COM_01 | 246 | 38 | 17758 | 1761 |
NRG2,CALM3,CAMK1D,CRABP2,PKN1,PDGFB,PSIP1,CYP26A1,CALM2,KIF5B,GATA2,PAQR5,DLG1,BCL6,TSPAN13,ERBB3,ZRANB1,WNT3A,CITED2,MAP3K3,TRIM8,OXR1,CALM1,RGAG1,GRIN1,ATP1B1,RANBP9,COL12A1,GNAS,PTPRJ,IDE,SMTNL2,ITGA7,OSR1,NR3C2,PRR15,RARG,DOCK9 |
| 3.915e-03 | -5.54 | GTACTGT,MIR-101 | MSigDB lists | GTACTGT,MIR-101 | 246 | 38 | 17758 | 1761 |
SPRED1,LRRFIP2,SOX9,ETV5,TGFBR1,POMGNT1,PHLDA1,SIX4,TEAD3,ZNF385B,FZD6,SGPL1,FLRT3,SEMA3G,PDE4D,SLC39A10,MYRIP,BTBD3,SOCS5,THRB,CLCN3,PHF20L1,FZD4,BCL9,UBE2A,ERBB2IP,FOS,DAG1,C3orf58,RANBP9,CDK5R1,MMP15,PLCG1,RAP2C,PIK3C2B,PIEZO1,NDFIP1,CPEB2 |
| 3.920e-03 | -5.54 | PID_PDGFRB_PATHWAY | MSigDB lists | PID_PDGFRB_PATHWAY | 129 | 23 | 17758 | 1761 |
PLA2G4A,DOCK4,RHOA,IQGAP1,EPS8,PIK3R1,YES1,NCKAP1,ELK1,BCAR1,PDGFB,FOS,RASA1,ARHGAP35,PLCG1,PTPRJ,PTEN,PIK3CA,ITGAV,CTTN,PIK3CD,ARPC2,GAB1 |
| 3.949e-03 | -5.53 | PDZ | prosite domains | PS50106 | 145 | 26 | 11866 | 1235 |
LMO7,FRMPD3,ARHGEF11,MPP1,SNTB2,RAPGEF2,MPP5,SCRIB,ERBB2IP,SNTB1,PRX,SNTA1,SIPA1L2,PDLIM3,TJP3,SHROOM3,LIMK1,RGS3,SIPA1L1,DLG1,DLG3,SHROOM2,TIAM1,MAST4,DVL2,RIMS2 |
| 3.964e-03 | -5.53 | positive regulation of cellular component organization | biological process | GO:0051130 | 1056 | 134 | 16441 | 1675 |
ATP8A1,EPHA4,RET,CAMK1D,CCNB1,HDAC6,PDGFB,SDC1,CTGF,SIVA1,MITF,DLG1,CTTN,PACSIN1,TIAM1,PLK1,NBPF3,EZR,ABR,DPYSL3,GPRC5B,DNM1L,LIMK1,NOD2,PIEZO1,ITPKA,ARF6,RAP1GAP,F2RL1,GRN,BMF,SERPINE2,SOX9,NCKAP1,MERTK,ITGA3,IGF1R,GATA2,MEGF8,FLRT3,NEK2,TNFRSF12A,WNT3A,RIMS2,EPB41L5,MFI2,ANO6,PIP4K2C,EPHA1,STX3,CDK5R1,FAS,SEMA4D,TMEM30A,CDCA5,AURKA,ARPC2,COL16A1,EHD1,PROM2,FOXO6,SORBS1,DLGAP5,NF2,TP53,ERBB2,MNS1,EPS8L2,ARHGEF16,PLCG2,PLK4,BCL6,CDKN1B,TWIST1,ESPN,DAB2IP,TSPAN1,LMAN1,CHP1,SIRT1,PPIF,AKT1,CDC20,NUSAP1,PRKCQ,DAG1,ARHGAP35,IDE,PTPRJ,BHLHB9,AXL,PTK7,CORO1C,TRIOBP,NRG1,EFNA5,COBL,TCAF1,PINK1,CD63,SDC4,LRP4,GDF15,TGFBR1,CRABP2,SRPX2,ADGRB2,KIF5B,PTEN,BMP7,FAM20B,BAX,GTF2F2,CNOT6L,SYK,HES1,RHOA,FMN1,PLAUR,RAPGEF2,EIF5A2,PIK3R1,RGCC,SWAP70,ARRB1,GPER1,ITGAV,FZD5,ARSB,UBE2C,L1CAM,AHR,ESPL1,JARID2 |
| 3.969e-03 | -5.53 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 107 | 20 | 17758 | 1761 |
REC8,CD55,CDKN1C,NR3C1,DNAJB2,SLC39A8,FAM134A,FTH1,TP53I3,BMP2K,HOXA9,SECTM1,CCDC69,SGK1,TWIST1,CTSA,CITED2,GAD1,CYP1B1,LAMP3 |
| 3.975e-03 | -5.53 | functioning | COSMIC cancer mutations | functioning | 1876 | 219 | 17775 | 1757 |
EXPH5,HECA,PPP4R4,KIAA1462,VANGL1,ATP8A1,EPHA4,RET,ARFGEF1,NRG2,MPP5,CA8,ERP29,SPTB,GRM5,SIPA1L2,PQLC2,STIM1,RGS3,MKRN3,TSPAN6,IL31RA,STEAP2,ABCA2,POF1B,SNX16,MYH14,TLN2,ARMCX6,TIAM1,MYRIP,BTBD3,TIPARP,NEB,ERAP2,SMARCA2,TRIM8,MCTP1,KIFC2,CELSR2,SNTB2,ITCH,KLK6,F12,PTGFRN,COL12A1,AHRR,PLEKHG6,SLC25A4,HPSE,PTER,GNPTAB,MADD,NOD2,ADIPOR1,SP6,EPB41L4A,RRAGD,ARAP3,FRMD4A,HJURP,LGALS3,ITGA6,ETV5,CALB2,SAMD9,NCKAP1,TTYH3,TNS3,AIM1L,FRY,SNX18,FRAS1,KIF13B,MEGF8,CADPS2,ALPK1,PIKFYVE,WNT3A,MYLIP,PLCB2,DGKG,GPR161,KLK5,PCDH1,MICB,EIF2AK1,RNF113A,HEATR5A,TP53INP2,PRX,MUM1L1,STK17A,NCOA3,AP1AR,ETS2,MATN2,FAM83D,FGD6,CABIN1,GDF11,ZDBF2,DRP2,SHROOM2,SERPINB1,ADAMTS16,NCKAP5,FOXM1,ACTR8,BROX,IQGAP1,CCDC110,TP53,CCDC68,PKP2,SYTL2,APPBP2,SS18,MUC16,ZNF687,ST5,ARTN,SETDB2,XYLT2,FRYL,FABP6,LHX6,DAB2IP,RPN2,GOT1,TMEM64,ARL4D,RAB27B,RASGEF1A,PDIA6,SCN3A,SULF2,DOCK4,TMTC1,COG2,CAPN6,SYNE2,ACO1,UTRN,PRKCQ,ERBB2IP,ALCAM,FANCE,ATP10D,ARHGAP35,NIN,DDOST,RBL1,INPP4B,PNPLA6,TLE1,SPTBN5,RGS14,NDST3,BIN1,ANXA3,ARHGEF3,SORT1,NKX3-1,ARHGEF11,MACC1,ATP9A,ESRP1,GTF3A,TRMT2B,DNAH3,HMGXB4,SLC9A2,NRP2,PDIA4,SNTA1,TOP2A,CARD8,LYPD6,BMP7,TOX2,GALNS,KIAA0319,CD9,ATP8B1,TRIM21,ABCD1,IQGAP3,SLC16A5,NCOA2,MYO5A,ATP2B1,PVRL4,HMMR,ADAMTS2,PDGFC,ARHGEF28,PSMB4,FMN1,NR4A1,GRIN1,CXorf57,PARP4,FURIN,MAML2,COL7A1,FNDC3A,TXNDC11,NUCB1,UACA,PGM2L1,ZMIZ1,L1CAM,OCLN,ARHGEF4,TLL2,JARID2,ESYT2,GOLGB1 |
| 3.975e-03 | -5.53 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1876 | 219 | 17775 | 1757 |
EXPH5,HECA,PPP4R4,KIAA1462,VANGL1,ATP8A1,EPHA4,RET,ARFGEF1,NRG2,MPP5,CA8,ERP29,SPTB,GRM5,SIPA1L2,PQLC2,STIM1,RGS3,MKRN3,TSPAN6,IL31RA,STEAP2,ABCA2,POF1B,SNX16,MYH14,TLN2,ARMCX6,TIAM1,MYRIP,BTBD3,TIPARP,NEB,ERAP2,SMARCA2,TRIM8,MCTP1,KIFC2,CELSR2,SNTB2,ITCH,KLK6,F12,PTGFRN,COL12A1,AHRR,PLEKHG6,SLC25A4,HPSE,PTER,GNPTAB,MADD,NOD2,ADIPOR1,SP6,EPB41L4A,RRAGD,ARAP3,FRMD4A,HJURP,LGALS3,ITGA6,ETV5,CALB2,SAMD9,NCKAP1,TTYH3,TNS3,AIM1L,FRY,SNX18,FRAS1,KIF13B,MEGF8,CADPS2,ALPK1,PIKFYVE,WNT3A,MYLIP,PLCB2,DGKG,GPR161,KLK5,PCDH1,MICB,EIF2AK1,RNF113A,HEATR5A,TP53INP2,PRX,MUM1L1,STK17A,NCOA3,AP1AR,ETS2,MATN2,FAM83D,FGD6,CABIN1,GDF11,ZDBF2,DRP2,SHROOM2,SERPINB1,ADAMTS16,NCKAP5,FOXM1,ACTR8,BROX,IQGAP1,CCDC110,TP53,CCDC68,PKP2,SYTL2,APPBP2,SS18,MUC16,ZNF687,ST5,ARTN,SETDB2,XYLT2,FRYL,FABP6,LHX6,DAB2IP,RPN2,GOT1,TMEM64,ARL4D,RAB27B,RASGEF1A,PDIA6,SCN3A,SULF2,DOCK4,TMTC1,COG2,CAPN6,SYNE2,ACO1,UTRN,PRKCQ,ERBB2IP,ALCAM,FANCE,ATP10D,ARHGAP35,NIN,DDOST,RBL1,INPP4B,PNPLA6,TLE1,SPTBN5,RGS14,NDST3,BIN1,ANXA3,ARHGEF3,SORT1,NKX3-1,ARHGEF11,MACC1,ATP9A,ESRP1,GTF3A,TRMT2B,DNAH3,HMGXB4,SLC9A2,NRP2,PDIA4,SNTA1,TOP2A,CARD8,LYPD6,BMP7,TOX2,GALNS,KIAA0319,CD9,ATP8B1,TRIM21,ABCD1,IQGAP3,SLC16A5,NCOA2,MYO5A,ATP2B1,PVRL4,HMMR,ADAMTS2,PDGFC,ARHGEF28,PSMB4,FMN1,NR4A1,GRIN1,CXorf57,PARP4,FURIN,MAML2,COL7A1,FNDC3A,TXNDC11,NUCB1,UACA,PGM2L1,ZMIZ1,L1CAM,OCLN,ARHGEF4,TLL2,JARID2,ESYT2,GOLGB1 |
| 3.986e-03 | -5.53 | ear development | biological process | GO:0043583 | 201 | 33 | 16441 | 1675 |
CTHRC1,SOX9,SDC4,SLC25A27,OSR2,PLPPR4,TMC1,SIX4,FZD6,PLS3,GATA2,ALDH1A3,TFAP2A,CDKN1B,ATP8B1,TWIST1,ECE1,WNT3A,SPRY2,DVL2,HES1,SCRIB,PRKRA,ABR,MAPKAPK2,FAT4,FGFR2,PTK7,TBX18,LRIG1,NR4A3,OSR1,SHROOM2 |
| 3.990e-03 | -5.52 | MODULE_69 | MSigDB lists | MODULE_69 | 489 | 67 | 17758 | 1761 |
LMO7,AASS,MRPS15,TSC22D3,TP53,NDRG2,NANS,BARD1,CMTM6,TYMP,RNF220,CYP1A1,ESPN,PDE4D,SCARA3,ATG4D,SNTB2,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,KDM4D,AMZ2,ENPP1,NEIL1,SLC9A6,PLEKHG1,PCSK5,RRAGD,LMTK3,CDH22,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,TFAP4,C9orf69,RALGPS2,CDK16,UBE2J1,CD9,FAR2,CITED2,PIKFYVE,ABCC1,AMOTL2,ADCK3,FMN1,TBC1D8B,MICB,FURIN,MYBL2,PIP4K2C,DIAPH2,FOS,BSDC1,PTPRF,GALNT3,FGFR2,CSF1,S100A5,FGD6,TMEM120A,PKIA,EGLN1 |
| 3.991e-03 | -5.52 | caveola | cellular component | GO:0005901 | 78 | 16 | 17570 | 1756 |
SPRED1,SCN5A,PACSIN2,LRP4,ATP1B1,HDAC6,EMP2,ATP1A1,CDH1,IGF1R,CORO1C,PRKCDBP,EFNA5,SLC27A1,ATP1B3,F2R |
| 4.004e-03 | -5.52 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | 1359 | 164 | 17758 | 1761 |
CCNI,CASP3,TXN,HSPG2,MRPS15,HEBP1,CNOT8,CUL4B,F11R,ITPR2,MORF4L2,OAT,HDAC6,PSMD1,PAPSS1,RP2,METAP2,SMARCA2,CD55,SH3BGRL,STAU2,PRKAR2B,SAV1,PRKRA,ICMT,TP53I3,ARF4,MAN2A2,GDE1,DNM1L,ATP7B,HOXA9,CAB39,HDAC1,F2RL1,LRRFIP2,SERPINE2,ALDH6A1,PEX6,ISYNA1,PSIP1,LMNA,GNS,B3GALNT1,DAZAP1,GATA2,KCNN4,RANBP1,PPP4R1,DAPK1,PIM1,MCCC2,ABCC1,TRAK2,FADS2,PMPCB,STAT4,MGAT4B,HMG20B,EIF2AK1,PCTP,PSMA4,RANBP9,RASA1,FAS,FECH,SCARB2,SLCO4A1,ETS2,SEMA4D,CSF1,MATN2,PITPNA,MDH1,GDF11,MAP3K5,EHD1,CEP70,UPF3B,UGP2,CAST,CD82,RALBP1,MGST2,BCL2L1,SS18,CDH1,WDR44,LMO4,RPN2,ACSL4,MINPP1,LMAN1,F2R,GM2A,CTH,SEPHS1,CPD,SIRT1,AKT1,DRAP1,SLC39A8,ACO1,GLO1,PRKCQ,RAB38,ERBB2IP,RAD17,GTF2A2,H2AFV,DAG1,FZD7,IDE,ATP1A1,ALDH5A1,PPP2R5A,NGFRAP1,CORO1C,SLC9A6,PEX2,INPP4B,GCLM,NUDT6,CMAS,PACSIN2,ARHGEF3,CD63,BLVRB,PSMD10,PBX3,LBR,VPS26A,MDM1,ECI2,TAGLN2,CITED2,S100A6,WBP5,PDGFC,SHMT1,B3GNT2,PLSCR1,GCLC,RAPGEF2,MPP1,GGH,YES1,LEPR,PRDX4,DCTN6,TWSG1,PLOD2,HNRNPH2,AMMECR1,NMI,RAP2C,SPINT2,PGRMC1,RYK,ARRB1,FAM117A,NDFIP1,AHR,ACOT7 |
| 4.008e-03 | -5.52 | ALDEHYDE_DEHYDR_GLU | prosite domains | PS00687 | 16 | 6 | 11866 | 1235 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH3A2,ALDH1A3 |
| 4.008e-03 | -5.52 | ALDEHYDE_DEHYDR_CYS | prosite domains | PS00070 | 16 | 6 | 11866 | 1235 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 4.011e-03 | -5.52 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | 320 | 47 | 17758 | 1761 |
BIN1,PAPSS2,ADD1,DLGAP5,INPP5D,RASA2,CUL4B,LMCD1,GDF15,HES2,B4GALT4,IL18R1,RAD23A,IER3,CXCL16,PTEN,ALG13,SLC44A1,CST3,SGK3,BAX,BCL6,SORL1,FAIM,PPP6R1,CTH,PPIF,PLK1,THRB,MBP,ZWINT,TESK1,NR3C1,LITAF,CCDC34,ARFRP1,CMTM7,PRKAG2,PPP2R5A,GDE1,NMI,TRIOBP,ARF6,NDFIP1,ST3GAL1,LIFR,ABCA1 |
| 4.018e-03 | -5.52 | IRE1alpha activates chaperones | REACTOME pathways | R-HSA-381070 | 55 | 13 | 8202 | 867 |
GFPT1,SEC61B,ADD1,WIPI1,WFS1,DNAJC3,PDIA5,DNAJB11,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 4.018e-03 | -5.52 | Arachidonic acid metabolism | REACTOME pathways | R-HSA-2142753 | 55 | 13 | 8202 | 867 |
MAPKAPK2,PLA2G4A,FAM213B,CYP1A1,CYP4F11,FAAH,CYP2U1,LTA4H,PTGES,CYP4F3,ABCC1,CYP1B1,GPX4 |
| 4.022e-03 | -5.52 | Doxorubicin Metabolism Pathway | SMPDB pathways | SMP00650 | 17 | 7 | 978 | 131 |
NQO1,POR,RALBP1,XDH,ABCB1,ABCC1,ABCG2 |
| 4.028e-03 | -5.51 | Post NMDA receptor activation events | REACTOME pathways | R-HSA-438064 | 37 | 10 | 8202 | 867 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,PRKACA |
| 4.037e-03 | -5.51 | SAM_PNT | smart domains | SM00251 | 11 | 5 | 9131 | 997 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 4.046e-03 | -5.51 | PID_HIF1_TFPATHWAY | MSigDB lists | PID_HIF1_TFPATHWAY | 65 | 14 | 17758 | 1761 |
FECH,PGM1,AKT1,GATA2,BHLHE41,FURIN,ABCG2,ABCB1,EGLN3,CITED2,ETS1,FOS,NCOA2,EGLN1 |
| 4.046e-03 | -5.51 | MORF_BUB1B | MSigDB lists | MORF_BUB1B | 65 | 14 | 17758 | 1761 |
HMMR,TOP2A,PLK1,CDKN2C,ZWINT,CENPA,KIF14,NDC80,PLK4,BUB1,GTF2A2,CDK1,NAGA,ESPL1 |
| 4.049e-03 | -5.51 | Insulin resistance | KEGG pathways | hsa04931 | 111 | 22 | 6908 | 758 |
PRKAA2,GFPT1,ACACB,SLC2A4,AKT1,RPS6KA1,PIK3R1,PPARA,PRKCQ,SOCS3,PTPRF,IRS2,RPS6KA2,PRKAG2,SLC27A6,PTEN,NFKBIA,PIK3CA,SLC27A1,PIK3CD,SLC27A3,TBC1D4 |
| 4.050e-03 | -5.51 | MAPK10 (mitogen-activated protein kinase 10) | protein interactions | 5602 | 48 | 12 | 16036 | 1726 |
CDKN2C,TNIP1,TP53,EZR,DUSP10,ARRB1,CDKN1B,HDAC1,PKMYT1,ELK1,WDR62,HDAC9 |
| 4.050e-03 | -5.51 | ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) | protein interactions | 6093 | 48 | 12 | 16036 | 1726 |
ARHGAP24,CASP3,MBP,RHOA,ADD1,PTEN,RND3,DPYSL2,LIMK1,ARRB1,EZR,GAB1 |
| 4.052e-03 | -5.51 | ion homeostasis | biological process | GO:0050801 | 578 | 79 | 16441 | 1675 |
CCDC109B,EPAS1,ATP2C2,HEXB,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,SLC9A7,ATP6V0B,APLP2,PQLC2,SCNN1A,PLCG2,STEAP2,TRPC1,CNNM4,GOT1,RAB20,TMEM64,SLC39A10,F2R,CHP1,SIRT1,CLCN3,CD55,ACO1,SLC11A2,ATP1B1,RAB38,CD40,ITPR3,EDNRA,ATP13A2,ENPP1,ATP1A1,WFS1,SLC9A6,ATP7B,INPP4B,F2RL1,ABCA1,PRKAA2,CALB2,MTL5,SLC25A27,ABCG2,SLC9A2,NEO1,CA2,GATA2,BAX,SGK3,SGK1,TMBIM6,SLC12A2,ATP2B1,SLC37A1,MFI2,ERO1A,GRIN1,TTC7A,EIF2AK1,NUBP1,SFXN5,STEAP1,FECH,SWAP70,SLC4A4,ITPR1,SLC4A3,ATP1B3,MCUR1,GPER1,NDFIP1,JAK3,CYBRD1,ABCG1 |
| 4.060e-03 | -5.51 | spindle pole | cellular component | GO:0000922 | 121 | 22 | 17570 | 1756 |
PLK1,DLGAP5,CKAP2,ASPM,POC1B,CALM1,CDC20,CALM3,CCNB1,KIF11,NIN,CALM2,PLEKHG6,FRY,FAM83D,FAM110C,NEK2,TUBG1,AURKA,NDE1,RGS14,WDR62 |
| 4.064e-03 | -5.51 | MODULE_37 | MSigDB lists | MODULE_37 | 438 | 61 | 17758 | 1761 |
LMO7,LMTK3,CDH22,AASS,TSC22D3,SLC25A27,TP53,C6orf106,NDRG2,CTSZ,ISYNA1,NANS,BARD1,IL18R1,CMTM6,C9orf69,TFAP4,RNF220,CYP1A1,RALGPS2,CDK16,CD9,UBE2J1,ESPN,PDE4D,CITED2,SCARA3,FAR2,ABCC1,ATG4D,GCA,TIMP2,TBC1D8B,FMN1,ADCK3,MICB,SNTB2,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,GALNT3,PTPRF,AMZ2,ENPP1,NEIL1,CSF1,SLC9A6,PLEKHG1,S100A5,FGD6,TMEM120A,RARG,PKIA,RRAGD,PCSK5 |
| 4.067e-03 | -5.50 | TM4_1 | prosite domains | PS00421 | 21 | 7 | 11866 | 1235 |
TSPAN1,CD63,TSPAN6,TSPAN7,CD82,TSPAN18,CD9 |
| 4.067e-03 | -5.50 | FE2OG_OXY | prosite domains | PS51471 | 21 | 7 | 11866 | 1235 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 4.088e-03 | -5.50 | central_nervous_system-thalamus-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-oligoastrocytoma_Grade_III | 22 | 7 | 17775 | 1757 |
CSTF2,PYGO1,PHLDA1,PPP2R3A,XYLT1,MELK,TP53 |
| 4.088e-03 | -5.50 | thymus | COSMIC cancer mutations | thymus | 22 | 7 | 17775 | 1757 |
ERBB2,SS18,AKT1,PTEN,RET,PIK3CA,TP53 |
| 4.097e-03 | -5.50 | Integrated Breast Cancer Pathway | WikiPathways | WP1984 | 152 | 29 | 4455 | 516 |
SIRT1,GRN,PLK1,CASP3,AKT1,CASP9,TP53,TGFBR1,BARD1,DAG1,RHEB,CCND1,WEE1,NCOA3,CDH1,JAK1,PTEN,BAX,HDAC1,DHTKD1,AURKA,SELK,ZMIZ1,RASGEF1A,MYT1,AHR,NUP85,APOBEC3G,PKIA |
| 4.100e-03 | -5.50 | ATPase activity, coupled to transmembrane movement of substances | molecular function | GO:0042626 | 105 | 20 | 16491 | 1673 |
ATP8A1,ATP2C2,TAP1,ABCG2,ATP1B1,ABCD4,ATP13A2,TAPBP,ATP6V0B,ATP1A1,ATP7B,PCYOX1,ABCA2,ABCB1,ABCD1,ATP1B3,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 4.100e-03 | -5.50 | clear_cell | COSMIC cancer mutations | clear_cell | 12 | 5 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,PIK3CA |
| 4.100e-03 | -5.50 | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | 12 | 5 | 17775 | 1757 |
GNAS,AKT1,IDH1,RET,PIK3CA |
| 4.100e-03 | -5.50 | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | 12 | 5 | 17775 | 1757 |
GNAS,AKT1,IDH1,RET,PIK3CA |
| 4.115e-03 | -5.49 | BASSO_B_LYMPHOCYTE_NETWORK | MSigDB lists | BASSO_B_LYMPHOCYTE_NETWORK | 137 | 24 | 17758 | 1761 |
BIN1,SUN2,DDB2,HLA-E,S100A4,SAT1,LITAF,TGOLN2,IL27RA,ITPR2,CCNB1,MYL12A,CDK1,CASP4,PRDX4,PSMD1,SLC25A4,SP100,ITPR1,SLC4A3,TUBG1,ARVCF,MDFIC,PLCB2 |
| 4.125e-03 | -5.49 | inositol phosphate metabolic process | biological process | GO:0043647 | 57 | 13 | 16441 | 1675 |
CALM2,PLCH1,PLCG1,PTEN,INPP5D,CALM1,PLCG2,INPP4B,CALM3,ISYNA1,ITPKA,MINPP1,PLCB2 |
| 4.138e-03 | -5.49 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2284 | 262 | 17775 | 1757 |
ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,PPFIBP2,SYTL4,PLXNA1,CA8,SLC9A7,CYP1A1,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,POR,COL12A1,AHRR,PLCG1,DNM1L,ATP7B,PRDM5,FAM110C,TANC2,TRAF5,GAB1,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,FAM21C,MECOM,RALGPS2,FRY,FAM189A1,BDH1,PRKG1,MAP3K9,SORL1,CADPS2,CACNA1D,RIMS2,MCCC2,PAQR7,EPB41L5,STAT4,GNA11,AP1AR,SLCO4A1,PLEKHH2,PRKAG2,FAAH,PCDH19,IFIH1,XDH,ADAMTS16,PLA2G4A,TCTN2,IQGAP1,PKP2,RNF182,GRK6,CD274,APC2,TNFSF9,ZNF385B,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,COG2,PTPN9,SYNE2,UTRN,ITPR3,ALCAM,TRIQK,ATP10D,CMTM7,NIN,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,DENND5B,EPS8,DNAH3,SRPX2,HOXB2,TMEM87B,ITGB8,ANKS1B,PTEN,ARSG,FUT8,ATP8B1,FAM102A,TRIM62,NCOA2,PDGFC,ARHGEF28,MRS2,PIK3R1,DIAPH2,C2orf69,AIF1L,SNTB1,GALNT3,PPM1H,GRIN2D,ITGAV,USF2,ARSB,ESPL1,JARID2,RGMA,LTBP1,ARFGEF1,NENF,MPP5,TEX2,ITPR2,DNER,CACNB4,NUP62CL,TMC1,KREMEN1,NKAIN3,SIPA1L2,HSF2,SHC3,ANKFN1,PHTF1,SLC44A1,PAPSS1,TRPC1,POF1B,ANO4,TRAM1,MYRIP,ZNF462,CR2,IDH1,ADRBK2,DZIP1L,KCNMB4,HPSE,MAP2,HOXA9,EPB41L4A,CPPED1,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,TNS3,DAZAP1,IGF1R,FRAS1,MDFIC,LIMCH1,PIM1,ZRANB1,ALDH3A2,CHSY3,CORO2A,MGAT4B,PDE5A,EIF2AK1,SCRIB,HEATR5A,MFSD7,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,GAS2L1,LMO7,NCKAP5,XYLT1,TP53,PDIA5,SLC25A48,CDH3,DIXDC1,NOTCH3,CPD,CLCN3,TMTC1,AKT1,PTPRU,SLC39A8,DUSP4,DOCK5,FANCE,DNAJC10,PTPRJ,ABHD12,C19orf66,TLE1,EFNA5,SPTBN5,CYP2U1,LTA4H,COL9A3,GOLIM4,PACSIN2,CDH22,ARHGEF11,LRP4,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,MLPH,BMP7,TOX2,KIAA0319,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,DEPDC4,GCLC,RC3H2,MAML2,FNDC3A,ARHGAP24,BANK1,RAP2C,UACA,CLIP4,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 4.138e-03 | -5.49 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2284 | 262 | 17775 | 1757 |
ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,PPFIBP2,SYTL4,PLXNA1,CA8,SLC9A7,CYP1A1,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,POR,COL12A1,AHRR,PLCG1,DNM1L,ATP7B,PRDM5,FAM110C,TANC2,TRAF5,GAB1,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,FAM21C,MECOM,RALGPS2,FRY,FAM189A1,BDH1,PRKG1,MAP3K9,SORL1,CADPS2,CACNA1D,RIMS2,MCCC2,PAQR7,EPB41L5,STAT4,GNA11,AP1AR,SLCO4A1,PLEKHH2,PRKAG2,FAAH,PCDH19,IFIH1,XDH,ADAMTS16,PLA2G4A,TCTN2,IQGAP1,PKP2,RNF182,GRK6,CD274,APC2,TNFSF9,ZNF385B,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,COG2,PTPN9,SYNE2,UTRN,ITPR3,ALCAM,TRIQK,ATP10D,CMTM7,NIN,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,DENND5B,EPS8,DNAH3,SRPX2,HOXB2,TMEM87B,ITGB8,ANKS1B,PTEN,ARSG,FUT8,ATP8B1,FAM102A,TRIM62,NCOA2,PDGFC,ARHGEF28,MRS2,PIK3R1,DIAPH2,C2orf69,AIF1L,SNTB1,GALNT3,PPM1H,GRIN2D,ITGAV,USF2,ARSB,ESPL1,JARID2,RGMA,LTBP1,ARFGEF1,NENF,MPP5,TEX2,ITPR2,DNER,CACNB4,NUP62CL,TMC1,KREMEN1,NKAIN3,SIPA1L2,HSF2,SHC3,ANKFN1,PHTF1,SLC44A1,PAPSS1,TRPC1,POF1B,ANO4,TRAM1,MYRIP,ZNF462,CR2,IDH1,ADRBK2,DZIP1L,KCNMB4,HPSE,MAP2,HOXA9,EPB41L4A,CPPED1,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,TNS3,DAZAP1,IGF1R,FRAS1,MDFIC,LIMCH1,PIM1,ZRANB1,ALDH3A2,CHSY3,CORO2A,MGAT4B,PDE5A,EIF2AK1,SCRIB,HEATR5A,MFSD7,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,GAS2L1,LMO7,NCKAP5,XYLT1,TP53,PDIA5,SLC25A48,CDH3,DIXDC1,NOTCH3,CPD,CLCN3,TMTC1,AKT1,PTPRU,SLC39A8,DUSP4,DOCK5,FANCE,DNAJC10,PTPRJ,ABHD12,C19orf66,TLE1,EFNA5,SPTBN5,CYP2U1,LTA4H,COL9A3,GOLIM4,PACSIN2,CDH22,ARHGEF11,LRP4,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,MLPH,BMP7,TOX2,KIAA0319,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,DEPDC4,GCLC,RC3H2,MAML2,FNDC3A,ARHGAP24,BANK1,RAP2C,UACA,CLIP4,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 4.139e-03 | -5.49 | GSE2826_WT_VS_XID_BCELL_DN | MSigDB lists | GSE2826_WT_VS_XID_BCELL_DN | 191 | 31 | 17758 | 1761 |
LAMP2,CPD,TM2D2,IGFBP6,EPAS1,HEBP1,ABCG2,GLO1,F12,ATP1B1,DOCK5,MAP3K6,VPS26A,GLCE,MESDC2,SNTA1,MAPKAPK2,GALNT3,PDGFA,P4HA2,AXL,SERPINB6,CDK18,CTSA,TMEM37,ECE1,UBE2C,CDKN2D,SLC12A2,PTGES,CBX7 |
| 4.139e-03 | -5.49 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 191 | 31 | 17758 | 1761 |
GAA,MTM1,ADD1,IQGAP1,SYNE2,NDC80,CAMK1D,FAM101B,STK17B,CYP4F3,PRRG4,IRF2BPL,MARCH8,NUDT16,NUCB1,CPNE2,ADD3,METTL7A,ZFP36,ATP7B,RAB11FIP1,FAM117A,CAB39,RELL1,PHKA2,TOB1,DCBLD1,S100A6,CAPN1,MYO5A,CD33 |
| 4.146e-03 | -5.49 | AhR pathway | WikiPathways | WP2100 | 29 | 9 | 4455 | 516 |
AHRR,HES1,CYP1A1,NQO1,BAX,CDKN1B,AHR,AIP,CYP1B1 |
| 4.149e-03 | -5.48 | Regulation of PLK1 Activity at G2/M Transition | REACTOME pathways | R-HSA-2565942 | 81 | 17 | 8202 | 867 |
PLK1,CEP70,PRKAR2B,CCNB1,BORA,PRKACA,CDK1,OPTN,CNTRL,CEP78,PLK4,NEK2,AURKA,TUBG1,NDE1,CEP41,CCNB2 |
| 4.149e-03 | -5.48 | POLO_BOX | prosite domains | PS50078 | 4 | 3 | 11866 | 1235 |
PLK1,PLK2,PLK4 |
| 4.149e-03 | -5.48 | LAMP_3 | prosite domains | PS51407 | 4 | 3 | 11866 | 1235 |
LAMP2,LAMP1,LAMP3 |
| 4.149e-03 | -5.48 | AMOP | prosite domains | PS50856 | 4 | 3 | 11866 | 1235 |
SUSD2,MUC4,ISM1 |
| 4.151e-03 | -5.48 | WEST_ADRENOCORTICAL_TUMOR_DN | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_DN | 533 | 72 | 17758 | 1761 |
PLA2G4A,SORBS1,NDRG2,PHLDA1,IER3,NOV,ZFP36,FOSB,AOX1,AKR1B1,CTTN,CTH,SEMA3B,SIRT1,SSH3,CD55,SEPT6,LYRM1,CASP9,PLEKHO1,PTGER4,TNS1,ASB13,NEIL1,SLC25A4,AXL,KLF5,KLF11,MAFF,ABCA1,ARHGEF3,IGFBP6,ALDH6A1,SOX9,CYB561,NKRF,FBLN1,SIRPA,WWP2,IL17RB,RPL39,CALD1,FUT8,COL6A1,ERBB3,MYLIP,ALDH3A2,RIMS2,FAH,DLGAP1,OPLAH,KLK5,FBLN5,ADCK3,NR4A1,OXR1,FOS,LEPR,CRISPLD2,FAS,EPN3,FAAH,CSF1,ABCB1,NR4A3,NR4A2,PLD1,FHL1,ATP1B3,GEM,TOB1,ABCG1 |
| 4.159e-03 | -5.48 | MCBRYAN_TERMINAL_END_BUD_UP | MSigDB lists | MCBRYAN_TERMINAL_END_BUD_UP | 12 | 5 | 17758 | 1761 |
TNFRSF12A,TNS1,IGFBP2,SDC1,CDK1 |
| 4.159e-03 | -5.48 | ACTIN_FILAMENT_BUNDLE_FORMATION | MSigDB lists | ACTIN_FILAMENT_BUNDLE_FORMATION | 12 | 5 | 17758 | 1761 |
ARHGEF10L,EZR,SORBS1,NF2,SHROOM2 |
| 4.159e-03 | -5.48 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | MSigDB lists | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | 12 | 5 | 17758 | 1761 |
CALM2,CALM3,AKT1,SPR,CALM1 |
| 4.163e-03 | -5.48 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | 22 | 7 | 17758 | 1761 |
SGK1,HLF,TIMP3,GEM,WDR44,RASGRP1,MITF |
| 4.163e-03 | -5.48 | PID_PDGFRA_PATHWAY | MSigDB lists | PID_PDGFRA_PATHWAY | 22 | 7 | 17758 | 1761 |
PLCG1,ITGAV,JAK1,ELK1,FOS,PIK3R1,PIK3CA |
| 4.163e-03 | -5.48 | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | MSigDB lists | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | 22 | 7 | 17758 | 1761 |
AURKA,KIF23,CCNF,CCNB1,UBE2C,CDC20,CKS2 |
| 4.163e-03 | -5.48 | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | MSigDB lists | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | 22 | 7 | 17758 | 1761 |
BCL2L1,TXN,SLC25A4,PRKACA,GPX4,PRKG1,BAX |
| 4.163e-03 | -5.48 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | 93 | 18 | 17758 | 1761 |
LAMP2,THRB,ANXA3,PPP4R4,TRIM2,CYB5R2,AMDHD1,IL17RB,APLP2,CDH1,SERPINA1,CA2,LYPD6,BHLHE41,ISM1,ELF5,SGK3,SORL1 |
| 4.167e-03 | -5.48 | MORI_PRE_BI_LYMPHOCYTE_DN | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_DN | 72 | 15 | 17758 | 1761 |
AKIRIN1,GNS,ATP6V0B,RALGPS2,ZFP36,LPGAT1,CASP9,AIM1,SAT1,NFKBIZ,RGS14,TRAF5,ERP29,CAPN1,JARID2 |
| 4.167e-03 | -5.48 | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 72 | 15 | 17758 | 1761 |
PLA2G4A,CCND1,PRSS23,AK7,BHLHB9,PLK2,RET,RAB20,KIF13A,PM20D2,TLN2,ALCAM,SERPINB1,KLF7,RRAGD |
| 4.167e-03 | -5.48 | chr8p21 | MSigDB lists | chr8p21 | 72 | 15 | 17758 | 1761 |
NKX3-1,ZNF395,PBK,KIF13B,BMP1,RHOBTB2,ASAH1,NRG1,LOXL2,C8orf58,SCARA3,REEP4,DOCK5,KCTD9,SH2D4A |
| 4.169e-03 | -5.48 | V$AP4_Q5 | MSigDB lists | V$AP4_Q5 | 255 | 39 | 17758 | 1761 |
SLC25A24,DHRS3,TNFRSF19,PDGFB,PSIP1,SYTL2,IRF2BPL,TFAP4,ADRBK1,PHF7,STIM1,REEP1,ANKRD12,ATRNL1,VAT1,ERBB3,ZRANB1,CITED2,SULT2B1,TRAM1,TRIM62,DOCK4,MAP3K3,SMARCA2,MBP,PLEKHA6,RGAG1,PRICKLE1,PRKCQ,TCF7,TP53INP2,ABR,ARHGAP24,PGF,PTK7,NR4A3,RHOBTB2,GRIN2D,ZMIZ1 |
| 4.170e-03 | -5.48 | - | gene3d domains | 1.10.565.10 | 48 | 12 | 9988 | 1080 |
THRB,NR1D2,NR3C1,NR4A1,THRA,NR4A3,PPARA,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 4.173e-03 | -5.48 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 160 | 27 | 17758 | 1761 |
MRC2,TSC22D3,HAL,COL4A5,TGOLN2,ATP1B1,ZFAND5,FOS,ALCAM,STK17B,IRS2,ZFP36,SIPA1L1,FOSB,NFKBIA,SORL1,NR4A2,NDE1,CITED2,TRAM1,PTPRE,MYLIP,SPRY2,ABCA1,NCOA2,CD33,TMEM131 |
| 4.183e-03 | -5.48 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | 52 | 12 | 17758 | 1761 |
PLK1,CDKN2C,FAM111A,TIMM8A,CDC20,NDC80,AURKA,CCNF,DHRS3,BARD1,ESPL1,E2F8 |
| 4.198e-03 | -5.47 | cyclin-dependent protein serine/threonine kinase regulator activity | molecular function | GO:0016538 | 27 | 8 | 16491 | 1673 |
CCNE2,CCND1,CDKN2C,CASP3,CDKN1C,CDKN1B,CDKN2D,CKS2 |
| 4.205e-03 | -5.47 | stress-activated protein kinase signaling cascade | biological process | GO:0031098 | 156 | 27 | 16441 | 1675 |
RHOA,RIPK2,RPS6KA1,PTGER4,STRADB,PKN1,DUSP4,ELK1,FOS,TNFRSF19,MAP3K6,MAPK8IP1,MAPKAPK2,RPS6KA2,STK26,NOD2,MAP3K9,AKR1B1,DUSP10,DAB2IP,STK39,MDFIC,MAPK11,MAP3K5,GAB1,SYK,MDFI |
| 4.205e-03 | -5.47 | regulation of organ morphogenesis | biological process | GO:2000027 | 156 | 27 | 16441 | 1675 |
HES1,CTHRC1,RUNX2,HOXB7,LGR4,SOX9,ETV5,POR,NFIB,FZD6,SIX4,PDGFA,FGFR2,BMP7,PTK7,CSF1,BAX,TFAP2A,TACSTD2,SP6,NTN4,TWIST1,CITED2,SOX8,WNT3A,ETV4,DVL2 |
| 4.211e-03 | -5.47 | interferon-gamma-mediated signaling pathway | biological process | GO:0060333 | 77 | 16 | 16441 | 1675 |
TRIM8,HLA-E,HLA-F,TRIM68,HLA-A,SOCS3,HLA-B,JAK1,SP100,TRIM21,IRF2,IRF7,OAS3,HLA-C,NCAM1,TRIM62 |
| 4.213e-03 | -5.47 | regulation of transporter activity | biological process | GO:0032409 | 194 | 32 | 16441 | 1675 |
TCAF1,FXYD3,CALM3,ANO9,PRKACA,CACNB4,WWP2,CALM2,GNB5,STIM1,CABP1,PLCG2,DAPK1,SGK3,SGK1,FXYD5,TWIST1,PDE4D,CACNA1D,MYO5A,CHP1,PPIF,RASGRF1,CALM1,UTRN,ATP1B1,NETO2,CAB39,STK39,FHL1,ATP1B3,NDFIP1 |
| 4.218e-03 | -5.47 | MORF_DAP | MSigDB lists | MORF_DAP | 79 | 16 | 17758 | 1761 |
SYPL1,DAP,CALM1,CALM3,ERP29,BCAP31,ARF4,VPS26A,CALM2,DDOST,GDE1,TMBIM6,MDH1,TECR,GPX4,KDELR1 |
| 4.218e-03 | -5.47 | MORI_PRE_BI_LYMPHOCYTE_UP | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_UP | 79 | 16 | 17758 | 1761 |
HMMR,TXN,CDC20,MGST2,H2AFV,CDK1,PRDX4,TOP2A,IDE,DBI,CDCA5,AURKA,CCNB2,UBE2C,E2F8,MELK |
| 4.240e-03 | -5.46 | Inflammatory mediator regulation of TRP channels | KEGG pathways | ko04750 | 98 | 20 | 6908 | 758 |
PLA2G4A,CALM1,PIK3R1,PTGER4,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNAS,CALM2,PLCG1,PLCG2,ITPR1,PIK3CA,MAPK11,PIK3CD,F2RL1,PLCB2,MAPK12 |
| 4.240e-03 | -5.46 | Inflammatory mediator regulation of TRP channels | KEGG pathways | hsa04750 | 98 | 20 | 6908 | 758 |
PLA2G4A,CALM1,PIK3R1,PTGER4,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNAS,CALM2,PLCG1,PLCG2,ITPR1,PIK3CA,MAPK11,PIK3CD,F2RL1,PLCB2,MAPK12 |
| 4.266e-03 | -5.46 | CH | smart domains | SM00033 | 66 | 15 | 9131 | 997 |
LMO7,GAS2L1,SMTNL2,ASPM,IQGAP1,SYNE2,UTRN,CLMN,SPTBN5,DIXDC1,LIMCH1,TAGLN2,IQGAP3,SPTB,PLS3 |
| 4.276e-03 | -5.45 | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 168 | 28 | 17758 | 1761 |
HES1,B3GNT2,TXN,RIPK2,RAPGEF2,PLAUR,PTGER4,IL18,CD274,OSR2,SAV1,CDK1,CD83,SOCS3,IER3,BTG3,E2F7,ETS2,MFSD2A,NFKBIA,RAP2C,FJX1,DRAM1,SELK,NFKBIZ,HS3ST3B1,PLD1,MAFF |
| 4.278e-03 | -5.45 | transmembrane receptor protein tyrosine kinase activity | molecular function | GO:0004714 | 64 | 14 | 16491 | 1673 |
EPHA10,IGF1R,FGFR2,AXL,EPHA4,RET,RYK,ERBB2,ROR1,EPHA1,EPHB4,MERTK,DDR1,NRP2 |
| 4.280e-03 | -5.45 | defense response | biological process | GO:0006952 | 1606 | 195 | 16441 | 1675 |
SIGIRR,TXN,LGR4,AK7,DNAJC3,LMCD1,TAP1,NRG2,F11R,PSME1,IL18,ITPR2,CAMK1D,PDGFB,SDC1,SPTB,TRIM68,CALM2,PSMD1,RPS6KA2,SHC3,ELMO2,IL31RA,PIK3CA,AOX1,IRF2,PIK3CD,APOBEC3G,RASGRP1,NLRP4,CD55,TRIM8,TNIP1,ITCH,USP18,CASP9,NFE2L1,CR2,SLC35C1,AGO4,PRKAR2B,F12,RNF19B,OPTN,MDK,PLCG1,LIMK1,NOD2,NFKBIZ,F2RL1,GAB1,DDX58,LGALS3,THEMIS2,HLA-E,RASA2,HLA-F,RAB23,CALM3,TEC,NCKAP1,SLC1A3,PHLPP1,MECOM,ELF3,RPL39,KCNN4,FAM13B,DAPK1,TPST1,AHCY,ALPK1,HLA-C,NCAM1,ULBP2,MICB,CALM1,ANO6,EIF2AK1,ELK1,IFIT3,PSMA4,RASA1,FAS,MAPKAPK2,PELI2,PHLPP2,CSF1,NFKBIA,RAET1L,ITPR1,NLRC5,MDH1,PLD1,ARPC2,MAP3K5,IFIH1,JAK3,APOL2,IFI6,TMEM173,SPRED1,NLRX1,IL15,RPS6KA1,PSME2,ERBB2,IL27RA,SLC7A2,BCL2L1,PRKACA,APOBEC3B,PDGFA,SP100,CYP4F11,PLCG2,BCL6,CDKN1B,DAB2IP,IFIT1,OAS3,RASGEF1A,LGMN,F2R,FRS3,MX1,RIPK2,AKT1,APOBEC3D,PRKCQ,ATP1B1,ITPR3,DUSP4,CD40,SOCS3,IRS2,DDOST,JAK1,AXL,NRG1,IRF7,SPTBN5,LTA4H,ANXA3,TNRC6C,HERC5,PSMD10,APOBEC3H,FGF19,LGALS3BP,HLA-A,HDAC9,CTNNBIP1,IL17RB,FAM111A,CXCL16,ADORA1,ADRBK1,PTEN,CST3,ADAM15,TRIM21,MAPK11,ERBB3,CNPY3,SYK,TRIM62,RASGRF1,PLSCR1,PSMB4,IFITM3,RAPGEF2,NR4A1,PIK3R1,NUB1,GRIN1,PARP4,FBXO9,YES1,FOS,CD83,CTSL,HLA-B,SERPINA1,HCP5,FGFR2,SCG2,PRCP,DBI,NMI,DTX4,GRIN2D,GPER1,ICOSLG,PTGES |
| 4.304e-03 | -5.45 | cytokinesis | biological process | GO:0000910 | 84 | 17 | 16441 | 1675 |
PLK1,RHOA,KIF20A,ARHGEF11,KLHL13,CKAP2,CIT,SEPT6,DIAPH2,KIF23,KIF13A,NUSAP1,BCL2L1,ANLN,RASA1,SNX18,ESPL1 |
| 4.309e-03 | -5.45 | lung cell differentiation | biological process | GO:0060479 | 27 | 8 | 16441 | 1675 |
THRB,GRHL2,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB |
| 4.309e-03 | -5.45 | positive regulation of release of cytochrome c from mitochondria | biological process | GO:0090200 | 27 | 8 | 16441 | 1675 |
PPIF,PINK1,BMF,DNM1L,PLAUR,TP53,BAX,GPER1 |
| 4.317e-03 | -5.45 | negative regulation of neuron apoptotic process | biological process | GO:0043524 | 134 | 24 | 16441 | 1675 |
GCLM,PINK1,RHOA,CPEB4,GCLC,OXR1,GRIN1,BCL2L1,RASA1,SIX4,OPTN,MDK,BHLHB9,AXL,WFS1,KIF14,PIK3CA,BAX,NR4A3,NR4A2,ERBB3,LGMN,UNC5B,F2R |
| 4.321e-03 | -5.44 | CRMPs in Sema3A signaling | REACTOME pathways | R-HSA-399956 | 16 | 6 | 8202 | 867 |
DPYSL5,PLXNA1,SEMA3A,DPYSL2,CDK5R1,DPYSL3 |
| 4.326e-03 | -5.44 | RB_P130_DN.V1_DN | MSigDB lists | RB_P130_DN.V1_DN | 130 | 23 | 17758 | 1761 |
LAMP1,LAMP2,PVRL4,SEC23A,USP18,ABCG2,KLK6,GLO1,ASB13,IDH1,RASA1,KIAA1161,GNS,ARHGAP24,RCN1,CTSC,RAP2C,ERAP1,KLK7,SELK,LIFR,C9orf72,PARP9 |
| 4.333e-03 | -5.44 | lipid binding | molecular function | GO:0008289 | 642 | 86 | 16491 | 1673 |
PLA2G4A,MTM1,TRIP10,IQGAP1,ITPR2,SYTL4,MVB12B,CYP26A1,ZFYVE9,SYTL2,ZFYVE16,OSBPL3,PAQR5,FABP6,PASK,SNX16,DAB2IP,ACOX2,PACSIN1,TIAM1,SNX10,S100A13,RASGRP1,CD55,MCTP1,AKT1,ITPR3,SNX12,ATP1A1,DNM1L,WIPI1,AXL,INPP4B,PIK3C2B,ANXA9,SYT13,PXDC1,NRGN,NR3C2,ABCA1,ANXA3,ARAP3,PACSIN2,SELL,TEC,CRABP2,FAM21C,SNX18,PTEN,BAX,SGK3,ATP8B1,PLEKHF1,CADPS2,SYTL3,CCDC88A,PAQR7,SNX7,CYP26B1,ACBD5,ARAP2,PSMB4,NR3C1,RAPGEF2,AMER1,PPARA,NPC2,PCTP,CPTP,STX3,RASGRP2,EPN3,SYT7,DBI,ITPR1,PGRMC1,PITPNA,PLD1,GPER1,WDR45B,APOL2,SNX30,MELK,ESYT2,ABCG1,PROM2 |
| 4.338e-03 | -5.44 | Activation of CaMK IV | REACTOME pathways | R-HSA-442745 | 4 | 3 | 8202 | 867 |
CALM3,CALM2,CALM1 |
| 4.353e-03 | -5.44 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | 595 | 79 | 17758 | 1761 |
CCNE2,AVPI1,DLGAP5,NQO1,HOXB7,CUL4B,LACTB2,CCNB1,DPP8,STIL,CENPN,TNFSF9,FANCI,SS18,BTG3,IL6ST,FRYL,OSBPL3,KIF14,PHTF1,TUBG1,GOT1,HYLS1,MYBL1,CKS2,SGCE,FIGNL1,OSTM1,PBK,ITCH,NUSAP1,ROR1,ANLN,CDK1,DNAJC10,IDE,RBL1,DNM1L,ZNF367,P4HA2,SIPA1L1,C1orf43,DENND5B,ENO2,CKAP2,CIT,GPSM2,TIPRL,KIF5B,RALGPS2,CTSC,TOX2,TNFRSF12A,IQGAP3,LRIF1,SGCB,CCDC88A,GFPT1,HPS3,ZWINT,PLAUR,CCDC34,AK4,AP1AR,KBTBD2,TMEM30A,NETO2,AURKA,PPP2R3C,CTSA,DONSON,SPCS3,ATP1B3,NDE1,PLOD3,ARSB,UBE2C,ACOT7,EGLN1 |
| 4.361e-03 | -5.44 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 176 | 29 | 17758 | 1761 |
PCGF5,TRIM8,ARHGEF3,RUNX2,NFKBIE,TACC1,SNTB2,SAT1,UTRN,SERTAD3,NFE2L1,LMCD1,GRK6,CENPN,PRRG4,HLA-A,GALNT3,DTX3L,TRANK1,CTSC,RGS3,NMI,MITF,SECTM1,PLEKHG1,CCDC69,IFIH1,MAFF,PARP9 |
| 4.373e-03 | -5.43 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 272 | 41 | 17758 | 1761 |
ANXA3,LTBP1,FBLIM1,ARAP3,PSME2,LRP4,CALM3,ETS1,ANO1,CALM2,TOP2A,APOBEC3B,PSMD1,CALD1,TUBG1,NCAM1,HMMR,PSMB4,PRSS23,TACC1,PBK,CALM1,MYEOV,EZR,NEURL1B,CDK1,PSMA4,COL12A1,CMTM7,STK17A,IDE,RND3,AXL,PGM2L1,DONSON,GDF11,CCNB2,F2RL1,ABCA1,ACOT7,KLF7 |
| 4.383e-03 | -5.43 | thymic_carcinoma | COSMIC cancer mutations | thymic_carcinoma | 17 | 6 | 17775 | 1757 |
ERBB2,AKT1,PTEN,RET,PIK3CA,TP53 |
| 4.383e-03 | -5.43 | thymus-thymoma | COSMIC cancer mutations | thymus-thymoma | 17 | 6 | 17775 | 1757 |
ERBB2,AKT1,PTEN,RET,PIK3CA,TP53 |
| 4.383e-03 | -5.43 | thymoma | COSMIC cancer mutations | thymoma | 17 | 6 | 17775 | 1757 |
ERBB2,AKT1,PTEN,RET,PIK3CA,TP53 |
| 4.383e-03 | -5.43 | anaplastic | COSMIC cancer mutations | anaplastic | 17 | 6 | 17775 | 1757 |
CDKN2C,NF2,AKT1,IDH1,PTEN,PIK3CA |
| 4.396e-03 | -5.43 | negative regulation of ERK1 and ERK2 cascade | biological process | GO:0070373 | 51 | 12 | 16441 | 1675 |
TNIP1,DLG1,NDRG2,ARRB1,EZR,DAB2IP,GPER1,RGS14,GSTP1,FBLN1,RANBP9,SPRY2 |
| 4.399e-03 | -5.43 | STRDHORMONER | prints domains | PR00398 | 47 | 11 | 4759 | 462 |
THRB,NR1D2,NR3C1,NR4A1,THRA,NR4A3,PPARA,NR4A2,RARG,NR2C1,NR2C2 |
| 4.428e-03 | -5.42 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | 184 | 30 | 17758 | 1761 |
GAA,OPLAH,HECA,PLEKHA6,TTC39B,ADCK3,GGA1,PANK1,ARL4C,ARFRP1,ASB13,BBS2,SLC20A1,SOCS3,TFAP4,MAN2A2,AIM1L,ATP6V0B,OTUD1,ITGA3,AGPAT2,NR1D2,BCL6,RFX5,NOTCH3,MYLIP,SMYD5,SPRY2,CBX7,ARHGEF4 |
| 4.430e-03 | -5.42 | MITOTIC_CELL_CYCLE | MSigDB lists | MITOTIC_CELL_CYCLE | 153 | 26 | 17758 | 1761 |
PLK1,SUN2,ZWINT,DLGAP5,CDKN1C,CIT,NDC80,KIF23,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDKN2C,BTG3,CDCA5,DLG1,NEK2,CDKN1B,AURKA,BUB1,CENPE,UBE2C,CDKN2D,MPHOSPH9,ESPL1 |
| 4.455e-03 | -5.41 | Cyclin_C-dom | interpro domains | IPR004367 | 17 | 6 | 18293 | 1814 |
CCNE2,CCNJL,CCND1,CCNF,CCNB1,CCNB2 |
| 4.455e-03 | -5.41 | Sulfatase | interpro domains | IPR000917 | 17 | 6 | 18293 | 1814 |
GNS,ARSB,ARSK,ARSG,GALNS,SULF2 |
| 4.455e-03 | -5.41 | FARMER_BREAST_CANCER_CLUSTER_7 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_7 | 17 | 6 | 17758 | 1761 |
ECI2,CDH1,ALCAM,DHRS2,TMEM41B,BLVRB |
| 4.455e-03 | -5.41 | SIMBULAN_PARP1_TARGETS_DN | MSigDB lists | SIMBULAN_PARP1_TARGETS_DN | 17 | 6 | 17758 | 1761 |
TAGLN2,NCAM1,CCNB1,CCNB2,CDC20,PRIM1 |
| 4.455e-03 | -5.41 | TOMIDA_METASTASIS_DN | MSigDB lists | TOMIDA_METASTASIS_DN | 17 | 6 | 17758 | 1761 |
ENO2,LGALS3,CDH1,NR4A1,SAT1,SYBU |
| 4.455e-03 | -5.41 | SISTER_CHROMATID_SEGREGATION | MSigDB lists | SISTER_CHROMATID_SEGREGATION | 17 | 6 | 17758 | 1761 |
NUSAP1,CENPE,ZWINT,ESPL1,CDCA5,NDC80 |
| 4.455e-03 | -5.41 | MODULE_492 | MSigDB lists | MODULE_492 | 17 | 6 | 17758 | 1761 |
FUCA1,ASAH1,CTSA,GLA,NAGA,HEXB |
| 4.455e-03 | -5.41 | ONDER_CDH1_TARGETS_3_UP | MSigDB lists | ONDER_CDH1_TARGETS_3_UP | 17 | 6 | 17758 | 1761 |
KLF9,ALDH6A1,WIPI1,TSC22D3,LEPR,CYP1B1 |
| 4.455e-03 | -5.41 | GENTILE_UV_RESPONSE_CLUSTER_D1 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D1 | 17 | 6 | 17758 | 1761 |
CASP3,WEE1,GEM,RND3,ITGA6,STX3 |
| 4.455e-03 | -5.41 | KAPOSI_LIVER_CANCER_MET_UP | MSigDB lists | KAPOSI_LIVER_CANCER_MET_UP | 17 | 6 | 17758 | 1761 |
FGD6,HMGA1,ITGAV,CD63,CKS2,MDFI |
| 4.455e-03 | -5.41 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | MSigDB lists | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | 17 | 6 | 17758 | 1761 |
CALM2,CALM3,GRIN2D,RASGRF1,CALM1,GRIN1 |
| 4.455e-03 | -5.41 | POSITIVE_REGULATION_OF_JNK_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_JNK_ACTIVITY | 17 | 6 | 17758 | 1761 |
MDFIC,MAP3K5,PKN1,MAP3K6,MDFI,MAP3K9 |
| 4.462e-03 | -5.41 | RASA1 (RAS p21 protein activator (GTPase activating protein) 1) | protein interactions | 5921 | 80 | 17 | 16036 | 1726 |
CASP3,PIK3R1,ERBB2,YES1,SLC9A2,RASA1,WWP2,ARHGAP35,SOCS3,PLCG1,IGF1R,DOK4,NFKBIA,AURKA,WWP1,ERBB3,SYK |
| 4.462e-03 | -5.41 | RPS6KA1 (ribosomal protein S6 kinase, 90kDa, polypeptide 1) | protein interactions | 6195 | 80 | 17 | 16036 | 1726 |
GRN,NR4A1,MPP1,RPS6KA1,FOS,GNS,CARHSP1,RPS6KA2,NFKBIA,MITF,NR4A3,CDKN1B,NR4A2,L1CAM,TOB1,SYK,CAPN1 |
| 4.477e-03 | -5.41 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2976 | 334 | 17775 | 1757 |
HECA,ACACB,GAA,PPP4R4,ATP8A1,TSC22D3,TAP1,NRG2,CCNB1,DPP8,FAM46C,CDKN2C,DAPK2,CTGF,KIAA1107,STIM1,IQCE,CABP1,PAQR5,IL31RA,AOX1,STEAP2,PIK3CA,ATRNL1,MTMR11,TMEM37,TIAM1,XKR8,SPEF2,HSPA12A,TNS1,LDB2,SPNS3,ABR,ARHGEF26,AHRR,ANKRD6,ATP7B,LRIG1,FAM114A1,NOD2,PRDM5,RELL1,GAB1,DDX58,SCN5A,MRC2,FRMD4A,CDKN1C,TBC1D1,CALB2,MTL5,SLC1A3,MERTK,RAVER2,DOPEY2,RALGPS2,FRY,ITGA3,FAM189A1,MEGF8,PRKG1,SORL1,CADPS2,CACNA1D,PIKFYVE,RIMS2,MCCC2,TRAK2,PRODH,KCNJ12,KLK5,LPGAT1,MYBL2,ATP8B3,NPHP3,SFXN5,NFIB,DCP2,FAS,CACHD1,AP1AR,PLEKHH2,FAAH,ISM1,TCEAL4,NDE1,MAP3K5,DOCK9,MFSD3,S100A11,IQGAP1,RALBP1,RNF182,MGST2,DDR1,ZNF385B,CDS1,CCND1,MUC16,SCNN1A,MYT1,SCN3A,MYO5B,MX1,SEC23A,FOXJ2,DRAP1,SYNE2,UTRN,DNAJB14,PYGO1,ATP10D,NIN,PRDM11,JAK1,PDLIM3,SHROOM3,WFS1,INPP4B,TRIOBP,ZNF704,NRG1,NR3C2,COBL,PDIA3,EFHD2,SEPP1,NEO1,SLC25A36,WWP2,SNTA1,FUT2,ANKS1B,CTSC,PTEN,FAM20B,ATP8B1,SLC44A2,WWP1,NCOA2,RASGRF1,PDGFC,PLSCR1,FAM160A1,FMN1,RAPGEF2,MFSD2B,PIK3R1,CXorf57,AK4,DIAPH2,YES1,GRTP1,ARSK,RPL12,MAMDC4,PLOD2,RAB11FIP2,ABCB1,ARSB,USF2,CXorf56,OCLN,TLL2,EXPH5,LTBP1,LMCD1,VARS2,MPP5,ITPR2,PDGFB,DNER,KREMEN1,TMC1,DENND2D,PLS3,NKAIN3,ARHGEF10L,SIPA1L2,ARHGEF37,SHC3,NPNT,IMPAD1,ANKFN1,SLC44A1,DLG1,DUSP10,RP2,MYH14,ANO4,MYRIP,BTBD3,RASGRP1,ZNF462,MCTP1,CELSR2,NFE2L1,RGAG1,ANLN,IDH1,SESN1,ZBTB7B,PTGFRN,EDNRA,DPYSL3,MDK,MAN2A2,PLCH1,MFAP3L,NEIL1,GPRC5B,KLF12,MAP2,KLF11,EPB41L4A,GLCCI1,PCSK5,PRKAA2,LASP1,BVES,HLA-F,ETV5,SAMD9,CNTNAP2,PHLPP1,IL18R1,ANO1,FRAS1,MDFIC,LIMCH1,PIM1,ALS2CL,MDFI,CHSY3,RGMB,PDE5A,HMG20B,EIF2AK1,ANKRD29,AMDHD1,SOX13,RASGRP2,UTP14C,ALPK3,CTSA,LTBP2,PLD1,SEMA3A,COL16A1,NIPA1,USP43,KLF7,NCKAP5,NF2,FOXM1,TMX4,TP53,TDRKH,OSR2,STIL,CYP4F11,FRYL,N4BP3,RPN2,EGLN3,F2R,MBP,ERBB2IP,DOCK5,TAPBP,BFSP1,PTK7,ADAMTS14,TLE1,EFNA5,SPTBN5,IRF7,CYP2U1,SYT13,LIFR,NDST3,TSPAN15,POC1B,GABRG2,SELL,COL4A5,NRP2,PPP2R3A,CD109,FOXP2,IRF2BPL,MDM1,BMP7,GALNS,GTF2F2,ARVCF,ALDH7A1,CLIP2,TLE6,HMMR,DLGAP1,SUN2,FBLN5,RAB3B,AMFR,ASPM,RC3H2,OGDHL,MAML2,COL7A1,PELI3,BBS2,TXNDC11,PRDX4,ARHGAP24,ENDOD1,FAT4,SERPINA1,TMC5,CDCA7L,PGRMC1,FAM117A,UACA,ARRB1,CLIP4,SH3BGRL2,GRAMD1C,SOX8,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1 |
| 4.479e-03 | -5.41 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_DN | 192 | 31 | 17758 | 1761 |
MX1,B3GNT2,FAM169A,IL15RA,LGALS3,NUB1,ARFRP1,CD274,ALCAM,LGALS3BP,EFR3A,MAP2,NR1D2,RND3,FRYL,WFS1,NFKBIA,ELF5,CST3,FUT8,TFAP2A,RAB20,CD70,NFKBIZ,KLK7,ECE1,PIM1,TSPAN1,MYLIP,TIPARP,C9orf72 |
| 4.479e-03 | -5.41 | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | 192 | 31 | 17758 | 1761 |
SPRED1,PSMB4,NFKBIE,NLRX1,ATP9A,SH3BGRL,CD82,FLYWCH2,RASSF7,PBX3,NEURL1B,BORA,CMTM6,CHPF,DHX32,DGKH,PIK3AP1,DPYSL2,TMEM30A,AIM1,BAX,DRAM1,HDAC1,EGFL7,NR4A2,PPP2R3C,MINPP1,NDE1,SERPINB1,C9orf72,RARG |
| 4.479e-03 | -5.41 | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | 192 | 31 | 17758 | 1761 |
LGALS3,PLSCR1,IQGAP1,DNAJC3,TAP1,PPFIBP2,PDIA5,ASAH1,COL18A1,IL18,GDF15,OAT,MERTK,FAM46C,STX3,CMTM7,GLCE,GNS,AMZ2,B3GALNT1,TYMP,NUCB1,CD9,CD70,RPN2,ECE1,ATP1B3,TMEM159,NDUFA12,C9orf72,CKAP4 |
| 4.479e-03 | -5.41 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | 192 | 31 | 17758 | 1761 |
GRN,MAP3K3,SUN2,ORAI2,HECA,BMF,TRIM8,PINK1,TACC1,RPS6KA1,EFHD2,TTC7A,RUNX3,IL27RA,ADRBK2,FUCA1,NCOA3,CXCL16,PIK3AP1,PVRL2,WDR44,STK38,MGAT4A,SGK3,SORL1,ZDHHC7,ARRB1,LTBP2,PIK3CD,SYK,CTDSP2 |
| 4.479e-03 | -5.41 | GSE17721_CTRL_VS_LPS_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDM_DN | 192 | 31 | 17758 | 1761 |
MYO5B,PPIF,RAB3B,UGT8,PLSCR1,NR3C1,CD40,DENND2D,CASP4,APPBP2,EPN3,ENPP1,BTG3,ARTN,CSF1,KBTBD2,LMO4,MMP17,GALNS,NFKBIA,PRKCDBP,SNX16,FHL1,CACNA1D,FZD5,PTPRE,ST3GAL1,IFIH1,PPP2R2D,RARG,FGD1 |
| 4.479e-03 | -5.41 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | 192 | 31 | 17758 | 1761 |
PRSS23,RGMB,MPP1,PBK,RAPGEF2,PTPN9,HEXB,CDCA8,NRG2,DHRS3,RANBP9,SH2D4A,NIN,TMEM63A,IRS2,KIF5B,FUT2,PIK3AP1,TMEM30A,SLC2A6,SGK3,STEAP2,FAM63A,ABCD1,GLB1L2,MLKL,CENPE,TMEM120A,CPEB2,E2F8,ARHGEF4 |
| 4.479e-03 | -5.41 | GSE5960_TH1_VS_ANERGIC_TH1_DN | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_DN | 192 | 31 | 17758 | 1761 |
BIN1,SERPINE2,CHCHD7,GNPDA1,NFE2L1,F11R,PDK3,PRKACA,REPS1,CYB5A,GABARAPL1,PLS3,IER3,AMZ2,MDK,ATP6V0B,RBL1,SCG2,CORO1C,SLC44A1,PAPSS1,NR4A3,RPN2,ITGAV,PHKA2,F2RL1,NRGN,TOB1,CAPN1,ACOT7,ABCC1 |
| 4.479e-03 | -5.41 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 192 | 31 | 17758 | 1761 |
FADS2,HECA,ITGA6,CUL4B,PIK3R1,MBNL3,PTGER4,ASAH1,TESK2,DUSP4,PHLDA1,CMTM7,CD83,FAM111A,ATP1A1,FAM46A,ANKRD6,PTER,ITPR1,FAM83D,ABCB1,PGM2L1,TSPAN13,STK39,RELL1,PACSIN1,NCAPG2,TBC1D4,C12orf75,SOCS5,METAP2 |
| 4.479e-03 | -5.41 | GSE17721_CTRL_VS_LPS_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_8H_BMDM_DN | 192 | 31 | 17758 | 1761 |
CPD,PMPCB,RHOA,RUNX2,GRHL2,KLHL13,NR4A1,MPP1,CD82,FURIN,PDIA5,EFHD2,BCL2L1,CARD10,PSMA4,SPTB,ARF4,ARHGAP35,PVRL2,NFKBIA,AMMECR1,ITPR1,HDAC1,MDFIC,SERPINI1,MAP3K5,PTPRE,TRAF5,MYT1,PPP2R2D,JARID2 |
| 4.479e-03 | -5.41 | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | MSigDB lists | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | 192 | 31 | 17758 | 1761 |
SCN5A,LASP1,PARP12,BTNL9,COQ10B,LPGAT1,DGKQ,ERI2,PBX3,ERBB2IP,DUSP4,SESN1,CDK5R1,FRMD4B,CD83,NFIX,C16orf74,KIF5B,PTPRJ,SESN3,GRHL1,RBL1,SLC44A1,ANKRD12,TMBIM6,CD70,GLCCI1,MYLIP,TOB1,RARG,HIPK3 |
| 4.479e-03 | -5.41 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | 192 | 31 | 17758 | 1761 |
SIGIRR,SMARCA2,SLC35D2,COL6A2,ENO2,IFITM3,TESK1,HMG20B,EFHD2,PRKCQ,IL27RA,NUCB2,PKN1,DENND2D,LTBP3,OPTN,ATP13A2,PSMD1,UAP1,LRIG1,INPP4B,PLEKHF1,FAM102A,STK39,CABIN1,CTSA,CITED2,NDFIP1,MYBL1,NRBP1,MPHOSPH9 |
| 4.479e-03 | -5.41 | GSE3982_NKCELL_VS_TH2_DN | MSigDB lists | GSE3982_NKCELL_VS_TH2_DN | 192 | 31 | 17758 | 1761 |
PLA2G4A,NFE2L3,CENPA,SEC61B,KIF20A,EPAS1,CKAP2,CENPI,PTTG1,ABCG2,EZR,NUSAP1,DUSP4,GTF2A2,KIF11,STIL,FANCI,FRMD4B,TNS3,SLCO4A1,PRPS2,INPP4B,AURKA,TSPAN13,MANF,NCAPG2,TBC1D4,CCNB2,ESPL1,ACOT7,CKS2 |
| 4.486e-03 | -5.41 | GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | GTPASE_ACTIVATOR_ACTIVITY | 59 | 13 | 17758 | 1761 |
ARHGEF10L,DOCK4,ARAP3,RGS3,RAPGEF2,RALBP1,RASA2,RGS20,ARFGEF1,RGS14,RAP1GAP,RASA1,ABR |
| 4.486e-03 | -5.41 | chr12q23 | MSigDB lists | chr12q23 | 59 | 13 | 17758 | 1761 |
CDK17,ELK3,ANKS1B,NUAK1,DEPDC4,GNPTAB,DRAM1,FGD6,ANO4,C12orf75,AMDHD1,CKAP4,CCDC38 |
| 4.490e-03 | -5.41 | PID_RHOA_REG_PATHWAY | MSigDB lists | PID_RHOA_REG_PATHWAY | 46 | 11 | 17758 | 1761 |
ARHGEF10L,PLEKHG6,ARHGEF3,ARAP3,RHOA,ARHGEF11,CDKN1B,ARHGDIB,ABR,DEF6,ARHGAP35 |
| 4.490e-03 | -5.41 | MODULE_259 | MSigDB lists | MODULE_259 | 46 | 11 | 17758 | 1761 |
FGFR2,PTK7,AXL,EPHA4,DAPK1,ERBB2,IL13RA1,ROR1,MERTK,LEPR,CDK5R1 |
| 4.490e-03 | -5.41 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | 46 | 11 | 17758 | 1761 |
SLC35D2,PPP1R2,LYRM1,TMX4,PARP4,PBX3,TGOLN2,GTF3A,GLO1,CBX7,JARID2 |
| 4.490e-03 | -5.41 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | 46 | 11 | 17758 | 1761 |
SUN1,ING1,EFR3A,HLA-F,BCL6,ARFRP1,RAB6A,NPC2,DGKG,CDKN2D,CTDSP2 |
| 4.490e-03 | -5.41 | PID_SYNDECAN_1_PATHWAY | MSigDB lists | PID_SYNDECAN_1_PATHWAY | 46 | 11 | 17758 | 1761 |
COL9A3,COL6A2,HPSE,COL13A1,COL6A1,COL7A1,COL4A5,SDC1,PRKACA,COL16A1,COL12A1 |
| 4.506e-03 | -5.40 | HOLI | smart domains | SM00430 | 48 | 12 | 9131 | 997 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 4.511e-03 | -5.40 | G13 Signaling Pathway | WikiPathways | WP524 | 40 | 11 | 4455 | 516 |
CALM2,RHOA,CIT,IQGAP1,LIMK1,CALM1,PIK3CA,CALM3,ARHGDIB,PIK3CD,PKN1 |
| 4.516e-03 | -5.40 | V$STAT5A_04 | MSigDB lists | V$STAT5A_04 | 200 | 32 | 17758 | 1761 |
RUNX2,ARFGEF1,FAM81A,ETS1,TNFRSF19,ZNF385B,SYTL2,MECOM,PLS3,FRY,ANKS1B,PHTF1,MITF,DIXDC1,NCAM1,CITED2,TRIM62,CAPN6,BCL9,PBK,NR4A1,LDB2,AIF1L,PITX2,CXXC4,SCG2,ITPR1,ABCB1,ARPC2,NDFIP1,AFAP1,HOXC13 |
| 4.521e-03 | -5.40 | V$ETS_Q4 | MSigDB lists | V$ETS_Q4 | 240 | 37 | 17758 | 1761 |
SIGIRR,CAST,ETV5,NDUFA4,TRMT2B,ITPR2,PKN1,PDGFB,CMTM6,TEAD3,ZNF687,RINL,RGS3,MGAT4A,FXYD5,POF1B,TWIST1,DAB2IP,ACSL4,SCN2A,PLCB2,SCN3A,RBMS2,ELK3,FURIN,PPP1R14C,SPNS3,EPN3,KLF12,FGFR2,ITPR1,RAP2C,MADD,HMGA1,DRP2,RGS14,ARSB |
| 4.523e-03 | -5.40 | Oncostatin M Signaling Pathway | WikiPathways | WP2374 | 63 | 15 | 4455 | 516 |
PIAS3,CASP3,TIMP3,AKT1,JAK1,CYR61,IL6ST,NFKBIA,PIK3R1,TP53,CDKN1B,JAK3,FOS,LIFR,SOCS3 |
| 4.525e-03 | -5.40 | TTGGAGA,MIR-515-5P,MIR-519E | MSigDB lists | TTGGAGA,MIR-515-5P,MIR-519E | 138 | 24 | 17758 | 1761 |
ARHGEF3,MOSPD2,TACC1,IQGAP1,PM20D2,ETS1,NFIB,CMTM6,SP4,NCS1,SLC9A2,SGPL1,UBE2Q2,SLC4A4,CYR61,FGFR2,FRAS1,OSBPL3,CSNK1G1,RAP2C,CAB39,DONSON,CLIP2,CPEB2 |
| 4.539e-03 | -5.40 | ACTGCCT,MIR-34B | MSigDB lists | ACTGCCT,MIR-34B | 208 | 33 | 17758 | 1761 |
TRIM2,FRMD4A,DCAF7,CACNA2D2,ETS1,TMCC3,ARHGEF10L,SNTA1,RALGPS2,ANKS1B,STIM1,MITF,ANKRD12,MYRIP,ABCC1,THRB,TESK1,CAPN6,FOXJ2,VEZT,ALCAM,COL12A1,GLCE,NFIX,MAN2A2,CNTNAP1,KLF12,PPP2R5A,PTK7,STK39,NR4A2,NRG1,ATP1B3 |
| 4.552e-03 | -5.39 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 161 | 27 | 17758 | 1761 |
CCDC110,RASA2,CALM1,SELL,CALM3,TCF7,PKMYT1,SNN,TRIB2,MERTK,SCML1,ZDHHC21,CALM2,SESN3,ATP1A1,CDH1,NGFRAP1,METTL7A,IL6ST,KLF3,WWP1,SLC39A10,LGMN,GLCCI1,ALS2CL,KLF7,ABCC1 |
| 4.552e-03 | -5.39 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 161 | 27 | 17758 | 1761 |
SMARCA2,TGIF1,PDGFC,SERPINE2,CAPN6,SEPT6,SYNE2,HMGN3,DUSP4,SNN,CRABP2,LDB2,NEO1,PLS3,MDK,PITX2,RCN1,SLC25A4,PLOD2,TSPAN6,PLK2,FLRT3,DLG3,SEMA3A,SLC12A2,MGAT5,AFAP1 |
| 4.565e-03 | -5.39 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | 466 | 64 | 17758 | 1761 |
S100A11,PSME2,PTTG1,NDC80,TP53,RGS20,IL27RA,NENF,GRK6,MORF4L2,STIM1,DPYSL2,CTTN,TECR,PHKA2,GPX4,CKS2,CDC20,SERTAD3,NFE2L1,EZR,CR2,ARHGDIB,ICMT,CCNF,H2AFV,ATP1A1,KCNK1,PNPLA6,HDAC1,RGS14,HSPB1,MAPK12,ALDH6A1,PEX6,CENPI,ETV5,AES,COX6C,PKN1,WWP2,SGPL1,TOP2A,DAZAP1,RPL39,CST3,BAX,GTF2F2,ATP8B1,AHCY,CD70,CNPY3,DDB2,HES1,ZNF84,KIF20A,TESK1,TCF7,DBI,SLC2A6,AURKA,UBE2C,AHR,ACOT7 |
| 4.568e-03 | -5.39 | ROESSLER_LIVER_CANCER_METASTASIS_UP | MSigDB lists | ROESSLER_LIVER_CANCER_METASTASIS_UP | 101 | 19 | 17758 | 1761 |
HMMR,ENO2,GCLC,RGS20,COL4A5,TGOLN2,YES1,MAP3K6,CDS1,PITX2,ALDH3B1,NR1D2,LIMK1,FUT8,IRF2,SERPINB6,HOXB13,CENPE,MDFI |
| 4.568e-03 | -5.39 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | 101 | 19 | 17758 | 1761 |
PSME2,USP18,TAP1,LITAF,PSME1,IFIT3,RNF19B,IL18R1,LGALS3BP,FAS,TAPBP,IL6ST,AIM1,NFKBIA,NFKBIZ,IRF7,IFIT1,SNX10,XDH |
| 4.568e-03 | -5.39 | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP | MSigDB lists | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP | 101 | 19 | 17758 | 1761 |
CENPA,KIF20A,CELSR2,PLSCR1,SLC39A8,SYBU,PRIM1,NKAIN3,NCOA3,RNF128,CTSC,MATN2,ALDH1A3,ABCA2,HS3ST3B1,TMEM159,NCAM1,CCNB2,RRAGD |
| 4.568e-03 | -5.39 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 101 | 19 | 17758 | 1761 |
PGM1,ENO2,ZNF395,S100A4,PLAUR,SOX9,AK4,LOXL2,PDGFB,FOS,CYB5A,DPYSL2,P4HA2,ITPR1,LIMCH1,EGLN3,CITED2,RRAGD,EGLN1 |
| 4.576e-03 | -5.39 | placenta development | biological process | GO:0001890 | 142 | 25 | 16441 | 1675 |
HES1,GRHL2,CDKN1C,AKT1,EPAS1,ST14,CCNF,PDGFB,SOCS3,E2F7,NCOA3,HS6ST1,DAZAP1,ITGB8,CYR61,FGFR2,GATA2,CTSV,SPINT2,PLK4,FZD5,GAB1,E2F8,MDFI,EGLN1 |
| 4.577e-03 | -5.39 | mandible | COSMIC cancer mutations | mandible | 28 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PIK3CA,TP53,ERBB2,JAK3,IDH1 |
| 4.579e-03 | -5.39 | Mapk1 (mitogen-activated protein kinase 1) | protein interactions | 26413 | 4 | 3 | 16036 | 1726 |
KLF11,BCL2L1,TP53 |
| 4.579e-03 | -5.39 | DNAJC16 (DnaJ (Hsp40) homolog, subfamily C, member 16) | protein interactions | 23341 | 4 | 3 | 16036 | 1726 |
HLA-C,TMEM30A,SPINT2 |
| 4.579e-03 | -5.39 | Tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 24811 | 4 | 3 | 16036 | 1726 |
PDIA3,HLA-B,HLA-A |
| 4.579e-03 | -5.39 | HLA-H (major histocompatibility complex, class I, H (pseudogene)) | protein interactions | 3136 | 4 | 3 | 16036 | 1726 |
HLA-B,HLA-C,HLA-E |
| 4.579e-03 | -5.39 | BTN1A1 (butyrophilin, subfamily 1, member A1) | protein interactions | 696 | 4 | 3 | 16036 | 1726 |
PLK1,TRIM68,XDH |
| 4.579e-03 | -5.39 | DRP2 (dystrophin related protein 2) | protein interactions | 1821 | 4 | 3 | 16036 | 1726 |
DAG1,PRX,UTRN |
| 4.579e-03 | -5.39 | KIF6 (kinesin family member 6) | protein interactions | 221458 | 4 | 3 | 16036 | 1726 |
SNX16,HEATR5A,APPBP2 |
| 4.587e-03 | -5.38 | catabolic process | biological process | GO:0009056 | 1809 | 217 | 16441 | 1675 |
CASP3,GAA,HSPG2,AASS,CRYM,GNPDA1,CPT2,CNOT8,DNAJC3,CUL4B,HEXB,LMCD1,FBXO2,PSME1,CCNB1,OAT,HDAC6,SDC1,CALM2,TYMP,CYP1A1,PSMD1,ZFP36,CYP2S1,PIK3CA,FUT1,TINAGL1,ACOX2,APOBEC3G,ERAP2,CYP1B1,PLK1,FBXL16,SPATA18,ITCH,USP18,CDA,SLC35C1,AGO4,KLK6,CCNF,RNF19B,CYP4F3,CDK1,POR,COL12A1,TRIM9,PLCH1,ENPP1,PLCG1,NEIL1,HPSE,WIPI1,PTER,DHTKD1,GLA,CAPN1,NR2C2,MRC2,ALDH6A1,DNAJB2,CALM3,SLC1A3,ATG4A,GNS,RIMS3,RPL39,COL6A1,FAM13B,BDH1,NEK2,PCYOX1,PRKG1,AHCY,ALPK1,ZRANB1,NCEH1,MYLIP,PLCB2,GAD1,MCCC2,CYP26B1,PRODH,CALM1,PYM1,PDE5A,TP53INP2,PSMA4,AMDHD1,DCP2,MMP15,NUDT16,H1F0,FAAH,COL13A1,AURKA,MDH1,YOD1,CTSA,PLD1,COL16A1,RNF146,XDH,USP43,PLA2G4A,UPF3B,PSME2,PTTG1,COL18A1,MVB12B,LPIN3,PRKACA,CYP39A1,CYP26A1,RAD23A,CYP4F11,KIF14,PLCG2,FABP6,DAB2IP,GOT1,ECE1,PDE4D,PHKA2,LGMN,NAGA,GM2A,CHP1,ATG4D,CTH,SIRT1,ENPP4,SEC61B,ERLEC1,COL6A2,AKT1,SAT1,CDC20,ATP1B1,GABARAPL1,DNAJC10,DUOX1,ALDH3B1,ALDH5A1,IDE,ABHD12,WFS1,PEX2,PNPLA6,ADAMTS14,PRIMA1,CYP2U1,LTA4H,COL9A3,PINK1,ENO2,CIT,HAL,BLVRB,SDC4,ERI2,PSMD10,CTSZ,COL4A5,APOBEC3H,NOTUM,FBXO6,DNAJB9,WWP2,SGPL1,FUT2,ADORA1,RNF128,CTSC,PTEN,GALNS,FUT8,UBE2J1,ADAM15,ECI2,WWP1,ALDH7A1,ABCD1,CNOT6L,FAH,HMMR,ACBD5,ADAMTS2,PGM1,SHMT1,ALDH2,PSMB4,GUSB,AMFR,NUB1,UBE2A,FURIN,OGDHL,FBXO9,COL7A1,BLVRA,RNPEP,FUCA1,CTSL,RPL12,ACADSB,PLOD2,CTSV,ARRB1,PGM2L1,ERAP1,ARSB,NDFIP1,WDR45B,UBE2C,ACOT7,DIS3L |
| 4.593e-03 | -5.38 | cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular function | GO:0004861 | 12 | 5 | 16491 | 1673 |
CDKN1B,CDKN2C,CASP3,CDKN1C,CDKN2D |
| 4.593e-03 | -5.38 | intronic transcription regulatory region DNA binding | molecular function | GO:0044213 | 12 | 5 | 16491 | 1673 |
HSF2,GRHL2,THRA,NCOA2,BCL6 |
| 4.598e-03 | -5.38 | regulation of protein binding | biological process | GO:0043393 | 157 | 27 | 16441 | 1675 |
PLK1,EPB41L5,CTHRC1,NKX3-1,ADD1,AMFR,RAPGEF2,PPARA,TGFBR1,AES,PRKACA,PDGFB,CTNNBIP1,PTPRF,APLP2,PLK2,BAX,AURKA,SORL1,ARRB1,TMBIM6,ADAM15,DAB2IP,NRG1,IFIT1,WNT3A,TMEM173 |
| 4.598e-03 | -5.38 | regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001236 | 157 | 27 | 16441 | 1675 |
GCLM,LGALS3,AKT1,ITGA6,GCLC,RET,PDIA3,STRADB,TGFBR1,BCL2L1,PELI3,GSTP1,LMNA,FAS,SP100,SCG2,MADD,DAPK1,BAX,TNFRSF12A,NRG1,ITGAV,GPER1,CTTN,UNC5B,FAIM,IFI6 |
| 4.600e-03 | -5.38 | PLAUR (plasminogen activator, urokinase receptor) | protein interactions | 5329 | 107 | 21 | 16036 | 1726 |
CHSY3,GCLM,MGAT4B,GYLTL1B,LOXL2,PKN1,ARSK,SRPX2,DNAJB9,MAN2A2,JAK1,IL6ST,GALNS,PCYOX1,EGFL7,CTSA,CTTN,ARSB,MGAT5,MELK,PCSK5 |
| 4.603e-03 | -5.38 | NDC80 (NDC80 kinetochore complex component) | protein interactions | 10403 | 61 | 14 | 16036 | 1726 |
AMOTL2,PLK1,ZWINT,SPC25,TNIP1,NDC80,NEK2,KLC3,AURKA,CCDC68,NUF2,BUB1,CCNB1,NDE1 |
| 4.612e-03 | -5.38 | Protein processing in endoplasmic reticulum | KEGG pathways | ko04141 | 168 | 30 | 6908 | 758 |
SEC23A,ERLEC1,SEC61B,AMFR,DNAJC3,DNAJB2,ERO1A,FBXO2,PDIA3,DNAJB11,EIF2AK1,FBXO6,ERP29,BCAP31,RAD23A,PDIA4,DNAJC10,DDOST,WFS1,RRBP1,BAX,UBE2J1,RPN2,YOD1,MAP3K5,LMAN1,PDIA6,TRAM1,CKAP4,CAPN1 |
| 4.612e-03 | -5.38 | Protein processing in endoplasmic reticulum | KEGG pathways | hsa04141 | 168 | 30 | 6908 | 758 |
SEC23A,ERLEC1,SEC61B,AMFR,DNAJC3,DNAJB2,ERO1A,FBXO2,PDIA3,DNAJB11,EIF2AK1,FBXO6,ERP29,BCAP31,RAD23A,PDIA4,DNAJC10,DDOST,WFS1,RRBP1,BAX,UBE2J1,RPN2,YOD1,MAP3K5,LMAN1,PDIA6,TRAM1,CKAP4,CAPN1 |
| 4.627e-03 | -5.38 | Gastrin-CREB signalling pathway via PKC and MAPK | REACTOME pathways | R-HSA-881907 | 424 | 62 | 8202 | 867 |
SPRED1,PSME2,RPS6KA1,IQGAP1,RASA2,DGKQ,PSMD10,ERBB2,NRG2,CALM3,PSME1,ITPR2,PDGFB,SPTB,FGF19,GRM5,CALM2,PDGFA,PSMD1,RPS6KA2,ADRBK1,GNB5,SHC3,PIK3CA,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,DGKG,F2R,PLCB2,RASGRP1,FRS3,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,PRKCQ,DUSP4,ITPR3,GNA11,PSMA4,DGKE,RASA1,RASGRP2,EDNRA,DGKH,IRS2,PPP2R5A,JAK1,ABHD12,FGFR2,ITPR1,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,F2RL1 |
| 4.628e-03 | -5.38 | TRAF6 (TNF receptor-associated factor 6, E3 ubiquitin protein ligase) | protein interactions | 7189 | 252 | 41 | 16036 | 1726 |
SIGIRR,PINK1,NLRX1,TGFBR1,TNFRSF19,IL17RB,PSMD1,PPP4R1,WWP1,LGMN,ZRANB1,TRAM1,SYK,MAP3K3,MBP,RIPK2,AKT1,ITCH,PLEKHO1,STRADB,PELI3,YES1,IFIT3,CD40,ZFAND5,RANBP9,CASP4,SOCS3,NGFRAP1,UEVLD,CSNK1G1,PELI2,TRAF3IP1,NOD2,ARRB1,OTUB2,IRF7,MAP3K5,TRAF5,RUSC1,NR2C2 |
| 4.631e-03 | -5.37 | skeletal system development | biological process | GO:0001501 | 471 | 66 | 16441 | 1675 |
PAPSS2,GRHL2,HSPG2,HOXB7,THRA,HEXB,OSR2,FAM101B,PLS3,PDGFA,NOV,CTGF,IMPAD1,PAPSS1,DLG1,TWIST1,TIPARP,SP5,SULF2,SPEF2,PTGER4,PRKRA,ZFAND5,COL12A1,HOXA9,BMP1,PCSK5,RUNX2,CDKN1C,LGALS3,HAPLN3,SOX9,RAB23,TGFBR1,DHRS3,HOXB2,SIX4,SGPL1,ITGB8,CYR61,BMP7,MEGF8,TFAP2A,MDFI,CYP26B1,PDGFC,RHOA,FMN1,AMER1,ANO6,RUNX3,BBS2,GNA11,NFIB,GPLD1,PITX2,GNAS,ETS2,FAT4,SEMA4D,FGFR2,COL13A1,LRRK1,GDF11,OSR1,RARG |
| 4.637e-03 | -5.37 | response to mineralocorticoid | biological process | GO:0051385 | 33 | 9 | 16441 | 1675 |
CALM2,CCND1,CTGF,CALM1,FOSB,BAX,CALM3,GPER1,FOS |
| 4.637e-03 | -5.37 | salivary gland development | biological process | GO:0007431 | 33 | 9 | 16441 | 1675 |
NKX3-1,TWSG1,FGFR2,BMP7,CST3,PLXNA1,SEMA3A,NFIB,DAG1 |
| 4.652e-03 | -5.37 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4562 | 497 | 17775 | 1757 |
LAMP1,SLC35D2,ACACB,GAA,PPP4R4,KLK10,SSH1,HSPG2,AK7,SLC25A13,ATP8A1,DNAJC3,CACNA2D2,PPFIBP2,DHX8,NRG2,ISOC2,DPP8,FAM101B,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,DAPK2,AP1M2,MUC4,ELMO2,RGS3,IQCE,PRICKLE3,KCNS3,PIK3CA,ATRNL1,MTMR11,MANF,MARCH2,TIAM1,NWD1,SGCE,LOC81691,FBXL16,SPATA18,SNTB2,SH3BGRL,TMEM151A,TFAP2C,PRKAR2B,TNS1,KIF13A,LOXL2,GALNT7,LDB2,CCNF,TP53I3,COL12A1,PRIM1,AHRR,PGF,PLCG1,RBM47,DNM1L,GDE1,ATP7B,GNPTAB,NKD1,FAM114A1,PRDM5,BMP1,NFKBIZ,UNC5B,WBSCR27,E2F8,FGD1,SCN5A,CDK17,NFKBIE,SOX9,CALB2,SLC1A3,GPSM2,TSPAN7,TTYH3,PSIP1,MECOM,ELF3,GNS,DOPEY2,FRY,ITGA3,FAM189A1,VASN,MEGF8,AIM1,RUNDC3B,PRKG1,TPST1,SORL1,CD70,CADPS2,ALPK1,CACNA1D,PANX2,NCAM1,DGKG,SYTL3,C9orf72,RIMS2,GPR161,PAQR7,IGSF3,TRAK2,EPB41L5,GFPT1,PMPCB,B3GNT7,MFI2,MMD,ZNF84,KIF20A,ADCK3,STAT4,AMER1,ATP8B3,NPHP3,SPTLC2,ANTXR1,GNA11,RASA1,DHX32,CACHD1,NCOA3,PLEKHH2,ETS2,TIMM8A,ITPR1,FGD6,CLMN,PCDH19,CABIN1,DRP2,MAP3K5,PER3,XDH,ADAMTS16,DOCK9,PLA2G4A,FRMPD3,CEP70,ARMCX3,TRIP10,ST14,ACTR8,ATP2C2,RGS20,IL13RA1,ZNF385B,CDS1,CCND1,APLP2,MUC16,ST5,ACAP2,SCNN1A,CDH1,SP100,TRANK1,DACT1,XYLT2,CDKN1B,RASGEF1A,SNX10,MYT1,SCN3A,MYO5B,DOCK4,ENPP4,CAMSAP3,SEC23A,COL6A2,COG2,SEPT6,SYNE2,UTRN,KIF1C,NUSAP1,ITPR3,ALCAM,SP4,ZNF469,NIN,EPHA10,DDOST,PDLIM3,JAK1,SHROOM3,AXL,SIPA1L1,PLEKHG1,PNPLA6,NRG1,NR3C2,COBL,TTC8,TNRC6C,CKAP2,ATP9A,EPS8,SDC4,CCNJL,PDIA3,HERC5,PBX3,CTSZ,PKN1,PLPPR4,DNAH3,HOXB2,NEO1,ANKS1B,PTEN,FJX1,TMBIM6,SLC44A2,WWP1,ERBB3,NPTXR,TRIM62,SLC16A5,CRTAP,PARP9,FARP2,ADAMTS2,RASGRF1,PDGFC,ZWINT,ARAP2,LONRF3,ZC3H11A,RAPGEF2,MPP1,PIK3R1,MRS2,ZKSCAN2,MYEOV,DIAPH2,C2orf69,SNTB1,CRISPLD2,CNTNAP1,ACADSB,PLOD2,FGFR2,RAB11FIP2,TBX18,ABCB1,ITGAV,FHL1,WDR62,ARSB,USF2,ESPL1,CXorf56,DCBLD1,ACOT7,DEF6,OCLN,TLL2,TMEM131,ESYT2,RGMA,EXPH5,LTBP1,SIGIRR,TRIM2,EPAS1,FHDC1,ARFGEF1,TEX2,NENF,F11R,HDAC6,NUP62CL,DNER,CACNB4,TRIM68,SPTB,DENND2D,PLS3,ZFYVE16,BTG3,SIPA1L2,CPNE2,LRRC6,SHC3,MKRN3,PAPSS1,ANKFN1,DLG1,ABCA2,DUSP10,RP2,TLN2,PTPRE,MYRIP,MYBL1,TRAM1,NEB,CELSR2,STAU2,ITCH,NFE2L1,EZR,KLK6,ARHGDIB,ANLN,PTGFRN,EDNRA,HS6ST1,MAP2,DOLPP1,MADD,PIK3C2B,PIEZO1,EPB41L4A,NR2C2,GRN,PPP1R2,ZNF395,BVES,RASA2,CNTNAP2,SAMD9,PM20D2,ADAMTSL4,ANO1,B4GALNT1,UBE2Q2,IGF1R,SPIN4,FRAS1,COL6A1,FXYD5,LIMCH1,PIM1,ZRANB1,LRIF1,GAD1,SLC12A2,PLCB2,ALS2CL,ABCC1,DPYSL5,CHSY3,MRPS33,TESK1,ZNF320,MGAT4B,GYLTL1B,VWA1,HMG20B,PDE5A,HEATR5A,NUBP1,ANKRD29,AMDHD1,SOX13,UAP1,COL13A1,TMEM30A,CSF1,MFSD2A,PHLPP2,P4HA3,NLRC5,ALPK3,RHOBTB2,CTSA,LTBP2,PLD1,ZDBF2,SHROOM2,SEMA3A,JAK3,COL16A1,PROM2,NCKAP5,SLC25A24,NF2,UGP2,CTDSPL,TMX4,XYLT1,PDIA5,TP53,COL18A1,ERBB2,IL27RA,TDRKH,LPIN3,KBTBD11,ARHGEF16,SYTL2,TTC21B,ZNF687,EFR3A,WDR44,KIF14,PLK4,ZDHHC23,ESPN,RPN2,EPB41L4B,NOTCH3,OAS3,MINPP1,LMAN1,SCN2A,F2R,CTH,CPD,AKT1,PTPRU,SLC39A8,COQ10B,IGSF8,DOCK5,SOCS3,ARHGAP35,PTPRJ,RBL1,ABHD12,PTK7,BHLHB9,ADAMTS14,VSIG10,ANXA9,ABCA1,NDST3,LNP1,LIFR,GLIS3,COL9A3,CDH22,CPEB4,ARHGEF11,FRMD6,MIER3,TGFBR1,COL4A5,NKRF,AES,TRMT2B,INTS8,TRIB2,PPP2R3A,NRP2,CD109,FOXP2,TAF1B,ALPP,LLGL2,BMP7,TOX2,ARVCF,ABCD1,BUB1,IQGAP3,ATP2B1,FAH,IGDCC4,NFE2L3,DLGAP1,RHOA,GUSB,NR3C1,DEPDC4,PRICKLE1,GGH,COL7A1,FNDC3A,RNPEP,TXNDC11,LEPR,FUCA1,ENDOD1,BANK1,FAT4,C2orf70,RND3,FAM117A,ICOSLG,TBC1D4,ARHGEF9,AHR,PKIA,ARHGEF4 |
| 4.652e-03 | -5.37 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4562 | 497 | 17775 | 1757 |
LAMP1,SLC35D2,ACACB,GAA,PPP4R4,KLK10,SSH1,HSPG2,AK7,SLC25A13,ATP8A1,DNAJC3,CACNA2D2,PPFIBP2,DHX8,NRG2,ISOC2,DPP8,FAM101B,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,DAPK2,AP1M2,MUC4,ELMO2,RGS3,IQCE,PRICKLE3,KCNS3,PIK3CA,ATRNL1,MTMR11,MANF,MARCH2,TIAM1,NWD1,SGCE,LOC81691,FBXL16,SPATA18,SNTB2,SH3BGRL,TMEM151A,TFAP2C,PRKAR2B,TNS1,KIF13A,LOXL2,GALNT7,LDB2,CCNF,TP53I3,COL12A1,PRIM1,AHRR,PGF,PLCG1,RBM47,DNM1L,GDE1,ATP7B,GNPTAB,NKD1,FAM114A1,PRDM5,BMP1,NFKBIZ,UNC5B,WBSCR27,E2F8,FGD1,SCN5A,CDK17,NFKBIE,SOX9,CALB2,SLC1A3,GPSM2,TSPAN7,TTYH3,PSIP1,MECOM,ELF3,GNS,DOPEY2,FRY,ITGA3,FAM189A1,VASN,MEGF8,AIM1,RUNDC3B,PRKG1,TPST1,SORL1,CD70,CADPS2,ALPK1,CACNA1D,PANX2,NCAM1,DGKG,SYTL3,C9orf72,RIMS2,GPR161,PAQR7,IGSF3,TRAK2,EPB41L5,GFPT1,PMPCB,B3GNT7,MFI2,MMD,ZNF84,KIF20A,ADCK3,STAT4,AMER1,ATP8B3,NPHP3,SPTLC2,ANTXR1,GNA11,RASA1,DHX32,CACHD1,NCOA3,PLEKHH2,ETS2,TIMM8A,ITPR1,FGD6,CLMN,PCDH19,CABIN1,DRP2,MAP3K5,PER3,XDH,ADAMTS16,DOCK9,PLA2G4A,FRMPD3,CEP70,ARMCX3,TRIP10,ST14,ACTR8,ATP2C2,RGS20,IL13RA1,ZNF385B,CDS1,CCND1,APLP2,MUC16,ST5,ACAP2,SCNN1A,CDH1,SP100,TRANK1,DACT1,XYLT2,CDKN1B,RASGEF1A,SNX10,MYT1,SCN3A,MYO5B,DOCK4,ENPP4,CAMSAP3,SEC23A,COL6A2,COG2,SEPT6,SYNE2,UTRN,KIF1C,NUSAP1,ITPR3,ALCAM,SP4,ZNF469,NIN,EPHA10,DDOST,PDLIM3,JAK1,SHROOM3,AXL,SIPA1L1,PLEKHG1,PNPLA6,NRG1,NR3C2,COBL,TTC8,TNRC6C,CKAP2,ATP9A,EPS8,SDC4,CCNJL,PDIA3,HERC5,PBX3,CTSZ,PKN1,PLPPR4,DNAH3,HOXB2,NEO1,ANKS1B,PTEN,FJX1,TMBIM6,SLC44A2,WWP1,ERBB3,NPTXR,TRIM62,SLC16A5,CRTAP,PARP9,FARP2,ADAMTS2,RASGRF1,PDGFC,ZWINT,ARAP2,LONRF3,ZC3H11A,RAPGEF2,MPP1,PIK3R1,MRS2,ZKSCAN2,MYEOV,DIAPH2,C2orf69,SNTB1,CRISPLD2,CNTNAP1,ACADSB,PLOD2,FGFR2,RAB11FIP2,TBX18,ABCB1,ITGAV,FHL1,WDR62,ARSB,USF2,ESPL1,CXorf56,DCBLD1,ACOT7,DEF6,OCLN,TLL2,TMEM131,ESYT2,RGMA,EXPH5,LTBP1,SIGIRR,TRIM2,EPAS1,FHDC1,ARFGEF1,TEX2,NENF,F11R,HDAC6,NUP62CL,DNER,CACNB4,TRIM68,SPTB,DENND2D,PLS3,ZFYVE16,BTG3,SIPA1L2,CPNE2,LRRC6,SHC3,MKRN3,PAPSS1,ANKFN1,DLG1,ABCA2,DUSP10,RP2,TLN2,PTPRE,MYRIP,MYBL1,TRAM1,NEB,CELSR2,STAU2,ITCH,NFE2L1,EZR,KLK6,ARHGDIB,ANLN,PTGFRN,EDNRA,HS6ST1,MAP2,DOLPP1,MADD,PIK3C2B,PIEZO1,EPB41L4A,NR2C2,GRN,PPP1R2,ZNF395,BVES,RASA2,CNTNAP2,SAMD9,PM20D2,ADAMTSL4,ANO1,B4GALNT1,UBE2Q2,IGF1R,SPIN4,FRAS1,COL6A1,FXYD5,LIMCH1,PIM1,ZRANB1,LRIF1,GAD1,SLC12A2,PLCB2,ALS2CL,ABCC1,DPYSL5,CHSY3,MRPS33,TESK1,ZNF320,MGAT4B,GYLTL1B,VWA1,HMG20B,PDE5A,HEATR5A,NUBP1,ANKRD29,AMDHD1,SOX13,UAP1,COL13A1,TMEM30A,CSF1,MFSD2A,PHLPP2,P4HA3,NLRC5,ALPK3,RHOBTB2,CTSA,LTBP2,PLD1,ZDBF2,SHROOM2,SEMA3A,JAK3,COL16A1,PROM2,NCKAP5,SLC25A24,NF2,UGP2,CTDSPL,TMX4,XYLT1,PDIA5,TP53,COL18A1,ERBB2,IL27RA,TDRKH,LPIN3,KBTBD11,ARHGEF16,SYTL2,TTC21B,ZNF687,EFR3A,WDR44,KIF14,PLK4,ZDHHC23,ESPN,RPN2,EPB41L4B,NOTCH3,OAS3,MINPP1,LMAN1,SCN2A,F2R,CTH,CPD,AKT1,PTPRU,SLC39A8,COQ10B,IGSF8,DOCK5,SOCS3,ARHGAP35,PTPRJ,RBL1,ABHD12,PTK7,BHLHB9,ADAMTS14,VSIG10,ANXA9,ABCA1,NDST3,LNP1,LIFR,GLIS3,COL9A3,CDH22,CPEB4,ARHGEF11,FRMD6,MIER3,TGFBR1,COL4A5,NKRF,AES,TRMT2B,INTS8,TRIB2,PPP2R3A,NRP2,CD109,FOXP2,TAF1B,ALPP,LLGL2,BMP7,TOX2,ARVCF,ABCD1,BUB1,IQGAP3,ATP2B1,FAH,IGDCC4,NFE2L3,DLGAP1,RHOA,GUSB,NR3C1,DEPDC4,PRICKLE1,GGH,COL7A1,FNDC3A,RNPEP,TXNDC11,LEPR,FUCA1,ENDOD1,BANK1,FAT4,C2orf70,RND3,FAM117A,ICOSLG,TBC1D4,ARHGEF9,AHR,PKIA,ARHGEF4 |
| 4.653e-03 | -5.37 | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | 169 | 28 | 17758 | 1761 |
DDX58,SUN2,KIF20A,IL15RA,HAPLN3,ESRP1,CYS1,TAP1,HERC5,SLC1A3,OSR2,IFIT3,HERC6,DGKE,SOCS3,OTUD1,FAM111A,ITGB8,PIK3AP1,NR4A3,IQCD,SELK,HS3ST3B1,IFIT1,CITED2,IFIH1,SHROOM2,CPEB2 |
| 4.663e-03 | -5.37 | ductolobular_carcinoma | COSMIC cancer mutations | ductolobular_carcinoma | 1676 | 197 | 17775 | 1757 |
HSPG2,HEBP1,TSC22D3,EPHA4,RET,FHDC1,ARFGEF1,PPFIBP2,FAM102B,NDRG2,PLS3,ABCD4,ARHGEF10L,CYP1A1,C7orf49,DPYSL2,MKRN3,PRICKLE3,IL6ST,ANKFN1,PIK3CA,TMEM37,TLN2,TIAM1,DDX59,NEB,RASGRP1,KCNIP3,KIF13A,TNS1,ARFRP1,LOXL2,ROR1,IDH1,SPNS3,TYSND1,RHEB,COL12A1,EDNRA,AHRR,MAN2A2,PLEKHG6,PLCG1,TMEM164,MAP2,BMP1,RAP1GAP,GAB1,PRKAA2,ARAP3,NFKBIE,SERPINE2,GGA1,ZCCHC24,ETV5,MTL5,SAMD9,KIAA1161,RAVER2,ZNF432,DAZAP1,FRY,GATA2,FRAS1,AIM1,RANBP1,SORL1,PANX2,PLCB2,DGKG,PPP6R1,ALS2CL,RIMS2,PRODH,HPS3,TESK1,STAT4,AMER1,RNF113A,ANKRD29,GNA11,DHX32,GNAS,MMP15,FAAH,UTP14C,ITPR1,NFKBIA,SLC4A3,NLRC5,AGBL5,FGD6,ZDHHC7,SHROOM2,HOOK1,SEMA3A,SERPINB1,JAK3,RARG,XDH,ADAMTS16,LMO7,PLA2G4A,ARHGAP11A,AVPI1,SORBS1,NF2,TP53,TESK2,RNF182,APC2,SYTL2,CYP26A1,CDS1,RCN1,ATP6V0B,MUC16,ACAP2,CDH1,EFR3A,KIF14,DACT1,PLCG2,CNNM4,ACSL4,DLG3,SCN2A,SCN3A,SULF2,SUSD3,CLCN3,AKT1,FZD4,PTPRU,CAPN6,SYNE2,SLC11A2,RAB38,MAP3K6,NFIX,IRS2,DUOX1,DNAJC10,JAK1,SIPA1L1,TRIOBP,KLF5,PRIMA1,SLC25A30,NR3C2,ABCA1,LIFR,NDST3,GOLIM4,ERI2,PKN1,DNAH3,HMGXB4,SLC9A2,SIX4,SCML1,CD109,FOXP2,DTX3L,ADD3,ADORA1,IGSF9,PHF7,PTEN,GALNS,SGK3,ATP8B1,CNOT6L,AMOTL2,SUN2,LONRF3,BCL9,AMFR,PIK3R1,ZKSCAN2,TTC7A,COL7A1,BCAR1,DGKE,FUCA1,MAMDC4,FGFR2,DHRS2,ABCB1,ARRB1,GRIN2D,CENPE,ETAA1,ZMIZ1,NCAPG2,ARHGEF4,GOLGB1 |
| 4.663e-03 | -5.37 | breast-carcinoma-ductolobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductolobular_carcinoma | 1676 | 197 | 17775 | 1757 |
HSPG2,HEBP1,TSC22D3,EPHA4,RET,FHDC1,ARFGEF1,PPFIBP2,FAM102B,NDRG2,PLS3,ABCD4,ARHGEF10L,CYP1A1,C7orf49,DPYSL2,MKRN3,PRICKLE3,IL6ST,ANKFN1,PIK3CA,TMEM37,TLN2,TIAM1,DDX59,NEB,RASGRP1,KCNIP3,KIF13A,TNS1,ARFRP1,LOXL2,ROR1,IDH1,SPNS3,TYSND1,RHEB,COL12A1,EDNRA,AHRR,MAN2A2,PLEKHG6,PLCG1,TMEM164,MAP2,BMP1,RAP1GAP,GAB1,PRKAA2,ARAP3,NFKBIE,SERPINE2,GGA1,ZCCHC24,ETV5,MTL5,SAMD9,KIAA1161,RAVER2,ZNF432,DAZAP1,FRY,GATA2,FRAS1,AIM1,RANBP1,SORL1,PANX2,PLCB2,DGKG,PPP6R1,ALS2CL,RIMS2,PRODH,HPS3,TESK1,STAT4,AMER1,RNF113A,ANKRD29,GNA11,DHX32,GNAS,MMP15,FAAH,UTP14C,ITPR1,NFKBIA,SLC4A3,NLRC5,AGBL5,FGD6,ZDHHC7,SHROOM2,HOOK1,SEMA3A,SERPINB1,JAK3,RARG,XDH,ADAMTS16,LMO7,PLA2G4A,ARHGAP11A,AVPI1,SORBS1,NF2,TP53,TESK2,RNF182,APC2,SYTL2,CYP26A1,CDS1,RCN1,ATP6V0B,MUC16,ACAP2,CDH1,EFR3A,KIF14,DACT1,PLCG2,CNNM4,ACSL4,DLG3,SCN2A,SCN3A,SULF2,SUSD3,CLCN3,AKT1,FZD4,PTPRU,CAPN6,SYNE2,SLC11A2,RAB38,MAP3K6,NFIX,IRS2,DUOX1,DNAJC10,JAK1,SIPA1L1,TRIOBP,KLF5,PRIMA1,SLC25A30,NR3C2,ABCA1,LIFR,NDST3,GOLIM4,ERI2,PKN1,DNAH3,HMGXB4,SLC9A2,SIX4,SCML1,CD109,FOXP2,DTX3L,ADD3,ADORA1,IGSF9,PHF7,PTEN,GALNS,SGK3,ATP8B1,CNOT6L,AMOTL2,SUN2,LONRF3,BCL9,AMFR,PIK3R1,ZKSCAN2,TTC7A,COL7A1,BCAR1,DGKE,FUCA1,MAMDC4,FGFR2,DHRS2,ABCB1,ARRB1,GRIN2D,CENPE,ETAA1,ZMIZ1,NCAPG2,ARHGEF4,GOLGB1 |
| 4.667e-03 | -5.37 | epithelial cell migration | biological process | GO:0010631 | 71 | 15 | 16441 | 1675 |
NOV,SCG2,PTEN,NR4A1,PIK3CA,TGFBR1,LOXL2,EPHB4,PKN1,ANLN,ARSB,EMP2,S100A2,CYP1B1,GPLD1 |
| 4.669e-03 | -5.37 | BIOCARTA_HDAC_PATHWAY | MSigDB lists | BIOCARTA_HDAC_PATHWAY | 28 | 8 | 17758 | 1761 |
CALM2,IGF1R,AKT1,CALM1,PIK3R1,PIK3CA,CALM3,CABIN1 |
| 4.669e-03 | -5.37 | NGUYEN_NOTCH1_TARGETS_UP | MSigDB lists | NGUYEN_NOTCH1_TARGETS_UP | 28 | 8 | 17758 | 1761 |
NQO1,SLC4A3,HDAC1,COL18A1,PSMD10,ITGAV,F2R,S100A13 |
| 4.669e-03 | -5.37 | PID_WNT_SIGNALING_PATHWAY | MSigDB lists | PID_WNT_SIGNALING_PATHWAY | 28 | 8 | 17758 | 1761 |
CTHRC1,FZD4,RYK,WNT3A,FZD5,KREMEN1,FZD6,FZD7 |
| 4.672e-03 | -5.37 | Tetraspannin | pfam domains | PF00335 | 33 | 9 | 16629 | 1696 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,TSPAN7 |
| 4.677e-03 | -5.37 | MICROTUBULE_ORGANIZING_CENTER | MSigDB lists | MICROTUBULE_ORGANIZING_CENTER | 66 | 14 | 17758 | 1761 |
TOP2A,PLK1,PCGF5,DLGAP5,CNTRL,NEK2,ABCA2,TUBG1,BUB1,CEP41,NDE1,ESPL1,SAC3D1,NIN |
| 4.677e-03 | -5.37 | GNF2_PTPRC | MSigDB lists | GNF2_PTPRC | 66 | 14 | 17758 | 1761 |
HLA-B,HECA,MSL1,PARP12,JAK1,SEMA4D,HLA-E,HLA-F,TSC22D3,STK38,OSTF1,GRK6,HLA-C,HLA-A |
| 4.677e-03 | -5.37 | RABL6 (RAB, member RAS oncogene family-like 6) | protein interactions | 55684 | 26 | 8 | 16036 | 1726 |
NKX3-1,PLK2,TP53,BUB1,MYH14,NUP85,MYL12A,MDFI |
| 4.679e-03 | -5.36 | regulation of glomerular filtration | biological process | GO:0003093 | 12 | 5 | 16441 | 1675 |
ADORA1,PDGFB,EMP2,F2R,F2RL1 |
| 4.679e-03 | -5.36 | regulation of Rac protein signal transduction | biological process | GO:0035020 | 12 | 5 | 16441 | 1675 |
STMN3,ARHGAP24,RASGRF1,ARAP3,ARF6 |
| 4.707e-03 | -5.36 | negative regulation of mitochondrion organization | biological process | GO:0010823 | 39 | 10 | 16441 | 1675 |
PPIF,PINK1,AKT1,TP53,PSMD10,VAT1,BCL2L1,SLC25A5,LMNA,IER3 |
| 4.709e-03 | -5.36 | serous | COSMIC cancer mutations | serous | 34 | 9 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 4.710e-03 | -5.36 | HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1) | protein interactions | 3113 | 87 | 18 | 16036 | 1726 |
LTBP1,GOLIM4,ASPM,HLA-F,EPHA4,DSE,B4GALT4,TNFSF9,EFNB1,DAG1,HLA-A,ATP13A2,PNPLA6,SORL1,EGFL7,ERBB3,HS3ST3B1,DCBLD1 |
| 4.711e-03 | -5.36 | response to calcium ion | biological process | GO:0051592 | 113 | 21 | 16441 | 1675 |
PPIF,SCN5A,SLC25A24,SLC25A13,IQGAP1,CALM1,GRIN1,CALM3,ITPR3,FOS,SDC1,RASGRP2,GPLD1,CCND1,CALM2,CPNE2,KCNMB4,STIM1,FOSB,TRPC1,PTGES |
| 4.720e-03 | -5.36 | PTK2 (protein tyrosine kinase 2) | protein interactions | 5747 | 135 | 25 | 16036 | 1726 |
BIN1,HES1,SORBS1,IQGAP1,RET,PIK3R1,TP53,EZR,ERBB2,TNS1,YES1,BCAR1,DAG1,EPS8L2,SH3KBP1,NEO1,SOCS3,PLCG1,IGF1R,PTEN,CTTN,ERBB3,ITGAV,SYK,DEF6 |
| 4.720e-03 | -5.36 | V$ETS2_B | MSigDB lists | V$ETS2_B | 265 | 40 | 17758 | 1761 |
IER5L,CTHRC1,ARAP3,CAST,TSC22D3,TRMT2B,ITPR2,CAMK1D,PSIP1,TEAD3,B4GALNT1,RNF128,SHC3,RGS3,ATP5H,CDKN1B,TWIST1,DIXDC1,RAB20,DAB2IP,KLF9,CACNA1D,SCN2A,CITED2,RBMS2,DOCK4,PCDH1,FURIN,ARHGDIB,LDB2,ZBTB7B,SPNS3,MAPKAPK2,PGF,TMEM164,PLEKHH2,KLF12,CORO1C,AGBL5,LIFR |
| 4.721e-03 | -5.36 | ST_B_CELL_ANTIGEN_RECEPTOR | MSigDB lists | ST_B_CELL_ANTIGEN_RECEPTOR | 40 | 10 | 17758 | 1761 |
NFKBIE,AKT1,NFKBIA,PLCG2,PIK3R1,PIK3CA,PIK3CD,ITPKA,DAG1,SYK |
| 4.734e-03 | -5.35 | GSE12366_GC_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_UP | 177 | 29 | 17758 | 1761 |
LOC81691,SPC25,KIF20A,ST14,TACC1,SLC39A8,PBK,SYNE2,CDC20,SYBU,CDCA2,ROR1,ASB13,SLC25A5,RNF19B,PSMA4,SWAP70,MAP2,DBI,LRIG1,CDCA5,PLK4,UBE2J1,SGK1,CTTN,C12orf75,CCDC88A,SNX30,METAP2 |
| 4.745e-03 | -5.35 | MODULE_53 | MSigDB lists | MODULE_53 | 390 | 55 | 17758 | 1761 |
ENO2,DLGAP5,EPAS1,FOXM1,S100A11,PTTG1,TAP1,NDC80,C5orf30,NRG2,CCNB1,CARD10,SAC3D1,CHPF,M6PR,IER3,TOP2A,CDKN2C,DAPK2,WEE1,ARTN,CTSC,SH3BP1,KCNN4,KIF14,FOSB,IGFBP2,IFIT1,CYP1B1,CKS2,HMMR,PLK1,FADS2,ZWINT,CENPA,S100A4,CDC20,MYBL2,ARHGDIB,GGH,PKMYT1,CCNF,FOS,KIF11,CDK1,PRIM1,MDK,SWAP70,ETS2,GLA,CCNB2,UBE2C,ABCA1,CD33,MAPK12 |
| 4.756e-03 | -5.35 | peptidyl-serine modification | biological process | GO:0018209 | 135 | 24 | 16441 | 1675 |
PLK1,PRKAA2,PINK1,AKT1,TGFBR1,PDK3,CCNB1,PRKACA,PDGFB,CDK1,CDK5R1,GALNT3,MAPKAPK2,RPS6KA2,ADRBK1,CSNK1G1,SGK3,SGK1,AURKA,STK39,MAST4,SYK,HIPK3,MAPK12 |
| 4.762e-03 | -5.35 | ACEVEDO_LIVER_CANCER_DN | MSigDB lists | ACEVEDO_LIVER_CANCER_DN | 510 | 69 | 17758 | 1761 |
LAMP1,ACACB,AVPI1,PPFIBP2,NDRG2,VARS2,HDAC6,OAT,SLC20A1,PHLDA1,CYP39A1,IER3,CCND1,RCN1,APLP2,FAM46A,ZFP36,FOSB,ESPN,PHKA2,CAPN6,ITCH,LYRM1,CDA,EZR,F12,AGPAT2,C19orf66,WFS1,RAP1GAP,MAN2B2,PINK1,PCOLCE,ZNF395,SDC4,PBX3,GSTP1,SIRPA,CXCL16,MLPH,CYR61,KIF13B,COL6A1,UBE2J1,PCYOX1,TMBIM6,ALDH2,SHMT1,OGDHL,FURIN,EIF2AK1,FOS,SFXN5,GNA11,CRISPLD2,FUCA1,NUCB1,MAMDC4,RPL12,PRKAG2,ACADSB,ETS2,FAAH,RND3,NFKBIA,SH3BGRL2,NR4A2,HOOK1,DIS3L |
| 4.797e-03 | -5.34 | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | 185 | 30 | 17758 | 1761 |
GLIS3,LZTFL1,DYNLRB1,CMAS,RAB3B,TMEM68,ARMCX3,OSTM1,CAMKK1,PCBP3,MMADHC,ABCG2,SNN,MCFD2,TP53INP2,SCARB2,AP1M2,RALGPS2,PTEN,RAP2C,RFX5,PRIMA1,MAP3K5,RCAN3,TIAM1,CYBRD1,ZBTB33,CTH,USP43,NXT2 |
| 4.797e-03 | -5.34 | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | 185 | 30 | 17758 | 1761 |
PARP12,GNPDA1,ADCK3,ATP8A1,AMFR,INPP5D,TMX4,ARL4C,PBX3,NKRF,RUNX3,TNFSF9,ABCD4,SLC25A36,PLS3,KLHL2,CCDC92,ARHGAP24,HSF2,RNF220,CNTRL,KBTBD2,RAP2C,RAB11FIP1,VSIG10,PIKFYVE,SNX10,SCN3A,MCCC2,JARID2 |
| 4.797e-03 | -5.34 | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | MSigDB lists | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | 185 | 30 | 17758 | 1761 |
ANXA3,LRRFIP2,NFKBIE,ASPM,SAT1,CBX6,MRAS,CTSZ,TEX2,NPC2,IFIT3,DOCK5,KBTBD11,SPTLC2,ARHGEF16,CD83,WWP2,IER3,FAM46A,SERPINA1,FLRT3,NFKBIA,RAP2C,BCL6,ADCK2,SGK1,PIM1,EGLN3,MAFF,CPPED1 |
| 4.797e-03 | -5.34 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | 185 | 30 | 17758 | 1761 |
FADS2,CEP70,SERPINE2,AKT1,PBK,SLC25A13,OXR1,ANO6,MGAT4B,MYBL2,PRICKLE1,FAM133B,TMEM170B,DHRS3,KREMEN1,GLT8D2,APPBP2,AMZ2,DAZAP1,UBE2Q2,IDE,SWAP70,PSMD1,TSPAN6,PRPS2,CST3,DTX4,MRPS28,NCAPG2,WBP5 |
| 4.797e-03 | -5.34 | GSE13306_RA_VS_UNTREATED_TREG_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_UP | 185 | 30 | 17758 | 1761 |
GRN,CYP26B1,CCNE2,LAMP1,LZTFL1,MRC2,COL6A2,MMD,LGR4,CUL4B,KIF13A,IL27RA,SAV1,DHRS3,CA8,ERP29,BBS2,GLT8D2,SFXN5,PITX2,NOV,EFR3A,MGAT4A,VAT1,RAB20,CTTN,ZMYM1,LTA4H,NRGN,MED22 |
| 4.804e-03 | -5.34 | endometrioid_adenocarcinoma | COSMIC cancer mutations | endometrioid_adenocarcinoma | 8 | 4 | 17775 | 1757 |
GNAS,PTEN,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | mixed_cell_carcinoma | COSMIC cancer mutations | mixed_cell_carcinoma | 8 | 4 | 17775 | 1757 |
FGFR2,PTEN,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | urinary_tract-bladder-other-neoplasm | COSMIC cancer mutations | urinary_tract-bladder-other-neoplasm | 8 | 4 | 17775 | 1757 |
PTEN,PIK3R1,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | cranium | COSMIC cancer mutations | cranium | 8 | 4 | 17775 | 1757 |
AKT1,PTEN,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | central_nervous_system-brain-other-central_neurocytoma | COSMIC cancer mutations | central_nervous_system-brain-other-central_neurocytoma | 8 | 4 | 17775 | 1757 |
AKT1,IDH1,PTEN,TP53 |
| 4.804e-03 | -5.34 | cervix-carcinoma-endocervical_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endocervical_adenocarcinoma | 8 | 4 | 17775 | 1757 |
GNAS,PTEN,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | endometrium-carcinoma-mixed_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_cell_carcinoma | 8 | 4 | 17775 | 1757 |
FGFR2,PTEN,PIK3CA,TP53 |
| 4.804e-03 | -5.34 | central_neurocytoma | COSMIC cancer mutations | central_neurocytoma | 8 | 4 | 17775 | 1757 |
AKT1,IDH1,PTEN,TP53 |
| 4.804e-03 | -5.34 | endocervical_adenocarcinoma | COSMIC cancer mutations | endocervical_adenocarcinoma | 8 | 4 | 17775 | 1757 |
GNAS,PTEN,PIK3CA,TP53 |
| 4.805e-03 | -5.34 | regulation of endothelial cell migration | biological process | GO:0010594 | 106 | 20 | 16441 | 1675 |
ANXA3,AKT1,RGCC,VASH1,PDGFB,ETS1,BCAR1,EMP2,SRPX2,NRP2,HDAC9,GPLD1,PLCG1,SVBP,SP100,ACVRL1,PLPP3,PRCP,DAB2IP,HSPB1 |
| 4.812e-03 | -5.34 | BALDWIN_PRKCI_TARGETS_UP | MSigDB lists | BALDWIN_PRKCI_TARGETS_UP | 34 | 9 | 17758 | 1761 |
NOV,TSPAN6,CBX6,TGOLN2,MPP5,EIF4EBP2,SLC11A2,TRIB2,SEPP1 |
| 4.812e-03 | -5.34 | BIOCARTA_MPR_PATHWAY | MSigDB lists | BIOCARTA_MPR_PATHWAY | 34 | 9 | 17758 | 1761 |
GNAS,RPS6KA1,PAQR5,PRKAR2B,CCNB1,ARPC2,MYT1,CDK1,PAQR7 |
| 4.812e-03 | -5.34 | RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 34 | 9 | 17758 | 1761 |
MAP3K3,ACVR1C,ACVRL1,MAP3K9,TGFBR1,MAPK11,MAP3K5,MAP3K6,MAPK12 |
| 4.822e-03 | -5.33 | TSC1 (tuberous sclerosis 1) | protein interactions | 7248 | 43 | 11 | 16036 | 1726 |
PLK1,NF2,AKT1,NGFRAP1,RPS6KA1,DAPK1,EZR,CDKN1B,CCNB1,CDK1,RHEB |
| 4.822e-03 | -5.33 | DLG2 (discs, large homolog 2 (Drosophila)) | protein interactions | 1740 | 43 | 11 | 16036 | 1726 |
DLGAP1,KCNJ12,SCN5A,FZD4,DLG1,GRIN1,GRIN2D,WNT3A,ABCA1,FZD7,MAPK12 |
| 4.831e-03 | -5.33 | regulation of tissue remodeling | biological process | GO:0034103 | 58 | 13 | 16441 | 1675 |
CA2,IL15,INPP5D,UBASH3B,CST3,INPP4B,TP53,SUCO,BAX,IL18,TMEM64,SYK,ABR |
| 4.840e-03 | -5.33 | regulation of osteoblast proliferation | biological process | GO:0033688 | 22 | 7 | 16441 | 1675 |
CTHRC1,ITGAV,RHOA,SOX8,HPSE,CYR61,FGFR2 |
| 4.840e-03 | -5.33 | regulation of nuclease activity | biological process | GO:0032069 | 22 | 7 | 16441 | 1675 |
TMBIM6,SIRT1,DAB2IP,NEIL1,OAS3,AKT1,BAX |
| 4.840e-03 | -5.33 | regulation of p38MAPK cascade | biological process | GO:1900744 | 22 | 7 | 16441 | 1675 |
MAP3K3,EZR,DAB2IP,PHLPP1,RASGRP1,XDH,DLG1 |
| 4.843e-03 | -5.33 | GSE29618_PDC_VS_MDC_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DN | 193 | 31 | 17758 | 1761 |
PPIF,SLC25A24,LGALS3,IFITM3,IQGAP1,S100A4,BLVRB,PLEKHO1,PTGER4,EFHD2,NDRG2,IL13RA1,ARHGDIB,BLVRA,GSTP1,ADRBK2,LMNA,CST3,NOD2,BCL6,SGK1,ARRB1,SERPINB6,KLF11,OAS3,SERPINB1,TIPARP,ALDH3A2,AHR,ATP2B1,CD33 |
| 4.843e-03 | -5.33 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN | 193 | 31 | 17758 | 1761 |
PLK1,B3GNT2,CCDC109B,CENPA,MPP1,PBK,ATP8A1,PRKCQ,ITPR2,BLVRA,GPSM2,NCKAP1,ATP1B1,CARD10,DGKE,SYTL2,IL17RB,PTPRF,CDKN2C,EPCAM,FAM64A,ETS2,NEK2,AURKA,RTKN2,NOTCH3,EPB41L4B,GLCCI1,CDKN2D,SYTL3,STARD3NL |
| 4.843e-03 | -5.33 | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_DN | 193 | 31 | 17758 | 1761 |
LOC81691,GAA,HSPG2,NQO1,NLRX1,PIP4K2C,LITAF,UBE2A,MORC4,PBX3,IFIT3,LTBP3,RAD23A,WWP2,GABARAPL1,IER3,IRS2,SCARB2,SWAP70,SLC25A4,TIMM8A,SYT7,METTL7A,SELK,EFNA5,MYH14,TAGLN2,MYT1,PRR15,DVL2,FGD1 |
| 4.843e-03 | -5.33 | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | 193 | 31 | 17758 | 1761 |
GRN,PVRL4,SUN2,ATP9A,ATP8A1,BCL9,ITCH,CUL4B,HEXB,CDA,GPSM2,PSIP1,LMNA,SESN3,RPL12,RNF128,CTSC,TIMM8A,FRYL,CORO1C,PLCG2,N4BP3,RAP2C,SPINT2,CDKN1B,RP2,TMEM37,RGS14,CTDSP2,NAGA,TOB1 |
| 4.843e-03 | -5.33 | GSE360_CTRL_VS_L_DONOVANI_DC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_UP | 193 | 31 | 17758 | 1761 |
ZWINT,FAM169A,GNPDA1,MPP1,RPS6KA1,HLA-E,S100A4,SH3BGRL,INPP5D,XYLT1,CTDSPL,PBX3,BLVRA,TRIB2,VASH1,SEPP1,RASSF8,RPS6KA2,ALDH5A1,ITGA3,PRCP,UTP14C,PLCG2,SORL1,AHCY,LTA4H,USF2,TOB1,ATP2B1,MED22,CD33 |
| 4.843e-03 | -5.33 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | 193 | 31 | 17758 | 1761 |
IL15,S100A4,RASA2,IL18,CAMK1D,NUCB2,FAM101B,FAM46C,IL18R1,LTBP3,STX3,DNAJB9,FRMD4B,SLC25A36,CCND1,SESN3,CA2,GPRC5B,HOXA9,BCL6,PRDM5,TMEM51,LRRK1,C10orf54,ECE1,GEM,PTPRE,MYLIP,ABCA1,JARID2,CD33 |
| 4.844e-03 | -5.33 | V$ETS1_B | MSigDB lists | V$ETS1_B | 241 | 37 | 17758 | 1761 |
SPRED1,PSME2,CAST,TSC22D3,RASA2,ITPR2,CAMK1D,PDGFB,CMTM6,ZNF687,SHC3,RGS3,ADAM15,TWIST1,DAB2IP,CACNA1D,SCN2A,PLCB2,RBMS2,ELK3,MCTP1,SH3BGRL,FURIN,KIF1C,ITPR3,SPNS3,EPN3,PLEKHH2,KLF12,MADD,RAP2C,NRG1,HMGA1,RGS14,DEF6,RGMA,ABCG1 |
| 4.849e-03 | -5.33 | CD1B (CD1b molecule) | protein interactions | 910 | 49 | 12 | 16036 | 1726 |
CPD,ADAMTS2,PODXL2,SLC27A6,GALNT12,IMPAD1,NETO2,LRP11,TNFSF9,OCLN,HLA-A,FAM69A |
| 4.861e-03 | -5.33 | PTB | interpro domains | IPR013625 | 8 | 4 | 18293 | 1814 |
TNS1,TNS3,EPS8,EPS8L2 |
| 4.861e-03 | -5.33 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | MSigDB lists | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | 8 | 4 | 17758 | 1761 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 4.861e-03 | -5.33 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR | 8 | 4 | 17758 | 1761 |
ZNF462,CENPA,BORA,SEMA3B |
| 4.861e-03 | -5.33 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN | 8 | 4 | 17758 | 1761 |
TLE1,LGALS3,CAST,SOX9 |
| 4.861e-03 | -5.33 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | 8 | 4 | 17758 | 1761 |
BCL2L1,EGLN3,MAPK8IP1,DAPK1 |
| 4.878e-03 | -5.32 | MODULE_378 | MSigDB lists | MODULE_378 | 399 | 56 | 17758 | 1761 |
LMTK3,FAM169A,CDH22,AASS,MRPS15,SLC25A27,TP53,C6orf106,CTSZ,ISYNA1,NANS,IL18R1,CMTM6,C9orf69,RNF220,CYP1A1,METTL7A,CDK16,PAQR5,ESPN,EPB41L4B,PDE4D,CNOT6L,FAIM,CITED2,SCARA3,FAR2,ATG4D,AMOTL2,TBC1D8B,FMN1,ADCK3,MICB,FURIN,PIP4K2C,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,FUCA1,AMZ2,PTPRF,NEIL1,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,PKIA,RRAGD |
| 4.879e-03 | -5.32 | phospholipid binding | molecular function | GO:0005543 | 349 | 51 | 16491 | 1673 |
PLA2G4A,ANXA3,MTM1,PACSIN2,ARAP3,IQGAP1,ITPR2,TEC,SYTL4,FAM21C,ZFYVE9,SYTL2,ZFYVE16,SNX18,PASK,SGK3,ATP8B1,PLEKHF1,SNX16,DAB2IP,PACSIN1,TIAM1,SNX10,SYTL3,CCDC88A,RASGRP1,SNX7,ARAP2,MCTP1,AKT1,RAPGEF2,AMER1,ITPR3,PCTP,CPTP,SNX12,SYT7,WIPI1,AXL,ITPR1,PIK3C2B,ANXA9,PLD1,SYT13,WDR45B,NRGN,PXDC1,ABCA1,SNX30,ESYT2,ABCG1 |
| 4.881e-03 | -5.32 | organophosphate ester transport | biological process | GO:0015748 | 85 | 17 | 16441 | 1675 |
SLC35D2,SLC25A24,ATP9A,ATP8A1,NPC2,ATP8B3,PCTP,CPTP,ATP10D,SLC25A36,TMEM30A,KCNN4,MFSD2A,ATP8B1,PITPNA,ABCA1,ABCG1 |
| 4.884e-03 | -5.32 | Adherens junction | KEGG pathways | ko04520 | 73 | 16 | 6908 | 758 |
LMO7,PVRL4,WASF3,RHOA,SORBS1,IQGAP1,ERBB2,TGFBR1,TCF7,YES1,PTPRF,PTPRJ,CDH1,IGF1R,PVRL2,FARP2 |
| 4.884e-03 | -5.32 | Adherens junction | KEGG pathways | hsa04520 | 73 | 16 | 6908 | 758 |
LMO7,PVRL4,WASF3,RHOA,SORBS1,IQGAP1,ERBB2,TGFBR1,TCF7,YES1,PTPRF,PTPRJ,CDH1,IGF1R,PVRL2,FARP2 |
| 4.890e-03 | -5.32 | ATGCTGC,MIR-103,MIR-107 | MSigDB lists | ATGCTGC,MIR-103,MIR-107 | 209 | 33 | 17758 | 1761 |
FRMD4A,RET,KIF23,GABRG2,FAM81A,SIX4,NRP2,SIPA1L2,ZNRF2,PACSIN1,WNT3A,TRAM1,SUN2,PHF20L1,PCGF5,CELSR2,SEPT6,FOXJ2,SNTB2,PIK3R1,FURIN,CDK5R1,BSDC1,CNTNAP1,HLF,RAB11FIP2,RAP2C,AMMECR1,CAB39,PITPNA,HMGA1,PIEZO1,NR2C2 |
| 4.923e-03 | -5.31 | Small cell lung cancer | KEGG pathways | ko05222 | 86 | 18 | 6908 | 758 |
CCNE2,AKT1,ITGA6,PIK3R1,CASP9,TP53,COL4A5,BCL2L1,CCND1,ITGA3,PTEN,NFKBIA,PIK3CA,CDKN1B,PIK3CD,ITGAV,TRAF5,CKS2 |
| 4.923e-03 | -5.31 | Small cell lung cancer | KEGG pathways | hsa05222 | 86 | 18 | 6908 | 758 |
CCNE2,AKT1,ITGA6,PIK3R1,CASP9,TP53,COL4A5,BCL2L1,CCND1,ITGA3,PTEN,NFKBIA,PIK3CA,CDKN1B,PIK3CD,ITGAV,TRAF5,CKS2 |
| 4.924e-03 | -5.31 | TRPC1 (transient receptor potential cation channel, subfamily C, member 1) | protein interactions | 7220 | 21 | 7 | 16036 | 1726 |
MX1,TRPC1,ITPR2,RHOA,ITPR3,ITPR1,MDFI |
| 4.924e-03 | -5.31 | NUF2 (NUF2, NDC80 kinetochore complex component) | protein interactions | 83540 | 21 | 7 | 16036 | 1726 |
AURKA,BUB1,CENPE,ZWINT,SPC25,DGKE,NDC80 |
| 4.924e-03 | -5.31 | ITGA3 (integrin alpha 3) | protein interactions | 3675 | 21 | 7 | 16036 | 1726 |
PDIA3,BIN1,TIMP2,FBXO6,ITGA3,CD82,CD9 |
| 4.929e-03 | -5.31 | BURTON_ADIPOGENESIS_11 | MSigDB lists | BURTON_ADIPOGENESIS_11 | 53 | 12 | 17758 | 1761 |
KIF5B,LMO7,SMARCA2,NR3C1,ARFGEF1,ALCAM,SLC12A2,AHR,RASA1,CCDC88A,NFIX,SLC25A36 |
| 4.929e-03 | -5.31 | LEE_EARLY_T_LYMPHOCYTE_DN | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_DN | 53 | 12 | 17758 | 1761 |
HLA-B,PTPRJ,HLA-E,HLA-F,NLRC5,IL27RA,HLA-C,TBC1D4,DENND2D,HLA-A,SCML1,STK17A |
| 4.930e-03 | -5.31 | PROTEIN_TARGETING | MSigDB lists | PROTEIN_TARGETING | 109 | 20 | 17758 | 1761 |
NFKBIE,AKT1,PEX6,PDIA3,STRADB,ICMT,BARD1,ZFYVE9,OPTN,ATG4A,ZFYVE16,AP1M2,CDH1,KIF13B,BCL6,LTBP2,F2R,TRAM1,ATG4D,MDFI |
| 4.950e-03 | -5.31 | response to metal ion | biological process | GO:0010038 | 299 | 45 | 16441 | 1675 |
SCN5A,CASP3,SLC25A24,SLC25A13,IQGAP1,MTL5,CALM3,CCNB1,SDC1,CALM2,CCND1,CPNE2,CYP1A1,CDH1,CA2,STIM1,PTEN,FOSB,BAX,TFAP2A,TRPC1,CDKN1B,IGFBP2,S100A13,PPIF,CALM1,CASP9,GRIN1,ACO1,SLC11A2,GGH,LOXL2,ITPR3,FOS,CYB5A,FAS,RASGRP2,GPLD1,ATP13A2,FECH,KCNMB4,ATP7B,LTA4H,PTGES,CYBRD1 |
| 4.960e-03 | -5.31 | KIM_WT1_TARGETS_8HR_UP | MSigDB lists | KIM_WT1_TARGETS_8HR_UP | 162 | 27 | 17758 | 1761 |
PDGFC,GOLIM4,ENO2,ATP9A,PLAUR,PLEKHO1,SOX9,TNS1,SLC20A1,SIRPA,BTG3,TIMP3,SWAP70,DOK4,CSF1,IL6ST,WWP1,HMGA1,PIM1,PIK3CD,GEM,ZMIZ1,ST3GAL1,ULBP2,MAFF,ATP2B1,METAP2 |
| 4.960e-03 | -5.31 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | 162 | 27 | 17758 | 1761 |
ZNF462,CASP3,DDB2,PHF20L1,DYNLRB1,RIPK2,S100A11,FMN1,SLC39A8,BCL9,HABP4,OSGIN2,SLC11A2,KCTD12,CD274,STK17B,FRMD4B,NCOA3,CTSC,FRAS1,DACT1,SPINT2,GTF2F2,RAB11FIP1,PTPRE,SNX10,RASGRP1 |
| 4.960e-03 | -5.31 | Integrated Cancer pathway | WikiPathways | WP1971 | 35 | 10 | 4455 | 516 |
PLK1,CASP3,AKT1,JAK1,PTEN,CASP9,TP53,BAX,BARD1,CDK1 |
| 4.977e-03 | -5.30 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 307 | 45 | 17758 | 1761 |
CTDSPL,ARFGEF1,GABRG2,PBX3,INTS8,ZNF385B,GRM5,SS18,APLP2,SIPA1L2,UBE2Q2,ACAP2,RIMS3,BHLHE41,KLF3,REEP1,IRF2,DAB2IP,PDE4D,PIKFYVE,ANO4,CITED2,GAD1,CHSY3,TMTC1,PDGFC,PHF20L1,LCA5,FZD4,SAT1,PIK3R1,ZFAND5,ANTXR1,SP4,KBTBD2,LRIG1,MADD,OVOL1,PCDH19,IRF7,HS3ST3B1,ZMIZ1,TBC1D4,GAB1,DOCK9 |
| 4.989e-03 | -5.30 | sulfuric ester hydrolase activity | molecular function | GO:0008484 | 17 | 6 | 16491 | 1673 |
GNS,ARSB,ARSG,ARSK,GALNS,SULF2 |
| 4.994e-03 | -5.30 | regulation of peptide transport | biological process | GO:0090087 | 267 | 41 | 16441 | 1675 |
ILDR1,IQGAP1,CACNA2D2,PSMD10,IL18,HMGN3,ITPR2,SYTL4,PRKACA,SLC8B1,IL18R1,ANO1,NOV,ADORA1,CA2,CDK16,BMP7,PASK,KCNS3,CACNA1D,MYRIP,MYT1,RHOA,ACVR1C,SYBU,LITAF,PRKCQ,PRKAR2B,ITPR3,SLC25A5,GPLD1,GNAS,IRS2,SLC25A4,SYT7,ITPR1,NFKBIA,ARRB1,EFNA5,SPCS3,GPER1 |
| 5.002e-03 | -5.30 | astrocyte projection | cellular component | GO:0097449 | 8 | 4 | 17570 | 1756 |
EZR,PINK1,ADGRG1,GRM5 |
| 5.006e-03 | -5.30 | CTGCAGY_UNKNOWN | MSigDB lists | CTGCAGY_UNKNOWN | 713 | 92 | 17758 | 1761 |
CCNE2,SPRED1,PPM1J,TSC22D3,CAMK1D,APC2,PDGFB,SYTL2,CALM2,SH3BP1,DPYSL2,LMO4,SLC44A1,KCNS3,EPB41L4B,PDE4D,SCN2A,DLG3,ETV4,FRS3,FZD4,SH3BGRL,ATP1B1,ALCAM,NFIX,DPYSL3,PGF,AMZ2,KLF12,C19orf66,NGFRAP1,ZNF367,HOXA9,SLC9A6,NKD1,NRG1,PRIMA1,NRGN,NR3C2,IER5L,FRMD4A,ENO2,NUAK1,KLHL13,ETV5,ARMC7,CALM3,NDUFA4,FAM81A,TSPAN7,SIRPA,HDAC9,MECOM,IRF2BPL,TFAP4,ADD3,FLRT3,EXOC8,SORL1,TNFRSF12A,WWP1,TSPAN13,PIM1,CITED2,C9orf9,DLGAP1,TGIF1,ADAMTS2,ELK3,RHOA,PLEKHA6,ADCK3,PIK3R1,CALM1,FBXO9,COL7A1,PELI3,FOS,EPN3,SMTNL2,ITGA7,NFKBIA,RHOBTB2,GRIN2D,FHL1,GEM,DEF6,RUSC1,JARID2,ABCG1,DIS3L,SNPH |
| 5.007e-03 | -5.30 | PUJANA_BRCA2_PCC_NETWORK | MSigDB lists | PUJANA_BRCA2_PCC_NETWORK | 408 | 57 | 17758 | 1761 |
CCNE2,SPC25,DLGAP5,IL15,FOXM1,PTTG1,NDC80,KIF23,CCNB1,BARD1,STIL,PSIP1,LBR,HMGXB4,FANCI,SAC3D1,TOP2A,CDKN2C,HSF2,CNTRL,KIF14,SIVA1,TBCD,BAX,PLK4,BUB1,PIKFYVE,MYBL1,NR2C1,MPHOSPH9,ABCC1,SEPHS1,CKS2,HMMR,DDB2,ZWINT,CENPA,ZNF84,SEPT6,STAU2,CDC20,MYBL2,PRKCQ,TCF7,ARHGDIB,CCNF,H2AFV,KIF11,CDK1,DCP2,PRIM1,AURKA,CENPE,UBE2C,CCNB2,ESPL1,MELK |
| 5.083e-03 | -5.28 | regulation of transcription from RNA polymerase II promoter | biological process | GO:0006357 | 1740 | 209 | 16441 | 1675 |
TXN,EPAS1,CRYM,TSC22D3,HEXB,LMCD1,MORF4L2,EPCAM,ZFYVE16,HSF2,GRHL1,NPNT,ZCCHC12,ZFP36,MITF,FOSB,ELF5,DLG1,ABCA2,IRF2,CRY2,ZBTB18,MYBL1,ZNF462,PLK1,THRB,PCGF5,SMARCA2,KCNIP3,TNIP1,CITED4,CBX6,NFE2L1,EZR,TFAP2C,LDB2,CDK1,ARF4,AHRR,KLF12,ZNF367,PRDM5,NOD2,HDAC1,KLF11,NFKBIZ,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,DGKQ,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,GATA2,MEGF8,BHLHE41,RFX5,MYDGF,C10orf54,WNT3A,ETV7,MDFI,TRAK2,ELK3,RGMB,SALL4,STAT4,MYBL2,TCF7,ELK1,NFIB,FOXD2,ONECUT1,NCOA3,ETS2,SEMA4D,SETD3,NFKBIA,TCEAL4,NLRC5,NR4A2,PER3,RARG,TMEM173,KLF7,EGLN1,FOXO6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,OSR2,LPIN3,TTC21B,CCND1,SS18,SP100,DACT1,LMO4,BCL6,DAB2IP,TWIST1,NOTCH3,EGLN3,ETV4,MED30,NR2C1,SIRT1,RIPK2,AKT1,FOXJ2,DRAP1,HTATIP2,GLO1,PYGO1,GTF2A2,CD40,SP4,ARHGAP35,NFIX,JADE1,RBL1,WFS1,PEX2,OVOL1,TLE1,KLF5,NRG1,IRF7,CBX7,GLIS3,NKX3-1,CKAP2,LRP4,PSMD10,PBX3,AES,HMGN3,PKN1,ETS1,TEAD3,SIX4,HDAC9,WWP2,CTNNBIP1,IRF2BPL,TOP2A,E2F7,BMP7,TOX2,GTF2F2,TFAP2A,TMBIM6,KLF9,CITED2,NCOA2,MED22,WBP5,NFE2L3,TGIF1,HES1,RHOA,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,LITAF,PPARA,ZKSCAN2,RGCC,MAML2,RUNX3,YES1,FOS,TCEAL8,FOXL1,PITX2,FGFR2,ACVRL1,TWSG1,TBX18,NR4A3,ARRB1,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,PKIA,RGMA,JARID2 |
| 5.090e-03 | -5.28 | positive regulation of leukocyte proliferation | biological process | GO:0070665 | 121 | 22 | 16441 | 1675 |
HES1,CD55,RIPK2,IL15,HLA-E,IL18,PRKCQ,CD274,CD40,TNFSF9,EFNB1,HLA-A,IRS2,IL6ST,CSF1,BCL6,IGFBP2,SLC39A10,ICOSLG,WNT3A,JAK3,SYK |
| 5.096e-03 | -5.28 | negative regulation of defense response to virus | biological process | GO:0050687 | 17 | 6 | 16441 | 1675 |
IFIT1,NLRX1,ITCH,MICB,TSPAN6,TRAF3IP1 |
| 5.105e-03 | -5.28 | PID_CXCR4_PATHWAY | MSigDB lists | PID_CXCR4_PATHWAY | 102 | 19 | 17758 | 1761 |
RHOA,SSH1,AKT1,INPP5D,ITCH,ITGA6,PIK3R1,YES1,GRK6,BCAR1,ITGA3,ADRBK1,PTEN,ITGA7,LIMK1,PIK3CA,ITGAV,PIK3CD,PLCB2 |
| 5.109e-03 | -5.28 | cytoskeletal part | cellular component | GO:0044430 | 1403 | 169 | 17570 | 1756 |
MYL9,ADD1,NDRG2,SYTL4,CCNB1,HDAC6,FAM101B,SPTB,CALM2,RPS6KA2,STIM1,CNTRL,DPYSL2,CEP78,DLG1,ABCA2,TUBG1,HYLS1,RP2,MYH14,CTTN,CCDC38,PLK1,SPEF2,PCGF5,KIFC2,SNTB2,STAU2,EZR,PRKAR2B,KIF13A,CCNF,ANLN,SLC25A5,CDK1,DZIP1L,DPYSL3,PLEKHG6,NEIL1,MID1IP1,DNM1L,MAP2,PLK2,TRAF3IP1,FAM110C,TMOD2,HSPB1,TRAF5,MYL12B,LASP1,PIFO,BMF,CALM3,KIF23,LMNA,FRY,KIF13B,TBCD,NEK2,LRIF1,MPHOSPH9,NUP85,TPGS2,C9orf9,KIF20A,CALM1,NUBP1,RANBP9,MAPKAPK2,PLEKHH2,AGBL5,FAM83D,AURKA,MDH1,NDE1,ARPC2,CFAP20,SHROOM2,HOOK1,CCNB2,RUSC1,GAS2L1,DYNLRB1,SORBS1,NF2,UPF3B,DLGAP5,CEP70,RPS6KA1,IQGAP1,ACTR8,PKP2,BCL2L1,PRKACA,APC2,STIL,MNS1,APPBP2,LRRC45,SS18,SCNN1A,CDH1,KIF14,PLK4,ESPN,PDE4D,SNX10,ZNF365,MYO5B,CAMSAP3,AKT1,CAPN6,SEPT6,CDC20,CCSAP,KIF1C,NUSAP1,MYL12A,GABARAPL1,NIN,CEP162,BFSP1,STK26,SHROOM3,TRIOBP,SPTBN5,RGS14,REEP4,COBL,TTC8,FBLIM1,CKAP2,POC1B,RASSF7,CDCA8,DNAH3,SAC3D1,KIF5B,CCDC92,TOP2A,PHF7,LLGL2,CALD1,TFAP2A,KLC3,CLIP2,SPRY2,MYO5A,LCA5,TACC1,FMN1,ASPM,SYBU,PARP4,RGCC,YES1,AIF1L,KIF11,BBS2,DCTN6,PPP2R3C,CENPE,GPER1,GEM,WDR62,CEP41,ESPL1,SNPH,DIS3L |
| 5.113e-03 | -5.28 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | molecular function | GO:0016820 | 107 | 20 | 16491 | 1673 |
ATP8A1,ATP2C2,TAP1,ABCG2,ATP1B1,ABCD4,ATP13A2,TAPBP,ATP6V0B,ATP1A1,ATP7B,PCYOX1,ABCA2,ABCB1,ABCD1,ATP1B3,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 5.118e-03 | -5.28 | central_nervous_system-brain-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_II | 444 | 61 | 17775 | 1757 |
ARHGAP11A,MRC2,FRMD4A,NF2,HSPG2,PPM1J,PYROXD2,RET,TP53,ERBB2,ASAH1,PLXNA1,DNAH3,FAM167A,TYMP,DOPEY2,ZNF687,ARTN,IGSF9,ADRBK1,ALPP,CYP4F11,PTEN,IQCE,MEGF8,ZDHHC23,PIK3CA,ARVCF,RTKN2,MAPK11,NOTCH3,PIM1,NR2C1,CCDC88A,RASGRP1,RIMS2,SCN3A,ACBD5,TRIM8,PCDH1,KLK5,ERMAP,AKT1,MFSD2B,PIK3R1,UTRN,FNDC3A,NPHP3,PRKRA,IDH1,GNA11,GNAS,TJP3,ATP7B,NLRC5,CSTF2,SPTBN5,RGS14,CPEB2,NXT2,ESYT2 |
| 5.124e-03 | -5.27 | Sulfatase | pfam domains | PF00884 | 17 | 6 | 16629 | 1696 |
GNS,ARSB,ARSK,ARSG,GALNS,SULF2 |
| 5.124e-03 | -5.27 | Cyclin_C | pfam domains | PF02984 | 17 | 6 | 16629 | 1696 |
CCNE2,CCNJL,CCND1,CCNF,CCNB1,CCNB2 |
| 5.134e-03 | -5.27 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | 178 | 29 | 17758 | 1761 |
TRIM2,MOSPD2,NR3C1,HLA-E,FHDC1,TP53,ACO1,TDRKH,YES1,CAMK1D,EMP2,SLC20A1,ANKRD29,SH3KBP1,TRIM9,PITX2,CYR61,FJX1,ENPP5,GALNS,STEAP2,PPM1H,PCDH19,RP2,CENPE,GLA,NCAM1,MYO5A,NR2C2 |
| 5.134e-03 | -5.27 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | 178 | 29 | 17758 | 1761 |
SYPL1,COL9A3,ING1,ALDH2,SLC37A1,ADD1,IL13RA1,SAV1,BMP2K,PARM1,SWAP70,BANK1,CA2,METTL7A,BHLHE41,KCNN4,PLCG2,ITPR1,PAPSS1,UBE2J1,OPN3,TLE1,ZNF165,TSPAN13,SYK,GM2A,CKAP4,SCN3A,MAPK12 |
| 5.139e-03 | -5.27 | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | 147 | 25 | 17758 | 1761 |
LZTFL1,CCDC109B,CDKN1C,TSC22D3,CR2,LRRC1,LDB2,SLC25A5,DHRS3,ETS1,CYB5A,PRIM1,NCOA3,ADD3,IL6ST,SRR,FAM102A,PIK3C2B,DIXDC1,RARG,TOB1,NCOA2,PKIA,SCN3A,FAM69A |
| 5.144e-03 | -5.27 | regulation of protein localization to cell periphery | biological process | GO:1904375 | 65 | 14 | 16441 | 1675 |
KIF5B,LZTFL1,SORBS1,ITGA3,PPP2R5A,AKT1,PIK3R1,DLG1,EZR,GPER1,BCL2L1,ARF6,ARHGEF16,STX3 |
| 5.144e-03 | -5.27 | regulation of protein localization to plasma membrane | biological process | GO:1903076 | 65 | 14 | 16441 | 1675 |
KIF5B,LZTFL1,SORBS1,ITGA3,PPP2R5A,AKT1,PIK3R1,DLG1,EZR,GPER1,BCL2L1,ARF6,ARHGEF16,STX3 |
| 5.153e-03 | -5.27 | BENPORATH_SOX2_TARGETS | MSigDB lists | BENPORATH_SOX2_TARGETS | 696 | 90 | 17758 | 1761 |
EXPH5,ARHGAP11A,MTM1,SPRED1,UGT8,GRHL2,CNOT8,ARFGEF1,ERBB2,MORF4L2,GRK6,RAD23A,CCND1,RAB15,SCNN1A,CTGF,UBE2T,DPYSL2,SLC44A1,TUBG1,CDH3,VAT1,EGLN3,ARL4D,DVL2,CTH,SEPT6,CYB5R2,FOXJ2,CASP9,SAT1,NUSAP1,ROR1,PIF1,LOXL2,SAV1,ICMT,ALCAM,ADRBK2,CDK1,COL12A1,ARF4,FZD7,DPYSL3,KCNMB4,GNPTAB,PRKCDBP,TLE1,KLF5,ZNF701,PCSK5,PRSS8,IER5L,LASP1,SORT1,CDK17,PPP1R2,GGA1,TMEM55B,PDCL,DHRS3,PPP2R3A,TMEM63A,HDAC9,AKIRIN1,TOP2A,ADD3,CA2,CYR61,CDK16,BMP7,SGK3,FXYD5,IGFBP2,ALDH7A1,NFE2L3,BCL9,EPHA1,KIF11,RASA1,PITX2,CACHD1,SERPINA1,TJP3,FGFR2,PGM2L1,PPP2R3C,CEP41,UBE2C,JARID2 |
| 5.165e-03 | -5.27 | human chr2q22 | chromosome location | human chr2q22 | 2 | 2 | 26250 | 1887 |
NEB,ARHGEF4 |
| 5.165e-03 | -5.27 | human chrXq21.33-q22.3 | chromosome location | human chrXq21.33-q22.3 | 2 | 2 | 26250 | 1887 |
ARMCX6,TMSB15A |
| 5.174e-03 | -5.26 | phagocytic vesicle | cellular component | GO:0045335 | 80 | 16 | 17570 | 1756 |
LAMP1,ANXA3,CLCN3,HLA-E,HLA-F,RAB23,RAB38,HLA-A,ATP6V0B,HLA-B,RAB11FIP1,RAB20,HLA-C,ITGAV,ABCA1,SYK |
| 5.191e-03 | -5.26 | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | 186 | 30 | 17758 | 1761 |
PRSS8,SYPL1,MTM1,GCA,HSPG2,NUAK1,PPARA,LITAF,ASAH1,RNF113A,GALNT7,BLVRA,DPP8,NUP62CL,CASP4,SRPX2,CCDC92,PTPRF,SNTA1,HLA-B,CARD8,RPL12,RBM47,FAM189A1,FRYL,PEX2,COL6A1,SYT13,HOXC13,FRS3 |
| 5.191e-03 | -5.26 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | 186 | 30 | 17758 | 1761 |
SUN2,ATL1,NFKBIE,ADCK3,FOXJ2,TSC22D3,PLEKHO1,RC3H2,KIF1C,PTGFRN,MESDC2,SGPL1,LRRC42,ARHGAP24,SCARB2,ADD3,RNF128,JAK1,CYR61,LMO4,PRPS2,TMC5,PCYOX1,FXYD5,CCDC82,SH3BGRL2,RELL1,MAP3K5,WBSCR27,ARF6 |
| 5.191e-03 | -5.26 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 186 | 30 | 17758 | 1761 |
ANXA3,LTBP1,GCLM,TRIM2,COL6A2,SSH1,ZCCHC24,PLXNA1,MCFD2,ARHGEF40,PHLDA1,GLT8D2,SRPX2,PPP2R3A,SS18,RPS6KA2,SLC25A4,UAP1,NGFRAP1,KCNK1,DNM1L,IMPAD1,DACT1,LRIG1,RRBP1,TPST1,TLE1,TWIST1,TNFRSF12A,CRTAP |
| 5.191e-03 | -5.26 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | 186 | 30 | 17758 | 1761 |
CCNE2,ENPP4,GFPT1,MTM1,DEPDC1,FIGNL1,PLAUR,PBK,SEPT6,PDE5A,KCTD12,GGH,PIF1,ANLN,DDR1,PSIP1,KCTD9,AIM1L,DDOST,FAM64A,FAM46A,OSBPL3,PLK4,WWP1,DONSON,BUB1,STK39,ETAA1,MYBL1,METAP2 |
| 5.191e-03 | -5.26 | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | MSigDB lists | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | 186 | 30 | 17758 | 1761 |
BIN1,CCNI,SUN2,SIGIRR,SMARCA2,NKX3-1,GGA1,S100A4,DNAJB2,CNOT8,INPP5D,ITGA6,PIK3R1,FBXO9,SESN1,MARCH8,PLCG1,ACAP2,PTEN,ALPP,STK38,FAM117A,RGS14,CITED2,TMEM159,CNPY3,MYBL1,NR3C2,CTDSP2,EHD1 |
| 5.191e-03 | -5.26 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP | 186 | 30 | 17758 | 1761 |
ADAMTS2,MRC2,CDK17,ARAP3,HOXB7,FOXJ2,PBK,ETV5,FBXO2,DHX8,PRSS22,EPHA1,GNA11,TMPRSS4,PRDM11,KLHL2,CYP1A1,SLC16A6,FRAS1,BDH1,MADD,MAP3K9,ABCA2,RAB20,PIEZO1,EPB41L4B,FZD5,SGCB,L1CAM,IGSF3 |
| 5.191e-03 | -5.26 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | 186 | 30 | 17758 | 1761 |
MAP3K3,DOCK4,THRB,TRIM8,REPS2,MOSPD2,IFITM3,HEBP1,RPS6KA1,CDA,ERBB2,PSME1,SLC7A2,INTS8,SNN,SPTLC2,FOS,HLA-B,TYMP,MSL1,PPP2R5A,SP100,SECTM1,IRF2,PITPNA,RAB20,EIF4EBP2,CNPY3,PTGES,CPPED1 |
| 5.191e-03 | -5.26 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | 186 | 30 | 17758 | 1761 |
SUN1,LOC81691,ELK3,ALDH2,UPF3B,FAM169A,ADD1,ETV5,PBX3,NANS,FNDC3A,LHFPL2,ALCAM,GLCE,HDAC9,MAN2A2,ARHGAP24,TMEM164,RNF220,UEVLD,METTL7A,PPP4R1,OTUB2,TSPAN13,ETAA1,TLN2,PTPRE,SLC25A38,SGCB,BTBD3 |
| 5.196e-03 | -5.26 | neural crest cell migration | biological process | GO:0001755 | 52 | 12 | 16441 | 1675 |
PITX2,SEMA6B,SEMA4D,CORO1C,RET,TWIST1,SEMA3G,SOX8,SEMA3A,EFNB1,FGF19,SEMA3B |
| 5.196e-03 | -5.26 | regulation of morphogenesis of a branching structure | biological process | GO:0060688 | 52 | 12 | 16441 | 1675 |
PDGFA,HOXB7,LGR4,FGFR2,BMP7,SOX9,ETV5,NTN4,TACSTD2,SOX8,ETV4,SIX4 |
| 5.222e-03 | -5.25 | V$SP1_Q2_01 | MSigDB lists | V$SP1_Q2_01 | 234 | 36 | 17758 | 1761 |
LASP1,HOXB7,GGA1,THRA,CAMKK1,ETV5,TIPRL,SIX4,PPP2R3A,CHPF,MECOM,APLP2,ZNF687,SNX18,ZFP36,BHLHE41,FUT8,SRR,BCL6,ANKRD12,CDH3,ERBB3,NOTCH3,CACNA1D,LYRM1,NFE2L1,PDIK1L,CDK5R1,PIAS3,ONECUT1,ARHGEF19,PTPRJ,CORO1C,AGBL5,PITPNA,KLF7 |
| 5.222e-03 | -5.25 | V$SP1_Q4_01 | MSigDB lists | V$SP1_Q4_01 | 234 | 36 | 17758 | 1761 |
LASP1,UGP2,HOXB7,IQGAP1,NRG2,HDAC6,TIPRL,SH3KBP1,APLP2,SNX18,PRICKLE3,BHLHE41,WWP1,CACNA1D,MYLIP,CYP26B1,CPD,DRAP1,LYRM1,NUB1,EPHA1,ELK1,PRKRA,PDIK1L,GNA11,CDK5R1,PIAS3,ONECUT1,TIMP3,SWAP70,CORO1C,SLC9A6,PTK7,AGBL5,PITPNA,KLF11 |
| 5.231e-03 | -5.25 | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 194 | 31 | 17758 | 1761 |
UNKL,BIN1,RMND5A,SYPL1,LTBP1,CDK17,UBASH3B,CACNA2D2,GABRG2,ARFRP1,HEATR5A,RAD17,ANTXR1,STK17B,RANBP9,KIAA1161,MUC16,UBE2Q2,RBM47,RNF128,TWSG1,MATN2,PGRMC1,DTX4,RHOBTB2,SORL1,PIEZO1,ARSB,MYLIP,TOB1,WBP5 |
| 5.231e-03 | -5.25 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | 194 | 31 | 17758 | 1761 |
LAMP1,ENPP4,LASP1,ARAP2,SSH1,NLRX1,CD63,TACC1,ZCCHC24,ACTR8,ITCH,FURIN,DHX8,YES1,CAMK1D,IL18R1,TIPRL,ATP10D,GALNT3,ZFYVE16,ZNF432,DNM1L,PLCG2,RAB11FIP1,ALPK1,NCAM1,PTPRE,APOBEC3G,SYK,NCOA2,JARID2 |
| 5.231e-03 | -5.25 | GSE17721_LPS_VS_POLYIC_1H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDM_UP | 194 | 31 | 17758 | 1761 |
SIRT1,FADS2,ACACB,TGIF1,ARHGEF3,KIF20A,PLSCR1,FRMD6,PCBP3,LPGAT1,SPATA13,PTGER4,PKP2,BCL2L1,LACTB2,NUCB2,TCEAL8,FOS,CARD10,DNAJB9,CDK5R1,CYP1A1,ETS2,CYR61,RND3,ZFP36,CSF1,SELK,ALDH7A1,TIPARP,MAFF |
| 5.231e-03 | -5.25 | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_DN | 194 | 31 | 17758 | 1761 |
ARHGEF3,B3GNT2,MMD,PLSCR1,KLHL13,DNAJC3,RASA2,CYS1,PIK3R1,OSGIN2,PRKCQ,PRSS22,RNF19B,MAP3K6,TNFSF9,COL12A1,EDNRA,IRS2,PLCG1,RPS6KA2,ETS2,SPIN4,WIPI1,SYT7,NGFRAP1,MMP17,CD70,ICOSLG,TRAF5,PROM2,EHD1 |
| 5.231e-03 | -5.25 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 194 | 31 | 17758 | 1761 |
MX1,GAA,TIMP2,PSMB4,IFITM3,AASS,DAP,DNAJB2,PPFIBP2,TAP1,GDF15,TP53I11,SRPX2,H1FX,SAC3D1,FUCA1,RPL12,SH3BP1,RBL1,NMI,PLCG2,SECTM1,RHOBTB2,AKR1B1,IRF7,CTSA,CNPY3,MAFF,ALDH3A2,RIMS2,EHD1 |
| 5.235e-03 | -5.25 | positive regulation of JNK cascade | biological process | GO:0046330 | 114 | 21 | 16441 | 1675 |
RIPK2,FZD4,EPHA4,PKN1,MAP3K6,FGF19,FZD7,CTGF,ANKRD6,NOD2,MAP3K9,DAB2IP,MDFIC,FZD5,MAP3K5,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI |
| 5.247e-03 | -5.25 | heart development | biological process | GO:0007507 | 440 | 62 | 16441 | 1675 |
CASP3,GAA,SCN5A,NKX3-1,GRHL2,HSPG2,BVES,SOX9,PKP2,ERBB2,TGFBR1,NCKAP1,CCNB1,DHRS3,STIL,PDGFB,FGF19,LMNA,HDAC9,MECOM,RPS6KA2,SETDB2,ITGA3,ADRBK1,PTEN,CYR61,GATA2,FLRT3,MEGF8,LMO4,ADAM15,TWIST1,ECE1,ERBB3,EPHB4,WNT3A,CITED2,SGCB,DVL2,HES1,SALL4,PPARA,SAV1,NPHP3,FOXL1,GNA11,C3orf58,EDNRA,PITX2,PTPRJ,FAT4,PDLIM3,FGFR2,TBX18,TRAF3IP1,ALPK3,NRG1,OSR1,ZMIZ1,GAB1,PCSK5,EGLN1 |
| 5.247e-03 | -5.25 | phagocytic vesicle membrane | cellular component | GO:0030670 | 53 | 12 | 17570 | 1756 |
LAMP1,HLA-B,ANXA3,ATP6V0B,HLA-E,HLA-F,RAB11FIP1,RAB23,RAB20,HLA-C,RAB38,HLA-A |
| 5.247e-03 | -5.25 | PYROPHOSPHATASE_ACTIVITY | MSigDB lists | PYROPHOSPHATASE_ACTIVITY | 226 | 35 | 17758 | 1761 |
PEX6,RALBP1,ARL4C,ABCG2,DHX8,MRAS,RAB6A,ABCD4,DIRAS3,TOP2A,ABCA2,ATP8B1,RAB27B,ARL4D,ATP2B1,ABCC1,RAB3B,RHOA,ARFRP1,ATP1B1,PIF1,GNA11,ARF4,RHEB,GNAS,TAPBP,ENPP1,ATP1A1,RND3,DNM1L,ATP7B,DOLPP1,ATP1B3,ARF6,ABCG1 |
| 5.248e-03 | -5.25 | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | MSigDB lists | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | 117 | 21 | 17758 | 1761 |
PRSS8,PSMB4,PLSCR1,GLO1,HMGN3,OAT,SLC25A5,RHEB,ARF4,GNAS,BTG3,EFR3A,NMI,RANBP1,SPINT2,CD9,MDH1,IFIT1,ATP1B3,MELK,CKS2 |
| 5.255e-03 | -5.25 | SANSOM_APC_MYC_TARGETS | MSigDB lists | SANSOM_APC_MYC_TARGETS | 202 | 32 | 17758 | 1761 |
FOXM1,FLYWCH2,THRA,TP53,ARFGEF1,BCL2L1,RAD23A,CCND1,BMP7,SIVA1,FUT8,FAM63A,TNFRSF12A,SGCB,MED22,MCCC2,SEMA3B,OPLAH,CENPA,SHMT1,NUB1,GYLTL1B,VEZT,DAG1,SCRN2,SLC6A6,DNM1L,SEMA4D,CORO1C,AMMECR1,FZD5,WDR62 |
| 5.265e-03 | -5.25 | V$FAC1_01 | MSigDB lists | V$FAC1_01 | 210 | 33 | 17758 | 1761 |
BMF,REPS2,HOXB7,EPS8,CALM3,NUP62CL,EFNB1,SIX4,NRP2,HDAC9,CALM2,ITGA3,ITGB8,ANKS1B,LHX6,SGK1,CACNA1D,SMARCA2,SAT1,CALM1,NFIB,NFIX,PITX2,GNAS,TAPBP,ACADSB,NKD1,FAM117A,KLF11,SEMA3A,NR3C2,KLF7,JARID2 |
| 5.269e-03 | -5.25 | lipid transport | biological process | GO:0006869 | 236 | 37 | 16441 | 1675 |
PLA2G4A,PRKAA2,ACACB,CPT2,ATP9A,ATP8A1,ANO9,SLC27A6,OSBPL3,KCNN4,FABP6,ABCA2,ATP8B1,SORL1,ABCD1,ACSL4,ANO4,GM2A,NCOA2,FZD4,ANO6,PPARA,ATP8B3,NPC2,PCTP,SPNS3,ATP10D,CPTP,PRKAG2,MFSD2A,TMEM30A,SLC27A1,PITPNA,ABCA1,APOL2,ESYT2,ABCG1 |
| 5.282e-03 | -5.24 | very long-chain fatty acid-CoA ligase activity | molecular function | GO:0031957 | 8 | 4 | 16491 | 1673 |
SLC27A1,ACSL4,SLC27A6,SLC27A3 |
| 5.296e-03 | -5.24 | TSH signaling pathway | WikiPathways | WP2032 | 64 | 15 | 4455 | 516 |
GNAS,KCNIP3,AKT1,IGF1R,JAK1,RPS6KA1,PIK3R1,PIK3CA,CDKN1B,SCRIB,PLD1,PDE4D,RAP1GAP,FOS,MYL12B |
| 5.296e-03 | -5.24 | positive regulation of neurogenesis | biological process | GO:0050769 | 349 | 51 | 16441 | 1675 |
GRN,BIN1,FOXO6,SERPINE2,RET,EPHA4,ETV5,CAMK1D,CRABP2,GRM5,ITGA3,GATA2,IL6ST,MEGF8,BMP7,BCL6,TNFRSF12A,DAB2IP,PACSIN1,WNT3A,TIAM1,RIMS2,TLE6,TGIF1,HES1,RHOA,TIMP2,MMD,ASPM,RAPGEF2,HMG20B,RHEB,ARHGAP35,DPYSL3,GPRC5B,SEMA4D,BHLHB9,PTK7,LIMK1,TMEM30A,CSF1,NRG1,EFNA5,GPER1,RGS14,SOX8,ITPKA,ARSB,SEMA3A,COBL,L1CAM |
| 5.334e-03 | -5.23 | receptor tyrosine kinase binding | molecular function | GO:0030971 | 46 | 11 | 16491 | 1673 |
DOCK4,PLCG1,ELMO2,SHC3,PIK3R1,LRP4,TP53,NRG1,TOB1,ARHGEF16,SOCS5 |
| 5.348e-03 | -5.23 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | MSigDB lists | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | 47 | 11 | 17758 | 1761 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,NR3C2,RARG,NRBP1 |
| 5.348e-03 | -5.23 | CHIBA_RESPONSE_TO_TSA | MSigDB lists | CHIBA_RESPONSE_TO_TSA | 47 | 11 | 17758 | 1761 |
GRN,RHOA,CTGF,CYR61,IFITM3,H1F0,DHRS2,TMEM55B,SDC4,PRKRA,OPTN |
| 5.348e-03 | -5.23 | NADERI_BREAST_CANCER_PROGNOSIS_UP | MSigDB lists | NADERI_BREAST_CANCER_PROGNOSIS_UP | 47 | 11 | 17758 | 1761 |
KIF20A,ASPM,CDCA5,ATP2C2,PTTG1,NDC80,MYBL2,CDCA8,BUB1,CENPN,MELK |
| 5.349e-03 | -5.23 | Nuclear_hrmn_rcpt | interpro domains | IPR001723 | 47 | 11 | 18293 | 1814 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR2C1,NR2C2 |
| 5.363e-03 | -5.23 | chemorepellent activity | molecular function | GO:0045499 | 28 | 8 | 16491 | 1673 |
SEMA6B,SEMA4D,FLRT3,NRG1,EFNA5,SEMA3G,SEMA3A,SEMA3B |
| 5.365e-03 | -5.23 | autophagic cell death | biological process | GO:0048102 | 8 | 4 | 16441 | 1675 |
LAMP1,CDKN1B,CDKN2D,CTSV |
| 5.365e-03 | -5.23 | metanephric nephron tubule morphogenesis | biological process | GO:0072282 | 8 | 4 | 16441 | 1675 |
HES1,SOX8,LGR4,SOX9 |
| 5.365e-03 | -5.23 | response to water deprivation | biological process | GO:0009414 | 8 | 4 | 16441 | 1675 |
AKR1B1,LRP11,TFAP2A,CD9 |
| 5.365e-03 | -5.23 | interferon-gamma secretion | biological process | GO:0072643 | 8 | 4 | 16441 | 1675 |
BTN3A1,BTN3A2,RNF19B,F2RL1 |
| 5.365e-03 | -5.23 | negative regulation of phospholipid metabolic process | biological process | GO:1903726 | 8 | 4 | 16441 | 1675 |
PDGFA,SLC27A1,DAB2IP,PDGFB |
| 5.365e-03 | -5.23 | sulfate assimilation | biological process | GO:0000103 | 8 | 4 | 16441 | 1675 |
TXN,PAPSS2,SULT2B1,PAPSS1 |
| 5.365e-03 | -5.23 | glial cell apoptotic process | biological process | GO:0034349 | 8 | 4 | 16441 | 1675 |
CASP3,CASP9,TP53,BAX |
| 5.365e-03 | -5.23 | regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045091 | 8 | 4 | 16441 | 1675 |
TOP2A,APOBEC3H,APOBEC3D,APOBEC3G |
| 5.365e-03 | -5.23 | regulation of antimicrobial humoral response | biological process | GO:0002759 | 8 | 4 | 16441 | 1675 |
PPP2R3C,KLK7,KLK5,NOD2 |
| 5.365e-03 | -5.23 | protein localization to endosome | biological process | GO:0036010 | 8 | 4 | 16441 | 1675 |
PACSIN2,ACAP2,ARF6,TMEM30A |
| 5.365e-03 | -5.23 | cytoskeletal anchoring at nuclear membrane | biological process | GO:0090286 | 8 | 4 | 16441 | 1675 |
SUN1,SUN3,SUN2,SYNE2 |
| 5.372e-03 | -5.23 | MODULE_426 | MSigDB lists | MODULE_426 | 88 | 17 | 17758 | 1761 |
CYP26B1,ARAP2,SYBU,FTH1,LACTB2,NUCB2,PPP1R14C,ELF3,CNTNAP1,COL13A1,ACVRL1,AGBL5,TFAP2A,MAL2,TSPAN1,SHROOM2,IGSF3 |
| 5.372e-03 | -5.23 | KANG_IMMORTALIZED_BY_TERT_UP | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_UP | 88 | 17 | 17758 | 1761 |
PDGFC,COL6A2,CENPA,CTSZ,COL7A1,BCL2L1,PDGFB,LEPR,APPBP2,RHEB,SLC6A6,TJP3,ITGA3,P4HA2,CABP1,TFAP2A,CLMN |
| 5.374e-03 | -5.23 | neuron spine | cellular component | GO:0044309 | 109 | 20 | 17570 | 1756 |
EPHA4,GRIN1,FBXO2,PRKAR2B,SLC1A3,ARF4,GRM5,CDK5R1,ADORA1,PTEN,ANKS1B,SLC9A6,SIPA1L1,ARRB1,CTTN,GPER1,RGS14,ITPKA,NRGN,LZTS1 |
| 5.376e-03 | -5.23 | carbohydrate derivative catabolic process | biological process | GO:1901136 | 174 | 29 | 16441 | 1675 |
HMMR,ENPP4,HSPG2,GUSB,GNPDA1,HEXB,SDC4,CDA,FBXO2,PDE5A,APOBEC3H,FBXO6,SDC1,FUCA1,GNS,NUDT16,TYMP,NEIL1,HPSE,ABHD12,GALNS,AHCY,PDE4D,GLA,ARSB,APOBEC3G,NAGA,GM2A,CHP1 |
| 5.380e-03 | -5.23 | IDENTICAL_PROTEIN_BINDING | MSigDB lists | IDENTICAL_PROTEIN_BINDING | 300 | 44 | 17758 | 1761 |
S100A11,TRIP10,HEXB,ABCG2,ERBB2,BCL2L1,GPSM2,BARD1,SLC9A7,DAPK2,TOP2A,FOXP2,E2F7,CARD8,IGF1R,CST3,PASK,MAP3K9,BAX,CLDN4,ABCD1,OSTF1,ALS2CL,DVL2,S100A6,CCDC88A,AKT1,RGMB,CDA,CR2,EIF2AK1,SAV1,PSMA4,FAS,GNAS,PVRL2,NFKBIA,HDAC1,ANXA9,GLA,MAP3K5,USF2,NRBP1,ABCG1 |
| 5.384e-03 | -5.22 | Estrogen signaling pathway | WikiPathways | WP712 | 20 | 7 | 4455 | 516 |
GNAS,GPER1,AKT1,ELK1,FOS,PRKACA,PIK3CA |
| 5.386e-03 | -5.22 | PTB | pfam domains | PF08416 | 8 | 4 | 16629 | 1696 |
TNS3,TNS1,EPS8,EPS8L2 |
| 5.398e-03 | -5.22 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 163 | 27 | 17758 | 1761 |
PRKAA2,UNKL,THRB,CCNI,CHCHD7,BCL9,CXorf57,SELL,VWA1,NDRG2,TCF7,ERBB2IP,PSIP1,STK17A,PTPRF,IGF1R,MGAT4A,IL6ST,ANKFN1,FAM13B,CLIP4,TMOD2,TANC2,RCAN3,RAB27B,C9orf72,NR2C2 |
| 5.440e-03 | -5.21 | STK33_NOMO_DN | MSigDB lists | STK33_NOMO_DN | 259 | 39 | 17758 | 1761 |
EXPH5,MFSD3,ANXA3,LGR4,ST14,GALNT12,RET,SELL,PM20D2,CAMK1D,IL18R1,BEX2,NEO1,C16orf74,DOPEY2,SPIN4,MGAT4A,AIM1,PCYOX1,TMEM143,ZDHHC23,VAT1,ACOX2,EGLN3,RASGRP1,LAMP3,CDA,CR2,HEATR5A,ALCAM,FANCE,TCEAL8,CYP4F3,PLCH1,H1F0,MATN2,KLF5,CXorf56,NXT2 |
| 5.443e-03 | -5.21 | GCM_MAPK10 | MSigDB lists | GCM_MAPK10 | 81 | 16 | 17758 | 1761 |
MBP,TACC1,LRP4,NDRG2,SLC1A3,BBS2,NCS1,GPRC5B,ANKS1B,PHLPP2,DLG1,SERPINI1,TMOD2,BTBD3,CBX7,NIPA1 |
| 5.453e-03 | -5.21 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | 74 | 15 | 17758 | 1761 |
KLHL2,CD55,SWAP70,AIM1,EZR,ZNF165,ASAH1,NR4A2,IL13RA1,KLF9,DUSP4,C15orf39,ITPR3,ABCA1,GABARAPL1 |
| 5.473e-03 | -5.21 | antigen processing and presentation of exogenous peptide antigen via MHC class I | biological process | GO:0042590 | 79 | 16 | 16441 | 1675 |
SEC61B,PSMB4,HLA-E,PSME2,HLA-F,TAP1,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,TAPBP,HLA-B,PSMD1,HLA-C,ITGAV |
| 5.474e-03 | -5.21 | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | REACTOME pathways | R-HSA-1474151 | 12 | 5 | 8202 | 867 |
CALM2,CALM3,AKT1,SPR,CALM1 |
| 5.474e-03 | -5.21 | Activation of Ca-permeable Kainate Receptor | REACTOME pathways | R-HSA-451308 | 12 | 5 | 8202 | 867 |
CALM3,CALM2,DLG3,CALM1,DLG1 |
| 5.474e-03 | -5.21 | Ionotropic activity of Kainate Receptors | REACTOME pathways | R-HSA-451306 | 12 | 5 | 8202 | 867 |
CALM3,CALM2,DLG3,CALM1,DLG1 |
| 5.474e-03 | -5.21 | eNOS activation | REACTOME pathways | R-HSA-203615 | 12 | 5 | 8202 | 867 |
CALM2,CALM3,AKT1,CALM1,ZDHHC21 |
| 5.478e-03 | -5.21 | gastrulation | biological process | GO:0007369 | 159 | 27 | 16441 | 1675 |
EPB41L5,TNRC6C,NF2,TP53,COL7A1,ARFRP1,NCKAP1,DUSP4,NPHP3,PRKACA,COL12A1,MMP15,ITGA3,ETS2,TWSG1,FGFR2,PLPP3,ITGA7,DACT1,MEGF8,BMP7,ELF5,COL6A1,NR4A3,ITGAV,WNT3A,DVL2 |
| 5.478e-03 | -5.21 | WOOD_EBV_EBNA1_TARGETS_UP | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_UP | 110 | 20 | 17758 | 1761 |
GCLM,NQO1,S100A4,CALM1,TFAP2C,CALM3,NCKAP1,PRKRA,EMP2,FBLN1,LGALS3BP,H1FX,CALM2,GNAS,APOBEC3B,SLCO4A1,CTSC,OPN3,FHL1,ITGAV |
| 5.479e-03 | -5.21 | GOLUB_ALL_VS_AML_DN | MSigDB lists | GOLUB_ALL_VS_AML_DN | 23 | 7 | 17758 | 1761 |
PPIF,LGALS3,HOXA9,NFKBIA,CST3,CD33,FAH |
| 5.479e-03 | -5.21 | BIOCARTA_CELLCYCLE_PATHWAY | MSigDB lists | BIOCARTA_CELLCYCLE_PATHWAY | 23 | 7 | 17758 | 1761 |
CDKN1B,CCND1,CDKN2C,CCNB1,CDKN2D,RBL1,CDK1 |
| 5.479e-03 | -5.21 | ACTIN_FILAMENT_ORGANIZATION | MSigDB lists | ACTIN_FILAMENT_ORGANIZATION | 23 | 7 | 17758 | 1761 |
ARHGEF10L,EZR,SORBS1,NF2,SHROOM2,BCAR1,DLG1 |
| 5.479e-03 | -5.21 | MODULE_196 | MSigDB lists | MODULE_196 | 23 | 7 | 17758 | 1761 |
KIF23,CENPE,ARSB,MAP2,KIF11,SNTB2,KIF14 |
| 5.479e-03 | -5.21 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | 23 | 7 | 17758 | 1761 |
GEM,CPEB4,CSNK1G1,GNE,ETV5,HDAC9,RAB23 |
| 5.479e-03 | -5.21 | OSADA_ASCL1_TARGETS_DN | MSigDB lists | OSADA_ASCL1_TARGETS_DN | 23 | 7 | 17758 | 1761 |
KLF5,NRG1,IGFBP6,CDH1,AXL,SOCS3,CYP1B1 |
| 5.479e-03 | -5.21 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 23 | 7 | 17758 | 1761 |
MYL9,CALM2,CALM3,SORBS1,CALD1,MYL12B,CALM1 |
| 5.483e-03 | -5.21 | - | gene3d domains | 2.70.150.10 | 32 | 9 | 9988 | 1080 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 5.483e-03 | -5.21 | - | gene3d domains | 3.40.1110.10 | 32 | 9 | 9988 | 1080 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 5.483e-03 | -5.21 | LRP1 (LDL receptor related protein 1) | protein interactions | 4035 | 75 | 16 | 16036 | 1726 |
PLAUR,CD82,FURIN,FBXO6,PRKACA,PDGFB,RANBP9,MAPK8IP1,MMP15,MDK,CTGF,SERPINA1,ANKS1B,MMP17,WNT3A,SCN3A |
| 5.503e-03 | -5.20 | regulation of platelet activation | biological process | GO:0010543 | 28 | 8 | 16441 | 1675 |
PDGFA,SERPINE2,UBASH3B,PRKG1,PRKCQ,TEC,PDGFB,SYK |
| 5.503e-03 | -5.20 | mitotic cytokinesis | biological process | GO:0000281 | 28 | 8 | 16441 | 1675 |
PLK1,KIF20A,SNX18,CKAP2,KIF23,NUSAP1,ANLN,RASA1 |
| 5.507e-03 | -5.20 | positive regulation of mitotic nuclear division | biological process | GO:0045840 | 46 | 11 | 16441 | 1675 |
PLK1,DLGAP5,IGF1R,PTEN,CDCA5,RGCC,AURKA,NUSAP1,PDGFB,UBE2C,ESPL1 |
| 5.510e-03 | -5.20 | mesonephros development | biological process | GO:0001823 | 93 | 18 | 16441 | 1675 |
HES1,FMN1,RET,SOX9,SDC4,OSR2,SDC1,EPCAM,CTNNBIP1,FAT4,FGFR2,NPNT,BMP7,DLG1,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 5.521e-03 | -5.20 | viral entry into host cell | biological process | GO:0046718 | 86 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 5.523e-03 | -5.20 | APOPTOSIS_GO | MSigDB lists | APOPTOSIS_GO | 427 | 59 | 17758 | 1761 |
CASP3,BMF,DAP,TP53,BCL2L1,NCKAP1,AIFM2,GSTP1,BARD1,ADAMTSL4,TNFSF9,SGPL1,IER3,TOP2A,CDKN2C,DAPK2,CARD8,ADORA1,IGF1R,PTEN,SIVA1,DAPK1,BAX,BCL6,CDKN1B,CD70,PIM1,F2R,CDKN2D,MX1,AKT1,ACVR1C,GCLC,CASP9,HTATIP2,RUNX3,GLO1,BCAR1,STK17B,CDK1,CASP4,CDK5R1,RASA1,SOCS3,STK17A,FAS,SCG2,DNM1L,SEMA4D,MADD,NFKBIA,HDAC1,MAP3K5,HSPB1,AIFM3,IFI6,AHR,ESPL1,HIPK3 |
| 5.525e-03 | -5.20 | human chr22q13.1 | chromosome location | human chr22q13.1 | 82 | 13 | 26250 | 1887 |
SUN2,APOBEC3D,H1F0,SH3BP1,CBX6,TRIOBP,APOBEC3H,NPTXR,PDGFB,MAFF,CARD10,CBX7,HMGXB4 |
| 5.533e-03 | -5.20 | primary active transmembrane transporter activity | molecular function | GO:0015399 | 115 | 21 | 16491 | 1673 |
ATP8A1,ATP2C2,ABCG2,TAP1,SLC11A2,ATP1B1,ATP13A2,ABCD4,ATP6V0B,TAPBP,ATP1A1,ATP7B,ABCB1,ABCA2,PCYOX1,ABCD1,ATP1B3,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 5.533e-03 | -5.20 | P-P-bond-hydrolysis-driven transmembrane transporter activity | molecular function | GO:0015405 | 115 | 21 | 16491 | 1673 |
ATP8A1,ATP2C2,ABCG2,TAP1,SLC11A2,ATP1B1,ATP13A2,ABCD4,ATP6V0B,TAPBP,ATP1A1,ATP7B,ABCB1,ABCA2,PCYOX1,ABCD1,ATP1B3,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 5.538e-03 | -5.20 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1353 | 166 | 16441 | 1675 |
ACACB,LGR4,EPHA4,RET,CACNA2D2,IL18,CAMK1D,CCNB1,HDAC6,PDGFB,GRM5,CTGF,NPNT,IL6ST,CTTN,PACSIN1,TIAM1,RASGRP1,CYP1B1,NLRP4,ITCH,EZR,LOXL2,F12,POR,RHEB,DPYSL3,PLCG1,GPRC5B,HPSE,AGPAT2,LIMK1,NOD2,BMP1,ITPKA,HSPB1,F2RL1,DDX58,GRN,RUNX2,SERPINE2,LGALS3,HLA-E,SOX9,ETV5,IL18R1,ITGA3,CA2,CYR61,GATA2,MEGF8,FLRT3,SUCO,TNFRSF12A,MYDGF,WNT3A,RIMS2,SOCS5,EPB41L5,MMD,ANO6,HMG20B,PDE5A,EPHA1,GNAS,MAPKAPK2,NCOA3,SEMA4D,PLPP3,CSF1,TMEM30A,NFKBIA,AURKA,IFIH1,SEMA3A,TMEM173,FOXO6,HOXB7,IL15,INPP5D,IL27RA,CD274,OSR2,TNFSF9,SYTL2,PDGFA,CCND1,PLCG2,BCL6,DAB2IP,TWIST1,EPB41L4B,TMEM64,PDE4D,F2R,SULF2,ENPP4,TIMP2,AKT1,RIPK2,CDC20,PTGER4,PRKCQ,CD40,DAG1,ARHGAP35,ATP1A1,BHLHB9,AXL,PTK7,SLC27A1,NRG1,IRF7,EFNA5,RGS14,COBL,BIN1,WASF3,CTHRC1,ANXA3,NKX3-1,CRABP2,ETS1,SRPX2,TEAD3,SIX4,ADGRB2,HLA-A,NRP2,HDAC9,CTNNBIP1,CARD8,BMP7,TFAP2A,BAX,TRIM21,MAPK11,IQGAP3,CITED2,SYK,TLE6,TGIF1,HES1,RHOA,RAPGEF2,ASPM,PIK3R1,RGCC,FOS,BBS2,BCAR1,GPLD1,CD83,ACVRL1,FGFR2,TBX18,DTX4,NR4A3,ERAP1,PPP2R3C,GPER1,OSR1,FZD5,SOX8,ARSB,L1CAM |
| 5.561e-03 | -5.19 | PROTEIN_DIMERIZATION_ACTIVITY | MSigDB lists | PROTEIN_DIMERIZATION_ACTIVITY | 179 | 29 | 17758 | 1761 |
CLCN3,S100A11,HEXB,TAP1,ABCG2,TP53,CDA,ERBB2,TFAP2C,CR2,EIF2AK1,BARD1,SLC9A7,TOP2A,FOXP2,CARD8,PVRL2,CST3,MAP3K9,BAX,TFAP2A,ANXA9,ERBB3,GLA,MAP3K5,NRBP1,S100A6,CCDC88A,ABCG1 |
| 5.561e-03 | -5.19 | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | 179 | 29 | 17758 | 1761 |
GCLM,CDK17,LGALS3,DAP,DGKQ,EPHA4,IL13RA1,PRKAR2B,FANCE,FAS,WEE1,FAM64A,STK38,CABP1,TCEAL4,POF1B,TLE1,STK39,NOTCH3,GRAMD1C,LGMN,FAIM,TBC1D4,TRIM62,MAFF,OCLN,SMAGP,KLF7,XKR8 |
| 5.561e-03 | -5.19 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | 179 | 29 | 17758 | 1761 |
UGP2,TNIP1,IL15RA,RIPK2,RAPGEF2,SDC4,IL18,CD274,SLC1A3,SAV1,RNF19B,CDK1,CD83,SOCS3,IER3,BTG3,E2F7,PTPRJ,TMEM54,ITGB8,PIK3AP1,SNX18,NFKBIA,SLC2A6,RAP2C,DRAM1,ARRB1,NFKBIZ,EHD1 |
| 5.561e-03 | -5.19 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | 179 | 29 | 17758 | 1761 |
DDX58,SLC35D2,SORT1,PRSS23,NQO1,EPS8,SERTAD3,IL13RA1,GDF15,TRIB2,PHLDA1,DDR1,FZD7,DGKE,OPTN,IL17RB,ZFYVE16,PLCG1,HLF,ADD3,CYP1A1,CA2,H1F0,DRAM1,IRF7,FAR2,HSPB1,F2RL1,AHR |
| 5.562e-03 | -5.19 | WEST_ADRENOCORTICAL_TUMOR_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_UP | 284 | 42 | 17758 | 1761 |
SLC25A24,CDK17,TXN,FOXM1,TMEM41B,CNOT8,PTTG1,SLC1A3,CCNB1,ERP29,SLC20A1,BARD1,FANCI,TOP2A,KIF5B,ATP6V0B,HSF2,ELMO2,KIF14,NEK2,RPN2,BUB1,EPB41L4B,ABCC1,ZWINT,KIF20A,ASPM,PBK,GGH,GLO1,ICMT,CDK1,ATP1A1,TMEM30A,P4HA2,HOXA9,SLC2A6,AURKA,HDAC1,ESPL1,ACOT7,MELK |
| 5.590e-03 | -5.19 | galactosyltransferase activity | molecular function | GO:0008378 | 34 | 9 | 16491 | 1673 |
B3GALT6,B3GALNT1,B3GNT7,UGT8,B3GNT2,A4GALT,C1GALT1C1,B4GALT4,PLOD3 |
| 5.590e-03 | -5.19 | Progesterone-mediated oocyte maturation | KEGG pathways | hsa04914 | 87 | 18 | 6908 | 758 |
PLK1,CPEB4,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,PRKACA,CDK1,RPS6KA2,IGF1R,PIK3CA,BUB1,MAPK11,PIK3CD,CCNB2,CPEB2,MAPK12 |
| 5.590e-03 | -5.19 | Progesterone-mediated oocyte maturation | KEGG pathways | ko04914 | 87 | 18 | 6908 | 758 |
PLK1,CPEB4,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,PRKACA,CDK1,RPS6KA2,IGF1R,PIK3CA,BUB1,MAPK11,PIK3CD,CCNB2,CPEB2,MAPK12 |
| 5.594e-03 | -5.19 | V$ICSBP_Q6 | MSigDB lists | V$ICSBP_Q6 | 235 | 36 | 17758 | 1761 |
CCDC109B,SORBS1,PARP12,CPEB4,HOXB7,KLHL13,TAP1,ERBB2,OSR2,TNFRSF19,SCML1,DTX3L,CDKN2C,CXCL16,FRY,ATP5H,MGAT4A,RRBP1,FUT8,DUSP10,TWIST1,ARMCX6,DDB2,TGIF1,RIPK2,CITED4,USP18,SYNE2,SLC11A2,ITPR3,IFIT3,TAPBP,BANK1,ITPR1,IFIH1,ZBTB33 |
| 5.604e-03 | -5.18 | Diseases of signal transduction | REACTOME pathways | R-HSA-5663202 | 268 | 42 | 8202 | 867 |
PSME2,HDAC11,PSMD10,ERBB2,NRG2,TGFBR1,PSME1,HDAC6,PDGFB,KREMEN1,FGF19,ZFYVE9,FZD6,HDAC9,PDGFA,PSMD1,CNTRL,PIK3CA,CDKN1B,ERBB3,PIK3CD,WNT3A,HES1,ERLEC1,AKT1,PSMB4,FZD4,NR4A1,PIK3R1,CASP9,AMER1,MAML2,NEURL1B,PSMA4,IRS2,PLCG1,PPP2R5A,FGFR2,HDAC1,NRG1,FZD5,GAB1 |
| 5.612e-03 | -5.18 | GSE27786_LSK_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD8_TCELL_UP | 187 | 30 | 17758 | 1761 |
B3GALT6,CASP3,SHMT1,TXN,ST14,STAU2,SLC25A13,CBX6,CCDC34,CDCA2,CCNF,DHRS3,GLCE,PRDX4,METTL7A,MATN2,SGK3,BMP1,PLEKHF1,AURKA,VAT1,RELL1,IQGAP3,TMEM159,CITED2,PTPRE,TBC1D4,C12orf75,COL16A1,E2F8 |
| 5.612e-03 | -5.18 | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | 187 | 30 | 17758 | 1761 |
COL9A3,PHF20L1,CMAS,SCN5A,PQLC3,TBC1D1,IQGAP1,USP18,SYNE2,C3orf52,ITPR2,HERC6,FAM101B,RASGRP2,E2F7,ADD3,PPP2R5A,KLF3,SGK1,ABCD1,IRF7,OSTF1,IFIT1,PIEZO1,ARSB,TRAF5,F2RL1,IFIH1,ALS2CL,GM2A |
| 5.612e-03 | -5.18 | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | 187 | 30 | 17758 | 1761 |
GAA,HES1,SLC2A4,PODXL2,ALDH2,ENO2,CITED4,CORO2A,SERTAD4,PLEKHO1,LMCD1,PRKAR2B,TDRKH,FOS,RNPEP,C11orf95,ADRBK2,LRRC42,ALDH3B1,SLCO4A1,NUCB1,KCNK1,TSPAN6,SH3BP4,SGK1,ALDH7A1,LRRK1,ARMCX6,EGLN3,CNPY3 |
| 5.612e-03 | -5.18 | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | 187 | 30 | 17758 | 1761 |
SLC35D2,CDK17,TNIP1,PLAUR,RAPGEF2,STAT4,DNAJC3,CASP9,LITAF,HTATIP2,SRPX2,OPTN,MDK,MMP15,CDH1,JAK1,CYR61,TIMM8A,SH3BP1,OSBPL3,NFKBIA,SRR,INPP4B,AKR1B1,TWIST1,NRG1,ITPKA,DRP2,PTGES,EHD1 |
| 5.612e-03 | -5.18 | MEK_UP.V1_DN | MSigDB lists | MEK_UP.V1_DN | 187 | 30 | 17758 | 1761 |
DDX58,CYP26B1,COL9A3,ARMCX3,ZNF84,USP18,LPGAT1,CALB2,TAP1,PRKAR2B,F12,HERC6,SP100,IGF1R,SLC16A6,PTER,ALG13,LRIG1,INPP4B,ATP8B1,IRF7,IFIT1,ANXA9,OAS3,MINPP1,IFIH1,SNX10,MYBL1,IFI6,RASGRP1 |
| 5.612e-03 | -5.18 | GSE14308_TH2_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH2_VS_INDUCED_TREG_UP | 187 | 30 | 17758 | 1761 |
NUDT6,ARAP3,ASPM,SH3BGRL,EPS8,PTTG1,PBX3,PRSS22,RAD17,SPNS3,AIP,PLS3,BCAR3,CCDC92,IRS2,HS6ST1,JAK1,AGPAT2,KIAA1107,OSBPL3,SIPA1L1,FAM13B,ECI2,ERAP1,YOD1,SP6,NCEH1,ARPC2,LRIF1,SPRY2 |
| 5.628e-03 | -5.18 | CCTGCTG,MIR-214 | MSigDB lists | CCTGCTG,MIR-214 | 227 | 35 | 17758 | 1761 |
CPEB4,TRIP10,FAM134A,HMGN3,TGOLN2,RAB15,PIK3AP1,ANKS1B,DOK4,RIMS3,VASN,LHX6,ARVCF,CRY2,PIM1,NPTXR,ING1,CELSR2,ITCH,OXR1,PANK1,GRIN1,TFAP2C,VEZT,FAM133B,PELI3,GALNT7,SNX12,FZD7,PGF,DOLPP1,CSF1,PTER,RGMA,DOCK9 |
| 5.632e-03 | -5.18 | mitotic cell cycle | biological process | GO:0000278 | 802 | 104 | 16441 | 1675 |
CCNE2,SPC25,CEP70,DLGAP5,FOXM1,PSME2,ACTR8,PTTG1,NDC80,TP53,NUF2,PSME1,BCL2L1,CCNB1,PRKACA,STIL,CENPN,FANCI,IER3,CDKN2C,CCND1,WEE1,PSMD1,SETDB2,CNTRL,KIF14,CEP78,DLG1,PLK4,TUBG1,CDKN1B,CDKN2D,PLK1,CENPA,PBK,CDC20,PRKAR2B,NUSAP1,CDCA2,PKMYT1,RAD17,CCNF,ANLN,CDK1,OPTN,PRIM1,RBL1,PLK2,PRDM5,TRIOBP,HDAC1,KLF11,RGS14,REEP4,E2F8,PPP2R2D,CKAP2,KLHL13,CENPI,CIT,EPS8,CDCA8,PSMD10,KIF23,GPSM2,LMNA,SAC3D1,TOP2A,E2F7,SNX18,PTEN,NEK2,BUB1,IQGAP3,SPRY2,NUP85,SUN2,ZWINT,RHOA,KIF20A,PSMB4,ASPM,MYBL2,KIF11,BORA,PSMA4,RASA1,DCTN6,FAM64A,CDCA5,ABCB1,FAM83D,AURKA,CENPE,GEM,CEP41,WDR62,NDE1,NCAPG2,UBE2C,CCNB2,NUP58,ESPL1,MELK |
| 5.645e-03 | -5.18 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 195 | 31 | 17758 | 1761 |
LAMP1,MBP,DNAJB2,SNTB2,TP53,ARL4C,SELL,SLC11A2,KCTD12,TCF7,FAM101B,FOS,SESN1,FAM46C,SOCS3,SIPA1L2,TAPBP,ETS2,NR1D2,LMO4,ZFP36,FOSB,SLC44A1,SORL1,FAM102A,ARRB1,NFKBIZ,PIM1,TOB1,NR2C1,ABCG1 |
| 5.645e-03 | -5.18 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | 195 | 31 | 17758 | 1761 |
RMND5A,SYPL1,MTM1,RPS6KA1,S100A4,STAT4,GGH,MGST2,DHRS3,DDR1,SIRPA,B4GALNT1,FAM46A,CDK16,METTL7A,SEMA4D,DPYSL2,ITGA7,FAM13B,AIM1,KLF3,ABCB1,NEK2,OSTF1,ZRANB1,CNOT6L,RGS14,LTA4H,UBE2C,S100A6,GCNT1 |
| 5.645e-03 | -5.18 | GSE17721_CTRL_VS_LPS_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDM_DN | 195 | 31 | 17758 | 1761 |
CPD,PMPCB,GOLIM4,IL15RA,CRYM,CD82,TAP1,DNAJB11,KLK6,DNER,SPTLC2,REPS1,KREMEN1,KIAA1161,RAD23A,RPS6KA2,ADRBK1,PVRL2,GDE1,TMEM30A,PLK2,RANBP1,HDAC1,KLF5,SLC27A1,CITED2,SNX10,SLC25A38,C9orf72,PPP2R2D,JARID2 |
| 5.645e-03 | -5.18 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 31 | 17758 | 1761 |
MAP3K3,CPD,SORBS1,RUNX2,IL15,CAMKK1,SNTB2,TSC22D3,NUB1,SERTAD3,IL13RA1,MGST2,LDB2,CARD10,SFXN5,GALNT3,ATP6V0B,DOPEY2,IGF1R,PIK3AP1,ARSG,BCL6,IRF2,IFIT1,PIM1,C10orf54,MAP3K5,MYLIP,SPRY2,CKAP4,XKR8 |
| 5.645e-03 | -5.18 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | 195 | 31 | 17758 | 1761 |
GRN,GCA,TIMP2,MCTP1,LGALS3,S100A11,SAT1,HEXB,ASAH1,KCTD12,NPC2,SIRPA,GNS,TNS3,APLP2,SERPINA1,SLC16A6,CORO1C,PLCG2,CST3,DAPK1,PPM1H,NOD2,BCL6,MTMR11,ZMIZ1,SLC27A3,PTPRE,SYK,CKAP4,CD33 |
| 5.658e-03 | -5.17 | TNF (tumor necrosis factor) | protein interactions | 7124 | 102 | 20 | 16036 | 1726 |
CPD,LAMP2,CELSR2,TNIP1,RALBP1,HSPA12A,PDIK1L,TNFSF9,DAG1,SFXN5,RHEB,OPTN,NEO1,FAS,CSF1,ZFP36,MMP17,BDH1,NFKBIA,HSPB1 |
| 5.667e-03 | -5.17 | regulation of cation transmembrane transport | biological process | GO:1904062 | 167 | 28 | 16441 | 1675 |
PPIF,SCN5A,KCNIP3,FXYD3,CALM1,UTRN,CALM3,ATP1B1,PRKACA,CACNB4,WWP2,CALM2,SNTA1,GNB5,STIM1,CABP1,PLCG2,DLG1,FXYD5,CAB39,TSPAN13,STK39,PDE4D,ATP1B3,FHL1,CACNA1D,MYO5A,CHP1 |
| 5.699e-03 | -5.17 | ITGA5 (integrin alpha 5) | protein interactions | 3678 | 38 | 10 | 16036 | 1726 |
ATP1A1,FGFR2,CD9,COL18A1,ERBB2,GRK6,FBXO6,ATP1B3,L1CAM,LGALS3BP |
| 5.700e-03 | -5.17 | UDP_GLYCOSYLTRANSFERASE_ACTIVITY | MSigDB lists | UDP_GLYCOSYLTRANSFERASE_ACTIVITY | 41 | 10 | 17758 | 1761 |
GALNT3,B3GALNT1,UGT8,MGAT4A,XYLT1,MGAT4B,GALNT7,POMGNT1,B4GALNT1,GCNT1 |
| 5.701e-03 | -5.17 | Kinesin_motor_CS | interpro domains | IPR019821 | 41 | 10 | 18293 | 1814 |
KIF5B,KIF20A,KIFC2,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 5.747e-03 | -5.16 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | GO:0070059 | 34 | 9 | 16441 | 1675 |
DNAJC10,ITPR1,ERO1A,BAX,TMBIM6,SELK,DAB2IP,MAP3K5,CASP4 |
| 5.747e-03 | -5.16 | T cell homeostasis | biological process | GO:0043029 | 34 | 9 | 16441 | 1675 |
CASP3,AKT1,SIVA1,RC3H2,BAX,PPP2R3C,CCNB2,JAK3,FAS |
| 5.768e-03 | -5.16 | ESTABLISHMENT_OF_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_LOCALIZATION | 860 | 108 | 17758 | 1761 |
SLC2A4,SORBS1,RALBP1,SLC25A13,TP53,ARFGEF1,SLC7A2,BCL2L1,SYTL4,ERP29,CACNB4,SLC20A1,BARD1,ZFYVE9,SYTL2,APPBP2,ABCD4,ZFYVE16,ATP6V0B,SCNN1A,AP1M2,CDH1,STIM1,REEP1,SLC44A1,STEAP2,ABCA2,BCL6,KCNS3,TRPC1,TINAGL1,SCN2A,ARL4D,LMAN1,F2R,TRAM1,ATG4D,SEC23A,AKT1,COG2,HTATIP2,KIF1C,SLC11A2,NUSAP1,ICMT,SLC25A5,OPTN,EDNRA,KCNMB4,SLC25A4,KCNK1,ATP7B,CORO1C,NOD2,ARF6,ABCA1,LASP1,SCN5A,ARAP3,NFKBIE,GGA1,PEX6,FXYD3,ABCG2,PDIA3,SLC1A3,AIP,PDIA4,ATG4A,M6PR,KIF5B,DOPEY2,CARD8,ADORA1,GATA2,SLC16A6,KIF13B,KCNN4,BAX,SLC44A2,SORL1,SGK1,CACNA1D,SLC16A5,KDELR1,ABCC1,MDFI,SUN2,KCNJ12,ZWINT,KIF20A,PPARA,STRADB,NPC2,MAPK8IP1,KLHL2,SCG2,CDCA5,SH3BP4,ABCB1,CTSA,LTBP2,CENPE,PLIN3,ARSB,SHROOM2,NRBP1,ABCG1 |
| 5.769e-03 | -5.16 | IRS2 (insulin receptor substrate 2) | protein interactions | 8660 | 50 | 12 | 16036 | 1726 |
PTPRF,SIRT1,PLCG1,IGF1R,JAK1,PIK3R1,PIK3CA,PIK3CD,BCL2L1,JAK3,DVL2,SOCS3 |
| 5.778e-03 | -5.15 | MODULE_175 | MSigDB lists | MODULE_175 | 54 | 12 | 17758 | 1761 |
SNTA1,LTBP1,IGF1R,IL15RA,TRIP10,SEMA4D,COG2,PLOD2,CR2,COL18A1,PHLDA1,ARHGAP35 |
| 5.778e-03 | -5.15 | GNF2_ITGAL | MSigDB lists | GNF2_ITGAL | 54 | 12 | 17758 | 1761 |
DDX58,SUN2,SIGIRR,ARHGEF3,JAK1,SEMA4D,HLA-F,STK38,ARL4C,BTN3A2,BTN3A1,RASGRP1 |
| 5.778e-03 | -5.15 | REACTOME_ION_CHANNEL_TRANSPORT | MSigDB lists | REACTOME_ION_CHANNEL_TRANSPORT | 54 | 12 | 17758 | 1761 |
ATP1A1,ATP9A,ATP7B,ATP8A1,ATP2C2,GABRG2,ATP8B1,ATP8B3,ATP1B1,ATP1B3,ATP10D,ARHGEF9 |
| 5.783e-03 | -5.15 | skin-malignant_melanoma-nodular | COSMIC cancer mutations | skin-malignant_melanoma-nodular | 29 | 8 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 5.783e-03 | -5.15 | pancreas-carcinoid-endocrine_tumour-insulinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-insulinoma | 29 | 8 | 17775 | 1757 |
GNAS,CDKN2C,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2 |
| 5.783e-03 | -5.15 | autonomic_ganglia-adrenal_gland-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-adrenal_gland-neuroblastoma | 29 | 8 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,ERBB2,IDH1 |
| 5.783e-03 | -5.15 | insulinoma | COSMIC cancer mutations | insulinoma | 29 | 8 | 17775 | 1757 |
GNAS,CDKN2C,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2 |
| 5.794e-03 | -5.15 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 35 | 9 | 17775 | 1757 |
KIF5B,SS18,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1 |
| 5.805e-03 | -5.15 | PROGRAMMED_CELL_DEATH | MSigDB lists | PROGRAMMED_CELL_DEATH | 428 | 59 | 17758 | 1761 |
CASP3,BMF,DAP,TP53,BCL2L1,NCKAP1,AIFM2,GSTP1,BARD1,ADAMTSL4,TNFSF9,SGPL1,IER3,TOP2A,CDKN2C,DAPK2,CARD8,ADORA1,IGF1R,PTEN,SIVA1,DAPK1,BAX,BCL6,CDKN1B,CD70,PIM1,F2R,CDKN2D,MX1,AKT1,ACVR1C,GCLC,CASP9,HTATIP2,RUNX3,GLO1,BCAR1,STK17B,CDK1,CASP4,CDK5R1,RASA1,SOCS3,STK17A,FAS,SCG2,DNM1L,SEMA4D,MADD,NFKBIA,HDAC1,MAP3K5,HSPB1,AIFM3,IFI6,AHR,ESPL1,HIPK3 |
| 5.805e-03 | -5.15 | ear morphogenesis | biological process | GO:0042471 | 115 | 21 | 16441 | 1675 |
CTHRC1,SOX9,SCRIB,OSR2,PRKRA,SIX4,ABR,FZD6,FGFR2,GATA2,PTK7,LRIG1,TBX18,ALDH1A3,NR4A3,TFAP2A,TWIST1,WNT3A,OSR1,SPRY2,DVL2 |
| 5.812e-03 | -5.15 | MODULE_16 | MSigDB lists | MODULE_16 | 497 | 67 | 17758 | 1761 |
EPAS1,FOXM1,S100A11,INPP5D,RPS6KA1,PTTG1,NDC80,NRG2,SDC1,CARD10,IER3,CDKN2C,DAPK2,WEE1,ARTN,SH3BP1,PLCG2,IFIT1,CKS2,CYP1B1,CPD,PLK1,LAMP2,CENPA,PTPRU,S100A4,CDC20,CDA,ARHGDIB,PKMYT1,CCNF,AGPAT2,BMP1,GLA,ITGA6,DCAF7,PKN1,M6PR,CTNNBIP1,TOP2A,LLGL2,CTSC,TBCD,BDH1,CITED2,GPR161,HMMR,FADS2,ZWINT,PLAUR,MYBL2,GGH,TCF7,KIF11,RNPEP,PSMA4,CDK5R1,MMP15,SLC6A6,NMI,DTX4,ZMIZ1,UBE2C,SERPINB1,ESPL1,JARID2,CD33 |
| 5.828e-03 | -5.15 | human chr2q36.1 | chromosome location | human chr2q36.1 | 11 | 4 | 26250 | 1887 |
MRPL44,SERPINE2,ARPC2,EPHA4 |
| 5.871e-03 | -5.14 | INTEGRAL_TO_MEMBRANE | MSigDB lists | INTEGRAL_TO_MEMBRANE | 1271 | 153 | 17758 | 1761 |
LAMP1,BCAM,SLC25A13,EPHA4,SLC20A1,SDC1,SLC9A7,GRM5,ABCD4,HTR1D,STIM1,IL6ST,SLC44A1,STEAP2,FUT1,ABCA2,TRPC1,CLDN4,TACSTD2,TRAM1,SGCE,CD55,MCTP1,ACVR1C,ROR1,SLC25A5,EDNRA,ENPP1,HS6ST1,KCNMB4,SLC25A4,KCNK1,GDE1,DOLPP1,ATP7B,MADD,F2RL1,CD99,FXYD3,ABCG2,B4GALT4,MERTK,TSPAN7,ITGA3,KCNN4,SLC16A6,OPN3,FXYD5,SORL1,CD70,NCAM1,SLC12A2,CKAP4,KDELR1,ABCC1,FADS2,PODXL2,PCDH1,MMD,MFI2,EPHA1,STEAP1,PTPRF,MMP15,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,ATP1B3,SLC2A4,IL15,ST14,CD82,PKP2,IL27RA,IL13RA1,SLC7A2,EMP2,DDR1,BCAP31,ATP6V0B,VAT1,NOTCH3,EPHB4,ECE1,LMAN1,TSPAN1,F2R,CLCN3,PTPRU,FZD4,PTGER4,IGSF8,SLC11A2,ATP1B1,CD40,DAG1,FZD7,TAPBP,PTPRJ,ATP1A1,MMP17,WFS1,AXL,SLC9A6,PTK7,PEX2,SECTM1,HS3ST3B1,LIFR,ABCA1,GOLIM4,TSPAN15,CD63,SELL,GABRG2,CYB561,TGFBR1,SBF1,EFNB1,LBR,FZD6,SLC9A2,M6PR,NEO1,IL17RB,ADORA1,ITGB8,BAX,SLC44A2,TMBIM6,TSPAN13,ERBB3,SGCB,SLC16A5,ATP2B1,GCNT1,SYPL1,MPP1,AMFR,GRIN1,CD83,CNTNAP1,GALNT3,ACVRL1,SPINT2,ABCB1,RYK,PGRMC1,FZD5,GOLGB1,CD33 |
| 5.883e-03 | -5.14 | follicular_carcinoma | COSMIC cancer mutations | follicular_carcinoma | 61 | 13 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 5.883e-03 | -5.14 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | 61 | 13 | 17775 | 1757 |
GNAS,PCDH1,CDH1,AKT1,ALPP,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 5.883e-03 | -5.14 | Langerhans_cell_histiocytosis | COSMIC cancer mutations | Langerhans_cell_histiocytosis | 61 | 13 | 17775 | 1757 |
GNAS,PCDH1,CDH1,AKT1,ALPP,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 5.883e-03 | -5.14 | thyroid-carcinoma-follicular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-follicular_carcinoma | 61 | 13 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 5.904e-03 | -5.13 | N-glycan antennae elongation in the medial/trans-Golgi | REACTOME pathways | R-HSA-975576 | 22 | 7 | 8202 | 867 |
MAN2A2,FUCA1,B4GALT4,MGAT4A,MGAT5,FUT8,MGAT4B |
| 5.904e-03 | -5.13 | Cyclin A/B1 associated events during G2/M transition | REACTOME pathways | R-HSA-69273 | 22 | 7 | 8202 | 867 |
PLK1,WEE1,PKMYT1,CCNB1,FOXM1,CCNB2,CDK1 |
| 5.916e-03 | -5.13 | ENDOPLASMIC_RETICULUM | MSigDB lists | ENDOPLASMIC_RETICULUM | 285 | 42 | 17758 | 1761 |
PDIA5,PDIA3,DNAJB11,CTSZ,ITPR2,DSE,ERP29,DNAJB9,PDIA4,RCN1,ARSG,STIM1,BAX,TMBIM6,RPN2,MINPP1,LMAN1,PDIA6,TRAM1,ERAP2,CCDC88A,SEMA3B,SEC23A,SEC61B,AMFR,ACO1,KIF1C,PKMYT1,ITPR3,ICMT,POR,TAPBP,AGPAT2,DDOST,PLOD2,DNM1L,DOLPP1,SLC9A6,ERAP1,CTSA,PLOD3,AIFM3 |
| 5.918e-03 | -5.13 | DORSAM_HOXA9_TARGETS_UP | MSigDB lists | DORSAM_HOXA9_TARGETS_UP | 35 | 9 | 17758 | 1761 |
ARHGAP11A,MAN2A2,ADD3,ETS2,SERINC2,DHX8,PIM1,YES1,CTH |
| 5.988e-03 | -5.12 | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | MSigDB lists | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | 236 | 36 | 17758 | 1761 |
MRC2,KLHL13,PSME2,HLA-F,TAP1,FBXO2,ASB9,PDIA3,PSMD10,RNF182,PSME1,FBXO6,PJA2,HLA-A,DTX3L,PSMD1,UBE2Q2,RNF220,UBE2J1,TRIM21,WWP1,HLA-C,SEC23A,SEC61B,PSMB4,CDC20,UBE2A,ASB13,PSMA4,SOCS3,TRIM9,HLA-B,ERAP1,ITGAV,FBXO27,UBE2C |
| 5.988e-03 | -5.12 | V$P300_01 | MSigDB lists | V$P300_01 | 236 | 36 | 17758 | 1761 |
CDK17,ZNF395,HEBP1,CAST,TSC22D3,BCL2L1,SIX4,ANKS1B,TSPAN6,DPYSL2,BHLHE41,LHX6,SLC44A1,ADAM15,TWIST1,TNFRSF12A,PIK3CD,CCDC88A,RBMS2,FURIN,ERBB2IP,BORA,RASGRP2,GPLD1,EPN3,PRKAG2,SLC9A6,NFKBIA,SERPINI1,SP6,RGS14,ARF6,FZD5,C1orf43,RARG,JARID2 |
| 6.030e-03 | -5.11 | RGS3 (regulator of G-protein signaling 3) | protein interactions | 5998 | 27 | 8 | 16036 | 1726 |
SCN5A,PLSCR1,RGS3,ARRB1,HIPK3,EFNB1,GNA11,MAPK12 |
| 6.032e-03 | -5.11 | soft_tissue-blood_vessel-haemangioma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma | 18 | 6 | 17775 | 1757 |
PLCG1,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 6.032e-03 | -5.11 | endometrium-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-clear_cell_carcinoma | 18 | 6 | 17775 | 1757 |
AKT1,FGFR2,PTEN,PIK3R1,PIK3CA,TP53 |
| 6.032e-03 | -5.11 | fibroblastic | COSMIC cancer mutations | fibroblastic | 18 | 6 | 17775 | 1757 |
CDKN2C,ERBB2,NF2,AKT1,PTEN,PIK3CA |
| 6.032e-03 | -5.11 | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | MSigDB lists | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | 228 | 35 | 17758 | 1761 |
PEX6,RALBP1,ARL4C,ABCG2,DHX8,MRAS,RAB6A,ABCD4,DIRAS3,TOP2A,ABCA2,ATP8B1,RAB27B,ARL4D,ATP2B1,ABCC1,RAB3B,RHOA,ARFRP1,ATP1B1,PIF1,GNA11,ARF4,RHEB,GNAS,TAPBP,ENPP1,ATP1A1,RND3,DNM1L,ATP7B,DOLPP1,ATP1B3,ARF6,ABCG1 |
| 6.040e-03 | -5.11 | Choline metabolism in cancer | KEGG pathways | hsa05231 | 101 | 20 | 6908 | 758 |
PLA2G4A,WASF3,PDGFC,AKT1,DGKQ,PIK3R1,PDGFB,FOS,RHEB,DGKE,PDGFA,DGKH,PLCG1,PLPP3,SLC44A1,PIK3CA,SLC44A2,PLD1,PIK3CD,DGKG |
| 6.040e-03 | -5.11 | Choline metabolism in cancer | KEGG pathways | ko05231 | 101 | 20 | 6908 | 758 |
PLA2G4A,WASF3,PDGFC,AKT1,DGKQ,PIK3R1,PDGFB,FOS,RHEB,DGKE,PDGFA,DGKH,PLCG1,PLPP3,SLC44A1,PIK3CA,SLC44A2,PLD1,PIK3CD,DGKG |
| 6.042e-03 | -5.11 | SWEET_KRAS_ONCOGENIC_SIGNATURE | MSigDB lists | SWEET_KRAS_ONCOGENIC_SIGNATURE | 89 | 17 | 17758 | 1761 |
LGALS3,IL18,TGOLN2,PDK3,NPC2,ATP1B1,SLC25A5,PHLDA1,SIRPA,GNS,CCND1,CST3,MANF,CITED2,SLC12A2,KDELR1,MDFI |
| 6.044e-03 | -5.11 | LEE_LIVER_CANCER_ACOX1_UP | MSigDB lists | LEE_LIVER_CANCER_ACOX1_UP | 61 | 13 | 17758 | 1761 |
RPL12,PLSCR1,NQO1,ETS2,CD63,SGK1,HTATIP2,HDAC1,IGFBP2,TAGLN2,SLC20A1,LGALS3BP,GPX4 |
| 6.044e-03 | -5.11 | LEE_LIVER_CANCER_MYC_TGFA_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_TGFA_UP | 61 | 13 | 17758 | 1761 |
CCND1,BTG3,RPL12,IGFBP6,PLSCR1,ETS2,CD63,USP18,AKR1B1,HTATIP2,TAGLN2,CYP39A1,ELF3 |
| 6.044e-03 | -5.11 | MODULE_254 | MSigDB lists | MODULE_254 | 61 | 13 | 17758 | 1761 |
BCAR3,PLK1,MX1,WEE1,LGALS3,DNAJC3,CDC20,MYBL2,BCL2L1,CCNB1,STK17B,FAS,IER3 |
| 6.061e-03 | -5.11 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | 188 | 30 | 17758 | 1761 |
GRN,ALDH2,IFITM3,SALL4,AASS,MPP1,ATP8A1,PLAUR,CR2,IL18,ITPR2,ERP29,RNPEP,LGALS3BP,NUCB1,SIPA1L2,FAM64A,STIM1,NEK2,ARRB1,CTSA,PLD1,TMEM37,MAP3K5,RGS14,PLOD3,PTPRE,SYK,SMAGP,KDELR1 |
| 6.061e-03 | -5.11 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | 188 | 30 | 17758 | 1761 |
B3GNT2,SPC25,TNIP1,PBK,ITCH,ABCG2,DNAJB11,IL18,FTH1,F11R,CAMK1D,GPSM2,STK17B,KREMEN1,CDK1,ARHGAP24,SLC4A4,RNF128,FAM13B,SLC44A1,MADD,OPN3,UBE2J1,TMEM51,CLMN,HDAC1,MRPS28,ACSL4,PLD1,SMYD5 |
| 6.061e-03 | -5.11 | GSE17721_CTRL_VS_LPS_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDM_UP | 188 | 30 | 17758 | 1761 |
CCNI,SEC61B,SPC25,GUSB,GNPDA1,CKAP2,PBK,MBNL3,ABCG2,TESK2,KIF1C,TGFBR1,MRAS,KIF13A,NANS,ERBB2IP,MGST2,FAM81A,CDK1,MDM1,IL6ST,BDH1,NR4A3,ADAM15,ABCD1,CTSA,PLD1,CCNB2,MED22,GPX4 |
| 6.061e-03 | -5.11 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | 188 | 30 | 17758 | 1761 |
SUN2,ORAI2,SLC37A1,TNIP1,ARMC7,ARL4C,VWA1,YES1,KCTD2,DOCK5,SEPP1,SLC20A1,SESN1,HLA-A,GNS,PLCG1,PPP2R5A,JAK1,NR1D2,STK38,TRAF3IP1,KLF3,PGM2L1,CDKN1B,FAM117A,SGK1,C10orf54,TOB1,RASGRP1,ABCG1 |
| 6.061e-03 | -5.11 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 188 | 30 | 17758 | 1761 |
CD99,LZTFL1,MRPS33,HJURP,CAST,PLEKHO1,SDC4,HABP4,ERBB2,CYB561,IL27RA,INTS8,RAD17,TRIB2,ITPR3,DHRS3,SESN1,STEAP1,LTBP3,ABCD4,TMEM63A,TOP2A,ADD3,IL6ST,PASK,PIK3C2B,DLG3,TRAM1,HSPB1,DOCK9 |
| 6.061e-03 | -5.11 | GSE13306_TREG_VS_TCONV_SPLEEN_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_DN | 188 | 30 | 17758 | 1761 |
PCDH1,SLC39A8,SEPT6,HSPA12A,NFE2L1,CYB561,DSE,SLC20A1,ERP29,MNS1,GNA11,SH3KBP1,LGALS3BP,SP4,SYTL2,AHRR,TFAP4,OTUD1,DUOX1,SESN3,CDH1,SIVA1,CYP2S1,PGM2L1,SORL1,TRPC1,HS3ST3B1,CTDSP2,AHR,ALDH3A2 |
| 6.061e-03 | -5.11 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | 188 | 30 | 17758 | 1761 |
NFE2L3,TXN,SEC61B,PPP1R2,MRPS15,PSME2,DAP,DNAJC3,ITCH,USP18,TAP1,HTATIP2,NDUFA4,RAD17,ICMT,SLC25A5,MYL12A,PSMA4,FAS,LRRC42,MSL1,WFS1,NOD2,AKR1B1,TLE1,CTSA,SPCS3,TRAM1,ISOC1,RASGRP1 |
| 6.065e-03 | -5.11 | KONDO_EZH2_TARGETS | MSigDB lists | KONDO_EZH2_TARGETS | 220 | 34 | 17758 | 1761 |
ARHGEF3,TRIM2,ATP9A,ITGA6,LMCD1,IL13RA1,DNER,ANO1,CTGF,GALNS,KLF3,AOX1,ATP8B1,SORL1,SGK1,NTN4,KLF9,SCN2A,FAR2,LMAN1,SLC12A2,DOCK4,TMTC1,RAB3B,RGMB,SNTB2,STMN3,IFIT3,HLF,FHL1,OSR1,ST3GAL1,IFI6,RRAGD |
| 6.086e-03 | -5.10 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 196 | 31 | 17758 | 1761 |
LTBP1,TIMP2,NQO1,PLAUR,FAM134A,SLC11A2,TCF7,IL27RA,FOS,GNA11,KIAA1161,BSDC1,SGPL1,AKIRIN1,MMP15,ST5,RPL12,RPS6KA2,CA2,COQ10A,RALGPS2,NR1D2,SH3BP1,NR4A3,SORL1,NOTCH3,ST3GAL1,F2RL1,NAGA,JARID2,ABCG1 |
| 6.086e-03 | -5.10 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | 196 | 31 | 17758 | 1761 |
IER5L,MRPL44,MBP,CENPA,DAP,LPGAT1,HABP4,ACO1,TP53,NUF2,GLO1,MGST2,HDAC6,SESN1,FRMD4B,ANKRD10,RBM47,NR1D2,LIMK1,CDCA7L,NR4A3,FAM117A,ARRB1,MDH1,CENPE,IQGAP3,CNOT6L,CCNB2,MYL12B,CPPED1,GPX4 |
| 6.086e-03 | -5.10 | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | MSigDB lists | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | 196 | 31 | 17758 | 1761 |
PLA2G4A,LAMP2,RHOA,AKT1,CD63,DGKQ,CALM1,PIK3R1,HABP4,CALM3,PRKCQ,ITPR2,ITPR3,BCAR1,PDGFB,GNA11,DGKE,RASGRP2,DGKH,CALM2,PDGFA,SERPINA1,GNB5,PLCG2,PIK3CA,CD9,ARRB1,F2R,DGKG,SYK,RASGRP1 |
| 6.086e-03 | -5.10 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | 196 | 31 | 17758 | 1761 |
MX1,TIMP2,COL6A2,PAPSS2,NQO1,ATP9A,FAM134A,PPFIBP2,SP4,BSDC1,SOX13,SGPL1,AKIRIN1,NCOA3,ST5,RPL12,CA2,COQ10A,RALGPS2,CNTRL,ACVRL1,COL6A1,NR4A3,BCL6,ABCD1,TMEM159,USF2,F2RL1,NAGA,JARID2,ABCG1 |
| 6.086e-03 | -5.10 | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDM_UP | 196 | 31 | 17758 | 1761 |
MX1,TGIF1,ARMCX3,PLSCR1,MMD,STAT4,FAM133B,YES1,RAB38,PKMYT1,FOS,STK17B,LTBP3,KREMEN1,GALNT3,IRS2,RCN1,ETS2,BFSP1,GRHL1,RND3,KBTBD2,BHLHE41,KLF3,SH3BP4,AOX1,TLE1,NFKBIZ,MDFIC,KLF9,SYT13 |
| 6.086e-03 | -5.10 | NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY | MSigDB lists | NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY | 212 | 33 | 17758 | 1761 |
PEX6,RALBP1,ARL4C,ABCG2,DHX8,MRAS,RAB6A,ABCD4,DIRAS3,TOP2A,ABCA2,ATP8B1,RAB27B,ARL4D,ATP2B1,ABCC1,RAB3B,RHOA,ARFRP1,ATP1B1,PIF1,GNA11,ARF4,RHEB,GNAS,TAPBP,ATP1A1,RND3,DNM1L,ATP7B,ATP1B3,ARF6,ABCG1 |
| 6.089e-03 | -5.10 | Glycogen breakdown (glycogenolysis) | REACTOME pathways | R-HSA-70221 | 17 | 6 | 8202 | 867 |
CALM2,CALM3,GAA,PGM1,PHKA2,CALM1 |
| 6.114e-03 | -5.10 | NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) | protein interactions | 4790 | 152 | 27 | 16036 | 1726 |
TXN,NFKBIE,TNIP1,NR3C1,NR4A1,TSC22D3,CD82,CUL4B,PSMD10,NKRF,PRKACA,FOS,ETS1,PSMA4,ELF3,SOCS3,NOV,NCOA3,ZFP36,NFKBIA,AURKA,IRF2,HDAC1,KLF5,NFKBIZ,HMGA1,RGS14 |
| 6.122e-03 | -5.10 | RNF mutants show enhanced WNT signaling and proliferation | REACTOME pathways | R-HSA-5340588 | 8 | 4 | 8202 | 867 |
FZD5,WNT3A,FZD4,FZD6 |
| 6.122e-03 | -5.10 | Negative regulation of the PI3K/AKT network | REACTOME pathways | R-HSA-199418 | 8 | 4 | 8202 | 867 |
PHLPP1,AKT1,PTEN,PHLPP2 |
| 6.125e-03 | -5.10 | stomach-carcinoma-mucinous_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-mucinous_adenocarcinoma | 13 | 5 | 17775 | 1757 |
ERBB2,PTEN,PIK3R1,PIK3CA,TP53 |
| 6.125e-03 | -5.10 | mucinous_adenocarcinoma | COSMIC cancer mutations | mucinous_adenocarcinoma | 13 | 5 | 17775 | 1757 |
ERBB2,PTEN,PIK3R1,PIK3CA,TP53 |
| 6.128e-03 | -5.09 | Furin_repeat | interpro domains | IPR006212 | 18 | 6 | 18293 | 1814 |
ERBB2,ERBB3,IGF1R,FRAS1,PCSK5,FURIN |
| 6.129e-03 | -5.09 | CHEN_PDGF_TARGETS | MSigDB lists | CHEN_PDGF_TARGETS | 18 | 6 | 17758 | 1761 |
GOT1,KLF9,ZFAND5,TIPARP,LMNA,SGPL1 |
| 6.129e-03 | -5.09 | SMID_BREAST_CANCER_LUMINAL_A_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_A_DN | 18 | 6 | 17758 | 1761 |
TOP2A,CENPN,CDC20,NDC80,MYBL2,CDCA8 |
| 6.129e-03 | -5.09 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | 18 | 6 | 17758 | 1761 |
GALNT3,EGFL7,CDH1,CYR61,FXYD3,NCS1 |
| 6.129e-03 | -5.09 | BIOCARTA_PTEN_PATHWAY | MSigDB lists | BIOCARTA_PTEN_PATHWAY | 18 | 6 | 17758 | 1761 |
CDKN1B,AKT1,PTEN,BCAR1,PIK3R1,PIK3CA |
| 6.129e-03 | -5.09 | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | MSigDB lists | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | 18 | 6 | 17758 | 1761 |
GALNT3,ACSL4,NPNT,KCNN4,CD82,WBP5 |
| 6.129e-03 | -5.09 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | MSigDB lists | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | 18 | 6 | 17758 | 1761 |
PRKAA2,CAB39,STRADB,ACACB,PRKAG2,CPT2 |
| 6.129e-03 | -5.09 | ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 18 | 6 | 17758 | 1761 |
SUN2,NUSAP1,CENPE,AP1M2,SHROOM2,CDCA5 |
| 6.146e-03 | -5.09 | kinesin complex | cellular component | GO:0005871 | 54 | 12 | 17570 | 1756 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KLC3,KIF23,KIF1C,KIF13A,CENPE,NDE1,KIF11 |
| 6.155e-03 | -5.09 | MITOSIS | MSigDB lists | MITOSIS | 82 | 16 | 17758 | 1761 |
PLK1,ZWINT,CIT,NDC80,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDCA5,NEK2,AURKA,BUB1,CENPE,UBE2C,ESPL1 |
| 6.155e-03 | -5.09 | HOOI_ST7_TARGETS_UP | MSigDB lists | HOOI_ST7_TARGETS_UP | 82 | 16 | 17758 | 1761 |
ANXA3,PCGF5,ACACB,RUNX2,KIAA1462,IL15,RGMB,CDA,ISOC2,ENDOD1,IL6ST,IL31RA,LHX6,INPP4B,FHL1,CYP2U1 |
| 6.179e-03 | -5.09 | nerve_sheath | COSMIC cancer mutations | nerve_sheath | 48 | 11 | 17775 | 1757 |
GNAS,SS18,NF2,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11 |
| 6.179e-03 | -5.09 | ENK_UV_RESPONSE_KERATINOCYTE_DN | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_DN | 481 | 65 | 17758 | 1761 |
GAS2L1,RGS20,ARFGEF1,SP100,BCL6,CDKN1B,GOT1,RP2,IFIT1,LAMP3,LAMP2,CPD,SEC23A,SMARCA2,CELSR2,SNTB2,SLC11A2,DUSP4,H2AFV,SLC25A5,ZFAND5,SLC9A6,HOXA9,NRG1,SERPINE2,PEX6,GNE,DHRS3,LBR,FZD6,TFAP4,TOP2A,DOPEY2,RRBP1,GTF2F2,SORL1,KLF9,MYO5A,SNX7,IGSF3,SYPL1,HES1,ZWINT,PLSCR1,TACC1,MICB,YES1,FOS,STEAP1,RASA1,BCAR3,NCOA3,ACADSB,RND3,H1F0,NMI,ERAP1,MDH1,ATP1B3,MAP3K5,UBE2C,COL16A1,AFAP1,ARHGEF4,KLF7 |
| 6.182e-03 | -5.09 | centriole | cellular component | GO:0005814 | 103 | 19 | 17570 | 1756 |
POC1B,CCSAP,CCNF,NUBP1,STIL,NIN,CEP162,DZIP1L,TOP2A,CCDC92,PLK2,PLK4,TUBG1,AURKA,RP2,CEP41,CFAP20,WDR62,MPHOSPH9 |
| 6.182e-03 | -5.09 | hormone-mediated signaling pathway | biological process | GO:0009755 | 94 | 18 | 16441 | 1675 |
THRB,NKX3-1,NR3C1,NR4A1,THRA,PPARA,NR1D2,BMP7,NR4A3,ADIPOR1,NR4A2,SLC27A1,GPER1,NR3C2,NR2C1,RARG,PAQR7,NR2C2 |
| 6.206e-03 | -5.08 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | 75 | 15 | 17758 | 1761 |
GNS,CCNE2,GPRC5B,CDKN1C,HLA-E,MICB,NAT1,TMBIM6,IFIT1,OSR2,NPTXR,TP53I3,TNFSF9,TOB1,GABARAPL1 |
| 6.210e-03 | -5.08 | regulation of JUN kinase activity | biological process | GO:0043506 | 80 | 16 | 16441 | 1675 |
FZD4,EPHA4,PKN1,GSTP1,MAP3K6,MAP3K9,DUSP10,MDFIC,DAB2IP,MAP3K5,FZD5,HIPK3,GAB1,SYK,DVL2,MDFI |
| 6.211e-03 | -5.08 | Peptidase_C1A | interpro domains | IPR013128 | 13 | 5 | 18293 | 1814 |
CTSL,CTSZ,TINAGL1,CTSC,CTSV |
| 6.211e-03 | -5.08 | APOBEC/CMP_deaminase_Zn-bd | interpro domains | IPR016192 | 13 | 5 | 18293 | 1814 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 6.211e-03 | -5.08 | Peptidase_C1A_C | interpro domains | IPR000668 | 13 | 5 | 18293 | 1814 |
CTSL,CTSZ,TINAGL1,CTSC,CTSV |
| 6.211e-03 | -5.08 | VACUOLAR_TRANSPORT | MSigDB lists | VACUOLAR_TRANSPORT | 13 | 5 | 17758 | 1761 |
ZFYVE16,ARSB,ATG4D,M6PR,ATG4A |
| 6.211e-03 | -5.08 | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | MSigDB lists | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | 13 | 5 | 17758 | 1761 |
TNS1,LTBP2,FRMD4A,DSE,CALD1 |
| 6.211e-03 | -5.08 | TSAI_DNAJB4_TARGETS_UP | MSigDB lists | TSAI_DNAJB4_TARGETS_UP | 13 | 5 | 17758 | 1761 |
IFIT1,TIMP3,OAS3,IFIT3,SERPINB1 |
| 6.211e-03 | -5.08 | MODULE_143 | MSigDB lists | MODULE_143 | 13 | 5 | 17758 | 1761 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 6.211e-03 | -5.08 | WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP | MSigDB lists | WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP | 13 | 5 | 17758 | 1761 |
TLE1,ANXA3,PLOD2,PLK2,MYEOV |
| 6.211e-03 | -5.08 | HASINA_NOL7_TARGETS_UP | MSigDB lists | HASINA_NOL7_TARGETS_UP | 13 | 5 | 17758 | 1761 |
CD99,CD70,TIMP2,PLAUR,NEO1 |
| 6.211e-03 | -5.08 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP | 13 | 5 | 17758 | 1761 |
ATP8B1,TCF7,HSPB1,DPYSL2,RGS20 |
| 6.211e-03 | -5.08 | EXTRINSIC_TO_PLASMA_MEMBRANE | MSigDB lists | EXTRINSIC_TO_PLASMA_MEMBRANE | 13 | 5 | 17758 | 1761 |
GNAS,ARRB1,SYTL4,APC2,SYTL2 |
| 6.226e-03 | -5.08 | entry into cell of other organism involved in symbiotic interaction | biological process | GO:0051806 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.226e-03 | -5.08 | movement in host environment | biological process | GO:0052126 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.226e-03 | -5.08 | entry into host cell | biological process | GO:0030260 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.226e-03 | -5.08 | entry into other organism involved in symbiotic interaction | biological process | GO:0051828 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.226e-03 | -5.08 | movement in environment of other organism involved in symbiotic interaction | biological process | GO:0052192 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.226e-03 | -5.08 | negative regulation of viral process | biological process | GO:0048525 | 87 | 17 | 16441 | 1675 |
MX1,TRIM8,PLSCR1,TNIP1,APOBEC3D,IFITM3,APOBEC3H,FBLN1,TFAP4,FAM111A,SP100,TRIM21,HDAC1,OAS3,IFIT1,APOBEC3G,TRIM62 |
| 6.226e-03 | -5.08 | establishment of cell polarity | biological process | GO:0030010 | 87 | 17 | 16441 | 1675 |
CENPA,FRMD4A,ARHGEF11,NDC80,EZR,SCRIB,MPP5,GPSM2,FRMD4B,WEE1,IGF1R,LLGL2,RAB11FIP2,PTK7,ARF6,NDE1,SPRY2 |
| 6.226e-03 | -5.08 | entry into host | biological process | GO:0044409 | 87 | 17 | 16441 | 1675 |
LAMP1,PVRL4,CD55,ITCH,CR2,F11R,DAG1,WWP2,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1 |
| 6.233e-03 | -5.08 | Colorectal cancer | KEGG pathways | ko05210 | 62 | 14 | 6908 | 758 |
CCND1,CASP3,RHOA,AKT1,PIK3R1,CASP9,TP53,BAX,PIK3CA,TGFBR1,TCF7,PIK3CD,APC2,FOS |
| 6.233e-03 | -5.08 | Colorectal cancer | KEGG pathways | hsa05210 | 62 | 14 | 6908 | 758 |
CCND1,CASP3,RHOA,AKT1,PIK3R1,CASP9,TP53,BAX,PIK3CA,TGFBR1,TCF7,PIK3CD,APC2,FOS |
| 6.236e-03 | -5.08 | SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1) | protein interactions | 6654 | 63 | 14 | 16036 | 1726 |
BIN1,PLCG1,SORBS1,NF2,SNX18,EPS8,ERBB2,ERBB3,LRRK1,PACSIN1,GAB1,RANBP9,EPS8L2,SH3KBP1 |
| 6.236e-03 | -5.08 | PRKCG (protein kinase C, gamma) | protein interactions | 5582 | 63 | 14 | 16036 | 1726 |
DDX58,TOP2A,ADRBK1,HABP4,GRIN1,GRIN2D,NRGN,TIAM1,RANBP9,AFAP1,DVL2,GRM5,SCN3A,OCLN |
| 6.260e-03 | -5.07 | positive regulation of cell cycle | biological process | GO:0045787 | 311 | 46 | 16441 | 1675 |
NKX3-1,DLGAP5,CIT,PSME2,CUL4B,TP53,KIF23,PSMD10,PSME1,CCNB1,PRKACA,PDGFB,STIL,CCND1,E2F7,CYP1A1,PSMD1,CTGF,IGF1R,PTEN,KIF14,PLK4,CDKN1B,TRIM21,DAB2IP,PIM1,CITED2,PLK1,HES1,RHOA,AKT1,PSMB4,RGCC,NUSAP1,PSMA4,CDK5R1,NUDT16,FGFR2,CDCA5,NR4A3,FAM83D,AURKA,OVOL1,UBE2C,E2F8,ESPL1 |
| 6.269e-03 | -5.07 | CAIRO_HEPATOBLASTOMA_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_DN | 253 | 38 | 17758 | 1761 |
SIGIRR,ACACB,PAPSS2,UGP2,AASS,CPT2,HAL,GNE,NDRG2,SLC20A1,ANO1,CYP39A1,CYP26A1,CA2,FAM46A,CYP4F11,SORL1,FAM102A,GOT1,CTH,PRODH,SHMT1,OGDHL,CDA,ZFAND5,LEPR,ARHGEF26,GPLD1,MFAP3L,ETS2,AGPAT2,FAAH,RND3,DHTKD1,NRG1,GRAMD1C,MAP3K5,XDH |
| 6.274e-03 | -5.07 | WTTGKCTG_UNKNOWN | MSigDB lists | WTTGKCTG_UNKNOWN | 490 | 66 | 17758 | 1761 |
LTBP1,REPS2,SLC25A13,MORF4L2,NANS,APC2,CYP26A1,CDH1,PRICKLE3,TMEM143,ANKRD12,CDKN1B,DAB2IP,DIXDC1,RP2,NOTCH3,DLG3,MYT1,TIAM1,MAP3K3,CAPN6,COQ10B,SERTAD3,SLC11A2,ATP1B1,MRPS36,SLC25A4,HOXA9,NKD1,TLE1,KLF11,NR2C2,RMND5A,IER5L,SORT1,PDIA3,TRIB2,CRABP2,C3orf18,TEAD3,HDAC9,TMCC3,FOXP2,FRY,CDK16,ANKS1B,FRAS1,CALD1,SELK,NCAM1,MDFI,C9orf9,DPYSL5,HES1,PHF20L1,PIK3R1,NFIB,PRX,FAM83D,ETAA1,NDE1,IFIH1,SEMA3A,UBE2C,TLL2,KLF7 |
| 6.288e-03 | -5.07 | human chrXq21.33 | chromosome location | human chrXq21.33 | 6 | 3 | 26250 | 1887 |
DIAPH2,SYTL4,DIAPH2-AS1 |
| 6.288e-03 | -5.07 | human chr18p11.3 | chromosome location | human chr18p11.3 | 6 | 3 | 26250 | 1887 |
TGIF1,TWSG1,RALBP1 |
| 6.289e-03 | -5.07 | transferase activity, transferring hexosyl groups | molecular function | GO:0016758 | 200 | 32 | 16491 | 1673 |
UGT8,GALNT12,XYLT1,HEXB,MGAT5B,POMGNT1,B4GALT4,CHPF,B4GALNT1,B3GALNT1,TYMP,FUT2,A4GALT,MGAT4A,ALG13,XYLT2,FUT8,FUT1,RPN2,MGAT5,GCNT1,B3GALT6,CHSY3,B3GNT7,B3GNT2,MGAT4B,GYLTL1B,C1GALT1C1,GALNT7,GALNT3,DDOST,PLOD3 |
| 6.301e-03 | -5.07 | BLALOCK_ALZHEIMERS_DISEASE_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_DN | 1209 | 146 | 17758 | 1761 |
GAA,TXN,MRPS15,CRYM,EPHA4,HEXB,OAT,CALM2,EPCAM,PSMD1,HSF2,ELMO2,SHC3,CABP1,PHTF1,PAPSS1,TRPC1,PTPRE,SMARCA2,SH3BGRL,PRKAR2B,LDB2,SLC25A5,RHEB,ARF4,DNM1L,KCNK1,PLK2,CAB39,ADIPOR1,MRPS28,SERPINI1,ITPKA,NRGN,LZTS1,MYL12B,CDK17,PPP1R2,ASAH1,CALM3,NDUFA4,CNTNAP2,RAB6A,COX6C,HPCAL4,TSPAN7,B4GALNT1,ATP5H,RFX5,GAD1,RIMS2,MCCC2,FAM69A,CYP26B1,PMPCB,MMD,OXR1,CALM1,EIF2AK1,RANBP9,CDK5R1,GNAS,FECH,ETS2,UAP1,ITPR1,SLC4A3,PITPNA,MDH1,ARPC2,TMEM14A,RUSC1,DYNLRB1,NQO1,UGP2,NF2,RGS20,FAM198B,SNN,NOV,APLP2,ZNF75D,LMO4,RPN2,GOT1,PDE4D,IFIT1,SCN2A,PDIA6,SNX10,CDKN2D,NR2C1,SCN3A,CKS2,SEPT6,DRAP1,SAT1,PTGER4,GLO1,ATP1B1,GTF2A2,H2AFV,ATP13A2,ALDH5A1,DDOST,NGFRAP1,AXL,SLC9A6,RGS14,ARHGEF3,PINK1,ENO2,ARL4C,PSMD10,AES,DNAJB9,DIRAS3,CCDC92,PTEN,CDK16,TMBIM6,TSPAN13,ATP2B1,DLGAP1,PGM1,ALDH2,PSMB4,MPP1,AMFR,UBE2A,STMN3,MAPK8IP1,PRDX4,DCTN6,FUCA1,HLA-B,SPINT2,ABCB1,NETO2,PGRMC1,FHL1,NDFIP1,L1CAM,ARHGEF9,ACOT7,ARHGEF4 |
| 6.303e-03 | -5.07 | SANSOM_APC_TARGETS_DN | MSigDB lists | SANSOM_APC_TARGETS_DN | 353 | 50 | 17758 | 1761 |
CASP3,PCOLCE,RUNX2,PAPSS2,GNPDA1,CPT2,INPP5D,CD82,COL18A1,IL18,COL4A5,MGST2,MERTK,SIRPA,DNAJB9,GNS,ATP6V0B,ITGA3,MLPH,CYP2S1,CD70,ABCD1,PIK3CD,MYH14,PTPRE,SULT2B1,CDKN2D,S100A13,GPX4,LPGAT1,NUB1,PLEKHO1,PPARA,SLC11A2,ARHGDIB,ATP1B1,MCFD2,TP53INP2,CYP4F3,GNA11,ABR,CYB5A,FAS,CNTNAP1,HLA-B,SLC4A4,TOB1,XDH,PCSK5,RRAGD |
| 6.310e-03 | -5.07 | MODULE_317 | MSigDB lists | MODULE_317 | 404 | 56 | 17758 | 1761 |
LMTK3,FAM169A,CDH22,AASS,MRPS15,TP53,SLC25A27,C6orf106,CTSZ,ISYNA1,NANS,IL18R1,CMTM6,C9orf69,CYP1A1,RNF220,CDK16,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,CNOT6L,FAIM,FAR2,CITED2,ATG4D,AMOTL2,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,PTPRF,AMZ2,FUCA1,NEIL1,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,PKIA,RRAGD |
| 6.321e-03 | -5.06 | RUIZ_TNC_TARGETS_DN | MSigDB lists | RUIZ_TNC_TARGETS_DN | 134 | 23 | 17758 | 1761 |
CCNE2,ZWINT,HJURP,SPC25,SERPINE2,FOXM1,PBK,RGS20,BARD1,CDK1,FANCI,PRIM1,PTPRF,FAM111A,SH3BP4,TNFRSF12A,NRG1,NCAPG2,MYBL1,UBE2C,E2F8,MELK,CKS2 |
| 6.323e-03 | -5.06 | CELLULAR_PROTEIN_METABOLIC_PROCESS | MSigDB lists | CELLULAR_PROTEIN_METABOLIC_PROCESS | 1099 | 134 | 17758 | 1761 |
CASP3,SIGIRR,SSH1,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,DAPK2,IL31RA,FUT1,DUSP10,RP2,PTPRE,METAP2,TNIP1,GALNT7,LOXL2,ANLN,ICMT,STK17B,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,BMP1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,PEX6,DNAJB2,MERTK,TSPAN7,RABGGTA,ATG4A,B3GALNT1,IGF1R,PAIP2B,RPL39,TBCD,MAP3K9,DAPK1,TPST1,PRKG1,PIM1,MYLIP,GAD1,CCDC88A,DDB2,MGAT4B,STRADB,EIF2AK1,NUBP1,RASA1,GLCE,STK17A,MAPKAPK2,MMP15,AURKA,JAK3,NF2,ST14,HDAC11,PDIA5,TESK2,ERBB2,ZFYVE9,CCND1,PLK4,RPN2,LMAN1,PHKA2,PDIA6,F2R,ATG4D,SEPHS1,MAP3K3,SIRT1,AKT1,COG2,PTPRU,PTPN9,CDC20,DUSP4,MAP3K6,CASP4,IDE,PTPRJ,STK38,NRG1,HS3ST3B1,MAPK12,WASF3,PINK1,CTSZ,TGFBR1,FBXO6,POMGNT1,SBF1,TRIB2,PKN1,AIP,PPP2R3A,WWP2,FUT2,CDK16,PTEN,MGAT4A,FUT8,RRBP1,SGK3,SGK1,WWP1,ERBB3,GCNT1,AMFR,UBE2A,FURIN,PARP4,YES1,PRDX4,PLOD2,ACVRL1,NR4A3,ERAP1,HMGA1,PLOD3,UBE2C,HIPK3,ABCG1 |
| 6.330e-03 | -5.06 | GNF2_PTPN6 | MSigDB lists | GNF2_PTPN6 | 48 | 11 | 17758 | 1761 |
HLA-B,TAPBP,ACAP2,HLA-E,HLA-F,FXYD5,SELL,ARHGDIB,GRK6,HLA-C,HLA-A |
| 6.330e-03 | -5.06 | FAELT_B_CLL_WITH_VH3_21_DN | MSigDB lists | FAELT_B_CLL_WITH_VH3_21_DN | 48 | 11 | 17758 | 1761 |
ING1,MICB,LMO4,PBX3,ASAH1,PSMD10,CDKN1B,NPC2,IFI6,CTDSP2,CBX7 |
| 6.339e-03 | -5.06 | extracellular matrix binding | molecular function | GO:0050840 | 47 | 11 | 16491 | 1673 |
BCAM,ITGA3,LGALS3,CYR61,ADGRG1,LYPD3,ITGA7,NTN4,ITGAV,TINAGL1,DAG1 |
| 6.339e-03 | -5.06 | acetylglucosaminyltransferase activity | molecular function | GO:0008375 | 47 | 11 | 16491 | 1673 |
B3GNT2,XYLT2,ALG13,MGAT4A,XYLT1,MGAT4B,HEXB,MGAT5B,POMGNT1,MGAT5,GCNT1 |
| 6.355e-03 | -5.06 | mating behavior | biological process | GO:0007617 | 23 | 7 | 16441 | 1675 |
THRB,GRN,APLP2,PTEN,THRA,HEXB,GRIN1 |
| 6.355e-03 | -5.06 | negative regulation of microtubule depolymerization | biological process | GO:0007026 | 23 | 7 | 16441 | 1675 |
AURKA,GAS2L1,MID1IP1,CCNB1,HDAC6,CKAP2,APC2 |
| 6.361e-03 | -5.06 | positive regulation of innate immune response | biological process | GO:0045089 | 295 | 44 | 16441 | 1675 |
DDX58,LAMP1,RPS6KA1,HLA-E,PSME2,CALM3,PSMD10,PSME1,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,PIK3AP1,PLCG2,MAPK11,LGMN,SCARA3,CNPY3,SYK,RASGRP1,SMAGP,PLSCR1,PSMB4,TNIP1,RIPK2,ITCH,CALM1,DUSP4,ITPR3,ELK1,FOS,PSMA4,CTSL,MAPKAPK2,PVRL2,PELI2,NFKBIA,ITPR1,NOD2,NLRC5,IRF7,IFIH1,TMEM173 |
| 6.370e-03 | -5.06 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | 165 | 27 | 17758 | 1761 |
SUSD3,CD55,CHCHD7,HAPLN3,ITGA6,SELL,STRADB,EPHA1,C3orf18,HPCAL4,SFXN5,SCML1,IGF1R,NGFRAP1,IL6ST,BDH1,PASK,SPINT2,TPST1,SOX8,CEP41,NDFIP1,NR3C2,PKIA,KLF7,ARHGEF4,PCSK5 |
| 6.422e-03 | -5.05 | glial cell projection | cellular component | GO:0097386 | 13 | 5 | 17570 | 1756 |
AKR1B1,EZR,PINK1,ADGRG1,GRM5 |
| 6.422e-03 | -5.05 | condensed chromosome outer kinetochore | cellular component | GO:0000940 | 13 | 5 | 17570 | 1756 |
PLK1,BUB1,CENPE,CCNB1,NDC80 |
| 6.426e-03 | -5.05 | positive regulation of lymphocyte proliferation | biological process | GO:0050671 | 116 | 21 | 16441 | 1675 |
HES1,CD55,RIPK2,IL15,HLA-E,IL18,PRKCQ,CD274,CD40,TNFSF9,EFNB1,HLA-A,IRS2,IL6ST,BCL6,IGFBP2,SLC39A10,ICOSLG,WNT3A,JAK3,SYK |
| 6.426e-03 | -5.05 | developmental growth involved in morphogenesis | biological process | GO:0060560 | 116 | 21 | 16441 | 1675 |
EPB41L5,EMX1,FMN1,IQGAP1,SOX9,TFAP2C,ALCAM,NRP2,FGFR2,PTK7,FLRT3,SLC9A6,CSF1,AURKA,EFNA5,WNT3A,SEMA3A,SLC12A2,SPRY2,COBL,RARG |
| 6.432e-03 | -5.05 | DODD_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_DN | 1265 | 152 | 17758 | 1761 |
IL15RA,GNPDA1,SLC25A13,NDC80,PLXNA1,CCNB1,CENPN,FANCI,BTG3,UBE2T,NPNT,DPYSL2,CEP78,SLC44A1,SLC39A10,LAMP2,CENPA,PBK,USP18,CCNF,ANLN,LHFPL2,IDH1,CDK1,RHEB,PRIM1,MSL1,DNM1L,ZNF367,DHTKD1,STARD3NL,DDX58,PARP12,FRMD4A,HJURP,NUAK1,ASB9,KIF23,SLC1A3,CNTNAP2,GPSM2,PM20D2,FRAS1,RANBP1,NEK2,AHCY,GAD1,NUP85,MPHOSPH9,MCCC2,CKAP4,SOCS5,MMD,ZNF84,KIF20A,ANO6,VEZT,IFIT3,ANKRD29,PSMA4,FAS,FAM64A,CDCA5,FGD6,AURKA,DONSON,ZDBF2,NDE1,CCNB2,IFIH1,AFAP1,EGLN1,CCNE2,ARHGAP11A,FOXO6,DLGAP5,PAPSS2,UPF3B,IL15,FOXM1,PTTG1,MORC4,NUF2,CD274,FAM198B,RCN1,NOV,KIF14,PLK4,RPN2,OAS3,EPHB4,ACSL4,LMAN1,MINPP1,F2R,SNX10,SEPHS1,CKS2,PPIF,DOCK4,GCA,RIPK2,FIGNL1,PANK1,NUSAP1,CDCA2,ZNF618,FZD7,RBL1,NGFRAP1,AXL,TLE1,TM2D2,DEPDC1,CKAP2,CENPI,INTS8,POMGNT1,NTAN1,ARHGEF40,TIPRL,HMGXB4,SAC3D1,SCML1,SLC25A36,TOP2A,PTEN,CTSC,CALD1,FJX1,DRAM1,GTF2F2,BUB1,IQGAP3,NFE2L3,B3GALT6,HMMR,ADAMTS2,ZWINT,ZC3H11A,ASPM,EIF5A2,C2orf69,KIF11,CRISPLD2,TWSG1,ITGAV,CENPE,NCAPG2,UBE2C,MELK |
| 6.443e-03 | -5.04 | peptidyl-amino acid modification | biological process | GO:0018193 | 929 | 118 | 16441 | 1675 |
IL15,P3H2,EPHA4,RET,TESK2,ERBB2,NANS,MORF4L2,CCNB1,HDAC6,PRKACA,PDGFB,DDR1,WEE1,RPS6KA2,SP100,SETDB2,ZDHHC12,ZDHHC23,RPN2,EPHB4,LMAN1,EGLN3,F2R,MGAT5,METAP2,CTH,PLK1,PPIF,SIRT1,SEC23A,RIPK2,AKT1,ROR1,MCFD2,CDK1,POR,EPHA10,PIAS3,JADE1,MAN2A2,MSL1,JAK1,DDOST,P4HA2,DOLPP1,PTK7,AXL,PRDM5,ST3GAL1,MAPK12,PRKAA2,CMAS,PINK1,GNE,PDIA3,TGFBR1,CTSZ,RAB6A,TEC,B4GALT4,PKN1,MERTK,HDAC9,ZDHHC21,ADRBK1,IGF1R,CTSC,MGAT4A,ALG13,FUT8,TPST1,SGK3,UBE2J1,MAP3K9,SGK1,MAST4,SYK,PPP6R1,NUP85,CRTAP,NCOA2,GFPT1,RAB3B,TESK1,EIF5A2,MGAT4B,FURIN,COL7A1,EPHA1,YES1,PDK3,JADE2,CDK5R1,MAPKAPK2,GALNT3,FUCA1,NCOA3,UAP1,SERPINA1,FGFR2,SETD3,CSNK1G1,P4HA3,RYK,AGBL5,ZDHHC7,AURKA,STK39,CTSA,CFAP20,CEP41,JAK3,IFIH1,NUP58,HIPK3,MELK,EGLN1 |
| 6.450e-03 | -5.04 | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | 173 | 28 | 17758 | 1761 |
CD55,FBXL16,HSPG2,HOXB7,CRYM,BCL9,DNAJC3,PARP4,BTN3A2,KIF1C,BTN3A1,PSME1,RNF113A,MORF4L2,PRX,CHPF,PRDX4,SOCS3,DAPK2,SCARB2,COL13A1,ABHD12,OSBPL3,FAM114A1,PAPSS1,SGK3,NETO2,IRF7 |
| 6.490e-03 | -5.04 | TGACATY_UNKNOWN | MSigDB lists | TGACATY_UNKNOWN | 631 | 82 | 17758 | 1761 |
LTBP1,SLC2A4,SORBS1,TEX2,DDR1,CYP26A1,PDGFA,SS18,SESN3,ST5,MITF,DUSP10,PDE4D,MYT1,TRIM8,ACVR1C,SYNE2,SAT1,PRKAR2B,ATP1B1,SNX12,ABR,TRIM9,WIPI1,MAP2,KCNK1,MADD,INPP4B,SYT13,LEMD1,C1orf43,ARF6,ST3GAL1,LIFR,ARHGEF3,FRMD4A,IGFBP6,CHCHD7,DCAF7,PDIA3,COL4A5,TGFBR1,SBF1,TNFRSF19,FGF19,NRP2,SH2D4A,SLC9A2,FOXP2,CTSC,ANKS1B,SLC16A6,KIF13B,FLRT3,CALD1,CACNA1D,ERBB3,KLF9,IQGAP3,CITED2,ZRANB1,MYLIP,IGSF3,ARAP2,NR3C1,PIK3R1,LITAF,RUNX3,FOS,TP53INP2,BSDC1,XKRX,ARHGAP24,PLOD2,FGFR2,PELI2,SFMBT1,MDH1,GEM,HOOK1,JARID2,EHD1 |
| 6.520e-03 | -5.03 | GCCNNNWTAAR_UNKNOWN | MSigDB lists | GCCNNNWTAAR_UNKNOWN | 142 | 24 | 17758 | 1761 |
EPB41L5,IER5L,HPS3,GGA1,BCL9,ETV5,CBX6,NDRG2,TRIB2,PDGFB,SFXN5,CDKN2C,FOXP2,ITGA3,RALGPS2,BHLHE41,MITF,TOX2,ITPR1,CDKN1B,FAM117A,PITPNA,C1orf43,ABCA1 |
| 6.534e-03 | -5.03 | regulation of phosphoprotein phosphatase activity | biological process | GO:0043666 | 60 | 13 | 16441 | 1675 |
CALM2,PPP4R4,PPP1R2,PPP2R5A,NUAK1,CALM1,CALM3,CRY2,SLC39A10,PPP2R2D,PPP6R1,TIPRL,PPP2R3A |
| 6.535e-03 | -5.03 | CACCAGC,MIR-138 | MSigDB lists | CACCAGC,MIR-138 | 213 | 33 | 17758 | 1761 |
RMND5A,ARHGEF3,FRMD4A,CPEB4,CIT,RPS6KA1,CNOT8,EPHA4,ARL4C,MIER3,MGAT5B,SLC20A1,SPTB,VPS26A,RIMS3,OSBPL3,EPB41L4B,TIPARP,TRAM1,DVL2,SIRT1,THRB,PELI3,PDIK1L,TP53INP2,NFIX,C19orf66,LIMK1,AMMECR1,BMP1,NR4A3,KLF11,ZMIZ1 |
| 6.540e-03 | -5.03 | GSE3982_DC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_DC_VS_BASOPHIL_DN | 189 | 30 | 17758 | 1761 |
FBLN5,RHOA,REPS2,CNOT8,OSGIN2,NUCB2,SPTLC2,KBTBD11,IL18R1,SLC25A36,GALNT3,TTC21B,TMEM164,CARD8,PPP2R5A,ETS2,WIPI1,STK38,KBTBD2,OSBPL3,PASK,KLF3,PPM1H,EIF4EBP2,PDE4D,MYRIP,APOBEC3G,MPHOSPH9,CTDSP2,JARID2 |
| 6.540e-03 | -5.03 | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | 189 | 30 | 17758 | 1761 |
SORT1,ADCK3,BCL9,FTH1,CTSZ,TRIB2,MRPS36,SDC1,STK17B,ATP10D,SIRPA,XKRX,APOBEC3B,NCOA3,FRY,JAK1,METTL7A,STK38,ZFP36,BDH1,PLCG2,CST3,SGK3,SELK,PACSIN1,SLC25A30,C9orf72,TPCN1,RAB3IL1,TMEM131 |
| 6.540e-03 | -5.03 | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | 189 | 30 | 17758 | 1761 |
TIMP2,DEPDC1,DNAJC3,ABCG2,CDA,NUSAP1,GPSM2,DENND2D,CDK1,SLC25A4,PLOD2,TIMM8A,KCNN4,MITF,SECTM1,CD70,NFKBIZ,STK39,SERPINB6,PIM1,MINPP1,PDIA6,TRAF5,TRAM1,S100A13,HIPK3,GAB1,DVL2,CRTAP,KLF7 |
| 6.540e-03 | -5.03 | GSE10325_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_UP | 189 | 30 | 17758 | 1761 |
CPD,SLC39A8,S100A4,CORO2A,STAT4,ITGA6,PIK3R1,ARL4C,CYB561,PRKCQ,OPTN,PLCG1,ATP1A1,NGFRAP1,SEMA4D,MGAT4A,LRIG1,FAM102A,ARRB1,WWP1,PDE4D,PIM1,FHL1,RCAN3,MYBL1,TIAM1,TBC1D4,TOB1,RASGRP1,DOCK9 |
| 6.542e-03 | -5.03 | regulation of dendritic spine development | biological process | GO:0060998 | 47 | 11 | 16441 | 1675 |
GRN,FOXO6,PTEN,BHLHB9,PLK2,SIPA1L1,EPHA4,NRG1,ARF6,ITPKA,CDK5R1 |
| 6.553e-03 | -5.03 | LILRB1 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1) | protein interactions | 10859 | 8 | 4 | 16036 | 1726 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 6.553e-03 | -5.03 | Nedd4 (neural precursor cell expressed, developmentally down-regulated 4) | protein interactions | 17999 | 8 | 4 | 16036 | 1726 |
SCN5A,GUCD1,N4BP3,SCN3A |
| 6.553e-03 | -5.03 | ARMC9 (armadillo repeat containing 9) | protein interactions | 80210 | 8 | 4 | 16036 | 1726 |
DPP8,CTSC,PRPS2,CRTAP |
| 6.553e-03 | -5.03 | FXYD1 (FXYD domain containing ion transport regulator 1) | protein interactions | 5348 | 8 | 4 | 16036 | 1726 |
ATP1A1,ATP1B1,PRKACA,PTTG1 |
| 6.553e-03 | -5.03 | LILRB2 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2) | protein interactions | 10288 | 8 | 4 | 16036 | 1726 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 6.553e-03 | -5.03 | EMILIN3 (elastin microfibril interfacer 3) | protein interactions | 90187 | 8 | 4 | 16036 | 1726 |
ERLEC1,SCARA3,PLAUR,PASK |
| 6.564e-03 | -5.03 | MET (MET proto-oncogene, receptor tyrosine kinase) | protein interactions | 4233 | 57 | 13 | 16036 | 1726 |
CASP3,PLCG1,PTPRJ,CDH1,INPP5D,LRIG1,PIK3R1,CTTN,FBXO6,GAB1,RANBP9,SH3KBP1,FAS |
| 6.567e-03 | -5.03 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | 90 | 17 | 17775 | 1757 |
SGCE,LCA5,AKT1,NR3C1,TP53,ERBB2,IDH1,TXNDC11,PRX,SS18,DNAJC10,CDH1,PTEN,CDK19,PIK3CA,SORL1,TRAF5 |
| 6.576e-03 | -5.02 | positive regulation of stress-activated MAPK cascade | biological process | GO:0032874 | 131 | 23 | 16441 | 1675 |
MAP3K3,RIPK2,FZD4,EPHA4,PKN1,MAP3K6,FGF19,FZD7,CTGF,ANKRD6,NOD2,MAP3K9,DAB2IP,MDFIC,FZD5,MAP3K5,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI,XDH |
| 6.617e-03 | -5.02 | mitotic nuclear division | biological process | GO:0007067 | 353 | 51 | 16441 | 1675 |
SPC25,DLGAP5,KLHL13,CIT,ACTR8,EPS8,PTTG1,NDC80,CDCA8,KIF23,NUF2,CCNB1,CENPN,SAC3D1,WEE1,SETDB2,SNX18,PTEN,KIF14,NEK2,BUB1,PLK1,ZWINT,RHOA,PBK,ASPM,CDC20,MYBL2,CDCA2,NUSAP1,PKMYT1,CCNF,ANLN,KIF11,BORA,CDK1,FAM64A,CDCA5,FAM83D,TRIOBP,AURKA,CENPE,GEM,NDE1,RGS14,NCAPG2,UBE2C,CCNB2,REEP4,PPP2R2D,ESPL1 |
| 6.621e-03 | -5.02 | endoplasmic reticulum unfolded protein response | biological process | GO:0030968 | 109 | 20 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,DNAJC3,AMFR,ERO1A,PDIA5,DNAJB11,DNAJB9,LMNA,CCND1,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 6.621e-03 | -5.02 | negative regulation of cell morphogenesis involved in differentiation | biological process | GO:0010771 | 109 | 20 | 16441 | 1675 |
SEMA6B,RHOA,MFI2,CIT,RAPGEF2,LRP4,FBLN1,CDK5R1,AP1AR,SEMA4D,PTEN,VASN,CORO1C,DAB2IP,TACSTD2,SEMA3G,WNT3A,SEMA3A,TRIM62,SEMA3B |
| 6.654e-03 | -5.01 | - | gene3d domains | 2.30.40.10 | 8 | 4 | 9988 | 1080 |
DPYSL5,AMDHD1,DPYSL2,DPYSL3 |
| 6.663e-03 | -5.01 | LIMK1 (LIM domain kinase 1) | protein interactions | 3984 | 33 | 9 | 16036 | 1726 |
MAPKAPK2,SSH3,MBP,CDKN1C,SSH1,LIMK1,ARRB1,NRG1,ABCA1 |
| 6.687e-03 | -5.01 | COL6A1 (collagen, type VI, alpha 1) | protein interactions | 1291 | 17 | 6 | 16036 | 1726 |
PDIA3,PDGFA,DNAJB11,FBXO6,PDGFB,LGALS3BP |
| 6.687e-03 | -5.01 | ADRA1D (adrenoceptor alpha 1D) | protein interactions | 146 | 17 | 6 | 16036 | 1726 |
SNTA1,SNTB1,AMFR,SNTB2,CKAP4,UTRN |
| 6.687e-03 | -5.01 | KCNJ12 (potassium channel, inwardly rectifying subfamily J, member 12) | protein interactions | 3768 | 17 | 6 | 16036 | 1726 |
SNTA1,DLG3,SNTB1,PRKACA,SNTB2,DLG1 |
| 6.687e-03 | -5.01 | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | MSigDB lists | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | 127 | 22 | 17758 | 1761 |
FAM169A,SAT1,FBXO2,CDA,HTATIP2,IL18,GDF15,ISYNA1,S100A2,DNAJB9,FUCA1,FAAH,FGD6,CD70,SERPINI1,IRF7,TACSTD2,LGMN,TSPAN1,F2RL1,TOB1,NXT2 |
| 6.687e-03 | -5.01 | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | MSigDB lists | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | 127 | 22 | 17758 | 1761 |
CPD,LASP1,FBLN5,NUAK1,NR3C1,LITAF,ETS1,COL12A1,TMCC3,NFIX,OTUD1,SMTNL2,BMP7,SIPA1L1,MATN2,LRIG1,FAM110C,PRKCDBP,LRRK1,PKIA,RGMA,FGD1 |
| 6.739e-03 | -5.00 | PID_IL2_1PATHWAY | MSigDB lists | PID_IL2_1PATHWAY | 55 | 12 | 17758 | 1761 |
MAPKAPK2,IRS2,RHOA,JAK1,PIK3R1,PIK3CA,MAPK11,FOS,JAK3,SYK,RASA1,SOCS3 |
| 6.739e-03 | -5.00 | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | MSigDB lists | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | 55 | 12 | 17758 | 1761 |
CCND1,TIMP3,ITGA3,ITGB8,PLAUR,MICB,P4HA2,AXL,BMP1,S100A2,F2RL1,CRISPLD2 |
| 6.744e-03 | -5.00 | ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) | protein interactions | 471 | 70 | 15 | 16036 | 1726 |
PGM1,SHMT1,TXN,JAK1,STK26,DNM1L,PAPSS1,AHCY,GLO1,PLIN3,SPR,HSPB1,ISOC1,CTH,ELF3 |
| 6.759e-03 | -5.00 | laminin binding | molecular function | GO:0043236 | 29 | 8 | 16491 | 1673 |
BCAM,ITGA3,LGALS3,LYPD3,ITGA7,NTN4,TINAGL1,DAG1 |
| 6.761e-03 | -5.00 | - | gene3d domains | 3.30.50.10 | 57 | 13 | 9988 | 1080 |
THRB,NR3C1,GATA2,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 6.768e-03 | -5.00 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 457 | 62 | 17758 | 1761 |
GAA,ENO2,ALDH6A1,TBC1D1,HLA-E,DCAF7,TP53,PKP2,CALM3,PKN1,NUCB2,PJA2,TIPRL,TNFSF9,AIP,GNS,CALM2,ADRBK1,CDK16,RIMS3,DLG1,FXYD5,SLC44A2,SORL1,FAM102A,CD70,CNOT6L,MYLIP,GM2A,KDELR1,CTH,SUSD3,PCGF5,LOC81691,MBP,CD55,ZC3H11A,SEPT6,AMFR,CALM1,SAT1,MGAT4B,PPARA,NFE2L1,HMG20B,RUNX3,NPC2,TYSND1,LEPR,ADRBK2,CD83,NCOA3,MID1IP1,TRIM69,NFKBIA,CAB39,UACA,DHTKD1,HMGA1,TMEM120A,TMEM159,GLCCI1 |
| 6.771e-03 | -5.00 | V$NRF2_Q4 | MSigDB lists | V$NRF2_Q4 | 246 | 37 | 17758 | 1761 |
GAS2L1,UNKL,PPP4R4,TNRC6C,LRRFIP2,FRMD4A,HSPG2,NUAK1,BLVRB,ETV5,NDRG2,RAB6A,SRPX2,BEX2,VPS26A,TFAP4,PSMD1,SLC16A6,LMO4,ABCA2,ADAM15,ABCD1,MYH14,PDE4D,MDFI,TGIF1,CAPN6,TMEM151A,ATP1B1,SFXN5,PRX,TMEM54,LIMK1,CAB39,SH3BGRL2,DRP2,RARG |
| 6.778e-03 | -4.99 | HILLION_HMGA1B_TARGETS | MSigDB lists | HILLION_HMGA1B_TARGETS | 90 | 17 | 17758 | 1761 |
PCOLCE,TIMP2,PSMB4,PLAUR,ERBB2,SLC25A5,FOS,GRM5,PDGFA,RPL12,ATP5H,LIMK1,NFKBIA,ARF6,UNC5B,ALDH3A2,GPX4 |
| 6.780e-03 | -4.99 | Rho_GTPase_activation_prot | interpro domains | IPR008936 | 90 | 17 | 18293 | 1814 |
ARHGAP11A,ARAP3,ARAP2,DEPDC1,IQGAP1,RALBP1,RASA2,PIK3R1,PLXNA1,ABR,RASA1,ARHGAP35,ARHGAP24,SH3BP1,FAM13B,DAB2IP,IQGAP3 |
| 6.782e-03 | -4.99 | MODULE_255 | MSigDB lists | MODULE_255 | 414 | 57 | 17758 | 1761 |
LMTK3,FAM169A,CDH22,AASS,MRPS15,TP53,SLC25A27,C6orf106,CTSZ,ISYNA1,NANS,IL18R1,CMTM6,C9orf69,CYP1A1,RNF220,CDK16,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,CNOT6L,FAIM,FAR2,CITED2,ATG4D,AMOTL2,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,PTPRF,AMZ2,FUCA1,NEIL1,TIMP3,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,PKIA,RRAGD |
| 6.789e-03 | -4.99 | multicellular organismal metabolic process | biological process | GO:0044236 | 102 | 19 | 16441 | 1675 |
COL9A3,ADAMTS2,MRC2,COL6A2,P3H2,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,TIPARP,COL16A1 |
| 6.801e-03 | -4.99 | human chr1q32 | chromosome location | human chr1q32 | 40 | 8 | 26250 | 1887 |
MAPKAPK2,CD55,LPGAT1,CR2,PIK3C2B,TRAF5,RNPEP,SOX13 |
| 6.810e-03 | -4.99 | CSR_LATE_UP.V1_UP | MSigDB lists | CSR_LATE_UP.V1_UP | 158 | 26 | 17758 | 1761 |
ZWINT,FOXM1,CKAP2,PBK,DRAP1,ITGA6,MYBL2,CDCA8,CCDC34,DNAJB11,NUF2,MRAS,ANLN,CDK1,CRISPLD2,PRIM1,TIMP3,ZNF367,NETO2,FAM83D,TUBG1,TSPAN13,LTBP2,UBE2C,SLC16A5,DCBLD1 |
| 6.816e-03 | -4.99 | TTANTCA_UNKNOWN | MSigDB lists | TTANTCA_UNKNOWN | 892 | 111 | 17758 | 1761 |
LTBP1,TXN,PPM1J,SLC25A13,CAMKK1,FHDC1,IL13RA1,CA8,SPTB,DENND2D,SYTL2,PLS3,CDKN2C,NOV,ST5,RNF220,WDR44,LMO4,ALDH1A3,SLC44A1,MITF,FABP6,ATRNL1,RTKN2,TINAGL1,ACSL4,PDE4D,SCN2A,LMAN1,SULF2,SMARCA2,C6orf1,SNTB2,SERTAD4,SAT1,ERBB2IP,ROR1,ATP10D,NFIX,TAPBP,MAP2,PTK7,LIMK1,HOXA9,CORO1C,KLF5,EFNA5,PRIMA1,ARF6,LIFR,NR3C2,MAFF,CPEB4,IGFBP6,LRRFIP2,KLHL13,RASA2,HAL,SDC4,FAM134A,COL4A5,ETS1,VPS26A,NRP2,DNAJB9,PDIA4,NEO1,FOXP2,CTNNBIP1,AIM1L,IGF1R,CYR61,LYPD3,FLRT3,FAM13B,RRBP1,TAGLN2,PIM1,ZRANB1,CITED2,GAD1,PLCB2,RBMS2,TRAK2,HMMR,TGIF1,ARAP2,ELK3,BCL9,PRICKLE1,STRADB,TCF7,RUNX3,PRDX4,BCAR3,MAPKAPK2,ARHGAP24,PITX2,AP1AR,ETS2,MFSD2A,SH3BGRL2,LTBP2,HMGA1,MAL2,MAP3K5,ZMIZ1,SEMA3A,L1CAM,PKIA,DIS3L |
| 6.831e-03 | -4.99 | JAEGER_METASTASIS_UP | MSigDB lists | JAEGER_METASTASIS_UP | 42 | 10 | 17758 | 1761 |
ENPP1,PAPSS2,PLOD2,TBC1D1,EPS8,AURKA,NCAM1,H2AFV,MERTK,CKS2 |
| 6.831e-03 | -4.99 | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | MSigDB lists | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | 42 | 10 | 17758 | 1761 |
IRS2,ATP1A1,SCNN1A,PIK3R1,PIK3CA,SGK1,ATP1B1,ATP1B3,PIK3CD,NR3C2 |
| 6.831e-03 | -4.99 | REACTOME_PLC_BETA_MEDIATED_EVENTS | MSigDB lists | REACTOME_PLC_BETA_MEDIATED_EVENTS | 42 | 10 | 17758 | 1761 |
PLA2G4A,CALM2,ADRBK1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PLCB2,PRKACA |
| 6.839e-03 | -4.99 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | 76 | 15 | 17775 | 1757 |
GNAS,CDH1,AKT1,PTEN,ATP9A,CASP9,SLC2A6,PIK3CA,TP53,ABCA2,NUCB2,IDH1,BCAR1,GNA11,LZTS1 |
| 6.846e-03 | -4.98 | Rac guanyl-nucleotide exchange factor activity | molecular function | GO:0030676 | 13 | 5 | 16491 | 1673 |
TIAM1,EPS8L2,FARP2,ARHGEF4,SPATA13 |
| 6.846e-03 | -4.98 | misfolded protein binding | molecular function | GO:0051787 | 13 | 5 | 16491 | 1673 |
DNAJC10,F12,HDAC6,DNAJC3,DNAJB9 |
| 6.846e-03 | -4.98 | peptidyl-proline dioxygenase activity | molecular function | GO:0031543 | 13 | 5 | 16491 | 1673 |
EGLN3,P3H2,P4HA2,P4HA3,EGLN1 |
| 6.846e-03 | -4.98 | metalloaminopeptidase activity | molecular function | GO:0070006 | 13 | 5 | 16491 | 1673 |
ERAP1,LTA4H,RNPEP,ERAP2,METAP2 |
| 6.850e-03 | -4.98 | aldehyde dehydrogenase (NAD) activity | molecular function | GO:0004029 | 18 | 6 | 16491 | 1673 |
ALDH7A1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 6.867e-03 | -4.98 | Signaling by Rho GTPases | REACTOME pathways | R-HSA-194315 | 399 | 58 | 8202 | 867 |
MYL9,ARHGAP11A,WASF3,ARHGEF3,ARAP3,SPC25,NF2,ARHGEF11,TRIP10,CIT,CENPI,RALBP1,IQGAP1,NDC80,CDCA8,CALM3,NUF2,NCKAP1,PKN1,CENPN,ARHGEF16,CALM2,KIF5B,CDH1,KIF14,FAM13B,KLC3,CDKN1B,BUB1,CTTN,MYH14,IQGAP3,TIAM1,NUP85,NCOA2,DVL2,PLK1,ARAP2,ZWINT,RHOA,CENPA,CALM1,CDC20,DIAPH2,ARHGDIB,ABR,ARHGAP35,ARHGAP24,PPP2R5A,LIMK1,RHOBTB2,CENPE,ARPC2,NDE1,ARHGEF9,MYL12B,ARHGEF4,FGD1 |
| 6.868e-03 | -4.98 | MODULE_88 | MSigDB lists | MODULE_88 | 811 | 102 | 17758 | 1761 |
MYL9,BCAM,NQO1,HSPG2,EPAS1,S100A11,CRYM,THRA,PTTG1,NRG2,COL18A1,SDC1,PHLDA1,IER3,CCND1,EPCAM,SCNN1A,CDH1,ALDH1A3,CLDN4,TACSTD2,GOT1,IFIT1,ACOX2,LGMN,TSPAN1,SMAGP,CKS2,SGCE,COL6A2,S100A4,CDC20,F12,CCNF,MDK,ENPP1,GPRC5B,BMP1,NRGN,ABCA1,GRN,PRSS8,PCOLCE,IGFBP6,ATP9A,ITGA6,DNAJB2,BLVRB,SOX9,GNE,GDF15,SEPP1,DHRS3,DNAH3,HOXB2,TSPAN7,CA2,ITGA3,CYR61,CTSC,LYPD3,GATA2,KCNN4,BDH1,TBCD,COL6A1,GALNS,TFAP2A,ALDH7A1,IGFBP2,ERBB3,CITED2,PLCB2,ALDH3A2,RIMS2,FADS2,SHMT1,NR4A1,FURIN,AK4,TCF7,COL7A1,FOS,CDK5R1,CYB5A,TIMP3,SERPINA1,SLC4A4,ETS2,PVRL2,FGFR2,DHRS2,ITGA7,DTX4,CDK18,STK39,JAK3,UBE2C,L1CAM,OCLN,XDH,CD33 |
| 6.882e-03 | -4.98 | response to decreased oxygen levels | biological process | GO:0036293 | 272 | 41 | 16441 | 1675 |
CASP3,PINK1,NKX3-1,SLC2A4,CPEB4,EPAS1,TP53,ITPR2,CCNB1,PDGFB,ETS1,LMNA,CYP1A1,ADORA1,CTGF,PTEN,BMP7,VASN,CST3,CDKN1B,AHCY,TWIST1,CITED2,EGLN3,SIRT1,RHOA,AKT1,RGCC,PPARA,PRKCQ,SLC11A2,LOXL2,PDK3,ATP1B1,EDNRA,SOCS3,PLOD2,ITPR1,NR4A2,CPEB2,EGLN1 |
| 6.900e-03 | -4.98 | PI3K/AKT Signaling in Cancer | REACTOME pathways | R-HSA-2219528 | 85 | 17 | 8202 | 867 |
AKT1,NR4A1,CASP9,PIK3R1,NRG2,ERBB2,PDGFB,FGF19,IRS2,PDGFA,FGFR2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 6.902e-03 | -4.98 | negative regulation of cell-cell adhesion | biological process | GO:0022408 | 139 | 24 | 16441 | 1675 |
EPB41L5,CASP3,NF2,SERPINE2,LGALS3,ITCH,UBASH3B,PPARA,RGCC,PDE5A,ERBB2,CD274,EPCAM,SWAP70,CDH1,SPINT2,BCL6,PRKG1,DLG1,FXYD5,C10orf54,NDFIP1,JAK3,SOCS5 |
| 6.902e-03 | -4.98 | sphingolipid metabolic process | biological process | GO:0006665 | 139 | 24 | 16441 | 1675 |
UGT8,HEXB,ASAH1,TEX2,ARSK,SPTLC2,CPTP,SGPL1,B4GALNT1,ALDH3B1,ALDH5A1,ITGB8,ARSG,A4GALT,PLPP3,BAX,SERINC2,CTSA,GLA,ARSB,ST3GAL1,ALDH3A2,NAGA,GM2A |
| 6.913e-03 | -4.97 | V$IRF_Q6 | MSigDB lists | V$IRF_Q6 | 230 | 35 | 17758 | 1761 |
PARP12,CPEB4,KLHL13,ZCCHC24,HLA-F,ETV5,SELL,PRKACA,AKIRIN1,CCND1,DTX3L,FUT8,RRBP1,DUSP10,ADAM15,TRIM21,IRF2,CDH3,TWIST1,HLA-C,ARMCX6,RBMS2,PCGF5,KCNIP3,NUB1,SAT1,SYNE2,SLC11A2,PITX2,TAPBP,PLEKHH2,NOD2,SEMA3A,RARG,EHD1 |
| 6.920e-03 | -4.97 | embryonic skeletal system morphogenesis | biological process | GO:0048704 | 95 | 18 | 16441 | 1675 |
SPEF2,RUNX2,GRHL2,HSPG2,HOXB7,TGFBR1,OSR2,HOXB2,SIX4,GNAS,FGFR2,MEGF8,BMP7,TFAP2A,DLG1,TWIST1,OSR1,MDFI |
| 6.920e-03 | -4.97 | regulation of cytokinesis | biological process | GO:0032465 | 95 | 18 | 16441 | 1675 |
RHOA,AKT1,CIT,CALM1,RGCC,CALM3,KIF23,PSMD10,PDGFB,STIL,CCND1,CALM2,E2F7,IGF1R,KIF14,AURKA,PIM1,E2F8 |
| 6.924e-03 | -4.97 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | 135 | 23 | 17758 | 1761 |
ARAP3,KIF20A,DLGAP5,HJURP,ASPM,PTTG1,NUSAP1,CCNB1,BARD1,SH3KBP1,TOP2A,RAB15,FAM64A,UAP1,IMPAD1,AURKA,BUB1,CENPE,IQGAP3,UBE2C,CCNB2,FAM69A,CKS2 |
| 6.933e-03 | -4.97 | negative regulation of cell-matrix adhesion | biological process | GO:0001953 | 29 | 8 | 16441 | 1675 |
NF2,ACVRL1,PTEN,CORO1C,PIK3R1,BCL6,ADAM15,RASA1 |
| 6.933e-03 | -4.97 | salivary gland morphogenesis | biological process | GO:0007435 | 29 | 8 | 16441 | 1675 |
NKX3-1,TWSG1,FGFR2,BMP7,PLXNA1,SEMA3A,DAG1,NFIB |
| 6.940e-03 | -4.97 | SUSD4 (sushi domain containing 4) | protein interactions | 55061 | 39 | 10 | 16036 | 1726 |
MAN2A2,ADAMTS2,HAPLN3,ITGA7,FRAS1,PLXNA1,ITGAV,ARSB,ARSK,TXNDC11 |
| 6.961e-03 | -4.97 | breast-hyperplasia-atypical_ductal_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_ductal_hyperplasia | 24 | 7 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53 |
| 6.961e-03 | -4.97 | atypical_ductal_hyperplasia | COSMIC cancer mutations | atypical_ductal_hyperplasia | 24 | 7 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53 |
| 6.969e-03 | -4.97 | NUCLEOTIDE_BINDING | MSigDB lists | NUCLEOTIDE_BINDING | 222 | 34 | 17758 | 1761 |
PINK1,PEX6,TP53,ABCG2,TGFBR1,TRIB2,AIFM2,DHRS3,ABCD4,DAPK2,DAPK1,ABCA2,PIM1,ABCC1,SEPHS1,MX1,GCLC,SEPT6,PIF1,NUBP1,STK17B,MAP3K6,RHEB,DGKE,STK17A,ACVRL1,RND3,ATP7B,STK38,ABCB1,GEM,ARF6,MAP3K5,ABCG1 |
| 6.969e-03 | -4.97 | HSPA4 (heat shock 70kDa protein 4) | protein interactions | 3308 | 312 | 48 | 16036 | 1726 |
PINK1,NQO1,NF2,EPAS1,THRA,DNAJB2,DNAJC3,ASB9,TP53,DNAJB11,PSMD10,ERBB2,TGFBR1,MORF4L2,HDAC6,PHLDA1,DENND2D,APPBP2,TEAD3,ZFP36,BAX,TUBG1,SGK1,TAGLN2,PIM1,APOBEC3G,PPP6R1,SIRT1,MAP3K3,PLK1,THRB,SEC23A,HES1,AKT1,PRSS23,AMFR,CALM1,NUB1,EZR,CD40,CDK1,DNAJC10,LIMK1,FAM114A1,HDAC1,MAP3K5,HSPB1,NR3C2 |
| 6.970e-03 | -4.97 | PHONG_TNF_TARGETS_UP | MSigDB lists | PHONG_TNF_TARGETS_UP | 62 | 13 | 17758 | 1761 |
BTG3,NKX3-1,ETS2,PLK2,ZFP36,FJX1,NFKBIA,SDC4,DUSP10,GEM,FOS,CD83,IER3 |
| 6.970e-03 | -4.97 | V$AHR_01 | MSigDB lists | V$AHR_01 | 62 | 13 | 17758 | 1761 |
CCND1,CYP1A1,NR3C1,H1F0,DPYSL2,LMO4,ITPR1,TP53,HMG20B,RUNX3,MORF4L2,NCAM1,PRX |
| 6.971e-03 | -4.97 | trophoblast giant cell differentiation | biological process | GO:0060707 | 13 | 5 | 16441 | 1675 |
E2F7,E2F8,SOCS3,MDFI,PLK4 |
| 6.971e-03 | -4.97 | negative regulation of macrophage derived foam cell differentiation | biological process | GO:0010745 | 13 | 5 | 16441 | 1675 |
ITGAV,ABCA1,NFKBIA,ABCG1,PPARA |
| 6.971e-03 | -4.97 | phospholipid scrambling | biological process | GO:0017121 | 13 | 5 | 16441 | 1675 |
ANO9,PLSCR1,ANO4,ANO6,XKR8 |
| 6.971e-03 | -4.97 | regulation of cell communication by electrical coupling | biological process | GO:0010649 | 13 | 5 | 16441 | 1675 |
CALM3,CALM2,PDE4D,CABP1,CALM1 |
| 6.971e-03 | -4.97 | response to water | biological process | GO:0009415 | 13 | 5 | 16441 | 1675 |
AKR1B1,COL18A1,LRP11,TFAP2A,CD9 |
| 6.971e-03 | -4.97 | negative regulation of peptidyl-threonine phosphorylation | biological process | GO:0010801 | 13 | 5 | 16441 | 1675 |
CALM3,CALM2,SPRED1,SPRY2,CALM1 |
| 6.985e-03 | -4.96 | homeostasis of number of cells | biological process | GO:0048872 | 185 | 30 | 16441 | 1675 |
EMX1,CASP3,ADD1,LGR4,AKT1,EPAS1,THRA,SOX9,RC3H2,NFE2L1,SLC11A2,PKN1,FAS,MECOM,FECH,NOV,GATA2,SIVA1,AXL,CSF1,BCL6,BAX,PTBP3,PPP2R3C,PIK3CD,ZBTB18,F2R,JAK3,CCNB2,SLC25A38 |
| 6.994e-03 | -4.96 | filopodium assembly | biological process | GO:0046847 | 18 | 6 | 16441 | 1675 |
FGD6,EZR,ITGA6,ARHGEF4,SPATA13,FGD1 |
| 6.994e-03 | -4.96 | protein hydroxylation | biological process | GO:0018126 | 18 | 6 | 16441 | 1675 |
EGLN3,P4HA2,P3H2,P4HA3,CRTAP,EGLN1 |
| 6.994e-03 | -4.96 | microvillus assembly | biological process | GO:0030033 | 18 | 6 | 16441 | 1675 |
FXYD5,EZR,KLF5,STK26,RAPGEF2,RAP2C |
| 6.994e-03 | -4.96 | positive regulation of alpha-beta T cell proliferation | biological process | GO:0046641 | 18 | 6 | 16441 | 1675 |
IL18,CD55,RIPK2,SYK,HLA-E,HLA-A |
| 7.004e-03 | -4.96 | ureteric bud development | biological process | GO:0001657 | 88 | 17 | 16441 | 1675 |
HES1,FMN1,RET,SOX9,SDC4,SDC1,EPCAM,CTNNBIP1,FAT4,FGFR2,NPNT,BMP7,DLG1,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 7.004e-03 | -4.96 | Peptidase_C1 | pfam domains | PF00112 | 13 | 5 | 16629 | 1696 |
CTSL,CTSZ,TINAGL1,CTSC,CTSV |
| 7.012e-03 | -4.96 | AAGCAAT,MIR-137 | MSigDB lists | AAGCAAT,MIR-137 | 214 | 33 | 17758 | 1761 |
RUNX2,EPHA4,CTDSPL,MORC4,MGAT5B,RAVER2,SGPL1,RCN1,RNF128,FLRT3,RIMS3,MITF,ANKRD12,LIMCH1,CTDSP2,OXR1,FURIN,ATP1B1,FNDC3A,SLC25A5,PTGFRN,C3orf58,MUM1L1,MAPKAPK2,HLF,SLC6A6,KLF12,PDLIM3,PHLPP2,RAP2C,YOD1,SHROOM2,NR3C2 |
| 7.017e-03 | -4.96 | AMPK signaling pathway | KEGG pathways | hsa04152 | 123 | 23 | 6908 | 758 |
SIRT1,PRKAA2,ACACB,SLC2A4,AKT1,TBC1D1,CAMKK1,PIK3R1,STRADB,LEPR,PPP2R3A,RHEB,CCND1,IRS2,PRKAG2,PPP2R5A,IGF1R,PIK3CA,CAB39,ADIPOR1,PPP2R3C,PIK3CD,PPP2R2D |
| 7.017e-03 | -4.96 | AMPK signaling pathway | KEGG pathways | ko04152 | 123 | 23 | 6908 | 758 |
SIRT1,PRKAA2,ACACB,SLC2A4,AKT1,TBC1D1,CAMKK1,PIK3R1,STRADB,LEPR,PPP2R3A,RHEB,CCND1,IRS2,PRKAG2,PPP2R5A,IGF1R,PIK3CA,CAB39,ADIPOR1,PPP2R3C,PIK3CD,PPP2R2D |
| 7.026e-03 | -4.96 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | 182 | 29 | 17758 | 1761 |
TIMP2,PINK1,SPC25,KIF20A,IL15RA,CDKN1C,ZCCHC24,CBX6,PDE5A,NENF,PKMYT1,CCNF,GSTP1,CDK1,HPCAL4,OPTN,IER3,RCN1,MMP15,AXL,RRBP1,GOT1,MANF,LMAN1,CCNB2,UBE2C,GAB1,FAH,ARHGEF4 |
| 7.026e-03 | -4.96 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | 182 | 29 | 17758 | 1761 |
RMND5A,SSH3,LZTFL1,ARMCX3,CELSR2,TMEM55B,EFHD2,KLK6,KCTD2,TNFSF9,KREMEN1,RASA1,TMCC3,KIF5B,ETS2,KIAA1107,DCK,RAP2C,DAPK1,STEAP2,TNFRSF12A,ALDH7A1,C8orf58,DLG3,GLCCI1,TIAM1,CXorf56,RGMA,ATG4D |
| 7.026e-03 | -4.96 | GSE3982_EOSINOPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_DN | 182 | 29 | 17758 | 1761 |
CD99,SIGIRR,GCLM,DLGAP5,COG2,CAST,PCBP3,STAT4,SEPT6,C6orf106,PSME1,IL27RA,RAD17,LDB2,LTBP3,ABCD4,AMZ2,ENDOD1,RNF220,JAK1,XYLT2,OSBPL3,ARRB1,MDH1,PIK3C2B,MANF,MINPP1,NCAM1,RUSC1 |
| 7.026e-03 | -4.96 | GSE3982_EOSINOPHIL_VS_MAC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_UP | 182 | 29 | 17758 | 1761 |
DLGAP1,PLA2G4A,ACACB,GOLIM4,REPS2,NLRX1,TACC1,SYNE2,FOS,KBTBD11,ARHGEF40,HPCAL4,PRRG4,CDK5R1,ADD3,JAK1,WIPI1,FAM13B,KLF3,SLC44A1,PRDM5,PNPLA6,ZDHHC7,NR4A2,GAD1,MYT1,GAB1,CTDSP2,JARID2 |
| 7.041e-03 | -4.96 | MODULE_297 | MSigDB lists | MODULE_297 | 76 | 15 | 17758 | 1761 |
KLK10,KLK5,LMTK3,CA2,KLHL13,FXYD3,ITGA6,ALDH1A3,CDH3,COL7A1,PPP1R14C,F2RL1,S100A2,EFNB1,CYP26A1 |
| 7.050e-03 | -4.95 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | 190 | 30 | 17758 | 1761 |
GCA,EPAS1,SLC25A13,PTTG1,EFHD2,BCL2L1,BMP2K,CMTM7,IER3,CD109,SS18,SLCO4A1,PPP2R5A,UEVLD,WIPI1,KCNN4,IMPAD1,DBI,NOD2,NR4A3,ITGAV,PDE4D,GEM,ZMIZ1,BTBD3,SYTL3,CPPED1,GM2A,FAH,C9orf9 |
| 7.050e-03 | -4.95 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | 190 | 30 | 17758 | 1761 |
LTBP1,NFKBIE,ADD1,ZCCHC24,ACO1,GLO1,HOXB2,PSMA4,H1FX,GLCE,PDIA4,CDS1,SLC25A36,BTG3,CARD8,KIAA1107,SCG2,KIF14,FAM20B,KIAA0319,TUBG1,OSTF1,STK39,ATP1B3,ACSL4,CACNA1D,ARL4D,PLOD3,SHROOM2,CTH |
| 7.050e-03 | -4.95 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_DN | 190 | 30 | 17758 | 1761 |
CPD,LZTFL1,IL15RA,RIPK2,RASA2,NUB1,GABRG2,MRAS,SPTLC2,MAP3K6,LEPR,CASP4,CYP39A1,PSMA4,REPS1,RAD23A,RNF128,ADRBK1,PVRL2,HOXA9,NFKBIA,MITF,TWIST1,TAGLN2,CTTN,CITED2,TIPARP,MAFF,C9orf72,AHR |
| 7.050e-03 | -4.95 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | 190 | 30 | 17758 | 1761 |
SUN2,ANXA3,TGIF1,MMD,TTC39B,HOXB7,UBASH3B,PIK3R1,DIAPH2,RUNX3,ADCK5,ATP1B1,CD40,DHRS3,IL18R1,TTYH3,KLHL2,CDH1,PVRL2,CTSC,RAB11FIP2,RINL,LRIG1,TFAP2A,SGK1,NTN4,PACSIN1,F2RL1,MYL12B,SULF2 |
| 7.050e-03 | -4.95 | GSE360_DC_VS_MAC_T_GONDII_UP | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_UP | 190 | 30 | 17758 | 1761 |
COL9A3,PCOLCE,TXN,PSME2,HMGN3,BCL2L1,TIPRL,PPP2R3A,NRP2,PARM1,CD83,B4GALNT1,TIMP3,CTGF,CTSC,DHRS2,WFS1,NMI,MATN2,SPINT2,NR4A3,ARVCF,TACSTD2,OSTF1,ARSB,TRAF5,ACOT7,FAM69A,IGSF3,LAMP3 |
| 7.050e-03 | -4.95 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 190 | 30 | 17758 | 1761 |
HMMR,ANXA3,PRODH,CENPA,SPC25,DLGAP5,PBK,SEPT6,C3orf52,SDC4,PTTG1,MORC4,GLO1,IL18R1,WEE1,DOLPP1,NFKBIA,PASK,SECTM1,ABCA2,FAM117A,AURKA,TWIST1,YOD1,BUB1,PDE4D,PIK3CD,DLG3,CCNB2,APOBEC3G |
| 7.050e-03 | -4.95 | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | 190 | 30 | 17758 | 1761 |
CCNE2,TGIF1,SLC25A24,MRPL44,ASPM,MPP1,IQGAP1,ARMC7,TCF7,SLC36A4,STIL,GALNT3,PPP2R5A,DPYSL2,DCK,RPL39,CDCA5,AIM1,NLRC5,PIK3CA,ECI2,DUSP10,NR4A2,TSPAN13,ATP1B3,F2R,ARSB,MED30,SULF2,TMEM131 |
| 7.050e-03 | -4.95 | GSE13306_RA_VS_UNTREATED_TCONV_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_DN | 190 | 30 | 17758 | 1761 |
ZNF462,PARP12,CRB3,IFITM3,CHCHD7,FZD4,DAP,LITAF,MTRF1L,CYB561,SLC11A2,FTH1,RAB38,IL18R1,ADD3,ALDH5A1,NGFRAP1,DCK,GTF2F2,TFAP2A,KCNS3,BMP1,CDH3,WWP1,MDH1,OAS3,SEMA3G,F2RL1,SLC16A5,EHD1 |
| 7.050e-03 | -4.95 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | 190 | 30 | 17758 | 1761 |
SMARCA2,SLC25A24,TNRC6C,LGALS3,PLSCR1,STAU2,PANK1,EFHD2,TCF7,CAMK1D,DHRS3,DENND2D,CDK5R1,GPLD1,RASSF8,RNF220,GNPTAB,RGS3,LRIG1,TOX2,BCL6,CD9,PGM2L1,FAM102A,SERPINB6,STK39,TSPAN13,PPP2R2D,NRBP1,GCNT1 |
| 7.055e-03 | -4.95 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | 198 | 31 | 17758 | 1761 |
GAS2L1,SYPL1,PGM1,ALDH2,ENO2,SNTB2,CALM1,ARL4C,CALM3,GTF3A,CRABP2,FOS,REPS1,DCP2,LMNA,CALM2,ADD3,RPS6KA2,PTEN,SEMA4D,PLOD2,LMO4,SORL1,ECE1,LGMN,LTA4H,USF2,CTDSP2,CRTAP,ABCG1,CD33 |
| 7.055e-03 | -4.95 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 198 | 31 | 17758 | 1761 |
RMND5A,MX1,ARAP3,USP18,EPS8,CTDSPL,HERC5,GDF15,TEX2,SEPP1,SLC20A1,PHLDA1,DDR1,C11orf95,TP53I3,DAG1,PLS3,PDGFA,APLP2,SLCO4A1,CYP1A1,KCNN4,CSF1,SIVA1,FJX1,UBE2J1,ECI2,IFIT1,ATP1B3,HSPB1,L1CAM |
| 7.058e-03 | -4.95 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 120 | 21 | 17758 | 1761 |
DOCK4,ANXA3,FRMD4A,GGA1,PYROXD2,ATP8A1,CORO2A,SLC11A2,TNS1,TGFBR1,SEPP1,SFXN5,CYP4F3,NRP2,PARM1,CPNE2,RPS6KA2,BHLHE41,TACSTD2,TMEM37,ALPK1 |
| 7.060e-03 | -4.95 | LIN_MELANOMA_COPY_NUMBER_UP | MSigDB lists | LIN_MELANOMA_COPY_NUMBER_UP | 69 | 14 | 17758 | 1761 |
CCND1,PSMB4,SALL4,DNM1L,ATP9A,IQGAP1,MITF,FAM63A,ECI2,RFX5,CEP41,ANO1,NAGA,FGF19 |
| 7.061e-03 | -4.95 | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 36 | 9 | 17775 | 1757 |
KIF5B,SS18,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1 |
| 7.084e-03 | -4.95 | MURATA_VIRULENCE_OF_H_PILORI | MSigDB lists | MURATA_VIRULENCE_OF_H_PILORI | 24 | 7 | 17758 | 1761 |
CTTN,COL6A2,L1CAM,TMPRSS4,SOX9,COL6A1,BCL6 |
| 7.084e-03 | -4.95 | VALK_AML_CLUSTER_8 | MSigDB lists | VALK_AML_CLUSTER_8 | 24 | 7 | 17758 | 1761 |
FECH,TNS1,BCAM,CDH1,OPTN,ABCG2,TRAK2 |
| 7.084e-03 | -4.95 | TOMIDA_METASTASIS_UP | MSigDB lists | TOMIDA_METASTASIS_UP | 24 | 7 | 17758 | 1761 |
GNAS,DNER,PTTG1,CKAP4,TFAP2A,IER3,METAP2 |
| 7.084e-03 | -4.95 | NOJIMA_SFRP2_TARGETS_DN | MSigDB lists | NOJIMA_SFRP2_TARGETS_DN | 24 | 7 | 17758 | 1761 |
GAS2L1,GRN,MX1,CCND1,TACSTD2,BCL2L1,SGPL1 |
| 7.127e-03 | -4.94 | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | 255 | 38 | 17758 | 1761 |
GRN,GAA,TRIM2,SERPINE2,S100A11,TBC1D1,DNAJB2,NCKAP1,H1FX,IL17RB,B3GALNT1,IGF1R,ADRBK1,DPYSL2,RRBP1,CD9,RCAN3,EGLN3,ARL4D,MAST4,S100A13,GM2A,IGSF3,MX1,MGAT4B,SERTAD3,CR2,YES1,ABR,FRMD4B,MAPKAPK2,NUCB1,TIMP3,TLE1,NRG1,CABIN1,IRF7,PLD1 |
| 7.142e-03 | -4.94 | regulation of kidney development | biological process | GO:0090183 | 54 | 12 | 16441 | 1675 |
PDGFA,HOXB7,LGR4,FAT4,BMP7,SOX9,RET,TACSTD2,SOX8,OSR1,PDGFB,SIX4 |
| 7.142e-03 | -4.94 | endothelial cell migration | biological process | GO:0043542 | 54 | 12 | 16441 | 1675 |
NOV,SCG2,PTEN,NR4A1,PIK3CA,TGFBR1,LOXL2,EPHB4,EMP2,S100A2,CYP1B1,GPLD1 |
| 7.171e-03 | -4.94 | mitotic cell cycle phase transition | biological process | GO:0044772 | 297 | 44 | 16441 | 1675 |
CCNE2,CEP70,FOXM1,PSME2,CIT,EPS8,PSMD10,PSME1,CCNB1,PRKACA,CDKN2C,CCND1,WEE1,E2F7,PSMD1,CNTRL,CEP78,NEK2,PLK4,TUBG1,CDKN1B,IQGAP3,CDKN2D,PLK1,PSMB4,MYBL2,PRKAR2B,PKMYT1,BORA,PSMA4,CDK1,OPTN,PRIM1,PLK2,CDCA5,ABCB1,AURKA,KLF11,CEP41,NDE1,CCNB2,UBE2C,PPP2R2D,MELK |
| 7.173e-03 | -4.94 | PLC beta mediated events | REACTOME pathways | R-HSA-112043 | 46 | 11 | 8202 | 867 |
CALM2,PLA2G4A,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2 |
| 7.179e-03 | -4.94 | dendrite | cellular component | GO:0030425 | 412 | 57 | 17570 | 1756 |
LAMP1,ANXA3,SORT1,LMTK3,CPEB4,EPHA4,RET,LRP4,FBXO2,LYNX1,SLC1A3,HDAC6,DNER,GRM5,NCS1,NOV,ADORA1,IGSF9,MLPH,ANKS1B,PTEN,IL6ST,CABP1,DPYSL2,DAB2IP,CTTN,DLG3,DPYSL5,SGCE,ZWINT,GRIN1,PRKAR2B,ELK1,MAPK8IP1,ARF4,CDK5R1,STX3,GABARAPL1,GNAS,PIAS3,TRIM9,MAP2,KCNK1,PLK2,WFS1,SLC9A6,SIPA1L1,ARRB1,GRIN2D,NRG1,GPER1,ITPKA,RGS14,SEMA3A,NRGN,COBL,LZTS1 |
| 7.211e-03 | -4.93 | REACTOME_GAB1_SIGNALOSOME | MSigDB lists | REACTOME_GAB1_SIGNALOSOME | 36 | 9 | 17758 | 1761 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,PHLPP1,GAB1 |
| 7.211e-03 | -4.93 | phosphatidylinositol binding | molecular function | GO:0035091 | 194 | 31 | 16491 | 1673 |
MTM1,ARAP2,ARAP3,AKT1,IQGAP1,AMER1,ITPR2,ITPR3,FAM21C,SNX12,ZFYVE9,SYTL2,ZFYVE16,SNX18,WIPI1,PASK,ITPR1,SGK3,PLEKHF1,SNX16,DAB2IP,PIK3C2B,PLD1,PXDC1,SNX10,WDR45B,NRGN,CCDC88A,SNX30,ESYT2,SNX7 |
| 7.215e-03 | -4.93 | skin-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-malignant_melanoma-acral_lentiginous | 30 | 8 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,ERBB2,IDH1,GNA11 |
| 7.215e-03 | -4.93 | lentigo_maligna | COSMIC cancer mutations | lentigo_maligna | 30 | 8 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,GNA11 |
| 7.215e-03 | -4.93 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | 30 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,IDH1,GNA11 |
| 7.217e-03 | -4.93 | positive regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070304 | 132 | 23 | 16441 | 1675 |
MAP3K3,RIPK2,FZD4,EPHA4,PKN1,MAP3K6,FGF19,FZD7,CTGF,ANKRD6,NOD2,MAP3K9,DAB2IP,MDFIC,FZD5,MAP3K5,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI,XDH |
| 7.217e-03 | -4.93 | cell maturation | biological process | GO:0048469 | 132 | 23 | 16441 | 1675 |
REC8,HES1,RUNX2,CDKN1C,EPAS1,IL15,RET,CNTNAP2,CCNB1,PRKACA,RPS6KA2,BFSP1,GATA2,AXL,LHX6,PTBP3,NR4A2,NTN4,HOXB13,GDF11,SOX8,FZD5,FARP2 |
| 7.250e-03 | -4.93 | EPHA-mediated growth cone collapse | REACTOME pathways | R-HSA-3928663 | 34 | 9 | 8202 | 867 |
EPHA10,MYL9,RHOA,EPHA4,EFNA5,EPHA1,MYH14,YES1,MYL12B |
| 7.250e-03 | -4.93 | squamous_cell_carcinoma | COSMIC cancer mutations | squamous_cell_carcinoma | 17441 | 1737 | 17775 | 1757 |
HECA,AK7,SLC25A13,HEXB,RET,TGOLN2,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,MUC4,UBE2T,PAQR5,CLDN4,CRY2,TMEM37,RNF26,TIAM1,TIPARP,MGAT5,DNAAF3,FBXL16,CDA,TMEM151A,TFAP2C,PRKAR2B,RNF19B,ABR,ARF4,PIAS3,ENPP1,PLCG1,CARHSP1,MID1IP1,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,ITPKA,HSPB1,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,RANBP1,PCYOX1,MAP3K9,CADPS2,ALPK1,PANX2,ZMYM1,MYLIP,ULBP2,DGKG,NUP85,PPP6R1,MCCC2,PAQR7,HPS3,PQLC3,ELK1,NPHP3,PCTP,SFXN5,PSMA4,GNA11,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,CLMN,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,C5orf30,GRK6,MGST2,REPS1,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,SNX10,SZRD1,TMEM200B,MX1,SEC61B,COL6A2,C6orf1,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,HTATIP2,DNAJB14,XRCC6BP1,GTF2A2,ZNF618,SNX12,GABARAPL1,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,CKAP2,ESRP1,HABP4,SDC4,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,BEX2,SGPL1,CTNNBIP1,DIRAS3,FUT2,ITGB8,IGSF9,MGAT4A,CST3,FAM20B,BAX,KLC3,ZFAND4,FAM102A,IGFBP2,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,CNTNAP1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,DBI,PPM1H,ITGAV,OSR1,CMPK2,ACOT7,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,NENF,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,RPS6KA2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,ARFRP1,SESN1,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,MYL12B,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,AHCY,SELK,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,CDK5R1,PRX,RASGRP2,FOXD2,COL13A1,KBTBD2,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,USP43,HOXB7,CTDSPL,TMX4,TP53,EMP2,STIL,BCAP31,SYTL2,IER3,PDGFA,TTC21B,WDR44,LMO4,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,EFNA5,IRF7,SYT13,ST3GAL1,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,KLHL13,HAL,CDCA8,ERI2,GTF3A,GDF15,HMGN3,LBR,AIP,VPS26A,PARM1,H1FX,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,CDK16,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,TSPAN13,ALDH7A1,SYK,ATP2B1,GCNT1,WBP5,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,SMTNL2,SCG2,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,SLC9A7,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,SCOC,TBC1D1,TMEM55B,TNFRSF19,S100A2,TSPAN7,PSIP1,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,RPL39,AIM1,PPP4R1,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,NPC2,ATP8B3,ANTXR1,NFIB,MMP15,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,MATN2,FAM83D,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCTN2,DLGAP5,REPS2,ST14,CCDC110,THRA,DDIT4L,RALBP1,ATP2C2,FTH1,BCL2L1,TMEM170B,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,NOV,ACAP2,TRANK1,BRI3,EPHB4,PDE4D,TSPAN1,SULT2B1,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,ITPR3,ASB13,ALCAM,ATP10D,FZD7,AMZ2,DDOST,POPDC3,NGFRAP1,CCDC149,TSPAN18,TRIOBP,ZNF704,FAM195A,SLC27A3,PRR15,COBL,CBX7,IER5L,IGFBP6,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,EFHD2,PBX3,FBXO6,DNAH3,EFNB1,FGF19,HLA-A,WWP2,SLC25A36,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,FUT8,FJX1,DRAM1,CD9,CCDC82,ERBB3,CITED2,SLC16A5,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,ABCB1,ERAP1,WDR62,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UGT8,CRYM,VARS2,MPP5,ERP29,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,SIPA1L2,HSF2,ARHGEF37,METTL7A,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,SP5,LAMP3,CYP1B1,NLRP4,CENPA,ITCH,USP18,RGAG1,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,ZNF165,CAB39,SP6,GLA,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,B3GALNT1,COL6A1,LIMCH1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNX7,MDFI,TPGS2,ELK3,PODXL2,VWA1,PDE5A,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,UAP1,TMEM30A,SH3BP4,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,AFAP1,RARG,SNX30,LMO7,CCNE2,NCKAP5,DYNLRB1,LZTFL1,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,FABP6,REEP1,DIXDC1,EPB41L4B,ECE1,CKS2,SEPHS1,PTPRU,C3orf52,GLO1,CD40,FANCE,CASP4,ARHGAP35,SOCS3,ALDH5A1,SECTM1,PTBP3,TLE1,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,B3GALT6,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,TCEAL8,LEPR,FOXL1,ENDOD1,ARHGAP24,SWAP70,TRIM69,RND3,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CA8,BARD1,EPDR1,CALM2,DAPK2,WEE1,PSMD1,AP1M2,PQLC2,KIAA1107,CYP2S1,CABP1,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,TINAGL1,PIK3CD,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,CYP4F3,COL12A1,PGF,DNM1L,ANKRD6,LIMK1,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,GAB1,E2F8,HOXC13,NFKBIE,FAM169A,ALDH6A1,SOX9,SLC36A4,MERTK,LMNA,RAVER2,ELF3,GNS,FAM189A1,FAM13B,NEK2,NCAM1,NDUFA12,C9orf72,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,TP53INP2,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NCOA3,SEMA4D,TIMM8A,SETD3,ITPR1,AURKA,MDH1,FBXO27,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,ENPP4,CAMSAP3,SSH3,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TNRC6C,NKX3-1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,GSTP1,ARHGEF40,ETS1,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CXCL16,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,CALD1,ALG13,PLEKHF1,ADAM15,TMBIM6,ECI2,NKAPP1,MAPK11,WWP1,NPTXR,SGCB,TPCN1,S100A6,CRTAP,AMOTL2,LCA5,FAM160A1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,MYEOV,BLVRA,NEURL1B,SNTB1,CRISPLD2,PITX2,GALNT3,ACVRL1,NR1D2,CENPE,FHL1,HMGA1,USF2,DCBLD1,CYBRD1,MYL9,UNKL,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,NUP62CL,PDGFB,SDC1,CNTRL,SHC3,MKRN3,ELF5,DUSP10,ANO4,TLN2,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,KLK6,PRKRA,ANLN,IDH1,LHFPL2,ZBTB7B,RHEB,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,UBASH3B,ZCCHC24,HLA-F,ASAH1,CNTNAP2,B4GALT4,C3orf18,DHRS3,IL18R1,DAZAP1,IGF1R,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,ANKRD29,G2E3,EPN3,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,RNF146,NIPA1,AVPI1,NF2,UGP2,UPF3B,FOXM1,XYLT1,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,CYP26A1,RAD23A,ABRACL,ATP6V0B,EFR3A,N4BP3,PLCG2,LHX6,SRR,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,PRRT4,C19orf66,PTK7,ADAMTS14,ANXA9,C1orf43,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,CD63,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,SELL,PSMD10,NKRF,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,ABCD1,BUB1,KLF9,FAIM,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PPARA,CCDC34,PELI3,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,TAP1,PPFIBP2,PLXNA1,CCNB1,FAM101B,SLC20A1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,RCAN3,SMYD5,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,PIF1,GALNT7,MCFD2,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ARHGEF26,AHRR,HLF,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,LZTS1,DDX58,MRPL44,CDK17,FRMD4A,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,SLC1A3,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,RIMS2,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,FADS2,B3GNT7,MFI2,MMD,ZNF84,TBC1D8B,MICB,AMER1,ANO6,PIP4K2C,VEZT,FAM133B,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,FRMPD3,PLA2G4A,SLC2A4,ARMCX3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,IQGAP1,RPS6KA1,KCTD12,RNF182,CD274,SNN,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FAM46A,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,LYRM1,SLC11A2,PRKCQ,C15orf39,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,EPHA10,PPP2R5A,JAK1,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,DENND5B,WASF3,NUDT6,ARHGEF3,PCOLCE,ATP9A,ARL4C,CCNJL,CYB561,APOBEC3H,SEPP1,SPR,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,AKIRIN1,FAM111A,PHF7,PTEN,SGK3,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,SPRY2,TRIM62,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,MAMDC4,AMMECR1,CSTF2,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,CPT2,FLYWCH2,CAMKK1,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,SUN3,RAB20,RP2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,ROR1,PTGFRN,MRPS36,ADRBK2,STK17B,EDNRA,MDK,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,ADIPOR1,LEMD1,RAP1GAP,CPPED1,STARD3NL,GRN,FAM213B,LRRFIP2,PEX6,SAMD9,PHLPP1,OTUD1,ZNF432,AIM1L,CA2,KCNN4,FXYD5,RFX5,SIMC1,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,GAS2L1,SLC25A24,SPC25,FAM92A1,IL15,PSME2,MORC4,TDRKH,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,FRYL,RPN2,TWIST1,GOT1,PDIA6,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,KCTD2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,REEP4,PPP2R2D,LIFR,ANXA3,SORT1,POC1B,FRMD6,LRP4,ARMC7,FAM134A,MIER3,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,IQGAP3,SYPL1,SUN2,RAB3B,NR4A1,DEPDC4,GCLC,ASPM,OGDHL,MBNL3,LRRC66,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,DHRS2,OTUB2,HOXB13,SOX8,GEM,L1CAM,SNPH |
| 7.250e-03 | -4.93 | single-organism cellular localization | biological process | GO:1902580 | 906 | 115 | 16441 | 1675 |
MTM1,DLGAP5,NDC80,TP53,PKP2,F11R,MPP5,SYTL4,CCNB1,EMP2,ZFYVE9,SYTL2,ZFYVE16,RAB15,CDH1,ZDHHC12,KIF14,DPYSL2,REEP1,BCL6,DLG1,ZDHHC23,SNX16,RPN2,PIK3CD,LMAN1,DLG3,PACSIN1,RAB27B,TRAM1,F2R,S100A13,RASGRP1,ATG4D,SEC23A,KCNIP3,SEC61B,CENPA,AKT1,SYNE2,EZR,ARFRP1,KIF13A,NUSAP1,ATP1B1,RAB38,ICMT,MCFD2,DAG1,OPTN,TRIM9,DDOST,GNPTAB,PEX2,SYT13,GRN,TSPAN15,PEX6,LRP4,ETV5,CDCA8,PDIA3,CTSZ,RAB6A,GPSM2,AIP,LMNA,ATG4A,ZDHHC21,KIF5B,ADORA1,CTSC,LLGL2,GATA2,RPL39,BAX,PLEKHF1,SORL1,SYK,SYTL3,NUP85,PPP6R1,SPRY2,MYO5A,SUN2,HES1,PMPCB,RAB3B,CRB3,ASPM,RAPGEF2,PIK3R1,PRICKLE1,SCRIB,COL7A1,BBS2,STX3,SCARB2,RPL12,SERPINA1,FGFR2,TIMM8A,SYT7,NFKBIA,CDCA5,NR4A3,ZDHHC7,SPCS3,ATP1B3,CENPE,NDE1,JAK3,TOB1,ESPL1,SNPH |
| 7.285e-03 | -4.92 | regulation of protein secretion | biological process | GO:0050708 | 388 | 55 | 16441 | 1675 |
EXPH5,LGR4,HLA-E,IQGAP1,CACNA2D2,HMGN3,ITPR2,SYTL4,CD274,PRKACA,FBLN1,SLC8B1,ERP29,ANO1,NEO1,NOV,CARD8,LLGL2,CDK16,KCNN4,KCNS3,TMBIM6,MAPK11,TWIST1,CACNA1D,MYRIP,F2R,MYT1,SYK,RASGRP1,ACVR1C,SYBU,PTGER4,RGCC,EZR,PRKCQ,PRKAR2B,ITPR3,CD40,SLC25A5,GPLD1,GNAS,IRS2,BANK1,SLC25A4,DNM1L,SYT7,ITPR1,RAB11FIP1,NOD2,ARRB1,EFNA5,GPER1,SPCS3,F2RL1 |
| 7.309e-03 | -4.92 | CELLULAR_MACROMOLECULE_METABOLIC_PROCESS | MSigDB lists | CELLULAR_MACROMOLECULE_METABOLIC_PROCESS | 1113 | 135 | 17758 | 1761 |
CASP3,GAA,SIGIRR,SSH1,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,DAPK2,IL31RA,FUT1,DUSP10,RP2,PTPRE,METAP2,TNIP1,GALNT7,LOXL2,ANLN,ICMT,STK17B,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,BMP1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,PEX6,DNAJB2,MERTK,TSPAN7,RABGGTA,ATG4A,B3GALNT1,IGF1R,PAIP2B,RPL39,TBCD,MAP3K9,DAPK1,TPST1,PRKG1,PIM1,MYLIP,GAD1,CCDC88A,DDB2,MGAT4B,STRADB,EIF2AK1,NUBP1,RASA1,GLCE,STK17A,MAPKAPK2,MMP15,AURKA,JAK3,NF2,ST14,HDAC11,PDIA5,TESK2,ERBB2,ZFYVE9,CCND1,PLK4,RPN2,LMAN1,PHKA2,PDIA6,F2R,ATG4D,SEPHS1,MAP3K3,SIRT1,AKT1,COG2,PTPRU,PTPN9,CDC20,DUSP4,MAP3K6,CASP4,IDE,PTPRJ,STK38,NRG1,HS3ST3B1,MAPK12,WASF3,PINK1,CTSZ,TGFBR1,FBXO6,POMGNT1,SBF1,TRIB2,PKN1,AIP,PPP2R3A,WWP2,FUT2,CDK16,PTEN,MGAT4A,FUT8,RRBP1,SGK3,SGK1,WWP1,ERBB3,GCNT1,AMFR,UBE2A,FURIN,PARP4,YES1,PRDX4,PLOD2,ACVRL1,NR4A3,ERAP1,HMGA1,PLOD3,UBE2C,HIPK3,ABCG1 |
| 7.310e-03 | -4.92 | recycling endosome | cellular component | GO:0055037 | 127 | 22 | 17570 | 1756 |
MYO5B,AMOTL2,PACSIN2,ATP9A,PANK1,SLC11A2,SLC9A7,OPTN,RAB11FIP2,KCNK1,SLC9A6,RAP2C,RAB11FIP1,SGK3,TUBG1,SORL1,GPER1,ARF6,MYO5A,GPR161,ABCG1,EHD1 |
| 7.339e-03 | -4.91 | PTEN_DN.V2_UP | MSigDB lists | PTEN_DN.V2_UP | 128 | 22 | 17758 | 1761 |
ANXA3,SLC2A4,KLK10,PQLC3,ARL4C,UTRN,ARHGDIB,SLC1A3,LOXL2,TRIB2,TP53I3,CASP4,CTNNBIP1,COL13A1,CSF1,SECTM1,ALDH1A3,OTUB2,ARVCF,CLIP4,CEP41,OSGIN1 |
| 7.339e-03 | -4.91 | chr1q32 | MSigDB lists | chr1q32 | 128 | 22 | 17758 | 1761 |
CD55,PLEKHA6,ASCL5,ZC3H11A,SERTAD4,CR2,NENF,RNPEP,ELF3,SOX13,MAPKAPK2,ADORA1,PPP2R5A,UBE2T,KIF14,NEK2,YOD1,ADIPOR1,PIK3C2B,LEMD1,TRAF5,DDX59 |
| 7.355e-03 | -4.91 | VALK_AML_CLUSTER_15 | MSigDB lists | VALK_AML_CLUSTER_15 | 30 | 8 | 17758 | 1761 |
TNS3,ARHGEF3,HOXA9,DRAM1,KLF9,HSPB1,NDFIP1,HOXB2 |
| 7.355e-03 | -4.91 | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 30 | 8 | 17758 | 1761 |
IGFBP6,SEMA4D,LITAF,PIM1,PKN1,IDH1,RARG,IER3 |
| 7.355e-03 | -4.91 | PID_CDC42_REG_PATHWAY | MSigDB lists | PID_CDC42_REG_PATHWAY | 30 | 8 | 17758 | 1761 |
BCAR3,PLCG1,RALBP1,SPATA13,ARHGEF9,DOCK9,FGD1,FARP2 |
| 7.381e-03 | -4.91 | regulation of cytokine production | biological process | GO:0001817 | 549 | 74 | 16441 | 1675 |
SIGIRR,LGR4,NLRX1,IL15,INPP5D,IQGAP1,NDRG2,IL27RA,F11R,IL18,CD274,TNFSF9,IL6ST,ZFP36,PLCG2,BCL6,CDH3,TWIST1,PDE4D,F2R,RASGRP1,CYP1B1,SULF2,NLRP4,RIPK2,ITCH,PTGER4,EZR,PRKCQ,CD40,GPRC5B,HPSE,AGPAT2,AXL,TRAF3IP1,NOD2,IRF7,F2RL1,HSPB1,DDX58,HLA-E,HERC5,TRIB2,FBLN1,GSTP1,IL18R1,HLA-A,CARD8,RNF128,UBE2J1,TRIM21,MAPK11,C10orf54,WNT3A,SYK,PIK3R1,FURIN,RGCC,LITAF,CD83,MAPKAPK2,HLA-B,BANK1,NFKBIA,NMI,DTX4,NR4A3,NLRC5,ARRB1,FZD5,IFIH1,JAK3,NDFIP1,TMEM173 |
| 7.392e-03 | -4.91 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 231 | 35 | 17758 | 1761 |
CD99,TXN,TP53,COL4A5,BCL2L1,SLC20A1,PDGFB,ETS1,SIRPA,ELF3,HDAC9,CALD1,BHLHE41,ALDH1A3,CDKN1B,SORL1,IGFBP2,PIM1,CITED2,PGM1,NR3C1,NR4A1,PLAUR,SAT1,PPARA,PDK3,FOS,CDK1,PGF,SLC6A6,PLOD2,SYT7,P4HA2,ABCB1,HDAC1 |
| 7.415e-03 | -4.90 | human chrXq22.2 | chromosome location | human chrXq22.2 | 18 | 5 | 26250 | 1887 |
FAM199X,NGFRAP1,TMSB15B,WBP5,TCEAL4 |
| 7.441e-03 | -4.90 | neural tube development | biological process | GO:0021915 | 155 | 26 | 16441 | 1675 |
TGIF1,HES1,CTHRC1,GRHL2,ST14,SALL4,SDC4,RAB23,PRICKLE1,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,SHROOM3,PTK7,LMO4,SPINT2,TRAF3IP1,TWIST1,PLOD3,WNT3A,COBL,RARG,DVL2 |
| 7.447e-03 | -4.90 | TBK1.DN.48HRS_DN | MSigDB lists | TBK1.DN.48HRS_DN | 49 | 11 | 17758 | 1761 |
PDGFA,ANKRD10,DCK,INPP4B,IL13RA1,PRKCQ,DUSP4,GTF2A2,H2AFV,CDK1,IER3 |
| 7.447e-03 | -4.90 | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | MSigDB lists | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | 49 | 11 | 17758 | 1761 |
AMOTL2,CDKN2C,PCOLCE,FBLN5,CTGF,PLOD2,IL6ST,LTBP2,ATP1B1,SEPP1,DDR1 |
| 7.484e-03 | -4.89 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | 167 | 27 | 17758 | 1761 |
AMOTL2,ARAP2,IL15RA,PLSCR1,AASS,CRYM,HERC5,COL7A1,SAMD9,IFIT3,HERC6,TNFRSF19,SYTL2,TMCC3,OTUD1,FAM111A,C19orf66,NLRC5,NRG1,IRF7,HS3ST3B1,IFIT1,OAS3,CMPK2,FBXO27,GLCCI1,RARG |
| 7.484e-03 | -4.89 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | 167 | 27 | 17758 | 1761 |
SUN1,PRKAA2,UNKL,CHCHD7,FAM199X,DNAJC3,ITGA6,EPHA4,MBNL3,PLXNA1,ABCD4,SCML1,TMEM63A,PGF,HS6ST1,IGF1R,STK38,MGAT4A,FAM13B,FAM63A,SORL1,ZMYM1,ZNF502,NDFIP1,ALS2CL,NR3C2,CBX7 |
| 7.487e-03 | -4.89 | protein tyrosine kinase binding | molecular function | GO:1990782 | 48 | 11 | 16491 | 1673 |
DOCK4,PLCG1,ELMO2,SHC3,PIK3R1,LRP4,TP53,NRG1,TOB1,ARHGEF16,SOCS5 |
| 7.493e-03 | -4.89 | ACEVEDO_LIVER_CANCER_UP | MSigDB lists | ACEVEDO_LIVER_CANCER_UP | 913 | 113 | 17758 | 1761 |
SUN1,DYNLRB1,TRIM2,IQGAP1,TAP1,PKP2,F11R,ITPR2,MORF4L2,CENPN,CARD10,PLS3,BTG3,TYMP,UBE2T,METTL7A,XYLT2,IMPAD1,DOK4,PAPSS1,ZDHHC23,RPN2,MARCH2,TMEM37,MINPP1,LRP11,RNF26,PDIA6,MYRIP,TMEM9,SEPHS1,FRS3,CKS2,SEMA3B,ERLEC1,KIFC2,SLC39A8,CDC20,KIF1C,NUSAP1,MCFD2,RHEB,LRRC42,IRS2,PLCG1,HLF,PPP2R5A,RBM47,WIPI1,SHROOM3,P4HA2,SLC9A6,PEX2,PRKCDBP,ADIPOR1,MRPS28,HSPB1,GRN,MRPL44,SORT1,SCOC,HLA-E,HLA-F,BLVRB,ARMC7,PSMD10,INTS8,SLC1A3,NUCB2,HERC6,NTAN1,ETS1,TIPRL,VPS26A,SCML1,UBE2Q2,CD9,ADAM15,RFX5,TAGLN2,HLA-C,CNPY3,MYLIP,OSGIN1,HES1,PDGFC,PRODH,MRPS33,TESK1,ASPM,LPGAT1,BTN3A2,GGH,BLVRA,PCTP,AMDHD1,DCP2,KLHL2,HLA-B,SWAP70,UAP1,TIMM8A,UTP14C,ABCB1,FAM83D,AURKA,CSTF2,ITGAV,SERPINB1,TMEM14A,CYBRD1,ZBTB33,JARID2 |
| 7.497e-03 | -4.89 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | 762 | 96 | 17775 | 1757 |
LTBP1,SPRED1,NF2,GRHL2,ADD1,SSH1,REPS2,HSPG2,AASS,NLRX1,RET,FHDC1,TP53,COL18A1,ERBB2,VARS2,SPTB,EPDR1,CDKN2C,ALDH1A3,PLCG2,FOSB,KCNS3,PIK3CA,ABCA2,SUN3,EPB41L4B,NOTCH3,PIK3CD,NEB,ERAP2,CAMSAP3,AKT1,PTPN9,DRAP1,IDH1,COL12A1,DPYSL3,PRDM11,SOCS3,IRS2,JAK1,SHROOM3,AXL,TLE1,PIK3C2B,NRG1,DENND5B,ARHGEF11,ATP9A,HABP4,ANO9,SBF1,SEPP1,SRPX2,TFAP4,TNS3,IGF1R,PTEN,GATA2,FRAS1,FUT8,ALPK1,PIM1,CLIP2,PLCB2,SPRY2,GPR161,FAH,RASGRF1,PDGFC,HES1,SUN2,ZWINT,RAPGEF2,AMER1,MRS2,PIK3R1,MYBL2,TCF7,COL7A1,PRX,NCOA3,SCARB2,UAP1,NR1D2,FGFR2,CDCA5,NLRC5,FGD6,CLMN,UACA,JAK3,SEMA3A,AFAP1,ADAMTS16 |
| 7.497e-03 | -4.89 | acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_T_cell_leukaemia | 762 | 96 | 17775 | 1757 |
LTBP1,SPRED1,NF2,GRHL2,ADD1,SSH1,REPS2,HSPG2,AASS,NLRX1,RET,FHDC1,TP53,COL18A1,ERBB2,VARS2,SPTB,EPDR1,CDKN2C,ALDH1A3,PLCG2,FOSB,KCNS3,PIK3CA,ABCA2,SUN3,EPB41L4B,NOTCH3,PIK3CD,NEB,ERAP2,CAMSAP3,AKT1,PTPN9,DRAP1,IDH1,COL12A1,DPYSL3,PRDM11,SOCS3,IRS2,JAK1,SHROOM3,AXL,TLE1,PIK3C2B,NRG1,DENND5B,ARHGEF11,ATP9A,HABP4,ANO9,SBF1,SEPP1,SRPX2,TFAP4,TNS3,IGF1R,PTEN,GATA2,FRAS1,FUT8,ALPK1,PIM1,CLIP2,PLCB2,SPRY2,GPR161,FAH,RASGRF1,PDGFC,HES1,SUN2,ZWINT,RAPGEF2,AMER1,MRS2,PIK3R1,MYBL2,TCF7,COL7A1,PRX,NCOA3,SCARB2,UAP1,NR1D2,FGFR2,CDCA5,NLRC5,FGD6,CLMN,UACA,JAK3,SEMA3A,AFAP1,ADAMTS16 |
| 7.545e-03 | -4.89 | GSE2706_2H_VS_8H_R848_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_DN | 175 | 28 | 17758 | 1761 |
PLA2G4A,DDX58,DOCK4,TXN,MACC1,HAPLN3,ITCH,ETV5,HERC5,HMGN3,DUSP4,DTX3L,ARHGAP24,TNS3,PRKAG2,ITGB8,PLOD2,NMI,PIK3CA,ACSL4,CMPK2,TBC1D4,SHROOM2,SCYL3,IFI6,APOBEC3G,IGSF3,PARP9 |
| 7.547e-03 | -4.89 | regulation of T cell proliferation | biological process | GO:0042129 | 140 | 24 | 16441 | 1675 |
HES1,CASP3,CD55,RIPK2,LGALS3,IL15,ITCH,HLA-E,PDE5A,ERBB2,IL18,PRKCQ,CD274,TNFSF9,EFNB1,HLA-A,IL6ST,DLG1,IGFBP2,C10orf54,ICOSLG,NDFIP1,JAK3,SYK |
| 7.550e-03 | -4.89 | odontogenesis | biological process | GO:0042476 | 103 | 19 | 16441 | 1675 |
SCN5A,RUNX2,NF2,ITGA6,LRP4,PPARA,OSR2,SDC1,PITX2,CA2,STIM1,FGFR2,BMP7,BAX,HDAC1,CNNM4,TWIST1,OSR1,MYO5A |
| 7.572e-03 | -4.88 | QI_HYPOXIA | MSigDB lists | QI_HYPOXIA | 136 | 23 | 17758 | 1761 |
PGM1,SOX9,PKP2,NDRG2,IL13RA1,TNFSF9,ZNF469,COL12A1,IER3,PGF,CD109,HPSE,PLOD2,CYP2S1,P4HA2,REEP1,TRIOBP,ESPN,DIXDC1,OSTF1,EGLN3,SLC27A3,EGLN1 |
| 7.580e-03 | -4.88 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | 183 | 29 | 17758 | 1761 |
PGM1,LZTFL1,HES1,SORT1,COL6A2,RASA2,SYBU,PIK3R1,GABRG2,SPTLC2,STK17B,TRIM68,RASA1,HDAC9,MAPKAPK2,TFAP4,CTSC,PLOD2,LLGL2,SEMA4D,PTER,PHTF1,AMMECR1,FOSB,SRR,NR4A3,NR4A2,MDFIC,KLF9 |
| 7.580e-03 | -4.88 | GSE3982_MAST_CELL_VS_MAC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_DN | 183 | 29 | 17758 | 1761 |
EPAS1,GUSB,RC3H2,AK4,IL13RA1,TGFBR1,IL27RA,TEX2,FAM198B,BCL2L1,NANS,DNAJB14,ALCAM,PPP2R3A,RHEB,OPTN,PLS3,EPCAM,ATP1A1,ITGA3,RBL1,CDK16,GALNS,MITF,AOX1,CLIP4,ZDHHC7,TNFRSF12A,RP2 |
| 7.580e-03 | -4.88 | HAMAI_APOPTOSIS_VIA_TRAIL_DN | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_DN | 183 | 29 | 17758 | 1761 |
ARAP3,RPS6KA1,PLAUR,GRIN1,ERBB2,KLK6,GDF15,ISYNA1,F12,FBLN1,TP53I3,H1FX,SAC3D1,FOXD2,MDK,PTPRF,TYMP,SLCO4A1,TIMP3,SH3BP1,DHRS2,COL6A1,FXYD5,ARRB1,TAGLN2,FZD5,SERPINB1,SLC16A5,DEF6 |
| 7.580e-03 | -4.88 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | 183 | 29 | 17758 | 1761 |
CCNE2,PRODH,UGT8,CDC20,SYBU,PTTG1,GRIN1,CCDC68,CDK5R1,GALNT3,TFAP4,RCN1,PVRL2,RND3,ZNF214,DACT1,AOX1,DTX4,MAP3K9,KCNS3,ABCB1,ANKRD12,ATRNL1,TSPAN13,PLD1,EPB41L4A,SCARA3,MAST4,PKIA |
| 7.580e-03 | -4.88 | GSE3982_BASOPHIL_VS_TH1_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_UP | 183 | 29 | 17758 | 1761 |
MAN2B2,MTM1,PDGFC,SLC2A4,MBP,SORBS1,RHOA,S100A4,OSGIN2,C6orf106,PBX3,ARHGDIB,DSE,ARHGEF40,PCTP,ATP10D,SOX13,SWAP70,PPP2R5A,TRANK1,HOXA9,FAM13B,SLC4A3,BCL6,CD9,KLF9,TRAM1,CTDSP2,PCSK5 |
| 7.583e-03 | -4.88 | HSIAO_HOUSEKEEPING_GENES | MSigDB lists | HSIAO_HOUSEKEEPING_GENES | 382 | 53 | 17758 | 1761 |
LAMP1,CCNI,LASP1,TXN,LGALS3,CD63,IQGAP1,CAST,HLA-E,AES,NDUFA4,FTH1,PSME1,MORF4L2,MGST2,COX6C,GSTP1,BCAP31,HLA-A,APLP2,ZFP36,RPL39,CST3,TMBIM6,RPN2,TAGLN2,PIM1,NDUFA12,CTDSP2,GPX4,SEC61B,RHOA,PSMB4,GUSB,EZR,ARHGDIB,NPC2,SLC25A5,NFIB,ARF4,FAS,GNAS,FUCA1,RPL12,NFKBIA,HDAC1,SERPINB6,MDH1,FHL1,ARPC2,UBE2C,LTA4H,HSPB1 |
| 7.585e-03 | -4.88 | SIRNA_EIF4GI_UP | MSigDB lists | SIRNA_EIF4GI_UP | 91 | 17 | 17758 | 1761 |
SUN2,PMPCB,NQO1,INPP5D,FXYD3,ASAH1,PSME1,SLC25A5,DAG1,HLA-B,ATP1A1,CA2,CTSC,PAPSS1,DTX4,ALDH7A1,HSPB1 |
| 7.592e-03 | -4.88 | response to oxidative stress | biological process | GO:0006979 | 339 | 49 | 16441 | 1675 |
CASP3,GCLM,SLC25A24,TXN,PINK1,NQO1,EPAS1,ETV5,TP53,HDAC6,SEPP1,ETS1,SDC1,GSTP1,PSIP1,CST3,AKR1B1,SELK,SCARA3,NDUFA12,CYP1B1,GPX4,SIRT1,PPIF,PRODH,AKT1,GCLC,MICB,OXR1,ERO1A,NFE2L1,SLC11A2,PRKRA,IDH1,FOS,DUOX1,ALDH3B1,NEIL1,STK26,DHRS2,NR4A3,OSER1,NR4A2,RGS14,MAP3K5,CPEB2,GAB1,MELK,EGLN1 |
| 7.592e-03 | -4.88 | BOQUEST_STEM_CELL_UP | MSigDB lists | BOQUEST_STEM_CELL_UP | 256 | 38 | 17758 | 1761 |
PLA2G4A,PCOLCE,MRC2,SERPINE2,IGFBP6,GALNT12,SOX9,OSR2,CRABP2,DSE,FBLN1,CDKN2C,BHLHE41,MITF,COL6A1,AOX1,TWIST1,ACOX2,SCARA3,FAM69A,SGCE,COL6A2,FBLN5,MBP,CAPN6,S100A4,ROR1,GLT8D2,STEAP1,FZD7,CRISPLD2,IRS2,PDLIM3,KCNK1,AXL,LTBP2,COL16A1,CYBRD1 |
| 7.593e-03 | -4.88 | KRAS.DF.V1_DN | MSigDB lists | KRAS.DF.V1_DN | 191 | 30 | 17758 | 1761 |
PRSS8,BCAM,KLK5,SLC25A13,PCBP3,RET,COL4A5,HMGN3,FANCE,STX3,NRP2,SIRPA,HDAC9,PDGFA,CYP1A1,ETS2,TJP3,PHF7,ALG13,FAM63A,CDK18,KLF11,IGFBP2,EPB41L4B,SCN2A,AHR,COBL,RAB3IL1,ATP2B1,LAMP3 |
| 7.593e-03 | -4.88 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | 191 | 30 | 17758 | 1761 |
MYO5B,NQO1,USP18,DIAPH2,IL27RA,ICMT,FAM101B,FOS,BSDC1,SOCS3,AKIRIN1,IRS2,CTNNBIP1,ENPP1,ST5,RPS6KA2,CA2,COQ10A,NR1D2,AKR1B1,SORL1,SLC27A1,IRF7,NOTCH3,TMEM159,ZRANB1,ABCA1,JARID2,ABCG1,SOCS5 |
| 7.593e-03 | -4.88 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | 191 | 30 | 17758 | 1761 |
HMMR,PRSS8,CDK17,NF2,PRSS23,S100A11,SLC39A8,ATP9A,CENPI,PLAUR,SAT1,SLC11A2,HMGN3,SNTB1,FZD6,CDK5R1,OPTN,IER3,IRS2,BTG3,JAK1,ETS2,FUT2,CDK16,NFKBIA,CLDN4,CDKN2D,IFI6,AFAP1,LAMP3 |
| 7.593e-03 | -4.88 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | 191 | 30 | 17758 | 1761 |
CASP3,MTM1,SORBS1,ALDH2,LGALS3,IFITM3,MRPS15,AMFR,LITAF,CDCA8,LACTB2,CD40,DOCK5,TP53INP2,ALCAM,GABARAPL1,AHRR,GALNT3,PIAS3,ENPP1,CARHSP1,SWAP70,CA2,IGF1R,TWSG1,CD9,CTSA,ITGAV,SYK,JARID2 |
| 7.593e-03 | -4.88 | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | 191 | 30 | 17758 | 1761 |
GRN,LAMP2,AVPI1,ST14,S100A11,CD63,GCLC,SH3BGRL,DCAF7,UBE2A,NFE2L1,IDH1,GSTP1,RHEB,M6PR,ATP6V0B,C7orf49,CTSC,GDE1,UTP14C,PLCG2,CST3,DAPK1,OPN3,GLA,ZMIZ1,NRGN,SYK,ALDH3A2,ISOC1 |
| 7.593e-03 | -4.88 | GSE3982_DC_VS_TH2_DN | MSigDB lists | GSE3982_DC_VS_TH2_DN | 191 | 30 | 17758 | 1761 |
HMMR,ARHGAP11A,SPC25,KIF20A,SERPINE2,DLGAP5,MRPS15,SYNE2,PTTG1,RAB23,GPSM2,CENPN,IL18R1,FANCI,ARHGAP35,GALNT3,DCTN6,DOLPP1,PASK,FAM117A,ECI2,TWIST1,TSPAN13,TAGLN2,PDE4D,DLG3,CCNB2,APOBEC3G,MPHOSPH9,SEPHS1 |
| 7.593e-03 | -4.88 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | 191 | 30 | 17758 | 1761 |
CPD,MYL9,DOCK4,BIN1,DYNLRB1,TTC39B,IFITM3,ACVR1C,ZCCHC24,INPP5D,FURIN,SPATA13,DIAPH2,TGFBR1,CD40,GLT8D2,NIN,AHRR,ENDOD1,AP1M2,PTPRJ,SLC44A1,LRIG1,RAB20,GEM,ARSB,MYRIP,MGAT5,AHR,CYP1B1 |
| 7.627e-03 | -4.88 | CYT_DCMP_DEAMINASES_1 | prosite domains | PS00903 | 13 | 5 | 11866 | 1235 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 7.659e-03 | -4.87 | response to topologically incorrect protein | biological process | GO:0035966 | 163 | 27 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,DNAJB2,AMFR,DNAJC3,ERO1A,PDIA5,DNAJB11,FBXO6,F12,HDAC6,DNAJB9,LMNA,CCND1,WIPI1,WFS1,BAX,TMBIM6,DAB2IP,YOD1,MYDGF,MANF,PDIA6,HSPB1,CTDSP2,CTH |
| 7.660e-03 | -4.87 | ETS2 (v-ets avian erythroblastosis virus E26 oncogene homolog 2) | protein interactions | 2114 | 28 | 8 | 16036 | 1726 |
NCOA3,ETS2,NR3C1,TP53,TWIST1,ETS1,FOS,ZFYVE9 |
| 7.670e-03 | -4.87 | OXIDOREDUCTASE_ACTIVITY | MSigDB lists | OXIDOREDUCTASE_ACTIVITY | 281 | 41 | 17758 | 1761 |
TXN,NQO1,ALDH6A1,BLVRB,PDIA5,CYB561,SPR,AIFM2,DHRS3,CYP39A1,CYP26A1,BDH1,ALDH1A3,AOX1,AKR1B1,ALDH7A1,ACOX2,ALDH3A2,GPX4,CYP1B1,PRODH,ALDH2,CYB5R2,BLVRA,LOXL2,IDH1,CYP4F3,POR,CYB5A,PRDX4,ALDH3B1,ALDH5A1,ACADSB,PLOD2,DHRS2,P4HA2,MDH1,PLOD3,CYBRD1,EGLN1,XDH |
| 7.698e-03 | -4.87 | response to inorganic substance | biological process | GO:0010035 | 431 | 60 | 16441 | 1675 |
SCN5A,CASP3,SLC25A24,NQO1,SLC25A13,IQGAP1,MTL5,CALM3,COL18A1,CCNB1,HDAC6,ETS1,SDC1,CALM2,CCND1,CPNE2,CYP1A1,CDH1,CA2,STIM1,PTEN,CST3,FOSB,BAX,CD9,TFAP2A,AKR1B1,TRPC1,CDKN1B,IGFBP2,LRP11,S100A13,CYP1B1,SIRT1,PPIF,CALM1,CASP9,GRIN1,ACO1,SLC11A2,GGH,LOXL2,ITPR3,FOS,CYB5A,FAS,RASGRP2,GPLD1,ATP13A2,FECH,KCNMB4,STK26,ATP7B,NR4A3,OSER1,MAP3K5,LTA4H,PTGES,CYBRD1,EGLN1 |
| 7.703e-03 | -4.87 | V$ARNT_01 | MSigDB lists | V$ARNT_01 | 248 | 37 | 17758 | 1761 |
LAMP1,ARMCX3,ALDH6A1,IL15RA,CPEB4,HOXB7,TESK2,VARS2,PDGFB,NUP62CL,BMP2K,DNAJB9,TFAP4,ATP6V0B,RNF128,BHLHE41,PLCG2,ANKRD12,CRY2,MANF,EPB41L4B,ARMCX6,ETV4,DVL2,B3GALT6,SIRT1,SHMT1,HPS3,PLEKHA6,OGDHL,C15orf39,KBTBD2,ARF6,C1orf43,ABCA1,CXorf56,RAB3IL1 |
| 7.711e-03 | -4.87 | extracellular matrix | cellular component | GO:0031012 | 422 | 58 | 17570 | 1756 |
COL9A3,LTBP1,CTHRC1,PCOLCE,SERPINE2,LGALS3,HSPG2,HAPLN3,ITGA6,P3H2,LMCD1,COL18A1,COL4A5,SLC1A3,ADAMTSL4,FBLN1,LTBP3,LGALS3BP,NOV,MUC4,CTGF,CYR61,NPNT,BMP7,FRAS1,FLRT3,CST3,COL6A1,DLG1,NTN4,TINAGL1,WNT3A,CRTAP,ADAMTS2,TIMP2,COL6A2,FBLN5,PLSCR1,VWA1,COL7A1,LOXL2,ERBB2IP,DAG1,CRISPLD2,COL12A1,GPLD1,MMP15,TIMP3,SERPINA1,FGFR2,MMP17,MATN2,BMP1,ADAMTS14,EGFL7,LTBP2,COL16A1,ADAMTS16 |
| 7.727e-03 | -4.86 | limbic system development | biological process | GO:0021761 | 96 | 18 | 16441 | 1675 |
ANXA3,CASP3,NF2,CNTNAP2,BBS2,ETS1,CDK5R1,MDK,FGFR2,PTEN,PHLPP2,KIF14,ALDH1A3,BAX,NR4A3,WNT3A,ZBTB18,SEMA3A |
| 7.739e-03 | -4.86 | positive regulation of neuron projection development | biological process | GO:0010976 | 202 | 32 | 16441 | 1675 |
GRN,FOXO6,SERPINE2,RET,EPHA4,CAMK1D,CRABP2,ITGA3,MEGF8,BMP7,TNFRSF12A,DAB2IP,PACSIN1,WNT3A,TIAM1,RIMS2,RHOA,RAPGEF2,ARHGAP35,DPYSL3,GPRC5B,SEMA4D,TMEM30A,LIMK1,PTK7,BHLHB9,NRG1,EFNA5,ITPKA,ARSB,L1CAM,COBL |
| 7.760e-03 | -4.86 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 144 | 24 | 17758 | 1761 |
ZNF395,LGR4,ZCCHC24,SOX9,GALNT7,SLC7A2,MGAT5B,NPHP3,FAM167A,SNX12,GLCE,TMCC3,B3GALNT1,C7orf49,ALDH5A1,SWAP70,FAM46A,RALGPS2,SLC44A1,FUT8,ACSL4,PKIA,CRTAP,FAH |
| 7.764e-03 | -4.86 | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | 121 | 21 | 17758 | 1761 |
GRN,PRSS8,CD55,MFI2,HLA-E,PLAUR,DNAJB2,SDC4,SAT1,TAP1,ATP1B1,ARF4,MMP15,P4HA2,RRBP1,CD9,TRIM21,TACSTD2,IFIT1,LGMN,MYRIP |
| 7.764e-03 | -4.86 | V$IRF2_01 | MSigDB lists | V$IRF2_01 | 121 | 21 | 17758 | 1761 |
DDX58,PCGF5,PDGFC,SORBS1,IL15RA,USP18,SYNE2,TAP1,RGAG1,CCDC68,PSME1,LDB2,DTX3L,TAPBP,RNF220,MITF,DLG1,FXYD5,DUSP10,NR3C2,RIMS2 |
| 7.787e-03 | -4.86 | CUB | pfam domains | PF00431 | 48 | 11 | 16629 | 1696 |
PDGFC,PCOLCE,ST14,MEGF8,BMP1,NETO2,ATRNL1,KREMEN1,DCBLD1,NRP2,TLL2 |
| 7.792e-03 | -4.85 | TGFBR2 (transforming growth factor beta receptor II) | protein interactions | 7048 | 98 | 19 | 16036 | 1726 |
IQGAP1,PIK3R1,ERBB2,SCRIB,TGFBR1,RAB6A,SBF1,CCNB1,CDK1,ZFYVE9,NRP2,PTPRF,JAK1,ACVRL1,WDR44,OSR1,NDFIP1,CCNB2,OCLN |
| 7.806e-03 | -4.85 | V$MYOGENIN_Q6 | MSigDB lists | V$MYOGENIN_Q6 | 240 | 36 | 17758 | 1761 |
EMX1,FBLIM1,SORT1,ZCCHC24,ITGA6,XYLT1,PKN1,PRKACA,SPTB,ZFYVE9,CYP26A1,CDKN2C,RNF220,STIM1,CABP1,CDH3,IQCD,TRIM62,TPCN1,IGSF3,EPB41L5,PCGF5,TGIF1,TRIM8,KCNIP3,ELK3,VWA1,IGSF8,RUNX3,ATP1B1,RNF19B,PTPRJ,AXL,UACA,OSR1,DOCK9 |
| 7.821e-03 | -4.85 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 56 | 12 | 17758 | 1761 |
IRS2,TNS3,PBK,TMX4,ARL4C,CD9,KCNS3,MORC4,SGK1,COL18A1,ARRB1,PRKAR2B |
| 7.831e-03 | -4.85 | developmental process involved in reproduction | biological process | GO:0003006 | 602 | 80 | 16441 | 1675 |
GRHL2,LGR4,EPAS1,ST14,HEXB,BCL2L1,CCNB1,SDC1,PRKACA,PDGFB,CCND1,RPS6KA2,LRRC6,PAQR5,DLG1,PLK4,TIPARP,SIRT1,SMARCA2,AKT1,FZD4,TFAP2C,PYGO1,CCNF,IDH1,SOCS3,HS6ST1,HOXA9,AXL,E2F8,GAB1,COL9A3,NKX3-1,CDKN1C,SERPINE2,CENPI,ETV5,SOX9,TGFBR1,MERTK,SIX4,SGPL1,IRF2BPL,E2F7,DAZAP1,IGF1R,ITGB8,PTEN,CYR61,GATA2,TOX2,CST3,UBE2J1,BAX,CITED2,MDFI,PAQR7,REC8,HES1,ASPM,DIAPH2,FNDC3A,BBS2,PRDX4,PITX2,NCOA3,PVRL2,FGFR2,CSF1,SPINT2,CTSV,ARRB1,HOXB13,SOX8,OSR1,FZD5,HOOK1,RARG,AHR,EGLN1 |
| 7.855e-03 | -4.85 | Adipocytokine signaling pathway | KEGG pathways | hsa04920 | 70 | 15 | 6908 | 758 |
PRKAA2,IRS2,ACACB,SLC2A4,PRKAG2,AKT1,NFKBIE,CAMKK1,NFKBIA,PPARA,ADIPOR1,PRKCQ,ACSL4,LEPR,SOCS3 |
| 7.855e-03 | -4.85 | Adipocytokine signaling pathway | KEGG pathways | ko04920 | 70 | 15 | 6908 | 758 |
PRKAA2,IRS2,ACACB,SLC2A4,PRKAG2,AKT1,NFKBIE,CAMKK1,NFKBIA,PPARA,ADIPOR1,PRKCQ,ACSL4,LEPR,SOCS3 |
| 7.857e-03 | -4.85 | mesonephric epithelium development | biological process | GO:0072163 | 89 | 17 | 16441 | 1675 |
HES1,FMN1,RET,SOX9,SDC4,SDC1,EPCAM,CTNNBIP1,FAT4,FGFR2,NPNT,BMP7,DLG1,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 7.857e-03 | -4.85 | mesonephric tubule development | biological process | GO:0072164 | 89 | 17 | 16441 | 1675 |
HES1,FMN1,RET,SOX9,SDC4,SDC1,EPCAM,CTNNBIP1,FAT4,FGFR2,NPNT,BMP7,DLG1,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 7.857e-03 | -4.85 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 89 | 17 | 16441 | 1675 |
PLK1,DLGAP5,AKT1,DNAJB2,GCLC,NUB1,PRICKLE1,PSMD10,TRIB2,RNF19B,BCAP31,PTEN,PLK2,AURKA,DAB2IP,ESPL1,SOCS5 |
| 7.861e-03 | -4.85 | Resolution of Sister Chromatid Cohesion | REACTOME pathways | R-HSA-2500257 | 100 | 19 | 8202 | 867 |
PLK1,ZWINT,CENPA,SPC25,CENPI,CDC20,NDC80,CDCA8,NUF2,CCNB1,CENPN,CDK1,PPP2R5A,CDCA5,BUB1,CENPE,NDE1,CCNB2,NUP85 |
| 7.875e-03 | -4.84 | centrosome | cellular component | GO:0005813 | 474 | 64 | 17570 | 1756 |
DYNLRB1,SORBS1,CEP70,DLGAP5,ACTR8,NDRG2,BCL2L1,SYTL4,CCNB1,PRKACA,STIL,CALM2,LRRC45,CNTRL,CEP78,PLK4,TUBG1,HYLS1,RP2,PDE4D,SNX10,CCDC38,PLK1,PCGF5,CAMSAP3,CCSAP,CDC20,KIF13A,PRKAR2B,CCNF,CDK1,NIN,CEP162,DZIP1L,STK26,PLK2,TRAF3IP1,RGS14,TRAF5,TTC8,CKAP2,POC1B,KIF23,CALM3,CCDC92,TOP2A,TFAP2A,NEK2,MPHOSPH9,CALM1,RGCC,NUBP1,DCTN6,MAPKAPK2,AURKA,PPP2R3C,MDH1,CEP41,CFAP20,WDR62,NDE1,CCNB2,ESPL1,DIS3L |
| 7.887e-03 | -4.84 | positive regulation of ion transport | biological process | GO:0043270 | 226 | 35 | 16441 | 1675 |
PRSS8,SCN5A,TCAF1,PINK1,LGALS3,ATP8A1,CALM3,PKP2,PDGFB,KIF5B,CALM2,ADORA1,STIM1,DPYSL2,PLCG2,SGK3,BAX,DLG1,SGK1,TRPC1,CACNA1D,F2R,CHP1,RAB3B,AKT1,CALM1,ANO6,ATP1B1,PLCG1,WFS1,STK39,FHL1,ATP1B3,GPER1,JAK3 |
| 7.899e-03 | -4.84 | MODULE_252 | MSigDB lists | MODULE_252 | 232 | 35 | 17758 | 1761 |
CCNE2,FOXM1,SOX9,PTTG1,NDC80,KIF23,PSMD10,CCNB1,BARD1,PHLDA1,RAD23A,TOP2A,CDKN2C,APLP2,WEE1,HSF2,NEK2,GTF2F2,BUB1,PLK1,ZWINT,CENPA,AKT1,UBE2A,MYBL2,FOS,PSMA4,CDK1,PRIM1,MAP2,DCK,STK38,HDAC1,CENPE,CCNB2 |
| 7.918e-03 | -4.84 | oligodendroglioma_Grade_III | COSMIC cancer mutations | oligodendroglioma_Grade_III | 316 | 45 | 17775 | 1757 |
EXPH5,GLIS3,ILDR1,PARP12,ARHGEF11,RET,TP53,ERBB2,PLXNA1,SBF1,NEO1,CDKN2C,MUC16,PTEN,OSBPL3,AIM1,PIK3CA,PCYOX1,CACNA1D,PANX2,PHKA2,TIAM1,MYT1,NEB,RIMS2,FARP2,MYO5B,AKT1,PIK3R1,PDE5A,HEATR5A,IDH1,GNA11,MAP3K6,GNAS,HS6ST1,PLEKHG6,JAK1,SHROOM3,SLC9A6,TANC2,FZD5,UNC5B,ABCA1,PCSK5 |
| 7.924e-03 | -4.84 | Integrated Pancreatic Cancer Pathway | WikiPathways | WP2377 | 194 | 34 | 4455 | 516 |
PRKAA2,PLA2G4A,CASP3,LTBP1,CD82,PTTG1,TP53,ERBB2,TGFBR1,TOP2A,PDGFA,CCND1,PTEN,CST3,PIK3CA,BAX,CDKN1B,MYT1,PLK1,SIRT1,AKT1,CASP9,GTF2A2,DAG1,RHEB,FAS,PITX2,AGPAT2,RBL1,NFKBIA,ABCB1,CAB39,MAP3K5,CAPN1 |
| 7.924e-03 | -4.84 | regulation of hemostasis | biological process | GO:1900046 | 82 | 16 | 16441 | 1675 |
ENPP4,SERPINE2,PLAUR,UBASH3B,ANO6,PRKCQ,TEC,F12,PDGFB,PDGFA,HPSE,FAM46A,PRKG1,F2RL1,F2R,SYK |
| 7.924e-03 | -4.84 | regulation of blood coagulation | biological process | GO:0030193 | 82 | 16 | 16441 | 1675 |
ENPP4,SERPINE2,PLAUR,UBASH3B,ANO6,PRKCQ,TEC,F12,PDGFB,PDGFA,HPSE,FAM46A,PRKG1,F2RL1,F2R,SYK |
| 7.950e-03 | -4.83 | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | 504 | 67 | 17758 | 1761 |
ILDR1,CCDC109B,GRHL2,NLRX1,PPM1J,ST14,HEBP1,FLYWCH2,DDIT4L,NDRG2,IL27RA,F11R,EPS8L2,NOV,AP1M2,CTGF,ARTN,PAQR5,PAPL,CLDN4,TACSTD2,TMEM37,SCARA3,SP5,GCA,SSH3,SLC39A8,HSPA12A,HTATIP2,CMTM7,PLEKHG6,BFSP1,C19orf66,SHROOM3,FAM110C,DHTKD1,PRKCDBP,F2RL1,PRR15,LGALS3,IGFBP6,CTSZ,ISYNA1,ANO1,IL17RB,CXCL16,SGK3,C10orf54,FAR2,GCNT1,FAH,DLGAP1,RAB3B,SYBU,GYLTL1B,PCTP,CRISPLD2,CD83,PRKAG2,TMEM54,ABCB1,NR4A3,CDK18,MAL2,RARG,ARHGEF4,PROM2 |
| 7.951e-03 | -4.83 | KINESIN_MOTOR_1 | prosite domains | PS00411 | 41 | 10 | 11866 | 1235 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 7.963e-03 | -4.83 | AGGGCCA,MIR-328 | MSigDB lists | AGGGCCA,MIR-328 | 77 | 15 | 17758 | 1761 |
LGR4,NR3C1,CSNK1G1,PTPN9,ARL4C,ZNF704,TESK2,FAM133B,PIM1,TTYH3,SIX4,NRP2,PRX,FGD1,DPYSL3 |
| 7.963e-03 | -4.83 | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | MSigDB lists | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | 77 | 15 | 17758 | 1761 |
LMO7,RASSF8,NOV,CA2,FAM46A,CPEB4,CYB5R2,MRS2,LRIF1,FAM46C,IFI6,ESPL1,PTGES,SYTL2,SOCS3 |
| 7.966e-03 | -4.83 | - | gene3d domains | 1.10.418.10 | 71 | 15 | 9988 | 1080 |
GAS2L1,LMO7,SMTNL2,ASPM,IQGAP1,SYNE2,UTRN,CLMN,SPTBN5,DIXDC1,LIMCH1,TAGLN2,IQGAP3,SPTB,PLS3 |
| 7.975e-03 | -4.83 | frontotemporal | COSMIC cancer mutations | frontotemporal | 9 | 4 | 17775 | 1757 |
CDKN2C,IDH1,PTEN,TP53 |
| 7.975e-03 | -4.83 | chondroma | COSMIC cancer mutations | chondroma | 9 | 4 | 17775 | 1757 |
GNAS,ERBB2,IDH1,TP53 |
| 7.991e-03 | -4.83 | protein serine/threonine/tyrosine kinase activity | molecular function | GO:0004712 | 42 | 10 | 16491 | 1673 |
PRKAA2,RPS6KA2,AKT1,TESK1,RPS6KA1,MAP3K9,TESK2,AURKA,SGK1,PRKACA |
| 8.001e-03 | -4.83 | positive regulation of cellular protein catabolic process | biological process | GO:1903364 | 179 | 29 | 16441 | 1675 |
PLK1,DLGAP5,PSMB4,AKT1,DNAJB2,GCLC,PSME2,CDC20,NUB1,PRICKLE1,PSMD10,EZR,PSME1,TRIB2,CCNB1,RNF19B,PSMA4,CDK1,BCAP31,PSMD1,RNF128,CTSC,PTEN,PLK2,AURKA,DAB2IP,UBE2C,ESPL1,SOCS5 |
| 8.004e-03 | -4.83 | MODULE_291 | MSigDB lists | MODULE_291 | 63 | 13 | 17758 | 1761 |
MYL9,FOXM1,TRIP10,SEMA4D,SECTM1,NRG1,GDF15,PIEZO1,ATP1B1,LGMN,ETS1,LGALS3BP,IER3 |
| 8.008e-03 | -4.83 | central_nervous_system-brain-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_III | 1482 | 174 | 17775 | 1757 |
LTBP1,KLK10,SLC25A13,TMEM41B,HEXB,RET,ARFGEF1,NRG2,LYNX1,SYTL4,PLXNA1,DNER,SLC9A7,CDKN2C,HSF2,MUC4,LRRC6,STIM1,ARHGEF37,IQCE,OSBPL3,CYP2S1,TSPAN6,SLC44A1,AOX1,PIK3CA,ATRNL1,IRF2,NTN4,TLN2,MYRIP,NEB,MCTP1,NBPF3,MTRF1L,CR2,LDB2,IDH1,ADRBK2,COL12A1,MAN2A2,ANKRD10,PLK2,ATP7B,NFKBIZ,PIEZO1,RELL1,TANC2,CPPED1,FRMD4A,TBC1D1,PYROXD2,MTL5,CNTNAP2,SAMD9,TNS3,RALGPS2,IGF1R,PRKG1,MAP3K9,CADPS2,CACNA1D,LRIF1,SLC12A2,TRAK2,GFPT1,CHSY3,HPS3,MFI2,TBC1D8B,MICB,GNA11,SOX13,GNAS,BCAR3,XKRX,CACHD1,AP1AR,PVRL2,PRPS2,ITPR1,PITPNA,DRP2,MAP3K5,SHROOM2,SEMA3A,XDH,DOCK9,PLA2G4A,CCNE2,NCKAP5,SPRED1,NF2,REPS2,IL15,IQGAP1,TP53,ERBB2,GRK6,CYP39A1,ZFYVE9,ZNF385B,CDS1,RAD23A,MUC16,SP100,FRYL,CDKN1B,RTKN2,NR2C1,SCN3A,TMTC1,SEC23A,ZNF525,AKT1,PTPRU,UTRN,ASB13,DOCK5,FZD7,CMTM7,PTPRJ,IDE,ATP1A1,SHROOM3,CDK19,SLC27A1,EFNA5,SYT13,NR3C2,COBL,NDST3,DENND5B,CDH22,BLVRB,OSGIN2,HERC5,TGFBR1,DSE,FAM167A,PARM1,SLC9A2,MDM1,ADRBK1,SLC27A6,ANKS1B,PTEN,MGAT4A,GTF2F2,ERBB3,IQGAP3,GCNT1,RASGRF1,PDGFC,FAM160A1,ASPM,RC3H2,PIK3R1,PPARA,MBNL3,DIAPH2,MAML2,SNTB1,CD83,GPLD1,DCTN6,FAT4,ABCB1,PPM1H,CLIP4,GRIN2D,TBC1D4,ARSB,TLL2 |
| 8.019e-03 | -4.83 | EPHA2 (EPH receptor A2) | protein interactions | 1969 | 52 | 12 | 16036 | 1726 |
PIFO,CDK17,ITGA3,ADRBK1,RBL1,PSME2,PIK3R1,CLDN4,EFNA5,ITGAV,TIAM1,RASA1 |
| 8.022e-03 | -4.83 | integrin binding | molecular function | GO:0005178 | 104 | 19 | 16491 | 1673 |
TIMP2,FBLN5,NF2,ITGA6,UTRN,ERBB2IP,FBLN1,EMP2,NOV,ITGA3,CTGF,CYR61,NPNT,PLPP3,CD9,ADAM15,SYK,COL16A1,L1CAM |
| 8.039e-03 | -4.82 | KEGG_PANCREATIC_CANCER | MSigDB lists | KEGG_PANCREATIC_CANCER | 70 | 14 | 17758 | 1761 |
PGF,CCND1,JAK1,AKT1,RALBP1,CASP9,PIK3R1,PIK3CA,TP53,ERBB2,TGFBR1,PIK3CD,BCL2L1,PLD1 |
| 8.039e-03 | -4.82 | PID_CDC42_PATHWAY | MSigDB lists | PID_CDC42_PATHWAY | 70 | 14 | 17758 | 1761 |
RASGRF1,CDH1,IQGAP1,LIMK1,EPS8,PIK3R1,DLG1,PIK3CA,PLD1,YES1,IQGAP3,ARPC2,BCAR1,TIAM1 |
| 8.043e-03 | -4.82 | GGGNNTTTCC_V$NFKB_Q6_01 | MSigDB lists | GGGNNTTTCC_V$NFKB_Q6_01 | 129 | 22 | 17758 | 1761 |
LASP1,CPEB4,TNIP1,HSPG2,TP53,PKN1,BMP2K,SH3KBP1,CNTNAP1,RAP2C,NFKBIA,SLC44A1,KCNS3,FAM117A,CD70,SP6,GEM,JAK3,SLC12A2,NRGN,PTGES,EHD1 |
| 8.052e-03 | -4.82 | TTTTGAG,MIR-373 | MSigDB lists | TTTTGAG,MIR-373 | 216 | 33 | 17758 | 1761 |
FRMD4A,NF2,KLHL13,ZCCHC24,SOX9,ARFGEF1,C6orf106,KCTD12,MPP5,PSIP1,VPS26A,WDR44,IMPAD1,EPB41L4B,C9orf72,KDELR1,PHF20L1,FBLN5,MBP,C2orf69,PDIK1L,DAG1,ADRBK2,ARF4,SLC4A4,FGFR2,SETD3,PTER,AMMECR1,HDAC1,KLF5,NDFIP1,TOB1 |
| 8.067e-03 | -4.82 | Metal-dep_hydrolase_composite | interpro domains | IPR011059 | 9 | 4 | 18293 | 1814 |
DPYSL5,AMDHD1,DPYSL2,DPYSL3 |
| 8.067e-03 | -4.82 | PDGF/VEGF_dom | interpro domains | IPR000072 | 9 | 4 | 18293 | 1814 |
PGF,PDGFA,PDGFC,PDGFB |
| 8.067e-03 | -4.82 | FOCAL_ADHESION_FORMATION | MSigDB lists | FOCAL_ADHESION_FORMATION | 9 | 4 | 17758 | 1761 |
TESK2,SORBS1,PTEN,ACVRL1 |
| 8.067e-03 | -4.82 | BENPORATH_ES_CORE_NINE | MSigDB lists | BENPORATH_ES_CORE_NINE | 9 | 4 | 17758 | 1761 |
NFE2L3,KLF5,HMGA1,MYBL2 |
| 8.067e-03 | -4.82 | ST_JAK_STAT_PATHWAY | MSigDB lists | ST_JAK_STAT_PATHWAY | 9 | 4 | 17758 | 1761 |
PIAS3,JAK1,PTPRU,JAK3 |
| 8.067e-03 | -4.82 | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | MSigDB lists | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | 9 | 4 | 17758 | 1761 |
GDF15,SESN1,TP53I3,SULF2 |
| 8.068e-03 | -4.82 | THIOREDOXIN_2 | prosite domains | PS51352 | 35 | 9 | 11866 | 1235 |
DNAJC10,TXN,TMX4,PDIA5,PDIA3,PDIA6,TXNDC11,PDIA4,PRDX4 |
| 8.091e-03 | -4.82 | KINESINHEAVY | prints domains | PR00380 | 44 | 10 | 4759 | 462 |
KIF5B,KIF20A,KIFC2,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 8.098e-03 | -4.82 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 168 | 27 | 17758 | 1761 |
EXPH5,NUDT6,FAM169A,HABP4,ABCG2,ITPR2,PHLPP1,TRIB2,MERTK,TNFRSF19,ADRBK2,ZNF385B,FAS,HLF,CYP1A1,SLC4A4,RAB11FIP2,KCNK1,NKD1,ANKFN1,RUNDC3B,AOX1,TMEM64,SLC25A30,MYRIP,ALDH3A2,CPPED1 |
| 8.108e-03 | -4.81 | V$LEF1_Q2 | MSigDB lists | V$LEF1_Q2 | 208 | 32 | 17758 | 1761 |
PLA2G4A,SORBS1,RET,FGF19,ZFYVE9,RCN1,AIM1L,ADD3,ADRBK1,RALGPS2,PHTF1,ELF5,FAM63A,DUSP10,TACSTD2,IQGAP3,TMEM9,PVRL4,PCGF5,PANK1,RUNX3,ASB13,RNF19B,CDK1,PTPRJ,UAP1,COL13A1,OVOL1,EIF4EBP2,SYT13,LEMD1,TLL2 |
| 8.127e-03 | -4.81 | VANHARANTA_UTERINE_FIBROID_UP | MSigDB lists | VANHARANTA_UTERINE_FIBROID_UP | 43 | 10 | 17758 | 1761 |
CCND1,DDB2,TFAP2C,TGOLN2,LOXL2,LTBP2,SPCS3,ZFYVE9,EDNRA,IGSF3 |
| 8.127e-03 | -4.81 | KEGG_GLYCEROLIPID_METABOLISM | MSigDB lists | KEGG_GLYCEROLIPID_METABOLISM | 43 | 10 | 17758 | 1761 |
DGKH,ALDH2,AGPAT2,DGKQ,AKR1B1,ALDH7A1,GLA,DGKG,ALDH3A2,DGKE |
| 8.127e-03 | -4.81 | ZHAN_MULTIPLE_MYELOMA_CD1_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_DN | 43 | 10 | 17758 | 1761 |
HES1,TNS3,RAB3B,CPEB4,BHLHE41,FUT8,F11R,BCL2L1,ITPR3,CMTM4 |
| 8.127e-03 | -4.81 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | 43 | 10 | 17758 | 1761 |
ELK3,RUNX2,CTGF,REEP1,GEM,DUSP4,RASGEF1A,MAP3K5,PHLDA1,MAFF |
| 8.127e-03 | -4.81 | ZHAN_MULTIPLE_MYELOMA_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD2_UP | 43 | 10 | 17758 | 1761 |
B3GALNT1,TGIF1,APLP2,SORT1,PTPRJ,PIK3AP1,PHLPP2,PRDM5,DHTKD1,TRAF5 |
| 8.128e-03 | -4.81 | Kinesin-like_fam | interpro domains | IPR027640 | 43 | 10 | 18293 | 1814 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 8.131e-03 | -4.81 | Downregulation of ERBB2:ERBB3 signaling | REACTOME pathways | R-HSA-1358803 | 13 | 5 | 8202 | 867 |
ERBB2,NRG2,NRG1,ERBB3,AKT1 |
| 8.131e-03 | -4.81 | Uptake and function of anthrax toxins | REACTOME pathways | R-HSA-5210891 | 13 | 5 | 8202 | 867 |
CALM3,CALM2,ANTXR1,CALM1,FURIN |
| 8.143e-03 | -4.81 | MODULE_177 | MSigDB lists | MODULE_177 | 99 | 18 | 17758 | 1761 |
NR3C1,MPP1,CDC20,ARHGDIB,IFIT3,LBR,CD83,TOP2A,JAK1,DDOST,NMI,NFKBIA,RANBP1,PLCG2,SORL1,SGK1,ST3GAL1,TRAM1 |
| 8.145e-03 | -4.81 | response to oxygen levels | biological process | GO:0070482 | 291 | 43 | 16441 | 1675 |
CASP3,PINK1,NKX3-1,SLC2A4,CPEB4,EPAS1,TP53,SELL,ITPR2,CCNB1,PDGFB,ETS1,LMNA,CYP1A1,ADORA1,CTGF,PTEN,BMP7,VASN,CST3,CDKN1B,AHCY,TWIST1,CITED2,EGLN3,SIRT1,RHOA,AKT1,RGCC,PPARA,PRKCQ,SLC11A2,LOXL2,PDK3,ATP1B1,FAS,EDNRA,SOCS3,PLOD2,ITPR1,NR4A2,CPEB2,EGLN1 |
| 8.147e-03 | -4.81 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | 176 | 28 | 17758 | 1761 |
ZNF462,SPRED1,TRIM2,RAPGEF2,CYB5R2,SOX9,NDRG2,FOS,ATP10D,NFIB,FZD7,ELF3,PLEKHH2,SERPINA1,ITGB8,PDLIM3,RND3,MAP2,HOXA9,BHLHE41,ALDH1A3,FOSB,ELF5,FAM110C,CDH3,KLK7,MAFF,SOCS5 |
| 8.148e-03 | -4.81 | V$TCF11MAFG_01 | MSigDB lists | V$TCF11MAFG_01 | 200 | 31 | 17758 | 1761 |
UNKL,RASGRF1,SPRED1,MRC2,LRRFIP2,ARHGEF11,BLVRB,CALM1,CBX6,CALM3,IL13RA1,GRK6,ATP1B1,PDGFB,SFXN5,SNX12,BEX2,VPS26A,PLS3,CALM2,ST5,POPDC3,WDR44,LIMK1,LMO4,MITF,PGRMC1,DRP2,NRGN,RIMS2,JARID2 |
| 8.169e-03 | -4.81 | Signaling events mediated by VEGFR1 and VEGFR2 | Pathway Interaction DB | vegfr1_2_pathway | 63 | 17 | 2227 | 331 |
RHOA,AKT1,EPAS1,IQGAP1,PIK3R1,CALM1,CALM3,YES1,PRKACA,NRP2,CALM2,PLCG1,PIK3CA,MAPK11,ITGAV,HSPB1,GAB1 |
| 8.169e-03 | -4.81 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | 192 | 30 | 17758 | 1761 |
LZTFL1,TXN,FAM92A1,TTC39B,IL15RA,LGALS3,BVES,SLC39A8,FLYWCH2,S100A4,SAT1,CDA,NDUFA4,CASP4,FRMD4B,EPDR1,SOCS3,SNTA1,CSF1,BMP7,RYK,ABCB1,OTUB2,ECI2,PPP2R3C,MDFIC,CTTN,TMEM159,F2R,ABCG1 |
| 8.169e-03 | -4.81 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 30 | 17758 | 1761 |
EXPH5,SUN2,DDB2,SEC61B,SERPINE2,S100A11,HAL,COL4A5,CRABP2,MERTK,ABR,RHEB,PDIA4,PRIM1,SLC6A6,RPL12,PPP2R5A,STIM1,PRCP,NR4A3,MANF,PIM1,TLN2,LTA4H,TRAF5,TRAM1,TIAM1,GAB1,CBX7,LAMP3 |
| 8.169e-03 | -4.81 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_UP | 192 | 30 | 17758 | 1761 |
CCNI,ANXA3,PGM1,SPC25,SLC37A1,KIF20A,CPT2,GNE,CDC20,KIF1C,HTATIP2,COL4A5,FAM198B,PDK3,CYP4F3,ANKRD10,SLC25A4,WIPI1,PEX2,ABCA2,FAM63A,TMEM51,ARRB1,BUB1,ABCD1,CTSA,PLD1,PHKA2,MYL12B,CPPED1 |
| 8.169e-03 | -4.81 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | 192 | 30 | 17758 | 1761 |
MRPS33,PSMB4,IL15,IFITM3,SH3BGRL,SLC25A13,CDCA2,LYNX1,NPC2,HERC6,KBTBD11,RNF19B,PSMA4,PRDX4,TAPBP,NOV,ELMO2,RBL1,OSBPL3,PEX2,NMI,NEK2,GTF2F2,MRPS28,ECE1,LMAN1,TIAM1,E2F8,SLC16A5,KDELR1 |
| 8.169e-03 | -4.81 | GSE17721_CTRL_VS_LPS_6H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDM_DN | 192 | 30 | 17758 | 1761 |
PPIF,GCA,TTC39B,PLSCR1,SLC39A8,MPP1,RUSC2,RASA2,NUB1,FURIN,IL18,F11R,KREMEN1,SPTB,CMTM6,PSMA4,REPS1,ARF4,IER3,PTPRJ,ARTN,ACADSB,RND3,LLGL2,WFS1,RANBP1,CST3,SNX16,AHR,PTGES |
| 8.169e-03 | -4.81 | GSE17721_CTRL_VS_POLYIC_24H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDM_DN | 192 | 30 | 17758 | 1761 |
UGP2,RIPK2,GCLC,CD82,NUB1,GDF15,ARFRP1,PDK3,SPTLC2,PSMA4,KIAA1161,ARF4,ABR,CD83,RAD23A,RBM47,CDH1,GDE1,BHLHE41,IL6ST,LMO4,MMP17,NFKBIA,RANBP1,CST3,MDFIC,TSPAN13,PLIN3,PTGES,TMEM131 |
| 8.169e-03 | -4.81 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | 192 | 30 | 17758 | 1761 |
NF2,ST14,TBC1D1,XYLT1,FURIN,PPFIBP2,IL27RA,BLVRA,ICMT,SPR,H2AFV,GSTP1,RANBP9,MAPK8IP1,SLC25A36,BCAR3,TFAP4,HLF,TIMP3,CTSC,GDE1,PRCP,PNPLA6,TACSTD2,PLCB2,SPRY2,ATP2B1,LAMP3,PCSK5,ABCG1 |
| 8.169e-03 | -4.81 | GSE17721_PAM3CSK4_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_2H_BMDM_UP | 192 | 30 | 17758 | 1761 |
PVRL4,BCAM,PSMB4,NF2,KLHL13,DNAJC3,GNE,PARP4,PRSS22,LPIN3,TRIB2,KCTD2,SESN1,COL12A1,NUDT16,RALGPS2,CORO1C,N4BP3,SLC44A1,ALDH1A3,POF1B,PLEKHF1,TNFRSF12A,MARCH2,LRRK1,C1orf43,PDIA6,CDKN2D,TPCN1,MPHOSPH9 |
| 8.169e-03 | -4.81 | GSE17721_LPS_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_8H_BMDM_UP | 192 | 30 | 17758 | 1761 |
GRN,ENPP4,PMPCB,RUNX2,STAT4,SAT1,PLEKHO1,SERTAD3,HMGN3,FAM198B,SPTLC2,RNF19B,PSMA4,LGALS3BP,HLA-B,DOPEY2,PLEKHG6,SWAP70,CSF1,ZFP36,RAP2C,SLC44A2,CDKN1B,ECE1,GLA,MINPP1,PLOD3,RGS14,ST3GAL1,SNX10 |
| 8.169e-03 | -4.81 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | 192 | 30 | 17758 | 1761 |
LMO7,TIMP2,CD82,PLEKHO1,ARL4C,CYB561,TRIB2,CA8,FBLN1,PHLDA1,DENND2D,CYB5A,IGF1R,MMP17,P4HA2,RYK,FGD6,ARVCF,SH3BGRL2,RAB20,STK39,HOXB13,CTTN,ITGAV,GEM,LGMN,SCARA3,TRAF5,TLE6,PKIA |
| 8.169e-03 | -4.81 | GSE17721_0.5H_VS_24H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_LPS_BMDM_UP | 192 | 30 | 17758 | 1761 |
ANXA3,SHMT1,FBLN5,GUSB,ASPM,LPGAT1,CDC20,KIF1C,KLK6,FAM198B,TRIB2,SEPP1,FOXL1,DAG1,STEAP1,LEPR,H1FX,CDKN2C,SCNN1A,TIMM8A,RND3,PPP4R1,AKR1B1,ARRB1,KLF5,MRPS28,GLCCI1,AHR,JARID2,TMEM131 |
| 8.170e-03 | -4.81 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | 184 | 29 | 17758 | 1761 |
BIN1,ARHGEF3,MBP,UGT8,CHCHD7,CAST,STAT4,FXYD3,SELL,MTRF1L,CYB561,FAM198B,SESN1,SRPX2,LGALS3BP,TMEM63A,EPCAM,HLA-B,ADD3,HSF2,TRANK1,IL6ST,KBTBD2,ZDHHC7,WWP1,IRF7,ALPK1,ECE1,S100A13 |
| 8.176e-03 | -4.81 | Ubiquitin-rel_dom | interpro domains | IPR029071 | 184 | 29 | 18293 | 1814 |
FRMPD3,EPB41L5,ARAP3,FRMD4A,NF2,FRMD6,RAPGEF2,DGKQ,NUB1,RASSF7,EZR,FRMD4B,RAD23A,GABARAPL1,RASSF8,ZFAND4,PIK3CA,DIXDC1,YOD1,PIK3C2B,EPB41L4B,PIK3CD,TECR,RGS14,TLN2,EPB41L4A,MYLIP,DVL2,FARP2 |
| 8.192e-03 | -4.80 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 114 | 20 | 17758 | 1761 |
CASP3,TIMP2,IGFBP6,PLAUR,LITAF,TP53,ERBB2,GSTP1,FAS,BTG3,WEE1,TIMP3,PTEN,SHC3,IL6ST,BAX,DAPK1,CDKN1B,IGFBP2,HSPB1 |
| 8.197e-03 | -4.80 | asymmetric protein localization | biological process | GO:0008105 | 24 | 7 | 16441 | 1675 |
SCRIB,MPP5,ERBB2IP,NCKAP1,SHROOM2,SHROOM3,ARF4 |
| 8.197e-03 | -4.80 | negative regulation of viral transcription | biological process | GO:0032897 | 24 | 7 | 16441 | 1675 |
TFAP4,TRIM21,HDAC1,TRIM8,SP100,IFITM3,TRIM62 |
| 8.197e-03 | -4.80 | establishment of mitotic spindle localization | biological process | GO:0040001 | 24 | 7 | 16441 | 1675 |
NUSAP1,CENPA,GPSM2,NDE1,SPRY2,ESPL1,NDC80 |
| 8.209e-03 | -4.80 | synovial_sarcoma | COSMIC cancer mutations | synovial_sarcoma | 92 | 17 | 17775 | 1757 |
SGCE,LCA5,AKT1,NR3C1,TP53,ERBB2,IDH1,TXNDC11,PRX,SS18,DNAJC10,CDH1,PTEN,CDK19,PIK3CA,SORL1,TRAF5 |
| 8.214e-03 | -4.80 | DERL2 (derlin 2) | protein interactions | 51009 | 34 | 9 | 16036 | 1726 |
ERLEC1,MFI2,SERPINA1,AMFR,UBE2J1,EMC2,SARAF,RPN2,POR |
| 8.214e-03 | -4.80 | NKX3-1 (NK3 homeobox 1) | protein interactions | 4824 | 34 | 9 | 16036 | 1726 |
LMCD1,HMG20B,HDAC1,STMN3,RARG,CKAP4,SP5,SP4,CHPF |
| 8.214e-03 | -4.80 | PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma) | protein interactions | 5294 | 34 | 9 | 16036 | 1726 |
PRKAA2,ADRBK1,IL6ST,UTRN,PDE4D,PIK3CD,GAB1,SYK,GABARAPL1 |
| 8.214e-03 | -4.80 | GMPS (guanine monophosphate synthase) | protein interactions | 8833 | 34 | 9 | 16036 | 1726 |
RCN1,PRKAG2,ENO2,AGPAT2,EFHD2,AHCY,GLO1,FBXO6,HSPB1 |
| 8.214e-03 | -4.80 | LIMK2 (LIM domain kinase 2) | protein interactions | 3985 | 34 | 9 | 16036 | 1726 |
RCN1,MBP,ATP1A1,SSH1,LIMK1,SLC25A13,HSPB1,HIPK3,LMNA |
| 8.216e-03 | -4.80 | regulation of MAP kinase activity | biological process | GO:0043405 | 283 | 42 | 16441 | 1675 |
SPRED1,AVPI1,EPHA4,ERBB2,PKN1,TRIB2,PDGFB,GSTP1,ERP29,PDGFA,BMP7,RGS3,MAP3K9,DUSP10,SORL1,DAB2IP,MAPK11,MDFIC,IQGAP3,SYK,SPRY2,DVL2,RASGRP1,MDFI,RIPK2,FZD4,PDE5A,DUSP4,CD40,CDK1,MAP3K6,MAPKAPK2,PTPRJ,STK38,MADD,NOD2,ARRB1,FZD5,RGS14,MAP3K5,GAB1,HIPK3 |
| 8.217e-03 | -4.80 | PID_EPHA2_FWD_PATHWAY | MSigDB lists | PID_EPHA2_FWD_PATHWAY | 19 | 6 | 17758 | 1761 |
RHOA,BCAR1,TIAM1,PIK3R1,ARHGAP35,PIK3CA |
| 8.217e-03 | -4.80 | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | MSigDB lists | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | 19 | 6 | 17758 | 1761 |
F11R,PIM1,UNC5B,PVRL2,PDGFB,LEPR |
| 8.217e-03 | -4.80 | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | 19 | 6 | 17758 | 1761 |
GABRG2,MYL9,LOC81691,SORBS1,RIMS2,RAB23 |
| 8.217e-03 | -4.80 | MODULE_320 | MSigDB lists | MODULE_320 | 19 | 6 | 17758 | 1761 |
KIF23,CENPE,KIF11,ESPL1,PTTG1,NDC80 |
| 8.217e-03 | -4.80 | RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 19 | 6 | 17758 | 1761 |
ARHGEF3,ARHGEF11,TIAM1,RAPGEF2,MADD,FARP2 |
| 8.217e-03 | -4.80 | GRANDVAUX_IRF3_TARGETS_DN | MSigDB lists | GRANDVAUX_IRF3_TARGETS_DN | 19 | 6 | 17758 | 1761 |
SORL1,TIMP3,GEM,STK17B,RASA1,PPP2R3A |
| 8.217e-03 | -4.80 | TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP | MSigDB lists | TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP | 19 | 6 | 17758 | 1761 |
LAMP2,B3GALNT1,CDH1,GLCCI1,RAB11FIP1,CKS2 |
| 8.217e-03 | -4.80 | INSULIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | INSULIN_RECEPTOR_SIGNALING_PATHWAY | 19 | 6 | 17758 | 1761 |
SORBS1,IGF1R,AKT1,BCAR1,GAB1,PIK3R1 |
| 8.217e-03 | -4.80 | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP | 19 | 6 | 17758 | 1761 |
WEE1,GATA2,NGFRAP1,COL16A1,CST3,FAH |
| 8.217e-03 | -4.80 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | MSigDB lists | REACTOME_ENOS_ACTIVATION_AND_REGULATION | 19 | 6 | 17758 | 1761 |
CALM2,CALM3,AKT1,SPR,CALM1,ZDHHC21 |
| 8.217e-03 | -4.80 | chr7p12 | MSigDB lists | chr7p12 | 19 | 6 | 17758 | 1761 |
SUN3,TNS3,FIGNL1,SEMA3A,COBL,STK17A |
| 8.227e-03 | -4.80 | negative regulation of leukocyte mediated immunity | biological process | GO:0002704 | 42 | 10 | 16441 | 1675 |
HLA-B,HLA-E,BCL6,NOD2,TAP1,C10orf54,NDFIP1,JAK3,ABR,HLA-A |
| 8.228e-03 | -4.80 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2863 | 319 | 17775 | 1757 |
HECA,ACACB,GAA,PPP4R4,TSC22D3,TAP1,NRG2,CCNB1,DPP8,FAM46C,CDKN2C,DAPK2,CTGF,KIAA1107,STIM1,IQCE,CABP1,PAQR5,IL31RA,AOX1,STEAP2,PIK3CA,ATRNL1,MTMR11,TMEM37,TIAM1,XKR8,SPEF2,HSPA12A,TNS1,LDB2,SPNS3,ABR,ARHGEF26,AHRR,ANKRD6,ATP7B,LRIG1,FAM114A1,NOD2,PRDM5,RELL1,GAB1,DDX58,SCN5A,MRC2,FRMD4A,CDKN1C,TBC1D1,CALB2,MTL5,SLC1A3,MERTK,RAVER2,DOPEY2,RALGPS2,ITGA3,FAM189A1,MEGF8,PRKG1,SORL1,CADPS2,CACNA1D,RIMS2,MCCC2,TRAK2,PRODH,KCNJ12,KLK5,LPGAT1,MYBL2,ATP8B3,NPHP3,SFXN5,NFIB,DCP2,FAS,CACHD1,AP1AR,PLEKHH2,FAAH,ISM1,TCEAL4,NDE1,MAP3K5,DOCK9,MFSD3,S100A11,IQGAP1,RALBP1,RNF182,MGST2,DDR1,ZNF385B,CDS1,CCND1,MUC16,SCNN1A,MYT1,SCN3A,MYO5B,MX1,SEC23A,FOXJ2,DRAP1,SYNE2,UTRN,DNAJB14,PYGO1,ATP10D,PRDM11,JAK1,PDLIM3,SHROOM3,WFS1,INPP4B,TRIOBP,ZNF704,NRG1,NR3C2,COBL,PDIA3,EFHD2,SEPP1,NEO1,SLC25A36,WWP2,SNTA1,FUT2,ANKS1B,CTSC,FAM20B,ATP8B1,WWP1,NCOA2,RASGRF1,PDGFC,PLSCR1,FAM160A1,FMN1,RAPGEF2,MFSD2B,PIK3R1,CXorf57,AK4,DIAPH2,YES1,GRTP1,ARSK,RPL12,MAMDC4,RAB11FIP2,ABCB1,ARSB,USF2,CXorf56,OCLN,TLL2,EXPH5,LTBP1,LMCD1,MPP5,VARS2,ITPR2,PDGFB,DNER,KREMEN1,TMC1,DENND2D,PLS3,NKAIN3,ARHGEF10L,SIPA1L2,ARHGEF37,SHC3,NPNT,IMPAD1,ANKFN1,SLC44A1,DLG1,DUSP10,RP2,MYH14,ANO4,MYRIP,BTBD3,RASGRP1,ZNF462,MCTP1,CELSR2,NFE2L1,RGAG1,ANLN,SESN1,PTGFRN,EDNRA,DPYSL3,MDK,MAN2A2,PLCH1,MFAP3L,NEIL1,GPRC5B,KLF12,MAP2,KLF11,EPB41L4A,GLCCI1,PRKAA2,LASP1,BVES,HLA-F,SAMD9,CNTNAP2,PHLPP1,IL18R1,ANO1,FRAS1,MDFIC,LIMCH1,PIM1,ALS2CL,MDFI,CHSY3,RGMB,PDE5A,HMG20B,EIF2AK1,ANKRD29,AMDHD1,SOX13,RASGRP2,UTP14C,ALPK3,CTSA,LTBP2,PLD1,SEMA3A,COL16A1,NIPA1,USP43,NCKAP5,NF2,FOXM1,TP53,TDRKH,OSR2,STIL,CYP4F11,FRYL,N4BP3,RPN2,EGLN3,F2R,MBP,ERBB2IP,DOCK5,TAPBP,BFSP1,PTK7,ADAMTS14,TLE1,EFNA5,SPTBN5,IRF7,CYP2U1,LIFR,NDST3,TSPAN15,POC1B,GABRG2,SELL,COL4A5,NRP2,PPP2R3A,CD109,FOXP2,IRF2BPL,MDM1,BMP7,GALNS,GTF2F2,ARVCF,ALDH7A1,CLIP2,TLE6,HMMR,DLGAP1,SUN2,FBLN5,RAB3B,AMFR,ASPM,RC3H2,MAML2,COL7A1,PELI3,TXNDC11,BBS2,PRDX4,ENDOD1,ARHGAP24,FAT4,SERPINA1,TMC5,CDCA7L,PGRMC1,FAM117A,UACA,ARRB1,CLIP4,SH3BGRL2,GRAMD1C,SOX8,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1 |
| 8.247e-03 | -4.80 | Metabolism of carbohydrates | REACTOME pathways | R-HSA-71387 | 274 | 42 | 8202 | 867 |
GAA,SLC35D2,SLC2A4,PAPSS2,ENO2,UGP2,HSPG2,SLC25A13,SDC4,HEXB,CALM3,DSE,B4GALT4,SDC1,PRKACA,CHPF,GNS,CALM2,PAPSS1,AKR1B1,GOT1,PHKA2,NUP85,CHP1,HMMR,B3GALT6,CHSY3,PGM1,B3GNT7,B3GNT2,GUSB,CALM1,GLCE,HS6ST1,HPSE,PRPS2,MDH1,HS3ST3B1,ARSB,ST3GAL1,NDST3,NUP58 |
| 8.270e-03 | -4.80 | KEGG_INSULIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_INSULIN_SIGNALING_PATHWAY | 137 | 23 | 17758 | 1761 |
PRKAA2,ACACB,SLC2A4,SORBS1,AKT1,TRIP10,INPP5D,CALM1,PIK3R1,CALM3,PRKAR2B,ELK1,PRKACA,RHEB,SOCS3,CALM2,PTPRF,IRS2,PRKAG2,SHC3,PIK3CA,PIK3CD,PHKA2 |
| 8.272e-03 | -4.79 | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | 5 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 8.272e-03 | -4.79 | breast-carcinoma-medullary_carcinoma | COSMIC cancer mutations | breast-carcinoma-medullary_carcinoma | 5 | 3 | 17775 | 1757 |
AKT1,PIK3CA,TP53 |
| 8.272e-03 | -4.79 | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | 5 | 3 | 17775 | 1757 |
NF2,IDH1,TP53 |
| 8.272e-03 | -4.79 | astroblastoma_Grade_III | COSMIC cancer mutations | astroblastoma_Grade_III | 5 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 8.286e-03 | -4.79 | ITGB5 (integrin beta 5) | protein interactions | 3693 | 46 | 11 | 16036 | 1726 |
SNTA1,LTBP1,KLK5,ITGA3,CYR61,EPS8,PDIA3,ATP1B3,ITGAV,MERTK,LTBP3 |
| 8.289e-03 | -4.79 | oesophagus-lower_third-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-adenocarcinoma | 6579 | 697 | 17775 | 1757 |
ACACB,AASS,SLC25A13,RET,CACNA2D2,DHX8,CA8,BARD1,LTBP3,GRM5,EPDR1,DAPK2,PSMD1,MUC4,ALDH1A3,KLF3,SEMA3G,TIAM1,TIPARP,MGAT5,ERAP2,NWD1,SMARCA2,TNIP1,SH3BGRL,CDA,MTRF1L,TMEM151A,PRKAR2B,LOXL2,PPP1R14C,COL12A1,PIAS3,ENPP1,DNM1L,ATP7B,FAM114A1,NOD2,AGFG2,ITPKA,NXT2,SCN5A,NFKBIE,FAM169A,SOX9,SLC36A4,MERTK,TTYH3,MARCH8,GNS,FRY,RIMS3,MEGF8,FLRT3,FAM13B,PCYOX1,CADPS2,ALPK1,PANX2,ZMYM1,NCAM1,MYLIP,DGKG,NUP85,HPS3,SLC37A1,KIF20A,SALL4,STAT4,NPHP3,PCTP,DCP2,DHX32,PTPRF,CACHD1,NCOA3,ETS2,ITPR1,AURKA,GDF11,TMEM159,NDE1,ARPC2,SERPINB1,XDH,ADAMTS16,EGLN1,DOCK9,NQO1,ACTR8,RGS20,TESK2,PKP2,PRSS22,NUF2,PRKACA,APC2,RCN1,CCND1,MUC16,RNF220,ST5,SP100,DACT1,XYLT2,ENPP5,ACSL4,RASGEF1A,ZNF365,MYT1,SCN3A,TMEM200B,ENPP4,CAMSAP3,SSH3,COL6A2,C6orf1,RIPK2,SEPT6,PLEKHO1,SYNE2,SAT1,CDCA2,SHROOM3,CORO1C,AXL,INPP4B,PLEKHG1,RGS14,SLC25A30,ISOC1,TNRC6C,OSGIN2,PDIA3,ANO9,PKN1,ETS1,PDIA4,DTX3L,ADD3,IGSF9,SLC27A6,ANKS1B,CTSC,ARSG,CALD1,BAX,ADAM15,ECI2,WWP1,SGCB,TPCN1,MED22,PARP9,PVRL4,ADAMTS2,FMN1,TACC1,RAPGEF2,PIK3R1,MRS2,EIF5A2,CXorf57,SNTB1,CRISPLD2,RPL12,RAB11FIP2,PPM1H,ITGAV,TLL2,TMEM131,BCAM,KIAA1462,TRIM2,GNPDA1,EPHA4,CUL4B,ARFGEF1,NDC80,LMCD1,ITPR2,PDGFB,SPTB,FANCI,PLS3,SUSD2,RPS6KA2,MKRN3,IL6ST,PAPSS1,SLC44A1,ABCA2,ANO4,TLN2,MYBL1,TRAM1,DDX59,NEB,ZNF462,PLK1,THRB,PCGF5,CELSR2,STAU2,CBX6,EZR,CR2,IDH1,SESN1,ZBTB7B,DPYSL3,OPTN,KDM4D,TRIM9,HS6ST1,KLF12,MAP2,P4HA2,ZNF367,ARRDC1,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,UBASH3B,RASA2,FXYD3,PDCL,ADCK5,CNTNAP2,FBLN1,ANO1,B4GALNT1,DAZAP1,IGF1R,SPIN4,FRAS1,KIF13B,FAR2,PLCB2,ABCC1,DPYSL5,CHSY3,PCDH1,PLEKHA6,BTNL9,ZNF320,MGAT4B,SPATA13,SCRIB,EIF2AK1,G2E3,PRX,FOXD2,PVRL2,COL13A1,KBTBD2,ITGA7,PRPS2,SLC2A6,LTBP2,PLD1,ZDBF2,CCNB2,RNF146,USP43,HOXB7,UGP2,TP53,CCDC68,ERBB2,STIL,SYTL2,TTC21B,EFR3A,LMO4,N4BP3,PLCG2,BCL6,PLK4,GLB1L2,ESPN,NOTCH3,SCN2A,CTH,CPD,SIRT1,CLCN3,TMTC1,ERLEC1,AKT1,S100A4,CDC20,PTGER4,ATP13A2,DUOX1,ATP1A1,IDE,PTPRJ,RBL1,ADAMTS14,IRF7,EFNA5,ST3GAL1,LTA4H,AIFM3,ZNF701,NDST3,MAN2B2,ZMAT1,CMAS,COL9A3,PACSIN2,CDH22,GNE,GABRG2,GDF15,CRABP2,AIP,SLC9A2,PPP2R3A,NRP2,SIRPA,FZD6,SH2D4A,FOXP2,ALPP,GTF2F2,FAM63A,BUB1,SYK,ATP2B1,GCNT1,FAH,IGDCC4,DLGAP1,HMMR,RHOA,FBLN5,IFITM3,GUSB,NR3C1,AMFR,PRICKLE1,COL7A1,PRDX4,FAT4,SCG2,ZNF214,NMI,TMC5,FAM117A,ICOSLG,TBC1D4,ARHGEF9,ZBTB33,GOLGB1,LAMP1,SUN1,PPP4R4,HSPG2,SSH1,LGR4,ATP8A1,PJA2,OAT,SLC20A1,NCS1,SESN3,CTGF,OSBPL3,PRICKLE3,RGS3,FOSB,SERINC2,PIK3CA,KCNS3,AOX1,SNX16,ATRNL1,HYLS1,PACSIN1,XKR8,ORAI2,TMEM68,HSPA12A,TNS1,LDB2,POR,AHRR,PLK2,GNPTAB,NKD1,BMP1,DHTKD1,SERPINI1,NFKBIZ,WBSCR27,TRAF5,LZTS1,DDX58,SEMA6B,MRC2,FRMD4A,TBC1D1,DGKQ,KIF23,ISYNA1,PRRG4,MESDC2,DOPEY2,ITGA3,RALGPS2,BHLHE41,SLC16A6,AIM1,RUNDC3B,DAPK1,SORL1,OSTF1,CACNA1D,RIMS2,FAM69A,IGSF3,EPB41L5,GFPT1,KCNJ12,B3GNT7,PRSS23,MFI2,TBC1D8B,ANO6,ANTXR1,GLT8D2,RASA1,MMP15,DGKH,GABRD,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,AGBL5,PCDH19,CABIN1,PER3,IFIH1,NRBP1,SPRED1,SLC2A4,DLGAP5,TRIP10,S100A11,ST14,NLRX1,CAST,IQGAP1,THRA,BROX,ATP2C2,CD274,MNS1,ZFYVE9,APLP2,ACAP2,FAM46A,TRANK1,CNNM4,DAB2IP,PDE4D,EPHB4,NR2C1,NAGA,DOCK4,COG2,CAPN6,UTRN,KIF1C,PRKCQ,PKMYT1,PYGO1,ITPR3,ALCAM,ATP10D,NIN,POPDC3,PPP2R5A,JAK1,DDOST,TSPAN18,NRG1,MLKL,SLC27A3,NR3C2,COBL,DENND5B,WASF3,ARHGEF3,DEPDC1,HAPLN3,CENPI,EPS8,HERC5,PBX3,SEPP1,DNAH3,SIX4,LGALS3BP,E2F7,FAM111A,PHF7,RNF128,PTEN,FUT8,FJX1,SGK3,ATP8B1,ERBB3,SLC16A5,OSGIN1,NCOA2,FARP2,TGIF1,RASGRF1,ARHGEF28,LONRF3,MPP1,ZKSCAN2,PARP4,DIAPH2,FBXO9,GRTP1,AIF1L,FOS,ARSK,KIF11,GPLD1,CDK5RAP1,MAMDC4,ABCB1,PGM2L1,WDR62,NCAPG2,CPEB2,ESPL1,JARID2,RGMA,EXPH5,LTBP1,CASP3,UGT8,CAMKK1,MPP5,KREMEN1,TMC1,CHPF,ZFYVE16,ARHGEF10L,SIPA1L2,LRRC6,GRHL1,ARHGEF37,DPYSL2,CEP78,ANKFN1,DLG1,ANKRD12,TRPC1,POF1B,SUN3,TECR,SLC39A10,MYRIP,BTBD3,CYP1B1,ITCH,ROR1,MAN2A2,ZNF114,UEVLD,MADD,ZNF165,SP6,RAP1GAP,CPPED1,PCSK5,GRN,PEX6,BVES,ETV5,ABCG2,PM20D2,FAM81A,PHLPP1,ZNF432,CA2,COL6A1,LIMCH1,RFX5,C10orf54,ETV7,CCDC88A,SNX7,KDELR1,PODXL2,OXR1,BTN3A2,VWA1,HEATR5A,AMDHD1,RANBP9,XKRX,ONECUT1,UAP1,TMEM30A,RHOBTB2,ALPK3,SHROOM2,JAK3,COL16A1,AFAP1,KLF7,PROM2,CCNE2,NCKAP5,SLC25A24,SORBS1,FAM92A1,PDIA5,COL18A1,IL27RA,MRAS,TDRKH,ARHGEF16,KCTD9,SS18,ZNF687,KIF14,FRYL,TWIST1,ECE1,ZNF525,PTPRU,ERBB2IP,DOCK5,CASP4,ALDH5A1,BHLHB9,TLE1,OVOL1,SPTBN5,ABCA1,PPP2R2D,GCLM,SORT1,ARHGEF11,TGFBR1,COL4A5,NOTUM,INTS8,TRIB2,POMGNT1,SBF1,HMGXB4,HDAC9,IRF2BPL,ADORA1,TAF1B,MLPH,LLGL2,A4GALT,BMP7,TOX2,KIAA0319,IQGAP3,CLIP2,MYO5A,PHF20L1,NR4A1,ASPM,RC3H2,MBNL3,RUNX3,KLHL2,TRIM69,DHRS2,UACA,GRAMD1C,ZMIZ1,SOX8,GEM,AHR,ABCG1,CD33,SNPH |
| 8.296e-03 | -4.79 | platelet dense tubular network membrane | cellular component | GO:0031095 | 9 | 4 | 17570 | 1756 |
ITPR2,ITPR3,ITPR1,EHD1 |
| 8.348e-03 | -4.79 | Acyl-CoA-binding_prot_CS | interpro domains | IPR022408 | 5 | 3 | 18293 | 1814 |
ACBD5,ECI2,DBI |
| 8.348e-03 | -4.79 | Syntrophin | interpro domains | IPR015482 | 5 | 3 | 18293 | 1814 |
SNTA1,SNTB1,SNTB2 |
| 8.348e-03 | -4.79 | Lysosome-assoc_membr_glycop | interpro domains | IPR002000 | 5 | 3 | 18293 | 1814 |
LAMP2,LAMP1,LAMP3 |
| 8.348e-03 | -4.79 | Disulphide_isomerase | interpro domains | IPR005788 | 5 | 3 | 18293 | 1814 |
PDIA3,PDIA6,PDIA4 |
| 8.348e-03 | -4.79 | IGFBP_CNN | interpro domains | IPR012395 | 5 | 3 | 18293 | 1814 |
NOV,CTGF,CYR61 |
| 8.348e-03 | -4.79 | UbiB_dom | interpro domains | IPR004147 | 5 | 3 | 18293 | 1814 |
ADCK5,ADCK3,ADCK2 |
| 8.348e-03 | -4.79 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | MSigDB lists | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | 5 | 3 | 17758 | 1761 |
HMGA1,APOBEC3G,PSIP1 |
| 8.348e-03 | -4.79 | ELVIDGE_HIF2A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF2A_TARGETS_UP | 5 | 3 | 17758 | 1761 |
SORL1,OSTM1,RET |
| 8.348e-03 | -4.79 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3 | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3 | 5 | 3 | 17758 | 1761 |
IGF1R,SOX9,PDIA4 |
| 8.348e-03 | -4.79 | LAU_APOPTOSIS_CDKN2A_DN | MSigDB lists | LAU_APOPTOSIS_CDKN2A_DN | 5 | 3 | 17758 | 1761 |
TIMP3,FAIM,AKT1 |
| 8.435e-03 | -4.78 | V$RORA1_01 | MSigDB lists | V$RORA1_01 | 233 | 35 | 17758 | 1761 |
NCKAP5,SLC25A27,FHDC1,NDRG2,CYP39A1,PSIP1,TSPAN7,CMTM6,NEO1,HDAC9,ZDHHC21,CCDC92,ZNF687,DACT1,STEAP2,ESPN,ACSL4,PIM1,PACSIN1,ZRANB1,BTBD3,CCDC88A,GPR161,CTH,LCA5,BCL9,RGAG1,STRADB,TCF7,LDB2,ZFAND5,GABARAPL1,STK38,ARF6,JARID2 |
| 8.435e-03 | -4.78 | REACTOME_METABOLISM_OF_CARBOHYDRATES | MSigDB lists | REACTOME_METABOLISM_OF_CARBOHYDRATES | 233 | 35 | 17758 | 1761 |
SLC2A4,UGP2,ENO2,HSPG2,SLC25A13,SDC4,HEXB,CALM3,DSE,B4GALT4,SDC1,PRKACA,CHPF,GNS,CALM2,GOT1,PHKA2,NUP85,B3GALT6,CHSY3,HMMR,PGM1,B3GNT7,B3GNT2,GUSB,CALM1,GLCE,HS6ST1,HPSE,PRPS2,MDH1,HS3ST3B1,ST3GAL1,ARSB,NDST3 |
| 8.450e-03 | -4.77 | ION_BINDING | MSigDB lists | ION_BINDING | 266 | 39 | 17758 | 1761 |
PINK1,REPS2,SLC25A13,MTL5,TP53,CALM3,NUCB2,HPCAL4,NCS1,CALM2,RCN1,CA2,STIM1,CABP1,PIM1,S100A13,APOBEC3G,RASGRP1,ERAP2,GCA,KCNIP3,MCTP1,FIGNL1,GCLC,S100A4,CALM1,CDA,PIF1,MAP3K6,CDK5R1,FECH,MMP15,MMP17,STK38,ATP7B,MAP3K5,LTA4H,KLF7,MAPK12 |
| 8.485e-03 | -4.77 | morphogenesis of a branching epithelium | biological process | GO:0061138 | 172 | 28 | 16441 | 1675 |
NKX3-1,GRHL2,ST14,SOX9,TFAP2C,CTSZ,PLXNA1,DAG1,EDNRA,SOCS3,CTNNBIP1,NCOA3,FAT4,NPNT,FGFR2,CSF1,BMP7,SPINT2,DLG1,BAX,HOXB13,SOX8,FZD5,SEMA3A,ETV4,SLC12A2,SPRY2,ADAMTS16 |
| 8.494e-03 | -4.77 | G-protein mediated events | REACTOME pathways | R-HSA-112040 | 47 | 11 | 8202 | 867 |
CALM2,PLA2G4A,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2 |
| 8.507e-03 | -4.77 | cellular response to lipid | biological process | GO:0071396 | 366 | 52 | 16441 | 1675 |
PRKAA2,NKX3-1,IL15,THRA,SOX9,RET,IL18,CCNB1,GSTP1,TFAP4,CXCL16,BMP7,DAB2IP,PDE4D,KLF9,PIM1,WNT3A,NR2C1,PAQR7,THRB,RIPK2,AKT1,NR3C1,FZD4,NR4A1,CASP9,LITAF,PPARA,YES1,PDK3,CD40,ELK1,FZD7,GPLD1,FECH,GNAS,NCOA3,ATP1A1,CDK19,NR1D2,AXL,PTK7,NFKBIA,NR4A3,NR4A2,GPER1,CMPK2,OSR1,NR3C2,RARG,ABCA1,NR2C2 |
| 8.532e-03 | -4.76 | rough endoplasmic reticulum membrane | cellular component | GO:0030867 | 19 | 6 | 17570 | 1756 |
SEC61B,PLOD3,PLOD2,BCAP31,DNAJC3,SUCO |
| 8.532e-03 | -4.76 | lamellipodium membrane | cellular component | GO:0031258 | 19 | 6 | 17570 | 1756 |
PIEZO1,ITGAV,NCKAP1,APC2,ANTXR1,SYNE2 |
| 8.533e-03 | -4.76 | V$OCT1_04 | MSigDB lists | V$OCT1_04 | 225 | 34 | 17758 | 1761 |
CPEB4,THRA,GABRG2,NDUFA4,BCL2L1,PPP2R3A,LMNA,HDAC9,CCND1,FOXP2,PTEN,XYLT2,LMO4,MITF,BCL6,KCNS3,TWIST1,AHCY,TSPAN13,DIXDC1,CACNA1D,NCAM1,SMARCA2,SH3BGRL,SERTAD4,LDB2,TP53INP2,NFIX,NIN,PITX2,RHOBTB2,SP6,ARF6,NR3C2 |
| 8.533e-03 | -4.76 | G2/M Transition | REACTOME pathways | R-HSA-69275 | 115 | 21 | 8202 | 867 |
PLK1,CEP70,FOXM1,MYBL2,PRKAR2B,PKMYT1,CCNB1,BORA,PRKACA,CDK1,OPTN,WEE1,CNTRL,CEP78,PLK4,NEK2,AURKA,TUBG1,NDE1,CEP41,CCNB2 |
| 8.535e-03 | -4.76 | platelet dense granule membrane | cellular component | GO:0031088 | 5 | 3 | 17570 | 1756 |
LAMP2,CD63,ITPR1 |
| 8.535e-03 | -4.76 | lateral loop | cellular component | GO:0043219 | 5 | 3 | 17570 | 1756 |
ERBB2,MPP5,DLG1 |
| 8.570e-03 | -4.76 | NID1 (nidogen 1) | protein interactions | 4811 | 23 | 7 | 16036 | 1726 |
PTPRF,MDK,ITGAV,HSPG2,FBLN1,COL13A1,LGALS3BP |
| 8.570e-03 | -4.76 | STT3B (STT3B, subunit of the oligosaccharyltransferase complex (catalytic)) | protein interactions | 201595 | 23 | 7 | 16036 | 1726 |
RPN2,FBXO6,DDOST,CORO1C,TMEM173,ABCC1,TP53 |
| 8.570e-03 | -4.76 | CSF1R (colony stimulating factor 1 receptor) | protein interactions | 1436 | 23 | 7 | 16036 | 1726 |
YES1,ITGAV,INPP5D,CSF1,RASA1,PIK3R1,SOCS3 |
| 8.570e-03 | -4.76 | negative regulation of actin filament depolymerization | biological process | GO:0030835 | 36 | 9 | 16441 | 1675 |
SWAP70,PLEKHH2,ADD1,EPS8,TRIOBP,SPTBN5,TMOD2,SHROOM2,SPTB |
| 8.570e-03 | -4.76 | protein kinase B signaling | biological process | GO:0043491 | 36 | 9 | 16441 | 1675 |
NKX3-1,AKT1,PTEN,AXL,SOX9,PIK3CA,PIK3C2B,CD40,MERTK |
| 8.570e-03 | -4.76 | activation of JUN kinase activity | biological process | GO:0007257 | 36 | 9 | 16441 | 1675 |
MAP3K9,MDFIC,DAB2IP,MAP3K5,PKN1,MAP3K6,SYK,GAB1,MDFI |
| 8.574e-03 | -4.76 | CREB phosphorylation through the activation of Ras | REACTOME pathways | R-HSA-442742 | 29 | 8 | 8202 | 867 |
CALM2,RASGRF1,RPS6KA2,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D |
| 8.574e-03 | -4.76 | Smooth Muscle Contraction | REACTOME pathways | R-HSA-445355 | 29 | 8 | 8202 | 867 |
MYL9,CALM2,SORBS1,CALD1,CALM1,CALM3,MYL12B,MYL12A |
| 8.581e-03 | -4.76 | growth | biological process | GO:0040007 | 408 | 57 | 16441 | 1675 |
EMX1,CDKN1C,GRHL2,ADD1,IQGAP1,SOX9,LRP4,TP53,TEC,BCL2L1,CCNB1,SEPP1,PDGFB,STIL,NRP2,NOV,PTEN,BMP7,FLRT3,ADAM15,PDE4D,WNT3A,SLC12A2,SPRY2,SOCS5,EPB41L5,SALL4,FMN1,BCL9,ASPM,RC3H2,TFAP2C,KLK6,PRKCQ,ERBB2IP,ICMT,ALCAM,NUBP1,C3orf58,FZD7,GNAS,NCOA3,TIMP3,FGFR2,CSF1,SLC9A6,PTK7,AURKA,EFNA5,ITGAV,GDF11,ZMIZ1,NCAPG2,CCNB2,SEMA3A,COBL,RARG |
| 8.583e-03 | -4.76 | APPBP2 (amyloid beta precursor protein (cytoplasmic tail) binding protein 2) | protein interactions | 10513 | 92 | 18 | 16036 | 1726 |
MFSD3,PRKAA2,LONRF3,FAM92A1,PYROXD2,ERO1A,CALM3,GSTP1,APPBP2,ANKRD10,GALNT3,RNF128,ZCCHC12,CDK16,DHRS2,AHCY,KLF11,PCSK5 |
| 8.609e-03 | -4.75 | renal system process | biological process | GO:0003014 | 97 | 18 | 16441 | 1675 |
MYO5B,PRKAR2B,PKN1,PRKACA,PDGFB,EMP2,FAS,GNAS,ITGA3,ADORA1,RAB11FIP2,WFS1,SGK1,LGMN,F2R,F2RL1,SULF2,PCSK5 |
| 8.619e-03 | -4.75 | GGGCATT,MIR-365 | MSigDB lists | GGGCATT,MIR-365 | 107 | 19 | 17758 | 1761 |
LAMP2,ARMCX3,SNTB2,COL7A1,ETS1,TP53INP2,SIX4,HDAC9,ADD3,AMMECR1,SGK3,BMP1,SGK1,NR4A2,GRAMD1C,MYLIP,NR3C2,SOCS5,TLL2 |
| 8.621e-03 | -4.75 | male gonad development | biological process | GO:0008584 | 119 | 21 | 16441 | 1675 |
REC8,COL9A3,NKX3-1,ASPM,SOX9,TFAP2C,TGFBR1,BCL2L1,FNDC3A,SDC1,SIX4,PRDX4,SGPL1,CCND1,PITX2,LRRC6,HOXA9,CTSV,CST3,BAX,SOX8 |
| 8.621e-03 | -4.75 | development of primary male sexual characteristics | biological process | GO:0046546 | 119 | 21 | 16441 | 1675 |
REC8,COL9A3,NKX3-1,ASPM,SOX9,TFAP2C,TGFBR1,BCL2L1,FNDC3A,SDC1,SIX4,PRDX4,SGPL1,CCND1,PITX2,LRRC6,HOXA9,CTSV,CST3,BAX,SOX8 |
| 8.636e-03 | -4.75 | respiratory tube development | biological process | GO:0030323 | 180 | 29 | 16441 | 1675 |
THRB,HES1,ADAMTS2,HECA,GRHL2,EPAS1,THRA,SOX9,RC3H2,CTSZ,GPSM2,SAV1,NPHP3,NFIB,DAG1,CRISPLD2,PDGFA,TNS3,HS6ST1,ITGA3,CTGF,FGFR2,PTK7,TMBIM6,PDE4D,PLOD3,LTA4H,SPRY2,PCSK5 |
| 8.636e-03 | -4.75 | regulation of transmembrane transporter activity | biological process | GO:0022898 | 180 | 29 | 16441 | 1675 |
PPIF,RASGRF1,TCAF1,FXYD3,CALM1,UTRN,CALM3,ATP1B1,ANO9,PRKACA,CACNB4,WWP2,CALM2,GNB5,STIM1,CABP1,PLCG2,NETO2,DAPK1,CAB39,FXYD5,TWIST1,STK39,PDE4D,ATP1B3,FHL1,CACNA1D,MYO5A,CHP1 |
| 8.652e-03 | -4.75 | regulation of mitotic nuclear division | biological process | GO:0007088 | 134 | 23 | 16441 | 1675 |
PLK1,DLGAP5,CIT,PTTG1,CDC20,RGCC,NUSAP1,PKMYT1,ANLN,PDGFB,KIF11,BORA,IGF1R,PTEN,FGFR2,BMP7,CDCA5,NEK2,AURKA,BUB1,CENPE,UBE2C,ESPL1 |
| 8.664e-03 | -4.75 | ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) | protein interactions | 25 | 208 | 34 | 16036 | 1726 |
BIN1,SORBS1,UBASH3B,TP53,ERBB2,BCL2L1,REPS1,SLC9A2,SH3KBP1,BMP2K,ST5,SH3BP1,ADAM15,CDKN1B,ERBB3,PDE4D,CKAP4,DDB2,MBP,PLSCR1,CASP9,PIK3R1,FOS,BCAR1,CDK1,PSMA4,RASA1,SOCS3,NCOA3,PLCG1,JAK1,NFKBIA,GRIN2D,LRRK1 |
| 8.674e-03 | -4.75 | positive regulation of transport | biological process | GO:0051050 | 876 | 111 | 16441 | 1675 |
LAMP1,EXPH5,ILDR1,SORBS1,ATP8A1,TP53,PKP2,ERBB2,IL18,SYTL4,CD274,CAMK1D,PRKACA,PDGFB,SDC1,BCAP31,NCS1,SYTL2,CALM2,RAB15,CDH1,STIM1,DACT1,SIVA1,DPYSL2,PLCG2,DLG1,TRPC1,CDH3,TWIST1,TSPAN1,RAB27B,MYRIP,F2R,RASGRP1,CHP1,SIRT1,AKT1,PTGER4,NBPF3,EZR,PRKCQ,ATP1B1,ABR,IRS2,PLCG1,DNM1L,WFS1,AXL,NOD2,NRG1,RAP1GAP,F2RL1,ABCA1,DDX58,PRSS8,SCN5A,TCAF1,PINK1,BMF,NKX3-1,LGALS3,CD63,HLA-E,SDC4,CALM3,TGFBR1,MERTK,IL18R1,ANO1,FGF19,KIF5B,CARD8,ADORA1,CA2,ADRBK1,GATA2,KCNN4,FAM20B,SGK3,BAX,SGK1,SORL1,MAPK11,CACNA1D,WNT3A,SYK,HES1,RAB3B,RHOA,CALM1,PIK3R1,ANO6,RGCC,CDK5R1,GPLD1,SYT7,TMEM30A,NFKBIA,NR4A3,ARRB1,STK39,ITGAV,GPER1,FHL1,ATP1B3,FZD5,JAK3,TMEM173,ABCG1,EHD1 |
| 8.676e-03 | -4.75 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | 854 | 106 | 17758 | 1761 |
CCNI,SORBS1,NQO1,BROX,CNOT8,PTTG1,DDR1,KCTD9,IER3,PSMD1,CDH1,UBE2T,NPNT,IL6ST,FRYL,TSPAN6,REEP1,AKR1B1,CDH3,TWIST1,CRY2,PIK3CD,DLG3,MYBL1,SNX10,CTDSP2,DVL2,MBP,FIGNL1,CASP9,CDC20,NUSAP1,GLO1,RAD17,CD40,PTGFRN,SLC25A5,SNX12,SP4,COL12A1,NFIX,ATP1A1,LIMK1,MMP17,STK38,PRKCDBP,ADIPOR1,SLC27A1,NR2C2,MAPK12,PCSK5,TM2D2,NFKBIE,LRRFIP2,ITGA6,FXYD3,DNAJB2,RAB23,GTF3A,FBLN1,IL18R1,HPCAL4,LMNA,SIRPA,CTNNBIP1,B3GALNT1,MDM1,PHF7,TFAP2A,FAM63A,TRIM21,AHCY,SELK,IGFBP2,BUB1,KLF9,NCAM1,SYK,ALDH3A2,MED22,MYO5A,KDELR1,AMOTL2,IFITM3,CRB3,LPGAT1,MPP1,PIK3R1,FOS,STX3,CNTNAP1,GNAS,ONECUT1,SWAP70,SLC4A4,NR1D2,ACVRL1,TWSG1,HNRNPH2,NMI,CDCA7L,AURKA,GRIN2D,MDH1,HOXB13,ITGAV |
| 8.696e-03 | -4.74 | MARSON_BOUND_BY_E2F4_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_E2F4_UNSTIMULATED | 692 | 88 | 17758 | 1761 |
ARHGAP11A,CASP3,DLGAP5,SPC25,IQGAP1,TAP1,NDC80,TP53,TESK2,DNAJB11,NUF2,STIL,BARD1,MNS1,CENPN,KCTD9,FANCI,SIVA1,PASK,TMEM143,PLK4,VAT1,RPN2,PLK1,LOC81691,CENPA,FIGNL1,PBK,CDC20,SLC11A2,NUSAP1,CDCA2,DNAJB14,PIF1,ANLN,CCNF,KCTD2,CDK1,PRIM1,TAPBP,DDOST,GDE1,RBL1,CDK19,ZNF367,AGFG2,DEPDC1,ALDH6A1,HJURP,CIT,DCAF7,CENPI,CDCA8,ERI2,KIF23,NTAN1,TOP2A,TFAP4,FAM111A,MDM1,ATP5H,RANBP1,NEK2,OPN3,BUB1,ZMYM1,NUP85,HMMR,SHMT1,KIF20A,ASPM,MYBL2,CCDC34,STMN3,BORA,NUBP1,KIF11,FAM64A,TIMM8A,DCK,CDCA5,AURKA,CENPE,ETAA1,UBE2C,CCNB2,ESPL1,MELK |
| 8.696e-03 | -4.74 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 99 | 19 | 16036 | 1726 |
SIRT1,CASP3,AKT1,RPS6KA1,UBASH3B,CALM1,NUB1,PKN1,HDAC6,PRKACA,ARHGEF40,CDK1,SPTB,CDK5R1,PPP2R5A,SGK1,MAPK11,SYK,MAPK12 |
| 8.708e-03 | -4.74 | ST_P38_MAPK_PATHWAY | MSigDB lists | ST_P38_MAPK_PATHWAY | 37 | 9 | 17758 | 1761 |
MAPKAPK2,AKT1,DUSP10,MAPK11,MAP3K5,ELK1,HSPB1,MAPK12,NR2C2 |
| 8.708e-03 | -4.74 | GNF2_VAV1 | MSigDB lists | GNF2_VAV1 | 37 | 9 | 17758 | 1761 |
HLA-B,HLA-E,HLA-F,INPP5D,OSTF1,ARHGDIB,GRK6,HLA-C,PIK3CD |
| 8.708e-03 | -4.74 | HAN_JNK_SINGALING_DN | MSigDB lists | HAN_JNK_SINGALING_DN | 37 | 9 | 17758 | 1761 |
COL6A2,COL6A1,CD9,ISYNA1,LIFR,ABCA1,AHR,SOCS3,FAS |
| 8.708e-03 | -4.74 | GEISS_RESPONSE_TO_DSRNA_UP | MSigDB lists | GEISS_RESPONSE_TO_DSRNA_UP | 37 | 9 | 17758 | 1761 |
IGFBP6,PLAUR,NFKBIA,NMI,SAT1,TAP1,IFIT1,AFAP1,ELF3 |
| 8.708e-03 | -4.74 | GNF2_CD97 | MSigDB lists | GNF2_CD97 | 37 | 9 | 17758 | 1761 |
JAK1,IQGAP1,HLA-E,HLA-F,STK38,LITAF,PTGER4,EFHD2,OSTF1 |
| 8.708e-03 | -4.74 | VARELA_ZMPSTE24_TARGETS_UP | MSigDB lists | VARELA_ZMPSTE24_TARGETS_UP | 37 | 9 | 17758 | 1761 |
MAPKAPK2,KLF3,BCL2L1,C15orf39,SESN1,SLC20A1,LEPR,TIPRL,CYP26A1 |
| 8.708e-03 | -4.74 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | 37 | 9 | 17758 | 1761 |
RASGRF1,PDGFC,CTHRC1,RBL1,PLOD2,DPYSL2,UBE2C,LTBP3,CDK1 |
| 8.708e-03 | -4.74 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | MSigDB lists | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 37 | 9 | 17758 | 1761 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D |
| 8.712e-03 | -4.74 | HENDRICKS_SMARCA4_TARGETS_DN | MSigDB lists | HENDRICKS_SMARCA4_TARGETS_DN | 50 | 11 | 17758 | 1761 |
LGALS3,CKAP2,HEXB,TACSTD2,ARHGDIB,LTBP2,PER3,SEPP1,SPRY2,EFNB1,NRP2 |
| 8.712e-03 | -4.74 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | MSigDB lists | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | 50 | 11 | 17758 | 1761 |
IRS2,SLC2A4,SORBS1,RPS6KA2,AKT1,PTEN,RPS6KA1,PIK3R1,PIK3CA,SERPINB6,PIK3CD |
| 8.726e-03 | -4.74 | gastrointestinal_stromal_tumour | COSMIC cancer mutations | gastrointestinal_stromal_tumour | 78 | 15 | 17775 | 1757 |
GNAS,CDH1,AKT1,PTEN,ATP9A,CASP9,SLC2A6,PIK3CA,TP53,ABCA2,NUCB2,IDH1,BCAR1,GNA11,LZTS1 |
| 8.750e-03 | -4.74 | insulin-like growth factor I binding | molecular function | GO:0031994 | 9 | 4 | 16491 | 1673 |
IGFBP2,ITGAV,IGF1R,IGFBP6 |
| 8.750e-03 | -4.74 | nitric-oxide synthase regulator activity | molecular function | GO:0030235 | 9 | 4 | 16491 | 1673 |
CALM3,CALM2,AKT1,CALM1 |
| 8.750e-03 | -4.74 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor | molecular function | GO:0016723 | 9 | 4 | 16491 | 1673 |
CYB561,STEAP1,CYBRD1,STEAP2 |
| 8.750e-03 | -4.74 | G-protein coupled glutamate receptor binding | molecular function | GO:0035256 | 9 | 4 | 16491 | 1673 |
CALM3,CALM2,CABP1,CALM1 |
| 8.750e-03 | -4.74 | natural killer cell lectin-like receptor binding | molecular function | GO:0046703 | 9 | 4 | 16491 | 1673 |
ULBP2,HLA-E,MICB,RAET1L |
| 8.750e-03 | -4.74 | peptidyl-proline 4-dioxygenase activity | molecular function | GO:0031545 | 9 | 4 | 16491 | 1673 |
EGLN3,P4HA2,P4HA3,EGLN1 |
| 8.751e-03 | -4.74 | myxoid-round_cell | COSMIC cancer mutations | myxoid-round_cell | 100 | 18 | 17775 | 1757 |
SPEF2,SMARCA2,ARAP3,AKT1,GNE,TP53,VARS2,IDH1,SPTB,GNAS,SS18,CDH1,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 8.751e-03 | -4.74 | soft_tissue-fat-liposarcoma-myxoid-round_cell | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-myxoid-round_cell | 100 | 18 | 17775 | 1757 |
SPEF2,SMARCA2,ARAP3,AKT1,GNE,TP53,VARS2,IDH1,SPTB,GNAS,SS18,CDH1,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 8.753e-03 | -4.74 | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | MSigDB lists | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | 85 | 16 | 17758 | 1761 |
TIMP2,MBP,LGALS3,EPHA4,SAT1,TAP1,ARHGDIB,IFIT3,FBLN1,HDAC9,CDKN2C,PITX2,NOV,PLOD2,LTBP2,SERPINB1 |
| 8.753e-03 | -4.74 | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | MSigDB lists | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | 85 | 16 | 17758 | 1761 |
PLK1,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,PRKACA,CDK1,RPS6KA2,IGF1R,PIK3CA,BUB1,MAPK11,PIK3CD,CCNB2,MAPK12 |
| 8.758e-03 | -4.74 | antigen processing and presentation of peptide antigen | biological process | GO:0048002 | 188 | 30 | 16441 | 1675 |
SEC23A,SEC61B,PSMB4,HLA-E,PSME2,HLA-F,UBE2A,TAP1,PDIA3,KIF23,PSMD10,PSME1,KIF11,PSMA4,BCAP31,HLA-A,MARCH8,DCTN6,CTSL,HLA-B,TAPBP,PSMD1,AP1M2,CTSV,ERAP1,ITGAV,HLA-C,CENPE,LGMN,ERAP2 |
| 8.758e-03 | -4.74 | protein N-linked glycosylation | biological process | GO:0006487 | 188 | 30 | 16441 | 1675 |
GFPT1,SEC23A,CMAS,MGAT4B,GNE,PDIA3,CTSZ,COL7A1,NANS,MGAT5B,B4GALT4,MCFD2,MAN2A2,FUCA1,UAP1,DDOST,SERPINA1,CTSC,ALG13,MGAT4A,DOLPP1,GNPTAB,FUT8,UBE2J1,RPN2,CTSA,LMAN1,ST3GAL1,PPP6R1,MGAT5 |
| 8.762e-03 | -4.74 | pituitary-adenoma-non_functioning | COSMIC cancer mutations | pituitary-adenoma-non_functioning | 14 | 5 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,RET,PIK3CA |
| 8.762e-03 | -4.74 | ACTH | COSMIC cancer mutations | ACTH | 14 | 5 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,RET,PIK3CA |
| 8.762e-03 | -4.74 | pituitary-adenoma-ACTH | COSMIC cancer mutations | pituitary-adenoma-ACTH | 14 | 5 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,RET,PIK3CA |
| 8.762e-03 | -4.74 | soft_tissue-blood_vessel-haemangioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-epithelioid | 14 | 5 | 17775 | 1757 |
PLCG1,AKT1,IDH1,PTEN,PIK3CA |
| 8.763e-03 | -4.74 | CAGTGTT,MIR-141,MIR-200A | MSigDB lists | CAGTGTT,MIR-141,MIR-200A | 300 | 43 | 17758 | 1761 |
CCNE2,RMND5A,CDK17,FRMD4A,FRMD6,ZCCHC24,PHLPP1,SLC20A1,FAM46C,NRP2,IRF2BPL,TNS3,SIPA1L2,MDM1,WDR44,LHX6,STEAP2,DIXDC1,TRAM1,MYRIP,THRB,CYP26B1,SIRT1,CPD,ATL1,STAT4,AK4,TFAP2C,KIF1C,ATP1B1,RAB38,SP4,IRS2,PITX2,HLF,FGFR2,PHLPP2,DOLPP1,RAP2C,AGFG2,ACOT7,HOXC13,NR2C2 |
| 8.774e-03 | -4.74 | reproductive process | biological process | GO:0022414 | 1171 | 144 | 16441 | 1675 |
CCNI,LGR4,EPAS1,AK7,GNPDA1,HEXB,CCNB1,PDGFB,SDC1,CYP1A1,HSF2,RPS6KA2,LRRC6,PAQR5,FOSB,DLG1,AKR1B1,CLDN4,TIPARP,THRB,SMARCA2,SPEF2,CELSR2,TFAP2C,CCNF,IDH1,CDK1,HS6ST1,HOXA9,GAB1,E2F8,MAFF,NR2C2,PCSK5,GRN,CDKN1C,SERPINE2,SOX9,ETV5,MTL5,FBLN1,MERTK,LMNA,B4GALNT1,DAZAP1,ITGA3,IGF1R,CYR61,GATA2,SPIN4,MDFI,PAQR7,CYP26B1,REC8,TESK1,ATP8B3,ANTXR1,GNAS,NCOA3,PVRL2,PLPP3,CSF1,UTP14C,SFMBT1,HOOK1,RARG,APOL2,COL16A1,EGLN1,GRHL2,ST14,CAST,THRA,PTTG1,TESK2,ERBB2,TDRKH,BCL2L1,PRKACA,EMP2,DDR1,BCAP31,MNS1,CCND1,APLP2,BCL6,PLK4,ACSL4,GPX4,SIRT1,AKT1,FZD4,IGSF8,PYGO1,SOCS3,AXL,OVOL1,COL9A3,NKX3-1,CIT,CENPI,TGFBR1,SBF1,SEPP1,ETS1,SIX4,TEAD3,SGPL1,IRF2BPL,E2F7,ITGB8,PTEN,CDK16,TOX2,CST3,BAX,CD9,UBE2J1,TMBIM6,IGFBP2,CITED2,CRTAP,HES1,ADAMTS2,ASPM,EIF5A2,GRIN1,UBE2A,DIAPH2,FNDC3A,BBS2,FOS,PRDX4,PITX2,FGFR2,CTSV,SPINT2,ARRB1,HOXB13,ZMIZ1,SOX8,OSR1,FZD5,AHR |
| 8.782e-03 | -4.74 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 193 | 30 | 17758 | 1761 |
MRPS33,TIMP2,ALDH2,MMD,EPAS1,MRPS15,GUSB,MPP1,HEXB,HMGN3,TEX2,GTF3A,MGST2,SLC25A5,IDH1,ERP29,SESN1,TP53I3,PRDX4,AMZ2,GNAS,PTER,PRPS2,COL6A1,VAT1,MDH1,AHCY,HSPB1,CCDC88A,FAM69A |
| 8.782e-03 | -4.74 | GSE17721_LPS_VS_CPG_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_24H_BMDM_DN | 193 | 30 | 17758 | 1761 |
ALDH2,SLC37A1,SPC25,KIF20A,TRIP10,ITCH,C3orf52,FHDC1,LITAF,ABCG2,TGFBR1,MRAS,CNTNAP2,PJA2,CDK1,BMP2K,NIN,SWAP70,RPL12,RND3,UEVLD,SLC16A6,LMO4,SLC44A1,UBE2J1,TMEM51,TWIST1,PDIA6,CCNB2,TMEM131 |
| 8.782e-03 | -4.74 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_UP | 193 | 30 | 17758 | 1761 |
CASP3,PCDH1,IL15RA,HLA-E,SDC4,OSGIN2,LITAF,STMN3,HTATIP2,SLC1A3,PDK3,EPHA1,CRABP2,ALCAM,FAM46C,SAC3D1,DPYSL3,ARHGEF10L,CNTNAP1,CDKN2C,CPNE2,CACHD1,GPRC5B,POF1B,AKR1B1,RTKN2,TINAGL1,ECE1,ETV4,GAB1 |
| 8.782e-03 | -4.74 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 193 | 30 | 17758 | 1761 |
MX1,SYPL1,SEMA6B,PDGFC,PAPSS2,PLSCR1,IQGAP1,ITCH,ERBB2IP,PHLPP1,MAP3K6,NRP2,LMNA,RAD23A,AKIRIN1,B3GALNT1,SWAP70,CYP1A1,FAM64A,PVRL2,ANKRD6,UEVLD,SIPA1L1,PPP4R1,COL6A1,CD9,OPN3,MELK,GPR161,CYP1B1 |
| 8.782e-03 | -4.74 | GSE360_DC_VS_MAC_L_DONOVANI_UP | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_UP | 193 | 30 | 17758 | 1761 |
CASP3,TXN,PTPN9,PPFIBP2,LITAF,CTSZ,HMGN3,TP53I11,GTF2A2,GSTP1,CD83,BCAR3,PDGFA,TIMP3,CA2,LYPD3,CTSC,NFKBIA,NMI,AKR1B1,CSTF2,ADAM15,AHCY,MDH1,TLN2,PTPRE,SMYD5,PPP6R1,RBMS2,LAMP3 |
| 8.782e-03 | -4.74 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | 193 | 30 | 17758 | 1761 |
MX1,IL15RA,IL15,IFITM3,USP18,CASP9,FURIN,TAP1,POMGNT1,IFIT3,RNF19B,CASP4,LGALS3BP,AKIRIN1,ZFYVE16,HLA-B,TAPBP,PSMD1,SHROOM3,NMI,GTF2F2,TRIM21,IRF7,PIM1,HLA-C,CMPK2,UBE2C,IFIH1,ABCA1,FAH |
| 8.782e-03 | -4.74 | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | 193 | 30 | 17758 | 1761 |
GRN,LAMP1,SUN2,LASP1,SLC37A1,IL15RA,SNTB2,ITGA6,CASP9,HEXB,HTATIP2,ITPR3,DOCK5,CDK1,FUCA1,SCARB2,DOPEY2,PQLC2,KCNN4,CORO1C,STK38,SGK1,TNFRSF12A,HMGA1,TMEM37,PHKA2,PLCB2,NAGA,TOB1,ABCG1 |
| 8.782e-03 | -4.74 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | 193 | 30 | 17758 | 1761 |
LAMP1,FADS2,TGIF1,KCNIP3,SLC39A8,BLVRB,ARL4C,STMN3,MRAS,PDK3,DSE,SDC1,TCEAL8,FAM46C,ARSK,BARD1,NCS1,TMCC3,DPYSL3,PLS3,GNS,HLA-B,WEE1,POPDC3,DNM1L,SLC16A6,SECTM1,BUB1,SGCB,TLE6 |
| 8.782e-03 | -4.74 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | 193 | 30 | 17758 | 1761 |
DDB2,KIF20A,EPAS1,ITCH,CASP9,CDC20,PDCL,NUSAP1,BLVRA,MGST2,ITPR2,SLC25A5,FECH,DNM1L,PPP4R1,FUT8,DHTKD1,AURKA,BUB1,CENPE,GLA,PDIA6,SERPINB1,CCNB2,ESPL1,MELK,MYO5A,IGSF3,FAH,GOLGB1 |
| 8.789e-03 | -4.73 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | 177 | 28 | 17758 | 1761 |
BIN1,SYPL1,ZNF395,CKAP2,SEPT6,EZR,SAV1,TRIB2,ETS1,BARD1,FAM46C,WEE1,NCOA3,SWAP70,ADD3,BANK1,PAIP2B,PLCG2,ITPR1,TLE1,TSPAN13,PIK3C2B,SLC25A38,TRAF5,RASGRP1,PKIA,SMAGP,DENND5B |
| 8.789e-03 | -4.73 | GSE2706_UNSTIM_VS_2H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_DN | 177 | 28 | 17758 | 1761 |
IL15RA,RAPGEF2,STAT4,PLAUR,LYRM1,SDC4,TAP1,PTGER4,IFIT3,HERC6,TP53INP2,SOCS3,GALNT3,BTG3,UAP1,GRHL1,MFSD2A,ALG13,NFKBIA,NR4A3,DRAM1,NFKBIZ,HS3ST3B1,GEM,CMPK2,MAFF,ESPL1,EHD1 |
| 8.790e-03 | -4.73 | transcription factor activity, direct ligand regulated sequence-specific DNA binding | molecular function | GO:0098531 | 49 | 11 | 16491 | 1673 |
THRB,NKX3-1,NR1D2,THRA,NR4A1,PPARA,NR4A3,NR4A2,GPER1,RARG,AHR |
| 8.790e-03 | -4.73 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | molecular function | GO:0004879 | 49 | 11 | 16491 | 1673 |
THRB,NKX3-1,NR1D2,THRA,NR4A1,PPARA,NR4A3,NR4A2,GPER1,RARG,AHR |
| 8.792e-03 | -4.73 | sodium ion transmembrane transport | biological process | GO:0035725 | 90 | 17 | 16441 | 1675 |
SCN5A,ANO6,ATP1B1,SLC20A1,SLC8B1,SLC9A2,SLC9A7,SCNN1A,ATP1A1,SLC4A4,KCNK1,SLC9A6,CNNM4,ATP1B3,SCN2A,SHROOM2,SLC12A2 |
| 8.795e-03 | -4.73 | Activation of NMDA receptor upon glutamate binding and postsynaptic events | REACTOME pathways | R-HSA-442755 | 41 | 10 | 8202 | 867 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,PRKACA |
| 8.797e-03 | -4.73 | PROVENZANI_METASTASIS_UP | MSigDB lists | PROVENZANI_METASTASIS_UP | 185 | 29 | 17758 | 1761 |
LAMP1,SGCE,ZWINT,SNTB2,SAT1,LMCD1,GDF15,GALNT7,BORA,CENPN,CDK1,CARD10,VPS26A,PDIA4,PRIM1,CDKN2C,TNS3,RBM47,CTSC,PRCP,LRIG1,AKR1B1,PRKCDBP,CADPS2,TRAF5,LTA4H,BTBD3,SPRY2,MCCC2 |
| 8.797e-03 | -4.73 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | 185 | 29 | 17758 | 1761 |
ARHGAP11A,SPRED1,ZWINT,NQO1,CIT,MBNL3,MYBL2,OSGIN2,CDCA2,NUSAP1,GPSM2,SLC9A2,CDKN2C,TOP2A,FAM111A,WEE1,MID1IP1,UAP1,HNRNPH2,NEK2,PLK4,AURKA,GOT1,STK39,UBE2C,E2F8,CRTAP,METAP2,SNX7 |
| 8.805e-03 | -4.73 | regulation of ion transport | biological process | GO:0043269 | 579 | 77 | 16441 | 1675 |
ATP8A1,CACNA2D2,PKP2,PRKACA,CACNB4,PDGFB,CALM2,NKAIN3,STIM1,CABP1,DPYSL2,PLCG2,KCNS3,DLG1,TRPC1,CRY2,TWIST1,PDE4D,TMEM37,ACSL4,SCN2A,F2R,SCN3A,CHP1,PPIF,CLCN3,KCNIP3,AKT1,UTRN,ATP1B1,IRS2,PLCG1,ATP1A1,WFS1,CAB39,SARAF,PRSS8,TCAF1,SCN5A,PINK1,LGALS3,SERPINE2,CD63,UBASH3B,FXYD3,CALM3,ANO9,ANO1,WWP2,KIF5B,SNTA1,GNB5,CA2,ADORA1,BAX,SGK3,DAPK1,SGK1,FXYD5,TSPAN13,CACNA1D,SYK,TPCN1,MYO5A,KCNJ12,RASGRF1,RHOA,RAB3B,CALM1,ANO6,GRIN1,NETO2,STK39,FHL1,ATP1B3,GPER1,JAK3 |
| 8.808e-03 | -4.73 | ADD2 (adducin 2 (beta)) | protein interactions | 119 | 13 | 5 | 16036 | 1726 |
ADD1,PRKACA,ANKRD29,DEF6,CALM1 |
| 8.808e-03 | -4.73 | CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) | protein interactions | 1576 | 13 | 5 | 16036 | 1726 |
PRKACA,POR,AMFR,CYB5A,PGRMC1 |
| 8.808e-03 | -4.73 | PGM3 (phosphoglucomutase 3) | protein interactions | 5238 | 13 | 5 | 16036 | 1726 |
PGM1,GLO1,LACTB2,UAP1,DCP2 |
| 8.808e-03 | -4.73 | BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) | protein interactions | 60468 | 13 | 5 | 16036 | 1726 |
ARRB1,NFE2L3,MAFF,BCL6,NFE2L1 |
| 8.808e-03 | -4.73 | HBEGF (heparin-binding EGF-like growth factor) | protein interactions | 1839 | 13 | 5 | 16036 | 1726 |
FBLN1,CD82,LTBP3,CD9,BCL6 |
| 8.808e-03 | -4.73 | TAP2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 6891 | 13 | 5 | 16036 | 1726 |
TAPBP,HLA-C,HLA-E,HLA-A,TAP1 |
| 8.808e-03 | -4.73 | DNM1 (dynamin 1) | protein interactions | 1759 | 72 | 15 | 16036 | 1726 |
BIN1,IRF2BPL,PLCG1,PACSIN2,LYPD6,PIK3R1,GRIN1,SH3BP4,ARRB1,GRIN2D,CABIN1,CTTN,PACSIN1,ASB13,SH3KBP1 |
| 8.814e-03 | -4.73 | thyroid-adenoma-nodule-goitre | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre | 57 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 8.882e-03 | -4.72 | P-type_ATPase_N | interpro domains | IPR032631 | 14 | 5 | 18293 | 1814 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 8.882e-03 | -4.72 | RasGAP_CS | interpro domains | IPR023152 | 14 | 5 | 18293 | 1814 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 8.882e-03 | -4.72 | TF_A-like/BEX-like | interpro domains | IPR021156 | 14 | 5 | 18293 | 1814 |
TCEAL8,NGFRAP1,BEX2,TCEAL4,WBP5 |
| 8.882e-03 | -4.72 | P-type_ATPase_IV | interpro domains | IPR006539 | 14 | 5 | 18293 | 1814 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 8.882e-03 | -4.72 | P_typ_ATPase_c | interpro domains | IPR032630 | 14 | 5 | 18293 | 1814 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 8.882e-03 | -4.72 | REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 14 | 5 | 17758 | 1761 |
FGD6,ARAP3,ARF6,RALBP1,FGD1 |
| 8.882e-03 | -4.72 | ENDOPLASMIC_RETICULUM_LUMEN | MSigDB lists | ENDOPLASMIC_RETICULUM_LUMEN | 14 | 5 | 17758 | 1761 |
RCN1,ERAP1,ERAP2,PDIA4,PDIA5 |
| 8.882e-03 | -4.72 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | 14 | 5 | 17758 | 1761 |
B3GNT7,B3GNT2,B4GALT4,ST3GAL1,FUT8 |
| 8.882e-03 | -4.72 | PROTEIN_TETRAMERIZATION | MSigDB lists | PROTEIN_TETRAMERIZATION | 14 | 5 | 17758 | 1761 |
ALDH5A1,IGF1R,AASS,TP53,CDA |
| 8.882e-03 | -4.72 | CASTELLANO_NRAS_TARGETS_DN | MSigDB lists | CASTELLANO_NRAS_TARGETS_DN | 14 | 5 | 17758 | 1761 |
RPS6KA2,NCAM1,LIMK1,PLEKHO1,PKIA |
| 8.882e-03 | -4.72 | MATZUK_POST-IMPLANTATION_AND_POST-PARTUM | MSigDB lists | MATZUK_POST-IMPLANTATION_AND_POST-PARTUM | 14 | 5 | 17758 | 1761 |
DAZAP1,FZD4,CSF1,ABCA1,NR2C2 |
| 8.883e-03 | -4.72 | copper ion import | biological process | GO:0015677 | 9 | 4 | 16441 | 1675 |
SLC11A2,STEAP1,ATP7B,STEAP2 |
| 8.883e-03 | -4.72 | carnitine shuttle | biological process | GO:0006853 | 9 | 4 | 16441 | 1675 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 8.883e-03 | -4.72 | positive regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902101 | 9 | 4 | 16441 | 1675 |
PLK1,DLGAP5,PTEN,ESPL1 |
| 8.883e-03 | -4.72 | protein maturation by protein folding | biological process | GO:0022417 | 9 | 4 | 16441 | 1675 |
WFS1,AIP,ERO1A,PRDX4 |
| 8.883e-03 | -4.72 | positive regulation of defense response to bacterium | biological process | GO:1900426 | 9 | 4 | 16441 | 1675 |
KLK7,KLK5,F2RL1,NOD2 |
| 8.883e-03 | -4.72 | positive regulation of mitotic sister chromatid separation | biological process | GO:1901970 | 9 | 4 | 16441 | 1675 |
PLK1,DLGAP5,PTEN,ESPL1 |
| 8.883e-03 | -4.72 | regulation of transposition | biological process | GO:0010528 | 9 | 4 | 16441 | 1675 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 8.883e-03 | -4.72 | positive regulation of fatty acid beta-oxidation | biological process | GO:0032000 | 9 | 4 | 16441 | 1675 |
IRS2,TWIST1,PLIN5,PPARA |
| 8.883e-03 | -4.72 | regulation of cell communication by electrical coupling involved in cardiac conduction | biological process | GO:1901844 | 9 | 4 | 16441 | 1675 |
CALM3,CALM2,PDE4D,CALM1 |
| 8.883e-03 | -4.72 | activation of anaphase-promoting complex activity | biological process | GO:0051488 | 9 | 4 | 16441 | 1675 |
PLK1,UBE2C,PTEN,CDC20 |
| 8.883e-03 | -4.72 | negative regulation of transposition | biological process | GO:0010529 | 9 | 4 | 16441 | 1675 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 8.883e-03 | -4.72 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | GO:0031657 | 9 | 4 | 16441 | 1675 |
PIM1,AKT1,PTEN,RGCC |
| 8.883e-03 | -4.72 | positive regulation of mitotic metaphase/anaphase transition | biological process | GO:0045842 | 9 | 4 | 16441 | 1675 |
PLK1,DLGAP5,PTEN,ESPL1 |
| 8.899e-03 | -4.72 | skin-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-malignant_melanoma-superficial_spreading | 31 | 8 | 17775 | 1757 |
NF2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2 |
| 8.899e-03 | -4.72 | central_nervous_system-temporal_lobe-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-ependymoma | 31 | 8 | 17775 | 1757 |
ZFYVE16,PTEN,MKRN3,RASA2,SYNE2,TP53,MORF4L2,PIKFYVE |
| 8.905e-03 | -4.72 | steroid hormone binding | molecular function | GO:1990239 | 5 | 3 | 16491 | 1673 |
ATP1A1,GPER1,NR3C1 |
| 8.918e-03 | -4.72 | PDGF | pfam domains | PF00341 | 9 | 4 | 16629 | 1696 |
PDGFA,PGF,PDGFC,PDGFB |
| 8.931e-03 | -4.72 | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | MSigDB lists | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | 657 | 84 | 17758 | 1761 |
CCNI,ADD1,GNPDA1,CRYM,PSME1,SNN,PJA2,ERP29,KBTBD11,CHPF,APLP2,ATP6V0B,EFR3A,DPYSL2,AKR1B1,ATRNL1,GOT1,IFIT1,MARCH2,MYRIP,GPX4,SEC61B,AKT1,STAU2,DRAP1,HSPA12A,NFE2L1,GLO1,ALCAM,OPTN,MAN2A2,MSL1,SLC25A4,PNPLA6,SERPINI1,ITPKA,LTA4H,COBL,MYL12B,CBX7,GRN,BIN1,CD99,LASP1,PINK1,SERPINE2,ENO2,PDIA3,PSMD10,COX6C,TRIB2,TIPRL,TSPAN7,SNTA1,CDK16,RIMS3,ATP5H,RUNDC3B,SORL1,FAM102A,TMBIM6,AHCY,NPTXR,ALDH2,RHOA,PSMB4,MPP1,NPC2,PSMA4,RASA1,GNAS,NUCB1,RPL12,SCG2,PRCP,UTP14C,SPINT2,TCEAL4,PGRMC1,DTX4,CABIN1,FHL1,ARPC2,RUSC1 |
| 8.940e-03 | -4.72 | cytoplasmic side of membrane | cellular component | GO:0098562 | 168 | 27 | 17570 | 1756 |
IQGAP1,RASA2,EZR,TEC,YES1,CACNB4,SPTB,GNA11,RASA1,GNAS,CDH1,JAK1,CDK16,PTEN,SNX18,CABP1,DLG1,ARRB1,DAB2IP,GEM,JAK3,TRAF5,TIAM1,SYK,GM2A,S100A6,ESYT2 |
| 8.961e-03 | -4.71 | liver development | biological process | GO:0001889 | 112 | 20 | 16441 | 1675 |
HES1,FOXM1,THRA,CAST,RPS6KA1,SOX9,AK4,ERBB2,ICMT,NPHP3,CCND1,E2F7,ONECUT1,CYP1A1,PIK3CA,ARF6,CITED2,E2F8,COBL,JARID2 |
| 8.961e-03 | -4.71 | cellular response to unfolded protein | biological process | GO:0034620 | 112 | 20 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,AMFR,DNAJC3,ERO1A,PDIA5,DNAJB11,DNAJB9,LMNA,CCND1,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 8.961e-03 | -4.71 | regulation of embryonic development | biological process | GO:0045995 | 112 | 20 | 16441 | 1675 |
HES1,TGIF1,CCSAP,OSR2,NPHP3,PRKACA,CDK1,DAG1,PPP2R3A,FZD7,SIX4,BMP7,PTK7,TRAF3IP1,TBX18,NKD1,WNT3A,OSR1,DVL2,GPR161 |
| 8.977e-03 | -4.71 | negative regulation of cytokine production | biological process | GO:0001818 | 212 | 33 | 16441 | 1675 |
DDX58,SIGIRR,LGR4,NLRX1,INPP5D,HERC5,NDRG2,CD274,TRIB2,GSTP1,FBLN1,RNF128,BCL6,CDH3,TWIST1,C10orf54,ITCH,RGCC,FURIN,PTGER4,EZR,CD83,BANK1,AXL,NMI,TRAF3IP1,NOD2,NLRC5,ARRB1,IFIH1,F2RL1,JAK3,NDFIP1 |
| 8.977e-03 | -4.71 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043281 | 212 | 33 | 16441 | 1675 |
CASP3,NKX3-1,RPS6KA1,DAP,RET,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,BAX,DAPK1,CDKN1B,EGLN3,WNT3A,CDKN2D,F2R,SIRT1,RHOA,AKT1,ACVR1C,PLAUR,CASP9,SLC11A2,POR,FAS,NGFRAP1,ARRB1,GPER1,MAP3K5,IFI6,XDH |
| 8.998e-03 | -4.71 | MODULE_75 | MSigDB lists | MODULE_75 | 394 | 54 | 17758 | 1761 |
GRN,IL15RA,NQO1,IL15,HLA-F,DNAJC3,EPS8,SELL,ERBB2,IL18,IL27RA,MGST2,SNN,SEPP1,PDGFB,ETS1,EMP2,IL18R1,LGALS3BP,HLA-A,PDGFA,CTGF,CYR61,CTSC,KCNN4,IL6ST,BCL6,DAPK1,TACSTD2,IFIT1,HLA-C,LAMP3,MX1,CD55,IFITM3,PTGER4,CR2,ARHGDIB,RUNX3,ALCAM,CDK5R1,EDNRA,FAS,CD83,MDK,HLA-B,SEMA4D,CSF1,P4HA2,NFKBIA,NR4A2,IRF7,GEM,AHR |
| 9.000e-03 | -4.71 | PLK1 signaling events | Pathway Interaction DB | plk1_pathway | 44 | 13 | 2227 | 331 |
PLK1,WEE1,RHOA,KIF20A,CDC20,NDC80,TUBG1,AURKA,BUB1,CENPE,CCNB1,BORA,CDK1 |
| 9.012e-03 | -4.71 | calcium activated phosphatidylcholine scrambling | biological process | GO:0061590 | 5 | 3 | 16441 | 1675 |
ANO9,ANO4,ANO6 |
| 9.012e-03 | -4.71 | mitotic centrosome separation | biological process | GO:0007100 | 5 | 3 | 16441 | 1675 |
AURKA,NDE1,KIF11 |
| 9.012e-03 | -4.71 | apolipoprotein A-I-mediated signaling pathway | biological process | GO:0038027 | 5 | 3 | 16441 | 1675 |
ITGAV,RHOA,ABCA1 |
| 9.012e-03 | -4.71 | nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | GO:0070431 | 5 | 3 | 16441 | 1675 |
RIPK2,NFKBIA,NOD2 |
| 9.012e-03 | -4.71 | positive regulation of cyclic-nucleotide phosphodiesterase activity | biological process | GO:0051343 | 5 | 3 | 16441 | 1675 |
CALM3,CALM2,CALM1 |
| 9.012e-03 | -4.71 | regulation of rubidium ion transport | biological process | GO:2000680 | 5 | 3 | 16441 | 1675 |
CAB39,STK39,CD63 |
| 9.012e-03 | -4.71 | response to corticotropin-releasing hormone | biological process | GO:0043435 | 5 | 3 | 16441 | 1675 |
NR4A2,NR4A1,NR4A3 |
| 9.012e-03 | -4.71 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GO:1901621 | 5 | 3 | 16441 | 1675 |
PRKACA,TRAF3IP1,GPR161 |
| 9.012e-03 | -4.71 | calcium activated galactosylceramide scrambling | biological process | GO:0061591 | 5 | 3 | 16441 | 1675 |
ANO9,ANO4,ANO6 |
| 9.012e-03 | -4.71 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | biological process | GO:0018401 | 5 | 3 | 16441 | 1675 |
EGLN3,P4HA2,EGLN1 |
| 9.012e-03 | -4.71 | cellular response to corticotropin-releasing hormone stimulus | biological process | GO:0071376 | 5 | 3 | 16441 | 1675 |
NR4A2,NR4A1,NR4A3 |
| 9.012e-03 | -4.71 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway | biological process | GO:0002484 | 5 | 3 | 16441 | 1675 |
HLA-B,HLA-C,HLA-A |
| 9.012e-03 | -4.71 | STAT protein import into nucleus | biological process | GO:0007262 | 5 | 3 | 16441 | 1675 |
HES1,JAK3,F2R |
| 9.012e-03 | -4.71 | calcium activated phospholipid scrambling | biological process | GO:0061588 | 5 | 3 | 16441 | 1675 |
ANO9,ANO4,ANO6 |
| 9.012e-03 | -4.71 | chorionic trophoblast cell differentiation | biological process | GO:0060718 | 5 | 3 | 16441 | 1675 |
E2F7,FZD5,E2F8 |
| 9.013e-03 | -4.71 | GNF2_CDKN1C | MSigDB lists | GNF2_CDKN1C | 25 | 7 | 17758 | 1761 |
GDF15,TIMP2,CDKN1C,CAPN6,ALPP,MAFF,SEMA3B |
| 9.013e-03 | -4.71 | ORGANELLE_LOCALIZATION | MSigDB lists | ORGANELLE_LOCALIZATION | 25 | 7 | 17758 | 1761 |
SUN2,NUSAP1,CENPE,AP1M2,SHROOM2,CDCA5,NIN |
| 9.013e-03 | -4.71 | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | MSigDB lists | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 25 | 7 | 17758 | 1761 |
COL18A1,GAA,IL13RA1,PRSS23,NQO1,NR3C1,PLAUR |
| 9.015e-03 | -4.71 | positive regulation of gene expression | biological process | GO:0010628 | 1690 | 201 | 16441 | 1675 |
LGR4,EPAS1,DNAJC3,HEXB,RET,IL18,MORF4L2,CAMK1D,CCNB1,PDGFB,ERP29,EPCAM,HSF2,RPS6KA2,CTGF,GRHL1,NPNT,ZFP36,IL31RA,MITF,FOSB,PASK,ELF5,IRF2,PIK3CD,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,EZR,TFAP2C,F12,LDB2,SAV1,ARF4,AHRR,PIAS3,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,FBLN1,PSIP1,LMNA,MECOM,ELF3,TFAP4,DAZAP1,ITGA3,CYR61,GATA2,MDFIC,MYDGF,WNT3A,NUP85,RIMS2,ELK3,MFI2,RGMB,SALL4,STAT4,PYM1,MYBL2,ELK1,TP53INP2,NFIB,ONECUT1,NCOA3,ETS2,PLPP3,SETD3,CSF1,NFKBIA,NLRC5,NR4A2,TOB1,RARG,TMEM173,KLF7,ARMCX3,GRHL2,UPF3B,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,SS18,CDH1,SP100,LMO4,CDH3,DAB2IP,TWIST1,EPB41L4B,NOTCH3,ETV4,MYT1,F2R,MED30,DVL2,CTH,SIRT1,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,ERBB2IP,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,TLE1,KLF5,NRG1,IRF7,GLIS3,ANXA3,PINK1,NKX3-1,TNRC6C,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,ITGB8,PTEN,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,MAPK11,CITED2,IQGAP3,TRIM62,SPRY2,NCOA2,NFE2L3,HES1,RHOA,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,EIF5A2,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,NR1D2,ACVRL1,NR4A3,ARRB1,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 9.018e-03 | -4.71 | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | MSigDB lists | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | 115 | 20 | 17758 | 1761 |
DDX58,MX1,LTBP1,CDK17,NF2,SERPINE2,XYLT1,ARL4C,ARHGDIB,TGFBR1,IL13RA1,RAB6A,DUSP4,DPYSL3,CALD1,PLK2,AOX1,SORL1,APOBEC3G,IFI6 |
| 9.018e-03 | -4.71 | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | 115 | 20 | 17758 | 1761 |
PLA2G4A,MYL9,RHOA,ARHGEF11,CALM1,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,ITPR1,PRKG1,CACNA1D,PLCB2 |
| 9.018e-03 | -4.71 | CHEBOTAEV_GR_TARGETS_DN | MSigDB lists | CHEBOTAEV_GR_TARGETS_DN | 115 | 20 | 17758 | 1761 |
PLA2G4A,CHSY3,MYL9,ATP8A1,S100A4,USP18,LRP4,PTGER4,VWA1,CACNB4,CA8,SH3KBP1,CRISPLD2,PDLIM3,ANKRD6,ZNF704,LIMCH1,SLC39A10,PKIA,IGDCC4 |
| 9.033e-03 | -4.71 | human chr5q15 | chromosome location | human chr5q15 | 26 | 6 | 26250 | 1887 |
ERAP1,MCTP1,ARSK,RGMB,CAST,ERAP2 |
| 9.035e-03 | -4.71 | JI_RESPONSE_TO_FSH_DN | MSigDB lists | JI_RESPONSE_TO_FSH_DN | 57 | 12 | 17758 | 1761 |
GNS,TOP2A,KIF5B,PACSIN2,JAK1,ADD1,ITGA6,TMBIM6,RAB6A,CCNF,ARF6,RANBP9 |
| 9.035e-03 | -4.71 | DASU_IL6_SIGNALING_UP | MSigDB lists | DASU_IL6_SIGNALING_UP | 57 | 12 | 17758 | 1761 |
TAPBP,ZFP36,HLA-F,COL6A1,TFAP2C,GEM,COL16A1,PTGES,MAFF,ATP2B1,IER3,CKS2 |
| 9.035e-03 | -4.71 | CCACACA,MIR-147 | MSigDB lists | CCACACA,MIR-147 | 57 | 12 | 17758 | 1761 |
ATP1A1,GPRC5B,CAPN6,NR3C1,RGS3,CYP2S1,CTDSPL,SLC44A1,TRIOBP,MAL2,TIPARP,KLF7 |
| 9.035e-03 | -4.71 | MODULE_199 | MSigDB lists | MODULE_199 | 57 | 12 | 17758 | 1761 |
FGFR2,PTK7,AXL,EPHA4,RYK,DAPK1,ERBB2,IL13RA1,ROR1,MERTK,LEPR,CDK5R1 |
| 9.035e-03 | -4.71 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | 57 | 12 | 17758 | 1761 |
CCND1,PDGFA,CASP3,SERPINA1,PQLC3,KCNN4,ITGA6,FUT8,CD9,FXYD5,RASA1,ACOT7 |
| 9.040e-03 | -4.71 | ABC1 | pfam domains | PF03109 | 5 | 3 | 16629 | 1696 |
ADCK5,ADCK3,ADCK2 |
| 9.040e-03 | -4.71 | Lamp | pfam domains | PF01299 | 5 | 3 | 16629 | 1696 |
LAMP2,LAMP1,LAMP3 |
| 9.044e-03 | -4.71 | basolateral plasma membrane | cellular component | GO:0016323 | 208 | 32 | 17570 | 1756 |
ST14,ITGA6,ERBB2,SLC1A3,PDGFB,EPCAM,ADORA1,CA2,ITGA3,KCNN4,DLG1,CNNM4,TRPC1,CLDN4,TACSTD2,ERBB3,DLG3,SLC12A2,ABCC1,EZR,SCRIB,ATP1B1,ERBB2IP,DAG1,ENPP1,ATP1A1,SLC4A4,ATP7B,NOD2,ARRB1,STK39,PROM2 |
| 9.053e-03 | -4.70 | cell cycle phase transition | biological process | GO:0044770 | 301 | 44 | 16441 | 1675 |
CCNE2,CEP70,FOXM1,PSME2,CIT,EPS8,PSMD10,PSME1,CCNB1,PRKACA,CDKN2C,CCND1,WEE1,E2F7,PSMD1,CNTRL,CEP78,NEK2,PLK4,TUBG1,CDKN1B,IQGAP3,CDKN2D,PLK1,PSMB4,MYBL2,PRKAR2B,PKMYT1,BORA,PSMA4,CDK1,OPTN,PRIM1,PLK2,CDCA5,ABCB1,AURKA,KLF11,CEP41,NDE1,CCNB2,UBE2C,PPP2R2D,MELK |
| 9.069e-03 | -4.70 | PID_AVB3_OPN_PATHWAY | MSigDB lists | PID_AVB3_OPN_PATHWAY | 31 | 8 | 17758 | 1761 |
RHOA,NFKBIA,PIK3R1,PIK3CA,ITGAV,FOS,BCAR1,SYK |
| 9.069e-03 | -4.70 | BURTON_ADIPOGENESIS_12 | MSigDB lists | BURTON_ADIPOGENESIS_12 | 31 | 8 | 17758 | 1761 |
MTM1,TMEM68,H1F0,IMPAD1,DNAJC3,BUB1,C3orf58,CYP1B1 |
| 9.069e-03 | -4.70 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | 31 | 8 | 17758 | 1761 |
RHOA,SEC61B,NR4A1,CD82,SAT1,FURIN,GSTP1,ESYT2 |
| 9.069e-03 | -4.70 | BIOCARTA_EGF_PATHWAY | MSigDB lists | BIOCARTA_EGF_PATHWAY | 31 | 8 | 17758 | 1761 |
PLCG1,JAK1,STAT4,PIK3R1,PIK3CA,ELK1,FOS,RASA1 |
| 9.070e-03 | -4.70 | Tetraspanin_EC2 | interpro domains | IPR008952 | 31 | 8 | 18293 | 1814 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN1,TSPAN7 |
| 9.070e-03 | -4.70 | Thioredoxin_domain | interpro domains | IPR013766 | 31 | 8 | 18293 | 1814 |
DNAJC10,TXN,TMX4,PDIA5,PDIA3,TXNDC11,PDIA6,PDIA4 |
| 9.071e-03 | -4.70 | transition metal ion binding | molecular function | GO:0046914 | 1395 | 168 | 16491 | 1673 |
UNKL,TRIM2,LMCD1,SYTL4,HDAC6,PJA2,CA8,BARD1,TRIM68,CYP1A1,ZCCHC12,PRICKLE3,SIVA1,MKRN3,CYP2S1,AOX1,MARCH2,RNF26,MYRIP,S100A13,APOBEC3G,RASGRP1,ERAP2,CYP1B1,THRB,PCGF5,TRIM8,ING1,CDA,LOXL2,RNF19B,ZFAND5,TP53I3,CYP4F3,POR,PIAS3,CXXC4,MAN2A2,TRIM9,ENPP1,NEIL1,P4HA2,PTER,LIMK1,ATP7B,BMP1,TRAF5,NR2C2,DDX58,LASP1,ZCCHC24,RABGGTA,MARCH8,CA2,ZNRF2,GATA2,LIMCH1,PIM1,ZMYM1,ZRANB1,MYLIP,CYP26B1,PMPCB,ZNF84,MFI2,GYLTL1B,RNF113A,JADE2,G2E3,DCP2,FECH,MMP15,NUDT16,P4HA3,S100A5,AGBL5,ZDHHC7,NR4A2,ZDBF2,DRP2,IFIH1,RARG,RNF146,KLF7,XDH,ADAMTS16,EGLN1,LMO7,RNF224,THRA,P3H2,TP53,MORC4,RNF182,FTH1,CYP39A1,CYP26A1,ZNF385B,APOBEC3B,APLP2,RNF220,ZNF75D,SETDB2,CYP4F11,LMO4,ZDHHC12,LHX6,ZDHHC23,VAT1,EGLN3,MYT1,NR2C1,CPD,SEC23A,APOBEC3D,UTRN,SLC11A2,GLO1,PYGO1,AMZ2,JADE1,IDE,PDLIM3,MMP17,PEX2,ADAMTS14,CYP2U1,LTA4H,NR3C2,ZMAT1,MAN2B2,FBLIM1,ERI2,APOBEC3H,ZDHHC21,DTX3L,PHF7,RNF128,ALPP,ZFAND4,TRIM21,ADAM15,TRIM62,S100A6,PHF20L1,ADAMTS2,LONRF3,NR3C1,NR4A1,AMFR,RC3H2,PPARA,PRICKLE1,BLVRA,NEURL1B,RNPEP,GALNT3,PLOD2,TRIM69,NR1D2,ZNF214,DTX4,NR4A3,ERAP1,FHL1,PLOD3,ZMIZ1,TLL2 |
| 9.115e-03 | -4.70 | V$PAX4_02 | MSigDB lists | V$PAX4_02 | 226 | 34 | 17758 | 1761 |
CPEB4,CAST,TSC22D3,MIER3,TGFBR1,RAB6A,SYTL2,FOXP2,RALGPS2,RNF128,ZDHHC12,MITF,DIXDC1,TACSTD2,BTBD3,PLEKHA6,ELK3,TBC1D8B,SAT1,MBNL3,RGAG1,LDB2,PPP1R14C,NFIX,ARHGAP24,PITX2,SLC4A4,ITGA7,ARRB1,ZMIZ1,SEMA3A,TOB1,HOXC13,JARID2 |
| 9.124e-03 | -4.70 | MODULE_241 | MSigDB lists | MODULE_241 | 71 | 14 | 17758 | 1761 |
MYL9,WASF3,TRIP10,FOXM1,SEMA4D,SECTM1,NRG1,GDF15,ATP1B1,PIEZO1,LGMN,ETS1,LGALS3BP,IER3 |
| 9.124e-03 | -4.70 | GNF2_SPTB | MSigDB lists | GNF2_SPTB | 71 | 14 | 17758 | 1761 |
FECH,MARCH8,GCLM,CA2,ERMAP,H1F0,HEBP1,MPP1,BLVRB,EIF2AK1,MINPP1,SPTB,TRAK2,RAD23A |
| 9.124e-03 | -4.70 | GNF2_ANK1 | MSigDB lists | GNF2_ANK1 | 71 | 14 | 17758 | 1761 |
MARCH8,FECH,GCLM,CA2,ERMAP,H1F0,HEBP1,MPP1,BLVRB,EIF2AK1,MINPP1,SPTB,TRAK2,RAD23A |
| 9.124e-03 | -4.70 | KEGG_MELANOMA | MSigDB lists | KEGG_MELANOMA | 71 | 14 | 17758 | 1761 |
CCND1,PDGFA,PDGFC,IGF1R,AKT1,CDH1,PTEN,MITF,PIK3R1,PIK3CA,TP53,PIK3CD,PDGFB,FGF19 |
| 9.249e-03 | -4.68 | hemopoiesis | biological process | GO:0030097 | 520 | 70 | 16441 | 1675 |
CASP3,ADD1,HOXB7,EPAS1,IL15,THRA,TP53,PDGFB,TNFSF9,SPTB,PLCG2,MITF,IL31RA,TMEM143,BCL6,RTKN2,PIK3CD,SNX10,TIPARP,OSTM1,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,HOXA9,AXL,PTBP3,DHTKD1,F2RL1,RUNX2,TNRC6C,CDKN1C,BVES,HERC6,MERTK,IL18R1,MECOM,SGPL1,HDAC9,CD109,TOP2A,GATA2,BAX,WNT3A,SYK,FARP2,RHOA,RC3H2,PIK3R1,TTC7A,EIF2AK1,RUNX3,FAS,FECH,ONECUT1,TWSG1,FGFR2,DHRS2,CSF1,LRRK1,FZD5,SLC25A38,JAK3,MELK |
| 9.287e-03 | -4.68 | Nuclear Receptors | WikiPathways | WP170 | 38 | 10 | 4455 | 516 |
THRB,NR1D2,NR3C1,NR4A1,THRA,PPARA,NR4A2,ROR1,RARG,NR2C2 |
| 9.333e-03 | -4.67 | early endosome membrane | cellular component | GO:0031901 | 107 | 19 | 17570 | 1756 |
CLCN3,ATP9A,HLA-E,HLA-F,EPHA4,FAM21C,HLA-A,ZFYVE9,MARCH8,ZFYVE16,HLA-B,SLC9A6,KIAA0319,SNX16,HLA-C,WNT3A,PIKFYVE,FZD5,EHD1 |
| 9.333e-03 | -4.67 | dendritic spine | cellular component | GO:0043197 | 107 | 19 | 17570 | 1756 |
EPHA4,GRIN1,FBXO2,PRKAR2B,SLC1A3,ARF4,GRM5,CDK5R1,ADORA1,PTEN,ANKS1B,SIPA1L1,ARRB1,CTTN,GPER1,RGS14,ITPKA,NRGN,LZTS1 |
| 9.336e-03 | -4.67 | Pept_C1 | smart domains | SM00645 | 13 | 5 | 9131 | 997 |
CTSL,CTSZ,TINAGL1,CTSC,CTSV |
| 9.337e-03 | -4.67 | regulation of cell cycle phase transition | biological process | GO:1901987 | 277 | 41 | 16441 | 1675 |
DLGAP5,PSME2,CUL4B,CTDSPL,TP53,PSMD10,PSME1,CCNB1,FANCI,IER3,SUSD2,CCND1,E2F7,CYP1A1,PSMD1,PTEN,DACT1,KIF14,CDKN1B,BUB1,PIM1,CTDSP2,PLK1,AKT1,PSMB4,CDC20,RGCC,PRKCQ,ANLN,PSMA4,CDK1,JADE1,TJP3,CDCA5,FAM83D,OVOL1,FHL1,CENPE,UBE2C,ESPL1,PKIA |
| 9.355e-03 | -4.67 | regulation of protein exit from endoplasmic reticulum | biological process | GO:0070861 | 19 | 6 | 16441 | 1675 |
SORL1,YOD1,ERLEC1,BCAP31,TMEM30A,UBE2J1 |
| 9.355e-03 | -4.67 | positive regulation of protein autophosphorylation | biological process | GO:0031954 | 19 | 6 | 16441 | 1675 |
CALM3,CALM2,PDGFA,PDGFB,CALM1,RAP2C |
| 9.378e-03 | -4.67 | WANG_TUMOR_INVASIVENESS_DN | MSigDB lists | WANG_TUMOR_INVASIVENESS_DN | 202 | 31 | 17758 | 1761 |
CCNI,DLGAP5,IQGAP1,HABP4,FURIN,LITAF,ATP1B1,DHRS3,NFIB,ABCD4,APLP2,CDH1,H1F0,HNRNPH2,CORO1C,KBTBD2,COL6A1,DLG1,CD9,RYK,ARVCF,SLC27A1,MDFIC,EFNA5,STK39,ERBB3,UBE2C,PPP2R2D,GM2A,XDH,ABCG1 |
| 9.391e-03 | -4.67 | Assembly of collagen fibrils and other multimeric structures | REACTOME pathways | R-HSA-2022090 | 54 | 12 | 8202 | 867 |
CTSL,COL6A2,PCOLCE,ITGA6,CTSV,COL6A1,BMP1,COL18A1,COL4A5,COL7A1,LOXL2,TLL2 |
| 9.403e-03 | -4.67 | metal ion binding | molecular function | GO:0046872 | 4013 | 447 | 16491 | 1673 |
ACACB,HSPG2,SLC25A13,ATP8A1,RET,CACNA2D2,LACTB2,SYTL4,PJA2,CA8,BARD1,LTBP3,ZNF275,NCS1,EPDR1,CALM2,WEE1,CYP1A1,ZNF823,STIM1,PRICKLE3,ZFP36,CABP1,CYP2S1,KLF3,STEAP2,AOX1,MARCH2,ZBTB18,RNF26,SMYD5,TIPARP,APOBEC3G,ERAP2,METAP2,ACVR1C,CDA,LOXL2,PIF1,GALNT7,MCFD2,RNF19B,ZFAND5,TP53I3,CYP4F3,POR,PRIM1,PIAS3,ENPP1,PLCG1,GDE1,PTER,LIMK1,GNPTAB,ATP7B,NKD1,PRDM5,BMP1,AGFG2,TRAF5,FGD1,DDX58,NUAK1,ITGA6,DGKQ,CALB2,MTL5,S100A2,HPCAL4,PRRG4,RABGGTA,MECOM,MARCH8,GNS,ITGA3,ZNRF2,MEGF8,NEK2,CADPS2,CACNA1D,ZMYM1,PIKFYVE,MAST4,DGKG,MYLIP,SYTL3,RIMS2,PMPCB,ZNF84,MFI2,TBC1D8B,SALL4,CALM1,ATP8B3,ANTXR1,JADE2,GNA11,DCP2,CYB5A,DGKH,MMP15,TIMM8A,MATN2,S100A5,AGBL5,FGD6,PCDH19,NR4A2,DRP2,MAP3K5,IFIH1,ZNF502,XDH,ADAMTS16,EGLN1,EHD1,PLA2G4A,RNF224,REPS2,S100A11,GALNT12,THRA,RPS6KA1,IQGAP1,ATP2C2,TESK2,RNF182,FTH1,DDR1,CYP39A1,REPS1,ZFYVE9,ZNF385B,APOBEC3B,RCN1,APLP2,ACAP2,RNF220,ZNF75D,CDH1,ENPP5,PDE4D,MYT1,NR2C1,ENPP4,SEC23A,APOBEC3D,UTRN,PRKCQ,SLC11A2,ATP1B1,PYGO1,PKMYT1,XRCC6BP1,ATP10D,ZNF618,SP4,ZNF469,NIN,AMZ2,PDLIM3,NGFRAP1,STK26,ZNF704,EFCAB14,TRABD2A,KLF5,NR3C2,MAPK12,ATP9A,EFHD2,CYB561,APOBEC3H,NUCB2,DTX3L,PHF7,RNF128,ARSG,PTEN,MGAT4A,FAM20B,ZFAND4,ATP8B1,PLEKHF1,ADAM15,CNOT6L,NPTXR,TRIM62,S100A6,ADAMTS2,ARAP2,ARHGEF28,PLSCR1,LONRF3,ZC3H11A,RAPGEF2,GRIN1,FURIN,ZKSCAN2,BLVRA,NEURL1B,AIF1L,ARSK,GALNT3,CDK5RAP1,NUCB1,TIMP3,PLOD2,ACVRL1,NR1D2,SYT7,NR4A3,PGM2L1,ERAP1,ITGAV,FHL1,LRRK1,OSR1,ARSB,CYBRD1,MELK,ESYT2,TLL2,MYL9,UNKL,LTBP1,NMRK1,TRIM2,CNOT8,LMCD1,NENF,MGAT5B,HDAC6,DNER,TRIM68,PLS3,CHPF,ZFYVE16,RPS6KA2,NPNT,ZCCHC12,SIVA1,IMPAD1,MKRN3,PAPL,MYRIP,DDX59,S100A13,RASGRP1,SP5,CYP1B1,ZNF462,THRB,PCGF5,KCNIP3,ING1,MCTP1,TRIM8,CELSR2,IDH1,ZBTB7B,RHEB,KDM4D,DZIP1L,TRIM9,MAN2A2,CXXC4,PLCH1,NEIL1,ZNF114,KLF12,P4HA2,ZNF367,ZNF165,ADIPOR1,SP6,KLF11,MYL12B,CAPN1,CPPED1,NR2C2,PRKAA2,LASP1,PARP12,LMTK3,ARAP3,ZNF395,ZCCHC24,RASA2,CALM3,TEC,B4GALT4,PHLPP1,FBLN1,ZNF432,CA2,GATA2,FRAS1,LIMCH1,PIM1,ZRANB1,PLCB2,CYP26B1,CHSY3,PCDH1,TESK1,ZNF320,MGAT4B,GYLTL1B,PDE5A,RNF113A,NUBP1,STEAP1,AMDHD1,G2E3,CDK5R1,RASGRP2,FECH,GNAS,NUDT16,PHLPP2,ITGA7,CGREF1,PRPS2,P4HA3,ZDHHC7,EGFL7,YOD1,LTBP2,ZDBF2,RARG,RNF146,KLF7,LMO7,SLC25A24,UGP2,P3H2,CTDSPL,TP53,MORC4,COL18A1,OSR2,CYP26A1,SYTL2,ZNF687,SETDB2,CYP4F11,LMO4,ZDHHC12,LHX6,SRR,BCL6,ZDHHC23,VAT1,CDH3,ECE1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,CHP1,SULF2,MAP3K3,CPD,SIRT1,ZNF525,GCA,TIMP2,FIGNL1,S100A4,ACO1,GLO1,MYL12A,MAP3K6,DAG1,ATP13A2,JADE1,DUOX1,IDE,ATP1A1,MMP17,STK38,PEX2,ADAMTS14,OVOL1,ANXA9,SYT13,CYP2U1,LTA4H,AIFM3,ZNF701,GLIS3,ZMAT1,MAN2B2,ANXA3,FBLIM1,PINK1,ENO2,CDH22,CIT,LRP4,GNE,ERI2,TGFBR1,GTF3A,NRP2,PPP2R3A,HDAC9,ZDHHC21,IRF2BPL,TOP2A,FOXP2,TAF1B,MLPH,ALPP,GALNS,TRIM21,KLF9,ATP2B1,MYO5A,FAH,PHF20L1,PGM1,FBLN5,NR3C1,NR4A1,GCLC,AMFR,RC3H2,PPARA,MBNL3,OGDHL,PRICKLE1,RNPEP,DGKE,ENDOD1,SWAP70,FAT4,TRIM69,ZNF214,DTX4,PPP2R3C,GEM,PLOD3,ZMIZ1,ZBTB33 |
| 9.406e-03 | -4.67 | GLHYDRLASE27 | prints domains | PR00740 | 2 | 2 | 4759 | 462 |
GLA,NAGA |
| 9.422e-03 | -4.66 | alcohol metabolic process | biological process | GO:0006066 | 343 | 49 | 16441 | 1675 |
PLA2G4A,PRKAA2,INPP5D,CALM3,ISYNA1,LPIN3,DHRS3,CYP39A1,LBR,CDS1,CALM2,APLP2,CYP1A1,PTEN,IMPAD1,ALDH1A3,PLCG2,SLC44A1,AKR1B1,SLC44A2,SORL1,ALDH7A1,GOT1,MINPP1,LGMN,PLCB2,ALDH3A2,CYP1B1,ALDH2,CYB5R2,CALM1,NPC2,SPTLC2,PCTP,LEPR,GPLD1,FECH,PLCG1,ALDH3B1,PLCH1,PRKAG2,DBI,INPP4B,PNPLA6,SLC27A1,ITPKA,ABCA1,APOL2,ABCG1 |
| 9.431e-03 | -4.66 | DE_YY1_TARGETS_DN | MSigDB lists | DE_YY1_TARGETS_DN | 93 | 17 | 17758 | 1761 |
EPAS1,TACC1,EPS8,ERBB2IP,RAB6A,BARD1,CDK1,RASA1,FAS,RBL1,PTEN,CALD1,ERAP1,ITGAV,TAGLN2,MPHOSPH9,SOCS5 |
| 9.431e-03 | -4.66 | MODULE_174 | MSigDB lists | MODULE_174 | 93 | 17 | 17758 | 1761 |
MYL9,WASF3,TRIP10,FOXM1,FXYD3,GDF15,ATP1B1,ETS1,LGALS3BP,IER3,SEMA4D,SECTM1,NRG1,PIEZO1,DRP2,LGMN,TOB1 |
| 9.431e-03 | -4.66 | GSE14308_TH2_VS_TH1_DN | MSigDB lists | GSE14308_TH2_VS_TH1_DN | 194 | 30 | 17758 | 1761 |
SUSD3,B3GNT2,FAM92A1,DNAJC3,SEPT6,EPS8,TP53,C5orf30,FAM133B,ARSK,GNA11,DGKH,SS18,PLCH1,PLCG1,NEIL1,SESN3,JAK1,RBL1,ITGA7,OSBPL3,BCL6,ZNF704,ERAP1,IRF7,ALDH7A1,C10orf54,ARF6,CITED2,KLF7 |
| 9.431e-03 | -4.66 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | 194 | 30 | 17758 | 1761 |
ARMCX3,UGP2,CAST,AMFR,TMX4,HEXB,FURIN,SPATA13,FTH1,GPSM2,FNDC3A,FRMD4B,SGPL1,ITGA3,CTSC,PLOD2,TMEM30A,TSPAN6,MADD,PAPSS1,TOX2,N4BP3,SGK1,TNFRSF12A,GEM,RCAN3,SERPINB1,ALDH3A2,TLE6,RBMS2 |
| 9.431e-03 | -4.66 | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | 194 | 30 | 17758 | 1761 |
CCNE2,PCGF5,USP18,TAP1,ARFGEF1,IL18,IFIT3,CD40,CASP4,SP4,STX3,ABR,IER3,AHRR,GABRD,ENPP1,MDM1,SWAP70,CTSC,RBL1,TIMM8A,CSF1,TPST1,TRIM21,LTBP2,PDIA6,SERPINB1,SMAGP,CCDC88A,ABCC1 |
| 9.431e-03 | -4.66 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | 194 | 30 | 17758 | 1761 |
PMPCB,TTC39B,NFKBIE,PLSCR1,TRIP10,NR3C1,STAT4,RASA2,ARFGEF1,NOTUM,ZBTB7B,SPTLC2,LGALS3BP,SP4,NR1D2,WFS1,RRBP1,KLF3,SGK3,AOX1,TRIM21,CDKN1B,GLA,MAL2,NPTXR,SERPINB1,TOB1,CTDSP2,SMAGP,STARD3NL |
| 9.438e-03 | -4.66 | Histidine metabolism | KEGG pathways | hsa00340 | 23 | 7 | 6908 | 758 |
ALDH7A1,ALDH3B1,ALDH2,AMDHD1,ALDH3A2,HAL,ALDH1A3 |
| 9.438e-03 | -4.66 | Histidine metabolism | KEGG pathways | ko00340 | 23 | 7 | 6908 | 758 |
ALDH7A1,ALDH3B1,ALDH2,AMDHD1,ALDH3A2,HAL,ALDH1A3 |
| 9.451e-03 | -4.66 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | 170 | 27 | 17758 | 1761 |
EPB41L5,DOCK4,PPIF,THRB,SEC61B,TBC1D1,BCL9,DCAF7,PDIA5,NFE2L1,MIER3,ARFRP1,SLC1A3,ETS1,RNF19B,CD83,RAD23A,MAPKAPK2,ARHGEF19,PIK3AP1,NR4A3,TFAP2A,DTX4,ANKRD12,GLA,ACSL4,MCCC2 |
| 9.463e-03 | -4.66 | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | 186 | 29 | 17758 | 1761 |
TIMP2,ARAP3,KIF20A,CPEB4,HJURP,TACC1,MPP1,BLVRB,NDC80,CCDC34,RNF182,MRAS,PIF1,LHFPL2,LBR,ARHGEF26,CYP26A1,OPTN,IRS2,GNB5,UEVLD,KIF14,SGK3,NETO2,DTX4,ARRB1,PLEKHF1,TINAGL1,EHD1 |
| 9.463e-03 | -4.66 | P53_DN.V1_DN | MSigDB lists | P53_DN.V1_DN | 186 | 29 | 17758 | 1761 |
PLA2G4A,DDB2,FBLN5,NR4A1,STAT4,HSPA12A,RGS20,RUNX3,CTSZ,KBTBD11,HOXB2,TNFSF9,TSPAN7,NRP2,FRMD4B,FAS,SOCS3,ZFYVE16,CA2,CDH1,GPRC5B,MITF,BAX,NR4A3,AKR1B1,SGK1,IGFBP2,L1CAM,MYO5A |
| 9.463e-03 | -4.66 | GSE17721_CTRL_VS_POLYIC_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_0.5H_BMDM_UP | 186 | 29 | 17758 | 1761 |
MPP1,LRP4,NUB1,FAM134A,C6orf106,EFHD2,KIF13A,GRK6,NUCB2,ANLN,IDH1,PHLDA1,LBR,BCAP31,ARF4,LRRC42,PGF,CYP1A1,JAK1,CDK16,NAT1,PAPSS1,FAM20B,PHTF1,NEK2,FAM102A,CITED2,CPEB2,KDELR1 |
| 9.463e-03 | -4.66 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | 186 | 29 | 17758 | 1761 |
ZNF462,RIPK2,FAM81A,FAM101B,DENND2D,CASP4,DNAJB9,IRS2,OTUD1,BANK1,RNF220,ADORA1,PIK3AP1,FOSB,LRIG1,NETO2,INPP4B,PGM2L1,SGK1,DUSP10,NR4A2,NTN4,KLF9,PIM1,ST3GAL1,MYLIP,C9orf72,IGDCC4,CTH |
| 9.463e-03 | -4.66 | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDM_DN | 186 | 29 | 17758 | 1761 |
ARHGEF3,ELK3,PARP12,AASS,ZC3H11A,SNTB2,AMFR,ACTR8,CNOT8,NUB1,PDIA5,ARFGEF1,PSMD10,MCFD2,ZBTB7B,PSMA4,VPS26A,ATP6V0B,CDKN2AIPNL,ZDHHC12,XYLT2,PAPSS1,CD9,ECI2,PPP2R3C,ITGAV,NDE1,UBE2C,RASGRP1 |
| 9.463e-03 | -4.66 | GSE27786_LSK_VS_NKCELL_DN | MSigDB lists | GSE27786_LSK_VS_NKCELL_DN | 186 | 29 | 17758 | 1761 |
DDX58,SUN2,HECA,SORT1,TRIM8,CITED4,CPEB4,DNAJC3,HEXB,FZD7,VPS26A,RBM47,RINL,TRIM69,AXL,NFKBIA,AIM1,RRBP1,KLF3,NLRC5,AKR1B1,AGFG2,CCDC82,ABCD1,RELL1,ARF6,OSR1,ESYT2,GCNT1 |
| 9.463e-03 | -4.66 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_UP | 186 | 29 | 17758 | 1761 |
TM2D2,AVPI1,DNAJC3,LPGAT1,NDUFA4,GGH,PRKRA,IDH1,CYB5A,NIN,TMEM63A,KLHL2,TIMM8A,PEX2,N4BP3,SLC44A1,FAM110C,AGBL5,ECI2,EIF4EBP2,MRPS28,MANF,RNF26,LTA4H,TRAM1,PRR15,S100A6,ABCC1,WBP5 |
| 9.463e-03 | -4.66 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | 186 | 29 | 17758 | 1761 |
CCNI,FAM169A,ITCH,OXR1,FAM134A,CCDC34,PSME1,NPC2,SNX12,VPS26A,MESDC2,SS18,NUDT16,SCARB2,DDOST,SNX18,CTSC,SLC16A6,AMMECR1,MATN2,ITPR1,EXOC8,PIK3CA,ERAP1,MDFIC,TACSTD2,RNF26,CDKN2D,NRBP1 |
| 9.463e-03 | -4.66 | GSE27786_LIN_NEG_VS_BCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_BCELL_UP | 186 | 29 | 17758 | 1761 |
MTM1,SLC25A24,CITED4,SERPINE2,PTPN9,MRS2,ASB9,ERI2,CCDC34,AK4,NENF,CCNF,BORA,MNS1,OPTN,ELF3,SOX13,AP1AR,ACADSB,RBL1,IL6ST,DBI,ECI2,RPN2,MLKL,PIK3CD,GLA,WDR62,TBC1D4 |
| 9.471e-03 | -4.66 | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | MSigDB lists | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 178 | 28 | 17758 | 1761 |
SEC23A,B3GNT7,B3GNT2,GALNT12,PLAUR,EIF5A2,MGAT4B,FURIN,C1GALT1C1,PDIA3,GALNT7,MCFD2,B4GALT4,ARSK,GALNT3,MUC16,DDOST,ARSG,DOLPP1,MGAT4A,ALG13,FUT8,RPN2,LMAN1,ARSB,ST3GAL1,MGAT5,GCNT1 |
| 9.471e-03 | -4.66 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | 178 | 28 | 17758 | 1761 |
TXN,SPC25,PBK,PLAUR,XYLT1,EPHA4,SDC4,UBE2A,CR2,NDUFA4,IL18,PDK3,MNS1,TOP2A,PQLC2,UAP1,TIMM8A,PLOD2,PLK2,SH3BP4,TACSTD2,EPB41L4A,PTPRE,TRAM1,E2F8,COL16A1,ERAP2,NR2C2 |
| 9.471e-03 | -4.66 | KEGG_ENDOCYTOSIS | MSigDB lists | KEGG_ENDOCYTOSIS | 178 | 28 | 17758 | 1761 |
ARAP2,ARAP3,HLA-E,HLA-F,ITCH,RET,GRK6,ADRBK2,SH3KBP1,HLA-A,EPN3,HLA-B,ACAP2,IGF1R,ADRBK1,RAB11FIP2,FGFR2,DNM1L,RAB11FIP1,ARRB1,WWP1,ERBB3,PLD1,HLA-C,PIKFYVE,ARF6,F2R,EHD1 |
| 9.514e-03 | -4.66 | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | 108 | 19 | 17758 | 1761 |
ZNF462,ZMAT1,TM2D2,FAM92A1,FOXM1,CAST,CORO2A,TMX4,PIK3R1,PBX3,PRKCQ,TGFBR1,BEX2,STX3,IGF1R,MITF,DAB2IP,PLD1,TBC1D4 |
| 9.521e-03 | -4.65 | AMPK signaling | WikiPathways | WP1403 | 68 | 15 | 4455 | 516 |
PRKAA2,ACACB,SLC2A4,PRKAG2,AKT1,CAMKK1,PIK3R1,TP53,PIK3CA,STRADB,CAB39,ADIPOR1,PIK3CD,CCNB1,LEPR |
| 9.524e-03 | -4.65 | astrocytoma_Grade_III | COSMIC cancer mutations | astrocytoma_Grade_III | 1611 | 187 | 17775 | 1757 |
LTBP1,KLK10,SLC25A13,TMEM41B,HEXB,RET,ARFGEF1,NRG2,LYNX1,SYTL4,PLXNA1,FAM101B,DNER,SLC9A7,CDKN2C,HSF2,MUC4,LRRC6,STIM1,ARHGEF37,IQCE,OSBPL3,CYP2S1,TSPAN6,SLC44A1,AOX1,TMEM143,PIK3CA,TUBG1,ATRNL1,IRF2,NTN4,TLN2,MYRIP,NEB,MCTP1,NBPF3,MTRF1L,CR2,LDB2,IDH1,ADRBK2,COL12A1,AHRR,MAN2A2,ANKRD10,PLK2,ATP7B,NFKBIZ,PIEZO1,RELL1,TANC2,CPPED1,SCN5A,FRMD4A,TBC1D1,PYROXD2,MTL5,CNTNAP2,SAMD9,TNS3,DOPEY2,RALGPS2,IGF1R,PRKG1,MAP3K9,CADPS2,CACNA1D,LRIF1,SLC12A2,ABCC1,IGSF3,TRAK2,GFPT1,CHSY3,HPS3,MFI2,TBC1D8B,MICB,GNA11,SOX13,GNAS,BCAR3,XKRX,CACHD1,AP1AR,PVRL2,PRPS2,ITPR1,PITPNA,DRP2,MAP3K5,SHROOM2,SEMA3A,XDH,DOCK9,CCNE2,PLA2G4A,NCKAP5,SPRED1,NF2,REPS2,IL15,IQGAP1,TP53,ERBB2,FTH1,GRK6,PHLDA1,CYP39A1,ZFYVE9,ZNF385B,CDS1,RAD23A,MUC16,SP100,FRYL,CDKN1B,RTKN2,NR2C1,SCN3A,TMTC1,SEC23A,ZNF525,AKT1,PTPRU,UTRN,ASB13,DOCK5,FZD7,CMTM7,PTPRJ,IDE,ATP1A1,SHROOM3,CDK19,SLC27A1,EFNA5,SYT13,NR3C2,COBL,NDST3,DENND5B,CDH22,BLVRB,OSGIN2,HERC5,TGFBR1,NUCB2,DSE,FAM167A,PARM1,SLC9A2,MDM1,ADRBK1,SLC27A6,ANKS1B,PTEN,MGAT4A,GTF2F2,ERBB3,TAGLN2,IQGAP3,GCNT1,RASGRF1,PDGFC,FAM160A1,ASPM,RC3H2,PIK3R1,PPARA,MBNL3,DIAPH2,MAML2,SNTB1,CD83,GPLD1,DCTN6,ENDOD1,FAT4,ABCB1,PPM1H,CLIP4,GRIN2D,TBC1D4,ARSB,TLL2 |
| 9.570e-03 | -4.65 | ACB_1 | prosite domains | PS00880 | 5 | 3 | 11866 | 1235 |
ACBD5,ECI2,DBI |
| 9.577e-03 | -4.65 | PDGF_2 | prosite domains | PS50278 | 9 | 4 | 11866 | 1235 |
PDGFA,PGF,PDGFC,PDGFB |
| 9.593e-03 | -4.65 | JUN (jun proto-oncogene) | protein interactions | 3725 | 217 | 35 | 16036 | 1726 |
RUNX2,EPAS1,GGA1,TSC22D3,ETS1,ELF3,HDAC9,M6PR,TOP2A,APLP2,RPS6KA2,GATA2,GTF2F2,BCL6,MAPK11,ETV4,NCOA2,SIRT1,TGIF1,NR3C1,ITCH,STAT4,PLEKHO1,CASP9,NFE2L1,FOS,MAPK8IP1,NCOA3,ETS2,HOXA9,ARRB1,HDAC1,HMGA1,SOX8,PPP2R2D |
| 9.601e-03 | -4.65 | CTSA (cathepsin A) | protein interactions | 5476 | 29 | 8 | 16036 | 1726 |
CTNNBIP1,LAMP2,PVRL4,PLAUR,DNAJB2,CTSA,FBXO6,OAT |
| 9.601e-03 | -4.65 | MAPKAPK5 (mitogen-activated protein kinase-activated protein kinase 5) | protein interactions | 8550 | 29 | 8 | 16036 | 1726 |
MAPKAPK2,PLA2G4A,MBP,TP53,CDCA8,MAPK11,HSPB1,MAPK12 |
| 9.605e-03 | -4.65 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | MSigDB lists | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | 44 | 10 | 17758 | 1761 |
ADD1,WIPI1,DNAJC3,WFS1,PDIA5,DNAJB11,PDIA6,CTDSP2,DNAJB9,LMNA |
| 9.605e-03 | -4.65 | V$HOX13_01 | MSigDB lists | V$HOX13_01 | 44 | 10 | 17758 | 1761 |
CCND1,TRIM8,CDK16,CALD1,LMO4,YES1,UNC5B,NDFIP1,GPR161,NEO1 |
| 9.605e-03 | -4.65 | BIOCARTA_TCR_PATHWAY | MSigDB lists | BIOCARTA_TCR_PATHWAY | 44 | 10 | 17758 | 1761 |
CALM2,PLCG1,CALM1,NFKBIA,PIK3R1,PIK3CA,CALM3,ELK1,FOS,RASA1 |
| 9.605e-03 | -4.65 | HALLMARK_APICAL_SURFACE | MSigDB lists | HALLMARK_APICAL_SURFACE | 44 | 10 | 17758 | 1761 |
SLC2A4,LYPD3,PLAUR,AIM1,ATP8B1,EFNA5,EPHB4,HSPB1,SHROOM2,SULF2 |
| 9.606e-03 | -4.65 | Kinesin_motor_dom | interpro domains | IPR001752 | 44 | 10 | 18293 | 1814 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 9.613e-03 | -4.64 | JIANG_VHL_TARGETS | MSigDB lists | JIANG_VHL_TARGETS | 131 | 22 | 17758 | 1761 |
LAMP1,ENO2,ZNF395,TRIP10,RPS6KA1,NFE2L1,C6orf106,GTF2A2,HDAC6,MRPS36,RANBP9,IRF2BPL,SCARB2,SS18,ARTN,KBTBD2,UACA,GM2A,CAPN1,CKAP4,KDELR1,WBP5 |
| 9.619e-03 | -4.64 | glycogen metabolic process | biological process | GO:0005977 | 56 | 12 | 16441 | 1675 |
CALM2,GAA,PGM1,PRKAG2,PPP1R2,UGP2,AKT1,IL6ST,CALM1,CALM3,PGM2L1,PHKA2 |
| 9.727e-03 | -4.63 | positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903052 | 166 | 27 | 16441 | 1675 |
PLK1,DLGAP5,PSMB4,AKT1,DNAJB2,GCLC,PSME2,CDC20,NUB1,PRICKLE1,PSMD10,PSME1,TRIB2,CCNB1,RNF19B,PSMA4,CDK1,BCAP31,PSMD1,CTSC,PTEN,PLK2,AURKA,DAB2IP,UBE2C,ESPL1,SOCS5 |
| 9.752e-03 | -4.63 | FU | smart domains | SM00261 | 18 | 6 | 9131 | 997 |
ERBB2,ERBB3,IGF1R,FRAS1,PCSK5,FURIN |
| 9.764e-03 | -4.63 | negative regulation of leukocyte apoptotic process | biological process | GO:2000107 | 43 | 10 | 16441 | 1675 |
IRS2,TSC22D3,AXL,BCL6,NOD2,PRKCQ,IRF7,SLC39A10,JAK3,MERTK |
| 9.772e-03 | -4.63 | protein kinase A catalytic subunit binding | molecular function | GO:0034236 | 14 | 5 | 16491 | 1673 |
EZR,PRKAR2B,PJA2,SOX9,PKIA |
| 9.772e-03 | -4.63 | thioesterase binding | molecular function | GO:0031996 | 14 | 5 | 16491 | 1673 |
CALM3,CALM2,ARF6,TRAF5,CALM1 |
| 9.790e-03 | -4.63 | NGUYEN_NOTCH1_TARGETS_DN | MSigDB lists | NGUYEN_NOTCH1_TARGETS_DN | 86 | 16 | 17758 | 1761 |
PPIF,CCNI,EPHA4,TP53,PBX3,COL7A1,FNDC3A,SLC20A1,ETS2,IGF1R,CYR61,TFAP2A,KLF5,TIPARP,SLC12A2,SMYD5 |
| 9.803e-03 | -4.63 | EPH-Ephrin signaling | REACTOME pathways | R-HSA-2682334 | 95 | 18 | 8202 | 867 |
MYL9,ARHGEF28,RHOA,EPHA4,GRIN1,YES1,EPHA1,MYL12A,EFNB1,RASA1,EPHA10,LIMK1,EFNA5,MYH14,EPHB4,ARPC2,TIAM1,MYL12B |
| 9.818e-03 | -4.62 | regulation of cellular catabolic process | biological process | GO:0031329 | 599 | 79 | 16441 | 1675 |
DLGAP5,CNOT8,PSME2,TP53,PSME1,BCL2L1,CCNB1,PRKACA,BCAP31,RAD23A,IER3,DAPK2,PSMD1,ZFP36,DAB2IP,TWIST1,CTTN,PLK1,SIRT1,TIMP2,TRIM8,AKT1,PBK,USP18,CDC20,EZR,IDH1,RNF19B,TYSND1,CDK1,IRS2,DNM1L,PLK2,LZTS1,RRAGD,PRKAA2,TNRC6C,PINK1,SCOC,DNAJB2,DAP,PSMD10,TRIB2,RNF128,CTSC,PTEN,CST3,BAX,DAPK1,DRAM1,TRIM21,PLEKHF1,BUB1,PIKFYVE,MYLIP,SOCS5,PSMB4,GCLC,NUB1,FURIN,PIP4K2C,PPARA,PRICKLE1,TP53INP2,PSMA4,PLIN5,GPLD1,PRKAG2,TIMP3,SH3BP4,AURKA,CTSA,CENPE,FZD5,UBE2C,ESPL1,TOB1,USP43,EGLN1 |
| 9.822e-03 | -4.62 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 139 | 23 | 17758 | 1761 |
CLCN3,TRIM8,ZNF84,TEX2,DNAJB14,TP53INP2,BBS2,NCS1,APPBP2,CCDC92,SESN3,GPRC5B,ANKS1B,FRYL,PHLPP2,TMEM30A,DLG1,CCDC82,TMOD2,BTBD3,CCDC88A,NIPA1,DOCK9 |
| 9.829e-03 | -4.62 | Peptidase_C50 | interpro domains | IPR005314 | 2 | 2 | 18293 | 1814 |
CFAP46,ESPL1 |
| 9.829e-03 | -4.62 | Glyco_trans_11 | interpro domains | IPR002516 | 2 | 2 | 18293 | 1814 |
FUT2,FUT1 |
| 9.829e-03 | -4.62 | CO_DH_flav_C | interpro domains | IPR005107 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | PDGF_N | interpro domains | IPR006782 | 2 | 2 | 18293 | 1814 |
PDGFA,PDGFB |
| 9.829e-03 | -4.62 | Glyco_hydro_27/36_CS | interpro domains | IPR000111 | 2 | 2 | 18293 | 1814 |
GLA,NAGA |
| 9.829e-03 | -4.62 | Glyco_hydro_27 | interpro domains | IPR002241 | 2 | 2 | 18293 | 1814 |
GLA,NAGA |
| 9.829e-03 | -4.62 | Sulphate_adenylyltransferase | interpro domains | IPR002650 | 2 | 2 | 18293 | 1814 |
PAPSS2,PAPSS1 |
| 9.829e-03 | -4.62 | Syntaphilin/Syntabulin | interpro domains | IPR028197 | 2 | 2 | 18293 | 1814 |
SYBU,SNPH |
| 9.829e-03 | -4.62 | DUF4757 | interpro domains | IPR031865 | 2 | 2 | 18293 | 1814 |
LMO7,LIMCH1 |
| 9.829e-03 | -4.62 | DUF3350 | interpro domains | IPR021785 | 2 | 2 | 18293 | 1814 |
TBC1D4,TBC1D1 |
| 9.829e-03 | -4.62 | Mopterin_DH_FAD-bd | interpro domains | IPR002346 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | Ald_Oxase/Xan_DH_a/b | interpro domains | IPR000674 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | COQ10_START | interpro domains | IPR005031 | 2 | 2 | 18293 | 1814 |
COQ10A,COQ10B |
| 9.829e-03 | -4.62 | PLC-gamma | interpro domains | IPR016279 | 2 | 2 | 18293 | 1814 |
PLCG1,PLCG2 |
| 9.829e-03 | -4.62 | Cell_morpho_N | interpro domains | IPR025614 | 2 | 2 | 18293 | 1814 |
FRY,FRYL |
| 9.829e-03 | -4.62 | Ald_Oxase/xanthine_DH | interpro domains | IPR016208 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | DUF4927 | interpro domains | IPR032565 | 2 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 9.829e-03 | -4.62 | Isochorismatase-like | interpro domains | IPR000868 | 2 | 2 | 18293 | 1814 |
ISOC2,ISOC1 |
| 9.829e-03 | -4.62 | APS_kinase | interpro domains | IPR002891 | 2 | 2 | 18293 | 1814 |
PAPSS2,PAPSS1 |
| 9.829e-03 | -4.62 | OKL38_fam | interpro domains | IPR029731 | 2 | 2 | 18293 | 1814 |
OSGIN1,OSGIN2 |
| 9.829e-03 | -4.62 | DUF3480 | interpro domains | IPR022557 | 2 | 2 | 18293 | 1814 |
ZFYVE16,ZFYVE9 |
| 9.829e-03 | -4.62 | Cell_Morphogen_C | interpro domains | IPR025481 | 2 | 2 | 18293 | 1814 |
FRY,FRYL |
| 9.829e-03 | -4.62 | ATP-Sase_PUA-like_dom | interpro domains | IPR025980 | 2 | 2 | 18293 | 1814 |
PAPSS2,PAPSS1 |
| 9.829e-03 | -4.62 | AldOxase/xan_DH_Mopterin-bd | interpro domains | IPR008274 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | Sulfurylase_cat_dom | interpro domains | IPR024951 | 2 | 2 | 18293 | 1814 |
PAPSS2,PAPSS1 |
| 9.829e-03 | -4.62 | MOR2-PAG1_mid | interpro domains | IPR029473 | 2 | 2 | 18293 | 1814 |
FRY,FRYL |
| 9.829e-03 | -4.62 | XylT | interpro domains | IPR024448 | 2 | 2 | 18293 | 1814 |
XYLT2,XYLT1 |
| 9.829e-03 | -4.62 | MDFI/MDFIC | interpro domains | IPR026134 | 2 | 2 | 18293 | 1814 |
MDFIC,MDFI |
| 9.829e-03 | -4.62 | DBB_domain | interpro domains | IPR017893 | 2 | 2 | 18293 | 1814 |
BANK1,PIK3AP1 |
| 9.829e-03 | -4.62 | Myrip/Melanophilin | interpro domains | IPR006788 | 2 | 2 | 18293 | 1814 |
MLPH,MYRIP |
| 9.829e-03 | -4.62 | Transform_prot_C-ets | interpro domains | IPR016311 | 2 | 2 | 18293 | 1814 |
ETS2,ETS1 |
| 9.829e-03 | -4.62 | 2Fe-2S-bd | interpro domains | IPR002888 | 2 | 2 | 18293 | 1814 |
AOX1,XDH |
| 9.829e-03 | -4.62 | Nuclear_rcpt_coactivator | interpro domains | IPR017426 | 2 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 9.829e-03 | -4.62 | E3_ub_ligase_SMURF1 | interpro domains | IPR024928 | 2 | 2 | 18293 | 1814 |
WWP1,WWP2 |
| 9.850e-03 | -4.62 | REGULATION_OF_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_SIGNAL_TRANSDUCTION | 219 | 33 | 17758 | 1761 |
SIGIRR,ARAP3,NF2,CDKN1C,RALBP1,RGS20,GRK6,SLC20A1,CARD8,PTEN,TSPAN6,RGS3,IL31RA,SLC44A2,MDFIC,CITED2,F2R,MDFI,MAP3K3,RHOA,RIPK2,LITAF,CD40,MAPK8IP1,PLK2,SECTM1,NOD2,FGD6,RGS14,ARF6,NDFIP1,TRAF5,FGD1 |
| 9.875e-03 | -4.62 | liposaccharide metabolic process | biological process | GO:1903509 | 113 | 20 | 16441 | 1675 |
UGT8,PLAUR,HEXB,ASAH1,NANS,ARSK,CPTP,B4GALNT1,GPLD1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,CTSA,GLA,ARSB,ST3GAL1,NAGA,GM2A |
| 9.891e-03 | -4.62 | V$HSF1_01 | MSigDB lists | V$HSF1_01 | 252 | 37 | 17758 | 1761 |
IER5L,CACNA2D2,ISYNA1,MORF4L2,OSR2,VASH1,TNFRSF19,BCAP31,SIX4,IRF2BPL,RNF220,BCL6,ABCD1,PIM1,PIKFYVE,GAD1,RIMS2,SOCS5,ADAMTS2,TGIF1,BCL9,FOS,LHFPL2,RASGRP2,FOXD2,CACHD1,SCG2,MAP2,DBI,NR4A3,NETO2,FHL1,HSPB1,ACOT7,CMTM4,EHD1,NR2C2 |
| 9.906e-03 | -4.61 | immune response-activating cell surface receptor signaling pathway | biological process | GO:0002429 | 278 | 41 | 16441 | 1675 |
THEMIS2,INPP5D,PSME2,CALM3,BTN3A1,PSMD10,PSME1,TEC,ITPR2,NCKAP1,PRKACA,CACNB4,CALM2,PSMD1,ELMO2,PTEN,PLCG2,BAX,PIK3CA,PIK3CD,PDE4D,SYK,PSMB4,RIPK2,MICB,CALM1,PIK3R1,CR2,PRKCQ,YES1,ITPR3,BCAR1,PSMA4,GPLD1,PLCG1,PTPRJ,LIMK1,ITPR1,NFKBIA,NR4A3,ARPC2 |
| 9.923e-03 | -4.61 | positive regulation of cell division | biological process | GO:0051781 | 128 | 22 | 16441 | 1675 |
PLK1,PDGFC,NKX3-1,RHOA,DLGAP5,MACC1,CIT,RGCC,KIF23,NUSAP1,PDGFB,PDGFA,MDK,PGF,IGF1R,FGFR2,PTEN,KIF14,CDCA5,AURKA,UBE2C,ESPL1 |
| 9.946e-03 | -4.61 | positive regulation of fatty acid oxidation | biological process | GO:0046321 | 14 | 5 | 16441 | 1675 |
IRS2,TWIST1,PLIN5,PPARA,NR4A3 |
| 9.946e-03 | -4.61 | regulation of platelet aggregation | biological process | GO:0090330 | 14 | 5 | 16441 | 1675 |
PRKCQ,SERPINE2,SYK,UBASH3B,PRKG1 |
| 9.946e-03 | -4.61 | cell adhesion mediated by integrin | biological process | GO:0033627 | 14 | 5 | 16441 | 1675 |
NOV,NPNT,ITGA6,COL16A1,L1CAM |
| 9.946e-03 | -4.61 | detection of calcium ion | biological process | GO:0005513 | 14 | 5 | 16441 | 1675 |
CALM3,CALM2,KCNMB4,STIM1,CALM1 |
| 9.946e-03 | -4.61 | nitric oxide biosynthetic process | biological process | GO:0006809 | 14 | 5 | 16441 | 1675 |
SLC7A2,NQO1,AKT1,SPR,CYP1B1 |
| 9.958e-03 | -4.61 | somatodendritic compartment | cellular component | GO:0036477 | 593 | 77 | 17570 | 1756 |
LAMP1,NQO1,EPHA4,RET,FBXO2,LYNX1,HDAC6,DNER,GRM5,NCS1,NOV,IL6ST,CABP1,DPYSL2,SRR,DAB2IP,CTTN,ACSL4,DLG3,SGCE,TIMP2,MBP,PRKAR2B,ITPR3,ALCAM,ARF4,GABARAPL1,PIAS3,TRIM9,MAP2,KCNK1,PLK2,WFS1,SLC9A6,SIPA1L1,NRG1,ITPKA,RGS14,NRGN,COBL,LZTS1,ANXA3,LMTK3,SORT1,ENO2,SERPINE2,CPEB4,LRP4,SLC25A27,SLC1A3,MLPH,IGSF9,ADORA1,SNX18,PTEN,ANKS1B,KCNN4,CST3,MYO5A,DPYSL5,ZWINT,RAPGEF2,GRIN1,ELK1,MAPK8IP1,CDK5R1,STX3,GNAS,PTPRF,CTSV,S100A5,ARRB1,AURKA,GRIN2D,GPER1,SHROOM2,SEMA3A |
| 9.984e-03 | -4.61 | phosphatidylinositol 3-kinase complex, class IA | cellular component | GO:0005943 | 2 | 2 | 17570 | 1756 |
PIK3R1,PIK3CA |
| 9.984e-03 | -4.61 | nuclear aryl hydrocarbon receptor complex | cellular component | GO:0034753 | 2 | 2 | 17570 | 1756 |
AHRR,AHR |
| 9.984e-03 | -4.61 | integrin alphav-beta8 complex | cellular component | GO:0034686 | 2 | 2 | 17570 | 1756 |
ITGAV,ITGB8 |
| 9.984e-03 | -4.61 | glutamate-cysteine ligase complex | cellular component | GO:0017109 | 2 | 2 | 17570 | 1756 |
GCLM,GCLC |
| 9.992e-03 | -4.61 | Trafficking of myristoylated proteins to the cilium | REACTOME pathways | R-HSA-5624138 | 5 | 3 | 8202 | 867 |
RP2,NPHP3,CYS1 |
| 9.992e-03 | -4.61 | APOBEC3G mediated resistance to HIV-1 infection | REACTOME pathways | R-HSA-180689 | 5 | 3 | 8202 | 867 |
HMGA1,PSIP1,APOBEC3G |
| 9.992e-03 | -4.61 | CaMK IV-mediated phosphorylation of CREB | REACTOME pathways | R-HSA-111932 | 5 | 3 | 8202 | 867 |
CALM2,CALM3,CALM1 |
| 9.992e-03 | -4.61 | EF-hand_1 | pfam domains | PF00036 | 14 | 5 | 16629 | 1696 |
CALM3,S100A11,HPCAL4,CABP1,NCS1 |
| 9.992e-03 | -4.61 | PhoLip_ATPase_C | pfam domains | PF16212 | 14 | 5 | 16629 | 1696 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 9.992e-03 | -4.61 | PhoLip_ATPase_N | pfam domains | PF16209 | 14 | 5 | 16629 | 1696 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 9.992e-03 | -4.61 | BEX | pfam domains | PF04538 | 14 | 5 | 16629 | 1696 |
TCEAL8,NGFRAP1,BEX2,WBP5,TCEAL4 |
| 9.996e-03 | -4.61 | Phospholipase C-mediated cascade; FGFR4 | REACTOME pathways | R-HSA-5654228 | 48 | 11 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,FGF19 |
| 9.997e-03 | -4.61 | negative regulation of viral life cycle | biological process | GO:1903901 | 84 | 16 | 16441 | 1675 |
MX1,TRIM8,PLSCR1,TNIP1,APOBEC3D,IFITM3,APOBEC3H,TFAP4,FAM111A,SP100,TRIM21,HDAC1,OAS3,IFIT1,TRIM62,APOBEC3G |
| 1.003e-02 | -4.60 | morphogenesis of a branching structure | biological process | GO:0001763 | 182 | 29 | 16441 | 1675 |
NKX3-1,GRHL2,ST14,SOX9,TFAP2C,CTSZ,PLXNA1,DAG1,EDNRA,SOCS3,CTNNBIP1,NCOA3,FAT4,NPNT,COL13A1,FGFR2,CSF1,BMP7,SPINT2,DLG1,BAX,HOXB13,SOX8,FZD5,ETV4,SEMA3A,SLC12A2,SPRY2,ADAMTS16 |
| 1.004e-02 | -4.60 | DMD (dystrophin) | protein interactions | 1756 | 41 | 10 | 16036 | 1726 |
SNTA1,KCNJ12,SNTB2,TRAF3IP1,UTRN,ARRB1,CADPS2,MAP3K5,SNTB1,DAG1 |
| 1.004e-02 | -4.60 | FAM134C (family with sequence similarity 134, member C) | protein interactions | 162427 | 41 | 10 | 16036 | 1726 |
PLSCR1,TSPAN15,CD63,ATP9A,GNPTAB,XYLT2,POMGNT1,NCAM1,TTYH3,GABARAPL1 |
| 1.004e-02 | -4.60 | - | gene3d domains | 2.30.42.10 | 150 | 26 | 9988 | 1080 |
FRMPD3,LMO7,ARHGEF11,RAPGEF2,MPP1,SNTB2,SCRIB,MPP5,ERBB2IP,SNTB1,PRX,SNTA1,SIPA1L2,PDLIM3,TJP3,SHROOM3,RGS3,LIMK1,SIPA1L1,DLG1,DLG3,MAST4,TIAM1,SHROOM2,DVL2,RIMS2 |
| 1.005e-02 | -4.60 | PDZ | pfam domains | PF00595 | 128 | 22 | 16629 | 1696 |
LMO7,FRMPD3,ARHGEF11,MPP1,SNTB2,RAPGEF2,MPP5,SCRIB,ERBB2IP,SNTB1,SNTA1,PDLIM3,TJP3,SHROOM3,LIMK1,RGS3,DLG1,DLG3,SHROOM2,TIAM1,MAST4,DVL2 |
| 1.005e-02 | -4.60 | Constitutive Signaling by Aberrant PI3K in Cancer | REACTOME pathways | R-HSA-2219530 | 61 | 13 | 8202 | 867 |
PDGFA,IRS2,FGFR2,PIK3R1,PIK3CA,NRG2,ERBB2,NRG1,ERBB3,PIK3CD,PDGFB,FGF19,GAB1 |
| 1.005e-02 | -4.60 | CHANG_CORE_SERUM_RESPONSE_UP | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_UP | 203 | 31 | 17758 | 1761 |
RAB3B,CPEB4,PLAUR,ITGA6,MYBL2,EZR,EIF2AK1,GGH,LOXL2,SLC25A5,SDC1,EMP2,FAM167A,CENPN,GPLD1,PDIA4,STK17A,UAP1,PLOD2,DCK,CORO1C,CEP78,PLK4,UBE2J1,TUBG1,TNFRSF12A,HYLS1,MRPS28,NCEH1,MYBL1,NUP85 |
| 1.005e-02 | -4.60 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 230 | 36 | 8202 | 867 |
PLA2G4A,CD63,DGKQ,HABP4,CALM3,ITPR2,PDGFB,CALM2,PDGFA,GNB5,PLCG2,CD9,PIK3CA,PIK3CD,F2R,DGKG,SYK,RASGRP1,LAMP2,RHOA,AKT1,PIK3R1,CALM1,PRKCQ,ITPR3,BCAR1,GNA11,DGKE,RASGRP2,DGKH,JAK1,SERPINA1,ABHD12,ITPR1,ARRB1,JAK3 |
| 1.006e-02 | -4.60 | V$AREB6_03 | MSigDB lists | V$AREB6_03 | 244 | 36 | 17758 | 1761 |
PPM1J,THRA,ITGA6,RNF182,SLC9A7,PDGFA,CTNNBIP1,EPCAM,ARTN,LLGL2,NPNT,SLC16A6,MEGF8,PAQR5,FUT8,SLC44A1,TOX2,VAT1,CDH3,ERBB3,PLCB2,TRAK2,ZNF462,PVRL4,SSH3,CRB3,STRADB,KIF1C,PPP1R14C,NR4A3,NR4A2,OSR1,PRR15,AHR,RGMA,EHD1 |
| 1.007e-02 | -4.60 | response to unfolded protein | biological process | GO:0006986 | 151 | 25 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,DNAJB2,AMFR,DNAJC3,ERO1A,PDIA5,DNAJB11,FBXO6,DNAJB9,LMNA,CCND1,WIPI1,WFS1,BAX,TMBIM6,DAB2IP,YOD1,MYDGF,MANF,PDIA6,HSPB1,CTDSP2,CTH |
| 1.009e-02 | -4.60 | regulation of response to external stimulus | biological process | GO:0032101 | 854 | 108 | 16441 | 1675 |
SIGIRR,NLRX1,IL15,EPHA4,TP53,LMCD1,IL18,NENF,PLXNA1,SLC7A2,CAMK1D,PDGFB,IER3,CALM2,PDGFA,DAPK2,NOV,AP1M2,ARTN,FAM46A,IL6ST,TSPAN6,BCL6,DUSP10,SEMA3G,IFIT1,CTTN,F2R,APOBEC3G,METAP2,SEMA3B,ENPP4,SIRT1,CD55,TNIP1,ITCH,PBK,PTGER4,SLC35C1,PRKCQ,ATP1B1,F12,CASP4,ABR,SOCS3,GPRC5B,HPSE,DNM1L,CDK19,TRAF3IP1,NOD2,HSPB1,F2RL1,LZTS1,DDX58,PRKAA2,SEMA6B,PINK1,SCOC,SERPINE2,UBASH3B,CALM3,HERC5,SELL,SLC1A3,TEC,ETS1,GSTP1,HLA-A,CD109,ADORA1,GNB5,PTEN,PIK3AP1,MEGF8,FAM13B,PRKG1,ALPK1,PIKFYVE,WNT3A,SYK,KLK5,PSMB4,MPP1,PLAUR,MICB,CALM1,ANO6,GRIN1,PPARA,PIP4K2C,BBS2,STX3,PTPRF,SWAP70,SCG2,SEMA4D,NR1D2,CSF1,MDH1,PPP2R3C,STK39,KLK7,GPER1,FZD5,NDFIP1,SEMA3A,TMEM173 |
| 1.009e-02 | -4.60 | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | MSigDB lists | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | 155 | 25 | 17758 | 1761 |
DLGAP5,PRSS23,CD63,FOXM1,ERBB2,HMGN3,YES1,COX6C,PDGFB,ALCAM,PSIP1,CCND1,CDKN2C,KIF5B,ENPP1,BTG3,TIMP3,CTGF,ITGB8,ARVCF,EPHB4,TOB1,GPX4,FAH,SEPHS1 |
| 1.009e-02 | -4.60 | MULLIGHAN_MLL_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_UP | 362 | 50 | 17758 | 1761 |
GRN,ARHGAP11A,LAMP1,ARHGEF3,RPS6KA1,RASSF7,HEXB,EFHD2,PBX3,TGOLN2,RAB6A,MGST2,HDAC6,ARHGEF40,DENND2D,REPS1,SIRPA,SAC3D1,M6PR,GNS,IQCE,RRBP1,TBCD,CNPY3,SNX10,ALDH3A2,SYK,S100A6,PPIF,S100A4,PTPN9,HTATIP2,C15orf39,SNTB1,RNF19B,RNPEP,NUBP1,ABR,FUCA1,ITGA7,HOXA9,SLC9A6,SFMBT1,PITPNA,EIF4EBP2,CTSA,ARPC2,RGS14,SLC27A3,NXT2 |
| 1.009e-02 | -4.60 | peripheral nervous system development | biological process | GO:0007422 | 70 | 14 | 16441 | 1675 |
UGT8,ARTN,AKT1,TFAP2A,ERBB2,RUNX3,SERPINI1,MPP5,NRG1,ERBB3,SOX8,DAG1,ALDH3A2,ADGRB2 |
| 1.009e-02 | -4.60 | regulation of alpha-beta T cell activation | biological process | GO:0046634 | 70 | 14 | 16441 | 1675 |
CD55,RHOA,RIPK2,ITCH,HLA-E,BCL6,PRKCQ,IL18,C10orf54,JAK3,SYK,HLA-A,SOCS5,CD83 |
| 1.010e-02 | -4.60 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | MSigDB lists | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 79 | 15 | 17758 | 1761 |
CASP3,RASGRF1,ARHGEF3,RHOA,RIPK2,ARHGEF11,NGFRAP1,NFKBIA,HDAC1,TIAM1,ARHGEF9,ABR,ARHGEF16,ARHGEF4,FGD1 |
| 1.010e-02 | -4.60 | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | 79 | 15 | 17758 | 1761 |
MYO5B,HSF2,MITF,ERBB2,RAB6A,EPHA1,CRABP2,PTGFRN,FBLN1,CYP39A1,APPBP2,NRP2,CKS2,PCSK5,SEMA3B |
| 1.011e-02 | -4.59 | Crosslinking of collagen fibrils | REACTOME pathways | R-HSA-2243919 | 9 | 4 | 8202 | 867 |
LOXL2,PCOLCE,BMP1,TLL2 |
| 1.011e-02 | -4.59 | Elevation of cytosolic Ca2+ levels | REACTOME pathways | R-HSA-139853 | 9 | 4 | 8202 | 867 |
ITPR2,ITPR3,STIM1,ITPR1 |
| 1.012e-02 | -4.59 | GSE20715_0H_VS_6H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_DN | 195 | 30 | 17758 | 1761 |
DPYSL5,NUDT6,HSPG2,GCLC,FRMD6,DRAP1,INPP5D,ITGA6,FURIN,OSGIN2,ITPR3,LEPR,EFNB1,POR,STX3,ELF3,SOCS3,A4GALT,PELI2,NKD1,CLIP4,RAB20,CRY2,CDK18,LIMCH1,PLD1,NPTXR,COL16A1,OSGIN1,WBP5 |
| 1.012e-02 | -4.59 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | 195 | 30 | 17758 | 1761 |
ERLEC1,FRMD4A,NLRX1,TACC1,POC1B,SOX9,HABP4,PARP4,PRICKLE1,C15orf39,STK17B,FZD7,CMTM7,CCDC92,SLC6A6,TMEM87B,RNF128,RBM47,AIM1,FAM63A,ABCD1,MDH1,RP2,KLF9,TMEM120A,CNOT6L,DLG3,MGAT5,MYO5A,MAPK12 |
| 1.014e-02 | -4.59 | ZHU_CMV_8_HR_DN | MSigDB lists | ZHU_CMV_8_HR_DN | 51 | 11 | 17758 | 1761 |
TFAP4,WEE1,IGF1R,NR3C1,IL6ST,TFAP2A,ACO1,IGFBP2,FBLN1,AHR,LMNA |
| 1.014e-02 | -4.59 | parietal_lobe | COSMIC cancer mutations | parietal_lobe | 58 | 12 | 17775 | 1757 |
GNAS,CDKN2C,NF2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,RTKN2,IDH1,GNA11 |
| 1.014e-02 | -4.59 | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 58 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.016e-02 | -4.59 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | 163 | 26 | 17758 | 1761 |
TGIF1,LZTFL1,COQ10B,TSC22D3,ITCH,ITGA6,EPHA4,HABP4,LDB2,FOS,CDK5R1,RASGRP2,IRS2,C16orf74,RALGPS2,LYPD3,PELI2,AIM1,KLF3,SGK1,NR4A2,CITED2,MYLIP,TOB1,MAFF,PCSK5 |
| 1.017e-02 | -4.59 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_UP | 187 | 29 | 17758 | 1761 |
EPB41L5,SUN2,PGM1,RIPK2,HEBP1,RALBP1,TSC22D3,PLEKHO1,SAT1,PTTG1,ARL4C,UTRN,C6orf106,CD274,BCAR3,CCDC92,TAPBP,WEE1,GPRC5B,TMEM51,ZNF704,SFMBT1,GRIN2D,IRF7,RFX5,ATP1B3,RGS14,RARG,RRAGD |
| 1.017e-02 | -4.59 | GSE7852_TREG_VS_TCONV_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_DN | 187 | 29 | 17758 | 1761 |
ORAI2,DAP,PLEKHO1,ARL4C,GABRG2,PRKCQ,NPC2,GRK6,DSE,KCTD2,FAM101B,SLC20A1,LBR,OTUD1,SETDB2,CDH1,FAAH,RINL,KBTBD2,ITPR1,PPM1H,SGK1,FAM102A,HS3ST3B1,WBSCR27,ALS2CL,CTDSP2,RNF146,PAQR7 |
| 1.017e-02 | -4.59 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | 187 | 29 | 17758 | 1761 |
SUN2,FBLIM1,TRIM8,LONRF3,EPAS1,GNPDA1,CAMKK1,MPP1,RASA2,EIF5A2,HABP4,PRICKLE1,SLC36A4,SYTL4,DNAJB14,PRKRA,SEPP1,DHRS3,PDIK1L,NCOA3,MID1IP1,HPSE,COL13A1,FUT1,SERPINB6,FHL1,TOB1,SULF2,SOCS5 |
| 1.017e-02 | -4.59 | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | 187 | 29 | 17758 | 1761 |
ATL1,MTM1,SPRED1,SGCE,SORT1,ARAP3,SERPINE2,HEBP1,MRS2,GPSM2,CCNF,HDAC6,OAT,GLT8D2,LMNA,HMGXB4,RBL1,METTL7A,GALNS,AMMECR1,DBI,CEP78,ECI2,FHL1,SOX8,CCNB2,SYK,CKAP4,METAP2 |
| 1.017e-02 | -4.59 | insulin-like growth factor binding | molecular function | GO:0005520 | 25 | 7 | 16491 | 1673 |
IGFBP2,NOV,ITGAV,IGF1R,CTGF,IGFBP6,CYR61 |
| 1.018e-02 | -4.59 | PARENT_MTOR_SIGNALING_UP | MSigDB lists | PARENT_MTOR_SIGNALING_UP | 545 | 71 | 17758 | 1761 |
LTBP1,CPT2,TSC22D3,CAST,IQGAP1,DNAJC3,HDAC6,ABCD4,ST5,TRANK1,CYP4F11,IQCE,PAPSS1,KLF3,VAT1,CTH,MAP3K3,SMARCA2,ING1,SYNE2,CASP9,SLC11A2,CD40,ASB13,KCTD2,MAP3K6,RHEB,GABARAPL1,PLCG1,SLC25A4,KLF12,KCNK1,MADD,TRIOBP,AGFG2,EPB41L4A,SLC27A3,F2RL1,BIN1,CD63,PEX6,ATP9A,ARL4C,CYB561,SAMD9,PSIP1,TMBIM6,ECI2,ALDH7A1,CITED2,TPCN1,ALDH3A2,TBC1D8B,OXR1,PPARA,SCRIB,PDK3,SNTB1,RANBP9,GNAS,PRKAG2,SLC4A4,ITGA7,ARRB1,OTUB2,CDK18,CABIN1,MAP3K5,SLC25A38,SEMA3A,DOCK9 |
| 1.019e-02 | -4.59 | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | 171 | 27 | 17758 | 1761 |
CTHRC1,CCDC109B,TTC39B,PRSS23,IL15,SDC4,RGS20,PDIA3,FNDC3A,PRRG4,CRISPLD2,NRP2,PLS3,GNS,BTG3,GNPTAB,RAP2C,RAB11FIP1,TMOD2,PLD1,SNX10,CPEB2,COBL,RARG,ESYT2,LAMP3,ABCG1 |
| 1.020e-02 | -4.59 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | 179 | 28 | 17758 | 1761 |
SLC25A24,CDH22,LRP4,PTTG1,SYBU,GRIN1,ERI2,TESK2,GGH,LGALS3BP,SH2D4A,CCDC92,GALNT3,AMZ2,TFAP4,RCN1,BTG3,PVRL2,RUNDC3B,PRDM5,MAP3K9,KCNS3,RAB11FIP1,SCARA3,MAST4,TRAF5,PKIA,FARP2 |
| 1.020e-02 | -4.59 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 179 | 28 | 17758 | 1761 |
ARMCX3,NFKBIE,ATP9A,ITCH,RASSF7,HMG20B,CCDC68,SLC36A4,TGFBR1,LRRC1,SAV1,TXNDC11,HMGXB4,DNAJB9,M6PR,SETDB2,FAM46A,UAP1,ITPR1,VAT1,PIK3C2B,PDE4D,TANC2,MAFF,ABCA1,DVL2,SNPH,SULF2 |
| 1.022e-02 | -4.58 | single organism cell adhesion | biological process | GO:0098602 | 471 | 64 | 16441 | 1675 |
MYL9,IL15,RET,TP53,PKP2,NOV,CDH1,NPNT,KIF14,DLG1,CDH3,PIK3CD,CYP1B1,CAMSAP3,RIPK2,TNIP1,FZD4,PTPRU,PTGER4,EZR,MYL12A,FZD7,DDOST,AXL,ANXA9,F2RL1,HSPB1,FBLIM1,RUNX2,BVES,HLA-E,SOX9,BTN3A1,MERTK,SRPX2,IL18R1,CYR61,KIF13B,BMP7,BAX,ARVCF,WNT3A,SYK,GCNT1,RHOA,PODXL2,MICB,RC3H2,VEZT,SCRIB,EPHA1,FNDC3A,ANTXR1,CDK5R1,FAS,GNAS,COL13A1,SEMA4D,ITGA7,PLPP3,ITGAV,FZD5,ICOSLG,L1CAM |
| 1.022e-02 | -4.58 | mediastinum | COSMIC cancer mutations | mediastinum | 38 | 9 | 17775 | 1757 |
CDKN2C,AKT1,FGFR2,RET,PIK3R1,PIK3CA,ERBB2,IDH1,JAK3 |
| 1.026e-02 | -4.58 | developmental growth | biological process | GO:0048589 | 328 | 47 | 16441 | 1675 |
EMX1,GRHL2,ADD1,CDKN1C,IQGAP1,LRP4,SOX9,TP53,TEC,CCNB1,STIL,NRP2,NOV,PTEN,FLRT3,ADAM15,PDE4D,WNT3A,SLC12A2,SPRY2,EPB41L5,FMN1,SALL4,ASPM,BCL9,RC3H2,TFAP2C,KLK6,PRKCQ,ICMT,ALCAM,C3orf58,FZD7,GNAS,NCOA3,TIMP3,FGFR2,PTK7,SLC9A6,CSF1,AURKA,EFNA5,ZMIZ1,NCAPG2,SEMA3A,RARG,COBL |
| 1.026e-02 | -4.58 | protein kinase C binding | molecular function | GO:0005080 | 50 | 11 | 16491 | 1673 |
TOP2A,ADD3,AKT1,DACT1,SDC4,PRKCDBP,PKP2,ITGAV,PKN1,HSPB1,HDAC9 |
| 1.029e-02 | -4.58 | xanthine dehydrogenase activity | molecular function | GO:0004854 | 2 | 2 | 16491 | 1673 |
XDH,AOX1 |
| 1.029e-02 | -4.58 | alpha-galactosidase activity | molecular function | GO:0004557 | 2 | 2 | 16491 | 1673 |
GLA,NAGA |
| 1.029e-02 | -4.58 | leukemia inhibitory factor receptor activity | molecular function | GO:0004923 | 2 | 2 | 16491 | 1673 |
LIFR,IL6ST |
| 1.029e-02 | -4.58 | galactoside 2-alpha-L-fucosyltransferase activity | molecular function | GO:0008107 | 2 | 2 | 16491 | 1673 |
FUT2,FUT1 |
| 1.029e-02 | -4.58 | glutamate-cysteine ligase activity | molecular function | GO:0004357 | 2 | 2 | 16491 | 1673 |
GCLM,GCLC |
| 1.029e-02 | -4.58 | interleukin-27 receptor activity | molecular function | GO:0045509 | 2 | 2 | 16491 | 1673 |
IL27RA,IL6ST |
| 1.029e-02 | -4.58 | sulfate adenylyltransferase activity | molecular function | GO:0004779 | 2 | 2 | 16491 | 1673 |
PAPSS2,PAPSS1 |
| 1.029e-02 | -4.58 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | molecular function | GO:0016726 | 2 | 2 | 16491 | 1673 |
XDH,AOX1 |
| 1.029e-02 | -4.58 | sulfate adenylyltransferase (ATP) activity | molecular function | GO:0004781 | 2 | 2 | 16491 | 1673 |
PAPSS2,PAPSS1 |
| 1.029e-02 | -4.58 | alpha-(1,2)-fucosyltransferase activity | molecular function | GO:0031127 | 2 | 2 | 16491 | 1673 |
FUT2,FUT1 |
| 1.029e-02 | -4.58 | biliverdin reductase activity | molecular function | GO:0004074 | 2 | 2 | 16491 | 1673 |
BLVRA,BLVRB |
| 1.029e-02 | -4.58 | N-acylneuraminate cytidylyltransferase activity | molecular function | GO:0008781 | 2 | 2 | 16491 | 1673 |
CMAS,NANS |
| 1.029e-02 | -4.58 | adenine transmembrane transporter activity | molecular function | GO:0015207 | 2 | 2 | 16491 | 1673 |
SLC25A4,SLC25A5 |
| 1.029e-02 | -4.58 | N-acetylgalactosamine-4-sulfatase activity | molecular function | GO:0003943 | 2 | 2 | 16491 | 1673 |
ARSB,GALNS |
| 1.029e-02 | -4.58 | adenylylsulfate kinase activity | molecular function | GO:0004020 | 2 | 2 | 16491 | 1673 |
PAPSS2,PAPSS1 |
| 1.031e-02 | -4.57 | protein secretion | biological process | GO:0009306 | 136 | 23 | 16441 | 1675 |
RAB3B,BTN3A1,BTN3A2,RNF19B,ERP29,OPTN,PDIA4,GNAS,SVBP,RAB15,RAB11FIP2,SCG2,GNPTAB,NOD2,LTBP2,ARL4D,RAB27B,F2RL1,S100A13,ABCA1,RIMS2,MYO5A,PCSK5 |
| 1.031e-02 | -4.57 | glial cell differentiation | biological process | GO:0010001 | 136 | 23 | 16441 | 1675 |
EMX1,WASF3,HES1,RHOA,AKT1,HDAC11,SOX9,ERBB2,MPP5,DNER,NFIB,DAG1,NFIX,CDKN2C,PTPRJ,PTEN,PLPP3,CD9,TFAP2A,DUSP10,NRG1,ERBB3,SOX8 |
| 1.032e-02 | -4.57 | MODULE_120 | MSigDB lists | MODULE_120 | 72 | 14 | 17758 | 1761 |
SNTA1,LTBP1,IGF1R,IL15RA,TRIP10,COG2,PLOD2,CR2,COL18A1,SLC11A2,NKRF,SERPINI1,PHLDA1,ARHGAP35 |
| 1.032e-02 | -4.57 | COATES_MACROPHAGE_M1_VS_M2_DN | MSigDB lists | COATES_MACROPHAGE_M1_VS_M2_DN | 72 | 14 | 17758 | 1761 |
FBLIM1,LASP1,HS6ST1,PINK1,GPRC5B,FAM199X,EFHD2,GDF15,FAM198B,MGST2,EGLN3,ARSK,XDH,ATG4D |
| 1.032e-02 | -4.57 | DITTMER_PTHLH_TARGETS_DN | MSigDB lists | DITTMER_PTHLH_TARGETS_DN | 72 | 14 | 17758 | 1761 |
PSMB4,TBC1D1,RAPGEF2,ITGA6,PIK3R1,AOX1,PIK3CA,ZDHHC7,ALDH7A1,ARPC2,SPTLC2,SEMA3A,LMNA,FAH |
| 1.032e-02 | -4.57 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 72 | 14 | 17758 | 1761 |
COL9A3,ACACB,ALDH5A1,CAPN6,FGFR2,RET,TLE1,COL4A5,IGFBP2,ISYNA1,EPB41L4B,KBTBD11,NFIB,MDFI |
| 1.032e-02 | -4.57 | positive regulation of sodium ion transport | biological process | GO:0010765 | 37 | 9 | 16441 | 1675 |
PRSS8,SCN5A,AKT1,SGK3,SGK1,PKP2,ATP1B3,ATP1B1,CHP1 |
| 1.032e-02 | -4.57 | porphyrin-containing compound metabolic process | biological process | GO:0006778 | 37 | 9 | 16441 | 1675 |
FECH,CYP1A1,BLVRB,NFE2L1,SLC11A2,EIF2AK1,BLVRA,SLC25A38,SPTB |
| 1.032e-02 | -4.57 | cytoskeleton-dependent cytokinesis | biological process | GO:0061640 | 37 | 9 | 16441 | 1675 |
PLK1,RHOA,KIF20A,SNX18,CKAP2,KIF23,NUSAP1,ANLN,RASA1 |
| 1.035e-02 | -4.57 | PDZ | smart domains | SM00228 | 149 | 26 | 9131 | 997 |
LMO7,FRMPD3,ARHGEF11,MPP1,SNTB2,RAPGEF2,MPP5,SCRIB,ERBB2IP,SNTB1,PRX,SNTA1,SIPA1L2,PDLIM3,TJP3,SHROOM3,LIMK1,RGS3,SIPA1L1,DLG1,DLG3,SHROOM2,TIAM1,MAST4,DVL2,RIMS2 |
| 1.037e-02 | -4.57 | Mitotic G2-G2/M phases | REACTOME pathways | R-HSA-453274 | 117 | 21 | 8202 | 867 |
PLK1,CEP70,FOXM1,MYBL2,PRKAR2B,PKMYT1,CCNB1,BORA,PRKACA,CDK1,OPTN,WEE1,CNTRL,CEP78,PLK4,NEK2,AURKA,TUBG1,NDE1,CEP41,CCNB2 |
| 1.037e-02 | -4.57 | protein-pyridoxal-5-phosphate linkage | biological process | GO:0018352 | 2 | 2 | 16441 | 1675 |
GAD1,CTH |
| 1.037e-02 | -4.57 | cellular response to redox state | biological process | GO:0071461 | 2 | 2 | 16441 | 1675 |
ARHGDIB,VASN |
| 1.037e-02 | -4.57 | negative regulation of neurotrophin production | biological process | GO:0032900 | 2 | 2 | 16441 | 1675 |
ADORA1,FURIN |
| 1.037e-02 | -4.57 | interleukin-27-mediated signaling pathway | biological process | GO:0070106 | 2 | 2 | 16441 | 1675 |
IL27RA,IL6ST |
| 1.037e-02 | -4.57 | vesicle targeting, trans-Golgi to endosome | biological process | GO:0048203 | 2 | 2 | 16441 | 1675 |
AP1AR,WIPI1 |
| 1.037e-02 | -4.57 | nuclear migration along microfilament | biological process | GO:0031022 | 2 | 2 | 16441 | 1675 |
SUN2,SYNE2 |
| 1.037e-02 | -4.57 | nucleotide-binding oligomerization domain containing 1 signaling pathway | biological process | GO:0070427 | 2 | 2 | 16441 | 1675 |
RIPK2,NFKBIA |
| 1.037e-02 | -4.57 | basal protein localization | biological process | GO:0045175 | 2 | 2 | 16441 | 1675 |
ERBB2IP,NCKAP1 |
| 1.037e-02 | -4.57 | negative regulation of vascular smooth muscle contraction | biological process | GO:1904694 | 2 | 2 | 16441 | 1675 |
DOCK4,DOCK5 |
| 1.037e-02 | -4.57 | regulation of eIF2 alpha phosphorylation by heme | biological process | GO:0010999 | 2 | 2 | 16441 | 1675 |
FECH,EIF2AK1 |
| 1.037e-02 | -4.57 | positive regulation of DNA endoreduplication | biological process | GO:0032877 | 2 | 2 | 16441 | 1675 |
E2F7,E2F8 |
| 1.037e-02 | -4.57 | regulation of cell motility involved in somitogenic axis elongation | biological process | GO:0090249 | 2 | 2 | 16441 | 1675 |
PPP2R3A,NKD1 |
| 1.037e-02 | -4.57 | negative regulation of oxidative phosphorylation uncoupler activity | biological process | GO:2000276 | 2 | 2 | 16441 | 1675 |
PPIF,TWIST1 |
| 1.037e-02 | -4.57 | negative regulation of phosphatidylinositol biosynthetic process | biological process | GO:0010512 | 2 | 2 | 16441 | 1675 |
PDGFA,PDGFB |
| 1.037e-02 | -4.57 | regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | biological process | GO:0072363 | 2 | 2 | 16441 | 1675 |
PPARA,TP53 |
| 1.037e-02 | -4.57 | female courtship behavior | biological process | GO:0008050 | 2 | 2 | 16441 | 1675 |
THRB,THRA |
| 1.037e-02 | -4.57 | activation of APC-Cdc20 complex activity | biological process | GO:0007092 | 2 | 2 | 16441 | 1675 |
PLK1,PTEN |
| 1.037e-02 | -4.57 | negative regulation of integrin activation | biological process | GO:0033624 | 2 | 2 | 16441 | 1675 |
KIF14,PTGER4 |
| 1.037e-02 | -4.57 | positive regulation of ubiquitin protein ligase activity | biological process | GO:1904668 | 2 | 2 | 16441 | 1675 |
PLK1,PTEN |
| 1.037e-02 | -4.57 | ectodermal cell fate commitment | biological process | GO:0001712 | 2 | 2 | 16441 | 1675 |
ETS2,ELF5 |
| 1.037e-02 | -4.57 | negative regulation of cardioblast differentiation | biological process | GO:0051892 | 2 | 2 | 16441 | 1675 |
PRICKLE1,WNT3A |
| 1.039e-02 | -4.57 | PID_FAK_PATHWAY | MSigDB lists | PID_FAK_PATHWAY | 58 | 12 | 17758 | 1761 |
CCND1,PLCG1,RHOA,ARHGEF11,PIK3R1,PIK3CA,ITGAV,YES1,BCAR1,ETS1,RASA1,ARHGAP35 |
| 1.040e-02 | -4.57 | negative regulation of binding | biological process | GO:0051100 | 121 | 21 | 16441 | 1675 |
ZNF462,EPB41L5,NKX3-1,HABP4,PPARA,AES,PDGFB,NFIB,CTNNBIP1,TFAP4,PTPRF,SP100,NFKBIA,BAX,NEK2,AURKA,SORL1,TMBIM6,ADAM15,IFIT1,MDFI |
| 1.040e-02 | -4.57 | Ald_Xan_dh_C | pfam domains | PF01315 | 2 | 2 | 16629 | 1696 |
XDH,AOX1 |
| 1.040e-02 | -4.57 | Glyco_transf_11 | pfam domains | PF01531 | 2 | 2 | 16629 | 1696 |
FUT2,FUT1 |
| 1.040e-02 | -4.57 | Fer2_2 | pfam domains | PF01799 | 2 | 2 | 16629 | 1696 |
XDH,AOX1 |
| 1.040e-02 | -4.57 | MDFI | pfam domains | PF15316 | 2 | 2 | 16629 | 1696 |
MDFIC,MDFI |
| 1.040e-02 | -4.57 | APS_kinase | pfam domains | PF01583 | 2 | 2 | 16629 | 1696 |
PAPSS2,PAPSS1 |
| 1.040e-02 | -4.57 | DBB | pfam domains | PF14545 | 2 | 2 | 16629 | 1696 |
BANK1,PIK3AP1 |
| 1.040e-02 | -4.57 | Xylo_C | pfam domains | PF12529 | 2 | 2 | 16629 | 1696 |
XYLT2,XYLT1 |
| 1.040e-02 | -4.57 | Syntaphilin | pfam domains | PF15290 | 2 | 2 | 16629 | 1696 |
SYBU,SNPH |
| 1.040e-02 | -4.57 | Peptidase_C50 | pfam domains | PF03568 | 2 | 2 | 16629 | 1696 |
CFAP46,ESPL1 |
| 1.040e-02 | -4.57 | DUF4927 | pfam domains | PF16279 | 2 | 2 | 16629 | 1696 |
NCOA3,NCOA2 |
| 1.040e-02 | -4.57 | FAD_binding_5 | pfam domains | PF00941 | 2 | 2 | 16629 | 1696 |
XDH,AOX1 |
| 1.040e-02 | -4.57 | Polyketide_cyc | pfam domains | PF03364 | 2 | 2 | 16629 | 1696 |
COQ10A,COQ10B |
| 1.040e-02 | -4.57 | Rab_eff_C | pfam domains | PF04698 | 2 | 2 | 16629 | 1696 |
MLPH,MYRIP |
| 1.040e-02 | -4.57 | Isochorismatase | pfam domains | PF00857 | 2 | 2 | 16629 | 1696 |
ISOC2,ISOC1 |
| 1.040e-02 | -4.57 | MOR2-PAG1_C | pfam domains | PF14225 | 2 | 2 | 16629 | 1696 |
FRY,FRYL |
| 1.040e-02 | -4.57 | PUA_2 | pfam domains | PF14306 | 2 | 2 | 16629 | 1696 |
PAPSS2,PAPSS1 |
| 1.040e-02 | -4.57 | DUF3350 | pfam domains | PF11830 | 2 | 2 | 16629 | 1696 |
TBC1D4,TBC1D1 |
| 1.040e-02 | -4.57 | DUF4757 | pfam domains | PF15949 | 2 | 2 | 16629 | 1696 |
LMO7,LIMCH1 |
| 1.040e-02 | -4.57 | Melibiase_2 | pfam domains | PF16499 | 2 | 2 | 16629 | 1696 |
GLA,NAGA |
| 1.040e-02 | -4.57 | CO_deh_flav_C | pfam domains | PF03450 | 2 | 2 | 16629 | 1696 |
XDH,AOX1 |
| 1.040e-02 | -4.57 | MOR2-PAG1_N | pfam domains | PF14222 | 2 | 2 | 16629 | 1696 |
FRY,FRYL |
| 1.040e-02 | -4.57 | ATP-sulfurylase | pfam domains | PF01747 | 2 | 2 | 16629 | 1696 |
PAPSS2,PAPSS1 |
| 1.040e-02 | -4.57 | Ald_Xan_dh_C2 | pfam domains | PF02738 | 2 | 2 | 16629 | 1696 |
XDH,AOX1 |
| 1.040e-02 | -4.57 | DUF3480 | pfam domains | PF11979 | 2 | 2 | 16629 | 1696 |
ZFYVE16,ZFYVE9 |
| 1.040e-02 | -4.57 | PDGF_N | pfam domains | PF04692 | 2 | 2 | 16629 | 1696 |
PDGFA,PDGFB |
| 1.040e-02 | -4.57 | MOR2-PAG1_mid | pfam domains | PF14228 | 2 | 2 | 16629 | 1696 |
FRY,FRYL |
| 1.040e-02 | -4.57 | AR (androgen receptor) | protein interactions | 367 | 272 | 42 | 16036 | 1726 |
CASP3,RUNX2,REPS2,CUL4B,ETV5,TP53,AES,TRIM68,APPBP2,ELF3,CCND1,PTEN,IL6ST,GTF2F2,PRKG1,NR2C1,CTDSP2,NCOA2,SIRT1,DDB2,TGIF1,SMARCA2,AKT1,NR3C1,CALM1,CDK1,RANBP9,KDM4D,PIAS3,NCOA3,IDE,SLC25A4,WIPI1,RBL1,HDAC1,NDE1,ZMIZ1,NR3C2,HIPK3,APOL2,AHR,NR2C2 |
| 1.040e-02 | -4.57 | reactive oxygen species biosynthetic process | biological process | GO:1903409 | 25 | 7 | 16441 | 1675 |
DUOX1,CYP1A1,SLC7A2,NQO1,AKT1,SPR,CYP1B1 |
| 1.040e-02 | -4.57 | response to corticosterone | biological process | GO:0051412 | 25 | 7 | 16441 | 1675 |
CALM3,CALM2,CCND1,FOS,CALM1,FOSB,BAX |
| 1.040e-02 | -4.57 | regulation of cellular senescence | biological process | GO:2000772 | 25 | 7 | 16441 | 1675 |
SIRT1,TWIST1,HMGA1,VASH1,NUAK1,BCL6,TP53 |
| 1.040e-02 | -4.57 | regulation of microtubule depolymerization | biological process | GO:0031114 | 25 | 7 | 16441 | 1675 |
AURKA,GAS2L1,MID1IP1,CCNB1,HDAC6,CKAP2,APC2 |
| 1.041e-02 | -4.57 | Sphingolipid signaling pathway | KEGG pathways | ko04071 | 120 | 22 | 6908 | 758 |
RHOA,AKT1,PIK3R1,TP53,ASAH1,SPTLC2,PPP2R3A,SGPL1,ADORA1,PPP2R5A,PTEN,BAX,PIK3CA,PPP2R3C,MAPK11,PLD1,PIK3CD,MAP3K5,PLCB2,PPP2R2D,MAPK12,ABCC1 |
| 1.041e-02 | -4.57 | Sphingolipid signaling pathway | KEGG pathways | hsa04071 | 120 | 22 | 6908 | 758 |
RHOA,AKT1,PIK3R1,TP53,ASAH1,SPTLC2,PPP2R3A,SGPL1,ADORA1,PPP2R5A,PTEN,BAX,PIK3CA,PPP2R3C,MAPK11,PLD1,PIK3CD,MAP3K5,PLCB2,PPP2R2D,MAPK12,ABCC1 |
| 1.042e-02 | -4.56 | human chr5q21 | chromosome location | human chr5q21 | 7 | 3 | 26250 | 1887 |
EFNA5,CPEB4,GNPDA1 |
| 1.043e-02 | -4.56 | REACTOME_NETRIN1_SIGNALING | MSigDB lists | REACTOME_NETRIN1_SIGNALING | 38 | 9 | 17758 | 1761 |
PLCG1,RGMB,EZR,PITPNA,NTN4,PRKCQ,UNC5B,RGMA,NEO1 |
| 1.043e-02 | -4.56 | PID_ERBB4_PATHWAY | MSigDB lists | PID_ERBB4_PATHWAY | 38 | 9 | 17758 | 1761 |
ITCH,LRIG1,PIK3R1,PIK3CA,NRG2,ERBB2,NRG1,WWP1,PIK3CD |
| 1.043e-02 | -4.56 | RHO_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | RHO_PROTEIN_SIGNAL_TRANSDUCTION | 38 | 9 | 17758 | 1761 |
ARAP3,RHOA,LIMK1,RALBP1,FGD6,ARHGDIB,ARF6,ABCA1,FGD1 |
| 1.043e-02 | -4.56 | chr3q22 | MSigDB lists | chr3q22 | 38 | 9 | 17758 | 1761 |
CEP70,RASA2,RYK,TRPC1,MRAS,ATP1B3,NPHP3,PPP2R3A,DZIP1L |
| 1.043e-02 | -4.56 | PID_FAS_PATHWAY | MSigDB lists | PID_FAS_PATHWAY | 38 | 9 | 17758 | 1761 |
CASP3,AKT1,PIK3R1,PIK3CA,EZR,MAPK11,PIK3CD,SYK,FAS |
| 1.043e-02 | -4.56 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | 38 | 9 | 17758 | 1761 |
BIN1,NFKBIE,MMD,LPGAT1,ITPR1,AIM1,SERPINB1,AHR,CD83 |
| 1.043e-02 | -4.56 | NAKAMURA_ADIPOGENESIS_EARLY_DN | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_DN | 38 | 9 | 17758 | 1761 |
COL9A3,TIMP3,ITGA3,SERPINE2,PRSS23,CYR61,CALD1,GDF15,ITGAV |
| 1.043e-02 | -4.56 | PID_BCR_5PATHWAY | MSigDB lists | PID_BCR_5PATHWAY | 65 | 13 | 17758 | 1761 |
AKT1,PTEN,PIK3AP1,INPP5D,PLCG2,NFKBIA,PIK3R1,PIK3CA,ELK1,FOS,ETS1,SYK,RASA1 |
| 1.048e-02 | -4.56 | EPHB-mediated forward signaling | REACTOME pathways | R-HSA-3928662 | 42 | 10 | 8202 | 867 |
ARHGEF28,RHOA,LIMK1,GRIN1,EPHB4,YES1,ARPC2,TIAM1,EFNB1,RASA1 |
| 1.048e-02 | -4.56 | Non-integrin membrane-ECM interactions | REACTOME pathways | R-HSA-3000171 | 42 | 10 | 8202 | 867 |
PDGFA,HSPG2,ITGA6,SDC4,NTN4,ITGAV,SDC1,DDR1,PDGFB,DAG1 |
| 1.048e-02 | -4.56 | Netrin-1 signaling | REACTOME pathways | R-HSA-373752 | 42 | 10 | 8202 | 867 |
PLCG1,RGMB,TRPC1,EZR,PITPNA,NTN4,PRKCQ,UNC5B,RGMA,NEO1 |
| 1.048e-02 | -4.56 | Elastic fibre formation | REACTOME pathways | R-HSA-1566948 | 42 | 10 | 8202 | 867 |
LTBP1,FBLN5,ITGB8,BMP7,FURIN,LTBP2,ITGAV,LOXL2,FBLN1,LTBP3 |
| 1.051e-02 | -4.56 | STK33_SKM_DN | MSigDB lists | STK33_SKM_DN | 253 | 37 | 17758 | 1761 |
FBLIM1,CAST,GALNT12,PYROXD2,DDIT4L,CA8,FAM46C,BEX2,BMP2K,FOXP2,CXCL16,SPIN4,CALD1,AIM1,TMEM143,ZDHHC23,SORL1,TSPAN13,ACOX2,RAB27B,OGDHL,CDA,CXorf57,TMEM144,PRKAR2B,RAB38,SNTB1,CYP4F3,SPNS3,ARHGEF26,PRDM11,PLCH1,BANK1,PPM1H,SH3BGRL2,TANC2,TMEM173 |
| 1.053e-02 | -4.55 | LRRC29 (leucine rich repeat containing 29) | protein interactions | 26231 | 5 | 3 | 16036 | 1726 |
HOOK1,STIL,ADAMTSL4 |
| 1.053e-02 | -4.55 | KLHL35 (kelch-like family member 35) | protein interactions | 283212 | 5 | 3 | 16036 | 1726 |
MX1,TGFBR1,APPBP2 |
| 1.053e-02 | -4.55 | SEMA3B (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B) | protein interactions | 7869 | 5 | 3 | 16036 | 1726 |
SEMA3A,NRP2,SEMA3B |
| 1.053e-02 | -4.55 | TUBB (tubulin, beta class I) | protein interactions | 615087 | 5 | 3 | 16036 | 1726 |
DPYSL5,DPYSL2,DPYSL3 |
| 1.053e-02 | -4.55 | Ubc (ubiquitin C) | protein interactions | 22190 | 5 | 3 | 16036 | 1726 |
DDX58,CDKN1B,SYK |
| 1.053e-02 | -4.55 | TMEM230 (transmembrane protein 230) | protein interactions | 29058 | 5 | 3 | 16036 | 1726 |
ARL4D,TMEM9,LMNA |
| 1.053e-02 | -4.55 | GPLD1 (glycosylphosphatidylinositol specific phospholipase D1) | protein interactions | 2822 | 5 | 3 | 16036 | 1726 |
CD55,ALPP,GM2A |
| 1.053e-02 | -4.55 | CTRL (chymotrypsin-like) | protein interactions | 1506 | 5 | 3 | 16036 | 1726 |
PSME1,PSME2,PDIA5 |
| 1.053e-02 | -4.55 | KLK13 (kallikrein related peptidase 13) | protein interactions | 26085 | 5 | 3 | 16036 | 1726 |
SERPINB6,SERPINA1,SERPINE2 |
| 1.053e-02 | -4.55 | ROR1 (receptor tyrosine kinase-like orphan receptor 1) | protein interactions | 4919 | 5 | 3 | 16036 | 1726 |
TRIM21,TBC1D4,TBC1D1 |
| 1.055e-02 | -4.55 | chemical homeostasis | biological process | GO:0048878 | 882 | 111 | 16441 | 1675 |
CCDC109B,SLC2A4,EPAS1,ATP2C2,HEXB,TAP1,PKP2,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,SLC9A7,APLP2,ATP6V0B,SESN3,PQLC2,SCNN1A,PLCG2,STEAP2,PIK3CA,ABCA2,CLDN4,TRPC1,CNNM4,CRY2,GOT1,RAB20,IFIT1,ACOX2,TMEM64,SLC39A10,F2R,MYT1,CHP1,MYO5B,SIRT1,CLCN3,CD55,AKT1,ACO1,PRKAR2B,SLC11A2,ATP1B1,RAB38,CD40,ITPR3,ATP13A2,EDNRA,IRS2,ENPP1,ATP1A1,GPRC5B,WFS1,SLC9A6,ATP7B,PEX2,INPP4B,ADIPOR1,F2RL1,ABCA1,PRKAA2,CALB2,MTL5,ABCG2,SLC25A27,GSTP1,SLC9A2,NEO1,CA2,GATA2,SGK3,BAX,SGK1,TMBIM6,MYLIP,SLC12A2,ATP2B1,SLC37A1,MFI2,PIK3R1,ERO1A,EIF5A2,GRIN1,TTC7A,EIF2AK1,NPC2,PDK3,NUBP1,SFXN5,STEAP1,FECH,GNAS,SWAP70,SLC4A4,ACADSB,RAB11FIP2,NR1D2,PRCP,ITPR1,SLC4A3,GPER1,ATP1B3,MCUR1,NDFIP1,JAK3,USF2,CYBRD1,ABCG1,EHD1,EGLN1 |
| 1.059e-02 | -4.55 | soft_tissue-striated_muscle-rhabdomyosarcoma | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma | 610 | 78 | 17775 | 1757 |
CCNE2,LTBP1,ACACB,SSH1,NLRX1,DNAJC3,CAMKK1,TP53,ERBB2,NENF,TMC1,CDKN2C,SIPA1L2,SS18,WDR44,OSBPL3,PIK3CA,CRY2,SCN2A,SLC39A10,NEB,CCDC38,MX1,DOCK4,SPEF2,AKT1,PTGER4,IDH1,DOCK5,COL12A1,ARHGAP35,ATP13A2,EPHA10,CORO1C,PTK7,NRG1,EPB41L4A,LZTS1,SCN5A,KLHL13,ARHGEF11,ESRP1,PYROXD2,COL4A5,CYB561,CRABP2,ADAMTSL4,CD109,IL17RB,IGF1R,ADORA1,LLGL2,TMBIM6,TSPAN13,ZRANB1,PARP9,SOCS5,AMER1,PRICKLE1,DIAPH2,GRTP1,RNPEP,DGKH,FAT4,ETS2,RAB11FIP2,DCK,NETO2,NLRC5,AGBL5,RHOBTB2,YOD1,CENPE,FHL1,MAP3K5,ARHGEF4,TMEM131,USP43 |
| 1.060e-02 | -4.55 | Signaling by NOTCH | REACTOME pathways | R-HSA-157118 | 110 | 20 | 8202 | 867 |
HES1,TNRC6C,ITCH,HDAC11,TP53,FURIN,AGO4,MAML2,RAB6A,NEURL1B,HDAC6,DNER,HDAC9,CCND1,MDK,DTX4,ARRB1,TLE1,HDAC1,NOTCH3 |
| 1.061e-02 | -4.55 | upper_lobe | COSMIC cancer mutations | upper_lobe | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-middle_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-typical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-lower_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-lower_lobe-carcinoid-endocrine_tumour-typical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | myxofibrosarcoma | COSMIC cancer mutations | myxofibrosarcoma | 20 | 6 | 17775 | 1757 |
GNAS,CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-upper_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-upper_lobe-carcinoid-endocrine_tumour-typical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-bronchus-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-atypical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | 20 | 6 | 17775 | 1757 |
GNAS,CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lung-bronchus-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-typical | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | lower_lobe | COSMIC cancer mutations | lower_lobe | 20 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.061e-02 | -4.55 | negative regulation of microtubule polymerization or depolymerization | biological process | GO:0031111 | 31 | 8 | 16441 | 1675 |
GAS2L1,MID1IP1,CKAP2,TBCD,AURKA,HDAC6,CCNB1,APC2 |
| 1.061e-02 | -4.55 | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | 295 | 42 | 17758 | 1761 |
PLA2G4A,LTBP1,COL9A3,TRIM2,KLK10,CKAP2,ITGA6,SOX9,ARL4C,TP53,RAB23,MRAS,GPSM2,S100A2,CYP39A1,MUC16,KCNN4,LMO4,ELF5,TAGLN2,GPR161,LAMP3,CYP26B1,KLK5,CAPN6,TFAP2C,RUNX3,KLK6,NFIB,FZD7,RHEB,NFIX,PTPRF,PLOD2,HOXA9,PGRMC1,BMP1,CLIP4,KLF5,KLK7,L1CAM,RRAGD |
| 1.068e-02 | -4.54 | TTGCCAA,MIR-182 | MSigDB lists | TTGCCAA,MIR-182 | 312 | 44 | 17758 | 1761 |
ARHGEF3,PPP1R2,EPAS1,NUAK1,RET,TEX2,PARM1,GRM5,IRF2BPL,ADD3,UBE2Q2,DOK4,ZFP36,RIMS3,BHLHE41,MITF,SLC44A2,CTTN,CITED2,CNPY3,C9orf72,KDELR1,IGSF3,SYPL1,TRIM8,TMEM68,MMD,TACC1,TP53INP2,RASA1,ARF4,PLCH1,ETS2,HOXA9,CORO1C,LIMK1,SH3BP4,PLD1,ATP1B3,L1CAM,TOB1,RARG,KLF7,DOCK9 |
| 1.068e-02 | -4.54 | Thioredoxin | pfam domains | PF00085 | 31 | 8 | 16629 | 1696 |
DNAJC10,TXN,TMX4,PDIA5,PDIA3,TXNDC11,PDIA6,PDIA4 |
| 1.070e-02 | -4.54 | SMAD3 (SMAD family member 3) | protein interactions | 4088 | 359 | 53 | 16036 | 1726 |
RUNX2,EPAS1,FOXM1,PEX6,GGA1,DCAF7,SOX9,TP53,DHX8,AES,TGFBR1,FBLN1,ETS1,ZFYVE9,LMNA,MECOM,WWP2,WEE1,BMP7,PIK3CA,WWP1,C10orf54,CITED2,TRIM62,MYO5B,EPB41L5,TGIF1,PCDH1,AKT1,NR3C1,NR4A1,ITCH,S100A4,PARP4,RGCC,RUNX3,ERBB2IP,RAB38,FOS,CPTP,RANBP9,PIAS3,PITX2,NCOA3,RBL1,HDAC1,KLF5,IRF7,FHL1,ZMIZ1,RARG,TOB1,DOCK9 |
| 1.074e-02 | -4.53 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2723 | 303 | 17775 | 1757 |
HECA,PPP4R4,HSPG2,VANGL1,ATP8A1,RET,NRG2,CA8,GRM5,CDKN2C,PQLC2,STIM1,RGS3,PRICKLE3,IL31RA,STEAP2,PIK3CA,SNX16,SEMA3G,ARMCX6,TIAM1,TIPARP,ERAP2,SMARCA2,KIFC2,SNTB2,F12,POR,COL12A1,AHRR,PIAS3,SLC25A4,PTER,GNPTAB,LRIG1,NOD2,MRPS28,TANC2,TRAF5,FRMD4A,SCOC,ITGA6,CALB2,TTYH3,FRY,SNX18,MEGF8,BDH1,DAPK1,PCYOX1,CADPS2,ALPK1,CACNA1D,PIKFYVE,NCAM1,MYLIP,DGKG,GPR161,GFPT1,KLK5,MICB,AMER1,ZNF503-AS2,TP53INP2,GNA11,STK17A,PTPRF,CACHD1,NCOA3,AP1AR,ETS2,DCK,MATN2,RAET1L,ITPR1,FAM83D,FGD6,CABIN1,GDF11,DRP2,MAP3K5,PER3,SERPINB1,ADAMTS16,DOCK9,ST14,ACTR8,BROX,CCDC110,IQGAP1,PKP2,PRKACA,ZNF385B,APPBP2,MUC16,ST5,CDH1,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,SCN3A,MYO5B,DOCK4,COG2,FZD4,CAPN6,PLEKHO1,SYNE2,UTRN,PRKCQ,ALCAM,ATP10D,NIN,EPHA10,IRS2,DDOST,INPP4B,PNPLA6,RGS14,ISOC1,ARHGEF3,NKX3-1,ATP9A,ESRP1,DNAH3,TMCC3,PDIA4,SNTA1,PTEN,CD9,ATP8B1,ERBB3,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,LONRF3,FMN1,PIK3R1,GRIN1,CXorf57,PARP4,FURIN,NUCB1,FGFR2,PPM1H,PGM2L1,MELK,OCLN,TLL2,ESYT2,JARID2,UNKL,EXPH5,KIAA1462,EPHA4,ARFGEF1,MPP5,HDAC6,ERP29,SPTB,TRIM68,SIPA1L2,GRHL1,TSPAN6,MKRN3,PAPSS1,ABCA2,POF1B,NTN4,MYH14,TLN2,MYRIP,BTBD3,NEB,ZNF462,MCTP1,TRIM8,CELSR2,ITCH,KLK6,IDH1,PTGFRN,DPYSL3,PLEKHG6,HPSE,MADD,ADIPOR1,SP6,EPB41L4A,RRAGD,ARAP3,LGALS3,HJURP,ETV5,NCKAP1,SAMD9,ANO1,AIM1L,TNS3,FRAS1,KIF13B,WNT3A,NCEH1,ZRANB1,PLCB2,PCDH1,EIF2AK1,SCRIB,HEATR5A,RNF113A,NUBP1,MUM1L1,PRX,GNAS,PRPS2,CTSA,ZDBF2,SHROOM2,JAK3,LMO7,NCKAP5,NF2,FOXM1,TP53,ERBB2,CCDC68,CYP26A1,SYTL2,SS18,ZNF687,ARTN,SETDB2,FRYL,LHX6,FABP6,GOT1,RPN2,TMEM64,PDIA6,SULF2,TMTC1,AKT1,ACO1,ERBB2IP,DOCK5,FANCE,ARHGAP35,PTPRJ,ATP1A1,RBL1,SECTM1,TLE1,SPTBN5,AIFM3,NDST3,ABCA1,BIN1,ANXA3,SORT1,ENO2,ARHGEF11,MACC1,GTF3A,TRMT2B,LBR,SH2D4A,NRP2,SLC9A2,HMGXB4,HDAC9,TOP2A,CARD8,BMP7,LYPD6,GALNS,TOX2,KIAA0319,TRIM21,ABCD1,IQGAP3,ATP2B1,MYO5A,HMMR,DLGAP1,PSMB4,NR4A1,MAML2,COL7A1,FNDC3A,TXNDC11,BANK1,FAT4,SCG2,UACA,ZMIZ1,L1CAM,ARHGEF4,GOLGB1 |
| 1.077e-02 | -4.53 | WOTTON_RUNX_TARGETS_UP | MSigDB lists | WOTTON_RUNX_TARGETS_UP | 20 | 6 | 17758 | 1761 |
CDK18,NCAM1,RNF19B,SERTAD4,CYP1B1,WWP2 |
| 1.077e-02 | -4.53 | TOMLINS_METASTASIS_DN | MSigDB lists | TOMLINS_METASTASIS_DN | 20 | 6 | 17758 | 1761 |
CTSZ,TMEM87B,PVRL2,MESDC2,TMEM131,UBE2J1 |
| 1.077e-02 | -4.53 | ZHAN_MULTIPLE_MYELOMA_SPIKED | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_SPIKED | 20 | 6 | 17758 | 1761 |
GALNT3,CCND1,IFIT3,CTGF,TSPAN7,LGALS3BP |
| 1.077e-02 | -4.53 | GESERICK_TERT_TARGETS_DN | MSigDB lists | GESERICK_TERT_TARGETS_DN | 20 | 6 | 17758 | 1761 |
NFKBIZ,KLF9,NR4A1,ZFP36,FOSB,IER3 |
| 1.080e-02 | -4.53 | CNTFR (ciliary neurotrophic factor receptor) | protein interactions | 1271 | 9 | 4 | 16036 | 1726 |
PLSCR1,LIFR,IL6ST,APPBP2 |
| 1.080e-02 | -4.53 | RABEPK (Rab9 effector protein with kelch motifs) | protein interactions | 10244 | 9 | 4 | 16036 | 1726 |
PRKRA,PIKFYVE,GGA1,POR |
| 1.080e-02 | -4.53 | TBC1D1 (TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1) | protein interactions | 23216 | 9 | 4 | 16036 | 1726 |
ROR1,HSPB1,BARD1,GABARAPL1 |
| 1.080e-02 | -4.53 | WISP2 (WNT1 inducible signaling pathway protein 2) | protein interactions | 8839 | 9 | 4 | 16036 | 1726 |
AMZ2,HDAC1,IGF1R,TRIM68 |
| 1.080e-02 | -4.53 | ETHE1 (ethylmalonic encephalopathy 1) | protein interactions | 23474 | 9 | 4 | 16036 | 1726 |
HDAC1,LRIF1,IDH1,TP53 |
| 1.080e-02 | -4.53 | SLC9A2 (solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2) | protein interactions | 6549 | 9 | 4 | 16036 | 1726 |
RASA1,SLC9A2,PIK3R1,CHP1 |
| 1.080e-02 | -4.53 | MINPP1 (multiple inositol-polyphosphate phosphatase 1) | protein interactions | 9562 | 9 | 4 | 16036 | 1726 |
CD274,CYP1A1,FBXO6,LYPD6 |
| 1.082e-02 | -4.53 | DBB | prosite domains | PS51376 | 2 | 2 | 11866 | 1235 |
BANK1,PIK3AP1 |
| 1.082e-02 | -4.53 | ALPHA_GALACTOSIDASE | prosite domains | PS00512 | 2 | 2 | 11866 | 1235 |
GLA,NAGA |
| 1.085e-02 | -4.52 | stress-activated MAPK cascade | biological process | GO:0051403 | 129 | 22 | 16441 | 1675 |
RIPK2,RPS6KA1,PTGER4,PKN1,DUSP4,ELK1,FOS,TNFRSF19,MAP3K6,MAPK8IP1,MAPKAPK2,RPS6KA2,NOD2,MAP3K9,DUSP10,MAPK11,MDFIC,DAB2IP,MAP3K5,GAB1,SYK,MDFI |
| 1.085e-02 | -4.52 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 196 | 30 | 17758 | 1761 |
LAMP1,SUN2,SNTB2,DNAJB2,TP53,SELL,SLC11A2,KCTD12,TCF7,YES1,FAM101B,FOS,FAM46C,SESN1,SOCS3,TAPBP,SIPA1L2,NR1D2,FAAH,KCNN4,ZFP36,IL6ST,HOXA9,FOSB,ARRB1,FAM102A,PIM1,NR2C1,CTDSP2,ABCG1 |
| 1.085e-02 | -4.52 | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDM_UP | 196 | 30 | 17758 | 1761 |
SUN2,CCDC109B,IL15RA,SH3BGRL,IQGAP1,S100A4,STAU2,PTPN9,FURIN,LITAF,ABCG2,NUSAP1,GPSM2,PKMYT1,CD40,ASB13,ENDOD1,NCOA3,SEMA4D,IL6ST,ZFP36,PAPSS1,SGK1,HDAC1,IRF7,RTKN2,CTTN,ICOSLG,L1CAM,PARP9 |
| 1.085e-02 | -4.52 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | 196 | 30 | 17758 | 1761 |
MX1,GAA,ZWINT,SHMT1,IL15RA,CDKN1C,AASS,STAT4,EZR,PHLPP1,H2AFV,GNA11,SAC3D1,MAPKAPK2,TFAP4,TYMP,TIMP3,CDH1,GNB5,RBL1,SIVA1,SPINT2,INPP4B,TLE1,IRF7,NRG1,PIEZO1,TRAF5,RUSC1,MCCC2 |
| 1.085e-02 | -4.52 | GSE17721_POLYIC_VS_CPG_0.5H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_0.5H_BMDM_DN | 196 | 30 | 17758 | 1761 |
SUN1,PLA2G4A,KCNJ12,TBC1D1,HLA-E,LYRM1,RAB23,C1GALT1C1,ASAH1,NUSAP1,PRSS22,MPP5,TGFBR1,INTS8,ERBB2IP,MCFD2,DHRS3,EFNB1,HMGXB4,DGKE,ALDH3B1,MDM1,RNF128,C19orf66,DCK,FAM20B,PGRMC1,EPHB4,C10orf54,GCNT1 |
| 1.086e-02 | -4.52 | fibrosarcoma | COSMIC cancer mutations | fibrosarcoma | 32 | 8 | 17775 | 1757 |
GNAS,CDKN2C,SS18,CDH1,PTEN,PIK3CA,TP53,IDH1 |
| 1.086e-02 | -4.52 | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | 32 | 8 | 17775 | 1757 |
GNAS,CDKN2C,NF2,PTEN,PIK3R1,PIK3CA,TP53,IDH1 |
| 1.086e-02 | -4.52 | granulosa_cell_tumour | COSMIC cancer mutations | granulosa_cell_tumour | 32 | 8 | 17775 | 1757 |
GNAS,CDKN2C,NF2,PTEN,PIK3R1,PIK3CA,TP53,IDH1 |
| 1.086e-02 | -4.52 | RAS_GTPASE_ACTIV_1 | prosite domains | PS00509 | 14 | 5 | 11866 | 1235 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 1.086e-02 | -4.52 | regulation of stem cell differentiation | biological process | GO:2000736 | 114 | 20 | 16441 | 1675 |
EPB41L5,HES1,SOX9,RGCC,PRICKLE1,TGFBR1,SAV1,LTBP3,DAG1,TEAD3,SIX4,NCOA3,VASN,BMP7,DAB2IP,TACSTD2,TWIST1,C10orf54,WNT3A,TRIM62 |
| 1.086e-02 | -4.52 | regulation of lipase activity | biological process | GO:0060191 | 114 | 20 | 16441 | 1675 |
SORT1,RHOA,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,POR,ARF4,PLIN5,EDNRA,CALM2,PLCG1,ADRBK1,CYR61,FGFR2,ITPR1,PLCB2,RASGRP1 |
| 1.088e-02 | -4.52 | ALK (anaplastic lymphoma receptor tyrosine kinase) | protein interactions | 238 | 67 | 14 | 16036 | 1726 |
MDK,PLCG1,PDLIM3,SHC3,CORO1C,PIK3R1,IRF7,EPHA1,RAD17,MAP3K5,BCAR1,JAK3,PLCB2,SOCS5 |
| 1.088e-02 | -4.52 | BROWNE_HCMV_INFECTION_48HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_DN | 485 | 64 | 17758 | 1761 |
MYL9,LMO7,ACACB,KIAA1462,ADD1,HSPG2,EPAS1,CNOT8,XYLT1,ATP2C2,PDIA5,ERBB2,VASH1,SDC1,SPTB,CCND1,ST5,TSPAN6,ZFP36,AOX1,GLB1L2,MTMR11,S100A13,COL6A2,LOXL2,PKMYT1,RNF19B,SOCS3,ENPP1,WIPI1,MAP2,ITPKA,MAN2B2,GOLIM4,IGFBP6,ALDH6A1,ARHGEF11,CRABP2,SEPP1,PPP2R3A,LGALS3BP,ITGA3,COL6A1,TBCD,MDFIC,MAPK11,SLC16A5,FARP2,DLGAP1,ADAMTS2,FADS2,FBLN5,PCDH1,RAB3B,PLAUR,BTN3A2,EIF2AK1,NFIB,STK17A,RASGRP2,MATN2,GDF11,LTBP2,COL16A1 |
| 1.089e-02 | -4.52 | V$SP1_Q6 | MSigDB lists | V$SP1_Q6 | 237 | 35 | 17758 | 1761 |
UGP2,HOXB7,GGA1,IQGAP1,THRA,NRG2,TIPRL,SH3KBP1,ZFYVE16,APLP2,SNX18,PRICKLE3,CNNM4,CACNA1D,ERBB3,MYLIP,CYP26B1,CPD,DRAP1,NUB1,LYRM1,ELK1,PRKRA,PDIK1L,GNA11,CDK5R1,PIAS3,ONECUT1,TIMP3,CORO1C,SLC9A6,PTK7,AGBL5,PITPNA,KLF11 |
| 1.090e-02 | -4.52 | RUNX2 (runt-related transcription factor 2) | protein interactions | 860 | 54 | 12 | 16036 | 1726 |
HES1,SOX9,TP53,TLE1,HDAC1,WWP1,HDAC6,CCNB1,FOS,ETS1,CDK1,DVL2 |
| 1.090e-02 | -4.52 | GSN (gelsolin) | protein interactions | 2934 | 54 | 12 | 16036 | 1726 |
GAS2L1,CASP3,PLCG1,UBE2Q2,ITCH,PIK3CA,TP53,ARRB1,TMOD2,STK39,BCAR1,CASP4 |
| 1.092e-02 | -4.52 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | 188 | 29 | 17758 | 1761 |
SLC25A24,LGALS3,PLSCR1,GNPDA1,PBK,MBNL3,GTF3A,PIF1,ANLN,BARD1,KIF11,HLA-A,NEO1,ENDOD1,WEE1,PIK3AP1,RANBP1,TOX2,NEK2,PLK4,ALDH7A1,SERPINB6,MRPS28,GEM,NDE1,SGCB,SNX10,TIAM1,E2F8 |
| 1.092e-02 | -4.52 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | 188 | 29 | 17758 | 1761 |
SIGIRR,STAT4,SEPT6,ITGA6,SYNE2,TCF7,PRKCQ,GTF3A,TRIB2,ITPR3,LTBP3,DENND2D,PSIP1,PLCG1,GNB5,NGFRAP1,PASK,FAM102A,FHL1,MYBL1,SLC25A38,MAST4,TBC1D4,TRAF5,CBX7,RASGRP1,PKIA,DOCK9,FAM69A |
| 1.092e-02 | -4.52 | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | 188 | 29 | 17758 | 1761 |
SUN2,GCA,WASF3,B3GNT7,IL15,FLYWCH2,CALB2,PTTG1,MIER3,NDRG2,PRICKLE1,KCTD12,CRABP2,PITX2,CCDC92,CACHD1,NOV,PLEKHH2,RNF128,CYR61,NPNT,SLC16A6,PELI2,FJX1,OVOL1,SNX16,ADIPOR1,ACOX2,OSR1 |
| 1.092e-02 | -4.52 | KASLER_HDAC7_TARGETS_1_UP | MSigDB lists | KASLER_HDAC7_TARGETS_1_UP | 188 | 29 | 17758 | 1761 |
ELK3,TTC39B,PEX6,TESK1,BVES,ZC3H11A,NR4A1,RPS6KA1,UBASH3B,PTGER4,HMG20B,PBX3,SBF1,ZBTB7B,ERP29,NCOA3,SESN3,IDE,SEMA4D,FRYL,OSBPL3,BCL6,RHOBTB2,DUSP10,TMEM37,PIK3CD,NRGN,NCOA2,GM2A |
| 1.092e-02 | -4.52 | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | 87 | 16 | 17758 | 1761 |
TNIP1,SAT1,FURIN,TAP1,BCL2L1,SLC20A1,TNFSF9,CASP4,IER3,RCN1,MAPKAPK2,ETS2,NFKBIA,TPST1,ACSL4,CITED2 |
| 1.097e-02 | -4.51 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | 164 | 26 | 17758 | 1761 |
DDX58,MX1,ACACB,PLSCR1,RIPK2,IL15,HAPLN3,COQ10B,SAT1,HERC5,SAMD9,CD274,HERC6,OTUD1,TMEM54,C19orf66,ZNF214,SECTM1,NFKBIZ,IRF7,IFIT1,OAS3,CMPK2,IFIH1,GLCCI1,FRS3 |
| 1.098e-02 | -4.51 | CTACTGT,MIR-199A | MSigDB lists | CTACTGT,MIR-199A | 172 | 27 | 17758 | 1761 |
SMARCA2,TGIF1,CDK17,CDH22,CPEB4,LRRC1,ATP1B1,SNN,PDIK1L,FOS,GLT8D2,NRP2,AKIRIN1,ARHGAP24,APLP2,SLC4A4,ITGB8,PLOD2,KCNK1,CSNK1G1,HOXA9,PHLPP2,DLG3,CITED2,LIFR,ABCA1,AFAP1 |
| 1.099e-02 | -4.51 | cell adhesion molecule binding | molecular function | GO:0050839 | 184 | 29 | 16491 | 1673 |
PVRL4,TIMP2,FBLN5,NF2,ITGA6,UTRN,SELL,EZR,ERBB2IP,FBLN1,EMP2,CDK5R1,NEO1,EPCAM,NOV,ITGA3,CDH1,CTGF,CYR61,NPNT,PVRL2,PLPP3,CD9,ADAM15,FXYD5,SYK,L1CAM,COL16A1,SMAGP |
| 1.099e-02 | -4.51 | respiratory system development | biological process | GO:0060541 | 207 | 32 | 16441 | 1675 |
GRHL2,EPAS1,THRA,SOX9,CTSZ,GPSM2,SIX4,PDGFA,TNS3,ITGA3,CTGF,ALDH1A3,TMBIM6,PDE4D,MYT1,SPRY2,THRB,SPEF2,ADAMTS2,HES1,RC3H2,NPHP3,SAV1,DAG1,NFIB,CRISPLD2,HS6ST1,FGFR2,PTK7,PLOD3,LTA4H,RARG |
| 1.100e-02 | -4.51 | TDGF1 (teratocarcinoma-derived growth factor 1) | protein interactions | 6997 | 24 | 7 | 16036 | 1726 |
RMND5A,LRIF1,ACVR1C,FBLN1,AIP,RANBP9,WBP5 |
| 1.100e-02 | -4.51 | IL4R (interleukin 4 receptor) | protein interactions | 3566 | 24 | 7 | 16036 | 1726 |
IRS2,IL13RA1,CD40,JAK1,JAK3,INPP5D,SOCS5 |
| 1.100e-02 | -4.51 | KCNA4 (potassium channel, voltage gated shaker related subfamily A, member 4) | protein interactions | 3739 | 24 | 7 | 16036 | 1726 |
DLGAP1,SNTA1,SIRT1,ERBB2IP,DLG3,SAT1,DLG1 |
| 1.104e-02 | -4.51 | anaplastic_large_cell_lymphoma | COSMIC cancer mutations | anaplastic_large_cell_lymphoma | 45 | 10 | 17775 | 1757 |
RHOA,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 1.104e-02 | -4.51 | secretion | biological process | GO:0046903 | 602 | 79 | 16441 | 1675 |
PLA2G4A,ARFGEF1,SYTL4,CACNB4,PDGFB,DDR1,ERP29,SYTL2,CALM2,CCND1,PDGFA,SVBP,RAB15,CTGF,STEAP2,TRPC1,PIK3CD,ARL4D,RAB27B,S100A13,RASGRP1,CHP1,LAMP2,CELSR2,FZD4,RNF19B,OPTN,TRIM9,ALDH5A1,ATP7B,AXL,GNPTAB,RAB11FIP1,NOD2,SYT13,F2RL1,ABCA1,PCSK5,ANXA3,CD63,HABP4,BTN3A1,CALM3,SLC1A3,MERTK,PDIA4,CA2,GATA2,CDK16,LLGL2,RIMS3,KCNN4,EXOC8,CD9,CADPS2,GAD1,SYK,SYTL3,RIMS2,MYO5A,RAB3B,FBLN5,CALM1,FURIN,BTN3A2,SCRIB,STX3,SCRN2,GNAS,SERPINA1,SCG2,SYT7,RAB11FIP2,NR4A3,LTBP2,PLD1,USF2,SNPH,XDH |
| 1.105e-02 | -4.50 | CALCIUM_ION_BINDING | MSigDB lists | CALCIUM_ION_BINDING | 102 | 18 | 17758 | 1761 |
GCA,KCNIP3,MCTP1,REPS2,SLC25A13,S100A4,CALM1,CALM3,NUCB2,HPCAL4,NCS1,CDK5R1,RCN1,CALM2,STIM1,CABP1,S100A13,RASGRP1 |
| 1.106e-02 | -4.50 | GHANDHI_DIRECT_IRRADIATION_DN | MSigDB lists | GHANDHI_DIRECT_IRRADIATION_DN | 32 | 8 | 17758 | 1761 |
PLEKHA6,FZD4,ARHGEF37,PTK7,SYBU,NR3C2,RGMA,MDFI |
| 1.106e-02 | -4.50 | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | MSigDB lists | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 32 | 8 | 17758 | 1761 |
MX1,PLSCR1,IFITM3,TAP1,IRF7,IFIT3,CKAP4,LGALS3BP |
| 1.106e-02 | -4.50 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 8 | 17758 | 1761 |
PGM1,IGF1R,TNIP1,ZNF395,P4HA2,AK4,EGLN3,EGLN1 |
| 1.106e-02 | -4.50 | MODULE_366 | MSigDB lists | MODULE_366 | 32 | 8 | 17758 | 1761 |
SHMT1,OSBPL3,EPHA1,PLXNA1,ZMYM1,RAP1GAP,DHRS3,CPPED1 |
| 1.108e-02 | -4.50 | cellular glucan metabolic process | biological process | GO:0006073 | 57 | 12 | 16441 | 1675 |
CALM2,PGM1,GAA,PRKAG2,PPP1R2,UGP2,AKT1,IL6ST,CALM1,CALM3,PGM2L1,PHKA2 |
| 1.108e-02 | -4.50 | chondroitin sulfate metabolic process | biological process | GO:0030204 | 57 | 12 | 16441 | 1675 |
B3GALT6,CHSY3,HSPG2,XYLT2,IMPAD1,SDC4,XYLT1,HEXB,DSE,ARSB,SDC1,CHPF |
| 1.108e-02 | -4.50 | glucan metabolic process | biological process | GO:0044042 | 57 | 12 | 16441 | 1675 |
CALM2,PGM1,GAA,PRKAG2,PPP1R2,UGP2,AKT1,IL6ST,CALM1,CALM3,PGM2L1,PHKA2 |
| 1.111e-02 | -4.50 | autonomic_ganglia-paraspinal-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-paraspinal-neuroblastoma | 26 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,PIK3R1,RET,PIK3CA |
| 1.111e-02 | -4.50 | paraspinal | COSMIC cancer mutations | paraspinal | 26 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,RET,PIK3R1,PIK3CA |
| 1.111e-02 | -4.50 | autonomic_ganglia-mediastinum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-mediastinum-neuroblastoma | 26 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,RET,PIK3R1,PIK3CA |
| 1.111e-02 | -4.50 | autonomic_ganglia-abdomen-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-abdomen-neuroblastoma | 26 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,RET,PIK3R1,PIK3CA |
| 1.111e-02 | -4.50 | breast-hyperplasia-atypical_lobular_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_lobular_hyperplasia | 26 | 7 | 17775 | 1757 |
ERBB2,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 1.111e-02 | -4.50 | atypical_lobular_hyperplasia | COSMIC cancer mutations | atypical_lobular_hyperplasia | 26 | 7 | 17775 | 1757 |
ERBB2,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 1.111e-02 | -4.50 | Ras activation uopn Ca2+ infux through NMDA receptor | REACTOME pathways | R-HSA-442982 | 19 | 6 | 8202 | 867 |
CALM3,CALM2,GRIN2D,RASGRF1,CALM1,GRIN1 |
| 1.117e-02 | -4.49 | MODULE_45 | MSigDB lists | MODULE_45 | 565 | 73 | 17758 | 1761 |
S100A11,RPS6KA1,THRA,TSC22D3,INPP5D,TAP1,NRG2,IL13RA1,IL27RA,TP53I11,SDC1,CARD10,CYP26A1,IER3,DAPK2,TYMP,SP100,TRANK1,SH3BP1,LMO4,PLCG2,BCL6,ANKRD12,IFIT1,PIK3CD,PTPRE,RASGRP1,CYP1B1,LAMP2,CPD,CD55,S100A4,PTPN9,CDA,ARHGDIB,CCNF,CASP4,SECTM1,BMP1,NRGN,ABCA1,GRN,PCOLCE,ITGA6,ARL4C,ASAH1,SELL,TRIB2,PKN1,M6PR,LLGL2,CTSC,SLC16A6,CADPS2,PIM1,PLCB2,SYK,PLSCR1,MMD,MPP1,STAT4,BTN3A2,TCF7,IFIT3,CDK5R1,SLC6A6,SERPINA1,SEMA4D,NMI,ZMIZ1,JAK3,SERPINB1,XDH |
| 1.118e-02 | -4.49 | positive regulation of T cell proliferation | biological process | GO:0042102 | 85 | 16 | 16441 | 1675 |
HES1,CD55,RIPK2,IL15,HLA-E,PRKCQ,IL18,CD274,TNFSF9,EFNB1,HLA-A,IL6ST,IGFBP2,ICOSLG,JAK3,SYK |
| 1.118e-02 | -4.49 | regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0051090 | 363 | 51 | 16441 | 1675 |
DDX58,SIGIRR,ANXA3,PINK1,THRA,DAP,PSMD10,CAMK1D,FZD6,WWP2,CTNNBIP1,SP100,IGF1R,PTEN,BMP7,SIVA1,SGK3,SGK1,TRIM21,DAB2IP,MAPK11,TWIST1,PIM1,WNT3A,SYK,TRIM62,DVL2,CHP1,CYP1B1,CTH,SIRT1,TRIM8,RIPK2,AKT1,FZD4,ITCH,RGCC,PRKCQ,ERBB2IP,SAV1,GTF2A2,CD40,FOS,PLPP3,WFS1,NFKBIA,NOD2,NLRC5,ARRB1,TRAF5,EGLN1 |
| 1.119e-02 | -4.49 | apical plasma membrane | cellular component | GO:0016324 | 277 | 40 | 17570 | 1756 |
ERBB2,SYTL4,EMP2,ANO1,FZD6,EPCAM,SCNN1A,PTEN,KCNN4,CD9,CLDN4,ATP8B1,IGFBP2,ERBB3,PDE4D,RAB27B,SLC12A2,MYRIP,AMOTL2,CRB3,RAPGEF2,EZR,SLC11A2,ATP1B1,STX3,DUOX1,ATP1A1,TJP3,KCNK1,SHROOM3,STK26,TMEM30A,NRG1,STK39,MAL2,PLD1,SHROOM2,LZTS1,OCLN,PROM2 |
| 1.127e-02 | -4.49 | condensed chromosome kinetochore | cellular component | GO:0000777 | 94 | 17 | 17570 | 1756 |
PLK1,REC8,ZWINT,CENPA,SPC25,HJURP,SEPT6,NDC80,NUF2,CCNB1,CENPN,DCTN6,NEK2,BUB1,CENPE,NDE1,NUP85 |
| 1.128e-02 | -4.48 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | 45 | 10 | 17758 | 1761 |
CCNE2,KLK10,TIMP3,CDKN1C,ST14,CSF1,CDH3,TP53I11,BARD1,IFI6 |
| 1.129e-02 | -4.48 | Wnt Signaling Pathway NetPath | WikiPathways | WP363 | 115 | 22 | 4455 | 516 |
RHOA,RUNX2,AKT1,FZD4,BCL9,SOX9,CDK1,MAPK8IP1,FZD6,FZD7,CXXC4,CCND1,CTNNBIP1,CDH1,ANKRD6,NKD1,TFAP2A,DLG1,ARRB1,FZD5,WNT3A,DVL2 |
| 1.130e-02 | -4.48 | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | 26 | 7 | 17758 | 1761 |
EZR,ARHGDIB,HMGN3,S100A11,SIRPA,ARL4C,PTGER4 |
| 1.130e-02 | -4.48 | IKEDA_MIR30_TARGETS_DN | MSigDB lists | IKEDA_MIR30_TARGETS_DN | 26 | 7 | 17758 | 1761 |
PRICKLE1,STK39,NCAM1,PPP1R14C,MMD,ANO4,PANK1 |
| 1.130e-02 | -4.48 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | 26 | 7 | 17758 | 1761 |
HMMR,KIF23,CENPA,TXN,SPC25,ASPM,KIF14 |
| 1.130e-02 | -4.48 | EINAV_INTERFERON_SIGNATURE_IN_CANCER | MSigDB lists | EINAV_INTERFERON_SIGNATURE_IN_CANCER | 26 | 7 | 17758 | 1761 |
MX1,TGIF1,IFIT1,IFIT3,SP100,IFI6,APOBEC3G |
| 1.130e-02 | -4.48 | BIOCARTA_RACCYCD_PATHWAY | MSigDB lists | BIOCARTA_RACCYCD_PATHWAY | 26 | 7 | 17758 | 1761 |
CDKN1B,CCND1,RHOA,AKT1,NFKBIA,PIK3R1,PIK3CA |
| 1.130e-02 | -4.48 | JI_METASTASIS_REPRESSED_BY_STK11 | MSigDB lists | JI_METASTASIS_REPRESSED_BY_STK11 | 26 | 7 | 17758 | 1761 |
LTBP1,LIMCH1,GDF15,DUSP4,EPAS1,F2RL1,CYP1B1 |
| 1.130e-02 | -4.48 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | 26 | 7 | 17758 | 1761 |
CDKN1B,CCND1,RUNX2,SERPINA1,FAS,BCL6,MAPK12 |
| 1.130e-02 | -4.48 | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN | 26 | 7 | 17758 | 1761 |
GRN,TOP2A,KLK7,KLK10,ZWINT,ITGA6,LGALS3BP |
| 1.130e-02 | -4.48 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | 26 | 7 | 17758 | 1761 |
B3GALT6,HS6ST1,HS3ST3B1,NDST3,XYLT2,XYLT1,GLCE |
| 1.131e-02 | -4.48 | secretion by cell | biological process | GO:0032940 | 499 | 67 | 16441 | 1675 |
ARFGEF1,SYTL4,PDGFB,ERP29,SYTL2,PDGFA,CALM2,SVBP,RAB15,CTGF,STEAP2,PIK3CD,ARL4D,RAB27B,S100A13,RASGRP1,CHP1,LAMP2,FZD4,RNF19B,OPTN,TRIM9,ALDH5A1,AXL,GNPTAB,RAB11FIP1,NOD2,SYT13,F2RL1,ABCA1,PCSK5,ANXA3,CD63,HABP4,BTN3A1,CALM3,SLC1A3,MERTK,PDIA4,LLGL2,GATA2,CDK16,RIMS3,CD9,EXOC8,CADPS2,GAD1,SYTL3,SYK,RIMS2,MYO5A,RAB3B,CALM1,FURIN,BTN3A2,SCRIB,STX3,SCRN2,GNAS,SERPINA1,SYT7,RAB11FIP2,SCG2,NR4A3,PLD1,LTBP2,SNPH |
| 1.131e-02 | -4.48 | sensory organ development | biological process | GO:0007423 | 499 | 67 | 16441 | 1675 |
GRHL2,NF2,RET,ERBB2,OSR2,TMC1,PLS3,RCN1,CYP1A1,ALDH1A3,MITF,DLG1,CDKN1B,TWIST1,ECE1,DVL2,CYP1B1,FZD4,PRKRA,ABR,ARHGAP35,BFSP1,PTK7,TRAF3IP1,LRIG1,NKD1,HDAC1,HOXC13,CTHRC1,CDKN1C,SDC4,SOX9,SLC25A27,TGFBR1,PLPPR4,MERTK,PPP2R3A,FZD6,SIX4,MDM1,GATA2,BMP7,CST3,FJX1,BAX,TFAP2A,ATP8B1,WNT3A,SPRY2,HES1,TGIF1,SCRIB,BCAR3,PITX2,MAPKAPK2,FAT4,TWSG1,ACVRL1,FGFR2,TBX18,NR4A3,GDF11,SOX8,OSR1,FZD5,SHROOM2,RARG |
| 1.132e-02 | -4.48 | CROMER_METASTASIS_DN | MSigDB lists | CROMER_METASTASIS_DN | 80 | 15 | 17758 | 1761 |
DDB2,PRODH,KLK10,ITGA3,EPAS1,S100A11,FXYD3,SDC4,BMP1,KLF5,MAST4,GSTP1,CARD10,LMNA,IGSF3 |
| 1.132e-02 | -4.48 | PID_MET_PATHWAY | MSigDB lists | PID_MET_PATHWAY | 80 | 15 | 17758 | 1761 |
PLCG1,RHOA,PTPRJ,AKT1,CDH1,INPP5D,PIK3R1,PIK3CA,ARF6,BCAR1,ETS1,GAB1,RANBP9,SH3KBP1,ARHGEF4 |
| 1.134e-02 | -4.48 | PDGF | smart domains | SM00141 | 9 | 4 | 9131 | 997 |
PDGFA,PGF,PDGFC,PDGFB |
| 1.135e-02 | -4.48 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | 835 | 103 | 17758 | 1761 |
DYNLRB1,SLC2A4,IL15RA,CAST,FTH1,SNN,AIFM2,KBTBD11,ERP29,LTBP3,GRHL1,EFR3A,ARHGEF37,SIVA1,IL31RA,N4BP3,AOX1,BCL6,TMEM143,DAB2IP,ECE1,TIPARP,SNX10,S100A13,TNIP1,NFE2L1,GLO1,ARFRP1,PRKRA,IDH1,MYL12A,TYSND1,ARF4,GABARAPL1,MID1IP1,GPRC5B,AGPAT2,ABHD12,PEX2,SIPA1L1,TLE1,EIF4EBP2,KLF11,EFNA5,NFKBIZ,MLKL,RMND5A,SORT1,HJURP,SCOC,ALDH6A1,DAP,CENPI,C6orf106,ASAH1,ADCK5,SEPP1,LGALS3BP,BMP2K,LMNA,TMCC3,ELF3,PDIA4,IRF2BPL,IL17RB,CST3,TBCD,PCYOX1,ADCK2,FAM102A,ECI2,SELK,NUP85,FAH,SYPL1,FADS2,OPLAH,TGIF1,MRPS33,MMD,PQLC3,ADCK3,MGAT4B,GYLTL1B,NPHP3,BCAR1,RNPEP,NFIB,PRX,CYB5A,BCAR3,SCARB2,MAMDC4,FAM64A,CGREF1,AGBL5,ATP1B3,MAL2,TMEM120A,WDR62,PLOD3,TMEM131,XDH |
| 1.135e-02 | -4.48 | arachidonic acid metabolic process | biological process | GO:0019369 | 64 | 13 | 16441 | 1675 |
PLA2G4A,MAPKAPK2,FAM213B,CYP1A1,FAAH,CYP2S1,CYP2U1,LTA4H,CYP4F3,PTGES,CYP1B1,GPX4,ABCC1 |
| 1.135e-02 | -4.48 | cellular component disassembly involved in execution phase of apoptosis | biological process | GO:0006921 | 64 | 13 | 16441 | 1675 |
TOP2A,CASP3,CDH1,ADD1,H1F0,DNM1L,ACVR1C,STK26,PRKCQ,GPER1,BCAP31,LMNA,OCLN |
| 1.139e-02 | -4.48 | cellular response to topologically incorrect protein | biological process | GO:0035967 | 122 | 21 | 16441 | 1675 |
GFPT1,SEC61B,ADD1,AMFR,DNAJC3,ERO1A,PDIA5,DNAJB11,HDAC6,DNAJB9,LMNA,CCND1,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 1.139e-02 | -4.48 | regulation of peptidase activity | biological process | GO:0052547 | 397 | 55 | 16441 | 1675 |
CASP3,PINK1,PCOLCE,NKX3-1,SERPINE2,RPS6KA1,DAP,CAST,PSME2,PTTG1,RET,PSME1,FBLN1,BCAP31,CD109,TFAP4,APLP2,CARD8,CTGF,CYR61,CTSC,CST3,DAPK1,BAX,CDKN1B,SORL1,EGLN3,WNT3A,CDKN2D,F2R,SIRT1,TIMP2,RHOA,AKT1,ACVR1C,PLAUR,CASP9,FURIN,COL7A1,SLC11A2,POR,FAS,TIMP3,SERPINA1,NGFRAP1,SPINT2,ARRB1,SERPINB6,SERPINI1,GPER1,MAP3K5,SERPINB1,IFI6,XDH,MAPK12 |
| 1.142e-02 | -4.47 | ATGTAGC,MIR-221,MIR-222 | MSigDB lists | ATGTAGC,MIR-221,MIR-222 | 133 | 22 | 17758 | 1761 |
SUN2,BMF,CDKN1C,EIF5A2,SYBU,MIER3,FNDC3A,VASH1,FOS,ETS1,ARF4,TIMP3,ATP1A1,ETS2,CDK19,RIMS3,AMMECR1,UBE2J1,IRF2,CDKN1B,MYLIP,LIFR |
| 1.145e-02 | -4.47 | mannosyl-glycoprotein N-acetylglucosaminyltransferases | BIOCYC pathways | META_PWY-7426 | 8 | 4 | 907 | 115 |
MAN2A2,MGAT4A,MGAT5,MGAT4B |
| 1.146e-02 | -4.47 | cell activation | biological process | GO:0001775 | 664 | 86 | 16441 | 1675 |
PLA2G4A,MYL9,IL15,CAST,TP53,IL18,ITPR2,SLC7A2,PDGFB,TNFSF9,PDGFA,CALM2,PLCG2,DLG1,BCL6,PIK3CA,PIK3CD,F2R,S100A13,RASGRP1,LAMP2,RIPK2,AKT1,PTGER4,CR2,PRKCQ,CD40,ITPR3,MYL12A,FZD7,CMTM7,DDOST,ABHD12,HOXA9,AXL,HSPB1,F2RL1,ANXA3,RUNX2,CD63,HLA-E,HABP4,DGKQ,BTN3A1,CALM3,TGFBR1,MERTK,IL18R1,FZD6,HDAC9,GATA2,KIF13B,CST3,CD9,BAX,WNT3A,DGKG,ULBP2,SYK,RHOA,PLSCR1,MICB,CALM1,RC3H2,PIK3R1,RGCC,C1GALT1C1,BCAR1,GNA11,DGKE,RASGRP2,FAS,DGKH,GNAS,ONECUT1,SWAP70,BANK1,SERPINA1,CSF1,DHRS2,ITPR1,NR4A3,ARRB1,FZD5,ICOSLG,JAK3 |
| 1.147e-02 | -4.47 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 256 | 38 | 16441 | 1675 |
DLGAP5,PSME2,CUL4B,CTDSPL,TP53,PSMD10,PSME1,CCNB1,FANCI,IER3,CCND1,E2F7,CYP1A1,PSMD1,PTEN,DACT1,KIF14,CDKN1B,BUB1,PIM1,CTDSP2,PLK1,AKT1,PSMB4,CDC20,RGCC,PRKCQ,ANLN,PSMA4,CDK1,JADE1,TJP3,CDCA5,FHL1,CENPE,UBE2C,ESPL1,PKIA |
| 1.149e-02 | -4.47 | regulation of ion transmembrane transporter activity | biological process | GO:0032412 | 176 | 28 | 16441 | 1675 |
PPIF,RASGRF1,TCAF1,FXYD3,CALM1,UTRN,CALM3,ATP1B1,ANO9,PRKACA,CACNB4,WWP2,CALM2,GNB5,STIM1,CABP1,PLCG2,NETO2,DAPK1,FXYD5,CAB39,STK39,PDE4D,ATP1B3,FHL1,CACNA1D,MYO5A,CHP1 |
| 1.149e-02 | -4.47 | regulation of cell size | biological process | GO:0008361 | 176 | 28 | 16441 | 1675 |
SEMA6B,CLCN3,ADD1,AKT1,RET,ANO6,EZR,PLXNA1,CRABP2,CDK5R1,SEMA4D,PTEN,DPYSL2,LIMK1,MEGF8,KCNN4,NRG1,EFNA5,TNFRSF12A,CTTN,SEMA3G,IQGAP3,WNT3A,SEMA3A,SLC12A2,L1CAM,RARG,SEMA3B |
| 1.151e-02 | -4.46 | EFh | smart domains | SM00054 | 143 | 25 | 9131 | 997 |
MYL9,GCA,SLC25A24,KCNIP3,SLC25A13,CALM1,CALB2,CALM3,EFHD2,NUCB2,MYL12A,HPCAL4,NCS1,RASGRP2,PLS3,CALM2,RCN1,NUCB1,PLCH1,DUOX1,CABP1,CGREF1,DGKG,CAPN1,CHP1 |
| 1.155e-02 | -4.46 | MODULE_13 | MSigDB lists | MODULE_13 | 504 | 66 | 17758 | 1761 |
SPC25,EPAS1,ST14,CD82,INPP5D,TGOLN2,ITPR2,VASH1,CARD10,DAPK2,CDKN2C,ST5,ARTN,SH3BP1,ANKRD12,TUBG1,IFIT1,TECR,PLK1,PPIF,PTPN9,UTRN,KIF1C,CD40,BMP1,RAP1GAP,PINK1,HAL,RASSF7,CALB2,C6orf106,EFNB1,SAC3D1,RABGGTA,M6PR,ADRBK1,ITGA3,LYPD3,LLGL2,CTSC,TBCD,BDH1,ARVCF,ADAM15,CLIP2,GPR161,RIMS2,PCBP3,TCF7,CDK5R1,MAPK8IP1,MMP15,TIMP3,SLC6A6,SEMA4D,ACVRL1,CSF1,S100A5,SLC4A3,CCDC69,PLIN3,ESPL1,AFAP1,EHD1,CD33,XDH |
| 1.156e-02 | -4.46 | activation of innate immune response | biological process | GO:0002218 | 248 | 37 | 16441 | 1675 |
DDX58,RPS6KA1,PSME2,CALM3,PSMD10,PSME1,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,PIK3AP1,PLCG2,MAPK11,LGMN,SCARA3,CNPY3,SYK,PSMB4,TNIP1,RIPK2,ITCH,CALM1,DUSP4,ITPR3,ELK1,FOS,PSMA4,CTSL,MAPKAPK2,PELI2,NFKBIA,ITPR1,NOD2,IRF7,IFIH1,TMEM173 |
| 1.157e-02 | -4.46 | CACTGTG,MIR-128A,MIR-128B | MSigDB lists | CACTGTG,MIR-128A,MIR-128B | 322 | 45 | 17758 | 1761 |
LTBP1,FRMD4A,ARHGEF11,VANGL1,DCAF7,CTDSPL,PDIA5,TGFBR1,NEO1,CCDC92,SS18,WEE1,EFR3A,CABP1,RIMS3,NEK2,WNT3A,CITED2,GAD1,CTDSP2,DVL2,CCDC88A,IGSF3,MDFI,CPD,SIRT1,SMARCA2,PTPN9,PIK3R1,MGAT4B,FURIN,ZKSCAN2,PELI3,GTF2A2,SP4,DCP2,RND3,PTER,PLK2,CORO1C,CSF1,RAB11FIP1,FAM195A,SH3BGRL2,NXT2 |
| 1.158e-02 | -4.46 | NUDT22 (nudix hydrolase 22) | protein interactions | 84304 | 2 | 2 | 16036 | 1726 |
AES,LHX6 |
| 1.158e-02 | -4.46 | TPO (thyroid peroxidase) | protein interactions | 7173 | 2 | 2 | 16036 | 1726 |
DUOX1,TXNDC11 |
| 1.158e-02 | -4.46 | SIGLEC9 (sialic acid binding Ig-like lectin 9) | protein interactions | 27180 | 2 | 2 | 16036 | 1726 |
NCAM1,LGALS3BP |
| 1.158e-02 | -4.46 | LIF (leukemia inhibitory factor) | protein interactions | 3976 | 2 | 2 | 16036 | 1726 |
LIFR,IL6ST |
| 1.158e-02 | -4.46 | Ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide) | protein interactions | 22630 | 2 | 2 | 16036 | 1726 |
RGS3,CALM1 |
| 1.158e-02 | -4.46 | IL17B (interleukin 17B) | protein interactions | 27190 | 2 | 2 | 16036 | 1726 |
IL17RB,ENO2 |
| 1.158e-02 | -4.46 | Cbl (Cbl proto-oncogene, E3 ubiquitin protein ligase) | protein interactions | 500985 | 2 | 2 | 16036 | 1726 |
F2RL1,SH3KBP1 |
| 1.158e-02 | -4.46 | SORCS1 (sortilin-related VPS10 domain containing receptor 1) | protein interactions | 114815 | 2 | 2 | 16036 | 1726 |
SORT1,FURIN |
| 1.158e-02 | -4.46 | GPER1 (G protein-coupled estrogen receptor 1) | protein interactions | 2852 | 2 | 2 | 16036 | 1726 |
PTEN,PTTG1 |
| 1.158e-02 | -4.46 | ADGRA3 (adhesion G protein-coupled receptor A3) | protein interactions | 166647 | 2 | 2 | 16036 | 1726 |
DLG1,RYK |
| 1.158e-02 | -4.46 | CYP2A6 (cytochrome P450, family 2, subfamily A, polypeptide 6) | protein interactions | 1548 | 2 | 2 | 16036 | 1726 |
POR,CYB5A |
| 1.158e-02 | -4.46 | fzr1 (fizzy/cell division cycle 20 related 1) | protein interactions | 380351 | 2 | 2 | 16036 | 1726 |
CCNB1,UBE2C |
| 1.158e-02 | -4.46 | CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2) | protein interactions | 1544 | 2 | 2 | 16036 | 1726 |
POR,CYB5A |
| 1.158e-02 | -4.46 | PPEF2 (protein phosphatase, EF-hand calcium binding domain 2) | protein interactions | 5470 | 2 | 2 | 16036 | 1726 |
CALM3,CALM1 |
| 1.158e-02 | -4.46 | NEIL3 (nei-like DNA glycosylase 3) | protein interactions | 55247 | 2 | 2 | 16036 | 1726 |
TWIST1,TP53 |
| 1.158e-02 | -4.46 | CYP4A11 (cytochrome P450, family 4, subfamily A, polypeptide 11) | protein interactions | 1579 | 2 | 2 | 16036 | 1726 |
CYB5A,PIK3R1 |
| 1.158e-02 | -4.46 | Traf3 (TNF receptor-associated factor 3) | protein interactions | 22031 | 2 | 2 | 16036 | 1726 |
CD40,TNFRSF19 |
| 1.158e-02 | -4.46 | IFIT1B (interferon-induced protein with tetratricopeptide repeats 1B) | protein interactions | 439996 | 2 | 2 | 16036 | 1726 |
IFIT1,IFIT3 |
| 1.158e-02 | -4.46 | AP5Z1 (adaptor-related protein complex 5, zeta 1 subunit) | protein interactions | 9907 | 2 | 2 | 16036 | 1726 |
IRF2,MDFI |
| 1.158e-02 | -4.46 | IL31RA (interleukin 31 receptor A) | protein interactions | 133396 | 2 | 2 | 16036 | 1726 |
LIFR,IL6ST |
| 1.158e-02 | -4.46 | Ppp1cc (protein phosphatase 1, catalytic subunit, gamma isoform) | protein interactions | 19047 | 2 | 2 | 16036 | 1726 |
CALM1,SH3KBP1 |
| 1.158e-02 | -4.46 | ADGRA2 (adhesion G protein-coupled receptor A2) | protein interactions | 25960 | 2 | 2 | 16036 | 1726 |
DLG1,RYK |
| 1.158e-02 | -4.46 | COL5A2 (collagen, type V, alpha 2) | protein interactions | 1290 | 2 | 2 | 16036 | 1726 |
DDR1,BMP1 |
| 1.158e-02 | -4.46 | ZBTB37 (zinc finger and BTB domain containing 37) | protein interactions | 84614 | 2 | 2 | 16036 | 1726 |
HSPB1,SH3BP4 |
| 1.158e-02 | -4.46 | PDE5A (phosphodiesterase 5A, cGMP-specific) | protein interactions | 8654 | 2 | 2 | 16036 | 1726 |
CASP3,PRKG1 |
| 1.158e-02 | -4.46 | RGPD4 (RANBP2-like and GRIP domain containing 4) | protein interactions | 285190 | 2 | 2 | 16036 | 1726 |
PLK1,LGR4 |
| 1.158e-02 | -4.46 | ZNF239 (zinc finger protein 239) | protein interactions | 8187 | 2 | 2 | 16036 | 1726 |
CEP70,LMNA |
| 1.158e-02 | -4.46 | NAT16 (N-acetyltransferase 16 (GCN5-related, putative)) | protein interactions | 375607 | 2 | 2 | 16036 | 1726 |
RIPK2,NOD2 |
| 1.158e-02 | -4.46 | CD207 (CD207 molecule, langerin) | protein interactions | 50489 | 2 | 2 | 16036 | 1726 |
SUSD3,SCARA3 |
| 1.158e-02 | -4.46 | Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) | protein interactions | 23971 | 2 | 2 | 16036 | 1726 |
PAPSS2,PAPSS1 |
| 1.158e-02 | -4.46 | Wasl (Wiskott-Aldrich syndrome-like (human)) | protein interactions | 73178 | 2 | 2 | 16036 | 1726 |
BIN1,SH3KBP1 |
| 1.158e-02 | -4.46 | V$SRY_02 | MSigDB lists | V$SRY_02 | 238 | 35 | 17758 | 1761 |
MRC2,NFKBIE,KLHL13,TSC22D3,DHRS3,TNFRSF19,SIX4,ZNF385B,CCDC92,FOXP2,TFAP4,RCN1,GATA2,LMO4,KLF3,MITF,TACSTD2,CLIP2,TIAM1,NR4A1,PIK3R1,NFE2L1,RGAG1,PTGFRN,NFIB,NFIX,XKRX,FGFR2,KBTBD2,PELI2,NR4A3,LEMD1,IFIH1,NR3C2,KLF7 |
| 1.159e-02 | -4.46 | Polo-like kinase signaling events in the cell cycle | Pathway Interaction DB | plk_pathway | 4 | 3 | 2227 | 331 |
PLK1,PLK2,PLK4 |
| 1.160e-02 | -4.46 | Kinesin | pfam domains | PF00225 | 44 | 10 | 16629 | 1696 |
KIF5B,KIF20A,KIFC2,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 1.160e-02 | -4.46 | KATSANOU_ELAVL1_TARGETS_DN | MSigDB lists | KATSANOU_ELAVL1_TARGETS_DN | 141 | 23 | 17758 | 1761 |
SHMT1,COL6A2,DEPDC1,EPS8,MYBL2,TTC7A,PKMYT1,MNS1,STEAP1,TFAP4,ETS2,NPNT,STK38,CDCA7L,COL6A1,CLIP4,DUSP10,CDH3,SGK1,ALDH7A1,UBE2C,ETV4,TIAM1 |
| 1.162e-02 | -4.46 | GSE20715_0H_VS_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_DN | 197 | 30 | 17758 | 1761 |
CCNE2,GCLM,SEC61B,CENPA,SPC25,KIF20A,GCLC,PBK,DHX8,NUSAP1,ANLN,PHLDA1,MAP3K6,CDK1,TNFSF9,DNAJB9,ELF3,PRIM1,SOCS3,TOP2A,RBM47,RANBP1,DAPK1,CLIP4,BUB1,MANF,SPCS3,UBE2C,HSPB1,WBP5 |
| 1.164e-02 | -4.45 | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | 73 | 14 | 17758 | 1761 |
ANXA3,ADD3,SP100,IGFBP6,IQGAP1,EPHA4,HMG20B,LOXL2,SLC12A2,EMP2,DDR1,COL16A1,HDAC9,IER3 |
| 1.164e-02 | -4.45 | SU_TESTIS | MSigDB lists | SU_TESTIS | 73 | 14 | 17758 | 1761 |
HMMR,IDE,NF2,ITCH,NEK2,AURKA,SFMBT1,ZNF165,BUB1,RAD17,CCNB1,CCNB2,CDK1,NXT2 |
| 1.164e-02 | -4.45 | SANA_RESPONSE_TO_IFNG_UP | MSigDB lists | SANA_RESPONSE_TO_IFNG_UP | 73 | 14 | 17758 | 1761 |
DTX3L,MX1,HLA-B,HLA-E,NLRC5,MLKL,CD274,HLA-C,IFIH1,ETV7,APOL2,LGALS3BP,HLA-A,PARP9 |
| 1.164e-02 | -4.45 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 73 | 14 | 17758 | 1761 |
CCDC92,SUN2,GPRC5B,FRYL,RAPGEF2,PHLPP2,IL6ST,DLG1,FBXO9,ERBB2IP,DNAJB14,BTBD3,NCS1,NIPA1 |
| 1.168e-02 | -4.45 | - | gene3d domains | 3.40.50.850 | 2 | 2 | 9988 | 1080 |
ISOC2,ISOC1 |
| 1.168e-02 | -4.45 | - | gene3d domains | 3.90.1170.50 | 2 | 2 | 9988 | 1080 |
XDH,AOX1 |
| 1.168e-02 | -4.45 | - | gene3d domains | 3.30.365.10 | 2 | 2 | 9988 | 1080 |
AOX1,XDH |
| 1.168e-02 | -4.45 | - | gene3d domains | 1.10.150.120 | 2 | 2 | 9988 | 1080 |
AOX1,XDH |
| 1.169e-02 | -4.45 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | molecular function | GO:0000981 | 606 | 79 | 16491 | 1673 |
FOXO6,GRHL2,EPAS1,FOXM1,THRA,TP53,OSR2,HSF2,GRHL1,MITF,FOSB,ELF5,BCL6,IRF2,TWIST1,MYBL1,ETV4,NR2C1,THRB,KCNIP3,FOXJ2,NFE2L1,TFAP2C,SP4,ARHGAP35,NFIX,KLF12,PRDM5,OVOL1,KLF5,IRF7,KLF11,E2F8,MAFF,HOXC13,NKX3-1,RUNX2,SOX9,ETV5,PBX3,ETS1,SIX4,ELF3,TFAP4,E2F7,GATA2,BHLHE41,TFAP2A,ETV7,NFE2L3,TGIF1,HES1,ELK3,PLSCR1,NR3C1,NR4A1,MYBL2,ZKSCAN2,PPARA,RUNX3,ELK1,FOS,NFIB,FOXL1,FOXD2,PITX2,ONECUT1,NCOA3,ETS2,NR1D2,NR4A3,NR4A2,HMGA1,GPER1,SOX8,USF2,RARG,AHR,JARID2 |
| 1.169e-02 | -4.45 | positive regulation of cell-cell adhesion | biological process | GO:0022409 | 232 | 35 | 16441 | 1675 |
IL15,ITGA6,HLA-E,IL18,CD274,TNFSF9,EFNB1,HLA-A,IL6ST,BMP7,PIK3CA,IGFBP2,CITED2,WNT3A,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,AKT1,RIPK2,PIK3R1,PRKCQ,YES1,CD83,PLPP3,TBX18,NR4A3,NOD2,PIEZO1,ICOSLG,RAP1GAP,JAK3,L1CAM |
| 1.170e-02 | -4.45 | phosphoric ester hydrolase activity | molecular function | GO:0042578 | 357 | 50 | 16491 | 1673 |
MTM1,DLGAP5,SSH1,PPM1J,UBASH3B,TMEM55B,INPP5D,CTDSPL,PDIA3,PHLPP1,LPIN3,SBF1,PLPPR4,ADORA1,PTEN,ALPP,IMPAD1,PLCG2,PPP4R1,PAPL,PALD1,DLG1,DUSP10,PDE4D,PIKFYVE,MINPP1,PTPRE,PLCB2,CTDSP2,SSH3,PTPRU,PTPN9,PDE5A,DUSP4,EDNRA,GPLD1,PTPRF,NUDT16,ENPP1,PLCG1,PLCH1,ATP1A1,PTPRJ,GDE1,PLPP3,PHLPP2,PPM1H,INPP4B,PLD1,CPPED1 |
| 1.171e-02 | -4.45 | microtubule-based process | biological process | GO:0007017 | 517 | 69 | 16441 | 1675 |
GAS2L1,DYNLRB1,SPC25,DLGAP5,AK7,NDC80,STIL,TTC21B,WEE1,SS18,LRRC6,KIF14,DLG1,PLK4,TUBG1,RASGRP1,DNAAF3,CHP1,PLK1,SPEF2,CAMSAP3,CENPA,KIFC2,CELSR2,CAPN6,FIGNL1,KIF1C,EZR,KIF13A,NUSAP1,DAG1,CDK1,NIN,MAP2,PLK2,TRAF3IP1,RGS14,KIF23,GPSM2,RAB6A,DNAH3,LMNA,KIF5B,LLGL2,KIF13B,TBCD,KLC3,NEK2,SPRY2,SUN2,LCA5,RHOA,KIF20A,CFAP46,TACC1,ASPM,MYBL2,STMN3,NPHP3,BBS2,KIF11,RANBP9,DCTN6,AURKA,PPP2R3C,CENPE,WDR62,NDE1,ESPL1 |
| 1.171e-02 | -4.45 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 189 | 29 | 17758 | 1761 |
SLC35D2,ARHGEF3,SORBS1,RUNX2,UBASH3B,PANK1,TMX4,RGS20,UTRN,ARFRP1,GRK6,RAB6A,SESN1,TTYH3,OTUD1,UBE2Q2,UAP1,CYP2S1,CEP78,MADD,DTX4,ZDHHC23,SORL1,PIEZO1,C10orf54,GLCCI1,C12orf75,TPCN1,CBX7 |
| 1.171e-02 | -4.45 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | 189 | 29 | 17758 | 1761 |
MAP3K3,PLA2G4A,PPIF,PMPCB,DNAJC3,CNOT8,ABCG2,KCTD12,NUSAP1,ANLN,GTF2A2,C3orf58,SIRPA,PIAS3,RCN1,AP1AR,TIMM8A,PEX2,PLCG2,ECI2,AURKA,ABCD1,PIK3CD,RELL1,PTPRE,TRAM1,CCNB2,CDKN2D,GM2A |
| 1.171e-02 | -4.45 | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | 189 | 29 | 17758 | 1761 |
HECA,TRIM8,B3GNT2,NFKBIE,CPEB4,TACC1,OSTM1,MPP1,CAST,HLA-E,RC3H2,TMX4,SPATA13,NRG2,CAMK1D,ZFAND5,ADAMTSL4,DDR1,CMTM6,FAM111A,NOV,MLPH,SLC16A6,TMEM30A,FAM13B,S100A5,CITED2,SERPINB1,RARG |
| 1.171e-02 | -4.45 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP | 189 | 29 | 17758 | 1761 |
SUN1,LZTFL1,ZNF395,ADCK3,ATP8A1,STMN3,AES,ISYNA1,ERP29,LTBP3,RASGRP2,MARCH8,CTNNBIP1,ATP1A1,ADD3,TJP3,STIM1,FAAH,KLF3,RYK,FXYD5,ARRB1,VAT1,EIF4EBP2,WWP1,CABIN1,CDK18,PHKA2,CBX7 |
| 1.171e-02 | -4.45 | GSE14308_TH2_VS_TH17_UP | MSigDB lists | GSE14308_TH2_VS_TH17_UP | 189 | 29 | 17758 | 1761 |
ENPP4,CASP3,CAMSAP3,MRPS33,TRIM8,PCOLCE,ASPM,CIT,LPGAT1,PBX3,AK4,CDCA2,STIL,ANKRD29,HMGXB4,MFSD2A,OSBPL3,SIPA1L1,FAM20B,RYK,PPM1H,FAM63A,MAPK11,SP6,CENPE,PIK3CD,ARPC2,E2F8,ESPL1 |
| 1.171e-02 | -4.45 | GSE12366_GC_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_DN | 189 | 29 | 17758 | 1761 |
LAMP1,CD55,PARP12,TSC22D3,HLA-F,ASAH1,TGOLN2,IL27RA,CAMK1D,SNN,FNDC3A,SESN1,LTBP3,DGKE,ZNF275,TMEM63A,ARHGAP24,SNX18,ANKRD6,FOSB,PGM2L1,TMBIM6,SERPINB6,OAS3,SPCS3,ZMIZ1,NDFIP1,CRTAP,SMAGP |
| 1.171e-02 | -4.45 | V$HEN1_02 | MSigDB lists | V$HEN1_02 | 189 | 29 | 17758 | 1761 |
CCNE2,DOCK4,TGIF1,ADAMTS2,CALM1,ETV5,RGAG1,CBX6,PRICKLE1,CALM3,NDUFA4,F11R,PSME1,PRKACA,PDGFB,CHPF,CALM2,IRF2BPL,PTK7,FAM13B,SLC44A1,NR4A3,SLC44A2,ADAM15,GRIN2D,NR4A2,NRG1,SULT2B1,MYT1 |
| 1.171e-02 | -4.45 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 189 | 29 | 17758 | 1761 |
GFPT1,CASP3,TIMP2,LGALS3,CALM1,C1GALT1C1,CALM3,FNDC3A,CHPF,LRRC42,RCN1,CALM2,GNS,SS18,C7orf49,SLC25A4,RBM47,DNM1L,WIPI1,IMPAD1,WFS1,BHLHE41,FUT8,RRBP1,ERAP1,AURKA,GOT1,ADIPOR1,FAM69A |
| 1.171e-02 | -4.45 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_UP | 189 | 29 | 17758 | 1761 |
ANXA3,ARMCX3,TSPAN15,ITCH,ABCG2,KIF1C,HMGN3,PSME1,SNN,GALNT3,RND3,KCNN4,IL6ST,ELF5,FXYD5,PLEKHF1,HS3ST3B1,ECE1,ARF6,PDIA6,UBE2C,TRAM1,SERPINB1,MAFF,S100A13,RARG,GM2A,MELK,MYO5A |
| 1.174e-02 | -4.45 | TBK1.DN.48HRS_UP | MSigDB lists | TBK1.DN.48HRS_UP | 52 | 11 | 17758 | 1761 |
CALM2,CALM1,ARL4C,UBE2J1,CALM3,SLC11A2,PIK3C2B,ZMIZ1,DDR1,LBR,APPBP2 |
| 1.174e-02 | -4.45 | MORF_BUB1 | MSigDB lists | MORF_BUB1 | 52 | 11 | 17758 | 1761 |
HMMR,PLK1,ZWINT,DLGAP5,FOXM1,KIF14,NDC80,BUB1,CCNB1,KIF11,ESPL1 |
| 1.175e-02 | -4.44 | post-embryonic development | biological process | GO:0009791 | 100 | 18 | 16441 | 1675 |
EMX1,RC3H2,ACO1,GABRG2,TGFBR1,PYGO1,SEPP1,SGPL1,MECOM,GNAS,FGFR2,IMPAD1,ITPR1,BAX,NR4A2,FZD5,MYT1,TIPARP |
| 1.175e-02 | -4.44 | EHD1 (EH domain containing 1) | protein interactions | 10938 | 61 | 13 | 16036 | 1726 |
PLA2G4A,EPN3,IGF1R,RAB11FIP2,DGKQ,STK39,TECR,PRKRA,NUBP1,HSPB1,VPS26A,EHD1,FAS |
| 1.175e-02 | -4.44 | OS9 (osteosarcoma amplified 9, endoplasmic reticulum lectin) | protein interactions | 10956 | 61 | 13 | 16036 | 1726 |
ERLEC1,KLK5,SERPINA1,FOXM1,PLOD2,UBE2J1,DNAJB11,SARAF,GGH,SERPINI1,FBXO6,EGLN3,EGLN1 |
| 1.178e-02 | -4.44 | GSE14000_4H_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_DN | 181 | 28 | 17758 | 1761 |
ANXA3,MRPL44,NUB1,C5orf30,RAB23,BTN3A2,BTN3A1,GGH,LRRC1,LHFPL2,LGALS3BP,BSDC1,KCTD9,EPDR1,TMCC3,SLC25A36,PIAS3,SS18,SETDB2,PHLPP2,TPST1,CSTF2,AGFG2,KLF5,MRPS28,TRAF5,C9orf72,FAM69A |
| 1.178e-02 | -4.44 | GSE14000_4H_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_UP | 181 | 28 | 17758 | 1761 |
DDX58,PLA2G4A,EPAS1,MPP1,DAP,S100A4,UBASH3B,BLVRB,PARP4,NDUFA4,FAM198B,MGST2,PDK3,ATP1B1,SLC25A5,ATP5H,DTX4,CLDN4,SLC27A1,AHCY,KLF9,SPCS3,TECR,LMAN1,LTA4H,RARG,OSGIN1,CD33 |
| 1.178e-02 | -4.44 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | 181 | 28 | 17758 | 1761 |
BIN1,AVPI1,MCTP1,GRHL2,RIPK2,GALNT12,ITGA6,MTL5,SELL,TFAP2C,EPHA1,KBTBD11,NRP2,RASGRP2,SCARB2,ACVRL1,TSPAN6,SLC16A6,PRICKLE3,IL6ST,TPST1,LTBP2,ICOSLG,TSPAN1,NCAM1,ALS2CL,TOB1,XKR8 |
| 1.180e-02 | -4.44 | Programmed Cell Death | REACTOME pathways | R-HSA-5357801 | 163 | 27 | 8202 | 867 |
CASP3,BMF,PSMB4,ADD1,AKT1,PSME2,CASP9,TP53,PSMD10,PRKCQ,PSME1,BCL2L1,PSMA4,BCAP31,LMNA,FAS,DAPK2,PSMD1,CDH1,DNM1L,H1F0,STK26,DAPK1,BAX,MLKL,UNC5B,OCLN |
| 1.180e-02 | -4.44 | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | MSigDB lists | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | 157 | 25 | 17758 | 1761 |
HMMR,ZWINT,SEC61B,CEP70,DLGAP5,KIF20A,FOXM1,PBK,NUF2,CCNB1,ADAMTSL4,CDK1,STEAP1,PARM1,CABP1,BHLHE41,KIF14,PHTF1,TUBG1,AURKA,ANO4,SHROOM2,CCNB2,E2F8,DENND5B |
| 1.182e-02 | -4.44 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | 173 | 27 | 17758 | 1761 |
TXN,MFI2,LONRF3,GNPDA1,UBASH3B,DUSP4,FNDC3A,RHEB,SCML1,M6PR,BCAR3,ZFYVE16,SLCO4A1,PRKAG2,ETS2,UAP1,CSF1,CORO1C,SGK1,RAB20,GLA,GEM,EGLN3,ESYT2,WBP5,RRAGD,CKS2 |
| 1.183e-02 | -4.44 | negative regulation of response to wounding | biological process | GO:1903035 | 153 | 25 | 16441 | 1675 |
SERPINE2,PSMB4,NLRX1,PLAUR,UBASH3B,PBK,EPHA4,PTGER4,PPARA,F12,PDGFB,ETS1,GSTP1,ABR,SOCS3,IER3,CD109,PDGFA,NOV,ADORA1,PRKG1,NOD2,DUSP10,GPER1,NDFIP1 |
| 1.183e-02 | -4.44 | regulation of cell cycle G1/S phase transition | biological process | GO:1902806 | 153 | 25 | 16441 | 1675 |
PSMB4,AKT1,PSME2,CUL4B,CTDSPL,TP53,RGCC,PSMD10,PSME1,PSMA4,SUSD2,JADE1,CCND1,E2F7,CYP1A1,PSMD1,TJP3,PTEN,DACT1,KIF14,FAM83D,CDKN1B,FHL1,PIM1,CTDSP2 |
| 1.183e-02 | -4.44 | positive regulation of epithelial cell proliferation | biological process | GO:0050679 | 153 | 25 | 16441 | 1675 |
GRN,SIRT1,SCN5A,AKT1,NR4A1,SOX9,ERBB2,TGFBR1,OSR2,PDGFB,FZD7,NRP2,CCND1,FGFR2,SCG2,ACVRL1,TBX18,NR4A3,NOD2,CDH3,EGFL7,TWIST1,MYDGF,OSR1,IQGAP3 |
| 1.184e-02 | -4.44 | PID_INTEGRIN1_PATHWAY | MSigDB lists | PID_INTEGRIN1_PATHWAY | 66 | 13 | 17758 | 1761 |
MDK,COL6A2,ITGA3,NPNT,ITGA7,PLAUR,ITGA6,COL6A1,COL18A1,COL4A5,COL7A1,IGSF8,ITGAV |
| 1.184e-02 | -4.44 | RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | RAS_PROTEIN_SIGNAL_TRANSDUCTION | 66 | 13 | 17758 | 1761 |
ARAP3,RHOA,LIMK1,RALBP1,FGD6,ARHGDIB,MRAS,PLD1,ARF6,ABCA1,RASGRP1,FGD1,FARP2 |
| 1.184e-02 | -4.44 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 66 | 13 | 17758 | 1761 |
IRS2,LTBP1,NOV,IGF1R,NR4A1,MITF,SAT1,BCL6,KLF9,ITPR2,CITED2,LEPR,PARM1 |
| 1.185e-02 | -4.44 | V$MYCMAX_B | MSigDB lists | V$MYCMAX_B | 255 | 37 | 17758 | 1761 |
EPS8,CALM3,CRABP2,PDGFB,HPCAL4,H1FX,IRF2BPL,CCND1,CALM2,TFAP4,WEE1,DAZAP1,PHF7,CDK16,ZNRF2,XYLT2,BHLHE41,TOX2,RANBP1,SUN2,TGIF1,TRIM8,CALM1,TFAP2C,SLC25A5,SOCS3,PRKAG2,SYT7,RND3,ZNF367,HOXA9,PTK7,PITPNA,HMGA1,HS3ST3B1,ARF6,RNF146 |
| 1.188e-02 | -4.43 | HDL cholesterol(PMID:21909109) | GWAS genes | HDL cholesterol(PMID:21909109) | 5 | 3 | 2389 | 269 |
OAS3,PVRL2,ABCA1 |
| 1.188e-02 | -4.43 | ZBTB7A (zinc finger and BTB domain containing 7A) | protein interactions | 51341 | 30 | 8 | 16036 | 1726 |
TFAP4,SIRT1,NFKBIA,SOX9,TP53,BCL6,HDAC1,SP4 |
| 1.188e-02 | -4.43 | IL2RG (interleukin 2 receptor, gamma) | protein interactions | 3561 | 30 | 8 | 16036 | 1726 |
PTPRJ,JAK1,IL15RA,IL15,IL13RA1,WWP1,JAK3,WWP2 |
| 1.188e-02 | -4.43 | APLP2 (amyloid beta (A4) precursor-like protein 2) | protein interactions | 334 | 30 | 8 | 16036 | 1726 |
APLP2,AKT1,RYK,PIK3CA,ADIPOR1,ETS1,CDK1,HLA-A |
| 1.190e-02 | -4.43 | MASSARWEH_RESPONSE_TO_ESTRADIOL | MSigDB lists | MASSARWEH_RESPONSE_TO_ESTRADIOL | 59 | 12 | 17758 | 1761 |
IL17RB,TOP2A,ADD3,IGF1R,PRSS23,MAP2,AMFR,SYBU,LRIG1,GLA,TIPARP,MYBL1 |
| 1.190e-02 | -4.43 | MODULE_164 | MSigDB lists | MODULE_164 | 59 | 12 | 17758 | 1761 |
ANXA3,APLP2,TIMP2,TIMP3,CDKN1C,DNAJC3,SPINT2,CST3,COL7A1,SERPINB6,SERPINB1,PKIA |
| 1.190e-02 | -4.43 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | 59 | 12 | 17758 | 1761 |
CARHSP1,MMD,ZNF395,TMX4,CD9,MORC4,ARRB1,PRKAR2B,OSTF1,EPB41L4B,NTAN1,FAM69A |
| 1.190e-02 | -4.43 | chr8q22 | MSigDB lists | chr8q22 | 59 | 12 | 17758 | 1761 |
CCNE2,CTHRC1,FAM92A1,CA2,GRHL2,ESRP1,MATN2,OSR2,INTS8,COX6C,MYBL1,FZD6 |
| 1.191e-02 | -4.43 | KIM_WT1_TARGETS_8HR_DN | MSigDB lists | KIM_WT1_TARGETS_8HR_DN | 118 | 20 | 17758 | 1761 |
CDKN1C,MTL5,RET,MTRF1L,SLC11A2,IL18,SPTLC2,STK17A,CTGF,FAM64A,PLK2,SIVA1,DACT1,CALD1,FJX1,GTF2F2,NRG1,MANF,CITED2,F2RL1 |
| 1.191e-02 | -4.43 | Ald_Xan_dh_C | smart domains | SM01008 | 2 | 2 | 9131 | 997 |
AOX1,XDH |
| 1.191e-02 | -4.43 | CO_deh_flav_C | smart domains | SM01092 | 2 | 2 | 9131 | 997 |
AOX1,XDH |
| 1.193e-02 | -4.43 | hepaticobiliary system development | biological process | GO:0061008 | 115 | 20 | 16441 | 1675 |
HES1,FOXM1,THRA,CAST,RPS6KA1,SOX9,AK4,ERBB2,ICMT,NPHP3,CCND1,E2F7,ONECUT1,CYP1A1,PIK3CA,ARF6,CITED2,E2F8,COBL,JARID2 |
| 1.194e-02 | -4.43 | BIRC5 (baculoviral IAP repeat containing 5) | protein interactions | 332 | 42 | 10 | 16036 | 1726 |
CASP3,CASP9,CDCA8,AURKA,HDAC6,F2RL1,USF2,AIP,CDK1,RASA1 |
| 1.194e-02 | -4.43 | EPHB2 (EPH receptor B2) | protein interactions | 2048 | 42 | 10 | 16036 | 1726 |
HMMR,PLCG1,STK26,GRIN1,RYK,EFNA5,YES1,FOS,EFNB1,RASA1 |
| 1.195e-02 | -4.43 | inorganic ion homeostasis | biological process | GO:0098771 | 552 | 73 | 16441 | 1675 |
CCDC109B,EPAS1,ATP2C2,HEXB,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,SLC9A7,ATP6V0B,APLP2,SCNN1A,PLCG2,STEAP2,TRPC1,CNNM4,RAB20,TMEM64,SLC39A10,F2R,CHP1,CLCN3,CD55,ACO1,SLC11A2,ATP1B1,RAB38,CD40,ITPR3,EDNRA,ATP13A2,ENPP1,ATP1A1,WFS1,SLC9A6,ATP7B,INPP4B,F2RL1,MTL5,CALB2,SLC25A27,ABCG2,SLC9A2,NEO1,CA2,GATA2,BAX,SGK3,SGK1,TMBIM6,SLC12A2,ATP2B1,SLC37A1,MFI2,ERO1A,GRIN1,TTC7A,EIF2AK1,NUBP1,SFXN5,STEAP1,FECH,SWAP70,SLC4A4,ITPR1,SLC4A3,ATP1B3,MCUR1,GPER1,JAK3,NDFIP1,CYBRD1 |
| 1.199e-02 | -4.42 | UDP-galactosyltransferase activity | molecular function | GO:0035250 | 20 | 6 | 16491 | 1673 |
B3GALT6,B3GALNT1,UGT8,B4GALT4,PLOD3,A4GALT |
| 1.209e-02 | -4.42 | meninges-meningioma-transitional | COSMIC cancer mutations | meninges-meningioma-transitional | 15 | 5 | 17775 | 1757 |
CDKN2C,NF2,AKT1,PTEN,PIK3CA |
| 1.209e-02 | -4.42 | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | 15 | 5 | 17775 | 1757 |
PLCG1,AKT1,IDH1,PTEN,PIK3CA |
| 1.209e-02 | -4.42 | rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | rosette-forming_glioneuronal_tumour | 15 | 5 | 17775 | 1757 |
GNAS,AKT1,IDH1,RET,PIK3CA |
| 1.209e-02 | -4.42 | meninges-meningioma-fibroblastic | COSMIC cancer mutations | meninges-meningioma-fibroblastic | 15 | 5 | 17775 | 1757 |
CDKN2C,NF2,AKT1,PTEN,PIK3CA |
| 1.209e-02 | -4.42 | skin-groin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-groin-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-foot-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-foot-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | GH | COSMIC cancer mutations | GH | 15 | 5 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,RET,PIK3CA |
| 1.209e-02 | -4.42 | monophasic | COSMIC cancer mutations | monophasic | 15 | 5 | 17775 | 1757 |
SS18,CDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-hand-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-hand-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | transitional | COSMIC cancer mutations | transitional | 15 | 5 | 17775 | 1757 |
CDKN2C,NF2,AKT1,PTEN,PIK3CA |
| 1.209e-02 | -4.42 | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | 15 | 5 | 17775 | 1757 |
GNAS,AKT1,IDH1,RET,PIK3CA |
| 1.209e-02 | -4.42 | haemangioendothelioma | COSMIC cancer mutations | haemangioendothelioma | 15 | 5 | 17775 | 1757 |
PLCG1,AKT1,IDH1,PTEN,PIK3CA |
| 1.209e-02 | -4.42 | thymus-thymic_carcinoma | COSMIC cancer mutations | thymus-thymic_carcinoma | 15 | 5 | 17775 | 1757 |
ERBB2,AKT1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | 15 | 5 | 17775 | 1757 |
SS18,CDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | 15 | 5 | 17775 | 1757 |
SS18,CDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-chest-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-chest-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-ear-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-ear-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | pituitary-adenoma-GH | COSMIC cancer mutations | pituitary-adenoma-GH | 15 | 5 | 17775 | 1757 |
GNAS,CDKN2C,CDH1,RET,PIK3CA |
| 1.209e-02 | -4.42 | skin-adnexal_tumour-adenoid_cystic_carcinoma | COSMIC cancer mutations | skin-adnexal_tumour-adenoid_cystic_carcinoma | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | 15 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.209e-02 | -4.42 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | ko00534 | 24 | 7 | 6908 | 758 |
B3GALT6,HS6ST1,HS3ST3B1,NDST3,XYLT2,XYLT1,GLCE |
| 1.209e-02 | -4.42 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | hsa00534 | 24 | 7 | 6908 | 758 |
B3GALT6,HS6ST1,HS3ST3B1,NDST3,XYLT2,XYLT1,GLCE |
| 1.212e-02 | -4.41 | L1CAM interactions | REACTOME pathways | R-HSA-373760 | 97 | 18 | 8202 | 867 |
SCN5A,RPS6KA1,EZR,ALCAM,SPTB,RANBP9,NRP2,CNTNAP1,RPS6KA2,DPYSL2,DLG1,SPTBN5,ITGAV,DLG3,NCAM1,SCN2A,L1CAM,SCN3A |
| 1.212e-02 | -4.41 | FES (FES proto-oncogene, tyrosine kinase) | protein interactions | 2242 | 36 | 9 | 16036 | 1726 |
IRS2,DPYSL5,JAK1,PIK3R1,PLXNA1,BCAR1,JAK3,RASA1,MDFI |
| 1.215e-02 | -4.41 | PITPNA (phosphatidylinositol transfer protein, alpha) | protein interactions | 5306 | 19 | 6 | 16036 | 1726 |
PLCG1,GOT1,MLKL,MORF4L2,HSPB1,NEO1 |
| 1.215e-02 | -4.41 | ANK3 (ankyrin 3, node of Ranvier (ankyrin G)) | protein interactions | 288 | 19 | 6 | 16036 | 1726 |
SCN2A,HOOK1,TIAM1,DOK4,PIK3R1,FAS |
| 1.215e-02 | -4.41 | UBD (ubiquitin D) | protein interactions | 10537 | 19 | 6 | 16036 | 1726 |
TGFBR1,PSMB4,LRRFIP2,HDAC6,NUB1,TP53 |
| 1.215e-02 | -4.41 | VAV3 (vav 3 guanine nucleotide exchange factor) | protein interactions | 10451 | 19 | 6 | 16036 | 1726 |
ERBB2,PLCG1,ERBB3,RHOA,IGF1R,PIK3R1 |
| 1.216e-02 | -4.41 | LEE_AGING_NEOCORTEX_UP | MSigDB lists | LEE_AGING_NEOCORTEX_UP | 88 | 16 | 17758 | 1761 |
MYL9,PPP1R2,NR4A1,NUB1,SAT1,CYB561,CTSZ,CD40,FOS,LGALS3BP,M6PR,ADRBK1,LIMK1,CD9,DLG1,ATP1B3 |
| 1.216e-02 | -4.41 | V$LXR_DR4_Q3 | MSigDB lists | V$LXR_DR4_Q3 | 88 | 16 | 17758 | 1761 |
SLC2A4,PODXL2,NUAK1,BLVRB,RGAG1,TP53INP2,HPCAL4,FOXP2,PTK7,MITF,SGK1,ETV4,ABCA1,COL16A1,ABCG1,JARID2 |
| 1.216e-02 | -4.41 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 88 | 16 | 17758 | 1761 |
PGM1,ENO2,ZNF395,NR3C1,S100A4,AK4,LOXL2,PDGFB,FOS,CYP1A1,P4HA2,CITED2,EGLN3,MAFF,RRAGD,EGLN1 |
| 1.218e-02 | -4.41 | phosphatase binding | molecular function | GO:0019902 | 154 | 25 | 16491 | 1673 |
TPRN,SPRED1,AKT1,IQGAP1,PIK3R1,TP53,PPARA,ERBB2,SH2D4A,SYTL2,IRS2,CARHSP1,JAK1,CTSC,KCNN4,DLG1,NEK2,CDKN1B,CABIN1,CRY2,DAB2IP,MAP3K5,DLG3,JAK3,PPP6R1 |
| 1.222e-02 | -4.40 | MEMBRANE_PART | MSigDB lists | MEMBRANE_PART | 1607 | 186 | 17758 | 1761 |
LAMP1,BCAM,SLC25A13,EPHA4,SYTL4,CACNB4,SLC20A1,SDC1,SLC9A7,GRM5,ABCD4,HTR1D,STIM1,IL6ST,SLC44A1,DLG1,STEAP2,FUT1,ABCA2,TRPC1,CLDN4,TACSTD2,TRAM1,LAMP2,SGCE,CD55,MCTP1,ACVR1C,SNTB2,EZR,ROR1,SLC25A5,EDNRA,ENPP1,HS6ST1,KCNMB4,SLC25A4,KCNK1,GDE1,DOLPP1,ATP7B,MADD,F2RL1,CD99,FXYD3,ABCG2,B4GALT4,MERTK,TSPAN7,DOPEY2,ITGA3,LYPD3,KCNN4,SLC16A6,OPN3,FXYD5,SORL1,CD70,CACNA1D,PIKFYVE,NCAM1,SLC12A2,CKAP4,KDELR1,ABCC1,FADS2,PODXL2,PCDH1,MMD,MFI2,RGMB,EPHA1,STEAP1,STX3,GNAS,PTPRF,MMP15,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,ATP1B3,SHROOM2,SLC2A4,SORBS1,IL15,ST14,CD82,PKP2,IL27RA,IL13RA1,SLC7A2,AIFM2,EMP2,DDR1,APC2,BCAP31,SYTL2,ATP6V0B,MUC16,CDH1,VAT1,RPN2,NOTCH3,EPHB4,ECE1,LMAN1,TSPAN1,F2R,CLCN3,COG2,PTPRU,FZD4,PTGER4,IGSF8,SLC11A2,ERBB2IP,ATP1B1,CD40,DAG1,FZD7,TAPBP,ATP1A1,PTPRJ,DDOST,SHROOM3,PTK7,WFS1,AXL,MMP17,SLC9A6,PEX2,SECTM1,EFNA5,HS3ST3B1,LIFR,ABCA1,GOLIM4,CD63,TSPAN15,GABRG2,SELL,CYB561,TGFBR1,SBF1,LBR,EFNB1,SLC9A2,FZD6,M6PR,NEO1,IL17RB,ADORA1,ITGB8,BAX,SLC44A2,ATP8B1,TMBIM6,TSPAN13,ERBB3,SGCB,SYK,SLC16A5,ATP2B1,GCNT1,SYPL1,MPP1,AMFR,PLAUR,GRIN1,AIF1L,SNTB1,BCAR1,CD83,CNTNAP1,GALNT3,ACVRL1,SPINT2,PGRMC1,RYK,ABCB1,ARRB1,FZD5,GOLGB1,CD33 |
| 1.223e-02 | -4.40 | microvillus organization | biological process | GO:0032528 | 20 | 6 | 16441 | 1675 |
FXYD5,EZR,KLF5,STK26,RAPGEF2,RAP2C |
| 1.223e-02 | -4.40 | glycogen catabolic process | biological process | GO:0005980 | 20 | 6 | 16441 | 1675 |
CALM3,CALM2,GAA,PGM1,PHKA2,CALM1 |
| 1.225e-02 | -4.40 | Glyco_hydro_13_b | interpro domains | IPR013780 | 15 | 5 | 18293 | 1814 |
MAN2A2,FUCA1,MAN2B2,GLA,NAGA |
| 1.225e-02 | -4.40 | OTU_dom | interpro domains | IPR003323 | 15 | 5 | 18293 | 1814 |
OTUB2,YOD1,OTUD1,ZRANB1,ALG13 |
| 1.225e-02 | -4.40 | REGULATION_OF_MEMBRANE_POTENTIAL | MSigDB lists | REGULATION_OF_MEMBRANE_POTENTIAL | 15 | 5 | 17758 | 1761 |
BCL2L1,KCNMB4,AIFM3,IFI6,BAX |
| 1.225e-02 | -4.40 | chr2q22 | MSigDB lists | chr2q22 | 15 | 5 | 17758 | 1761 |
NR4A2,SCN2A,CACNB4,NEB,ARHGEF4 |
| 1.225e-02 | -4.40 | PID_ARF6_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ARF6_DOWNSTREAM_PATHWAY | 15 | 5 | 17758 | 1761 |
RHOA,PLD1,ARF6,TIAM1,PLAUR |
| 1.225e-02 | -4.40 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | MSigDB lists | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | 15 | 5 | 17758 | 1761 |
CALM2,CALM3,GRIN2D,CALM1,GRIN1 |
| 1.225e-02 | -4.40 | ZHAN_LATE_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_LATE_DIFFERENTIATION_GENES_DN | 15 | 5 | 17758 | 1761 |
SORL1,MYBL1,SYK,CKS2,BCL6 |
| 1.225e-02 | -4.40 | BIOCARTA_HSP27_PATHWAY | MSigDB lists | BIOCARTA_HSP27_PATHWAY | 15 | 5 | 17758 | 1761 |
MAPKAPK2,CASP3,HSPB1,CASP9,FAS |
| 1.226e-02 | -4.40 | clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_papillary_renal_cell_carcinoma | 10 | 4 | 17775 | 1757 |
IDH1,PTEN,PIK3CA,TP53 |
| 1.226e-02 | -4.40 | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | 10 | 4 | 17775 | 1757 |
CDKN2C,IDH1,PTEN,TP53 |
| 1.226e-02 | -4.40 | lung-carcinoma-micropapillary_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-micropapillary_adenocarcinoma | 10 | 4 | 17775 | 1757 |
KIF5B,ERBB2,SDC4,PIK3CA |
| 1.226e-02 | -4.40 | lung-carcinoma-pleomorphic_carcinoma | COSMIC cancer mutations | lung-carcinoma-pleomorphic_carcinoma | 10 | 4 | 17775 | 1757 |
KIF5B,ERBB2,PIK3CA,TP53 |
| 1.226e-02 | -4.40 | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | 10 | 4 | 17775 | 1757 |
IDH1,PTEN,PIK3CA,TP53 |
| 1.226e-02 | -4.40 | micropapillary_adenocarcinoma | COSMIC cancer mutations | micropapillary_adenocarcinoma | 10 | 4 | 17775 | 1757 |
KIF5B,ERBB2,SDC4,PIK3CA |
| 1.227e-02 | -4.40 | CUB | prosite domains | PS01180 | 50 | 11 | 11866 | 1235 |
PDGFC,PCOLCE,ST14,MEGF8,BMP1,NETO2,ATRNL1,KREMEN1,DCBLD1,NRP2,TLL2 |
| 1.228e-02 | -4.40 | fatty acid transport | biological process | GO:0015908 | 51 | 11 | 16441 | 1675 |
PLA2G4A,PRKAA2,ACACB,PRKAG2,SLC27A6,CPT2,MFSD2A,PPARA,SLC27A1,ABCD1,ACSL4 |
| 1.230e-02 | -4.40 | V$HNF3B_01 | MSigDB lists | V$HNF3B_01 | 206 | 31 | 17758 | 1761 |
CYP26B1,SSH3,RUNX2,FRMD4A,CPEB4,CHCHD7,RGAG1,NFIB,NFIX,IER3,FOXP2,TFAP4,KLF12,ARTN,CYR61,COL13A1,SLC16A6,CALD1,PELI2,LMO4,FUT8,SLC44A1,MITF,KLF3,NKD1,BUB1,CITED2,CLIP2,TOB1,RARG,SULF2 |
| 1.231e-02 | -4.40 | V$DBP_Q6 | MSigDB lists | V$DBP_Q6 | 239 | 35 | 17758 | 1761 |
LRRFIP2,IL18,MORF4L2,GPSM2,DENND2D,MNS1,ZNF385B,EPS8L2,SCML1,FOXP2,ANKS1B,CALD1,BHLHE41,KLF3,MITF,SERINC2,DAB2IP,CRY2,BTBD3,TGIF1,SMARCA2,KCNIP3,MGAT4B,ITPR3,NFIX,GPLD1,TAPBP,SERPINA1,RBM47,NR4A3,EFNA5,TOB1,RARG,KLF7,JARID2 |
| 1.232e-02 | -4.40 | myosin binding | molecular function | GO:0017022 | 58 | 12 | 16491 | 1673 |
MYL9,RHOA,RAB3B,CALD1,ARFGEF1,TRIOBP,SPTBN5,VEZT,RAB6A,IQGAP3,RAB27B,MYL12B |
| 1.233e-02 | -4.40 | MITOCARRIER | prints domains | PR00926 | 27 | 7 | 4759 | 462 |
SLC25A48,SLC25A24,SLC25A4,SLC25A43,SLC25A5,SLC25A13,SLC25A36 |
| 1.234e-02 | -4.40 | spindle localization | biological process | GO:0051653 | 38 | 9 | 16441 | 1675 |
CENPA,LLGL2,ASPM,NDC80,NUSAP1,GPSM2,NDE1,SPRY2,ESPL1 |
| 1.234e-02 | -4.40 | neuromuscular junction development | biological process | GO:0007528 | 38 | 9 | 16441 | 1675 |
SNTA1,FGFR2,ETV5,LRP4,CACNA2D2,ERBB2,COL4A5,CACNB4,F2R |
| 1.234e-02 | -4.40 | substrate adhesion-dependent cell spreading | biological process | GO:0034446 | 38 | 9 | 16441 | 1675 |
BVES,FZD4,KIF14,AXL,ITGAV,EPHA1,MERTK,ANTXR1,FZD7 |
| 1.234e-02 | -4.40 | cytoplasmic sequestering of protein | biological process | GO:0051220 | 38 | 9 | 16441 | 1675 |
PINK1,NFKBIE,AKT1,THRA,NFKBIA,PSMD10,PDIA3,KDELR1,MDFI |
| 1.234e-02 | -4.39 | coated vesicle | cellular component | GO:0030135 | 229 | 34 | 17570 | 1756 |
SORT1,SLC2A4,HLA-E,HLA-F,CTSZ,TGOLN2,BCAP31,HLA-A,AP1M2,CTSC,SNX18,STEAP2,CD9,ECE1,HLA-C,LMAN1,RAB27B,PACSIN1,GAD1,DVL2,KDELR1,SEC23A,FZD4,FURIN,COL7A1,MCFD2,C3orf58,EPN3,HLA-B,SERPINA1,WIPI1,SH3BP4,FZD5,NRGN |
| 1.235e-02 | -4.39 | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 677 | 85 | 17775 | 1757 |
ILDR1,FOXM1,RALBP1,RET,NDC80,TP53,COL18A1,GRK6,AIFM2,DENND2D,TNFSF9,EPS8L2,SYTL2,APLP2,TRANK1,STIM1,ZFP36,PRICKLE3,PIK3CA,FUT1,CNNM4,TMEM64,EGLN3,NEB,DVL2,CLCN3,FIGNL1,TNS1,SAV1,COL12A1,PLCH1,PTPRJ,DDOST,ANKRD6,WIPI1,ATP7B,PLEKHG1,PRKCDBP,ARRDC1,SPTBN5,ZMAT1,SCN5A,PPP1R2,LRRFIP2,FAM169A,ALPP,LLGL2,FRAS1,BMP7,MEGF8,KIF13B,BDH1,RRBP1,MAP3K9,PRKG1,FAM102A,FAR2,ZMYM1,TPCN1,CCDC88A,GPR161,MYO5A,PARP9,EPB41L5,SUN2,MFI2,NR4A1,PPARA,GYLTL1B,YES1,RNPEP,NFIB,MUM1L1,NR1D2,ACVRL1,ITPR1,NLRC5,RHOBTB2,ZDBF2,FHL1,PLOD3,WDR62,ESPL1,EHD1,SNPH |
| 1.236e-02 | -4.39 | cell cycle process | biological process | GO:0022402 | 1057 | 130 | 16441 | 1675 |
SUN1,NDC80,PSME1,CCNB1,VASH1,BARD1,CENPN,FANCI,CDKN2C,WEE1,PSMD1,CNTRL,CEP78,DLG1,TUBG1,PLK1,CENPA,PBK,EZR,PRKAR2B,KIF13A,CCNF,ANLN,SESN1,CDK1,RHEB,OPTN,PRIM1,PLK2,CAB39,KLF11,RRAGD,PRKAA2,CDKN1C,KIF23,GPSM2,LMNA,SNX18,NEK2,NUP85,CYP26B1,REC8,KIF20A,MYBL2,STRADB,PSMA4,RASA1,MAPKAPK2,PRKAG2,FAM64A,CGREF1,CDCA5,FAM83D,AURKA,NDE1,CCNB2,NUP58,GAS2L1,CCNE2,DLGAP5,CEP70,SPC25,FOXM1,ACTR8,PSME2,PTTG1,TP53,NUF2,TDRKH,BCL2L1,STIL,PRKACA,IER3,CCND1,SETDB2,KIF14,PLK4,CDKN1B,CDKN2D,CKS2,SEPT6,CDC20,CDCA2,NUSAP1,PKMYT1,RAD17,TRIOBP,OVOL1,RGS14,REEP4,PPP2R2D,MAPK12,NKX3-1,CKAP2,KLHL13,ARHGEF11,CIT,EPS8,CDCA8,PSMD10,TGFBR1,FBXO6,TIPRL,SAC3D1,TOP2A,E2F7,PTEN,LLGL2,BUB1,IQGAP3,SPRY2,SUN2,ZWINT,RHOA,PSMB4,ASPM,RGCC,DIAPH2,BORA,KIF11,DCTN6,ABCB1,CENPE,GEM,WDR62,CEP41,UBE2C,NCAPG2,ESPL1,MELK |
| 1.237e-02 | -4.39 | innate immune response-activating signal transduction | biological process | GO:0002758 | 241 | 36 | 16441 | 1675 |
DDX58,RPS6KA1,PSME2,CALM3,PSMD10,PSME1,ITPR2,PRKACA,CALM2,RPS6KA2,PSMD1,PIK3AP1,PLCG2,MAPK11,SCARA3,LGMN,CNPY3,SYK,TNIP1,PSMB4,RIPK2,ITCH,CALM1,ITPR3,ELK1,DUSP4,FOS,PSMA4,MAPKAPK2,CTSL,PELI2,ITPR1,NFKBIA,NOD2,IRF7,IFIH1 |
| 1.240e-02 | -4.39 | PTB/PI_dom | interpro domains | IPR006020 | 39 | 9 | 18293 | 1814 |
TNS3,TBC1D1,SHC3,ANKS1B,EPS8,TNS1,TBC1D4,MAPK8IP1,EPS8L2 |
| 1.240e-02 | -4.39 | Diacylglycerol_kin_accessory | interpro domains | IPR000756 | 10 | 4 | 18293 | 1814 |
DGKH,DGKG,DGKE,DGKQ |
| 1.240e-02 | -4.39 | Anoctamin | interpro domains | IPR007632 | 10 | 4 | 18293 | 1814 |
ANO9,ANO4,ANO1,ANO6 |
| 1.240e-02 | -4.39 | Pept_asp_AS | interpro domains | IPR025661 | 10 | 4 | 18293 | 1814 |
CTSL,CTSZ,CTSC,CTSV |
| 1.240e-02 | -4.39 | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | 10 | 4 | 17758 | 1761 |
KLF11,PLCG1,CELSR2,ELK1 |
| 1.240e-02 | -4.39 | MAP_KINASE_KINASE_KINASE_ACTIVITY | MSigDB lists | MAP_KINASE_KINASE_KINASE_ACTIVITY | 10 | 4 | 17758 | 1761 |
MAP3K3,MAP3K5,MAP3K6,MAP3K9 |
| 1.240e-02 | -4.39 | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | MSigDB lists | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | 10 | 4 | 17758 | 1761 |
MAPKAPK2,PRKAG2,PACSIN2,PIM1 |
| 1.240e-02 | -4.39 | TURJANSKI_MAPK14_TARGETS | MSigDB lists | TURJANSKI_MAPK14_TARGETS | 10 | 4 | 17758 | 1761 |
ELK1,FOS,STAT4,TP53 |
| 1.240e-02 | -4.39 | OXIDOREDUCTASE_ACTIVITY_GO_0016706 | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_GO_0016706 | 10 | 4 | 17758 | 1761 |
PLOD3,PLOD2,P4HA2,EGLN1 |
| 1.240e-02 | -4.39 | ANTIPORTER_ACTIVITY | MSigDB lists | ANTIPORTER_ACTIVITY | 10 | 4 | 17758 | 1761 |
SLC9A6,SLC9A2,SLC9A7,SLC4A3 |
| 1.240e-02 | -4.39 | KEGG_LIMONENE_AND_PINENE_DEGRADATION | MSigDB lists | KEGG_LIMONENE_AND_PINENE_DEGRADATION | 10 | 4 | 17758 | 1761 |
YOD1,ALDH7A1,ALDH2,ALDH3A2 |
| 1.240e-02 | -4.39 | CHROMOSOME_CONDENSATION | MSigDB lists | CHROMOSOME_CONDENSATION | 10 | 4 | 17758 | 1761 |
TOP2A,NUSAP1,AIFM2,CDCA5 |
| 1.240e-02 | -4.39 | LYSOSOMAL_MEMBRANE | MSigDB lists | LYSOSOMAL_MEMBRANE | 10 | 4 | 17758 | 1761 |
LAMP2,CD63,LAMP3,ABCA2 |
| 1.240e-02 | -4.39 | REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | REGULATION_OF_CELL_CELL_ADHESION | 10 | 4 | 17758 | 1761 |
NF2,PTEN,ACVRL1,RASA1 |
| 1.243e-02 | -4.39 | CRX_NRL_DN.V1_UP | MSigDB lists | CRX_NRL_DN.V1_UP | 134 | 22 | 17758 | 1761 |
REC8,PCOLCE,SNTB2,PIP4K2C,PPARA,PDIA5,GPSM2,CAMK1D,GRTP1,DHRS3,STK17B,IER3,SNTA1,CDKN2C,AHRR,LLGL2,ZDHHC12,KCNN4,SLC16A6,ARL4D,FAIM,ST3GAL1 |
| 1.243e-02 | -4.39 | WWTAAGGC_UNKNOWN | MSigDB lists | WWTAAGGC_UNKNOWN | 134 | 22 | 17758 | 1761 |
MYL9,SMARCA2,SLC2A4,SORBS1,ETV5,TFAP2C,GRK6,PPP1R14C,SDC1,GSTP1,NFIB,FGF19,HDAC9,ANKRD10,SESN3,WIPI1,MAP2,SLC16A6,PDE4D,ARF6,NCAM1,RBMS2 |
| 1.244e-02 | -4.39 | HALLMARK_APICAL_JUNCTION | MSigDB lists | HALLMARK_APICAL_JUNCTION | 198 | 30 | 17758 | 1761 |
MYL9,CD99,PVRL4,SGCE,PCDH1,NF2,CRB3,CALB2,MPP5,CD274,RASA1,SIRPA,MDK,PLCG1,ITGA3,CDH1,PTEN,PVRL2,DLG1,BMP1,ADAM15,TUBG1,CDH3,CLDN4,MAPK11,ARPC2,SHROOM2,COL16A1,SYK,MYL12B |
| 1.244e-02 | -4.39 | GSE17721_LPS_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_6H_BMDM_UP | 198 | 30 | 17758 | 1761 |
PMPCB,CAPN6,FURIN,HMGN3,NCKAP1,TNFSF9,RASA1,STX3,RCN1,CA2,FUT2,RBL1,PHTF1,RANBP1,RAP2C,FAM110C,CDKN1B,TRIM21,STK39,SH3BGRL2,SP6,ITGAV,SERPINB1,SNX10,IFIH1,NRBP1,CPPED1,HOXC13,RBMS2,USP43 |
| 1.244e-02 | -4.39 | MODULE_205 | MSigDB lists | MODULE_205 | 281 | 40 | 17758 | 1761 |
KIAA1462,ZNF395,DLGAP5,HJURP,ST14,FLYWCH2,ITGA6,ARMC7,CACNA2D2,TP53,INTS8,GPSM2,B4GALT4,DNER,TMPRSS4,CD109,MDM1,MUC16,KIF14,NEK2,ABCA2,DIXDC1,EGLN3,MYRIP,ULBP2,ATG4D,DPYSL5,HPS3,CITED4,XRCC6BP1,CACHD1,TWSG1,FAM114A1,SERPINI1,TANC2,TMEM159,CEP41,TRAF5,E2F8,RRAGD |
| 1.246e-02 | -4.39 | lipid transporter activity | molecular function | GO:0005319 | 101 | 18 | 16491 | 1673 |
PLSCR1,ATP9A,ATP8A1,ANO6,ATP8B3,ANO9,PCTP,CPTP,ATP10D,MFSD2A,ATP8B1,SLC27A1,PITPNA,ABCD1,ANO4,ABCA1,GM2A,ABCG1 |
| 1.246e-02 | -4.39 | intracellular receptor signaling pathway | biological process | GO:0030522 | 185 | 29 | 16441 | 1675 |
DDX58,THRB,NKX3-1,TXN,RHOA,RIPK2,NR3C1,NR4A1,THRA,ITCH,PPARA,BCL2L1,PDK3,NCOA3,SP100,NR1D2,NFKBIA,NOD2,NR4A3,CRY2,IRF7,NR4A2,GPER1,PIM1,IFIH1,RARG,MED30,AHR,NCOA2 |
| 1.246e-02 | -4.39 | membrane lipid metabolic process | biological process | GO:0006643 | 185 | 29 | 16441 | 1675 |
UGT8,PLAUR,HEXB,ASAH1,TEX2,B4GALT4,ARSK,SPTLC2,CPTP,SGPL1,GPLD1,B4GALNT1,ALDH3B1,ALDH5A1,ITGB8,ARSG,A4GALT,PLPP3,SERINC2,BAX,CTSA,PLD1,GLA,ARSB,ST3GAL1,NAGA,ALDH3A2,GM2A,CYP1B1 |
| 1.248e-02 | -4.38 | regulation of coagulation | biological process | GO:0050818 | 86 | 16 | 16441 | 1675 |
ENPP4,SERPINE2,PLAUR,UBASH3B,ANO6,PRKCQ,TEC,F12,PDGFB,PDGFA,HPSE,FAM46A,PRKG1,F2RL1,F2R,SYK |
| 1.248e-02 | -4.38 | bone morphogenesis | biological process | GO:0060349 | 86 | 16 | 16441 | 1675 |
CYP26B1,RUNX2,HSPG2,SOX9,RAB23,OSR2,DHRS3,GNAS,COL13A1,FGFR2,MEGF8,IMPAD1,TFAP2A,TWIST1,RARG,SP5 |
| 1.250e-02 | -4.38 | DARS2 (aspartyl-tRNA synthetase 2, mitochondrial) | protein interactions | 55157 | 14 | 5 | 16036 | 1726 |
DPYSL5,POR,PLAUR,ARHGEF26,DCP2 |
| 1.250e-02 | -4.38 | FBN2 (fibrillin 2) | protein interactions | 2201 | 14 | 5 | 16036 | 1726 |
AURKA,LTBP1,FBXO6,PTEN,MATN2 |
| 1.250e-02 | -4.38 | COLEC10 (collectin sub-family member 10 (C-type lectin)) | protein interactions | 10584 | 14 | 5 | 16036 | 1726 |
TIMP3,NUCB2,CKAP4,DCP2,DNAJB9 |
| 1.250e-02 | -4.38 | HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1) | protein interactions | 3290 | 14 | 5 | 16036 | 1726 |
TMBIM6,GLB1L2,UGT8,TMX4,FAM69A |
| 1.250e-02 | -4.38 | BMP1 (bone morphogenetic protein 1) | protein interactions | 649 | 14 | 5 | 16036 | 1726 |
COL7A1,GEM,HSPG2,TWSG1,TP53 |
| 1.250e-02 | -4.38 | SDF2L1 (stromal cell-derived factor 2-like 1) | protein interactions | 23753 | 14 | 5 | 16036 | 1726 |
VWA1,DNAJB11,SLC2A4,FBXO6,PDIA5 |
| 1.251e-02 | -4.38 | Angiogenesis | WikiPathways | WP1539 | 23 | 7 | 4455 | 516 |
PLCG1,TIMP3,TIMP2,AKT1,FGFR2,PDGFB,PIK3CA |
| 1.254e-02 | -4.38 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4310 | 465 | 17775 | 1757 |
HECA,ACACB,GAA,ADD1,SSH1,HSPG2,DNAJC3,HEXB,RET,TAP1,FBXO2,NRG2,VASH1,FAM101B,LTBP3,EPDR1,CDKN2C,CYP1A1,RGS3,CABP1,OSBPL3,PAQR5,ALDH1A3,KLF3,AOX1,KCNS3,PIK3CA,ATRNL1,CRY2,HYLS1,MTMR11,RCAN3,APOBEC3G,ERAP2,DNAAF3,NWD1,SPEF2,SMARCA2,TNIP1,SPATA18,ACVR1C,CASP9,CDA,KIF13A,LOXL2,CCNF,COL12A1,PIAS3,ENPP1,DNM1L,ANKRD6,PLK2,GNPTAB,FAM114A1,NOD2,TANC2,LZTS1,FGD1,DDX58,SCN5A,FRMD4A,TBC1D1,ITGA6,DGKQ,RAB23,KIF23,SLC1A3,MERTK,LMNA,KIAA1161,MARCH8,DOPEY2,CYR61,ZNRF2,FAM189A1,MEGF8,FLRT3,AIM1,OPN3,SORL1,CADPS2,ALPK1,PIKFYVE,ZMYM1,PPP6R1,RIMS2,IGSF3,SOCS5,GFPT1,KCNJ12,SLC37A1,MFI2,PRSS23,ADCK3,MICB,AMER1,MYBL2,ATP8B3,ANTXR1,GNA11,FRMD4B,FAS,DGKH,NCOA3,AP1AR,TJP3,FAM64A,ETS2,SEMA4D,DCK,ITPR1,FAM83D,AGBL5,CABIN1,DRP2,MAP3K5,PLIN3,PER3,IFIH1,TMEM173,XDH,ADAMTS16,EHD1,DOCK9,PLA2G4A,MTM1,SPRED1,PAPSS2,NLRX1,GALNT12,DDIT4L,PTTG1,RGS20,TESK2,PKP2,KCTD12,CYP39A1,APLP2,MUC16,FAM46A,SH3BP1,RTKN2,LGMN,PHKA2,MYT1,NR2C1,NAGA,SCN3A,ATG4D,DOCK4,MX1,CAMSAP3,SEC23A,COL6A2,RIPK2,FOXJ2,SYNE2,PRKCQ,PYGO1,ITPR3,ALCAM,ATP10D,ZNF469,NFIX,NIN,EPHA10,WFS1,CORO1C,SLC9A6,TRIOBP,PLEKHG1,FAM195A,SLC27A1,KLF5,NRG1,MLKL,COBL,CTHRC1,PCOLCE,ESRP1,CENPI,RASSF7,PBX3,CYB561,APOBEC3H,NUCB2,PLPPR4,GSTP1,ETS1,DNAH3,BEX2,NEO1,CXCL16,ADD3,ARSG,PTEN,FJX1,TMBIM6,IGFBP2,ERBB3,NPTXR,TPCN1,PARP9,AMOTL2,TGIF1,ARAP2,SHMT1,FMN1,MFSD2B,PIK3R1,FURIN,MYEOV,DIAPH2,LRRC1,GRTP1,MAMDC4,PLOD2,FGFR2,RAB11FIP2,ACVRL1,DBI,ABCB1,PPM1H,ERAP1,CENPE,FHL1,FZD5,NCAPG2,DEF6,OCLN,TMEM131,RGMA,JARID2,LTBP1,NMRK1,BCAM,KIAA1462,CAMKK1,CPT2,FHDC1,NENF,DNER,TMC1,SPTB,SH3KBP1,PTCHD4,SUSD2,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,TSPAN6,PHTF1,ANKFN1,DLG1,TMEM143,ABCA2,MYH14,ANO4,TECR,SLC39A10,TLN2,NEB,CCDC38,CYP1B1,ZNF462,THRB,MCTP1,CD55,RGAG1,EZR,CR2,IDH1,KDM4D,OPTN,HS6ST1,PLCH1,NEIL1,HPSE,MAP2,P4HA2,ZNF367,MADD,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,RAP1GAP,CAPN1,PRSS8,GRN,FAM213B,ARAP3,LGALS3,PEX6,RASA2,PYROXD2,ABCG2,PDCL,HES2,CNTNAP2,PHLPP1,ADAMTSL4,FBLN1,ANO1,UBE2Q2,IGF1R,FRAS1,KCNN4,TBCD,COL6A1,FXYD5,ZRANB1,PLCB2,CCDC88A,DPYSL5,PODXL2,SPATA13,GYLTL1B,VWA1,BTN3A2,TCF7,RANBP9,MUM1L1,RASGRP2,GNAS,FECH,COL13A1,H1F0,ITGA7,NLRC5,RHOBTB2,YOD1,DONSON,LTBP2,PLD1,ZDBF2,SHROOM2,USP43,CCNE2,NCKAP5,SORBS1,UPF3B,TP53,MORC4,COL18A1,ERBB2,SLC7A2,ARHGEF16,SYTL2,CYP26A1,IER3,PDGFA,SS18,ZNF687,ARTN,WDR44,PLCG2,BCL6,ESPN,NOTCH3,OAS3,ECE1,MINPP1,SCN2A,PPIF,AKT1,SLC39A8,OSTM1,ACO1,PTGER4,DUSP4,DOCK5,ATP13A2,ARHGAP35,DUOX1,PTPRJ,ALDH5A1,BFSP1,ABHD12,PTK7,STK38,ADAMTS14,SPTBN5,IRF7,ANXA9,ST3GAL1,REEP4,ABCA1,GLIS3,COL9A3,TM2D2,CDH22,KLHL13,ARHGEF11,MACC1,RUSC2,LRP4,COL4A5,GDF15,NOTUM,SBF1,DSE,CRABP2,LBR,SH2D4A,FZD6,TMEM63A,HDAC9,CD109,KIF5B,IL17RB,IRF2BPL,CARD8,ADORA1,MLPH,LLGL2,TOX2,TFAP2A,FAM63A,KIAA0319,TSPAN13,BUB1,IQGAP3,C12orf75,MYO5A,GCNT1,IGDCC4,NFE2L3,HMMR,SUN2,MOSPD2,NR4A1,PLAUR,ASPM,SYBU,LITAF,PPARA,LRRC66,TTC7A,PRICKLE1,MAML2,COL7A1,RNPEP,BCAR1,TXNDC11,BBS2,LEPR,HLA-B,SERPINA1,FAT4,TWSG1,NAT1,NETO2,PPP2R3C,PLOD3,ICOSLG,SOX8,TBC1D4,PTGES,AHR,ARHGEF4,GOLGB1 |
| 1.255e-02 | -4.38 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | 190 | 29 | 17758 | 1761 |
PAPSS2,PQLC3,GNPDA1,AMFR,STAT4,ITCH,LPGAT1,TSC22D3,INPP5D,SPATA13,UTRN,MRAS,SLC7A2,ATP1B1,MCFD2,TXNDC11,ADD3,UAP1,REEP1,OPN3,SNX16,DONSON,ERBB3,LRRK1,RCAN3,CEP41,MYLIP,MAFF,PAQR7 |
| 1.255e-02 | -4.38 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | 190 | 29 | 17758 | 1761 |
CD99,HOXB7,GNPDA1,ITGA6,PLEKHO1,PTTG1,NUSAP1,SESN1,TSEN34,NFIX,NCOA3,WEE1,DAZAP1,COQ10A,H1F0,SH3BP1,METTL7A,DOLPP1,LMO4,AIM1,PCYOX1,ARRB1,ABCD1,PHKA2,RCAN3,RNF26,S100A6,MELK,PAQR7 |
| 1.255e-02 | -4.38 | GSE22886_TH1_VS_TH2_48H_ACT_UP | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_UP | 190 | 29 | 17758 | 1761 |
SORBS1,LGALS3,RIPK2,ST14,GABRG2,MRAS,CRISPLD2,FZD7,CD83,IER3,B3GALNT1,BFSP1,KCNN4,FLRT3,PLCG2,PPP4R1,FJX1,SIPA1L1,PRKCDBP,SGK1,TNFRSF12A,LTBP2,ECE1,RAP1GAP,SMYD5,HSPB1,FAH,C9orf9,TLL2 |
| 1.255e-02 | -4.38 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | 190 | 29 | 17758 | 1761 |
HECA,GOLIM4,TNRC6C,SORBS1,CAMKK1,ARL4C,SERTAD3,TCF7,YES1,DOCK5,SEPP1,SLC20A1,HLA-A,NRP2,IER3,AMZ2,PLCG1,JAK1,FRY,NR1D2,STK38,PGM2L1,CDKN1B,SGK1,C10orf54,PIK3CD,MYLIP,RASGRP1,SULF2 |
| 1.257e-02 | -4.38 | V$CREB_Q2 | MSigDB lists | V$CREB_Q2 | 256 | 37 | 17758 | 1761 |
LTBP1,TM2D2,MRC2,TSC22D3,DNAJB2,LMCD1,RAB6A,FAM167A,TSPAN7,CHPF,IRF2BPL,AKIRIN1,CXCL16,ZNF687,DACT1,FOSB,PLK4,RFX5,TAGLN2,ARL4D,RBMS2,WBP5,CLCN3,PTPRU,NR3C1,FOS,TP53INP2,GNAS,PITX2,SCG2,ZNF367,NR4A3,NR4A2,GEM,OSR1,MAFF,RUSC1 |
| 1.257e-02 | -4.38 | SH3DOMAIN | prints domains | PR00452 | 83 | 15 | 4759 | 462 |
BIN1,LASP1,PLCG1,PACSIN2,SORBS1,PLCG2,MAP3K9,OSTF1,YES1,TEC,CTTN,PACSIN1,BCAR1,NEB,SH3KBP1 |
| 1.258e-02 | -4.38 | cation homeostasis | biological process | GO:0055080 | 536 | 71 | 16441 | 1675 |
CCDC109B,EPAS1,ATP2C2,HEXB,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,SLC9A7,ATP6V0B,APLP2,SCNN1A,PLCG2,STEAP2,TRPC1,CNNM4,RAB20,TMEM64,SLC39A10,F2R,CHP1,CLCN3,CD55,ACO1,SLC11A2,ATP1B1,RAB38,CD40,ITPR3,EDNRA,ATP13A2,ATP1A1,WFS1,SLC9A6,ATP7B,INPP4B,F2RL1,MTL5,CALB2,SLC25A27,ABCG2,SLC9A2,NEO1,CA2,GATA2,BAX,SGK3,SGK1,TMBIM6,SLC12A2,ATP2B1,MFI2,ERO1A,GRIN1,TTC7A,EIF2AK1,NUBP1,SFXN5,STEAP1,FECH,SWAP70,SLC4A4,ITPR1,SLC4A3,ATP1B3,MCUR1,GPER1,JAK3,NDFIP1,CYBRD1 |
| 1.261e-02 | -4.37 | calmodulin binding | molecular function | GO:0005516 | 178 | 28 | 16491 | 1673 |
MYO5B,SCN5A,CAMSAP3,ADD1,SNTB2,ASPM,CAMKK1,IQGAP1,GRIN1,CAMK1D,SNTB1,DAPK2,SNTA1,MAPKAPK2,ADD3,MAP2,CALD1,KCNN4,DAPK1,MYH14,GEM,IQGAP3,PHKA2,ITPKA,NRGN,MYO5A,ATP2B1,CTH |
| 1.264e-02 | -4.37 | Hirschsprung's disease(PMID:19196962) | GWAS genes | Hirschsprung's disease(PMID:19196962) | 2 | 2 | 2389 | 269 |
NRG1,RET |
| 1.264e-02 | -4.37 | Nephrolithiasis(PMID:22396660) | GWAS genes | Nephrolithiasis(PMID:22396660) | 2 | 2 | 2389 | 269 |
DGKH,RGS14 |
| 1.265e-02 | -4.37 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 182 | 28 | 17758 | 1761 |
PLA2G4A,MX1,SEC23A,AVPI1,RUNX2,HLA-E,EPS8,SLC11A2,IL18,ITPR2,IDH1,APC2,PHLDA1,FGF19,FAS,MDK,PLK2,CSF1,IL6ST,A4GALT,LRIG1,KLF3,BCL6,SGK1,NFKBIZ,ERBB3,ARL4D,CYP1B1 |
| 1.265e-02 | -4.37 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 182 | 28 | 17758 | 1761 |
CMAS,ING1,TXN,HPS3,UGP2,ADD1,PQLC3,NLRX1,GUSB,RPS6KA1,S100A4,EIF2AK1,RAB6A,DHX32,DGKH,CPNE2,NGFRAP1,KCNN4,DBI,CD9,FAM195A,RAB20,SERPINB6,DLG3,CEP41,C12orf75,NUP85,S100A6 |
| 1.265e-02 | -4.37 | REACTOME_SIGNALING_BY_RHO_GTPASES | MSigDB lists | REACTOME_SIGNALING_BY_RHO_GTPASES | 111 | 19 | 17758 | 1761 |
ARHGAP11A,RASGRF1,ARAP2,ARHGEF3,ARAP3,RHOA,ARHGEF11,RALBP1,ARHGDIB,ARHGEF16,ABR,ARHGAP35,ARHGAP24,FAM13B,RHOBTB2,TIAM1,ARHGEF9,FGD1,ARHGEF4 |
| 1.265e-02 | -4.37 | CTGYNNCTYTAA_UNKNOWN | MSigDB lists | CTGYNNCTYTAA_UNKNOWN | 81 | 15 | 17758 | 1761 |
ZNF462,ITGA3,PELI2,FXYD3,OTUB2,DAB2IP,OSR2,EPHA1,DLG3,LDB2,BTBD3,NRGN,NR3C2,NRP2,MECOM |
| 1.270e-02 | -4.37 | magnesium ion binding | molecular function | GO:0000287 | 194 | 30 | 16491 | 1673 |
PGM1,PINK1,ENO2,FIGNL1,RPS6KA1,ATP9A,GCLC,ATP8A1,PIF1,ATP8B3,IDH1,ATP10D,MAP3K6,NCS1,TOP2A,WEE1,NUDT16,RPS6KA2,STK26,PTEN,ALPP,IMPAD1,STK38,PRPS2,SRR,ATP8B1,GEM,MAP3K5,MAST4,MAPK12 |
| 1.271e-02 | -4.37 | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | 174 | 27 | 17758 | 1761 |
IGFBP6,PRSS23,SSH1,ETV5,HABP4,SDC4,HERC5,ATP1B1,NTAN1,PHLDA1,ANTXR1,BMP2K,OPTN,BCAR3,AKIRIN1,RCN1,RPS6KA2,NR1D2,ERAP1,TACSTD2,HLA-C,ARPC2,ABCA1,ABCG1,ARHGEF4,NXT2,LAMP3 |
| 1.272e-02 | -4.36 | cell redox homeostasis | biological process | GO:0045454 | 58 | 12 | 16441 | 1675 |
DNAJC10,TXN,GCLC,TMX4,ERO1A,PDIA5,PDIA3,AIFM3,TXNDC11,PDIA6,PDIA4,PRDX4 |
| 1.272e-02 | -4.36 | regulation of response to oxidative stress | biological process | GO:1902882 | 58 | 12 | 16441 | 1675 |
SIRT1,SESN3,TXN,PINK1,FBLN5,AKT1,STK26,BMP7,NR4A3,HDAC6,SESN1,HSPB1 |
| 1.272e-02 | -4.36 | tetrapyrrole metabolic process | biological process | GO:0033013 | 58 | 12 | 16441 | 1675 |
FECH,CYP1A1,BLVRB,NFE2L1,MMADHC,SLC11A2,EIF2AK1,BLVRA,SLC25A38,SPTB,ABCC1,ABCD4 |
| 1.274e-02 | -4.36 | GRADE_COLON_AND_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_UP | 273 | 39 | 17758 | 1761 |
LAMP1,HJURP,DCAF7,SOX9,KIF23,DHX8,GTF3A,GDF15,GPSM2,CCNB1,CCDC92,RCN1,GTF2F2,FXYD5,AHCY,SLC12A2,ETV4,SEPHS1,CKS2,PLK1,PMPCB,ZNF84,GCLC,SPATA13,GLO1,NUSAP1,TCF7,PDK3,BORA,CDK1,RHEB,PRDX4,CARHSP1,ETS2,KBTBD2,NMI,AURKA,TRAF5,MELK |
| 1.274e-02 | -4.36 | negative regulation of dephosphorylation | biological process | GO:0035305 | 79 | 15 | 16441 | 1675 |
CAMSAP3,SPRED1,LMTK3,SWAP70,PPP4R4,SEMA4D,IQGAP1,CRY2,PKMYT1,DLG3,TIPRL,SH2D4A,SYTL2,ARFGEF3,CHP1 |
| 1.274e-02 | -4.36 | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP | MSigDB lists | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP | 166 | 26 | 17758 | 1761 |
PRKAA2,EPAS1,FRMD6,SERTAD4,LITAF,CCDC68,RNF182,FAM101B,FOS,CYP4F3,TMCC3,KDM4D,MAN2A2,DAPK2,SS18,ITGB8,PPP4R1,RUNDC3B,PIK3CA,ATP8B1,VAT1,DAB2IP,NTN4,F2RL1,SYTL3,GPR161 |
| 1.274e-02 | -4.36 | GCATTTG,MIR-105 | MSigDB lists | GCATTTG,MIR-105 | 166 | 26 | 17758 | 1761 |
AMOTL2,PHF20L1,NF2,COQ10B,ITGA6,EPHA4,MIER3,TEX2,MORF4L2,FNDC3A,TP53INP2,SP4,FZD7,CXXC4,KLF12,FRAS1,AMMECR1,RAP2C,BMP1,CDKN1B,TNFRSF12A,GAD1,TIPARP,MYLIP,ARHGEF9,SOCS5 |
| 1.275e-02 | -4.36 | TCCATTKW_UNKNOWN | MSigDB lists | TCCATTKW_UNKNOWN | 223 | 33 | 17758 | 1761 |
SPRED1,HSPG2,CHCHD7,DDIT4L,ETV5,FTH1,BCL2L1,BEX2,SCML1,CCDC92,ATP6V0B,TSPAN6,DPYSL2,CALD1,CABP1,IL6ST,LMO4,DUSP10,TSPAN13,CACNA1D,DLG3,CCDC88A,TACC1,NR3C1,NR4A1,ITCH,PTGFRN,MAP2,NR4A3,AURKA,ZNF502,NR2C2,JARID2 |
| 1.275e-02 | -4.36 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | 223 | 33 | 17758 | 1761 |
MAN2B2,PCOLCE,CEP70,IL15RA,ENO2,PDIA5,PKP2,EFHD2,CYB561,SH3KBP1,KIAA1161,ABCD4,C16orf74,ELMO2,GATA2,ELF5,ABCA2,CRY2,KLF9,EPB41L4B,RAB27B,MYBL1,GCLC,SPATA13,TXNDC11,ATP13A2,NIN,P4HA2,SERPINB1,EGLN1,USP43,EHD1,JARID2 |
| 1.280e-02 | -4.36 | positive regulation of defense response | biological process | GO:0031349 | 391 | 54 | 16441 | 1675 |
DDX58,LAMP1,IL15,RPS6KA1,HLA-E,PSME2,CALM3,PSMD10,PSME1,IL18,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,PIK3AP1,IL6ST,PLCG2,MAPK11,SCARA3,LGMN,CNPY3,SYK,RASGRP1,SMAGP,KLK5,PLSCR1,RIPK2,PSMB4,TNIP1,ITCH,CALM1,PTGER4,F12,ITPR3,DUSP4,ELK1,FOS,PSMA4,MAPKAPK2,CTSL,GPRC5B,CDK19,PVRL2,PELI2,ITPR1,NFKBIA,NOD2,NLRC5,KLK7,IRF7,F2RL1,IFIH1,TMEM173 |
| 1.280e-02 | -4.36 | protein localization to nucleus | biological process | GO:0034504 | 154 | 25 | 16441 | 1675 |
SUN1,SUN2,HES1,SEC61B,AKT1,SOX9,PIK3R1,SYNE2,TP53,PRICKLE1,PDIA3,PYGO1,DAG1,ZFYVE9,LMNA,SIX4,BMP7,NFKBIA,BCL6,PIKFYVE,JAK3,F2R,SYK,TOB1,NUP85 |
| 1.283e-02 | -4.36 | positive regulation of cell development | biological process | GO:0010720 | 442 | 60 | 16441 | 1675 |
BIN1,GRN,FOXO6,SERPINE2,EPHA4,RET,ETV5,CAMK1D,CRABP2,TEAD3,GRM5,ITGA3,GATA2,IL6ST,MEGF8,BMP7,BCL6,BAX,DAB2IP,TWIST1,TNFRSF12A,WNT3A,PACSIN1,TIAM1,RIMS2,TLE6,EPB41L5,HES1,TGIF1,TIMP2,RHOA,MMD,ASPM,RAPGEF2,RGCC,PDE5A,HMG20B,RHEB,ARHGAP35,DPYSL3,GPRC5B,SEMA4D,BHLHB9,TMEM30A,CSF1,LIMK1,PTK7,TRIOBP,AURKA,EFNA5,NRG1,GPER1,ARPC2,ITPKA,SOX8,RGS14,ARSB,SEMA3A,COBL,L1CAM |
| 1.283e-02 | -4.36 | Gastric cancer network 2 | WikiPathways | WP2363 | 34 | 9 | 4455 | 516 |
TOP2A,COL9A3,UBE2T,TP53,RAD17,UBE2C,LBR,S100A6,FANCI |
| 1.283e-02 | -4.36 | oligoastrocytoma_Grade_III | COSMIC cancer mutations | oligoastrocytoma_Grade_III | 274 | 39 | 17775 | 1757 |
VANGL1,RET,XYLT1,TP53,ERBB2,TEX2,HDAC6,PHLDA1,PARM1,PPP2R3A,TMEM63A,CDKN2C,MUC16,MDM1,FRY,PTEN,ELF5,EXOC8,PIK3CA,CRTAP,FARP2,AKT1,MICB,RC3H2,PIK3R1,OGDHL,PYGO1,IDH1,GNA11,GNAS,RBM47,CORO1C,NLRC5,CSTF2,ARRB1,ZMIZ1,ABCA1,MELK,TLL2 |
| 1.285e-02 | -4.35 | NAKAMURA_ADIPOGENESIS_LATE_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_UP | 96 | 17 | 17758 | 1761 |
ACACB,ELK3,MMD,PRSS23,XYLT1,PRKAR2B,GLT8D2,STX3,CDKN2C,TFAP4,IRS2,PPP2R5A,NPTXR,ABCA1,CYBRD1,GM2A,CKS2 |
| 1.289e-02 | -4.35 | regulation of plasma membrane organization | biological process | GO:1903729 | 72 | 14 | 16441 | 1675 |
KIF5B,LZTFL1,SORBS1,ITGA3,PPP2R5A,AKT1,PIK3R1,DLG1,EZR,GPER1,BCL2L1,ARF6,ARHGEF16,STX3 |
| 1.290e-02 | -4.35 | negative regulation of cell projection organization | biological process | GO:0031345 | 131 | 22 | 16441 | 1675 |
SEMA6B,RHOA,CIT,RAPGEF2,EPHA4,LRP4,CDK5R1,DPYSL3,ARHGAP24,ITGA3,SEMA4D,PTEN,PLK2,KIAA0319,TACSTD2,SEMA3G,WNT3A,ARF6,SEMA3A,RAP1GAP,SPRY2,SEMA3B |
| 1.290e-02 | -4.35 | glutamine family amino acid metabolic process | biological process | GO:0009064 | 65 | 13 | 16441 | 1675 |
GFPT1,GCLM,PRODH,ALDH5A1,GCLC,HAL,GGH,GOT1,SLC1A3,OAT,GAD1,AMDHD1,FAH |
| 1.290e-02 | -4.35 | positive regulation of JUN kinase activity | biological process | GO:0043507 | 65 | 13 | 16441 | 1675 |
FZD4,EPHA4,MAP3K9,DAB2IP,MDFIC,PKN1,FZD5,MAP3K5,SYK,MAP3K6,GAB1,DVL2,MDFI |
| 1.291e-02 | -4.35 | negative regulation of lymphocyte mediated immunity | biological process | GO:0002707 | 32 | 8 | 16441 | 1675 |
HLA-B,HLA-E,BCL6,NOD2,TAP1,C10orf54,NDFIP1,HLA-A |
| 1.291e-02 | -4.35 | regulation of natural killer cell mediated cytotoxicity | biological process | GO:0042269 | 32 | 8 | 16441 | 1675 |
LAMP1,HLA-B,PVRL2,HLA-E,TAP1,HLA-A,RASGRP1,SMAGP |
| 1.291e-02 | -4.35 | reproductive behavior | biological process | GO:0019098 | 32 | 8 | 16441 | 1675 |
THRB,GRN,APLP2,SERPINE2,PTEN,THRA,HEXB,GRIN1 |
| 1.291e-02 | -4.35 | osteoclast differentiation | biological process | GO:0030316 | 32 | 8 | 16441 | 1675 |
CD109,OSTM1,CSF1,MITF,GLO1,LRRK1,SNX10,FARP2 |
| 1.294e-02 | -4.35 | human chr11q21 | chromosome location | human chr11q21 | 36 | 7 | 26250 | 1887 |
ENDOD1,CCDC82,MAML2,SLC36A4,SESN3,SMCO4,KDM4D |
| 1.295e-02 | -4.35 | MODULE_136 | MSigDB lists | MODULE_136 | 454 | 60 | 17758 | 1761 |
LMO7,UNKL,LMTK3,CDH22,AASS,MRPS15,TP53,SLC25A27,C6orf106,CTSZ,ISYNA1,NANS,BARD1,IL18R1,CMTM6,C9orf69,TYMP,CYP1A1,RNF220,RALGPS2,CDK16,UBE2J1,CD9,ESPN,PDE4D,SCARA3,FAR2,CITED2,ATG4D,AMOTL2,TBC1D8B,FMN1,ADCK3,MICB,MYBL2,PIP4K2C,FURIN,TMEM144,DIAPH2,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,GALNT3,PTPRF,AMZ2,ENPP1,NEIL1,SLC9A6,CSF1,PLEKHG1,S100A5,FGD6,TMEM120A,PKIA,RRAGD,PCSK5 |
| 1.301e-02 | -4.34 | negative regulation of cell activation | biological process | GO:0050866 | 162 | 26 | 16441 | 1675 |
CASP3,SERPINE2,LGALS3,INPP5D,ITCH,UBASH3B,PDE5A,ERBB2,CD274,PKN1,PDGFB,MERTK,ABR,FAS,PDGFA,BANK1,AXL,IL31RA,BCL6,PRKG1,DLG1,GPER1,C10orf54,NDFIP1,JAK3,SOCS5 |
| 1.304e-02 | -4.34 | HS-GAG biosynthesis | REACTOME pathways | R-HSA-2022928 | 31 | 8 | 8202 | 867 |
HS6ST1,SLC35D2,HSPG2,SDC4,HS3ST3B1,SDC1,NDST3,GLCE |
| 1.304e-02 | -4.34 | Molecules associated with elastic fibres | REACTOME pathways | R-HSA-2129379 | 31 | 8 | 8202 | 867 |
LTBP1,FBLN5,ITGB8,BMP7,ITGAV,LTBP2,FBLN1,LTBP3 |
| 1.307e-02 | -4.34 | blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | blastic_plasmacytoid_dendritic_cell_neoplasm | 67 | 13 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,GATA2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 1.308e-02 | -4.34 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | 74 | 14 | 17758 | 1761 |
ARHGEF10L,LMO7,LRRFIP2,CPEB4,ETS2,RAPGEF2,FOSB,PIK3R1,SORL1,DOCK5,ZFAND5,SLC20A1,LEPR,NCOA2 |
| 1.312e-02 | -4.33 | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | 33 | 8 | 17775 | 1757 |
SS18,AKT1,FGFR2,RET,PIK3R1,PIK3CA,ERBB2,IDH1 |
| 1.312e-02 | -4.33 | liver-other-hepatoblastoma | COSMIC cancer mutations | liver-other-hepatoblastoma | 33 | 8 | 17775 | 1757 |
GNAS,CDKN2C,AKT1,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 1.312e-02 | -4.33 | desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | desmoplastic_small_round_cell_tumour | 33 | 8 | 17775 | 1757 |
SS18,AKT1,FGFR2,RET,PIK3R1,PIK3CA,ERBB2,IDH1 |
| 1.312e-02 | -4.33 | hepatoblastoma | COSMIC cancer mutations | hepatoblastoma | 33 | 8 | 17775 | 1757 |
GNAS,CDKN2C,AKT1,PIK3R1,PIK3CA,TP53,ERBB2,IDH1 |
| 1.316e-02 | -4.33 | ZHAN_MULTIPLE_MYELOMA_MS_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MS_UP | 46 | 10 | 17758 | 1761 |
SERPINE2,NGFRAP1,KLHL13,MITF,CST3,RUNDC3B,PPM1H,MYRIP,SPRY2,PCSK5 |
| 1.316e-02 | -4.33 | KEGG_N_GLYCAN_BIOSYNTHESIS | MSigDB lists | KEGG_N_GLYCAN_BIOSYNTHESIS | 46 | 10 | 17758 | 1761 |
MAN2A2,DDOST,DOLPP1,ALG13,MGAT4A,FUT8,MGAT4B,RPN2,MGAT5B,MGAT5 |
| 1.316e-02 | -4.33 | SESTO_RESPONSE_TO_UV_C5 | MSigDB lists | SESTO_RESPONSE_TO_UV_C5 | 46 | 10 | 17758 | 1761 |
HES1,IQGAP1,PPP4R1,SDC4,PBX3,WWP1,YES1,TIAM1,RASA1,ABCC1 |
| 1.322e-02 | -4.33 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | 53 | 11 | 17775 | 1757 |
PLCG1,JAK1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,PRICKLE1,ERBB2,JAK3 |
| 1.322e-02 | -4.33 | mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | mycosis_fungoides-Sezary_syndrome | 53 | 11 | 17775 | 1757 |
PLCG1,JAK1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,PRICKLE1,ERBB2,JAK3 |
| 1.322e-02 | -4.33 | stomach-carcinoma-undifferentiated_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-undifferentiated_adenocarcinoma | 53 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 1.322e-02 | -4.33 | undifferentiated_adenocarcinoma | COSMIC cancer mutations | undifferentiated_adenocarcinoma | 53 | 11 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3 |
| 1.322e-02 | -4.33 | smooth_muscle | COSMIC cancer mutations | smooth_muscle | 53 | 11 | 17775 | 1757 |
GNAS,CDKN2C,SS18,CDH1,JAK1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1 |
| 1.322e-02 | -4.33 | KINESIN_MOTOR_2 | prosite domains | PS50067 | 44 | 10 | 11866 | 1235 |
KIF5B,KIF20A,KIFC2,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 1.324e-02 | -4.32 | Glycosaminoglycan degradation | KEGG pathways | ko00531 | 19 | 6 | 6908 | 758 |
GNS,HPSE,ARSB,GUSB,GALNS,HEXB |
| 1.324e-02 | -4.32 | Glycosaminoglycan degradation | KEGG pathways | hsa00531 | 19 | 6 | 6908 | 758 |
GNS,HPSE,GUSB,ARSB,GALNS,HEXB |
| 1.324e-02 | -4.32 | RasGAP | smart domains | SM00323 | 14 | 5 | 9131 | 997 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 1.325e-02 | -4.32 | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | 60 | 12 | 17775 | 1757 |
GNAS,NF2,CDH1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,JAK3 |
| 1.327e-02 | -4.32 | superpathway of inositol phosphate compounds | BIOCYC pathways | HUMAN_PWY-6371 | 66 | 15 | 907 | 115 |
PLCG1,PLCH1,PTEN,TMEM55B,INPP5D,PIK3R1,PLCG2,PIP4K2C,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,MINPP1,PLCB2 |
| 1.329e-02 | -4.32 | protein N-linked glycosylation via asparagine | biological process | GO:0018279 | 178 | 28 | 16441 | 1675 |
GFPT1,SEC23A,CMAS,MGAT4B,GNE,PDIA3,CTSZ,COL7A1,NANS,B4GALT4,MCFD2,MAN2A2,FUCA1,UAP1,DDOST,SERPINA1,CTSC,ALG13,MGAT4A,DOLPP1,FUT8,UBE2J1,RPN2,CTSA,LMAN1,ST3GAL1,MGAT5,PPP6R1 |
| 1.330e-02 | -4.32 | GSE17721_LPS_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDM_UP | 199 | 30 | 17758 | 1761 |
PVRL4,SPRED1,RUNX2,PARP12,UPF3B,PLSCR1,IL15,AASS,NR3C1,C5orf30,RAB38,PDK3,ATP1B1,SAV1,FNDC3A,TNFSF9,PSIP1,APPBP2,CHPF,ARHGAP35,ACADSB,RBL1,MDFIC,STK39,PIM1,SGCB,ISOC1,TMEM9,JARID2,PARP9 |
| 1.333e-02 | -4.32 | V$COUP_DR1_Q6 | MSigDB lists | V$COUP_DR1_Q6 | 232 | 34 | 17758 | 1761 |
BCAM,HDAC11,TP53,ERBB2,CRABP2,C3orf18,PRKACA,FBLN1,SYTL2,CYP26A1,SS18,CDK16,RRBP1,IQCD,SMYD5,TPCN1,NR2C1,ATP2B1,LAMP2,LONRF3,NR4A1,KLK6,SLC11A2,F12,BSDC1,PGF,C19orf66,NR4A3,OVOL1,EIF4EBP2,MRPS28,ARF6,HOXC13,DIS3L |
| 1.333e-02 | -4.32 | V$FOXO1_01 | MSigDB lists | V$FOXO1_01 | 232 | 34 | 17758 | 1761 |
IER5L,BIN1,LASP1,BMF,CDKN1C,CHCHD7,THRA,ETV5,ARFGEF1,ZNF385B,SCML1,FOXP2,CCND1,SESN3,CYR61,LMO4,MITF,PLCB2,TRIM8,RGAG1,C2orf69,LRRC1,ITPR3,H2AFV,NFIB,NFIX,PITX2,KLF12,NR4A2,EIF4EBP2,NRG1,C1orf43,OSR1,NR2C2 |
| 1.337e-02 | -4.32 | PID_EPO_PATHWAY | MSigDB lists | PID_EPO_PATHWAY | 33 | 8 | 17758 | 1761 |
IRS2,PLCG1,INPP5D,PLCG2,PIK3R1,BCL2L1,GAB1,SOCS3 |
| 1.337e-02 | -4.32 | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | 33 | 8 | 17758 | 1761 |
CD99,PRKAG2,MBP,ADCK3,BCL6,TCF7,IDH1,CTH |
| 1.337e-02 | -4.32 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | MSigDB lists | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | 33 | 8 | 17758 | 1761 |
SEC23A,MGAT4A,FUT8,MGAT4B,LMAN1,B4GALT4,MCFD2,MGAT5 |
| 1.337e-02 | -4.32 | CHROMOSOME_SEGREGATION | MSigDB lists | CHROMOSOME_SEGREGATION | 33 | 8 | 17758 | 1761 |
TOP2A,REC8,ZWINT,CDCA5,NDC80,NUSAP1,CENPE,ESPL1 |
| 1.339e-02 | -4.31 | Folic Acid Network | WikiPathways | WP1311 | 2 | 2 | 4455 | 516 |
TXN,FMN1 |
| 1.339e-02 | -4.31 | Folic Acid Network | WikiPathways | WP1273 | 2 | 2 | 4455 | 516 |
TXN,FMN1 |
| 1.339e-02 | -4.31 | Folic Acid Network | WikiPathways | WP1075 | 2 | 2 | 4455 | 516 |
TXN,FMN1 |
| 1.339e-02 | -4.31 | PDGF Pathway | WikiPathways | WP2526 | 2 | 2 | 4455 | 516 |
PDGFA,PDGFB |
| 1.340e-02 | -4.31 | GNF2_BNIP3L | MSigDB lists | GNF2_BNIP3L | 67 | 13 | 17758 | 1761 |
MARCH8,FECH,CA2,ERMAP,H1F0,GCLC,MPP1,BLVRB,FBXO9,EIF2AK1,SPTB,TRAK2,RAD23A |
| 1.342e-02 | -4.31 | phospholipid scramblase activity | molecular function | GO:0017128 | 10 | 4 | 16491 | 1673 |
ANO9,PLSCR1,ANO4,ANO6 |
| 1.342e-02 | -4.31 | GDP-dissociation inhibitor activity | molecular function | GO:0005092 | 10 | 4 | 16491 | 1673 |
ARHGDIB,RGS14,RANBP1,SH3BP4 |
| 1.344e-02 | -4.31 | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | 191 | 29 | 17758 | 1761 |
CENPI,DGKQ,ETV5,EZR,FBXO9,MGST2,PDK3,TRIB2,GTF2A2,FAM101B,ARSK,CASP4,PSIP1,CYP26A1,FANCI,OPTN,MESDC2,CTGF,COQ10A,CDH1,ZNF823,TWSG1,REEP1,DRAM1,CD9,SERPINB6,ALDH7A1,ALS2CL,RBMS2 |
| 1.344e-02 | -4.31 | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | 191 | 29 | 17758 | 1761 |
TTC39B,PPM1J,PSME2,CPT2,MPP1,CAST,ARMC7,DIAPH2,SEPP1,REPS1,AIP,KIAA1161,ABR,CHPF,APOBEC3B,DAPK2,ATP6V0B,TAPBP,RPL12,KLF12,CDK16,SLC16A6,RPL39,LIMK1,RRBP1,NR4A2,C10orf54,TECR,MGAT5 |
| 1.344e-02 | -4.31 | GSE17721_POLYIC_VS_CPG_24H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDM_UP | 191 | 29 | 17758 | 1761 |
IL15RA,ST14,HEBP1,MPP1,BCL9,RASA2,CBX6,GGH,SYTL4,SNN,SAV1,SPTLC2,MERTK,RNPEP,FGF19,NFIX,SESN3,ADD3,MATN2,ARRDC1,IRF2,GOT1,LRRK1,RELL1,CNOT6L,USF2,MYL12B,SCN3A,TMEM131 |
| 1.344e-02 | -4.31 | GSE27786_CD8_TCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKTCELL_DN | 191 | 29 | 17758 | 1761 |
LAMP2,MX1,ARAP3,PLSCR1,PPM1J,RASA2,CD82,TEX2,TMEM170B,FZD6,FRMD4B,GABARAPL1,KDM4D,GNAS,CARHSP1,DOPEY2,AGPAT2,PPP4R1,RUNDC3B,UBE2J1,SORL1,WWP1,HMGA1,RELL1,GEM,TECR,ARPC2,LIFR,TMEM173 |
| 1.344e-02 | -4.31 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | 191 | 29 | 17758 | 1761 |
CCDC109B,EPAS1,SPATA13,NANS,PKMYT1,NCKAP1,DOCK5,PDIK1L,SYTL2,RASGRP2,ATP13A2,CTNNBIP1,ENDOD1,DAPK2,PRKAG2,CDK19,VASN,OSBPL3,TRAF3IP1,AIM1,RRBP1,AGFG2,CACNA1D,TMEM120A,L1CAM,SYTL3,NEB,XKR8,ATG4D |
| 1.344e-02 | -4.31 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | 191 | 29 | 17758 | 1761 |
LZTFL1,ALDH2,ARMCX3,FAM199X,ARHGEF11,ATP8A1,BCL9,PLAUR,PLEKHO1,FAM134A,PRICKLE1,KIF13A,SNN,SEPP1,SESN1,C3orf58,KCTD9,XKRX,PTPRF,OTUD1,TMEM164,AP1AR,TWSG1,CTSC,FAM13B,DAPK1,BRI3,MGAT5,ZBTB33 |
| 1.344e-02 | -4.31 | GSE17721_0.5H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_POLYIC_BMDM_UP | 191 | 29 | 17758 | 1761 |
ANXA3,SHMT1,AVPI1,GUSB,HEBP1,DNAJC3,CDC20,FURIN,MYBL2,DNAJB11,NDRG2,GDF15,FAM81A,SEPP1,STIL,SESN1,NUBP1,DAG1,PGF,FGFR2,MMP17,CGREF1,NKD1,DAPK1,OPN3,AKR1B1,PRIMA1,MAFF,NUP85 |
| 1.344e-02 | -4.31 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 191 | 29 | 17758 | 1761 |
SEC23A,CDK17,ALDH2,ERMAP,PSMB4,NFKBIE,MRPS15,TBC1D1,TSC22D3,DAP,CALM1,PBX3,CALM3,DNAJB14,DHRS3,H2AFV,MYL12A,BCAR3,CALM2,PIAS3,KCNN4,STK38,DAPK1,NOD2,BCL6,GRAMD1C,SLC25A38,F2R,ACOT7 |
| 1.344e-02 | -4.31 | GSE3982_NEUTROPHIL_VS_TH2_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_DN | 191 | 29 | 17758 | 1761 |
PLA2G4A,MMD,CENPI,ATP8A1,PTTG1,GNE,NUSAP1,GTF3A,HES2,LACTB2,MGST2,PSMA4,LRRC42,RCN1,OSBPL3,PTER,PASK,OTUB2,MAPK11,DIXDC1,LMAN1,COL16A1,ESPL1,ACOT7,OCLN,METAP2,TMEM131,CKS2,FAM69A |
| 1.344e-02 | -4.31 | positive regulation of nervous system development | biological process | GO:0051962 | 409 | 56 | 16441 | 1675 |
BIN1,GRN,WASF3,FOXO6,SERPINE2,EPHA4,RET,ETV5,CAMK1D,CRABP2,SRPX2,GRM5,ADGRB2,ITGA3,GATA2,IL6ST,MEGF8,BMP7,FLRT3,BCL6,DAB2IP,TNFRSF12A,WNT3A,PACSIN1,TIAM1,RIMS2,TLE6,HES1,TGIF1,TIMP2,RHOA,MMD,ASPM,RAPGEF2,CDC20,HMG20B,RHEB,ARHGAP35,DPYSL3,GPRC5B,SEMA4D,BHLHB9,TMEM30A,CSF1,LIMK1,PTK7,EFNA5,NRG1,GPER1,ITPKA,SOX8,RGS14,ARSB,SEMA3A,COBL,L1CAM |
| 1.345e-02 | -4.31 | AHCY (adenosylhomocysteinase) | protein interactions | 191 | 62 | 13 | 16036 | 1726 |
SIRT1,HLA-B,LGALS3,PAPSS1,CUL4B,TRAF3IP1,AHCY,SERPINB6,FBXO6,HSPB1,H2AFV,SDC1,APPBP2 |
| 1.345e-02 | -4.31 | KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) | protein interactions | 3815 | 62 | 13 | 16036 | 1726 |
SPRED1,PLCG1,PTPRU,CD63,INPP5D,PIK3R1,CD9,TEC,YES1,JAK3,RASA1,SH3KBP1,SOCS5 |
| 1.345e-02 | -4.31 | NAD-dependent histone deacetylase activity | molecular function | GO:0017136 | 15 | 5 | 16491 | 1673 |
SIRT1,HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.345e-02 | -4.31 | intracellular calcium activated chloride channel activity | molecular function | GO:0005229 | 15 | 5 | 16491 | 1673 |
ANO9,ANO4,TTYH3,ANO1,ANO6 |
| 1.346e-02 | -4.31 | positive regulation of epithelial cell migration | biological process | GO:0010634 | 94 | 17 | 16441 | 1675 |
EPB41L5,ANXA3,AKT1,SOX9,HDAC6,PDGFB,ETS1,BCAR1,SRPX2,NRP2,HDAC9,GPLD1,PLCG1,ITGA3,PLPP3,EPB41L4B,HSPB1 |
| 1.346e-02 | -4.31 | regulation of transcription factor import into nucleus | biological process | GO:0042990 | 94 | 17 | 16441 | 1675 |
DDX58,RHOA,NFKBIE,THRA,PIK3R1,LITAF,RAB23,PSMD10,PRKCQ,IL18,IL18R1,NOV,CDH1,BMP7,NFKBIA,TMEM173,MDFI |
| 1.348e-02 | -4.31 | positive regulation of protein dephosphorylation | biological process | GO:0035307 | 45 | 10 | 16441 | 1675 |
CALM2,PINK1,ADORA1,PPP2R5A,NPNT,CALM1,CALM3,CDCA2,SLC39A10,GPLD1 |
| 1.352e-02 | -4.30 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | 53 | 11 | 17758 | 1761 |
IL17RB,ALDH5A1,CYP1A1,CDK17,ISYNA1,FHL1,SNN,F2RL1,F2R,HSPB1,MECOM |
| 1.352e-02 | -4.30 | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | MSigDB lists | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | 53 | 11 | 17758 | 1761 |
CALM2,PLCG1,ADRBK1,FGFR2,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,FGF19 |
| 1.352e-02 | -4.30 | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | MSigDB lists | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | 53 | 11 | 17758 | 1761 |
PODXL2,FAM46A,CTGF,CYR61,FZD4,NR4A1,CXorf57,CLDN4,LTBP2,ETAA1,CPPED1 |
| 1.352e-02 | -4.30 | PID_AR_TF_PATHWAY | MSigDB lists | PID_AR_TF_PATHWAY | 53 | 11 | 17758 | 1761 |
SIRT1,SMARCA2,NR3C1,GATA2,HDAC1,HOXB13,PKN1,NR2C1,NCOA2,APPBP2,NR2C2 |
| 1.353e-02 | -4.30 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1157 | 137 | 17775 | 1757 |
LTBP1,HECA,PPP4R4,TTC39B,DNAJC3,CA8,CARD10,TMC1,SLC9A7,SH3KBP1,ZFYVE16,ANKFN1,ABCA2,POF1B,ATRNL1,MARCH2,ANO4,TLN2,TRAM1,ZNF462,SPATA18,SNTB2,ITCH,PPP1R14C,ADRBK2,ABR,OPTN,CXXC4,TRIM9,ZNF114,ARHGEF19,FAM110C,ZNF165,HDAC1,PIEZO1,LEMD1,UNC5B,CPPED1,CDK17,FRMD4A,MTL5,CNTNAP2,PM20D2,TNFRSF19,DHRS3,FBLN1,UBE2Q2,IGF1R,FAM189A1,FRAS1,AIM1,COL6A1,PRKG1,MAP3K9,FAR2,DGKG,SYTL3,SALL4,MICB,LPGAT1,RANBP9,CYB5A,FAS,SLC4A3,KLK7,PER3,SEMA3A,AFAP1,DOCK9,ARHGAP11A,LMO7,NCKAP5,TPRN,MTM1,DLGAP5,TCTN2,CCDC110,TP53,MRAS,APC2,SYTL2,APPBP2,TTC21B,SS18,MUC16,WDR44,ZDHHC12,BCL6,RTKN2,ECE1,MYT1,SULF2,MYO5B,DOCK4,CAMSAP3,UTRN,ALCAM,ARHGAP35,CDK19,PLEKHG1,TLE1,C1orf43,SLC25A30,COBL,CCNJL,PBX3,SELL,ETS1,SLC25A43,LGALS3BP,C16orf74,MLPH,PTEN,GTF2F2,SGCB,MYO5A,DLGAP1,NFE2L3,RAPGEF2,PIK3R1,MBNL3,DIAPH2,BLVRA,LRRC1,GRTP1,CRISPLD2,FUCA1,SWAP70,BANK1,FAT4,PPM1H,ARSB,L1CAM,ZBTB33,DCBLD1,CD33,GOLGB1 |
| 1.354e-02 | -4.30 | response to hypoxia | biological process | GO:0001666 | 267 | 39 | 16441 | 1675 |
CASP3,PINK1,NKX3-1,SLC2A4,EPAS1,TP53,ITPR2,CCNB1,PDGFB,ETS1,LMNA,CYP1A1,ADORA1,PTEN,BMP7,VASN,CST3,CDKN1B,AHCY,TWIST1,CITED2,EGLN3,SIRT1,RHOA,AKT1,RGCC,PPARA,PRKCQ,SLC11A2,LOXL2,PDK3,ATP1B1,EDNRA,SOCS3,PLOD2,ITPR1,NR4A2,CPEB2,EGLN1 |
| 1.356e-02 | -4.30 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | 183 | 28 | 17758 | 1761 |
SYPL1,MRPS33,ALDH2,UGP2,TBC1D1,DAP,RALBP1,SYBU,FAM134A,ARFGEF1,C1GALT1C1,C6orf106,NENF,HDAC6,GSTP1,PSIP1,FAS,STK17A,SNTA1,AMZ2,WEE1,NEIL1,C7orf49,CDK19,PLK4,UBE2J1,TIAM1,ABCC1 |
| 1.356e-02 | -4.30 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | 183 | 28 | 17758 | 1761 |
ARHGEF3,PACSIN2,MBP,UGT8,NUAK1,BCL9,RALBP1,THRA,XYLT1,MRS2,MBNL3,TESK2,GTF3A,NUP62CL,SESN1,MARCH8,AMZ2,PPP2R5A,KIF13B,OSBPL3,ABCB1,STK39,CABIN1,RAB27B,PER3,TIPARP,TOB1,JARID2 |
| 1.356e-02 | -4.30 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | 183 | 28 | 17758 | 1761 |
SCN5A,MMD,TBC1D1,RASA2,CNTNAP2,PHLPP1,TRIB2,CD40,SPTLC2,SESN1,ATP10D,KDM4D,APLP2,PLCG1,RNF220,FAM46A,AGPAT2,CNTRL,PAIP2B,MMP17,GALNS,BCL6,TPST1,DTX4,SORL1,RAB20,PIK3C2B,ICOSLG |
| 1.356e-02 | -4.30 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 183 | 28 | 17758 | 1761 |
PLA2G4A,TTC39B,ALDH6A1,EPAS1,TACC1,GCLC,ATP8A1,S100A4,UBASH3B,PYROXD2,BLVRB,ABCG2,ARHGDIB,FAM198B,MGST2,ATP1B1,LMNA,PLS3,ARHGAP24,GRHL1,DTX4,FXYD5,NFKBIZ,AHCY,SPCS3,NAGA,CBX7,CYP1B1 |
| 1.356e-02 | -4.30 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 183 | 28 | 17758 | 1761 |
SLC35D2,CD55,ARHGEF3,PQLC3,OSTM1,HABP4,PIP4K2C,CACNA2D2,BTN3A1,TGOLN2,IL27RA,DENND2D,EPS8L2,FUCA1,PPP2R5A,JAK1,PASK,COL6A1,KLF3,FXYD5,CITED2,RCAN3,MYLIP,ALDH3A2,NCOA2,S100A6,CKAP4,KLF7 |
| 1.357e-02 | -4.30 | MODULE_433 | MSigDB lists | MODULE_433 | 60 | 12 | 17758 | 1761 |
MDK,PDGFA,NOV,IL15,CSF1,BMP7,BMP1,NRG2,NRG1,PDGFB,TNFSF9,S100A6 |
| 1.357e-02 | -4.30 | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | 60 | 12 | 17758 | 1761 |
CALM2,MRPS33,FOXM1,FXYD3,SPINT2,CALM1,RANBP1,CALM3,NUSAP1,UBE2C,CDK1,ARF4 |
| 1.357e-02 | -4.30 | chr7p15 | MSigDB lists | chr7p15 | 60 | 12 | 17758 | 1761 |
ITGB8,MACC1,ZNRF2,OSBPL3,HOXA9,CDCA7L,ANLN,SNX10,PRR15,AHR,SP4,HDAC9 |
| 1.358e-02 | -4.30 | VWA | pfam domains | PF00092 | 45 | 10 | 16629 | 1696 |
CACHD1,COL6A2,COL6A1,MATN2,PARP4,CACNA2D2,VWA1,COL7A1,ANTXR1,COL12A1 |
| 1.360e-02 | -4.30 | cellular response to decreased oxygen levels | biological process | GO:0036294 | 124 | 21 | 16441 | 1675 |
SIRT1,PINK1,NKX3-1,SLC2A4,CPEB4,AKT1,EPAS1,TP53,RGCC,SLC11A2,PDK3,CCNB1,LMNA,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,CPEB2,EGLN1 |
| 1.361e-02 | -4.30 | V$TCF1P_Q6 | MSigDB lists | V$TCF1P_Q6 | 249 | 36 | 17758 | 1761 |
BCAM,CPEB4,HOXB7,GGA1,COL18A1,NEO1,CDKN2C,SCNN1A,LMO4,BHLHE41,KLF3,DLG1,FXYD5,DUSP10,PIK3CD,SCN2A,RBMS2,SEPHS1,PLK1,TGIF1,MCTP1,SAT1,PIK3R1,RGAG1,PTGFRN,FOS,SP4,PITX2,ZNF367,SLC9A6,AMMECR1,FAM117A,EFNA5,ARF6,SEMA3A,JARID2 |
| 1.362e-02 | -4.30 | negative regulation of natural killer cell mediated immunity | biological process | GO:0002716 | 10 | 4 | 16441 | 1675 |
HLA-B,HLA-E,HLA-A,TAP1 |
| 1.362e-02 | -4.30 | meiotic spindle organization | biological process | GO:0000212 | 10 | 4 | 16441 | 1675 |
TUBG1,AURKA,ESPL1,ASPM |
| 1.362e-02 | -4.30 | metanephric tubule morphogenesis | biological process | GO:0072173 | 10 | 4 | 16441 | 1675 |
HES1,SOX8,LGR4,SOX9 |
| 1.362e-02 | -4.30 | regulation of Wnt signaling pathway, planar cell polarity pathway | biological process | GO:2000095 | 10 | 4 | 16441 | 1675 |
NPHP3,ANKRD6,DACT1,NKD1 |
| 1.362e-02 | -4.30 | fatty acid transmembrane transport | biological process | GO:1902001 | 10 | 4 | 16441 | 1675 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 1.362e-02 | -4.30 | negative regulation of natural killer cell mediated cytotoxicity | biological process | GO:0045953 | 10 | 4 | 16441 | 1675 |
HLA-B,HLA-E,HLA-A,TAP1 |
| 1.362e-02 | -4.30 | vagina development | biological process | GO:0060068 | 10 | 4 | 16441 | 1675 |
NCOA3,MERTK,AXL,BAX |
| 1.363e-02 | -4.30 | skin-back-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | skin-buttock-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | skin-chest-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-chest-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | groin | COSMIC cancer mutations | groin | 21 | 6 | 17775 | 1757 |
AKT1,IDH1,PTEN,GNA11,PIK3CA,TP53 |
| 1.363e-02 | -4.30 | skin-upper_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | skin-leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | skin-foot-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-foot-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.363e-02 | -4.30 | skin-shoulder-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.364e-02 | -4.29 | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | MSigDB lists | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | 464 | 61 | 17758 | 1761 |
PLA2G4A,PRKAA2,MTM1,ACACB,HSPG2,CPT2,HEXB,ASAH1,LPIN3,SDC1,PRKACA,LBR,CYP39A1,TEAD3,SGPL1,CDS1,CYP1A1,CTGF,GRHL1,PTEN,ARSG,BDH1,SLC44A1,FABP6,PIK3CA,AKR1B1,SLC44A2,ABCD1,PIK3CD,ACOX2,ACSL4,TECR,LGMN,PIKFYVE,FAR2,MED30,NCOA2,GM2A,MED22,FADS2,LPGAT1,PIK3R1,ELOVL3,PPARA,IDH1,SPTLC2,ARSK,NCOA3,PRKAG2,AGPAT2,CDK19,INPP4B,BMP1,SLC27A1,CTSA,PIK3C2B,GLA,PLD1,ARSB,ABCA1,ABCG1 |
| 1.365e-02 | -4.29 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | 175 | 27 | 17758 | 1761 |
HPS3,PPP1R2,ZNF395,LONRF3,POC1B,MPP1,SH3BGRL,SPATA13,PKP2,C2orf69,TGOLN2,TEX2,GRK6,SLC25A5,LEPR,SCARB2,NR1D2,CTSC,ELF5,KLF3,FAM63A,CLIP4,PHKA2,RASGEF1A,REEP4,AIFM3,SULF2 |
| 1.365e-02 | -4.29 | V$FOXJ2_01 | MSigDB lists | V$FOXJ2_01 | 175 | 27 | 17758 | 1761 |
CYP26B1,SSH3,RUNX2,CPEB4,CHCHD7,SLC39A8,RGAG1,NFIB,NEO1,SCML1,IER3,FOXP2,HSF2,KLF12,ARTN,COL13A1,BDH1,MITF,SLC44A1,KLF3,TWIST1,NRG1,BUB1,C1orf43,NCAM1,PKIA,RGMA |
| 1.365e-02 | -4.29 | GSE29618_BCELL_VS_MDC_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_UP | 175 | 27 | 17758 | 1761 |
SYPL1,SGCE,HECA,ZNF395,CKAP2,TSC22D3,EZR,ETS1,FAM46C,OPTN,RASGRP2,STK17A,ARHGAP24,SWAP70,ADD3,BANK1,PLCG2,ITPR1,RYK,VAT1,CLMN,TLE1,TSPAN13,PIK3C2B,PIKFYVE,RASGRP1,KLF7 |
| 1.368e-02 | -4.29 | Anoctamin | pfam domains | PF04547 | 10 | 4 | 16629 | 1696 |
ANO9,ANO4,ANO1,ANO6 |
| 1.368e-02 | -4.29 | DAGK_acc | pfam domains | PF00609 | 10 | 4 | 16629 | 1696 |
DGKH,DGKG,DGKQ,DGKE |
| 1.368e-02 | -4.29 | Amidohydro_1 | pfam domains | PF01979 | 10 | 4 | 16629 | 1696 |
DPYSL5,AMDHD1,DPYSL2,DPYSL3 |
| 1.369e-02 | -4.29 | Sertoli cell development | biological process | GO:0060009 | 15 | 5 | 16441 | 1675 |
SOX8,FNDC3A,SDC1,CST3,SOX9 |
| 1.369e-02 | -4.29 | protein targeting to lysosome | biological process | GO:0006622 | 15 | 5 | 16441 | 1675 |
SNX16,SORL1,ZFYVE16,SCARB2,GNPTAB |
| 1.369e-02 | -4.29 | metanephric nephron tubule development | biological process | GO:0072234 | 15 | 5 | 16441 | 1675 |
HES1,OSR1,SOX8,LGR4,SOX9 |
| 1.369e-02 | -4.29 | left/right axis specification | biological process | GO:0070986 | 15 | 5 | 16441 | 1675 |
EPB41L5,PITX2,SETDB2,CITED2,MNS1 |
| 1.369e-02 | -4.29 | positive regulation of endothelial cell apoptotic process | biological process | GO:2000353 | 15 | 5 | 16441 | 1675 |
COL18A1,GPER1,CD40,ANO6,RGCC |
| 1.369e-02 | -4.29 | unsaturated fatty acid metabolic process | biological process | GO:0033559 | 109 | 19 | 16441 | 1675 |
PLA2G4A,FADS2,FAM213B,ELOVL3,MGST2,RNPEP,CYP4F3,MAPKAPK2,CYP1A1,FAAH,CYP2S1,ABCD1,CYP2U1,LTA4H,PTGES,SYK,ABCC1,GPX4,CYP1B1 |
| 1.371e-02 | -4.29 | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | MSigDB lists | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | 151 | 24 | 17758 | 1761 |
ARHGAP11A,ZWINT,DLGAP5,HJURP,SPC25,CKAP2,NDC80,C5orf30,KIF23,NUSAP1,PIF1,CCNB1,ANLN,PSIP1,CASP4,TOP2A,SLCO4A1,DAZAP1,UBE2T,CENPE,SPCS3,NCAPG2,ESPL1,MELK |
| 1.371e-02 | -4.29 | NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | 151 | 24 | 17758 | 1761 |
ING1,NF2,IGFBP6,CDKN1C,S100A11,CNOT8,COL18A1,RUNX3,FTH1,TP53I11,PRKRA,ETS1,SESN1,CDKN2C,BTG3,PTEN,ACVRL1,SCG2,CGREF1,FABP6,KLF11,CDKN2D,TOB1,CD33 |
| 1.371e-02 | -4.29 | GAGCTGG,MIR-337 | MSigDB lists | GAGCTGG,MIR-337 | 151 | 24 | 17758 | 1761 |
MAP3K3,IER5L,SORT1,PACSIN2,ARAP3,THRA,DNAJB2,SEPT6,FAM133B,BCL2L1,GRK6,FOS,TYSND1,EFNB1,TEAD3,RAB15,KLF12,H1F0,MAP3K9,OVOL1,TWIST1,KLF11,GLCCI1,ACOT7 |
| 1.373e-02 | -4.29 | GTCTTCC,MIR-7 | MSigDB lists | GTCTTCC,MIR-7 | 159 | 25 | 17758 | 1761 |
CHSY3,ZNF395,ITCH,CNOT8,OXR1,PBX3,PLXNA1,HPCAL4,VPS26A,ARF4,IRS2,SLC4A4,KLF12,MAP3K9,NR4A3,FAM83D,ANKRD12,CNNM4,CRY2,ACSL4,PIK3CD,PIM1,PDE4D,SMYD5,CKAP4 |
| 1.373e-02 | -4.29 | TIEN_INTESTINE_PROBIOTICS_6HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_6HR_DN | 159 | 25 | 17758 | 1761 |
AMOTL2,PACSIN2,CENPA,MMD,ZNF395,RAPGEF2,HEXB,PLXNA1,NTAN1,SEPP1,EMP2,STEAP1,STX3,DNAJB9,PITX2,RAB15,PSMD1,PPP2R5A,CALD1,SGK1,ARMCX6,CPPED1,MELK,CKAP4,DOCK9 |
| 1.375e-02 | -4.29 | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | 27 | 7 | 17775 | 1757 |
GNAS,AKT1,IDH1,FGFR2,GNA11,RET,PIK3CA |
| 1.375e-02 | -4.29 | autonomic_ganglia-retroperitoneum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-retroperitoneum-neuroblastoma | 27 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,RET,PIK3R1,PIK3CA |
| 1.375e-02 | -4.29 | dedifferentiated | COSMIC cancer mutations | dedifferentiated | 27 | 7 | 17775 | 1757 |
GNAS,SS18,CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 1.375e-02 | -4.29 | schwannoma | COSMIC cancer mutations | schwannoma | 27 | 7 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,GNA11,RET,PIK3CA |
| 1.375e-02 | -4.29 | uDENN | pfam domains | PF03456 | 15 | 5 | 16629 | 1696 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.375e-02 | -4.29 | RasGAP | pfam domains | PF00616 | 15 | 5 | 16629 | 1696 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 1.379e-02 | -4.28 | KEGG_MAPK_SIGNALING_PATHWAY | MSigDB lists | KEGG_MAPK_SIGNALING_PATHWAY | 266 | 38 | 17758 | 1761 |
PLA2G4A,CASP3,RPS6KA1,RASA2,CACNA2D2,TP53,TGFBR1,MRAS,CACNB4,PDGFB,PRKACA,FGF19,MECOM,PDGFA,RPS6KA2,DUSP10,MAPK11,CACNA1D,RASGRP1,MAP3K3,RASGRF1,AKT1,NR4A1,RAPGEF2,DUSP4,ELK1,FOS,MAP3K6,MAPK8IP1,RASA1,RASGRP2,FAS,MAPKAPK2,FGFR2,ARRB1,MAP3K5,HSPB1,MAPK12 |
| 1.384e-02 | -4.28 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2342 | 262 | 17775 | 1757 |
HECA,PPP4R4,HSPG2,VANGL1,ATP8A1,RET,NRG2,CA8,GRM5,PQLC2,STIM1,RGS3,PRICKLE3,IL31RA,STEAP2,PIK3CA,SNX16,ARMCX6,TIAM1,TIPARP,ERAP2,SMARCA2,KIFC2,SNTB2,F12,COL12A1,AHRR,SLC25A4,PTER,GNPTAB,LRIG1,NOD2,TANC2,TRAF5,FRMD4A,SCOC,ITGA6,CALB2,TTYH3,FRY,SNX18,MEGF8,BDH1,DAPK1,CADPS2,ALPK1,PIKFYVE,MYLIP,DGKG,GPR161,KLK5,MICB,AMER1,ZNF503-AS2,TP53INP2,STK17A,PTPRF,NCOA3,AP1AR,ETS2,DCK,MATN2,RAET1L,ITPR1,FAM83D,FGD6,CABIN1,GDF11,DRP2,PER3,MAP3K5,SERPINB1,ADAMTS16,DOCK9,ST14,ACTR8,BROX,CCDC110,IQGAP1,PKP2,ZNF385B,APPBP2,MUC16,ST5,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,SCN3A,MYO5B,DOCK4,COG2,CAPN6,PLEKHO1,SYNE2,UTRN,PRKCQ,ALCAM,ATP10D,NIN,DDOST,INPP4B,PNPLA6,RGS14,ISOC1,ARHGEF3,NKX3-1,ATP9A,ESRP1,DNAH3,TMCC3,PDIA4,SNTA1,PTEN,CD9,ATP8B1,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,FMN1,GRIN1,CXorf57,PARP4,FURIN,NUCB1,PGM2L1,MELK,OCLN,TLL2,JARID2,ESYT2,UNKL,EXPH5,KIAA1462,EPHA4,ARFGEF1,MPP5,HDAC6,ERP29,SPTB,TRIM68,SIPA1L2,GRHL1,TSPAN6,MKRN3,ABCA2,POF1B,MYH14,TLN2,BTBD3,MYRIP,NEB,ZNF462,MCTP1,TRIM8,CELSR2,ITCH,KLK6,PTGFRN,IDH1,DPYSL3,PLEKHG6,HPSE,MADD,SP6,ADIPOR1,EPB41L4A,RRAGD,ARAP3,LGALS3,HJURP,ETV5,NCKAP1,SAMD9,AIM1L,TNS3,KIF13B,FRAS1,WNT3A,NCEH1,PLCB2,PCDH1,EIF2AK1,HEATR5A,RNF113A,NUBP1,MUM1L1,PRX,GNAS,ZDBF2,SHROOM2,LMO7,NCKAP5,FOXM1,TP53,CCDC68,SYTL2,SS18,ZNF687,SETDB2,ARTN,FRYL,LHX6,FABP6,GOT1,RPN2,TMEM64,PDIA6,SULF2,TMTC1,ACO1,ERBB2IP,DOCK5,FANCE,ARHGAP35,PTPRJ,RBL1,SECTM1,TLE1,SPTBN5,NDST3,BIN1,ANXA3,SORT1,MACC1,ARHGEF11,GTF3A,TRMT2B,SH2D4A,NRP2,SLC9A2,HMGXB4,HDAC9,TOP2A,CARD8,BMP7,LYPD6,GALNS,TOX2,KIAA0319,TRIM21,ABCD1,IQGAP3,ATP2B1,MYO5A,HMMR,PSMB4,NR4A1,COL7A1,MAML2,FNDC3A,TXNDC11,BANK1,UACA,ZMIZ1,L1CAM,GOLGB1,ARHGEF4 |
| 1.384e-02 | -4.28 | BIOCARTA_NOS1_PATHWAY | MSigDB lists | BIOCARTA_NOS1_PATHWAY | 21 | 6 | 17758 | 1761 |
CALM2,CALM3,GRIN2D,PRKAR2B,CALM1,GRIN1 |
| 1.384e-02 | -4.28 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | 21 | 6 | 17758 | 1761 |
GDF15,CYP1A1,PHLDA1,HSPB1,CSF1,EPS8 |
| 1.384e-02 | -4.28 | LANDIS_ERBB2_BREAST_TUMORS_65_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_65_UP | 21 | 6 | 17758 | 1761 |
CMAS,ITPR2,DAP,FHDC1,PDIA4,CD9 |
| 1.384e-02 | -4.28 | LANDEMAINE_LUNG_METASTASIS | MSigDB lists | LANDEMAINE_LUNG_METASTASIS | 21 | 6 | 17758 | 1761 |
CDH3,UGT8,ITGB8,PTEN,CALB2,GYLTL1B |
| 1.384e-02 | -4.28 | PID_S1P_S1P1_PATHWAY | MSigDB lists | PID_S1P_S1P1_PATHWAY | 21 | 6 | 17758 | 1761 |
PLCG1,RHOA,ITGAV,PLCB2,PDGFB,ABCC1 |
| 1.384e-02 | -4.28 | MAINTENANCE_OF_LOCALIZATION | MSigDB lists | MAINTENANCE_OF_LOCALIZATION | 21 | 6 | 17758 | 1761 |
PDIA3,GAA,FTH1,NFKBIE,ATP7B,MDFI |
| 1.384e-02 | -4.28 | BIOCARTA_IGF1_PATHWAY | MSigDB lists | BIOCARTA_IGF1_PATHWAY | 21 | 6 | 17758 | 1761 |
IGF1R,ELK1,FOS,RASA1,PIK3R1,PIK3CA |
| 1.384e-02 | -4.28 | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | 21 | 6 | 17758 | 1761 |
CTSA,RHOA,ARPC2,PRCP,HLA-A,CST3 |
| 1.388e-02 | -4.28 | D-myo-inositol-5-phosphate metabolism | BIOCYC pathways | HUMAN_PWY-6367 | 17 | 6 | 907 | 115 |
PLCG1,PLCH1,PLCB2,TMEM55B,PLCG2,PIP4K2C |
| 1.388e-02 | -4.28 | PDIA5 (protein disulfide isomerase family A, member 5) | protein interactions | 10954 | 25 | 7 | 16036 | 1726 |
NENF,MORF4L2,LGMN,PPP1R2,ANTXR1,TP53,MDFI |
| 1.389e-02 | -4.28 | regulation of generation of precursor metabolites and energy | biological process | GO:0043467 | 87 | 16 | 16441 | 1675 |
PRKAA2,PPIF,SORBS1,PINK1,RHOA,AKT1,PPARA,TP53,PRKACA,IER3,IRS2,ENPP1,PRKAG2,PASK,PIK3CA,PRKCDBP |
| 1.395e-02 | -4.27 | meninges | COSMIC cancer mutations | meninges | 528 | 68 | 17775 | 1757 |
NF2,HSPG2,RET,TP53,ERBB2,ITPR2,OSR2,HDAC6,CDKN2C,SS18,MUC16,RPS6KA2,TRANK1,WDR44,PIK3CA,IRF2,DAB2IP,ANO4,TIAM1,MGAT5,CYP1B1,MYO5B,AKT1,ACVR1C,CR2,IDH1,SLC25A5,IRS2,PLCH1,PPP2R5A,PTK7,ATP7B,TSPAN18,SIPA1L1,EPB41L4A,TANC2,NDST3,DEPDC1,GGA1,FRMD6,SOX9,AIP,GNS,FOXP2,DOPEY2,ADD3,MLPH,PTEN,PCYOX1,ERBB3,SYTL3,RIMS2,IGDCC4,SYPL1,PIK3R1,FBXO9,COL7A1,ATP8B3,BBS2,GNA11,ARHGAP24,MMP15,GNAS,PLOD2,FGFR2,SLC4A3,TMEM14A,EHD1 |
| 1.395e-02 | -4.27 | meningioma | COSMIC cancer mutations | meningioma | 528 | 68 | 17775 | 1757 |
NF2,HSPG2,RET,TP53,ERBB2,ITPR2,OSR2,HDAC6,CDKN2C,SS18,MUC16,RPS6KA2,TRANK1,WDR44,PIK3CA,IRF2,DAB2IP,ANO4,TIAM1,MGAT5,CYP1B1,MYO5B,AKT1,ACVR1C,CR2,IDH1,SLC25A5,IRS2,PLCH1,PPP2R5A,PTK7,ATP7B,TSPAN18,SIPA1L1,EPB41L4A,TANC2,NDST3,DEPDC1,GGA1,FRMD6,SOX9,AIP,GNS,FOXP2,DOPEY2,ADD3,MLPH,PTEN,PCYOX1,ERBB3,SYTL3,RIMS2,IGDCC4,SYPL1,PIK3R1,FBXO9,COL7A1,ATP8B3,BBS2,GNA11,ARHGAP24,MMP15,GNAS,PLOD2,FGFR2,SLC4A3,TMEM14A,EHD1 |
| 1.398e-02 | -4.27 | Mit_carrier | interpro domains | IPR002067 | 27 | 7 | 18293 | 1814 |
SLC25A48,SLC25A24,SLC25A4,SLC25A5,SLC25A43,SLC25A13,SLC25A36 |
| 1.398e-02 | -4.27 | BIOCARTA_EDG1_PATHWAY | MSigDB lists | BIOCARTA_EDG1_PATHWAY | 27 | 7 | 17758 | 1761 |
ASAH1,PDGFA,RHOA,ITGAV,AKT1,PIK3R1,PIK3CA |
| 1.398e-02 | -4.27 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | MSigDB lists | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | 27 | 7 | 17758 | 1761 |
IRS2,PIK3CD,JAK1,AKT1,JAK3,PIK3R1,PIK3CA |
| 1.398e-02 | -4.27 | PID_IL3_PATHWAY | MSigDB lists | PID_IL3_PATHWAY | 27 | 7 | 17758 | 1761 |
HDAC1,BCL2L1,PIM1,PRKACA,INPP5D,PIK3R1,PIK3CA |
| 1.398e-02 | -4.27 | KEGG_HISTIDINE_METABOLISM | MSigDB lists | KEGG_HISTIDINE_METABOLISM | 27 | 7 | 17758 | 1761 |
ALDH3B1,ALDH7A1,ALDH2,AMDHD1,ALDH3A2,ALDH1A3,HAL |
| 1.398e-02 | -4.27 | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | MSigDB lists | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | 27 | 7 | 17758 | 1761 |
MDK,IGFBP2,ADORA1,IGFBP6,FOS,RIMS2,IGSF3 |
| 1.398e-02 | -4.27 | ST_MYOCYTE_AD_PATHWAY | MSigDB lists | ST_MYOCYTE_AD_PATHWAY | 27 | 7 | 17758 | 1761 |
ASAH1,PITX2,ITPR2,ITPR3,AKT1,DAG1,ITPR1 |
| 1.403e-02 | -4.27 | CAMK2A (calcium/calmodulin-dependent protein kinase II alpha) | protein interactions | 815 | 69 | 14 | 16036 | 1726 |
DAPK2,PLCG1,AKT1,PTTG1,DLG1,GRIN1,CDCA8,CALM3,DLG3,ZMYM1,ITPKA,ETS1,CDK5R1,RAD23A |
| 1.408e-02 | -4.26 | organic hydroxy compound metabolic process | biological process | GO:1901615 | 487 | 65 | 16441 | 1675 |
PLA2G4A,EPAS1,CRYM,INPP5D,LPIN3,CYP39A1,CDS1,CALM2,APLP2,CYP1A1,IMPAD1,ALDH1A3,PLCG2,SLC44A1,FABP6,AKR1B1,TRPC1,GOT1,ACOX2,MINPP1,LGMN,CYP1B1,CYB5R2,CYP4F3,POR,PLCH1,PLCG1,DUOX1,ALDH3B1,PEX2,INPP4B,PNPLA6,SLC27A1,ITPKA,ABCA1,PRKAA2,CALM3,ISYNA1,DHRS3,SPR,LBR,PTEN,SORL1,SLC44A2,ATP8B1,ALDH7A1,PLCB2,ALDH3A2,MYO5A,NCOA2,SHMT1,ALDH2,CALM1,NPC2,PCTP,SPTLC2,LEPR,GPLD1,FECH,SLCO4A1,PRKAG2,DBI,NR4A2,APOL2,ABCG1 |
| 1.411e-02 | -4.26 | MODULE_40 | MSigDB lists | MODULE_40 | 82 | 15 | 17758 | 1761 |
FADS2,ALDH5A1,ALDH6A1,AGPAT2,CPT2,PLCG2,HAL,GOT1,ALDH7A1,MGST2,PLD1,ACOX2,OAT,IDH1,FAH |
| 1.411e-02 | -4.26 | MODULE_235 | MSigDB lists | MODULE_235 | 82 | 15 | 17758 | 1761 |
MMP15,GCLM,CA2,GCLC,GALNS,TPST1,ATP8B1,AHCY,GOT1,ICMT,OAT,ARSB,CA8,ALDH3A2,FAH |
| 1.414e-02 | -4.26 | hormone binding | molecular function | GO:0042562 | 66 | 13 | 16491 | 1673 |
THRB,SEC61B,ATP1A1,IDE,IGF1R,NR3C1,CRYM,THRA,ALDH1A3,PIK3R1,ADIPOR1,ECE1,GPER1 |
| 1.415e-02 | -4.26 | Adipogenesis | WikiPathways | WP236 | 131 | 24 | 4455 | 516 |
CYP26B1,SLC2A4,EPAS1,NR3C1,PPARA,GTF3A,LPIN3,CYP26A1,LMNA,SOCS3,FAS,IRS2,AGPAT2,GATA2,RBL1,IL6ST,BMP1,KLF5,TWIST1,HMGA1,AHR,LIFR,NCOA2,KLF7 |
| 1.415e-02 | -4.26 | positive regulation of neuron differentiation | biological process | GO:0045666 | 276 | 40 | 16441 | 1675 |
GRN,FOXO6,SERPINE2,RET,EPHA4,ETV5,CAMK1D,CRABP2,ITGA3,GATA2,MEGF8,BMP7,BCL6,TNFRSF12A,DAB2IP,PACSIN1,WNT3A,TIAM1,RIMS2,TLE6,TGIF1,RHOA,TIMP2,MMD,RAPGEF2,HMG20B,ARHGAP35,DPYSL3,GPRC5B,SEMA4D,BHLHB9,TMEM30A,LIMK1,PTK7,NRG1,EFNA5,ITPKA,ARSB,L1CAM,COBL |
| 1.416e-02 | -4.26 | SYSTEM_DEVELOPMENT | MSigDB lists | SYSTEM_DEVELOPMENT | 842 | 103 | 17758 | 1761 |
GAA,MTM1,UGT8,PAPSS2,NF2,RET,ERBB2,COL18A1,IL18,MRAS,DNER,CTGF,ARTN,SHC3,DPYSL2,LMO4,LHX6,PAPSS1,IL31RA,TWIST1,EPHB4,DVL2,SEMA3B,SGCE,MBP,UTRN,HTATIP2,ZBTB7B,COL12A1,DPYSL3,MDK,ALDH5A1,LIMK1,WFS1,SECTM1,BMP1,TLE1,EFNA5,TMOD2,SERPINI1,NRGN,NR2C2,MAPK12,FGD1,RUNX2,CIT,PBX3,AES,NCKAP1,CRABP2,GSTP1,ETS1,FGF19,HPCAL4,NRP2,ELF3,HDAC9,FOXP2,ADORA1,PTEN,TFAP2A,BAX,CD9,OSTF1,CITED2,SGCB,ETV7,MYLIP,SPRY2,SYK,ALDH3A2,SOCS5,FARP2,DPYSL5,HES1,PDGFC,KLK5,PCDH1,GYLTL1B,STMN3,COL7A1,NPHP3,CDK5R1,RASA1,PITX2,ETS2,TIMM8A,SCG2,COL13A1,ACVRL1,ITGA7,CSF1,ERAP1,ALPK3,EGFL7,KLK7,HOXB13,GDF11,DRP2,SOX8,SHROOM2,L1CAM,JARID2 |
| 1.418e-02 | -4.26 | actin filament bundle organization | biological process | GO:0061572 | 52 | 11 | 16441 | 1675 |
SORBS1,RHOA,SWAP70,ADD1,EPS8,ARRB1,EZR,ESPN,FAM101B,SHROOM2,DPYSL3 |
| 1.418e-02 | -4.26 | cGMP-PKG signaling pathway | KEGG pathways | ko04022 | 167 | 28 | 6908 | 758 |
MYL9,PPIF,RHOA,AKT1,CALM1,PIK3R1,PDE5A,CALM3,ATP1B1,ITPR2,ITPR3,SLC25A5,GNA11,EDNRA,IRS2,CALM2,ATP1A1,KCNMB4,ADORA1,SLC25A4,ITPR1,PIK3CA,PRKG1,ATP1B3,PIK3CD,CACNA1D,PLCB2,ATP2B1 |
| 1.418e-02 | -4.26 | cGMP-PKG signaling pathway | KEGG pathways | hsa04022 | 167 | 28 | 6908 | 758 |
MYL9,PPIF,RHOA,AKT1,CALM1,PIK3R1,PDE5A,CALM3,ATP1B1,ITPR2,ITPR3,SLC25A5,GNA11,EDNRA,IRS2,CALM2,ATP1A1,KCNMB4,ADORA1,SLC25A4,ITPR1,PIK3CA,PRKG1,ATP1B3,PIK3CD,CACNA1D,PLCB2,ATP2B1 |
| 1.419e-02 | -4.26 | RICKMAN_HEAD_AND_NECK_CANCER_C | MSigDB lists | RICKMAN_HEAD_AND_NECK_CANCER_C | 97 | 17 | 17758 | 1761 |
KLK10,KLK5,AMFR,CALB2,RGS20,CDA,KLK6,AMDHD1,POPDC3,RNF128,PAQR5,FLRT3,HOXA9,REEP1,KLK7,NRG1,ERAP2 |
| 1.419e-02 | -4.26 | FN3 | prosite domains | PS50853 | 191 | 30 | 11866 | 1235 |
PTPRU,EPHA4,VWA1,COL7A1,IL27RA,IL13RA1,EPHA1,FNDC3A,MERTK,LEPR,COL12A1,NEO1,EPHA10,TRIM9,PTPRF,PTPRJ,IGSF9,IGF1R,AXL,IL6ST,VASN,FLRT3,IL31RA,ANKFN1,SORL1,EPHB4,NCAM1,L1CAM,LIFR,IGDCC4 |
| 1.420e-02 | -4.25 | MODULE_459 | MSigDB lists | MODULE_459 | 395 | 53 | 17758 | 1761 |
LMTK3,FAM169A,CDH22,AASS,MRPS15,TP53,SLC25A27,C6orf106,CTSZ,ISYNA1,NANS,IL18R1,CMTM6,C9orf69,CYP1A1,RNF220,CDK16,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,CNOT6L,FAIM,CITED2,ATG4D,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,AMZ2,FUCA1,NEIL1,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,PKIA,RRAGD |
| 1.425e-02 | -4.25 | calcium channel regulator activity | molecular function | GO:0005246 | 39 | 9 | 16491 | 1673 |
CCDC109B,STIM1,ITPR1,SGK3,PRKG1,CACNA2D2,SGK1,TSPAN13,HPCAL4 |
| 1.427e-02 | -4.25 | peptidyl-asparagine modification | biological process | GO:0018196 | 179 | 28 | 16441 | 1675 |
GFPT1,SEC23A,CMAS,GNE,MGAT4B,PDIA3,CTSZ,COL7A1,NANS,B4GALT4,MCFD2,FUCA1,MAN2A2,UAP1,DDOST,SERPINA1,CTSC,DOLPP1,MGAT4A,ALG13,FUT8,UBE2J1,CTSA,RPN2,LMAN1,ST3GAL1,MGAT5,PPP6R1 |
| 1.427e-02 | -4.25 | mitotic spindle | cellular component | GO:0072686 | 53 | 11 | 17570 | 1756 |
ASPM,AGBL5,FAM83D,AURKA,KIF23,NUSAP1,CTTN,CENPE,GEM,ESPL1,CDK1 |
| 1.431e-02 | -4.25 | negative regulation of immune response | biological process | GO:0050777 | 117 | 20 | 16441 | 1675 |
CD55,LGALS3,PSMB4,NLRX1,INPP5D,HLA-E,TAP1,IL27RA,ABR,HLA-A,HLA-B,NMI,NOD2,NLRC5,BCL6,DUSP10,C10orf54,NDFIP1,JAK3,SOCS5 |
| 1.435e-02 | -4.24 | mast cell granule | cellular component | GO:0042629 | 21 | 6 | 17570 | 1756 |
AKR1B1,PIK3CD,GATA2,S100A13,RASGRP1,NR4A3 |
| 1.438e-02 | -4.24 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | 192 | 29 | 17758 | 1761 |
PPIF,PCGF5,CMAS,MBP,CPT2,DAP,SEPT6,PTTG1,ARL4C,ARFRP1,ISYNA1,BLVRA,RAD17,ETS1,REPS1,CMTM7,RABGGTA,ATP6V0B,SWAP70,STK38,PHTF1,DBI,ABCA2,FAM117A,CTSA,PIK3CD,PDIA6,TIAM1,CDKN2D |
| 1.438e-02 | -4.24 | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | 192 | 29 | 17758 | 1761 |
LAMP2,PMPCB,GOLIM4,LGALS3,GUSB,FRMD6,PDIA5,KCTD12,MRPS36,ERP29,DDR1,TNFSF9,PSMA4,DPYSL3,FAM111A,ONECUT1,HSF2,MDM1,TIMM8A,H1F0,NPNT,RPL39,FOSB,NR4A2,ERBB3,IQGAP3,SNX10,LIFR,MAPK12 |
| 1.438e-02 | -4.24 | GSE3982_DC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_UP | 192 | 29 | 17758 | 1761 |
FADS2,ARHGEF3,CPT2,GALNT12,GTF3A,VASH1,CENPN,HOXB2,PPP2R3A,FUCA1,RCN1,SS18,CA2,DPYSL2,PTER,KIF13B,OSBPL3,P4HA2,CST3,OTUB2,AKR1B1,TUBG1,ECI2,RAB20,TACSTD2,CTTN,LMAN1,ACOT7,FAM69A |
| 1.438e-02 | -4.24 | GSE27786_NKCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_UP | 192 | 29 | 17758 | 1761 |
HES1,TMEM68,PLEKHA6,HPS3,CITED4,NFKBIE,GUSB,PSME2,SH3BGRL,PIK3R1,SAT1,C6orf106,PRKCQ,POMGNT1,OAT,PDGFB,TMCC3,GABARAPL1,ZDHHC21,SESN3,IL6ST,GTF2F2,SLC44A2,ARL4D,JAK3,SPRY2,DDX59,DIS3L,PARP9 |
| 1.438e-02 | -4.24 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | 192 | 29 | 17758 | 1761 |
TGIF1,SCN5A,SLC25A24,CRYM,PSME2,ARHGDIB,CD40,IDH1,FOS,OPTN,FAS,CARD8,SP100,GPRC5B,DHRS2,KIF14,NAT1,RPL39,SRR,TRIM21,DIXDC1,IFIT1,ACOX2,GLA,MYBL1,RAP1GAP,RASGRP1,CD33,CKS2 |
| 1.438e-02 | -4.24 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 192 | 29 | 17758 | 1761 |
CASP3,NUDT6,GAA,LASP1,SEC61B,NDUFA4,SCRIB,NPC2,KCTD2,IL18R1,WWP2,EPCAM,AP1M2,C19orf66,H1F0,ITGA7,ELF5,FAM13B,DBI,DRAM1,POF1B,TACSTD2,MRPS28,ACOX2,PTPRE,CKAP4,ACOT7,PARP9,CYP1B1 |
| 1.438e-02 | -4.24 | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | 192 | 29 | 17758 | 1761 |
CCNI,GOLIM4,AVPI1,MMD,NF2,LPGAT1,CUL4B,CYS1,MGAT4B,TP53,TESK2,TGFBR1,GLO1,ARHGDIB,PRKACA,ANKRD10,SLC25A4,ELMO2,STK38,PELI2,BDH1,N4BP3,TBCD,COL6A1,TSPAN13,ERBB3,MYL12B,CRTAP,GPX4 |
| 1.438e-02 | -4.24 | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | 192 | 29 | 17758 | 1761 |
SUSD3,MYO5B,EPB41L5,KLK10,RUNX2,IGFBP6,LGALS3,PPM1J,HEBP1,SDC4,RUNX3,FAM198B,LOXL2,DOCK5,STX3,BSDC1,FRMD4B,FOXD2,NUCB1,ARTN,CSF1,DRAM1,SYT13,ECE1,TIPARP,C12orf75,S100A6,DEF6,GCNT1 |
| 1.438e-02 | -4.24 | GSE17721_CTRL_VS_POLYIC_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDM_DN | 192 | 29 | 17758 | 1761 |
GCA,MFI2,RIPK2,IQGAP1,CYS1,SYNE2,PRICKLE1,NDRG2,DNAJB11,RAB38,SPTLC2,TNFSF9,PSMA4,ARF4,APPBP2,CD83,PGF,IGF1R,PIK3AP1,PVRL2,GDE1,WFS1,HDAC1,MAPK11,HMGA1,PIM1,CTTN,FZD5,PPP2R2D |
| 1.438e-02 | -4.24 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | 192 | 29 | 17758 | 1761 |
SYPL1,LCA5,PPM1J,AK7,ITGA6,SELL,TGFBR1,TP53I11,DUSP4,PHLPP1,NUCB2,FAM81A,SESN1,TMPRSS4,DAG1,IL17RB,E2F7,NCOA3,FAM46A,RANBP1,KLC3,NR4A3,FAM83D,TMEM64,NEB,GM2A,S100A6,MELK,RRAGD |
| 1.438e-02 | -4.24 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | 192 | 29 | 17758 | 1761 |
RMND5A,SUN2,DYNLRB1,ADD1,DLGAP5,KIF20A,PEX6,DAP,SEPT6,PIK3R1,SPATA13,CDCA8,TCF7,ARHGDIB,MGST2,KIF11,PLS3,EPCAM,NUCB1,PHTF1,CD9,FXYD5,PRKCDBP,CDKN1B,CTSA,RNF26,NRGN,CTDSP2,KDELR1 |
| 1.444e-02 | -4.24 | condensed chromosome, centromeric region | cellular component | GO:0000779 | 104 | 18 | 17570 | 1756 |
PLK1,REC8,ZWINT,CENPA,SPC25,HJURP,SEPT6,NDC80,NUF2,CCNB1,CENPN,DCTN6,NEK2,AURKA,BUB1,CENPE,NDE1,NUP85 |
| 1.450e-02 | -4.23 | cellular polysaccharide metabolic process | biological process | GO:0044264 | 73 | 14 | 16441 | 1675 |
CALM2,PGM1,GAA,B3GNT2,PRKAG2,PPP1R2,UGP2,AKT1,IL6ST,CALM1,CALM3,PGM2L1,NANS,PHKA2 |
| 1.452e-02 | -4.23 | PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) | protein interactions | 5156 | 37 | 9 | 16036 | 1726 |
PDGFA,PLCG1,PDGFC,JAK1,PTEN,PIK3R1,ITGAV,PDGFB,ULBP2 |
| 1.452e-02 | -4.23 | MAPK12 (mitogen-activated protein kinase 12) | protein interactions | 6300 | 37 | 9 | 16036 | 1726 |
SNTA1,MBP,RGS3,DLG1,ERBB2IP,SNTB1,DLG3,PKN1,MAPK12 |
| 1.452e-02 | -4.23 | TPT1 (tumor protein, translationally-controlled 1) | protein interactions | 7178 | 37 | 9 | 16036 | 1726 |
PLK1,ATP1A1,NKX3-1,CALM1,TP53,SAMD9,NOTCH3,BCL2L1,HSPB1 |
| 1.453e-02 | -4.23 | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | 184 | 28 | 17758 | 1761 |
GFPT1,CD55,ALDH2,LGALS3,ERBB2IP,RAB6A,RAD17,PHLPP1,IDH1,CRISPLD2,CYB5A,SGPL1,WWP2,MAN2A2,WEE1,HSF2,PPP2R5A,SERPINA1,HPSE,RAB11FIP2,PLK2,DACT1,NEK2,RFX5,LRIF1,SERPINB1,IFIH1,AHR |
| 1.454e-02 | -4.23 | ACOABINDINGP | prints domains | PR00689 | 6 | 3 | 4759 | 462 |
ACBD5,ECI2,DBI |
| 1.454e-02 | -4.23 | MAP2K3 (mitogen-activated protein kinase kinase 3) | protein interactions | 5606 | 31 | 8 | 16036 | 1726 |
MAP3K3,ARRB1,ELK1,PKN1,MAP3K5,PLCB2,MAPK8IP1,MAPK12 |
| 1.455e-02 | -4.23 | spindle midzone | cellular component | GO:0051233 | 27 | 7 | 17570 | 1756 |
PLK1,AURKA,CENPE,CTTN,GEM,KIF14,CDCA8 |
| 1.456e-02 | -4.23 | LGALS8 (lectin, galactoside-binding, soluble, 8) | protein interactions | 3964 | 104 | 19 | 16036 | 1726 |
ENPP4,CLCN3,MRC2,CD63,OSTM1,ITGA6,ANO6,PTGFRN,ALCAM,BARD1,DAG1,TMEM63A,SCARB2,PTPRJ,ITGA3,SLC9A6,ITGA7,SORL1,SLC12A2 |
| 1.461e-02 | -4.23 | regulation of cell junction assembly | biological process | GO:1901888 | 66 | 13 | 16441 | 1675 |
EPB41L5,PTPRJ,ACVRL1,PTEN,FMN1,CORO1C,RAPGEF2,SDC4,PKP2,EFNA5,FZD5,PRKACA,COL16A1 |
| 1.461e-02 | -4.23 | mitotic spindle organization | biological process | GO:0007052 | 66 | 13 | 16441 | 1675 |
DCTN6,SUN2,RHOA,SPC25,PLK2,NDC80,MYBL2,NEK2,AURKA,KIF23,WDR62,STIL,KIF11 |
| 1.462e-02 | -4.23 | chr10q21 | MSigDB lists | chr10q21 | 40 | 9 | 17758 | 1761 |
SIRT1,ZWINT,ADAMTS14,EIF4EBP2,RTKN2,ZNF365,CDK1,VPS26A,SGPL1 |
| 1.462e-02 | -4.23 | ST_JNK_MAPK_PATHWAY | MSigDB lists | ST_JNK_MAPK_PATHWAY | 40 | 9 | 17758 | 1761 |
MAP3K3,AKT1,TP53,MAP3K9,DUSP10,DUSP4,MAP3K5,GAB1,NR2C2 |
| 1.462e-02 | -4.23 | FUJII_YBX1_TARGETS_UP | MSigDB lists | FUJII_YBX1_TARGETS_UP | 40 | 9 | 17758 | 1761 |
NLRC5,POF1B,DIAPH2,PRICKLE1,KLF11,TRIB2,SEPP1,S100A6,FAS |
| 1.462e-02 | -4.23 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | 40 | 9 | 17758 | 1761 |
GCLM,TRIM2,CYP4F11,GCLC,SLC39A8,AIM1,ABCB1,BTN3A2,KLF9 |
| 1.462e-02 | -4.23 | spleen development | biological process | GO:0048536 | 39 | 9 | 16441 | 1675 |
PITX2,ONECUT1,RC3H2,PPP2R3C,CITED2,PKN1,CACNB4,JARID2,FAS |
| 1.462e-02 | -4.23 | negative regulation of transcription factor import into nucleus | biological process | GO:0042992 | 39 | 9 | 16441 | 1675 |
NOV,NFKBIE,THRA,BMP7,NFKBIA,LITAF,RAB23,PSMD10,MDFI |
| 1.462e-02 | -4.23 | anatomical structure maturation | biological process | GO:0071695 | 39 | 9 | 16441 | 1675 |
RHOA,FAT4,ACVRL1,SEMA4D,ANO6,RET,GRIN1,DAG1,CDK5R1 |
| 1.463e-02 | -4.22 | regulation of proteolysis | biological process | GO:0030162 | 759 | 96 | 16441 | 1675 |
CASP3,DLGAP5,RPS6KA1,CAST,PSME2,PTTG1,RET,TP53,PSME1,CCNB1,HDAC6,PRKACA,BCAP31,RAD23A,APLP2,PSMD1,RPS6KA2,CTGF,CDKN1B,DAB2IP,EGLN3,CDKN2D,F2R,PLK1,SIRT1,CD55,TIMP2,AKT1,ACVR1C,ITCH,PBK,USP18,CASP9,CDC20,SLC11A2,F12,RNF19B,SNX12,CDK1,POR,IDE,NGFRAP1,PLK2,SERPINB6,SERPINI1,MAPK12,PINK1,NKX3-1,PCOLCE,SERPINE2,DAP,DNAJB2,RAB23,PSMD10,TRIB2,FBLN1,CD109,TFAP4,CARD8,CYR61,CTSC,PTEN,CST3,BAX,DAPK1,TRIM21,SORL1,BUB1,WNT3A,SOCS5,RHOA,PSMB4,MFI2,PLAUR,GCLC,NUB1,FURIN,PRICKLE1,COL7A1,PSMA4,FAS,GPLD1,TIMP3,SERPINA1,SPINT2,AURKA,ARRB1,GPER1,CENPE,MAP3K5,SERPINB1,UBE2C,ESPL1,IFI6,XDH,USP43 |
| 1.465e-02 | -4.22 | transcription factor binding | molecular function | GO:0008134 | 516 | 68 | 16491 | 1673 |
GAS2L1,ADD1,EPAS1,THRA,TSC22D3,HDAC11,TP53,CCND1,SP100,LMO4,FOSB,TWIST1,MED30,SIRT1,DRAP1,ICMT,GTF2A2,OPTN,GABARAPL1,RBL1,GNPTAB,PRDM5,HDAC1,TLE1,TTC8,RUNX2,NKX3-1,SOX9,DGKQ,PSMD10,HMGN3,HES2,TRIB2,ETS1,PSIP1,AIP,TEAD3,WWP2,HDAC9,TAF1B,GATA2,BHLHE41,TOX2,TFAP2A,MDFIC,PIM1,LRIF1,NCOA2,MDFI,HES1,PIK3R1,PPARA,PRICKLE1,BBS2,FOS,PITX2,NCOA3,SETD3,NFKBIA,NR4A3,ARRB1,NR4A2,HMGA1,SOX8,USF2,AHR,RARG,TMEM173 |
| 1.466e-02 | -4.22 | CELL_SURFACE | MSigDB lists | CELL_SURFACE | 75 | 14 | 17758 | 1761 |
BCAM,SLC2A4,ACVRL1,FGFR2,ALPP,PLAUR,RC3H2,PGRMC1,ABCB1,ANXA9,EPHB4,HSPB1,SULF2,M6PR |
| 1.466e-02 | -4.22 | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | MSigDB lists | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | 75 | 14 | 17758 | 1761 |
NOV,PLSCR1,CDH1,ZFP36,S100A4,MITF,LITAF,IL18,MERTK,FOS,PHLDA1,STX3,SIRPA,EHD1 |
| 1.466e-02 | -4.22 | LIN_APC_TARGETS | MSigDB lists | LIN_APC_TARGETS | 75 | 14 | 17758 | 1761 |
CCND1,CD99,SCN5A,S100A4,CTDSPL,HMG20B,AES,ETS1,L1CAM,BCAP31,SYK,CAPN1,LMNA,ABCC1 |
| 1.466e-02 | -4.22 | THIOL_PROTEASE_ASN | prosite domains | PS00640 | 10 | 4 | 11866 | 1235 |
CTSL,CTSZ,CTSC,CTSV |
| 1.469e-02 | -4.22 | regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001242 | 148 | 24 | 16441 | 1675 |
PPIF,SIRT1,PINK1,NKX3-1,BMF,AKT1,FIGNL1,PLAUR,TP53,BCL2L1,PRKRA,ERP29,BCAP31,MAPK8IP1,G2E3,DAPK2,DNM1L,WFS1,BAX,PLEKHF1,TMBIM6,BUB1,CDKN2D,HSPB1 |
| 1.470e-02 | -4.22 | regulation of leukocyte activation | biological process | GO:0002694 | 428 | 58 | 16441 | 1675 |
LAMP1,CASP3,LGALS3,IL15,INPP5D,HLA-E,ERBB2,IL27RA,IL18,CD274,SLC7A2,PKN1,MERTK,TNFSF9,EFNB1,HLA-A,IL6ST,IL31RA,BCL6,PIK3CA,DLG1,IGFBP2,C10orf54,SLC39A10,WNT3A,PTPRE,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,PLSCR1,RIPK2,AKT1,ITCH,PIK3R1,PDE5A,PRKCQ,YES1,CD40,ABR,FAS,SOX13,CD83,IRS2,BANK1,PVRL2,AXL,NR4A3,NOD2,PPP2R3C,GPER1,ICOSLG,NDFIP1,JAK3,F2RL1,AHR |
| 1.471e-02 | -4.22 | IRS1 (insulin receptor substrate 1) | protein interactions | 3667 | 90 | 17 | 16036 | 1726 |
SIRT1,AKT1,PTPRU,PIK3R1,ERBB2,PRKCQ,BCL2L1,SOCS3,PTPRF,IRS2,JAK1,CDH1,IGF1R,PLCG2,PIK3CA,JAK3,DVL2 |
| 1.471e-02 | -4.22 | human chr14q22.1 | chromosome location | human chr14q22.1 | 21 | 5 | 26250 | 1887 |
TRIM9,ATL1,FRMD6,ERO1A,NIN |
| 1.472e-02 | -4.22 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 268 | 38 | 17775 | 1757 |
CPEB4,TP53,SAMD9,ITPR2,PHLPP1,ETS1,TNFSF9,SLC9A2,CCND1,BTG3,MUC16,PTEN,GATA2,FABP6,PLCG2,BCL6,SGK1,CD70,NOTCH3,PIM1,SYK,PDGFC,SMARCA2,RHOA,CELSR2,TACC1,NR3C1,BCL9,PIK3R1,UBE2A,IDH1,FAS,GNAS,PLCG1,JAK1,TMEM30A,NFKBIA,JAK3 |
| 1.473e-02 | -4.22 | CUB | smart domains | SM00042 | 49 | 11 | 9131 | 997 |
PDGFC,PCOLCE,ST14,MEGF8,NETO2,BMP1,ATRNL1,KREMEN1,NRP2,DCBLD1,TLL2 |
| 1.474e-02 | -4.22 | SESTO_RESPONSE_TO_UV_C0 | MSigDB lists | SESTO_RESPONSE_TO_UV_C0 | 105 | 18 | 17758 | 1761 |
PPIF,PRSS8,TAP1,NDUFA4,GDF15,RNF113A,MCFD2,GTF2A2,PSMA4,M6PR,HNRNPH2,ZFP36,NFKBIA,PGRMC1,TACSTD2,ERBB3,CITED2,TRAM1 |
| 1.474e-02 | -4.22 | AAACCAC,MIR-140 | MSigDB lists | AAACCAC,MIR-140 | 105 | 18 | 17758 | 1761 |
PHF20L1,MMD,NR3C1,OSTM1,UBASH3B,BCL9,CIT,SLC25A13,STRADB,YES1,TP53INP2,C3orf58,PITX2,REEP1,SRR,RTKN2,PRIMA1,EHD1 |
| 1.475e-02 | -4.22 | human chr2q22-q23 | chromosome location | human chr2q22-q23 | 3 | 2 | 26250 | 1887 |
NR4A2,CACNB4 |
| 1.475e-02 | -4.22 | human chr2q23.2 | chromosome location | human chr2q23.2 | 3 | 2 | 26250 | 1887 |
LYPD6,MMADHC |
| 1.475e-02 | -4.22 | human chr3q28-q29 | chromosome location | human chr3q28-q29 | 3 | 2 | 26250 | 1887 |
HES1,MFI2 |
| 1.479e-02 | -4.21 | GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN | 160 | 25 | 17758 | 1761 |
IER5L,ATL1,NQO1,PYROXD2,LPGAT1,FRMD6,RAB23,NDRG2,F12,S100A2,TMCC3,FRY,FAM46A,PIK3AP1,METTL7A,TWSG1,PLCG2,RRBP1,RUNDC3B,ARRB1,LIMCH1,EIF4EBP2,MTMR11,NCAM1,ACOT7 |
| 1.484e-02 | -4.21 | microtubule associated complex | cellular component | GO:0005875 | 143 | 23 | 17570 | 1756 |
DYNLRB1,KIFC2,KIF20A,CDCA8,KIF23,KIF1C,KIF13A,HDAC6,DNAH3,KIF11,RANBP9,APPBP2,KIF5B,DCTN6,MAP2,KIF13B,KIF14,KLC3,AURKA,SPTBN5,CENPE,NDE1,CLIP2 |
| 1.486e-02 | -4.21 | human chr9q22 | chromosome location | human chr9q22 | 14 | 4 | 26250 | 1887 |
TGFBR1,SYK,CKS2,NR4A3 |
| 1.488e-02 | -4.21 | iron ion homeostasis | biological process | GO:0055072 | 95 | 17 | 16441 | 1675 |
MFI2,EPAS1,ABCG2,ACO1,TTC7A,EIF2AK1,FTH1,SLC11A2,NUBP1,SFXN5,STEAP1,NEO1,FECH,ATP6V0B,STEAP2,NDFIP1,CYBRD1 |
| 1.492e-02 | -4.21 | transmembrane transport | biological process | GO:0055085 | 1154 | 140 | 16441 | 1675 |
ACACB,SLC35D2,ADD1,CPT2,TSC22D3,SLC25A13,ATP8A1,TAP1,CACNA2D2,ITPR2,CACNB4,SLC20A1,SLC8B1,TMC1,SLC9A7,NCS1,ABCD4,PQLC2,SLC44A1,KCNS3,ABCA2,TRPC1,TMEM37,SLC39A10,ANO4,ORAI2,KCNIP3,SLC35C1,PRKAR2B,SLC25A5,SPNS3,KCNMB4,SLC25A4,KCNK1,ATP7B,PIEZO1,PRKAA2,LASP1,SCN5A,PEX6,FXYD3,SLC22A31,ABCG2,NDUFA4,SLC36A4,SLC1A3,COX6C,TTYH3,ANO1,ATP5H,KCNN4,SLC16A6,PCYOX1,FXYD5,CACNA1D,PANX2,SLC12A2,NUP85,ABCC1,KCNJ12,SLC37A1,ANO6,SFXN5,STEAP1,MFSD7,CYB5A,GNAS,SLCO4A1,GABRD,SLC6A6,PRKAG2,SLC4A4,MFSD2A,TMEM30A,SLC2A6,ITPR1,SLC4A3,ATP1B3,SHROOM2,NUP58,NIPA1,MFSD3,SLC25A24,SLC2A4,CCDC109B,RALBP1,ATP2C2,FTH1,SLC7A2,PRKACA,ATP6V0B,SLC25A48,SCNN1A,CNNM4,SCN2A,SCN3A,MYO5B,CLCN3,OSTM1,SLC39A8,SLC11A2,ATP1B1,ITPR3,ATP10D,ATP13A2,ATP1A1,SLC9A6,PEX2,SLC27A1,ABCA1,DENND5B,MFSD14B,GABRG2,CYB561,ANO9,SLC25A43,SLC9A2,SLC25A36,ADD3,SLC27A6,SGK3,BAX,SLC44A2,ATP8B1,SGK1,ABCD1,WWP1,SLC16A5,TPCN1,ATP2B1,S100A6,MRS2,GRIN1,RAB11FIP2,ABCB1,GRIN2D,ITGAV,ARHGEF9,CYBRD1,ABCG1 |
| 1.492e-02 | -4.20 | RAS_GTPASE_ACTIV_2 | prosite domains | PS50018 | 15 | 5 | 11866 | 1235 |
DAB2IP,IQGAP3,RASA2,IQGAP1,RASA1 |
| 1.492e-02 | -4.20 | OTU | prosite domains | PS50802 | 15 | 5 | 11866 | 1235 |
OTUB2,YOD1,OTUD1,ZRANB1,ALG13 |
| 1.492e-02 | -4.20 | response to corticosteroid | biological process | GO:0031960 | 156 | 25 | 16441 | 1675 |
ANXA3,CASP3,RHOA,NR3C1,PTPRU,CALM1,CASP9,CALM3,FOS,SDC1,FAS,SOCS3,FECH,TFAP4,CCND1,MDK,CALM2,CTGF,CTSV,FOSB,BAX,IGFBP2,GOT1,KLF9,GPER1 |
| 1.494e-02 | -4.20 | PURINE_NUCLEOTIDE_BINDING | MSigDB lists | PURINE_NUCLEOTIDE_BINDING | 209 | 31 | 17758 | 1761 |
MX1,PINK1,PEX6,GCLC,SEPT6,TP53,ABCG2,TGFBR1,PIF1,AIFM2,MAP3K6,STK17B,DGKE,RHEB,ABCD4,STK17A,DAPK2,RND3,ACVRL1,STK38,ATP7B,ABCB1,DAPK1,ABCA2,PIM1,GEM,MAP3K5,ARF6,ABCC1,ABCG1,SEPHS1 |
| 1.495e-02 | -4.20 | FN3_dom | interpro domains | IPR003961 | 209 | 31 | 18293 | 1814 |
PTPRU,EPHA4,VWA1,IL27RA,COL7A1,IL13RA1,EPHA1,FNDC3A,MERTK,LEPR,COL12A1,NEO1,EPHA10,PTPRF,TRIM9,PTPRJ,IGSF9,IGF1R,VASN,FLRT3,AXL,IL6ST,ANKFN1,IL31RA,KIAA0319,SORL1,EPHB4,NCAM1,L1CAM,LIFR,IGDCC4 |
| 1.501e-02 | -4.20 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 369 | 51 | 16441 | 1675 |
PINK1,BMF,NF2,SOX9,SDC4,TP53,TGFBR1,NCKAP1,HDAC6,SDC1,MNS1,SRPX2,EPS8L2,ADGRB2,CTGF,BMP7,FLRT3,MITF,GTF2F2,DLG1,PLK4,BAX,CDKN1B,ESPN,TWIST1,CTTN,CNOT6L,EPB41L5,RHOA,FMN1,RGCC,PIP4K2C,PRKCQ,EPHA1,LDB2,DAG1,FAS,DPYSL3,SWAP70,IDE,PTPRJ,BHLHB9,LIMK1,EFNA5,PIEZO1,ARPC2,ARF6,F2RL1,AHR,COL16A1,COBL |
| 1.505e-02 | -4.20 | V$LFA1_Q6 | MSigDB lists | V$LFA1_Q6 | 234 | 34 | 17758 | 1761 |
SLC2A4,ARAP3,TRIP10,PPM1J,HEBP1,FXYD3,XYLT1,GABRG2,SIX4,M6PR,RABGGTA,SESN3,CTGF,SH3BP1,ZFP36,BAX,BCL6,IQCD,NPTXR,ARL4D,GAD1,TPCN1,HES1,ACVR1C,NR4A1,KIF1C,TCF7,NPC2,RASGRP2,NFKBIA,S100A5,PITPNA,OSR1,NRGN |
| 1.505e-02 | -4.20 | KAYO_AGING_MUSCLE_UP | MSigDB lists | KAYO_AGING_MUSCLE_UP | 234 | 34 | 17758 | 1761 |
GRN,SLC2A4,HSPG2,CALB2,IL18,H1FX,EPCAM,FUT8,AOX1,TFAP2A,RFX5,NCAM1,DLG3,SGCB,FAH,HMMR,PTPRU,EZR,PRKAR2B,RNF113A,ELK1,CD83,ONECUT1,JAK1,FGFR2,SCG2,RBL1,HNRNPH2,CSF1,MADD,NR4A3,NRG1,GLA,LTBP2 |
| 1.505e-02 | -4.20 | - | gene3d domains | 1.10.150.50 | 104 | 19 | 9988 | 1080 |
ARAP2,ARAP3,EPHA4,PPFIBP2,EPHA1,SAMD9,ETS1,ELF3,SCML1,DGKH,EPHA10,ANKS6,ETS2,STIM1,ANKS1B,ELF5,SFMBT1,EPHB4,ETV7 |
| 1.506e-02 | -4.20 | UBE2I (ubiquitin conjugating enzyme E2I) | protein interactions | 7329 | 406 | 58 | 16036 | 1726 |
PRKAA2,BCAM,SLC2A4,FOXM1,PPM1J,THRA,TSC22D3,IQGAP1,SOX9,HABP4,TP53,CDCA8,CRABP2,ETS1,SH3KBP1,LMNA,MECOM,TOP2A,DTX3L,ADD3,SCNN1A,HSF2,SP100,RNF128,PTEN,MKRN3,MITF,TFAP2A,TRIM21,THRB,MX1,SIRT1,KCNIP3,RIPK2,NR3C1,CORO2A,RC3H2,PPARA,TFAP2C,PRKRA,ELK1,FOS,CDK1,RANBP9,FAS,NIN,PIAS3,KCNK1,NR1D2,NFKBIA,HDAC1,AURKA,KLF5,HMGA1,HSPB1,NR3C2,HIPK3,GOLGB1 |
| 1.508e-02 | -4.19 | FOXM1 transcription factor network | Pathway Interaction DB | foxm1pathway | 37 | 11 | 2227 | 331 |
PLK1,CCND1,ONECUT1,CENPA,FOXM1,ETV5,NEK2,CCNB1,CCNB2,FOS,CDK1 |
| 1.509e-02 | -4.19 | Irinotecan Action Pathway | SMPDB pathways | SMP00433 | 21 | 7 | 978 | 131 |
DNAJB11,PDIA6,ERP29,ABCB1,ABCC1,PDIA4,ABCG2 |
| 1.509e-02 | -4.19 | Irinotecan Metabolism Pathway | SMPDB pathways | SMP00600 | 21 | 7 | 978 | 131 |
DNAJB11,PDIA6,ERP29,ABCB1,ABCC1,PDIA4,ABCG2 |
| 1.511e-02 | -4.19 | KEGG_VIRAL_MYOCARDITIS | MSigDB lists | KEGG_VIRAL_MYOCARDITIS | 68 | 13 | 17758 | 1761 |
CCND1,HLA-B,CASP3,CD55,HLA-E,HLA-F,CASP9,MYH14,HLA-C,CD40,SGCB,DAG1,HLA-A |
| 1.511e-02 | -4.19 | Interferon gamma signaling | REACTOME pathways | R-HSA-877300 | 92 | 17 | 8202 | 867 |
TRIM8,TRIM2,HLA-E,HLA-F,TRIM68,HLA-A,SOCS3,HLA-B,SP100,JAK1,IRF2,TRIM21,IRF7,HLA-C,OAS3,NCAM1,TRIM62 |
| 1.515e-02 | -4.19 | E-cadherin signaling in keratinocytes | Pathway Interaction DB | ecadherin_keratinocyte_pathway | 19 | 7 | 2227 | 331 |
PLCG1,RHOA,AKT1,CDH1,FMN1,PIK3R1,PIK3CA |
| 1.516e-02 | -4.19 | M_PHASE | MSigDB lists | M_PHASE | 113 | 19 | 17758 | 1761 |
PLK1,REC8,ZWINT,DLGAP5,CIT,NDC80,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDCA5,NEK2,AURKA,BUB1,CENPE,UBE2C,MPHOSPH9,ESPL1 |
| 1.516e-02 | -4.19 | DAIRKEE_TERT_TARGETS_DN | MSigDB lists | DAIRKEE_TERT_TARGETS_DN | 113 | 19 | 17758 | 1761 |
PACSIN2,BCL9,STAU2,LMCD1,HES2,MGAT5B,AMDHD1,ARHGEF26,ZFYVE16,B3GALNT1,ACAP2,GATA2,DACT1,CALD1,UBE2J1,PPM1H,EFNA5,SH3BGRL2,CMTM4 |
| 1.516e-02 | -4.19 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 113 | 19 | 17758 | 1761 |
SEC23A,CPEB4,CAST,GALNT7,FNDC3A,NFIB,ARF4,RASA1,IRS2,SLC6A6,WDR44,DPYSL2,CSNK1G1,RAP2C,UBE2J1,NCAM1,SEMA3A,CPEB2,ATP2B1 |
| 1.517e-02 | -4.19 | SH2 | interpro domains | IPR000980 | 113 | 19 | 18293 | 1814 |
INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,BCAR3,PLCG1,TNS3,JAK1,SHC3,RINL,PLCG2,JAK3,SYK,SOCS5 |
| 1.525e-02 | -4.18 | cellular response to oxygen levels | biological process | GO:0071453 | 133 | 22 | 16441 | 1675 |
SIRT1,PINK1,NKX3-1,SLC2A4,CPEB4,AKT1,EPAS1,TP53,RGCC,SLC11A2,PDK3,CCNB1,LMNA,FAS,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,CPEB2,EGLN1 |
| 1.527e-02 | -4.18 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4392 | 472 | 17775 | 1757 |
HECA,ACACB,GAA,ADD1,SSH1,HSPG2,DNAJC3,HEXB,RET,TAP1,FBXO2,NRG2,VASH1,FAM101B,LTBP3,EPDR1,CDKN2C,CYP1A1,RGS3,CABP1,OSBPL3,PAQR5,ALDH1A3,KLF3,AOX1,KCNS3,PIK3CA,ATRNL1,CRY2,HYLS1,MTMR11,RCAN3,APOBEC3G,ERAP2,DNAAF3,NWD1,SPEF2,SMARCA2,TNIP1,SPATA18,ACVR1C,CASP9,CDA,KIF13A,LOXL2,CCNF,COL12A1,PIAS3,ENPP1,DNM1L,ANKRD6,PLK2,GNPTAB,FAM114A1,NOD2,DHTKD1,TANC2,LZTS1,FGD1,DDX58,SCN5A,FRMD4A,TBC1D1,ITGA6,DGKQ,RAB23,KIF23,SLC1A3,MERTK,LMNA,KIAA1161,MARCH8,DOPEY2,CYR61,ZNRF2,FAM189A1,MEGF8,FLRT3,AIM1,OPN3,SORL1,CADPS2,ALPK1,PIKFYVE,ZMYM1,PPP6R1,RIMS2,IGSF3,SOCS5,GFPT1,KCNJ12,SLC37A1,MFI2,PRSS23,ADCK3,MICB,AMER1,MYBL2,ATP8B3,ANTXR1,GNA11,FRMD4B,FAS,DGKH,NCOA3,AP1AR,TJP3,FAM64A,ETS2,SEMA4D,DCK,ITPR1,FAM83D,AGBL5,CABIN1,DRP2,MAP3K5,PLIN3,PER3,IFIH1,TMEM173,XDH,ADAMTS16,EHD1,DOCK9,PLA2G4A,MTM1,SPRED1,PAPSS2,NLRX1,GALNT12,DDIT4L,PTTG1,RGS20,TESK2,PKP2,KCTD12,CYP39A1,EPS8L2,APLP2,MUC16,FAM46A,CDH1,SH3BP1,RTKN2,LGMN,PHKA2,MYT1,NR2C1,NAGA,SCN3A,ATG4D,DOCK4,MX1,CAMSAP3,SEC23A,COL6A2,RIPK2,FOXJ2,SYNE2,PRKCQ,PYGO1,ITPR3,ALCAM,ATP10D,ZNF469,NFIX,NIN,EPHA10,WFS1,CORO1C,SLC9A6,TRIOBP,PLEKHG1,FAM195A,SLC27A1,KLF5,NRG1,MLKL,COBL,CTHRC1,PCOLCE,ESRP1,CENPI,RASSF7,PBX3,CYB561,APOBEC3H,NUCB2,PLPPR4,GSTP1,ETS1,DNAH3,BEX2,NEO1,CXCL16,ADD3,ARSG,PTEN,FJX1,TMBIM6,IGFBP2,ERBB3,NPTXR,TPCN1,PARP9,AMOTL2,TGIF1,ARAP2,SHMT1,FMN1,MFSD2B,PIK3R1,FURIN,MYEOV,DIAPH2,LRRC1,GRTP1,MAMDC4,PLOD2,FGFR2,RAB11FIP2,ACVRL1,DBI,ABCB1,PPM1H,ERAP1,CENPE,FHL1,FZD5,NCAPG2,DEF6,OCLN,TMEM131,RGMA,JARID2,LTBP1,NMRK1,BCAM,KIAA1462,CAMKK1,CPT2,FHDC1,NENF,DNER,TMC1,SPTB,SH3KBP1,PTCHD4,SUSD2,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,TSPAN6,PHTF1,ANKFN1,DLG1,TMEM143,ABCA2,MYH14,ANO4,TECR,SLC39A10,TLN2,NEB,CCDC38,CYP1B1,ZNF462,THRB,MCTP1,CD55,RGAG1,EZR,CR2,IDH1,KDM4D,OPTN,HS6ST1,PLCH1,NEIL1,HPSE,MAP2,P4HA2,ZNF367,MADD,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,RAP1GAP,CAPN1,PRSS8,GRN,FAM213B,ARAP3,LGALS3,PEX6,RASA2,PYROXD2,ABCG2,PDCL,HES2,CNTNAP2,PHLPP1,ADAMTSL4,FBLN1,ANO1,UBE2Q2,IGF1R,FRAS1,KCNN4,TBCD,COL6A1,FXYD5,ZRANB1,PLCB2,CCDC88A,DPYSL5,PODXL2,SPATA13,GYLTL1B,VWA1,BTN3A2,TCF7,RANBP9,MUM1L1,RASGRP2,GNAS,FECH,COL13A1,H1F0,ITGA7,CGREF1,NLRC5,RHOBTB2,YOD1,DONSON,LTBP2,PLD1,ZDBF2,SHROOM2,JAK3,USP43,CCNE2,NCKAP5,SORBS1,NF2,UPF3B,TP53,MORC4,COL18A1,ERBB2,SLC7A2,ARHGEF16,SYTL2,CYP26A1,IER3,PDGFA,SS18,ZNF687,ARTN,WDR44,PLCG2,BCL6,ESPN,NOTCH3,OAS3,ECE1,MINPP1,SCN2A,PPIF,AKT1,SLC39A8,OSTM1,ACO1,PTGER4,DUSP4,DOCK5,ATP13A2,ARHGAP35,DUOX1,PTPRJ,ALDH5A1,BFSP1,ABHD12,PTK7,STK38,ADAMTS14,SPTBN5,IRF7,ANXA9,ST3GAL1,REEP4,ABCA1,GLIS3,COL9A3,TM2D2,CDH22,KLHL13,ARHGEF11,MACC1,RUSC2,LRP4,COL4A5,GDF15,NOTUM,SBF1,DSE,CRABP2,LBR,SH2D4A,FZD6,TMEM63A,HDAC9,CD109,KIF5B,IL17RB,IRF2BPL,CARD8,ADORA1,MLPH,LLGL2,TOX2,TFAP2A,FAM63A,KIAA0319,TSPAN13,BUB1,IQGAP3,C12orf75,MYO5A,GCNT1,IGDCC4,NFE2L3,HMMR,SUN2,MOSPD2,NR4A1,PLAUR,ASPM,SYBU,LITAF,PPARA,OGDHL,LRRC66,TTC7A,PRICKLE1,MAML2,COL7A1,RNPEP,BCAR1,TXNDC11,BBS2,LEPR,HLA-B,SERPINA1,FAT4,TWSG1,NAT1,NETO2,PPP2R3C,PLOD3,ICOSLG,SOX8,TBC1D4,PTGES,AHR,ARHGEF4,GOLGB1 |
| 1.528e-02 | -4.18 | OXFORD_RALA_OR_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_UP | 47 | 10 | 17758 | 1761 |
CCND1,CCNE2,PPIF,ZWINT,HMGA1,PLXNA1,SLC20A1,UBE2C,CDK1,SAC3D1 |
| 1.528e-02 | -4.18 | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | MSigDB lists | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | 47 | 10 | 17758 | 1761 |
WEE1,SOX9,CLDN4,MAP3K5,FZD5,CCNB2,DDR1,MERTK,RARG,ELF3 |
| 1.528e-02 | -4.18 | OLSSON_E2F3_TARGETS_DN | MSigDB lists | OLSSON_E2F3_TARGETS_DN | 47 | 10 | 17758 | 1761 |
PLK1,TIMP3,NFKBIA,PTTG1,MYBL2,CD9,MAL2,UBE2C,LBR,CDK1 |
| 1.528e-02 | -4.18 | PID_DELTA_NP63_PATHWAY | MSigDB lists | PID_DELTA_NP63_PATHWAY | 47 | 10 | 17758 | 1761 |
TOP2A,HES1,PPP2R5A,ITGA3,ITCH,AXL,NRG1,WWP1,RAB38,CCNB2 |
| 1.529e-02 | -4.18 | V$SOX5_01 | MSigDB lists | V$SOX5_01 | 251 | 36 | 17758 | 1761 |
MRC2,GRHL2,CPEB4,KLHL13,TSC22D3,TP53,ARFGEF1,MORC4,COL4A5,DHRS3,ZNF385B,RCN1,FOXP2,PRICKLE3,LMO4,ATRNL1,TWIST1,TACSTD2,PIM1,NCAM1,ARMCX6,CLIP2,ZNF365,MOSPD2,NR4A1,AMFR,NFIB,G2E3,RBM47,FGFR2,HOXA9,PELI2,EIF4EBP2,SEMA3A,TOB1,NR2C2 |
| 1.529e-02 | -4.18 | V$BACH1_01 | MSigDB lists | V$BACH1_01 | 251 | 36 | 17758 | 1761 |
ENO2,NUAK1,CAMKK1,NDRG2,RNF182,FAM81A,LMNA,SHC3,ABCA2,SGK1,TNFRSF12A,ABCD1,NTN4,MYH14,TAGLN2,PIM1,TRAK2,TRIM8,ELK3,LONRF3,CAPN6,RGAG1,STRADB,TMEM151A,COL7A1,ATP1B1,AIF1L,ZFAND5,PRX,GABARAPL1,MAP2,CAB39,HMGA1,HS3ST3B1,UBE2C,SNPH |
| 1.533e-02 | -4.18 | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | 6 | 3 | 17775 | 1757 |
KIF5B,ERBB2,TP53 |
| 1.533e-02 | -4.18 | central_nervous_system-brain-glioma-gliomatosis_cerebri | COSMIC cancer mutations | central_nervous_system-brain-glioma-gliomatosis_cerebri | 6 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 1.533e-02 | -4.18 | central_nervous_system-frontoparietal-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontoparietal-glioma-oligodendroglioma_Grade_III | 6 | 3 | 17775 | 1757 |
CDKN2C,IDH1,TP53 |
| 1.533e-02 | -4.18 | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_II | 6 | 3 | 17775 | 1757 |
CDKN2C,IDH1,PTEN |
| 1.533e-02 | -4.18 | skin-flank-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-flank-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 1.533e-02 | -4.18 | meninges-meningioma-angiomatous | COSMIC cancer mutations | meninges-meningioma-angiomatous | 6 | 3 | 17775 | 1757 |
CDKN2C,NF2,AKT1 |
| 1.533e-02 | -4.18 | skin-back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-back-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 1.533e-02 | -4.18 | angiomatous | COSMIC cancer mutations | angiomatous | 6 | 3 | 17775 | 1757 |
CDKN2C,NF2,AKT1 |
| 1.533e-02 | -4.18 | lung-right_middle_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_middle_lobe-carcinoma-adenocarcinoma | 6 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 1.533e-02 | -4.18 | spindle_cell | COSMIC cancer mutations | spindle_cell | 6 | 3 | 17775 | 1757 |
GNAS,IDH1,PIK3CA |
| 1.533e-02 | -4.18 | gliomatosis_cerebri | COSMIC cancer mutations | gliomatosis_cerebri | 6 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 1.533e-02 | -4.18 | psammomatous | COSMIC cancer mutations | psammomatous | 6 | 3 | 17775 | 1757 |
CDKN2C,NF2,AKT1 |
| 1.533e-02 | -4.18 | endometrium-carcinoma-mixed_endometrioid_and_clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_endometrioid_and_clear_cell_carcinoma | 6 | 3 | 17775 | 1757 |
FGFR2,PTEN,PIK3CA |
| 1.533e-02 | -4.18 | skin-abdomen-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-abdomen-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 1.533e-02 | -4.18 | meninges-meningioma-psammomatous | COSMIC cancer mutations | meninges-meningioma-psammomatous | 6 | 3 | 17775 | 1757 |
CDKN2C,NF2,AKT1 |
| 1.533e-02 | -4.18 | skin-lower_back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-lower_back-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 1.533e-02 | -4.18 | central_nervous_system-temporal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-oligodendroglioma_Grade_II | 6 | 3 | 17775 | 1757 |
CDKN2C,IDH1,PTEN |
| 1.533e-02 | -4.18 | gangliocytoma | COSMIC cancer mutations | gangliocytoma | 6 | 3 | 17775 | 1757 |
IDH1,PTEN,GNA11 |
| 1.533e-02 | -4.18 | rhabdoid | COSMIC cancer mutations | rhabdoid | 6 | 3 | 17775 | 1757 |
NF2,AKT1,IDH1 |
| 1.533e-02 | -4.18 | skin-upper_leg-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-upper_leg-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 1.536e-02 | -4.18 | cell cortex part | cellular component | GO:0044448 | 120 | 20 | 17570 | 1756 |
MYO5B,LASP1,NF2,MPP1,SEPT6,EZR,ANLN,SPTB,PLEKHH2,SCNN1A,CDH1,STIM1,LLGL2,CALD1,EXOC8,SPTBN5,CTTN,SHROOM2,MYRIP,GM2A |
| 1.537e-02 | -4.18 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | 193 | 29 | 17758 | 1761 |
FBLIM1,CENPA,PINK1,UGP2,ADD1,GNPDA1,MRPS15,CPT2,CDC20,MGAT4B,TESK2,FBXO9,FAM198B,MGST2,HDAC6,NUCB2,TMPRSS4,FAM111A,WEE1,ELMO2,WFS1,TBCD,PNPLA6,NR4A3,FAM117A,PLEKHF1,ERBB3,PLIN3,MYO5A |
| 1.537e-02 | -4.18 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | 193 | 29 | 17758 | 1761 |
TGIF1,ARAP2,MMD,TSC22D3,XYLT1,UTRN,CXorf57,SELL,PBX3,CR2,TRMT2B,DDR1,ADRBK2,CD83,ENDOD1,BANK1,ETS2,CDK19,PHLPP2,AIM1,DTX4,SORL1,DUSP10,KLF9,PIK3CD,PHKA2,TRAF5,NR3C2,KLF7 |
| 1.537e-02 | -4.18 | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDM_DN | 193 | 29 | 17758 | 1761 |
SORT1,CCDC109B,TNIP1,ADD1,BCL9,FAM134A,TAP1,TFAP2C,F11R,DHRS3,ARHGEF40,SNX12,TMEM63A,ARHGAP35,ARSG,FRYL,PAPSS1,ABCD1,MDFIC,TMOD2,SERPINB6,HMGA1,FHL1,OAS3,RGS14,DGKG,MYL12B,TMEM131,PAQR7 |
| 1.537e-02 | -4.18 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | 193 | 29 | 17758 | 1761 |
MAP3K3,CASP3,FADS2,TRIM8,IFITM3,DAP,BLVRB,ARL4C,C6orf106,BLVRA,BCL2L1,ATP8B3,ANLN,CDK1,LBR,TTC21B,NUDT16,APLP2,CORO1C,MKRN3,CST3,PPM1H,BMP1,IRF7,C10orf54,UBE2C,NCOA2,SMAGP,SNX30 |
| 1.537e-02 | -4.18 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | 193 | 29 | 17758 | 1761 |
TPRN,MBP,DLGAP5,CKAP2,LPGAT1,MPP1,OXR1,CUL4B,HABP4,CCDC34,TESK2,AES,RNPEP,CDK1,CMTM6,TMPRSS4,ANKRD10,ENDOD1,GNAS,MSL1,SLC25A4,KBTBD2,BDH1,N4BP3,IL31RA,ARRB1,RPN2,ACOX2,GCNT1 |
| 1.537e-02 | -4.18 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | 193 | 29 | 17758 | 1761 |
CMAS,ZWINT,SDC4,ERI2,C5orf30,HTATIP2,GGH,PKMYT1,BCL2L1,CCNF,GTF2A2,IDH1,PSMA4,KDM4D,SLCO4A1,PSMD1,FAM64A,P4HA2,CSTF2,BUB1,DONSON,FAR2,SGCB,CCNB2,ACOT7,FAH,SEPHS1,CYP1B1,GCNT1 |
| 1.537e-02 | -4.18 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 193 | 29 | 17758 | 1761 |
MAP3K3,MX1,TIMP2,COL6A2,PAPSS2,NQO1,ATP9A,FAM134A,DIAPH2,SPR,FAM101B,TYSND1,BSDC1,CHPF,NFIX,AKIRIN1,NCOA3,ST5,RPL12,RPS6KA2,ADORA1,CA2,RALGPS2,NR1D2,FOSB,PITPNA,SERPINI1,NOTCH3,ABCG1 |
| 1.537e-02 | -4.18 | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | 193 | 29 | 17758 | 1761 |
SUN1,CENPA,SEC61B,GNPDA1,ITCH,ITGA6,FAM198B,LBR,EFNB1,STX3,FUCA1,GALNT3,SS18,ALDH3B1,GNB5,TIMM8A,SH3BP1,DOLPP1,SIVA1,PLCG2,SORL1,IRF2,ARRB1,MDH1,C10orf54,RELL1,MYL12B,RAB3IL1,JARID2 |
| 1.537e-02 | -4.18 | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDM_DN | 193 | 29 | 17758 | 1761 |
SUN2,TRIM2,PARP12,UPF3B,MMADHC,ARFRP1,ERBB2IP,TP53INP2,LTBP3,DNAJB9,ARHGAP35,RNF128,RBL1,GDE1,KCNN4,IL6ST,KBTBD2,NR4A3,EIF4EBP2,RP2,DLG3,ZMIZ1,PTPRE,SLC25A30,TMEM9,E2F8,CPPED1,CRTAP,STARD3NL |
| 1.539e-02 | -4.17 | vpr (p15) | protein interactions | 155807 | 562 | 77 | 16036 | 1726 |
LAMP1,CASP3,FOXM1,CUL4B,TP53,FTH1,BCL2L1,ISOC2,CCNB1,PRKACA,RAD23A,WEE1,CDH1,TUBG1,VAT1,IFIT1,ACSL4,SCARA3,APOBEC3G,PLK1,MX1,CENPA,AKT1,CASP9,EZR,ARHGDIB,PRKAR2B,RAD17,CD40,SLC25A5,CDK1,PPP2R5A,SLC25A4,DNM1L,HDAC1,IRF7,HSPB1,PCSK5,DDX58,PRKAA2,GGA1,ITGA6,DNAJB2,MTL5,ASAH1,PDIA3,CTSZ,GSTP1,LMNA,PPP2R3A,HLA-A,GNS,RRBP1,BAX,TAGLN2,HLA-C,ULBP2,NUP85,ACBD5,DDB2,RHOA,IFITM3,NR3C1,NR4A1,IFIT3,FOS,CD83,FAS,MAPKAPK2,HLA-B,SCARB2,PRKAG2,NFKBIA,CTSA,CCNB2,AHR,CD33 |
| 1.541e-02 | -4.17 | MARSON_FOXP3_TARGETS_UP | MSigDB lists | MARSON_FOXP3_TARGETS_UP | 61 | 12 | 17758 | 1761 |
SWAP70,SNX18,SH3BGRL,S100A4,TGFBR1,ITGAV,DUSP4,ETS1,TIAM1,GM2A,S100A6,CYB5A |
| 1.541e-02 | -4.17 | LEE_LIVER_CANCER_E2F1_DN | MSigDB lists | LEE_LIVER_CANCER_E2F1_DN | 61 | 12 | 17758 | 1761 |
MAPKAPK2,KLK5,AASS,ITPR1,HAL,DBI,NETO2,ABCG2,GOT1,MDH1,OAT,REPS1 |
| 1.541e-02 | -4.17 | CHANG_IMMORTALIZED_BY_HPV31_DN | MSigDB lists | CHANG_IMMORTALIZED_BY_HPV31_DN | 61 | 12 | 17758 | 1761 |
THRB,MX1,TNRC6C,PHF7,PTPRU,KLK6,KLK7,SAMD9,IFIT1,SULT2B1,FOS,PRIM1 |
| 1.542e-02 | -4.17 | ensheathment of neurons | biological process | GO:0007272 | 88 | 16 | 16441 | 1675 |
MBP,UGT8,AKT1,HEXB,ERBB2,KLK6,MPP5,DAG1,PRX,CNTNAP1,PTEN,CD9,NRG1,PIKFYVE,SCN2A,MYO5A |
| 1.542e-02 | -4.17 | axon ensheathment | biological process | GO:0008366 | 88 | 16 | 16441 | 1675 |
MBP,UGT8,AKT1,HEXB,ERBB2,KLK6,MPP5,DAG1,PRX,CNTNAP1,PTEN,CD9,NRG1,PIKFYVE,SCN2A,MYO5A |
| 1.543e-02 | -4.17 | POOLA_INVASIVE_BREAST_CANCER_UP | MSigDB lists | POOLA_INVASIVE_BREAST_CANCER_UP | 268 | 38 | 17758 | 1761 |
CCNE2,SPC25,DLGAP5,PTTG1,RET,NDC80,SELL,IL18,GDF15,CNTNAP2,GPSM2,IL18R1,FANCI,TOP2A,APOBEC3B,CTSC,IMPAD1,NEK2,CCDC88A,LAMP3,CKS2,CENPA,KIF20A,ASPM,PBK,PLAUR,STAT4,CDC20,NUSAP1,CD40,KIF11,STK17B,CDK1,BANK1,AURKA,CCNB2,CPPED1,MELK |
| 1.543e-02 | -4.17 | Salivary secretion | KEGG pathways | hsa04970 | 89 | 17 | 6908 | 758 |
CALM1,CALM3,ITPR2,ATP1B1,ITPR3,PRKACA,GNAS,CALM2,ATP1A1,KCNN4,CST3,ITPR1,PRKG1,ATP1B3,SLC12A2,PLCB2,ATP2B1 |
| 1.543e-02 | -4.17 | Salivary secretion | KEGG pathways | ko04970 | 89 | 17 | 6908 | 758 |
CALM1,CALM3,ITPR2,ATP1B1,ITPR3,PRKACA,GNAS,CALM2,ATP1A1,KCNN4,CST3,ITPR1,PRKG1,ATP1B3,SLC12A2,PLCB2,ATP2B1 |
| 1.545e-02 | -4.17 | Activation of PPARGC1A (PGC-1alpha) by phosphorylation | REACTOME pathways | R-HSA-2151209 | 10 | 4 | 8202 | 867 |
PRKAA2,MAPK11,PRKAG2,MAPK12 |
| 1.545e-02 | -4.17 | TNF signaling pathway | KEGG pathways | hsa04668 | 110 | 20 | 6908 | 758 |
CASP3,AKT1,IL15,ITCH,PIK3R1,FOS,IL18R1,FAS,SOCS3,DNM1L,CSF1,NFKBIA,NOD2,PIK3CA,MAPK11,MLKL,PIK3CD,MAP3K5,TRAF5,MAPK12 |
| 1.545e-02 | -4.17 | TNF signaling pathway | KEGG pathways | ko04668 | 110 | 20 | 6908 | 758 |
CASP3,AKT1,IL15,ITCH,PIK3R1,FOS,IL18R1,FAS,SOCS3,DNM1L,CSF1,NFKBIA,NOD2,PIK3CA,MAPK11,MLKL,PIK3CD,MAP3K5,TRAF5,MAPK12 |
| 1.546e-02 | -4.17 | DLG4 (discs, large homolog 4 (Drosophila)) | protein interactions | 1742 | 119 | 21 | 16036 | 1726 |
DLGAP1,KCNJ12,SCN5A,FZD4,CIT,GRIN1,ERBB2,IL13RA1,YES1,ERBB2IP,LRRC1,FZD7,RAD23A,KIF13B,SIPA1L1,DLG1,GRIN2D,NRG1,DLG3,WNT3A,MAPK12 |
| 1.547e-02 | -4.17 | Ryanodine_recept-rel | interpro domains | IPR015925 | 6 | 3 | 18293 | 1814 |
ITPR2,ITPR3,ITPR1 |
| 1.547e-02 | -4.17 | RIH_assoc-dom | interpro domains | IPR013662 | 6 | 3 | 18293 | 1814 |
ITPR2,ITPR3,ITPR1 |
| 1.547e-02 | -4.17 | F-box-assoc_dom | interpro domains | IPR007397 | 6 | 3 | 18293 | 1814 |
FBXO6,FBXO27,FBXO2 |
| 1.547e-02 | -4.17 | PET_domain | interpro domains | IPR010442 | 6 | 3 | 18293 | 1814 |
PRICKLE1,PRICKLE3,LMCD1 |
| 1.547e-02 | -4.17 | RIH_dom | interpro domains | IPR000699 | 6 | 3 | 18293 | 1814 |
ITPR2,ITPR3,ITPR1 |
| 1.547e-02 | -4.17 | p53/RUNT-type_TF_DNA-bd | interpro domains | IPR012346 | 6 | 3 | 18293 | 1814 |
RUNX3,RUNX2,TP53 |
| 1.547e-02 | -4.17 | Hydantoinase/dihydroPyrase | interpro domains | IPR011778 | 6 | 3 | 18293 | 1814 |
DPYSL5,DPYSL2,DPYSL3 |
| 1.547e-02 | -4.17 | Ins145_P3_rcpt | interpro domains | IPR014821 | 6 | 3 | 18293 | 1814 |
ITPR2,ITPR3,ITPR1 |
| 1.547e-02 | -4.17 | Na_trans_cytopl | interpro domains | IPR024583 | 6 | 3 | 18293 | 1814 |
SCN5A,SCN2A,SCN3A |
| 1.547e-02 | -4.17 | CROSBY_E2F4_TARGETS | MSigDB lists | CROSBY_E2F4_TARGETS | 6 | 3 | 17758 | 1761 |
CENPE,PTTG1,NDC80 |
| 1.547e-02 | -4.17 | chr6p11 | MSigDB lists | chr6p11 | 6 | 3 | 17758 | 1761 |
ENPP4,ENPP5,RAB23 |
| 1.547e-02 | -4.17 | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN | MSigDB lists | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN | 6 | 3 | 17758 | 1761 |
SERPINB1,PLOD2,EDNRA |
| 1.547e-02 | -4.17 | ZERBINI_RESPONSE_TO_SULINDAC_DN | MSigDB lists | ZERBINI_RESPONSE_TO_SULINDAC_DN | 6 | 3 | 17758 | 1761 |
CCNB1,CCNB2,CDK1 |
| 1.547e-02 | -4.17 | OHASHI_AURKA_TARGETS | MSigDB lists | OHASHI_AURKA_TARGETS | 6 | 3 | 17758 | 1761 |
AURKA,CENPA,DLGAP5 |
| 1.547e-02 | -4.17 | SMID_BREAST_CANCER_NORMAL_LIKE_DN | MSigDB lists | SMID_BREAST_CANCER_NORMAL_LIKE_DN | 6 | 3 | 17758 | 1761 |
EPN3,AP1M2,CDS1 |
| 1.547e-02 | -4.17 | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | MSigDB lists | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | 6 | 3 | 17758 | 1761 |
AKR1B1,OAT,HSPB1 |
| 1.547e-02 | -4.17 | IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM | MSigDB lists | IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM | 6 | 3 | 17758 | 1761 |
CDKN1B,ARHGEF26,NEO1 |
| 1.547e-02 | -4.17 | OHM_EMBRYONIC_CARCINOMA_UP | MSigDB lists | OHM_EMBRYONIC_CARCINOMA_UP | 6 | 3 | 17758 | 1761 |
CDH1,GSTP1,DAPK1 |
| 1.548e-02 | -4.17 | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | MSigDB lists | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | 121 | 20 | 17758 | 1761 |
ING1,UPF3B,THRA,CAST,H2AFV,NFIB,STX3,SIRPA,RASA1,KIF5B,RCN1,PDGFA,DNAJC10,APLP2,SCARB2,PGRMC1,FAM63A,TPST1,PLD1,RELL1 |
| 1.548e-02 | -4.17 | CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 121 | 20 | 17758 | 1761 |
PDGFC,MBP,UGT8,PBX3,NCKAP1,DNER,GSTP1,HPCAL4,CDK5R1,FOXP2,ALDH5A1,PTEN,SHC3,LHX6,SERPINI1,SOX8,DRP2,SHROOM2,ALDH3A2,JARID2 |
| 1.548e-02 | -4.17 | ACAGGGT,MIR-10A,MIR-10B | MSigDB lists | ACAGGGT,MIR-10A,MIR-10B | 121 | 20 | 17758 | 1761 |
LTBP1,TRIM2,EPHA4,CTDSPL,TFAP2C,PPP1R14C,SDC1,SIX4,NRP2,APPBP2,NFIX,CTNNBIP1,DAZAP1,CSNK1G1,ZNF367,NR4A3,BCL6,CNNM4,KLF11,USF2 |
| 1.550e-02 | -4.17 | GENTILE_UV_RESPONSE_CLUSTER_D4 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D4 | 54 | 11 | 17758 | 1761 |
CTGF,UAP1,GATA2,ZFP36,RAPGEF2,GNE,TPST1,AURKA,CCNB1,ARF6,FZD7 |
| 1.550e-02 | -4.17 | REACTOME_PI_3K_CASCADE | MSigDB lists | REACTOME_PI_3K_CASCADE | 54 | 11 | 17758 | 1761 |
AKT1,PTEN,FGFR2,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,PHLPP1,FGF19,GAB1 |
| 1.550e-02 | -4.17 | OUILLETTE_CLL_13Q14_DELETION_DN | MSigDB lists | OUILLETTE_CLL_13Q14_DELETION_DN | 54 | 11 | 17758 | 1761 |
SIPA1L2,ENO2,SERPINE2,ETV5,MYBL2,CYB561,PHLPP1,DDR1,CDK5R1,ESYT2,PARP9 |
| 1.555e-02 | -4.16 | REACTOME_CELL_CYCLE | MSigDB lists | REACTOME_CELL_CYCLE | 397 | 53 | 17758 | 1761 |
CCNE2,SPC25,CEP70,HJURP,PSME2,CENPI,PTTG1,NDC80,CDCA8,TP53,KIF23,PSMD10,NUF2,PSME1,CCNB1,PRKACA,CENPN,LMNA,CCND1,CDKN2C,WEE1,PSMD1,CNTRL,NEK2,PLK4,CDKN1B,TUBG1,BUB1,CDKN2D,NUP85,REC8,PLK1,SUN2,ZWINT,CENPA,PSMB4,KIF20A,CDC20,SYNE2,MYBL2,PRKAR2B,PKMYT1,RAD17,CDK1,PSMA4,PRIM1,PPP2R5A,RBL1,HDAC1,AURKA,CEP41,UBE2C,CCNB2 |
| 1.555e-02 | -4.16 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 185 | 28 | 17758 | 1761 |
NFE2L3,ORAI2,PDGFC,CENPA,B3GNT2,TP53,PSME1,ATP1B1,ITPR2,AIF1L,SLC25A5,ADRBK2,AHRR,RCN1,SLC6A6,PTEN,CTSC,LMO4,PLEKHG1,BAX,PIK3C2B,RFX5,HMGA1,FAR2,ZMIZ1,TIPARP,MCCC2,ABCC1 |
| 1.555e-02 | -4.16 | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | 185 | 28 | 17758 | 1761 |
ATP8A1,HLA-F,TSC22D3,SYNE2,CACNA2D2,BTN3A2,EZR,BTN3A1,PRKCQ,TCF7,YES1,ITPR3,ETS1,C11orf95,STK17B,LTBP3,PRIM1,TRANK1,STK38,PASK,INPP4B,FAM102A,TBC1D4,MYLIP,NR3C2,APOBEC3G,DOCK9,EHD1 |
| 1.556e-02 | -4.16 | PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) | protein interactions | 5300 | 232 | 36 | 16036 | 1726 |
TP53,ERBB2,CCNB1,SPR,STIL,ADAMTSL4,REPS1,CHPF,TOP2A,FOXP2,CCND1,WEE1,DAZAP1,BCL6,CDKN1B,TAGLN2,PIM1,LRIF1,MYT1,GPX4,MDFI,PLK1,TNIP1,UBE2A,RUNX3,PKMYT1,ZBTB7B,SNX12,LEPR,CDK1,SOCS3,NCOA3,CARHSP1,NFKBIA,HDAC1,TBC1D4 |
| 1.556e-02 | -4.16 | regulation of natural killer cell mediated immunity | biological process | GO:0002715 | 33 | 8 | 16441 | 1675 |
LAMP1,HLA-B,PVRL2,HLA-E,TAP1,HLA-A,RASGRP1,SMAGP |
| 1.556e-02 | -4.16 | regulation of protein autophosphorylation | biological process | GO:0031952 | 33 | 8 | 16441 | 1675 |
CALM2,PDGFA,ENPP1,CALM1,RAP2C,CALM3,PDGFB,CHP1 |
| 1.558e-02 | -4.16 | NAAA (N-acylethanolamine acid amidase) | protein interactions | 27163 | 50 | 11 | 16036 | 1726 |
MAN2B2,TCTN2,BMP7,GALNS,GLB1L2,FBXO6,ARSB,ARSK,NRP2,SULF2,PCSK5 |
| 1.560e-02 | -4.16 | cell cycle G2/M phase transition | biological process | GO:0044839 | 141 | 23 | 16441 | 1675 |
PLK1,CEP70,FOXM1,MYBL2,PRKAR2B,PKMYT1,CCNB1,PRKACA,BORA,CDK1,OPTN,WEE1,CNTRL,CEP78,ABCB1,PLK4,NEK2,TUBG1,AURKA,CEP41,NDE1,CCNB2,MELK |
| 1.560e-02 | -4.16 | G2/M transition of mitotic cell cycle | biological process | GO:0000086 | 141 | 23 | 16441 | 1675 |
PLK1,CEP70,FOXM1,MYBL2,PRKAR2B,PKMYT1,CCNB1,PRKACA,BORA,CDK1,OPTN,WEE1,CNTRL,CEP78,ABCB1,PLK4,NEK2,TUBG1,AURKA,CEP41,NDE1,CCNB2,MELK |
| 1.561e-02 | -4.16 | Golgi cisterna membrane | cellular component | GO:0032580 | 75 | 14 | 17570 | 1756 |
B3GALT6,CHSY3,GALNT3,NUCB1,SORT1,GOLIM4,FUT2,FUT8,FUT1,B4GALT4,ST3GAL1,BCAP31,NCS1,CHPF |
| 1.563e-02 | -4.16 | regulation of adaptive immune response | biological process | GO:0002819 | 118 | 20 | 16441 | 1675 |
SIRT1,RIPK2,HLA-E,IL27RA,PRKCQ,PKN1,CD40,HLA-A,HLA-B,PVRL2,IL6ST,NOD2,BCL6,DUSP10,IRF7,C10orf54,FZD5,NDFIP1,JAK3,SOCS5 |
| 1.564e-02 | -4.16 | V$HP1SITEFACTOR_Q6 | MSigDB lists | V$HP1SITEFACTOR_Q6 | 218 | 32 | 17758 | 1761 |
NCKAP5,HOXB7,ARFGEF1,LMNA,HDAC9,MECOM,SCML1,PLS3,CTNNBIP1,TFAP4,FOXP2,DPYSL2,RGS3,LMO4,BHLHE41,LHX6,STEAP2,BCL6,DUSP10,CITED2,TGIF1,PIK3R1,RGAG1,PRICKLE1,SFXN5,NFIX,PITX2,TMEM164,TAPBP,HOXA9,AXL,LEMD1 |
| 1.568e-02 | -4.16 | epiboly | biological process | GO:0090504 | 21 | 6 | 16441 | 1675 |
ARHGAP24,RHOA,CYR61,ACVRL1,DDR1,MEGF8 |
| 1.568e-02 | -4.16 | Sertoli cell differentiation | biological process | GO:0060008 | 21 | 6 | 16441 | 1675 |
SOX8,FNDC3A,SDC1,CTSV,CST3,SOX9 |
| 1.568e-02 | -4.16 | ectoderm development | biological process | GO:0007398 | 21 | 6 | 16441 | 1675 |
EPB41L5,NF2,ETS2,ZBTB7B,ITGA6,ELF5 |
| 1.568e-02 | -4.16 | glucan catabolic process | biological process | GO:0009251 | 21 | 6 | 16441 | 1675 |
CALM3,CALM2,PGM1,GAA,PHKA2,CALM1 |
| 1.568e-02 | -4.16 | cellular polysaccharide catabolic process | biological process | GO:0044247 | 21 | 6 | 16441 | 1675 |
CALM3,CALM2,PGM1,GAA,PHKA2,CALM1 |
| 1.569e-02 | -4.15 | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | MSigDB lists | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | 83 | 15 | 17758 | 1761 |
PDGFA,TAPBP,TNIP1,ETS2,PLAUR,NFKBIA,PIM1,PTPRE,PDGFB,PHLDA1,TNFSF9,CD83,SOCS3,IER3,EHD1 |
| 1.569e-02 | -4.15 | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 83 | 15 | 17758 | 1761 |
SORBS1,PTPRJ,IGF1R,REPS2,AKT1,SHC3,EPS8,PIK3R1,ERBB2,ERBB2IP,ROR1,ERBB3,BCAR1,GAB1,FRS3 |
| 1.569e-02 | -4.15 | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP | 83 | 15 | 17758 | 1761 |
B3GALT6,MDK,BANK1,ALDH2,ZNF84,ALDH6A1,RBL1,DCK,SIVA1,ITCH,ZNF320,PHTF1,SGK3,MED30,ATP2B1 |
| 1.570e-02 | -4.15 | positive regulation of dephosphorylation | biological process | GO:0035306 | 46 | 10 | 16441 | 1675 |
CALM2,PINK1,ADORA1,PPP2R5A,NPNT,CALM1,CALM3,CDCA2,SLC39A10,GPLD1 |
| 1.570e-02 | -4.15 | dendrite morphogenesis | biological process | GO:0048813 | 46 | 10 | 16441 | 1675 |
CELSR2,PTEN,MAP2,FMN1,DACT1,LRP4,SLC11A2,SEMA3A,BTBD3,KLF7 |
| 1.570e-02 | -4.15 | PTB | smart domains | SM00462 | 31 | 8 | 9131 | 997 |
TNS3,TBC1D1,SHC3,ANKS1B,EPS8,TNS1,TBC1D4,MAPK8IP1 |
| 1.571e-02 | -4.15 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 177 | 27 | 17758 | 1761 |
COQ10B,UBASH3B,TCF7,HERC6,DPP8,CD83,DCTN6,DTX3L,SCARB2,SESN3,SERPINA1,ELMO2,RAB11FIP2,SLC16A6,PLK2,PELI2,AIM1,NR4A3,PIK3CA,FAM102A,HS3ST3B1,RELL1,GEM,EPB41L4A,MAST4,MYLIP,CKAP4 |
| 1.571e-02 | -4.15 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 27 | 17758 | 1761 |
LAMP2,OPLAH,ZNF395,CD63,GNPDA1,CAST,LRP4,HEXB,PPARA,ASAH1,TMEM144,NPC2,FNDC3A,HDAC6,NTAN1,RHEB,GLCE,M6PR,LRRC42,GNS,AP1AR,RPS6KA2,BRI3,PIK3C2B,DVL2,ATP2B1,RRAGD |
| 1.571e-02 | -4.15 | benign_melanocytic_nevus | COSMIC cancer mutations | benign_melanocytic_nevus | 34 | 8 | 17775 | 1757 |
KIF5B,AKT1,PIK3CA,TP53,GNA11,HLA-A,MYO5A,LMNA |
| 1.571e-02 | -4.15 | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | 34 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,IDH1,GNA11 |
| 1.571e-02 | -4.15 | mouth_floor | COSMIC cancer mutations | mouth_floor | 34 | 8 | 17775 | 1757 |
FGFR2,PTEN,THRA,CENPI,SYNE2,RET,PIK3CA,MELK |
| 1.571e-02 | -4.15 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | 34 | 8 | 17775 | 1757 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,JAK3 |
| 1.571e-02 | -4.15 | bHLH transcription factor binding | molecular function | GO:0043425 | 27 | 7 | 16491 | 1673 |
SIRT1,TWIST1,RUNX2,USF2,TSC22D3,BHLHE41,SOX9 |
| 1.571e-02 | -4.15 | ephrin receptor binding | molecular function | GO:0046875 | 27 | 7 | 16491 | 1673 |
EFNA5,ANKS1B,TIAM1,EFNB1,SIPA1L1,EPHA4,CDK5R1 |
| 1.571e-02 | -4.15 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP | 129 | 21 | 17758 | 1761 |
SUN1,LGR4,ACO1,C5orf30,PBX3,COL4A5,RAB38,B4GALT4,HOXB2,RHEB,CDK5R1,SOX13,MAN2A2,PHF7,METTL7A,DCK,IQCE,HOXA9,WWP1,CTH,METAP2 |
| 1.574e-02 | -4.15 | Phospholipase C-mediated cascade; FGFR2 | REACTOME pathways | R-HSA-5654221 | 51 | 11 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,FGFR2,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 1.574e-02 | -4.15 | positive regulation of cell cycle process | biological process | GO:0090068 | 245 | 36 | 16441 | 1675 |
DLGAP5,CIT,PSME2,CUL4B,TP53,KIF23,PSMD10,PSME1,CCNB1,PRKACA,PDGFB,CCND1,E2F7,CYP1A1,PSMD1,CTGF,IGF1R,PTEN,KIF14,PLK4,CDKN1B,DAB2IP,PLK1,RHOA,PSMB4,RGCC,NUSAP1,PSMA4,CDK5R1,NUDT16,CDCA5,FAM83D,AURKA,UBE2C,E2F8,ESPL1 |
| 1.577e-02 | -4.15 | negative regulation of hydrolase activity | biological process | GO:0051346 | 404 | 55 | 16441 | 1675 |
SPRED1,SORT1,LMTK3,PPP4R4,SERPINE2,RPS6KA1,CAST,IQGAP1,PTTG1,ARFGEF1,TP53,F11R,TIPRL,AIP,SH2D4A,SYTL2,CD109,APLP2,CST3,TMBIM6,SORL1,DAB2IP,CRY2,IFIT1,DLG3,CDKN2D,SPRY2,CHP1,SIRT1,PPIF,CAMSAP3,TIMP2,AKT1,PLAUR,FURIN,COL7A1,PKMYT1,POR,LEPR,PLIN5,FAS,NEIL1,TIMP3,SERPINA1,SEMA4D,SPINT2,SH3BP4,ARRB1,SERPINB6,SERPINI1,SERPINB1,CPEB2,IFI6,EGLN1,ARFGEF3 |
| 1.579e-02 | -4.15 | human chr20q13.1 | chromosome location | human chr20q13.1 | 8 | 3 | 26250 | 1887 |
CTSA,CDH22,MYBL2 |
| 1.581e-02 | -4.15 | oxoglutarate dehydrogenase complex | cellular component | GO:0045252 | 6 | 3 | 17570 | 1756 |
DHTKD1,MRPS36,OGDHL |
| 1.581e-02 | -4.15 | FACIT collagen trimer | cellular component | GO:0005593 | 6 | 3 | 17570 | 1756 |
COL9A3,COL16A1,COL12A1 |
| 1.581e-02 | -4.15 | platelet dense granule | cellular component | GO:0042827 | 6 | 3 | 17570 | 1756 |
LAMP2,CD63,ITPR1 |
| 1.581e-02 | -4.15 | SLC9A1 (solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1) | protein interactions | 6548 | 20 | 6 | 16036 | 1726 |
ARRB1,CA2,LYPD3,CALM1,CHP1,MDFI |
| 1.581e-02 | -4.15 | DIAPH3 (diaphanous-related formin 3) | protein interactions | 81624 | 20 | 6 | 16036 | 1726 |
SIRT1,CENPA,RHOA,CCNB1,HDAC6,CCNB2 |
| 1.581e-02 | -4.15 | PRC1 (protein regulator of cytokinesis 1) | protein interactions | 9055 | 20 | 6 | 16036 | 1726 |
PLK1,KIF23,CENPE,CCNB1,CDK1,SH3KBP1 |
| 1.581e-02 | -4.15 | CASP8AP2 (caspase 8 associated protein 2) | protein interactions | 9994 | 20 | 6 | 16036 | 1726 |
TRIM21,MX1,BCL2L1,SP100,CALM1,FAS |
| 1.581e-02 | -4.15 | RNF34 (ring finger protein 34, E3 ubiquitin protein ligase) | protein interactions | 80196 | 20 | 6 | 16036 | 1726 |
PHF7,APPBP2,SH3KBP1,CASP9,CDC20,TP53 |
| 1.581e-02 | -4.15 | ANKRD44 (ankyrin repeat domain 44) | protein interactions | 91526 | 20 | 6 | 16036 | 1726 |
PLK1,CDKN2C,NOTCH3,PLK2,PPP6R1,WWP2 |
| 1.581e-02 | -4.15 | Mis12 (MIS12 homolog (yeast)) | protein interactions | 67139 | 20 | 6 | 16036 | 1726 |
BUB1,NUF2,ZWINT,SPC25,CYR61,NDC80 |
| 1.589e-02 | -4.14 | polysaccharide metabolic process | biological process | GO:0005976 | 81 | 15 | 16441 | 1675 |
CALM2,PGM1,GAA,B3GNT2,PRKAG2,PPP1R2,UGP2,AKT1,IL6ST,CALM1,CALM3,PGM2L1,NANS,PHKA2,GLT8D2 |
| 1.591e-02 | -4.14 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 161 | 25 | 17758 | 1761 |
MX1,LTBP1,USP18,XYLT1,NDRG2,PRKAR2B,DUSP4,IFIT3,HOXB2,IL6ST,HOXA9,ITGA7,IL31RA,OPN3,NRG1,IFIT1,OAS3,GEM,CMPK2,RAB27B,C12orf75,AHR,IFI6,DENND5B,LAMP3 |
| 1.595e-02 | -4.14 | sulfate activation for sulfonation | BIOCYC pathways | HUMAN_PWY-5340 | 2 | 2 | 907 | 115 |
PAPSS2,PAPSS1 |
| 1.595e-02 | -4.14 | L-lysine degradation XI (mammalian) | BIOCYC pathways | META_LYSINE-DEG1-PWY | 2 | 2 | 907 | 115 |
ALDH7A1,AASS |
| 1.595e-02 | -4.14 | sulfate activation for sulfonation | BIOCYC pathways | META_PWY-5340 | 2 | 2 | 907 | 115 |
PAPSS2,PAPSS1 |
| 1.595e-02 | -4.14 | gamma-glutamyl cycle | BIOCYC pathways | META_PWY-4041 | 2 | 2 | 907 | 115 |
GCLM,GCLC |
| 1.595e-02 | -4.14 | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | BIOCYC pathways | HUMAN_PWY-6138 | 2 | 2 | 907 | 115 |
CMAS,NANS |
| 1.595e-02 | -4.14 | lysine degradation I (saccharopine pathway) | BIOCYC pathways | HUMAN_LYSINE-DEG1-PWY | 2 | 2 | 907 | 115 |
ALDH7A1,AASS |
| 1.600e-02 | -4.14 | BIOCARTA_GPCR_PATHWAY | MSigDB lists | BIOCARTA_GPCR_PATHWAY | 34 | 8 | 17758 | 1761 |
GNAS,CALM2,PLCG1,CALM1,CALM3,PRKAR2B,ELK1,FOS |
| 1.600e-02 | -4.14 | GNF2_PCAF | MSigDB lists | GNF2_PCAF | 34 | 8 | 17758 | 1761 |
MARCH8,FECH,CA2,ERMAP,FBXO9,EIF2AK1,SPTB,TRAK2 |
| 1.600e-02 | -4.14 | GTPASE_BINDING | MSigDB lists | GTPASE_BINDING | 34 | 8 | 17758 | 1761 |
DOCK4,RALBP1,RANBP1,FGD6,RANBP9,ABCA1,RASA1,FGD1 |
| 1.600e-02 | -4.14 | YAGI_AML_RELAPSE_PROGNOSIS | MSigDB lists | YAGI_AML_RELAPSE_PROGNOSIS | 34 | 8 | 17758 | 1761 |
APLP2,ATP6V0B,TYMP,NFKBIA,VAT1,NPC2,CLIP2,LBR |
| 1.600e-02 | -4.14 | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | MSigDB lists | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | 34 | 8 | 17758 | 1761 |
CCND1,CD99,SORT1,NUAK1,NGFRAP1,DPYSL2,PKP2,ATP13A2 |
| 1.600e-02 | -4.14 | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | MSigDB lists | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | 34 | 8 | 17758 | 1761 |
CDK17,UAP1,ECE1,FHL1,HMGA1,ITPKA,ITPR3,PHLDA1 |
| 1.600e-02 | -4.14 | PLASARI_TGFB1_TARGETS_1HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_1HR_UP | 34 | 8 | 17758 | 1761 |
HES1,CYR61,NR4A1,SPATA13,ZMIZ1,SLC20A1,CDK5R1,IER3 |
| 1.604e-02 | -4.13 | HRAS (Harvey rat sarcoma viral oncogene homolog) | protein interactions | 3265 | 105 | 19 | 16036 | 1726 |
FAM213B,RASGRF1,PIK3R1,GRIN1,TP53,GPSM2,ERBB2IP,ICMT,PDGFB,RHEB,RASA1,SH3KBP1,PIK3CA,GRIN2D,DAB2IP,PIK3CD,TIAM1,SPRY2,RASGRP1 |
| 1.605e-02 | -4.13 | regulation of canonical Wnt signaling pathway | biological process | GO:0060828 | 229 | 34 | 16441 | 1675 |
CTHRC1,LGR4,PSME2,SOX9,LRP4,PSMD10,AES,PSME1,APC2,KREMEN1,FZD6,PPP2R3A,PSMD1,RNF220,DACT1,DAB2IP,DIXDC1,WNT3A,DVL2,PSMB4,ASPM,AMER1,PRICKLE1,NPHP3,PSMA4,ANKRD10,GPRC5B,ANKRD6,FGFR2,NKD1,TBX18,LRRK1,FZD5,RNF146 |
| 1.605e-02 | -4.13 | liposarcoma | COSMIC cancer mutations | liposarcoma | 114 | 19 | 17775 | 1757 |
SPEF2,SMARCA2,ARAP3,AKT1,GNE,TP53,ERBB2,VARS2,IDH1,SPTB,GNAS,SS18,CDH1,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 1.606e-02 | -4.13 | regulation of anion transmembrane transport | biological process | GO:1903959 | 27 | 7 | 16441 | 1675 |
IRS2,TCAF1,CLCN3,ANO9,AKT1,ANO1,ANO6 |
| 1.606e-02 | -4.13 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045736 | 27 | 7 | 16441 | 1675 |
PLK1,TFAP4,CDKN1B,CDK5RAP1,CASP3,UBE2C,PTEN |
| 1.616e-02 | -4.13 | V$EN1_01 | MSigDB lists | V$EN1_01 | 106 | 18 | 17758 | 1761 |
CD55,GRHL2,SAT1,MORF4L2,SAV1,FNDC3A,NEO1,KDM4D,FOXP2,PEX2,MITF,SIPA1L1,NR4A3,NRG1,SH3BGRL2,FHL1,MAP3K5,OSR1 |
| 1.616e-02 | -4.13 | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | MSigDB lists | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | 106 | 18 | 17758 | 1761 |
PLEKHA6,FBXL16,GRHL2,SERTAD4,FXYD3,MTL5,RET,ERBB2,COX6C,EPCAM,EPN3,AP1M2,SLC25A4,CDH1,NAT1,SPINT2,ACOX2,MAL2 |
| 1.617e-02 | -4.12 | CTATGCA,MIR-153 | MSigDB lists | CTATGCA,MIR-153 | 202 | 30 | 17758 | 1761 |
LAMP1,DPYSL5,SUN2,EPHA4,PIK3R1,FURIN,MIER3,TESK2,GALNT7,TP53INP2,TTYH3,SIX4,RASA1,DCP2,ZFYVE9,APLP2,MFAP3L,SLC4A4,ZNRF2,FGFR2,SLC9A6,SGK3,SH3BP4,KLF5,RNF26,CITED2,GLCCI1,TPCN1,CKAP4,TRAK2 |
| 1.617e-02 | -4.12 | V$AHR_Q5 | MSigDB lists | V$AHR_Q5 | 202 | 30 | 17758 | 1761 |
BIN1,ATL1,RHOA,MOSPD2,NR3C1,CBX6,MPP5,RAB6A,SNX12,PRDX4,IRF2BPL,B3GALNT1,ONECUT1,DAZAP1,CYP1A1,ACADSB,CDK16,BHLHE41,FUT8,FOSB,SPINT2,SRR,TUBG1,AGFG2,CDKN1B,NRG1,BTBD3,NRGN,FGD1,CYP1B1 |
| 1.617e-02 | -4.12 | FH (fumarate hydratase) | protein interactions | 2271 | 77 | 15 | 16036 | 1726 |
PGM1,DAZAP1,ALDH5A1,GNPDA1,CALD1,PAPSS1,HEXB,EZR,CAB39,AHCY,GOT1,NANS,PIM1,ISOC2,H2AFV |
| 1.618e-02 | -4.12 | skin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-adnexal_tumour-malignant_adnexal_tumour | 16 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | soft_tissue-fat-liposarcoma-pleomorphic | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-pleomorphic | 16 | 5 | 17775 | 1757 |
CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | serrated_polyp | COSMIC cancer mutations | serrated_polyp | 16 | 5 | 17775 | 1757 |
GNAS,PTEN,PIK3R1,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | large_intestine-colon-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-colon-serrated_polyp-serrated_adenoma | 16 | 5 | 17775 | 1757 |
GNAS,PTEN,PIK3R1,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | neurocristic_hamartoma | COSMIC cancer mutations | neurocristic_hamartoma | 16 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | 16 | 5 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,TP53 |
| 1.618e-02 | -4.12 | bone-mandible-other-ameloblastoma | COSMIC cancer mutations | bone-mandible-other-ameloblastoma | 16 | 5 | 17775 | 1757 |
ERBB2,JAK3,FGFR2,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | skin-leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-leg-adnexal_tumour-malignant_adnexal_tumour | 16 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | skin-other-neurocristic_hamartoma | COSMIC cancer mutations | skin-other-neurocristic_hamartoma | 16 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | tubular | COSMIC cancer mutations | tubular | 16 | 5 | 17775 | 1757 |
GNAS,PTEN,PIK3R1,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | serrated_adenoma | COSMIC cancer mutations | serrated_adenoma | 16 | 5 | 17775 | 1757 |
GNAS,PTEN,PIK3R1,PIK3CA,TP53 |
| 1.618e-02 | -4.12 | ameloblastoma | COSMIC cancer mutations | ameloblastoma | 16 | 5 | 17775 | 1757 |
ERBB2,JAK3,FGFR2,PIK3CA,TP53 |
| 1.619e-02 | -4.12 | V$OCT1_Q5_01 | MSigDB lists | V$OCT1_Q5_01 | 252 | 36 | 17758 | 1761 |
SCOC,THRA,TSC22D3,MRAS,MGAT5B,HPCAL4,PPP2R3A,FOXP2,ADORA1,PTEN,CYR61,DPYSL2,LHX6,ATP8B1,CNNM4,TSPAN13,PDE4D,MANF,FZD4,SH3BGRL,SERTAD4,STAT4,KIF13A,LDB2,TP53INP2,DPYSL3,NIN,CXXC4,GPRC5B,FAM117A,TMOD2,SP6,CEP41,ARF6,TLL2,DIS3L |
| 1.619e-02 | -4.12 | V$AP1_Q4_01 | MSigDB lists | V$AP1_Q4_01 | 252 | 36 | 17758 | 1761 |
CMAS,CAMKK1,CALB2,ETV5,FBXO2,NDRG2,FAM81A,DHRS3,SRPX2,LTBP3,ZNF385B,PSMD1,FAM46A,IGSF9,SHC3,SLC16A6,ADAM15,ABCD1,NTN4,MYH14,TINAGL1,SNX10,ELK3,MCTP1,RGAG1,TMEM151A,COL7A1,ATP1B1,C15orf39,ZFAND5,TYSND1,PRX,MAP2,COBL,TOB1,COL16A1 |
| 1.628e-02 | -4.12 | antigen processing and presentation | biological process | GO:0019882 | 213 | 32 | 16441 | 1675 |
HLA-E,PSME2,HLA-F,TAP1,PDIA3,KIF23,PSMD10,PSME1,RAB6A,BCAP31,HLA-A,MARCH8,PSMD1,AP1M2,HLA-C,LGMN,ERAP2,SEC23A,RAB3B,SEC61B,PSMB4,UBE2A,KIF11,PSMA4,CTSL,DCTN6,TAPBP,HLA-B,CTSV,ERAP1,CENPE,ITGAV |
| 1.629e-02 | -4.12 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 615 | 78 | 17570 | 1756 |
LAMP1,SLC2A4,NF2,TRIP10,ARFGEF1,NDRG2,ERBB2,HDAC6,PRKACA,APC2,TRIM68,NCS1,RAB15,CDH1,CTGF,WDR44,CABP1,OSBPL3,DLG1,AKR1B1,ECE1,TSPAN1,PACSIN1,MYRIP,S100A13,MX1,SEC23A,CAPN6,S100A4,CDC20,EZR,SLC11A2,PRKAR2B,PRKRA,OPTN,DNM1L,STK26,ATP7B,ABCA1,COBL,SORT1,PINK1,NFKBIE,RASA2,ATP9A,HERC5,LMNA,M6PR,KIF5B,ITGA3,MLPH,RNF128,CST3,PLEKHF1,ABCD1,PIKFYVE,S100A6,CKAP4,RAB3B,RAPGEF2,AMFR,PIK3R1,MAPK8IP1,CDK5R1,GNAS,EPN3,GALNT3,CSF1,DBI,AURKA,MAL2,PLD1,GPER1,FZD5,NDFIP1,NRBP1,PTGES,TMEM173 |
| 1.632e-02 | -4.12 | ENO2 (enolase 2 (gamma, neuronal)) | protein interactions | 2026 | 84 | 16 | 16036 | 1726 |
SIGIRR,TXN,AKT1,CUL4B,HABP4,ASB9,EZR,EFHD2,PLS3,RCN1,PTEN,AKR1B1,TAGLN2,UBE2C,GPX4,CTH |
| 1.635e-02 | -4.11 | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | 372 | 50 | 17758 | 1761 |
DDX58,NKX3-1,KLK10,TRIP10,CAST,HAL,SDC4,HERC5,IL18,OSR2,BCL2L1,SNN,KREMEN1,TNFSF9,ELF3,IER3,NKAIN3,FOXP2,ANKS6,ITGB8,DRAM1,MAPK11,IFIT1,OAS3,ARL4D,ATP2B1,EPB41L5,SPEF2,RAB3B,CD55,CAPN6,FZD4,PLAUR,USP18,RAPGEF2,LITAF,IFIT3,RNF19B,TP53INP2,GPLD1,BHLHB9,MFSD2A,AGBL5,KLF5,IRF7,HS3ST3B1,DRP2,IFIH1,MAFF,COBL |
| 1.638e-02 | -4.11 | MODULE_357 | MSigDB lists | MODULE_357 | 76 | 14 | 17758 | 1761 |
KLK10,KLK5,LMTK3,CA2,KLHL13,FXYD3,ITGA6,ALDH1A3,CDH3,COL7A1,PPP1R14C,F2RL1,S100A2,EFNB1 |
| 1.639e-02 | -4.11 | dDENN_dom | interpro domains | IPR005112 | 16 | 5 | 18293 | 1814 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.639e-02 | -4.11 | RasGAP_dom | interpro domains | IPR001936 | 16 | 5 | 18293 | 1814 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 1.639e-02 | -4.11 | Cytidine_deaminase-like | interpro domains | IPR016193 | 16 | 5 | 18293 | 1814 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 1.639e-02 | -4.11 | Sulfatase_CS | interpro domains | IPR024607 | 16 | 5 | 18293 | 1814 |
GNS,ARSB,ARSG,GALNS,SULF2 |
| 1.639e-02 | -4.11 | uDENN_dom | interpro domains | IPR005113 | 16 | 5 | 18293 | 1814 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.639e-02 | -4.11 | DENN_dom | interpro domains | IPR001194 | 16 | 5 | 18293 | 1814 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.639e-02 | -4.11 | CMP_dCMP_Zn-bd | interpro domains | IPR002125 | 16 | 5 | 18293 | 1814 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 1.639e-02 | -4.11 | DASU_IL6_SIGNALING_SCAR_DN | MSigDB lists | DASU_IL6_SIGNALING_SCAR_DN | 16 | 5 | 17758 | 1761 |
TMBIM6,SGK1,LOXL2,CTGF,CYR61 |
| 1.639e-02 | -4.11 | MICROTUBULE_MOTOR_ACTIVITY | MSigDB lists | MICROTUBULE_MOTOR_ACTIVITY | 16 | 5 | 17758 | 1761 |
KIF23,KIF5B,CENPE,KIF11,APPBP2 |
| 1.639e-02 | -4.11 | FINETTI_BREAST_CANCER_KINOME_GREEN | MSigDB lists | FINETTI_BREAST_CANCER_KINOME_GREEN | 16 | 5 | 17758 | 1761 |
PRKCQ,MLKL,JAK3,STK17B,SYK |
| 1.639e-02 | -4.11 | BIOCARTA_BCELLSURVIVAL_PATHWAY | MSigDB lists | BIOCARTA_BCELLSURVIVAL_PATHWAY | 16 | 5 | 17758 | 1761 |
CASP3,AKT1,FOS,PIK3R1,PIK3CA |
| 1.639e-02 | -4.11 | MACLACHLAN_BRCA1_TARGETS_DN | MSigDB lists | MACLACHLAN_BRCA1_TARGETS_DN | 16 | 5 | 17758 | 1761 |
CCNB1,COL16A1,CD9,SEMA3B,BAX |
| 1.639e-02 | -4.11 | REACTOME_RAP1_SIGNALLING | MSigDB lists | REACTOME_RAP1_SIGNALLING | 16 | 5 | 17758 | 1761 |
RAP1GAP,PRKACA,RASGRP1,PRKG1,RASGRP2 |
| 1.639e-02 | -4.11 | GOUYER_TATI_TARGETS_DN | MSigDB lists | GOUYER_TATI_TARGETS_DN | 16 | 5 | 17758 | 1761 |
IGFBP2,S100A4,BMP7,A4GALT,MAPK12 |
| 1.639e-02 | -4.11 | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | 16 | 5 | 17758 | 1761 |
LAMP2,HDAC1,GSTP1,ITGA6,NMI |
| 1.639e-02 | -4.11 | MODULE_315 | MSigDB lists | MODULE_315 | 16 | 5 | 17758 | 1761 |
KIF23,BUB1,CENPE,KIF11,CDC20 |
| 1.639e-02 | -4.11 | COENZYME_BINDING | MSigDB lists | COENZYME_BINDING | 16 | 5 | 17758 | 1761 |
ALDH6A1,SPR,AIFM2,GCLC,ACOT7 |
| 1.639e-02 | -4.11 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | MSigDB lists | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | 16 | 5 | 17758 | 1761 |
CALM2,CALM3,PGM1,PHKA2,CALM1 |
| 1.639e-02 | -4.11 | V$PAX5_02 | MSigDB lists | V$PAX5_02 | 16 | 5 | 17758 | 1761 |
PIM1,CORO2A,FAM13B,RASGRP2,ARFGEF1 |
| 1.641e-02 | -4.11 | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDM_DN | 194 | 29 | 17758 | 1761 |
WASF3,ARHGEF3,B3GNT2,SLC37A1,FIGNL1,CPT2,C1GALT1C1,TFAP2C,TEX2,CARD10,FRMD4B,KLHL2,IRS2,ETS2,RBL1,RND3,SLC16A6,CSF1,NFKBIA,SECTM1,ITPR1,BCL6,TAGLN2,SPCS3,NCAM1,PTPRE,NDUFA12,MAFF,RASGRP1 |
| 1.641e-02 | -4.11 | GSE17721_CTRL_VS_POLYIC_6H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_6H_BMDM_DN | 194 | 29 | 17758 | 1761 |
GCA,LZTFL1,ARHGEF3,GRHL2,CRYM,FRMD6,C3orf52,NUB1,PARP4,EPHA1,CRABP2,STEAP1,APPBP2,RAD23A,ELF3,MAPKAPK2,AP1AR,BFSP1,PPP2R5A,ETS2,IGSF9,FRYL,TBX18,MRPS28,ARF6,ICOSLG,PTGES,ISOC1,EHD1 |
| 1.641e-02 | -4.11 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_UP | 194 | 29 | 17758 | 1761 |
RUNX2,IL15,PSME2,MPP1,FURIN,PDK3,FNDC3A,ASB13,BBS2,ARF4,CHPF,ENDOD1,HLA-B,CNTRL,CTSC,RND3,LHX6,MITF,CDKN1B,HDAC1,SNX16,SP6,RFX5,ATP1B3,ITGAV,GLA,TIPARP,IFIH1,MCCC2 |
| 1.641e-02 | -4.11 | GSE17721_0.5H_VS_24H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDM_DN | 194 | 29 | 17758 | 1761 |
PLA2G4A,LAMP2,ENPP4,GCLM,LZTFL1,ARHGEF3,TNIP1,HLA-E,USP18,CD82,PPFIBP2,TAP1,PKP2,RAD17,ANTXR1,RNF19B,REPS1,CYB5A,SUSD2,HLA-B,LMO4,FAM114A1,FAM20B,TRIM21,MDFIC,SNX10,MYLIP,ABCA1,CYP1B1 |
| 1.641e-02 | -4.11 | GSE20715_WT_VS_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_LUNG_UP | 194 | 29 | 17758 | 1761 |
SYPL1,DYNLRB1,FBLN5,PARP12,ARMCX3,EPAS1,PIK3R1,FAM198B,IFIT3,ANO1,TMCC3,CDKN2C,PDGFA,BTG3,JAK1,CTGF,GPRC5B,TWSG1,RND3,NPNT,RRBP1,RANBP1,CD9,GOT1,TACSTD2,SERPINB1,HSPB1,ALDH3A2,SULF2 |
| 1.641e-02 | -4.11 | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | MSigDB lists | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | 194 | 29 | 17758 | 1761 |
MRPS33,B3GNT2,EPAS1,CD63,PSME2,HLA-E,BCL9,STAT4,TAP1,BTN3A2,NDUFA4,PSME1,IFIT3,COX6C,ANTXR1,PHLDA1,HLA-A,HLA-B,C19orf66,PEX2,NMI,TRIM21,HLA-C,IFIH1,IFI6,MYL12B,COBL,JARID2,CKS2 |
| 1.641e-02 | -4.11 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | 194 | 29 | 17758 | 1761 |
SGCE,SLC25A24,FLYWCH2,CAST,RUSC2,TSC22D3,CASP9,MPP5,MAP3K6,MECOM,AKIRIN1,C16orf74,WEE1,GPRC5B,TWSG1,NPNT,STIM1,METTL7A,AXL,TWIST1,CRY2,TAGLN2,PER3,NDE1,RAP1GAP,SLC25A38,NDFIP1,HSPB1,SEMA3B |
| 1.641e-02 | -4.11 | GSE8515_IL1_VS_IL6_4H_STIM_)MAC_UP | MSigDB lists | GSE8515_IL1_VS_IL6_4H_STIM_)MAC_UP | 194 | 29 | 17758 | 1761 |
PPIF,SLC37A1,TNIP1,RIPK2,TRIP10,STAT4,SEPT6,SDC4,PTGER4,NFE2L1,SNN,CENPN,TNFSF9,CD83,IER3,BTG3,FRY,FAM189A1,SLC16A6,SLC2A6,NFKBIA,RAP2C,KLF5,CD70,RP2,MAFF,RASGRP1,DOCK9,EHD1 |
| 1.645e-02 | -4.11 | glycolipid metabolic process | biological process | GO:0006664 | 111 | 19 | 16441 | 1675 |
UGT8,PLAUR,HEXB,ASAH1,ARSK,CPTP,GPLD1,B4GALNT1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,CTSA,GLA,ARSB,ST3GAL1,NAGA,GM2A |
| 1.645e-02 | -4.11 | formation of primary germ layer | biological process | GO:0001704 | 111 | 19 | 16441 | 1675 |
EPB41L5,TNRC6C,NF2,COL7A1,DUSP4,PRKACA,COL12A1,MMP15,ITGA3,ETS2,FGFR2,TWSG1,BMP7,ITGA7,COL6A1,ELF5,NR4A3,ITGAV,WNT3A |
| 1.647e-02 | -4.11 | insulin binding | molecular function | GO:0043559 | 6 | 3 | 16491 | 1673 |
IDE,IGF1R,PIK3R1 |
| 1.647e-02 | -4.11 | phosphatidylinositol trisphosphate phosphatase activity | molecular function | GO:0034594 | 6 | 3 | 16491 | 1673 |
PTEN,INPP5D,INPP4B |
| 1.647e-02 | -4.11 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | molecular function | GO:0016812 | 6 | 3 | 16491 | 1673 |
OPLAH,AMDHD1,DPYSL2 |
| 1.648e-02 | -4.11 | SPTLC2 (serine palmitoyltransferase, long chain base subunit 2) | protein interactions | 9517 | 10 | 4 | 16036 | 1726 |
NRG1,NOTCH3,SPINT2,BCL6 |
| 1.648e-02 | -4.11 | IFIH1 (interferon induced, with helicase C domain 1) | protein interactions | 64135 | 10 | 4 | 16036 | 1726 |
IDE,PTEN,TSPAN6,NLRC5 |
| 1.648e-02 | -4.11 | IL1A (interleukin 1 alpha) | protein interactions | 3552 | 10 | 4 | 16036 | 1726 |
NFKBIE,S100A13,CAPN1,TP53 |
| 1.648e-02 | -4.11 | ZNRF3 (zinc and ring finger 3) | protein interactions | 84133 | 10 | 4 | 16036 | 1726 |
LGR4,HSPB1,FZD4,DVL2 |
| 1.648e-02 | -4.11 | ABCA3 (ATP binding cassette subfamily A member 3) | protein interactions | 21 | 10 | 4 | 16036 | 1726 |
NRG1,ATP1B3,HLA-E,SPINT2 |
| 1.648e-02 | -4.11 | GAD2 (glutamate decarboxylase 2) | protein interactions | 2572 | 10 | 4 | 16036 | 1726 |
MAL2,TMEM159,PRKACA,GAD1 |
| 1.648e-02 | -4.11 | TSPAN6 (tetraspanin 6) | protein interactions | 7105 | 10 | 4 | 16036 | 1726 |
DDX58,LRIF1,IFIH1,TMEM173 |
| 1.648e-02 | -4.11 | ARL3 (ADP-ribosylation factor like GTPase 3) | protein interactions | 403 | 10 | 4 | 16036 | 1726 |
TLE1,RP2,LRIF1,TP53 |
| 1.648e-02 | -4.11 | CLCN3 (chloride channel, voltage-sensitive 3) | protein interactions | 1182 | 10 | 4 | 16036 | 1726 |
CLCN3,LGALS3,HSPB1,LYPD3 |
| 1.652e-02 | -4.10 | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | MSigDB lists | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 91 | 16 | 17758 | 1761 |
PLA2G4A,WASF3,AKT1,INPP5D,PIK3R1,PLCG1,DNM1L,LIMK1,PLCG2,PIK3CA,PIK3CD,PLD1,ARF6,ARPC2,PIKFYVE,SYK |
| 1.652e-02 | -4.10 | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN | MSigDB lists | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN | 91 | 16 | 17758 | 1761 |
EXPH5,PQLC3,ALDH6A1,CDKN1C,AMFR,NENF,SPR,PDIK1L,EPS8L2,PRX,GNB5,WFS1,RYK,CRY2,SLC27A1,SLC16A5 |
| 1.652e-02 | -4.10 | chondroitin sulfate proteoglycan metabolic process | biological process | GO:0050654 | 60 | 12 | 16441 | 1675 |
B3GALT6,CHSY3,HSPG2,XYLT2,IMPAD1,SDC4,XYLT1,HEXB,DSE,ARSB,SDC1,CHPF |
| 1.652e-02 | -4.10 | embryonic digit morphogenesis | biological process | GO:0042733 | 60 | 12 | 16441 | 1675 |
GRHL2,IMPAD1,LRP4,TRAF3IP1,BAX,RAB23,HDAC1,TWIST1,OSR2,ECE1,OSR1,FZD6 |
| 1.656e-02 | -4.10 | CBL (Cbl proto-oncogene, E3 ubiquitin protein ligase) | protein interactions | 867 | 233 | 36 | 16036 | 1726 |
SCN5A,SORBS1,INPP5D,IQGAP1,UBASH3B,RET,ERBB2,SH3KBP1,IGF1R,PTEN,SNX18,PIK3CA,TRIM21,OSTF1,NOTCH3,SPRY2,SYK,FRS3,TRIM8,ITCH,PIK3R1,CALM1,PRKCQ,YES1,CD40,BCAR1,PLCG1,FGFR2,CSF1,CORO1C,AXL,LRIG1,ITGAV,F2RL1,CAPN1,CD33 |
| 1.656e-02 | -4.10 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | 114 | 19 | 17758 | 1761 |
SCOC,ZC3H11A,NUB1,LITAF,KIF1C,GLO1,F11R,GGH,ZNF275,PITX2,RCN1,DCTN6,PTPRF,DDOST,CTSC,CST3,DBI,F2R,MYO5A |
| 1.656e-02 | -4.10 | V$USF_01 | MSigDB lists | V$USF_01 | 244 | 35 | 17758 | 1761 |
LAMP1,ALDH6A1,HOXB7,FAM134A,TESK2,MORF4L2,PKN1,VPS26A,TFAP4,BHLHE41,PLCG2,FAM13B,RANBP1,BAX,ANKRD12,MANF,ARMCX6,DVL2,SIRT1,PHF20L1,HPS3,PLEKHA6,LONRF3,OGDHL,CBX6,GNAS,TIMM8A,HNRNPH2,KBTBD2,HOXA9,GLA,C1orf43,RARG,RAB3IL1,RNF146 |
| 1.658e-02 | -4.10 | tonsil | COSMIC cancer mutations | tonsil | 138 | 22 | 17775 | 1757 |
KIF20A,AKT1,GUSB,MACC1,OGDHL,TP53,ERBB2,TGFBR1,KIF13A,ITPR2,ZFAND5,NIN,CCND1,ARHGEF10L,BTG3,TAPBP,MUC16,FAT4,PTEN,PIK3CA,FHL1,COL16A1 |
| 1.662e-02 | -4.10 | HDASUPER | prints domains | PR01270 | 11 | 4 | 4759 | 462 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.662e-02 | -4.10 | FRIZZLED | prints domains | PR00489 | 11 | 4 | 4759 | 462 |
FZD5,FZD4,FZD7,FZD6 |
| 1.662e-02 | -4.10 | PAPAIN | prints domains | PR00705 | 11 | 4 | 4759 | 462 |
CTSL,CTSZ,CTSC,CTSV |
| 1.662e-02 | -4.10 | ALADIPTASE | prints domains | PR00756 | 11 | 4 | 4759 | 462 |
ERAP1,RNPEP,LTA4H,ERAP2 |
| 1.663e-02 | -4.10 | GSE17721_CTRL_VS_POLYIC_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDM_UP | 186 | 28 | 17758 | 1761 |
SYPL1,GCLM,BCAM,MBP,FAM134A,TESK2,ARHGDIB,MRAS,RAD17,ANLN,SEPP1,SESN1,LTBP3,BCAP31,CYP4F3,NUCB1,RPL12,TIMM8A,GDE1,LIMK1,PRPS2,OPN3,ADAM15,MDH1,CTSA,TECR,MPHOSPH9,MED22 |
| 1.663e-02 | -4.10 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP | 186 | 28 | 17758 | 1761 |
ENPP4,DOCK4,BIN1,ARAP2,CHCHD7,PTPRU,CORO2A,TSC22D3,PPFIBP2,NRG2,STEAP1,ELF3,CNTNAP1,CYP1A1,SP100,NR1D2,COL13A1,CYP4F11,KBTBD2,ADCK2,ECE1,RAB27B,MAST4,L1CAM,SLC16A5,RASGRP1,XKR8,WBP5 |
| 1.663e-02 | -4.10 | GSE10325_CD4_TCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_UP | 186 | 28 | 17758 | 1761 |
FBLN5,ENO2,SLC39A8,STAT4,ITGA6,SYNE2,PIK3R1,ARL4C,TCF7,PRKCQ,NUCB2,DHRS3,LTBP3,DENND2D,OPTN,TMEM63A,AMZ2,PLCG1,MGAT4A,BDH1,LRIG1,INPP4B,FAM102A,PIM1,MYBL1,MAST4,TBC1D4,DOCK9 |
| 1.666e-02 | -4.09 | regulation of cilium movement involved in cell motility | biological process | GO:0060295 | 6 | 3 | 16441 | 1675 |
CFAP20,BBS2,CCSAP |
| 1.666e-02 | -4.09 | negative regulation of striated muscle contraction | biological process | GO:0045988 | 6 | 3 | 16441 | 1675 |
PDE5A,ADORA1,ADRBK1 |
| 1.666e-02 | -4.09 | negative regulation of anion transmembrane transport | biological process | GO:1903960 | 6 | 3 | 16441 | 1675 |
IRS2,ANO9,AKT1 |
| 1.666e-02 | -4.09 | ectodermal cell differentiation | biological process | GO:0010668 | 6 | 3 | 16441 | 1675 |
ETS2,ITGA6,ELF5 |
| 1.666e-02 | -4.09 | paranodal junction assembly | biological process | GO:0030913 | 6 | 3 | 16441 | 1675 |
CNTNAP1,UGT8,CD9 |
| 1.666e-02 | -4.09 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045869 | 6 | 3 | 16441 | 1675 |
APOBEC3H,APOBEC3D,APOBEC3G |
| 1.666e-02 | -4.09 | regulation of antimicrobial peptide production | biological process | GO:0002784 | 6 | 3 | 16441 | 1675 |
KLK7,KLK5,NOD2 |
| 1.666e-02 | -4.09 | positive regulation of antibacterial peptide production | biological process | GO:0002803 | 6 | 3 | 16441 | 1675 |
KLK7,KLK5,NOD2 |
| 1.666e-02 | -4.09 | positive regulation of antimicrobial peptide production | biological process | GO:0002225 | 6 | 3 | 16441 | 1675 |
KLK7,KLK5,NOD2 |
| 1.666e-02 | -4.09 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GO:1901620 | 6 | 3 | 16441 | 1675 |
PRKACA,TRAF3IP1,GPR161 |
| 1.666e-02 | -4.09 | regulation of cilium-dependent cell motility | biological process | GO:1902019 | 6 | 3 | 16441 | 1675 |
CFAP20,BBS2,CCSAP |
| 1.666e-02 | -4.09 | positive regulation of cell aging | biological process | GO:0090343 | 6 | 3 | 16441 | 1675 |
SIRT1,HMGA1,LMNA |
| 1.666e-02 | -4.09 | negative regulation of cholesterol storage | biological process | GO:0010887 | 6 | 3 | 16441 | 1675 |
ABCA1,ABCG1,PPARA |
| 1.666e-02 | -4.09 | regulation of antibacterial peptide production | biological process | GO:0002786 | 6 | 3 | 16441 | 1675 |
KLK7,KLK5,NOD2 |
| 1.666e-02 | -4.09 | regulation of cilium beat frequency involved in ciliary motility | biological process | GO:0060296 | 6 | 3 | 16441 | 1675 |
CFAP20,BBS2,CCSAP |
| 1.666e-02 | -4.09 | activation-induced cell death of T cells | biological process | GO:0006924 | 6 | 3 | 16441 | 1675 |
AKT1,SIVA1,FAS |
| 1.666e-02 | -4.09 | renal interstitial fibroblast development | biological process | GO:0072141 | 6 | 3 | 16441 | 1675 |
HES1,OSR1,PDGFB |
| 1.666e-02 | -4.09 | cytoplasmic pattern recognition receptor signaling pathway in response to virus | biological process | GO:0039528 | 6 | 3 | 16441 | 1675 |
DDX58,IRF7,IFIH1 |
| 1.666e-02 | -4.09 | DNA cytosine deamination | biological process | GO:0070383 | 6 | 3 | 16441 | 1675 |
APOBEC3H,APOBEC3D,APOBEC3G |
| 1.666e-02 | -4.09 | positive regulation of protein glycosylation | biological process | GO:0060050 | 6 | 3 | 16441 | 1675 |
IL15,ARFGEF1,CHP1 |
| 1.671e-02 | -4.09 | RYDR_ITPR | pfam domains | PF01365 | 6 | 3 | 16629 | 1696 |
ITPR2,ITPR3,ITPR1 |
| 1.671e-02 | -4.09 | Ins145_P3_rec | pfam domains | PF08709 | 6 | 3 | 16629 | 1696 |
ITPR2,ITPR3,ITPR1 |
| 1.671e-02 | -4.09 | FBA | pfam domains | PF04300 | 6 | 3 | 16629 | 1696 |
FBXO6,FBXO27,FBXO2 |
| 1.671e-02 | -4.09 | PET | pfam domains | PF06297 | 6 | 3 | 16629 | 1696 |
PRICKLE1,PRICKLE3,LMCD1 |
| 1.671e-02 | -4.09 | RIH_assoc | pfam domains | PF08454 | 6 | 3 | 16629 | 1696 |
ITPR2,ITPR3,ITPR1 |
| 1.671e-02 | -4.09 | Na_trans_cytopl | pfam domains | PF11933 | 6 | 3 | 16629 | 1696 |
SCN5A,SCN2A,SCN3A |
| 1.676e-02 | -4.09 | endoplasmic reticulum-Golgi intermediate compartment | cellular component | GO:0005793 | 98 | 17 | 17570 | 1756 |
RGMB,CTSZ,COL7A1,MCFD2,NUCB2,BCAP31,STK17B,NUCB1,SERPINA1,CTSC,MYDGF,PIEZO1,LMAN1,PDIA6,GOLGB1,CHP1,KDELR1 |
| 1.679e-02 | -4.09 | Apoptosis | REACTOME pathways | R-HSA-109581 | 160 | 26 | 8202 | 867 |
CASP3,BMF,PSMB4,ADD1,AKT1,PSME2,CASP9,TP53,PSMD10,PRKCQ,PSME1,BCL2L1,PSMA4,BCAP31,LMNA,FAS,DAPK2,PSMD1,CDH1,DNM1L,H1F0,STK26,DAPK1,BAX,UNC5B,OCLN |
| 1.680e-02 | -4.09 | lip | COSMIC cancer mutations | lip | 28 | 7 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53 |
| 1.682e-02 | -4.09 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | 178 | 27 | 17758 | 1761 |
LMO7,BIN1,REC8,FBXL16,KIFC2,ARHGEF11,CKAP2,UBASH3B,TSC22D3,EPHA4,ASAH1,DIAPH2,STMN3,SNN,H1FX,IRS2,FAM111A,PELI2,KLF11,TAGLN2,MARCH2,PDE4D,CITED2,MAFF,TOB1,S100A6,PCSK5 |
| 1.688e-02 | -4.08 | cellular response to steroid hormone stimulus | biological process | GO:0071383 | 142 | 23 | 16441 | 1675 |
THRB,NKX3-1,NR3C1,THRA,NR4A1,CASP9,PPARA,ELK1,FECH,TFAP4,NCOA3,ATP1A1,NR1D2,BMP7,NR4A3,NR4A2,GPER1,KLF9,NR3C2,RARG,NR2C1,NR2C2,PAQR7 |
| 1.694e-02 | -4.08 | V$MYB_Q6 | MSigDB lists | V$MYB_Q6 | 236 | 34 | 17758 | 1761 |
IER5L,LTBP1,CDK17,PPP4R4,SDC1,REPS1,SLC9A7,MDM1,SESN3,PHF7,ADRBK1,SLC16A6,DACT1,FRAS1,TOX2,FAM63A,TRPC1,DLG3,CITED2,DLGAP1,RHOA,TFAP2C,PRICKLE1,TYSND1,GNAS,ONECUT1,ZNF367,WFS1,AGBL5,KLF5,OSR1,RARG,NR3C2,JARID2 |
| 1.695e-02 | -4.08 | - | gene3d domains | 3.40.850.10 | 44 | 10 | 9988 | 1080 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 1.697e-02 | -4.08 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | 69 | 13 | 17758 | 1761 |
CDH1,NGFRAP1,BMP7,TNFRSF12A,ISYNA1,UNC5B,CCNB1,NUCB2,DDR1,UBE2C,MAFF,PROM2,IGDCC4 |
| 1.697e-02 | -4.08 | KEGG_LONG_TERM_POTENTIATION | MSigDB lists | KEGG_LONG_TERM_POTENTIATION | 69 | 13 | 17758 | 1761 |
CALM2,RPS6KA2,RPS6KA1,ITPR1,CALM1,GRIN1,CALM3,GRIN2D,ITPR2,ITPR3,PLCB2,PRKACA,GRM5 |
| 1.697e-02 | -4.08 | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | 69 | 13 | 17758 | 1761 |
PDGFA,HLA-B,TIMP3,IL15RA,AKT1,IFITM3,CASP9,PPARA,TP53,IL18,HLA-C,ETV4,FAS |
| 1.697e-02 | -4.08 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 69 | 13 | 17758 | 1761 |
MAPKAPK2,PRKAA2,PLCG1,RHOA,PTPRJ,AKT1,IQGAP1,PIK3R1,PIK3CA,MAPK11,ITGAV,PRKACA,GAB1 |
| 1.699e-02 | -4.08 | axon | cellular component | GO:0030424 | 370 | 50 | 17570 | 1756 |
BIN1,ANXA3,PINK1,LMTK3,IQGAP1,CALB2,EPHA4,RET,GABRG2,CNTNAP2,HDAC6,NCS1,NOV,ADORA1,CA2,IGSF9,DPYSL2,FLRT3,KIF13B,CST3,DLG1,DAB2IP,GOT1,MYH14,SCN2A,PACSIN1,ATL1,CLCN3,MBP,RHOA,SEPT6,CCSAP,GRIN1,STMN3,ELK1,ALCAM,NFIB,DAG1,MAPK8IP1,CDK5R1,CNTNAP1,SYT7,SLC9A6,AURKA,NRG1,GPER1,SEMA3A,NRGN,COBL,L1CAM |
| 1.700e-02 | -4.07 | Fcgamma receptor (FCGR) dependent phagocytosis | REACTOME pathways | R-HSA-2029480 | 86 | 16 | 8202 | 867 |
WASF3,PIK3R1,YES1,ITPR2,NCKAP1,ITPR3,PLCG1,ELMO2,LIMK1,ITPR1,PLCG2,PIK3CA,PLD1,ARPC2,SYK,MYO5A |
| 1.700e-02 | -4.07 | TGGNNNNNNKCCAR_UNKNOWN | MSigDB lists | TGGNNNNNNKCCAR_UNKNOWN | 399 | 53 | 17758 | 1761 |
IER5L,ANXA3,NCKAP5,CTHRC1,SLC25A24,PCOLCE,SLC2A4,DDIT4L,TP53,MORC4,ISYNA1,SDC1,PDGFB,EFNB1,SPTB,H1FX,SH2D4A,CCDC92,FOXP2,ADD3,SCNN1A,RALGPS2,CYR61,WDR44,KCNN4,MGAT4A,VASN,TOX2,GOT1,DAB2IP,TINAGL1,ZNF462,CLCN3,SALL4,PPARA,VWA1,ROR1,ATP1B1,PRKRA,NFIB,PGF,ALDH3B1,ARHGEF19,SWAP70,HOXA9,SETD3,NFKBIA,RAP2C,OVOL1,FHL1,MAP3K5,PRR15,NR2C2 |
| 1.704e-02 | -4.07 | V$TAXCREB_01 | MSigDB lists | V$TAXCREB_01 | 130 | 21 | 17758 | 1761 |
PHF20L1,ARMCX3,PTPRU,DNAJB2,SLC25A5,FOS,TSPAN7,APPBP2,IRF2BPL,LMO4,FOSB,NR4A3,PLK4,OTUB2,CDKN1B,RFX5,TAGLN2,KLF9,GEM,OSR1,MAFF |
| 1.704e-02 | -4.07 | RODWELL_AGING_KIDNEY_DN | MSigDB lists | RODWELL_AGING_KIDNEY_DN | 130 | 21 | 17758 | 1761 |
PRKAA2,CEP70,AASS,GYLTL1B,HDAC6,OAT,TSPAN7,GABARAPL1,SLC25A36,SCML1,GNAS,APLP2,UAP1,BMP7,SRR,ECI2,YOD1,KLF9,GAD1,ISOC1,CTH |
| 1.704e-02 | -4.07 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | 130 | 21 | 17758 | 1761 |
TIMP2,RHOA,PSMB4,SDC4,COL18A1,GLO1,CTSZ,NPC2,GSTP1,PSMA4,LGALS3BP,LMNA,FUCA1,NUCB1,CDH1,CST3,CD9,AKR1B1,GOT1,SERPINB6,TINAGL1 |
| 1.708e-02 | -4.07 | LOPES_METHYLATED_IN_COLON_CANCER_DN | MSigDB lists | LOPES_METHYLATED_IN_COLON_CANCER_DN | 28 | 7 | 17758 | 1761 |
PITX2,THRB,RUNX3,CDKN1C,NR3C1,GSTP1,TFAP2A |
| 1.708e-02 | -4.07 | STANELLE_E2F1_TARGETS | MSigDB lists | STANELLE_E2F1_TARGETS | 28 | 7 | 17758 | 1761 |
CCND1,AURKA,CCNE2,MAP3K5,ENO2,TNFSF9,CD9 |
| 1.708e-02 | -4.07 | AIYAR_COBRA1_TARGETS_DN | MSigDB lists | AIYAR_COBRA1_TARGETS_DN | 28 | 7 | 17758 | 1761 |
CPD,CLDN4,ZNF395,SLC20A1,METTL7A,HSPB1,PRX |
| 1.708e-02 | -4.07 | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | 28 | 7 | 17758 | 1761 |
PBX3,FHL1,SORBS1,CTGF,CYR61,ALCAM,PTGER4 |
| 1.708e-02 | -4.07 | HWANG_PROSTATE_CANCER_MARKERS | MSigDB lists | HWANG_PROSTATE_CANCER_MARKERS | 28 | 7 | 17758 | 1761 |
EZR,TXN,FBLN5,PIM1,WNT3A,LGALS3,PTEN |
| 1.708e-02 | -4.07 | MATZUK_MALE_REPRODUCTION_SERTOLI | MSigDB lists | MATZUK_MALE_REPRODUCTION_SERTOLI | 28 | 7 | 17758 | 1761 |
MAN2A2,CDKN2C,HMGA1,SOX8,SBF1,SLC12A2,B4GALNT1 |
| 1.708e-02 | -4.07 | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | 28 | 7 | 17758 | 1761 |
IRS2,RAB20,EGLN3,SERPINB1,AK7,SAT1,KLF7 |
| 1.708e-02 | -4.07 | TSENG_ADIPOGENIC_POTENTIAL_UP | MSigDB lists | TSENG_ADIPOGENIC_POTENTIAL_UP | 28 | 7 | 17758 | 1761 |
PTPRF,TCF7,COL7A1,FHL1,CRABP2,PRSS23,MAPK12 |
| 1.710e-02 | -4.07 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | 162 | 25 | 17758 | 1761 |
MX1,ANXA3,PLSCR1,ITCH,USP18,C3orf52,OSGIN2,HERC5,IFIT3,HERC6,STX3,TYMP,SP100,LHX6,TOX2,SH3BP4,OVOL1,PGM2L1,TRPC1,IFIT1,FZD5,IFIH1,IFI6,LAMP3,SNX7 |
| 1.712e-02 | -4.07 | COL3A1 (collagen, type III, alpha 1) | protein interactions | 1281 | 15 | 5 | 16036 | 1726 |
PDGFA,PCOLCE,DDR1,PDGFB,CAPN1 |
| 1.712e-02 | -4.07 | GRM1 (glutamate receptor, metabotropic 1) | protein interactions | 2911 | 15 | 5 | 16036 | 1726 |
TRPC1,ADORA1,ADRBK1,ITPR1,OPTN |
| 1.712e-02 | -4.07 | SFR1 (SWI5-dependent homologous recombination repair protein 1) | protein interactions | 119392 | 15 | 5 | 16036 | 1726 |
CEP70,NMI,TRAF3IP1,NDC80,SWI5 |
| 1.712e-02 | -4.07 | MYL9 (myosin light chain 9) | protein interactions | 10398 | 15 | 5 | 16036 | 1726 |
MYH14,HSPB1,MYL12A,TP53,PIP4K2C |
| 1.712e-02 | -4.07 | GLA (galactosidase, alpha) | protein interactions | 2717 | 15 | 5 | 16036 | 1726 |
GNS,ALDH7A1,GLA,FBXO6,CAPN1 |
| 1.712e-02 | -4.07 | MYL12B (myosin light chain 12B) | protein interactions | 103910 | 15 | 5 | 16036 | 1726 |
ARRB1,LGALS3,MYLIP,HSPB1,DAPK1 |
| 1.712e-02 | -4.07 | SELPLG (selectin P ligand) | protein interactions | 6404 | 15 | 5 | 16036 | 1726 |
SELL,TNIP1,SYK,PIK3R1,TPST1 |
| 1.712e-02 | -4.07 | PHKB (phosphorylase kinase, beta) | protein interactions | 5257 | 15 | 5 | 16036 | 1726 |
DOK4,CORO1C,CALM1,DCP2,TP53 |
| 1.713e-02 | -4.07 | KAMMINGA_EZH2_TARGETS | MSigDB lists | KAMMINGA_EZH2_TARGETS | 41 | 9 | 17758 | 1761 |
TOP2A,RBL1,CDCA5,NEK2,AURKA,AHCY,NUSAP1,CCNB2,PRIM1 |
| 1.713e-02 | -4.07 | NAKAMURA_METASTASIS_MODEL_DN | MSigDB lists | NAKAMURA_METASTASIS_MODEL_DN | 41 | 9 | 17758 | 1761 |
TTC8,DDB2,SLCO4A1,RUNX2,CAST,AK4,TMEM120A,SERPINB1,RRAGD |
| 1.713e-02 | -4.07 | MODY_HIPPOCAMPUS_PRENATAL | MSigDB lists | MODY_HIPPOCAMPUS_PRENATAL | 41 | 9 | 17758 | 1761 |
TOP2A,RPL12,H1F0,TP53,H2AFV,MYT1,CCNB2,UBE2C,CKS2 |
| 1.713e-02 | -4.07 | PID_ER_NONGENOMIC_PATHWAY | MSigDB lists | PID_ER_NONGENOMIC_PATHWAY | 41 | 9 | 17758 | 1761 |
RHOA,IGF1R,AKT1,PIK3R1,PIK3CA,MAPK11,BCAR1,PLCB2,GNA11 |
| 1.713e-02 | -4.07 | RIZ_ERYTHROID_DIFFERENTIATION_HBZ | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_HBZ | 41 | 9 | 17758 | 1761 |
PITX2,TSC22D3,FOSB,TFAP2C,NR4A2,HOXB13,BARD1,CBX7,E2F8 |
| 1.713e-02 | -4.07 | Cyclin-like | interpro domains | IPR013763 | 41 | 9 | 18293 | 1814 |
CCNE2,CCNI,CCND1,RBL1,CCNJL,CCNB1,CCNF,CCNB2,CDK5R1 |
| 1.718e-02 | -4.06 | LABBE_TGFB1_TARGETS_UP | MSigDB lists | LABBE_TGFB1_TARGETS_UP | 99 | 17 | 17758 | 1761 |
TGIF1,AASS,CAST,IQGAP1,SAT1,FURIN,LITAF,ITPR2,PDGFB,BEX2,PDGFA,CTGF,CYR61,BMP1,SGK1,CITED2,ABCG1 |
| 1.720e-02 | -4.06 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | ko00532 | 20 | 6 | 6908 | 758 |
B3GALT6,CHSY3,DSE,XYLT2,XYLT1,CHPF |
| 1.720e-02 | -4.06 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | hsa00532 | 20 | 6 | 6908 | 758 |
B3GALT6,CHSY3,DSE,XYLT2,XYLT1,CHPF |
| 1.721e-02 | -4.06 | bronchus | COSMIC cancer mutations | bronchus | 22 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,PTEN,PIK3CA,TP53 |
| 1.721e-02 | -4.06 | skin-buttock-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-buttock-other-atypical_Spitzoid_tumour | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-other-atypical_Spitzoid_tumour | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-face-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-face-benign_melanocytic_nevus-Spitz | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-upper_arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_arm-other-atypical_Spitzoid_tumour | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-arm-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-arm-benign_melanocytic_nevus-Spitz | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-lower_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-lower_leg-benign_melanocytic_nevus-Spitz | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | skin-knee-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-knee-benign_melanocytic_nevus-Spitz | 22 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 1.721e-02 | -4.06 | plasma membrane protein complex | cellular component | GO:0098797 | 510 | 66 | 17570 | 1756 |
CASP3,SORBS1,CACNA2D2,IL13RA1,APC2,CACNB4,ABCD4,CDH1,NPNT,IL6ST,DLG1,ABCA2,KCNS3,CTTN,PDE4D,SCN2A,DLG3,GM2A,SCN3A,SGCE,KCNIP3,ACVR1C,SNTB2,UTRN,ATP1B1,CD40,ALCAM,DAG1,KCNMB4,ATP1A1,ABHD12,KCNK1,CORO1C,TRAF5,SCN5A,ITGA6,HLA-F,HLA-E,LRP4,EPS8,TGFBR1,CNTNAP2,HLA-A,NEO1,SNTA1,ITGB8,ITGA3,KCNN4,CACNA1D,HLA-C,SGCB,SYK,GRIN1,SNTB1,GNA11,FAS,CNTNAP1,GNAS,HLA-B,COL13A1,ITGA7,NETO2,ARRB1,GRIN2D,ATP1B3,ITGAV |
| 1.723e-02 | -4.06 | PURINE_RIBONUCLEOTIDE_BINDING | MSigDB lists | PURINE_RIBONUCLEOTIDE_BINDING | 203 | 30 | 17758 | 1761 |
MX1,PINK1,PEX6,GCLC,SEPT6,ABCG2,TP53,TGFBR1,PIF1,MAP3K6,STK17B,RHEB,DGKE,ABCD4,STK17A,DAPK2,ACVRL1,RND3,ATP7B,STK38,ABCA2,DAPK1,ABCB1,PIM1,GEM,MAP3K5,ARF6,ABCC1,SEPHS1,ABCG1 |
| 1.726e-02 | -4.06 | NRP1 (neuropilin 1) | protein interactions | 8829 | 38 | 9 | 16036 | 1726 |
PGF,TMEM30A,TGFBR1,PLXNA1,SEMA3A,PDGFB,L1CAM,NRP2,SEMA3B |
| 1.727e-02 | -4.06 | haematopoietic_and_lymphoid_tissue-breast-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-breast-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 48 | 10 | 17775 | 1757 |
MAN2A2,MUC16,CELSR2,PLOD2,MAP2,RAPGEF2,TMEM30A,RPN2,RIMS2,PCSK5 |
| 1.728e-02 | -4.06 | FERM_1 | prosite domains | PS00660 | 21 | 6 | 11866 | 1235 |
EPB41L5,EZR,FRMD4A,NF2,EPB41L4A,FARP2 |
| 1.728e-02 | -4.06 | HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5) | protein interactions | 51191 | 26 | 7 | 16036 | 1726 |
PITX2,CCND1,HERC5,CCNB1,STK38,RANBP1,TP53 |
| 1.728e-02 | -4.06 | MIS12 (MIS12 kinetochore complex component) | protein interactions | 79003 | 26 | 7 | 16036 | 1726 |
BUB1,NUF2,ZWINT,SERPINA1,SPC25,MAFF,NDC80 |
| 1.728e-02 | -4.06 | SPTA1 (spectrin, alpha, erythrocytic 1) | protein interactions | 6708 | 26 | 7 | 16036 | 1726 |
EZR,NCOA3,ADD1,SPTB,UBASH3B,SLC9A2,MYBL2 |
| 1.729e-02 | -4.06 | DAGKa | smart domains | SM00045 | 10 | 4 | 9131 | 997 |
DGKH,DGKG,DGKQ,DGKE |
| 1.730e-02 | -4.06 | V$GCM_Q2 | MSigDB lists | V$GCM_Q2 | 228 | 33 | 17758 | 1761 |
BCAM,ARMCX3,THRA,CAST,BLVRB,NRG2,PDGFB,REPS1,SCML1,CDKN2C,AIM1L,APLP2,ADD3,SESN3,IGF1R,CYR61,LHX6,SLC44A1,MITF,EPB41L4B,RASGRF1,TRIM8,PANK1,LYRM1,FBXO9,GNAS,PTPRJ,RBM47,ETS2,KLF12,KLF5,PLD1,PIEZO1 |
| 1.740e-02 | -4.05 | DELASERNA_MYOD_TARGETS_UP | MSigDB lists | DELASERNA_MYOD_TARGETS_UP | 84 | 15 | 17758 | 1761 |
BIN1,ATP1A1,PRSS23,PDLIM3,ANKS1B,CD82,LRP4,HDAC11,PLEKHO1,BCL6,KLF5,SCRIB,PRKAR2B,STK17B,TMCC3 |
| 1.741e-02 | -4.05 | glycoprotein binding | molecular function | GO:0001948 | 97 | 17 | 16491 | 1673 |
ERLEC1,GYLTL1B,FBXO2,ERBB2,FBXO6,SDC1,DAG1,RASA1,CTSL,PTPRF,IDE,ITGA3,SERPINA1,CDH1,MAP2,FBXO27,RGMA |
| 1.741e-02 | -4.05 | - | gene3d domains | 1.10.506.10 | 15 | 5 | 9988 | 1080 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 1.741e-02 | -4.05 | - | gene3d domains | 2.60.40.1180 | 15 | 5 | 9988 | 1080 |
FUCA1,MAN2B2,MAN2A2,GLA,NAGA |
| 1.744e-02 | -4.05 | LEE_LIVER_CANCER_E2F1_UP | MSigDB lists | LEE_LIVER_CANCER_E2F1_UP | 62 | 12 | 17758 | 1761 |
KIAA1462,PLSCR1,ETS2,CD63,USP18,GGH,TAGLN2,NUCB2,CYP39A1,CASP4,LEPR,XDH |
| 1.744e-02 | -4.05 | PID_TRKR_PATHWAY | MSigDB lists | PID_TRKR_PATHWAY | 62 | 12 | 17758 | 1761 |
CCND1,RASGRF1,PLCG1,RHOA,SHC3,PIK3R1,PIK3CA,FAIM,TIAM1,GAB1,RASA1,FRS3 |
| 1.747e-02 | -4.05 | ADHERENS_JUNCTION | MSigDB lists | ADHERENS_JUNCTION | 22 | 6 | 17758 | 1761 |
SORBS1,AIF1L,CDH1,BCAR1,SHROOM2,SHROOM3 |
| 1.747e-02 | -4.05 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE | 22 | 6 | 17758 | 1761 |
CHSY3,B3GALT6,DSE,XYLT2,XYLT1,CHPF |
| 1.747e-02 | -4.05 | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 22 | 6 | 17758 | 1761 |
PIM1,IDH1,ST3GAL1,PLCB2,LBR,IER3 |
| 1.747e-02 | -4.05 | BIOCARTA_CHEMICAL_PATHWAY | MSigDB lists | BIOCARTA_CHEMICAL_PATHWAY | 22 | 6 | 17758 | 1761 |
CASP3,BCL2L1,AKT1,CASP9,TP53,BAX |
| 1.747e-02 | -4.05 | RESPONSE_TO_DRUG | MSigDB lists | RESPONSE_TO_DRUG | 22 | 6 | 17758 | 1761 |
BCAR3,GCLM,ABCC1,ABCG2,ABCB1,ABCA2 |
| 1.747e-02 | -4.05 | EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 22 | 6 | 17758 | 1761 |
ERBB2IP,REPS2,BCAR1,SHC3,GAB1,EPS8 |
| 1.747e-02 | -4.05 | MODULE_372 | MSigDB lists | MODULE_372 | 22 | 6 | 17758 | 1761 |
KLHL2,CCNE2,FOXP2,SOX8,TWSG1,KIF11 |
| 1.747e-02 | -4.05 | MODULE_71 | MSigDB lists | MODULE_71 | 22 | 6 | 17758 | 1761 |
SLC7A2,LTBP2,SLC12A2,SLC9A6,SLC16A5,ABCG1 |
| 1.747e-02 | -4.05 | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | MSigDB lists | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | 22 | 6 | 17758 | 1761 |
KLK6,KLK7,DUSP4,SULT2B1,RIMS2,DAPK1 |
| 1.747e-02 | -4.05 | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | MSigDB lists | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | 22 | 6 | 17758 | 1761 |
ERBB2,IRS2,TGFBR1,ERBB3,DACT1,FZD7 |
| 1.747e-02 | -4.05 | NEWMAN_ERCC6_TARGETS_UP | MSigDB lists | NEWMAN_ERCC6_TARGETS_UP | 22 | 6 | 17758 | 1761 |
HERC5,MYLIP,STEAP1,ABCB1,LITAF,PCSK5 |
| 1.747e-02 | -4.05 | BIOCARTA_INSULIN_PATHWAY | MSigDB lists | BIOCARTA_INSULIN_PATHWAY | 22 | 6 | 17758 | 1761 |
SLC2A4,ELK1,FOS,RASA1,PIK3R1,PIK3CA |
| 1.749e-02 | -4.05 | energy derivation by oxidation of organic compounds | biological process | GO:0015980 | 330 | 46 | 16441 | 1675 |
PRKAA2,ACACB,GAA,PINK1,PPP1R2,UGP2,SLC25A13,IQGAP1,SLC25A27,CACNA2D2,CALM3,NDUFA4,ITPR2,SLC1A3,COX6C,PRKACA,CALM2,IL6ST,ATP5H,KCNS3,BAX,CACNA1D,PHKA2,NDUFA12,GFPT1,PGM1,PMPCB,AKT1,CALM1,OGDHL,ACO1,PRKAR2B,ITPR3,SLC25A5,IDH1,LEPR,COX20,GNAS,PRKAG2,ALDH5A1,SLC25A4,ITPR1,NR4A3,DHTKD1,PGM2L1,MDH1 |
| 1.751e-02 | -4.04 | GSE17721_0.5H_VS_8H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_POLYIC_BMDM_DN | 195 | 29 | 17758 | 1761 |
GCA,NR3C1,ABCG2,EFHD2,NDRG2,IGSF8,SPTLC2,RNPEP,SH3KBP1,ARF4,EDNRA,ENDOD1,PTPRJ,ADORA1,CTSC,CDK16,RND3,LMO4,STK38,ITPR1,HDAC1,SNX16,CD70,MDFIC,CENPE,HMGA1,CACNA1D,MAP3K5,PTPRE |
| 1.752e-02 | -4.04 | Mitotic Prometaphase | REACTOME pathways | R-HSA-68877 | 108 | 19 | 8202 | 867 |
PLK1,ZWINT,CENPA,SPC25,CENPI,CDC20,NDC80,CDCA8,NUF2,CCNB1,CENPN,CDK1,PPP2R5A,CDCA5,BUB1,CENPE,NDE1,CCNB2,NUP85 |
| 1.754e-02 | -4.04 | TRANSPORT | MSigDB lists | TRANSPORT | 785 | 96 | 17758 | 1761 |
SLC2A4,SORBS1,RALBP1,SLC25A13,TP53,ARFGEF1,SLC7A2,SYTL4,BCL2L1,CACNB4,SLC20A1,BARD1,ERP29,ZFYVE9,SYTL2,APPBP2,ABCD4,ZFYVE16,ATP6V0B,SCNN1A,AP1M2,CDH1,STIM1,SLC44A1,STEAP2,KCNS3,BCL6,ABCA2,TRPC1,TINAGL1,SCN2A,LMAN1,F2R,TRAM1,ATG4D,SEC23A,AKT1,COG2,KIF1C,HTATIP2,SLC11A2,ICMT,SLC25A5,EDNRA,OPTN,KCNMB4,SLC25A4,KCNK1,CORO1C,ATP7B,ARF6,ABCA1,SCN5A,LASP1,ARAP3,NFKBIE,PEX6,GGA1,FXYD3,ABCG2,PDIA3,SLC1A3,AIP,ATG4A,M6PR,KIF5B,DOPEY2,ADORA1,GATA2,KCNN4,SLC16A6,KIF13B,BAX,SLC44A2,SORL1,SGK1,CACNA1D,SLC16A5,KDELR1,ABCC1,MDFI,KCNJ12,KIF20A,PPARA,STRADB,NPC2,MAPK8IP1,KLHL2,ABCB1,SH3BP4,CTSA,LTBP2,PLIN3,ARSB,NRBP1,ABCG1 |
| 1.755e-02 | -4.04 | NEDD4 (neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase) | protein interactions | 4734 | 281 | 42 | 16036 | 1726 |
CASP3,SCN5A,CAMK1D,TTYH3,SH3KBP1,WEE1,SCNN1A,IGF1R,TAF1B,PTEN,SIVA1,N4BP3,TMEM51,SGK1,ERBB3,RASGEF1A,SPRY2,SYK,MAP3K3,PLK1,AKT1,RAPGEF2,PYM1,LITAF,SLC11A2,YES1,CDK5R1,GABARAPL1,MAP2,FGFR2,STK26,PLK2,ABCB1,ARRB1,ARRDC1,GRIN2D,YOD1,ANXA9,LRRK1,MAP3K5,GUCD1,NDFIP1 |
| 1.755e-02 | -4.04 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 281 | 42 | 16036 | 1726 |
UNKL,RUNX2,TBC1D1,DCAF7,SOX9,TP53,DHX8,TGFBR1,ZFYVE9,MECOM,WWP2,ST5,PIK3CA,WWP1,ARL4D,CITED2,ETV4,TRIM62,EPB41L5,TGIF1,RHOA,AKT1,ITCH,S100A4,RGCC,LITAF,RUNX3,RAB38,ERBB2IP,SLC25A5,RANBP9,PIAS3,NCOA3,RBL1,HOXA9,HDAC1,KLF5,IRF7,FHL1,PLIN3,TOB1,DOCK9 |
| 1.761e-02 | -4.04 | OGFOD1 (2-oxoglutarate and iron-dependent oxygenase domain containing 1) | protein interactions | 55239 | 32 | 8 | 16036 | 1726 |
STK26,GNPDA1,PRCP,EZR,AHCY,ISOC1,RAD23A,PDIA4 |
| 1.763e-02 | -4.04 | TLE1 (transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)) | protein interactions | 7088 | 106 | 19 | 16036 | 1726 |
SIRT1,HES1,RUNX2,CUL4B,SAT1,AES,RUNX3,BCL2L1,MORF4L2,CDK1,SIX4,CDKN2C,SS18,IL6ST,PEX2,NOD2,HDAC1,TLE1,ARL4D |
| 1.763e-02 | -4.04 | GUILLAUMOND_KLF10_TARGETS_UP | MSigDB lists | GUILLAUMOND_KLF10_TARGETS_UP | 48 | 10 | 17758 | 1761 |
LASP1,KIFC2,SERPINE2,CELSR2,ATP8A1,TFAP2C,SLC25A30,DAG1,STEAP1,COL16A1 |
| 1.763e-02 | -4.04 | GYORFFY_DOXORUBICIN_RESISTANCE | MSigDB lists | GYORFFY_DOXORUBICIN_RESISTANCE | 48 | 10 | 17758 | 1761 |
AIM1L,TYMP,TIMP2,FAT4,AASS,FAAH,BMP7,NETO2,ABCB1,SNTB1 |
| 1.767e-02 | -4.04 | PET | prosite domains | PS51303 | 6 | 3 | 11866 | 1235 |
PRICKLE1,PRICKLE3,LMCD1 |
| 1.767e-02 | -4.04 | FBA | prosite domains | PS51114 | 6 | 3 | 11866 | 1235 |
FBXO6,FBXO27,FBXO2 |
| 1.768e-02 | -4.04 | cellular response to organic cyclic compound | biological process | GO:0071407 | 364 | 50 | 16441 | 1675 |
CASP3,NKX3-1,SSH1,IL15,THRA,GABRG2,IL18,ITPR2,CCNB1,PRKACA,PDGFB,TFAP4,CYP1A1,CDH1,BMP7,CDKN1B,PDE4D,IFIT1,KLF9,PIM1,TIPARP,NR2C1,SP5,PAQR7,CYP1B1,THRB,SHMT1,AKT1,NR3C1,RAPGEF2,NR4A1,CASP9,PPARA,EZR,AGO4,PRKRA,ELK1,GPLD1,GNAS,FECH,NCOA3,ATP1A1,NR1D2,NR4A3,NR4A2,GPER1,NR3C2,RARG,TMEM173,NR2C2 |
| 1.769e-02 | -4.03 | LAU_APOPTOSIS_CDKN2A_UP | MSigDB lists | LAU_APOPTOSIS_CDKN2A_UP | 55 | 11 | 17758 | 1761 |
DAP,NFKBIA,MYBL2,TP53,CDKN1B,TNFRSF12A,BCL2L1,TRAF5,CARD10,TNFSF9,FAS |
| 1.769e-02 | -4.03 | CUB_dom | interpro domains | IPR000859 | 55 | 11 | 18293 | 1814 |
PDGFC,PCOLCE,ST14,MEGF8,BMP1,NETO2,ATRNL1,KREMEN1,DCBLD1,NRP2,TLL2 |
| 1.777e-02 | -4.03 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 187 | 28 | 17758 | 1761 |
PGM1,TBC1D1,RASSF7,HEXB,TFAP2C,BTN3A1,CYB561,RNF113A,VASH1,H2AFV,SLC20A1,LGALS3BP,MAPK8IP1,PDIA4,ELF3,DIRAS3,EPCAM,PSMD1,SP100,TJP3,SH3BP1,FGFR2,PRCP,SPINT2,SFMBT1,AURKA,CD70,S100A13 |
| 1.777e-02 | -4.03 | GSE13306_TREG_RA_VS_TCONV_RA_UP | MSigDB lists | GSE13306_TREG_RA_VS_TCONV_RA_UP | 187 | 28 | 17758 | 1761 |
REPS2,CELSR2,S100A4,PLEKHO1,MGAT4B,GABRG2,DIAPH2,CNTNAP2,OAT,GLT8D2,PRIM1,CXXC4,CPNE2,IDE,DDOST,ANKRD6,DBI,SECTM1,SLC44A2,ADAM15,RAB20,MDFIC,RTKN2,MDH1,ARPC2,F2R,SLC12A2,USP43 |
| 1.777e-02 | -4.03 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 187 | 28 | 17758 | 1761 |
BIN1,RMND5A,GAA,RHOA,MPP1,IQGAP1,TSC22D3,BLVRB,HEXB,PDIA3,EIF2AK1,TGOLN2,TEX2,FAM198B,BLVRA,FOS,FBLN1,APPBP2,SGPL1,LRRC42,ATP1A1,DDOST,IMPAD1,AMMECR1,PCYOX1,TAGLN2,S100A6,KLF7 |
| 1.777e-02 | -4.03 | GSE1460_DP_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_UP | 187 | 28 | 17758 | 1761 |
CD99,ORAI2,LOC81691,TIMP2,ALDH2,TXN,CHCHD7,TBC1D1,MPP1,CORO2A,MTL5,DHX8,LRRC1,PHLPP1,MNS1,DGKE,FECH,CDKN2C,NEIL1,METTL7A,MITF,TBCD,PLK4,DAPK1,DHTKD1,SERPINI1,FAIM,PPP2R2D |
| 1.777e-02 | -4.03 | GSE14308_TH2_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_UP | 187 | 28 | 17758 | 1761 |
ERLEC1,FOXM1,TMEM41B,CIT,SOX9,EPS8,PRKACA,AHRR,HS6ST1,WEE1,MDM1,GALNS,PASK,ALDH1A3,SRR,TMEM143,FAM63A,GTF2F2,OTUB2,ECI2,PLEKHF1,GRIN2D,MDFIC,NFKBIZ,NDE1,SPRY2,APOL2,CCDC88A |
| 1.777e-02 | -4.03 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_DN | 187 | 28 | 17758 | 1761 |
SUN1,S100A11,BCL9,SERTAD3,AK4,KCTD12,NENF,CAMK1D,PRKRA,CYB5A,NIN,TMEM63A,IER3,ATP6V0B,DDOST,WFS1,SPINT2,FGD6,SGK1,IRF2,HOXB13,NCAPG2,SMYD5,GLCCI1,NR2C1,SMAGP,ABCC1,CD33 |
| 1.777e-02 | -4.03 | lumenal side of endoplasmic reticulum membrane | cellular component | GO:0098553 | 28 | 7 | 17570 | 1756 |
HLA-B,TAPBP,HLA-C,BCAP31,HLA-F,HLA-E,HLA-A |
| 1.777e-02 | -4.03 | trans-Golgi network transport vesicle | cellular component | GO:0030140 | 28 | 7 | 17570 | 1756 |
TGOLN2,SORT1,SLC2A4,RAB27B,NRGN,STEAP2,FURIN |
| 1.777e-02 | -4.03 | integral component of lumenal side of endoplasmic reticulum membrane | cellular component | GO:0071556 | 28 | 7 | 17570 | 1756 |
HLA-B,TAPBP,HLA-C,BCAP31,HLA-E,HLA-F,HLA-A |
| 1.778e-02 | -4.03 | lung-carcinoma-signet_ring_cell_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-signet_ring_cell_adenocarcinoma | 11 | 4 | 17775 | 1757 |
KIF5B,ERBB2,AKT1,PIK3CA |
| 1.778e-02 | -4.03 | soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa) | COSMIC cancer mutations | soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa) | 11 | 4 | 17775 | 1757 |
AKT1,GNA11,PIK3CA,TP53 |
| 1.778e-02 | -4.03 | pleomorphic_carcinoma | COSMIC cancer mutations | pleomorphic_carcinoma | 11 | 4 | 17775 | 1757 |
KIF5B,ERBB2,PIK3CA,TP53 |
| 1.778e-02 | -4.03 | perivascular_epithelioid_cell_tumour_(PEComa) | COSMIC cancer mutations | perivascular_epithelioid_cell_tumour_(PEComa) | 11 | 4 | 17775 | 1757 |
AKT1,GNA11,PIK3CA,TP53 |
| 1.778e-02 | -4.03 | signet_ring_cell_adenocarcinoma | COSMIC cancer mutations | signet_ring_cell_adenocarcinoma | 11 | 4 | 17775 | 1757 |
KIF5B,ERBB2,AKT1,PIK3CA |
| 1.785e-02 | -4.03 | WWP1 (WW domain containing E3 ubiquitin protein ligase 1) | protein interactions | 11059 | 71 | 14 | 16036 | 1726 |
PRKAA2,PHF20L1,SCNN1A,RUNX2,PTEN,TFAP2A,TMEM51,EZR,ARRDC1,KLF5,WWP1,HSPB1,DAG1,RASA1 |
| 1.785e-02 | -4.03 | BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) | protein interactions | 701 | 71 | 14 | 16036 | 1726 |
PLK1,ZWINT,UGP2,RPL39,PTTG1,CDC20,NDC80,HDAC1,NUF2,BUB1,CENPE,UBE2C,HSPB1,PSMA4 |
| 1.790e-02 | -4.02 | PRKCB (protein kinase C, beta) | protein interactions | 5579 | 99 | 18 | 16036 | 1726 |
DDX58,MBP,HABP4,GRIN1,GABRG2,CDK1,GRM5,TOP2A,ADRBK1,H1F0,GRIN2D,NCAM1,TIAM1,NRGN,AFAP1,OCLN,DVL2,GCNT1 |
| 1.791e-02 | -4.02 | chest | COSMIC cancer mutations | chest | 147 | 23 | 17775 | 1757 |
ADAMTS2,AKT1,RET,PIK3R1,TP53,ERBB2,TNS1,IDH1,GNA11,LMNA,HLA-A,KIF5B,EPHA10,PLCH1,PTPRJ,PTEN,FGFR2,PTK7,MITF,PIK3CA,ARRB1,PTPRE,MYO5A |
| 1.794e-02 | -4.02 | human chr8p21.2 | chromosome location | human chr8p21.2 | 22 | 5 | 26250 | 1887 |
CDCA2,NKX3-1,DOCK5,PBK,SH2D4A |
| 1.796e-02 | -4.02 | phosphatidylinositol phosphate kinase activity | molecular function | GO:0016307 | 16 | 5 | 16491 | 1673 |
PIK3C2B,PIK3CD,PIKFYVE,PIK3CA,PIP4K2C |
| 1.796e-02 | -4.02 | phospholipid-translocating ATPase activity | molecular function | GO:0004012 | 16 | 5 | 16491 | 1673 |
ATP8B1,ATP8B3,ATP9A,ATP8A1,ATP10D |
| 1.796e-02 | -4.02 | oxidoreductase activity, oxidizing metal ions | molecular function | GO:0016722 | 16 | 5 | 16491 | 1673 |
CYB561,FTH1,STEAP1,CYBRD1,STEAP2 |
| 1.796e-02 | -4.02 | NAD-dependent protein deacetylase activity | molecular function | GO:0034979 | 16 | 5 | 16491 | 1673 |
SIRT1,HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.798e-02 | -4.02 | APOBEC_N | interpro domains | IPR013158 | 11 | 4 | 18293 | 1814 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 1.798e-02 | -4.02 | Insulin_GF-bd_Cys-rich_CS | interpro domains | IPR017891 | 11 | 4 | 18293 | 1814 |
NOV,IGFBP2,CTGF,CYR61 |
| 1.798e-02 | -4.02 | His_deacetylse_dom | interpro domains | IPR023801 | 11 | 4 | 18293 | 1814 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.798e-02 | -4.02 | Pept_his_AS | interpro domains | IPR025660 | 11 | 4 | 18293 | 1814 |
CTSL,TINAGL1,CTSC,CTSV |
| 1.798e-02 | -4.02 | AdipoR/HlyIII-related | interpro domains | IPR004254 | 11 | 4 | 18293 | 1814 |
ADIPOR1,MMD,PAQR5,PAQR7 |
| 1.798e-02 | -4.02 | Amidohydro-rel | interpro domains | IPR006680 | 11 | 4 | 18293 | 1814 |
DPYSL5,AMDHD1,DPYSL2,DPYSL3 |
| 1.798e-02 | -4.02 | Frizzled | interpro domains | IPR000539 | 11 | 4 | 18293 | 1814 |
FZD5,FZD4,FZD7,FZD6 |
| 1.798e-02 | -4.02 | His_deacetylse | interpro domains | IPR000286 | 11 | 4 | 18293 | 1814 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.798e-02 | -4.02 | SPINDLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | SPINDLE_ORGANIZATION_AND_BIOGENESIS | 11 | 4 | 17758 | 1761 |
KIF23,TUBG1,SUN2,KIF11 |
| 1.798e-02 | -4.02 | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP | MSigDB lists | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP | 11 | 4 | 17758 | 1761 |
NRG2,CDH1,ALCAM,DAPK1 |
| 1.798e-02 | -4.02 | ROZANOV_MMP14_CORRELATED | MSigDB lists | ROZANOV_MMP14_CORRELATED | 11 | 4 | 17758 | 1761 |
PIK3CD,NR3C1,STK38,DAPK1 |
| 1.798e-02 | -4.02 | PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION | MSigDB lists | PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION | 11 | 4 | 17758 | 1761 |
AKT1,F2R,ZFYVE9,BCL6 |
| 1.798e-02 | -4.02 | VACUOLAR_MEMBRANE | MSigDB lists | VACUOLAR_MEMBRANE | 11 | 4 | 17758 | 1761 |
LAMP2,CD63,LAMP3,ABCA2 |
| 1.798e-02 | -4.02 | CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 11 | 4 | 17758 | 1761 |
ITPR2,ITPR3,ITPR1,ATP2B1 |
| 1.798e-02 | -4.02 | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_DN | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_DN | 11 | 4 | 17758 | 1761 |
TOP2A,SPC25,CDK1,NDC80 |
| 1.798e-02 | -4.02 | ST_STAT3_PATHWAY | MSigDB lists | ST_STAT3_PATHWAY | 11 | 4 | 17758 | 1761 |
PIAS3,JAK1,PTPRU,JAK3 |
| 1.798e-02 | -4.02 | REGULATION_OF_VIRAL_REPRODUCTION | MSigDB lists | REGULATION_OF_VIRAL_REPRODUCTION | 11 | 4 | 17758 | 1761 |
TOP2A,MDFIC,TNIP1,APOBEC3G |
| 1.798e-02 | -4.02 | APOPTOTIC_MITOCHONDRIAL_CHANGES | MSigDB lists | APOPTOTIC_MITOCHONDRIAL_CHANGES | 11 | 4 | 17758 | 1761 |
BCL2L1,DNM1L,IFI6,BAX |
| 1.798e-02 | -4.02 | PID_P38_GAMMA_DELTA_PATHWAY | MSigDB lists | PID_P38_GAMMA_DELTA_PATHWAY | 11 | 4 | 17758 | 1761 |
SNTA1,CCND1,PKN1,MAPK12 |
| 1.799e-02 | -4.02 | SORD (sorbitol dehydrogenase) | protein interactions | 6652 | 51 | 11 | 16036 | 1726 |
PGM1,GCLM,BROX,AKR1B1,ALDH7A1,PIEZO1,TIPRL,ACOT7,FAH,PLS3,RAD23A |
| 1.800e-02 | -4.02 | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | 179 | 27 | 17758 | 1761 |
CASP3,ADD1,SNTB2,CUL4B,IL13RA1,MRAS,SAMD9,TRIB2,LHFPL2,SLC25A43,PPP2R3A,LMNA,EPDR1,ZDHHC21,FECH,MARCH8,TMEM164,DOPEY2,C19orf66,PLCG2,SLC44A1,FAM195A,ECI2,RCAN3,LTA4H,AHR,PARP9 |
| 1.803e-02 | -4.02 | KISc | smart domains | SM00129 | 44 | 10 | 9131 | 997 |
KIF5B,KIFC2,KIF20A,KIF14,KIF13B,KIF23,KIF1C,KIF13A,CENPE,KIF11 |
| 1.808e-02 | -4.01 | positive regulation of lipase activity | biological process | GO:0060193 | 97 | 17 | 16441 | 1675 |
RHOA,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,ARF4,PLIN5,EDNRA,CALM2,PLCG1,ADRBK1,CYR61,FGFR2,ITPR1,PLCB2 |
| 1.808e-02 | -4.01 | FASLG (Fas ligand (TNF superfamily, member 6)) | protein interactions | 356 | 92 | 17 | 16036 | 1726 |
DOCK4,PACSIN2,RHOA,MOSPD2,MACC1,PIK3R1,RGS20,EZR,EIF2AK1,TEC,YES1,CACNB4,FAS,TJP3,SNX18,PIK3CA,OSTF1 |
| 1.808e-02 | -4.01 | CRKL (v-crk avian sarcoma virus CT10 oncogene homolog-like) | protein interactions | 1399 | 92 | 17 | 16036 | 1726 |
GRN,PLSCR1,INPP5D,PIK3R1,PPFIBP2,ERBB2,BCAR1,LMNA,MSL1,IGF1R,PTEN,HNRNPH2,AOX1,ERBB3,SYK,GAB1,SEPHS1 |
| 1.809e-02 | -4.01 | SUMO4 (small ubiquitin-like modifier 4) | protein interactions | 387082 | 78 | 15 | 16036 | 1726 |
TOP2A,ENO2,NR3C1,NFKBIA,SPINT2,TFAP2A,PDIA3,DNAJB11,ARHGDIB,PDIA6,IDH1,GSTP1,FOS,LMNA,PRDX4 |
| 1.810e-02 | -4.01 | negative regulation of biosynthetic process | biological process | GO:0009890 | 1481 | 175 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,ZFP36,SIVA1,MITF,FOSB,PASK,DLG1,IRF2,CRY2,ZBTB18,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,TRIM8,ITCH,CBX6,TFAP2C,EZR,AGO4,LOXL2,PIF1,EDNRA,AHRR,ENPP1,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,GLA,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,MARCH8,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,MDFIC,RFX5,PIM1,ETV7,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,JAK3,TOB1,RARG,EGLN1,NF2,S100A11,FOXM1,THRA,INPP5D,TP53,OSR2,PDGFA,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,NR2C1,CHP1,SIRT1,DRAP1,ERBB2IP,RAD17,H2AFV,ARHGAP35,NFIX,ATP1A1,RBL1,WFS1,PEX2,OVOL1,TLE1,SLC27A1,NRG1,IRF7,KLF5,CBX7,GLIS3,NKX3-1,TNRC6C,DEPDC1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,GSTP1,FGF19,SIX4,FZD6,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,RNF128,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CITED2,CNOT6L,TRIM62,NCOA2,NFE2L3,TGIF1,HES1,RHOA,IFITM3,RAPGEF2,GCLC,PPARA,PRICKLE1,RUNX3,LEPR,PITX2,BANK1,FGFR2,NR1D2,ACVRL1,TBX18,NMI,NR4A3,ARRB1,ITGAV,HMGA1,GPER1,OSR1,SOX8,CPEB2,AHR,PKIA,ZBTB33,JARID2 |
| 1.810e-02 | -4.01 | intramolecular oxidoreductase activity | molecular function | GO:0016860 | 54 | 11 | 16491 | 1673 |
GNPDA1,ERO1A,TMX4,PDIA5,ECI2,PDIA3,PDIA6,TXNDC11,ERP29,PTGES,PDIA4 |
| 1.811e-02 | -4.01 | uDENN | smart domains | SM00800 | 15 | 5 | 9131 | 997 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.812e-02 | -4.01 | Amino Sugar Metabolism | SMPDB pathways | SMP00045 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.812e-02 | -4.01 | G(M2)-Gangliosidosis: Variant B- Tay-sachs disease | SMPDB pathways | SMP00534 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.812e-02 | -4.01 | Tay-Sachs Disease | SMPDB pathways | SMP00390 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.812e-02 | -4.01 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00216 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.812e-02 | -4.01 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00217 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.812e-02 | -4.01 | Salla Disease/Infantile Sialic Acid Storage Disease | SMPDB pathways | SMP00240 | 17 | 6 | 978 | 131 |
GFPT1,CMAS,NANS,UAP1,GNPDA1,GNE |
| 1.814e-02 | -4.01 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 288 | 40 | 17758 | 1761 |
MAN2B2,ILDR1,KLK10,SORBS1,TSPAN15,FBXO2,ERBB2,PARM1,B3GALNT1,NOV,CTGF,ITGB8,KCNN4,ZFP36,BMP7,KLF3,FOSB,IGFBP2,ALDH7A1,CNOT6L,RAB27B,SMAGP,EPB41L5,MX1,PDGFC,TNIP1,NR4A1,PDE5A,TNS1,TXNDC11,FOS,CRISPLD2,FUCA1,CACHD1,DNAJC10,FGFR2,COL13A1,PER3,DEF6,CYBRD1 |
| 1.815e-02 | -4.01 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | molecular function | GO:0016620 | 34 | 8 | 16491 | 1673 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH1A3,ALDH7A1,FAR2,ALDH3A2 |
| 1.818e-02 | -4.01 | regulation of blood vessel endothelial cell migration | biological process | GO:0043535 | 47 | 10 | 16441 | 1675 |
PLCG1,AKT1,ACVRL1,PRCP,RGCC,VASH1,PDGFB,HSPB1,SRPX2,HDAC9 |
| 1.818e-02 | -4.01 | mammary gland morphogenesis | biological process | GO:0060443 | 47 | 10 | 16441 | 1675 |
NCOA3,FGFR2,CSF1,ERBB2,TFAP2C,SCRIB,ETV4,SLC12A2,CAPN1,ELF3 |
| 1.818e-02 | -4.01 | peptidyl-threonine modification | biological process | GO:0018210 | 47 | 10 | 16441 | 1675 |
GALNT3,ADRBK1,AKT1,STK39,TGFBR1,PKN1,PRKACA,HIPK3,CDK1,CDK5R1 |
| 1.818e-02 | -4.01 | negative regulation of viral genome replication | biological process | GO:0045071 | 47 | 10 | 16441 | 1675 |
MX1,FAM111A,PLSCR1,TNIP1,APOBEC3D,IFITM3,APOBEC3H,OAS3,IFIT1,APOBEC3G |
| 1.818e-02 | -4.01 | negative regulation of DNA binding | biological process | GO:0043392 | 47 | 10 | 16441 | 1675 |
ZNF462,CTNNBIP1,TFAP4,SP100,NFKBIA,HABP4,NEK2,PPARA,NFIB,MDFI |
| 1.818e-02 | -4.01 | regulation of actin filament depolymerization | biological process | GO:0030834 | 47 | 10 | 16441 | 1675 |
SWAP70,PLEKHH2,ADD1,EPS8,TRIOBP,SPTBN5,TMOD2,SHROOM2,F2RL1,SPTB |
| 1.820e-02 | -4.01 | BENPORATH_NOS_TARGETS | MSigDB lists | BENPORATH_NOS_TARGETS | 171 | 26 | 17758 | 1761 |
IER5L,NFE2L3,MTM1,SPRED1,CDK17,GRHL2,PDCL,ROR1,EPHA1,ICMT,DHRS3,PPP2R3A,COL12A1,DPYSL3,TOP2A,ADD3,CA2,CTGF,FGFR2,DPYSL2,GNPTAB,BMP7,SLC44A1,PRKCDBP,KLF5,JARID2 |
| 1.823e-02 | -4.00 | human chr4p14 | chromosome location | human chr4p14 | 30 | 6 | 26250 | 1887 |
ARAP2,RELL1,RBM47,TBC1D1,FAM114A1,KLF3 |
| 1.824e-02 | -4.00 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | 77 | 14 | 17758 | 1761 |
RASGRF1,TIMP2,IGF1R,PRSS23,EPAS1,PIK3R1,NR4A3,SGK1,ARHGDIB,NTN4,NRG1,ERBB3,HOXB2,PPP2R3A |
| 1.824e-02 | -4.00 | REACTOME_MITOTIC_G2_G2_M_PHASES | MSigDB lists | REACTOME_MITOTIC_G2_G2_M_PHASES | 77 | 14 | 17758 | 1761 |
PLK1,WEE1,CEP70,CNTRL,NEK2,PLK4,TUBG1,PRKAR2B,PKMYT1,CCNB1,CEP41,PRKACA,CCNB2,CDK1 |
| 1.824e-02 | -4.00 | GNF2_SPTA1 | MSigDB lists | GNF2_SPTA1 | 77 | 14 | 17758 | 1761 |
FECH,MARCH8,CA2,ERMAP,H1F0,GCLC,MPP1,BLVRB,FBXO9,EIF2AK1,MINPP1,SPTB,TRAK2,RAD23A |
| 1.826e-02 | -4.00 | regulation of cytoplasmic transport | biological process | GO:1903649 | 433 | 58 | 16441 | 1675 |
DDX58,TXN,PINK1,NFKBIE,THRA,UBASH3B,RAB23,CALM3,PSMD10,TGFBR1,IL18,PRKACA,BARD1,APC2,IL18R1,BCAP31,IER3,CALM2,NOV,CDH1,SP100,DACT1,BMP7,CABP1,FAM20B,BAX,UBE2J1,TRPC1,SORL1,DAB2IP,MDFIC,PDE4D,WNT3A,F2R,MDFI,CHP1,SIRT1,HES1,RHOA,ERLEC1,CALM1,PIK3R1,LITAF,NBPF3,EZR,PRKCQ,SNX12,FZD7,PLCG1,TMEM30A,NFKBIA,INPP4B,NRG1,YOD1,GPER1,FZD5,TMEM173,PKIA |
| 1.827e-02 | -4.00 | negative regulation of platelet activation | biological process | GO:0010544 | 16 | 5 | 16441 | 1675 |
PDGFA,SERPINE2,PDGFB,UBASH3B,PRKG1 |
| 1.827e-02 | -4.00 | mast cell degranulation | biological process | GO:0043303 | 16 | 5 | 16441 | 1675 |
PIK3CD,GATA2,S100A13,RASGRP1,NR4A3 |
| 1.827e-02 | -4.00 | regulation of hydrogen peroxide-induced cell death | biological process | GO:1903205 | 16 | 5 | 16441 | 1675 |
TXN,PINK1,HDAC6,STK26,NR4A3 |
| 1.827e-02 | -4.00 | negative regulation of lipid storage | biological process | GO:0010888 | 16 | 5 | 16441 | 1675 |
ITGAV,ABCA1,NFKBIA,ABCG1,PPARA |
| 1.827e-02 | -4.00 | negative regulation of cell aging | biological process | GO:0090344 | 16 | 5 | 16441 | 1675 |
SIRT1,TWIST1,FOXM1,PTEN,BCL6 |
| 1.827e-02 | -4.00 | mast cell activation involved in immune response | biological process | GO:0002279 | 16 | 5 | 16441 | 1675 |
PIK3CD,GATA2,S100A13,RASGRP1,NR4A3 |
| 1.830e-02 | -4.00 | regulation of defense response | biological process | GO:0031347 | 757 | 95 | 16441 | 1675 |
LAMP1,NLRX1,IL15,RPS6KA1,PSME2,LMCD1,TAP1,PSME1,IL18,ITPR2,SLC7A2,PRKACA,IER3,CALM2,NOV,PSMD1,AP1M2,RPS6KA2,IL6ST,TSPAN6,PLCG2,BCL6,DUSP10,IFIT1,SCARA3,LGMN,APOBEC3G,SMAGP,RASGRP1,CD55,RIPK2,TNIP1,ITCH,PBK,USP18,PTGER4,SLC35C1,ATP1B1,F12,ITPR3,DUSP4,CASP4,ABR,SOCS3,GPRC5B,JAK1,CDK19,TRAF3IP1,NOD2,IRF7,F2RL1,DDX58,HLA-E,CALM3,PSMD10,HERC5,SLC1A3,ETS1,GSTP1,HLA-A,ADORA1,PIK3AP1,FAM13B,MAPK11,ALPK1,CNPY3,SYK,PARP9,KLK5,PLSCR1,PSMB4,MICB,CALM1,PPARA,ELK1,FOS,PSMA4,CTSL,MAPKAPK2,HLA-B,NR1D2,PVRL2,PELI2,NFKBIA,ITPR1,NMI,NLRC5,ERAP1,MDH1,KLK7,STK39,GPER1,NDFIP1,IFIH1,TMEM173 |
| 1.831e-02 | -4.00 | angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | angioimmunoblastic_T_cell_lymphoma | 272 | 38 | 17775 | 1757 |
CPEB4,TP53,SAMD9,ITPR2,PHLPP1,ETS1,TNFSF9,SLC9A2,CCND1,BTG3,MUC16,PTEN,GATA2,FABP6,PLCG2,BCL6,SGK1,CD70,NOTCH3,PIM1,SYK,PDGFC,SMARCA2,RHOA,CELSR2,TACC1,NR3C1,BCL9,PIK3R1,UBE2A,IDH1,FAS,GNAS,PLCG1,JAK1,TMEM30A,NFKBIA,JAK3 |
| 1.835e-02 | -4.00 | DENN | pfam domains | PF02141 | 16 | 5 | 16629 | 1696 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.842e-02 | -3.99 | TTCYRGAA_UNKNOWN | MSigDB lists | TTCYRGAA_UNKNOWN | 314 | 43 | 17758 | 1761 |
NCKAP5,CDH22,DNAJB2,SLC25A27,CD274,CNTNAP2,MORF4L2,POMGNT1,PKN1,FAM101B,PDGFB,CYP39A1,APLP2,ADRBK1,GRHL1,CYR61,ARSG,TSPAN6,PASK,BCL6,MYT1,RIMS2,SCN3A,TGIF1,PGM1,STAT4,LYRM1,PIK3R1,SLC35C1,VWA1,LRRC1,IDH1,MAP3K6,MUM1L1,CXXC4,TMC5,GRIN2D,NRGN,HSPB1,SEMA3A,AIFM3,ACOT7,JARID2 |
| 1.842e-02 | -3.99 | Reactions specific to the complex N-glycan synthesis pathway | REACTOME pathways | R-HSA-975578 | 6 | 3 | 8202 | 867 |
MAN2A2,FUCA1,FUT8 |
| 1.842e-02 | -3.99 | Cam-PDE 1 activation | REACTOME pathways | R-HSA-111957 | 6 | 3 | 8202 | 867 |
CALM2,CALM3,CALM1 |
| 1.842e-02 | -3.99 | IRF3 mediated activation of type 1 IFN | REACTOME pathways | R-HSA-1606341 | 6 | 3 | 8202 | 867 |
NLRP4,TMEM173,DTX4 |
| 1.844e-02 | -3.99 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | hsa00533 | 15 | 5 | 6908 | 758 |
B3GNT7,B3GNT2,B4GALT4,ST3GAL1,FUT8 |
| 1.844e-02 | -3.99 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | ko00533 | 15 | 5 | 6908 | 758 |
B3GNT7,B3GNT2,B4GALT4,ST3GAL1,FUT8 |
| 1.844e-02 | -3.99 | MSN (moesin) | protein interactions | 4478 | 121 | 21 | 16036 | 1726 |
RHOA,ENO2,PPP1R2,SELL,EZR,PRKCQ,IGSF8,ISYNA1,BCAP31,PDIA4,PLS3,FAS,RCN1,HLA-B,PAPSS1,AKR1B1,AHCY,TAGLN2,HSPB1,L1CAM,SYK |
| 1.844e-02 | -3.99 | midbody | cellular component | GO:0030496 | 130 | 21 | 17570 | 1756 |
PLK1,RHOA,SSH1,KIF20A,KLHL13,ASPM,SEPT6,IQGAP1,CDCA8,KIF23,KIF13A,PKN1,CDK1,KIF14,NEK2,AGBL5,TRIOBP,AURKA,CENPE,GEM,ARF6 |
| 1.846e-02 | -3.99 | host | cellular component | GO:0018995 | 11 | 4 | 17570 | 1756 |
IFIT1,LMAN1,AXL,TAP1 |
| 1.846e-02 | -3.99 | host cell | cellular component | GO:0043657 | 11 | 4 | 17570 | 1756 |
IFIT1,LMAN1,AXL,TAP1 |
| 1.847e-02 | -3.99 | protein localization to cell periphery | biological process | GO:1990778 | 151 | 24 | 16441 | 1675 |
KCNIP3,RAB3B,TSPAN15,CRB3,RAPGEF2,PKP2,EZR,F11R,MPP5,ARFRP1,KIF13A,ATP1B1,NUBP1,EMP2,BBS2,OPTN,RAB15,CDH1,ZDHHC23,DLG1,PLEKHF1,ATP1B3,PACSIN1,MYO5A |
| 1.847e-02 | -3.99 | BROWNE_HCMV_INFECTION_6HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_6HR_DN | 155 | 24 | 17758 | 1761 |
AMOTL2,MTM1,TGIF1,TRIM2,NR3C1,BCL9,STAU2,ITGA6,PIK3R1,PARP4,ARL4C,PRKAR2B,RNF113A,OSR2,HDAC9,WEE1,MDM1,FRY,RND3,DUSP10,CDKN1B,SGK1,GLB1L2,F2RL1 |
| 1.847e-02 | -3.99 | TAATGTG,MIR-323 | MSigDB lists | TAATGTG,MIR-323 | 155 | 24 | 17758 | 1761 |
MAP3K3,TGIF1,CLCN3,PPP4R4,CPEB4,CXorf57,MCFD2,PJA2,BORA,RANBP9,FANCI,ZDHHC21,NFIX,IRF2BPL,RCN1,CCND1,SLC4A4,RAB11FIP2,FAM20B,NR4A3,CDKN1B,PITPNA,ANO4,MYLIP |
| 1.853e-02 | -3.99 | MODULE_92 | MSigDB lists | MODULE_92 | 147 | 23 | 17758 | 1761 |
GRN,DLGAP1,PCDH1,NQO1,IL15,FURIN,TFAP2C,NRG2,IL18,MERTK,TNFSF9,NEO1,MDK,PDGFA,ADORA1,SCG2,LTBP2,WNT3A,NCAM1,ARL4D,S100A6,SNPH,SEMA3B |
| 1.853e-02 | -3.99 | WHITFIELD_CELL_CYCLE_S | MSigDB lists | WHITFIELD_CELL_CYCLE_S | 147 | 23 | 17758 | 1761 |
GCLM,ZWINT,KIFC2,OSGIN2,SLC25A27,COL7A1,PKMYT1,BBS2,FANCI,PRIM1,TOP2A,UBE2T,H1F0,CALD1,LMO4,REEP1,PHTF1,CDCA5,MITF,DONSON,EIF4EBP2,IFIT1,E2F8 |
| 1.854e-02 | -3.99 | negative regulation of protein binding | biological process | GO:0032091 | 68 | 13 | 16441 | 1675 |
CTNNBIP1,EPB41L5,PTPRF,NKX3-1,PPARA,BAX,AURKA,SORL1,TMBIM6,ADAM15,AES,IFIT1,PDGFB |
| 1.854e-02 | -3.99 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 68 | 13 | 16441 | 1675 |
CALM2,GNB5,STIM1,CABP1,CALM1,PLCG2,CALM3,TSPAN13,PDE4D,ATP1B1,PRKACA,CACNB4,MYO5A |
| 1.856e-02 | -3.99 | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 70 | 13 | 17775 | 1757 |
FOXP2,FADS2,SCG2,BMP7,SOX9,CUL4B,COL6A1,TP53,FAM102A,SGK1,PGM2L1,PIM1,SRPX2 |
| 1.857e-02 | -3.99 | receptor signaling protein activity | molecular function | GO:0005057 | 136 | 22 | 16491 | 1673 |
MAP3K3,ACVR1C,PDCL,ERBB2,TGFBR1,ITPR2,ITPR3,MAP3K6,PLCG1,ACVRL1,DOK4,FLRT3,ITPR1,MAP3K9,CDKN1B,STK39,MAPK11,MAP3K5,RGS14,TIAM1,SYK,MAPK12 |
| 1.858e-02 | -3.99 | embryonic forelimb morphogenesis | biological process | GO:0035115 | 34 | 8 | 16441 | 1675 |
RUNX2,HOXA9,TFAP2A,TWIST1,OSR2,OSR1,CRABP2,MECOM |
| 1.858e-02 | -3.99 | establishment of spindle localization | biological process | GO:0051293 | 34 | 8 | 16441 | 1675 |
CENPA,LLGL2,NDC80,NUSAP1,GPSM2,NDE1,ESPL1,SPRY2 |
| 1.858e-02 | -3.99 | negative regulation of blood circulation | biological process | GO:1903523 | 34 | 8 | 16441 | 1675 |
DOCK4,ATP1A1,ADORA1,ADRBK1,PDE5A,PDE4D,DOCK5,F2R |
| 1.861e-02 | -3.98 | putrescine degradation III | BIOCYC pathways | HUMAN_PWY-0 | 9 | 4 | 907 | 115 |
ALDH3B1,ALDH2,ALDH3A2,SAT1 |
| 1.863e-02 | -3.98 | lymphocyte homeostasis | biological process | GO:0002260 | 54 | 11 | 16441 | 1675 |
CASP3,AKT1,SIVA1,RC3H2,BAX,PPP2R3C,PIK3CD,PKN1,CCNB2,JAK3,FAS |
| 1.865e-02 | -3.98 | cell-cell adherens junction | cellular component | GO:0005913 | 55 | 11 | 17570 | 1756 |
PVRL4,CAMSAP3,SORBS1,CDH1,PVRL2,CDH3,SCRIB,TLN2,SHROOM2,DAG1,SMAGP |
| 1.867e-02 | -3.98 | GSE22886_CTRL_VS_LPS_24H_DC_UP | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_UP | 196 | 29 | 17758 | 1761 |
GCA,CHCHD7,TACC1,S100A4,ZCCHC24,SH3BGRL,NDUFA4,RNF113A,ISYNA1,MGST2,GTF2A2,VASH1,PDIA4,GNAS,C7orf49,CDK19,GDE1,METTL7A,ATP5H,MGAT4A,RPL39,BDH1,ADCK2,PLCB2,NRGN,ALDH3A2,SYK,DEF6,EGLN1 |
| 1.872e-02 | -3.98 | chondrocyte differentiation | biological process | GO:0002062 | 61 | 12 | 16441 | 1675 |
NOV,RUNX2,HSPG2,IMPAD1,SOX9,RUNX3,OSR2,OSR1,NFIB,RARG,GPLD1,SULF2 |
| 1.872e-02 | -3.98 | activation of phospholipase C activity | biological process | GO:0007202 | 61 | 12 | 16441 | 1675 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,EDNRA |
| 1.872e-02 | -3.98 | glycosaminoglycan catabolic process | biological process | GO:0006027 | 61 | 12 | 16441 | 1675 |
HMMR,GNS,FUCA1,HPSE,HSPG2,GUSB,GALNS,HEXB,SDC4,ARSB,SDC1,CHP1 |
| 1.875e-02 | -3.98 | regulation of insulin secretion | biological process | GO:0050796 | 191 | 29 | 16441 | 1675 |
ACVR1C,IQGAP1,SYBU,CACNA2D2,HMGN3,PRKAR2B,ITPR2,SYTL4,ITPR3,SLC25A5,PRKACA,SLC8B1,ANO1,GPLD1,GNAS,IRS2,NOV,SLC25A4,SYT7,CDK16,ITPR1,KCNS3,ARRB1,EFNA5,GPER1,SPCS3,CACNA1D,MYRIP,MYT1 |
| 1.876e-02 | -3.98 | V$FOXJ2_02 | MSigDB lists | V$FOXJ2_02 | 221 | 32 | 17758 | 1761 |
LTBP1,TRIM2,CCDC109B,CAST,TRIB2,DNAJB9,NEO1,HDAC9,MECOM,NPNT,ARSG,FRAS1,KLF3,BCL6,ATRNL1,DIXDC1,PDE4D,PHF20L1,ACVR1C,UTRN,SPTLC2,NFIB,NFIX,MAP2,HOXA9,INPP4B,FAM117A,ARF6,LEMD1,SEMA3A,TOB1,LIFR |
| 1.878e-02 | -3.97 | actin filament organization | biological process | GO:0007015 | 175 | 27 | 16441 | 1675 |
WASF3,SORBS1,RHOA,ADD1,TMSB15A,FMN1,EPS8,DIAPH2,EZR,FAM101B,BCAR1,EMP2,TMSB15B,DPYSL3,SWAP70,FRY,PDLIM3,FRYL,DLG1,ARRB1,ESPN,TMOD2,CTTN,ARPC2,PACSIN1,SHROOM2,COBL |
| 1.884e-02 | -3.97 | QI_PLASMACYTOMA_DN | MSigDB lists | QI_PLASMACYTOMA_DN | 100 | 17 | 17758 | 1761 |
PVRL4,COL6A2,EPAS1,ST14,GNE,DNAJB11,RABGGTA,EPCAM,UBE2T,DDOST,PPP2R5A,LYPD3,P4HA2,BMP1,MYH14,ETV4,FARP2 |
| 1.884e-02 | -3.97 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | 100 | 17 | 17758 | 1761 |
CCNE2,FBXL16,GRHL2,ZNF395,LGR4,HOXB7,PHLPP1,B3GALNT1,RAB11FIP2,RBL1,ZNF367,DAPK1,RHOBTB2,DLG3,MAP3K5,MPHOSPH9,GCNT1 |
| 1.892e-02 | -3.97 | PEX19 (peroxisomal biogenesis factor 19) | protein interactions | 5824 | 114 | 20 | 16036 | 1726 |
MYO5B,B3GALT6,PSMB4,MOSPD2,ASPM,F11R,POMGNT1,ATP13A2,GLCE,TMEM54,ABHD12,FAM20B,GLB1L2,ABCD1,IQGAP3,FAR2,HSPB1,MYO5A,EGLN1,CD33 |
| 1.897e-02 | -3.97 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | 188 | 28 | 17758 | 1761 |
ENPP4,SCN5A,TNIP1,IL15RA,VANGL1,EPHA4,UBE2A,C6orf106,SNN,SAV1,SLC20A1,APPBP2,TAPBP,PSMD1,XYLT2,FAM20B,MITF,NR4A3,TRIOBP,RAB20,MANF,GDF11,PTPRE,ST3GAL1,IFIH1,MAFF,RASGRP1,EHD1 |
| 1.897e-02 | -3.97 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | 188 | 28 | 17758 | 1761 |
PPIF,PLK1,SYPL1,SERPINE2,FIGNL1,PBK,TMEM41B,HEATR5A,GPSM2,XRCC6BP1,CENPN,CMTM7,PRDX4,PRIM1,BTG3,UAP1,PRICKLE3,CYP2S1,RANBP1,PCYOX1,RYK,STK39,AHCY,SPCS3,NDFIP1,TIAM1,NR2C1,NUP85 |
| 1.897e-02 | -3.97 | GSE17721_LPS_VS_POLYIC_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDM_DN | 188 | 28 | 17758 | 1761 |
REC8,SIGIRR,SMARCA2,SORT1,TRIM8,HPS3,CAPN6,SELL,DIAPH2,CRABP2,SNTB1,ARHGEF40,MNS1,KIAA1161,ATP13A2,NUDT16,DNAJC10,ADD3,CA2,SLC16A6,SPINT2,PCYOX1,ARRDC1,LRRK1,CKAP4,KDELR1,USP43,ABCC1 |
| 1.897e-02 | -3.97 | GSE13306_RA_VS_UNTREATED_TREG_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_DN | 188 | 28 | 17758 | 1761 |
GAS2L1,PHF20L1,LASP1,CELSR2,CKAP2,GABRG2,CDCA2,NEURL1B,IL18R1,SIRPA,EPDR1,HDAC9,TMCC3,DTX3L,COL13A1,METTL7A,IMPAD1,FJX1,MITF,SECTM1,PPM1H,NLRC5,TMEM51,ZDHHC7,OSTF1,IGFBP2,GLCCI1,CDKN2D |
| 1.897e-02 | -3.97 | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | 188 | 28 | 17758 | 1761 |
GRN,SORBS1,GNPDA1,VANGL1,CAST,RC3H2,CCDC68,COX6C,SEPP1,DHRS3,ABCD4,OPTN,MFAP3L,PSMD1,MAP2,AKR1B1,VAT1,RPN2,CDK18,MDH1,MANF,EGLN3,MAST4,TRAM1,E2F8,CRTAP,CYP1B1,WBP5 |
| 1.897e-02 | -3.97 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | 188 | 28 | 17758 | 1761 |
SCN5A,MRC2,HSPG2,ATP8A1,CORO2A,NKRF,OAT,KIF11,TEAD3,BCAR3,TFAP4,GPRC5B,RAB11FIP2,RBL1,STIM1,DHRS2,NAT1,KIF14,DAPK1,CD9,SFMBT1,BUB1,DIXDC1,GDF11,PLOD3,PLCB2,ATP2B1,JARID2 |
| 1.897e-02 | -3.97 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | 188 | 28 | 17758 | 1761 |
ANXA3,LOC81691,NQO1,MTRF1L,KCTD12,FAM101B,NFIB,GPLD1,EPCAM,TAPBP,PTPRJ,IGF1R,MAP2,GATA2,TWSG1,WFS1,CSF1,MITF,TRPC1,NR4A2,FHL1,ZRANB1,SLC12A2,IFIH1,F2RL1,AHR,ABCG1,METAP2 |
| 1.898e-02 | -3.96 | HALLMARK_HEDGEHOG_SIGNALING | MSigDB lists | HALLMARK_HEDGEHOG_SIGNALING | 35 | 8 | 17758 | 1761 |
ETS2,SCG2,DPYSL2,TLE1,L1CAM,CDK5R1,NRP2,RASA1 |
| 1.898e-02 | -3.96 | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | MSigDB lists | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | 35 | 8 | 17758 | 1761 |
ITGA3,SERPINE2,GPRC5B,FTH1,SOX8,DNER,TSPAN7,HLA-A |
| 1.898e-02 | -3.96 | GNF2_RAP1B | MSigDB lists | GNF2_RAP1B | 35 | 8 | 17758 | 1761 |
JAK1,HLA-E,STK38,INPP5D,IQGAP1,HLA-F,CAB39,OSTF1 |
| 1.898e-02 | -3.96 | MARZEC_IL2_SIGNALING_DN | MSigDB lists | MARZEC_IL2_SIGNALING_DN | 35 | 8 | 17758 | 1761 |
CDKN2C,PDGFC,SESN3,CDKN1C,DAPK1,CDKN1B,SESN1,FAS |
| 1.898e-02 | -3.96 | PID_PI3KCI_AKT_PATHWAY | MSigDB lists | PID_PI3KCI_AKT_PATHWAY | 35 | 8 | 17758 | 1761 |
SLC2A4,AKT1,CASP9,CDKN1B,BCL2L1,MAP3K5,PRKACA,TBC1D4 |
| 1.898e-02 | -3.96 | HOUSTIS_ROS | MSigDB lists | HOUSTIS_ROS | 35 | 8 | 17758 | 1761 |
GCLM,TXN,SDC4,FTH1,XDH,PRDX4,GPX4,CYP1B1 |
| 1.898e-02 | -3.96 | HU_GENOTOXIC_DAMAGE_4HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_4HR | 35 | 8 | 17758 | 1761 |
TIMP2,PTTG1,CDC20,NEK2,AURKA,BUB1,ANLN,CKS2 |
| 1.900e-02 | -3.96 | Synthesis of PIPs at the plasma membrane | REACTOME pathways | R-HSA-1660499 | 33 | 8 | 8202 | 867 |
MTM1,PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,PIK3C2B,PIK3CD |
| 1.901e-02 | -3.96 | MODULE_568 | MSigDB lists | MODULE_568 | 70 | 13 | 17758 | 1761 |
LAMP2,B3GALT6,SYPL1,ATP1A1,PLSCR1,KCNN4,SLC25A13,TMX4,PARP4,IRF2,ASAH1,TRIB2,FRMD4B |
| 1.901e-02 | -3.96 | BOYLAN_MULTIPLE_MYELOMA_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_DN | 70 | 13 | 17758 | 1761 |
ARAP2,SLC37A1,NFKBIE,SH3BP1,AIM1,CTDSPL,DRAM1,PRKRA,CMPK2,LIFR,S100A13,S100A6,CCDC88A |
| 1.901e-02 | -3.96 | GnRH signaling pathway | KEGG pathways | hsa04912 | 91 | 17 | 6908 | 758 |
MAP3K3,PLA2G4A,CALM1,CALM3,ITPR2,ITPR3,ELK1,PRKACA,GNA11,CALM2,GNAS,ITPR1,MAPK11,CACNA1D,PLD1,PLCB2,MAPK12 |
| 1.901e-02 | -3.96 | GnRH signaling pathway | KEGG pathways | ko04912 | 91 | 17 | 6908 | 758 |
MAP3K3,PLA2G4A,CALM1,CALM3,ITPR2,ITPR3,ELK1,PRKACA,GNA11,CALM2,GNAS,ITPR1,MAPK11,CACNA1D,PLD1,PLCB2,MAPK12 |
| 1.903e-02 | -3.96 | embryonic skeletal system development | biological process | GO:0048706 | 128 | 21 | 16441 | 1675 |
SPEF2,RUNX2,GRHL2,HSPG2,HOXB7,TGFBR1,OSR2,HOXB2,SIX4,GNAS,FGFR2,HOXA9,BMP7,MEGF8,DLG1,TFAP2A,TWIST1,OSR1,MDFI,PCSK5,SULF2 |
| 1.905e-02 | -3.96 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | 116 | 19 | 17775 | 1757 |
SCN5A,PIK3R1,ARFGEF1,TP53,FTH1,NUCB2,IDH1,PHLDA1,ENDOD1,CDKN2C,DOPEY2,PTEN,ABCB1,PIK3CA,TUBG1,TAGLN2,NEB,IGSF3,ABCC1 |
| 1.906e-02 | -3.96 | STAT3 (signal transducer and activator of transcription 3 (acute-phase response factor)) | protein interactions | 6774 | 212 | 33 | 16036 | 1726 |
RUNX2,FOXM1,TRIP10,RET,MORC4,PDIA3,ERBB2,HLA-A,CCND1,IGF1R,GATA2,IL6ST,TBCD,RP2,SYK,SIRT1,HES1,NR3C1,NR4A1,STAT4,OGDHL,ERBB2IP,FOS,LEPR,PIAS3,IDE,JAK1,FGFR2,NMI,HDAC1,NFKBIZ,JAK3,CAPN1 |
| 1.912e-02 | -3.96 | Regulation of insulin secretion | REACTOME pathways | R-HSA-422356 | 80 | 15 | 8202 | 867 |
GNAS,SLC25A4,GNB5,IQGAP1,ITPR1,CACNA2D2,KCNS3,PRKAR2B,ITPR2,CACNA1D,ITPR3,SLC25A5,PRKACA,PLCB2,GNA11 |
| 1.914e-02 | -3.96 | cation binding | molecular function | GO:0043169 | 4106 | 452 | 16491 | 1673 |
ACACB,HSPG2,SLC25A13,ATP8A1,RET,CACNA2D2,LACTB2,SYTL4,PJA2,CA8,BARD1,LTBP3,ZNF275,NCS1,EPDR1,CALM2,WEE1,CYP1A1,ZNF823,STIM1,PRICKLE3,ZFP36,CABP1,CYP2S1,KLF3,STEAP2,AOX1,MARCH2,ZBTB18,RNF26,SMYD5,TIPARP,APOBEC3G,ERAP2,METAP2,ACVR1C,CDA,LOXL2,PIF1,GALNT7,MCFD2,RNF19B,ZFAND5,TP53I3,CYP4F3,POR,PRIM1,PIAS3,ENPP1,PLCG1,GDE1,PTER,LIMK1,GNPTAB,ATP7B,NKD1,PRDM5,BMP1,AGFG2,DHTKD1,TRAF5,FGD1,DDX58,NUAK1,ITGA6,CALB2,DGKQ,MTL5,S100A2,HPCAL4,PRRG4,RABGGTA,MECOM,MARCH8,GNS,ITGA3,ZNRF2,MEGF8,NEK2,CADPS2,CACNA1D,ZMYM1,PIKFYVE,MAST4,DGKG,MYLIP,SYTL3,RIMS2,PMPCB,ZNF84,MFI2,TBC1D8B,SALL4,CALM1,ATP8B3,ANTXR1,PCTP,JADE2,GNA11,DCP2,CYB5A,DGKH,MMP15,PRKAG2,TIMM8A,MATN2,S100A5,AGBL5,FGD6,PCDH19,NR4A2,DRP2,MAP3K5,IFIH1,ZNF502,XDH,ADAMTS16,EGLN1,EHD1,PLA2G4A,RNF224,REPS2,S100A11,GALNT12,THRA,RPS6KA1,IQGAP1,ATP2C2,TESK2,RNF182,FTH1,DDR1,CYP39A1,REPS1,ZFYVE9,ZNF385B,APOBEC3B,RCN1,APLP2,ACAP2,RNF220,ZNF75D,CDH1,ENPP5,PDE4D,MYT1,NR2C1,ENPP4,SEC23A,APOBEC3D,UTRN,PRKCQ,SLC11A2,ATP1B1,PYGO1,PKMYT1,XRCC6BP1,ATP10D,ZNF618,SP4,ZNF469,NIN,AMZ2,PDLIM3,NGFRAP1,STK26,ZNF704,EFCAB14,TRABD2A,KLF5,NR3C2,MAPK12,ATP9A,EFHD2,CYB561,APOBEC3H,NUCB2,DTX3L,PHF7,RNF128,ARSG,PTEN,MGAT4A,FAM20B,ZFAND4,ATP8B1,PLEKHF1,ADAM15,CNOT6L,NPTXR,TRIM62,S100A6,ADAMTS2,ARAP2,ARHGEF28,SHMT1,PLSCR1,LONRF3,ZC3H11A,RAPGEF2,GRIN1,FURIN,ZKSCAN2,BLVRA,NEURL1B,AIF1L,ARSK,GALNT3,CDK5RAP1,NUCB1,TIMP3,PLOD2,NR1D2,ACVRL1,SYT7,NR4A3,ERAP1,PGM2L1,ITGAV,LRRK1,FHL1,OSR1,ARSB,CYBRD1,MELK,ESYT2,TLL2,MYL9,UNKL,LTBP1,NMRK1,TRIM2,CNOT8,LMCD1,NENF,MGAT5B,HDAC6,DNER,TRIM68,HTR1D,PLS3,CHPF,ZFYVE16,RPS6KA2,NPNT,ZCCHC12,SIVA1,IMPAD1,MKRN3,PAPL,MYRIP,DDX59,S100A13,RASGRP1,SP5,CYP1B1,ZNF462,THRB,PCGF5,KCNIP3,TRIM8,ING1,MCTP1,CELSR2,IDH1,ZBTB7B,RHEB,KDM4D,DZIP1L,TRIM9,MAN2A2,CXXC4,PLCH1,NEIL1,ZNF114,KLF12,P4HA2,ZNF367,ZNF165,ADIPOR1,SP6,KLF11,MYL12B,CAPN1,CPPED1,NR2C2,PRKAA2,LASP1,PARP12,LMTK3,ARAP3,ZNF395,ZCCHC24,RASA2,CALM3,TEC,B4GALT4,PHLPP1,FBLN1,ZNF432,CA2,GATA2,FRAS1,LIMCH1,PIM1,ZRANB1,PLCB2,CYP26B1,CHSY3,PCDH1,TESK1,MGAT4B,ZNF320,GYLTL1B,PDE5A,RNF113A,NUBP1,STEAP1,AMDHD1,G2E3,CDK5R1,RASGRP2,FECH,GNAS,NUDT16,PHLPP2,ITGA7,CGREF1,PRPS2,P4HA3,ZDHHC7,EGFL7,YOD1,LTBP2,ZDBF2,RARG,RNF146,KLF7,LMO7,SLC25A24,UGP2,P3H2,CTDSPL,TP53,MORC4,COL18A1,OSR2,CYP26A1,SYTL2,ZNF687,SETDB2,CYP4F11,LMO4,ZDHHC12,LHX6,SRR,BCL6,ZDHHC23,VAT1,CDH3,ECE1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,CHP1,SULF2,MAP3K3,CPD,SIRT1,GCA,ZNF525,TIMP2,FIGNL1,S100A4,ACO1,GLO1,MYL12A,MAP3K6,DAG1,ATP13A2,JADE1,DUOX1,IDE,ATP1A1,MMP17,STK38,PEX2,ADAMTS14,OVOL1,ANXA9,SYT13,CYP2U1,LTA4H,AIFM3,ZNF701,GLIS3,ZMAT1,MAN2B2,ANXA3,FBLIM1,PINK1,ENO2,CDH22,CIT,LRP4,GNE,ERI2,TGFBR1,GTF3A,NRP2,PPP2R3A,HDAC9,ZDHHC21,IRF2BPL,TOP2A,FOXP2,TAF1B,MLPH,ALPP,GALNS,TRIM21,KLF9,ATP2B1,MYO5A,FAH,PHF20L1,PGM1,FBLN5,NR3C1,NR4A1,GCLC,AMFR,RC3H2,PPARA,MBNL3,OGDHL,PRICKLE1,RNPEP,DGKE,ENDOD1,SWAP70,FAT4,TRIM69,ZNF214,DTX4,PPP2R3C,GEM,PLOD3,ZMIZ1,ZBTB33 |
| 1.916e-02 | -3.95 | Wnt-protein binding | molecular function | GO:0017147 | 28 | 7 | 16491 | 1673 |
TRABD2A,CTHRC1,ROR1,FZD5,FZD4,FZD6,FZD7 |
| 1.917e-02 | -3.95 | DNA damage response | WikiPathways | WP707 | 67 | 14 | 4455 | 516 |
CCND1,CCNE2,DDB2,CASP3,CASP9,BAX,TP53,CDKN1B,RAD17,CCNB1,SESN1,CCNB2,CDK1,FAS |
| 1.924e-02 | -3.95 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | 180 | 27 | 17758 | 1761 |
EXPH5,LMO7,GFPT1,RASGRF1,PHF20L1,SPC25,ZNF395,NQO1,TSC22D3,EIF5A2,TRIB2,ITPR3,RASGRP2,PIAS3,MFAP3L,SLC6A6,PLK2,SETD3,PLK4,BCL6,DTX4,SORL1,CDH3,HSPB1,AHR,HIPK3,KLF7 |
| 1.924e-02 | -3.95 | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | 180 | 27 | 17758 | 1761 |
UGT8,UGP2,ADD1,BCL9,DGKQ,SELL,TNS1,EPHA1,DENND2D,SCML1,ATP1A1,ST5,AP1M2,IL6ST,SH3BP4,SORL1,CLMN,DIXDC1,KLF9,ECE1,RAP1GAP,TRAF5,PPP6R1,CRTAP,KLF7,TLL2,ABCC1 |
| 1.924e-02 | -3.95 | GCAAAAA,MIR-129 | MSigDB lists | GCAAAAA,MIR-129 | 180 | 27 | 17758 | 1761 |
SUN2,ITGA6,OXR1,PIK3R1,SLC25A27,NRG2,ETS1,SP4,VPS26A,SH3KBP1,LMNA,IRF2BPL,PLCG1,SP100,EFR3A,ANKS1B,FAM13B,BCL6,DUSP10,SFMBT1,PITPNA,NR4A2,DAB2IP,ACSL4,NR3C2,CBX7,NR2C2 |
| 1.924e-02 | -3.95 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS | 180 | 27 | 17758 | 1761 |
SYPL1,SGCE,SLC2A4,CAPN6,CHCHD7,PPARA,ARFGEF1,DNAJB11,NANS,SDC1,SPTLC2,FBLN1,RNF19B,AIP,RANBP9,ZFYVE16,TAPBP,HNRNPH2,MMP17,TPST1,AHCY,IFIT1,EPB41L4B,TIPARP,E2F8,ABCA1,PKIA |
| 1.924e-02 | -3.95 | REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | REGULATION_OF_DEVELOPMENTAL_PROCESS | 437 | 57 | 17758 | 1761 |
CASP3,ARAP3,DAP,TP53,BCL2L1,AIFM2,GSTP1,ETS1,BARD1,ADAMTSL4,HDAC9,IER3,TOP2A,CDKN2C,DAPK2,CARD8,ADORA1,IGF1R,PTEN,SIVA1,DAPK1,BAX,BCL6,CDKN1B,CD70,PIM1,F2R,CDKN2D,SOCS5,MX1,ACVR1C,GCLC,CASP9,HTATIP2,RUNX3,GLO1,NPHP3,BCAR1,STK17B,CDK1,CASP4,CDK5R1,RASA1,SOCS3,STK17A,FAS,SCG2,SEMA4D,MADD,FGD6,HDAC1,MAP3K5,AIFM3,HSPB1,IFI6,HIPK3,FGD1 |
| 1.926e-02 | -3.95 | SEIDEN_ONCOGENESIS_BY_MET | MSigDB lists | SEIDEN_ONCOGENESIS_BY_MET | 85 | 15 | 17758 | 1761 |
ANXA3,SEC23A,SLC25A24,PTEN,PLOD2,HNRNPH2,SH3BGRL,ITGA6,EPS8,MMADHC,NCKAP1,F2RL1,TRAM1,CDK1,PLS3 |
| 1.926e-02 | -3.95 | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | 85 | 15 | 17758 | 1761 |
PRSS8,CAMSAP3,AP1M2,ITGA3,CDH1,AASS,ETV5,EZR,PKP2,ALPK3,CTSZ,TAGLN2,EGLN3,CBX7,IER3 |
| 1.927e-02 | -3.95 | fatty acid metabolic process | biological process | GO:0006631 | 290 | 41 | 16441 | 1675 |
PLA2G4A,PRKAA2,ACACB,FAM213B,CPT2,MGST2,LPIN3,SGPL1,CYP1A1,SLC27A6,CYP2S1,ECI2,ABCD1,ACSL4,ACOX2,TECR,SYK,MYO5A,GPX4,CYP1B1,ABCC1,FADS2,ELOVL3,PPARA,PRKAR2B,RNPEP,POR,CYP4F3,MAPKAPK2,ALDH5A1,PRKAG2,ACADSB,FAAH,PEX2,SLC27A1,ADIPOR1,CYP2U1,LTA4H,SLC27A3,PTGES,ACOT7 |
| 1.931e-02 | -3.95 | GCTTGAA,MIR-498 | MSigDB lists | GCTTGAA,MIR-498 | 108 | 18 | 17758 | 1761 |
SPRED1,PACSIN2,RUNX2,TSC22D3,PIK3R1,ARL4C,MORF4L2,RAB6A,DUSP4,SIX4,SOCS3,KLF12,UBE2J1,AGBL5,IRF2,EPB41L4B,PDIA6,ATP2B1 |
| 1.938e-02 | -3.94 | KDM4D (lysine (K)-specific demethylase 4D) | protein interactions | 55693 | 6 | 3 | 16036 | 1726 |
CUL4B,TP53,KDM4D |
| 1.938e-02 | -3.94 | CHN2 (chimerin 2) | protein interactions | 1124 | 6 | 3 | 16036 | 1726 |
TGFBR1,ERBB3,AKT1 |
| 1.938e-02 | -3.94 | LAMB3 (laminin, beta 3) | protein interactions | 3914 | 6 | 3 | 16036 | 1726 |
PDIA3,COL7A1,BMP1 |
| 1.938e-02 | -3.94 | INSM1 (insulinoma-associated 1) | protein interactions | 3642 | 6 | 3 | 16036 | 1726 |
HDAC1,CCND1,SORBS1 |
| 1.938e-02 | -3.94 | Smurf2 (SMAD specific E3 ubiquitin protein ligase 2) | protein interactions | 66313 | 6 | 3 | 16036 | 1726 |
PTEN,ANKRD6,DVL2 |
| 1.938e-02 | -3.94 | PITPNM1 (phosphatidylinositol transfer protein, membrane-associated 1) | protein interactions | 9600 | 6 | 3 | 16036 | 1726 |
PLK1,RHOA,CDK1 |
| 1.938e-02 | -3.94 | NDST1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1) | protein interactions | 3340 | 6 | 3 | 16036 | 1726 |
CPEB4,HLA-E,PLAUR |
| 1.938e-02 | -3.94 | MEF2B (myocyte enhancer factor 2B) | protein interactions | 100271849 | 6 | 3 | 16036 | 1726 |
CABIN1,HDAC6,HDAC9 |
| 1.938e-02 | -3.94 | MYT1 (myelin transcription factor 1) | protein interactions | 4661 | 6 | 3 | 16036 | 1726 |
PLK1,HDAC1,CDK1 |
| 1.938e-02 | -3.94 | NEXN (nexilin (F actin binding protein)) | protein interactions | 91624 | 6 | 3 | 16036 | 1726 |
LGR4,HSPB1,CALM1 |
| 1.938e-02 | -3.94 | GRIN2C (glutamate receptor, ionotropic, N-methyl D-aspartate 2C) | protein interactions | 2905 | 6 | 3 | 16036 | 1726 |
DLGAP1,ERBB2IP,DLG3 |
| 1.938e-02 | -3.94 | FXYD7 (FXYD domain containing ion transport regulator 7) | protein interactions | 53822 | 6 | 3 | 16036 | 1726 |
ATP1A1,ATP1B1,APPBP2 |
| 1.938e-02 | -3.94 | SYTL5 (synaptotagmin-like 5) | protein interactions | 94122 | 6 | 3 | 16036 | 1726 |
RAB6A,CEP70,RAB27B |
| 1.938e-02 | -3.94 | Bace1 (beta-site APP cleaving enzyme 1) | protein interactions | 23821 | 6 | 3 | 16036 | 1726 |
BRI3,ATP1B1,RANBP9 |
| 1.940e-02 | -3.94 | cell cycle | biological process | GO:0007049 | 1319 | 157 | 16441 | 1675 |
SUN1,KLK10,CUL4B,NDC80,PSME1,CCNB1,VASH1,BARD1,CENPN,FANCI,CDKN2C,WEE1,PSMD1,CNTRL,CEP78,DLG1,TUBG1,PLK1,ING1,CENPA,PBK,EZR,PRKAR2B,KIF13A,CCNF,ANLN,SESN1,CDK1,RHEB,OPTN,PRIM1,PLK2,PRDM5,CAB39,HDAC1,KLF11,ARF6,E2F8,LZTS1,RRAGD,PRKAA2,HJURP,CDKN1C,KIF23,GPSM2,LMNA,C9orf69,SNX18,NEK2,PIM1,NUP85,CYP26B1,REC8,KIF20A,MYBL2,STRADB,HMG20B,PSMA4,RASA1,MAPKAPK2,PRKAG2,FAM64A,UTP14C,CGREF1,CDCA5,FAM83D,AURKA,NDE1,CCNB2,NUP58,CCNE2,GAS2L1,AVPI1,DLGAP5,CEP70,SPC25,FOXM1,ACTR8,PSME2,RPS6KA1,PTTG1,TP53,NUF2,TDRKH,BCL2L1,PRKACA,STIL,MNS1,IER3,CCND1,SETDB2,KIF14,PLK4,CDKN1B,DIXDC1,DAB2IP,CDKN2D,CKS2,SEPT6,CDC20,CDCA2,NUSAP1,PKMYT1,ERBB2IP,RAD17,RBL1,TRIOBP,OVOL1,RGS14,REEP4,PPP2R2D,MAPK12,NKX3-1,ARHGEF11,CKAP2,KLHL13,CIT,CENPI,EPS8,CDCA8,OSGIN2,PSMD10,TGFBR1,FBXO6,TIPRL,BEX2,SAC3D1,TOP2A,E2F7,LLGL2,PTEN,TRIM21,BUB1,IQGAP3,SPRY2,SUN2,ZWINT,RHOA,PSMB4,TACC1,ASPM,RGCC,DIAPH2,KIF11,BORA,DCTN6,ABCB1,CENPE,GPER1,GEM,CEP41,WDR62,NCAPG2,UBE2C,AHR,ESPL1,MELK |
| 1.941e-02 | -3.94 | regulation of cysteine-type endopeptidase activity | biological process | GO:2000116 | 224 | 33 | 16441 | 1675 |
CASP3,NKX3-1,RPS6KA1,DAP,RET,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,DAPK1,BAX,CDKN1B,WNT3A,EGLN3,CDKN2D,F2R,SIRT1,RHOA,AKT1,ACVR1C,PLAUR,CASP9,SLC11A2,POR,FAS,NGFRAP1,ARRB1,GPER1,MAP3K5,IFI6,XDH |
| 1.943e-02 | -3.94 | NAD-dependent histone deacetylase activity (H3-K14 specific) | molecular function | GO:0032041 | 11 | 4 | 16491 | 1673 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.943e-02 | -3.94 | intronic transcription regulatory region sequence-specific DNA binding | molecular function | GO:0001161 | 11 | 4 | 16491 | 1673 |
HSF2,GRHL2,NCOA2,BCL6 |
| 1.943e-02 | -3.94 | diacylglycerol kinase activity | molecular function | GO:0004143 | 11 | 4 | 16491 | 1673 |
DGKH,DGKG,DGKE,DGKQ |
| 1.943e-02 | -3.94 | histone deacetylase activity (H3-K14 specific) | molecular function | GO:0031078 | 11 | 4 | 16491 | 1673 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.948e-02 | -3.94 | GSE10325_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_DN | 172 | 26 | 17758 | 1761 |
SYBU,CR2,CD40,LHFPL2,ATP10D,CD83,HDAC9,ARHGAP24,BANK1,SWAP70,METTL7A,PLCG2,SLC2A6,SIPA1L1,OPN3,DTX4,RHOBTB2,DHTKD1,TLE1,TSPAN13,RFX5,LTA4H,CLIP2,SYK,GM2A,SMAGP |
| 1.954e-02 | -3.94 | FN3 | smart domains | SM00060 | 187 | 30 | 9131 | 997 |
PTPRU,EPHA4,VWA1,COL7A1,IL27RA,EPHA1,FNDC3A,MERTK,LEPR,COL12A1,NEO1,TRIM9,PTPRF,EPHA10,PTPRJ,IGF1R,IGSF9,VASN,FLRT3,AXL,IL6ST,ANKFN1,IL31RA,KIAA0319,SORL1,EPHB4,NCAM1,L1CAM,LIFR,IGDCC4 |
| 1.956e-02 | -3.93 | soft_tissue-smooth_muscle-leiomyosarcoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyosarcoma | 42 | 9 | 17775 | 1757 |
CDKN2C,SS18,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1 |
| 1.956e-02 | -3.93 | cervix-carcinoma | COSMIC cancer mutations | cervix-carcinoma | 42 | 9 | 17775 | 1757 |
CDKN2C,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 1.956e-02 | -3.93 | leiomyosarcoma | COSMIC cancer mutations | leiomyosarcoma | 42 | 9 | 17775 | 1757 |
CDKN2C,SS18,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1 |
| 1.957e-02 | -3.93 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045737 | 28 | 7 | 16441 | 1675 |
CCND1,PSMD10,PIM1,AKT1,PDGFB,STIL,RGCC |
| 1.957e-02 | -3.93 | negative regulation of response to biotic stimulus | biological process | GO:0002832 | 28 | 7 | 16441 | 1675 |
SIGIRR,IFIT1,NLRX1,ITCH,MICB,TSPAN6,TRAF3IP1 |
| 1.957e-02 | -3.93 | hippo signaling | biological process | GO:0035329 | 28 | 7 | 16441 | 1675 |
AMOTL2,CASP3,SAV1,FAT4,PJA2,TEAD3,DVL2 |
| 1.959e-02 | -3.93 | zinc ion binding | molecular function | GO:0008270 | 1151 | 138 | 16491 | 1673 |
UNKL,TRIM2,LMCD1,SYTL4,HDAC6,PJA2,CA8,BARD1,TRIM68,ZCCHC12,PRICKLE3,SIVA1,MKRN3,MARCH2,RNF26,MYRIP,S100A13,APOBEC3G,RASGRP1,ERAP2,THRB,PCGF5,TRIM8,ING1,CDA,RNF19B,ZFAND5,TP53I3,PIAS3,CXXC4,MAN2A2,TRIM9,ENPP1,NEIL1,PTER,LIMK1,BMP1,TRAF5,NR2C2,DDX58,LASP1,ZCCHC24,RABGGTA,MARCH8,CA2,ZNRF2,GATA2,LIMCH1,ZMYM1,ZRANB1,MYLIP,PMPCB,ZNF84,RNF113A,JADE2,G2E3,MMP15,S100A5,AGBL5,ZDHHC7,NR4A2,ZDBF2,DRP2,IFIH1,RARG,RNF146,KLF7,ADAMTS16,LMO7,RNF224,THRA,TP53,MORC4,RNF182,ZNF385B,APOBEC3B,RNF220,ZNF75D,SETDB2,ZDHHC12,LMO4,LHX6,ZDHHC23,VAT1,MYT1,NR2C1,CPD,SEC23A,APOBEC3D,UTRN,SLC11A2,GLO1,PYGO1,AMZ2,JADE1,IDE,PDLIM3,MMP17,PEX2,ADAMTS14,LTA4H,NR3C2,ZMAT1,MAN2B2,FBLIM1,ERI2,APOBEC3H,ZDHHC21,DTX3L,PHF7,RNF128,ALPP,ZFAND4,TRIM21,ADAM15,TRIM62,S100A6,PHF20L1,ADAMTS2,LONRF3,NR3C1,NR4A1,AMFR,RC3H2,PPARA,PRICKLE1,BLVRA,NEURL1B,RNPEP,NR1D2,TRIM69,ZNF214,DTX4,NR4A3,ERAP1,FHL1,ZMIZ1,TLL2 |
| 1.959e-02 | -3.93 | microtubule motor activity | molecular function | GO:0003777 | 76 | 14 | 16491 | 1673 |
KIF5B,DYNLRB1,KIFC2,KIF20A,KIF14,KIF13B,KLC3,KIF23,KIF1C,KIF13A,CENPE,DNAH3,KIF11,APPBP2 |
| 1.960e-02 | -3.93 | cellular modified amino acid metabolic process | biological process | GO:0006575 | 216 | 32 | 16441 | 1675 |
PLA2G4A,GCLM,CRYM,MGST2,GSTP1,SERINC2,PCYOX1,ALDH7A1,AHCY,EGLN3,CRTAP,CTH,PRODH,OPLAH,SHMT1,PLSCR1,GCLC,PANK1,ERO1A,GGH,GLO1,ICMT,IDH1,PRDX4,SLCO4A1,DUOX1,ALDH5A1,ABHD12,P4HA2,SLC27A1,OCLN,EGLN1 |
| 1.960e-02 | -3.93 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0031145 | 83 | 15 | 16441 | 1675 |
PLK1,PSMD1,PSMB4,CIT,PSME2,PTTG1,CDC20,NEK2,AURKA,PSMD10,PSME1,CCNB1,UBE2C,PSMA4,CDK1 |
| 1.961e-02 | -3.93 | - | gene3d domains | 1.25.10.30 | 6 | 3 | 9988 | 1080 |
ITPR2,ITPR3,ITPR1 |
| 1.961e-02 | -3.93 | - | gene3d domains | 2.60.40.720 | 6 | 3 | 9988 | 1080 |
RUNX3,RUNX2,TP53 |
| 1.962e-02 | -3.93 | embryonic organ morphogenesis | biological process | GO:0048562 | 282 | 40 | 16441 | 1675 |
CTHRC1,RUNX2,GRHL2,HSPG2,HOXB7,SOX9,TGFBR1,OSR2,NCKAP1,STIL,HOXB2,SIX4,FZD6,SETDB2,GATA2,BMP7,MEGF8,ALDH1A3,DLG1,TFAP2A,TWIST1,WNT3A,SPRY2,DVL2,MDFI,HES1,SPEF2,SCRIB,NPHP3,PRKRA,ABR,GNAS,FGFR2,PTK7,LRIG1,TBX18,NR4A3,OSR1,FZD5,RARG |
| 1.962e-02 | -3.93 | protein kinase A binding | molecular function | GO:0051018 | 41 | 9 | 16491 | 1673 |
DACT1,SOX9,ARFGEF1,EZR,PRKAR2B,PJA2,MYRIP,PRKACA,PKIA |
| 1.963e-02 | -3.93 | V$NFKB_Q6 | MSigDB lists | V$NFKB_Q6 | 247 | 35 | 17758 | 1761 |
LASP1,BMF,NDRG2,TRIB2,DDR1,HOXB2,SPTB,PRRG4,CYP26A1,IRF2BPL,CTGF,CYR61,RGS3,LMO4,CD70,RFX5,XKR8,SEMA3B,TNIP1,SLC11A2,ATP1B1,CD40,FOXD2,CD83,PTPRJ,BFSP1,SYT7,NFKBIA,RAP2C,UACA,FAM117A,SP6,ATP1B3,JAK3,PTGES |
| 1.963e-02 | -3.93 | V$PR_Q2 | MSigDB lists | V$PR_Q2 | 247 | 35 | 17758 | 1761 |
FBLIM1,CPEB4,PPM1J,CTDSPL,CACNA2D2,LTBP3,SIX4,PPP2R3A,WWP2,SCML1,RCN1,SESN3,SCNN1A,CTGF,FRY,RNF128,STIM1,ZNRF2,RGS3,KLF3,CDKN1B,PDE4D,DLG3,CAPN6,BCL9,PANK1,DGKH,ONECUT1,TMEM164,RBM47,NR4A3,SH3BP4,PGM2L1,LEMD1,SEMA3A |
| 1.966e-02 | -3.93 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | 63 | 12 | 17758 | 1761 |
HMMR,APOBEC3B,GFPT1,CASP3,UAP1,PPP1R2,UBE2J1,AURKA,FHL1,TRAM1,DNAJB9,PDIA4 |
| 1.966e-02 | -3.93 | GOLDRATH_IMMUNE_MEMORY | MSigDB lists | GOLDRATH_IMMUNE_MEMORY | 63 | 12 | 17758 | 1761 |
GOLIM4,SORBS1,IL15RA,CHCHD7,NR1D2,ABCB1,KCTD12,NCKAP1,TMEM159,F2R,DOCK9,MAPK12 |
| 1.966e-02 | -3.93 | BYSTROEM_CORRELATED_WITH_IL5_DN | MSigDB lists | BYSTROEM_CORRELATED_WITH_IL5_DN | 63 | 12 | 17758 | 1761 |
MAPKAPK2,PTPRJ,NR3C1,FOXM1,IL6ST,PIK3R1,SORL1,PIM1,PLD1,PIK3CD,TRAM1,SYK |
| 1.966e-02 | -3.93 | PPP3CA (protein phosphatase 3, catalytic subunit, alpha isozyme) | protein interactions | 5530 | 65 | 13 | 16036 | 1726 |
C16orf74,CASP3,KCNIP3,AKT1,PTEN,PHLPP2,TP53,GABRG2,IRF2,CABIN1,PDE4D,RCAN3,PDIA6 |
| 1.968e-02 | -3.93 | regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000045 | 144 | 23 | 16441 | 1675 |
PSMB4,AKT1,PSME2,CUL4B,CTDSPL,TP53,RGCC,PSMD10,PSME1,PSMA4,JADE1,CCND1,E2F7,CYP1A1,PSMD1,TJP3,PTEN,DACT1,KIF14,CDKN1B,FHL1,PIM1,CTDSP2 |
| 1.968e-02 | -3.93 | V$SREBP1_01 | MSigDB lists | V$SREBP1_01 | 164 | 25 | 17758 | 1761 |
GRN,LAMP1,SIRT1,HPS3,ARMCX3,ALDH6A1,HOXB7,OGDHL,FAM134A,CBX6,PKN1,TCEAL8,VPS26A,ABR,KLF12,NGFRAP1,HNRNPH2,FAM13B,BAX,SNX16,GLA,C1orf43,ARMCX6,DVL2,RNF146 |
| 1.968e-02 | -3.93 | PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | PROTEIN_COMPLEX_ASSEMBLY | 164 | 25 | 17758 | 1761 |
WASF3,REPS2,AASS,AMFR,TP53,CDA,TGFBR1,ANLN,CD40,APC2,NUBP1,RANBP9,DAG1,ZFYVE9,FAS,TAPBP,ALDH5A1,IGF1R,NOD2,BAX,CD9,HMGA1,TLN2,SYK,OCLN |
| 1.971e-02 | -3.93 | mucosal-associated lymphoid tissue development | biological process | GO:0048537 | 11 | 4 | 16441 | 1675 |
ARTN,CACNB4,FOXL1,RET |
| 1.971e-02 | -3.93 | positive regulation of collateral sprouting | biological process | GO:0048672 | 11 | 4 | 16441 | 1675 |
EFNA5,CRABP2,WNT3A,SEMA4D |
| 1.971e-02 | -3.93 | regulation of defense response to bacterium | biological process | GO:1900424 | 11 | 4 | 16441 | 1675 |
KLK7,KLK5,F2RL1,NOD2 |
| 1.971e-02 | -3.93 | negative regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014067 | 11 | 4 | 16441 | 1675 |
DAB2IP,TWIST1,SERPINE2,PTEN |
| 1.971e-02 | -3.93 | negative regulation of type 2 immune response | biological process | GO:0002829 | 11 | 4 | 16441 | 1675 |
IL27RA,NDFIP1,BCL6,SOCS5 |
| 1.971e-02 | -3.93 | Peyer's patch development | biological process | GO:0048541 | 11 | 4 | 16441 | 1675 |
ARTN,CACNB4,FOXL1,RET |
| 1.975e-02 | -3.92 | establishment of epithelial cell polarity | biological process | GO:0090162 | 22 | 6 | 16441 | 1675 |
EZR,MPP5,FRMD4A,ARF6,PTK7,FRMD4B |
| 1.975e-02 | -3.92 | Phospholipase C-mediated cascade; FGFR3 | REACTOME pathways | R-HSA-5654227 | 46 | 10 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 1.978e-02 | -3.92 | APOBEC_N | pfam domains | PF08210 | 11 | 4 | 16629 | 1696 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 1.978e-02 | -3.92 | Frizzled | pfam domains | PF01534 | 11 | 4 | 16629 | 1696 |
FZD5,FZD4,FZD7,FZD6 |
| 1.978e-02 | -3.92 | HlyIII | pfam domains | PF03006 | 11 | 4 | 16629 | 1696 |
ADIPOR1,MMD,PAQR5,PAQR7 |
| 1.978e-02 | -3.92 | Hist_deacetyl | pfam domains | PF00850 | 11 | 4 | 16629 | 1696 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 1.981e-02 | -3.92 | transferase activity, transferring glycosyl groups | molecular function | GO:0016757 | 275 | 39 | 16491 | 1673 |
UGT8,PARP12,GALNT12,XYLT1,HEXB,MGAT5B,POMGNT1,B4GALT4,CHPF,B4GALNT1,B3GALNT1,TYMP,FUT2,A4GALT,XYLT2,MGAT4A,ALG13,FUT8,FUT1,RPN2,TIPARP,MGAT5,PARP9,GCNT1,CHSY3,SIRT1,B3GALT6,B3GNT7,B3GNT2,MGAT4B,PARP4,GYLTL1B,C1GALT1C1,GALNT7,GLT8D2,GALNT3,DDOST,PLOD3,ST3GAL1 |
| 1.983e-02 | -3.92 | Renin secretion | KEGG pathways | ko04924 | 64 | 13 | 6908 | 758 |
GNAS,CALM2,ADORA1,ITPR1,CALM1,PTGER4,CALM3,ITPR2,CACNA1D,ITPR3,PLCB2,PRKACA,EDNRA |
| 1.983e-02 | -3.92 | Renin secretion | KEGG pathways | hsa04924 | 64 | 13 | 6908 | 758 |
GNAS,CALM2,ADORA1,ITPR1,CALM1,PTGER4,CALM3,ITPR2,CACNA1D,ITPR3,PLCB2,PRKACA,EDNRA |
| 1.986e-02 | -3.92 | CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 124 | 20 | 17758 | 1761 |
B3GALT6,GFPT1,GAA,UGP2,GNPDA1,GUSB,GNE,XYLT1,ACO1,PDK3,IDH1,GLCE,GNS,IRS2,HS6ST1,HPSE,UAP1,PTEN,HS3ST3B1,GAD1 |
| 1.986e-02 | -3.92 | inner ear morphogenesis | biological process | GO:0042472 | 98 | 17 | 16441 | 1675 |
CTHRC1,SOX9,SCRIB,SIX4,ABR,FZD6,FGFR2,GATA2,PTK7,LRIG1,TBX18,ALDH1A3,NR4A3,TFAP2A,WNT3A,SPRY2,DVL2 |
| 1.986e-02 | -3.92 | polyol metabolic process | biological process | GO:0019751 | 98 | 17 | 16441 | 1675 |
INPP5D,CALM1,CALM3,ISYNA1,SPTLC2,CALM2,PLCG1,PLCH1,PTEN,IMPAD1,PLCG2,INPP4B,AKR1B1,GOT1,ITPKA,MINPP1,PLCB2 |
| 1.988e-02 | -3.92 | DDENN | prosite domains | PS50947 | 16 | 5 | 11866 | 1235 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.988e-02 | -3.92 | SULFATASE_1 | prosite domains | PS00523 | 16 | 5 | 11866 | 1235 |
GNS,ARSB,ARSG,GALNS,SULF2 |
| 1.988e-02 | -3.92 | CYT_DCMP_DEAMINASES_2 | prosite domains | PS51747 | 16 | 5 | 11866 | 1235 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 1.988e-02 | -3.92 | DENN | prosite domains | PS50211 | 16 | 5 | 11866 | 1235 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.988e-02 | -3.92 | UDENN | prosite domains | PS50946 | 16 | 5 | 11866 | 1235 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 1.989e-02 | -3.92 | GSE20715_0H_VS_24H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_DN | 197 | 29 | 17758 | 1761 |
SORBS1,CDKN1C,FURIN,SCRIB,GDF15,BCL2L1,NPC2,DOCK5,MERTK,ADAMTSL4,MAP3K6,EFNB1,CARD10,ELF3,BCAR3,RBM47,KLF12,KCNK1,FABP6,PLK4,DAPK1,CDK18,SPCS3,KLF9,TINAGL1,MANF,MAFF,CTH,CKS2 |
| 1.989e-02 | -3.92 | GSE17721_CTRL_VS_POLYIC_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDM_DN | 197 | 29 | 17758 | 1761 |
GFPT1,GCA,LZTFL1,MFI2,CRYM,IGSF8,BCL2L1,ATP8B3,TRIB2,EDNRA,IER3,ENDOD1,PLCG1,ADORA1,SH3BP1,RND3,LMO4,ITPR1,RANBP1,SNX16,HDAC1,KLF5,CD70,MDFIC,HMGA1,CACNA1D,MAP3K5,PTPRE,E2F8 |
| 1.989e-02 | -3.92 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | 197 | 29 | 17758 | 1761 |
BIN1,CMAS,LASP1,B3GNT2,TNIP1,S100A11,TBC1D1,PLEKHO1,TAP1,TP53,IL27RA,ALCAM,SLC20A1,CMTM6,C3orf58,SIRPA,COL12A1,CMTM7,IRS2,C16orf74,CDKN2C,ADRBK1,KLF3,NEK2,BRI3,ABCD1,TAGLN2,ERBB3,MAFF |
| 1.990e-02 | -3.92 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | 222 | 32 | 17758 | 1761 |
LASP1,RALBP1,TSC22D3,INPP5D,RPS6KA1,IQGAP1,LBR,DAPK2,ADD3,ADRBK1,PLCG2,CITED2,PHKA2,CDKN2D,PLCB2,MAP3K3,GCA,SMARCA2,AKT1,HTATIP2,ARHGDIB,RASA1,RASGRP2,GNAS,GALNT3,JAK1,STK38,PRCP,RGS14,MAP3K5,TOB1,ABCG1 |
| 1.991e-02 | -3.92 | Phenytoin (Antiarrhythmic) Action Pathway | SMPDB pathways | SMP00327 | 77 | 17 | 978 | 131 |
SCN5A,NQO1,SNTB2,CALM1,CACNA2D2,DNAJB11,ATP1B1,SNTB1,ERP29,PRKACA,PDIA4,SNTA1,ATP1A1,KCNK1,ITPR1,ATP1B3,PDIA6 |
| 1.994e-02 | -3.92 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 307 | 42 | 17758 | 1761 |
CCNE2,CASP3,CDK17,TAP1,PDCL,DNAJB9,WEE1,BTG3,CTGF,SP100,CYR61,ZFP36,BCL6,PLK4,TRIM21,TRPC1,IFIT1,PDE4D,TIPARP,LOC81691,ZWINT,CD55,PLSCR1,IFITM3,NR3C1,ITCH,IFIT3,STK17B,STX3,GABARAPL1,DCTN6,RAB11FIP2,RND3,NR1D2,H1F0,DHRS2,NFKBIA,NMI,NR4A2,IRF7,GEM,IFI6 |
| 1.994e-02 | -3.91 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | 42 | 9 | 17758 | 1761 |
SERPINE2,NLRX1,PTTG1,GTF3A,BUB1,MANF,SLC25A5,S100A6,RASGRP2 |
| 1.994e-02 | -3.91 | ZUCCHI_METASTASIS_DN | MSigDB lists | ZUCCHI_METASTASIS_DN | 42 | 9 | 17758 | 1761 |
SEC61B,RHOA,LGALS3,CST3,SAT1,NFKBIA,CLDN4,TACSTD2,SEMA3B |
| 1.994e-02 | -3.91 | HARRIS_BRAIN_CANCER_PROGENITORS | MSigDB lists | HARRIS_BRAIN_CANCER_PROGENITORS | 42 | 9 | 17758 | 1761 |
COL6A2,PAPSS2,S100A4,COL6A1,AOX1,DHRS3,CASP4,SRPX2,S100A6 |
| 1.994e-02 | -3.91 | AMIT_EGF_RESPONSE_120_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_120_MCF10A | 42 | 9 | 17758 | 1761 |
TESK1,PLAUR,ALDH1A3,BAX,TRIM21,GDF15,PHLDA1,MAFF,GPR161 |
| 1.994e-02 | -3.91 | RASHI_RESPONSE_TO_IONIZING_RADIATION_1 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_1 | 42 | 9 | 17758 | 1761 |
SEC23A,FAM46A,TIMM8A,ZFP36,SGK1,SERPINB6,FOS,IER3,WWP2 |
| 1.996e-02 | -3.91 | protein maturation | biological process | GO:0051604 | 274 | 39 | 16441 | 1675 |
CASP3,NKX3-1,TSPAN15,DAP,RET,CTSZ,AIP,ATG4A,CARD8,CTSC,BAX,SORL1,CDKN1B,ECE1,LGMN,EGLN3,F2R,METAP2,ATG4D,CPD,PMPCB,ADAMTS2,CASP9,ERO1A,FURIN,SLC11A2,KLK6,F12,TYSND1,FAS,PRDX4,IDE,NGFRAP1,WFS1,CTSV,SPCS3,CAPN1,PCSK5,XDH |
| 1.996e-02 | -3.91 | extrinsic component of plasma membrane | cellular component | GO:0019897 | 131 | 21 | 17570 | 1756 |
SERPINE2,ST14,IQGAP1,TEC,YES1,APC2,GNA11,SYTL2,EPN3,GNAS,JAK1,CDH1,SNX18,CDK16,ARRB1,JAK3,TIAM1,SYTL3,SYK,S100A6,ESYT2 |
| 1.998e-02 | -3.91 | TBK1 (TANK-binding kinase 1) | protein interactions | 29110 | 93 | 17 | 16036 | 1726 |
DDX58,HMMR,NLRP4,MBP,TNIP1,AKT1,IFIT3,STX3,OPTN,SOCS3,NFKBIA,DTX4,IRF7,PPP6R1,SYK,NCOA2,TMEM173 |
| 1.998e-02 | -3.91 | IRS4 (insulin receptor substrate 4) | protein interactions | 8471 | 93 | 17 | 16036 | 1726 |
BIN1,PINK1,LGR4,CUL4B,PIK3R1,TP53,ERBB2,SAV1,LGALS3BP,RCN1,IGF1R,PTEN,P4HA2,PIK3CA,AURKA,TUBG1,HSPB1 |
| 1.999e-02 | -3.91 | CELL_PROLIFERATION_GO_0008283 | MSigDB lists | CELL_PROLIFERATION_GO_0008283 | 500 | 64 | 17758 | 1761 |
TXN,NF2,IL15RA,IL15,S100A11,CNOT8,TP53,ERBB2,COL18A1,IL18,FTH1,CD274,TP53I11,STIL,EMP2,TNFSF9,CDKN2C,PDGFA,BTG3,ARTN,IL31RA,ELF5,FABP6,DLG1,IRF2,TACSTD2,EPHB4,CDKN2D,CKS2,LAMP3,PLK1,ING1,PRKRA,SESN1,PGF,KLF11,GAB1,CAPN1,BIN1,CDKN1C,IGFBP6,EPS8,TGFBR1,ETS1,CTNNBIP1,IGF1R,CYR61,PTEN,BUB1,CD70,PIM1,SYK,CCDC88A,EIF5A2,RUNX3,BCAR1,CDK5R1,SCG2,ACVRL1,CSF1,CGREF1,ICOSLG,TOB1,CD33 |
| 2.001e-02 | -3.91 | cellular lipid catabolic process | biological process | GO:0044242 | 160 | 25 | 16441 | 1675 |
CYP26B1,PLA2G4A,CPT2,HEXB,LPIN3,PRKACA,CYP4F3,CYP26A1,SGPL1,PLCG1,ACADSB,ABHD12,FAAH,PEX2,PLCG2,FABP6,ECI2,ABCD1,PLD1,GLA,ACOX2,NAGA,GM2A,ACOT7,CYP1B1 |
| 2.004e-02 | -3.91 | ATPASE_ACTIVITY_COUPLED | MSigDB lists | ATPASE_ACTIVITY_COUPLED | 93 | 16 | 17758 | 1761 |
PEX6,RALBP1,ABCG2,DHX8,PIF1,ATP1B1,ABCD4,TOP2A,TAPBP,ATP1A1,ATP7B,ATP8B1,ATP1B3,ATP2B1,ABCG1,ABCC1 |
| 2.010e-02 | -3.91 | REACTOME_REGULATION_OF_APOPTOSIS | MSigDB lists | REACTOME_REGULATION_OF_APOPTOSIS | 56 | 11 | 17758 | 1761 |
DAPK2,CASP3,PSMD1,PSMB4,PSME2,CASP9,DAPK1,PSMD10,PSME1,UNC5B,PSMA4 |
| 2.010e-02 | -3.91 | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | 56 | 11 | 17758 | 1761 |
GNS,TAPBP,ALDH2,SEMA4D,AIM1,ITGAV,RGS14,CD40,SERPINB1,CAPN1,CD83 |
| 2.010e-02 | -3.91 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | 56 | 11 | 17758 | 1761 |
BCAR3,SYPL1,SWAP70,ALDH5A1,MMD,DBI,AES,CD40,ETS1,TRAF5,GSTP1 |
| 2.010e-02 | -3.91 | human chr2q37.1 | chromosome location | human chr2q37.1 | 48 | 8 | 26250 | 1887 |
PSMD1,HJURP,SP100,INPP5D,ARL4C,CAB39,C2orf72,LOC151475 |
| 2.011e-02 | -3.91 | regulation of ossification | biological process | GO:0030278 | 176 | 27 | 16441 | 1675 |
CTHRC1,RUNX2,SOX9,ANO6,LRP4,PTGER4,OSR2,PRKACA,FAM101B,DHRS3,BMP2K,CTNNBIP1,GNAS,ENPP1,CYR61,NPNT,FGFR2,SEMA4D,TWSG1,IL6ST,BMP7,CSF1,TFAP2A,SUCO,TWIST1,OSR1,TOB1 |
| 2.011e-02 | -3.91 | positive regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043123 | 176 | 27 | 16441 | 1675 |
MAP3K3,PINK1,TRIM8,RHOA,RIPK2,S100A4,LITAF,IL18,PRKCQ,CD40,TNFRSF19,SLC20A1,IL18R1,GPRC5B,PELI2,PLK2,TSPAN6,SECTM1,NOD2,SLC44A2,NDFIP1,F2R,F2RL1,TRAF5,S100A13,TRIM62,CTH |
| 2.011e-02 | -3.91 | lung development | biological process | GO:0030324 | 176 | 27 | 16441 | 1675 |
THRB,HES1,ADAMTS2,GRHL2,EPAS1,THRA,SOX9,RC3H2,CTSZ,GPSM2,SAV1,NPHP3,NFIB,DAG1,CRISPLD2,PDGFA,TNS3,HS6ST1,ITGA3,CTGF,FGFR2,PTK7,TMBIM6,PDE4D,PLOD3,LTA4H,SPRY2 |
| 2.011e-02 | -3.91 | TGCACTG,MIR-148A,MIR-152,MIR-148B | MSigDB lists | TGCACTG,MIR-148A,MIR-152,MIR-148B | 290 | 40 | 17758 | 1761 |
RMND5A,LTBP1,RUNX2,CPEB4,RALBP1,ETV5,ARFGEF1,C5orf30,PDIA3,SNN,DNER,LBR,SIX4,E2F7,MGAT4A,FAM13B,MITF,ELF5,FOSB,MAP3K9,MDFIC,ERBB3,MARCH2,BTBD3,PPP6R1,TRAK2,CPD,MMD,STRADB,MUM1L1,STX3,CDK5R1,PRKAG2,GPRC5B,CDK19,CSF1,BMP1,ABCA1,RGMA,SNPH |
| 2.011e-02 | -3.91 | response to alcohol | biological process | GO:0097305 | 316 | 44 | 16441 | 1675 |
GRN,CASP3,NKX3-1,SLC2A4,NQO1,IL15,EPS8,CALM3,TGFBR1,ITPR2,BCL2L1,PDGFB,ETS1,CALM2,CCND1,TFAP4,CDH1,CTGF,PTEN,BMP7,CST3,FOSB,BAX,CDKN1B,IGFBP2,KLF9,PIM1,CDKN2D,RHOA,CALM1,CASP9,GRIN1,GGH,ELK1,FOS,GPLD1,SOCS3,FECH,MMP15,NCOA3,MAP2,AURKA,HOXB13,GPER1 |
| 2.012e-02 | -3.91 | extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:0097192 | 41 | 9 | 16441 | 1675 |
CASP3,CASP9,DAPK1,BAX,ERBB3,ITGAV,BCL2L1,UNC5B,FAS |
| 2.012e-02 | -3.91 | signal transduction in absence of ligand | biological process | GO:0038034 | 41 | 9 | 16441 | 1675 |
CASP3,CASP9,DAPK1,BAX,ERBB3,ITGAV,BCL2L1,UNC5B,FAS |
| 2.012e-02 | -3.91 | positive regulation of cell-matrix adhesion | biological process | GO:0001954 | 41 | 9 | 16441 | 1675 |
EPB41L5,PTPRJ,FMN1,CSF1,SDC4,UTRN,EPHA1,EMP2,COL16A1 |
| 2.012e-02 | -3.91 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 792 | 96 | 17775 | 1757 |
LTBP1,GAA,NCKAP5,CRYM,SLC25A13,ATP8A1,TP53,DHX8,TEX2,RNF182,NUF2,SLC7A2,DNER,TMC1,ZNF385B,PLS3,CDKN2C,NKAIN3,ST5,SHC3,DPYSL2,ANKFN1,IL31RA,ATRNL1,NTN4,LGMN,LRP11,SLC39A10,CPD,MCTP1,USP18,SYNE2,UTRN,ACO1,ROR1,LDB2,SESN1,IDE,BFSP1,POPDC3,TRAF3IP1,TLE1,EFNA5,SERPINI1,TANC2,GAB1,FRMD4A,ZCCHC24,UBASH3B,MTL5,PBX3,CNTNAP2,ATG4A,CA2,IGF1R,ANKS1B,GATA2,FRAS1,CALD1,BDH1,GALNS,SORL1,CADPS2,HLA-C,CACNA1D,SYTL3,MYO5A,KDELR1,PDGFC,ARHGEF28,HPS3,MOSPD2,NUB1,SYBU,CXorf57,DIAPH2,MAML2,VEZT,LRRC1,NPHP3,PDIK1L,C3orf58,NFIB,STX3,CACHD1,PLEKHH2,PRKAG2,SWAP70,MAMDC4,SYT7,PPM1H,FGD6,CABIN1,GRAMD1C,MAP3K5,SEMA3A |
| 2.015e-02 | -3.90 | DLG1 (discs, large homolog 1 (Drosophila)) | protein interactions | 1739 | 86 | 16 | 16036 | 1726 |
DLGAP1,KCNJ12,SCN5A,FZD4,PBK,EZR,CALM3,LRRC1,FZD7,PTEN,KIF13B,DLG1,MARCH2,DLG3,WNT3A,MAPK12 |
| 2.016e-02 | -3.90 | GRADE_COLON_CANCER_UP | MSigDB lists | GRADE_COLON_CANCER_UP | 817 | 99 | 17758 | 1761 |
LAMP1,GAA,TXN,S100A11,CD82,COL18A1,PSME1,NENF,PLXNA1,MORF4L2,FAM101B,TRIM68,BCAP31,EPS8L2,CHPF,RAD23A,IER3,RCN1,ZDHHC12,CYP2S1,ABCA2,GLB1L2,CTTN,TECR,ETV4,MGAT5,GPX4,CKS2,SEPHS1,PPIF,ORAI2,SEC61B,CDC20,TNS1,RAD17,ITPR3,POR,PIAS3,TAPBP,DDOST,GRN,CD99,CD63,ITGA6,DCAF7,SOX9,CYB561,NDUFA4,GTF3A,PKN1,GSTP1,TTYH3,RABGGTA,PDIA4,TOP2A,DAZAP1,ADD3,ADRBK1,GATA2,CDK16,KCNN4,ATP5H,MEGF8,VASN,A4GALT,RANBP1,FXYD5,FAM102A,TMBIM6,ADAM15,CD70,TNFRSF12A,TAGLN2,SLC12A2,GAD1,MCCC2,S100A6,PVRL4,TGIF1,PCDH1,MFI2,PSMB4,BTNL9,PARP4,SPATA13,SCRIB,NUCB1,SLCO4A1,SLC6A6,HNRNPH2,NMI,HMGA1,PLOD3,ARPC2,UBE2C,USF2,IFI6,OCLN,ESYT2 |
| 2.017e-02 | -3.90 | FER (fer (fps/fes related) tyrosine kinase) | protein interactions | 2241 | 21 | 6 | 16036 | 1726 |
ERBB2,CTTN,ERBB3,CDH1,JAK1,CALM1 |
| 2.017e-02 | -3.90 | PI4KA (phosphatidylinositol 4-kinase, catalytic, alpha) | protein interactions | 5297 | 21 | 6 | 16036 | 1726 |
HLA-B,PITPNA,TGOLN2,CD274,HLA-C,MRPL44 |
| 2.017e-02 | -3.90 | TMEM51 (transmembrane protein 51) | protein interactions | 55092 | 21 | 6 | 16036 | 1726 |
SUSD3,WWP1,FNDC3A,PTER,ITCH,HSPA12A |
| 2.017e-02 | -3.90 | cellular response to hypoxia | biological process | GO:0071456 | 121 | 20 | 16441 | 1675 |
SIRT1,PINK1,NKX3-1,SLC2A4,AKT1,EPAS1,TP53,RGCC,SLC11A2,PDK3,CCNB1,LMNA,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,CPEB2,EGLN1 |
| 2.017e-02 | -3.90 | regulation of wound healing | biological process | GO:0061041 | 121 | 20 | 16441 | 1675 |
ENPP4,SERPINE2,PLAUR,UBASH3B,ANO6,ARFGEF1,PRKCQ,TEC,F12,PDGFB,CD109,PDGFA,HPSE,FAM46A,PLPP3,PRKG1,TNFRSF12A,F2RL1,F2R,SYK |
| 2.018e-02 | -3.90 | UBE2H (ubiquitin conjugating enzyme E2H) | protein interactions | 7328 | 79 | 15 | 16036 | 1726 |
CD99,MARCH8,DTX3L,JADE1,TRIM2,RNF128,UBASH3B,MKRN3,TRIM21,GOT1,MARCH2,LACTB2,HDAC6,IDH1,RNF146 |
| 2.023e-02 | -3.90 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | 189 | 28 | 17758 | 1761 |
SUSD3,CPD,UGT8,RUNX2,TTC39B,NFKBIE,FOXM1,ARMC7,LRRC66,LITAF,DIAPH2,TMCC3,GABARAPL1,RASGRP2,DAPK2,WEE1,CDH1,CTSC,ISM1,IQCE,NR4A3,ZDHHC23,RAB20,RCAN3,F2RL1,AHR,FGD1,CYP1B1 |
| 2.023e-02 | -3.90 | GSE27786_LSK_VS_NKTCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKTCELL_UP | 189 | 28 | 17758 | 1761 |
HMMR,PLK1,SYPL1,MCTP1,ADCK3,FLYWCH2,SLC25A13,LRRC66,KCTD12,CDCA2,TEX2,RNF113A,ZFAND5,ERP29,PRDX4,ATP13A2,MESDC2,METTL7A,MATN2,BRI3,AURKA,MLKL,PHKA2,CMPK2,PTPRE,DGKG,COL16A1,MCCC2 |
| 2.023e-02 | -3.90 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | 189 | 28 | 17758 | 1761 |
HPS3,ARMCX3,RAPGEF2,MCFD2,FNDC3A,ALCAM,ATP10D,RANBP9,CRISPLD2,DNAJB9,FRMD4B,SOCS3,AMZ2,CD109,PTPRJ,ITGA3,KIAA1107,TWSG1,ITGA7,ZFP36,N4BP3,PAPSS1,ATRNL1,GEM,MAP3K5,EGLN3,ABCA1,S100A6 |
| 2.023e-02 | -3.90 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | 189 | 28 | 17758 | 1761 |
ALDH6A1,ATP8A1,LRRC66,ARL4C,SELL,PDE5A,TCF7,SNN,FOS,ATP10D,CYP39A1,RASA1,TMCC3,NFIX,FOXD2,MID1IP1,RPS6KA2,FRY,SLC44A1,SLC44A2,MAPK11,HS3ST3B1,USF2,C9orf72,NIPA1,ATP2B1,MCCC2,KLF7 |
| 2.023e-02 | -3.90 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_DN | 189 | 28 | 17758 | 1761 |
CPD,GCA,RUSC2,RASA2,DNAJB11,FAM81A,PJA2,REPS1,RPS6KA2,ARTN,DPYSL2,HOXA9,LMO4,PLK2,AGBL5,SNX16,HDAC1,KLF5,CD70,MAPK11,MDFIC,TAGLN2,CACNA1D,ICOSLG,EGLN3,MYBL1,TRAF5,AHR |
| 2.023e-02 | -3.90 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | 189 | 28 | 17758 | 1761 |
ANXA3,TGIF1,B3GNT2,ENO2,PLSCR1,STAT4,DNAJB2,PIK3R1,LITAF,FHDC1,PDIA5,FTH1,PTGFRN,FAM46C,CASP4,STX3,LMNA,ARF4,CD83,M6PR,ONECUT1,TIMM8A,IMPAD1,PLK2,ADAM15,LGMN,PTGES,PCSK5 |
| 2.023e-02 | -3.90 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | 189 | 28 | 17758 | 1761 |
PGM1,ZWINT,SPC25,DLGAP5,FOXM1,PBK,PTGER4,KIF23,GGH,GPSM2,DUSP4,CCNF,PHLDA1,FZD6,FRMD4B,PLS3,APOBEC3B,FAM64A,RGS3,P4HA2,NETO2,AURKA,ESPL1,E2F8,RASGRP1,FAM69A,CTH,CKS2 |
| 2.023e-02 | -3.90 | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | 189 | 28 | 17758 | 1761 |
GFPT1,RMND5A,CMAS,HJURP,TBC1D8B,MRPS15,SEPT6,MRS2,TFAP2C,VEZT,GALNT7,KIF11,C11orf95,CENPN,RANBP9,PSMD1,HSF2,PPP2R5A,TAF1B,FAM189A1,SLC16A6,PLCG2,SRR,STK39,RP2,TOB1,EGLN1,TMEM131 |
| 2.024e-02 | -3.90 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | 49 | 10 | 17758 | 1761 |
FGFR2,ZFP36,COL6A1,LTBP2,DDR1,FOS,SLC12A2,CRTAP,FAS,CYP1B1 |
| 2.024e-02 | -3.90 | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | MSigDB lists | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | 49 | 10 | 17758 | 1761 |
MAPKAPK2,RPS6KA2,RIPK2,RPS6KA1,NOD2,MAPK11,DUSP4,ELK1,FOS,CDK1 |
| 2.024e-02 | -3.90 | WONG_PROTEASOME_GENE_MODULE | MSigDB lists | WONG_PROTEASOME_GENE_MODULE | 49 | 10 | 17758 | 1761 |
PSMD1,UBE2Q2,PSMB4,UBE2T,USP18,CDC20,PSMD10,PSME1,UBE2C,PSMA4 |
| 2.024e-02 | -3.90 | STARK_HYPPOCAMPUS_22Q11_DELETION_UP | MSigDB lists | STARK_HYPPOCAMPUS_22Q11_DELETION_UP | 49 | 10 | 17758 | 1761 |
CNTNAP1,SORT1,ADRBK1,CPEB4,EPAS1,EFR3A,FJX1,KBTBD11,CDK5R1,ATP13A2 |
| 2.024e-02 | -3.90 | MORI_IMMATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_UP | 49 | 10 | 17758 | 1761 |
GRN,GNS,ATP6V0B,TAPBP,SEMA4D,CD40,RGS14,CAPN1,JARID2,CD83 |
| 2.024e-02 | -3.90 | YANG_BREAST_CANCER_ESR1_LASER_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_LASER_DN | 49 | 10 | 17758 | 1761 |
SGCE,UGT8,KIF14,ARL4C,UBE2J1,PLD1,GSTP1,CYP39A1,PLS3,ARHGEF4 |
| 2.036e-02 | -3.89 | CXCR4 (chemokine (C-X-C motif) receptor 4) | protein interactions | 7852 | 39 | 9 | 16036 | 1726 |
HLA-B,JAK1,ITCH,SDC4,MYBL2,JAK3,ADRBK2,ATP13A2,SOCS3 |
| 2.046e-02 | -3.89 | Melanoma | KEGG pathways | hsa05218 | 71 | 14 | 6908 | 758 |
PDGFA,CCND1,PDGFC,AKT1,IGF1R,CDH1,PTEN,MITF,PIK3R1,TP53,PIK3CA,PIK3CD,PDGFB,FGF19 |
| 2.046e-02 | -3.89 | Melanoma | KEGG pathways | ko05218 | 71 | 14 | 6908 | 758 |
PDGFA,CCND1,PDGFC,AKT1,IGF1R,CDH1,PTEN,MITF,PIK3R1,TP53,PIK3CA,PIK3CD,PDGFB,FGF19 |
| 2.047e-02 | -3.89 | Oxytocin signaling pathway | KEGG pathways | ko04921 | 157 | 26 | 6908 | 758 |
PLA2G4A,PRKAA2,MYL9,KCNJ12,RHOA,CAMKK1,CALM1,PIK3R1,CACNA2D2,CALM3,ITPR2,CAMK1D,ITPR3,ELK1,CACNB4,PRKACA,FOS,GNAS,CCND1,CALM2,PRKAG2,ITPR1,PIK3CA,CACNA1D,PIK3CD,PLCB2 |
| 2.047e-02 | -3.89 | Oxytocin signaling pathway | KEGG pathways | hsa04921 | 157 | 26 | 6908 | 758 |
PLA2G4A,PRKAA2,MYL9,KCNJ12,RHOA,CAMKK1,CALM1,PIK3R1,CACNA2D2,CALM3,ITPR2,CAMK1D,ITPR3,ELK1,CACNB4,PRKACA,FOS,GNAS,CCND1,CALM2,PRKAG2,ITPR1,PIK3CA,CACNA1D,PIK3CD,PLCB2 |
| 2.051e-02 | -3.89 | establishment of protein localization | biological process | GO:0045184 | 1303 | 155 | 16441 | 1675 |
LAMP1,EXPH5,ARFGEF1,TAP1,F11R,MPP5,SYTL4,HDAC6,NUP62CL,ERP29,ZFYVE16,RAB15,AP1M2,NPNT,SNX16,RAB20,RP2,CTTN,PACSIN1,TRAM1,MYRIP,S100A13,PLK1,LAMP2,EZR,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,ARF4,OPTN,UEVLD,GNPTAB,RAB11FIP1,NOD2,ARF6,F2RL1,NXT2,PCSK5,GGA1,PEX6,RAB23,RAB6A,FAM21C,LMNA,ATG4A,DOPEY2,SNX18,RINL,FRAS1,KIF13B,RPL39,EXOC8,SORL1,CADPS2,SYTL3,NUP85,RIMS2,SNX7,KDELR1,TRAK2,PMPCB,KIF20A,BTN3A2,STRADB,STX3,GNAS,SCARB2,AP1AR,TIMM8A,NFKBIA,ZDHHC7,CTSA,LTBP2,HOOK1,JAK3,TOB1,NUP58,SNX30,EHD1,MTM1,TP53,C5orf30,PKP2,MVB12B,BCAP31,SYTL2,APPBP2,ZFYVE9,ATP6V0B,SVBP,CDH1,KIF14,ZDHHC12,REEP1,ZDHHC23,BCL6,RPN2,IFIT1,RAB27B,ARL4D,LMAN1,SNX10,F2R,CHP1,ATG4D,MYO5B,SEC23A,SEC61B,AKT1,COG2,SLC11A2,RAB38,ATP1B1,DAG1,ATP10D,SNX12,DDOST,CORO1C,PEX2,ABCA1,TTC8,PINK1,CD63,TSPAN15,PDIA3,BTN3A1,AIP,VPS26A,ZDHHC21,PDIA4,MLPH,ADORA1,RRBP1,BAX,SYK,MYO5A,HES1,RAB3B,LCA5,EIF5A2,PIK3R1,PRICKLE1,NEURL1B,BBS2,RPL12,MAMDC4,SCG2,RAB11FIP2,ARRB1,SPCS3,CEP41,RAB3IL1,ABCG1 |
| 2.054e-02 | -3.89 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 1634 | 191 | 16441 | 1675 |
LGR4,EPAS1,DNAJC3,HEXB,RET,ARFGEF1,MORF4L2,CAMK1D,HDAC6,PDGFB,EPCAM,HSF2,CTGF,GRHL1,NPNT,IL31RA,MITF,FOSB,PASK,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,AHRR,MDK,KLF12,NOD2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,IGF1R,CYR61,GATA2,NEK2,SUCO,MDFIC,MYDGF,WNT3A,NUP85,ELK3,RGMB,SALL4,STAT4,PYM1,MYBL2,ELK1,TP53INP2,NFIB,MAPKAPK2,ONECUT1,NCOA3,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,SORBS1,ARMCX3,UPF3B,GRHL2,IL15,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,PDGFA,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CHP1,CTH,SIRT1,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,IRS2,RBL1,KLF5,NRG1,IRF7,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,PARM1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,CST3,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,SYK,TRIM62,NCOA2,NFE2L3,PDGFC,HES1,RHOA,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,EIF5A2,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,ARRB1,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 2.055e-02 | -3.89 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | 181 | 27 | 17758 | 1761 |
GGA1,CXorf57,CR2,TGFBR1,TRMT2B,DDR1,LHFPL2,ADRBK2,PARM1,SLC9A7,HDAC9,GALNT3,WEE1,TNS3,BANK1,SLC4A4,UTP14C,FRAS1,PHLPP2,PLCG2,PHTF1,DRAM1,DTX4,TSPAN13,SYK,GM2A,SOCS5 |
| 2.055e-02 | -3.89 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 181 | 27 | 17758 | 1761 |
RIPK2,TACC1,NR4A1,COQ10B,SAT1,UTRN,PTGER4,FTH1,ZFAND5,TP53INP2,FOS,DNAJB9,SLC9A7,CD83,RAVER2,SOCS3,OTUD1,SLC16A6,KBTBD2,PLK2,FOSB,N4BP3,NR4A3,SGK1,ZMIZ1,TIPARP,JARID2 |
| 2.059e-02 | -3.88 | establishment of vesicle localization | biological process | GO:0051650 | 225 | 33 | 16441 | 1675 |
GRN,CTSZ,SYTL4,SYTL2,KIF5B,AP1M2,CTSC,DPYSL2,LMAN1,RAB27B,PACSIN1,SYTL3,PPP6R1,RASGRP1,MYO5A,SEC23A,RAB3B,KIF13A,COL7A1,SCRIB,MCFD2,BBS2,STX3,TRIM9,AP1AR,SERPINA1,SYT7,WIPI1,FGFR2,SYT13,NDE1,SHROOM2,SNPH |
| 2.061e-02 | -3.88 | V$E2F_Q6_01 | MSigDB lists | V$E2F_Q6_01 | 231 | 33 | 17758 | 1761 |
ARHGAP11A,IER5L,SORBS1,REPS2,PPM1J,NRP2,WEE1,E2F7,ZNF687,CYR61,DPYSL2,BMP7,RANBP1,PLK4,CITED2,TIAM1,ETV4,SYPL1,DDB2,ADAMTS2,PKMYT1,ERBB2IP,PRIM1,GPRC5B,RBL1,HOXA9,ZNF367,DCK,AGFG2,SFMBT1,KLF5,E2F8,MELK |
| 2.061e-02 | -3.88 | V$GATA1_04 | MSigDB lists | V$GATA1_04 | 231 | 33 | 17758 | 1761 |
ENO2,HOXB7,CHCHD7,CAST,TSC22D3,NDRG2,TNFRSF19,PPP2R3A,ZNF385B,NRP2,MECOM,FOXP2,RALGPS2,ANKS1B,ARHGEF37,CALD1,MITF,TWIST1,HES1,TACC1,FZD4,NR3C1,AIF1L,PITX2,PLEKHG6,MAMDC4,KLF12,SEMA4D,FAM117A,RHOBTB2,ARPC2,CAPN1,PKIA |
| 2.062e-02 | -3.88 | kidney epithelium development | biological process | GO:0072073 | 129 | 21 | 16441 | 1675 |
HES1,LGR4,FMN1,IQGAP1,RET,EPHA4,SOX9,SDC4,SDC1,EPCAM,CTNNBIP1,FAT4,FGFR2,NPNT,BMP7,DLG1,TACSTD2,GDF11,SOX8,OSR1,ADAMTS16 |
| 2.063e-02 | -3.88 | KEGG_GNRH_SIGNALING_PATHWAY | MSigDB lists | KEGG_GNRH_SIGNALING_PATHWAY | 101 | 17 | 17758 | 1761 |
MAP3K3,PLA2G4A,CALM1,CALM3,ITPR2,ELK1,ITPR3,PRKACA,GNA11,CALM2,GNAS,ITPR1,MAPK11,CACNA1D,PLD1,PLCB2,MAPK12 |
| 2.064e-02 | -3.88 | DAZARD_UV_RESPONSE_CLUSTER_G2 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G2 | 29 | 7 | 17758 | 1761 |
SGK1,CLDN4,TACSTD2,CTGF,CITED2,TOB1,IER3 |
| 2.064e-02 | -3.88 | REACTOME_CA_DEPENDENT_EVENTS | MSigDB lists | REACTOME_CA_DEPENDENT_EVENTS | 29 | 7 | 17758 | 1761 |
PLA2G4A,CALM2,CALM3,PRKAR2B,ADRBK1,PRKACA,CALM1 |
| 2.064e-02 | -3.88 | RAS_GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | RAS_GTPASE_ACTIVATOR_ACTIVITY | 29 | 7 | 17758 | 1761 |
ARHGEF10L,DOCK4,ARAP3,RAPGEF2,RALBP1,RASA2,RASA1 |
| 2.064e-02 | -3.88 | LY_AGING_PREMATURE_DN | MSigDB lists | LY_AGING_PREMATURE_DN | 29 | 7 | 17758 | 1761 |
CENPA,PKMYT1,CCNF,FOXM1,BARD1,RANBP1,MYBL2 |
| 2.064e-02 | -3.88 | GNF2_ATM | MSigDB lists | GNF2_ATM | 29 | 7 | 17758 | 1761 |
BTN3A2,BTN3A1,HECA,DENND2D,RASGRP1,DEF6,RASGRP2 |
| 2.064e-02 | -3.88 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | MSigDB lists | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | 29 | 7 | 17758 | 1761 |
CASP3,BMF,BCL2L1,AKT1,CASP9,TP53,BAX |
| 2.064e-02 | -3.88 | IWANAGA_E2F1_TARGETS_INDUCED_BY_SERUM | MSigDB lists | IWANAGA_E2F1_TARGETS_INDUCED_BY_SERUM | 29 | 7 | 17758 | 1761 |
PGM2L1,FAM111A,PCGF5,GGH,FIGNL1,PSIP1,PLK4 |
| 2.064e-02 | -3.88 | YANAGIHARA_ESX1_TARGETS | MSigDB lists | YANAGIHARA_ESX1_TARGETS | 29 | 7 | 17758 | 1761 |
PRKAA2,GNS,SS18,IL18,IL6ST,CRTAP,INPP4B |
| 2.066e-02 | -3.88 | ISLR (immunoglobulin superfamily containing leucine-rich repeat) | protein interactions | 3671 | 52 | 11 | 16036 | 1726 |
CHSY3,CD109,SLC25A4,BMP7,GALNS,PCYOX1,ARSK,CNPY3,MGAT5,GCNT1,SGPL1 |
| 2.068e-02 | -3.88 | proteinaceous extracellular matrix | cellular component | GO:0005578 | 357 | 48 | 17570 | 1756 |
COL9A3,LTBP1,CTHRC1,LGALS3,HSPG2,HAPLN3,ITGA6,P3H2,COL18A1,COL4A5,SLC1A3,ADAMTSL4,FBLN1,LGALS3BP,NOV,MUC4,CTGF,CYR61,NPNT,FRAS1,FLRT3,CST3,COL6A1,DLG1,NTN4,WNT3A,CRTAP,ADAMTS2,TIMP2,COL6A2,FBLN5,VWA1,COL7A1,LOXL2,ERBB2IP,DAG1,CRISPLD2,COL12A1,GPLD1,TIMP3,SERPINA1,MMP17,MATN2,BMP1,ADAMTS14,LTBP2,COL16A1,ADAMTS16 |
| 2.076e-02 | -3.87 | V$PAX4_04 | MSigDB lists | V$PAX4_04 | 206 | 30 | 17758 | 1761 |
ZNF462,CCNI,HOXB7,CHCHD7,VANGL1,MORF4L2,DUSP4,ITPR3,ELK1,NFIB,SIX4,WWP2,NFIX,PITX2,FOXP2,ITGA3,IGF1R,ANKS1B,RGS3,CALD1,HOXA9,LMO4,RAP2C,BCL6,FAM63A,KLF9,C1orf43,MYT1,KLF7,JARID2 |
| 2.076e-02 | -3.87 | regulation of endopeptidase activity | biological process | GO:0052548 | 376 | 51 | 16441 | 1675 |
CASP3,NKX3-1,SERPINE2,RPS6KA1,DAP,CAST,PSME2,PTTG1,RET,PSME1,BCAP31,CD109,TFAP4,APLP2,CARD8,CTGF,CYR61,CTSC,CST3,DAPK1,BAX,CDKN1B,SORL1,EGLN3,WNT3A,CDKN2D,F2R,SIRT1,TIMP2,RHOA,AKT1,ACVR1C,PLAUR,CASP9,FURIN,COL7A1,SLC11A2,POR,FAS,TIMP3,SERPINA1,NGFRAP1,SPINT2,ARRB1,SERPINB6,SERPINI1,GPER1,MAP3K5,SERPINB1,IFI6,XDH |
| 2.078e-02 | -3.87 | negative regulation of MAP kinase activity | biological process | GO:0043407 | 69 | 13 | 16441 | 1675 |
SPRED1,PTPRJ,BMP7,RGS3,STK38,DUSP10,SORL1,DAB2IP,RGS14,DUSP4,GSTP1,HIPK3,SPRY2 |
| 2.084e-02 | -3.87 | MODULE_197 | MSigDB lists | MODULE_197 | 173 | 26 | 17758 | 1761 |
PLK1,SMARCA2,CDKN1C,FOXM1,PTTG1,SOX9,ETV5,NDC80,MYBL2,PTGER4,KIF23,CCNB1,FOS,CDK1,WEE1,HSF2,ETS2,TFAP2A,GTF2F2,TLE1,KLF11,BUB1,CITED2,CCNB2,MYT1,UBE2C |
| 2.093e-02 | -3.87 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1423 | 168 | 16441 | 1675 |
LGR4,EPAS1,HEXB,RET,MORF4L2,CAMK1D,PDGFB,EPCAM,HSF2,GRHL1,NPNT,IL31RA,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,AHRR,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,GATA2,MDFIC,MYDGF,WNT3A,NUP85,ELK3,RGMB,SALL4,STAT4,MYBL2,ELK1,TP53INP2,NFIB,NCOA3,ONECUT1,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,GRHL2,ARMCX3,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CTH,SIRT1,AKT1,RIPK2,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,NRG1,IRF7,KLF5,GLIS3,ANXA3,NKX3-1,PINK1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,TRIM62,NCOA2,NFE2L3,HES1,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,ARRB1,HMGA1,GPER1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 2.093e-02 | -3.87 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1423 | 168 | 16441 | 1675 |
LGR4,EPAS1,HEXB,RET,MORF4L2,CAMK1D,PDGFB,EPCAM,HSF2,GRHL1,NPNT,IL31RA,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,AHRR,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,GATA2,MDFIC,MYDGF,WNT3A,NUP85,ELK3,RGMB,SALL4,STAT4,MYBL2,ELK1,TP53INP2,NFIB,NCOA3,ONECUT1,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,GRHL2,ARMCX3,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CTH,SIRT1,AKT1,RIPK2,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,NRG1,IRF7,KLF5,GLIS3,ANXA3,NKX3-1,PINK1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,TRIM62,NCOA2,NFE2L3,HES1,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,NR1D2,ACVRL1,NR4A3,ARRB1,HMGA1,GPER1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 2.093e-02 | -3.87 | regulation of lipid catabolic process | biological process | GO:0050994 | 48 | 10 | 16441 | 1675 |
IRS2,ADORA1,AKT1,THRA,PPARA,TWIST1,IDH1,TYSND1,PLIN5,GPLD1 |
| 2.093e-02 | -3.87 | actin filament bundle assembly | biological process | GO:0051017 | 48 | 10 | 16441 | 1675 |
SORBS1,RHOA,SWAP70,ADD1,EPS8,ARRB1,EZR,ESPN,SHROOM2,DPYSL3 |
| 2.093e-02 | -3.87 | CASP3 (caspase 3) | protein interactions | 836 | 175 | 28 | 16036 | 1726 |
PLA2G4A,CASP3,KCNIP3,ADD1,AKT1,CAST,PTTG1,CASP9,PLEKHO1,PDE5A,IL18,ARHGDIB,PRKCQ,PKN1,BCAR1,BCAP31,PSIP1,CASP4,RASA1,NEO1,WEE1,CDH1,TFAP2A,BAX,CTTN,HSPB1,SOCS5,ATG4D |
| 2.096e-02 | -3.87 | transcriptional repressor activity, RNA polymerase II transcription factor binding | molecular function | GO:0001191 | 84 | 15 | 16491 | 1673 |
AHRR,JADE1,PITX2,SMARCA2,CITED4,BHLHE41,TBX18,PPARA,NFE2L1,TLE1,HDAC1,CITED2,NFIB,PSIP1,WWP2 |
| 2.101e-02 | -3.86 | Galactosemia | SMPDB pathways | SMP00182 | 13 | 5 | 978 | 131 |
AKR1B1,PGM1,GAA,GLA,UGP2 |
| 2.101e-02 | -3.86 | Galactose Metabolism | SMPDB pathways | SMP00043 | 13 | 5 | 978 | 131 |
AKR1B1,PGM1,GAA,GLA,UGP2 |
| 2.106e-02 | -3.86 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | 109 | 18 | 17758 | 1761 |
LASP1,BCAM,UGP2,PEX6,S100A11,CD63,MPP1,YES1,BCL2L1,ADAMTSL4,CMTM6,SH3BP1,GDE1,PIM1,MINPP1,NAGA,CAPN1,SNPH |
| 2.107e-02 | -3.86 | regulation of organelle organization | biological process | GO:0033043 | 1022 | 124 | 16441 | 1675 |
GAS2L1,MTM1,NF2,SSH1,ADD1,DLGAP5,PTTG1,ARFGEF1,TP53,F11R,BCL2L1,CCNB1,HDAC6,PDGFB,SDC1,APC2,MNS1,SPTB,IER3,PDGFA,RPS6KA2,CTGF,SIVA1,BCL6,DLG1,PLK4,VAT1,CDKN1B,ESPN,TWIST1,TACSTD2,DIXDC1,CTTN,LMAN1,NEB,PLK1,PPIF,SIRT1,CAMSAP3,SSH3,AKT1,CAPN6,CDC20,PTGER4,NBPF3,EZR,PRKCQ,NUSAP1,PIF1,PKMYT1,CCNF,ANLN,SLC25A5,TRIM9,MID1IP1,ARHGEF19,DNM1L,PLK2,LIMK1,TRIOBP,EFNA5,SPTBN5,NRG1,TMOD2,ARF6,F2RL1,PINK1,BMF,TBC1D1,CKAP2,CIT,EPS8,SDC4,PSMD10,NCKAP1,LMNA,IGF1R,PTEN,GATA2,BMP7,FAM20B,TBCD,NEK2,BAX,BUB1,PIKFYVE,CNOT6L,WNT3A,CCDC88A,MYO5A,HES1,RHOA,FMN1,PLAUR,PIK3R1,PIP4K2C,RGCC,STMN3,EPHA1,NUBP1,BORA,KIF11,CDK5R1,RASA1,AP1AR,SWAP70,PLEKHH2,FGFR2,CTSV,CDCA5,AURKA,ARRB1,GPER1,CENPE,HMGA1,ARPC2,FZD5,SHROOM2,TBC1D4,UBE2C,ESPL1,AFAP1,JARID2,ADAMTS16 |
| 2.107e-02 | -3.86 | PX | pfam domains | PF00787 | 48 | 10 | 16629 | 1696 |
SNX18,SGK3,SNX16,PIK3C2B,PLD1,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 2.109e-02 | -3.86 | Trans-sulfuration pathway | WikiPathways | WP2333 | 10 | 4 | 4455 | 516 |
GCLM,GOT1,AHCY,CTH |
| 2.109e-02 | -3.86 | liver-other-adenoma | COSMIC cancer mutations | liver-other-adenoma | 17 | 5 | 17775 | 1757 |
GNAS,JAK1,IL6ST,PIK3CA,TP53 |
| 2.111e-02 | -3.86 | ARRDC1 (arrestin domain containing 1) | protein interactions | 92714 | 33 | 8 | 16036 | 1726 |
PBK,ITCH,OSBPL3,ARRB1,WWP1,WDR45B,KCTD2,WWP2 |
| 2.111e-02 | -3.86 | IFI30 (interferon, gamma-inducible protein 30) | protein interactions | 10437 | 33 | 8 | 16036 | 1726 |
TIMP3,LLGL2,DAPK1,PDIA5,EGFL7,FBLN1,SNX12,TRIM68 |
| 2.111e-02 | -3.86 | BNIP3L (BCL2/adenovirus E1B 19kDa interacting protein 3-like) | protein interactions | 665 | 33 | 8 | 16036 | 1726 |
GNB5,TP53,CAMK1D,BCL2L1,SMCO4,RHEB,ATP13A2,GABARAPL1 |
| 2.111e-02 | -3.86 | GLOD4 (glyoxalase domain containing 4) | protein interactions | 51031 | 33 | 8 | 16036 | 1726 |
DAZAP1,TXN,NR4A1,GLO1,GOT1,NANS,BCL2L1,HSPB1 |
| 2.111e-02 | -3.86 | Rap1 signalling | REACTOME pathways | R-HSA-392517 | 16 | 5 | 8202 | 867 |
RAP1GAP,PRKACA,RASGRP1,PRKG1,RASGRP2 |
| 2.113e-02 | -3.86 | positive regulation of endothelial cell migration | biological process | GO:0010595 | 62 | 12 | 16441 | 1675 |
ANXA3,PLCG1,AKT1,PLPP3,PDGFB,ETS1,HSPB1,BCAR1,SRPX2,NRP2,HDAC9,GPLD1 |
| 2.116e-02 | -3.86 | GTATTAT,MIR-369-3P | MSigDB lists | GTATTAT,MIR-369-3P | 198 | 29 | 17758 | 1761 |
SIRT1,CCNE2,SUN2,LTBP1,SPRED1,HES1,MMD,KIF20A,ZNF395,NUAK1,AMFR,OXR1,ETV5,ZFAND5,EPS8L2,NCOA3,MAP2,CDK19,RAB11FIP2,FLRT3,MGAT4A,LIMK1,PCDH19,MAL2,PDE4D,SLC39A10,PIKFYVE,CEP41,PKIA |
| 2.116e-02 | -3.86 | KEGG_FOCAL_ADHESION | MSigDB lists | KEGG_FOCAL_ADHESION | 198 | 29 | 17758 | 1761 |
MYL9,RASGRF1,PDGFC,COL6A2,RHOA,AKT1,ITGA6,PIK3R1,ERBB2,ELK1,BCAR1,PDGFB,MYL12A,ARHGAP35,PGF,PDGFA,CCND1,ITGA3,IGF1R,ITGB8,PTEN,SHC3,ITGA7,COL6A1,PIK3CA,PIK3CD,ITGAV,TLN2,MYL12B |
| 2.117e-02 | -3.86 | IGFBP_N_1 | prosite domains | PS00222 | 11 | 4 | 11866 | 1235 |
NOV,IGFBP2,CTGF,CYR61 |
| 2.117e-02 | -3.86 | THIOL_PROTEASE_HIS | prosite domains | PS00639 | 11 | 4 | 11866 | 1235 |
CTSL,TINAGL1,CTSC,CTSV |
| 2.120e-02 | -3.85 | - | gene3d domains | 2.60.120.290 | 52 | 11 | 9988 | 1080 |
PDGFC,PCOLCE,ST14,MEGF8,BMP1,NETO2,ATRNL1,KREMEN1,DCBLD1,NRP2,TLL2 |
| 2.121e-02 | -3.85 | Bub1b (budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)) | protein interactions | 12236 | 27 | 7 | 16036 | 1726 |
ASAH1,BUB1,NUF2,ZWINT,SPC25,CDC20,NDC80 |
| 2.121e-02 | -3.85 | MAP2K6 (mitogen-activated protein kinase kinase 6) | protein interactions | 5608 | 27 | 7 | 16036 | 1726 |
MAPKAPK2,MAP3K5,PKN1,PTEN,PLCB2,STAT4,MAPK12 |
| 2.121e-02 | -3.85 | FAHD1 (fumarylacetoacetate hydrolase domain containing 1) | protein interactions | 81889 | 27 | 7 | 16036 | 1726 |
CAB39,DHTKD1,GOT1,DAZAP1,NANS,GUSB,CPT2 |
| 2.121e-02 | -3.85 | PBK (PDZ binding kinase) | protein interactions | 55872 | 27 | 7 | 16036 | 1726 |
ARRDC1,MSL1,CCNB1,CDK1,DOK4,DLG1,TP53 |
| 2.121e-02 | -3.85 | FRS2 (fibroblast growth factor receptor substrate 2) | protein interactions | 10818 | 27 | 7 | 16036 | 1726 |
PTPRF,SORBS1,DDR1,FGFR2,SPRY2,GAB1,RET |
| 2.126e-02 | -3.85 | KEGG_APOPTOSIS | MSigDB lists | KEGG_APOPTOSIS | 86 | 15 | 17758 | 1761 |
ENDOD1,CASP3,AKT1,NFKBIA,PIK3R1,CASP9,TP53,BAX,PIK3CA,PRKAR2B,PIK3CD,BCL2L1,PRKACA,CAPN1,FAS |
| 2.126e-02 | -3.85 | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | 86 | 15 | 17758 | 1761 |
GRN,CD99,ATP6V0B,TXN,S100A4,DBI,SAT1,SPINT2,NDUFA4,FTH1,MANF,COX6C,RNPEP,ACOT7,GPX4 |
| 2.126e-02 | -3.85 | apoptotic signaling pathway | biological process | GO:0097190 | 368 | 50 | 16441 | 1675 |
LAMP1,ZMAT1,CASP3,ARHGEF3,BMF,SORT1,ARHGEF11,DAP,TP53,BCL2L1,ZNF385B,ARHGEF16,SGPL1,IER3,ADORA1,SIVA1,BAX,DAPK1,TMBIM6,DAB2IP,SELK,CD70,TNFRSF12A,ERBB3,SCN2A,TIAM1,CYP1B1,SIRT1,PRODH,AKT1,CASP9,ERO1A,PIK3R1,CD40,CASP4,ABR,FAS,DNAJC10,NGFRAP1,DNM1L,ITPR1,UACA,ITGAV,MAP3K5,UNC5B,IFI6,ARHGEF9,MELK,ARHGEF4,FGD1 |
| 2.130e-02 | -3.85 | Glycosphingolipid metabolism | REACTOME pathways | R-HSA-1660662 | 40 | 9 | 8202 | 867 |
ARSG,HEXB,ASAH1,CTSA,GLA,ARSB,ARSK,CPTP,GM2A |
| 2.132e-02 | -3.85 | CTAWWWATA_V$RSRFC4_Q2 | MSigDB lists | CTAWWWATA_V$RSRFC4_Q2 | 343 | 46 | 17758 | 1761 |
SLC2A4,CPEB4,HOXB7,SOX9,LMCD1,NDRG2,TRIB2,SPTB,SYTL2,HDAC9,SCML1,ELMO2,REEP1,SLC44A1,OPN3,NEK2,TWIST1,TSPAN13,PHKA2,NPTXR,ARMCX6,RIMS2,CRTAP,CYP26B1,RASGRF1,HES1,SMARCA2,TRIM8,TIMP2,PLEKHA6,NR4A1,S100A4,PANK1,PRX,RASGRP2,DPYSL3,PITX2,SLC25A4,COL13A1,WIPI1,ITGA7,RAP2C,SIPA1L1,FAM117A,GRIN2D,HSPB1 |
| 2.135e-02 | -3.85 | cellular homeostasis | biological process | GO:0019725 | 673 | 85 | 16441 | 1675 |
GAA,MTM1,CCDC109B,TXN,ADD1,TMX4,ATP2C2,HEXB,PDIA5,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,APLP2,ATP6V0B,PLCG2,PIK3CA,TRPC1,RAB20,TMEM64,SLC39A10,MYT1,PDIA6,F2R,CHP1,SIRT1,CLCN3,CD55,ACO1,SLC11A2,ATP1B1,RAB38,CD40,ITPR3,PRIM1,ATP13A2,EDNRA,IRS2,DNAJC10,ENPP1,ATP1A1,IDE,WFS1,ATP7B,INPP4B,F2RL1,AIFM3,CALB2,MTL5,SLC25A27,ABCG2,PDIA3,PDIA4,CA2,GATA2,KCNN4,BAX,SGK3,SGK1,TMBIM6,SLC12A2,ATP2B1,GCLC,ERO1A,ANO6,PIK3R1,GRIN1,GYLTL1B,TTC7A,PDK3,TXNDC11,NUBP1,PRDX4,SWAP70,SLC4A4,RAB11FIP2,ITPR1,SLC4A3,MCUR1,ATP1B3,GPER1,NDFIP1,JAK3,CYBRD1 |
| 2.136e-02 | -3.85 | spindle organization | biological process | GO:0007051 | 114 | 19 | 16441 | 1675 |
SUN2,RHOA,SPC25,ASPM,NDC80,MYBL2,KIF23,EZR,STIL,KIF11,DCTN6,PLK2,DLG1,NEK2,TUBG1,AURKA,RGS14,WDR62,ESPL1 |
| 2.137e-02 | -3.85 | NAD/diacylglycerol_kinase | interpro domains | IPR016064 | 17 | 5 | 18293 | 1814 |
NADK2,DGKH,DGKG,DGKQ,DGKE |
| 2.137e-02 | -3.85 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3 | 17 | 5 | 17758 | 1761 |
PKP2,LMO7,CPEB4,F2RL1,MYL12A |
| 2.137e-02 | -3.85 | BIOCARTA_CCR5_PATHWAY | MSigDB lists | BIOCARTA_CCR5_PATHWAY | 17 | 5 | 17758 | 1761 |
CALM2,CALM3,PLCG1,FOS,CALM1 |
| 2.137e-02 | -3.85 | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | MSigDB lists | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | 17 | 5 | 17758 | 1761 |
MX1,IRF7,IFIT1,IFIT3,IFI6 |
| 2.137e-02 | -3.85 | BIOCARTA_IL7_PATHWAY | MSigDB lists | BIOCARTA_IL7_PATHWAY | 17 | 5 | 17758 | 1761 |
JAK1,JAK3,NMI,PIK3R1,PIK3CA |
| 2.137e-02 | -3.85 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | MSigDB lists | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | 17 | 5 | 17758 | 1761 |
CAB39,PRKAA2,STRADB,PRKAG2,RHEB |
| 2.137e-02 | -3.85 | chr6p23 | MSigDB lists | chr6p23 | 17 | 5 | 17758 | 1761 |
RNF182,KIF13A,MYLIP,RANBP9,CD83 |
| 2.137e-02 | -3.85 | LOPEZ_EPITHELIOID_MESOTHELIOMA | MSigDB lists | LOPEZ_EPITHELIOID_MESOTHELIOMA | 17 | 5 | 17758 | 1761 |
PTPRF,BTG3,LRRC1,ANXA9,COBL |
| 2.137e-02 | -3.85 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN | 17 | 5 | 17758 | 1761 |
GAA,NFKBIZ,C10orf54,IL6ST,CBX7 |
| 2.137e-02 | -3.85 | TRAYNOR_RETT_SYNDROM_DN | MSigDB lists | TRAYNOR_RETT_SYNDROM_DN | 17 | 5 | 17758 | 1761 |
PTPRF,KLF5,ENPP1,P4HA2,ITGA6 |
| 2.137e-02 | -3.85 | NEGATIVE_REGULATION_OF_CELL_ADHESION | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_ADHESION | 17 | 5 | 17758 | 1761 |
ARHGDIB,NF2,PTEN,ACVRL1,RASA1 |
| 2.137e-02 | -3.85 | BIOCARTA_ERK5_PATHWAY | MSigDB lists | BIOCARTA_ERK5_PATHWAY | 17 | 5 | 17758 | 1761 |
PLCG1,AKT1,RPS6KA1,PIK3R1,PIK3CA |
| 2.137e-02 | -3.85 | MODULE_537 | MSigDB lists | MODULE_537 | 17 | 5 | 17758 | 1761 |
NRG2,BCL2L1,SEMA4D,MYBL2,IER3 |
| 2.137e-02 | -3.85 | SA_TRKA_RECEPTOR | MSigDB lists | SA_TRKA_RECEPTOR | 17 | 5 | 17758 | 1761 |
PIK3CD,RHOA,AKT1,ELK1,PIK3CA |
| 2.139e-02 | -3.85 | skin-face-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-face-other-atypical_Spitzoid_tumour | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.139e-02 | -3.85 | central_nervous_system-brain-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma | 23 | 6 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 2.139e-02 | -3.85 | skin-upper_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_leg-other-atypical_Spitzoid_tumour | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.139e-02 | -3.85 | skin-scalp-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-scalp-benign_melanocytic_nevus-Spitz | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.139e-02 | -3.85 | skin-arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-arm-other-atypical_Spitzoid_tumour | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.139e-02 | -3.85 | skin-lower_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-lower_leg-other-atypical_Spitzoid_tumour | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.139e-02 | -3.85 | atypical_Spitzoid_tumour | COSMIC cancer mutations | atypical_Spitzoid_tumour | 23 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.142e-02 | -3.84 | cell projection assembly | biological process | GO:0030031 | 267 | 38 | 16441 | 1675 |
TTC8,WASF3,TCTN2,AK7,POC1B,ITGA6,RAB23,NCKAP1,EMP2,PDGFA,LRRC6,FXYD5,CTTN,SNX10,NUP85,CCDC88A,DNAAF3,SPEF2,CELSR2,CFAP46,RAPGEF2,ANO6,SPATA13,EZR,BBS2,ARHGEF26,DZIP1L,CEP162,ONECUT1,STK26,RAP2C,TRAF3IP1,FGD6,KLF5,CEP41,ARHGEF4,EHD1,FGD1 |
| 2.150e-02 | -3.84 | acetylgalactosaminyltransferase activity | molecular function | GO:0008376 | 35 | 8 | 16491 | 1673 |
CHSY3,GALNT3,B3GALNT1,GALNT12,C1GALT1C1,GALNT7,B4GALNT1,CHPF |
| 2.153e-02 | -3.84 | Viral myocarditis | KEGG pathways | hsa05416 | 58 | 12 | 6908 | 758 |
CCND1,HLA-B,CASP3,CD55,HLA-F,HLA-E,CASP9,HLA-C,CD40,SGCB,DAG1,HLA-A |
| 2.153e-02 | -3.84 | Integrin cell surface interactions | REACTOME pathways | R-HSA-216083 | 67 | 13 | 8202 | 867 |
COL9A3,ITGA3,ITGB8,CDH1,HSPG2,COL13A1,ITGA7,ITGA6,COL18A1,F11R,ITGAV,COL16A1,DAG1 |
| 2.155e-02 | -3.84 | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | 190 | 28 | 17758 | 1761 |
TPRN,SEC61B,GUSB,SLC25A13,TESK2,MRAS,ARHGDIB,FAM198B,NUCB2,FAM81A,CDK1,CYP4F3,LTBP3,KIAA1161,H1FX,DHX32,CDKN2C,FAM111A,ENPP1,IL6ST,BDH1,OPN3,NR4A3,ABCD1,TSPAN13,TECR,PPP2R2D,GPX4 |
| 2.155e-02 | -3.84 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | 190 | 28 | 17758 | 1761 |
PPIF,SHMT1,TNIP1,ENO2,CD63,GCLC,PTGER4,NFE2L1,MORF4L2,NANS,CD40,TP53INP2,RNF19B,LMNA,GLCE,CD83,PRIM1,GABARAPL1,IDE,PLK2,ZFP36,SIVA1,SLC44A1,SELK,SERPINB1,NUP85,ACOT7,ABCC1 |
| 2.155e-02 | -3.84 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | 190 | 28 | 17758 | 1761 |
SUN2,MRPS33,CCDC109B,RHOA,NFKBIE,PQLC3,NR3C1,CKAP2,ATP8A1,SEPT6,ITGA6,PRKCQ,CNTNAP2,BLVRA,ATP1B1,NCKAP1,SH3KBP1,DGKE,EPCAM,PTPRF,AXL,PHTF1,HMGA1,RGS14,PLIN3,SYTL3,AHR,TMEM131 |
| 2.155e-02 | -3.84 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 190 | 28 | 17758 | 1761 |
EXPH5,CCNI,PHF20L1,MCTP1,UGP2,PAPSS2,RC3H2,EPS8,FBXO9,ITPR2,RAD17,SAV1,DPP8,SEPP1,RHEB,DHX32,MFAP3L,RPL12,PSMD1,RAB11FIP2,DNM1L,PTER,FAM114A1,DHTKD1,MDH1,ARPC2,KLF7,GCNT1 |
| 2.155e-02 | -3.84 | GSE17721_0.5H_VS_4H_LPS_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDM_DN | 190 | 28 | 17758 | 1761 |
GCA,PMPCB,LZTFL1,RUNX2,GRHL2,MOSPD2,KLHL13,FRMD6,SLC39A8,MPP1,IQGAP1,IL18,SPTLC2,RBM47,ETS2,ARTN,FAAH,LMO4,LHX6,SLC44A1,UBE2J1,PRKCDBP,CD70,PIKFYVE,PTPRE,TRAF5,MGAT5,HOXC13 |
| 2.155e-02 | -3.84 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | 190 | 28 | 17758 | 1761 |
PPIF,NKX3-1,PSMB4,TNIP1,IL15RA,RIPK2,NR3C1,ZC3H11A,HLA-E,STAT4,DUSP4,C15orf39,DDR1,IER3,ETS2,KBTBD2,NFKBIA,SLC2A6,RAP2C,IRF7,NDE1,ST3GAL1,RASGRP1,SMAGP,ATP2B1,JARID2,EHD1,LAMP3 |
| 2.155e-02 | -3.84 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 190 | 28 | 17758 | 1761 |
TIMP2,PODXL2,RAPGEF2,HEXB,PDIA3,NENF,MORF4L2,CRABP2,ARHGEF16,RHEB,LMNA,PDIA4,FUCA1,UAP1,WIPI1,GDE1,PRCP,FUT8,RRBP1,CD9,TMBIM6,SPCS3,TECR,CITED2,HSPB1,GM2A,FAH,MAPK12 |
| 2.157e-02 | -3.84 | CSR_EARLY_UP.V1_DN | MSigDB lists | CSR_EARLY_UP.V1_DN | 133 | 21 | 17758 | 1761 |
ERMAP,HSPG2,MOSPD2,PEX6,NBPF3,PDE5A,NPHP3,DHRS3,FAM46C,ADAMTSL4,SLC9A7,OTUD1,WEE1,GRHL1,TRIM69,TFAP2A,FAM63A,CDKN1B,ARL4D,ERAP2,SNPH |
| 2.158e-02 | -3.84 | adenoma-nodule-goitre | COSMIC cancer mutations | adenoma-nodule-goitre | 64 | 12 | 17775 | 1757 |
GNAS,CDH1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,JAK3,GNA11 |
| 2.159e-02 | -3.84 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 300 | 41 | 17758 | 1761 |
UGP2,ENO2,ZNF395,GNPDA1,TSC22D3,BLVRB,SDC4,NDRG2,FTH1,PJA2,KREMEN1,SIRPA,SGPL1,SNTA1,DTX3L,ADD3,ZFP36,CD9,CNNM4,RAB20,CITED2,SNX10,GM2A,CPD,SGCE,PRODH,PDGFC,PTPRU,SAT1,AK4,MDK,HLF,RPL12,AGPAT2,PLOD2,PTER,TMEM30A,NFKBIA,SYT13,ATP1B3,RNF146 |
| 2.160e-02 | -3.84 | human chr1p32 | chromosome location | human chr1p32 | 23 | 5 | 26250 | 1887 |
TESK2,CDKN2C,TACSTD2,STIL,CPT2 |
| 2.164e-02 | -3.83 | ATN1 (atrophin 1) | protein interactions | 1822 | 101 | 18 | 16036 | 1726 |
GRN,LTBP1,CASP3,MBP,FBLN5,PLSCR1,HSPG2,ITCH,AES,FBLN1,WWP2,ALG13,MEGF8,TLE1,WWP1,DVL2,MDFI,PCSK5 |
| 2.169e-02 | -3.83 | positive regulation of phospholipase activity | biological process | GO:0010518 | 84 | 15 | 16441 | 1675 |
CALM2,PLCG1,ADRBK1,CYR61,FGFR2,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,ARF4,EDNRA |
| 2.170e-02 | -3.83 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta) | protein interactions | 7529 | 341 | 49 | 16036 | 1726 |
LMO7,CDK17,SORBS1,TBC1D1,FRMD6,CAMKK1,RPS6KA1,DCAF7,TESK2,PKP2,KIF23,NCKAP1,KIF5B,WEE1,SIPA1L2,IGF1R,RALGPS2,CDK16,RGS3,FRYL,ZFP36,KIF13B,OSBPL3,DAPK1,BAX,CDKN1B,DOCK4,MAP3K3,RASGRF1,HES1,ING1,TESK1,KIF1C,OPTN,IRS2,RAB11FIP2,SHROOM3,STK38,RAB11FIP1,PPM1H,ARRB1,CDK18,GEM,WDR62,TANC2,REEP4,TBC1D4,HSPB1,USP43 |
| 2.170e-02 | -3.83 | Frizzled_dom | interpro domains | IPR020067 | 23 | 6 | 18293 | 1814 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6 |
| 2.170e-02 | -3.83 | Actinin_actin-bd_CS | interpro domains | IPR001589 | 23 | 6 | 18293 | 1814 |
CLMN,SPTBN5,SPTB,SYNE2,UTRN,PLS3 |
| 2.170e-02 | -3.83 | HANSON_HRAS_SIGNALING_VIA_NFKB | MSigDB lists | HANSON_HRAS_SIGNALING_VIA_NFKB | 23 | 6 | 17758 | 1761 |
COL18A1,TMOD2,RNF19B,CGREF1,KLF3,ALDH1A3 |
| 2.170e-02 | -3.83 | WANG_LSD1_TARGETS_UP | MSigDB lists | WANG_LSD1_TARGETS_UP | 23 | 6 | 17758 | 1761 |
MDK,EZR,PDGFA,IGFBP2,ELK3,CDKN1C |
| 2.170e-02 | -3.83 | KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION | MSigDB lists | KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION | 23 | 6 | 17758 | 1761 |
MDH1,ATP1A1,ATP1B3,ATP1B1,CA2,SLC4A4 |
| 2.170e-02 | -3.83 | BIOCARTA_RAC1_PATHWAY | MSigDB lists | BIOCARTA_RAC1_PATHWAY | 23 | 6 | 17758 | 1761 |
PLD1,LIMK1,RALBP1,CDK5R1,PIK3R1,PIK3CA |
| 2.170e-02 | -3.83 | chr5q21 | MSigDB lists | chr5q21 | 23 | 6 | 17758 | 1761 |
EFNA5,EPB41L4A,CPEB4,GNPDA1,RGMB,C5orf30 |
| 2.170e-02 | -3.83 | BIOCARTA_IGF1R_PATHWAY | MSigDB lists | BIOCARTA_IGF1R_PATHWAY | 23 | 6 | 17758 | 1761 |
PRKAR2B,IGF1R,AKT1,RPS6KA1,PIK3R1,PIK3CA |
| 2.170e-02 | -3.83 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | MSigDB lists | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | 23 | 6 | 17758 | 1761 |
NCOA3,RUNX2,CTGF,NCOA2,TEAD3,PPARA |
| 2.170e-02 | -3.83 | BIOCARTA_CTCF_PATHWAY | MSigDB lists | BIOCARTA_CTCF_PATHWAY | 23 | 6 | 17758 | 1761 |
CDKN1B,TGFBR1,PTEN,PIK3R1,PIK3CA,TP53 |
| 2.170e-02 | -3.83 | COLLAGEN | MSigDB lists | COLLAGEN | 23 | 6 | 17758 | 1761 |
COL18A1,COL9A3,COL4A5,COL7A1,COL13A1,COL16A1 |
| 2.172e-02 | -3.83 | ETS_DOMAIN_1 | prosite domains | PS00345 | 22 | 6 | 11866 | 1235 |
ELK3,ETS2,ELK1,ETS1,ETV4,ETV5 |
| 2.172e-02 | -3.83 | HIF-2-alpha transcription factor network | Pathway Interaction DB | hif2pathway | 34 | 10 | 2227 | 331 |
SIRT1,EPAS1,ABCG2,TWIST1,SLC11A2,CITED2,ELK1,EGLN3,ETS1,EGLN1 |
| 2.190e-02 | -3.82 | ZHANG_TLX_TARGETS_60HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_60HR_DN | 266 | 37 | 17758 | 1761 |
HJURP,NUF2,CENPN,HMGXB4,FANCI,TOP2A,FAM111A,WEE1,DACT1,PLK4,BUB1,SLC12A2,TIPARP,NUP85,LAMP3,PLK1,HMMR,SHMT1,FIGNL1,PBK,MYBL2,AK4,ANLN,KIF11,FRMD4B,PRIM1,SLC4A4,FAM64A,RBL1,DCK,CDCA5,CDCA7L,ETAA1,NCAPG2,CCNB2,E2F8,MELK |
| 2.192e-02 | -3.82 | V$MYB_Q5_01 | MSigDB lists | V$MYB_Q5_01 | 249 | 35 | 17758 | 1761 |
LTBP1,PPP4R4,HEBP1,PRKACA,SIX4,PRRG4,SLC9A7,FOXP2,MDM1,SLC16A6,DACT1,FRAS1,LHX6,TOX2,FAM63A,MANF,ETV4,ZNF462,PGM1,SMARCA2,SHMT1,SLC37A1,KIF20A,COQ10B,OGDHL,PRICKLE1,GNAS,ONECUT1,KLF12,WIPI1,NRG1,KLF5,NRGN,RARG,NR3C2 |
| 2.192e-02 | -3.82 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | 182 | 27 | 17758 | 1761 |
MAN2B2,CCDC109B,CAST,COQ10B,TSC22D3,ITGA6,PIK3R1,LITAF,PTGER4,BTN3A1,TCF7,FAM46C,OPTN,FAM46A,SLC16A6,MGAT4A,IL6ST,KBTBD2,STK38,FAM117A,SFMBT1,ARRB1,FHL1,PPP2R2D,ARHGEF9,TOB1,SMAGP |
| 2.192e-02 | -3.82 | TGFB_UP.V1_UP | MSigDB lists | TGFB_UP.V1_UP | 182 | 27 | 17758 | 1761 |
CYP26B1,CDK17,ELK3,MMD,RUSC2,RAPGEF2,EPHA4,LMCD1,PDGFB,RNF19B,HTR1D,PDGFA,CTGF,FAT4,ETS2,PAIP2B,KCNN4,DACT1,SGK1,CCDC82,LTBP2,PIK3CD,F2RL1,COL16A1,PKIA,KLF7,ABCG1 |
| 2.192e-02 | -3.82 | GSE3982_EOSINOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_UP | 182 | 27 | 17758 | 1761 |
DLGAP1,LAMP2,CD55,UGT8,PACSIN2,NLRX1,CD63,TSC22D3,HLA-F,SYNE2,PPFIBP2,LITAF,RAB6A,ZFAND5,RHEB,FUCA1,ZNF75D,PTEN,SHC3,NMI,TMEM143,TPST1,FGD6,ARRB1,PTPRE,PTGES,HOXC13 |
| 2.195e-02 | -3.82 | regulation of intracellular transport | biological process | GO:0032386 | 568 | 73 | 16441 | 1675 |
LAMP1,TXN,THRA,TP53,ERBB2,IL18,PRKACA,BARD1,APC2,BCAP31,IER3,CALM2,NOV,CDH1,SP100,DACT1,CABP1,SIVA1,REEP1,ABCA2,TRPC1,DAB2IP,PDE4D,F2R,CHP1,SIRT1,ERLEC1,AKT1,NBPF3,EZR,PRKCQ,SLC25A5,SNX12,FZD7,PLCG1,INPP4B,NRG1,DDX58,TCAF1,BMF,PINK1,NFKBIE,BVES,UBASH3B,RAB23,PSMD10,CALM3,TGFBR1,IL18R1,BMP7,FAM20B,BAX,UBE2J1,SORL1,MDFIC,WNT3A,SYK,MDFI,HES1,RHOA,CALM1,PIK3R1,LITAF,CDK5R1,NUCB1,TMEM30A,NFKBIA,YOD1,GPER1,FZD5,PKIA,TMEM173,EHD1 |
| 2.196e-02 | -3.82 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | 36 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,TP53,PIK3CA,IDH1,GNA11 |
| 2.200e-02 | -3.82 | keratan sulfate metabolic process | biological process | GO:0042339 | 35 | 8 | 16441 | 1675 |
GNS,B3GNT7,SLC35D2,B3GNT2,GALNS,HEXB,B4GALT4,ST3GAL1 |
| 2.200e-02 | -3.82 | semaphorin-plexin signaling pathway | biological process | GO:0071526 | 35 | 8 | 16441 | 1675 |
SEMA6B,SEMA4D,PLXNA1,SEMA3G,SEMA3A,NRP2,SEMA3B,FARP2 |
| 2.200e-02 | -3.82 | activation of GTPase activity | biological process | GO:0090630 | 35 | 8 | 16441 | 1675 |
ARHGAP24,RASGRF1,CORO1C,SIPA1L1,SCRIB,EPHA1,RASGRP1,ARHGEF16 |
| 2.200e-02 | -3.82 | regulation of axon extension involved in axon guidance | biological process | GO:0048841 | 35 | 8 | 16441 | 1675 |
SEMA6B,SEMA4D,MEGF8,SEMA3G,PLXNA1,WNT3A,SEMA3A,SEMA3B |
| 2.200e-02 | -3.82 | YGTCCTTGR_UNKNOWN | MSigDB lists | YGTCCTTGR_UNKNOWN | 94 | 16 | 17758 | 1761 |
ARAP2,TRIM2,THRA,PRKACA,SNTA1,CXXC4,SYT7,STIM1,SYT13,MANF,ANO4,CITED2,ARMCX6,NDUFA12,SOCS5,IGSF3 |
| 2.201e-02 | -3.82 | negative regulation of gene expression | biological process | GO:0010629 | 1508 | 177 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,CNOT8,LMCD1,MORF4L2,CCNB1,HDAC6,PDGFB,BARD1,ERP29,CTGF,ZFP36,SIVA1,MITF,FOSB,DLG1,IRF2,CRY2,ZBTB18,TIPARP,MYBL1,CYP1B1,PLK1,THRB,SMARCA2,CD55,KCNIP3,TRIM8,ITCH,CBX6,TFAP2C,EZR,AGO4,LOXL2,PRKRA,AHRR,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,E2F8,RUNX2,CDKN1C,SERPINE2,SOX9,HES2,MECOM,ELF3,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,MDFIC,RFX5,PIM1,ETV7,NUP85,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,NUDT16,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,TOB1,RARG,NUP58,XDH,EGLN1,GAS2L1,FOXM1,THRA,TP53,TDRKH,OSR2,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,MYT1,NR2C1,CHP1,SIRT1,AKT1,DRAP1,ERBB2IP,H2AFV,SNX12,ARHGAP35,NFIX,RBL1,WFS1,PEX2,PTBP3,OVOL1,TLE1,NRG1,IRF7,KLF5,CBX7,GLIS3,PINK1,TNRC6C,NKX3-1,DEPDC1,CPEB4,DAP,PSMD10,NKRF,AES,FGF19,SIX4,FZD6,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,ITGB8,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CITED2,IQGAP3,CNOT6L,TRIM62,NCOA2,NFE2L3,TGIF1,HES1,IFITM3,GCLC,PPARA,PRICKLE1,RUNX3,BBS2,PITX2,BANK1,FGFR2,NR1D2,TBX18,NR4A3,ARRB1,HMGA1,GPER1,OSR1,SOX8,NDFIP1,CPEB2,AHR,ZBTB33,PKIA,JARID2 |
| 2.203e-02 | -3.82 | PLK2 and PLK4 events | Pathway Interaction DB | plk2_4pathway | 2 | 2 | 2227 | 331 |
PLK2,PLK4 |
| 2.205e-02 | -3.81 | V$SRF_Q5_01 | MSigDB lists | V$SRF_Q5_01 | 207 | 30 | 17758 | 1761 |
MYL9,SUN2,SLC2A4,SCOC,SERTAD4,ERBB2IP,GRK6,FOS,PPP2R3A,ABR,MAPKAPK2,FOXP2,TIMP3,SLC25A4,ITGB8,SLC16A6,CALD1,CORO1C,PELI2,MITF,FOSB,SLC4A3,CDKN1B,DUSP10,SGK1,DIXDC1,ARF6,CITED2,DGKG,ABCA1 |
| 2.208e-02 | -3.81 | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | 64 | 12 | 17758 | 1761 |
MDK,PGF,PPIF,ADD1,IGFBP6,CDK16,TMX4,SAT1,MYBL2,ERBB2,TRIM21,AES |
| 2.208e-02 | -3.81 | ST_FAS_SIGNALING_PATHWAY | MSigDB lists | ST_FAS_SIGNALING_PATHWAY | 64 | 12 | 17758 | 1761 |
CASP3,NFKBIE,RALBP1,NFKBIA,TP53,BAX,EZR,MAP3K5,HSPB1,MAPK8IP1,NCS1,FAS |
| 2.208e-02 | -3.81 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | 64 | 12 | 17758 | 1761 |
PLK1,PRSS23,CSF1,KLF9,HMGA1,SEPP1,ETV4,S100A2,PHLDA1,SGCB,ABCA1,CKS2 |
| 2.214e-02 | -3.81 | regulation of response to wounding | biological process | GO:1903034 | 386 | 52 | 16441 | 1675 |
SERPINE2,NLRX1,IL15,UBASH3B,EPHA4,ARFGEF1,IL18,TEC,SLC7A2,PDGFB,ETS1,GSTP1,IER3,CD109,PDGFA,NOV,ADORA1,FAM46A,PIK3AP1,PTEN,IL6ST,BCL6,PRKG1,DUSP10,TNFRSF12A,F2R,SYK,ENPP4,CD55,PSMB4,TNIP1,PBK,PLAUR,ANO6,PTGER4,PPARA,PRKCQ,F12,CASP4,ABR,SOCS3,PTPRF,GPRC5B,HPSE,CDK19,NR1D2,PLPP3,NOD2,STK39,GPER1,NDFIP1,F2RL1 |
| 2.219e-02 | -3.81 | negative regulation of macromolecule biosynthetic process | biological process | GO:0010558 | 1398 | 165 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,ZFP36,SIVA1,MITF,FOSB,PASK,DLG1,IRF2,CRY2,ZBTB18,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,TRIM8,ITCH,CBX6,TFAP2C,EZR,AGO4,LOXL2,PIF1,AHRR,ENPP1,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,MARCH8,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,MDFIC,RFX5,PIM1,ETV7,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,JAK3,TOB1,RARG,EGLN1,NF2,S100A11,FOXM1,THRA,INPP5D,TP53,OSR2,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,NR2C1,CHP1,SIRT1,DRAP1,ERBB2IP,RAD17,H2AFV,ARHGAP35,NFIX,RBL1,WFS1,PEX2,OVOL1,TLE1,NRG1,IRF7,KLF5,CBX7,GLIS3,TNRC6C,NKX3-1,DEPDC1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,GSTP1,FZD6,SIX4,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,RNF128,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CNOT6L,CITED2,TRIM62,NCOA2,NFE2L3,TGIF1,HES1,IFITM3,GCLC,PPARA,PRICKLE1,RUNX3,PITX2,BANK1,ACVRL1,NR1D2,FGFR2,NMI,TBX18,NR4A3,ARRB1,ITGAV,HMGA1,OSR1,SOX8,CPEB2,AHR,PKIA,ZBTB33,JARID2 |
| 2.226e-02 | -3.80 | DOANE_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_UP | 174 | 26 | 17758 | 1761 |
CLCN3,BCAM,PINK1,LGALS3,PDIA5,ARHGDIB,PRKAR2B,NENF,CNTNAP2,DNAH3,ALCAM,ENDOD1,SNTA1,ZNF432,GNB5,ELMO2,BMP7,RRBP1,TMC5,ARRB1,AHCY,FAR2,COBL,GM2A,MCCC2,ABCC1 |
| 2.226e-02 | -3.80 | GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN | MSigDB lists | GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN | 174 | 26 | 17758 | 1761 |
GAS2L1,HECA,SORBS1,PAPSS2,CRYM,MPP1,FXYD3,TRIB2,RASGRP2,CDKN2C,PLCH1,ONECUT1,SCNN1A,ATP1A1,PVRL2,SECTM1,KLF3,VAT1,WWP1,ECE1,TIAM1,ALS2CL,TPCN1,NCOA2,CD33,SEMA3B |
| 2.228e-02 | -3.80 | Import of palmitoyl-CoA into the mitochondrial matrix | REACTOME pathways | R-HSA-200425 | 11 | 4 | 8202 | 867 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 2.228e-02 | -3.80 | Signaling by FGFR4 in disease | REACTOME pathways | R-HSA-5655291 | 11 | 4 | 8202 | 867 |
PLCG1,GAB1,PIK3R1,PIK3CA |
| 2.231e-02 | -3.80 | TFAP2A (transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)) | protein interactions | 7020 | 46 | 10 | 16036 | 1726 |
CASP3,CITED4,EPAS1,MKRN3,SH3BP4,TP53,AURKA,WWP1,CITED2,WWP2 |
| 2.235e-02 | -3.80 | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | 36 | 8 | 17758 | 1761 |
GNAS,IL15,NFKBIA,HDAC1,WNT3A,CCNB1,CCNB2,FAS |
| 2.235e-02 | -3.80 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | MSigDB lists | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | 36 | 8 | 17758 | 1761 |
ARSG,HEXB,ASAH1,CTSA,GLA,ARSK,ARSB,GM2A |
| 2.235e-02 | -3.80 | V$ATF1_Q6 | MSigDB lists | V$ATF1_Q6 | 224 | 32 | 17758 | 1761 |
CCNI,PPM1J,THRA,TSC22D3,RET,HABP4,LMCD1,GABRG2,NANS,PDGFA,CCND1,AKIRIN1,IRF2BPL,CALD1,LMO4,FOSB,TNFRSF12A,KLF9,PDE4D,SEC23A,SPATA18,PTPRU,FOS,ZFAND5,COQ10A,SCG2,SYT13,CENPE,OSR1,GEM,MAFF,EHD1 |
| 2.243e-02 | -3.80 | human chr2p13.2 | chromosome location | human chr2p13.2 | 9 | 3 | 26250 | 1887 |
CYP26B1,EMX1,SMYD5 |
| 2.243e-02 | -3.80 | human chr11q14 | chromosome location | human chr11q14 | 9 | 3 | 26250 | 1887 |
RAB38,PRCP,SYTL2 |
| 2.244e-02 | -3.80 | Aurora B signaling | Pathway Interaction DB | aurora_b_pathway | 39 | 11 | 2227 | 331 |
RHOA,CENPA,KIF20A,TACC1,KLHL13,CDCA8,NDC80,KIF23,AURKA,BUB1,RASA1 |
| 2.246e-02 | -3.80 | LEIN_MIDBRAIN_MARKERS | MSigDB lists | LEIN_MIDBRAIN_MARKERS | 79 | 14 | 17758 | 1761 |
ENDOD1,CACHD1,TSC22D3,EIF5A2,STEAP2,ARRDC1,HMGA1,PANX2,SLC25A43,ARHGEF40,LTBP3,AFAP1,KCTD9,CD83 |
| 2.246e-02 | -3.80 | GHANDHI_BYSTANDER_IRRADIATION_UP | MSigDB lists | GHANDHI_BYSTANDER_IRRADIATION_UP | 79 | 14 | 17758 | 1761 |
PLA2G4A,GCLM,MCTP1,RNF128,POPDC3,SLC39A8,SLC16A6,SAT1,OSGIN2,NFKBIZ,EPB41L4B,C9orf72,AHR,PTGES |
| 2.251e-02 | -3.79 | virus receptor activity | molecular function | GO:0001618 | 70 | 13 | 16491 | 1673 |
LAMP1,PVRL4,SCARB2,CD55,IDE,PVRL2,SIVA1,AXL,CR2,F11R,ITGAV,NCAM1,DAG1 |
| 2.251e-02 | -3.79 | negative regulation of protein dephosphorylation | biological process | GO:0035308 | 77 | 14 | 16441 | 1675 |
CAMSAP3,SPRED1,LMTK3,SWAP70,PPP4R4,SEMA4D,CRY2,PKMYT1,DLG3,TIPRL,SH2D4A,SYTL2,ARFGEF3,CHP1 |
| 2.255e-02 | -3.79 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | 102 | 17 | 17758 | 1761 |
SHMT1,GCLC,POC1B,TRIB2,TYSND1,CDK1,CENPN,MDM1,DCK,RANBP1,FAM20B,OTUB2,AHCY,EIF4EBP2,DAB2IP,TRAF5,SEPHS1 |
| 2.257e-02 | -3.79 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | 166 | 25 | 17758 | 1761 |
SUSD3,ZWINT,CHCHD7,ADCK3,ACVR1C,CR2,EPHA1,TYSND1,SCML1,IGF1R,NGFRAP1,IL6ST,BDH1,CDCA7L,PASK,SPINT2,TPST1,CD9,FAM102A,PIK3CD,SOX8,NDFIP1,KLF7,ARHGEF4,LAMP3 |
| 2.257e-02 | -3.79 | RECEPTOR_ACTIVITY | MSigDB lists | RECEPTOR_ACTIVITY | 548 | 69 | 17758 | 1761 |
BCAM,IL15RA,THRA,RET,IL27RA,PLXNA1,ITPR2,DNER,SLC20A1,DDR1,GRM5,HTR1D,SIVA1,IL6ST,IL31RA,CLDN4,TACSTD2,SCARA3,F2R,PTPRE,TRAM1,NR2C1,MED30,THRB,FZD4,ACVR1C,PTPRU,PTGER4,ROR1,ITPR3,FZD7,PTPRJ,PTK7,AXL,ANXA9,F2RL1,LIFR,NR3C2,ABCA1,HLA-F,HLA-E,GABRG2,TGFBR1,MERTK,FZD6,NRP2,LGALS3BP,M6PR,CXCL16,IGF1R,RRBP1,SORL1,ERBB3,MMD,NR3C1,AMFR,CNTNAP1,PTPRF,GABRD,SEMA4D,ACVRL1,PVRL2,ITPR1,RYK,NR4A3,FZD5,RARG,AHR,CD33 |
| 2.257e-02 | -3.79 | Cysteine Metabolism | SMPDB pathways | SMP00013 | 9 | 4 | 978 | 131 |
GOT1,GCLM,GCLC,CTH |
| 2.257e-02 | -3.79 | Cystinosis- ocular nonnephropathic | SMPDB pathways | SMP00722 | 9 | 4 | 978 | 131 |
GCLM,GOT1,GCLC,CTH |
| 2.257e-02 | -3.79 | Beta-mercaptolactate-cysteine disulfiduria | SMPDB pathways | SMP00499 | 9 | 4 | 978 | 131 |
GOT1,GCLM,GCLC,CTH |
| 2.262e-02 | -3.79 | Aldosterone-regulated sodium reabsorption | KEGG pathways | hsa04960 | 39 | 9 | 6908 | 758 |
ATP1A1,SCNN1A,PIK3R1,PIK3CA,SGK1,PIK3CD,ATP1B1,ATP1B3,NR3C2 |
| 2.262e-02 | -3.79 | Aldosterone-regulated sodium reabsorption | KEGG pathways | ko04960 | 39 | 9 | 6908 | 758 |
ATP1A1,SCNN1A,PIK3R1,PIK3CA,SGK1,PIK3CD,ATP1B1,ATP1B3,NR3C2 |
| 2.264e-02 | -3.79 | central_nervous_system-brain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_I | 43 | 9 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,IDH1,GNA11 |
| 2.266e-02 | -3.79 | ampulla_of_Vater | COSMIC cancer mutations | ampulla_of_Vater | 50 | 10 | 17775 | 1757 |
GNAS,MAN2B2,CDH1,AKT1,IQCE,PIK3CA,TP53,ANXA9,BLVRA,SCN3A |
| 2.275e-02 | -3.78 | CENTROSOME | MSigDB lists | CENTROSOME | 57 | 11 | 17758 | 1761 |
TOP2A,PLK1,PCGF5,DLGAP5,CNTRL,NEK2,CEP41,NDE1,ESPL1,SAC3D1,NIN |
| 2.275e-02 | -3.78 | EXTRACELLULAR_MATRIX_PART | MSigDB lists | EXTRACELLULAR_MATRIX_PART | 57 | 11 | 17758 | 1761 |
COL9A3,SGCE,COL13A1,SNTB2,COL18A1,COL7A1,COL4A5,ERBB2IP,SNTB1,SGCB,COL16A1 |
| 2.275e-02 | -3.78 | GTGTCAA,MIR-514 | MSigDB lists | GTGTCAA,MIR-514 | 57 | 11 | 17758 | 1761 |
CCNE2,TRIM2,PTEN,NR3C1,FZD4,FAM117A,VAT1,PIK3C2B,RNF19B,ARHGEF9,SCN3A |
| 2.275e-02 | -3.78 | GNF2_CDC27 | MSigDB lists | GNF2_CDC27 | 57 | 11 | 17758 | 1761 |
FECH,GCLM,CA2,ERMAP,GCLC,BLVRB,EIF2AK1,MINPP1,SPTB,TRAK2,RAD23A |
| 2.275e-02 | -3.78 | MCCC1 (methylcrotonoyl-CoA carboxylase 1) | protein interactions | 56922 | 16 | 5 | 16036 | 1726 |
KIF5B,IFIT1,LGALS3,CUL4B,MCCC2 |
| 2.275e-02 | -3.78 | PRKRIR (protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)) | protein interactions | 5612 | 16 | 5 | 16036 | 1726 |
DDX58,TACC1,DNAJC3,PASK,TP53 |
| 2.275e-02 | -3.78 | PDGFA (platelet-derived growth factor alpha polypeptide) | protein interactions | 5154 | 16 | 5 | 16036 | 1726 |
PDGFA,PLCG1,HSPG2,COL6A1,FURIN |
| 2.275e-02 | -3.78 | IGF1 (insulin-like growth factor 1 (somatomedin C)) | protein interactions | 3479 | 16 | 5 | 16036 | 1726 |
NOV,IGFBP2,IDE,IGF1R,IGFBP6 |
| 2.275e-02 | -3.78 | MYO7A (myosin VIIA) | protein interactions | 4647 | 16 | 5 | 16036 | 1726 |
VEZT,CDH1,MAP2,MYRIP,CALM1 |
| 2.275e-02 | -3.78 | SYTL4 (synaptotagmin-like 4) | protein interactions | 94121 | 16 | 5 | 16036 | 1726 |
SYTL4,CEP70,RAB27B,ZBTB7B,STX3 |
| 2.279e-02 | -3.78 | Rac GTPase binding | molecular function | GO:0048365 | 42 | 9 | 16491 | 1673 |
DOCK4,RALBP1,IQGAP1,CORO1C,EPS8,STRADB,NCKAP1,PKN1,ITPKA |
| 2.279e-02 | -3.78 | aminopeptidase activity | molecular function | GO:0004177 | 42 | 9 | 16491 | 1673 |
PRCP,CTSV,ERAP1,F12,DPP8,RNPEP,LTA4H,ERAP2,METAP2 |
| 2.283e-02 | -3.78 | T cell receptor signaling pathway | biological process | GO:0050852 | 146 | 23 | 16441 | 1675 |
RIPK2,PSMB4,THEMIS2,INPP5D,PSME2,PIK3R1,BTN3A1,PSMD10,PSME1,PRKCQ,TEC,CACNB4,BCAR1,PSMA4,PLCG1,PTPRJ,PSMD1,PTEN,NFKBIA,PLCG2,PIK3CA,PIK3CD,PDE4D |
| 2.288e-02 | -3.78 | Prolactin Signaling Pathway | WikiPathways | WP2037 | 75 | 15 | 4455 | 516 |
IRS2,PIAS3,CASP3,RPS6KA2,AKT1,JAK1,NFKBIA,PIK3R1,PIK3CA,ERBB2,TEC,ELK1,FOS,SIRPA,SOCS3 |
| 2.292e-02 | -3.78 | CRK (v-crk avian sarcoma virus CT10 oncogene homolog) | protein interactions | 1398 | 184 | 29 | 16036 | 1726 |
GFPT1,KCNIP3,PLSCR1,CAST,UBASH3B,RET,PIK3R1,PPFIBP2,ERBB2,NANS,SPR,BCAR1,REPS1,SH3KBP1,LMNA,IRS2,WEE1,IGF1R,SH3BP1,CORO1C,DOK4,PIK3CA,SERPINB6,BUB1,PIK3C2B,PIK3CD,ERBB3,HSPB1,GAB1 |
| 2.295e-02 | -3.77 | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_DN | 191 | 28 | 17758 | 1761 |
ENPP4,LMO7,GCA,B3GNT2,TCTN2,PSME2,HLA-E,NUB1,VWA1,CD274,CD40,ARHGEF40,ETS1,SPTLC2,TNFSF9,ARF4,PLEKHG6,ANKRD6,NAT1,ELF5,ITPR1,IRF2,ALDH7A1,STK39,PIM1,ST3GAL1,TIAM1,ATG4D |
| 2.295e-02 | -3.77 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP | 191 | 28 | 17758 | 1761 |
HECA,CD55,MRC2,HLA-E,GALNT12,ATP8A1,HLA-F,ITGA6,LITAF,BTN3A1,SNN,FAM46C,CRISPLD2,SLC25A36,RNF220,FAM46A,ANKRD6,SLC16A6,MGAT4A,KBTBD2,NFKBIA,TPST1,BCL6,ANKRD12,ZNF165,PPP2R2D,TOB1,NCOA2 |
| 2.295e-02 | -3.77 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP | 191 | 28 | 17758 | 1761 |
MAP3K3,PLA2G4A,LAMP2,S100A4,STAT4,SH3BGRL,TCF7,CTSZ,GGH,IFIT3,DHRS3,DDR1,B4GALNT1,IRS2,H1F0,TIMM8A,SEMA4D,PLK2,AIM1,ALDH1A3,ABCB1,TRIM21,MDFIC,CNOT6L,LTA4H,NDUFA12,S100A6,WBP5 |
| 2.295e-02 | -3.77 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_DN | 191 | 28 | 17758 | 1761 |
TM2D2,SEC61B,PLAUR,SWI5,KCTD12,ISYNA1,OAT,SDC1,CDK1,C3orf58,SNX12,CYB5A,GLCE,PRKAG2,RPL12,BDH1,DBI,OPN3,POF1B,MRPS28,TMEM37,TINAGL1,RNF26,GAD1,S100A6,KLF7,ABCC1,METAP2 |
| 2.295e-02 | -3.77 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 191 | 28 | 17758 | 1761 |
ADD1,PLAUR,DNAJB2,MPP1,SELL,PSME1,NPC2,GRK6,MORF4L2,MGST2,C15orf39,FAM101B,SESN1,DAG1,ANKRD10,RPS6KA2,ETS2,CDK16,IL6ST,LMO4,NAT1,KCNN4,NR4A3,FAM102A,ARRB1,SERPINI1,MPHOSPH9,NR2C1 |
| 2.295e-02 | -3.77 | GSE17721_POLYIC_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDM_DN | 191 | 28 | 17758 | 1761 |
ELK3,RHOA,FAM169A,HJURP,TESK1,ACO1,FAM133B,FTH1,GDF15,GTF3A,SLC7A2,CYB5A,APPBP2,ARHGEF10L,ARHGAP24,DNAJC10,RNF128,ADRBK1,WIPI1,XYLT2,LMO4,AKR1B1,MRPS28,MANF,ECE1,RNF26,MYO5A,ABCC1 |
| 2.295e-02 | -3.77 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 191 | 28 | 17758 | 1761 |
LAMP2,MPP1,DAP,ABCG2,KIF23,MGST2,GRK6,ZFAND5,FAM101B,SESN1,DAG1,CYB5A,ANKRD10,IGF1R,ETS2,RALGPS2,GATA2,CDK16,WFS1,IL6ST,CD9,HDAC1,TRIM21,RCAN3,MPHOSPH9,AHR,KLF7,JARID2 |
| 2.295e-02 | -3.77 | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | 191 | 28 | 17758 | 1761 |
CPD,ARHGAP11A,PTPN9,NDC80,ERI2,UBE2A,MIER3,NUSAP1,PRKAR2B,PDK3,SNN,ANLN,PSMA4,KLHL2,GRHL1,RAB11FIP2,SHC3,UEVLD,NEK2,EXOC8,AURKA,NFKBIZ,SPCS3,LRP11,MYBL1,TIAM1,MELK,NXT2 |
| 2.295e-02 | -3.77 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | 191 | 28 | 17758 | 1761 |
SUSD3,LAMP2,ANXA3,LGALS3,PLSCR1,AK7,LPGAT1,C1GALT1C1,TDRKH,PSME1,RAB6A,POMGNT1,RNF19B,C11orf95,NCS1,FRMD4B,GNPTAB,PEX2,MATN2,CEP78,RYK,PPP2R3C,MLKL,GEM,DLG3,F2R,MED30,AHR |
| 2.295e-02 | -3.77 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 191 | 28 | 17758 | 1761 |
PMPCB,PGM1,CLCN3,MRPL44,PLSCR1,GUSB,SH3BGRL,HTATIP2,NUSAP1,BLVRA,LACTB2,CRABP2,ALCAM,PRDX4,MESDC2,GABARAPL1,PSMD1,TIMM8A,SIVA1,PGRMC1,NEK2,BUB1,MDFIC,AHCY,LMAN1,PDIA6,NUP85,S100A6 |
| 2.296e-02 | -3.77 | myelin sheath | cellular component | GO:0043209 | 165 | 25 | 17570 | 1756 |
FAM213B,MBP,ENO2,PDIA3,ERBB2,EZR,SCRIB,MPP5,ATP1B1,ITPR3,SLC25A5,CNTNAP1,ATP1A1,SLC25A4,CA2,GNB5,PTEN,DPYSL2,DLG1,AKR1B1,MDH1,PITPNA,MYH14,PACSIN1,ARF6 |
| 2.302e-02 | -3.77 | response to toxic substance | biological process | GO:0009636 | 170 | 26 | 16441 | 1675 |
PLA2G4A,CASP3,PINK1,MBP,NQO1,CASP9,GRIN1,TP53,SLC1A3,CCNB1,HDAC6,FOS,ETS1,SDC1,HTR1D,FAS,FECH,CYP1A1,CDH1,JAK1,DHRS2,CST3,BAX,CDKN1B,AHR,CYP1B1 |
| 2.302e-02 | -3.77 | negative regulation of cell cycle phase transition | biological process | GO:1901988 | 170 | 26 | 16441 | 1675 |
PLK1,PSMB4,PSME2,CTDSPL,CDC20,TP53,RGCC,PSMD10,PSME1,PSMA4,CDK1,FANCI,IER3,SUSD2,JADE1,CCND1,E2F7,PSMD1,PTEN,DACT1,OVOL1,CDKN1B,BUB1,FHL1,UBE2C,CTDSP2 |
| 2.307e-02 | -3.77 | SMITH_LIVER_CANCER | MSigDB lists | SMITH_LIVER_CANCER | 43 | 9 | 17758 | 1761 |
TOP2A,PPP2R5A,HJURP,PEX2,PGRMC1,HTATIP2,AURKA,TOB1,NCOA2 |
| 2.307e-02 | -3.77 | KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | MSigDB lists | KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | 43 | 9 | 17758 | 1761 |
GFPT1,PGM1,CMAS,UGP2,UAP1,GNPDA1,GNE,HEXB,NANS |
| 2.307e-02 | -3.77 | HUANG_FOXA2_TARGETS_UP | MSigDB lists | HUANG_FOXA2_TARGETS_UP | 43 | 9 | 17758 | 1761 |
ENPP1,MCTP1,MAP2,CLIP4,CADPS2,NRG1,F2R,MAFF,LAMP3 |
| 2.307e-02 | -3.77 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | MSigDB lists | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | 43 | 9 | 17758 | 1761 |
RASGRF1,ARHGEF3,ARHGEF11,TIAM1,ARHGEF9,ABR,ARHGEF16,FGD1,ARHGEF4 |
| 2.307e-02 | -3.77 | PID_THROMBIN_PAR1_PATHWAY | MSigDB lists | PID_THROMBIN_PAR1_PATHWAY | 43 | 9 | 17758 | 1761 |
RHOA,PIK3R1,PIK3CA,ARRB1,PKN1,F2R,PLCB2,GNA11,ADRBK2 |
| 2.307e-02 | -3.77 | GNATENKO_PLATELET_SIGNATURE | MSigDB lists | GNATENKO_PLATELET_SIGNATURE | 43 | 9 | 17758 | 1761 |
GNAS,CD99,HLA-E,PGRMC1,FTH1,HLA-C,TAGLN2,NRGN,MYL12A |
| 2.307e-02 | -3.77 | PID_TCPTP_PATHWAY | MSigDB lists | PID_TCPTP_PATHWAY | 43 | 9 | 17758 | 1761 |
JAK1,CSF1,PIK3R1,PIK3CA,PIK3CD,LMAN1,PDGFB,JAK3,GAB1 |
| 2.307e-02 | -3.77 | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 43 | 9 | 17758 | 1761 |
IGF1R,PTK7,AXL,RYK,ROR1,ERBB3,DDR1,MERTK,NRP2 |
| 2.307e-02 | -3.77 | PID_INTEGRIN3_PATHWAY | MSigDB lists | PID_INTEGRIN3_PATHWAY | 43 | 9 | 17758 | 1761 |
CYR61,PLAUR,SDC4,F11R,COL4A5,ITGAV,PDGFB,SDC1,L1CAM |
| 2.307e-02 | -3.77 | B Cell Receptor Signaling Pathway | WikiPathways | WP23 | 158 | 27 | 4455 | 516 |
RHOA,AKT1,INPP5D,RPS6KA1,PIK3R1,CASP9,PIP4K2C,CR2,PRKCQ,TEC,ITPR2,DUSP4,ELK1,BCAR1,RASA1,MAPKAPK2,PLCG1,BANK1,PIK3AP1,PLCG2,NFKBIA,ITPR1,BCL6,BAX,ARPC2,SYK,GAB1 |
| 2.308e-02 | -3.77 | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-squamous_cell_carcinoma | 72 | 13 | 17775 | 1757 |
CACHD1,AKT1,PTEN,PIK3R1,NBPF3,PIK3CA,TP53,ERBB2,ALDH7A1,NOTCH3,IDH1,FANCI,DEF6 |
| 2.310e-02 | -3.77 | parathyroid-carcinoma | COSMIC cancer mutations | parathyroid-carcinoma | 311 | 42 | 17775 | 1757 |
ANXA3,FAM92A1,HLA-F,CARD10,DENND2D,FANCI,CDKN2C,TNS3,TMEM87B,KCNN4,COL6A1,PRKG1,ABCA2,PIK3CA,TMBIM6,ALPK1,ERBB3,RAB27B,LRP11,NEB,CKAP4,MCTP1,COG2,CYB5R2,OXR1,GRIN1,ACO1,NFE2L1,ITPR3,RHEB,COL12A1,CD83,GNAS,JAK1,COL13A1,ABCB1,PRDM5,PCDH19,REEP4,IFIH1,ABCA1,DEF6 |
| 2.311e-02 | -3.77 | peptide antigen binding | molecular function | GO:0042605 | 29 | 7 | 16491 | 1673 |
HLA-B,TAPBP,HLA-C,HLA-E,HLA-F,HLA-A,TAP1 |
| 2.313e-02 | -3.77 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | 50 | 10 | 17758 | 1761 |
IL15,PLK2,AXL,RGS20,DUSP10,GEM,ITPR3,AHR,ATP2B1,CYP1B1 |
| 2.313e-02 | -3.77 | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | MSigDB lists | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | 50 | 10 | 17758 | 1761 |
CDKN2C,WEE1,FOXM1,CDC20,AURKA,UBE2C,KIF11,BARD1,CDK1,PRIM1 |
| 2.314e-02 | -3.77 | V$ATF4_Q2 | MSigDB lists | V$ATF4_Q2 | 250 | 35 | 17758 | 1761 |
LTBP1,BMF,SORBS1,TSC22D3,NDRG2,TIPRL,FAM167A,AKIRIN1,IRF2BPL,CXCL16,ZNF687,STIM1,LMO4,FOSB,ABCA2,SGK1,ABCD1,RFX5,PDE4D,RASGEF1A,PTPRU,CAPN6,PRICKLE1,FOS,ZFAND5,CDK5R1,GNAS,PITX2,TMEM54,NR4A3,NR4A2,CENPE,GEM,AHR,PKIA |
| 2.316e-02 | -3.77 | V$ATF6_01 | MSigDB lists | V$ATF6_01 | 118 | 19 | 17758 | 1761 |
SEC23A,SPATA18,NR4A1,DNAJB2,NANS,DUSP4,ZFAND5,ARF4,PITX2,COQ10A,LMO4,MADD,TRPC1,TWIST1,TSPAN13,KLF9,SEMA3B,GOLGB1,KDELR1 |
| 2.323e-02 | -3.76 | Metabolism of nitric oxide | REACTOME pathways | R-HSA-202131 | 22 | 6 | 8202 | 867 |
CALM2,CALM3,AKT1,SPR,CALM1,ZDHHC21 |
| 2.323e-02 | -3.76 | eNOS activation and regulation | REACTOME pathways | R-HSA-203765 | 22 | 6 | 8202 | 867 |
CALM2,CALM3,AKT1,SPR,CALM1,ZDHHC21 |
| 2.327e-02 | -3.76 | ACACTAC,MIR-142-3P | MSigDB lists | ACACTAC,MIR-142-3P | 126 | 20 | 17758 | 1761 |
TMEM200B,SYPL1,SPRED1,MMD,TMEM55B,TGFBR1,LRRC1,MORF4L2,FNDC3A,TP53INP2,PSIP1,LLGL2,MGAT4A,SGK1,ITGAV,ACSL4,TIPARP,CPEB2,RARG,C9orf72 |
| 2.327e-02 | -3.76 | AGGGCAG,MIR-18A | MSigDB lists | AGGGCAG,MIR-18A | 134 | 21 | 17758 | 1761 |
EMX1,TIMP2,NF2,TACC1,CIT,TMEM55B,CALM1,ETV5,FURIN,ARL4C,CALM3,BCL2L1,TRIB2,DAG1,IL17RB,CALM2,GATA2,LHX6,TLN2,CITED2,CBX7 |
| 2.327e-02 | -3.76 | SMID_BREAST_CANCER_ERBB2_UP | MSigDB lists | SMID_BREAST_CANCER_ERBB2_UP | 134 | 21 | 17758 | 1761 |
CPD,PRODH,PLEKHA6,PAPSS2,SLC37A1,NQO1,ATP2C2,ERBB2,CYB561,IL13RA1,SPTLC2,ALCAM,MMP15,NCOA3,SCNN1A,TMC5,AIM1,GOT1,C2orf72,TSPAN1,SNPH |
| 2.330e-02 | -3.76 | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | 217 | 31 | 17775 | 1757 |
NCKAP5,CELSR2,NF2,AKT1,ESRP1,SYNE2,RET,PIK3R1,TP53,ERBB2,ATP8B3,CNTNAP2,IDH1,CASP4,VPS26A,GNAS,DOPEY2,ADD3,CDH1,PTEN,GATA2,FGFR2,LIMK1,PIK3CA,SH3BP4,LIMCH1,ITGAV,RCAN3,JAK3,PLCB2,COL16A1 |
| 2.330e-02 | -3.76 | atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | atypical_teratoid-rhabdoid_tumour | 217 | 31 | 17775 | 1757 |
NCKAP5,CELSR2,NF2,AKT1,ESRP1,PIK3R1,SYNE2,RET,TP53,ERBB2,ATP8B3,CNTNAP2,IDH1,CASP4,VPS26A,GNAS,DOPEY2,ADD3,CDH1,FGFR2,PTEN,GATA2,LIMK1,SH3BP4,PIK3CA,LIMCH1,ITGAV,RCAN3,JAK3,PLCB2,COL16A1 |
| 2.336e-02 | -3.76 | forelimb morphogenesis | biological process | GO:0035136 | 42 | 9 | 16441 | 1675 |
RUNX2,FMN1,HOXA9,TFAP2A,TWIST1,OSR2,OSR1,CRABP2,MECOM |
| 2.337e-02 | -3.76 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 183 | 27 | 17758 | 1761 |
CASP3,ORAI2,ADD1,PQLC3,TACC1,LPGAT1,TMX4,NUB1,MTL5,STMN3,KCTD12,NTAN1,FAM101B,STK17B,IRF2BPL,MARCH8,NOV,ADD3,SNX18,ZNRF2,METTL7A,RAB11FIP1,CCDC69,HDAC1,LRRK1,MAP3K5,MYO5A |
| 2.337e-02 | -3.76 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | 183 | 27 | 17758 | 1761 |
DYNLRB1,BMF,FAM92A1,CHCHD7,CKAP2,PCBP3,CNOT8,SDC4,UBE2A,C5orf30,CDCA2,LYNX1,GTF2A2,TP53INP2,KIF5B,MDM1,CDKN2AIPNL,CST3,NETO2,TUBG1,CLDN4,RTKN2,CTDSP2,MED30,ZBTB33,WBP5,METAP2 |
| 2.337e-02 | -3.76 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | 183 | 27 | 17758 | 1761 |
CPD,ANXA3,CASP3,SEC61B,MMD,FRMD4A,IL15RA,LGR4,CELSR2,PLSCR1,NLRX1,RUNX3,TGFBR1,VARS2,HMGN3,GGH,LPIN3,BARD1,ALCAM,GABARAPL1,AHRR,SWAP70,ITPR1,RYK,DLG3,TBC1D4,HOOK1 |
| 2.337e-02 | -3.76 | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | 183 | 27 | 17758 | 1761 |
PLA2G4A,PRKAA2,CLCN3,TNIP1,NLRX1,RALBP1,C5orf30,PBX3,IFIT3,NUP62CL,BMP2K,SIRPA,DCP2,GNS,TIMP3,SLC27A6,SCG2,PRCP,NAT1,TMEM30A,DBI,PAPSS1,TRIOBP,RYK,SPCS3,NCOA2,KDELR1 |
| 2.337e-02 | -3.76 | nitric-oxide synthase binding | molecular function | GO:0050998 | 17 | 5 | 16491 | 1673 |
CALM3,CALM2,SNTA1,SCN5A,CALM1 |
| 2.338e-02 | -3.76 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | 293 | 40 | 17758 | 1761 |
MYL9,SLC2A4,SORBS1,TSC22D3,LMCD1,DNER,TSPAN7,BEX2,HDAC9,SUSD2,FOXP2,SIPA1L2,CALD1,FLRT3,REEP1,IGFBP2,TLN2,NCAM1,CITED2,MMD,S100A4,PIK3R1,COL7A1,DNAJB14,MUM1L1,SLCO4A1,CACHD1,BANK1,HLF,PDLIM3,SLC4A4,FGFR2,WIPI1,ISM1,CGREF1,EIF4EBP2,FHL1,TANC2,PKIA,PROM2 |
| 2.352e-02 | -3.75 | Nectin adhesion pathway | Pathway Interaction DB | nectin_pathway | 25 | 8 | 2227 | 331 |
CDH1,PVRL2,IQGAP1,PIK3R1,PIK3CA,F11R,ITGAV,FARP2 |
| 2.353e-02 | -3.75 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | 488 | 62 | 17775 | 1757 |
LTBP1,NF2,ATP8A1,ETV5,TMX4,TP53,NRG2,TDRKH,CNTNAP2,FAM46C,KREMEN1,ANO1,CDS1,SLC25A36,FOXP2,CCND1,MDM1,FRY,FAM189A1,SHC3,PTEN,ANKFN1,AOX1,PRKG1,PIK3CA,ATRNL1,SLC44A2,CACNA1D,TMEM37,PIKFYVE,MYO5B,CHSY3,RASGRF1,RAB3B,PIK3R1,OGDHL,UTRN,MAML2,LDB2,IDH1,PTGFRN,ZBTB7B,BBS2,DOCK5,SFXN5,ARHGEF26,FAS,NIN,NEIL1,FAT4,JAK1,PDLIM3,PLOD2,ZNF704,PRDM5,SH3BGRL2,GRAMD1C,SYT13,NR3C2,COL16A1,PCSK5,KLF7 |
| 2.358e-02 | -3.75 | THUM_SYSTOLIC_HEART_FAILURE_UP | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_UP | 389 | 51 | 17758 | 1761 |
LAMP1,PLA2G4A,CTHRC1,MRPL44,PACSIN2,SCOC,SERPINE2,CNOT8,EPHA4,MIER3,PKP2,FAM198B,PHLDA1,SRPX2,M6PR,DIRAS3,SS18,CTSC,ANKRD12,HLA-C,LMAN1,SCARA3,PDIA6,SGCB,CRTAP,SYPL1,PDGFC,B3GNT2,RHOA,UTRN,BTN3A2,EZR,HTATIP2,ARHGDIB,ZFAND5,LEPR,FAS,MAPKAPK2,ARHGAP24,SCARB2,UEVLD,KBTBD2,PLK2,TSPAN18,PGRMC1,ERAP1,EFNA5,LTBP2,ARF6,RARG,ARHGEF9 |
| 2.360e-02 | -3.75 | placenta blood vessel development | biological process | GO:0060674 | 29 | 7 | 16441 | 1675 |
HES1,HS6ST1,FZD5,ITGB8,AKT1,CYR61,SOCS3 |
| 2.360e-02 | -3.75 | response to iron ion | biological process | GO:0010039 | 29 | 7 | 16441 | 1675 |
CCND1,SLC11A2,CYP1A1,CCNB1,CYBRD1,TFAP2A,ACO1 |
| 2.360e-02 | -3.75 | positive regulation of cartilage development | biological process | GO:0061036 | 29 | 7 | 16441 | 1675 |
LOXL2,RUNX2,CYR61,ACVRL1,POR,SOX9,BMP1 |
| 2.360e-02 | -3.75 | regulation of extracellular matrix organization | biological process | GO:1903053 | 29 | 7 | 16441 | 1675 |
MFI2,ETS1,DDR1,DAG1,CST3,SOX9,RGCC |
| 2.362e-02 | -3.75 | TMEM171 (transmembrane protein 171) | protein interactions | 134285 | 53 | 11 | 16036 | 1726 |
SLC25A24,GPRC5B,MOSPD2,CKAP2,ITCH,ADIPOR1,SLC7A2,TTYH3,TPCN1,CMTM4,OCLN |
| 2.362e-02 | -3.75 | PTTG1 (pituitary tumor-transforming 1) | protein interactions | 9232 | 53 | 11 | 16036 | 1726 |
CASP3,PPP2R5A,PTTG1,CDC20,TP53,AURKA,EZR,GPER1,ESPL1,CDK1,RAD23A |
| 2.362e-02 | -3.75 | UHRF2 (ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase) | protein interactions | 115426 | 53 | 11 | 16036 | 1726 |
TFAP4,CCND1,TRIM8,TP53,BAX,HDAC1,BCL2L1,CCNB1,JAK3,BCAR1,CDK1 |
| 2.363e-02 | -3.75 | GPCRKINASE | prints domains | PR00717 | 7 | 3 | 4759 | 462 |
GRK6,ADRBK1,ADRBK2 |
| 2.363e-02 | -3.75 | response to acid chemical | biological process | GO:0001101 | 294 | 41 | 16441 | 1675 |
PRKAA2,CASP3,CPEB4,SOX9,RET,COL18A1,SELL,BCL2L1,CCNB1,PDGFB,SP100,CTGF,COL6A1,CD9,TFAP2A,AKR1B1,TMBIM6,CDKN1B,IGFBP2,LRP11,WNT3A,CDKN2D,PDGFC,SHMT1,RHOA,AKT1,FZD4,MICB,YES1,PDK3,FZD7,GNAS,TIMP3,PTK7,SH3BP4,OSR1,RARG,ABCA1,COL16A1,PTGES,RRAGD |
| 2.363e-02 | -3.75 | MODULE_308 | MSigDB lists | MODULE_308 | 72 | 13 | 17758 | 1761 |
SMARCA2,SETDB2,DEPDC1,CDKN1C,FOXM1,SH3BP1,PTPN9,MYBL2,GTF2F2,ATP8B3,PHKA2,CCNB1,ZBTB33 |
| 2.363e-02 | -3.75 | WARTERS_RESPONSE_TO_IR_SKIN | MSigDB lists | WARTERS_RESPONSE_TO_IR_SKIN | 72 | 13 | 17758 | 1761 |
DDB2,E2F7,BTG3,FRMD4A,DRAM1,GDF15,FAM198B,SESN1,ALCAM,ETV7,GM2A,TMEM173,FAS |
| 2.366e-02 | -3.74 | Heparan sulfate/heparin (HS-GAG) metabolism | REACTOME pathways | R-HSA-1638091 | 54 | 11 | 8202 | 867 |
B3GALT6,HS6ST1,SLC35D2,HPSE,HSPG2,GUSB,SDC4,HS3ST3B1,SDC1,NDST3,GLCE |
| 2.371e-02 | -3.74 | organic acid catabolic process | biological process | GO:0016054 | 211 | 31 | 16441 | 1675 |
CYP26B1,PRODH,SHMT1,ALDH6A1,AASS,CRYM,CPT2,HAL,LPIN3,OAT,AMDHD1,CYP4F3,CYP39A1,CYP26A1,ALDH5A1,ACADSB,ABHD12,FAAH,PEX2,PCYOX1,ECI2,ALDH7A1,ABCD1,AHCY,GOT1,ACOX2,GAD1,MCCC2,ACOT7,FAH,CTH |
| 2.371e-02 | -3.74 | carboxylic acid catabolic process | biological process | GO:0046395 | 211 | 31 | 16441 | 1675 |
CYP26B1,PRODH,SHMT1,ALDH6A1,AASS,CRYM,CPT2,HAL,LPIN3,OAT,AMDHD1,CYP4F3,CYP39A1,CYP26A1,ALDH5A1,ACADSB,ABHD12,FAAH,PEX2,PCYOX1,ECI2,ALDH7A1,ABCD1,AHCY,GOT1,ACOX2,GAD1,MCCC2,ACOT7,FAH,CTH |
| 2.373e-02 | -3.74 | CTSC (cathepsin C) | protein interactions | 1075 | 11 | 4 | 16036 | 1726 |
CTSL,FBXO6,CTSC,CAPN1 |
| 2.373e-02 | -3.74 | NPC1 (Niemann-Pick disease, type C1) | protein interactions | 4864 | 11 | 4 | 16036 | 1726 |
MRPS28,FBXO6,LGR4,TMEM173 |
| 2.373e-02 | -3.74 | IL6R (interleukin 6 receptor) | protein interactions | 3570 | 11 | 4 | 16036 | 1726 |
ERAP1,WWP1,IL6ST,WWP2 |
| 2.373e-02 | -3.74 | CCNB1IP1 (cyclin B1 interacting protein 1, E3 ubiquitin protein ligase) | protein interactions | 57820 | 11 | 4 | 16036 | 1726 |
PRKAA2,CCNB1,NF2,CDK1 |
| 2.373e-02 | -3.74 | GUCY1A2 (guanylate cyclase 1, soluble, alpha 2) | protein interactions | 2977 | 11 | 4 | 16036 | 1726 |
SNTA1,ERBB2IP,DLG3,DLG1 |
| 2.373e-02 | -3.74 | PIGK (phosphatidylinositol glycan anchor biosynthesis class K) | protein interactions | 10026 | 11 | 4 | 16036 | 1726 |
FBXO6,ALPP,ULBP2,LYPD3 |
| 2.373e-02 | -3.74 | MTMR6 (myotubularin related protein 6) | protein interactions | 9107 | 11 | 4 | 16036 | 1726 |
AMOTL2,ZWINT,RARG,NMI |
| 2.373e-02 | -3.74 | MICALL1 (MICAL-like 1) | protein interactions | 85377 | 11 | 4 | 16036 | 1726 |
PACSIN2,PACSIN1,SH3KBP1,EHD1 |
| 2.373e-02 | -3.74 | AZGP1 (alpha-2-glycoprotein 1, zinc-binding) | protein interactions | 563 | 11 | 4 | 16036 | 1726 |
NUF2,ITGAV,CDK19,ABCC1 |
| 2.373e-02 | -3.74 | CDC14A (cell division cycle 14A) | protein interactions | 8556 | 11 | 4 | 16036 | 1726 |
PLK1,CCNB1,KIF20A,TP53 |
| 2.373e-02 | -3.74 | GLS2 (glutaminase 2 (liver, mitochondrial)) | protein interactions | 27165 | 11 | 4 | 16036 | 1726 |
SNTA1,DLG3,RGS3,DLG1 |
| 2.373e-02 | -3.74 | regulation of lipid biosynthetic process | biological process | GO:0046890 | 123 | 20 | 16441 | 1675 |
PRKAA2,SIRT1,SORBS1,AKT1,IDH1,PDGFB,POR,FGF19,PLIN5,GPLD1,PDGFA,PRKAG2,ATP1A1,MID1IP1,IGF1R,CYR61,PEX2,SLC27A1,GPER1,ABCG1 |
| 2.374e-02 | -3.74 | CAGCTG_V$AP4_Q5 | MSigDB lists | CAGCTG_V$AP4_Q5 | 1429 | 164 | 17758 | 1761 |
LTBP1,TXN,PPM1J,TSC22D3,ARFGEF1,NRG2,F11R,PJA2,PDGFB,CHPF,PLS3,CALM2,CDKN2C,PQLC2,STIM1,CABP1,PASK,SLC44A1,MITF,KCNS3,ANKRD12,IQCD,TINAGL1,TRAM1,BTBD3,NEB,SMARCA2,KCNIP3,TRIM8,RGAG1,CBX6,TFAP2C,TNS1,PTGFRN,RNF19B,LHFPL2,ARF4,ABR,PGF,CXXC4,MDK,KLF12,NKD1,BMP1,RRAGD,PRKAA2,SCN5A,BMF,PARP12,ITGA6,FXYD3,ZCCHC24,ETV5,CALM3,NDUFA4,DHRS3,S100A2,TNFRSF19,PSIP1,TFAP4,ITGA3,IGF1R,PIK3AP1,MEGF8,ATP5H,FLRT3,FRAS1,ZRANB1,SLC12A2,PLCB2,PLEKHA6,CALM1,MYBL2,TCF7,TP53INP2,EPN3,H1F0,MFSD2A,AGBL5,RHOBTB2,CDK18,MAP3K5,DRP2,HOOK1,TOB1,DOCK9,CCNE2,NCKAP5,SPRED1,SORBS1,REPS2,DDIT4L,CAST,HDAC11,SNN,PRKACA,DDR1,REPS1,APPBP2,SYTL2,SH3BP1,DACT1,LMO4,REEP1,BCL6,CDH3,CDKN1B,VAT1,ACSL4,RASGEF1A,MYT1,SULT2B1,DOCK4,MAP3K3,MBP,AKT1,PRKCQ,DUSP4,ITPR3,NFIX,PTK7,KLF5,NR3C2,IER5L,TNRC6C,IGFBP6,CPEB4,ETS1,BEX2,PPP2R3A,NRP2,HDAC9,IRF2BPL,ADRBK1,PHF7,ITGB8,CD9,FAM63A,SLC44A2,ERBB3,CITED2,TRIM62,TPCN1,DLGAP1,ADAMTS2,TGIF1,TACC1,NR4A1,PRICKLE1,RUNX3,COL7A1,AIF1L,MAPK8IP1,ARHGAP24,RYK,NR4A3,GRIN2D,LRRK1,GEM,ZMIZ1,OSR1,L1CAM,ZBTB33,SNPH |
| 2.376e-02 | -3.74 | oligosaccharide metabolic process | biological process | GO:0009311 | 63 | 12 | 16441 | 1675 |
MAN2A2,GAA,B3GALNT1,MGAT4A,GNPTAB,HEXB,MGAT4B,FUT8,GLA,ST3GAL1,NAGA,GM2A |
| 2.376e-02 | -3.74 | negative regulation of transporter activity | biological process | GO:0032410 | 63 | 12 | 16441 | 1675 |
CALM2,PPIF,GNB5,CABP1,CALM1,CALM3,CAB39,TWIST1,STK39,ANO9,NDFIP1,WWP2 |
| 2.376e-02 | -3.74 | purine nucleoside bisphosphate biosynthetic process | biological process | GO:0034033 | 17 | 5 | 16441 | 1675 |
ACACB,PAPSS2,PAPSS1,PANK1,ACOT7 |
| 2.376e-02 | -3.74 | ribonucleoside bisphosphate biosynthetic process | biological process | GO:0034030 | 17 | 5 | 16441 | 1675 |
ACACB,PAPSS2,PAPSS1,PANK1,ACOT7 |
| 2.376e-02 | -3.74 | mitochondrial calcium ion homeostasis | biological process | GO:0051560 | 17 | 5 | 16441 | 1675 |
MCUR1,CCDC109B,SLC8B1,BCAP31,SLC25A27 |
| 2.376e-02 | -3.74 | myelin assembly | biological process | GO:0032288 | 17 | 5 | 16441 | 1675 |
CNTNAP1,MPP5,UGT8,PIKFYVE,CD9 |
| 2.376e-02 | -3.74 | negative regulation of NF-kappaB import into nucleus | biological process | GO:0042347 | 17 | 5 | 16441 | 1675 |
PSMD10,NOV,BMP7,NFKBIA,LITAF |
| 2.376e-02 | -3.74 | branching involved in salivary gland morphogenesis | biological process | GO:0060445 | 17 | 5 | 16441 | 1675 |
PLXNA1,FGFR2,SEMA3A,BMP7,DAG1 |
| 2.376e-02 | -3.74 | negative regulation of release of cytochrome c from mitochondria | biological process | GO:0090201 | 17 | 5 | 16441 | 1675 |
PPIF,PSMD10,BCL2L1,AKT1,LMNA |
| 2.376e-02 | -3.74 | metanephric nephron epithelium development | biological process | GO:0072243 | 17 | 5 | 16441 | 1675 |
HES1,OSR1,SOX8,LGR4,SOX9 |
| 2.376e-02 | -3.74 | nucleoside bisphosphate biosynthetic process | biological process | GO:0033866 | 17 | 5 | 16441 | 1675 |
ACACB,PAPSS2,PAPSS1,PANK1,ACOT7 |
| 2.376e-02 | -3.74 | metanephric tubule development | biological process | GO:0072170 | 17 | 5 | 16441 | 1675 |
HES1,OSR1,SOX8,LGR4,SOX9 |
| 2.376e-02 | -3.74 | renal system process involved in regulation of blood volume | biological process | GO:0001977 | 17 | 5 | 16441 | 1675 |
ADORA1,PDGFB,EMP2,F2R,F2RL1 |
| 2.376e-02 | -3.74 | interferon-gamma production | biological process | GO:0032609 | 17 | 5 | 16441 | 1675 |
BTN3A1,BTN3A2,IL18,RNF19B,F2RL1 |
| 2.376e-02 | -3.74 | ATACCTC,MIR-202 | MSigDB lists | ATACCTC,MIR-202 | 175 | 26 | 17758 | 1761 |
LAMP2,MMD,GRHL2,CPEB4,CAPN6,ZC3H11A,LPGAT1,ZKSCAN2,DNAJB11,FAM101B,DNAJB9,DPYSL3,CCND1,SLC25A4,RAB11FIP2,CSNK1G1,CALD1,PCDH19,FAR2,MYRIP,GAD1,SCYL3,CPEB2,NDST3,CRTAP,STARD3NL |
| 2.376e-02 | -3.74 | MTOR_UP.V1_DN | MSigDB lists | MTOR_UP.V1_DN | 175 | 26 | 17758 | 1761 |
LTBP1,SLC2A4,PRSS23,ADCK3,PDIA5,PTGER4,BBS2,H1FX,IRS2,PDGFA,PDLIM3,ARTN,NR1D2,SLC44A1,CRY2,ARL4D,NCAM1,WBSCR27,ICOSLG,SCARA3,SULT2B1,LIFR,ABCA1,OSGIN1,FAH,XDH |
| 2.380e-02 | -3.74 | carboxylic acid metabolic process | biological process | GO:0019752 | 864 | 106 | 16441 | 1675 |
PLA2G4A,ACACB,UGT8,UGP2,AASS,CRYM,CPT2,VARS2,SLC7A2,MGST2,LPIN3,OAT,CYP39A1,CYP26A1,CYP1A1,CYP2S1,ALDH1A3,FABP6,SRR,SERINC2,GOT1,ACSL4,ACOX2,TECR,EGLN3,CTH,GPX4,CYP1B1,PANK1,ACO1,PRKAR2B,GLO1,ICMT,IDH1,MRPS36,CYP4F3,POR,ALDH5A1,ABHD12,UEVLD,P4HA2,PEX2,DHTKD1,SLC27A1,ADIPOR1,CYP2U1,LTA4H,SLC27A3,ST3GAL1,PRKAA2,GCLM,CMAS,FAM213B,ENO2,ALDH6A1,HAL,GNE,SLC1A3,CRABP2,DSE,SPR,SGPL1,SLC27A6,PCYOX1,ATP8B1,ECI2,AHCY,ABCD1,ALDH7A1,GAD1,SYK,NCOA2,CRTAP,MCCC2,MYO5A,ABCC1,FAH,CYP26B1,GFPT1,FADS2,PGM1,PRODH,SHMT1,PLSCR1,GCLC,ELOVL3,ERO1A,OGDHL,PPARA,GGH,PDK3,RNPEP,AMDHD1,CYB5A,PRDX4,MAPKAPK2,PRKAG2,SLC6A6,ACADSB,FAAH,NR4A3,MDH1,PTGES,OCLN,ACOT7,EGLN1 |
| 2.384e-02 | -3.74 | APEH (acylaminoacyl-peptide hydrolase) | protein interactions | 327 | 40 | 9 | 16036 | 1726 |
LAMP2,SHMT1,SERPINE2,DNM1L,NMI,TBCD,CTTN,H1FX,VPS26A |
| 2.391e-02 | -3.73 | CYTOSOL | MSigDB lists | CYTOSOL | 200 | 29 | 17758 | 1761 |
SEC23A,SHMT1,PEX6,PIK3R1,ACO1,CDA,EZR,PRICKLE1,NUCB2,AIFM2,IDH1,AIP,VPS26A,ATG4A,ARHGEF10L,RGS3,ZFP36,STEAP2,NOD2,BAX,TACSTD2,SERPINB6,MDH1,ANXA9,RAP1GAP,AIFM3,CCDC88A,ATG4D,EGLN1 |
| 2.391e-02 | -3.73 | PAL_PRMT5_TARGETS_UP | MSigDB lists | PAL_PRMT5_TARGETS_UP | 200 | 29 | 17758 | 1761 |
CD99,COL6A2,KIF20A,FIGNL1,GUSB,CDC20,CALM1,ABCG2,KIF23,CALM3,INTS8,H2AFV,SLC25A5,KIF11,NFIB,PSIP1,TSEN34,RASA1,PRIM1,CALM2,RBL1,PRKCDBP,AHCY,NDE1,NCAM1,CCNB2,NUP85,CYP1B1,CKS2 |
| 2.394e-02 | -3.73 | kidney morphogenesis | biological process | GO:0060993 | 85 | 15 | 16441 | 1675 |
CTNNBIP1,HES1,FAT4,LGR4,FMN1,NPNT,FRAS1,SOX9,DLG1,TACSTD2,SOX8,NPHP3,OSR1,ADAMTS16,GCNT1 |
| 2.396e-02 | -3.73 | astrocytoma_Grade_II | COSMIC cancer mutations | astrocytoma_Grade_II | 633 | 78 | 17775 | 1757 |
ARHGAP11A,MTM1,NF2,HSPG2,PPM1J,RET,TP53,ERBB2,TDRKH,PLXNA1,TYMP,MUC16,ZNF687,ARTN,STIM1,CYP4F11,IQCE,PIK3CA,ZDHHC23,RTKN2,GLB1L2,NOTCH3,NR2C1,RASGRP1,SCN3A,TRIM8,AKT1,CAPN6,UTRN,PRKRA,IDH1,POR,HS6ST1,JAK1,ATP7B,SPTBN5,RGS14,NXT2,CDK17,MRC2,FRMD4A,PYROXD2,ASAH1,DNAH3,FAM167A,M6PR,DOPEY2,RNF128,ADRBK1,IGSF9,PTEN,ALPP,MEGF8,TPST1,ARVCF,MAPK11,PIM1,IQGAP3,CCDC88A,RIMS2,PARP9,ACBD5,PCDH1,KLK5,ERMAP,MFSD2B,PIK3R1,RC3H2,NPHP3,FNDC3A,GNA11,GNAS,TJP3,NLRC5,CSTF2,CPEB2,ESYT2,TMEM131 |
| 2.402e-02 | -3.73 | DENN | smart domains | SM00799 | 16 | 5 | 9131 | 997 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 2.402e-02 | -3.73 | CARD | smart domains | SM00114 | 16 | 5 | 9131 | 997 |
CARD8,RIPK2,CASP4,CASP9,NOD2 |
| 2.402e-02 | -3.73 | dDENN | smart domains | SM00801 | 16 | 5 | 9131 | 997 |
ST5,SBF1,DENND2D,MADD,DENND5B |
| 2.405e-02 | -3.73 | regulation of lymphocyte apoptotic process | biological process | GO:0070228 | 56 | 11 | 16441 | 1675 |
IRS2,LGALS3,PTEN,TSC22D3,BCL6,TP53,BAX,PRKCQ,CD274,SLC39A10,JAK3 |
| 2.405e-02 | -3.73 | positive regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001244 | 56 | 11 | 16441 | 1675 |
SIRT1,NKX3-1,BMF,DNM1L,TP53,BAX,PLEKHF1,BUB1,BCL2L1,PRKRA,BCAP31 |
| 2.407e-02 | -3.73 | - | gene3d domains | 3.40.800.20 | 11 | 4 | 9988 | 1080 |
HDAC1,HDAC6,HDAC11,HDAC9 |
| 2.409e-02 | -3.73 | human chr7p21.1 | chromosome location | human chr7p21.1 | 16 | 4 | 26250 | 1887 |
TSPAN13,ITGB8,MACC1,HDAC9 |
| 2.409e-02 | -3.73 | human chr6q14.1 | chromosome location | human chr6q14.1 | 16 | 4 | 26250 | 1887 |
SH3BGRL2,HMGN3,LCA5,TMEM30A |
| 2.409e-02 | -3.73 | human chr3q22.3 | chromosome location | human chr3q22.3 | 16 | 4 | 26250 | 1887 |
MRAS,FAIM,CEP70,DZIP1L |
| 2.411e-02 | -3.73 | CAHOY_ASTROGLIAL | MSigDB lists | CAHOY_ASTROGLIAL | 95 | 16 | 17758 | 1761 |
FBLN5,PRSS23,LGALS3,PQLC3,ATP8A1,MORC4,PKP2,LOXL2,LPIN3,FAS,CD109,TNFRSF12A,CTTN,TMEM37,LTBP2,SEMA3B |
| 2.413e-02 | -3.72 | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | 167 | 25 | 17758 | 1761 |
RMND5A,MAN2B2,COQ10B,DNAJC3,ITGA6,DGKQ,EPHA4,HABP4,ASAH1,TRIB2,LDB2,DNAJB9,CD83,GABARAPL1,IRS2,MARCH8,COQ10A,SGK1,NR4A2,NFKBIZ,KLF11,MARCH2,MAP3K5,ZNF502,PCSK5 |
| 2.413e-02 | -3.72 | ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | ADENYL_NUCLEOTIDE_BINDING | 167 | 25 | 17758 | 1761 |
PINK1,PEX6,GCLC,ABCG2,TP53,TGFBR1,PIF1,AIFM2,MAP3K6,STK17B,DGKE,ABCD4,STK17A,DAPK2,ACVRL1,ATP7B,STK38,ABCA2,DAPK1,ABCB1,PIM1,MAP3K5,ABCC1,SEPHS1,ABCG1 |
| 2.413e-02 | -3.72 | SNF5_DN.V1_UP | MSigDB lists | SNF5_DN.V1_UP | 167 | 25 | 17758 | 1761 |
IER5L,KIF20A,CKAP2,GTF3A,FBXO6,ATP1B1,GRK6,FBLN1,LGALS3BP,CD109,TAPBP,SLC6A6,RBL1,SCG2,SEMA4D,CORO1C,CD9,PRKCDBP,ERAP1,GOT1,BUB1,IFIT1,NDE1,NCAPG2,UBE2C |
| 2.417e-02 | -3.72 | TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 372 | 49 | 17758 | 1761 |
LASP1,SCN5A,SLC2A4,FXYD3,SLC25A13,ABCG2,SLC1A3,SLC7A2,ITPR2,CACNB4,SLC20A1,SLC9A2,SLC9A7,ABCD4,KCNN4,SLC16A6,SLC44A1,KCNS3,SLC44A2,ATP8B1,TRPC1,CACNA1D,SCN2A,SLC12A2,ATP2B1,ABCC1,CLCN3,KCNJ12,SEC61B,SLC11A2,ATP1B1,ITPR3,SLC25A5,STEAP1,CYB5A,TAPBP,SLC6A6,ATP1A1,KCNMB4,SLC25A4,SLC4A4,KCNK1,ATP7B,SLC9A6,ITPR1,SLC4A3,ATP1B3,SHROOM2,ABCG1 |
| 2.422e-02 | -3.72 | negative regulation of cellular macromolecule biosynthetic process | biological process | GO:2000113 | 1310 | 155 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,ZFP36,SIVA1,MITF,FOSB,PASK,DLG1,IRF2,CRY2,ZBTB18,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,ITCH,CBX6,TFAP2C,EZR,AGO4,LOXL2,PIF1,AHRR,ENPP1,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,MDFIC,RFX5,PIM1,ETV7,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,JAK3,TOB1,RARG,EGLN1,NF2,S100A11,FOXM1,THRA,TP53,OSR2,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,NR2C1,CHP1,SIRT1,DRAP1,ERBB2IP,RAD17,H2AFV,NFIX,ARHGAP35,RBL1,WFS1,PEX2,OVOL1,TLE1,NRG1,IRF7,KLF5,CBX7,GLIS3,TNRC6C,NKX3-1,DEPDC1,CPEB4,DAP,PSMD10,NKRF,AES,FZD6,SIX4,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CNOT6L,CITED2,NCOA2,NFE2L3,TGIF1,HES1,GCLC,PPARA,PRICKLE1,RUNX3,PITX2,BANK1,ACVRL1,NR1D2,FGFR2,TBX18,NR4A3,ARRB1,HMGA1,OSR1,SOX8,CPEB2,AHR,PKIA,ZBTB33,JARID2 |
| 2.423e-02 | -3.72 | CELL_DEVELOPMENT | MSigDB lists | CELL_DEVELOPMENT | 568 | 71 | 17758 | 1761 |
CASP3,NF2,TP53,BCL2L1,AIFM2,BARD1,TNFSF9,IER3,DAPK2,CDKN2C,ARTN,SIVA1,BCL6,CDKN1B,F2R,CDKN2D,SEMA3B,MX1,AKT1,ACVR1C,S100A4,CASP9,HTATIP2,GLO1,STK17B,CDK1,CASP4,OPTN,SOCS3,DNM1L,MADD,HDAC1,AIFM3,HSPB1,MAPK12,BMF,CIT,DAP,NCKAP1,ADAMTSL4,GSTP1,NRP2,SGPL1,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BMP7,BAX,DAPK1,CD70,PIM1,FARP2,DPYSL5,GCLC,PARP4,RUNX3,BCAR1,CDK5R1,RASA1,STK17A,FAS,SCG2,SEMA4D,NFKBIA,MAP3K5,ESPL1,HIPK3,AHR,IFI6 |
| 2.423e-02 | -3.72 | INSR (insulin receptor) | protein interactions | 3643 | 95 | 17 | 16036 | 1726 |
PRKAA2,SORBS1,CALM1,PIK3R1,CALM3,RASA1,SOCS3,PTPRF,IRS2,ENPP1,PLCG1,IGF1R,JAK1,DOK4,IRF7,HMGA1,GAB1 |
| 2.423e-02 | -3.72 | SLC39A4 (solute carrier family 39 (zinc transporter), member 4) | protein interactions | 55630 | 95 | 17 | 16036 | 1726 |
GOLIM4,ATP9A,MRS2,POMGNT1,EFNB1,ATP13A2,MAN2A2,ABHD12,FUT8,TMEM143,GLB1L2,ABCD1,C1orf43,FAR2,TMEM120A,MGAT5,CKAP4 |
| 2.425e-02 | -3.72 | WANG_CLIM2_TARGETS_UP | MSigDB lists | WANG_CLIM2_TARGETS_UP | 217 | 31 | 17758 | 1761 |
SEMA6B,ACACB,TRIM8,REPS2,S100A11,BVES,MRS2,COL18A1,CYB561,BCL2L1,MERTK,ALCAM,MYL12A,LEPR,COL12A1,RAVER2,PTPRF,CD109,DNAJC10,TAPBP,TIMP3,ANKS6,BMP7,PLK4,KLK7,IGFBP2,NPTXR,LMAN1,F2RL1,NAGA,IGSF3 |
| 2.425e-02 | -3.72 | Etoposide Action Pathway | SMPDB pathways | SMP00442 | 18 | 6 | 978 | 131 |
TOP2A,DNAJB11,PDIA6,ERP29,ABCB1,PDIA4 |
| 2.425e-02 | -3.72 | Etoposide Metabolism Pathway | SMPDB pathways | SMP00601 | 18 | 6 | 978 | 131 |
TOP2A,DNAJB11,PDIA6,ERP29,ABCB1,PDIA4 |
| 2.427e-02 | -3.72 | axon part | cellular component | GO:0033267 | 174 | 26 | 17570 | 1756 |
BIN1,CLCN3,MBP,SEPT6,CALB2,EPHA4,GRIN1,CNTNAP2,ELK1,DAG1,CNTNAP1,ADORA1,SYT7,FLRT3,SLC9A6,DPYSL2,DLG1,AURKA,DAB2IP,GOT1,NRG1,GPER1,SCN2A,PACSIN1,COBL,L1CAM |
| 2.437e-02 | -3.71 | regulation of cell shape | biological process | GO:0008360 | 139 | 22 | 16441 | 1675 |
WASF3,FBLIM1,ARAP3,BVES,STRIP2,EPS8,HEXB,EZR,DAG1,SH3KBP1,RASA1,ARHGAP35,SEMA4D,SHROOM3,CSNK1G1,ITGA7,DLG1,FGD6,MYH14,S100A13,MYL12B,FGD1 |
| 2.439e-02 | -3.71 | - | gene3d domains | 1.10.472.10 | 40 | 9 | 9988 | 1080 |
CCNE2,CCNI,CCND1,RBL1,CCNJL,CCNB1,CCNF,CCNB2,CDK5R1 |
| 2.440e-02 | -3.71 | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 928 | 110 | 17775 | 1757 |
GAS2L1,SLC35D2,BCAM,NCKAP5,KIAA1462,CRYM,GALNT12,CCDC110,ATP2C2,RET,FHDC1,TP53,ERBB2,PKP2,ITPR2,PLXNA1,DDR1,DNER,PDGFA,SS18,CYP1A1,STIM1,STEAP2,PIK3CA,ANKRD12,PHKA2,TLN2,TSPAN1,TIAM1,MGAT5,NR2C1,NEB,SULF2,ZNF462,SPEF2,CELSR2,AKT1,PTPRU,SYNE2,UTRN,RGAG1,NUSAP1,TNS1,C15orf39,IDH1,DOCK5,COL12A1,ATP13A2,KDM4D,MAN2A2,MFAP3L,HS6ST1,WFS1,ATP7B,LRIG1,SIPA1L1,SECTM1,MADD,RAB11FIP1,OVOL1,UNC5B,ABCA1,SCN5A,ARHGEF3,CDK17,RUNX2,CHCHD7,TBC1D1,LRP4,DGKQ,SLC25A27,OSGIN2,NKRF,NTAN1,DNAH3,PARM1,TEAD3,AIM1L,FUT2,IGF1R,LLGL2,MEGF8,KLF9,PIKFYVE,IQGAP3,DGKG,MED22,IGSF3,ERMAP,LONRF3,RC3H2,PIK3R1,GRIN1,ATP8B3,RNPEP,PLIN5,PRX,KLHL2,FECH,AP1AR,SWAP70,COQ10A,FGFR2,CGREF1,EGFL7,PLIN3,WDR62,TOB1,GOLGB1,JARID2 |
| 2.441e-02 | -3.71 | LYN (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 4067 | 216 | 33 | 16036 | 1726 |
CASP3,UGP2,TRIP10,INPP5D,TP53,TEC,TTYH3,SH2D4A,SH3KBP1,RASSF8,PLCG2,ADAM15,CDKN1B,PDE4D,SYK,RIMS2,DVL2,LAMP2,PLAUR,CASP9,ERO1A,CBX6,PRKCQ,BCAR1,CDK1,RASA1,PLCG1,BANK1,PLEKHH2,FGFR2,ITPR1,LNP1,OCLN |
| 2.441e-02 | -3.71 | GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN | 192 | 28 | 17758 | 1761 |
MAP3K3,GAS2L1,AMOTL2,PCOLCE,TIMP2,RALBP1,ARMC7,CCNF,DHRS3,RNF19B,STK17B,SRPX2,RANBP9,CYP26A1,ARHGAP24,IRS2,EPN3,WEE1,PPP2R5A,FUT2,GDE1,ZFP36,FAM114A1,PRKG1,MLKL,NCAPG2,TRAK2,TMEM131 |
| 2.441e-02 | -3.71 | GSE17721_CTRL_VS_CPG_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDM_DN | 192 | 28 | 17758 | 1761 |
RAB3B,UGT8,CYS1,PRICKLE1,IGSF8,CD40,PHLDA1,STK17B,KREMEN1,FOXL1,REPS1,ELF3,UAP1,PVRL2,WIPI1,LLGL2,RPL39,SLC44A1,PLK4,KLF5,CITED2,PTPRE,ST3GAL1,SNX10,PTGES,RARG,JARID2,EHD1 |
| 2.441e-02 | -3.71 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | 192 | 28 | 17758 | 1761 |
NFE2L3,ANXA3,DLGAP5,FOXM1,PBK,PTTG1,FTH1,GGH,PDK3,PHLDA1,BMP2K,KCTD9,BTG3,WIPI1,RANBP1,NEK2,AKR1B1,AURKA,BUB1,MANF,SERPINB1,CCNB2,APOBEC3G,ESPL1,ACOT7,MYO5A,FAH,CKS2 |
| 2.441e-02 | -3.71 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN | 192 | 28 | 17758 | 1761 |
PRKAA2,CPEB4,USP18,BLVRB,SYNE2,NDC80,GRIN1,C5orf30,HDAC6,FBLN1,CDK1,KCTD9,EPN3,DUOX1,CARHSP1,HS6ST1,NOV,ADORA1,KIAA1107,WIPI1,TRIM69,SLC16A6,MFSD2A,ELF5,TRIOBP,C10orf54,WNT3A,E2F8 |
| 2.441e-02 | -3.71 | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | 192 | 28 | 17758 | 1761 |
GFPT1,ATL1,TMEM68,GOLIM4,FBLN5,BCL9,USP18,RUSC2,GDF15,IGSF8,ANLN,FOS,STIL,PHLDA1,TNFSF9,M6PR,SOCS3,IER3,PHLPP2,ZFP36,NFKBIA,SGK1,FAM102A,NFKBIZ,PIM1,TRAF5,SCN3A,PARP9 |
| 2.441e-02 | -3.71 | GSE339_CD4POS_VS_CD8POS_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_DN | 192 | 28 | 17758 | 1761 |
PMPCB,SEC61B,TXN,MRPS15,GCLC,FRMD6,ITGA6,PLEKHO1,LITAF,PDIA3,MRAS,STX3,CMTM7,DNAJC10,SCARB2,TIMP3,DDOST,NPNT,ITPR1,SGK1,ARRB1,RPN2,MANF,ATP1B3,TRAM1,SMYD5,C9orf72,NAGA |
| 2.441e-02 | -3.71 | GSE17721_POLYIC_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_4H_BMDM_UP | 192 | 28 | 17758 | 1761 |
DPYSL5,S100A11,CHCHD7,GCLC,RALBP1,HTATIP2,CAMK1D,PJA2,BARD1,PSIP1,EPS8L2,FUCA1,DNAJC10,ZNF823,FRYL,DOLPP1,PELI2,SECTM1,SORL1,SGK1,TSPAN13,RELL1,MINPP1,RAP1GAP,GAB1,NAGA,PRR15,ABCG1 |
| 2.441e-02 | -3.71 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | 192 | 28 | 17758 | 1761 |
CPD,NFE2L3,PRODH,NQO1,BCL9,EPS8,FHDC1,TNS1,PSME1,NCKAP1,TRIB2,PHLPP1,DDR1,LHFPL2,PRRG4,PPP2R3A,FAS,NFIX,EPCAM,IGF1R,PIK3CA,S100A5,ZDHHC23,RAB11FIP1,MAP3K5,EGLN3,ZMYM1,IFIH1 |
| 2.441e-02 | -3.71 | CELL_CYCLE_PROCESS | MSigDB lists | CELL_CYCLE_PROCESS | 192 | 28 | 17758 | 1761 |
PLK1,REC8,SUN2,ZWINT,DLGAP5,CDKN1C,CIT,NDC80,KIF23,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,SAC3D1,CDKN2C,CDCA5,NEK2,TUBG1,AURKA,CDKN1B,BUB1,CENPE,NDE1,CDKN2D,UBE2C,MPHOSPH9,ESPL1 |
| 2.441e-02 | -3.71 | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | 192 | 28 | 17758 | 1761 |
GCA,ADD1,THRA,ITGA6,PTTG1,PIP4K2C,KIF23,ASAH1,NUSAP1,INTS8,MCFD2,OAT,DOCK5,LBR,EFNB1,DGKE,EFR3A,AMMECR1,TBX18,FAM20B,RHOBTB2,TACSTD2,TMOD2,RCAN3,DGKG,ABCA1,NUP85,MYL12B |
| 2.441e-02 | -3.71 | GSE27786_BCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_BCELL_VS_MONO_MAC_DN | 192 | 28 | 17758 | 1761 |
HJURP,ASPM,CDC20,CCDC34,GGH,EPHA1,PKMYT1,PRKRA,RNF19B,LHFPL2,TMPRSS4,TEAD3,ZNF469,CYP26A1,OPTN,KLHL2,MID1IP1,RBM47,CORO1C,FAM63A,NETO2,ARRB1,SERPINB6,RP2,IQGAP3,CITED2,E2F8,ARHGEF4 |
| 2.443e-02 | -3.71 | Glycerolipid metabolism | KEGG pathways | hsa00561 | 59 | 12 | 6908 | 758 |
DGKH,ALDH2,AGPAT2,PLPP3,DGKQ,AKR1B1,ALDH7A1,GLA,LPIN3,DGKG,ALDH3A2,DGKE |
| 2.443e-02 | -3.71 | Glycerolipid metabolism | KEGG pathways | ko00561 | 59 | 12 | 6908 | 758 |
DGKH,ALDH2,AGPAT2,PLPP3,DGKQ,AKR1B1,ALDH7A1,GLA,LPIN3,DGKG,ALDH3A2,DGKE |
| 2.444e-02 | -3.71 | Signaling by Wnt | REACTOME pathways | R-HSA-195721 | 326 | 46 | 8202 | 867 |
TNRC6C,LGR4,PSME2,SOX9,PSMD10,CALM3,AES,PSME1,ITPR2,KREMEN1,FZD6,VPS26A,CALM2,CTNNBIP1,PSMD1,GNB5,DACT1,PRKG1,WNT3A,PLCB2,DVL2,RHOA,PSMB4,AKT1,FZD4,BCL9,AMER1,CALM1,PRICKLE1,AGO4,TCF7,SCRIB,PYGO1,ROR1,ITPR3,PSMA4,FZD7,SOX13,CXXC4,PPP2R5A,ITPR1,RYK,TLE1,HDAC1,FZD5,RNF146 |
| 2.447e-02 | -3.71 | positive regulation of blood vessel endothelial cell migration | biological process | GO:0043536 | 23 | 6 | 16441 | 1675 |
PLCG1,AKT1,PDGFB,HSPB1,SRPX2,HDAC9 |
| 2.447e-02 | -3.71 | multicellular organismal reproductive behavior | biological process | GO:0033057 | 23 | 6 | 16441 | 1675 |
THRB,GRN,PTEN,THRA,HEXB,GRIN1 |
| 2.447e-02 | -3.71 | polysaccharide catabolic process | biological process | GO:0000272 | 23 | 6 | 16441 | 1675 |
CALM3,CALM2,PGM1,GAA,PHKA2,CALM1 |
| 2.447e-02 | -3.71 | negative regulation of muscle contraction | biological process | GO:0045932 | 23 | 6 | 16441 | 1675 |
DOCK4,PDE5A,ADORA1,ADRBK1,DOCK5,PRKG1 |
| 2.447e-02 | -3.71 | cellular component maintenance | biological process | GO:0043954 | 23 | 6 | 16441 | 1675 |
PKP2,CAMSAP3,CTTN,ITGA3,ITPKA,SHROOM2 |
| 2.447e-02 | -3.71 | regulation of voltage-gated calcium channel activity | biological process | GO:1901385 | 23 | 6 | 16441 | 1675 |
CALM3,CALM2,GNB5,CACNB4,CABP1,CALM1 |
| 2.447e-02 | -3.71 | leukocyte apoptotic process | biological process | GO:0071887 | 23 | 6 | 16441 | 1675 |
CTSL,PKN1,AKT1,SIVA1,FAS,BAX |
| 2.447e-02 | -3.71 | peptide catabolic process | biological process | GO:0043171 | 23 | 6 | 16441 | 1675 |
ERAP1,ECE1,IDE,LTA4H,RNPEP,ERAP2 |
| 2.447e-02 | -3.71 | renal system process involved in regulation of systemic arterial blood pressure | biological process | GO:0003071 | 23 | 6 | 16441 | 1675 |
ADORA1,PDGFB,EMP2,F2R,F2RL1,PCSK5 |
| 2.447e-02 | -3.71 | lysosome localization | biological process | GO:0032418 | 23 | 6 | 16441 | 1675 |
PIK3CD,HDAC6,GATA2,S100A13,RASGRP1,NR4A3 |
| 2.448e-02 | -3.71 | salivary_gland-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenoid_cystic_carcinoma | 507 | 64 | 17775 | 1757 |
SLC25A24,HSPG2,TRIP10,TP53,ERBB2,SLC9A7,CALM2,TYMP,SIPA1L2,MUC16,MUC4,SP100,LHX6,PIK3CA,ANKRD12,BRI3,ACOX2,LRP11,MYBL1,ERAP2,ZNF462,SMARCA2,TNIP1,SERTAD4,ERBB2IP,IDH1,NFIX,DUOX1,PTPRJ,OVOL1,IRF7,KLF5,TANC2,AIFM3,TNRC6C,ZNF395,CHCHD7,NOTUM,FOXP2,ITGB8,PTEN,FRAS1,OPN3,PRKG1,TFAP2A,IGFBP2,MPHOSPH9,ARAP2,ARHGEF28,ELOVL3,SPATA13,BTN3A2,COL7A1,RNPEP,NFIB,FAT4,SEMA4D,FGD6,CENPE,OSR1,ZMIZ1,L1CAM,TOB1,ADAMTS16 |
| 2.451e-02 | -3.71 | inner ear development | biological process | GO:0048839 | 179 | 27 | 16441 | 1675 |
HES1,CTHRC1,SOX9,SDC4,SLC25A27,SCRIB,PLPPR4,TMC1,SIX4,FZD6,ABR,PLS3,MAPKAPK2,FAT4,FGFR2,GATA2,PTK7,ALDH1A3,LRIG1,TBX18,TFAP2A,NR4A3,CDKN1B,ATP8B1,WNT3A,SPRY2,DVL2 |
| 2.454e-02 | -3.71 | regulation of reactive oxygen species metabolic process | biological process | GO:2000377 | 147 | 23 | 16441 | 1675 |
CLCN3,PINK1,FBLN5,RHOA,AKT1,FOXM1,TP53,PDK3,HDAC6,PDGFB,GSTP1,ARF4,PLIN5,STK17A,IER3,BMP7,PRCP,TFAP2A,GLA,F2RL1,SYK,CYP1B1,XDH |
| 2.454e-02 | -3.71 | response to glucocorticoid | biological process | GO:0051384 | 147 | 23 | 16441 | 1675 |
ANXA3,CASP3,RHOA,NR3C1,PTPRU,CALM1,CASP9,CALM3,FOS,SDC1,FAS,SOCS3,FECH,TFAP4,CCND1,MDK,CALM2,CTSV,FOSB,BAX,GOT1,IGFBP2,KLF9 |
| 2.454e-02 | -3.71 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032434 | 147 | 23 | 16441 | 1675 |
PLK1,DLGAP5,AKT1,DNAJB2,GCLC,PBK,CDC20,NUB1,PRICKLE1,PSMD10,TRIB2,RNF19B,BCAP31,RAD23A,PTEN,PLK2,AURKA,DAB2IP,BUB1,CENPE,UBE2C,ESPL1,SOCS5 |
| 2.454e-02 | -3.71 | regulation of cell projection assembly | biological process | GO:0060491 | 147 | 23 | 16441 | 1675 |
SSH3,SSH1,TBC1D1,TGFBR1,PRKCQ,NCKAP1,MNS1,EPS8L2,DPYSL3,ARHGAP24,CORO1C,FAM110C,ATP8B1,KLF5,TACSTD2,ESPN,PLD1,ARPC2,ARF6,F2RL1,RAP1GAP,COBL,ADAMTS16 |
| 2.459e-02 | -3.71 | Fz | pfam domains | PF01392 | 23 | 6 | 16629 | 1696 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6 |
| 2.460e-02 | -3.71 | LABBE_TGFB1_TARGETS_DN | MSigDB lists | LABBE_TGFB1_TARGETS_DN | 103 | 17 | 17758 | 1761 |
CASP3,SEMA6B,PLSCR1,PLAUR,GCLC,TAP1,GDF15,DHRS3,ALCAM,FGF19,ELF3,PLCG1,AP1M2,MDM1,PGRMC1,BUB1,ACSL4 |
| 2.460e-02 | -3.71 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | 103 | 17 | 17758 | 1761 |
ANXA3,LZTFL1,PPP4R4,NUAK1,STAT4,LOXL2,DHRS3,FBLN1,NFIB,SYTL2,FZD7,PRKAG2,GPRC5B,PLOD2,TLE1,EPB41L4B,LTBP2 |
| 2.462e-02 | -3.70 | trachea | COSMIC cancer mutations | trachea | 12 | 4 | 17775 | 1757 |
ERBB2,PTEN,PIK3CA,TP53 |
| 2.462e-02 | -3.70 | extraadrenal | COSMIC cancer mutations | extraadrenal | 12 | 4 | 17775 | 1757 |
GNAS,CDKN2C,PTEN,RET |
| 2.462e-02 | -3.70 | GH-PRL | COSMIC cancer mutations | GH-PRL | 12 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 2.462e-02 | -3.70 | pituitary-adenoma-GH-PRL | COSMIC cancer mutations | pituitary-adenoma-GH-PRL | 12 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 2.463e-02 | -3.70 | human chr6p21 | chromosome location | human chr6p21 | 32 | 6 | 26250 | 1887 |
RUNX2,HMGA1,ITPR3,ETV7,STK38,MDFI |
| 2.464e-02 | -3.70 | intracellular transport | biological process | GO:0046907 | 1375 | 162 | 16441 | 1675 |
LAMP1,EXPH5,ACACB,CPT2,SLC25A13,TAP1,TGOLN2,SYTL4,HDAC6,SLC8B1,ERP29,ZFYVE16,RAB15,AP1M2,STEAP2,SNX16,RAB20,RP2,PIK3CD,TINAGL1,CTTN,TRAM1,MYRIP,S100A13,RASGRP1,ARFRP1,KIF13A,ICMT,MCFD2,OPTN,WIPI1,GNPTAB,ATP7B,TRAF3IP1,PRKAA2,GGA1,PEX6,RAB23,RAB6A,SLC1A3,FAM21C,LMNA,ATG4A,DOPEY2,SNX18,GATA2,ATP5H,RPL39,KIF13B,RANBP1,SORL1,PIKFYVE,SYTL3,NUP85,PPP6R1,RIMS2,KDELR1,TRAK2,PMPCB,ERO1A,STRADB,NPC2,STX3,GNAS,AP1AR,SCARB2,PRKAG2,TIMM8A,NFKBIA,ITPR1,ZDHHC7,CTSA,LTBP2,NDE1,HOOK1,JAK3,NRBP1,TOB1,NUP58,EHD1,MTM1,SLC25A24,CCDC109B,UPF3B,TP53,FTH1,BCL2L1,EMP2,BCAP31,SYTL2,APPBP2,ZFYVE9,TTC21B,KIF14,ZDHHC12,PLCG2,ZDHHC23,BCL6,RPN2,IFIT1,RAB27B,LMAN1,F2R,CHP1,ATG4D,PPIF,SEC23A,SEC61B,AKT1,COG2,HTATIP2,KIF1C,RAB38,ATP1B1,ITPR3,DAG1,ATP10D,TAPBP,DDOST,PEX2,SPTBN5,RGS14,SLC25A30,ABCA1,SORT1,CD63,ATP9A,ARL4C,PDIA3,CTSZ,AIP,VPS26A,HMGXB4,ZDHHC21,M6PR,KIF5B,MLPH,ADORA1,CTSC,KLC3,BAX,ABCD1,SYK,MYO5A,HES1,RAB3B,LCA5,ZC3H11A,MRS2,PIK3R1,PRICKLE1,COL7A1,BBS2,RPL12,SERPINA1,NR4A3,ARRB1,MCUR1,SPCS3,ARSB,NDFIP1,ABCG1 |
| 2.465e-02 | -3.70 | phagocytosis | biological process | GO:0006909 | 163 | 25 | 16441 | 1675 |
ANXA3,CLCN3,PIK3R1,EIF2AK1,ITPR2,NCKAP1,YES1,ITPR3,MERTK,PLCG1,ADORA1,GATA2,ELMO2,AXL,LIMK1,CORO1C,PLCG2,ITPR1,PIK3CA,RAB20,ITGAV,ARPC2,SYK,ABCA1,XKR8 |
| 2.468e-02 | -3.70 | single organism reproductive process | biological process | GO:0044702 | 1037 | 125 | 16441 | 1675 |
CCNI,LGR4,GRHL2,EPAS1,AK7,GNPDA1,ST14,CAST,PTTG1,HEXB,TESK2,ERBB2,TDRKH,BCL2L1,CCNB1,PRKACA,PDGFB,SDC1,EMP2,MNS1,BCAP31,CCND1,CYP1A1,HSF2,RPS6KA2,LRRC6,PAQR5,PLK4,BCL6,AKR1B1,ACSL4,TIPARP,GPX4,SIRT1,SMARCA2,SPEF2,CELSR2,AKT1,FZD4,TFAP2C,IGSF8,PYGO1,CCNF,IDH1,CDK1,SOCS3,HS6ST1,HOXA9,AXL,OVOL1,GAB1,E2F8,NR2C2,PCSK5,GRN,COL9A3,NKX3-1,CDKN1C,SERPINE2,CENPI,CIT,SOX9,ETV5,MTL5,TGFBR1,SBF1,FBLN1,ETS1,MERTK,LMNA,SIX4,SGPL1,B4GALNT1,E2F7,DAZAP1,ITGA3,ITGB8,IGF1R,CYR61,CDK16,GATA2,SPIN4,PTEN,CST3,TOX2,UBE2J1,CD9,BAX,TMBIM6,CRTAP,MDFI,PAQR7,CYP26B1,REC8,ADAMTS2,HES1,TESK1,ASPM,EIF5A2,UBE2A,DIAPH2,ATP8B3,FNDC3A,BBS2,PRDX4,PITX2,NCOA3,FGFR2,PVRL2,PLPP3,UTP14C,CTSV,SPINT2,SFMBT1,ARRB1,HOXB13,FZD5,OSR1,SOX8,ZMIZ1,HOOK1,RARG,APOL2,AHR,EGLN1 |
| 2.468e-02 | -3.70 | Ras_GEF_dom | interpro domains | IPR023578 | 30 | 7 | 18293 | 1814 |
BCAR3,RASGRF1,RASGEF1A,RALGPS2,RAPGEF2,RASGRP1,RASGRP2 |
| 2.468e-02 | -3.70 | RASGEF_cat_dom | interpro domains | IPR001895 | 30 | 7 | 18293 | 1814 |
BCAR3,RASGRF1,RALGPS2,RASGEF1A,RAPGEF2,RASGRP1,RASGRP2 |
| 2.468e-02 | -3.70 | GNF2_PRDX2 | MSigDB lists | GNF2_PRDX2 | 30 | 7 | 17758 | 1761 |
GCLM,CA2,MINPP1,HEBP1,SPTB,AMMECR1,BLVRB |
| 2.468e-02 | -3.70 | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | MSigDB lists | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | 30 | 7 | 17758 | 1761 |
MAPKAPK2,MAPK11,RPS6KA2,DUSP4,ELK1,FOS,RPS6KA1 |
| 2.468e-02 | -3.70 | MODULE_221 | MSigDB lists | MODULE_221 | 30 | 7 | 17758 | 1761 |
ACOX2,ALDH2,ALDH6A1,ACADSB,CPT2,ALDH3A2,BLVRB |
| 2.468e-02 | -3.70 | VIRAL_INFECTIOUS_CYCLE | MSigDB lists | VIRAL_INFECTIOUS_CYCLE | 30 | 7 | 17758 | 1761 |
TOP2A,MDFIC,WWP1,TNIP1,APOBEC3G,ITCH,WWP2 |
| 2.468e-02 | -3.70 | REACTOME_HS_GAG_BIOSYNTHESIS | MSigDB lists | REACTOME_HS_GAG_BIOSYNTHESIS | 30 | 7 | 17758 | 1761 |
HS6ST1,HS3ST3B1,HSPG2,SDC1,NDST3,SDC4,GLCE |
| 2.468e-02 | -3.70 | PID_RAS_PATHWAY | MSigDB lists | PID_RAS_PATHWAY | 30 | 7 | 17758 | 1761 |
RASGRF1,DAB2IP,LGALS3,RASA2,RASGRP1,RASA1,RASGRP2 |
| 2.468e-02 | -3.70 | PID_EPHRINB_REV_PATHWAY | MSigDB lists | PID_EPHRINB_REV_PATHWAY | 30 | 7 | 17758 | 1761 |
YES1,EPHB4,TIAM1,RGS3,EFNB1,PIK3R1,PIK3CA |
| 2.468e-02 | -3.70 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | 30 | 7 | 17758 | 1761 |
MTM1,PIK3C2B,PIK3CD,PTEN,PIK3R1,INPP4B,PIK3CA |
| 2.468e-02 | -3.70 | GNF2_EGFR | MSigDB lists | GNF2_EGFR | 30 | 7 | 17758 | 1761 |
GDF15,TIMP2,CAPN6,SDC1,ALPP,MAFF,TFAP2A |
| 2.468e-02 | -3.70 | PID_RETINOIC_ACID_PATHWAY | MSigDB lists | PID_RETINOIC_ACID_PATHWAY | 30 | 7 | 17758 | 1761 |
HDAC1,NCOA3,AKT1,PRKACA,CDK1,RARG,NCOA2 |
| 2.468e-02 | -3.70 | alpha-amino acid metabolic process | biological process | GO:1901605 | 253 | 36 | 16441 | 1675 |
PLA2G4A,GCLM,ALDH6A1,AASS,CRYM,HAL,SLC1A3,OAT,SPR,SRR,SERINC2,ALDH7A1,AHCY,GOT1,EGLN3,GAD1,CRTAP,MCCC2,FAH,CTH,GFPT1,PRODH,SHMT1,PLSCR1,GCLC,ERO1A,GGH,ICMT,AMDHD1,PRDX4,ALDH5A1,ABHD12,P4HA2,SLC27A1,OCLN,EGLN1 |
| 2.471e-02 | -3.70 | REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_MAP_KINASE_ACTIVITY | 65 | 12 | 17758 | 1761 |
SPRED1,RGS3,MADD,MAP3K9,ERBB2,MDFIC,MAP3K5,TRIB2,PKN1,MAP3K6,HIPK3,MDFI |
| 2.471e-02 | -3.70 | RIGGINS_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_UP | 65 | 12 | 17758 | 1761 |
ALDH3B1,PRODH,ARMCX3,SERPINA1,CELSR2,RGS3,LRP4,RET,CTSA,ASB13,ARMCX6,PTGES |
| 2.482e-02 | -3.70 | V$VDR_Q3 | MSigDB lists | V$VDR_Q3 | 209 | 30 | 17758 | 1761 |
BCAM,SLC2A4,BMF,HOXB7,PPM1J,GGA1,FOXJ2,THRA,TSC22D3,FURIN,FOS,SH3KBP1,PRX,MECOM,CXXC4,TIMP3,RALGPS2,C19orf66,FGFR2,PTK7,TMEM30A,LMO4,BHLHE41,RRBP1,NR4A3,RFX5,PRIMA1,NCAM1,NRGN,RARG |
| 2.482e-02 | -3.70 | CATION_BINDING | MSigDB lists | CATION_BINDING | 209 | 30 | 17758 | 1761 |
GCA,KCNIP3,MCTP1,REPS2,SLC25A13,S100A4,CALM1,TP53,CDA,CALM3,NUCB2,HPCAL4,NCS1,CDK5R1,CALM2,MMP15,FECH,RCN1,CA2,STIM1,CABP1,ATP7B,MMP17,PIM1,LTA4H,S100A13,APOBEC3G,RASGRP1,ERAP2,KLF7 |
| 2.483e-02 | -3.70 | CATTTCA,MIR-203 | MSigDB lists | CATTTCA,MIR-203 | 277 | 38 | 17758 | 1761 |
LASP1,CPEB4,NUAK1,XYLT1,C5orf30,NKRF,ITPR2,MORF4L2,KCTD9,AKIRIN1,FAM46A,SGK3,PRKG1,VAT1,LIMCH1,PDE4D,CITED2,SLC12A2,LAMP2,STEAP1,SP4,SOX13,SOCS3,GABARAPL1,IRS2,ETS2,SLC4A4,KLF12,PRPS2,NR4A3,OVOL1,PCDH19,CAB39,ZMIZ1,GLCCI1,AHR,EGLN1,NR2C2 |
| 2.483e-02 | -3.70 | HAD-like_dom | interpro domains | IPR023214 | 80 | 14 | 18293 | 1814 |
CMAS,ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,CTDSPL,ATP8B1,ATP8B3,LPIN3,ATP10D,CTDSP2,ATP2B1,ATP13A2 |
| 2.488e-02 | -3.69 | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_II | 7 | 3 | 17775 | 1757 |
CDKN2C,IDH1,PTEN |
| 2.488e-02 | -3.69 | stomach-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | stomach-carcinoma-mixed_adenosquamous_carcinoma | 7 | 3 | 17775 | 1757 |
ERBB2,PTEN,TP53 |
| 2.488e-02 | -3.69 | temporooccipital | COSMIC cancer mutations | temporooccipital | 7 | 3 | 17775 | 1757 |
CDKN2C,IDH1,TP53 |
| 2.488e-02 | -3.69 | peritoneum-carcinoma-peritoneal_serous_surface_carcinoma | COSMIC cancer mutations | peritoneum-carcinoma-peritoneal_serous_surface_carcinoma | 7 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 2.488e-02 | -3.69 | neuronal_tumour | COSMIC cancer mutations | neuronal_tumour | 7 | 3 | 17775 | 1757 |
ERBB2,AKT1,PIK3CA |
| 2.488e-02 | -3.69 | peritoneal_serous_surface_carcinoma | COSMIC cancer mutations | peritoneal_serous_surface_carcinoma | 7 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 2.488e-02 | -3.69 | central_nervous_system-occipital_lobe-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-occipital_lobe-glioma-astrocytoma_Grade_II | 7 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 2.488e-02 | -3.69 | skin-neck-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-neck-other-seborrhoeic_keratosis | 7 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 2.488e-02 | -3.69 | soft_tissue-blood_vessel-haemangioblastoma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioblastoma | 7 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 2.488e-02 | -3.69 | bone-vertebrae-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-vertebrae-chondrosarcoma-dedifferentiated | 7 | 3 | 17775 | 1757 |
IDH1,PIK3CA,TP53 |
| 2.488e-02 | -3.69 | haemangioblastoma | COSMIC cancer mutations | haemangioblastoma | 7 | 3 | 17775 | 1757 |
IDH1,PTEN,TP53 |
| 2.488e-02 | -3.69 | bone-chest_wall-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chest_wall-chondrosarcoma-dedifferentiated | 7 | 3 | 17775 | 1757 |
IDH1,PIK3CA,TP53 |
| 2.488e-02 | -3.69 | central_nervous_system-temporal_lobe-neuronal_tumour | COSMIC cancer mutations | central_nervous_system-temporal_lobe-neuronal_tumour | 7 | 3 | 17775 | 1757 |
ERBB2,AKT1,PIK3CA |
| 2.488e-02 | -3.69 | skin-shoulder-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-shoulder-other-seborrhoeic_keratosis | 7 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 2.488e-02 | -3.69 | lung-carcinoma-carcinosarcoma | COSMIC cancer mutations | lung-carcinoma-carcinosarcoma | 7 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 2.488e-02 | -3.69 | skin-chest-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-chest-other-seborrhoeic_keratosis | 7 | 3 | 17775 | 1757 |
AKT1,PTEN,PIK3CA |
| 2.488e-02 | -3.69 | bone-radius-chondrosarcoma-conventional | COSMIC cancer mutations | bone-radius-chondrosarcoma-conventional | 7 | 3 | 17775 | 1757 |
IDH1,PIK3CA,TP53 |
| 2.489e-02 | -3.69 | Peptidase_M1 | interpro domains | IPR001930 | 12 | 4 | 18293 | 1814 |
ERAP1,RNPEP,LTA4H,ERAP2 |
| 2.489e-02 | -3.69 | WWE-dom | interpro domains | IPR004170 | 12 | 4 | 18293 | 1814 |
PARP12,TIPARP,RNF146,DTX4 |
| 2.489e-02 | -3.69 | POS_RESPONSE_TO_HISTAMINE_UP | MSigDB lists | POS_RESPONSE_TO_HISTAMINE_UP | 12 | 4 | 17758 | 1761 |
HMG20B,FBLN5,UPF3B,FRYL |
| 2.489e-02 | -3.69 | RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 12 | 4 | 17758 | 1761 |
ARHGEF3,ARHGEF11,TIAM1,FARP2 |
| 2.489e-02 | -3.69 | ARYLSULFATASE_ACTIVITY | MSigDB lists | ARYLSULFATASE_ACTIVITY | 12 | 4 | 17758 | 1761 |
ARSB,ARSG,ARSK,SULF2 |
| 2.489e-02 | -3.69 | BIOCARTA_TRKA_PATHWAY | MSigDB lists | BIOCARTA_TRKA_PATHWAY | 12 | 4 | 17758 | 1761 |
PLCG1,AKT1,PIK3R1,PIK3CA |
| 2.489e-02 | -3.69 | TAGHAVI_NEOPLASTIC_TRANSFORMATION | MSigDB lists | TAGHAVI_NEOPLASTIC_TRANSFORMATION | 12 | 4 | 17758 | 1761 |
MAP3K3,GRHL1,PDGFB,FOSB |
| 2.489e-02 | -3.69 | NEGATIVE_REGULATION_OF_PHOSPHORYLATION | MSigDB lists | NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 12 | 4 | 17758 | 1761 |
CDKN2C,CDKN1B,NF2,CDKN2D |
| 2.489e-02 | -3.69 | PROTEIN_TARGETING_TO_MEMBRANE | MSigDB lists | PROTEIN_TARGETING_TO_MEMBRANE | 12 | 4 | 17758 | 1761 |
ICMT,TRAM1,ATG4D,ATG4A |
| 2.489e-02 | -3.69 | CDC42_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | CDC42_PROTEIN_SIGNAL_TRANSDUCTION | 12 | 4 | 17758 | 1761 |
FGD6,ABCA1,RALBP1,FGD1 |
| 2.489e-02 | -3.69 | MODULE_396 | MSigDB lists | MODULE_396 | 12 | 4 | 17758 | 1761 |
GABRG2,CLCN3,SLC12A2,FXYD3 |
| 2.489e-02 | -3.69 | GSE3982_CTRL_VS_LPS_48H_DC_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_UP | 184 | 27 | 17758 | 1761 |
DLGAP5,CHCHD7,ATP9A,PBK,CORO2A,CTDSPL,ARL4C,GLO1,RAB38,MERTK,HDAC9,CCDC92,DNAJC10,FUT2,CTSC,CORO1C,PAPSS1,OPN3,SORL1,ALDH7A1,AHCY,PER3,FAR2,CLIP2,SLC16A5,CPPED1,RBMS2 |
| 2.489e-02 | -3.69 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_UP | 184 | 27 | 17758 | 1761 |
NFKBIE,DEPDC1,EPAS1,GCLC,ARL4C,NFE2L1,CR2,CAMK1D,BARD1,GLT8D2,TSPAN7,SH2D4A,TEAD3,SOCS3,TFAP4,RASSF8,TAPBP,TIMP3,STIM1,LIMK1,PHLPP2,LRIG1,DIXDC1,RARG,NRBP1,ATP2B1,PCSK5 |
| 2.489e-02 | -3.69 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 184 | 27 | 17758 | 1761 |
CCNE2,NUDT6,SHMT1,FRMD6,CENPI,CCDC34,GLO1,BLVRA,XRCC6BP1,RNPEP,LEPR,PRDX4,LRRC42,SLCO4A1,WIPI1,ANKRD6,PRCP,SIVA1,BDH1,CEP78,PGRMC1,MDH1,LRP11,APOL2,CRTAP,STARD3NL,CKS2 |
| 2.489e-02 | -3.69 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | 184 | 27 | 17758 | 1761 |
MBP,FRMD4A,GNPDA1,MBNL3,TTC7A,MRAS,PDK3,PKN1,ICMT,LBR,TMEM63A,CCDC92,MARCH8,FAM111A,IGF1R,PRCP,CDCA7L,CEP78,PCYOX1,PGM2L1,C10orf54,SLC39A10,NDUFA12,CNPY3,NUP85,CRTAP,CD33 |
| 2.491e-02 | -3.69 | TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | 111 | 18 | 17758 | 1761 |
SIRT1,UGT8,XYLT1,MGAT4B,GALNT7,POMGNT1,B4GALT4,B4GALNT1,GALNT3,TYMP,B3GALNT1,FUT2,MGAT4A,A4GALT,FUT8,FUT1,ST3GAL1,GCNT1 |
| 2.492e-02 | -3.69 | TPR | prosite domains | PS50005 | 106 | 18 | 11866 | 1235 |
TTC8,TMTC1,LONRF3,CEP70,DNAJC3,TTC7A,EMC2,GPSM2,IFIT3,NPHP3,AIP,APPBP2,TTC21B,P4HA2,KLC3,CABIN1,IFIT1,TANC2 |
| 2.492e-02 | -3.69 | PML (promyelocytic leukemia) | protein interactions | 5371 | 193 | 30 | 16036 | 1726 |
SIRT1,TGIF1,RUNX2,PLSCR1,NR3C1,NR4A1,THRA,SYNE2,HDAC11,TP53,RUNX3,TGFBR1,HDAC6,FOS,CDK1,ZFYVE9,LMNA,FAS,IER3,PLCG1,SP100,JAK1,TRIM69,GATA2,BCL6,AURKA,HDAC1,MAPK11,NR2C1,NCOA2 |
| 2.493e-02 | -3.69 | GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB | MSigDB lists | GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB | 143 | 22 | 17758 | 1761 |
SORBS1,PPP1R2,CAPN6,ITCH,SEPT6,ATP2C2,CTDSPL,SAT1,CACNA2D2,NRG2,PRKCQ,NKRF,IL27RA,SPTB,SNTA1,NCOA3,CA2,SP100,PLOD2,TLE1,IRF7,SNX10 |
| 2.493e-02 | -3.69 | Acetaminophen Metabolism Pathway | SMPDB pathways | SMP00640 | 28 | 8 | 978 | 131 |
ABCB1,ABCG2,DNAJB11,ERP29,GSTP1,PDIA6,PDIA4,ABCC1 |
| 2.495e-02 | -3.69 | Fc receptor mediated stimulatory signaling pathway | biological process | GO:0002431 | 78 | 14 | 16441 | 1675 |
PLCG1,ELMO2,LIMK1,ITPR1,PIK3R1,PLCG2,PIK3CA,NR4A3,ITPR2,NCKAP1,YES1,ITPR3,ARPC2,SYK |
| 2.504e-02 | -3.69 | V$MEF2_03 | MSigDB lists | V$MEF2_03 | 226 | 32 | 17758 | 1761 |
SLC2A4,CPEB4,HOXB7,NDRG2,FAM81A,PPP2R3A,ZNF385B,HDAC9,SCML1,FOXP2,OPN3,NEK2,AKR1B1,TWIST1,PHKA2,ARMCX6,CRTAP,C9orf9,TRAK2,SMARCA2,RASGRF1,TIMP2,NR4A1,RGAG1,STRADB,FOS,ZFAND5,NFIB,ITGA7,RAP2C,SIPA1L1,AMMECR1 |
| 2.504e-02 | -3.69 | V$AP2ALPHA_01 | MSigDB lists | V$AP2ALPHA_01 | 226 | 32 | 17758 | 1761 |
IER5L,SCN5A,GRHL2,THRA,SOX9,PKN1,PDGFB,DDR1,TFAP4,APLP2,RNF220,ARTN,ZNRF2,ATP5H,LMO4,LHX6,TRPC1,NOTCH3,ETV4,DGKG,NR3C1,CBX6,RGAG1,NFIB,MAP3K6,SP4,CD83,PITX2,KLF12,RARG,NR2C2,JARID2 |
| 2.508e-02 | -3.69 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | 135 | 21 | 17758 | 1761 |
FADS2,SORT1,ALDH6A1,PQLC3,ADCK3,NFE2L1,SEPP1,IDH1,ERP29,LTBP3,TMCC3,BCAR3,SCARB2,AGPAT2,GPRC5B,EFR3A,PCYOX1,AOX1,FAM102A,DAB2IP,ATP1B3 |
| 2.508e-02 | -3.69 | RB_P107_DN.V1_UP | MSigDB lists | RB_P107_DN.V1_UP | 135 | 21 | 17758 | 1761 |
CCNE2,COL6A2,PCOLCE,FBLN5,CDKN1C,S100A4,BLVRB,CCNF,H2AFV,BEX2,SRPX2,LGALS3BP,H1FX,PRDX4,PRIM1,CA2,SIVA1,COL6A1,TUBG1,E2F8,COL16A1 |
| 2.508e-02 | -3.69 | beta-catenin binding | molecular function | GO:0008013 | 71 | 13 | 16491 | 1673 |
CTNNBIP1,PTPRJ,CDH1,NF2,PTPRU,BCL9,DACT1,AMER1,SOX9,TCF7,HDAC6,SHROOM2,APC2 |
| 2.509e-02 | -3.69 | PI3K_Ras-bd_dom | interpro domains | IPR000341 | 7 | 3 | 18293 | 1814 |
PIK3C2B,PIK3CD,PIK3CA |
| 2.509e-02 | -3.69 | GS_dom | interpro domains | IPR003605 | 7 | 3 | 18293 | 1814 |
TGFBR1,ACVR1C,ACVRL1 |
| 2.509e-02 | -3.69 | Anoct_dimer | interpro domains | IPR032394 | 7 | 3 | 18293 | 1814 |
ANO4,ANO1,ANO6 |
| 2.509e-02 | -3.69 | Furin-like_Cys-rich_dom | interpro domains | IPR006211 | 7 | 3 | 18293 | 1814 |
ERBB2,ERBB3,IGF1R |
| 2.509e-02 | -3.69 | PD_growth_factor_CS | interpro domains | IPR023581 | 7 | 3 | 18293 | 1814 |
PDGFA,PGF,PDGFB |
| 2.509e-02 | -3.69 | GoLoco_motif | interpro domains | IPR003109 | 7 | 3 | 18293 | 1814 |
GPSM2,RGS14,RAP1GAP |
| 2.509e-02 | -3.69 | Acyl-CoA-binding_protein | interpro domains | IPR000582 | 7 | 3 | 18293 | 1814 |
ACBD5,ECI2,DBI |
| 2.509e-02 | -3.69 | E-NPP | interpro domains | IPR024873 | 7 | 3 | 18293 | 1814 |
ENPP4,ENPP1,ENPP5 |
| 2.509e-02 | -3.69 | Glyco_trans_14 | interpro domains | IPR003406 | 7 | 3 | 18293 | 1814 |
XYLT2,XYLT1,GCNT1 |
| 2.509e-02 | -3.69 | GPCR_kinase | interpro domains | IPR000239 | 7 | 3 | 18293 | 1814 |
GRK6,ADRBK1,ADRBK2 |
| 2.509e-02 | -3.69 | Rcpt_L-dom | interpro domains | IPR000494 | 7 | 3 | 18293 | 1814 |
ERBB2,ERBB3,IGF1R |
| 2.509e-02 | -3.69 | Hematopoietin_rcpt_Gp130_CS | interpro domains | IPR003529 | 7 | 3 | 18293 | 1814 |
LEPR,LIFR,IL6ST |
| 2.509e-02 | -3.69 | IKEDA_MIR1_TARGETS_DN | MSigDB lists | IKEDA_MIR1_TARGETS_DN | 7 | 3 | 17758 | 1761 |
CLCN3,STK39,MMD |
| 2.509e-02 | -3.69 | TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP | MSigDB lists | TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP | 7 | 3 | 17758 | 1761 |
SDC1,FGFR2,MYBL2 |
| 2.509e-02 | -3.69 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | 7 | 3 | 17758 | 1761 |
PIK3CA,MECOM,BCL6 |
| 2.509e-02 | -3.69 | ST_PAC1_RECEPTOR_PATHWAY | MSigDB lists | ST_PAC1_RECEPTOR_PATHWAY | 7 | 3 | 17758 | 1761 |
ASAH1,ITPKA,DAG1 |
| 2.509e-02 | -3.69 | INGRAM_SHH_TARGETS | MSigDB lists | INGRAM_SHH_TARGETS | 7 | 3 | 17758 | 1761 |
LASP1,NR4A1,TSC22D3 |
| 2.509e-02 | -3.69 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | MSigDB lists | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | 7 | 3 | 17758 | 1761 |
PHLPP1,AKT1,PTEN |
| 2.513e-02 | -3.68 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | 417 | 54 | 17758 | 1761 |
ETV5,CTDSPL,PPFIBP2,NDC80,ABCG2,TESK2,CALM3,PBX3,NUF2,NENF,SLC25A36,CALM2,APLP2,SESN3,HSF2,MLPH,KIF14,SIVA1,SRR,FUT1,SELK,PIK3CD,CTTN,CDKN2D,NEB,GPR161,SEPHS1,THRB,DOCK4,CD55,IFITM3,GUSB,RAPGEF2,SAT1,CALM1,FBXO9,SP4,KLHL2,PTPRF,HS6ST1,CDKN2AIPNL,KLF12,ETS2,GDE1,KCNK1,PLK2,MMP17,TMC5,HS3ST3B1,ATP1B3,GDF11,JAK3,NR3C2,SNPH |
| 2.519e-02 | -3.68 | Pancreatic cancer | KEGG pathways | ko05212 | 66 | 13 | 6908 | 758 |
CCND1,AKT1,JAK1,RALBP1,PIK3R1,CASP9,TP53,PIK3CA,ERBB2,TGFBR1,PLD1,PIK3CD,BCL2L1 |
| 2.519e-02 | -3.68 | Long-term potentiation | KEGG pathways | ko04720 | 66 | 13 | 6908 | 758 |
CALM2,RPS6KA2,RPS6KA1,ITPR1,CALM1,GRIN1,CALM3,GRIN2D,ITPR2,ITPR3,PLCB2,PRKACA,GRM5 |
| 2.519e-02 | -3.68 | Long-term potentiation | KEGG pathways | hsa04720 | 66 | 13 | 6908 | 758 |
CALM2,RPS6KA2,RPS6KA1,ITPR1,CALM1,GRIN1,CALM3,GRIN2D,ITPR2,ITPR3,PLCB2,PRKACA,GRM5 |
| 2.519e-02 | -3.68 | Pancreatic cancer | KEGG pathways | hsa05212 | 66 | 13 | 6908 | 758 |
CCND1,AKT1,JAK1,RALBP1,PIK3R1,CASP9,TP53,PIK3CA,ERBB2,TGFBR1,PLD1,PIK3CD,BCL2L1 |
| 2.523e-02 | -3.68 | MODULE_532 | MSigDB lists | MODULE_532 | 373 | 49 | 17758 | 1761 |
LMTK3,FAM169A,AASS,MRPS15,TP53,SLC25A27,C6orf106,ISYNA1,NANS,IL18R1,CMTM6,C9orf69,CYP1A1,RNF220,CDK16,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,CNOT6L,CITED2,FAIM,ATG4D,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,TMEM144,SLC11A2,PIF1,SAV1,FOS,MYL12A,BSDC1,KDM4D,AMZ2,NEIL1,CSF1,PLEKHG1,S100A5,FGD6,MAL2,GEM,TMEM120A,RRAGD |
| 2.526e-02 | -3.68 | kinesin binding | molecular function | GO:0019894 | 36 | 8 | 16491 | 1673 |
AP1AR,PIFO,SYBU,FAM83D,KLC3,SPTBN5,ARPC2,MAPK8IP1 |
| 2.527e-02 | -3.68 | FKBP9 (FK506 binding protein 9) | protein interactions | 11328 | 22 | 6 | 16036 | 1726 |
EZR,STK39,H2AFV,NUBP1,RAD23A,EHD1 |
| 2.527e-02 | -3.68 | SCNN1B (sodium channel, non voltage gated 1 beta subunit) | protein interactions | 6338 | 22 | 6 | 16036 | 1726 |
SGK1,SCNN1A,AP1M2,TSC22D3,ITCH,WWP2 |
| 2.527e-02 | -3.68 | NFE2 (nuclear factor, erythroid 2) | protein interactions | 4778 | 22 | 6 | 16036 | 1726 |
NFE2L3,WWP1,TXN,MAFF,ITCH,ELF5 |
| 2.527e-02 | -3.68 | TRNT1 (tRNA nucleotidyl transferase, CCA-adding, 1) | protein interactions | 51095 | 22 | 6 | 16036 | 1726 |
EZR,CTSA,SH3BP1,H2AFV,GNPDA1,RAD23A |
| 2.527e-02 | -3.68 | CENPH (centromere protein H) | protein interactions | 64946 | 22 | 6 | 16036 | 1726 |
NUF2,CENPA,CENPN,CENPI,RASSF7,NDC80 |
| 2.527e-02 | -3.68 | EGF (epidermal growth factor) | protein interactions | 1950 | 22 | 6 | 16036 | 1726 |
MAPKAPK2,ERBB2,NRG1,ERBB3,ADRBK1,LMNA |
| 2.527e-02 | -3.68 | KCTD3 (potassium channel tetramerization domain containing 3) | protein interactions | 51133 | 22 | 6 | 16036 | 1726 |
EPN3,ARRB1,HSPB1,DNAJB2,SH3KBP1,SCRN2 |
| 2.532e-02 | -3.68 | vif (p23) | protein interactions | 155459 | 320 | 46 | 16036 | 1726 |
PRKAA2,RUNX2,PSME2,DNAJB2,ITGA6,XYLT1,TP53,PSMD10,APOBEC3H,PSME1,CCNB1,PRKACA,MNS1,ATG4A,APOBEC3B,PSMD1,ADD3,GATA2,SLC16A6,IL31RA,ULBP2,APOBEC3G,SCN3A,ATG4D,PSMB4,APOBEC3D,IFITM3,ITCH,PCBP3,SAT1,LITAF,CR2,PRKAR2B,MAML2,RUNX3,IFIT3,CDK1,PSMA4,RND3,ISM1,CSF1,UACA,TLE1,NR4A2,MAP3K5,EGLN1 |
| 2.534e-02 | -3.68 | ATF2_S_UP.V1_DN | MSigDB lists | ATF2_S_UP.V1_DN | 176 | 26 | 17758 | 1761 |
SORBS1,ENO2,SLC39A8,GALNT12,AK4,KCTD12,COL7A1,ROR1,SLC1A3,VASH1,KBTBD11,FOS,NFIB,LTBP3,GABRD,PDLIM3,PTER,ITPR1,SPINT2,DAPK1,CLMN,IGFBP2,CBX7,COL16A1,NXT2,CYP1B1 |
| 2.534e-02 | -3.68 | KEGG_CALCIUM_SIGNALING_PATHWAY | MSigDB lists | KEGG_CALCIUM_SIGNALING_PATHWAY | 176 | 26 | 17758 | 1761 |
CALM1,GRIN1,ERBB2,CALM3,ITPR2,ITPR3,SLC25A5,PRKACA,GNA11,GRM5,EDNRA,GNAS,CALM2,PLCG1,SLC25A4,PLCG2,ITPR1,TRPC1,GRIN2D,CACNA1D,ERBB3,PHKA2,ITPKA,F2R,PLCB2,ATP2B1 |
| 2.537e-02 | -3.67 | response to drug | biological process | GO:0042493 | 415 | 55 | 16441 | 1675 |
PRKAA2,EMX1,CASP3,GCLM,NKX3-1,THRA,RET,ABCG2,TP53,GABRG2,COL18A1,ERBB2,SLC1A3,CCNB1,PDGFB,CCND1,SS18,CYP1A1,ADD3,ITGA3,CDH1,PTEN,DPYSL2,CYP2S1,CST3,FOSB,SRR,BAX,ABCA2,ATP8B1,CDH3,CDKN1B,IGFBP2,RPN2,ABCC1,TGIF1,TIMP2,RHOA,PARP4,AK4,GGH,PRKAR2B,FOS,POR,GPLD1,SOCS3,GNAS,FECH,MDK,BCAR3,ATP1A1,TMEM30A,ABCB1,CYP2U1,CBX7 |
| 2.539e-02 | -3.67 | GSE29618_MONOCYTE_VS_MDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DN | 201 | 29 | 17758 | 1761 |
BIN1,SMARCA2,SEPT6,PTTG1,ARL4C,NDRG2,IL13RA1,IL18,TRIB2,DHRS3,ALCAM,FAM46C,IL18R1,SLC9A7,PARM1,HDAC9,WEE1,BANK1,AXL,HOXA9,SPINT2,CST3,SH3BP4,HMGA1,LGMN,ARF6,TMEM14A,TOB1,CCDC88A |
| 2.545e-02 | -3.67 | sulfur compound biosynthetic process | biological process | GO:0044272 | 204 | 30 | 16441 | 1675 |
CHSY3,B3GALT6,OPLAH,SLC35D2,ACACB,B3GNT7,GCLM,B3GNT2,PAPSS2,GCLC,XYLT1,ELOVL3,MGST2,B4GALT4,DSE,GSTP1,CHPF,GLCE,HS6ST1,XYLT2,PAPSS1,GOT1,AHCY,ACSL4,HS3ST3B1,TECR,ST3GAL1,NDST3,ACOT7,CTH |
| 2.548e-02 | -3.67 | external side of plasma membrane | cellular component | GO:0009897 | 233 | 33 | 17570 | 1756 |
LAMP1,BCAM,SLC2A4,LGALS3,SERPINE2,ITGA6,SELL,CD274,PLPPR4,SDC1,ANO1,TMC1,SCNN1A,ITGA3,IL6ST,CD9,ECE1,C10orf54,NCAM1,CLCN3,CR2,CD40,ALCAM,FAS,CD83,CTSV,NRG1,EFNA5,ITGAV,L1CAM,ABCA1,ABCG1,CD33 |
| 2.554e-02 | -3.67 | nucleotide-activated protein kinase complex | cellular component | GO:0031588 | 12 | 4 | 17570 | 1756 |
PRKAA2,PRKAG2,PRKACA,NUAK1 |
| 2.562e-02 | -3.66 | dystroglycan complex | cellular component | GO:0016011 | 7 | 3 | 17570 | 1756 |
SGCE,SGCB,DAG1 |
| 2.563e-02 | -3.66 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 209 | 32 | 16036 | 1726 |
RPS6KA1,IQGAP1,RET,TP53,HDAC6,ETS1,TTYH3,IER3,FOXP2,RPS6KA2,ADRBK1,DAPK1,DUSP10,ADAM15,PTPRE,SYK,METAP2,HMMR,TGIF1,MBP,CASP9,SYNE2,PPARA,SCRIB,ELK1,DUSP4,MAPKAPK2,ATP1A1,RYK,ARRB1,NUP58,GAB1 |
| 2.564e-02 | -3.66 | REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | MSigDB lists | REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | 58 | 11 | 17758 | 1761 |
CASP3,RASGRF1,ARHGEF3,ARHGEF11,NGFRAP1,TIAM1,ARHGEF9,ARHGEF16,ABR,ARHGEF4,FGD1 |
| 2.564e-02 | -3.66 | REACTOME_INTERFERON_GAMMA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_GAMMA_SIGNALING | 58 | 11 | 17758 | 1761 |
HLA-B,JAK1,SP100,HLA-F,IRF2,IRF7,OAS3,HLA-C,NCAM1,HLA-A,SOCS3 |
| 2.564e-02 | -3.66 | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | MSigDB lists | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | 58 | 11 | 17758 | 1761 |
MAP3K3,CCND1,NCOA3,EPAS1,RPS6KA1,ARRB1,IRF7,NOTCH3,ZFAND5,CARD10,NR2C2 |
| 2.567e-02 | -3.66 | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | 37 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,IDH1,GNA11 |
| 2.567e-02 | -3.66 | salivary_gland-orbital-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-orbital-carcinoma-adenoid_cystic_carcinoma | 37 | 8 | 17775 | 1757 |
DIRAS3,RUNX2,FGFR2,MAP3K9,SEPP1,ALDH3A2,ABCA1,ESPL1 |
| 2.567e-02 | -3.66 | orbital | COSMIC cancer mutations | orbital | 37 | 8 | 17775 | 1757 |
DIRAS3,RUNX2,FGFR2,MAP3K9,SEPP1,ALDH3A2,ABCA1,ESPL1 |
| 2.567e-02 | -3.66 | haemangiopericytic | COSMIC cancer mutations | haemangiopericytic | 96 | 16 | 17775 | 1757 |
NF2,DEPDC1,ACVR1C,GGA1,TP53,ATP8B3,IDH1,IRS2,CDKN2C,PLCH1,SS18,TRANK1,SLC4A3,NDST3,MGAT5,EHD1 |
| 2.567e-02 | -3.66 | meninges-meningioma-haemangiopericytic | COSMIC cancer mutations | meninges-meningioma-haemangiopericytic | 96 | 16 | 17775 | 1757 |
NF2,DEPDC1,ACVR1C,GGA1,TP53,ATP8B3,IDH1,IRS2,CDKN2C,PLCH1,SS18,TRANK1,SLC4A3,NDST3,MGAT5,EHD1 |
| 2.568e-02 | -3.66 | response to transition metal nanoparticle | biological process | GO:1990267 | 124 | 20 | 16441 | 1675 |
GRIN1,ACO1,GGH,SLC11A2,LOXL2,CCNB1,ATP13A2,CCND1,FECH,NUCB1,CYP1A1,CA2,PTEN,ATP7B,BAX,TFAP2A,ARSB,LTA4H,S100A13,CYBRD1 |
| 2.572e-02 | -3.66 | MORI_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_UP | 88 | 15 | 17758 | 1761 |
ARHGEF3,ADD1,AIM1,SORL1,SELL,FAM102A,CR2,CNOT6L,RGS14,CD40,ETS1,CMTM6,ABCA1,CD83,B4GALNT1 |
| 2.572e-02 | -3.66 | SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 88 | 15 | 17758 | 1761 |
DIRAS3,ARAP3,RHOA,LIMK1,RALBP1,FGD6,MRAS,ARHGDIB,PLD1,ARF6,ABCA1,RASGRP1,ABR,FGD1,FARP2 |
| 2.572e-02 | -3.66 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | 88 | 15 | 17758 | 1761 |
AHRR,ENDOD1,SCARB2,SPEF2,ERLEC1,FAM46A,MACC1,TACC1,FBXO2,NTN4,EFNA5,TSPAN13,NPTXR,CPEB2,PARM1 |
| 2.573e-02 | -3.66 | RBM12 (RNA binding motif protein 12) | protein interactions | 10137 | 28 | 7 | 16036 | 1726 |
GAS2L1,BIN1,DAZAP1,PSMD1,CYP1A1,TBC1D4,GNE |
| 2.573e-02 | -3.66 | CAMK1 (calcium/calmodulin-dependent protein kinase I) | protein interactions | 8536 | 28 | 7 | 16036 | 1726 |
CDKN1B,CCND1,CAMK1D,HSPB1,CAMKK1,CALM1,HDAC9 |
| 2.573e-02 | -3.66 | GLMN (glomulin, FKBP associated protein) | protein interactions | 11146 | 28 | 7 | 16036 | 1726 |
ARRDC1,NRG1,RP2,SAV1,HSPB1,TMEM55B,TMEM173 |
| 2.573e-02 | -3.66 | KCNA5 (potassium channel, voltage gated shaker related subfamily A, member 5) | protein interactions | 3741 | 28 | 7 | 16036 | 1726 |
SNTA1,SIRT1,PRKCQ,ERBB2IP,FHL1,PTPRE,DLG1 |
| 2.578e-02 | -3.66 | ATGTTAA,MIR-302C | MSigDB lists | ATGTTAA,MIR-302C | 235 | 33 | 17758 | 1761 |
ZCCHC24,DCAF7,IL13RA1,NRP2,SIPA1L2,DAZAP1,ADD3,ANKRD12,PDE4D,PTPRE,BTBD3,MYT1,GAD1,SIRT1,PHF20L1,LCA5,FZD4,PPARA,VEZT,ABR,RHEB,SP4,NFIX,IRS2,FGFR2,CDK19,AMMECR1,FAM117A,ZMIZ1,LIFR,TOB1,CPEB2,NR3C2 |
| 2.584e-02 | -3.66 | mating | biological process | GO:0007618 | 36 | 8 | 16441 | 1675 |
THRB,GRN,APLP2,SERPINE2,PTEN,THRA,HEXB,GRIN1 |
| 2.584e-02 | -3.66 | positive regulation of leukocyte mediated cytotoxicity | biological process | GO:0001912 | 36 | 8 | 16441 | 1675 |
LAMP1,HLA-B,PVRL2,HLA-E,F2RL1,HLA-A,RASGRP1,SMAGP |
| 2.584e-02 | -3.66 | negative regulation of innate immune response | biological process | GO:0045824 | 36 | 8 | 16441 | 1675 |
HLA-B,NLRX1,HLA-E,NMI,NLRC5,TAP1,DUSP10,HLA-A |
| 2.584e-02 | -3.66 | regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000514 | 36 | 8 | 16441 | 1675 |
CD55,RIPK2,BCL6,PRKCQ,C10orf54,JAK3,CD83,SOCS5 |
| 2.586e-02 | -3.65 | negative regulation of phosphatase activity | biological process | GO:0010923 | 71 | 13 | 16441 | 1675 |
CAMSAP3,SPRED1,LMTK3,PPP4R4,SEMA4D,CRY2,PKMYT1,DLG3,TIPRL,SYTL2,SH2D4A,ARFGEF3,CHP1 |
| 2.594e-02 | -3.65 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 5698 | 617 | 16441 | 1675 |
DNAJC3,HEXB,RET,FBXO2,NRG2,IL18,MORF4L2,BARD1,CARD10,GRM5,ZNF275,CALM2,CDKN2C,PSMD1,KLF3,CRY2,PIK3CD,TIPARP,APOBEC3G,SMARCA2,TNIP1,TFAP2C,PRKAR2B,LOXL2,F12,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,HSPB1,E2F8,GAB1,HOXC13,GGA1,NUAK1,ITGA6,SOX9,RAB23,LMNA,ELF3,MARCH8,TFAP4,PAIP2B,MEGF8,NEK2,MAP3K9,MYDGF,NCAM1,MYLIP,NUP85,PPP6R1,SALL4,STAT4,PYM1,MYBL2,ELK1,TP53INP2,PSMA4,DCP2,NCOA3,ETS2,SEMA4D,SETD3,AURKA,STK39,GDF11,SERPINB1,ZNF502,NUP58,TMEM173,XDH,EGLN1,GRHL2,INPP5D,ACTR8,PTTG1,PRKACA,APC2,CCND1,ST5,CDH1,SP100,DACT1,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,CAMSAP3,RIPK2,APOBEC3D,FZD4,HTATIP2,CDCA2,GTF2A2,SNX12,ZNF618,NFIX,IRS2,CORO1C,WFS1,RGS14,MAPK12,NKX3-1,TNRC6C,CKAP2,ESRP1,SDC4,HABP4,CTSZ,PKN1,ETS1,GSTP1,TIPRL,HOXB2,NEO1,CTNNBIP1,DIRAS3,ITGB8,CTSC,CST3,BAX,TMBIM6,WWP1,MAPK11,MED22,CRTAP,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,PITX2,NR1D2,ACVRL1,NR4A3,ITGAV,HMGA1,CENPE,OSR1,USF2,SIGIRR,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,ELF5,PASK,MITF,ABCA2,DUSP10,MYBL1,ZNF462,PLK1,THRB,PCGF5,CD55,KCNIP3,CELSR2,CITED4,CBX6,NFE2L1,EZR,PRKRA,ZBTB7B,CDK1,OPTN,KDM4D,KLF12,HOXA9,ZNF367,PRKCDBP,KLF11,MAFF,PRKAA2,RUNX2,LMTK3,DNAJB2,RASA2,UBASH3B,PDCL,HES2,FBLN1,DAZAP1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,RGMB,ZNF320,STRADB,SCRIB,EIF2AK1,TCF7,CDK5R1,FOXD2,MAPKAPK2,CSF1,NLRC5,IFI6,USP43,AVPI1,NF2,HOXB7,UPF3B,FOXM1,CTDSPL,TP53,ERBB2,LPIN3,EMP2,STIL,BCAP31,SYTL2,IER3,RAD23A,TTC21B,PDGFA,LMO4,LHX6,PLCG2,BCL6,CDH3,NOTCH3,OAS3,EGLN3,CTDSP2,DVL2,CTH,SIRT1,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,DAG1,DNAJC10,PTPRJ,IDE,RBL1,STK38,EFNA5,IRF7,ZNF701,ARFGEF3,PINK1,CPEB4,MACC1,CD63,DAP,PSMD10,GTF3A,GDF15,NKRF,HMGN3,CRABP2,AIP,PARM1,PPP2R3A,FZD6,SH2D4A,CD109,FOXP2,GTF2F2,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,KLF9,SYK,TLE6,WBP5,NFE2L3,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,BBS2,MAPK8IP1,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,PPP2R3C,NDFIP1,UBE2C,HIPK3,ZBTB33,PKIA,PPP4R4,TXN,LGR4,SSH1,TSC22D3,PSME1,CAMK1D,CCNB1,ZNF823,CTGF,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,ZBTB18,ACVR1C,PBK,CASP9,AGO4,PIF1,SAV1,LDB2,POR,AHRR,HLF,PLK2,NKD1,PRDM5,EIF4EBP2,NFKBIZ,SERPINI1,F2RL1,TRAF5,LZTS1,DDX58,CDKN1C,DGKQ,PSIP1,MECOM,ITGA3,CYR61,BHLHE41,DAPK1,SORL1,RIMS2,TRAK2,SOCS5,EPB41L5,GFPT1,MMD,ZNF84,MFI2,CALM1,EPHA1,NFIB,RASA1,FAS,AP1AR,PRKAG2,PELI2,TCEAL4,FAM83D,SFMBT1,NR4A2,PER3,MAP3K5,SPRED1,FOXO6,DLGAP5,ARMCX3,S100A11,THRA,RPS6KA1,IQGAP1,CAST,APLP2,NOV,ZNF75D,FAM46A,CDKN1B,DAB2IP,PDE4D,MED30,NR2C1,FOXJ2,DRAP1,PRKCQ,SLC11A2,PKMYT1,PYGO1,RAD17,ATP1B1,H2AFV,SP4,FZD7,ZNF469,PRDM11,PPP2R5A,JAK1,STK26,NGFRAP1,SLC27A1,NRG1,KLF5,NR3C2,CBX7,PCOLCE,DEPDC1,HERC5,PBX3,APOBEC3H,FGF19,TEAD3,SIX4,SCML1,WWP2,SNTA1,E2F7,RNF128,PTEN,SGK3,ATP8B1,ERBB3,CNOT6L,CITED2,SPRY2,TRIM62,NCOA2,PDGFC,TGIF1,RASGRF1,FURIN,ZKSCAN2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,CPEB2,ESPL1,JARID2,RGMA,EMX1,CASP3,CRYM,CAMKK1,VARS2,ERP29,EPCAM,ZFYVE16,HSF2,GRHL1,ZCCHC12,SIVA1,PHTF1,DLG1,SLC39A10,RASGRP1,SP5,CYP1B1,TRIM8,ASCL5,USP18,ITCH,MDK,NEIL1,ZNF114,GPRC5B,MADD,ZNF165,CAB39,SP6,NR2C2,ZNF395,SERPINE2,PPP1R2,BVES,ETV5,ASB9,CALM3,TEC,PHLPP1,ZNF432,SUCO,C10orf54,RFX5,LRIF1,ETV7,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,RANBP9,SOX13,FECH,GNAS,BCAR3,ONECUT1,NUDT16,PLPP3,NFKBIA,CTSA,YOD1,JAK3,RARG,TOB1,PROM2,KLF7,GAS2L1,CCNE2,SORBS1,IL15,PSME2,HDAC11,TDRKH,IL27RA,OSR2,SS18,SVBP,ZNF687,SETDB2,FRYL,KIF14,TWIST1,ECE1,EPB41L4B,F2R,FRS3,CHP1,CKS2,MAP3K3,ZNF525,GLO1,ERBB2IP,DUSP4,CD40,MAP3K6,SOCS3,ARHGAP35,JADE1,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,PPP2R2D,GLIS3,ANXA3,SORT1,ARHGEF11,LRP4,MIER3,AES,TGFBR1,TRIB2,HMGXB4,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,ADORA1,MYCL,BMP7,TOX2,IQGAP3,NR4A1,GCLC,RC3H2,RGCC,MBNL3,RUNX3,TCEAL8,FOXL1,SWAP70,RAP2C,SPINT2,ARRB1,HOXB13,ZMIZ1,SOX8,AHR,ABCG1 |
| 2.595e-02 | -3.65 | protein dephosphorylation | biological process | GO:0006470 | 188 | 28 | 16441 | 1675 |
SSH3,MTM1,SSH1,DLGAP5,PPM1J,PTPRU,INPP5D,PTPN9,UBASH3B,CTDSPL,PHLPP1,DUSP4,SBF1,PPP2R3A,PTPRF,ATP1A1,PTPRJ,PTEN,PLPP3,PHLPP2,PALD1,PPP4R1,PPM1H,DLG1,DUSP10,PTPRE,CTDSP2,CPPED1 |
| 2.595e-02 | -3.65 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDM_UP | 193 | 28 | 17758 | 1761 |
ARHGEF3,TNIP1,NLRX1,PTGER4,OSGIN2,COL4A5,CD274,SYTL4,YES1,SPTLC2,CASP4,GATA2,SCG2,ZFP36,NFKBIA,ZNF704,POF1B,EGFL7,RAB20,NFKBIZ,PIM1,GEM,PTPRE,SLC27A3,TRIM62,MAFF,ACOT7,CYBRD1 |
| 2.595e-02 | -3.65 | GSE3982_CTRL_VS_LPS_4H_MAC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_DN | 193 | 28 | 17758 | 1761 |
CD99,CD55,USP18,EZR,HERC5,RUNX3,BLVRA,BCL2L1,CD40,CYB5A,FAS,SLCO4A1,BTG3,CYP1A1,SP100,ITGB8,PVRL2,RRBP1,IRF2,PITPNA,F2RL1,TIPARP,IFIH1,HIPK3,NDST3,MAFF,APOBEC3G,LAMP3 |
| 2.595e-02 | -3.65 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | 193 | 28 | 17758 | 1761 |
BIN1,COL9A3,BMF,ING1,B3GNT2,DGKQ,SELL,CR2,SESN1,RASA1,APPBP2,MSL1,FAAH,KCNK1,LMO4,MMP17,STK38,MADD,IRF7,NFKBIZ,SP6,ATP1B3,HLA-C,ALS2CL,RASGRP1,SNX30,SMAGP,KLF7 |
| 2.595e-02 | -3.65 | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | 193 | 28 | 17758 | 1761 |
THRB,ADD1,EPAS1,HEBP1,MPP1,RALBP1,FAM134A,ACO1,MGST2,SIX4,PIAS3,ANKRD10,PPP2R5A,SLC25A4,KCNN4,TMEM30A,BDH1,DLG1,PCYOX1,PNPLA6,FAM63A,TMEM51,AGBL5,ABCD1,CNOT6L,MPHOSPH9,MED22,STARD3NL |
| 2.595e-02 | -3.65 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_DN | 193 | 28 | 17758 | 1761 |
TM2D2,CCDC109B,UPF3B,GCLC,LPGAT1,UBE2A,KCTD12,NANS,SDC1,TCEAL8,C3orf58,SNX12,SIRPA,SUSD2,PRKAG2,ETS2,RNF128,SNX18,TIMM8A,CSNK1G1,STK38,SPINT2,ZNF704,RYK,TSPAN13,LRRK1,PTGES,TLE6 |
| 2.595e-02 | -3.65 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_UP | 193 | 28 | 17758 | 1761 |
MBP,KIF20A,CHCHD7,MRPS15,HEBP1,DAP,SLC25A13,GNE,HTATIP2,NDUFA4,LRRC1,ANLN,ELF3,CDH1,ELMO2,CDK16,KCNN4,OPN3,SRR,PCYOX1,NR4A3,FAM63A,TSPAN13,TECR,CCNB2,GLCCI1,SPRY2,ALDH3A2 |
| 2.595e-02 | -3.65 | GSE17721_4_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDM_UP | 193 | 28 | 17758 | 1761 |
MTM1,MRC2,PARP12,FRMD6,BCL9,SEPT6,HAL,OSGIN2,IL18,SNN,SAV1,SPTLC2,FAM46C,CYP26A1,PDGFA,RPS6KA2,PVRL2,SHROOM3,TRIM69,BHLHE41,RANBP1,MITF,MATN2,FAM102A,NDE1,ARF6,TRAF5,ATG4D |
| 2.596e-02 | -3.65 | ITSN1 (intersectin 1) | protein interactions | 6453 | 103 | 18 | 16036 | 1726 |
DLGAP1,PLK1,TRIM8,SCOC,PIK3R1,REPS1,SH3KBP1,GAREM2,PIK3AP1,RAB11FIP2,LMO4,SETD3,AGFG2,PIK3C2B,PDE4D,ARF6,CLIP2,SPRY2 |
| 2.601e-02 | -3.65 | GGATTA_V$PITX2_Q2 | MSigDB lists | GGATTA_V$PITX2_Q2 | 552 | 69 | 17758 | 1761 |
LTBP1,ARMCX3,TRIP10,FAM198B,FAM101B,SYTL2,RNF220,HSF2,MITF,SLC44A1,SRR,DUSP10,SCN3A,SMARCA2,FZD4,UTRN,RGAG1,TNS1,SP4,PIAS3,PGF,BFSP1,RBM47,MAP2,SIPA1L1,KLF5,SP6,ARF6,LIFR,NR3C2,NDST3,ARAP3,TM2D2,CPEB4,SOX9,DHRS3,ANO1,HPCAL4,SRPX2,C16orf74,ADD3,ADORA1,ITGA3,ZNRF2,LLGL2,CTSC,FLRT3,WNT3A,GAD1,CNPY3,SPRY2,RBMS2,IGSF3,EPB41L5,TGIF1,PDGFC,PLEKHA6,TCF7,ANKRD29,PRX,PITX2,ACVRL1,H1F0,ITPR1,MAP3K5,SEMA3A,OCLN,JARID2,GOLGB1 |
| 2.606e-02 | -3.65 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1488 | 174 | 16441 | 1675 |
LGR4,EPAS1,CNOT8,HEXB,RET,MORF4L2,CAMK1D,CCNB1,PDGFB,EPCAM,HSF2,GRHL1,NPNT,ZFP36,IL31RA,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,AHRR,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,DAZAP1,CYR61,GATA2,MDFIC,MYDGF,WNT3A,NUP85,ELK3,RGMB,SALL4,STAT4,MYBL2,ELK1,TP53INP2,NFIB,NCOA3,ONECUT1,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,TOB1,RARG,TMEM173,KLF7,GRHL2,ARMCX3,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CTH,SIRT1,AKT1,RIPK2,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,NRG1,IRF7,KLF5,GLIS3,ANXA3,TNRC6C,NKX3-1,PINK1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,TRIM62,NCOA2,NFE2L3,HES1,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,ARRB1,HMGA1,GPER1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 2.611e-02 | -3.65 | NAKAMURA_ADIPOGENESIS_LATE_DN | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_DN | 37 | 8 | 17758 | 1761 |
COL9A3,TIMP3,ITGA3,SERPINE2,CYR61,CALD1,GDF15,ITGAV |
| 2.611e-02 | -3.65 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | MSigDB lists | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | 37 | 8 | 17758 | 1761 |
CD55,RPS6KA2,AKT1,PTEN,INPP5D,RPS6KA1,PIK3CA,NR4A3 |
| 2.611e-02 | -3.65 | FRASOR_RESPONSE_TO_ESTRADIOL_UP | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_UP | 37 | 8 | 17758 | 1761 |
TOP2A,CYP1A1,PRSS23,RET,FOS,MYBL1,RASGRP1,CYP1B1 |
| 2.611e-02 | -3.65 | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN | MSigDB lists | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN | 37 | 8 | 17758 | 1761 |
KIF5B,CDK5RAP1,CASP9,SLC44A1,CITED2,PCTP,CPEB2,WBP5 |
| 2.611e-02 | -3.65 | PID_IL23_PATHWAY | MSigDB lists | PID_IL23_PATHWAY | 37 | 8 | 17758 | 1761 |
ITGA3,STAT4,NFKBIA,PIK3R1,PIK3CA,IL18,IL18R1,SOCS3 |
| 2.615e-02 | -3.64 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 160 | 24 | 17758 | 1761 |
MYL9,ATL1,SORT1,HSPG2,ZCCHC24,PDE5A,PRICKLE1,SAV1,FAM101B,SRPX2,ANO1,EDNRA,ENDOD1,ENPP1,CACHD1,TIMP3,AGPAT2,CALD1,SLC4A3,UACA,FHL1,TLN2,CEP41,MDFI |
| 2.617e-02 | -3.64 | RASGEF_CAT | prosite domains | PS50009 | 29 | 7 | 11866 | 1235 |
BCAR3,RASGRF1,RALGPS2,RASGEF1A,RAPGEF2,RASGRP1,RASGRP2 |
| 2.619e-02 | -3.64 | soft_tissue-fibrous_tissue_and_uncertain_origin-endometrial_stromal_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-endometrial_stromal_sarcoma | 24 | 6 | 17775 | 1757 |
ERBB2,SS18,FGFR2,PTEN,PIK3CA,TP53 |
| 2.619e-02 | -3.64 | pleomorphic | COSMIC cancer mutations | pleomorphic | 24 | 6 | 17775 | 1757 |
CDH1,IDH1,CHCHD7,PTEN,PIK3CA,TP53 |
| 2.619e-02 | -3.64 | endometrial_stromal_sarcoma | COSMIC cancer mutations | endometrial_stromal_sarcoma | 24 | 6 | 17775 | 1757 |
ERBB2,SS18,FGFR2,PTEN,PIK3CA,TP53 |
| 2.619e-02 | -3.64 | skin-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-benign_melanocytic_nevus-Spitz | 24 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.623e-02 | -3.64 | KEGG_CHRONIC_MYELOID_LEUKEMIA | MSigDB lists | KEGG_CHRONIC_MYELOID_LEUKEMIA | 73 | 13 | 17758 | 1761 |
CCND1,AKT1,SHC3,NFKBIA,PIK3R1,PIK3CA,TP53,HDAC1,CDKN1B,TGFBR1,PIK3CD,BCL2L1,MECOM |
| 2.623e-02 | -3.64 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | 73 | 13 | 17758 | 1761 |
RASGRF1,ARHGEF3,RHOA,GNB5,ARHGEF11,PIK3R1,PIK3CA,TIAM1,ARHGEF9,ABR,ARHGEF16,ARHGEF4,FGD1 |
| 2.623e-02 | -3.64 | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | MSigDB lists | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | 73 | 13 | 17758 | 1761 |
ITGA3,ITGB8,ITGA7,ITGA6,CACNA2D2,PKP2,TCF7,CACNA1D,ITGAV,SGCB,CACNB4,DAG1,LMNA |
| 2.623e-02 | -3.64 | ROSS_AML_WITH_AML1_ETO_FUSION | MSigDB lists | ROSS_AML_WITH_AML1_ETO_FUSION | 73 | 13 | 17758 | 1761 |
IL17RB,CCND1,ENDOD1,EPCAM,SLCO4A1,TWSG1,PELI2,RPS6KA1,ITPR1,CACNA2D2,EGFL7,KLF11,C15orf39 |
| 2.629e-02 | -3.64 | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | MSigDB lists | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | 51 | 10 | 17758 | 1761 |
B3GALT6,HS6ST1,HPSE,HSPG2,GUSB,SDC4,HS3ST3B1,SDC1,NDST3,GLCE |
| 2.629e-02 | -3.64 | GYORFFY_MITOXANTRONE_RESISTANCE | MSigDB lists | GYORFFY_MITOXANTRONE_RESISTANCE | 51 | 10 | 17758 | 1761 |
TOP2A,RASSF8,POPDC3,CYP4F11,OSTM1,CAMK1D,MAFF,RASA1,SYTL2,RRAGD |
| 2.629e-02 | -3.64 | BERNARD_PPAPDC1B_TARGETS_DN | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_DN | 51 | 10 | 17758 | 1761 |
ADD3,SERPINA1,MACC1,FGFR2,IL6ST,SH3BGRL2,SYT13,FAR2,ZMIZ1,RAP1GAP |
| 2.629e-02 | -3.64 | Phox | interpro domains | IPR001683 | 51 | 10 | 18293 | 1814 |
SNX18,SGK3,SNX16,PIK3C2B,PLD1,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 2.630e-02 | -3.64 | regulation of peptide secretion | biological process | GO:0002791 | 221 | 32 | 16441 | 1675 |
ILDR1,IQGAP1,CACNA2D2,HMGN3,ITPR2,SYTL4,PRKACA,SLC8B1,ANO1,NOV,ADORA1,CDK16,PASK,KCNS3,CACNA1D,MYRIP,MYT1,ACVR1C,SYBU,PRKAR2B,ITPR3,SLC25A5,GPLD1,IRS2,GNAS,SLC25A4,SYT7,ITPR1,ARRB1,EFNA5,SPCS3,GPER1 |
| 2.634e-02 | -3.64 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | MSigDB lists | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | 261 | 36 | 17758 | 1761 |
DDX58,HLA-F,HERC5,IL18,HLA-A,SP100,IL6ST,PIK3CA,IRF2,IFIT1,PIK3CD,HLA-C,OAS3,NCAM1,SYK,NUP85,MAP3K3,MX1,RIPK2,IFITM3,USP18,PIK3R1,PELI3,YES1,IFIT3,CDK1,SOCS3,IRS2,HLA-B,PLCG1,JAK1,PELI2,NOD2,IRF7,JAK3,IFI6 |
| 2.635e-02 | -3.64 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | 120 | 19 | 17775 | 1757 |
AKT1,VANGL1,RET,PIK3R1,TP53,ERBB2,TEX2,IDH1,GNA11,GNAS,CDKN2C,MUC16,PTEN,EXOC8,PIK3CA,NLRC5,ZMIZ1,ABCA1,CRTAP |
| 2.635e-02 | -3.64 | fat | COSMIC cancer mutations | fat | 120 | 19 | 17775 | 1757 |
SPEF2,SMARCA2,ARAP3,AKT1,GNE,TP53,ERBB2,VARS2,IDH1,SPTB,GNAS,SS18,CDH1,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 2.636e-02 | -3.64 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | 96 | 16 | 17758 | 1761 |
ADD1,ENO2,LITAF,ARHGDIB,MORF4L2,NPC2,ERP29,GNAS,TAPBP,NUCB1,RPL12,DDOST,METTL7A,UBE2J1,MDH1,LTA4H |
| 2.636e-02 | -3.64 | cellular carbohydrate metabolic process | biological process | GO:0044262 | 148 | 23 | 16441 | 1675 |
PGM1,GAA,B3GNT2,PPP1R2,UGP2,AKT1,CALM1,GNE,CALM3,NANS,ISYNA1,IDH1,CALM2,PRKAG2,PTEN,IL6ST,IMPAD1,GNPTAB,AKR1B1,PGM2L1,GOT1,PHKA2,ITPKA |
| 2.636e-02 | -3.64 | JNK cascade | biological process | GO:0007254 | 86 | 15 | 16441 | 1675 |
RIPK2,PTGER4,MAP3K9,NOD2,DUSP10,DAB2IP,MDFIC,MAP3K5,PKN1,TNFRSF19,GAB1,SYK,MAP3K6,MAPK8IP1,MDFI |
| 2.640e-02 | -3.63 | NAHEXCHNGR6 | prints domains | PR01088 | 3 | 2 | 4759 | 462 |
SLC9A6,SLC9A7 |
| 2.640e-02 | -3.63 | PNDRDTASEII | prints domains | PR00469 | 3 | 2 | 4759 | 462 |
AIFM3,AIFM2 |
| 2.640e-02 | -3.63 | ONCOGENEAML1 | prints domains | PR00967 | 3 | 2 | 4759 | 462 |
RUNX3,RUNX2 |
| 2.649e-02 | -3.63 | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | 185 | 27 | 17758 | 1761 |
DLGAP1,NKX3-1,PARP12,MFI2,LGALS3,STAT4,MGAT4B,CD274,HERC6,STEAP1,SH3KBP1,PPP2R3A,KDM4D,MUC16,SLC25A4,IGF1R,FGFR2,KCNN4,MFSD2A,SPINT2,ARVCF,ECE1,PACSIN1,EGLN3,HOOK1,MDFI,SNX7 |
| 2.649e-02 | -3.63 | GSE22886_NEUTROPHIL_VS_DC_UP | MSigDB lists | GSE22886_NEUTROPHIL_VS_DC_UP | 185 | 27 | 17758 | 1761 |
GCA,ING1,CRYM,CIT,TSC22D3,OGDHL,CXorf57,SELL,HERC5,BTN3A1,LRRC1,GPSM2,PDK3,STK17B,GPLD1,PHF7,SCG2,LHX6,FAM63A,ALPK3,GLB1L2,TINAGL1,CEP41,DGKG,SCYL3,RIMS2,XKR8 |
| 2.649e-02 | -3.63 | GSE27786_NKCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_DN | 185 | 27 | 17758 | 1761 |
DDX58,AMOTL2,SYPL1,PPP4R4,KLK10,NR3C1,ACVR1C,ARMC7,TMX4,STRADB,RANBP9,EDNRA,KLHL2,NOV,BANK1,RINL,PLK2,GALNS,TMC5,TFAP2A,ADIPOR1,RP2,SEMA3G,ARPC2,TIAM1,CPEB2,E2F8 |
| 2.649e-02 | -3.63 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 185 | 27 | 17758 | 1761 |
HMMR,TSC22D3,CASP9,NUB1,NFE2L1,C5orf30,RAB23,GGH,PRKAR2B,LRRC1,STIL,CYB5A,TMCC3,EPDR1,PIAS3,TWSG1,AGFG2,TWIST1,KLF5,TSPAN13,RELL1,EPB41L4A,TRAF5,TBC1D4,AHR,DVL2,FAM69A |
| 2.653e-02 | -3.63 | SAGIV_CD24_TARGETS_DN | MSigDB lists | SAGIV_CD24_TARGETS_DN | 44 | 9 | 17758 | 1761 |
APOBEC3B,TRIM8,CABP1,N4BP3,GDF15,CTTN,GEM,ULBP2,PDGFB |
| 2.653e-02 | -3.63 | KEGG_ABC_TRANSPORTERS | MSigDB lists | KEGG_ABC_TRANSPORTERS | 44 | 9 | 17758 | 1761 |
TAP1,ABCG2,ABCB1,ABCA2,ABCD1,ABCA1,ABCD4,ABCG1,ABCC1 |
| 2.653e-02 | -3.63 | MODULE_284 | MSigDB lists | MODULE_284 | 44 | 9 | 17758 | 1761 |
ZWINT,IGF1R,OSBPL3,NR4A3,EPHA1,PLXNA1,SLC1A3,PHLDA1,RAP1GAP |
| 2.653e-02 | -3.63 | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | MSigDB lists | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | 44 | 9 | 17758 | 1761 |
CENPA,DLGAP5,LGALS3,PSME2,SAT1,HMGA1,CCNB1,MELK,GM2A |
| 2.653e-02 | -3.63 | NABA_COLLAGENS | MSigDB lists | NABA_COLLAGENS | 44 | 9 | 17758 | 1761 |
COL9A3,COL6A2,COL13A1,COL6A1,COL18A1,COL7A1,COL4A5,COL16A1,COL12A1 |
| 2.653e-02 | -3.63 | MCDOWELL_ACUTE_LUNG_INJURY_UP | MSigDB lists | MCDOWELL_ACUTE_LUNG_INJURY_UP | 44 | 9 | 17758 | 1761 |
KLHL2,LTBP1,CYR61,NR4A1,ZFP36,NFKBIA,LITAF,FOS,PTGES |
| 2.657e-02 | -3.63 | LI_CISPLATIN_RESISTANCE_UP | MSigDB lists | LI_CISPLATIN_RESISTANCE_UP | 24 | 6 | 17758 | 1761 |
UACA,TWIST1,SMARCA2,EGLN3,IGF1R,CYP1B1 |
| 2.657e-02 | -3.63 | ER_GOLGI_INTERMEDIATE_COMPARTMENT | MSigDB lists | ER_GOLGI_INTERMEDIATE_COMPARTMENT | 24 | 6 | 17758 | 1761 |
NUCB1,NUCB2,PDIA6,RGMB,KDELR1,GOLGB1 |
| 2.657e-02 | -3.63 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | MSigDB lists | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | 24 | 6 | 17758 | 1761 |
MAPKAPK2,MAPK11,RPS6KA2,DUSP4,ELK1,RPS6KA1 |
| 2.657e-02 | -3.63 | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | MSigDB lists | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | 24 | 6 | 17758 | 1761 |
CALM2,CALM3,CTTN,CALM1,CALB2,DHX32 |
| 2.657e-02 | -3.63 | REACTOME_DARPP_32_EVENTS | MSigDB lists | REACTOME_DARPP_32_EVENTS | 24 | 6 | 17758 | 1761 |
CALM2,CALM3,PRKAR2B,PDE4D,PRKACA,CALM1 |
| 2.661e-02 | -3.63 | Sphingolipid metabolism | REACTOME pathways | R-HSA-428157 | 76 | 14 | 8202 | 867 |
ALDH3B1,ARSG,PLPP3,HEXB,ASAH1,CTSA,GLA,ARSB,SPTLC2,ARSK,CPTP,ALDH3A2,GM2A,SGPL1 |
| 2.662e-02 | -3.63 | leukocyte homeostasis | biological process | GO:0001776 | 64 | 12 | 16441 | 1675 |
CASP3,AKT1,SIVA1,RC3H2,BAX,PPP2R3C,PIK3CD,PKN1,CCNB2,JAK3,FAS,MECOM |
| 2.667e-02 | -3.62 | neurotrophin TRKA receptor binding | molecular function | GO:0005168 | 7 | 3 | 16491 | 1673 |
EFNA5,PLCG1,PIK3R1 |
| 2.667e-02 | -3.62 | G-protein coupled receptor kinase activity | molecular function | GO:0004703 | 7 | 3 | 16491 | 1673 |
GRK6,ADRBK1,ADRBK2 |
| 2.667e-02 | -3.62 | 1-phosphatidylinositol-4-phosphate 3-kinase activity | molecular function | GO:0035005 | 7 | 3 | 16491 | 1673 |
PIK3C2B,PIK3CD,PIK3CA |
| 2.667e-02 | -3.62 | galactosidase activity | molecular function | GO:0015925 | 7 | 3 | 16491 | 1673 |
GLB1L2,GLA,NAGA |
| 2.667e-02 | -3.62 | interleukin-17 receptor activity | molecular function | GO:0030368 | 7 | 3 | 16491 | 1673 |
IL17RB,IL27RA,IL6ST |
| 2.667e-02 | -3.62 | xylosyltransferase activity | molecular function | GO:0042285 | 7 | 3 | 16491 | 1673 |
XYLT2,XYLT1,GYLTL1B |
| 2.667e-02 | -3.62 | cytochrome-b5 reductase activity, acting on NAD(P)H | molecular function | GO:0004128 | 7 | 3 | 16491 | 1673 |
NQO1,POR,CYB5R2 |
| 2.667e-02 | -3.62 | procollagen-proline dioxygenase activity | molecular function | GO:0019798 | 7 | 3 | 16491 | 1673 |
P3H2,P4HA2,P4HA3 |
| 2.667e-02 | -3.62 | thyroid hormone receptor activity | molecular function | GO:0004887 | 7 | 3 | 16491 | 1673 |
THRB,THRA,NR4A3 |
| 2.668e-02 | -3.62 | Ion channel transport | REACTOME pathways | R-HSA-983712 | 198 | 30 | 8202 | 867 |
CLCN3,OSTM1,ATP9A,TSC22D3,ATP8A1,FXYD3,ANO6,ATP2C2,GABRG2,ANO9,ATP8B3,ATP1B1,ATP10D,ANO1,TTYH3,ATP13A2,ATP6V0B,SCNN1A,ATP1A1,ATP7B,SGK3,SGK1,ATP8B1,TRPC1,WWP1,ATP1B3,ANO4,ARHGEF9,TPCN1,ATP2B1 |
| 2.671e-02 | -3.62 | chaperone binding | molecular function | GO:0051087 | 79 | 14 | 16491 | 1673 |
HLA-B,DNAJC10,HES1,ATP1A1,GNB5,CTSC,DNAJC3,DNAJB2,AMFR,TBCD,TP53,BAX,CDKN1B,ERP29 |
| 2.672e-02 | -3.62 | AAAYRNCTG_UNKNOWN | MSigDB lists | AAAYRNCTG_UNKNOWN | 348 | 46 | 17758 | 1761 |
LMO7,LTBP1,SCN5A,SCOC,TSC22D3,COL4A5,BCL2L1,PDGFB,TRIM68,TSPAN7,SIRPA,PPP2R3A,TFAP4,FOXP2,SESN3,ADD3,ZNF687,SHC3,ARSG,MGAT4A,NEK2,ANKRD12,MANF,CITED2,BTBD3,SMARCA2,TRIM8,PODXL2,BCL9,PRKCQ,TNS1,ROR1,DUSP4,SPTLC2,TP53INP2,COL12A1,MAP2,NMI,KLF5,NRG1,MAP3K5,ARPC2,CAPN1,DEF6,CYBRD1,RNF146 |
| 2.677e-02 | -3.62 | glycosaminoglycan biosynthetic process | biological process | GO:0006024 | 109 | 18 | 16441 | 1675 |
CHSY3,B3GALT6,SLC35D2,B3GNT7,B3GNT2,HSPG2,XYLT1,SDC4,B4GALT4,DSE,SDC1,CHPF,GLCE,HS6ST1,XYLT2,HS3ST3B1,ST3GAL1,NDST3 |
| 2.680e-02 | -3.62 | phosphatase activity | molecular function | GO:0016791 | 264 | 37 | 16491 | 1673 |
MTM1,DLGAP5,SSH1,PPM1J,UBASH3B,TMEM55B,INPP5D,CTDSPL,PHLPP1,LPIN3,SBF1,PLPPR4,PTEN,ALPP,IMPAD1,PAPL,PALD1,PPP4R1,DLG1,DUSP10,PIKFYVE,MINPP1,PTPRE,CTDSP2,SSH3,PTPRU,PTPN9,DUSP4,PTPRF,NUDT16,PTPRJ,ATP1A1,PLPP3,PHLPP2,PPM1H,INPP4B,CPPED1 |
| 2.681e-02 | -3.62 | GRB2 (growth factor receptor bound protein 2) | protein interactions | 2885 | 535 | 72 | 16036 | 1726 |
REPS2,HSPG2,INPP5D,SLC25A13,RPS6KA1,IQGAP1,RET,HEXB,DNAJB11,ERBB2,FTH1,PSME1,REPS1,SH3KBP1,SS18,ELMO2,WDR44,SHC3,IL6ST,PIK3CA,CDKN1B,CTTN,PDE4D,PTPRE,FRS3,CKS2,DOCK4,ITCH,SLC25A5,ZBTB7B,DAG1,ARHGAP35,IRS2,PLCG1,PTPRJ,JAK1,MAP2,AXL,PIK3C2B,GAB1,MAPK12,ITGA6,UBASH3B,EPS8,SELL,CALM3,AES,NCKAP1,TEC,MERTK,SIRPA,SH2D4A,SNTA1,PIK3AP1,SNX18,CALD1,ADAM15,ERBB3,SPRY2,SYK,DLGAP1,PIK3R1,STRADB,ELK1,BCAR1,TCEAL8,RASA1,GAREM2,H1F0,FGD6,LRRK1,HIPK3 |
| 2.683e-02 | -3.62 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 273 | 40 | 16036 | 1726 |
PPP1R2,ARHGEF11,RPS6KA1,TP53,PHLPP1,HDAC6,PRKACA,TOP2A,CCND1,KIF5B,RNF220,CDH1,DPYSL2,LMO4,BHLHE41,MITF,SGK3,SGK1,NOTCH3,PDE4D,TRAK2,CAMSAP3,AKT1,MPP1,PIK3R1,NUB1,NFE2L1,NIN,NCOA3,MID1IP1,ANKRD6,DNM1L,DBI,FAM83D,ARRB1,TLE1,AURKA,KLF5,FZD5,NRBP1 |
| 2.684e-02 | -3.62 | arylsulfatase activity | molecular function | GO:0004065 | 12 | 4 | 16491 | 1673 |
ARSB,ARSG,ARSK,SULF2 |
| 2.684e-02 | -3.62 | neurotrophin receptor binding | molecular function | GO:0005165 | 12 | 4 | 16491 | 1673 |
EFNA5,PLCG1,NGFRAP1,PIK3R1 |
| 2.686e-02 | -3.62 | ACTININ_2 | prosite domains | PS00020 | 23 | 6 | 11866 | 1235 |
CLMN,SPTBN5,SPTB,SYNE2,UTRN,PLS3 |
| 2.686e-02 | -3.62 | ACTININ_1 | prosite domains | PS00019 | 23 | 6 | 11866 | 1235 |
CLMN,SPTBN5,SPTB,SYNE2,UTRN,PLS3 |
| 2.686e-02 | -3.62 | FZ | prosite domains | PS50038 | 23 | 6 | 11866 | 1235 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6 |
| 2.687e-02 | -3.62 | BCL10 (B-cell CLL/lymphoma 10) | protein interactions | 8915 | 54 | 11 | 16036 | 1726 |
IL15RA,AKT1,RIPK2,PELI2,NFKBIA,CASP9,PRKCQ,SLC20A1,CARD10,PRRG4,SOCS3 |
| 2.689e-02 | -3.62 | meningothelial | COSMIC cancer mutations | meningothelial | 18 | 5 | 17775 | 1757 |
CDKN2C,NF2,AKT1,PTEN,PIK3CA |
| 2.689e-02 | -3.62 | meninges-meningioma-meningothelial | COSMIC cancer mutations | meninges-meningioma-meningothelial | 18 | 5 | 17775 | 1757 |
CDKN2C,NF2,AKT1,PTEN,PIK3CA |
| 2.689e-02 | -3.62 | dysplasia | COSMIC cancer mutations | dysplasia | 18 | 5 | 17775 | 1757 |
GNAS,ERBB2,IDH1,PTEN,TP53 |
| 2.689e-02 | -3.62 | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | 18 | 5 | 17775 | 1757 |
ERBB2,CHCHD7,PTEN,PIK3CA,TP53 |
| 2.689e-02 | -3.62 | ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | ex-pleomorphic_adenoma_carcinoma | 18 | 5 | 17775 | 1757 |
ERBB2,CHCHD7,PTEN,PIK3CA,TP53 |
| 2.690e-02 | -3.62 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 270 | 37 | 17758 | 1761 |
CD99,SERPINE2,CTDSPL,PDIA5,ARFGEF1,C5orf30,DHRS3,TSPAN7,LGALS3BP,BTG3,RPS6KA2,DAPK1,SORL1,SCN2A,MAST4,FAH,ARAP2,STAT4,LYRM1,PRKCQ,ATP1B1,YES1,SESN1,LHFPL2,MDK,ENDOD1,PGF,JAK1,H1F0,GNPTAB,SIPA1L1,ABCB1,CLMN,EGFL7,ITGAV,ICOSLG,ISOC1 |
| 2.695e-02 | -3.61 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma) | protein interactions | 7532 | 370 | 52 | 16036 | 1726 |
LMO7,CASP3,CDK17,TBC1D1,CKAP2,FRMD6,CAMKK1,DCAF7,TP53,PKP2,KIF23,FBXO6,NCKAP1,LBR,RASSF8,KIF5B,WEE1,SS18,ATP6V0B,IGF1R,RALGPS2,CDK16,FRYL,ZFP36,OSBPL3,FAM13B,N4BP3,KLC3,TRIM21,CDKN1B,ALDH7A1,SIMC1,TIAM1,MPHOSPH9,FARP2,MAP3K3,ING1,AKT1,PIK3R1,KIF1C,PRKCQ,MCFD2,OPTN,IRS2,RAB11FIP2,SH3BP4,FGD6,ARRB1,CFAP20,NDE1,SHROOM2,TBC1D4 |
| 2.696e-02 | -3.61 | negative regulation of stem cell differentiation | biological process | GO:2000737 | 43 | 9 | 16441 | 1675 |
HES1,NCOA3,BMP7,VASN,PRICKLE1,DAB2IP,WNT3A,TRIM62,SIX4 |
| 2.696e-02 | -3.61 | peptidyl-threonine phosphorylation | biological process | GO:0018107 | 43 | 9 | 16441 | 1675 |
ADRBK1,AKT1,STK39,TGFBR1,PKN1,PRKACA,HIPK3,CDK1,CDK5R1 |
| 2.697e-02 | -3.61 | spindle microtubule | cellular component | GO:0005876 | 58 | 11 | 17570 | 1756 |
PLK1,CALM2,CAPN6,CALM1,PARP4,TUBG1,CALM3,AURKA,NUSAP1,KIF11,CDK1 |
| 2.698e-02 | -3.61 | regulation of endocytic recycling | biological process | GO:2001135 | 7 | 3 | 16441 | 1675 |
SORL1,BVES,EHD1 |
| 2.698e-02 | -3.61 | regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | GO:2000794 | 7 | 3 | 16441 | 1675 |
FGFR2,NFIB,SOX9 |
| 2.698e-02 | -3.61 | glycoside catabolic process | biological process | GO:0016139 | 7 | 3 | 16441 | 1675 |
FUCA1,GLA,NAGA |
| 2.698e-02 | -3.61 | transformed cell apoptotic process | biological process | GO:0006927 | 7 | 3 | 16441 | 1675 |
DAB2IP,FAS,BAX |
| 2.698e-02 | -3.61 | peptidyl-lysine deacetylation | biological process | GO:0034983 | 7 | 3 | 16441 | 1675 |
SIRT1,HDAC6,HDAC9 |
| 2.698e-02 | -3.61 | extraembryonic membrane development | biological process | GO:1903867 | 7 | 3 | 16441 | 1675 |
E2F7,FZD5,E2F8 |
| 2.698e-02 | -3.61 | multivesicular body sorting pathway | biological process | GO:0071985 | 7 | 3 | 16441 | 1675 |
EXPH5,SYTL4,RAB27B |
| 2.698e-02 | -3.61 | transmembrane receptor protein tyrosine phosphatase signaling pathway | biological process | GO:0007185 | 7 | 3 | 16441 | 1675 |
PTPRF,PTPRU,PTPRE |
| 2.698e-02 | -3.61 | cardiac neural crest cell development involved in heart development | biological process | GO:0061308 | 7 | 3 | 16441 | 1675 |
PITX2,TWIST1,HES1 |
| 2.698e-02 | -3.61 | regulation of protein deubiquitination | biological process | GO:0090085 | 7 | 3 | 16441 | 1675 |
TRIM21,ITCH,DNAJB2 |
| 2.698e-02 | -3.61 | positive regulation of antimicrobial humoral response | biological process | GO:0002760 | 7 | 3 | 16441 | 1675 |
KLK7,KLK5,NOD2 |
| 2.698e-02 | -3.61 | mammary gland involution | biological process | GO:0060056 | 7 | 3 | 16441 | 1675 |
ERBB2,CAPN1,ELF3 |
| 2.698e-02 | -3.61 | kidney interstitial fibroblast differentiation | biological process | GO:0072071 | 7 | 3 | 16441 | 1675 |
HES1,OSR1,PDGFB |
| 2.698e-02 | -3.61 | cardiac neural crest cell development involved in outflow tract morphogenesis | biological process | GO:0061309 | 7 | 3 | 16441 | 1675 |
PITX2,TWIST1,HES1 |
| 2.698e-02 | -3.61 | intracellular cholesterol transport | biological process | GO:0032367 | 7 | 3 | 16441 | 1675 |
NPC2,ABCA1,ABCG1 |
| 2.698e-02 | -3.61 | dendritic spine maintenance | biological process | GO:0097062 | 7 | 3 | 16441 | 1675 |
CTTN,ITGA3,ITPKA |
| 2.698e-02 | -3.61 | cardiac neural crest cell differentiation involved in heart development | biological process | GO:0061307 | 7 | 3 | 16441 | 1675 |
PITX2,TWIST1,HES1 |
| 2.698e-02 | -3.61 | negative regulation of protein export from nucleus | biological process | GO:0046826 | 7 | 3 | 16441 | 1675 |
TXN,SP100,BARD1 |
| 2.698e-02 | -3.61 | chorion development | biological process | GO:0060717 | 7 | 3 | 16441 | 1675 |
E2F7,FZD5,E2F8 |
| 2.700e-02 | -3.61 | CARBOXYLIC_ACID_METABOLIC_PROCESS | MSigDB lists | CARBOXYLIC_ACID_METABOLIC_PROCESS | 177 | 26 | 17758 | 1761 |
FADS2,GCLM,ALDH6A1,GCLC,GNE,PPARA,ACO1,SLC7A2,IDH1,CYP39A1,CYP4F3,SLC6A6,ALDH5A1,ACADSB,SLC27A6,AGPAT2,FAAH,ECI2,ADIPOR1,GOT1,ACOX2,LTA4H,GAD1,PTGES,MCCC2,FAH |
| 2.700e-02 | -3.61 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 177 | 26 | 17758 | 1761 |
ERLEC1,LRRFIP2,PSMB4,TBC1D1,UBE2A,SLC36A4,NANS,DSE,FAM81A,TYMP,MDM1,CYP1A1,SLC4A4,ZNRF2,CSF1,SIPA1L1,DBI,PLEKHG1,NR4A3,SELK,ACSL4,GLA,DGKG,CKAP4,STARD3NL,NXT2 |
| 2.700e-02 | -3.61 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 26 | 17758 | 1761 |
COQ10B,RASA2,HEXB,TESK2,DHX8,SLC36A4,FTH1,MORF4L2,NPHP3,HLA-A,ARF4,APPBP2,VPS26A,AKIRIN1,SIPA1L2,SETDB2,TRIM69,ITPR1,SPINT2,SELK,SPCS3,MANF,NDFIP1,ST3GAL1,DVL2,GOLGB1 |
| 2.700e-02 | -3.61 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 177 | 26 | 17758 | 1761 |
MFI2,LONRF3,LGALS3,GNPDA1,UBASH3B,LHFPL2,S100A2,STX3,BCAR3,ANKRD10,SLCO4A1,SCARB2,PRKAG2,PPP2R5A,EFR3A,CORO1C,CSF1,ADCK2,SGK1,BRI3,NR4A2,GEM,PTPRE,SPRY2,WBP5,RRAGD |
| 2.700e-02 | -3.61 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 177 | 26 | 17758 | 1761 |
ACACB,SORBS1,FAM169A,DEPDC1,CDH22,TBC1D1,ATP9A,SERTAD4,GRIN1,STMN3,HERC5,TCF7,SAMD9,ATP1B1,IFIT3,ASB13,FAM101B,FANCI,TFAP2A,MDFIC,OAS3,RCAN3,APOBEC3G,RARG,CYBRD1,SNX7 |
| 2.703e-02 | -3.61 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | 112 | 18 | 17758 | 1761 |
HAL,SELL,HERC5,TCF7,IL13RA1,SLC1A3,HLA-B,ADD3,FAAH,RPL39,DACT1,BCL6,SH3BP4,SORL1,IRF7,HLA-C,PTPRE,SGCB |
| 2.703e-02 | -3.61 | REACTOME_TOLL_RECEPTOR_CASCADES | MSigDB lists | REACTOME_TOLL_RECEPTOR_CASCADES | 112 | 18 | 17758 | 1761 |
SIGIRR,RIPK2,RPS6KA1,PELI3,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,PELI2,NFKBIA,PLCG2,NOD2,MAPK11,IRF7,LGMN,CNPY3 |
| 2.705e-02 | -3.61 | PI3K_rbd | pfam domains | PF00794 | 7 | 3 | 16629 | 1696 |
PIK3C2B,PIK3CD,PIK3CA |
| 2.705e-02 | -3.61 | Anoct_dimer | pfam domains | PF16178 | 7 | 3 | 16629 | 1696 |
ANO4,ANO1,ANO6 |
| 2.705e-02 | -3.61 | Branch | pfam domains | PF02485 | 7 | 3 | 16629 | 1696 |
XYLT2,XYLT1,GCNT1 |
| 2.705e-02 | -3.61 | Furin-like | pfam domains | PF00757 | 7 | 3 | 16629 | 1696 |
ERBB2,ERBB3,IGF1R |
| 2.705e-02 | -3.61 | ACBP | pfam domains | PF00887 | 7 | 3 | 16629 | 1696 |
ACBD5,ECI2,DBI |
| 2.705e-02 | -3.61 | TGF_beta_GS | pfam domains | PF08515 | 7 | 3 | 16629 | 1696 |
TGFBR1,ACVRL1,ACVR1C |
| 2.705e-02 | -3.61 | Recep_L_domain | pfam domains | PF01030 | 7 | 3 | 16629 | 1696 |
ERBB2,ERBB3,IGF1R |
| 2.705e-02 | -3.61 | TB | pfam domains | PF00683 | 7 | 3 | 16629 | 1696 |
LTBP1,LTBP2,LTBP3 |
| 2.711e-02 | -3.61 | SABATES_COLORECTAL_ADENOMA_UP | MSigDB lists | SABATES_COLORECTAL_ADENOMA_UP | 128 | 20 | 17758 | 1761 |
NFE2L3,KLK10,NQO1,S100A11,NOTUM,GPSM2,DUSP4,ANLN,PHLDA1,S100A2,SRPX2,SLC6A6,GRHL1,FABP6,NKD1,CDH3,TACSTD2,IGFBP2,ETV4,SP5 |
| 2.711e-02 | -3.61 | KEGG_AXON_GUIDANCE | MSigDB lists | KEGG_AXON_GUIDANCE | 128 | 20 | 17758 | 1761 |
DPYSL5,SEMA6B,RHOA,EPHA4,PLXNA1,EPHA1,EFNB1,RASA1,SEMA4D,DPYSL2,RGS3,LIMK1,NTN4,EFNA5,SEMA3G,EPHB4,UNC5B,SEMA3A,L1CAM,SEMA3B |
| 2.711e-02 | -3.61 | MODULE_324 | MSigDB lists | MODULE_324 | 128 | 20 | 17758 | 1761 |
ANXA3,LTBP1,PLSCR1,S100A11,S100A4,CALB2,RET,S100A2,FBLN1,TP53I3,MYL12A,PLS3,CA2,CDH1,SCG2,PLCG2,BMP1,CDH3,LTBP2,S100A13 |
| 2.712e-02 | -3.61 | V$AML_Q6 | MSigDB lists | V$AML_Q6 | 253 | 35 | 17758 | 1761 |
RUNX2,ADD1,HAPLN3,GALNT12,TSC22D3,PRKACA,LTBP3,CYR61,SLC16A6,VASN,BMP7,MKRN3,KCNN4,FAM63A,BCL6,CNNM4,TACSTD2,TSPAN13,NR4A1,SNTB2,PIK3R1,TCF7,PPP1R14C,RNF19B,BCAR3,PGF,PDLIM3,RBL1,MADD,FAM117A,GRIN2D,SP6,NR3C2,FGD1,RGMA |
| 2.713e-02 | -3.61 | ARGGGTTAA_UNKNOWN | MSigDB lists | ARGGGTTAA_UNKNOWN | 120 | 19 | 17758 | 1761 |
CYP26B1,HES1,B3GNT7,BLVRB,KLK6,TNS1,ATP1B1,CRABP2,DHRS3,PDGFB,EPN3,CDKN2C,PLEKHG6,KLF12,PVRL2,SLC16A6,AXL,DUSP10,RARG |
| 2.715e-02 | -3.61 | positive regulation of nuclear division | biological process | GO:0051785 | 57 | 11 | 16441 | 1675 |
PLK1,DLGAP5,IGF1R,PTEN,CDCA5,RGCC,AURKA,NUSAP1,PDGFB,UBE2C,ESPL1 |
| 2.721e-02 | -3.60 | V$HSF2_01 | MSigDB lists | V$HSF2_01 | 236 | 33 | 17758 | 1761 |
IER5L,CACNA2D2,MORF4L2,VASH1,PDGFB,SPTB,BCAP31,SIX4,IRF2BPL,SHC3,TSPAN6,BCL6,CACNA1D,GAD1,RIMS2,ADAMTS2,TGIF1,TRIM8,BCL9,FOS,LHFPL2,CDK5R1,RASGRP2,HLA-B,COL13A1,MAP2,NR4A3,FHL1,COL16A1,ACOT7,CMTM4,NR2C2,JARID2 |
| 2.722e-02 | -3.60 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 793 | 95 | 17775 | 1757 |
LMO7,EXPH5,IQGAP1,TP53,MORF4L2,ITPR2,BARD1,APC2,SLC20A1,SPTB,SH3KBP1,ZFYVE16,MUC16,SCNN1A,CYP2S1,PLCG2,STEAP2,BCL6,PIK3CA,CTTN,RASGEF1A,RCAN3,PTPRE,MYRIP,PDIA6,MYO5B,MX1,SPEF2,TRIM8,RGAG1,DUSP4,IDH1,DOCK5,SP4,PPP2R5A,DNM1L,WFS1,SPTBN5,MLKL,ARF6,ARAP3,CDKN1C,ITGA6,EPS8,SAMD9,SLC1A3,CNTNAP2,ADAMTSL4,SLC25A43,ETS1,TSPAN7,PRRG4,ZNF432,ADRBK1,FRY,PTEN,BMP7,PRKG1,SGK1,CD70,PIM1,CNOT6L,NCEH1,SGCB,ETV7,RIMS2,TRAK2,SYPL1,ARAP2,LCA5,PSMB4,SALL4,NR3C1,FAM160A1,CXorf57,UBE2A,GRTP1,KIF11,PRX,FAS,HLA-B,RPL12,FAT4,SERPINA1,TRIM69,PELI2,ZNF214,UTP14C,NFKBIA,ITPR1,ETAA1,ITGAV,TBC1D4,EGLN1,TLL2 |
| 2.722e-02 | -3.60 | positive regulation of Rho protein signal transduction | biological process | GO:0035025 | 12 | 4 | 16441 | 1675 |
ARRB1,ADGRG1,F2R,F2RL1 |
| 2.722e-02 | -3.60 | positive regulation of astrocyte differentiation | biological process | GO:0048711 | 12 | 4 | 16441 | 1675 |
BIN1,HES1,SERPINE2,IL6ST |
| 2.722e-02 | -3.60 | regulation of extracellular matrix disassembly | biological process | GO:0010715 | 12 | 4 | 16441 | 1675 |
MFI2,ETS1,DDR1,CST3 |
| 2.722e-02 | -3.60 | eyelid development in camera-type eye | biological process | GO:0061029 | 12 | 4 | 16441 | 1675 |
HDAC1,TWIST1,OSR2,TFAP2A |
| 2.722e-02 | -3.60 | iron ion import | biological process | GO:0097286 | 12 | 4 | 16441 | 1675 |
SLC11A2,MFI2,STEAP1,STEAP2 |
| 2.722e-02 | -3.60 | carnitine transmembrane transport | biological process | GO:1902603 | 12 | 4 | 16441 | 1675 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 2.722e-02 | -3.60 | ossification involved in bone maturation | biological process | GO:0043931 | 12 | 4 | 16441 | 1675 |
RHOA,FAT4,SEMA4D,ANO6 |
| 2.722e-02 | -3.60 | pigment accumulation | biological process | GO:0043476 | 12 | 4 | 16441 | 1675 |
RAB38,SHROOM2,CD63,SHROOM3 |
| 2.722e-02 | -3.60 | regulation of peroxisome proliferator activated receptor signaling pathway | biological process | GO:0035358 | 12 | 4 | 16441 | 1675 |
SIRT1,TWIST1,CITED2,PLIN5 |
| 2.722e-02 | -3.60 | regulation of phospholipid biosynthetic process | biological process | GO:0071071 | 12 | 4 | 16441 | 1675 |
PDGFA,SLC27A1,IDH1,PDGFB |
| 2.722e-02 | -3.60 | cellular pigment accumulation | biological process | GO:0043482 | 12 | 4 | 16441 | 1675 |
RAB38,SHROOM2,CD63,SHROOM3 |
| 2.722e-02 | -3.60 | glycosphingolipid catabolic process | biological process | GO:0046479 | 12 | 4 | 16441 | 1675 |
GLA,NAGA,GM2A,HEXB |
| 2.723e-02 | -3.60 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | MSigDB lists | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | 18 | 5 | 17758 | 1761 |
PIK3CD,YES1,SYK,PIK3R1,PIK3CA |
| 2.723e-02 | -3.60 | KANG_DOXORUBICIN_RESISTANCE_DN | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_DN | 18 | 5 | 17758 | 1761 |
WWP1,NCOA3,NR1D2,ATP2B1,PCYOX1 |
| 2.723e-02 | -3.60 | NAM_FXYD5_TARGETS_DN | MSigDB lists | NAM_FXYD5_TARGETS_DN | 18 | 5 | 17758 | 1761 |
FXYD5,FTH1,AXL,APPBP2,MCCC2 |
| 2.723e-02 | -3.60 | BOWIE_RESPONSE_TO_TAMOXIFEN | MSigDB lists | BOWIE_RESPONSE_TO_TAMOXIFEN | 18 | 5 | 17758 | 1761 |
MX1,IRF7,IFIT1,IFIT3,IFI6 |
| 2.723e-02 | -3.60 | MAHADEVAN_RESPONSE_TO_MP470_DN | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_DN | 18 | 5 | 17758 | 1761 |
GDF15,CTTN,GEM,CYR61,MAFF |
| 2.723e-02 | -3.60 | SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | 18 | 5 | 17758 | 1761 |
HS6ST1,GCLM,HS3ST3B1,GCLC,GLCE |
| 2.723e-02 | -3.60 | MODULE_354 | MSigDB lists | MODULE_354 | 18 | 5 | 17758 | 1761 |
AHCY,CA2,OAT,CA8,CTH |
| 2.723e-02 | -3.60 | CHOI_ATL_CHRONIC_VS_ACUTE_DN | MSigDB lists | CHOI_ATL_CHRONIC_VS_ACUTE_DN | 18 | 5 | 17758 | 1761 |
MDH1,NCOA3,GTF3A,CMTM6,CTDSP2 |
| 2.723e-02 | -3.60 | DAZARD_UV_RESPONSE_CLUSTER_G28 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G28 | 18 | 5 | 17758 | 1761 |
TACSTD2,CTGF,CITED2,H1FX,IER3 |
| 2.723e-02 | -3.60 | BIOCARTA_ETS_PATHWAY | MSigDB lists | BIOCARTA_ETS_PATHWAY | 18 | 5 | 17758 | 1761 |
ETS2,FOS,RBL1,ETS1,CSF1 |
| 2.723e-02 | -3.60 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | 18 | 5 | 17758 | 1761 |
B4GALT4,MGAT4A,MGAT5,FUT8,MGAT4B |
| 2.723e-02 | -3.60 | BIOCARTA_NGF_PATHWAY | MSigDB lists | BIOCARTA_NGF_PATHWAY | 18 | 5 | 17758 | 1761 |
PLCG1,ELK1,FOS,PIK3R1,PIK3CA |
| 2.723e-02 | -3.60 | BIOCARTA_MEF2D_PATHWAY | MSigDB lists | BIOCARTA_MEF2D_PATHWAY | 18 | 5 | 17758 | 1761 |
CALM2,HDAC1,CALM3,CABIN1,CALM1 |
| 2.723e-02 | -3.60 | SABATES_COLORECTAL_ADENOMA_SIZE_UP | MSigDB lists | SABATES_COLORECTAL_ADENOMA_SIZE_UP | 18 | 5 | 17758 | 1761 |
STMN3,LAMP2,TIMP3,SLC20A1,BCL6 |
| 2.723e-02 | -3.60 | MODULE_294 | MSigDB lists | MODULE_294 | 18 | 5 | 17758 | 1761 |
CA2,ACADSB,CA8,HAL,CTH |
| 2.723e-02 | -3.60 | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP | MSigDB lists | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP | 18 | 5 | 17758 | 1761 |
LIMCH1,STK39,LCA5,CDKN1C,PCSK5 |
| 2.723e-02 | -3.60 | KOBAYASHI_EGFR_SIGNALING_6HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_6HR_DN | 18 | 5 | 17758 | 1761 |
CCND1,DUSP4,CYR61,MAFF,IER3 |
| 2.723e-02 | -3.60 | ZEMBUTSU_SENSITIVITY_TO_VINCRISTINE | MSigDB lists | ZEMBUTSU_SENSITIVITY_TO_VINCRISTINE | 18 | 5 | 17758 | 1761 |
FOXO6,ATP1B1,ETS1,BARD1,OSGIN1 |
| 2.723e-02 | -3.60 | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_UP | MSigDB lists | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_UP | 18 | 5 | 17758 | 1761 |
CTSZ,PINK1,ITPKA,SHROOM2,FAS |
| 2.723e-02 | -3.60 | SPINDLE_POLE | MSigDB lists | SPINDLE_POLE | 18 | 5 | 17758 | 1761 |
TUBG1,BUB1,DLGAP5,NDE1,KIF11 |
| 2.730e-02 | -3.60 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1796 | 207 | 16441 | 1675 |
LGR4,EPAS1,DNAJC3,HEXB,RET,ARFGEF1,MORF4L2,CAMK1D,HDAC6,PDGFB,CALM2,EPCAM,HSF2,CTGF,GRHL1,NPNT,IL31RA,MITF,FOSB,PASK,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,POR,ARF4,EDNRA,AHRR,MDK,MID1IP1,KLF12,NOD2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,CALM3,PSIP1,LMNA,MECOM,ELF3,TFAP4,IGF1R,CYR61,GATA2,NEK2,SUCO,MDFIC,MYDGF,WNT3A,NUP85,GPR161,ELK3,RGMB,SALL4,STAT4,CALM1,PYM1,MYBL2,ELK1,TP53INP2,NFIB,PLIN5,GNAS,MAPKAPK2,ONECUT1,NCOA3,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,SORBS1,ARMCX3,GRHL2,UPF3B,FOXM1,IL15,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,PDGFA,SS18,CDH1,SP100,LMO4,CDH3,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CHP1,CTH,SIRT1,CLCN3,TIMP2,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,IRS2,JADE1,RBL1,WFS1,KLF5,NRG1,IRF7,ABCA1,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,PARM1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,CST3,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,SYK,TRIM62,NCOA2,NFE2L3,PDGFC,HES1,RHOA,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,EIF5A2,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,GPLD1,PITX2,FGFR2,ACVRL1,NR1D2,NR4A3,ARRB1,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,ABCG1,RGMA |
| 2.731e-02 | -3.60 | positive regulation of dendrite development | biological process | GO:1900006 | 50 | 10 | 16441 | 1675 |
GRN,FOXO6,BHLHB9,BMP7,EPHA4,DAB2IP,NRG1,ITPKA,PACSIN1,COBL |
| 2.733e-02 | -3.60 | response to estradiol | biological process | GO:0032355 | 117 | 19 | 16441 | 1675 |
GRN,CASP3,NQO1,CASP9,PDGFB,ETS1,SOCS3,CCND1,MMP15,NCOA3,CTGF,PTEN,MAP2,BMP7,CST3,CDKN1B,AURKA,IGFBP2,GPER1 |
| 2.737e-02 | -3.60 | haematopoietic_and_lymphoid_tissue-other-lymphangioma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-lymphangioma | 3 | 2 | 17775 | 1757 |
IDH1,PIK3CA |
| 2.737e-02 | -3.60 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-B_cell_prolymphocytic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-B_cell_prolymphocytic_leukaemia | 3 | 2 | 17775 | 1757 |
AKT1,TP53 |
| 2.737e-02 | -3.60 | central_nervous_system-spinal_cord-glioma-ependymoma_Grade_II | COSMIC cancer mutations | central_nervous_system-spinal_cord-glioma-ependymoma_Grade_II | 3 | 2 | 17775 | 1757 |
NF2,PTEN |
| 2.737e-02 | -3.60 | central_nervous_system-parietal_lobe-glioma-oligodendroglioma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-oligodendroglioma | 3 | 2 | 17775 | 1757 |
IDH1,TP53 |
| 2.737e-02 | -3.60 | central_nervous_system-spinal_cord-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-spinal_cord-glioma-ependymoma_Grade_III-IV | 3 | 2 | 17775 | 1757 |
NF2,PTEN |
| 2.737e-02 | -3.60 | peritoneum-carcinoma | COSMIC cancer mutations | peritoneum-carcinoma | 3 | 2 | 17775 | 1757 |
PTEN,PIK3CA |
| 2.737e-02 | -3.60 | central_nervous_system-parietal_lobe-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-gliosarcoma | 3 | 2 | 17775 | 1757 |
IDH1,PTEN |
| 2.737e-02 | -3.60 | central_nervous_system-frontal_lobe-glioma-astroblastoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astroblastoma_Grade_III | 3 | 2 | 17775 | 1757 |
IDH1,TP53 |
| 2.737e-02 | -3.60 | lymphangioma | COSMIC cancer mutations | lymphangioma | 3 | 2 | 17775 | 1757 |
IDH1,PIK3CA |
| 2.737e-02 | -3.60 | central_nervous_system-temporal_lobe-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-gliosarcoma | 3 | 2 | 17775 | 1757 |
IDH1,TP53 |
| 2.737e-02 | -3.60 | central_nervous_system-temporooccipital-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporooccipital-glioma-astrocytoma_Grade_IV | 3 | 2 | 17775 | 1757 |
IDH1,TP53 |
| 2.737e-02 | -3.60 | metatarsus | COSMIC cancer mutations | metatarsus | 3 | 2 | 17775 | 1757 |
GNAS,IDH1 |
| 2.737e-02 | -3.60 | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-cortisol_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-cortisol_producing | 3 | 2 | 17775 | 1757 |
GNAS,TP53 |
| 2.737e-02 | -3.60 | bone-tibia-chondrosarcoma-conventional | COSMIC cancer mutations | bone-tibia-chondrosarcoma-conventional | 3 | 2 | 17775 | 1757 |
IDH1,TP53 |
| 2.737e-02 | -3.60 | meninges-meningioma-angiomatous-microcystic | COSMIC cancer mutations | meninges-meningioma-angiomatous-microcystic | 3 | 2 | 17775 | 1757 |
NF2,AKT1 |
| 2.737e-02 | -3.60 | angiomatous-microcystic | COSMIC cancer mutations | angiomatous-microcystic | 3 | 2 | 17775 | 1757 |
NF2,AKT1 |
| 2.737e-02 | -3.60 | bone-femur-other-chondroma | COSMIC cancer mutations | bone-femur-other-chondroma | 3 | 2 | 17775 | 1757 |
GNAS,IDH1 |
| 2.737e-02 | -3.60 | central_nervous_system-medulla-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-medulla-glioma-gliosarcoma | 3 | 2 | 17775 | 1757 |
IDH1,PIK3CA |
| 2.737e-02 | -3.60 | central_nervous_system-frontotemporal-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontotemporal-glioma-oligodendroglioma_Grade_III | 3 | 2 | 17775 | 1757 |
CDKN2C,IDH1 |
| 2.737e-02 | -3.60 | vulva-carcinoma | COSMIC cancer mutations | vulva-carcinoma | 3 | 2 | 17775 | 1757 |
CDKN2C,TP53 |
| 2.737e-02 | -3.60 | oligoastrocytoma_Grade_IV | COSMIC cancer mutations | oligoastrocytoma_Grade_IV | 3 | 2 | 17775 | 1757 |
IDH1,PTEN |
| 2.737e-02 | -3.60 | B_cell_prolymphocytic_leukaemia | COSMIC cancer mutations | B_cell_prolymphocytic_leukaemia | 3 | 2 | 17775 | 1757 |
AKT1,TP53 |
| 2.737e-02 | -3.60 | central_nervous_system-parietal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-oligodendroglioma_Grade_II | 3 | 2 | 17775 | 1757 |
IDH1,PTEN |
| 2.737e-02 | -3.60 | meninges-meningioma-fibroblastic-transitional | COSMIC cancer mutations | meninges-meningioma-fibroblastic-transitional | 3 | 2 | 17775 | 1757 |
NF2,AKT1 |
| 2.737e-02 | -3.60 | stomach-other-metaplasia | COSMIC cancer mutations | stomach-other-metaplasia | 3 | 2 | 17775 | 1757 |
PTEN,TP53 |
| 2.737e-02 | -3.60 | fibroblastic-transitional | COSMIC cancer mutations | fibroblastic-transitional | 3 | 2 | 17775 | 1757 |
NF2,AKT1 |
| 2.737e-02 | -3.60 | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | MSigDB lists | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | 81 | 14 | 17758 | 1761 |
MAPKAPK2,SIGIRR,RPS6KA2,RIPK2,RPS6KA1,PELI2,NFKBIA,NOD2,MAPK11,PELI3,DUSP4,ELK1,FOS,CDK1 |
| 2.737e-02 | -3.60 | MICROTUBULE_BASED_PROCESS | MSigDB lists | MICROTUBULE_BASED_PROCESS | 81 | 14 | 17758 | 1761 |
ARHGEF10L,KIF5B,SUN2,AP1M2,MID1IP1,NF2,KIF13B,KIF23,TUBG1,NUSAP1,ARF6,KIF11,RASA1,CCDC88A |
| 2.737e-02 | -3.60 | TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | 81 | 14 | 17758 | 1761 |
GALNT3,B3GALNT1,UGT8,FUT2,A4GALT,MGAT4A,FUT8,MGAT4B,FUT1,GALNT7,POMGNT1,B4GALT4,B4GALNT1,GCNT1 |
| 2.738e-02 | -3.60 | RHO GTPases Activate ROCKs | REACTOME pathways | R-HSA-5627117 | 17 | 5 | 8202 | 867 |
MYL9,MYH14,RHOA,LIMK1,MYL12B |
| 2.738e-02 | -3.60 | CREB phosphorylation through the activation of CaMKII | REACTOME pathways | R-HSA-442729 | 17 | 5 | 8202 | 867 |
CALM3,CALM2,GRIN2D,CALM1,GRIN1 |
| 2.739e-02 | -3.60 | Hepatitis B | KEGG pathways | hsa05161 | 146 | 24 | 6908 | 758 |
DDX58,CCNE2,CASP3,DDB2,HSPG2,AKT1,STAT4,CASP9,PIK3R1,TP53,TGFBR1,ELK1,FOS,FAS,CCND1,JAK1,PTEN,NFKBIA,BAX,PIK3CA,CDKN1B,IRF7,PIK3CD,IFIH1 |
| 2.746e-02 | -3.60 | exocytosis | biological process | GO:0006887 | 314 | 43 | 16441 | 1675 |
ANXA3,CD63,HABP4,ARFGEF1,CALM3,SYTL4,PDGFB,SYTL2,PDGFA,CALM2,RAB15,CDK16,GATA2,LLGL2,RIMS3,STEAP2,EXOC8,CD9,CADPS2,PIK3CD,RAB27B,S100A13,SYK,SYTL3,MYO5A,RIMS2,RASGRP1,CHP1,LAMP2,RAB3B,CALM1,SCRIB,STX3,SCRN2,TRIM9,SERPINA1,RAB11FIP2,SYT7,NR4A3,RAB11FIP1,PLD1,SYT13,SNPH |
| 2.749e-02 | -3.59 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | 169 | 25 | 17758 | 1761 |
TGIF1,SERPINE2,CD82,RAPGEF2,COL4A5,MRAS,ATP1B1,SYTL2,HDAC9,EDNRA,PDGFA,TYMP,ITGB8,TRIM69,PASK,BCL6,DUSP10,SGK1,CDH3,EGFL7,IFIT1,ALPK1,MAST4,TMEM173,WBP5 |
| 2.750e-02 | -3.59 | ATPase dependent transmembrane transport complex | cellular component | GO:0098533 | 24 | 6 | 17570 | 1756 |
ATP1A1,ATP1B3,ATP1B1,GM2A,ABCD4,ABCA2 |
| 2.752e-02 | -3.59 | RasGEF | smart domains | SM00147 | 28 | 7 | 9131 | 997 |
BCAR3,RASGRF1,RALGPS2,RASGEF1A,RAPGEF2,RASGRP1,RASGRP2 |
| 2.754e-02 | -3.59 | Sestrin | interpro domains | IPR006730 | 3 | 2 | 18293 | 1814 |
SESN3,SESN1 |
| 2.754e-02 | -3.59 | Neuregulin_C | interpro domains | IPR002154 | 3 | 2 | 18293 | 1814 |
NRG2,NRG1 |
| 2.754e-02 | -3.59 | ETS_PEA3_N | interpro domains | IPR006715 | 3 | 2 | 18293 | 1814 |
ETV4,ETV5 |
| 2.754e-02 | -3.59 | ASD1_dom | interpro domains | IPR014800 | 3 | 2 | 18293 | 1814 |
SHROOM2,SHROOM3 |
| 2.754e-02 | -3.59 | Runx_central_dom | interpro domains | IPR027384 | 3 | 2 | 18293 | 1814 |
RUNX3,RUNX2 |
| 2.754e-02 | -3.59 | RIG-I_C-RD | interpro domains | IPR021673 | 3 | 2 | 18293 | 1814 |
DDX58,IFIH1 |
| 2.754e-02 | -3.59 | RGM_N | interpro domains | IPR010536 | 3 | 2 | 18293 | 1814 |
RGMB,RGMA |
| 2.754e-02 | -3.59 | Pyridine_nuc-diS_OxRdtase_2 | interpro domains | IPR000103 | 3 | 2 | 18293 | 1814 |
AIFM2,AIFM3 |
| 2.754e-02 | -3.59 | RGM_C | interpro domains | IPR009496 | 3 | 2 | 18293 | 1814 |
RGMB,RGMA |
| 2.754e-02 | -3.59 | Aldehyde_DH_NAD(P) | interpro domains | IPR012394 | 3 | 2 | 18293 | 1814 |
ALDH3B1,ALDH3A2 |
| 2.754e-02 | -3.59 | Pellino_fam | interpro domains | IPR006800 | 3 | 2 | 18293 | 1814 |
PELI3,PELI2 |
| 2.754e-02 | -3.59 | COR | interpro domains | IPR032171 | 3 | 2 | 18293 | 1814 |
LRRK1,DAPK1 |
| 2.754e-02 | -3.59 | 2oxoglutarate_DH_E1 | interpro domains | IPR011603 | 3 | 2 | 18293 | 1814 |
DHTKD1,OGDHL |
| 2.754e-02 | -3.59 | BMP_1/tolloid-like | interpro domains | IPR015446 | 3 | 2 | 18293 | 1814 |
BMP1,TLL2 |
| 2.754e-02 | -3.59 | LAMP_CS | interpro domains | IPR018134 | 3 | 2 | 18293 | 1814 |
LAMP2,LAMP1 |
| 2.754e-02 | -3.59 | Pro_4_hyd_alph_N | interpro domains | IPR013547 | 3 | 2 | 18293 | 1814 |
P4HA2,P4HA3 |
| 2.754e-02 | -3.59 | Sox_N | interpro domains | IPR022151 | 3 | 2 | 18293 | 1814 |
SOX8,SOX9 |
| 2.754e-02 | -3.59 | AhpD-like | interpro domains | IPR029032 | 3 | 2 | 18293 | 1814 |
SESN3,SESN1 |
| 2.754e-02 | -3.59 | UDPGP_trans_fam | interpro domains | IPR002618 | 3 | 2 | 18293 | 1814 |
UAP1,UGP2 |
| 2.754e-02 | -3.59 | AML1_Runt | interpro domains | IPR000040 | 3 | 2 | 18293 | 1814 |
RUNX3,RUNX2 |
| 2.754e-02 | -3.59 | OxRdtase_Mopterin_BS | interpro domains | IPR022407 | 3 | 2 | 18293 | 1814 |
AOX1,XDH |
| 2.754e-02 | -3.59 | Runt_dom | interpro domains | IPR013524 | 3 | 2 | 18293 | 1814 |
RUNX3,RUNX2 |
| 2.754e-02 | -3.59 | Procol_lys_dOase | interpro domains | IPR001006 | 3 | 2 | 18293 | 1814 |
PLOD3,PLOD2 |
| 2.754e-02 | -3.59 | Proteasome_activ_pa28_C | interpro domains | IPR003186 | 3 | 2 | 18293 | 1814 |
PSME1,PSME2 |
| 2.754e-02 | -3.59 | KGD_C | interpro domains | IPR031717 | 3 | 2 | 18293 | 1814 |
DHTKD1,OGDHL |
| 2.754e-02 | -3.59 | Popeye_prot | interpro domains | IPR006916 | 3 | 2 | 18293 | 1814 |
POPDC3,BVES |
| 2.754e-02 | -3.59 | SIPA1L_C | interpro domains | IPR021818 | 3 | 2 | 18293 | 1814 |
SIPA1L2,SIPA1L1 |
| 2.754e-02 | -3.59 | CITED | interpro domains | IPR007576 | 3 | 2 | 18293 | 1814 |
CITED2,CITED4 |
| 2.754e-02 | -3.59 | TMEM64/TMEM41 | interpro domains | IPR015414 | 3 | 2 | 18293 | 1814 |
TMEM64,TMEM41B |
| 2.754e-02 | -3.59 | SRC-1 | interpro domains | IPR014935 | 3 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 2.754e-02 | -3.59 | CARD_dom | interpro domains | IPR031964 | 3 | 2 | 18293 | 1814 |
DDX58,IFIH1 |
| 2.754e-02 | -3.59 | CDI | interpro domains | IPR003175 | 3 | 2 | 18293 | 1814 |
CDKN1B,CDKN1C |
| 2.754e-02 | -3.59 | Src1_rcpt_coact | interpro domains | IPR008955 | 3 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 2.754e-02 | -3.59 | 2Fe2S_fd_BS | interpro domains | IPR006058 | 3 | 2 | 18293 | 1814 |
AOX1,XDH |
| 2.754e-02 | -3.59 | RasGAP_C | interpro domains | IPR000593 | 3 | 2 | 18293 | 1814 |
IQGAP3,IQGAP1 |
| 2.754e-02 | -3.59 | AHD | interpro domains | IPR012966 | 3 | 2 | 18293 | 1814 |
RTKN2,ANLN |
| 2.754e-02 | -3.59 | RunxI_C_dom | interpro domains | IPR013711 | 3 | 2 | 18293 | 1814 |
RUNX3,RUNX2 |
| 2.754e-02 | -3.59 | DUF1518 | interpro domains | IPR010011 | 3 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 2.754e-02 | -3.59 | Nuc_rcpt_coact_Ncoa-typ | interpro domains | IPR014920 | 3 | 2 | 18293 | 1814 |
NCOA3,NCOA2 |
| 2.754e-02 | -3.59 | GlyclTrfase_18 | interpro domains | IPR026116 | 3 | 2 | 18293 | 1814 |
MGAT5B,MGAT5 |
| 2.754e-02 | -3.59 | Na/H_exchanger_6 | interpro domains | IPR002090 | 3 | 2 | 18293 | 1814 |
SLC9A6,SLC9A7 |
| 2.754e-02 | -3.59 | Glcci1/FAM117 | interpro domains | IPR026642 | 3 | 2 | 18293 | 1814 |
FAM117A,GLCCI1 |
| 2.754e-02 | -3.59 | Cadg | interpro domains | IPR006644 | 3 | 2 | 18293 | 1814 |
SGCE,DAG1 |
| 2.754e-02 | -3.59 | DUF4071 | interpro domains | IPR025136 | 3 | 2 | 18293 | 1814 |
MAP3K5,MAP3K6 |
| 2.754e-02 | -3.59 | C-myb_C | interpro domains | IPR015395 | 3 | 2 | 18293 | 1814 |
MYBL1,MYBL2 |
| 2.754e-02 | -3.59 | Proteasome_activ_pa28_N | interpro domains | IPR003185 | 3 | 2 | 18293 | 1814 |
PSME1,PSME2 |
| 2.754e-02 | -3.59 | Proteasome_activ_pa28 | interpro domains | IPR009077 | 3 | 2 | 18293 | 1814 |
PSME1,PSME2 |
| 2.754e-02 | -3.59 | TPM4 (tropomyosin 4) | protein interactions | 7171 | 61 | 12 | 16036 | 1726 |
SIRT1,PSMD1,ATP1A1,AKT1,CORO1C,TBCD,TP53,PRKCDBP,ARRB1,OSTF1,CENPE,PACSIN1 |
| 2.754e-02 | -3.59 | SLC9A3R2 (solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2) | protein interactions | 9351 | 61 | 12 | 16036 | 1726 |
SMARCA2,PTEN,PHLPP2,PIK3CA,SGK3,EZR,SGK1,NUSAP1,NPC2,PHLPP1,PRKACA,PLCB2 |
| 2.755e-02 | -3.59 | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | 194 | 28 | 17758 | 1761 |
SMARCA2,MBP,RHOA,ADD1,PIK3R1,ARL4C,SWI5,C5orf30,SELL,GLO1,BLVRA,YES1,ETS1,FOS,IL18R1,RABGGTA,SS18,KCNN4,ZFP36,STK38,FAM117A,SGK1,FAM102A,TAGLN2,PIK3CD,TRAM1,TOB1,GM2A |
| 2.755e-02 | -3.59 | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | 194 | 28 | 17758 | 1761 |
DOCK4,PGM1,TXN,IL15RA,SERPINE2,SH3BGRL,CTDSPL,UTRN,COL4A5,TGOLN2,BCL2L1,CCNF,CD40,DDR1,DNAJB9,TFAP4,ADD3,HNRNPH2,SPINT2,FAM102A,MDFIC,ATP1B3,ACSL4,MAP3K5,TRAF5,CKAP4,KDELR1,PCSK5 |
| 2.755e-02 | -3.59 | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP | 194 | 28 | 17758 | 1761 |
GRN,LAMP1,ENPP4,ANXA3,SPRED1,LPGAT1,IQGAP1,CUL4B,FAM102B,MCFD2,ARHGEF40,FAM46C,CRISPLD2,VPS26A,CD83,NIN,ATG4A,AKIRIN1,AP1AR,SS18,IGF1R,KBTBD2,KCNN4,LRIG1,KLF9,CTTN,ZMIZ1,CXorf56 |
| 2.755e-02 | -3.59 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 194 | 28 | 17758 | 1761 |
CD99,HES1,TIMP2,ZWINT,TXN,RHOA,MPP1,LYRM1,CDC20,MYBL2,GTF2A2,STIL,PSIP1,RHEB,KCTD9,VPS26A,IDE,ETS2,GDE1,PPP4R1,PGRMC1,PLK4,GOT1,RFX5,CENPE,FAIM,SCN3A,WBP5 |
| 2.755e-02 | -3.59 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 194 | 28 | 17758 | 1761 |
MX1,LOC81691,PGM1,LGALS3,IFITM3,CKAP2,SH3BGRL,CDC20,KIF23,NUSAP1,ANLN,MRPS36,CDK1,PDIA4,TOP2A,CDKN2AIPNL,CNTRL,DCK,SIVA1,PLK4,TUBG1,BUB1,STK39,CMPK2,CRTAP,ACOT7,S100A6,XDH |
| 2.755e-02 | -3.59 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 194 | 28 | 17758 | 1761 |
PLEKHA6,SORT1,CDK17,PAPSS2,SLC37A1,NFKBIE,LRRFIP2,SERPINE2,PLAUR,SAV1,CD40,PRDX4,OPTN,BTG3,TRANK1,C19orf66,MAP2,KBTBD2,RUNDC3B,ALPK3,RFX5,ECE1,CACNA1D,GLA,SNX10,AHR,CKS2,LAMP3 |
| 2.757e-02 | -3.59 | CACGTG_V$MYC_Q2 | MSigDB lists | CACGTG_V$MYC_Q2 | 976 | 115 | 17758 | 1761 |
LAMP1,PLA2G4A,LZTFL1,AVPI1,ARMCX3,IL15RA,HOXB7,TRIP10,CAMKK1,TESK2,VARS2,GRK6,MORF4L2,SNN,SDC1,SLC20A1,NUP62CL,CDKN2C,WEE1,ATP6V0B,PLCG2,ABCA2,BCL6,ANKRD12,SNX16,MANF,EPB41L4B,ARMCX6,DVL2,SIRT1,SNTB2,CBX6,DUSP4,C15orf39,MYL12A,ALDH3B1,WIPI1,NGFRAP1,HOXA9,KLF11,GLA,C1orf43,ARF6,AIFM3,E2F8,MAFF,ABCA1,HOXC13,IER5L,RUNX2,CPEB4,ALDH6A1,FAM134A,PKN1,BEX2,FGF19,EFNB1,HPCAL4,BMP2K,VPS26A,DNAJB9,PDIA4,WWP2,TFAP4,IGF1R,RNF128,ZNRF2,BHLHE41,BMP7,KCNN4,FAM13B,RANBP1,BAX,SORL1,SGK1,RFX5,TAGLN2,KLF9,CACNA1D,CITED2,CLIP2,CNPY3,SOCS5,B3GALT6,PHF20L1,PLEKHA6,HPS3,SHMT1,LONRF3,BCL9,SYBU,OGDHL,ELK1,TCEAL8,CDK5R1,RASGRP2,GNAS,ONECUT1,TIMM8A,HNRNPH2,KBTBD2,CGREF1,PRPS2,NR4A3,FAM117A,CTSA,HMGA1,ATP1B3,OSR1,UBE2C,RARG,RNF146,RAB3IL1,RUSC1,CXorf56 |
| 2.758e-02 | -3.59 | negative regulation of lipid metabolic process | biological process | GO:0045833 | 79 | 14 | 16441 | 1675 |
PDGFA,SIRT1,ACACB,ATP1A1,ADORA1,PPP2R5A,AKT1,SLC27A1,DAB2IP,GPER1,PDGFB,FGF19,PLIN5,GPLD1 |
| 2.758e-02 | -3.59 | fatty-acyl-CoA binding | molecular function | GO:0000062 | 30 | 7 | 16491 | 1673 |
ECI2,ACBD5,ACOX2,ACADSB,ALDH6A1,DBI,ACOT7 |
| 2.758e-02 | -3.59 | ADP binding | molecular function | GO:0043531 | 30 | 7 | 16491 | 1673 |
ATP1A1,PRKAG2,ADCK3,GCLC,PRPS2,ABCG1,TAP1 |
| 2.758e-02 | -3.59 | phospholipase C activity | molecular function | GO:0004629 | 30 | 7 | 16491 | 1673 |
PDIA3,PLCH1,PLCG1,ADORA1,PLCB2,PLCG2,EDNRA |
| 2.760e-02 | -3.59 | protein autophosphorylation | biological process | GO:0046777 | 189 | 28 | 16441 | 1675 |
MAP3K3,PINK1,AKT1,EPHA4,ERBB2,EIF2AK1,EPHA1,TEC,YES1,PRKACA,DDR1,STK17B,MAPKAPK2,DAPK2,JAK1,IGF1R,FGFR2,STK26,PASK,NEK2,DAPK1,MAP3K9,AURKA,EPHB4,PIM1,JAK3,SYK,MELK |
| 2.763e-02 | -3.59 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | 340 | 45 | 17758 | 1761 |
LAMP1,CCNI,GAA,SLC35D2,CPEB4,GNPDA1,ST14,HEXB,ASAH1,IL18,F11R,FAM21C,GNS,ZFYVE16,SESN3,ALG13,MGAT4A,AIM1,PAPSS1,SORL1,RCAN3,GM2A,MYO5A,TRAK2,PARP9,GCNT1,TIMP2,ALDH2,PLSCR1,ITCH,SAT1,TMEM144,PRKAR2B,LHFPL2,BBS2,ALCAM,ATP10D,SCARB2,PRCP,PLD1,TMEM159,LTA4H,IFIH1,RRAGD,TMEM131 |
| 2.768e-02 | -3.59 | extraskeletal | COSMIC cancer mutations | extraskeletal | 942 | 111 | 17775 | 1757 |
GAS2L1,SLC35D2,BCAM,NCKAP5,KIAA1462,CRYM,GALNT12,CCDC110,ATP2C2,RET,FHDC1,TP53,ERBB2,PKP2,ITPR2,PLXNA1,DDR1,DNER,PDGFA,SS18,CYP1A1,STIM1,STEAP2,PIK3CA,ANKRD12,PHKA2,TLN2,TSPAN1,TIAM1,MGAT5,NR2C1,NEB,SULF2,ZNF462,SPEF2,CELSR2,AKT1,PTPRU,SYNE2,UTRN,RGAG1,NUSAP1,TNS1,C15orf39,IDH1,DOCK5,COL12A1,ATP13A2,KDM4D,MAN2A2,MFAP3L,HS6ST1,WFS1,ATP7B,LRIG1,SIPA1L1,SECTM1,MADD,RAB11FIP1,OVOL1,UNC5B,ABCA1,SCN5A,ARHGEF3,CDK17,RUNX2,CHCHD7,TBC1D1,LRP4,DGKQ,SLC25A27,OSGIN2,NKRF,NTAN1,DNAH3,PARM1,TEAD3,AIM1L,FUT2,IGF1R,PTEN,LLGL2,MEGF8,KLF9,PIKFYVE,IQGAP3,DGKG,MED22,IGSF3,ERMAP,LONRF3,RC3H2,PIK3R1,GRIN1,ATP8B3,RNPEP,PLIN5,PRX,KLHL2,FECH,AP1AR,SWAP70,COQ10A,FGFR2,CGREF1,EGFL7,PLIN3,WDR62,TOB1,GOLGB1,JARID2 |
| 2.780e-02 | -3.58 | IGF1R (insulin-like growth factor 1 receptor) | protein interactions | 3480 | 75 | 14 | 16036 | 1726 |
IRS2,KCNIP3,IGF1R,JAK1,DOK4,PIK3R1,TP53,ARRB1,ERBB2,FBXO6,MAP3K5,RASA1,EHD1,SOCS3 |
| 2.785e-02 | -3.58 | FOS (FBJ murine osteosarcoma viral oncogene homolog) | protein interactions | 2353 | 126 | 21 | 16036 | 1726 |
SIRT1,PRKAA2,RUNX2,NQO1,TSC22D3,RPS6KA1,ELK1,PRKACA,FOS,ETS1,LMNA,OPTN,NCOA3,RPS6KA2,ETS2,CABP1,MITF,GTF2F2,USF2,MAFF,NCOA2 |
| 2.789e-02 | -3.58 | PCP/CE pathway | REACTOME pathways | R-HSA-4086400 | 91 | 16 | 8202 | 867 |
RHOA,PSMB4,FZD4,PSME2,PRICKLE1,PSMD10,SCRIB,PSME1,ROR1,PSMA4,FZD6,FZD7,PSMD1,RYK,FZD5,DVL2 |
| 2.793e-02 | -3.58 | MODULE_84 | MSigDB lists | MODULE_84 | 527 | 66 | 17758 | 1761 |
MYL9,HSPG2,S100A11,THRA,TSC22D3,TAP1,NRG2,IL27RA,SDC1,IER3,CCND1,TYMP,CDH1,LMO4,BCL6,IFIT1,LGMN,PTPRE,LAMP3,CYP1B1,MX1,COL6A2,TIMP2,S100A4,PLEKHO1,ARHGDIB,ITPR3,CCNF,STK17B,MDK,ENPP1,SECTM1,BMP1,NRGN,ABCA1,GRN,PARP12,PCOLCE,LGALS3,ITGA6,SELL,TRIB2,ADAMTSL4,DHRS3,SEPP1,TSPAN7,HLA-A,M6PR,CXCL16,CTSC,COL6A1,IGFBP2,CADPS2,C10orf54,HLA-C,PLSCR1,STAT4,RUNX3,TCF7,SERPINA1,SEMA4D,PVRL2,DHRS2,ITPR1,DEF6,RAB3IL1 |
| 2.795e-02 | -3.58 | ADENYL_RIBONUCLEOTIDE_BINDING | MSigDB lists | ADENYL_RIBONUCLEOTIDE_BINDING | 161 | 24 | 17758 | 1761 |
PINK1,PEX6,GCLC,ABCG2,TP53,TGFBR1,PIF1,MAP3K6,STK17B,DGKE,ABCD4,STK17A,DAPK2,ACVRL1,ATP7B,STK38,ABCA2,DAPK1,ABCB1,PIM1,MAP3K5,ABCC1,SEPHS1,ABCG1 |
| 2.795e-02 | -3.58 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | 161 | 24 | 17758 | 1761 |
ZNF462,LTBP1,DDB2,PDGFC,EPAS1,S100A11,MACC1,STAT4,LRRC66,FAM102B,SNTB1,C3orf18,NRP2,RNF128,ZCCHC12,SPINT2,PLK4,IGFBP2,DLG3,RAB27B,RBMS2,SCN3A,FAM69A,RRAGD |
| 2.795e-02 | -3.58 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | 161 | 24 | 17758 | 1761 |
GFPT1,SGCE,ADAMTS2,DEPDC1,GCLC,CAST,C1GALT1C1,SLC1A3,NTAN1,SESN1,CASP4,RHEB,B3GALNT1,PTEN,TMEM30A,P4HA2,LHX6,ATRNL1,TLE1,DIXDC1,KLF9,SEMA3G,NRGN,SCYL3 |
| 2.796e-02 | -3.58 | meiotic spindle | cellular component | GO:0072687 | 3 | 2 | 17570 | 1756 |
AURKA,ASPM |
| 2.796e-02 | -3.58 | microspike | cellular component | GO:0044393 | 3 | 2 | 17570 | 1756 |
EZR,PROM2 |
| 2.796e-02 | -3.58 | Schwann cell microvillus | cellular component | GO:0097454 | 3 | 2 | 17570 | 1756 |
AKR1B1,EZR |
| 2.796e-02 | -3.58 | TAP complex | cellular component | GO:0042825 | 3 | 2 | 17570 | 1756 |
TAPBP,TAP1 |
| 2.796e-02 | -3.58 | anchoring collagen complex | cellular component | GO:0030934 | 3 | 2 | 17570 | 1756 |
COL7A1,COL12A1 |
| 2.796e-02 | -3.58 | proteasome activator complex | cellular component | GO:0008537 | 3 | 2 | 17570 | 1756 |
PSME1,PSME2 |
| 2.796e-02 | -3.58 | endoplasmic reticulum Sec complex | cellular component | GO:0031205 | 3 | 2 | 17570 | 1756 |
SEC61B,DNAJC3 |
| 2.802e-02 | -3.57 | melatonin degradation I | BIOCYC pathways | HUMAN_PWY-6398 | 10 | 4 | 907 | 115 |
CYP2U1,POR,CYP2S1,CYP1B1 |
| 2.803e-02 | -3.57 | regulation of actin filament length | biological process | GO:0030832 | 133 | 21 | 16441 | 1675 |
SSH3,RHOA,SSH1,ADD1,FMN1,EPS8,ARFGEF1,SPTB,RASA1,PLEKHH2,SWAP70,DLG1,TRIOBP,SPTBN5,TMOD2,CTTN,ARF6,ARPC2,SHROOM2,F2RL1,NEB |
| 2.804e-02 | -3.57 | cellular response to oxidative stress | biological process | GO:0034599 | 173 | 26 | 16441 | 1675 |
PPIF,SIRT1,PRODH,SLC25A24,PINK1,NQO1,EPAS1,OXR1,ETV5,TP53,NFE2L1,SLC11A2,HDAC6,PRKRA,FOS,ETS1,ALDH3B1,DHRS2,CST3,AKR1B1,OSER1,NR4A2,MAP3K5,CPEB2,MELK,CYP1B1 |
| 2.806e-02 | -3.57 | lamellar body | cellular component | GO:0042599 | 18 | 5 | 17570 | 1756 |
LAMP1,KLK7,KLK5,CKAP4,LAMP3 |
| 2.810e-02 | -3.57 | human chr22q13.1-q13.2 | chromosome location | human chr22q13.1-q13.2 | 4 | 2 | 26250 | 1887 |
APOBEC3B,APOBEC3G |
| 2.810e-02 | -3.57 | human chr10q21-q22 | chromosome location | human chr10q21-q22 | 4 | 2 | 26250 | 1887 |
EIF4EBP2,ZWINT |
| 2.810e-02 | -3.57 | human chr2q35-q36 | chromosome location | human chr2q35-q36 | 4 | 2 | 26250 | 1887 |
TNS1,SCG2 |
| 2.815e-02 | -3.57 | positive regulation of cyclin-dependent protein kinase activity | biological process | GO:1904031 | 30 | 7 | 16441 | 1675 |
CCND1,PSMD10,PIM1,AKT1,PDGFB,STIL,RGCC |
| 2.816e-02 | -3.57 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | 186 | 27 | 17758 | 1761 |
PPIF,SLC37A1,NFKBIE,TNIP1,IL15RA,TRIP10,CD82,RC3H2,SDC4,SERTAD3,NFE2L1,EZR,ARFRP1,PLXNA1,BSDC1,NIN,KDM4D,IER3,BTG3,NFKBIA,SLC2A6,FJX1,RAP2C,RUNDC3B,CD70,HOOK1,EHD1 |
| 2.816e-02 | -3.57 | GSE3982_DC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_DC_VS_BASOPHIL_UP | 186 | 27 | 17758 | 1761 |
GRN,GAA,NQO1,GALNT12,MBNL3,DIAPH2,TNS1,SLC1A3,NANS,NTAN1,SLC20A1,MERTK,ALCAM,PPP2R3A,CD83,ARHGEF10L,CCDC92,SCARB2,DRAM1,CLIP4,TIAM1,NRGN,LTA4H,SPRY2,ACOT7,MCCC2,GM2A |
| 2.816e-02 | -3.57 | GSE360_L_MAJOR_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_T_GONDII_DC_DN | 186 | 27 | 17758 | 1761 |
SGCE,SLC25A24,CRYM,GCLC,HABP4,C5orf30,COL4A5,KCTD2,MERTK,IL18R1,SLC9A7,FANCI,PDIA4,WWP2,B4GALNT1,RASGRP2,DIRAS3,TAF1B,HOXA9,PEX2,PHTF1,MATN2,ERAP1,DIXDC1,GDF11,CACNA1D,ST3GAL1 |
| 2.816e-02 | -3.57 | GSE27786_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD4_TCELL_UP | 186 | 27 | 17758 | 1761 |
SYPL1,HES1,RHOA,IL15,LPGAT1,STAU2,ITPR3,OAT,NPHP3,IDH1,NUBP1,DCP2,HMGXB4,SAC3D1,ATP6V0B,TNS3,GALNS,CST3,YOD1,ICOSLG,TRAF5,CDKN2D,ST3GAL1,DDX59,CKAP4,MYO5A,JARID2 |
| 2.816e-02 | -3.57 | GSE7852_LN_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_UP | 186 | 27 | 17758 | 1761 |
GAA,MRPS33,BCL9,USP18,STRADB,MPP5,ERBB2IP,MGST2,SNN,SESN1,DENND2D,DCP2,XKRX,TFAP4,MAMDC4,SESN3,MGAT4A,DLG1,SGK3,TRIM21,ARRB1,HMGA1,CEP41,PIKFYVE,MAST4,NR2C1,ISOC1 |
| 2.816e-02 | -3.57 | GSE3982_BASOPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_BASOPHIL_VS_NKCELL_DN | 186 | 27 | 17758 | 1761 |
ENPP4,RASGRF1,SIGIRR,KCNJ12,CELSR2,TESK1,GGA1,KLK6,BLVRA,LDB2,LTBP3,OPTN,PRIM1,SGPL1,ENDOD1,GABRD,PLEKHG6,NEIL1,CTSC,P4HA2,PRPS2,ATRNL1,EFNA5,LTA4H,TMEM14A,MCCC2,FARP2 |
| 2.820e-02 | -3.57 | CELL_MIGRATION | MSigDB lists | CELL_MIGRATION | 89 | 15 | 17758 | 1761 |
DPYSL5,ARAP3,NF2,PTEN,ACVRL1,SCG2,BCAR1,SHROOM2,S100A2,SYK,CCDC88A,CDK5R1,NRP2,PARP9,SEMA3B |
| 2.820e-02 | -3.57 | Nucleotide-diphossugar_trans | interpro domains | IPR029044 | 89 | 15 | 18293 | 1814 |
CHSY3,GALNT3,CMAS,UAP1,UGP2,PLOD2,A4GALT,GALNT12,GYLTL1B,GALNT7,PLOD3,POMGNT1,B4GALT4,GLT8D2,B4GALNT1 |
| 2.826e-02 | -3.57 | regulation of nuclear division | biological process | GO:0051783 | 157 | 24 | 16441 | 1675 |
PLK1,DLGAP5,CIT,PTTG1,CDC20,RGCC,NUSAP1,PKMYT1,ANLN,PDGFB,KIF11,BORA,RPS6KA2,IGF1R,FGFR2,PTEN,BMP7,CDCA5,NEK2,AURKA,BUB1,CENPE,UBE2C,ESPL1 |
| 2.827e-02 | -3.57 | protein localization to plasma membrane | biological process | GO:0072659 | 149 | 23 | 16441 | 1675 |
KCNIP3,RAB3B,TSPAN15,CRB3,RAPGEF2,PKP2,EZR,MPP5,ARFRP1,F11R,KIF13A,ATP1B1,EMP2,BBS2,OPTN,RAB15,CDH1,DLG1,ZDHHC23,PLEKHF1,ATP1B3,PACSIN1,MYO5A |
| 2.830e-02 | -3.56 | RasGEF | pfam domains | PF00617 | 30 | 7 | 16629 | 1696 |
BCAR3,RASGRF1,RASGEF1A,RALGPS2,RAPGEF2,RASGRP1,RASGRP2 |
| 2.833e-02 | -3.56 | human chr4q24 | chromosome location | human chr4q24 | 33 | 6 | 26250 | 1887 |
CXXC4,BANK1,NPNT,SLC39A8,DDIT4L,PAPSS1 |
| 2.838e-02 | -3.56 | regulation of extent of cell growth | biological process | GO:0061387 | 102 | 17 | 16441 | 1675 |
SEMA6B,PLXNA1,CRABP2,CDK5R1,SEMA4D,DPYSL2,MEGF8,LIMK1,TNFRSF12A,EFNA5,NRG1,SEMA3G,CTTN,WNT3A,SEMA3A,L1CAM,SEMA3B |
| 2.843e-02 | -3.56 | ANATOMICAL_STRUCTURE_MORPHOGENESIS | MSigDB lists | ANATOMICAL_STRUCTURE_MORPHOGENESIS | 367 | 48 | 17758 | 1761 |
GAA,GCLM,ARAP3,SSH1,COL18A1,AES,IL18,NRP2,ELF3,SCML1,IER3,CYR61,LMO4,DLG1,BAX,CD9,TWIST1,EPHB4,NOTCH3,RCAN3,F2R,ETV7,SPRY2,SYK,CCDC88A,SEMA3B,DPYSL5,GCLC,NFE2L1,HTATIP2,CDK5R1,RASA1,SOX13,PITX2,KCNMB4,SCG2,COL13A1,SHROOM3,ACVRL1,FGD6,ERAP1,TLE1,EGFL7,FZD5,ARF6,SHROOM2,HOXC13,FGD1 |
| 2.845e-02 | -3.56 | regulation of cellular metabolic process | biological process | GO:0031323 | 5773 | 624 | 16441 | 1675 |
ACACB,DNAJC3,HEXB,RET,FBXO2,NRG2,IL18,MORF4L2,BARD1,CARD10,GRM5,ZNF275,CALM2,CDKN2C,DAPK2,PSMD1,KLF3,CRY2,APOBEC3G,SMARCA2,TNIP1,CDA,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,HSPB1,E2F8,GAB1,HOXC13,NUAK1,ITGA6,SOX9,RAB23,LMNA,ELF3,TFAP4,PAIP2B,MEGF8,NEK2,MAP3K9,MYDGF,NCAM1,MYLIP,NUP85,PPP6R1,SALL4,STAT4,PYM1,MYBL2,ELK1,NPHP3,TP53INP2,PSMA4,PLIN5,STK17A,NCOA3,ETS2,SEMA4D,SETD3,AURKA,STK39,GDF11,SERPINB1,ZNF502,TMEM173,XDH,EGLN1,GRHL2,NQO1,INPP5D,ACTR8,PTTG1,PRKACA,CCND1,ST5,CDH1,SP100,DACT1,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,CAMSAP3,RIPK2,APOBEC3D,FZD4,HTATIP2,CDCA2,GTF2A2,SNX12,ZNF618,NFIX,IRS2,CORO1C,WFS1,RGS14,MAPK12,TNRC6C,NKX3-1,CKAP2,ESRP1,SDC4,HABP4,PKN1,ETS1,GSTP1,SRPX2,TIPRL,HOXB2,NEO1,CTNNBIP1,DIRAS3,CTSC,CST3,BAX,PLEKHF1,TMBIM6,WWP1,MAPK11,MED22,CRTAP,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,PITX2,ACVRL1,NR1D2,NR4A3,ITGAV,HMGA1,CENPE,OSR1,USF2,SIGIRR,EPAS1,CNOT8,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,SPTB,FANCI,RPS6KA2,NPNT,SHC3,IL6ST,ELF5,PASK,MITF,ABCA2,DUSP10,MYBL1,ZNF462,PLK1,THRB,PCGF5,CD55,KCNIP3,CELSR2,CITED4,CBX6,NFE2L1,EZR,IDH1,ZBTB7B,CDK1,OPTN,KDM4D,KLF12,HOXA9,ZNF367,PRKCDBP,KLF11,MAFF,RRAGD,PRKAA2,RUNX2,LMTK3,DNAJB2,RASA2,UBASH3B,PDCL,HES2,FBLN1,DAZAP1,IGF1R,GATA2,MDFIC,PIM1,WNT3A,RGMB,ZNF320,STRADB,SCRIB,EIF2AK1,TCF7,PDK3,CDK5R1,FOXD2,MAPKAPK2,CSF1,NLRC5,IFI6,USP43,AVPI1,NF2,HOXB7,UPF3B,FOXM1,CTDSPL,TP53,ERBB2,LPIN3,EMP2,STIL,BCAP31,SYTL2,IER3,RAD23A,TTC21B,PDGFA,LMO4,PLCG2,LHX6,BCL6,CDH3,NOTCH3,OAS3,EGLN3,CTDSP2,DVL2,CTH,SIRT1,PPIF,CLCN3,TIMP2,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,RBL1,STK38,EFNA5,IRF7,ZNF701,ARFGEF3,PINK1,CPEB4,MACC1,CD63,DAP,PSMD10,GTF3A,GDF15,HMGN3,NKRF,CRABP2,AIP,PARM1,SH2D4A,FZD6,PPP2R3A,CD109,FOXP2,GTF2F2,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,KLF9,SYK,TLE6,WBP5,NFE2L3,HES1,FBLN5,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,MAPK8IP1,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,PPP2R3C,NDFIP1,UBE2C,HIPK3,ZBTB33,PKIA,PPP4R4,TXN,LGR4,SSH1,TSC22D3,PSME1,CAMK1D,CCNB1,ZNF823,CTGF,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,ZBTB18,ACVR1C,PBK,CASP9,AGO4,PIF1,SAV1,LDB2,POR,AHRR,HLF,PLK2,PRDM5,EIF4EBP2,NFKBIZ,SERPINI1,F2RL1,TRAF5,LZTS1,DDX58,SCOC,CDKN1C,DGKQ,PSIP1,MECOM,CYR61,BHLHE41,DAPK1,SORL1,PIKFYVE,GPR161,TRAK2,SOCS5,MMD,ZNF84,MFI2,CALM1,PIP4K2C,NPC2,EPHA1,NFIB,RASA1,FAS,AP1AR,PRKAG2,PELI2,TCEAL4,FAM83D,SFMBT1,NR4A2,PER3,MAP3K5,SPRED1,FOXO6,DLGAP5,ARMCX3,S100A11,THRA,RPS6KA1,IQGAP1,CAST,BCL2L1,APLP2,ZNF75D,CDKN1B,DAB2IP,PDE4D,MED30,NR2C1,FOXJ2,DRAP1,PRKCQ,SLC11A2,PKMYT1,PYGO1,RAD17,H2AFV,SP4,FZD7,ZNF469,PRDM11,PPP2R5A,JAK1,STK26,NGFRAP1,SLC27A1,NRG1,KLF5,NR3C2,CBX7,PCOLCE,DEPDC1,HERC5,PBX3,APOBEC3H,FGF19,TEAD3,SIX4,SCML1,WWP2,SNTA1,E2F7,RNF128,PTEN,SGK3,DRAM1,ATP8B1,ERBB3,CNOT6L,CITED2,TRIM62,SPRY2,NCOA2,PDGFC,TGIF1,RASGRF1,FURIN,ZKSCAN2,YES1,FOS,GPLD1,CDK5RAP1,TIMP3,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,CPEB2,ESPL1,JARID2,RGMA,EMX1,CASP3,CRYM,CAMKK1,VARS2,ERP29,EPCAM,ZFYVE16,HSF2,GRHL1,ZCCHC12,SIVA1,PHTF1,DLG1,CTTN,SLC39A10,RASGRP1,SP5,CYP1B1,TRIM8,ASCL5,USP18,ITCH,TYSND1,EDNRA,MDK,NEIL1,ZNF114,GPRC5B,MADD,ZNF165,CAB39,SP6,ADIPOR1,GLA,NR2C2,PIFO,ZNF395,SERPINE2,PPP1R2,BVES,ETV5,CALM3,TEC,PHLPP1,ZNF432,C10orf54,RFX5,LRIF1,ETV7,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,RANBP9,SOX13,FECH,GNAS,BCAR3,ONECUT1,NUDT16,PLPP3,NFKBIA,SH3BP4,CTSA,JAK3,RARG,TOB1,PROM2,KLF7,CCNE2,SORBS1,IL15,PSME2,HDAC11,IL27RA,OSR2,SS18,SVBP,ZNF687,SETDB2,FRYL,KIF14,TWIST1,ECE1,F2R,FRS3,CHP1,CKS2,MAP3K3,ZNF525,GLO1,ERBB2IP,DUSP4,CD40,MAP3K6,SOCS3,ARHGAP35,JADE1,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,PPP2R2D,ABCA1,GLIS3,ANXA3,ARHGEF11,LRP4,MIER3,AES,TGFBR1,TRIB2,HMGXB4,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,ADORA1,MYCL,BMP7,TOX2,IQGAP3,NR4A1,GCLC,RGCC,MBNL3,RUNX3,TCEAL8,LEPR,FOXL1,SWAP70,PRCP,RAP2C,SPINT2,ARRB1,HOXB13,ZMIZ1,SOX8,AHR,ABCG1 |
| 2.853e-02 | -3.56 | Gastric acid secretion | KEGG pathways | ko04971 | 74 | 14 | 6908 | 758 |
GNAS,CALM2,ATP1A1,CA2,ITPR1,CALM1,EZR,CALM3,ATP1B3,ITPR2,ATP1B1,ITPR3,PLCB2,PRKACA |
| 2.853e-02 | -3.56 | Gastric acid secretion | KEGG pathways | hsa04971 | 74 | 14 | 6908 | 758 |
GNAS,CALM2,ATP1A1,CA2,ITPR1,CALM1,EZR,CALM3,ATP1B3,ITPR2,ATP1B1,ITPR3,PLCB2,PRKACA |
| 2.855e-02 | -3.56 | HEMATOPO_REC_L_F2 | prosite domains | PS01353 | 7 | 3 | 11866 | 1235 |
LEPR,LIFR,IL6ST |
| 2.855e-02 | -3.56 | GOLOCO | prosite domains | PS50877 | 7 | 3 | 11866 | 1235 |
GPSM2,RGS14,RAP1GAP |
| 2.855e-02 | -3.56 | PI3K_RBD | prosite domains | PS51546 | 7 | 3 | 11866 | 1235 |
PIK3C2B,PIK3CD,PIK3CA |
| 2.855e-02 | -3.56 | GS | prosite domains | PS51256 | 7 | 3 | 11866 | 1235 |
TGFBR1,ACVR1C,ACVRL1 |
| 2.855e-02 | -3.56 | PDGF_1 | prosite domains | PS00249 | 7 | 3 | 11866 | 1235 |
PDGFA,PGF,PDGFB |
| 2.855e-02 | -3.56 | ACB_2 | prosite domains | PS51228 | 7 | 3 | 11866 | 1235 |
ACBD5,ECI2,DBI |
| 2.857e-02 | -3.56 | WONG_EMBRYONIC_STEM_CELL_CORE | MSigDB lists | WONG_EMBRYONIC_STEM_CELL_CORE | 332 | 44 | 17758 | 1761 |
DLGAP5,CDKN1C,GNPDA1,CKAP2,NDC80,CDCA8,TP53,KIF23,CRABP2,ERP29,PDIA4,CCND1,TOP2A,SS18,WEE1,CTSC,NEK2,BAX,PLK4,BUB1,ALDH7A1,CKS2,PLK1,AMOTL2,TGIF1,KIF20A,CDC20,MYBL2,AK4,GLO1,NUSAP1,CCNF,MRPS36,SLC25A5,KIF11,CDK1,PRIM1,MID1IP1,TIMM8A,CDCA5,HDAC1,AURKA,MRPS28,CCNB2 |
| 2.860e-02 | -3.55 | Znf_RING/FYVE/PHD | interpro domains | IPR013083 | 438 | 56 | 18293 | 1814 |
EXPH5,RMND5A,RNF224,TRIM2,RNF182,SYTL4,PJA2,HDAC6,BARD1,TRIM68,ZFYVE9,SYTL2,ZFYVE16,MARCH8,DTX3L,RNF220,MLPH,RNF128,PHF7,SP100,ZNRF2,MKRN3,TRIM21,PLEKHF1,MARCH2,PIKFYVE,RNF26,MYRIP,MYLIP,TRIM62,SYTL3,RIMS2,PHF20L1,PCGF5,TRIM8,ING1,LONRF3,AMFR,RC3H2,RNF113A,PYGO1,NEURL1B,JADE2,RNF19B,G2E3,JADE1,TRIM9,TRIM69,PEX2,DTX4,FGD6,FHL1,ZMIZ1,TRAF5,RNF146,FGD1 |
| 2.860e-02 | -3.55 | negative regulation of cell development | biological process | GO:0010721 | 281 | 39 | 16441 | 1675 |
SEMA6B,ADGRG1,CIT,SOX9,EPHA4,LRP4,TP53,FAM101B,FBLN1,PTEN,BMP7,VASN,KIAA0319,DUSP10,SORL1,DAB2IP,DIXDC1,TACSTD2,SEMA3G,NOTCH3,WNT3A,TRIM62,SEMA3B,HES1,RHOA,MFI2,RAPGEF2,ASPM,CDK5R1,DPYSL3,AP1AR,SEMA4D,PLK2,CORO1C,NRG1,GDF11,ARF6,SOX8,SEMA3A |
| 2.865e-02 | -3.55 | PLCG1 (phospholipase C, gamma 1) | protein interactions | 5335 | 149 | 24 | 16036 | 1726 |
GAS2L1,RHOA,AKT1,INPP5D,RET,GRIN1,ERBB2,TEC,MVB12B,DDR1,TIPRL,RASA1,IRS2,PDGFA,PTPRJ,JAK1,FGFR2,AXL,PITPNA,ERBB3,NCAM1,LIFR,GAB1,SYK |
| 2.870e-02 | -3.55 | Laminin interactions | REACTOME pathways | R-HSA-3000157 | 23 | 6 | 8202 | 867 |
COL18A1,ITGAV,ITGA3,HSPG2,ITGA7,ITGA6 |
| 2.871e-02 | -3.55 | HUANG_GATA2_TARGETS_UP | MSigDB lists | HUANG_GATA2_TARGETS_UP | 145 | 22 | 17758 | 1761 |
TGIF1,HLA-E,DAP,SAT1,KCTD12,TGFBR1,RAB38,MGST2,SH3KBP1,CMTM7,GABARAPL1,KCNN4,CST3,SLC2A6,FUT8,SIPA1L1,CDKN1B,FAM117A,DGKG,MYL12B,GAB1,TPCN1 |
| 2.872e-02 | -3.55 | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | 220 | 31 | 17758 | 1761 |
CASP3,TGIF1,UGP2,TRIP10,TESK1,NUAK1,TSC22D3,HSPA12A,PARP4,CDA,BTN3A1,SESN1,CASP4,STEAP1,TEAD3,CNTNAP1,MAN2A2,ADD3,SP100,EFR3A,CSF1,GALNS,BCL6,PRKG1,CSTF2,KLF5,NRG1,CNPY3,HIPK3,CYBRD1,CYP1B1 |
| 2.872e-02 | -3.55 | regulation of phospholipase C activity | biological process | GO:1900274 | 72 | 13 | 16441 | 1675 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,RASGRP1,EDNRA |
| 2.873e-02 | -3.55 | Deactivation of the beta-catenin transactivating complex | REACTOME pathways | R-HSA-3769402 | 42 | 9 | 8202 | 867 |
CTNNBIP1,AKT1,BCL9,SOX9,TLE1,HDAC1,TCF7,PYGO1,SOX13 |
| 2.873e-02 | -3.55 | Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | REACTOME pathways | R-HSA-381676 | 42 | 9 | 8202 | 867 |
GNAS,GNB5,IQGAP1,ITPR1,KCNS3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 2.875e-02 | -3.55 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 178 | 26 | 17758 | 1761 |
FADS2,MBP,CD55,RPS6KA1,S100A4,CD82,ITGA6,XYLT1,RUNX3,C15orf39,KBTBD11,TEAD3,CCND1,PLCH1,TIMP3,GATA2,CSF1,NOD2,DUSP10,IGFBP2,RGS14,E2F8,TPCN1,CKAP4,CYP1B1,CD33 |
| 2.875e-02 | -3.55 | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | 178 | 26 | 17758 | 1761 |
SIGIRR,FAM169A,ADD1,TSC22D3,SYNE2,BTN3A2,TCF7,ETS1,STK17B,LTBP3,KLF12,PASK,INPP4B,FAM117A,NR4A2,KLF9,EPHB4,PDE4D,SLC25A38,TBC1D4,HOOK1,MYLIP,PKIA,SNPH,DOCK9,EHD1 |
| 2.875e-02 | -3.55 | FERNANDEZ_BOUND_BY_MYC | MSigDB lists | FERNANDEZ_BOUND_BY_MYC | 178 | 26 | 17758 | 1761 |
PLA2G4A,SLC2A4,ALDH2,TXN,FOXM1,CD63,THRA,ITGA6,CASP9,EIF5A2,MYBL2,CR2,TGFBR1,ELK1,GSTP1,LBR,ARF4,LMNA,FECH,MAN2A2,ETS2,PTEN,DCK,BAX,FUT1,IRF2 |
| 2.875e-02 | -3.55 | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP | MSigDB lists | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP | 178 | 26 | 17758 | 1761 |
BIN1,PDGFC,PCOLCE,DLGAP5,ATP8A1,XYLT1,PLEKHO1,DUSP4,ZFAND5,DGKH,AHRR,EPCAM,FRY,PTEN,ABHD12,SPIN4,IQCE,PELI2,SECTM1,HDAC1,DONSON,PDE4D,RCAN3,TIPARP,MAFF,CYP1B1 |
| 2.877e-02 | -3.55 | phosphatidylcholine transporter activity | molecular function | GO:0008525 | 3 | 2 | 16491 | 1673 |
PITPNA,PCTP |
| 2.877e-02 | -3.55 | N-acetylglucosamine-6-sulfatase activity | molecular function | GO:0008449 | 3 | 2 | 16491 | 1673 |
GNS,SULF2 |
| 2.877e-02 | -3.55 | anaphase-promoting complex binding | molecular function | GO:0010997 | 3 | 2 | 16491 | 1673 |
PLK1,PTEN |
| 2.877e-02 | -3.55 | xenobiotic-transporting ATPase activity | molecular function | GO:0008559 | 3 | 2 | 16491 | 1673 |
ABCG2,ABCB1 |
| 2.877e-02 | -3.55 | procollagen-lysine 5-dioxygenase activity | molecular function | GO:0008475 | 3 | 2 | 16491 | 1673 |
PLOD3,PLOD2 |
| 2.877e-02 | -3.55 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity | molecular function | GO:0030144 | 3 | 2 | 16491 | 1673 |
MGAT5B,MGAT5 |
| 2.877e-02 | -3.55 | retinoic acid 4-hydroxylase activity | molecular function | GO:0008401 | 3 | 2 | 16491 | 1673 |
CYP26B1,CYP26A1 |
| 2.877e-02 | -3.55 | protein xylosyltransferase activity | molecular function | GO:0030158 | 3 | 2 | 16491 | 1673 |
XYLT2,XYLT1 |
| 2.877e-02 | -3.55 | beta-glucuronidase activity | molecular function | GO:0004566 | 3 | 2 | 16491 | 1673 |
HPSE,GUSB |
| 2.877e-02 | -3.55 | extracellular matrix protein binding | molecular function | GO:1990430 | 3 | 2 | 16491 | 1673 |
ITGAV,ITGB8 |
| 2.877e-02 | -3.55 | ferric-chelate reductase activity | molecular function | GO:0000293 | 3 | 2 | 16491 | 1673 |
CYB561,CYBRD1 |
| 2.877e-02 | -3.55 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | molecular function | GO:0008454 | 3 | 2 | 16491 | 1673 |
MGAT4A,MGAT4B |
| 2.877e-02 | -3.55 | iron-responsive element binding | molecular function | GO:0030350 | 3 | 2 | 16491 | 1673 |
FECH,ACO1 |
| 2.877e-02 | -3.55 | long-chain fatty acyl-CoA binding | molecular function | GO:0036042 | 3 | 2 | 16491 | 1673 |
DBI,ACOT7 |
| 2.877e-02 | -3.55 | oncostatin-M receptor activity | molecular function | GO:0004924 | 3 | 2 | 16491 | 1673 |
LIFR,IL6ST |
| 2.877e-02 | -3.55 | deoxycytidine deaminase activity | molecular function | GO:0047844 | 3 | 2 | 16491 | 1673 |
APOBEC3B,APOBEC3G |
| 2.878e-02 | -3.55 | salivary_gland-mouth_floor-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-mouth_floor-carcinoma-adenoid_cystic_carcinoma | 31 | 7 | 17775 | 1757 |
FGFR2,PTEN,THRA,CENPI,SYNE2,MELK,PIK3CA |
| 2.878e-02 | -3.55 | retroperitoneum | COSMIC cancer mutations | retroperitoneum | 31 | 7 | 17775 | 1757 |
ERBB2,AKT1,IDH1,FGFR2,RET,PIK3R1,PIK3CA |
| 2.879e-02 | -3.55 | MODULE_337 | MSigDB lists | MODULE_337 | 59 | 11 | 17758 | 1761 |
ARHGAP11A,SPEF2,MDM1,KCNN4,PRPS2,PLK4,DONSON,CD70,GPSM2,SAC3D1,IER3 |
| 2.879e-02 | -3.55 | RASHI_RESPONSE_TO_IONIZING_RADIATION_4 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_4 | 59 | 11 | 17758 | 1761 |
PSMB4,SP100,SEMA4D,PLK4,IL27RA,IFIT3,CA8,LIFR,FOXL1,E2F8,MED22 |
| 2.881e-02 | -3.55 | WANG_MLL_TARGETS | MSigDB lists | WANG_MLL_TARGETS | 280 | 38 | 17758 | 1761 |
MRC2,UGP2,IGFBP6,GALNT12,CCDC68,NOTUM,SLC7A2,OSR2,SEPP1,DHRS3,LGALS3BP,HDAC9,CDKN2C,APOBEC3B,CYP2S1,COL6A1,TMEM51,ANO4,MYLIP,ATP2B1,COL6A2,ALDH2,CYS1,ARHGDIB,FNDC3A,GLT8D2,PITX2,ENPP1,HLF,PELI2,CLIP4,NR4A2,MAP3K5,SLC27A3,PTGES,DEF6,RAB3IL1,HOXC13 |
| 2.887e-02 | -3.55 | shoulder | COSMIC cancer mutations | shoulder | 404 | 52 | 17775 | 1757 |
EXPH5,ARHGAP11A,ILDR1,MRC2,UGT8,FRMD4A,MACC1,LRP4,RASSF7,TP53,LMNA,HLA-A,MECOM,KIF5B,SNTA1,MDM1,PTEN,MITF,PIK3CA,SGK1,PIK3CD,LMAN1,PTPRE,MYO5A,ADAMTS2,SUN2,AKT1,PIK3R1,LRRC66,TNS1,COL7A1,IDH1,NUBP1,FANCE,FOXL1,GNA11,ATP13A2,PTPRF,EPHA10,DUOX1,PLCH1,PLEKHG6,BANK1,PTPRJ,PLEKHH2,PTK7,SLC4A3,ALPK3,CSTF2,PER3,HIPK3,COBL |
| 2.895e-02 | -3.54 | EGF_CA | pfam domains | PF07645 | 72 | 13 | 16629 | 1696 |
LTBP1,FBLN5,FAT4,NPNT,MEGF8,MATN2,BMP1,EGFL7,LTBP2,NOTCH3,FBLN1,LTBP3,TLL2 |
| 2.896e-02 | -3.54 | regulation of DNA binding | biological process | GO:0051101 | 87 | 15 | 16441 | 1675 |
ZNF462,CTNNBIP1,TFAP4,HES1,TXN,SP100,HJURP,PLAUR,NFKBIA,HABP4,NEK2,PPARA,TWIST1,NFIB,MDFI |
| 2.897e-02 | -3.54 | channel regulator activity | molecular function | GO:0016247 | 134 | 21 | 16491 | 1673 |
KCNIP3,CCDC109B,FXYD3,CACNA2D2,PKP2,HPCAL4,RASA1,GPLD1,PIAS3,SNTA1,KCNMB4,STIM1,ITPR1,DLG1,SGK3,KCNS3,PRKG1,FXYD5,SGK1,TSPAN13,CHP1 |
| 2.901e-02 | -3.54 | myeloid cell differentiation | biological process | GO:0030099 | 198 | 29 | 16441 | 1675 |
CASP3,ADD1,CDKN1C,HOXB7,EPAS1,OSTM1,THRA,CASP9,NFE2L1,SLC11A2,EIF2AK1,GLO1,TNFSF9,CD109,FECH,GATA2,DHRS2,CSF1,MITF,IL31RA,BCL6,PTBP3,PIK3CD,LRRK1,JAK3,SNX10,F2RL1,SLC25A38,FARP2 |
| 2.901e-02 | -3.54 | gonad development | biological process | GO:0008406 | 198 | 29 | 16441 | 1675 |
SIRT1,REC8,COL9A3,NKX3-1,FZD4,ASPM,CENPI,SOX9,TFAP2C,TGFBR1,BCL2L1,FNDC3A,IDH1,SDC1,SIX4,PRDX4,SGPL1,CCND1,PITX2,LRRC6,HOXA9,CTSV,CST3,TOX2,BAX,ARRB1,OSR1,SOX8,TIPARP |
| 2.901e-02 | -3.54 | interferon-beta production | biological process | GO:0032608 | 3 | 2 | 16441 | 1675 |
IRF7,TMEM173 |
| 2.901e-02 | -3.54 | MDA-5 signaling pathway | biological process | GO:0039530 | 3 | 2 | 16441 | 1675 |
IRF7,IFIH1 |
| 2.901e-02 | -3.54 | negative regulation of cardiac muscle contraction | biological process | GO:0055118 | 3 | 2 | 16441 | 1675 |
PDE5A,ADORA1 |
| 2.901e-02 | -3.54 | kinin cascade | biological process | GO:0002254 | 3 | 2 | 16441 | 1675 |
F12,PRCP |
| 2.901e-02 | -3.54 | protein localization to cell cortex | biological process | GO:0072697 | 3 | 2 | 16441 | 1675 |
EZR,NUBP1 |
| 2.901e-02 | -3.54 | fasciculation of sensory neuron axon | biological process | GO:0097155 | 3 | 2 | 16441 | 1675 |
MEGF8,EPHA4 |
| 2.901e-02 | -3.54 | beta selection | biological process | GO:0043366 | 3 | 2 | 16441 | 1675 |
RHOA,SYK |
| 2.901e-02 | -3.54 | response to iron(III) ion | biological process | GO:0010041 | 3 | 2 | 16441 | 1675 |
CYP1A1,CCNB1 |
| 2.901e-02 | -3.54 | plasma kallikrein-kinin cascade | biological process | GO:0002353 | 3 | 2 | 16441 | 1675 |
F12,PRCP |
| 2.901e-02 | -3.54 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death | biological process | GO:1902445 | 3 | 2 | 16441 | 1675 |
PPIF,BAX |
| 2.901e-02 | -3.54 | malate-aspartate shuttle | biological process | GO:0043490 | 3 | 2 | 16441 | 1675 |
SLC1A3,SLC25A13 |
| 2.901e-02 | -3.54 | negative regulation of nuclease activity | biological process | GO:0032074 | 3 | 2 | 16441 | 1675 |
TMBIM6,NEIL1 |
| 2.901e-02 | -3.54 | negative regulation of blood vessel remodeling | biological process | GO:0060313 | 3 | 2 | 16441 | 1675 |
CST3,ABR |
| 2.901e-02 | -3.54 | ureter morphogenesis | biological process | GO:0072197 | 3 | 2 | 16441 | 1675 |
SOX8,SOX9 |
| 2.901e-02 | -3.54 | regulation of mitotic centrosome separation | biological process | GO:0046602 | 3 | 2 | 16441 | 1675 |
KIF11,NEK2 |
| 2.901e-02 | -3.54 | positive regulation of CD8-positive, alpha-beta T cell proliferation | biological process | GO:2000566 | 3 | 2 | 16441 | 1675 |
HLA-E,HLA-A |
| 2.901e-02 | -3.54 | nuclear matrix anchoring at nuclear membrane | biological process | GO:0090292 | 3 | 2 | 16441 | 1675 |
SUN1,SUN2 |
| 2.901e-02 | -3.54 | Harderian gland development | biological process | GO:0070384 | 3 | 2 | 16441 | 1675 |
RARG,SOX9 |
| 2.901e-02 | -3.54 | re-entry into mitotic cell cycle | biological process | GO:0000320 | 3 | 2 | 16441 | 1675 |
CCND1,CCNF |
| 2.901e-02 | -3.54 | lymphocyte migration into lymphoid organs | biological process | GO:0097021 | 3 | 2 | 16441 | 1675 |
ARTN,RET |
| 2.901e-02 | -3.54 | adenine transport | biological process | GO:0015853 | 3 | 2 | 16441 | 1675 |
SLC25A4,SLC25A5 |
| 2.901e-02 | -3.54 | embryonic skeletal limb joint morphogenesis | biological process | GO:0036023 | 3 | 2 | 16441 | 1675 |
OSR2,OSR1 |
| 2.901e-02 | -3.54 | negative regulation of isotype switching to IgE isotypes | biological process | GO:0048294 | 3 | 2 | 16441 | 1675 |
NDFIP1,BCL6 |
| 2.901e-02 | -3.54 | negative regulation of rubidium ion transport | biological process | GO:2000681 | 3 | 2 | 16441 | 1675 |
CAB39,STK39 |
| 2.901e-02 | -3.54 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter | biological process | GO:0072361 | 3 | 2 | 16441 | 1675 |
PPARA,TP53 |
| 2.901e-02 | -3.54 | limb joint morphogenesis | biological process | GO:0036022 | 3 | 2 | 16441 | 1675 |
OSR2,OSR1 |
| 2.901e-02 | -3.54 | regulation of potassium ion import | biological process | GO:1903286 | 3 | 2 | 16441 | 1675 |
ATP1B1,ATP1B3 |
| 2.901e-02 | -3.54 | renal vesicle induction | biological process | GO:0072034 | 3 | 2 | 16441 | 1675 |
SOX8,SOX9 |
| 2.901e-02 | -3.54 | regulation of oxidative phosphorylation uncoupler activity | biological process | GO:2000275 | 3 | 2 | 16441 | 1675 |
PPIF,TWIST1 |
| 2.901e-02 | -3.54 | negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway | biological process | GO:1903298 | 3 | 2 | 16441 | 1675 |
TMBIM6,PINK1 |
| 2.901e-02 | -3.54 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:0035793 | 3 | 2 | 16441 | 1675 |
PDGFA,PDGFB |
| 2.901e-02 | -3.54 | regulation of type III interferon production | biological process | GO:0034344 | 3 | 2 | 16441 | 1675 |
DDX58,IFIH1 |
| 2.901e-02 | -3.54 | kidney mesenchyme morphogenesis | biological process | GO:0072131 | 3 | 2 | 16441 | 1675 |
OSR1,BMP7 |
| 2.901e-02 | -3.54 | response to interleukin-18 | biological process | GO:0070673 | 3 | 2 | 16441 | 1675 |
RIPK2,IL18R1 |
| 2.901e-02 | -3.54 | pons maturation | biological process | GO:0021586 | 3 | 2 | 16441 | 1675 |
CDK5R1,GRIN1 |
| 2.901e-02 | -3.54 | substrate-dependent cell migration, cell attachment to substrate | biological process | GO:0006931 | 3 | 2 | 16441 | 1675 |
EPB41L5,TNFRSF12A |
| 2.901e-02 | -3.54 | regulation of chorionic trophoblast cell proliferation | biological process | GO:1901382 | 3 | 2 | 16441 | 1675 |
FZD5,ACVR1C |
| 2.901e-02 | -3.54 | protein K33-linked deubiquitination | biological process | GO:1990168 | 3 | 2 | 16441 | 1675 |
YOD1,ZRANB1 |
| 2.901e-02 | -3.54 | positive regulation of metanephric mesenchymal cell migration | biological process | GO:2000591 | 3 | 2 | 16441 | 1675 |
PDGFA,PDGFB |
| 2.901e-02 | -3.54 | negative regulation of p38MAPK cascade | biological process | GO:1903753 | 3 | 2 | 16441 | 1675 |
EZR,DLG1 |
| 2.901e-02 | -3.54 | regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:1900238 | 3 | 2 | 16441 | 1675 |
PDGFA,PDGFB |
| 2.901e-02 | -3.54 | regulation of neurotrophin production | biological process | GO:0032899 | 3 | 2 | 16441 | 1675 |
ADORA1,FURIN |
| 2.901e-02 | -3.54 | ectoderm formation | biological process | GO:0001705 | 3 | 2 | 16441 | 1675 |
ETS2,ELF5 |
| 2.901e-02 | -3.54 | chondrocyte hypertrophy | biological process | GO:0003415 | 3 | 2 | 16441 | 1675 |
RARG,SOX9 |
| 2.901e-02 | -3.54 | negative regulation of peroxisome proliferator activated receptor signaling pathway | biological process | GO:0035359 | 3 | 2 | 16441 | 1675 |
TWIST1,PLIN5 |
| 2.901e-02 | -3.54 | regulation of Rap protein signal transduction | biological process | GO:0032487 | 3 | 2 | 16441 | 1675 |
TIMP2,KIF14 |
| 2.901e-02 | -3.54 | establishment of centrosome localization | biological process | GO:0051660 | 3 | 2 | 16441 | 1675 |
EZR,DLG1 |
| 2.901e-02 | -3.54 | negative regulation of fermentation | biological process | GO:1901003 | 3 | 2 | 16441 | 1675 |
PRKCDBP,TP53 |
| 2.901e-02 | -3.54 | protein K29-linked deubiquitination | biological process | GO:0035523 | 3 | 2 | 16441 | 1675 |
YOD1,ZRANB1 |
| 2.901e-02 | -3.54 | metanephric mesenchyme morphogenesis | biological process | GO:0072133 | 3 | 2 | 16441 | 1675 |
OSR1,BMP7 |
| 2.901e-02 | -3.54 | ureter urothelium development | biological process | GO:0072190 | 3 | 2 | 16441 | 1675 |
OSR1,SOX9 |
| 2.901e-02 | -3.54 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway | biological process | GO:1903297 | 3 | 2 | 16441 | 1675 |
TMBIM6,PINK1 |
| 2.901e-02 | -3.54 | membrane depolarization during SA node cell action potential | biological process | GO:0086046 | 3 | 2 | 16441 | 1675 |
SCN5A,CACNA1D |
| 2.901e-02 | -3.54 | negative regulation of rubidium ion transmembrane transporter activity | biological process | GO:2000687 | 3 | 2 | 16441 | 1675 |
CAB39,STK39 |
| 2.901e-02 | -3.54 | peptidyl-cysteine methylation | biological process | GO:0018125 | 3 | 2 | 16441 | 1675 |
RAB6A,RAB3B |
| 2.901e-02 | -3.54 | lipid glycosylation | biological process | GO:0030259 | 3 | 2 | 16441 | 1675 |
SLC35C1,B4GALNT1 |
| 2.901e-02 | -3.54 | response to interleukin-15 | biological process | GO:0070672 | 3 | 2 | 16441 | 1675 |
ACSL4,JAK3 |
| 2.901e-02 | -3.54 | positive regulation of potassium ion import | biological process | GO:1903288 | 3 | 2 | 16441 | 1675 |
ATP1B1,ATP1B3 |
| 2.904e-02 | -3.54 | GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | MSigDB lists | GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | 74 | 13 | 17758 | 1761 |
B3GALNT1,TNIP1,FUT2,COG2,DOLPP1,MGAT4A,FUT8,MGAT4B,FUT1,GALNT7,POMGNT1,TSPAN7,GCNT1 |
| 2.904e-02 | -3.54 | CROMER_METASTASIS_UP | MSigDB lists | CROMER_METASTASIS_UP | 74 | 13 | 17758 | 1761 |
GNS,FADS2,PLCG1,MICB,SH3BGRL,TSC22D3,PGRMC1,TFAP2C,AGFG2,RPN2,ARHGDIB,SLC25A36,TMEM63A |
| 2.907e-02 | -3.54 | aminoglycan biosynthetic process | biological process | GO:0006023 | 110 | 18 | 16441 | 1675 |
CHSY3,B3GALT6,SLC35D2,B3GNT7,B3GNT2,HSPG2,XYLT1,SDC4,B4GALT4,DSE,SDC1,CHPF,GLCE,HS6ST1,XYLT2,HS3ST3B1,ST3GAL1,NDST3 |
| 2.907e-02 | -3.54 | PA28_beta | pfam domains | PF02252 | 3 | 2 | 16629 | 1696 |
PSME1,PSME2 |
| 2.907e-02 | -3.54 | RIG-I_C-RD | pfam domains | PF11648 | 3 | 2 | 16629 | 1696 |
DDX58,IFIH1 |
| 2.907e-02 | -3.54 | OxoGdeHyase_C | pfam domains | PF16870 | 3 | 2 | 16629 | 1696 |
DHTKD1,OGDHL |
| 2.907e-02 | -3.54 | SPAR_C | pfam domains | PF11881 | 3 | 2 | 16629 | 1696 |
SIPA1L2,SIPA1L1 |
| 2.907e-02 | -3.54 | AMOP | pfam domains | PF03782 | 3 | 2 | 16629 | 1696 |
SUSD2,ISM1 |
| 2.907e-02 | -3.54 | SRC-1 | pfam domains | PF08832 | 3 | 2 | 16629 | 1696 |
NCOA3,NCOA2 |
| 2.907e-02 | -3.54 | CITED | pfam domains | PF04487 | 3 | 2 | 16629 | 1696 |
CITED2,CITED4 |
| 2.907e-02 | -3.54 | RasGAP_C | pfam domains | PF03836 | 3 | 2 | 16629 | 1696 |
IQGAP3,IQGAP1 |
| 2.907e-02 | -3.54 | Cmyb_C | pfam domains | PF09316 | 3 | 2 | 16629 | 1696 |
MYBL1,MYBL2 |
| 2.907e-02 | -3.54 | COR | pfam domains | PF16095 | 3 | 2 | 16629 | 1696 |
LRRK1,DAPK1 |
| 2.907e-02 | -3.54 | ETS_PEA3_N | pfam domains | PF04621 | 3 | 2 | 16629 | 1696 |
ETV4,ETV5 |
| 2.907e-02 | -3.54 | PI3K_p85B | pfam domains | PF02192 | 3 | 2 | 16629 | 1696 |
PIK3CD,PIK3CA |
| 2.907e-02 | -3.54 | UDPGP | pfam domains | PF01704 | 3 | 2 | 16629 | 1696 |
UAP1,UGP2 |
| 2.907e-02 | -3.54 | Runt | pfam domains | PF00853 | 3 | 2 | 16629 | 1696 |
RUNX3,RUNX2 |
| 2.907e-02 | -3.54 | FAM117 | pfam domains | PF15388 | 3 | 2 | 16629 | 1696 |
FAM117A,GLCCI1 |
| 2.907e-02 | -3.54 | RGM_C | pfam domains | PF06534 | 3 | 2 | 16629 | 1696 |
RGMB,RGMA |
| 2.907e-02 | -3.54 | CARD_2 | pfam domains | PF16739 | 3 | 2 | 16629 | 1696 |
DDX58,IFIH1 |
| 2.907e-02 | -3.54 | Nuc_rec_co-act | pfam domains | PF08815 | 3 | 2 | 16629 | 1696 |
NCOA3,NCOA2 |
| 2.907e-02 | -3.54 | Pellino | pfam domains | PF04710 | 3 | 2 | 16629 | 1696 |
PELI3,PELI2 |
| 2.907e-02 | -3.54 | Sox_N | pfam domains | PF12444 | 3 | 2 | 16629 | 1696 |
SOX8,SOX9 |
| 2.907e-02 | -3.54 | PA28_alpha | pfam domains | PF02251 | 3 | 2 | 16629 | 1696 |
PSME1,PSME2 |
| 2.907e-02 | -3.54 | CDI | pfam domains | PF02234 | 3 | 2 | 16629 | 1696 |
CDKN1B,CDKN1C |
| 2.907e-02 | -3.54 | ASD1 | pfam domains | PF08688 | 3 | 2 | 16629 | 1696 |
SHROOM3,SHROOM2 |
| 2.907e-02 | -3.54 | PA26 | pfam domains | PF04636 | 3 | 2 | 16629 | 1696 |
SESN3,SESN1 |
| 2.907e-02 | -3.54 | RGM_N | pfam domains | PF06535 | 3 | 2 | 16629 | 1696 |
RGMB,RGMA |
| 2.907e-02 | -3.54 | P4Ha_N | pfam domains | PF08336 | 3 | 2 | 16629 | 1696 |
P4HA2,P4HA3 |
| 2.907e-02 | -3.54 | Popeye | pfam domains | PF04831 | 3 | 2 | 16629 | 1696 |
POPDC3,BVES |
| 2.907e-02 | -3.54 | DUF1518 | pfam domains | PF07469 | 3 | 2 | 16629 | 1696 |
NCOA3,NCOA2 |
| 2.907e-02 | -3.54 | RunxI | pfam domains | PF08504 | 3 | 2 | 16629 | 1696 |
RUNX3,RUNX2 |
| 2.907e-02 | -3.54 | DUF4071 | pfam domains | PF13281 | 3 | 2 | 16629 | 1696 |
MAP3K5,MAP3K6 |
| 2.907e-02 | -3.54 | Anillin | pfam domains | PF08174 | 3 | 2 | 16629 | 1696 |
RTKN2,ANLN |
| 2.907e-02 | -3.54 | Neuregulin | pfam domains | PF02158 | 3 | 2 | 16629 | 1696 |
NRG2,NRG1 |
| 2.913e-02 | -3.54 | CACNA1A (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit) | protein interactions | 773 | 97 | 17 | 16036 | 1726 |
GRN,LTBP1,HSPG2,CALM3,FBLN1,CACNB4,TSPAN7,LTBP3,CALM2,BTG3,MEGF8,CABP1,MATN2,ABCA2,BCL6,CYSRT1,PCSK5 |
| 2.918e-02 | -3.53 | upper_aerodigestive_tract-tonsil-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-tonsil-carcinoma-squamous_cell_carcinoma | 52 | 10 | 17775 | 1757 |
TAPBP,MUC16,AKT1,GUSB,MACC1,PTEN,PIK3CA,TP53,ERBB2,ZFAND5 |
| 2.919e-02 | -3.53 | WWE | prosite domains | PS50918 | 12 | 4 | 11866 | 1235 |
PARP12,TIPARP,RNF146,DTX4 |
| 2.920e-02 | -3.53 | AGCATTA,MIR-155 | MSigDB lists | AGCATTA,MIR-155 | 129 | 20 | 17758 | 1761 |
SYPL1,TRIM2,INPP5D,RAB6A,C3orf18,ETS1,PSIP1,NFIX,CARHSP1,WEE1,RAB11FIP2,SCG2,TIMM8A,KBTBD2,SGK3,CAB39,SLC39A10,NDFIP1,ATP2B1,PKIA |
| 2.923e-02 | -3.53 | CAFFAREL_RESPONSE_TO_THC_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_DN | 31 | 7 | 17758 | 1761 |
CALM2,CALM3,PPIF,ZWINT,SESN1,CDK1,CALM1 |
| 2.923e-02 | -3.53 | GROSS_ELK3_TARGETS_DN | MSigDB lists | GROSS_ELK3_TARGETS_DN | 31 | 7 | 17758 | 1761 |
FTH1,PGM1,ACOX2,OAS3,MAFF,CTH,SOCS3 |
| 2.923e-02 | -3.53 | REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | MSigDB lists | REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | 31 | 7 | 17758 | 1761 |
CALM2,CALM3,GNB5,DLG3,PLCB2,CALM1,DLG1 |
| 2.923e-02 | -3.53 | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 31 | 7 | 17758 | 1761 |
CCND1,CDH3,JAK1,IGF1R,TACC1,CALD1,ITGA6 |
| 2.923e-02 | -3.53 | HALLMARK_NOTCH_SIGNALING | MSigDB lists | HALLMARK_NOTCH_SIGNALING | 31 | 7 | 17758 | 1761 |
CCND1,ARRB1,HES1,NOTCH3,FZD5,FZD7,DTX4 |
| 2.923e-02 | -3.53 | BIOCARTA_MYOSIN_PATHWAY | MSigDB lists | BIOCARTA_MYOSIN_PATHWAY | 31 | 7 | 17758 | 1761 |
ARHGEF19,ARHGEF3,PKN1,ARHGEF11,ARHGEF9,ARHGEF16,ARHGEF4 |
| 2.923e-02 | -3.53 | PID_AR_NONGENOMIC_PATHWAY | MSigDB lists | PID_AR_NONGENOMIC_PATHWAY | 31 | 7 | 17758 | 1761 |
PLCG1,AKT1,FOS,PLCB2,PLCG2,PIK3R1,PIK3CA |
| 2.923e-02 | -3.53 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP | 31 | 7 | 17758 | 1761 |
UNKL,GCLM,GCLC,PHLPP2,C3orf58,OSGIN1,C5orf30 |
| 2.923e-02 | -3.53 | MODULE_229 | MSigDB lists | MODULE_229 | 31 | 7 | 17758 | 1761 |
DHX8,TFAP4,CITED2,FOS,SOX9,KLF7,GTF2F2 |
| 2.923e-02 | -3.53 | RIZ_ERYTHROID_DIFFERENTIATION_HEMGN | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_HEMGN | 31 | 7 | 17758 | 1761 |
PITX2,PBX3,NFE2L3,KLF5,NR4A2,E2F8,FOSB |
| 2.923e-02 | -3.53 | VALK_AML_CLUSTER_3 | MSigDB lists | VALK_AML_CLUSTER_3 | 31 | 7 | 17758 | 1761 |
ENPP4,COL4A5,BLVRA,SEPP1,IL6ST,AIM1,WBP5 |
| 2.923e-02 | -3.53 | ZWANG_EGF_PERSISTENTLY_UP | MSigDB lists | ZWANG_EGF_PERSISTENTLY_UP | 31 | 7 | 17758 | 1761 |
RHOBTB2,TMTC1,IFIT3,FAM169A,CCDC149,POR,CXorf57 |
| 2.924e-02 | -3.53 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | 195 | 28 | 17758 | 1761 |
SEC23A,KIF20A,LGALS3,GCLC,PBK,LITAF,PRSS22,ISYNA1,NPC2,MCFD2,SLC20A1,PHLDA1,TXNDC11,CDK1,ELF3,SOCS3,EPCAM,UAP1,RANBP1,BUB1,SPCS3,MANF,CCNB2,S100A6,CKAP4,ACOT7,WBP5,CKS2 |
| 2.924e-02 | -3.53 | GSE17721_0.5H_VS_12H_LPS_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDM_DN | 195 | 28 | 17758 | 1761 |
CPD,SEC23A,PMPCB,BCAM,UGP2,IL15RA,CRYM,RASA2,PDIA5,NDRG2,DNER,SPTLC2,KREMEN1,ABR,NCOA3,RPS6KA2,ADRBK1,PVRL2,GDE1,TMEM30A,AMMECR1,MDFIC,CTTN,PIKFYVE,CITED2,NR2C1,RARG,STARD3NL |
| 2.924e-02 | -3.53 | GSE17721_POLYIC_VS_CPG_16H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_16H_BMDM_UP | 195 | 28 | 17758 | 1761 |
CASP3,MTM1,PARP12,SLC37A1,GNPDA1,PSME2,MPP1,ATP8A1,INPP5D,LRP4,GALNT7,GPSM2,BCL2L1,PPP1R14C,ASB13,COL12A1,NRP2,APOBEC3B,PGF,DOPEY2,ADD3,HSF2,FRYL,N4BP3,SLC44A1,FXYD5,IRF2,RAB27B |
| 2.929e-02 | -3.53 | skin-ear-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-ear-carcinoma-squamous_cell_carcinoma | 521 | 65 | 17775 | 1757 |
CASP3,GAA,EPAS1,SSH1,GNPDA1,RET,TP53,ERBB2,SYTL4,PLXNA1,FANCI,SLC9A7,APOBEC3B,RPS6KA2,PIK3CA,TIPARP,CPD,ORAI2,SGCE,UTRN,ROR1,RBL1,CYP2U1,E2F8,LIFR,HOXC13,NUDT6,NKX3-1,ARHGEF11,CDCA8,CNTNAP2,DSE,B4GALT4,FRY,PTEN,PIK3AP1,ATP5H,TOX2,PRKG1,CD9,ADAM15,IQGAP3,ETV7,RBMS2,MDFI,KCNJ12,NR3C1,MRS2,PPARA,LITAF,C1GALT1C1,PTPRF,FAT4,SERPINA1,FGFR2,CGREF1,NETO2,CSTF2,NR4A2,CABIN1,PLD1,MAP3K5,AFAP1,RUSC1,ARHGEF4 |
| 2.930e-02 | -3.53 | AAAGGAT,MIR-501 | MSigDB lists | AAAGGAT,MIR-501 | 121 | 19 | 17758 | 1761 |
CELSR2,LPGAT1,RET,KIF1C,LRRC1,NFIX,PITX2,RCN1,CACHD1,ACADSB,PIK3AP1,SYT7,AMMECR1,SRR,BCL6,NR4A3,PCDH19,SCN3A,SEPHS1 |
| 2.930e-02 | -3.53 | CRX_NRL_DN.V1_DN | MSigDB lists | CRX_NRL_DN.V1_DN | 121 | 19 | 17758 | 1761 |
SGCE,ERMAP,FMN1,NR4A1,FRMD6,HEBP1,RASA2,SLC25A13,SDC4,PDIA3,NIN,PTER,BAX,NTN4,RTKN2,TNFRSF12A,ECE1,FZD5,RAB27B |
| 2.930e-02 | -3.53 | CTIP_DN.V1_DN | MSigDB lists | CTIP_DN.V1_DN | 121 | 19 | 17758 | 1761 |
RASGRF1,BCAM,KLK5,FAM169A,CDKN1C,CDH22,RUNX3,FAM46C,TSPAN7,ANO1,CARD10,CYP4F3,CTNNBIP1,ADAM15,CCDC82,CLMN,MAPK11,MYH14,CYBRD1 |
| 2.935e-02 | -3.53 | REGULATION_OF_BIOLOGICAL_QUALITY | MSigDB lists | REGULATION_OF_BIOLOGICAL_QUALITY | 412 | 53 | 17758 | 1761 |
GCLM,SLC2A4,ARAP3,PEX6,MTL5,TP53,FTH1,SLC1A3,BCL2L1,ISOC2,ETS1,BARD1,SLC9A7,CDKN2C,PTEN,CD9,BAX,ABCA2,BCL6,CDKN1B,LMAN1,F2R,CDKN2D,OSGIN1,ERAP2,CLCN3,MBP,CD55,AKT1,GCLC,GYLTL1B,CDA,SERTAD3,NPC2,F12,NPHP3,BCAR1,RASA1,EDNRA,ATP1A1,KCNMB4,ACVRL1,ATP7B,FGD6,AURKA,ARF6,AIFM3,F2RL1,IFI6,ABCA1,FGD1,ABCG1,EGLN1 |
| 2.935e-02 | -3.53 | nucleotide kinase activity | molecular function | GO:0019201 | 24 | 6 | 16491 | 1673 |
AK4,CMPK2,DLG3,AK7,MPP1,DLG1 |
| 2.943e-02 | -3.53 | PLASMA_MEMBRANE_PART | MSigDB lists | PLASMA_MEMBRANE_PART | 1128 | 131 | 17758 | 1761 |
LAMP1,BCAM,SLC25A13,EPHA4,SYTL4,SDC1,CACNB4,SLC20A1,GRM5,HTR1D,STIM1,IL6ST,DLG1,FUT1,CLDN4,TRPC1,TACSTD2,SGCE,CD55,ACVR1C,SNTB2,ROR1,SLC25A5,EDNRA,HS6ST1,KCNMB4,SLC25A4,KCNK1,ATP7B,F2RL1,CD99,FXYD3,MERTK,TSPAN7,ITGA3,LYPD3,SLC16A6,KCNN4,OPN3,SORL1,CD70,CACNA1D,PIKFYVE,SLC12A2,ABCC1,FADS2,PODXL2,PCDH1,MFI2,MMD,RGMB,EPHA1,STEAP1,STX3,PTPRF,MMP15,GNAS,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,ATP1B3,SHROOM2,SORBS1,SLC2A4,ST14,IL15,CD82,IL27RA,IL13RA1,SLC7A2,DDR1,APC2,BCAP31,SYTL2,CDH1,NOTCH3,EPHB4,F2R,PTPRU,SLC11A2,ATP1B1,ERBB2IP,CD40,DAG1,PTPRJ,ATP1A1,SHROOM3,AXL,MMP17,PTK7,EFNA5,HS3ST3B1,ABCA1,LIFR,CD63,TSPAN15,SELL,GABRG2,TGFBR1,CYB561,EFNB1,FZD6,M6PR,NEO1,IL17RB,ADORA1,ITGB8,ATP8B1,TMBIM6,TSPAN13,ERBB3,SGCB,SLC16A5,SYK,ATP2B1,SYPL1,MPP1,GRIN1,SNTB1,AIF1L,BCAR1,CD83,CNTNAP1,ACVRL1,PGRMC1,RYK,ARRB1,FZD5,CD33 |
| 2.944e-02 | -3.53 | RALB (v-ral simian leukemia viral oncogene homolog B) | protein interactions | 5899 | 17 | 5 | 16036 | 1726 |
REPS2,RALBP1,REPS1,CALM1,EXOC8 |
| 2.944e-02 | -3.53 | SALL2 (spalt-like transcription factor 2) | protein interactions | 6297 | 17 | 5 | 16036 | 1726 |
CCNJL,CARD8,ADAMTSL4,LHX6,CUL4B |
| 2.944e-02 | -3.53 | PPFIA3 (protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3) | protein interactions | 8541 | 17 | 5 | 16036 | 1726 |
PTPRF,PTPRU,CAST,RAB3IL1,PPFIBP2 |
| 2.944e-02 | -3.53 | CPT2 (carnitine palmitoyltransferase 2) | protein interactions | 1376 | 17 | 5 | 16036 | 1726 |
GNAS,ALDH7A1,ATP1B3,ATP1B1,ARHGEF26 |
| 2.944e-02 | -3.53 | LOXL2 (lysyl oxidase-like 2) | protein interactions | 4017 | 17 | 5 | 16036 | 1726 |
PDIA3,HDAC1,TINAGL1,KLK5,PLAUR |
| 2.944e-02 | -3.53 | EIF2AK3 (eukaryotic translation initiation factor 2-alpha kinase 3) | protein interactions | 9451 | 17 | 5 | 16036 | 1726 |
HLA-C,GLT8D2,HLA-E,DNAJC3,BCL6 |
| 2.944e-02 | -3.53 | RAB25 (RAB25, member RAS oncogene family) | protein interactions | 57111 | 17 | 5 | 16036 | 1726 |
MYO5B,TGFBR1,RAB11FIP2,OPTN,RAB11FIP1 |
| 2.944e-02 | -3.53 | ESPL1 (extra spindle pole bodies like 1, separase) | protein interactions | 9700 | 17 | 5 | 16036 | 1726 |
PPP2R5A,CCNB1,CDK1,PTTG1,CKS2 |
| 2.944e-02 | -3.53 | TRPV4 (transient receptor potential cation channel, subfamily V, member 4) | protein interactions | 59341 | 17 | 5 | 16036 | 1726 |
YES1,PACSIN2,PACSIN1,ITCH,CALM1 |
| 2.953e-02 | -3.52 | XU_GH1_AUTOCRINE_TARGETS_UP | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_UP | 229 | 32 | 17758 | 1761 |
UGT8,PPM1J,BLVRB,HERC5,PBX3,AES,FAM198B,OAT,SEPP1,MERTK,SH3KBP1,NRP2,RNF220,BMP7,ECI2,RIMS2,SMAGP,SGCE,SPEF2,GGH,CDCA2,ROR1,ALCAM,SFXN5,STEAP1,MYL12A,STK17A,CNTNAP1,SLC25A4,AXL,NR3C2,CYBRD1 |
| 2.954e-02 | -3.52 | LIN7A (lin-7 homolog A (C. elegans)) | protein interactions | 8825 | 35 | 8 | 16036 | 1726 |
KCNJ12,SNTB2,DLG1,MPP5,DLG3,SLC20A1,PXDC1,ABCA1 |
| 2.954e-02 | -3.52 | UGDH (UDP-glucose 6-dehydrogenase) | protein interactions | 7358 | 35 | 8 | 16036 | 1726 |
SIRT1,TGOLN2,GGH,CTTN,HSPB1,PRKACA,PDIA6,FAS |
| 2.954e-02 | -3.52 | ADD1 (adducin 1 (alpha)) | protein interactions | 118 | 35 | 8 | 16036 | 1726 |
CASP3,SMARCA2,ATP1A1,CALM1,HDAC1,PRKACA,SPTB,ANKRD29 |
| 2.954e-02 | -3.52 | TEC (tec protein tyrosine kinase) | protein interactions | 7006 | 35 | 8 | 16036 | 1726 |
PLCG1,JAK1,PLCG2,PIK3R1,TP53,PLK4,ERBB2,TEC |
| 2.954e-02 | -3.52 | PLD1 (phospholipase D1, phosphatidylcholine-specific) | protein interactions | 5337 | 35 | 8 | 16036 | 1726 |
BIN1,RHOA,PLCG2,PLD1,ARF6,PKN1,RHEB,EGLN1 |
| 2.958e-02 | -3.52 | cytokine production | biological process | GO:0001816 | 118 | 19 | 16441 | 1675 |
CD55,ADGRG1,RGCC,BTN3A1,BTN3A2,IL18,RNF19B,LTBP3,OPTN,DLG1,NOD2,IRF7,PIK3CD,F2RL1,ABCA1,S100A13,TMEM173,RASGRP1,PCSK5 |
| 2.967e-02 | -3.52 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon) | protein interactions | 7531 | 364 | 51 | 16036 | 1726 |
LMO7,CASP3,PPP1R2,TBC1D1,DCAF7,TP53,PKP2,KIF23,FTH1,FBXO6,PDIA4,HDAC9,TOP2A,RASSF8,KIF5B,IGF1R,CDK16,RGS3,OSBPL3,FAM13B,REEP1,CFAP43,KLC3,CDKN1B,ALDH7A1,TIAM1,MAP3K3,RASGRF1,ING1,ARHGEF28,AKT1,CALM1,KIF1C,MCFD2,SAV1,BCAR1,IRS2,NGFRAP1,RAB11FIP2,STK26,SH3BP4,RAB11FIP1,ARRB1,CDK18,CENPE,MAP3K5,SHROOM2,TBC1D4,HSPB1,ISOC1,USP43 |
| 2.969e-02 | -3.52 | MAPK signaling pathway | KEGG pathways | ko04010 | 255 | 38 | 6908 | 758 |
PLA2G4A,CASP3,RPS6KA1,RASA2,TP53,CACNA2D2,TGFBR1,MRAS,PRKACA,PDGFB,CACNB4,FGF19,MECOM,PDGFA,RPS6KA2,DUSP10,MAPK11,CACNA1D,RASGRP1,MAP3K3,RASGRF1,AKT1,NR4A1,RAPGEF2,ELK1,DUSP4,FOS,MAP3K6,MAPK8IP1,RASA1,RASGRP2,FAS,MAPKAPK2,FGFR2,ARRB1,MAP3K5,HSPB1,MAPK12 |
| 2.969e-02 | -3.52 | MAPK signaling pathway | KEGG pathways | hsa04010 | 255 | 38 | 6908 | 758 |
PLA2G4A,CASP3,RASA2,RPS6KA1,TP53,CACNA2D2,TGFBR1,MRAS,CACNB4,PDGFB,PRKACA,FGF19,MECOM,PDGFA,RPS6KA2,DUSP10,MAPK11,CACNA1D,RASGRP1,MAP3K3,RASGRF1,AKT1,NR4A1,RAPGEF2,DUSP4,ELK1,FOS,MAP3K6,MAPK8IP1,RASA1,FAS,RASGRP2,MAPKAPK2,FGFR2,ARRB1,MAP3K5,HSPB1,MAPK12 |
| 2.972e-02 | -3.52 | Plasma membrane estrogen receptor signaling | Pathway Interaction DB | er_nongenomic_pathway | 26 | 8 | 2227 | 331 |
RHOA,AKT1,IGF1R,PIK3R1,PIK3CA,MAPK11,PLCB2,BCAR1 |
| 2.972e-02 | -3.52 | G-protein alpha-subunit binding | molecular function | GO:0001965 | 18 | 5 | 16491 | 1673 |
NUCB1,IGF1R,RGS14,F2R,F2RL1 |
| 2.972e-02 | -3.52 | cysteine-type endopeptidase activator activity involved in apoptotic process | molecular function | GO:0008656 | 18 | 5 | 16491 | 1673 |
CDKN1B,CARD8,NKX3-1,CTSC,NGFRAP1 |
| 2.974e-02 | -3.52 | Anchoring fibril formation | REACTOME pathways | R-HSA-2214320 | 7 | 3 | 8202 | 867 |
COL7A1,BMP1,TLL2 |
| 2.974e-02 | -3.52 | NrCAM interactions | REACTOME pathways | R-HSA-447038 | 7 | 3 | 8202 | 867 |
DLG3,NRP2,DLG1 |
| 2.974e-02 | -3.52 | CREB phosphorylation | REACTOME pathways | R-HSA-199920 | 7 | 3 | 8202 | 867 |
MAPKAPK2,RPS6KA2,RPS6KA1 |
| 2.976e-02 | -3.51 | human chr1p31 | chromosome location | human chr1p31 | 17 | 4 | 26250 | 1887 |
DIRAS3,PRKAA2,PGM1,LEPR |
| 2.976e-02 | -3.51 | human chr8q24.22 | chromosome location | human chr8q24.22 | 17 | 4 | 26250 | 1887 |
PHF20L1,LRRC6,ST3GAL1,EFR3A |
| 2.976e-02 | -3.51 | KRIEG_HYPOXIA_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_VIA_KDM3A | 52 | 10 | 17758 | 1761 |
NFKBIE,FAM64A,PLAUR,FABP6,VEZT,GDF15,COL7A1,SYTL3,NRP2,RRAGD |
| 2.976e-02 | -3.51 | PRAMOONJAGO_SOX4_TARGETS_UP | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_UP | 52 | 10 | 17758 | 1761 |
TRIM8,RND3,FGD6,AK4,GDF15,DUSP4,PHLDA1,TIPARP,MAFF,IER3 |
| 2.976e-02 | -3.51 | KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS | MSigDB lists | KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS | 52 | 10 | 17758 | 1761 |
CASP3,CASP9,GRIN1,TP53,BAX,GRIN2D,MAPK11,BCL2L1,MAP3K5,MAPK12 |
| 2.976e-02 | -3.51 | KEGG_MTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_MTOR_SIGNALING_PATHWAY | 52 | 10 | 17758 | 1761 |
PRKAA2,PGF,RPS6KA2,AKT1,RPS6KA1,PIK3R1,PIK3CA,CAB39,PIK3CD,RHEB |
| 2.976e-02 | -3.51 | GRABARCZYK_BCL11B_TARGETS_DN | MSigDB lists | GRABARCZYK_BCL11B_TARGETS_DN | 52 | 10 | 17758 | 1761 |
TIMP2,STAU2,ETV5,OPN3,BCL2L1,CNOT6L,SYK,GM2A,ABCG1,LAMP3 |
| 2.978e-02 | -3.51 | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | 38 | 8 | 17775 | 1757 |
SS18,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 2.978e-02 | -3.51 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | 38 | 8 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,PIK3CA,TP53,IDH1,GNA11 |
| 2.979e-02 | -3.51 | superpathway of L-lysine degradation | BIOCYC pathways | META_PWY-5327 | 6 | 3 | 907 | 115 |
ALDH7A1,CRYM,AASS |
| 2.979e-02 | -3.51 | third_ventricle | COSMIC cancer mutations | third_ventricle | 45 | 9 | 17775 | 1757 |
GNAS,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,IDH1,GNA11 |
| 2.979e-02 | -3.51 | bone-vertebrae-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-vertebrae-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 45 | 9 | 17775 | 1757 |
B3GNT7,IFITM3,CTSC,OSBPL3,PIK3CA,TP53,FAM81A,PLCB2,RUSC1 |
| 2.982e-02 | -3.51 | TP53BP2 (tumor protein p53 binding protein 2) | protein interactions | 7159 | 90 | 16 | 16036 | 1726 |
AMOTL2,PLK1,PPP1R2,FRMD6,ITCH,RASSF7,NDC80,TP53,YES1,BCL2L1,WWP2,RASSF8,CCDC92,LMO4,OTUB2,WWP1 |
| 2.983e-02 | -3.51 | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | MSigDB lists | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | 162 | 24 | 17758 | 1761 |
NCKAP5,MRC2,PINK1,FRMD4A,FLYWCH2,MBNL3,ABCG2,STRADB,RNF182,TNS1,BCL2L1,SLC25A5,FAM46C,SPTB,FECH,MARCH8,SESN3,MATN2,SLC4A3,ZDHHC23,ADIPOR1,ESPN,RAP1GAP,GPR161 |
| 2.983e-02 | -3.51 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | 162 | 24 | 17758 | 1761 |
COL6A2,PRSS23,TESK1,MRS2,C6orf106,ERBB2,ICMT,SBF1,ATP10D,CASP4,RASGRP2,ABCD4,LLGL2,RGS3,PHTF1,ABCB1,TLE1,RGS14,PDIA6,LRIF1,NR3C2,CBX7,NUP85,MED22 |
| 2.983e-02 | -3.51 | GSE22045_TREG_VS_TCONV_UP | MSigDB lists | GSE22045_TREG_VS_TCONV_UP | 162 | 24 | 17758 | 1761 |
PPIF,COL9A3,PBK,SDC4,MTL5,ABCG2,TTC7A,HTATIP2,ATP8B3,VASH1,KIF11,PCTP,IL18R1,CYP26A1,CD83,COL13A1,SIPA1L1,SLC4A3,NEK2,HS3ST3B1,CENPE,F2R,NCAPG2,NAGA |
| 2.983e-02 | -3.51 | SERVITJA_ISLET_HNF1A_TARGETS_UP | MSigDB lists | SERVITJA_ISLET_HNF1A_TARGETS_UP | 162 | 24 | 17758 | 1761 |
PLA2G4A,OPLAH,PCOLCE,TIMP2,SERPINE2,LGALS3,IFITM3,BLVRB,COL18A1,NDRG2,ARHGDIB,RAB38,SDC1,STK17B,CTSC,CSF1,ITGA7,COL6A1,SCARA3,SERPINB1,SYTL3,GAB1,ACOT7,CYP1B1 |
| 2.983e-02 | -3.51 | GCNP_SHH_UP_EARLY.V1_DN | MSigDB lists | GCNP_SHH_UP_EARLY.V1_DN | 162 | 24 | 17758 | 1761 |
MYO5B,AMOTL2,PLA2G4A,HES1,NLRX1,GUSB,NUB1,PPFIBP2,GRIN1,CRABP2,MERTK,ETS1,LTBP3,SIX4,PITX2,GABRD,POPDC3,PLK2,AIM1,NR4A2,PPP2R3C,CITED2,SMYD5,RRAGD |
| 2.986e-02 | -3.51 | Phospholipase C-mediated cascade: FGFR1 | REACTOME pathways | R-HSA-5654219 | 49 | 10 | 8202 | 867 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA |
| 2.990e-02 | -3.51 | regulation of branching involved in ureteric bud morphogenesis | biological process | GO:0090189 | 24 | 6 | 16441 | 1675 |
TACSTD2,SOX8,HOXB7,LGR4,SOX9,SIX4 |
| 2.991e-02 | -3.51 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | 187 | 27 | 17758 | 1761 |
PLK1,MX1,ARAP2,CENPA,MRC2,TXN,SEC61B,S100A11,PSME2,PTGER4,HMGN3,COL7A1,CCNF,IFIT3,NRP2,CD83,PSMD1,TIMP3,CDH1,CTSC,RRBP1,AKR1B1,OSTF1,IFIT1,GLA,TRAF5,SULT2B1 |
| 2.991e-02 | -3.51 | GSE13306_RA_VS_UNTREATED_TCONV_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_UP | 187 | 27 | 17758 | 1761 |
CYP26B1,LAMP1,BMF,NF2,IGFBP6,TBC1D8B,ATP8A1,BCL9,CD82,IL27RA,PRKAR2B,NENF,ADCK5,SAV1,NPHP3,PHLDA1,ARF4,LRRC45,NOV,COL13A1,CSF1,CCDC82,IRF7,TANC2,LTA4H,PRR15,GM2A |
| 2.991e-02 | -3.51 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 187 | 27 | 17758 | 1761 |
PMPCB,LZTFL1,PDGFC,SORT1,MMD,STAU2,OXR1,XYLT1,TMX4,TGOLN2,INTS8,MGST2,REPS1,SAC3D1,PRIM1,ALDH3B1,SIPA1L2,RPS6KA2,PPP2R5A,ZNF823,MEGF8,STK38,PRPS2,PAPSS1,ZDHHC7,PLCB2,SLC27A3 |
| 2.991e-02 | -3.51 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | 187 | 27 | 17758 | 1761 |
CCNI,SORT1,FOXJ2,RASA2,SYNE2,ATP2C2,ARFGEF1,TESK2,NDRG2,SLC35C1,YES1,LDB2,TP53INP2,MESDC2,PLS3,ATP6V0B,WIPI1,KBTBD2,ZDHHC12,FJX1,RRBP1,DLG1,ADAM15,TMBIM6,ESPN,F2R,PARP9 |
| 2.991e-02 | -3.51 | GSE15767_MED_VS_SCS_MAC_LN_DN | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_DN | 187 | 27 | 17758 | 1761 |
SIGIRR,ADAMTS2,FAM92A1,DAP,DNAJB2,CD82,MBNL3,IL27RA,TRIB2,ITPR3,ETS1,IL18R1,PSIP1,SP4,SS18,PLCG1,HLF,SETDB2,SIPA1L1,PLEKHF1,MAPK11,TMEM64,DLG3,NDFIP1,CBX7,RARG,FAH |
| 2.991e-02 | -3.51 | AAANWWTGC_UNKNOWN | MSigDB lists | AAANWWTGC_UNKNOWN | 187 | 27 | 17758 | 1761 |
ZNF462,DPYSL5,TGIF1,SORT1,TBC1D8B,ATP1B1,PCTP,HOXB2,FZD7,SOX13,DTX3L,TFAP4,FOXP2,MAN2A2,KLF12,SHC3,FGFR2,PHTF1,STEAP2,BCL6,EIF4EBP2,EFNA5,PRIMA1,CACNA1D,CITED2,TRAM1,DIS3L |
| 3.005e-02 | -3.51 | regulation of phospholipase activity | biological process | GO:0010517 | 95 | 16 | 16441 | 1675 |
CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,ARF4,EDNRA,CALM2,PLCG1,ADRBK1,FGFR2,CYR61,ITPR1,PLCB2,RASGRP1 |
| 3.005e-02 | -3.51 | icosanoid metabolic process | biological process | GO:0006690 | 95 | 16 | 16441 | 1675 |
PLA2G4A,FAM213B,MGST2,RNPEP,CYP4F3,MAPKAPK2,CYP1A1,FAAH,CYP2S1,CYP2U1,LTA4H,PTGES,SYK,ABCC1,GPX4,CYP1B1 |
| 3.005e-02 | -3.51 | fatty acid derivative metabolic process | biological process | GO:1901568 | 95 | 16 | 16441 | 1675 |
PLA2G4A,FAM213B,MGST2,RNPEP,CYP4F3,MAPKAPK2,CYP1A1,FAAH,CYP2S1,CYP2U1,LTA4H,PTGES,SYK,GPX4,CYP1B1,ABCC1 |
| 3.006e-02 | -3.50 | EPHA2 forward signaling | Pathway Interaction DB | epha2_fwdpathway | 17 | 6 | 2227 | 331 |
RHOA,BCAR1,TIAM1,PIK3R1,ARHGAP35,PIK3CA |
| 3.006e-02 | -3.50 | V$AP1_Q6_01 | MSigDB lists | V$AP1_Q6_01 | 255 | 35 | 17758 | 1761 |
SEMA6B,LRRFIP2,HSPG2,NUAK1,PRSS22,ZNF385B,LMNA,ZFYVE9,FAM46A,ABCA2,SGK1,VAT1,ABCD1,TAGLN2,PIM1,SNX10,TRAK2,MDFI,SMARCA2,ELK3,MCTP1,TRIM8,LONRF3,CAPN6,RGAG1,IGSF8,ZFAND5,GABARAPL1,EPN3,MAP2,S100A5,CAB39,PRKCDBP,TOB1,SNPH |
| 3.007e-02 | -3.50 | RATTENBACHER_BOUND_BY_CELF1 | MSigDB lists | RATTENBACHER_BOUND_BY_CELF1 | 386 | 50 | 17758 | 1761 |
GRN,KLK10,CEP70,SERPINE2,AK7,ESRP1,CUL4B,EPHA4,C6orf106,HERC5,NUP62CL,EPDR1,SLC25A36,AKIRIN1,APLP2,SP100,STIM1,NPNT,RGS3,FRYL,LMO4,COL6A1,CD9,PTPRE,GM2A,FRS3,MBP,ZNF84,SALL4,ANLN,DCP2,SOX13,CNTNAP1,ENPP1,DUOX1,ONECUT1,GPRC5B,ITGA7,LIMK1,TMC5,BMP1,OVOL1,AGFG2,TLE1,GDF11,GLCCI1,SLC25A30,UBE2C,CXorf56,DOCK9 |
| 3.012e-02 | -3.50 | lung epithelium development | biological process | GO:0060428 | 37 | 8 | 16441 | 1675 |
THRB,GRHL2,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB |
| 3.020e-02 | -3.50 | cellular catabolic process | biological process | GO:0044248 | 1338 | 157 | 16441 | 1675 |
CASP3,GAA,AASS,CRYM,CPT2,CNOT8,DNAJC3,CUL4B,HEXB,FBXO2,PSME1,CCNB1,OAT,HDAC6,CALM2,TYMP,CYP1A1,PSMD1,ZFP36,CYP2S1,TINAGL1,ACOX2,APOBEC3G,ERAP2,CYP1B1,PLK1,FBXL16,SPATA18,ITCH,USP18,CDA,AGO4,CCNF,RNF19B,CYP4F3,CDK1,POR,TRIM9,ENPP1,PLCG1,NEIL1,HPSE,GLA,CAPN1,ALDH6A1,DNAJB2,CALM3,GNS,RPL39,BDH1,NEK2,PCYOX1,AHCY,ZRANB1,MYLIP,GAD1,MCCC2,CYP26B1,PRODH,CALM1,PYM1,PDE5A,TP53INP2,PSMA4,AMDHD1,DCP2,NUDT16,H1F0,FAAH,AURKA,YOD1,CTSA,PLD1,RNF146,XDH,USP43,PLA2G4A,UPF3B,PSME2,PTTG1,MVB12B,LPIN3,PRKACA,CYP39A1,CYP26A1,RAD23A,CYP4F11,KIF14,FABP6,PLCG2,DAB2IP,GOT1,ECE1,PDE4D,PHKA2,LGMN,NAGA,GM2A,CTH,SIRT1,ENPP4,SEC61B,ERLEC1,CDC20,DNAJC10,DUOX1,ALDH3B1,IDE,ALDH5A1,ABHD12,WFS1,PEX2,PRIMA1,CYP2U1,LTA4H,PINK1,CIT,HAL,BLVRB,ERI2,PSMD10,APOBEC3H,CTSZ,FBXO6,DNAJB9,SGPL1,WWP2,RNF128,CTSC,GALNS,UBE2J1,ECI2,WWP1,ABCD1,ALDH7A1,CNOT6L,FAH,PGM1,SHMT1,PSMB4,AMFR,NUB1,UBE2A,FBXO9,BLVRA,RNPEP,CTSL,RPL12,ACADSB,CTSV,ERAP1,ARRB1,ARSB,NDFIP1,UBE2C,ACOT7,DIS3L |
| 3.021e-02 | -3.50 | Golgi to endosome transport | biological process | GO:0006895 | 18 | 5 | 16441 | 1675 |
TGOLN2,AP1AR,DOPEY2,SORT1,WIPI1 |
| 3.021e-02 | -3.50 | regulation of receptor recycling | biological process | GO:0001919 | 18 | 5 | 16441 | 1675 |
SCRIB,AP1AR,ECE1,BVES,OPTN |
| 3.021e-02 | -3.50 | mast cell mediated immunity | biological process | GO:0002448 | 18 | 5 | 16441 | 1675 |
PIK3CD,GATA2,S100A13,RASGRP1,NR4A3 |
| 3.021e-02 | -3.50 | regulation of interferon-alpha production | biological process | GO:0032647 | 18 | 5 | 16441 | 1675 |
DDX58,IRF7,RIPK2,IFIH1,NMI |
| 3.021e-02 | -3.50 | pharyngeal system development | biological process | GO:0060037 | 18 | 5 | 16441 | 1675 |
HES1,TGFBR1,ECE1,NKX3-1,SIX4 |
| 3.021e-02 | -3.50 | negative regulation of stem cell proliferation | biological process | GO:2000647 | 18 | 5 | 16441 | 1675 |
CTNNBIP1,OVOL1,FBLN1,NFIB,TP53 |
| 3.021e-02 | -3.50 | regulation of microtubule-based movement | biological process | GO:0060632 | 18 | 5 | 16441 | 1675 |
LAMP1,CFAP20,HDAC6,BBS2,CCSAP |
| 3.021e-02 | -3.50 | organ maturation | biological process | GO:0048799 | 18 | 5 | 16441 | 1675 |
RHOA,FAT4,SEMA4D,ANO6,RET |
| 3.021e-02 | -3.50 | lymphocyte apoptotic process | biological process | GO:0070227 | 18 | 5 | 16441 | 1675 |
PKN1,AKT1,SIVA1,FAS,BAX |
| 3.021e-02 | -3.50 | positive regulation of chondrocyte differentiation | biological process | GO:0032332 | 18 | 5 | 16441 | 1675 |
LOXL2,RUNX2,ACVRL1,POR,SOX9 |
| 3.021e-02 | -3.50 | regulation of B cell apoptotic process | biological process | GO:0002902 | 18 | 5 | 16441 | 1675 |
IRS2,SLC39A10,PTEN,BCL6,BAX |
| 3.022e-02 | -3.50 | negative regulation of mitotic cell cycle phase transition | biological process | GO:1901991 | 158 | 24 | 16441 | 1675 |
PLK1,PSMB4,PSME2,CTDSPL,CDC20,TP53,RGCC,PSMD10,PSME1,PSMA4,CDK1,FANCI,IER3,JADE1,CCND1,E2F7,PSMD1,PTEN,DACT1,CDKN1B,BUB1,FHL1,UBE2C,CTDSP2 |
| 3.022e-02 | -3.50 | ASD1 | prosite domains | PS51306 | 3 | 2 | 11866 | 1235 |
SHROOM3,SHROOM2 |
| 3.022e-02 | -3.50 | LAMP_2 | prosite domains | PS00311 | 3 | 2 | 11866 | 1235 |
LAMP2,LAMP1 |
| 3.022e-02 | -3.50 | 2FE2S_FER_1 | prosite domains | PS00197 | 3 | 2 | 11866 | 1235 |
XDH,AOX1 |
| 3.022e-02 | -3.50 | LAMP_1 | prosite domains | PS00310 | 3 | 2 | 11866 | 1235 |
LAMP2,LAMP1 |
| 3.022e-02 | -3.50 | MOLYBDOPTERIN_EUK | prosite domains | PS00559 | 3 | 2 | 11866 | 1235 |
XDH,AOX1 |
| 3.022e-02 | -3.50 | LYS_HYDROXYLASE | prosite domains | PS01325 | 3 | 2 | 11866 | 1235 |
PLOD3,PLOD2 |
| 3.022e-02 | -3.50 | RUNT | prosite domains | PS51062 | 3 | 2 | 11866 | 1235 |
RUNX3,RUNX2 |
| 3.026e-02 | -3.50 | actin cytoskeleton | cellular component | GO:0015629 | 445 | 57 | 17570 | 1756 |
DDX58,MYL9,BIN1,GAS2L1,LASP1,FBLIM1,SORBS1,BMF,NF2,ADD1,CIT,IQGAP1,FAM101B,APC2,SPTB,SCNN1A,CDH1,RINL,LLGL2,CALD1,DAPK1,ESPN,MYH14,NOTCH3,CTTN,TLN2,MYRIP,NEB,C9orf72,MYO5A,MYO5B,PGM1,FMN1,CORO2A,EZR,YES1,AIF1L,ANLN,BCAR1,MYL12A,STK17B,ARHGAP35,DPYSL3,KLHL2,DCTN6,PLEKHH2,BFSP1,PDLIM3,H1F0,CORO1C,TRIOBP,TMOD2,SPTBN5,ARPC2,SHROOM2,MYL12B,COBL |
| 3.027e-02 | -3.50 | cortical actin cytoskeleton | cellular component | GO:0030864 | 59 | 11 | 17570 | 1756 |
LASP1,SCNN1A,PLEKHH2,CDH1,NF2,LLGL2,CALD1,SPTBN5,ANLN,SHROOM2,SPTB |
| 3.027e-02 | -3.50 | sensory perception of sound | biological process | GO:0007605 | 142 | 22 | 16441 | 1675 |
THRB,TPRN,CASP3,FZD4,CRYM,HEXB,SLC1A3,TMC1,WFS1,LRIG1,TBX18,TFAP2A,CDKN1B,ATP8B1,SERPINB6,ESPN,ALDH7A1,MYH14,CACNA1D,SLC12A2,CDKN2D,SPRY2 |
| 3.027e-02 | -3.50 | male sex differentiation | biological process | GO:0046661 | 142 | 22 | 16441 | 1675 |
REC8,COL9A3,NKX3-1,LGR4,ASPM,SOX9,TFAP2C,TGFBR1,BCL2L1,FNDC3A,SDC1,SIX4,PRDX4,SGPL1,CCND1,PITX2,LRRC6,HOXA9,CTSV,CST3,BAX,SOX8 |
| 3.027e-02 | -3.50 | V$NFAT_Q6 | MSigDB lists | V$NFAT_Q6 | 238 | 33 | 17758 | 1761 |
LASP1,CPEB4,HSPG2,ETV5,NDRG2,RNF182,NKRF,NOTUM,CD274,RAB6A,PDGFB,TSEN34,PRRG4,FOXP2,ADRBK1,RNF128,FJX1,MITF,ELF5,PIK3CD,PDE4D,FRS3,RHOA,ELK3,CAPN6,PITX2,TMEM54,PLOD2,NR4A3,ARF6,COL16A1,NR3C2,JARID2 |
| 3.029e-02 | -3.50 | lipid modification | biological process | GO:0030258 | 150 | 23 | 16441 | 1675 |
MTM1,CPT2,INPP5D,TMEM55B,PIK3R1,PIP4K2C,SLC35C1,PLPPR4,POR,B4GALNT1,ACADSB,PTEN,PLPP3,IMPAD1,PEX2,PIK3CA,ECI2,PIK3C2B,ABCD1,ADIPOR1,PIK3CD,ACOX2,PIKFYVE |
| 3.029e-02 | -3.50 | KRASNOSELSKAYA_ILF3_TARGETS_UP | MSigDB lists | KRASNOSELSKAYA_ILF3_TARGETS_UP | 38 | 8 | 17758 | 1761 |
MX1,PLSCR1,HLA-E,IL6ST,TAP1,IFIT1,IFIT3,IFI6 |
| 3.029e-02 | -3.50 | VALK_AML_WITH_FLT3_ITD | MSigDB lists | VALK_AML_WITH_FLT3_ITD | 38 | 8 | 17758 | 1761 |
HOXA9,LYRM1,PBX3,COL4A5,PIM1,SEPP1,HOXB2,LGALS3BP |
| 3.029e-02 | -3.50 | CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN | MSigDB lists | CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN | 38 | 8 | 17758 | 1761 |
DDB2,KIF14,PLAUR,ARVCF,PIM1,RNPEP,F2R,FAS |
| 3.029e-02 | -3.50 | chrxq21 | MSigDB lists | chrxq21 | 38 | 8 | 17758 | 1761 |
ZMAT1,ARMCX3,PCDH19,POF1B,GLA,SYTL4,ARMCX6,SRPX2 |
| 3.034e-02 | -3.50 | REGULATION_OF_CELL_GROWTH | MSigDB lists | REGULATION_OF_CELL_GROWTH | 45 | 9 | 17758 | 1761 |
CDKN2C,SERTAD3,BCL6,TP53,CDA,CDKN1B,CDKN2D,BCAR1,OSGIN1 |
| 3.034e-02 | -3.50 | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | MSigDB lists | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | 45 | 9 | 17758 | 1761 |
RCN1,IFITM3,SWI5,SLC44A2,AK4,OSTF1,PDK3,SLC25A5,CDK1 |
| 3.034e-02 | -3.50 | GCM_AQP4 | MSigDB lists | GCM_AQP4 | 45 | 9 | 17758 | 1761 |
GPRC5B,SLC4A4,TACC1,LRP4,LRIG1,NDRG2,TMOD2,BBS2,DNER |
| 3.034e-02 | -3.50 | NAKAJIMA_MAST_CELL | MSigDB lists | NAKAJIMA_MAST_CELL | 45 | 9 | 17758 | 1761 |
ENO2,LGALS3,GATA2,CALB2,VAT1,GDF15,GLA,TRIB2,CYP1B1 |
| 3.034e-02 | -3.50 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | 45 | 9 | 17758 | 1761 |
LMO7,AKIRIN1,GATA2,P4HA2,DNAJC3,SGK1,PDK3,BMP2K,CYP26A1 |
| 3.034e-02 | -3.50 | Plexin-like_fold | interpro domains | IPR016201 | 45 | 9 | 18293 | 1814 |
SEMA6B,ITGB8,SEMA4D,MEGF8,ATRNL1,SEMA3G,PLXNA1,SEMA3A,SEMA3B |
| 3.035e-02 | -3.49 | human chr4q21.21 | chromosome location | human chr4q21.21 | 10 | 3 | 26250 | 1887 |
ANXA3,FRAS1,BMP2K |
| 3.035e-02 | -3.49 | human chr1p35 | chromosome location | human chr1p35 | 10 | 3 | 26250 | 1887 |
TMEM200B,IFI6,ADGRB2 |
| 3.035e-02 | -3.49 | human chr8q13.3 | chromosome location | human chr8q13.3 | 10 | 3 | 26250 | 1887 |
LACTB2,TRAM1,NCOA2 |
| 3.035e-02 | -3.49 | human chr20q13 | chromosome location | human chr20q13 | 10 | 3 | 26250 | 1887 |
AURKA,ELMO2,BMP7 |
| 3.035e-02 | -3.49 | human chr5q23.3 | chromosome location | human chr5q23.3 | 10 | 3 | 26250 | 1887 |
CHSY3,SLC27A6,SLC12A2 |
| 3.036e-02 | -3.49 | Loss of Nlp from mitotic centrosomes | REACTOME pathways | R-HSA-380259 | 63 | 12 | 8202 | 867 |
PLK1,CEP70,CNTRL,CEP78,NEK2,PLK4,TUBG1,PRKAR2B,NDE1,CEP41,PRKACA,CDK1 |
| 3.036e-02 | -3.49 | Loss of proteins required for interphase microtubule organizationfrom the centrosome | REACTOME pathways | R-HSA-380284 | 63 | 12 | 8202 | 867 |
PLK1,CEP70,CNTRL,CEP78,NEK2,PLK4,TUBG1,PRKAR2B,NDE1,CEP41,PRKACA,CDK1 |
| 3.036e-02 | -3.49 | Asymmetric localization of PCP proteins | REACTOME pathways | R-HSA-4608870 | 63 | 12 | 8202 | 867 |
PSMD1,PSMB4,FZD4,PSME2,PSMD10,PRICKLE1,PSME1,SCRIB,FZD5,PSMA4,DVL2,FZD7 |
| 3.044e-02 | -3.49 | INPP5D (inositol polyphosphate-5-phosphatase D) | protein interactions | 3635 | 55 | 11 | 16036 | 1726 |
PLCG1,JAK1,TRIP10,INPP5D,UBASH3B,PIK3R1,LRRK1,JAK3,GAB1,SYK,SH3KBP1 |
| 3.052e-02 | -3.49 | proteoglycan biosynthetic process | biological process | GO:0030166 | 58 | 11 | 16441 | 1675 |
CHSY3,B3GALT6,HS6ST1,XYLT2,XYLT1,HS3ST3B1,DSE,NDST3,FOXL1,GLCE,CHPF |
| 3.057e-02 | -3.49 | ORGANIC_ACID_METABOLIC_PROCESS | MSigDB lists | ORGANIC_ACID_METABOLIC_PROCESS | 179 | 26 | 17758 | 1761 |
FADS2,GCLM,ALDH6A1,GCLC,GNE,PPARA,ACO1,SLC7A2,IDH1,CYP4F3,CYP39A1,SLC6A6,ALDH5A1,AGPAT2,ACADSB,SLC27A6,FAAH,ECI2,GOT1,ADIPOR1,ACOX2,LTA4H,GAD1,PTGES,MCCC2,FAH |
| 3.066e-02 | -3.48 | V$USF_02 | MSigDB lists | V$USF_02 | 264 | 36 | 17758 | 1761 |
GRN,ALDH6A1,CPEB4,HOXB7,TESK2,VASH1,FZD6,PLS3,CDKN2C,TFAP4,MDM1,SESN3,RNF128,CYR61,FAM13B,BAX,ANKRD12,MANF,ARMCX6,DVL2,SIRT1,PHF20L1,PLEKHA6,LONRF3,CAPN6,PIK3R1,OGDHL,TIMM8A,HNRNPH2,KBTBD2,FAM117A,GLA,C1orf43,SEMA3A,CXorf56,RAB3IL1 |
| 3.067e-02 | -3.48 | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | 67 | 12 | 17758 | 1761 |
ENPP4,PIAS3,ANXA3,CASP3,ALDH2,IGF1R,JAK1,MMD,TRIP10,STK39,PRKAR2B,CYB5A |
| 3.067e-02 | -3.48 | GNF2_RAD23A | MSigDB lists | GNF2_RAD23A | 67 | 12 | 17758 | 1761 |
MARCH8,FECH,CA2,ERMAP,H1F0,MPP1,BLVRB,FBXO9,EIF2AK1,SPTB,TRAK2,RAD23A |
| 3.069e-02 | -3.48 | PECAM1 interactions | REACTOME pathways | R-HSA-210990 | 12 | 4 | 8202 | 867 |
PLCG1,YES1,ITGAV,INPP5D |
| 3.069e-02 | -3.48 | Miscellaneous substrates | REACTOME pathways | R-HSA-211958 | 12 | 4 | 8202 | 867 |
CYP2U1,CYP4F11,CYP4F3,CYP2S1 |
| 3.069e-02 | -3.48 | Hyaluronan uptake and degradation | REACTOME pathways | R-HSA-2160916 | 12 | 4 | 8202 | 867 |
HMMR,GUSB,HEXB,CHP1 |
| 3.079e-02 | -3.48 | thyroid-carcinoma-papillary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-papillary_carcinoma | 114 | 18 | 17775 | 1757 |
AKT1,ASPM,SYNE2,RET,PIK3R1,TP53,ERBB2,IDH1,GNA11,GNAS,KIF5B,FAT4,CDH1,PTEN,FGFR2,PIK3CA,SPTBN5,JAK3 |
| 3.079e-02 | -3.48 | papillary_carcinoma | COSMIC cancer mutations | papillary_carcinoma | 114 | 18 | 17775 | 1757 |
AKT1,ASPM,SYNE2,RET,PIK3R1,TP53,ERBB2,IDH1,GNA11,GNAS,KIF5B,FAT4,CDH1,PTEN,FGFR2,PIK3CA,SPTBN5,JAK3 |
| 3.082e-02 | -3.48 | Integration of energy metabolism | REACTOME pathways | R-HSA-163685 | 107 | 18 | 8202 | 867 |
PRKAA2,ACACB,IQGAP1,CACNA2D2,PRKAR2B,ITPR2,ITPR3,SLC25A5,PRKACA,GNA11,GNAS,PRKAG2,SLC25A4,GNB5,ITPR1,KCNS3,CACNA1D,PLCB2 |
| 3.086e-02 | -3.48 | CCDC88A (coiled-coil domain containing 88A) | protein interactions | 55704 | 29 | 7 | 16036 | 1726 |
CTSL,AKT1,PRKACA,JADE2,BARD1,CCDC88A,RASSF7 |
| 3.086e-02 | -3.48 | CCND2 (cyclin D2) | protein interactions | 894 | 29 | 7 | 16036 | 1726 |
CALM2,CDKN1B,PSMD10,CALM3,CDKN1C,CALM1,BCL6 |
| 3.086e-02 | -3.48 | ICK (intestinal cell (MAK-like) kinase) | protein interactions | 22858 | 29 | 7 | 16036 | 1726 |
FAM217B,PSMD1,CDK16,CDK1,A4GALT,BMP7,TP53 |
| 3.086e-02 | -3.48 | PLAU (plasminogen activator, urokinase) | protein interactions | 5328 | 29 | 7 | 16036 | 1726 |
CTSL,SERPINB6,PDGFC,PPP4R4,SERPINE2,ST14,PLAUR |
| 3.086e-02 | -3.48 | L1CAM (L1 cell adhesion molecule) | protein interactions | 3897 | 29 | 7 | 16036 | 1726 |
EZR,ITGAV,FBXO6,RPS6KA2,NCAM1,RPS6KA1,RANBP9 |
| 3.089e-02 | -3.48 | regulation of production of molecular mediator of immune response | biological process | GO:0002700 | 103 | 17 | 16441 | 1675 |
KLK5,HLA-E,IL27RA,PKN1,CD40,HLA-A,GPRC5B,NR4A3,NOD2,BCL6,TMBIM6,KLK7,C10orf54,FZD5,JAK3,F2RL1,NDFIP1 |
| 3.089e-02 | -3.48 | PDIA3 (protein disulfide isomerase family A member 3) | protein interactions | 2923 | 105 | 18 | 16036 | 1726 |
MFI2,ITGA6,ERO1A,TAP1,LOXL2,NANS,PLXNA1,HLA-A,PDIA4,TAPBP,ITGA3,CORO1C,ATP5H,COL6A1,RPN2,TAGLN2,ACOT7,DCBLD1 |
| 3.092e-02 | -3.48 | SNX3 (sorting nexin 3) | protein interactions | 8724 | 62 | 12 | 16036 | 1726 |
SEC23A,DAZAP1,CYP1A1,SCNN1A,ZC3H11A,HEBP1,SETD3,GOT1,TAGLN2,BARD1,SPRY2,PLS3 |
| 3.093e-02 | -3.48 | regulation of chondrocyte differentiation | biological process | GO:0032330 | 44 | 9 | 16441 | 1675 |
RUNX2,CTGF,ACVRL1,SOX9,TGFBR1,LOXL2,FAM101B,RARG,POR |
| 3.093e-02 | -3.48 | glycosyl compound catabolic process | biological process | GO:1901658 | 44 | 9 | 16441 | 1675 |
ENPP4,FUCA1,TYMP,CDA,AHCY,APOBEC3H,GLA,APOBEC3G,NAGA |
| 3.093e-02 | -3.48 | sulfur compound catabolic process | biological process | GO:0044273 | 44 | 9 | 16441 | 1675 |
GNS,HPSE,GALNS,HEXB,PCYOX1,AHCY,ARSB,ACOT7,CTH |
| 3.098e-02 | -3.47 | cellular carbohydrate biosynthetic process | biological process | GO:0034637 | 51 | 10 | 16441 | 1675 |
PGM1,B3GNT2,UGP2,AKT1,IMPAD1,AKR1B1,PGM2L1,GOT1,NANS,ISYNA1 |
| 3.100e-02 | -3.47 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | 196 | 28 | 17758 | 1761 |
DDX58,SERPINE2,TAP1,TEX2,RAB38,F12,PRKRA,FAM81A,ASB13,ANTXR1,RNPEP,RNF19B,NIN,AMZ2,NUCB1,TAPBP,PSMD1,ELMO2,MGAT4A,NLRC5,KCNS3,AURKA,IRF2,BUB1,IRF7,STK39,CMPK2,UBE2C |
| 3.100e-02 | -3.47 | SANSOM_APC_TARGETS | MSigDB lists | SANSOM_APC_TARGETS | 196 | 28 | 17758 | 1761 |
WASF3,ILDR1,FLYWCH2,SOX9,NDC80,GGH,DUSP4,TNFRSF19,EMP2,FZD6,MECOM,MMP15,EPN3,ETS2,SIVA1,HOXA9,PASK,FAM20B,TNFRSF12A,PIEZO1,WDR62,SMYD5,TIAM1,ETV4,NEB,SP5,CYBRD1,DIS3L |
| 3.100e-02 | -3.47 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 196 | 28 | 17758 | 1761 |
MX1,COL6A2,TIMP2,NQO1,ATP9A,FAM134A,BSDC1,RASGRP2,SOX13,AKIRIN1,NCOA3,ST5,RPL12,CA2,COQ10A,RALGPS2,CNTRL,SH3BP1,BCL6,NR4A3,TRIM21,ABCD1,USF2,ST3GAL1,F2RL1,NAGA,JARID2,ABCG1 |
| 3.103e-02 | -3.47 | calcium ion transmembrane transporter activity | molecular function | GO:0015085 | 127 | 20 | 16491 | 1673 |
ORAI2,CCDC109B,ATP2C2,GRIN1,CACNA2D2,SLC11A2,ITPR2,ITPR3,CACNB4,SLC8B1,TMC1,NCS1,ITPR1,TRPC1,ITGAV,CACNA1D,TMEM37,TPCN1,ATP2B1,DENND5B |
| 3.106e-02 | -3.47 | sensory organ morphogenesis | biological process | GO:0090596 | 249 | 35 | 16441 | 1675 |
CTHRC1,SOX9,OSR2,SIX4,PPP2R3A,FZD6,GATA2,BMP7,ALDH1A3,FJX1,BAX,TFAP2A,TWIST1,WNT3A,SPRY2,DVL2,SCRIB,PRKRA,ABR,BCAR3,PITX2,FGFR2,PTK7,TBX18,LRIG1,NKD1,NR4A3,HDAC1,GDF11,SOX8,FZD5,OSR1,SHROOM2,RARG,HOXC13 |
| 3.107e-02 | -3.47 | VEGF signaling pathway | KEGG pathways | ko04370 | 61 | 12 | 6908 | 758 |
MAPKAPK2,PLA2G4A,PLCG1,AKT1,PLCG2,PIK3R1,CASP9,PIK3CA,MAPK11,PIK3CD,HSPB1,MAPK12 |
| 3.107e-02 | -3.47 | VEGF signaling pathway | KEGG pathways | hsa04370 | 61 | 12 | 6908 | 758 |
MAPKAPK2,PLA2G4A,PLCG1,AKT1,PLCG2,PIK3R1,CASP9,PIK3CA,MAPK11,PIK3CD,HSPB1,MAPK12 |
| 3.112e-02 | -3.47 | CCAWYNNGAAR_UNKNOWN | MSigDB lists | CCAWYNNGAAR_UNKNOWN | 138 | 21 | 17758 | 1761 |
SPC25,MACC1,ARL4C,TESK2,RAB6A,CCNB1,LDB2,MECOM,FOXP2,ZNRF2,PRCP,IL6ST,MFSD2A,BCL6,PLK4,AKR1B1,ARVCF,RFX5,MYH14,NR3C2,NXT2 |
| 3.112e-02 | -3.47 | GACAATC,MIR-219 | MSigDB lists | GACAATC,MIR-219 | 138 | 21 | 17758 | 1761 |
THRB,SCN5A,FZD4,PTPRU,TACC1,UBASH3B,ZCCHC24,LPGAT1,EPHA4,ETV5,FURIN,RGAG1,ELK1,SP4,DCP2,DAZAP1,KLF9,PDE4D,SLC39A10,CPEB2,NR2C2 |
| 3.112e-02 | -3.47 | IQ | pfam domains | PF00612 | 44 | 9 | 16629 | 1696 |
MYO5B,ASPM,IQGAP1,IQCE,IQCD,MYH14,IQGAP3,NRGN,MYO5A |
| 3.113e-02 | -3.47 | meninges-meningioma | COSMIC cancer mutations | meninges-meningioma | 335 | 44 | 17775 | 1757 |
NF2,FRMD6,SOX9,RET,TP53,ERBB2,ITPR2,OSR2,AIP,CDKN2C,FOXP2,GNS,DOPEY2,ADD3,RPS6KA2,MLPH,WDR44,PTEN,PCYOX1,PIK3CA,IRF2,DAB2IP,ERBB3,TIAM1,RIMS2,CYP1B1,MYO5B,SYPL1,AKT1,PIK3R1,CR2,COL7A1,IDH1,BBS2,SLC25A5,GNA11,GNAS,PPP2R5A,FGFR2,PTK7,ATP7B,TSPAN18,SIPA1L1,EPB41L4A |
| 3.113e-02 | -3.47 | Autointegration results in viral DNA circles | REACTOME pathways | R-HSA-177539 | 3 | 2 | 8202 | 867 |
HMGA1,PSIP1 |
| 3.113e-02 | -3.47 | Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization | REACTOME pathways | R-HSA-180897 | 3 | 2 | 8202 | 867 |
SLC25A4,SLC25A5 |
| 3.113e-02 | -3.47 | Integration of viral DNA into host genomic DNA | REACTOME pathways | R-HSA-175567 | 3 | 2 | 8202 | 867 |
HMGA1,PSIP1 |
| 3.115e-02 | -3.47 | V$MEIS1_01 | MSigDB lists | V$MEIS1_01 | 230 | 32 | 17758 | 1761 |
SPRED1,CDK17,SORBS1,ARMCX3,THRA,ETS1,TNFRSF19,HOXB2,PSIP1,CDKN2C,CTNNBIP1,FOXP2,SS18,FLRT3,NCAM1,MYT1,TIAM1,CKAP4,SIRT1,TGIF1,ATL1,TNIP1,ITCH,FOS,ACADSB,H1F0,TLE1,NRG1,KLF5,C1orf43,CMTM4,KLF7 |
| 3.115e-02 | -3.47 | V$RSRFC4_01 | MSigDB lists | V$RSRFC4_01 | 230 | 32 | 17758 | 1761 |
CPEB4,NDRG2,PPP2R3A,ZNF385B,HDAC9,SCML1,AKIRIN1,RGS3,SLC44A1,TWIST1,TSPAN13,ARMCX6,CRTAP,TRAK2,CYP26B1,SMARCA2,SSH3,RASGRF1,PLEKHA6,TIMP2,ARAP2,S100A4,NR4A1,PANK1,RGAG1,STRADB,ZFAND5,ITGA7,RAP2C,SIPA1L1,FAM117A,EHD1 |
| 3.116e-02 | -3.47 | PITPNB (phosphatidylinositol transfer protein, beta) | protein interactions | 23760 | 23 | 6 | 16036 | 1726 |
PGM2L1,GOT1,OAT,ALDH6A1,HSPB1,LMO4 |
| 3.116e-02 | -3.47 | CSN2 (casein beta) | protein interactions | 1447 | 23 | 6 | 16036 | 1726 |
PLK1,AURKA,ARRB1,CDK1,CUL4B,NEK2 |
| 3.116e-02 | -3.47 | KLHL2 (kelch-like family member 2) | protein interactions | 11275 | 23 | 6 | 16036 | 1726 |
KLHL2,BCAM,ZNF114,TMA16,UBE2C,ZFP36 |
| 3.116e-02 | -3.47 | MMP14 (matrix metallopeptidase 14 (membrane-inserted)) | protein interactions | 4323 | 23 | 6 | 16036 | 1726 |
TIMP3,ITGAV,TIMP2,F12,SDC1,BCAR1 |
| 3.116e-02 | -3.47 | EFHD2 (EF-hand domain family member D2) | protein interactions | 79180 | 23 | 6 | 16036 | 1726 |
RCN1,FBXO6,ARPC2,ENO2,IDH1,DCK |
| 3.116e-02 | -3.47 | STK39 (serine threonine kinase 39) | protein interactions | 27347 | 23 | 6 | 16036 | 1726 |
STK39,PRKCQ,MBP,SLC12A2,NUBP1,EHD1 |
| 3.116e-02 | -3.47 | PLXNB2 (plexin B2) | protein interactions | 23654 | 23 | 6 | 16036 | 1726 |
PLCG1,FBXO6,ARHGEF11,TACC1,HLA-E,LYPD6 |
| 3.117e-02 | -3.47 | PAS | prosite domains | PS50112 | 30 | 7 | 11866 | 1235 |
AHRR,NCOA3,PER3,EPAS1,AHR,NCOA2,PASK |
| 3.119e-02 | -3.47 | LCK (LCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3932 | 135 | 22 | 16036 | 1726 |
CD55,NR3C1,PIK3R1,EZR,PRKCQ,PRKACA,BCAR1,SH3KBP1,RASA1,SOCS3,FAS,PTPRF,PLCG1,AXL,PLCG2,NFKBIA,DLG1,PIK3CA,ADAM15,JAK3,SYK,DEF6 |
| 3.121e-02 | -3.47 | Separation of Sister Chromatids | REACTOME pathways | R-HSA-2467813 | 161 | 25 | 8202 | 867 |
PLK1,ZWINT,CENPA,PSMB4,SPC25,PSME2,CENPI,PTTG1,CDC20,NDC80,CDCA8,PSMD10,PSME1,NUF2,CENPN,PSMA4,PSMD1,PPP2R5A,CDCA5,BUB1,CENPE,NDE1,UBE2C,ESPL1,NUP85 |
| 3.121e-02 | -3.47 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | 171 | 25 | 17758 | 1761 |
CTHRC1,UGP2,GRHL2,PRSS23,IL15,STAT4,LYRM1,AK4,SLC1A3,MORF4L2,FNDC3A,CD40,MNS1,ARF4,NRP2,PLS3,BTG3,UAP1,RAP2C,RAB11FIP1,SELK,SERPINB1,ESYT2,LAMP3,ABCG1 |
| 3.123e-02 | -3.47 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | GO:0001077 | 225 | 32 | 16491 | 1673 |
RUNX2,EPAS1,SOX9,TP53,SIX4,ELF3,TFAP4,GRHL1,GATA2,MITF,FOSB,TFAP2A,MYBL1,ETV4,ELK3,PLSCR1,NR3C1,NR4A1,FOXJ2,MYBL2,PPARA,TFAP2C,ELK1,FOS,NFIB,PITX2,ONECUT1,NCOA3,NR4A3,NR4A2,KLF5,HOXC13 |
| 3.123e-02 | -3.47 | PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1) | protein interactions | 23398 | 7 | 3 | 16036 | 1726 |
PTPRF,PTBP3,ADRBK1 |
| 3.123e-02 | -3.47 | GFRA1 (GDNF family receptor alpha 1) | protein interactions | 2674 | 7 | 3 | 16036 | 1726 |
NCAM1,RET,SOCS3 |
| 3.123e-02 | -3.47 | OSMR (oncostatin M receptor) | protein interactions | 9180 | 7 | 3 | 16036 | 1726 |
ERBB2,JAK1,IL6ST |
| 3.123e-02 | -3.47 | DGKH (diacylglycerol kinase, eta) | protein interactions | 160851 | 7 | 3 | 16036 | 1726 |
DGKH,ARRB1,TRAF5 |
| 3.123e-02 | -3.47 | TUBA1A (tubulin, alpha 1a) | protein interactions | 404053 | 7 | 3 | 16036 | 1726 |
DPYSL5,DPYSL2,DPYSL3 |
| 3.123e-02 | -3.47 | LPAR2 (lysophosphatidic acid receptor 2) | protein interactions | 9170 | 7 | 3 | 16036 | 1726 |
ARHGEF11,SIVA1,BCL6 |
| 3.123e-02 | -3.47 | AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) | protein interactions | 116986 | 7 | 3 | 16036 | 1726 |
PLCG1,NF2,PIK3R1 |
| 3.123e-02 | -3.47 | INTS4P2 (integrator complex subunit 4 pseudogene 2) | protein interactions | 644619 | 7 | 3 | 16036 | 1726 |
ASPM,CKAP4,MRS2 |
| 3.123e-02 | -3.47 | NXN (nucleoredoxin) | protein interactions | 64359 | 7 | 3 | 16036 | 1726 |
GAS2L1,ARRDC1,C9orf9 |
| 3.123e-02 | -3.47 | MAP7D3 (MAP7 domain containing 3) | protein interactions | 79649 | 7 | 3 | 16036 | 1726 |
SH3KBP1,SPINT2,TRAK2 |
| 3.123e-02 | -3.47 | Traf2 (TNF receptor-associated factor 2) | protein interactions | 22030 | 7 | 3 | 16036 | 1726 |
CD40,TNFRSF19,RHEB |
| 3.123e-02 | -3.47 | CD6 (CD6 molecule) | protein interactions | 923 | 7 | 3 | 16036 | 1726 |
ALCAM,CUL4B,NFE2L1 |
| 3.123e-02 | -3.47 | AKIP1 (A kinase (PRKA) interacting protein 1) | protein interactions | 56672 | 7 | 3 | 16036 | 1726 |
SIRT1,PRKACA,BARD1 |
| 3.123e-02 | -3.47 | ZNF503 (zinc finger protein 503) | protein interactions | 84858 | 7 | 3 | 16036 | 1726 |
CCNJL,CYP1A1,PYM1 |
| 3.123e-02 | -3.47 | UNC5B (unc-5 netrin receptor B) | protein interactions | 219699 | 7 | 3 | 16036 | 1726 |
TUBG1,DAP,DAPK1 |
| 3.123e-02 | -3.47 | IFNA14 (interferon, alpha 14) | protein interactions | 3448 | 7 | 3 | 16036 | 1726 |
IFIT1,IFIT3,STIM1 |
| 3.123e-02 | -3.47 | RCOR2 (REST corepressor 2) | protein interactions | 283248 | 7 | 3 | 16036 | 1726 |
HDAC1,HMG20B,HDAC11 |
| 3.123e-02 | -3.47 | ARRDC4 (arrestin domain containing 4) | protein interactions | 91947 | 7 | 3 | 16036 | 1726 |
ARRB1,ITCH,WWP2 |
| 3.123e-02 | -3.47 | L2HGDH (L-2-hydroxyglutarate dehydrogenase) | protein interactions | 79944 | 7 | 3 | 16036 | 1726 |
KLK10,GM2A,CTSV |
| 3.123e-02 | -3.47 | LAT2 (linker for activation of T-cells family member 2) | protein interactions | 7462 | 7 | 3 | 16036 | 1726 |
PLCG1,GAB1,PLCG2 |
| 3.123e-02 | -3.47 | PCDH20 (protocadherin 20) | protein interactions | 64881 | 7 | 3 | 16036 | 1726 |
B3GNT2,ATP1B3,RYK |
| 3.123e-02 | -3.47 | Tmsb4x (thymosin, beta 4, X chromosome) | protein interactions | 19241 | 7 | 3 | 16036 | 1726 |
TLE1,LRIF1,TP53 |
| 3.133e-02 | -3.46 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | 75 | 13 | 17775 | 1757 |
GNAS,CDKN2C,MUC16,AKT1,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,PLXNA1,IDH1,GNA11 |
| 3.133e-02 | -3.46 | Aurora A signaling | Pathway Interaction DB | aurora_a_pathway | 31 | 9 | 2227 | 331 |
CENPA,AKT1,DLGAP5,TACC1,NFKBIA,TP53,AURKA,PRKACA,RASA1 |
| 3.141e-02 | -3.46 | V$XBP1_01 | MSigDB lists | V$XBP1_01 | 130 | 20 | 17758 | 1761 |
ARMCX3,HOXB7,SNTB2,ITCH,MORF4L2,TRIB2,TP53INP2,TSPAN7,PPP2R3A,PRDX4,PDIA4,CCND1,HNRNPH2,NR4A3,PLEKHF1,GLA,PIM1,MANF,KDELR1,SEMA3B |
| 3.141e-02 | -3.46 | V$PR_02 | MSigDB lists | V$PR_02 | 130 | 20 | 17758 | 1761 |
DOCK4,NCKAP5,MBP,ZNF395,CPEB4,ITGA6,FBXO9,PDGFB,SDC1,ETS1,RANBP9,SCNN1A,RGS3,DOLPP1,ELF5,OPN3,BCL6,DUSP10,DLG3,SEMA3A |
| 3.141e-02 | -3.46 | KEGG_TIGHT_JUNCTION | MSigDB lists | KEGG_TIGHT_JUNCTION | 130 | 20 | 17758 | 1761 |
MYL9,RAB3B,RHOA,AKT1,CRB3,PRKCQ,MRAS,F11R,MPP5,YES1,MYL12A,TJP3,LLGL2,PTEN,CLDN4,MYH14,CTTN,PPP2R2D,MYL12B,OCLN |
| 3.144e-02 | -3.46 | Myometrial Relaxation and Contraction Pathways | WikiPathways | WP289 | 155 | 26 | 4455 | 516 |
IGFBP6,CALM1,RGS20,CALM3,PRKCQ,PRKAR2B,GRK6,ITPR2,ITPR3,FOS,PRKACA,CALM2,GNAS,PLCG1,GNB5,ETS2,CALD1,RGS3,ITPR1,PLCG2,ARRB1,IGFBP2,PDE4D,RGS14,MAFF,PKIA |
| 3.151e-02 | -3.46 | nuclear import | biological process | GO:0051170 | 111 | 18 | 16441 | 1675 |
HES1,SEC61B,AKT1,PIK3R1,TP53,PRICKLE1,PDIA3,HTATIP2,DAG1,ZFYVE9,LMNA,NFKBIA,BCL6,JAK3,F2R,SYK,NUP85,TOB1 |
| 3.151e-02 | -3.46 | regulation of cell cycle arrest | biological process | GO:0071156 | 111 | 18 | 16441 | 1675 |
BIN1,PSMB4,FOXM1,CAST,PSME2,TP53,RGCC,PSMD10,PSME1,PRKACA,PSMA4,CDK5R1,TFAP4,CCND1,PSMD1,CDKN1B,DAB2IP,GPER1 |
| 3.154e-02 | -3.46 | papillary | COSMIC cancer mutations | papillary | 60 | 11 | 17775 | 1757 |
ADAMTS2,NF2,AKT1,PTEN,PELI2,DNAJC3,UTRN,PIK3CA,KIF1C,PDK3,ARF6 |
| 3.154e-02 | -3.46 | positive regulation of cell activation | biological process | GO:0050867 | 283 | 39 | 16441 | 1675 |
LAMP1,IL15,INPP5D,RPS6KA1,HLA-E,IL18,CD274,TNFSF9,EFNB1,HLA-A,CTGF,IL6ST,BCL6,PIK3CA,IGFBP2,WNT3A,SLC39A10,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,AKT1,RIPK2,PIK3R1,PRKCQ,YES1,CD40,CD83,IRS2,PVRL2,AXL,NR4A3,NOD2,PPP2R3C,ICOSLG,JAK3,F2RL1 |
| 3.156e-02 | -3.46 | stereocilium | cellular component | GO:0032420 | 38 | 8 | 17570 | 1756 |
DOCK4,TPRN,MPP1,EPS8,ATP8B1,ESPN,TMC1,PLS3 |
| 3.158e-02 | -3.46 | GGTGTGT,MIR-329 | MSigDB lists | GGTGTGT,MIR-329 | 106 | 17 | 17758 | 1761 |
THRB,PCGF5,GGA1,BCL9,PDE5A,DPYSL3,KLHL2,IRF2BPL,KLF12,IL6ST,FOSB,N4BP3,DAPK1,NRG1,PDE4D,SLC39A10,MYT1 |
| 3.159e-02 | -3.45 | negative regulation of cellular biosynthetic process | biological process | GO:0031327 | 1460 | 170 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,ZFP36,SIVA1,MITF,FOSB,PASK,DLG1,IRF2,CRY2,ZBTB18,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,TRIM8,ITCH,CBX6,TFAP2C,EZR,AGO4,LOXL2,PIF1,EDNRA,AHRR,ENPP1,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,GLA,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,MDFIC,RFX5,PIM1,ETV7,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,JAK3,TOB1,RARG,EGLN1,NF2,S100A11,FOXM1,THRA,INPP5D,TP53,OSR2,PDGFA,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,NR2C1,CHP1,SIRT1,DRAP1,ERBB2IP,RAD17,H2AFV,ARHGAP35,NFIX,ATP1A1,RBL1,WFS1,PEX2,OVOL1,TLE1,SLC27A1,NRG1,IRF7,KLF5,CBX7,GLIS3,TNRC6C,NKX3-1,DEPDC1,CPEB4,DAP,PSMD10,NKRF,AES,TRIB2,FGF19,SIX4,FZD6,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,RNF128,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CITED2,CNOT6L,TRIM62,NCOA2,NFE2L3,TGIF1,HES1,IFITM3,RAPGEF2,GCLC,PPARA,PRICKLE1,RUNX3,LEPR,PITX2,BANK1,FGFR2,ACVRL1,NR1D2,TBX18,NMI,NR4A3,ARRB1,HMGA1,OSR1,SOX8,CPEB2,AHR,PKIA,ZBTB33,JARID2 |
| 3.160e-02 | -3.45 | - | gene3d domains | 3.80.20.20 | 7 | 3 | 9988 | 1080 |
ERBB2,ERBB3,IGF1R |
| 3.160e-02 | -3.45 | BROWN_MYELOID_CELL_DEVELOPMENT_DN | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_DN | 122 | 19 | 17758 | 1761 |
BIN1,PAPSS2,IFITM3,PTPN9,PDIA5,ANKRD10,IDE,TIMM8A,GATA2,OSBPL3,FUT8,SPINT2,PGRMC1,AHCY,RAB27B,F2R,NRGN,SYTL3,MGAT5 |
| 3.160e-02 | -3.45 | dermatan sulfate biosynthesis | BIOCYC pathways | META_PWY-6571 | 15 | 5 | 907 | 115 |
CHSY3,DSE,XYLT2,XYLT1,CHPF |
| 3.160e-02 | -3.45 | dermatan sulfate biosynthesis | BIOCYC pathways | HUMAN_PWY-6571 | 15 | 5 | 907 | 115 |
CHSY3,DSE,XYLT2,XYLT1,CHPF |
| 3.163e-02 | -3.45 | regulation of peptide hormone secretion | biological process | GO:0090276 | 216 | 31 | 16441 | 1675 |
ILDR1,ACVR1C,IQGAP1,SYBU,CACNA2D2,HMGN3,PRKAR2B,ITPR2,SYTL4,ITPR3,SLC25A5,PRKACA,SLC8B1,ANO1,GPLD1,GNAS,IRS2,NOV,SLC25A4,SYT7,CDK16,PASK,ITPR1,KCNS3,ARRB1,EFNA5,GPER1,SPCS3,CACNA1D,MYRIP,MYT1 |
| 3.167e-02 | -3.45 | ganglioglioma | COSMIC cancer mutations | ganglioglioma | 25 | 6 | 17775 | 1757 |
AKT1,IDH1,PTEN,GNA11,PIK3CA,TP53 |
| 3.167e-02 | -3.45 | Spitz | COSMIC cancer mutations | Spitz | 25 | 6 | 17775 | 1757 |
KIF5B,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.167e-02 | -3.45 | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | 25 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.167e-02 | -3.45 | Adrenergic signaling in cardiomyocytes | KEGG pathways | hsa04261 | 148 | 24 | 6908 | 758 |
SCN5A,AKT1,CALM1,PIK3R1,CACNA2D2,CALM3,ATP1B1,CACNB4,PRKACA,PPP2R3A,GNAS,CALM2,ATP1A1,PPP2R5A,PIK3CA,PPP2R3C,MAPK11,ATP1B3,CACNA1D,PIK3CD,PLCB2,PPP2R2D,ATP2B1,MAPK12 |
| 3.167e-02 | -3.45 | Adrenergic signaling in cardiomyocytes | KEGG pathways | ko04261 | 148 | 24 | 6908 | 758 |
SCN5A,AKT1,CALM1,PIK3R1,CACNA2D2,CALM3,ATP1B1,CACNB4,PRKACA,PPP2R3A,GNAS,CALM2,ATP1A1,PPP2R5A,PIK3CA,PPP2R3C,MAPK11,ATP1B3,CACNA1D,PIK3CD,PLCB2,PPP2R2D,ATP2B1,MAPK12 |
| 3.171e-02 | -3.45 | cleavage furrow | cellular component | GO:0032154 | 45 | 9 | 17570 | 1756 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,PLK4,PKN1,ARF6,NDE1 |
| 3.171e-02 | -3.45 | cell surface furrow | cellular component | GO:0097610 | 45 | 9 | 17570 | 1756 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,PLK4,PKN1,ARF6,NDE1 |
| 3.175e-02 | -3.45 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | 188 | 27 | 17758 | 1761 |
MX1,PDGFC,TM2D2,SLC37A1,FIGNL1,INPP5D,C5orf30,DHX8,SCRIB,ASB13,SESN1,C3orf58,LGALS3BP,RASA1,HMGXB4,AHRR,NUDT16,MSL1,DOLPP1,WFS1,TMEM51,SLC44A2,FAIM,GLCCI1,MED22,SNX30,NR2C2 |
| 3.175e-02 | -3.45 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_DN | 188 | 27 | 17758 | 1761 |
SORT1,ARHGEF3,CCDC109B,HJURP,LPGAT1,PLAUR,RASA2,PBX3,KCTD12,GTF3A,ITPR2,LACTB2,SDC1,SLC20A1,STK17B,CYB5A,RASSF8,ATP6V0B,FAM63A,BCL6,FGD6,CCDC82,SPCS3,SERPINB1,UBE2C,CKAP4,METAP2 |
| 3.175e-02 | -3.45 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 188 | 27 | 17758 | 1761 |
HMMR,ATL1,SPRED1,CPEB4,GNPDA1,PYROXD2,CUL4B,CDCA8,DHRS3,LMNA,NRP2,FRMD4B,DHX32,SOCS3,PDGFA,NOV,PSMD1,SYT7,VAT1,TNFRSF12A,NFKBIZ,LMAN1,CCNB2,F2RL1,NR3C2,HOXC13,FGD1 |
| 3.175e-02 | -3.45 | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDM_DN | 188 | 27 | 17758 | 1761 |
CCNI,SIGIRR,TRIM2,CCDC109B,NQO1,ESRP1,MRAS,ARHGDIB,RAB38,DNER,SEPP1,C3orf58,ANO1,ATP1A1,ARTN,WIPI1,NR1D2,TIMM8A,AMMECR1,DAPK1,HLA-C,TECR,SCN2A,CITED2,ARF6,RASGRP1,ZBTB33 |
| 3.175e-02 | -3.45 | GSE27786_LIN_NEG_VS_NKTCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_DN | 188 | 27 | 17758 | 1761 |
CDK17,TNIP1,CAST,SAT1,PTTG1,TAP1,KCTD12,IL13RA1,SLC20A1,IRF2BPL,SLC25A4,FAM46A,STK38,MGAT4A,KBTBD2,BDH1,NMI,IRF7,CYP2U1,ITGAV,RGS14,SEMA3A,RARG,RNF146,JARID2,PARP9,ADAMTS16 |
| 3.175e-02 | -3.45 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | 188 | 27 | 17758 | 1761 |
WASF3,HECA,PACSIN2,RHOA,HAL,OSGIN2,TESK2,ATP8B3,DOCK5,ETS1,RNF19B,SYTL2,B4GALNT1,RASGRP2,HLF,FUT2,HPSE,SLC16A6,POF1B,SORL1,PTPRE,CPPED1,CKAP4,GPR161,JARID2,TLL2,EHD1 |
| 3.175e-02 | -3.45 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP | 188 | 27 | 17758 | 1761 |
SEC23A,PMPCB,GAA,PGM1,CENPA,NLRX1,UBE2A,ASAH1,ANLN,WWP2,B4GALNT1,RASGRP2,IER3,ANKRD10,IRS2,SS18,COQ10A,CSTF2,CDKN1B,IRF7,ITGAV,ECE1,TMEM159,MYT1,CDKN2D,MPHOSPH9,NCOA2 |
| 3.175e-02 | -3.45 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDM_DN | 188 | 27 | 17758 | 1761 |
GOLIM4,TXN,DEPDC1,MPP1,DNAJC3,CCDC34,HMG20B,MRAS,NUCB2,NTAN1,BEX2,CD83,MDM1,CTGF,NPNT,DPYSL2,AXL,N4BP3,CLMN,MAPK11,SERPINI1,NFKBIZ,TSPAN13,TMOD2,RP2,TECR,NDFIP1 |
| 3.177e-02 | -3.45 | Regulation of RhoA activity | Pathway Interaction DB | rhoa_reg_pathway | 46 | 12 | 2227 | 331 |
ARHGEF10L,PLEKHG6,RHOA,ARHGEF28,ARHGEF3,ARAP3,ARHGEF11,CDKN1B,ARHGDIB,DEF6,ABR,ARHGAP35 |
| 3.180e-02 | -3.45 | nuclear envelope organization | biological process | GO:0006998 | 73 | 13 | 16441 | 1675 |
PLK1,SUN1,SUN2,SYNE2,SUN3,GPER1,CCNB1,REEP4,CCNB2,NUP85,NUP58,CDK1,LMNA |
| 3.182e-02 | -3.45 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | 163 | 24 | 17758 | 1761 |
CPD,ORAI2,PINK1,REPS2,LPGAT1,GRIN1,IL13RA1,FOXL1,MECOM,CTNNBIP1,AGPAT2,ACVRL1,SERINC2,SORL1,TWIST1,ADIPOR1,NRG1,TACSTD2,FHL1,LTA4H,LZTS1,CRTAP,CYBRD1,RRAGD |
| 3.182e-02 | -3.45 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | 163 | 24 | 17758 | 1761 |
GLIS3,IER5L,NFKBIE,IFITM3,MRPS15,ZC3H11A,DNAJC3,SLC11A2,TCF7,ERBB2IP,FNDC3A,SDC1,TNFRSF19,B4GALNT1,TIMP3,FAT4,KLF12,LRIG1,AIM1,NETO2,PIK3CA,SH3BGRL2,WBSCR27,RAB3IL1 |
| 3.196e-02 | -3.44 | cellular amino acid catabolic process | biological process | GO:0009063 | 119 | 19 | 16441 | 1675 |
PRODH,SHMT1,ALDH6A1,AASS,CRYM,HAL,OAT,AMDHD1,ALDH5A1,ACADSB,ABHD12,PCYOX1,GOT1,AHCY,ALDH7A1,GAD1,MCCC2,CTH,FAH |
| 3.198e-02 | -3.44 | ear | COSMIC cancer mutations | ear | 642 | 78 | 17775 | 1757 |
CASP3,GAA,SSH1,EPAS1,GNPDA1,RET,TP53,ERBB2,PLXNA1,SYTL4,FANCI,SLC9A7,APOBEC3B,RPS6KA2,TRANK1,PIK3CA,TLN2,TIPARP,CPD,ORAI2,SGCE,AKT1,UTRN,ROR1,IDH1,PLCH1,RBL1,PTK7,AXL,CYP2U1,E2F8,LIFR,HOXC13,PCSK5,NUDT6,NKX3-1,ARHGEF11,CDCA8,CNTNAP2,B4GALT4,DSE,FRY,PTEN,PIK3AP1,ATP5H,FRAS1,TOX2,CD9,PRKG1,ADAM15,IQGAP3,ETV7,RBMS2,MDFI,KCNJ12,RASGRF1,NR3C1,MRS2,LITAF,PPARA,C1GALT1C1,GNA11,PTPRF,MAPKAPK2,SERPINA1,FAT4,FGFR2,CGREF1,NETO2,CSTF2,CABIN1,NR4A2,PLD1,MAP3K5,AFAP1,RUSC1,MELK,ARHGEF4 |
| 3.202e-02 | -3.44 | BTNL8 (butyrophilin-like 8) | protein interactions | 79908 | 42 | 9 | 16036 | 1726 |
TMEM87B,TCTN2,PTK7,ITGA7,ITGA6,NETO2,CACNA2D2,PTGFRN,LEPR |
| 3.204e-02 | -3.44 | CTGAGCC,MIR-24 | MSigDB lists | CTGAGCC,MIR-24 | 222 | 31 | 17758 | 1761 |
AMOTL2,PRSS8,SEMA6B,PHF20L1,CITED4,PTPN9,FURIN,PTGER4,STRADB,SNN,TNFRSF19,SESN1,SFXN5,MAPK8IP1,RASA1,ATP13A2,PTPRF,PLOD2,AMMECR1,REEP1,RAP2C,CDKN1B,YOD1,SP6,C8orf58,PIM1,CLIP2,RARG,TMEM9,CMTM4,SMAGP |
| 3.205e-02 | -3.44 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | MSigDB lists | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | 75 | 13 | 17758 | 1761 |
MAPKAPK2,RPS6KA2,RIPK2,PELI2,RPS6KA1,NFKBIA,NOD2,MAPK11,PELI3,DUSP4,ELK1,FOS,CDK1 |
| 3.205e-02 | -3.44 | MAHAJAN_RESPONSE_TO_IL1A_DN | MSigDB lists | MAHAJAN_RESPONSE_TO_IL1A_DN | 75 | 13 | 17758 | 1761 |
CTGF,PTEN,MITF,RYK,ASAH1,ALDH7A1,COL4A5,EPHB4,CRABP2,FOS,ALDH3A2,LMNA,PLS3 |
| 3.211e-02 | -3.44 | ABBUD_LIF_SIGNALING_1_DN | MSigDB lists | ABBUD_LIF_SIGNALING_1_DN | 25 | 6 | 17758 | 1761 |
OSTF1,SYTL4,ALCAM,S100A4,TSPAN7,ITGA6 |
| 3.211e-02 | -3.44 | LEE_DOUBLE_POLAR_THYMOCYTE | MSigDB lists | LEE_DOUBLE_POLAR_THYMOCYTE | 25 | 6 | 17758 | 1761 |
RMND5A,CYP2U1,MCTP1,LHFPL2,C3orf52,BCL6 |
| 3.211e-02 | -3.44 | LAMELLIPODIUM | MSigDB lists | LAMELLIPODIUM | 25 | 6 | 17758 | 1761 |
FGD6,ARAP3,CTTN,SCYL3,CCDC88A,FGD1 |
| 3.211e-02 | -3.44 | LI_WILMS_TUMOR | MSigDB lists | LI_WILMS_TUMOR | 25 | 6 | 17758 | 1761 |
WASF3,CRABP2,ETV4,COL13A1,HOXA9,FZD7 |
| 3.211e-02 | -3.44 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP | 25 | 6 | 17758 | 1761 |
RUNX3,ENPP1,PARP12,RBM47,GALNT12,ZNF385B |
| 3.211e-02 | -3.44 | CHEOK_RESPONSE_TO_HD_MTX_DN | MSigDB lists | CHEOK_RESPONSE_TO_HD_MTX_DN | 25 | 6 | 17758 | 1761 |
TGIF1,ALDH5A1,ARF6,RALBP1,CNOT8,ARF4 |
| 3.211e-02 | -3.44 | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | MSigDB lists | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | 25 | 6 | 17758 | 1761 |
TWIST1,CD274,TRAF5,IFITM3,PTGES,PLCG2 |
| 3.211e-02 | -3.44 | single organismal cell-cell adhesion | biological process | GO:0016337 | 447 | 58 | 16441 | 1675 |
MYL9,FBLIM1,RUNX2,IL15,BVES,HLA-E,SOX9,RET,TP53,BTN3A1,PKP2,IL18R1,SRPX2,NOV,CDH1,CYR61,NPNT,BMP7,KIF13B,DLG1,BAX,ARVCF,CDH3,PIK3CD,WNT3A,SYK,GCNT1,CYP1B1,CAMSAP3,PODXL2,RHOA,RIPK2,TNIP1,PTPRU,MICB,RC3H2,PTGER4,EZR,SCRIB,VEZT,FNDC3A,MYL12A,FZD7,CDK5R1,FAS,GNAS,DDOST,COL13A1,SEMA4D,PLPP3,ITGA7,ANXA9,ITGAV,ICOSLG,FZD5,F2RL1,HSPB1,L1CAM |
| 3.213e-02 | -3.44 | Class I PI3K signaling events | Pathway Interaction DB | pi3kcipathway | 41 | 11 | 2227 | 331 |
PLCG1,RHOA,ARAP3,PTEN,PIK3R1,PLCG2,PIK3CA,SGK1,YES1,ARF6,TIAM1 |
| 3.213e-02 | -3.44 | CHD3 (chromodomain helicase DNA binding protein 3) | protein interactions | 1107 | 143 | 23 | 16036 | 1726 |
MX1,SIRT1,SMARCA2,PHF20L1,LGR4,NR4A1,SAT1,HABP4,TP53,FAM134A,PSME1,BARD1,MAN2A2,SLC27A6,TSPAN6,PLK4,BCL6,CSTF2,HDAC1,TWIST1,CTTN,LRIF1,METAP2 |
| 3.217e-02 | -3.44 | HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1) | protein interactions | 3320 | 760 | 98 | 16036 | 1726 |
SLC2A4,TRIM2,EPAS1,FOXM1,RALBP1,CAMKK1,RPS6KA1,CUL4B,RET,EPHA4,TP53,TESK2,ERBB2,NANS,GRK6,HDAC6,PRKACA,DDR1,TYMP,PSMD1,RPS6KA2,CDH1,PASK,BCL6,KCNS3,TUBG1,IRF2,IFIT1,LMAN1,CKS2,NLRP4,MAP3K3,SIRT1,AKT1,ACVR1C,AGO4,PRKCQ,SLC25A5,RNF19B,MAP3K6,CDK1,DDOST,JAK1,LIMK1,STK38,AXL,TRAF3IP1,HSPB1,NR3C2,NR2C2,PRKAA2,PINK1,KLHL13,UBASH3B,PSMD10,TGFBR1,FBXO6,PKN1,HERC6,MERTK,AIP,LGALS3BP,FOXP2,IGF1R,ADRBK1,CALD1,MAP3K9,SGK3,DAPK1,SGK1,WWP1,ERBB3,PIM1,ALPK1,HES1,TESK1,NR3C1,CALM1,PPARA,FBXO9,EIF2AK1,SCRIB,YES1,EPHA1,PDIK1L,G2E3,CDK5R1,ACVRL1,DTX4,AURKA,ARRB1,RHOBTB2,MDH1,CDK18,HMGA1,MAP3K5,FBXO27,AHR |
| 3.220e-02 | -3.44 | TTGCWCAAY_V$CEBPB_02 | MSigDB lists | TTGCWCAAY_V$CEBPB_02 | 60 | 11 | 17758 | 1761 |
PITX2,BMF,CITED4,NFKBIE,KLF5,ITPR3,IDH1,DENND2D,TOB1,CKAP4,NRP2 |
| 3.220e-02 | -3.44 | YAATNANRNNNCAG_UNKNOWN | MSigDB lists | YAATNANRNNNCAG_UNKNOWN | 60 | 11 | 17758 | 1761 |
GNAS,FOXP2,PGM1,CD55,PQLC2,FGFR2,CALD1,NUSAP1,RFX5,LDB2,SPTB |
| 3.220e-02 | -3.44 | chr11p11 | MSigDB lists | chr11p11 | 60 | 11 | 17758 | 1761 |
MDK,PTPRJ,CD82,LRP4,MADD,TSPAN18,GYLTL1B,SLC35C1,CRY2,TP53I11,PRDM11 |
| 3.221e-02 | -3.44 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | 265 | 36 | 17758 | 1761 |
EPS8,C5orf30,BCL2L1,RAB6A,PJA2,PDGFB,LBR,SIRPA,TOP2A,WEE1,RNF220,CTGF,UBE2T,FRYL,BUB1,SPRY2,PLK1,SIRT1,TGIF1,ANLN,FNDC3A,KIF11,LHFPL2,STK17B,PSMA4,CDK1,CDK5R1,STK17A,LRRC42,MID1IP1,CORO1C,DCK,NMI,AURKA,HS3ST3B1,UBE2C |
| 3.225e-02 | -3.43 | Ppp1ca (protein phosphatase 1, catalytic subunit, alpha isoform) | protein interactions | 19045 | 3 | 2 | 16036 | 1726 |
TGFBR1,SH3KBP1 |
| 3.225e-02 | -3.43 | GK2 (glycerol kinase 2) | protein interactions | 2712 | 3 | 2 | 16036 | 1726 |
UGP2,TP53 |
| 3.225e-02 | -3.43 | ITPKC (inositol-trisphosphate 3-kinase C) | protein interactions | 80271 | 3 | 2 | 16036 | 1726 |
AURKA,TP53 |
| 3.225e-02 | -3.43 | Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) | protein interactions | 18005 | 3 | 2 | 16036 | 1726 |
PPP1R2,NEK2 |
| 3.225e-02 | -3.43 | GMIP (GEM interacting protein) | protein interactions | 51291 | 3 | 2 | 16036 | 1726 |
RHOA,GEM |
| 3.225e-02 | -3.43 | FAM78A (family with sequence similarity 78, member A) | protein interactions | 286336 | 3 | 2 | 16036 | 1726 |
ADD3,ADD1 |
| 3.225e-02 | -3.43 | SDR9C7 (short chain dehydrogenase/reductase family 9C, member 7) | protein interactions | 121214 | 3 | 2 | 16036 | 1726 |
HSF2,PLK2 |
| 3.225e-02 | -3.43 | PPEF1 (protein phosphatase, EF-hand calcium binding domain 1) | protein interactions | 5475 | 3 | 2 | 16036 | 1726 |
CALM3,CALM1 |
| 3.225e-02 | -3.43 | RPL4P5 (ribosomal protein L4 pseudogene 5) | protein interactions | 158345 | 3 | 2 | 16036 | 1726 |
TRIM9,PRSS23 |
| 3.225e-02 | -3.43 | GYPC (glycophorin C (Gerbich blood group)) | protein interactions | 2995 | 3 | 2 | 16036 | 1726 |
PDIA3,MPP1 |
| 3.225e-02 | -3.43 | GDF15 (growth differentiation factor 15) | protein interactions | 9518 | 3 | 2 | 16036 | 1726 |
GDF15,MDFI |
| 3.225e-02 | -3.43 | SLC2A3 (solute carrier family 2 (facilitated glucose transporter), member 3) | protein interactions | 6515 | 3 | 2 | 16036 | 1726 |
SNTA1,GOLGB1 |
| 3.225e-02 | -3.43 | Sstr2 (somatostatin receptor 2) | protein interactions | 54305 | 3 | 2 | 16036 | 1726 |
SNTA1,DLG3 |
| 3.225e-02 | -3.43 | MASTL (microtubule associated serine/threonine kinase-like) | protein interactions | 84930 | 3 | 2 | 16036 | 1726 |
RPS6KA1,LMNA |
| 3.225e-02 | -3.43 | POMZP3 (POM121 and ZP3 fusion) | protein interactions | 22932 | 3 | 2 | 16036 | 1726 |
BARD1,NMI |
| 3.225e-02 | -3.43 | SLC36A1 (solute carrier family 36 (proton/amino acid symporter), member 1) | protein interactions | 206358 | 3 | 2 | 16036 | 1726 |
PTEN,PTTG1 |
| 3.225e-02 | -3.43 | BBS5 (Bardet-Biedl syndrome 5) | protein interactions | 129880 | 3 | 2 | 16036 | 1726 |
LZTFL1,KLC3 |
| 3.225e-02 | -3.43 | TIGD7 (tigger transposable element derived 7) | protein interactions | 91151 | 3 | 2 | 16036 | 1726 |
UACA,RAB3IL1 |
| 3.225e-02 | -3.43 | BTN3A3 (butyrophilin, subfamily 3, member A3) | protein interactions | 10384 | 3 | 2 | 16036 | 1726 |
BTN3A2,CTSL |
| 3.225e-02 | -3.43 | CYGB (cytoglobin) | protein interactions | 114757 | 3 | 2 | 16036 | 1726 |
SH3KBP1,ATP13A2 |
| 3.225e-02 | -3.43 | SPATC1 (spermatogenesis and centriole associated 1) | protein interactions | 375686 | 3 | 2 | 16036 | 1726 |
TUBG1,CDC20 |
| 3.225e-02 | -3.43 | PPP1R17 (protein phosphatase 1, regulatory subunit 17) | protein interactions | 10842 | 3 | 2 | 16036 | 1726 |
PRKACA,PRKG1 |
| 3.225e-02 | -3.43 | Foxg1 (forkhead box G1) | protein interactions | 15228 | 3 | 2 | 16036 | 1726 |
HDAC1,TLE1 |
| 3.225e-02 | -3.43 | Khdrbs1 (KH domain containing, RNA binding, signal transduction associated 1) | protein interactions | 20218 | 3 | 2 | 16036 | 1726 |
SH3KBP1,RASA1 |
| 3.225e-02 | -3.43 | GMFG (glia maturation factor, gamma) | protein interactions | 9535 | 3 | 2 | 16036 | 1726 |
CAMK1D,VANGL1 |
| 3.225e-02 | -3.43 | Cbl (Casitas B-lineage lymphoma) | protein interactions | 12402 | 3 | 2 | 16036 | 1726 |
SYK,SH3KBP1 |
| 3.225e-02 | -3.43 | C16orf58 (chromosome 16 open reading frame 58) | protein interactions | 64755 | 3 | 2 | 16036 | 1726 |
TGOLN2,LYPD3 |
| 3.225e-02 | -3.43 | H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) | protein interactions | 9563 | 3 | 2 | 16036 | 1726 |
FBXO6,ANTXR1 |
| 3.225e-02 | -3.43 | SIX6 (SIX homeobox 6) | protein interactions | 4990 | 3 | 2 | 16036 | 1726 |
TLE1,AES |
| 3.225e-02 | -3.43 | C1orf52 (chromosome 1 open reading frame 52) | protein interactions | 148423 | 3 | 2 | 16036 | 1726 |
DENND2D,DEF6 |
| 3.225e-02 | -3.43 | Rab33b (RAB33B, member RAS oncogene family) | protein interactions | 19338 | 3 | 2 | 16036 | 1726 |
TGFBR1,CALM1 |
| 3.225e-02 | -3.43 | Rab14 (RAB14, member RAS oncogene family) | protein interactions | 68365 | 3 | 2 | 16036 | 1726 |
TBC1D4,TBC1D1 |
| 3.225e-02 | -3.43 | LARGE (like-glycosyltransferase) | protein interactions | 9215 | 3 | 2 | 16036 | 1726 |
PLAUR,DAG1 |
| 3.225e-02 | -3.43 | MRVI1 (murine retrovirus integration site 1 homolog) | protein interactions | 10335 | 3 | 2 | 16036 | 1726 |
ITPR1,PRKG1 |
| 3.225e-02 | -3.43 | C2orf73 (chromosome 2 open reading frame 73) | protein interactions | 129852 | 3 | 2 | 16036 | 1726 |
HSPB1,SH3BP4 |
| 3.225e-02 | -3.43 | CLYBL (citrate lyase beta like) | protein interactions | 171425 | 3 | 2 | 16036 | 1726 |
INPP5D,SH3KBP1 |
| 3.225e-02 | -3.43 | DPYS (dihydropyrimidinase) | protein interactions | 1807 | 3 | 2 | 16036 | 1726 |
DPYSL5,TMEM41B |
| 3.225e-02 | -3.43 | Tubb5 (tubulin, beta 5 class I) | protein interactions | 29214 | 3 | 2 | 16036 | 1726 |
PRICKLE1,HDAC6 |
| 3.225e-02 | -3.43 | HLA-DOB (major histocompatibility complex, class II, DO beta) | protein interactions | 3112 | 3 | 2 | 16036 | 1726 |
CD63,CD82 |
| 3.225e-02 | -3.43 | Hdac2 (histone deacetylase 2) | protein interactions | 15182 | 3 | 2 | 16036 | 1726 |
THRB,THRA |
| 3.225e-02 | -3.43 | MORC3 (MORC family CW-type zinc finger 3) | protein interactions | 23515 | 3 | 2 | 16036 | 1726 |
ROR1,RAD23A |
| 3.226e-02 | -3.43 | regulation of blood circulation | biological process | GO:1903522 | 233 | 33 | 16441 | 1675 |
SCN5A,GAA,EPAS1,BVES,THRA,CALM3,PKP2,PRKACA,CALM2,SNTA1,ADORA1,ADRBK1,CTGF,ECE1,PDE4D,CACNA1D,F2R,THRB,DOCK4,KCNJ12,RHOA,AKT1,CALM1,PDE5A,PRKCQ,ATP1B1,DOCK5,SP4,KCNMB4,ATP1A1,GPER1,SEMA3A,F2RL1 |
| 3.226e-02 | -3.43 | vesicle localization | biological process | GO:0051648 | 233 | 33 | 16441 | 1675 |
GRN,CTSZ,SYTL4,SYTL2,KIF5B,AP1M2,CTSC,DPYSL2,LMAN1,RAB27B,PACSIN1,SYTL3,PPP6R1,RASGRP1,MYO5A,SEC23A,RAB3B,KIF13A,COL7A1,SCRIB,MCFD2,BBS2,STX3,TRIM9,AP1AR,SERPINA1,SYT7,WIPI1,FGFR2,SYT13,NDE1,SHROOM2,SNPH |
| 3.227e-02 | -3.43 | regulation of lymphocyte activation | biological process | GO:0051249 | 369 | 49 | 16441 | 1675 |
LAMP1,CASP3,LGALS3,IL15,INPP5D,HLA-E,ERBB2,IL27RA,IL18,CD274,PKN1,MERTK,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,PIK3CA,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,RIPK2,AKT1,ITCH,PIK3R1,PDE5A,PRKCQ,YES1,CD40,FAS,SOX13,CD83,IRS2,BANK1,AXL,NOD2,PPP2R3C,ICOSLG,NDFIP1,JAK3,AHR |
| 3.238e-02 | -3.43 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | 155 | 23 | 17758 | 1761 |
ZMAT1,RUNX2,ERMAP,STMN3,RNF182,APC2,TP53INP2,FOS,STX3,CDK5R1,HDAC9,IRF2BPL,ITGB8,CTSC,MAP2,RBL1,SGK3,PGM2L1,ZRANB1,SCARA3,MYT1,PKIA,PARP9 |
| 3.238e-02 | -3.43 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | 155 | 23 | 17758 | 1761 |
UGT8,B3GNT2,IL15RA,SERPINE2,PLAUR,PTPN9,EIF5A2,TMEM170B,DUSP4,PJA2,NUP62CL,TYSND1,ISM1,RGS3,OSBPL3,KCNN4,DRAM1,KLF11,ACSL4,GEM,ICOSLG,MAFF,L1CAM |
| 3.241e-02 | -3.43 | negative regulation of canonical Wnt signaling pathway | biological process | GO:0090090 | 151 | 23 | 16441 | 1675 |
CTHRC1,PSMB4,PSME2,AMER1,SOX9,LRP4,PRICKLE1,PSMD10,AES,PSME1,NPHP3,APC2,PSMA4,FZD6,PPP2R3A,PSMD1,ANKRD6,DACT1,TBX18,NKD1,DAB2IP,WNT3A,DVL2 |
| 3.241e-02 | -3.43 | digestive system development | biological process | GO:0055123 | 151 | 23 | 16441 | 1675 |
EPB41L5,PDGFC,CDKN1C,LGR4,THRA,ITGA6,RET,NCKAP1,SAV1,CCNB1,NPHP3,FOXL1,PDGFA,CYP1A1,FAT4,IGF1R,FGFR2,GATA2,DACT1,MEGF8,KLF5,COBL,PCSK5 |
| 3.242e-02 | -3.43 | Rho GTPase binding | molecular function | GO:0017048 | 81 | 14 | 16491 | 1673 |
DOCK4,RALBP1,IQGAP1,CORO1C,EPS8,TRIOBP,DIAPH2,STRADB,NCKAP1,IQGAP3,PKN1,ITPKA,ARHGEF16,DOCK9 |
| 3.242e-02 | -3.43 | GoLoco | smart domains | SM00390 | 7 | 3 | 9131 | 997 |
GPSM2,RGS14,RAP1GAP |
| 3.242e-02 | -3.43 | GS | smart domains | SM00467 | 7 | 3 | 9131 | 997 |
TGFBR1,ACVRL1,ACVR1C |
| 3.242e-02 | -3.43 | PI3K_rbd | smart domains | SM00144 | 7 | 3 | 9131 | 997 |
PIK3C2B,PIK3CD,PIK3CA |
| 3.245e-02 | -3.43 | HSPA1L (heat shock 70kDa protein 1-like) | protein interactions | 3305 | 113 | 19 | 16036 | 1726 |
SIRT1,SHMT1,FIGNL1,LPGAT1,UBASH3B,CUL4B,CDC20,TP53,CAMK1D,NUCB2,VASH1,HDAC6,MRPS36,DENND2D,EPN3,ALDH3B1,RRBP1,TRAF3IP1,TUBG1 |
| 3.249e-02 | -3.43 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | 180 | 26 | 17758 | 1761 |
CASP3,LCA5,CCDC109B,MFSD2B,TP53,IL18,NOTUM,ALCAM,STX3,SLC9A2,CD83,SOCS3,RASGRP2,PIK3AP1,SPIN4,SGK1,DUSP10,NR4A2,NTN4,KLF9,APOL2,MAFF,CCDC88A,KLF7,JARID2,USP43 |
| 3.249e-02 | -3.43 | GSE3982_BCELL_VS_TH1_UP | MSigDB lists | GSE3982_BCELL_VS_TH1_UP | 180 | 26 | 17758 | 1761 |
ALDH2,REPS2,SYBU,IL27RA,TRMT2B,LOXL2,SLC9A2,ABCD4,CD83,IRS2,DOPEY2,ALDH5A1,CA2,SLC25A4,CTGF,RALGPS2,GNB5,DACT1,SPINT2,OPN3,S100A5,CNPY3,LTA4H,SYK,FARP2,ARHGEF4 |
| 3.249e-02 | -3.43 | GSE3982_DC_VS_BCELL_DN | MSigDB lists | GSE3982_DC_VS_BCELL_DN | 180 | 26 | 17758 | 1761 |
PRODH,GOLIM4,CENPA,FOXJ2,CNOT8,SYBU,TESK2,TCF7,GTF3A,TRIB2,FAM46C,HOXB2,HLA-A,PARM1,GALNT3,WEE1,JAK1,C19orf66,DOLPP1,KIF13B,UBE2J1,SORL1,FAM117A,PIK3C2B,IRF7,RGS14 |
| 3.252e-02 | -3.43 | - | gene3d domains | 1.20.5.120 | 3 | 2 | 9988 | 1080 |
PSME1,PSME2 |
| 3.252e-02 | -3.43 | - | gene3d domains | 4.10.630.10 | 3 | 2 | 9988 | 1080 |
NCOA3,NCOA2 |
| 3.252e-02 | -3.43 | - | gene3d domains | 1.20.1290.10 | 3 | 2 | 9988 | 1080 |
SESN3,SESN1 |
| 3.252e-02 | -3.43 | - | gene3d domains | 4.10.770.10 | 3 | 2 | 9988 | 1080 |
RUNX3,RUNX2 |
| 3.252e-02 | -3.43 | - | gene3d domains | 1.20.120.180 | 3 | 2 | 9988 | 1080 |
PSME1,PSME2 |
| 3.257e-02 | -3.42 | postsynaptic density | cellular component | GO:0014069 | 187 | 27 | 17570 | 1756 |
DLGAP1,CPEB4,EPS8,EPHA4,LRP4,GRIN1,PJA2,GRM5,CDK5R1,NCS1,ADD3,ATP1A1,ADORA1,MAP2,ANKS1B,CABP1,SIPA1L1,ITPR1,NETO2,DLG1,ARRB1,GPER1,RGS14,DLG3,NRGN,LZTS1,RUSC1 |
| 3.260e-02 | -3.42 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | molecular function | GO:0015662 | 31 | 7 | 16491 | 1673 |
ATP1A1,ATP1B3,ATP1B1,ATP7B,ATP2C2,ATP2B1,PCYOX1 |
| 3.260e-02 | -3.42 | insulin receptor binding | molecular function | GO:0005158 | 31 | 7 | 16491 | 1673 |
IRS2,ENPP1,SORBS1,IGF1R,DOK4,PIK3R1,FRS3 |
| 3.261e-02 | -3.42 | MODULE_46 | MSigDB lists | MODULE_46 | 388 | 50 | 17758 | 1761 |
GRN,IL15RA,IL15,HLA-F,DNAJC3,EPS8,SELL,ERBB2,IL18,IL27RA,MGST2,PDGFB,ETS1,EMP2,IL18R1,LGALS3BP,HLA-A,PDGFA,CYR61,CTSC,KCNN4,IL6ST,BCL6,TACSTD2,IFIT1,HLA-C,LAMP3,MX1,CD55,IFITM3,PTGER4,CR2,ARHGDIB,RUNX3,CD40,ALCAM,CDK5R1,EDNRA,FAS,CD83,MDK,HLA-B,SEMA4D,P4HA2,CSF1,NFKBIA,NR4A2,IRF7,GEM,UBE2C |
| 3.262e-02 | -3.42 | USP24 (ubiquitin specific peptidase 24) | protein interactions | 23358 | 12 | 4 | 16036 | 1726 |
ARRB1,DDB2,RP2,LYPD3 |
| 3.262e-02 | -3.42 | GPRIN2 (G protein regulated inducer of neurite outgrowth 2) | protein interactions | 9721 | 12 | 4 | 16036 | 1726 |
PLSCR1,SPRY2,BCAP31,MDFI |
| 3.262e-02 | -3.42 | KIAA1683 (KIAA1683) | protein interactions | 80726 | 12 | 4 | 16036 | 1726 |
CALM2,CALM3,PLSCR1,CALM1 |
| 3.262e-02 | -3.42 | RELT (RELT tumor necrosis factor receptor) | protein interactions | 84957 | 12 | 4 | 16036 | 1726 |
STK39,RELL1,ACOT7,RAB11FIP1 |
| 3.262e-02 | -3.42 | C18orf8 (chromosome 18 open reading frame 8) | protein interactions | 29919 | 12 | 4 | 16036 | 1726 |
SP6,SWAP70,PRPS2,RANBP1 |
| 3.262e-02 | -3.42 | SLC30A7 (solute carrier family 30 (zinc transporter), member 7) | protein interactions | 148867 | 12 | 4 | 16036 | 1726 |
CD40,LYPD3,LYPD6,SPINT2 |
| 3.262e-02 | -3.42 | AGTR2 (angiotensin II receptor, type 2) | protein interactions | 186 | 12 | 4 | 16036 | 1726 |
SNTA1,ERBB2IP,TIMP3,ERBB3 |
| 3.262e-02 | -3.42 | POMGNT2 (protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)) | protein interactions | 84892 | 12 | 4 | 16036 | 1726 |
NRG1,ATP1B3,FBXO6,PLAUR |
| 3.262e-02 | -3.42 | TMF1 (TATA element modulatory factor 1) | protein interactions | 7110 | 12 | 4 | 16036 | 1726 |
PLK1,RAB6A,AP1M2,NR3C1 |
| 3.270e-02 | -3.42 | SLC9A3R1 (solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1) | protein interactions | 9368 | 91 | 16 | 16036 | 1726 |
CLCN3,NF2,TACC1,EZR,PDIA3,YES1,NANS,GRK6,GNA11,PTEN,PHLPP2,PCYOX1,PIK3CA,MDH1,PLCB2,CAPN1 |
| 3.270e-02 | -3.42 | SYNE4 (spectrin repeat containing, nuclear envelope family member 4) | protein interactions | 163183 | 91 | 16 | 16036 | 1726 |
B3GALT6,GOLIM4,TSPAN15,C3orf52,DSE,TMPRSS4,FZD6,KIF5B,TRIM69,PAQR5,FAM20B,KLC3,SARAF,MARCH2,SMCO4,OCLN |
| 3.276e-02 | -3.42 | FA58C_1 | prosite domains | PS01285 | 18 | 5 | 11866 | 1235 |
CNTNAP1,CNTNAP2,DDR1,NRP2,DCBLD1 |
| 3.279e-02 | -3.42 | Amino sugar and nucleotide sugar metabolism | KEGG pathways | ko00520 | 48 | 10 | 6908 | 758 |
GFPT1,PGM1,CMAS,UGP2,UAP1,GNPDA1,CYB5R2,GNE,HEXB,NANS |
| 3.279e-02 | -3.42 | Amino sugar and nucleotide sugar metabolism | KEGG pathways | hsa00520 | 48 | 10 | 6908 | 758 |
GFPT1,PGM1,CMAS,UGP2,UAP1,GNPDA1,CYB5R2,GNE,HEXB,NANS |
| 3.281e-02 | -3.42 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 164 | 24 | 17775 | 1757 |
NCKAP5,RHOA,CPEB4,RUSC2,EPS8,TP53,KIF23,ITPR2,IDH1,S100A2,ADRBK2,SOX13,SOCS3,CDKN2C,PLCG1,PTEN,SLC9A6,TMEM30A,NKD1,PIK3CA,AKR1B1,LIMCH1,EPHB4,SYTL3 |
| 3.284e-02 | -3.42 | GSE17721_LPS_VS_POLYIC_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDM_UP | 197 | 28 | 17758 | 1761 |
PPIF,B3GNT2,GRIN1,DNAJB11,MPP5,RAB38,FNDC3A,SPTLC2,ENDOD1,SNTA1,IGF1R,ETS2,IGSF9,PIK3AP1,PVRL2,SLC44A1,PIK3CA,SFMBT1,STK39,SH3BGRL2,EPHB4,IQGAP3,TSPAN1,PIKFYVE,SGCB,SNX10,AHR,PARP9 |
| 3.284e-02 | -3.42 | GSE30083_SP2_VS_SP3_THYMOCYTE_UP | MSigDB lists | GSE30083_SP2_VS_SP3_THYMOCYTE_UP | 197 | 28 | 17758 | 1761 |
NLRP4,REC8,LASP1,SERPINE2,AK7,PYROXD2,ETV5,LITAF,POMGNT1,ZBTB7B,SNX12,CRISPLD2,SYTL2,CD83,OPTN,ZNF823,ZCCHC12,KCNN4,MFSD2A,GOT1,C2orf72,STK39,NDFIP1,MAST4,NRGN,MED22,MAPK12,FARP2 |
| 3.284e-02 | -3.42 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 197 | 28 | 17758 | 1761 |
ALDH2,ADD1,TBC1D1,DAP,S100A4,TP53,ASAH1,GTF2A2,SEPP1,ERP29,H2AFV,CYP26A1,MAN2A2,ADD3,SIVA1,STK38,PNPLA6,SORL1,ADAM15,SGK1,AHCY,HMGA1,LTA4H,CLIP2,PLCB2,SYK,KDELR1,PCSK5 |
| 3.284e-02 | -3.42 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | 197 | 28 | 17758 | 1761 |
CCNE2,CASP3,NUDT6,DDB2,NF2,EPAS1,MPP1,ITCH,BLVRB,NDC80,PDIA5,GLO1,BLVRA,ICMT,SLC25A5,IDH1,FANCE,CMTM6,ATP6V0B,DNM1L,SIVA1,P4HA2,CENPE,HMGA1,MANF,SGCB,ALDH3A2,MELK |
| 3.284e-02 | -3.42 | chest_wall | COSMIC cancer mutations | chest_wall | 13 | 4 | 17775 | 1757 |
IDH1,RET,PIK3CA,TP53 |
| 3.284e-02 | -3.42 | PRL | COSMIC cancer mutations | PRL | 13 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 3.284e-02 | -3.42 | pituitary-adenoma-PRL | COSMIC cancer mutations | pituitary-adenoma-PRL | 13 | 4 | 17775 | 1757 |
GNAS,CDKN2C,RET,PIK3CA |
| 3.284e-02 | -3.42 | endometrium-ovary-endometriosis | COSMIC cancer mutations | endometrium-ovary-endometriosis | 13 | 4 | 17775 | 1757 |
AKT1,PTEN,PIK3CA,TP53 |
| 3.284e-02 | -3.42 | radius | COSMIC cancer mutations | radius | 13 | 4 | 17775 | 1757 |
GNAS,IDH1,PIK3CA,TP53 |
| 3.285e-02 | -3.42 | V$CACBINDINGPROTEIN_Q6 | MSigDB lists | V$CACBINDINGPROTEIN_Q6 | 231 | 32 | 17758 | 1761 |
LASP1,SLC2A4,CDK17,RALBP1,ITGA6,ARL4C,TP53,RAB6A,PDGFB,SDC1,HPCAL4,SIX4,KCNS3,PIM1,CACNA1D,NCAM1,SMARCA2,FZD4,CBX6,KIF1C,PYGO1,NFIX,RBM47,ACVRL1,ITPR1,NR4A3,ARPC2,C1orf43,NRGN,USF2,AHR,PKIA |
| 3.295e-02 | -3.41 | V$IK3_01 | MSigDB lists | V$IK3_01 | 214 | 30 | 17758 | 1761 |
BCAM,ARAP3,FRMD4A,TSC22D3,RGAG1,CD40,FOS,SRPX2,TIMP3,CYR61,PRICKLE3,NFKBIA,AMMECR1,SLC44A1,MADD,TFAP2A,FAM117A,ADAM15,SNX16,SH3BGRL2,SERPINI1,SP6,TINAGL1,GRAMD1C,ARPC2,WDR62,SEMA3A,MYT1,LIFR,PTGES |
| 3.295e-02 | -3.41 | Calcium signaling pathway | KEGG pathways | ko04020 | 179 | 28 | 6908 | 758 |
PPIF,ORAI2,CALM1,GRIN1,ERBB2,CALM3,ITPR2,ITPR3,PRKACA,SLC25A5,GNA11,GRM5,EDNRA,CALM2,GNAS,PLCG1,SLC25A4,STIM1,PLCG2,ITPR1,GRIN2D,ERBB3,CACNA1D,PHKA2,ITPKA,F2R,PLCB2,ATP2B1 |
| 3.295e-02 | -3.41 | Calcium signaling pathway | KEGG pathways | hsa04020 | 179 | 28 | 6908 | 758 |
PPIF,ORAI2,CALM1,GRIN1,ERBB2,CALM3,ITPR2,ITPR3,PRKACA,SLC25A5,GNA11,GRM5,EDNRA,GNAS,CALM2,PLCG1,SLC25A4,STIM1,PLCG2,ITPR1,GRIN2D,CACNA1D,ERBB3,ITPKA,PHKA2,F2R,PLCB2,ATP2B1 |
| 3.303e-02 | -3.41 | ATGTCAC,MIR-489 | MSigDB lists | ATGTCAC,MIR-489 | 83 | 14 | 17758 | 1761 |
MDM1,PARP12,PRSS23,ITGB8,BMP7,OXR1,OPN3,NR4A3,SGK1,NRG1,PDE4D,TRIB2,SP4,SCN3A |
| 3.309e-02 | -3.41 | regulation of calcium ion transmembrane transporter activity | biological process | GO:1901019 | 66 | 12 | 16441 | 1675 |
CALM2,GNB5,STIM1,CABP1,CALM1,PLCG2,CALM3,PDE4D,ATP1B1,PRKACA,CACNB4,MYO5A |
| 3.309e-02 | -3.41 | nephron tubule morphogenesis | biological process | GO:0072078 | 66 | 12 | 16441 | 1675 |
CTNNBIP1,HES1,FAT4,LGR4,FMN1,NPNT,SOX9,DLG1,TACSTD2,OSR1,SOX8,ADAMTS16 |
| 3.312e-02 | -3.41 | hydrolase activity | molecular function | GO:0016787 | 2416 | 271 | 16491 | 1673 |
GAA,KLK10,SSH1,ATP8A1,HEXB,TAP1,DHX8,LACTB2,DPP8,PSMD1,PALD1,TUBG1,TINAGL1,APOBEC3G,ERAP2,METAP2,SMARCA2,LOC81691,KIFC2,TNIP1,CASP9,CDA,KIF13A,PIF1,F12,POR,ARF4,ENPP1,PLCG1,GDE1,DNM1L,ATP7B,PTER,BMP1,HDAC1,ARF6,DDX58,MRPL44,ALDH6A1,TMEM55B,RAB23,KIF23,KIAA1161,ATG4A,GNS,ATP5H,PPP4R1,PCYOX1,PIKFYVE,PMPCB,KLK5,KIF20A,PRSS23,ATP8B3,PSMA4,GNA11,DCP2,DHX32,PTPRF,MMP15,FAAH,AGBL5,KLK7,IFIH1,ADAMTS16,PLA2G4A,MTM1,DLGAP5,ST14,RALBP1,INPP5D,ATP2C2,PRSS22,TMPRSS4,ZFYVE9,APPBP2,APOBEC3B,ENPP5,PDE4D,LGMN,ARL4D,RAB27B,NAGA,ATG4D,MYO5B,MX1,ENPP4,SSH3,APOBEC3D,CAPN6,PTPN9,KIF1C,RAD17,ATP1B1,RAB38,XRCC6BP1,ATP10D,AMZ2,INPP4B,PNPLA6,TRABD2A,NUDT6,ATP9A,ARL4C,PDIA3,CTSZ,APOBEC3H,PLPPR4,DNAH3,DIRAS3,GNB5,PTEN,CTSC,ARSG,ALG13,KLC3,ADAM15,ATP8B1,CNOT6L,ADAMTS2,OPLAH,LONRF3,FURIN,KIF11,ARSK,GPLD1,ABCB1,PPM1H,ERAP1,CENPE,HMGA1,ARSB,ESPL1,ACOT7,TLL2,CASP3,PPM1J,GNPDA1,CNOT8,VARS2,HDAC6,TSEN34,ABCD4,RAB15,DPYSL2,IMPAD1,PAPL,DLG1,ABCA2,DUSP10,RAB20,MYH14,PTPRE,DDX59,ATL1,USP18,ARFRP1,ARHGDIB,KLK6,TYSND1,RHEB,DPYSL3,EDNRA,MAN2A2,PLCH1,NEIL1,HPSE,DOLPP1,GLA,RAP1GAP,CPPED1,CAPN1,PCSK5,RRAGD,PRSS8,PEX6,UBASH3B,ABCG2,ASAH1,RAB6A,PHLPP1,ADAMTSL4,OTUD1,CA2,KIF13B,AHCY,NCEH1,ZRANB1,PLCB2,DESI2,ABCC1,DPYSL5,PDE5A,AMDHD1,GNAS,NUDT16,PHLPP2,PLPP3,CTSA,YOD1,PLD1,ATP1B3,USP43,DYNLRB1,CTDSPL,HDAC11,MRAS,LPIN3,ATP6V0B,KIF14,PLCG2,GLB1L2,ECE1,MINPP1,CTDSP2,GM2A,SULF2,SIRT1,CPD,GCA,PTPRU,FIGNL1,DUSP4,CASP4,ATP13A2,TAPBP,ATP1A1,IDE,PTPRJ,ABHD12,MMP17,ADAMTS14,LTA4H,ABCA1,NDST3,MAN2B2,GNE,ERI2,NOTUM,NTAN1,SBF1,HDAC9,KIF5B,TOP2A,ADORA1,ALPP,GALNS,GTF2F2,ABCD1,MYO5A,ATP2B1,FAH,RHOA,RAB3B,PSMB4,GUSB,CFAP46,GGH,RNPEP,SCRN2,FUCA1,ENDOD1,CTSL,RND3,PRCP,CTSV,OTUB2,SPCS3,GEM,DIS3L,ABCG1 |
| 3.314e-02 | -3.41 | AMOP | smart domains | SM00723 | 3 | 2 | 9131 | 997 |
SUSD2,ISM1 |
| 3.314e-02 | -3.41 | CADG | smart domains | SM00736 | 3 | 2 | 9131 | 997 |
SGCE,DAG1 |
| 3.314e-02 | -3.41 | PI3K_p85B | smart domains | SM00143 | 3 | 2 | 9131 | 997 |
PIK3CD,PIK3CA |
| 3.319e-02 | -3.41 | Peptidase_M1_N | interpro domains | IPR014782 | 13 | 4 | 18293 | 1814 |
ERAP1,RNPEP,LTA4H,ERAP2 |
| 3.319e-02 | -3.41 | FERM-adjacent | interpro domains | IPR014847 | 13 | 4 | 18293 | 1814 |
EPB41L5,EPB41L4B,EPB41L4A,FARP2 |
| 3.319e-02 | -3.41 | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | MSigDB lists | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | 13 | 4 | 17758 | 1761 |
ARHGDIB,SP100,ARPC2,NQO1 |
| 3.319e-02 | -3.41 | NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 13 | 4 | 17758 | 1761 |
CDKN1B,CDKN2C,NF2,CDKN2D |
| 3.319e-02 | -3.41 | BIOCARTA_RB_PATHWAY | MSigDB lists | BIOCARTA_RB_PATHWAY | 13 | 4 | 17758 | 1761 |
WEE1,MYT1,CDK1,TP53 |
| 3.319e-02 | -3.41 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3 | 13 | 4 | 17758 | 1761 |
CA2,MINPP1,PTEN,NFKBIA |
| 3.319e-02 | -3.41 | LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP | MSigDB lists | LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP | 13 | 4 | 17758 | 1761 |
AURKA,FAM64A,MELK,ACOT7 |
| 3.319e-02 | -3.41 | HO_LIVER_CANCER_VASCULAR_INVASION | MSigDB lists | HO_LIVER_CANCER_VASCULAR_INVASION | 13 | 4 | 17758 | 1761 |
SERPINB6,TRIM8,ZNF687,CA2 |
| 3.319e-02 | -3.41 | BIOCARTA_CACAM_PATHWAY | MSigDB lists | BIOCARTA_CACAM_PATHWAY | 13 | 4 | 17758 | 1761 |
CALM2,CALM3,CAMKK1,CALM1 |
| 3.319e-02 | -3.41 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | 13 | 4 | 17758 | 1761 |
LTBP2,TNIP1,F2RL1,PLAUR |
| 3.319e-02 | -3.41 | STEROID_HORMONE_RECEPTOR_ACTIVITY | MSigDB lists | STEROID_HORMONE_RECEPTOR_ACTIVITY | 13 | 4 | 17758 | 1761 |
NR3C1,NR3C2,NR2C1,NR4A3 |
| 3.319e-02 | -3.41 | chr13q22 | MSigDB lists | chr13q22 | 13 | 4 | 17758 | 1761 |
LMO7,KLF12,BORA,SPRY2 |
| 3.319e-02 | -3.41 | VACUOLAR_PART | MSigDB lists | VACUOLAR_PART | 13 | 4 | 17758 | 1761 |
LAMP2,CD63,LAMP3,ABCA2 |
| 3.319e-02 | -3.41 | SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP | MSigDB lists | SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP | 13 | 4 | 17758 | 1761 |
CCND1,CDKN2C,ING1,CUL4B |
| 3.320e-02 | -3.41 | PTEN_DN.V1_DN | MSigDB lists | PTEN_DN.V1_DN | 172 | 25 | 17758 | 1761 |
SGCE,UGT8,SERPINE2,CDH22,SH3BGRL,ETV5,SELL,CCDC68,CAMK1D,ATP8B3,TSPAN7,HPCAL4,B4GALNT1,PTEN,SEMA4D,CYP4F11,FJX1,INPP4B,TWIST1,ACOX2,NR3C2,NDST3,NEB,TLE6,FARP2 |
| 3.320e-02 | -3.41 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | 172 | 25 | 17758 | 1761 |
ORAI2,LMTK3,FMN1,ZC3H11A,CALM1,CALM3,ERBB2IP,ZFAND5,C11orf95,COL12A1,CALM2,MARCH8,KCNMB4,HPSE,CTSC,SEMA4D,DAPK1,NOD2,BRI3,FAM117A,CTSA,CNPY3,RNF146,DEF6,NR2C2 |
| 3.323e-02 | -3.40 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | 257 | 35 | 17758 | 1761 |
CD99,LTBP1,LGALS3,TRIP10,ITPR2,TIPRL,SLC9A2,ARHGEF10L,RAB15,B3GALNT1,ADRBK1,CABP1,OSBPL3,DUSP10,PHKA2,PLCB2,SGCB,ETV4,TIAM1,MBP,CITED4,CYS1,CBX6,DIAPH2,RUNX3,ONECUT1,DNAJC10,ALDH5A1,MID1IP1,SERPINA1,DNM1L,NR1D2,PLOD3,HOOK1,SEMA3A |
| 3.323e-02 | -3.40 | V$AP2_Q6_01 | MSigDB lists | V$AP2_Q6_01 | 257 | 35 | 17758 | 1761 |
SPRED1,TEX2,OSR2,GRK6,PKN1,PDGFB,HOXB2,NEO1,TFAP4,RNF220,CDK16,ZNRF2,ATP5H,BCL6,CNNM4,DLG3,NCOA2,KCNJ12,C6orf1,TMEM68,CELSR2,MGAT4B,TFAP2C,COL12A1,RASGRP2,PGF,PPP2R5A,SYT7,PTK7,CGREF1,SH3BP4,ADIPOR1,ITPKA,FGD1,RGMA |
| 3.323e-02 | -3.40 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | MSigDB lists | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | 257 | 35 | 17758 | 1761 |
MAN2B2,AVPI1,PINK1,ZNF395,NDRG2,B4GALT4,HDAC6,SH2D4A,CHPF,IER3,CCND1,RCN1,SETDB2,FAM46A,FOSB,PHKA2,PAQR7,LYRM1,OGDHL,CDA,EZR,F12,FOS,ETS2,FAAH,C19orf66,AXL,MFSD2A,SPINT2,SPTBN5,NR4A2,PIEZO1,RAP1GAP,HOOK1,RAB3IL1 |
| 3.327e-02 | -3.40 | hyaluronan metabolic process | biological process | GO:0030212 | 31 | 7 | 16441 | 1675 |
HMMR,PIM1,AKT1,GUSB,IL15,HEXB,CHP1 |
| 3.327e-02 | -3.40 | multi-organism reproductive behavior | biological process | GO:0044705 | 31 | 7 | 16441 | 1675 |
THRB,GRN,APLP2,PTEN,THRA,HEXB,GRIN1 |
| 3.328e-02 | -3.40 | vertebrae | COSMIC cancer mutations | vertebrae | 68 | 12 | 17775 | 1757 |
GNAS,B3GNT7,IFITM3,CTSC,PTEN,OSBPL3,PIK3CA,TP53,FAM81A,IDH1,PLCB2,RUSC1 |
| 3.329e-02 | -3.40 | calcium-dependent protein binding | molecular function | GO:0048306 | 59 | 11 | 16491 | 1673 |
CALM2,ANXA3,KCNIP3,S100A11,S100A4,CABP1,CALM1,CALM3,S100A6,CHP1,C9orf9 |
| 3.336e-02 | -3.40 | REACTOME_BIOLOGICAL_OXIDATIONS | MSigDB lists | REACTOME_BIOLOGICAL_OXIDATIONS | 139 | 21 | 17758 | 1761 |
CYP26B1,OPLAH,GCLM,ALDH2,PAPSS2,UGP2,GCLC,MGST2,GSTP1,CYP4F3,CYP39A1,CYP26A1,CYP1A1,CYP4F11,CYP2S1,NAT1,PAPSS1,AHCY,CYP2U1,SULT2B1,CYP1B1 |
| 3.344e-02 | -3.40 | integrin-mediated signaling pathway | biological process | GO:0007229 | 81 | 14 | 16441 | 1675 |
ITGA3,ITGB8,CTGF,ITGA6,ITGA7,FUT8,ADAM15,TEC,ITGAV,ERBB2IP,FBLN1,BCAR1,SYK,COL16A1 |
| 3.346e-02 | -3.40 | PSMD6 (proteasome 26S subunit, non-ATPase 6) | protein interactions | 9861 | 84 | 15 | 16036 | 1726 |
CCDC92,PSMD1,PSMB4,PSME2,AMFR,TP53,PSMD10,PSME1,ATP1B1,ATP1B3,MCFD2,ZFAND5,PSMA4,PLS3,RAD23A |
| 3.349e-02 | -3.40 | Oncogene Induced Senescence | REACTOME pathways | R-HSA-2559585 | 30 | 7 | 8202 | 867 |
CDKN2C,AGO4,TNRC6C,ETS2,ETS1,CDKN2D,TP53 |
| 3.349e-02 | -3.40 | MAPK targets/ Nuclear events mediated by MAP kinases | REACTOME pathways | R-HSA-450282 | 30 | 7 | 8202 | 867 |
MAPKAPK2,MAPK11,RPS6KA2,DUSP4,ELK1,FOS,RPS6KA1 |
| 3.349e-02 | -3.40 | Ca-dependent events | REACTOME pathways | R-HSA-111996 | 30 | 7 | 8202 | 867 |
CALM2,PLA2G4A,CALM3,PRKAR2B,ADRBK1,PRKACA,CALM1 |
| 3.354e-02 | -3.40 | SESTO_RESPONSE_TO_UV_C2 | MSigDB lists | SESTO_RESPONSE_TO_UV_C2 | 53 | 10 | 17758 | 1761 |
KIF5B,ANXA3,PLSCR1,TRIP10,NR3C1,GCLC,TFAP2A,ERBB3,DUSP4,CTDSP2 |
| 3.354e-02 | -3.40 | LEE_LIVER_CANCER_MYC_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_UP | 53 | 10 | 17758 | 1761 |
PDGFC,RPL12,CTGF,KIF20A,CYR61,HTATIP2,NUSAP1,SNTB1,CDK1,CYP26A1 |
| 3.354e-02 | -3.40 | V$PAX2_01 | MSigDB lists | V$PAX2_01 | 53 | 10 | 17758 | 1761 |
FOXP2,LRRFIP2,ACADSB,RNF128,ANKS1B,HNRNPH2,UBASH3B,CDCA7L,GLA,HDAC9 |
| 3.354e-02 | -3.40 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 53 | 10 | 17758 | 1761 |
SPRED1,GPRC5B,GCLC,PLK2,CORO1C,RRBP1,CITED2,FNDC3A,ARF4,FZD7 |
| 3.354e-02 | -3.40 | VANTVEER_BREAST_CANCER_METASTASIS_UP | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_UP | 53 | 10 | 17758 | 1761 |
ALDH6A1,LYPD6,FUT8,ECI2,RAB27B,MYLIP,MYRIP,ZNF385B,PDIA4,NEO1 |
| 3.354e-02 | -3.40 | chr5q13 | MSigDB lists | chr5q13 | 53 | 10 | 17758 | 1761 |
FAM169A,PIK3R1,HEXB,RAD17,F2R,MRPS36,F2RL1,LHFPL2,RASA1,OCLN |
| 3.354e-02 | -3.40 | Mitochondrial_sb/sol_carrier | interpro domains | IPR018108 | 53 | 10 | 18293 | 1814 |
SLC25A48,SLC25A24,SLC25A4,SLC25A13,SLC25A27,SLC25A30,SLC25A43,SLC25A5,SLC25A38,SLC25A36 |
| 3.354e-02 | -3.40 | Mt_carrier_dom | interpro domains | IPR023395 | 53 | 10 | 18293 | 1814 |
SLC25A48,SLC25A24,SLC25A4,SLC25A13,SLC25A27,SLC25A30,SLC25A43,SLC25A5,SLC25A38,SLC25A36 |
| 3.355e-02 | -3.39 | negative regulation of cell cycle G1/S phase transition | biological process | GO:1902807 | 104 | 17 | 16441 | 1675 |
PSMB4,PSME2,CTDSPL,TP53,PSMD10,PSME1,PSMA4,JADE1,CCND1,SUSD2,E2F7,PSMD1,PTEN,DACT1,CDKN1B,FHL1,CTDSP2 |
| 3.359e-02 | -3.39 | V$AREB6_04 | MSigDB lists | V$AREB6_04 | 240 | 33 | 17758 | 1761 |
LTBP1,BMF,VPS26A,M6PR,CDKN2C,FOXP2,ST5,CTGF,IGF1R,SHC3,LMO4,SLC44A1,FUT8,RFX5,TAGLN2,ERBB3,TGIF1,SMARCA2,PCGF5,RASGRF1,FBLN5,SERTAD4,ATP8B3,H2AFV,NFIX,SWAP70,KLF12,TMC5,AGBL5,KLF5,ARF6,DEF6,KLF7 |
| 3.360e-02 | -3.39 | skin-face-other-keratoacanthoma | COSMIC cancer mutations | skin-face-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | spindle_and_epithelioid | COSMIC cancer mutations | spindle_and_epithelioid | 19 | 5 | 17775 | 1757 |
CDH1,AKT1,PTEN,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-scalp-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-scalp-malignant_melanoma-superficial_spreading | 19 | 5 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA |
| 3.360e-02 | -3.39 | skin-lower_leg-other-keratoacanthoma | COSMIC cancer mutations | skin-lower_leg-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | ependymoma_Grade_III-IV | COSMIC cancer mutations | ependymoma_Grade_III-IV | 19 | 5 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,TP53 |
| 3.360e-02 | -3.39 | genital | COSMIC cancer mutations | genital | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-upper_arm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-upper_arm-carcinoma-squamous_cell_carcinoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-chest-other-keratoacanthoma | COSMIC cancer mutations | skin-chest-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-genital-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-genital-carcinoma-squamous_cell_carcinoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | soft_tissue-fat-liposarcoma-dedifferentiated | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-dedifferentiated | 19 | 5 | 17775 | 1757 |
CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-arm-other-keratoacanthoma | COSMIC cancer mutations | skin-arm-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | gliosarcoma | COSMIC cancer mutations | gliosarcoma | 19 | 5 | 17775 | 1757 |
CDKN2C,IDH1,PTEN,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-back-other-keratoacanthoma | COSMIC cancer mutations | skin-back-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-sole-malignant_melanoma-nodular | COSMIC cancer mutations | skin-sole-malignant_melanoma-nodular | 19 | 5 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA |
| 3.360e-02 | -3.39 | bone-tibia-chondrosarcoma-peripheral | COSMIC cancer mutations | bone-tibia-chondrosarcoma-peripheral | 19 | 5 | 17775 | 1757 |
NDRG2,TMEM170B,IDH1,TRIM69,UTRN |
| 3.360e-02 | -3.39 | skin-upper_leg-other-keratoacanthoma | COSMIC cancer mutations | skin-upper_leg-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | 19 | 5 | 17775 | 1757 |
CDH1,AKT1,PTEN,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-leg-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-leg-carcinoma-squamous_cell_carcinoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | skin-lip-other-keratoacanthoma | COSMIC cancer mutations | skin-lip-other-keratoacanthoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | breast-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | breast-carcinoma-adenoid_cystic_carcinoma | 19 | 5 | 17775 | 1757 |
ERBB2,AKT1,PTEN,RET,PIK3CA |
| 3.360e-02 | -3.39 | skin-chest-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-chest-carcinoma-squamous_cell_carcinoma | 19 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | small_intestine-ileum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-ileum-carcinoma-adenocarcinoma | 19 | 5 | 17775 | 1757 |
GNAS,ERBB2,IDH1,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | malignant_adnexal_tumour | COSMIC cancer mutations | malignant_adnexal_tumour | 19 | 5 | 17775 | 1757 |
AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 3.360e-02 | -3.39 | SH2 | smart domains | SM00252 | 112 | 19 | 9131 | 997 |
INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,BCAR3,PLCG1,TNS3,JAK1,SHC3,RINL,PLCG2,JAK3,SYK,SOCS5 |
| 3.361e-02 | -3.39 | NCOA1 (nuclear receptor coactivator 1) | protein interactions | 8648 | 106 | 18 | 16036 | 1726 |
THRB,NR3C1,NR4A1,THRA,ITCH,PPARA,TP53,FOS,ETS1,SYTL2,CCND1,NCOA3,ETS2,TRIM21,RARG,AHR,NR3C2,NCOA2 |
| 3.367e-02 | -3.39 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | 189 | 27 | 17758 | 1761 |
DDB2,SLC11A2,ADCK5,CTSZ,IL27RA,GRK6,MCFD2,TRIB2,FAM101B,SESN1,RNF19B,CASP4,CYB5A,SCARB2,NEIL1,SESN3,FAAH,SPINT2,CD9,NR4A3,FAM102A,TSPAN13,RAB20,PACSIN1,JAK3,TRAF5,ABCG1 |
| 3.367e-02 | -3.39 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_UP | 189 | 27 | 17758 | 1761 |
REPS2,TBC1D8B,NR3C1,SYBU,CDA,ARL4C,CCDC68,CD40,TNFSF9,CDK5R1,FZD7,GABARAPL1,STK17A,TFAP4,RCN1,RND3,LLGL2,SEMA4D,AMMECR1,PHTF1,KCNS3,DTX4,AOX1,ATRNL1,EPB41L4A,RNF146,PKIA |
| 3.367e-02 | -3.39 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | 189 | 27 | 17758 | 1761 |
CCNI,SYPL1,ING1,TRIP10,PPM1J,THRA,RASSF7,CCDC34,TTC7A,ARHGDIB,BCAR1,GNA11,NRP2,SAC3D1,XKRX,AHRR,UBE2Q2,ITGA3,ITGA7,RPN2,GLA,GEM,REEP4,TRAM1,KDELR1,CYP1B1,GCNT1 |
| 3.367e-02 | -3.39 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_UP | 189 | 27 | 17758 | 1761 |
MX1,ENO2,ADCK3,PSME2,RALBP1,SAT1,HTATIP2,IFIT3,ASB13,MRPS36,ALCAM,MNS1,TNFSF9,CASP4,NR4A3,TFAP2A,AKR1B1,SGK1,NR4A2,PIM1,ECE1,ARL4D,WNT3A,IFIH1,PTGES,SCN3A,CXorf56 |
| 3.367e-02 | -3.39 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_DN | 189 | 27 | 17758 | 1761 |
REC8,CASP3,SLC2A4,TIMP2,CCDC109B,SEC61B,PEX6,MPP1,DDIT4L,DNAJB2,PPARA,SELL,EZR,PKP2,NDRG2,DENND2D,TEAD3,COL12A1,MMP15,ARHGAP24,GALNT3,TMEM54,PRPS2,SPINT2,GAD1,SYTL3,TLL2 |
| 3.367e-02 | -3.39 | GSE360_L_DONOVANI_VS_T_GONDII_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_DC_UP | 189 | 27 | 17758 | 1761 |
GAS2L1,ADAMTS2,MBP,ENO2,INPP5D,LITAF,LDB2,ELK1,SPTLC2,SP4,STX3,CCND1,ALDH3B1,PTK7,FABP6,RUNDC3B,KCNS3,ATRNL1,ABCD1,LIMCH1,HOXB13,ANXA9,NR3C2,PTGES,MYL12B,SMAGP,GM2A |
| 3.367e-02 | -3.39 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | 189 | 27 | 17758 | 1761 |
PLA2G4A,PPIF,ZWINT,SERPINE2,ATP9A,PBK,SDC4,NDC80,CDCA8,NUSAP1,GGH,GTF2A2,PHLDA1,KIF11,CDK1,PDIA4,IER3,TOP2A,DCTN6,CA2,PAPSS1,RAB11FIP1,CAB39,AHCY,ALDH3A2,ACOT7,CKS2 |
| 3.367e-02 | -3.39 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | 189 | 27 | 17758 | 1761 |
SEC23A,AVPI1,MRPS15,ERI2,GLO1,HEATR5A,YES1,MCFD2,CMTM6,CRISPLD2,IER3,CDK5RAP1,HLA-B,ARHGEF19,PVRL2,BHLHB9,LRIG1,TRPC1,GLB1L2,PIM1,PIKFYVE,EGLN3,ARMCX6,DLG3,CTH,ARHGEF4,EHD1 |
| 3.367e-02 | -3.39 | REACTOME_ACTIVATED_TLR4_SIGNALLING | MSigDB lists | REACTOME_ACTIVATED_TLR4_SIGNALLING | 91 | 15 | 17758 | 1761 |
MAPKAPK2,SIGIRR,RPS6KA2,RIPK2,RPS6KA1,PELI2,NFKBIA,NOD2,IRF7,MAPK11,PELI3,DUSP4,ELK1,FOS,CDK1 |
| 3.374e-02 | -3.39 | Proximal tubule bicarbonate reclamation | KEGG pathways | ko04964 | 23 | 6 | 6908 | 758 |
MDH1,ATP1A1,ATP1B3,ATP1B1,CA2,SLC4A4 |
| 3.374e-02 | -3.39 | Proximal tubule bicarbonate reclamation | KEGG pathways | hsa04964 | 23 | 6 | 6908 | 758 |
MDH1,ATP1A1,ATP1B3,ATP1B1,CA2,SLC4A4 |
| 3.378e-02 | -3.39 | Vindesine Action Pathway | SMPDB pathways | SMP00438 | 10 | 4 | 978 | 131 |
RALBP1,ABCB1,ABCC1,TP53 |
| 3.378e-02 | -3.39 | Vincristine Action Pathway | SMPDB pathways | SMP00437 | 10 | 4 | 978 | 131 |
RALBP1,ABCB1,ABCC1,TP53 |
| 3.387e-02 | -3.39 | Metabolism | REACTOME pathways | R-HSA-1430728 | 1691 | 200 | 8202 | 867 |
GAA,ACACB,SLC35D2,TXN,HSPG2,AASS,AK7,CRYM,CPT2,SLC25A13,HEXB,MMADHC,CACNA2D2,PSME1,ITPR2,OAT,SDC1,CHPF,ABCD4,CALM2,TYMP,PSMD1,CYP1A1,CTGF,GRHL1,CYP2S1,PAPSS1,SLC44A1,PIK3CA,AOX1,KCNS3,AKR1B1,PIK3CD,ACOX2,TECR,CYP1B1,CDA,PRKAR2B,SLC25A5,IDH1,CYP4F3,PLCH1,HS6ST1,ENPP1,PLCG1,SLC25A4,AGPAT2,HPSE,BMP1,PIK3C2B,GLA,ITPKA,PRKAA2,FAM213B,ALDH6A1,SLC25A27,ABCG2,ASAH1,CALM3,NDUFA4,ISYNA1,B4GALT4,COX6C,GNS,CA2,ATP5H,BDH1,AHCY,CACNA1D,PIKFYVE,FAR2,PLCB2,NDUFA12,ALDH3A2,NUP85,MCCC2,ABCC1,CYP26B1,CHSY3,FADS2,B3GNT7,PRODH,LPGAT1,CALM1,PDK3,SPTLC2,NUBP1,AMDHD1,GNA11,PSMA4,CYB5A,GLCE,MAPKAPK2,FECH,GNAS,NUDT16,NCOA3,PRKAG2,FAAH,DCK,PLPP3,PRPS2,ITPR1,MDH1,CTSA,PLD1,NUP58,XDH,PLA2G4A,MTM1,SLC2A4,PAPSS2,UGP2,NQO1,PSME2,IQGAP1,INPP5D,MGST2,LPIN3,PRKACA,CYP39A1,CYP26A1,CDS1,CYP4F11,PLCG2,FABP6,GOT1,ACSL4,LGMN,MINPP1,PHKA2,SULT2B1,MED30,GM2A,CTH,CHP1,GPX4,SEC23A,AKT1,PANK1,SAT1,GLO1,ITPR3,COX20,DUOX1,ALDH3B1,CDK19,INPP4B,SLC27A1,CYP2U1,HS3ST3B1,LTA4H,ST3GAL1,NDST3,ABCA1,GCLM,ENO2,BLVRB,SDC4,HAL,PSMD10,DSE,SPR,GSTP1,LBR,TEAD3,ZDHHC21,SGPL1,GNB5,PTEN,ARSG,SLC44A2,ABCD1,ALDH7A1,NCOA2,MED22,FAH,HMMR,B3GALT6,PGM1,OPLAH,ALDH2,SHMT1,B3GNT2,PSMB4,GUSB,GCLC,ELOVL3,PIK3R1,PPARA,BLVRA,ARSK,CPTP,ACADSB,NAT1,ABCB1,ARSB,PTGES,ACOT7,ABCG1 |
| 3.391e-02 | -3.38 | vulva | COSMIC cancer mutations | vulva | 46 | 9 | 17775 | 1757 |
CDKN2C,PLCH1,AKT1,FGFR2,PTEN,PIK3CA,TP53,IDH1,GNA11 |
| 3.391e-02 | -3.38 | endometrium-carcinoma | COSMIC cancer mutations | endometrium-carcinoma | 46 | 9 | 17775 | 1757 |
CDH1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2 |
| 3.400e-02 | -3.38 | ROSS_AML_OF_FAB_M7_TYPE | MSigDB lists | ROSS_AML_OF_FAB_M7_TYPE | 68 | 12 | 17758 | 1761 |
FADS2,CMAS,TIMP3,GATA2,NGFRAP1,PLOD2,DRAP1,SERPINI1,MINPP1,RASA1,BMP2K,NEO1 |
| 3.401e-02 | -3.38 | FG-GAP | interpro domains | IPR013517 | 19 | 5 | 18293 | 1814 |
ITGAV,ITGA3,ITGA7,ITGA6,GPLD1 |
| 3.401e-02 | -3.38 | PAS_fold | interpro domains | IPR013767 | 19 | 5 | 18293 | 1814 |
AHRR,NCOA3,EPAS1,AHR,NCOA2 |
| 3.401e-02 | -3.38 | Int_alpha_beta-p | interpro domains | IPR013519 | 19 | 5 | 18293 | 1814 |
ITGAV,ITGA3,ITGA7,ITGA6,GPLD1 |
| 3.402e-02 | -3.38 | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | MSigDB lists | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | 19 | 5 | 17758 | 1761 |
ATRNL1,CYP26B1,FHL1,MYBL1,METTL7A |
| 3.402e-02 | -3.38 | ZIRN_TRETINOIN_RESPONSE_UP | MSigDB lists | ZIRN_TRETINOIN_RESPONSE_UP | 19 | 5 | 17758 | 1761 |
CTGF,DHRS3,PLAUR,PLK2,RARG |
| 3.402e-02 | -3.38 | GTCAACC,MIR-380-5P | MSigDB lists | GTCAACC,MIR-380-5P | 19 | 5 | 17758 | 1761 |
TRIM2,FRMD4A,KLHL13,FRAS1,CD83 |
| 3.402e-02 | -3.38 | KAMIKUBO_MYELOID_MN1_NETWORK | MSigDB lists | KAMIKUBO_MYELOID_MN1_NETWORK | 19 | 5 | 17758 | 1761 |
GAS2L1,SGK1,TGFBR1,NCKAP1,PGRMC1 |
| 3.402e-02 | -3.38 | CYTOKINESIS | MSigDB lists | CYTOKINESIS | 19 | 5 | 17758 | 1761 |
DIAPH2,NUSAP1,ANLN,SEPT6,RASA1 |
| 3.402e-02 | -3.38 | MODULE_305 | MSigDB lists | MODULE_305 | 19 | 5 | 17758 | 1761 |
MDH1,SHMT1,ALDH2,ALDH3A2,ACO1 |
| 3.402e-02 | -3.38 | NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN | MSigDB lists | NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN | 19 | 5 | 17758 | 1761 |
CCDC68,PRKCQ,CA2,METTL7A,LGALS3BP |
| 3.402e-02 | -3.38 | INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY | MSigDB lists | INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY | 19 | 5 | 17758 | 1761 |
PDIA3,PDIA6,GNPDA1,ERP29,PDIA5 |
| 3.402e-02 | -3.38 | REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 19 | 5 | 17758 | 1761 |
FGD6,ARAP3,ARF6,RALBP1,FGD1 |
| 3.402e-02 | -3.38 | BIOCARTA_NKCELLS_PATHWAY | MSigDB lists | BIOCARTA_NKCELLS_PATHWAY | 19 | 5 | 17758 | 1761 |
IL18,SYK,HLA-A,PIK3R1,PIK3CA |
| 3.402e-02 | -3.38 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | 19 | 5 | 17758 | 1761 |
CASP3,TXN,CCNB1,PTEN,IL6ST |
| 3.402e-02 | -3.38 | AMIT_EGF_RESPONSE_40_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_40_MCF10A | 19 | 5 | 17758 | 1761 |
GNS,BUB1,CYR61,FOS,ZFP36 |
| 3.402e-02 | -3.38 | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | MSigDB lists | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | 19 | 5 | 17758 | 1761 |
TNS3,CTGF,EPAS1,CALD1,L1CAM |
| 3.402e-02 | -3.38 | GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_UP | MSigDB lists | GAVIN_IL2_RESPONSIVE_FOXP3_TARGETS_UP | 19 | 5 | 17758 | 1761 |
SYPL1,CCDC109B,ST14,TMEM173,RRAGD |
| 3.405e-02 | -3.38 | GTPASE_ACTIVITY | MSigDB lists | GTPASE_ACTIVITY | 99 | 16 | 17758 | 1761 |
RAB3B,RHOA,ARL4C,ARFRP1,MRAS,RAB6A,GNA11,RHEB,ARF4,DIRAS3,GNAS,RND3,DNM1L,ARF6,ARL4D,RAB27B |
| 3.405e-02 | -3.38 | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | MSigDB lists | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 99 | 16 | 17758 | 1761 |
PLK1,AKT1,TP53,HMG20B,ELK1,CCNB1,BARD1,CDK1,CCND1,JAK1,LMO4,NFKBIA,NMI,AURKA,HDAC1,TUBG1 |
| 3.407e-02 | -3.38 | CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)) | protein interactions | 8573 | 77 | 14 | 16036 | 1726 |
KCNJ12,IL15RA,PLK2,SNTB2,EPS8,SDC4,DLG1,IL18,F11R,CNTNAP2,ERBB2IP,SDC1,SH2D4A,ARHGEF26 |
| 3.411e-02 | -3.38 | neuron migration | biological process | GO:0001764 | 112 | 18 | 16441 | 1675 |
CELSR2,ASPM,RAPGEF2,DNER,CDK5R1,ITGA3,GATA2,AXL,MATN2,LHX6,PEX2,KIAA0319,BAX,PRKG1,NR4A2,TWIST1,NDE1,SEMA3A |
| 3.419e-02 | -3.38 | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | MSigDB lists | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | 115 | 18 | 17758 | 1761 |
MYL9,CD99,RHOA,PIK3R1,EZR,F11R,BCAR1,MYL12A,ARHGAP35,PLCG1,PLCG2,PIK3CA,CLDN4,MAPK11,PIK3CD,MYL12B,OCLN,MAPK12 |
| 3.432e-02 | -3.37 | Cyclin_N | interpro domains | IPR006671 | 32 | 7 | 18293 | 1814 |
CCNE2,CCNJL,CCNI,CCND1,CCNF,CCNB1,CCNB2 |
| 3.432e-02 | -3.37 | PROTEIN_SECRETION | MSigDB lists | PROTEIN_SECRETION | 32 | 7 | 17758 | 1761 |
LTBP2,CARD8,ARL4D,SCG2,ABCA1,PDIA4,NOD2 |
| 3.432e-02 | -3.37 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN | 32 | 7 | 17758 | 1761 |
SERPINI1,TRAM1,S100A4,S100A6,PTTG1,RASGRP2,RRAGD |
| 3.432e-02 | -3.37 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | 32 | 7 | 17758 | 1761 |
HTATIP2,LHFPL2,STEAP1,GLCE,OPN3,CTH,RRAGD |
| 3.432e-02 | -3.37 | NEMETH_INFLAMMATORY_RESPONSE_LPS_DN | MSigDB lists | NEMETH_INFLAMMATORY_RESPONSE_LPS_DN | 32 | 7 | 17758 | 1761 |
AURKA,MBP,CCNF,H1F0,FOS,LMO4,ABCG1 |
| 3.432e-02 | -3.37 | KASLER_HDAC7_TARGETS_2_DN | MSigDB lists | KASLER_HDAC7_TARGETS_2_DN | 32 | 7 | 17758 | 1761 |
ACOX2,ADD3,CDH22,TNFRSF19,H1F0,ZCCHC24,NFKBIA |
| 3.432e-02 | -3.37 | TSAI_RESPONSE_TO_RADIATION_THERAPY | MSigDB lists | TSAI_RESPONSE_TO_RADIATION_THERAPY | 32 | 7 | 17758 | 1761 |
COL6A2,OAS3,CTGF,CYR61,IFI6,LGALS3BP,COL6A1 |
| 3.432e-02 | -3.37 | PID_WNT_NONCANONICAL_PATHWAY | MSigDB lists | PID_WNT_NONCANONICAL_PATHWAY | 32 | 7 | 17758 | 1761 |
CTHRC1,YES1,RHOA,FZD5,DVL2,FZD7,FZD6 |
| 3.432e-02 | -3.37 | chr6q14 | MSigDB lists | chr6q14 | 32 | 7 | 17758 | 1761 |
CD109,HMGN3,LCA5,FAM46A,ANKRD6,TMEM30A,TBX18 |
| 3.432e-02 | -3.37 | chr4q25 | MSigDB lists | chr4q25 | 32 | 7 | 17758 | 1761 |
PITX2,PDE5A,AP1AR,CYP2U1,CCDC109B,NPNT,PRDM5 |
| 3.432e-02 | -3.37 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | 32 | 7 | 17758 | 1761 |
TP53I11,PRSS23,ITGB8,SGCB,EFNB1,SYK,SOX9 |
| 3.433e-02 | -3.37 | ETS1 (v-ets avian erythroblastosis virus E26 oncogene homolog 1) | protein interactions | 2113 | 56 | 11 | 16036 | 1726 |
APLP2,NCOA3,RUNX2,SP100,EPAS1,ETS2,NR3C1,TP53,HTATIP2,FOS,ETS1 |
| 3.433e-02 | -3.37 | malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | malignant_peripheral_nerve_sheath_tumour | 39 | 8 | 17775 | 1757 |
SS18,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 3.443e-02 | -3.37 | membrane organization | biological process | GO:0061024 | 959 | 115 | 16441 | 1675 |
SUN1,SLC2A4,ATP8A1,TP53,PKP2,F11R,MPP5,FTH1,BCL2L1,SYTL4,CCNB1,EMP2,SPTB,SYTL2,CALM2,RAB15,AP1M2,CDH1,ZDHHC12,REEP1,DLG1,ZDHHC23,SUN3,RPN2,RAB20,LMAN1,ANO4,DLG3,PACSIN1,TRAM1,XKR8,ATG4D,CHP1,PLK1,PPIF,GCA,SEC23A,CLCN3,KCNIP3,SEC61B,MBP,AKT1,SYNE2,EZR,ARFRP1,KIF13A,ATP1B1,RAB38,ICMT,MCFD2,CDK1,ATP10D,OPTN,GABARAPL1,DDOST,DNM1L,SYT13,REEP4,ABCA1,PRKAA2,PACSIN2,TSPAN15,TBC1D1,ATP9A,LRP4,ETV5,CALM3,CTSZ,CNTNAP2,ANO9,LMNA,ATG4A,ZDHHC21,ADORA1,CTSC,PTEN,A4GALT,KCNN4,RPL39,EXOC8,CD9,BAX,ATP8B1,PLEKHF1,PPP6R1,NUP85,SYTL3,CCDC88A,MYO5A,SUN2,RAB3B,PLSCR1,CRB3,RAPGEF2,CALM1,ANO6,COL7A1,ATP8B3,BBS2,STX3,PRKAG2,RPL12,SERPINA1,FAT4,PVRL2,SYT7,TMEM30A,ZDHHC7,ARRB1,GPER1,SPCS3,ATP1B3,TBC1D4,CCNB2,NUP58 |
| 3.447e-02 | -3.37 | RPTOR (regulatory associated protein of MTOR, complex 1) | protein interactions | 57521 | 70 | 13 | 16036 | 1726 |
IRS2,SIRT1,PRKAA2,AKT1,IQGAP1,RPS6KA1,CUL4B,PDIA3,SGK1,EIF4EBP2,CCNB1,RHEB,RRAGD |
| 3.448e-02 | -3.37 | receptor complex | cellular component | GO:0043235 | 325 | 43 | 17570 | 1756 |
SORBS1,ITGA6,EPS8,RET,GABRG2,ERBB2,TGFBR1,IL13RA1,ITPR2,PLXNA1,DDR1,AIP,NRP2,ITGA3,ITGB8,IGF1R,NPNT,IL6ST,DLG1,TRPC1,NOTCH3,ERBB3,DLG3,SYK,ACVR1C,GRIN1,CR2,ROR1,ITPR3,CD40,ALCAM,LEPR,AHRR,GABRD,ABHD12,ITGA7,NETO2,GRIN2D,ITGAV,TRAF5,NR3C2,LIFR,AHR |
| 3.449e-02 | -3.37 | CYCLIN_D1_UP.V1_UP | MSigDB lists | CYCLIN_D1_UP.V1_UP | 181 | 26 | 17758 | 1761 |
BIN1,CASP3,RASGRF1,HSPG2,CPT2,BCL9,RPS6KA1,DCAF7,RASSF7,TAP1,KLK6,MMP15,ETS2,SHC3,CGREF1,GALNS,ABCA2,BMP1,GOT1,HOXB13,FZD5,MYT1,ETV4,ALDH3A2,MGAT5,FGD1 |
| 3.449e-02 | -3.37 | PDGFR-alpha signaling pathway | Pathway Interaction DB | pdgfrapathway | 22 | 7 | 2227 | 331 |
PLCG1,ITGAV,JAK1,ELK1,FOS,PIK3R1,PIK3CA |
| 3.450e-02 | -3.37 | oligodendroglioma_Grade_II | COSMIC cancer mutations | oligodendroglioma_Grade_II | 76 | 13 | 17775 | 1757 |
GNAS,CDKN2C,MUC16,AKT1,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,PLXNA1,IDH1,GNA11 |
| 3.452e-02 | -3.37 | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | MSigDB lists | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | 46 | 9 | 17758 | 1761 |
ITGB8,FOXM1,TFAP2C,ARVCF,COX6C,PDGFB,TOB1,GPX4,SEPHS1 |
| 3.452e-02 | -3.37 | STOSSI_RESPONSE_TO_ESTRADIOL | MSigDB lists | STOSSI_RESPONSE_TO_ESTRADIOL | 46 | 9 | 17758 | 1761 |
PLA2G4A,RASGRF1,ITGA6,RET,LRIG1,NR4A3,ACOX2,SEPP1,SEMA3B |
| 3.455e-02 | -3.37 | BROWN_MYELOID_CELL_DEVELOPMENT_UP | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_UP | 156 | 23 | 17758 | 1761 |
GRN,CPD,LASP1,ARHGEF3,NQO1,S100A11,PLAUR,HEBP1,IQGAP1,SAT1,HEXB,ALCAM,SIRPA,GNS,DOPEY2,SCARB2,SLC6A6,SP100,C10orf54,S100A6,ESYT2,XDH,CD33 |
| 3.455e-02 | -3.37 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | 156 | 23 | 17758 | 1761 |
COL9A3,SORT1,MFI2,RIPK2,PLAUR,ETV5,DIAPH2,COL4A5,FTH1,ZFAND5,STK17B,SIRPA,WWP2,BTG3,H1F0,HOXA9,TSPAN6,REEP1,RAB20,TAGLN2,PDE4D,CACNA1D,SERPINB1 |
| 3.457e-02 | -3.36 | single-organism organelle organization | biological process | GO:1902589 | 2192 | 248 | 16441 | 1675 |
SUN1,SSH1,ADD1,AK7,MRPS15,CUL4B,NDC80,LMCD1,F11R,SYTL4,MORF4L2,CCNB1,HDAC6,FAM101B,CENPN,WEE1,LRRC6,DLG1,PIK3CA,TUBG1,SUN3,RAB20,CTTN,MYH14,PACSIN1,TLN2,DNAAF3,PLK1,SPEF2,CENPA,CELSR2,SPATA18,PBK,MTRF1L,SLC35C1,EZR,ARHGDIB,LOXL2,PIF1,CCNF,ANLN,MCFD2,MRPS36,CDK1,ABR,PRIM1,DZIP1L,KDM4D,DPYSL3,MSL1,WIPI1,DNM1L,MAP2,LIMK1,PLK2,TRAF3IP1,PRDM5,PRKCDBP,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,NR2C2,FGD1,PRKAA2,MRPL44,PEX6,RAB23,KIF23,GPSM2,NCKAP1,SLC1A3,LMNA,ATG4A,FRY,SNX18,RIMS3,TBCD,FAM13B,NEK2,PRKG1,LIMCH1,ALPK1,PPP6R1,SYTL3,CYP26B1,EPB41L5,REC8,DDB2,MRPS33,KIF20A,CORO2A,MYBL2,STRADB,JADE2,ANTXR1,RANBP9,ONECUT1,NCOA3,FAM64A,PVRL2,SETD3,CDCA5,FAM83D,FGD6,AURKA,MDH1,NDE1,ARPC2,SHROOM2,CCNB2,EHD1,GAS2L1,MTM1,SORBS1,SPC25,NF2,TCTN2,DLGAP5,TMSB15A,TRIP10,ACTR8,PTTG1,HDAC11,TP53,PKP2,TESK2,TDRKH,MRAS,NUF2,BCL2L1,STIL,EMP2,MNS1,TMSB15B,SYTL2,PDGFA,TTC21B,SS18,SP100,SETDB2,KIF14,FRYL,PLK4,BCL6,ESPN,EPB41L4B,LMAN1,SNX10,ATG4D,CHP1,CKS2,PPIF,SIRT1,CLCN3,CAMSAP3,SEC23A,CAPN6,FIGNL1,CDC20,SYNE2,CDCA2,NUSAP1,ATP1B1,PYGO1,PKMYT1,ERBB2IP,DAG1,GABARAPL1,NIN,CEP162,JADE1,PDLIM3,SHROOM3,PTK7,CORO1C,PEX2,SIPA1L1,TRIOBP,SPTBN5,SYT13,RGS14,REEP4,PPP2R2D,COBL,TTC8,WASF3,PINK1,PACSIN2,ARHGEF11,KLHL13,POC1B,CIT,EPS8,CDCA8,CTSZ,PKN1,SIX4,HDAC9,SAC3D1,DTX3L,KIF5B,TOP2A,CTSC,LLGL2,PTEN,BAX,BUB1,SPRY2,NCOA2,FARP2,ACBD5,SUN2,RHOA,LCA5,ARHGEF28,ZWINT,TACC1,CFAP46,FMN1,ASPM,UBE2A,STMN3,DIAPH2,COL7A1,BCAR1,KIF11,BBS2,BORA,DCTN6,SWAP70,SERPINA1,RND3,PLOD2,SYT7,ARRB1,PPP2R3C,HMGA1,CENPE,GPER1,GEM,CEP41,WDR62,NCAPG2,UBE2C,WDR45B,ESPL1 |
| 3.465e-02 | -3.36 | response to ketone | biological process | GO:1901654 | 152 | 23 | 16441 | 1675 |
PRKAA2,NKX3-1,AKT1,CALM1,CASP9,CALM3,ERBB2,BCL2L1,ELK1,FOS,SOCS3,FECH,GNAS,TFAP4,CCND1,CALM2,MAP2,FOSB,BAX,AKR1B1,CLDN4,KLF9,HOXB13 |
| 3.470e-02 | -3.36 | Regulation of signaling by CBL | REACTOME pathways | R-HSA-912631 | 18 | 5 | 8202 | 867 |
PIK3CD,YES1,SYK,PIK3R1,PIK3CA |
| 3.472e-02 | -3.36 | CRMP1 (collapsin response mediator protein 1) | protein interactions | 1400 | 99 | 17 | 16036 | 1726 |
ALDH2,RHOA,AMFR,SAT1,GNE,UBE2A,CDCA8,DNAJB11,FTH1,LRRC1,DUSP4,DPYSL3,FAS,SWAP70,DPYSL2,SPRY2,SEPHS1 |
| 3.479e-02 | -3.36 | V$OCT1_03 | MSigDB lists | V$OCT1_03 | 215 | 30 | 17758 | 1761 |
MCTP1,ELK3,CDH22,CHCHD7,COL4A5,MPP5,TP53I11,FGF19,SNX12,ZNF385B,NRP2,NEO1,HDAC9,NFIX,CDKN2C,FOXP2,KLF12,ANKS1B,LMO4,NFKBIA,MITF,NR4A3,PRKG1,LTBP2,GRAMD1C,CITED2,ARSB,SEMA3A,LIFR,RIMS2 |
| 3.479e-02 | -3.36 | V$MEF2_02 | MSigDB lists | V$MEF2_02 | 215 | 30 | 17758 | 1761 |
RASGRF1,SMARCA2,ARAP2,SLC2A4,TIMP2,PLEKHA6,CPEB4,NR4A1,S100A4,NDRG2,ZFAND5,SPTB,PPP2R3A,ZNF385B,HDAC9,DZIP1L,SLC25A4,CTGF,NPNT,COL13A1,RGS3,ITGA7,AMMECR1,RAP2C,SIPA1L1,AKR1B1,TWIST1,ARMCX6,CRTAP,C9orf9 |
| 3.484e-02 | -3.36 | Endocytosis | KEGG pathways | hsa04144 | 258 | 38 | 6908 | 758 |
BIN1,ARAP3,HLA-F,HLA-E,RET,ARFGEF1,TGFBR1,GRK6,MVB12B,FAM21C,VPS26A,SH3KBP1,HLA-A,ZFYVE9,KIF5B,ZFYVE16,ACAP2,ADRBK1,IGF1R,WWP1,HLA-C,ERBB3,F2R,RHOA,ARAP2,ITCH,SNX12,ADRBK2,EPN3,HLA-B,RAB11FIP2,FGFR2,RAB11FIP1,ARRB1,PLD1,ARF6,ARPC2,EHD1 |
| 3.484e-02 | -3.36 | Endocytosis | KEGG pathways | ko04144 | 258 | 38 | 6908 | 758 |
BIN1,ARAP3,HLA-F,HLA-E,RET,ARFGEF1,TGFBR1,GRK6,MVB12B,FAM21C,VPS26A,SH3KBP1,HLA-A,ZFYVE9,KIF5B,ZFYVE16,ACAP2,ADRBK1,IGF1R,WWP1,HLA-C,ERBB3,F2R,RHOA,ARAP2,ITCH,SNX12,ADRBK2,EPN3,HLA-B,RAB11FIP2,FGFR2,RAB11FIP1,ARRB1,PLD1,ARF6,ARPC2,EHD1 |
| 3.486e-02 | -3.36 | nucleoside bisphosphate metabolic process | biological process | GO:0033865 | 38 | 8 | 16441 | 1675 |
ACACB,ENPP1,PAPSS2,PAPSS1,PANK1,SULT2B1,ACOT7,MCCC2 |
| 3.486e-02 | -3.36 | ribonucleoside bisphosphate metabolic process | biological process | GO:0033875 | 38 | 8 | 16441 | 1675 |
ACACB,ENPP1,PAPSS2,PAPSS1,PANK1,SULT2B1,ACOT7,MCCC2 |
| 3.486e-02 | -3.36 | purine nucleoside bisphosphate metabolic process | biological process | GO:0034032 | 38 | 8 | 16441 | 1675 |
ACACB,ENPP1,PAPSS2,PAPSS1,PANK1,SULT2B1,ACOT7,MCCC2 |
| 3.486e-02 | -3.36 | cytokine secretion | biological process | GO:0050663 | 38 | 8 | 16441 | 1675 |
NOD2,BTN3A2,BTN3A1,F2RL1,RNF19B,ABCA1,S100A13,OPTN |
| 3.491e-02 | -3.35 | MHC_I/II-like_Ag-recog | interpro domains | IPR011162 | 39 | 8 | 18293 | 1814 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 3.491e-02 | -3.35 | DELPUECH_FOXO3_TARGETS_DN | MSigDB lists | DELPUECH_FOXO3_TARGETS_DN | 39 | 8 | 17758 | 1761 |
PITX2,ZWINT,FOXM1,H1F0,NEK2,AURKA,NUSAP1,UBE2C |
| 3.491e-02 | -3.35 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS | 39 | 8 | 17758 | 1761 |
CTGF,ITGB8,SOX9,TP53I11,SGCB,SYK,SGPL1,PRDX4 |
| 3.491e-02 | -3.35 | BIOCARTA_P38MAPK_PATHWAY | MSigDB lists | BIOCARTA_P38MAPK_PATHWAY | 39 | 8 | 17758 | 1761 |
MAPKAPK2,PLA2G4A,RAPGEF2,MAP3K9,TGFBR1,ELK1,MAP3K5,HSPB1 |
| 3.491e-02 | -3.35 | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | MSigDB lists | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | 39 | 8 | 17758 | 1761 |
ITGB8,MMP17,EFNA5,EPHB4,DDR1,COL16A1,FGD1,NEO1 |
| 3.491e-02 | -3.35 | FARMER_BREAST_CANCER_CLUSTER_1 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_1 | 39 | 8 | 17758 | 1761 |
MX1,CKAP2,HERC5,OAS3,IFIT1,HERC6,IFIT3,IFI6 |
| 3.491e-02 | -3.35 | PROTEIN_OLIGOMERIZATION | MSigDB lists | PROTEIN_OLIGOMERIZATION | 39 | 8 | 17758 | 1761 |
ALDH5A1,IGF1R,AASS,AMFR,TP53,BAX,NOD2,CDA |
| 3.493e-02 | -3.35 | BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) | protein interactions | 8945 | 335 | 47 | 16036 | 1726 |
CASP3,MRPL44,NFKBIE,DLGAP5,ZNF395,NUAK1,TSPAN15,PTTG1,TP53,TRIB2,PHLPP1,CCNB1,PRKACA,CHPF,ELF3,TFAP4,CCND1,WEE1,ELMO2,DACT1,DLG1,PLK4,CRY2,CTTN,TIAM1,ALDH3A2,ACBD5,SUN2,ALDH2,TACC1,RAPGEF2,CDC20,AMER1,NFE2L1,RGAG1,ERBB2IP,BORA,CDK1,RASA1,TRIM9,NFKBIA,ZNF704,AURKA,TBC1D4,RAP1GAP,HSPB1,FGD1 |
| 3.496e-02 | -3.35 | Nuclear Events (kinase and transcription factor activation) | REACTOME pathways | R-HSA-198725 | 24 | 6 | 8202 | 867 |
MAPKAPK2,MAPK11,RPS6KA2,DUSP4,ELK1,RPS6KA1 |
| 3.497e-02 | -3.35 | cortical cytoskeleton | cellular component | GO:0030863 | 83 | 14 | 17570 | 1756 |
LASP1,SCNN1A,PLEKHH2,CDH1,NF2,LLGL2,MPP1,CALD1,EZR,SPTBN5,CTTN,ANLN,SHROOM2,SPTB |
| 3.498e-02 | -3.35 | positive regulation of alpha-beta T cell activation | biological process | GO:0046635 | 52 | 10 | 16441 | 1675 |
CD55,RHOA,RIPK2,HLA-E,PRKCQ,IL18,SYK,HLA-A,CD83,SOCS5 |
| 3.500e-02 | -3.35 | Breast cancer(PMID:20453838) | GWAS genes | Breast cancer(PMID:20453838) | 7 | 3 | 2389 | 269 |
ZMIZ1,FGFR2,ZNF365 |
| 3.500e-02 | -3.35 | Hippocampal atrophy(PMID:19668339) | GWAS genes | Hippocampal atrophy(PMID:19668339) | 7 | 3 | 2389 | 269 |
EFNA5,MAL2,ARSB |
| 3.500e-02 | -3.35 | Renal function-related traits (sCR)(PMID:22797727) | GWAS genes | Renal function-related traits (sCR)(PMID:22797727) | 7 | 3 | 2389 | 269 |
ALDH2,RGS14,SHROOM3 |
| 3.508e-02 | -3.35 | Nasopharyngeal carcinoma(PMID:20512145) | GWAS genes | Nasopharyngeal carcinoma(PMID:20512145) | 3 | 2 | 2389 | 269 |
TNFRSF19,MECOM |
| 3.508e-02 | -3.35 | Hepatitis C induced liver fibrosis(PMID:22841784) | GWAS genes | Hepatitis C induced liver fibrosis(PMID:22841784) | 3 | 2 | 2389 | 269 |
MERTK,GLT8D2 |
| 3.508e-02 | -3.35 | Attention deficit hyperactivity disorder (time to onset)(PMID:18937294) | GWAS genes | Attention deficit hyperactivity disorder (time to onset)(PMID:18937294) | 3 | 2 | 2389 | 269 |
ADAMTS2,SULF2 |
| 3.508e-02 | -3.35 | Multiple sclerosis(PMID:21654844) | GWAS genes | Multiple sclerosis(PMID:21654844) | 3 | 2 | 2389 | 269 |
TRIM2,POPDC3 |
| 3.508e-02 | -3.35 | Iris characteristics(PMID:21835309) | GWAS genes | Iris characteristics(PMID:21835309) | 3 | 2 | 2389 | 269 |
SEMA3A,TRAF3IP1 |
| 3.512e-02 | -3.35 | negative regulation of cell division | biological process | GO:0051782 | 74 | 13 | 16441 | 1675 |
PLK1,SUSD2,E2F7,RPS6KA2,FGFR2,BMP7,ASPM,PTTG1,CDC20,RGCC,BUB1,UBE2C,E2F8 |
| 3.512e-02 | -3.35 | positive regulation of adaptive immune response | biological process | GO:0002821 | 74 | 13 | 16441 | 1675 |
SIRT1,HLA-B,RIPK2,PVRL2,IL6ST,HLA-E,NOD2,IL27RA,PRKCQ,FZD5,CD40,HLA-A,SOCS5 |
| 3.513e-02 | -3.35 | cell division site | cellular component | GO:0032153 | 53 | 10 | 17570 | 1756 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,PLK4,PKN1,ANLN,ARF6,NDE1 |
| 3.513e-02 | -3.35 | cell division site part | cellular component | GO:0032155 | 53 | 10 | 17570 | 1756 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,PLK4,PKN1,ANLN,ARF6,NDE1 |
| 3.516e-02 | -3.35 | LIN_NPAS4_TARGETS_UP | MSigDB lists | LIN_NPAS4_TARGETS_UP | 148 | 22 | 17758 | 1761 |
PRKAA2,RAB3B,EPAS1,LPGAT1,RNF182,MRAS,C2orf69,NANS,FAM81A,BSDC1,MARCH8,B3GALNT1,LYPD6,MKRN3,KIAA0319,PNPLA6,CDKN1B,SGK1,ZDHHC7,PKIA,ACOT7,SCN3A |
| 3.529e-02 | -3.34 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | 76 | 13 | 17758 | 1761 |
DLGAP1,ATP1A1,ETS2,ZFP36,SLC25A13,CASP9,TGFBR1,HMGA1,LGMN,PTPRE,AHR,IER3,M6PR |
| 3.529e-02 | -3.34 | autonomic nervous system development | biological process | GO:0048483 | 45 | 9 | 16441 | 1675 |
HES1,RET,TFAP2A,ERBB2,SOX8,SEMA3A,HOXB2,NRP2,EDNRA |
| 3.529e-02 | -3.34 | embryonic cranial skeleton morphogenesis | biological process | GO:0048701 | 45 | 9 | 16441 | 1675 |
GNAS,SPEF2,RUNX2,GRHL2,FGFR2,TFAP2A,TWIST1,TGFBR1,SIX4 |
| 3.533e-02 | -3.34 | Signaling pathways regulating pluripotency of stem cells | KEGG pathways | hsa04550 | 142 | 23 | 6908 | 758 |
PCGF5,AKT1,FZD4,ACVR1C,PIK3R1,APC2,FZD7,FZD6,ONECUT1,JAK1,IGF1R,FGFR2,IL6ST,PIK3CA,MAPK11,PIK3CD,WNT3A,FZD5,JAK3,LIFR,DVL2,JARID2,MAPK12 |
| 3.533e-02 | -3.34 | Signaling pathways regulating pluripotency of stem cells | KEGG pathways | ko04550 | 142 | 23 | 6908 | 758 |
PCGF5,AKT1,FZD4,ACVR1C,PIK3R1,APC2,FZD7,FZD6,ONECUT1,JAK1,IGF1R,FGFR2,IL6ST,PIK3CA,MAPK11,PIK3CD,WNT3A,FZD5,JAK3,LIFR,DVL2,JARID2,MAPK12 |
| 3.535e-02 | -3.34 | human chr15q24.2 | chromosome location | human chr15q24.2 | 26 | 5 | 26250 | 1887 |
RASGRF1,UBE2Q2,NEIL1,C15orf39,PTPN9 |
| 3.535e-02 | -3.34 | human chr2p25.1 | chromosome location | human chr2p25.1 | 26 | 5 | 26250 | 1887 |
PQLC3,PDIA6,GRHL1,CYS1,LOC101929567 |
| 3.555e-02 | -3.34 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1763 | 202 | 16441 | 1675 |
LGR4,EPAS1,DNAJC3,HEXB,RET,ARFGEF1,MORF4L2,CAMK1D,PDGFB,CALM2,EPCAM,HSF2,GRHL1,NPNT,IL31RA,MITF,FOSB,PASK,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,POR,ARF4,EDNRA,AHRR,MDK,MID1IP1,KLF12,NOD2,HDAC1,HSPB1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,CALM3,PSIP1,LMNA,MECOM,ELF3,TFAP4,IGF1R,CYR61,GATA2,NEK2,MDFIC,MYDGF,WNT3A,NUP85,GPR161,ELK3,RGMB,SALL4,STAT4,CALM1,PYM1,MYBL2,ELK1,TP53INP2,NFIB,PLIN5,GNAS,MAPKAPK2,ONECUT1,NCOA3,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,SORBS1,ARMCX3,GRHL2,UPF3B,FOXM1,IL15,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,PDGFA,SS18,CDH1,SP100,LMO4,CDH3,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CHP1,CTH,SIRT1,TIMP2,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,IRS2,JADE1,RBL1,WFS1,KLF5,NRG1,IRF7,ABCA1,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,PARM1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,CST3,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,SYK,TRIM62,NCOA2,NFE2L3,PDGFC,HES1,RHOA,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,EIF5A2,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,GPLD1,PITX2,FGFR2,NR1D2,ACVRL1,NR4A3,ARRB1,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 3.555e-02 | -3.34 | proteolysis | biological process | GO:0006508 | 1143 | 135 | 16441 | 1675 |
CASP3,KLK10,DNAJC3,CUL4B,RET,FBXO2,PSME1,CCNB1,DPP8,HDAC6,PSMD1,TINAGL1,ERAP2,METAP2,PLK1,FBXL16,TNIP1,ITCH,USP18,CASP9,KLK6,F12,CCNF,RNF19B,TYSND1,CDK1,TRIM9,BMP1,CAPN1,PCSK5,PRSS8,DNAJB2,ADAMTSL4,ATG4A,OTUD1,NEK2,PCYOX1,ZRANB1,MYLIP,DESI2,PMPCB,KLK5,PRSS23,TP53INP2,PSMA4,FAS,MMP15,NUDT16,AGBL5,AURKA,YOD1,CTSA,KLK7,RNF146,XDH,ADAMTS16,USP43,ST14,PSME2,PTTG1,PRSS22,MVB12B,TMPRSS4,ZFYVE9,RAD23A,KIF14,CDKN1B,ECE1,LGMN,EGLN3,F2R,ATG4D,SIRT1,CPD,GCA,ERLEC1,SEC61B,CAPN6,CDC20,SLC11A2,PRKCQ,XRCC6BP1,DAG1,CASP4,AMZ2,DNAJC10,IDE,NGFRAP1,WFS1,MMP17,TRABD2A,ADAMTS14,LTA4H,NKX3-1,PCOLCE,PINK1,CIT,DAP,PSMD10,PDIA3,CTSZ,FBXO6,DNAJB9,WWP2,CARD8,RNF128,CTSC,ALG13,UBE2J1,BAX,ADAM15,WWP1,ADAMTS2,PSMB4,LONRF3,CFAP46,AMFR,NUB1,FURIN,UBE2A,FBXO9,GGH,RNPEP,SCRN2,CTSL,PRCP,CTSV,ERAP1,ARRB1,OTUB2,SPCS3,UBE2C,NDFIP1,ESPL1,TLL2 |
| 3.565e-02 | -3.33 | HSPD1 (heat shock 60kDa protein 1 (chaperonin)) | protein interactions | 3329 | 191 | 29 | 16036 | 1726 |
SIRT1,CASP3,PACSIN2,ALDH2,CEP70,TTC39B,LGR4,NR3C1,AMFR,CASP9,CDC20,ASB9,RGS20,PDIA3,FBXO6,PRKACA,LGALS3BP,RASA1,SCARB2,CA2,ITGA3,CDH1,BAX,TUBG1,AURKA,HDAC1,PLOD3,CXorf56,MCCC2 |
| 3.567e-02 | -3.33 | EGF-like_dom | interpro domains | IPR000742 | 224 | 31 | 18293 | 1814 |
LTBP1,FBLN5,HSPG2,CELSR2,LRP4,SELL,NRG2,CNTNAP2,F12,DNER,FBLN1,LTBP3,CNTNAP1,FAT4,MUC4,ITGB8,NPNT,VASN,MEGF8,FRAS1,MATN2,BMP1,SORL1,ATRNL1,ADAM15,EGFL7,NRG1,LTBP2,NOTCH3,PCSK5,TLL2 |
| 3.568e-02 | -3.33 | GSE17721_CTRL_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_4H_BMDM_UP | 190 | 27 | 17758 | 1761 |
FBLIM1,MRPL44,GUSB,RALBP1,ARMC7,KIF1C,NDUFA4,MRAS,FAM198B,NPC2,CDK1,BCAP31,ELF3,MSL1,SLC25A4,BDH1,LHX6,NR4A3,TMEM51,IQGAP3,TECR,PLIN3,CCNB2,MYT1,TIAM1,ALDH3A2,GCNT1 |
| 3.568e-02 | -3.33 | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | 190 | 27 | 17758 | 1761 |
MCTP1,MOSPD2,HJURP,BLVRB,NDC80,CCDC34,COL18A1,NENF,SLC36A4,ANLN,RANBP9,PIK3AP1,MFSD2A,KIF14,TSPAN6,PEX2,REEP1,AGBL5,TUBG1,HDAC1,MDH1,RPN2,MANF,FBXO27,NDE1,PPP6R1,MYO5A |
| 3.568e-02 | -3.33 | GSE17721_0.5H_VS_8H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDM_DN | 190 | 27 | 17758 | 1761 |
ENPP4,GFPT1,ARAP2,ELK3,ENO2,IL15,TESK1,TBC1D1,HLA-E,USP18,LYRM1,EPHA4,TAP1,AK4,PSMD10,F11R,MPP5,RAD17,ASB13,GRHL1,LMO4,TBX18,FAM20B,ABCB1,PPP2R3C,RGS14,ABCA1 |
| 3.568e-02 | -3.33 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDM_UP | 190 | 27 | 17758 | 1761 |
SIRT1,PHF20L1,TSPAN15,BVES,NUB1,SDC4,RAB38,SPTLC2,CASP4,PSIP1,LGALS3BP,ARF4,APPBP2,TAF1B,GRHL1,PLOD2,FAAH,CSF1,TMEM30A,TRIOBP,ABCB1,TSPAN13,PIK3CD,NPTXR,RGS14,PLOD3,RBMS2 |
| 3.568e-02 | -3.33 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | 190 | 27 | 17758 | 1761 |
ENPP4,ERMAP,GRHL2,CD63,GABRG2,DHX8,PSMD10,RAB38,LDB2,GABRD,ARTN,JAK1,CTSC,METTL7A,RGS3,PLCG2,SECTM1,RAB11FIP1,DRAM1,FGD6,PLEKHF1,GOT1,CRY2,NCAM1,PTPRE,F2R,APOBEC3G |
| 3.568e-02 | -3.33 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 190 | 27 | 17758 | 1761 |
BIN1,SYPL1,GCA,SLC25A24,CCDC109B,INPP5D,CNOT8,CR2,SNN,DPP8,MYL12A,TIPRL,RASGRP2,SGPL1,SWAP70,FRY,STK38,SORL1,CLMN,RFX5,PIK3CD,PIKFYVE,TBC1D4,CDKN2D,MYLIP,SNX10,MYL12B |
| 3.568e-02 | -3.33 | GSE27786_LSK_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LSK_VS_ERYTHROBLAST_UP | 190 | 27 | 17758 | 1761 |
MTM1,NUDT6,DYNLRB1,ARHGEF3,IL15,ST14,AK4,KIF1C,FBXO6,POMGNT1,ARSK,MUM1L1,APPBP2,RASGRP2,SLC25A36,DCTN6,SESN3,TAF1B,PIK3AP1,EFR3A,CORO1C,MATN2,DBI,TRAF3IP1,PHKA2,DLG3,C12orf75 |
| 3.568e-02 | -3.33 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | 190 | 27 | 17758 | 1761 |
NFE2L3,NUDT6,PTTG1,C1GALT1C1,CCDC34,PIF1,GSTP1,SLC25A43,RNPEP,PRDX4,PRIM1,LRRC42,OSBPL3,BDH1,FAM83D,AURKA,ECI2,MRPS28,ATP1B3,EGLN3,FAR2,ARF6,C12orf75,APOBEC3G,IGSF3,FAH,SEPHS1 |
| 3.568e-02 | -3.33 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | 190 | 27 | 17758 | 1761 |
NR3C1,FRMD6,USP18,PLAUR,RC3H2,STMN3,KCTD12,YES1,NPC2,CYB5A,PRX,GLCE,SLC25A36,EPCAM,APLP2,MDM1,DDOST,DCK,NAT1,LMO4,LRIG1,FUT8,PGRMC1,SGK1,BUB1,HOXB13,NRGN |
| 3.571e-02 | -3.33 | protein dimerization activity | molecular function | GO:0046983 | 1148 | 135 | 16491 | 1673 |
ADD1,EPAS1,CRYM,HEXB,TAP1,PDGFB,SLC8B1,ERP29,BARD1,SPTB,SLC9A7,HSF2,IL6ST,CABP1,ALDH1A3,MITF,ANO4,PTPRE,S100A13,APOBEC3G,SMAGP,RASGRP1,CENPA,TRIM8,ASCL5,CDA,CR2,TFAP2C,PRKRA,IDH1,TP53I3,AHRR,TRIM9,ENPP1,HPSE,DNM1L,LIMK1,ADIPOR1,GLA,RAP1GAP,E2F8,NR2C2,RRAGD,SOX9,ABCG2,HES2,ANO1,MECOM,TFAP4,ITGA3,BHLHE41,FLRT3,MAP3K9,ZMYM1,CCDC88A,ANO6,HMG20B,EIF2AK1,NCOA3,NUDT16,PVRL2,DCK,CSF1,PRPS2,S100A5,NR4A2,MAP3K5,NRBP1,TMEM173,XDH,S100A11,THRA,TP53,ERBB2,BCL2L1,PDGFA,SP100,SRR,TWIST1,DAB2IP,ECE1,NAGA,NR2C1,SEPHS1,CLCN3,GCA,RIPK2,FZD4,DRAP1,GTF2A2,H2AFV,ALDH5A1,IDE,STK26,BHLHB9,AXL,SLC27A1,SPTBN5,ANXA9,LIFR,GCLM,LRP4,TOP2A,FOXP2,CARD8,ADORA1,MYCL,TFAP2A,BAX,ABCD1,ERBB3,NCOA2,S100A6,PVRL4,HES1,PDGFC,FBLN5,SHMT1,GCLC,NR4A1,PIK3R1,GRIN1,NADK2,PRDX4,PITX2,RAB11FIP2,FGFR2,TBX18,DBI,NR4A3,SOX8,USF2,AHR,ACOT7,ABCG1 |
| 3.573e-02 | -3.33 | S100 protein binding | molecular function | GO:0044548 | 13 | 4 | 16491 | 1673 |
EZR,S100A11,IQGAP1,S100A6 |
| 3.573e-02 | -3.33 | long-chain fatty acid-CoA ligase activity | molecular function | GO:0004467 | 13 | 4 | 16491 | 1673 |
SLC27A1,ACSL4,SLC27A6,SLC27A3 |
| 3.577e-02 | -3.33 | Interleukin-11 Signaling Pathway | WikiPathways | WP2332 | 40 | 9 | 4455 | 516 |
PIAS3,RUNX2,AKT1,JAK1,IL6ST,RPS6KA1,PIK3R1,YES1,SOCS3 |
| 3.590e-02 | -3.33 | YRCCAKNNGNCGC_UNKNOWN | MSigDB lists | YRCCAKNNGNCGC_UNKNOWN | 61 | 11 | 17758 | 1761 |
GNAS,FUCA1,PTPRF,HES1,TSC22D3,DUSP10,FZD5,PTPRE,GAD1,PSIP1,FRS3 |
| 3.590e-02 | -3.33 | MODULE_418 | MSigDB lists | MODULE_418 | 61 | 11 | 17758 | 1761 |
DPYSL5,GCA,AVPI1,PCDH1,SECTM1,TACSTD2,RUNX3,ANXA9,SYT13,RAP1GAP,SEMA3B |
| 3.593e-02 | -3.33 | CREBBP (CREB binding protein) | protein interactions | 1387 | 352 | 49 | 16036 | 1726 |
RUNX2,HOXB7,EPAS1,FOXM1,TRIP10,THRA,RPS6KA1,PTTG1,SOX9,TP53,ETS1,HOXB2,ELF3,MECOM,RAD23A,CCND1,RPS6KA2,CDH1,ZCCHC12,FOSB,BCL6,CITED2,MYBL1,NCOA2,SMARCA2,ING1,AKT1,NR3C1,STAT4,CDC20,SERTAD3,MYBL2,MAML2,ELK1,FOS,TXNDC11,PIAS3,NCOA3,ONECUT1,HLF,ETS2,HOXA9,HDAC1,KLF5,IRF7,HMGA1,FHL1,MAP3K5,ABCA1 |
| 3.605e-02 | -3.32 | stereocilium bundle | cellular component | GO:0032421 | 46 | 9 | 17570 | 1756 |
DOCK4,TPRN,MPP1,EPS8,ATP8B1,ESPN,VEZT,TMC1,PLS3 |
| 3.605e-02 | -3.32 | chondroitin sulfate biosynthetic process | biological process | GO:0030206 | 25 | 6 | 16441 | 1675 |
B3GALT6,CHSY3,DSE,XYLT2,XYLT1,CHPF |
| 3.605e-02 | -3.32 | prostate gland epithelium morphogenesis | biological process | GO:0060740 | 25 | 6 | 16441 | 1675 |
HOXB13,NKX3-1,IGF1R,FGFR2,RARG,SOX9 |
| 3.605e-02 | -3.32 | negative regulation of axon extension involved in axon guidance | biological process | GO:0048843 | 25 | 6 | 16441 | 1675 |
SEMA6B,SEMA3G,WNT3A,SEMA4D,SEMA3A,SEMA3B |
| 3.605e-02 | -3.32 | negative regulation of dendrite development | biological process | GO:2000171 | 25 | 6 | 16441 | 1675 |
ARF6,PTEN,CIT,PLK2,RAPGEF2,KIAA0319 |
| 3.605e-02 | -3.32 | left/right pattern formation | biological process | GO:0060972 | 25 | 6 | 16441 | 1675 |
EPB41L5,PITX2,SETDB2,CITED2,MNS1,MEGF8 |
| 3.605e-02 | -3.32 | positive regulation of tissue remodeling | biological process | GO:0034105 | 25 | 6 | 16441 | 1675 |
IL18,TMEM64,CA2,IL15,SYK,BAX |
| 3.605e-02 | -3.32 | B cell homeostasis | biological process | GO:0001782 | 25 | 6 | 16441 | 1675 |
PPP2R3C,CASP3,PIK3CD,PKN1,RC3H2,BAX |
| 3.614e-02 | -3.32 | human chr8q12.1 | chromosome location | human chr8q12.1 | 18 | 4 | 26250 | 1887 |
TMEM68,CA8,CHCHD7,IMPAD1 |
| 3.614e-02 | -3.32 | human chr5q13 | chromosome location | human chr5q13 | 18 | 4 | 26250 | 1887 |
RAD17,F2R,F2RL1,HEXB |
| 3.614e-02 | -3.32 | human chr10q26 | chromosome location | human chr10q26 | 18 | 4 | 26250 | 1887 |
ATRNL1,OAT,PTPRE,FGFR2 |
| 3.614e-02 | -3.32 | human chr20q13.3 | chromosome location | human chr20q13.3 | 18 | 4 | 26250 | 1887 |
STMN3,GNAS,COL9A3,ARFRP1 |
| 3.615e-02 | -3.32 | human chr1p34.2 | chromosome location | human chr1p34.2 | 44 | 7 | 26250 | 1887 |
SVBP,FOXO6,ERMAP,MYCL,MFSD2A,RIMS3,HPCAL4 |
| 3.615e-02 | -3.32 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 84 | 14 | 17758 | 1761 |
DOCK4,ARAP2,ACAP2,IGF1R,SP100,PTEN,DLG1,ATP8B1,SFMBT1,WWP1,MPHOSPH9,HOXB2,ABCC1,DOCK9 |
| 3.620e-02 | -3.32 | NRL_DN.V1_UP | MSigDB lists | NRL_DN.V1_UP | 132 | 20 | 17758 | 1761 |
PCOLCE,SNTB2,PPARA,PDIA5,NUF2,GALNT7,GPSM2,GRTP1,DHRS3,APC2,STK17B,SNTA1,AHRR,LLGL2,KCNN4,SLC16A6,TRPC1,SCN2A,FAIM,ST3GAL1 |
| 3.620e-02 | -3.32 | RB_DN.V1_UP | MSigDB lists | RB_DN.V1_UP | 132 | 20 | 17758 | 1761 |
CCNE2,GCLM,HES1,PLEKHA6,FAM92A1,THRA,DDIT4L,LYNX1,NANS,ARHGEF40,TNFSF9,PRIM1,TMEM54,UBE2T,ARTN,SIVA1,ALPK3,TUBG1,AHCY,SULF2 |
| 3.620e-02 | -3.32 | XU_GH1_AUTOCRINE_TARGETS_DN | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_DN | 132 | 20 | 17758 | 1761 |
CIT,COL12A1,RAVER2,TMEM164,TIMP3,CA2,JAK1,HPSE,NAT1,PLK2,PIK3CA,NETO2,FAM102A,EFNA5,ESPN,SLC39A10,HOOK1,ISOC1,GPX4,SULF2 |
| 3.622e-02 | -3.32 | glycosylceramide metabolic process | biological process | GO:0006677 | 13 | 4 | 16441 | 1675 |
ALDH5A1,GLA,UGT8,NAGA |
| 3.622e-02 | -3.32 | establishment or maintenance of transmembrane electrochemical gradient | biological process | GO:0010248 | 13 | 4 | 16441 | 1675 |
ATP1A1,ATP1B1,ATP1B3,BAX |
| 3.622e-02 | -3.32 | neuroblast division | biological process | GO:0055057 | 13 | 4 | 16441 | 1675 |
WNT3A,FGFR2,ASPM,TEAD3 |
| 3.622e-02 | -3.32 | amino-acid betaine transport | biological process | GO:0015838 | 13 | 4 | 16441 | 1675 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 3.622e-02 | -3.32 | negative regulation of leukocyte mediated cytotoxicity | biological process | GO:0001911 | 13 | 4 | 16441 | 1675 |
HLA-B,HLA-E,HLA-A,TAP1 |
| 3.622e-02 | -3.32 | regulation of retrograde protein transport, ER to cytosol | biological process | GO:1904152 | 13 | 4 | 16441 | 1675 |
YOD1,ERLEC1,BCAP31,UBE2J1 |
| 3.622e-02 | -3.32 | glutathione biosynthetic process | biological process | GO:0006750 | 13 | 4 | 16441 | 1675 |
OPLAH,GCLM,MGST2,GCLC |
| 3.622e-02 | -3.32 | glycolipid catabolic process | biological process | GO:0019377 | 13 | 4 | 16441 | 1675 |
GLA,NAGA,GM2A,HEXB |
| 3.622e-02 | -3.32 | regulation of cholesterol storage | biological process | GO:0010885 | 13 | 4 | 16441 | 1675 |
ABCA1,ABCG1,PPARA,EHD1 |
| 3.622e-02 | -3.32 | positive regulation of interleukin-17 production | biological process | GO:0032740 | 13 | 4 | 16441 | 1675 |
IL18,PRKCQ,IL15,NOD2 |
| 3.622e-02 | -3.32 | neuronal stem cell division | biological process | GO:0036445 | 13 | 4 | 16441 | 1675 |
WNT3A,FGFR2,ASPM,TEAD3 |
| 3.622e-02 | -3.32 | natural killer cell differentiation | biological process | GO:0001779 | 13 | 4 | 16441 | 1675 |
PIK3CD,IL15,MERTK,AXL |
| 3.622e-02 | -3.32 | carnitine transport | biological process | GO:0015879 | 13 | 4 | 16441 | 1675 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 3.622e-02 | -3.32 | positive regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032725 | 13 | 4 | 16441 | 1675 |
DDX58,IL18,SYK,RASGRP1 |
| 3.622e-02 | -3.32 | cell migration involved in heart development | biological process | GO:0060973 | 13 | 4 | 16441 | 1675 |
PITX2,TWIST1,BVES,FLRT3 |
| 3.622e-02 | -3.32 | apical protein localization | biological process | GO:0045176 | 13 | 4 | 16441 | 1675 |
NCKAP1,SHROOM2,SHROOM3,ARF4 |
| 3.622e-02 | -3.32 | cell communication by electrical coupling involved in cardiac conduction | biological process | GO:0086064 | 13 | 4 | 16441 | 1675 |
PKP2,ATP1A1,ATP1B1,PRKACA |
| 3.622e-02 | -3.32 | regulation of cAMP-dependent protein kinase activity | biological process | GO:2000479 | 13 | 4 | 16441 | 1675 |
SIRT1,PRKAR2B,RAPGEF2,PKIA |
| 3.622e-02 | -3.32 | regulation of glomerulus development | biological process | GO:0090192 | 13 | 4 | 16441 | 1675 |
PDGFA,PDGFB,BMP7,RET |
| 3.622e-02 | -3.32 | protein autoprocessing | biological process | GO:0016540 | 13 | 4 | 16441 | 1675 |
KLK6,F12,CTSV,CAPN1 |
| 3.622e-02 | -3.32 | MARVEL | pfam domains | PF01284 | 25 | 6 | 16629 | 1696 |
SYPL1,MAL2,CMTM6,CMTM4,OCLN,CMTM7 |
| 3.624e-02 | -3.32 | organonitrogen compound metabolic process | biological process | GO:1901564 | 1764 | 202 | 16441 | 1675 |
SLC35D2,ACACB,NMRK1,UGT8,HSPG2,EPAS1,MRPS15,AASS,CRYM,SLC25A13,HEXB,MMADHC,TEX2,VARS2,PSME1,OAT,CACNB4,SDC1,SPTB,CHPF,ABCD4,TYMP,CYP1A1,PSMD1,IMPAD1,PAPSS1,SLC44A1,SERINC2,DLG1,AOX1,AKR1B1,TRAM1,APOBEC3G,ERAP2,TNIP1,CDA,NFE2L1,MTRF1L,ICMT,IDH1,MRPS36,TP53I3,POR,HS6ST1,ENPP1,NEIL1,HPSE,P4HA2,DHTKD1,EIF4EBP2,MRPS28,GLA,PCSK5,MRPL44,ALDH6A1,ABCG2,ASAH1,NDUFA4,SLC1A3,B4GALT4,B4GALNT1,GNS,ATP5H,RPL39,PCYOX1,AHCY,PIM1,GAD1,ALDH3A2,MCCC2,ABCC1,CHSY3,GFPT1,PMPCB,B3GNT7,PRODH,MRPS33,ERO1A,PDE5A,EIF2AK1,SPTLC2,PSMA4,AMDHD1,GLCE,FECH,GNAS,NUDT16,SLCO4A1,SLC6A6,PRKAG2,PLPP3,DCK,PRPS2,MDH1,NR4A2,CTSA,XDH,EGLN1,PLA2G4A,PAPSS2,NQO1,IL15,PSME2,XYLT1,SLC7A2,MGST2,LPIN3,CDS1,XYLT2,SRR,RPN2,GOT1,ECE1,PDE4D,EGLN3,DLG3,SULT2B1,NAGA,GM2A,CHP1,CTH,CPD,ENPP4,SEC61B,AKT1,FIGNL1,PANK1,SAT1,SLC11A2,GLO1,ATP1B1,TAPBP,DUOX1,ALDH3B1,ALDH5A1,IDE,DDOST,ABHD12,PNPLA6,SLC27A1,HS3ST3B1,ST3GAL1,LTA4H,NDST3,GCLM,ENO2,CPEB4,HAL,BLVRB,SDC4,PSMD10,CTSZ,APOBEC3H,DSE,SPR,GSTP1,SGPL1,ITGB8,ARSG,A4GALT,GALNS,RRBP1,BAX,SLC44A2,ALDH7A1,CRTAP,FAH,HMMR,B3GALT6,OPLAH,PGM1,B3GNT2,SHMT1,PLSCR1,PSMB4,GUSB,MPP1,GCLC,EIF5A2,FURIN,OGDHL,NADK2,AK4,GGH,BLVRA,ARSK,RNPEP,CPTP,GPLD1,PRDX4,FUCA1,RPL12,ACADSB,DBI,ERAP1,SPCS3,CMPK2,ARSB,SLC25A38,CPEB2,ACOT7,OCLN |
| 3.626e-02 | -3.32 | immune effector process | biological process | GO:0002252 | 459 | 59 | 16441 | 1675 |
DDX58,ANXA3,INPP5D,DNAJC3,TP53,HERC5,APOBEC3H,ITPR2,NCKAP1,EMP2,IL18R1,APOBEC3B,FAM111A,CTSC,ELMO2,GATA2,PLCG2,PIK3CA,DLG1,IFIT1,PIK3CD,OAS3,ULBP2,SYK,S100A13,APOBEC3G,RASGRP1,MX1,CD55,PLSCR1,APOBEC3D,IFITM3,ITCH,MICB,PIK3R1,RC3H2,PTGER4,RGCC,CR2,BTN3A2,YES1,ITPR3,IFIT3,CD40,RNF19B,FAS,PLCG1,SWAP70,LIMK1,RAET1L,ITPR1,NR4A3,NOD2,NLRC5,IRF7,ARPC2,F2RL1,IFIH1,TMEM173 |
| 3.632e-02 | -3.32 | NCAM1 interactions | REACTOME pathways | R-HSA-419037 | 37 | 8 | 8202 | 867 |
COL9A3,COL6A2,ARTN,COL6A1,COL4A5,CACNA1D,NCAM1,CACNB4 |
| 3.632e-02 | -3.32 | ion transport | biological process | GO:0006811 | 1245 | 146 | 16441 | 1675 |
SLC35D2,ACACB,CPT2,TSC22D3,SLC25A13,ATP8A1,CACNA2D2,ITPR2,CACNB4,SLC20A1,SLC8B1,TMC1,SLC9A7,NCS1,PQLC2,CTGF,STIM1,SLC44A1,STEAP2,SERINC2,KCNS3,TRPC1,TMEM37,ANO4,SLC39A10,ORAI2,KCNIP3,SLC35C1,ENPP1,KCNMB4,KCNK1,ATP7B,SARAF,PIEZO1,PRKAA2,LASP1,SCN5A,NFKBIE,FXYD3,SLC22A31,SLC25A27,NDUFA4,SLC36A4,SLC1A3,COX6C,TTYH3,ANO1,CA2,ATP5H,SLC16A6,KCNN4,PCYOX1,FXYD5,SELK,PANX2,CACNA1D,SLC12A2,KCNJ12,SLC37A1,MFI2,ANO6,ERO1A,NPC2,ATP8B3,PCTP,SFXN5,STEAP1,CYB5A,SLCO4A1,CACHD1,GABRD,SLC6A6,PRKAG2,SLC4A4,MFSD2A,TMEM30A,ITPR1,SLC2A6,SH3BP4,SLC4A3,PITPNA,ATP1B3,SHROOM2,NIPA1,MFSD3,PLA2G4A,SLC25A24,SLC2A4,CCDC109B,ATP2C2,FTH1,SLC7A2,ATP6V0B,SCNN1A,FABP6,PLCG2,CNNM4,CDKN1B,ACSL4,SCN2A,F2R,SCN3A,CHP1,CLCN3,OSTM1,SLC39A8,SLC11A2,ATP1B1,ITPR3,ATP10D,ATP13A2,ATP1A1,SLC9A6,SLC27A1,ABCA1,DENND5B,ATP9A,GABRG2,ANO9,SLC9A2,TMEM63A,SLC27A6,BAX,SGK3,SGK1,SLC44A2,ATP8B1,WWP1,ABCD1,SYK,TPCN1,SLC16A5,S100A6,ATP2B1,NCOA2,MRS2,GRIN1,PPARA,CPTP,TMC5,GRIN2D,MCUR1,ITGAV,NDFIP1,ARHGEF9,ABCG1 |
| 3.634e-02 | -3.31 | neuron projection membrane | cellular component | GO:0032589 | 39 | 8 | 17570 | 1756 |
SGCE,ADORA1,GRIN1,GABRG2,NRG1,CNTNAP2,GPER1,GABARAPL1 |
| 3.635e-02 | -3.31 | FA | pfam domains | PF08736 | 13 | 4 | 16629 | 1696 |
EPB41L5,EPB41L4B,EPB41L4A,FARP2 |
| 3.635e-02 | -3.31 | Peptidase_M1 | pfam domains | PF01433 | 13 | 4 | 16629 | 1696 |
ERAP1,RNPEP,LTA4H,ERAP2 |
| 3.635e-02 | -3.31 | OTU | pfam domains | PF02338 | 13 | 4 | 16629 | 1696 |
YOD1,OTUD1,ZRANB1,ALG13 |
| 3.645e-02 | -3.31 | V$FOXO3_01 | MSigDB lists | V$FOXO3_01 | 233 | 32 | 17758 | 1761 |
BIN1,CDKN1C,CHCHD7,ETV5,TEX2,PHLPP1,SEPP1,SH2D4A,VPS26A,TFAP4,FOXP2,ITGA3,FRY,DIXDC1,CITED2,CLIP2,DOCK4,TRIM8,KIF20A,NUB1,RGAG1,FBXO9,LDB2,NFIB,NFIX,PITX2,KLF12,PELI2,NRG1,SEMA3A,MAFF,NR3C2 |
| 3.649e-02 | -3.31 | PXN (paxillin) | protein interactions | 5829 | 107 | 18 | 16036 | 1726 |
CASP3,SORBS1,REPS2,NF2,IQGAP1,ITGA6,SDC4,HDAC6,BCAR1,RASA1,IGF1R,PTEN,LIMK1,TUBG1,AHCY,ITGAV,CTTN,SYK |
| 3.652e-02 | -3.31 | AURKA (aurora kinase A) | protein interactions | 6790 | 223 | 33 | 16036 | 1726 |
TNRC6C,DLGAP5,CNOT8,DCAF7,PTTG1,NDC80,TP53,FTH1,NUF2,HDAC6,PRKACA,BARD1,SNX18,OSBPL3,PASK,TFAP2A,SORL1,TUBG1,PLK1,HMMR,TACC1,CDC20,AMER1,EZR,BORA,RASA1,NIN,RPL12,NFKBIA,TCEAL4,AURKA,WDR62,ARPC2 |
| 3.652e-02 | -3.31 | p38 MAPK Signaling Pathway | WikiPathways | WP400 | 34 | 8 | 4455 | 516 |
MAPKAPK2,PLA2G4A,RASGRF1,MAP3K9,TGFBR1,ELK1,MAP3K5,HSPB1 |
| 3.652e-02 | -3.31 | Endothelin | WikiPathways | WP2197 | 34 | 8 | 4455 | 516 |
GNAS,CALM2,GUCY1B2,GNB5,CALM1,CALM3,ECE1,EDNRA |
| 3.652e-02 | -3.31 | GCTNWTTGK_UNKNOWN | MSigDB lists | GCTNWTTGK_UNKNOWN | 285 | 38 | 17758 | 1761 |
CCNE2,LASP1,CDK17,NKX3-1,TSC22D3,SOX9,ETV5,KIF23,ERBB2,MPP5,NUCB2,SLC20A1,ZNF385B,SESN3,CDH1,ITGB8,SHC3,ANKS1B,CALD1,IL6ST,LMO4,ATRNL1,CDH3,OSTF1,ANO4,CITED2,ETV4,SPRY2,CCDC88A,TRAK2,LAMP2,STRADB,H2AFV,TP53INP2,NFIB,DPYSL3,PRDM5,ESPL1 |
| 3.653e-02 | -3.31 | Vascular smooth muscle contraction | KEGG pathways | ko04270 | 120 | 20 | 6908 | 758 |
MYL9,PLA2G4A,RHOA,ARHGEF11,CALM1,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,ITPR1,PRKG1,CACNA1D,PLCB2 |
| 3.653e-02 | -3.31 | Vascular smooth muscle contraction | KEGG pathways | hsa04270 | 120 | 20 | 6908 | 758 |
MYL9,PLA2G4A,RHOA,ARHGEF11,CALM1,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,ITPR1,PRKG1,CACNA1D,PLCB2 |
| 3.658e-02 | -3.31 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | 182 | 26 | 17758 | 1761 |
GAS2L1,GCA,GAA,EPAS1,PTTG1,OSGIN2,C5orf30,MTRF1L,PDE5A,LRRC1,GRK6,FANCE,ARHGAP35,FUCA1,DNAJC10,MUC16,CTGF,AGPAT2,ACADSB,PAIP2B,RGS3,CLDN4,RPN2,BUB1,ALDH7A1,SLC25A30 |
| 3.658e-02 | -3.31 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | 182 | 26 | 17758 | 1761 |
TGIF1,TRIP10,NR3C1,AASS,CPT2,ATP8A1,CD82,PARP4,BTN3A1,SLC11A2,DHRS3,CYP39A1,GLCE,SCML1,DAPK2,HLF,RBM47,CSF1,PRICKLE3,BCL6,DRAM1,NR4A2,CD70,RFX5,MYLIP,TIAM1 |
| 3.658e-02 | -3.31 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP | 182 | 26 | 17758 | 1761 |
TGIF1,PDGFC,HES1,MBP,PARP12,IFITM3,HLA-E,TAP1,CACNA2D2,NPC2,LTBP3,BCAP31,HLA-A,SCML1,RASGRP2,IER3,BANK1,RBM47,ZFP36,IL6ST,NFKBIA,OPN3,IGFBP2,HLA-C,IFI6,NCOA2 |
| 3.659e-02 | -3.31 | KEGG_CELL_CYCLE | MSigDB lists | KEGG_CELL_CYCLE | 124 | 19 | 17758 | 1761 |
CCNE2,PLK1,CDKN1C,CDC20,PTTG1,TP53,PKMYT1,CCNB1,CDK1,CDKN2C,CCND1,WEE1,RBL1,CDKN1B,HDAC1,BUB1,CCNB2,CDKN2D,ESPL1 |
| 3.659e-02 | -3.31 | SMTTTTGT_UNKNOWN | MSigDB lists | SMTTTTGT_UNKNOWN | 382 | 49 | 17758 | 1761 |
LTBP1,NF2,CPEB4,ARL4C,DHRS3,PDGFB,H1FX,SCML1,FOXP2,SS18,ITGB8,GATA2,ANKS1B,PRICKLE3,CALD1,FLRT3,FRAS1,LMO4,LHX6,ELF5,BCL6,PDE4D,CITED2,TIAM1,DPYSL5,TGIF1,TRIM8,TCF7,ROR1,DUSP4,NIN,NFIX,XKRX,CXXC4,MAPKAPK2,ONECUT1,KLF12,ETS2,PELI2,AMMECR1,ITPR1,NR4A3,NRG1,NR4A2,FZD5,ARPC2,KLF7,JARID2,EHD1 |
| 3.659e-02 | -3.31 | TPR_repeat | interpro domains | IPR019734 | 124 | 19 | 18293 | 1814 |
TTC8,TMTC1,LONRF3,CEP70,TTC39B,DNAJC3,TTC7A,EMC2,GPSM2,IFIT3,NPHP3,AIP,APPBP2,TTC21B,P4HA2,KLC3,CABIN1,IFIT1,TANC2 |
| 3.662e-02 | -3.31 | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3677 | 393 | 17775 | 1757 |
LAMP1,ACACB,GAA,ADD1,HSPG2,VANGL1,SLC25A13,NRG2,OAT,BARD1,GRM5,CDKN2C,PQLC2,AP1M2,ANKS6,ZFP36,IQCE,IL31RA,PIK3CA,FUT1,IRF2,IQCD,TIAM1,MGAT5,XKR8,SPEF2,FBXL16,TNIP1,SNTB2,HSPA12A,TNS1,LOXL2,SAV1,POR,COL12A1,ABR,AHRR,PLCG1,RBM47,DNM1L,PLK2,LIMK1,DHTKD1,RELL1,UNC5B,TRAF5,FGD1,DDX58,SCN5A,MRC2,CDK17,FRMD4A,NFKBIE,FAM169A,GGA1,TBC1D1,MTL5,SLC25A27,ISYNA1,SLC1A3,S100A2,TSPAN7,KIAA1161,RAVER2,RABGGTA,GNS,RALGPS2,FRY,FAM189A1,SNX18,MEGF8,AIM1,DAPK1,TMEM51,PRKG1,OPN3,SORL1,CADPS2,CACNA1D,ZMYM1,RIMS2,IGSF3,GFPT1,FADS2,KCNJ12,KLK5,KIF20A,TBC1D8B,SALL4,ANO6,ATP8B3,NPHP3,ANTXR1,PTPRF,CACHD1,SLC4A4,MATN2,CLMN,PCDH19,CABIN1,DRP2,MAP3K5,XDH,PLA2G4A,FRMPD3,PAPSS2,TRIP10,ST14,CAST,RALBP1,ATP2C2,FTH1,MGST2,APC2,CYP39A1,TNFSF9,MUC16,TRANK1,SH3BP1,DAB2IP,RTKN2,PDE4D,ARL4D,MYT1,SCN3A,MYO5B,DOCK4,CAMSAP3,COL6A2,SEPT6,SYNE2,UTRN,CDCA2,NUSAP1,PRKCQ,ATP10D,AMZ2,JAK1,SHROOM3,CDK19,WFS1,CORO1C,INPP4B,FAM195A,NRG1,NR3C2,COBL,DENND5B,IGFBP6,ATP9A,CENPI,DNAH3,SRPX2,SIX4,PDIA4,CXCL16,TMEM87B,ITGB8,IGSF9,SLC27A6,ANKS1B,PTEN,CALD1,FAM102A,ADAM15,CCDC82,TPCN1,ACBD5,AMOTL2,PDGFC,B3GNT2,RAPGEF2,PIK3R1,GRIN1,UBE2A,DIAPH2,BLVRA,SNTB1,GALNT3,FGFR2,SYT7,ABCB1,CSTF2,GRIN2D,CENPE,ETAA1,FHL1,ESPL1,DCBLD1,TLL2,TMEM131,CCNI,EXPH5,LTBP1,UGT8,EPHA4,FHDC1,NDC80,SDC1,DNER,TMC1,SPTB,PLS3,ZFYVE16,ARHGEF10L,SIPA1L2,LRRC6,MKRN3,ELF5,MITF,ANKFN1,DLG1,ABCA2,POF1B,ANKRD12,NTN4,CTTN,MYH14,TLN2,MYRIP,BTBD3,MYBL1,RASGRP1,ZNF462,PLK1,NLRP4,THRB,MCTP1,CELSR2,CR2,EZR,ROR1,ANLN,IDH1,ZBTB7B,ADRBK2,DZIP1L,ZNF114,GPRC5B,MAP2,RAB11FIP1,ARRDC1,PIK3C2B,EPB41L4A,CAPN1,PCSK5,NR2C2,ARAP3,BMF,PARP12,LRRFIP2,UBASH3B,CNTNAP2,PHLPP1,ADAMTSL4,FBLN1,ANO1,OTUD1,TNS3,IGF1R,GATA2,FRAS1,KIF13B,COL6A1,LIMCH1,PIM1,SLC12A2,GAD1,ALS2CL,MDFI,SNX7,ABCC1,PODXL2,PCDH1,PCBP3,MGAT4B,EIF2AK1,RNF113A,HEATR5A,RANBP9,MFSD7,MUM1L1,CDK5R1,XKRX,PHLPP2,P4HA3,NLRC5,SH3BP4,ZDHHC7,LTBP2,PLD1,ZDBF2,JAK3,SEMA3A,COL16A1,AFAP1,NCKAP5,SPC25,FAM92A1,FOXM1,XYLT1,TP53,CCDC68,ERBB2,MRAS,SLC7A2,LPIN3,PHLDA1,SYTL2,TTC21B,EFR3A,FRYL,FABP6,BCL6,CDH3,NOTCH3,ECE1,SCN2A,CTH,MAP3K3,TMTC1,MBP,AKT1,PTPRU,ERBB2IP,DUSP4,DOCK5,FANCE,CASP4,ATP13A2,ATP1A1,ALDH5A1,ABHD12,PTK7,TLE1,EFNA5,SPTBN5,LIFR,MAN2B2,FBLIM1,COL9A3,SORT1,CDH22,CPEB4,ARHGEF11,KLHL13,RUSC2,POC1B,GABRG2,COL4A5,DSE,LBR,SLC9A2,PPP2R3A,HDAC9,ADRBK1,TOX2,RRBP1,GTF2F2,ARVCF,ABCD1,IGDCC4,DLGAP1,PHF20L1,FBLN5,GUSB,AMFR,NR4A1,ASPM,RC3H2,OGDHL,LRRC66,TTC7A,PRICKLE1,COL7A1,RUNX3,BBS2,KLHL2,SWAP70,FAT4,RND3,NAT1,RAP2C,FAM117A,ARRB1,PPP2R3C,SH3BGRL2,GRAMD1C,SOX8,HIPK3,RAB3IL1,SNPH,GOLGB1 |
| 3.662e-02 | -3.31 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3677 | 393 | 17775 | 1757 |
LAMP1,ACACB,GAA,ADD1,HSPG2,VANGL1,SLC25A13,NRG2,OAT,BARD1,GRM5,CDKN2C,PQLC2,AP1M2,ANKS6,ZFP36,IQCE,IL31RA,PIK3CA,FUT1,IRF2,IQCD,TIAM1,MGAT5,XKR8,SPEF2,FBXL16,TNIP1,SNTB2,HSPA12A,TNS1,LOXL2,SAV1,POR,COL12A1,ABR,AHRR,PLCG1,RBM47,DNM1L,PLK2,LIMK1,DHTKD1,RELL1,UNC5B,TRAF5,FGD1,DDX58,SCN5A,MRC2,CDK17,FRMD4A,NFKBIE,FAM169A,GGA1,TBC1D1,MTL5,SLC25A27,ISYNA1,SLC1A3,S100A2,TSPAN7,KIAA1161,RAVER2,RABGGTA,GNS,RALGPS2,FRY,FAM189A1,SNX18,MEGF8,AIM1,DAPK1,TMEM51,PRKG1,OPN3,SORL1,CADPS2,CACNA1D,ZMYM1,RIMS2,IGSF3,GFPT1,FADS2,KCNJ12,KLK5,KIF20A,TBC1D8B,SALL4,ANO6,ATP8B3,NPHP3,ANTXR1,PTPRF,CACHD1,SLC4A4,MATN2,CLMN,PCDH19,CABIN1,DRP2,MAP3K5,XDH,PLA2G4A,FRMPD3,PAPSS2,TRIP10,ST14,CAST,RALBP1,ATP2C2,FTH1,MGST2,APC2,CYP39A1,TNFSF9,MUC16,TRANK1,SH3BP1,DAB2IP,RTKN2,PDE4D,ARL4D,MYT1,SCN3A,MYO5B,DOCK4,CAMSAP3,COL6A2,SEPT6,SYNE2,UTRN,CDCA2,NUSAP1,PRKCQ,ATP10D,AMZ2,JAK1,SHROOM3,CDK19,WFS1,CORO1C,INPP4B,FAM195A,NRG1,NR3C2,COBL,DENND5B,IGFBP6,ATP9A,CENPI,DNAH3,SRPX2,SIX4,PDIA4,CXCL16,TMEM87B,ITGB8,IGSF9,SLC27A6,ANKS1B,PTEN,CALD1,FAM102A,ADAM15,CCDC82,TPCN1,ACBD5,AMOTL2,PDGFC,B3GNT2,RAPGEF2,PIK3R1,GRIN1,UBE2A,DIAPH2,BLVRA,SNTB1,GALNT3,FGFR2,SYT7,ABCB1,CSTF2,GRIN2D,CENPE,ETAA1,FHL1,ESPL1,DCBLD1,TLL2,TMEM131,CCNI,EXPH5,LTBP1,UGT8,EPHA4,FHDC1,NDC80,SDC1,DNER,TMC1,SPTB,PLS3,ZFYVE16,ARHGEF10L,SIPA1L2,LRRC6,MKRN3,ELF5,MITF,ANKFN1,DLG1,ABCA2,POF1B,ANKRD12,NTN4,CTTN,MYH14,TLN2,MYRIP,BTBD3,MYBL1,RASGRP1,ZNF462,PLK1,NLRP4,THRB,MCTP1,CELSR2,CR2,EZR,ROR1,ANLN,IDH1,ZBTB7B,ADRBK2,DZIP1L,ZNF114,GPRC5B,MAP2,RAB11FIP1,ARRDC1,PIK3C2B,EPB41L4A,CAPN1,PCSK5,NR2C2,ARAP3,BMF,PARP12,LRRFIP2,UBASH3B,CNTNAP2,PHLPP1,ADAMTSL4,FBLN1,ANO1,OTUD1,TNS3,IGF1R,GATA2,FRAS1,KIF13B,COL6A1,LIMCH1,PIM1,SLC12A2,GAD1,ALS2CL,MDFI,SNX7,ABCC1,PODXL2,PCDH1,PCBP3,MGAT4B,EIF2AK1,RNF113A,HEATR5A,RANBP9,MFSD7,MUM1L1,CDK5R1,XKRX,PHLPP2,P4HA3,NLRC5,SH3BP4,ZDHHC7,LTBP2,PLD1,ZDBF2,JAK3,SEMA3A,COL16A1,AFAP1,NCKAP5,SPC25,FAM92A1,FOXM1,XYLT1,TP53,CCDC68,ERBB2,MRAS,SLC7A2,LPIN3,PHLDA1,SYTL2,TTC21B,EFR3A,FRYL,FABP6,BCL6,CDH3,NOTCH3,ECE1,SCN2A,CTH,MAP3K3,TMTC1,MBP,AKT1,PTPRU,ERBB2IP,DUSP4,DOCK5,FANCE,CASP4,ATP13A2,ATP1A1,ALDH5A1,ABHD12,PTK7,TLE1,EFNA5,SPTBN5,LIFR,MAN2B2,FBLIM1,COL9A3,SORT1,CDH22,CPEB4,ARHGEF11,KLHL13,RUSC2,POC1B,GABRG2,COL4A5,DSE,LBR,SLC9A2,PPP2R3A,HDAC9,ADRBK1,TOX2,RRBP1,GTF2F2,ARVCF,ABCD1,IGDCC4,DLGAP1,PHF20L1,FBLN5,GUSB,AMFR,NR4A1,ASPM,RC3H2,OGDHL,LRRC66,TTC7A,PRICKLE1,COL7A1,RUNX3,BBS2,KLHL2,SWAP70,FAT4,RND3,NAT1,RAP2C,FAM117A,ARRB1,PPP2R3C,SH3BGRL2,GRAMD1C,SOX8,HIPK3,RAB3IL1,SNPH,GOLGB1 |
| 3.664e-02 | -3.31 | DTNA (dystrobrevin, alpha) | protein interactions | 1837 | 30 | 7 | 16036 | 1726 |
SNTA1,SEC23A,KCNJ12,SNTB1,DRP2,SNTB2,UTRN |
| 3.664e-02 | -3.31 | IL2RB (interleukin 2 receptor, beta) | protein interactions | 3560 | 30 | 7 | 16036 | 1726 |
JAK1,IL15RA,IL15,JAK3,SYK,PIK3R1,SOCS3 |
| 3.664e-02 | -3.31 | LYPD6 (LY6/PLAUR domain containing 6) | protein interactions | 130574 | 30 | 7 | 16036 | 1726 |
TMEM68,MINPP1,TCTN2,CELSR2,LPGAT1,TMEM245,CKAP4 |
| 3.669e-02 | -3.31 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | 92 | 15 | 17758 | 1761 |
PSMD1,PSMB4,NFKBIE,AKT1,PTEN,NR4A1,PSME2,NFKBIA,CASP9,CDKN1B,PSMD10,PSME1,PHLPP1,PSMA4,RASGRP1 |
| 3.669e-02 | -3.31 | REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 92 | 15 | 17758 | 1761 |
MAP3K3,CARD8,RHOA,RIPK2,TSPAN6,PLK2,SECTM1,LITAF,NOD2,SLC44A2,CD40,F2R,TRAF5,NDFIP1,SLC20A1 |
| 3.669e-02 | -3.31 | LU_IL4_SIGNALING | MSigDB lists | LU_IL4_SIGNALING | 92 | 15 | 17758 | 1761 |
GNAS,NCOA3,SMARCA2,PHF20L1,ARAP2,CTGF,MRPS15,STAT4,SPINT2,BCL6,SELL,NFKBIZ,MAP3K5,CMTM6,RRAGD |
| 3.669e-02 | -3.31 | positive regulation of protein kinase B signaling | biological process | GO:0051897 | 82 | 14 | 16441 | 1675 |
PDGFA,TXN,PINK1,PTPRJ,HPSE,IGF1R,AXL,ARFGEF1,FAM110C,TGFBR1,NRG1,MYDGF,SPRY2,KIAA1161 |
| 3.672e-02 | -3.30 | regulation of phagocytosis | biological process | GO:0050764 | 67 | 12 | 16441 | 1675 |
GATA2,PTEN,ANO6,NOD2,ITGAV,PLD1,CAMK1D,F2RL1,MERTK,RAP1GAP,SYK,ABR |
| 3.672e-02 | -3.30 | neural nucleus development | biological process | GO:0048857 | 67 | 12 | 16441 | 1675 |
CALM2,FOXP2,MBP,RHOA,ALDH1A3,CALM1,NDRG2,CALM3,SCRIB,HOXB2,NFIB,CDK5R1 |
| 3.672e-02 | -3.30 | regulation of Notch signaling pathway | biological process | GO:0008593 | 67 | 12 | 16441 | 1675 |
HES1,NOV,LLGL2,TSPAN15,GATA2,IL6ST,BMP7,NFKBIA,BCL6,NOD2,SLC35C1,EGFL7 |
| 3.677e-02 | -3.30 | small molecule catabolic process | biological process | GO:0044282 | 329 | 44 | 16441 | 1675 |
ENO2,ALDH6A1,AASS,CRYM,CPT2,HAL,LPIN3,OAT,CYP39A1,CYP26A1,CYP1A1,FUT2,CYP4F11,PTEN,FUT8,BDH1,PCYOX1,FUT1,ECI2,ALDH7A1,GOT1,AHCY,ABCD1,ACOX2,GAD1,MCCC2,FAH,CTH,CYP26B1,PRODH,PGM1,SHMT1,ALDH2,CYP4F3,AMDHD1,NUDT16,ALDH3B1,ALDH5A1,ACADSB,FAAH,ABHD12,PEX2,PGM2L1,ACOT7 |
| 3.677e-02 | -3.30 | RET (ret proto-oncogene) | protein interactions | 5979 | 43 | 9 | 16036 | 1726 |
PTPRF,PLCG1,SHC3,DOK4,RET,PIK3R1,NOTCH3,AIP,GAB1 |
| 3.677e-02 | -3.30 | NME1-NME2 (NME1-NME2 readthrough) | protein interactions | 654364 | 43 | 9 | 16036 | 1726 |
PPIF,ENO2,AKR1B1,AHCY,GOT1,TAGLN2,OAT,IDH1,SNX12 |
| 3.680e-02 | -3.30 | RHO GTPase Effectors | REACTOME pathways | R-HSA-195258 | 285 | 40 | 8202 | 867 |
MYL9,WASF3,SPC25,NF2,CIT,CENPI,IQGAP1,NDC80,CDCA8,CALM3,NUF2,NCKAP1,PKN1,CENPN,CALM2,KIF5B,CDH1,KIF14,KLC3,CDKN1B,BUB1,CTTN,MYH14,IQGAP3,NUP85,NCOA2,DVL2,PLK1,RHOA,CENPA,ZWINT,CDC20,CALM1,DIAPH2,PPP2R5A,LIMK1,CENPE,NDE1,ARPC2,MYL12B |
| 3.683e-02 | -3.30 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | 157 | 23 | 17758 | 1761 |
SIRT1,MX1,TGIF1,NR4A1,CAMKK1,PTGER4,IFIT3,TP53INP2,MAPK8IP1,GPLD1,SCML1,IRS2,NR4A3,RAB11FIP1,ZNF165,SUN3,IRF7,NR4A2,HOXB13,IFIT1,GEM,DDX59,NIPA1 |
| 3.686e-02 | -3.30 | DAZARD_RESPONSE_TO_UV_SCC_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_UP | 116 | 18 | 17758 | 1761 |
LAMP2,ANXA3,NF2,CDKN1C,PLSCR1,SH3BGRL,TSC22D3,IL13RA1,ARHGDIB,FOS,CDK1,CYB5A,SCARB2,TACSTD2,ALDH7A1,CITED2,PDIA6,TOB1 |
| 3.692e-02 | -3.30 | right_middle_lobe | COSMIC cancer mutations | right_middle_lobe | 8 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 3.692e-02 | -3.30 | skin-acral-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-acral-malignant_melanoma-acral_lentiginous | 8 | 3 | 17775 | 1757 |
PTEN,GNA11,PIK3CA |
| 3.692e-02 | -3.30 | choroid_plexus_papilloma | COSMIC cancer mutations | choroid_plexus_papilloma | 8 | 3 | 17775 | 1757 |
NF2,IDH1,TP53 |
| 3.692e-02 | -3.30 | penis-carcinoma | COSMIC cancer mutations | penis-carcinoma | 8 | 3 | 17775 | 1757 |
PTEN,PIK3CA,TP53 |
| 3.692e-02 | -3.30 | endometrium-hyperplasia | COSMIC cancer mutations | endometrium-hyperplasia | 8 | 3 | 17775 | 1757 |
PTEN,PIK3CA,TP53 |
| 3.692e-02 | -3.30 | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | COSMIC cancer mutations | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | 8 | 3 | 17775 | 1757 |
NF2,IDH1,TP53 |
| 3.692e-02 | -3.30 | lung-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | lung-other-dysplasia-carcinoma_in_situ | 8 | 3 | 17775 | 1757 |
ERBB2,PIK3CA,TP53 |
| 3.692e-02 | -3.30 | large_intestine-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-serrated_polyp-serrated_adenoma | 8 | 3 | 17775 | 1757 |
GNAS,PIK3CA,TP53 |
| 3.695e-02 | -3.30 | Prot-tyrosine_phosphatase-like | interpro domains | IPR029021 | 100 | 16 | 18293 | 1814 |
SSH3,MTM1,SSH1,PTPRU,PTPN9,TNS1,SBF1,DUSP4,PTPRF,TNS3,PTPRJ,PTEN,PALD1,DUSP10,MTMR11,PTPRE |
| 3.697e-02 | -3.30 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | 260 | 35 | 17775 | 1757 |
EXPH5,GLIS3,ILDR1,ARHGEF11,RET,TP53,ERBB2,PLXNA1,SBF1,NEO1,CDKN2C,MUC16,PTEN,OSBPL3,AIM1,PCYOX1,PIK3CA,CACNA1D,PANX2,PHKA2,MYT1,NEB,RIMS2,FARP2,AKT1,PIK3R1,HEATR5A,IDH1,GNA11,MAP3K6,GNAS,SHROOM3,SLC9A6,UNC5B,TANC2 |
| 3.699e-02 | -3.30 | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | MSigDB lists | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | 108 | 17 | 17758 | 1761 |
PLA2G4A,ELK3,RUNX2,IL15RA,SEPT6,FURIN,PDGFB,TSPAN7,BFSP1,CTGF,MAP2,CYR61,BMP1,SGK1,FXYD5,CD70,AHR |
| 3.699e-02 | -3.30 | positive regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050731 | 153 | 23 | 16441 | 1675 |
HES1,RIPK2,IL15,TP53,IL18,TEC,YES1,CD40,PDGFB,GPRC5B,ADORA1,SEMA4D,IL6ST,PLPP3,IL31RA,NOD2,NRG1,EFNA5,ERBB3,LRRK1,WNT3A,SYK,DVL2 |
| 3.707e-02 | -3.30 | adrenergic receptor binding | molecular function | GO:0031690 | 19 | 5 | 16491 | 1673 |
GNAS,ARRB1,PDE4D,ADRBK1,RAPGEF2 |
| 3.707e-02 | -3.30 | 14-3-3 protein binding | molecular function | GO:0071889 | 19 | 5 | 16491 | 1673 |
IRS2,DAB2IP,AKT1,ZFP36,KIF13B |
| 3.723e-02 | -3.29 | Tensin_lipid_phosphatase_dom | interpro domains | IPR029023 | 8 | 3 | 18293 | 1814 |
TNS1,TNS3,PTEN |
| 3.723e-02 | -3.29 | PI3K_C2_dom | interpro domains | IPR002420 | 8 | 3 | 18293 | 1814 |
PIK3C2B,PIK3CD,PIK3CA |
| 3.723e-02 | -3.29 | Tensin_C2-dom | interpro domains | IPR014020 | 8 | 3 | 18293 | 1814 |
TNS1,TNS3,PTEN |
| 3.723e-02 | -3.29 | CLIMENT_BREAST_CANCER_COPY_NUMBER_DN | MSigDB lists | CLIMENT_BREAST_CANCER_COPY_NUMBER_DN | 8 | 3 | 17758 | 1761 |
NRG1,KIF13B,CASP9 |
| 3.723e-02 | -3.29 | TURJANSKI_MAPK8_AND_MAPK9_TARGETS | MSigDB lists | TURJANSKI_MAPK8_AND_MAPK9_TARGETS | 8 | 3 | 17758 | 1761 |
ELK3,ELK1,TP53 |
| 3.723e-02 | -3.29 | GALI_TP53_TARGETS_APOPTOTIC_UP | MSigDB lists | GALI_TP53_TARGETS_APOPTOTIC_UP | 8 | 3 | 17758 | 1761 |
CD40,CASP4,BAX |
| 3.723e-02 | -3.29 | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | 8 | 3 | 17758 | 1761 |
BCL2L1,PLK2,BLVRB |
| 3.723e-02 | -3.29 | LE_SKI_TARGETS_DN | MSigDB lists | LE_SKI_TARGETS_DN | 8 | 3 | 17758 | 1761 |
COL18A1,TIMP3,FHL1 |
| 3.723e-02 | -3.29 | PEPTIDE_METABOLIC_PROCESS | MSigDB lists | PEPTIDE_METABOLIC_PROCESS | 8 | 3 | 17758 | 1761 |
TAPBP,FURIN,PCSK5 |
| 3.723e-02 | -3.29 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | MSigDB lists | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | 8 | 3 | 17758 | 1761 |
ITPR2,ITPR3,STIM1 |
| 3.723e-02 | -3.29 | ACCGAGC,MIR-423 | MSigDB lists | ACCGAGC,MIR-423 | 8 | 3 | 17758 | 1761 |
DLGAP1,FGFR2,RAP2C |
| 3.723e-02 | -3.29 | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | MSigDB lists | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | 8 | 3 | 17758 | 1761 |
COBL,ETV5,JARID2 |
| 3.723e-02 | -3.29 | MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_DN | MSigDB lists | MILICIC_FAMILIAL_ADENOMATOUS_POLYPOSIS_DN | 8 | 3 | 17758 | 1761 |
MYL9,CR2,FBLN1 |
| 3.723e-02 | -3.29 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | 8 | 3 | 17758 | 1761 |
EGLN3,NR4A1,SGPL1 |
| 3.723e-02 | -3.29 | NAISHIRO_CTNNB1_TARGETS_WITH_LEF1_MOTIF | MSigDB lists | NAISHIRO_CTNNB1_TARGETS_WITH_LEF1_MOTIF | 8 | 3 | 17758 | 1761 |
SGK1,IGFBP2,ITGA6 |
| 3.723e-02 | -3.29 | MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_1 | MSigDB lists | MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_1 | 8 | 3 | 17758 | 1761 |
GRN,FOS,SAT1 |
| 3.723e-02 | -3.29 | NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON | 8 | 3 | 17758 | 1761 |
PPIF,ZMIZ1,ZCCHC24 |
| 3.725e-02 | -3.29 | RAB3B (RAB3B, member RAS oncogene family) | protein interactions | 5865 | 18 | 5 | 16036 | 1726 |
CALM3,TGFBR1,TGOLN2,RIMS2,CALM1 |
| 3.725e-02 | -3.29 | AMY1C (amylase, alpha 1C (salivary)) | protein interactions | 278 | 18 | 5 | 16036 | 1726 |
B3GALNT1,PMPCB,PRKAR2B,CAMK1D,ACTR8 |
| 3.725e-02 | -3.29 | SFRP4 (secreted frizzled-related protein 4) | protein interactions | 6424 | 18 | 5 | 16036 | 1726 |
SIRT1,RASSF8,FBLN1,PASK,PPP2R3A |
| 3.725e-02 | -3.29 | PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta) | protein interactions | 5293 | 18 | 5 | 16036 | 1726 |
IRS2,FAM195A,PIK3CD,TNIP1,PIK3R1 |
| 3.725e-02 | -3.29 | SH3BP1 (SH3-domain binding protein 1) | protein interactions | 23616 | 18 | 5 | 16036 | 1726 |
NLRP4,RHOA,SH3BP1,TRIP10,TIPRL |
| 3.725e-02 | -3.29 | ARSA (arylsulfatase A) | protein interactions | 410 | 18 | 5 | 16036 | 1726 |
CTSL,PLAUR,GALNS,MESDC2,PDIA5 |
| 3.725e-02 | -3.29 | DLGAP4 (discs, large (Drosophila) homolog-associated protein 4) | protein interactions | 22839 | 18 | 5 | 16036 | 1726 |
BIN1,GRIN2D,DLG3,DLG1,GRIN1 |
| 3.731e-02 | -3.29 | N-Glycan biosynthesis | KEGG pathways | ko00510 | 49 | 10 | 6908 | 758 |
MAN2A2,DDOST,MGAT4A,ALG13,DOLPP1,FUT8,MGAT4B,RPN2,MGAT5B,MGAT5 |
| 3.731e-02 | -3.29 | N-Glycan biosynthesis | KEGG pathways | hsa00510 | 49 | 10 | 6908 | 758 |
MAN2A2,DDOST,DOLPP1,MGAT4A,ALG13,MGAT4B,FUT8,RPN2,MGAT5B,MGAT5 |
| 3.736e-02 | -3.29 | - | gene3d domains | 1.10.840.10 | 30 | 7 | 9988 | 1080 |
BCAR3,RASGRF1,RALGPS2,RASGEF1A,RAPGEF2,RASGRP1,RASGRP2 |
| 3.744e-02 | -3.29 | Response to statin therapy(PMID:20339536) | GWAS genes | Response to statin therapy(PMID:20339536) | 12 | 4 | 2389 | 269 |
CLMN,TTC7A,FADS2,CELSR2 |
| 3.750e-02 | -3.28 | divalent inorganic cation transmembrane transporter activity | molecular function | GO:0072509 | 162 | 24 | 16491 | 1673 |
ORAI2,CCDC109B,ATP2C2,MRS2,GRIN1,CACNA2D2,SLC11A2,ITPR2,ITPR3,CACNB4,SLC8B1,TMC1,NCS1,ITPR1,TRPC1,CNNM4,ITGAV,CACNA1D,TMEM37,SLC39A10,TPCN1,NIPA1,ATP2B1,DENND5B |
| 3.754e-02 | -3.28 | NEGATIVE_REGULATION_OF_APOPTOSIS | MSigDB lists | NEGATIVE_REGULATION_OF_APOPTOSIS | 149 | 22 | 17758 | 1761 |
CASP3,GCLC,HTATIP2,GLO1,BCL2L1,GSTP1,BARD1,CDK1,RASA1,FAS,SOCS3,IER3,IGF1R,SCG2,SEMA4D,BAX,HDAC1,PIM1,HSPB1,CDKN2D,IFI6,HIPK3 |
| 3.754e-02 | -3.28 | BIDUS_METASTASIS_DN | MSigDB lists | BIDUS_METASTASIS_DN | 149 | 22 | 17758 | 1761 |
BIN1,NUDT6,ACACB,PHF20L1,FRMD4A,TBC1D8B,RASSF7,ISOC2,STK17B,SIRPA,PARM1,GABARAPL1,KLHL2,METTL7A,GATA2,TMC5,DRAM1,MARCH2,SYK,AHR,CPPED1,EHD1 |
| 3.757e-02 | -3.28 | HCK (HCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3055 | 78 | 14 | 16036 | 1726 |
IRF2BPL,PLCG1,SH3BP1,PLAUR,IL6ST,INPP5D,PLCG2,PIK3R1,ADAM15,ARRB1,ERBB3,BCAR1,RASA1,SH3KBP1 |
| 3.759e-02 | -3.28 | PID_AP1_PATHWAY | MSigDB lists | PID_AP1_PATHWAY | 69 | 12 | 17758 | 1761 |
CCND1,PTEN,CYR61,NR3C1,GATA2,FOSB,TP53,CDKN1B,FOS,ETS1,CDK1,HLA-A |
| 3.764e-02 | -3.28 | KEGG_NON_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_NON_SMALL_CELL_LUNG_CANCER | 54 | 10 | 17758 | 1761 |
CCND1,PLCG1,AKT1,CASP9,PLCG2,PIK3R1,PIK3CA,TP53,ERBB2,PIK3CD |
| 3.764e-02 | -3.28 | HALLMARK_TGF_BETA_SIGNALING | MSigDB lists | HALLMARK_TGF_BETA_SIGNALING | 54 | 10 | 17758 | 1761 |
BCAR3,TGIF1,RHOA,CDH1,CDKN1C,FURIN,HDAC1,TGFBR1,LTBP2,SLC20A1 |
| 3.764e-02 | -3.28 | MORF_GPX4 | MSigDB lists | MORF_GPX4 | 54 | 10 | 17758 | 1761 |
PSMB4,DDOST,DAP,TMBIM6,TECR,BCAP31,MYL12B,RHEB,KDELR1,GPX4 |
| 3.766e-02 | -3.28 | cytoplasmic sequestering of transcription factor | biological process | GO:0042994 | 19 | 5 | 16441 | 1675 |
PSMD10,NFKBIE,THRA,NFKBIA,MDFI |
| 3.766e-02 | -3.28 | positive regulation of chromosome segregation | biological process | GO:0051984 | 19 | 5 | 16441 | 1675 |
PLK1,CCNB1,DLGAP5,PTEN,ESPL1 |
| 3.766e-02 | -3.28 | smooth muscle tissue development | biological process | GO:0048745 | 19 | 5 | 16441 | 1675 |
OSR1,ZFAND5,TIPARP,SOX9,DLG1 |
| 3.766e-02 | -3.28 | labyrinthine layer blood vessel development | biological process | GO:0060716 | 19 | 5 | 16441 | 1675 |
HES1,HS6ST1,FZD5,AKT1,CYR61 |
| 3.766e-02 | -3.28 | positive regulation of natural killer cell activation | biological process | GO:0032816 | 19 | 5 | 16441 | 1675 |
LAMP1,IL18,IL15,AXL,RASGRP1 |
| 3.766e-02 | -3.28 | cellular sodium ion homeostasis | biological process | GO:0006883 | 19 | 5 | 16441 | 1675 |
SGK1,ATP1A1,ATP1B1,ATP1B3,SGK3 |
| 3.766e-02 | -3.28 | cellular response to virus | biological process | GO:0098586 | 19 | 5 | 16441 | 1675 |
DDX58,MAPK11,IRF7,BCL2L1,IFIH1 |
| 3.766e-02 | -3.28 | regulation of calcineurin-NFAT signaling cascade | biological process | GO:0070884 | 19 | 5 | 16441 | 1675 |
NRG1,ERBB3,RCAN3,LMCD1,CHP1 |
| 3.777e-02 | -3.28 | GSE27786_NKTCELL_VS_ERYTHROBLAST_DN | MSigDB lists | GSE27786_NKTCELL_VS_ERYTHROBLAST_DN | 191 | 27 | 17758 | 1761 |
B3GNT7,FBLIM1,CITED4,FAM169A,CDH22,NDC80,SERTAD3,KIF23,EIF2AK1,SPNS3,GNA11,DHX32,EPN3,DNAJC10,DUOX1,BTG3,MDM1,WIPI1,FAM110C,TNFRSF12A,DIXDC1,ACOX2,IQGAP3,WDR62,WBSCR27,TIAM1,NUP85 |
| 3.777e-02 | -3.28 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 191 | 27 | 17758 | 1761 |
KIF20A,USP18,CNOT8,MRS2,RUNX3,GTF3A,ICMT,SDC1,TYSND1,RAD23A,TOP2A,IL6ST,TMEM51,ZDHHC7,NR4A2,TNFRSF12A,MRPS28,IRF7,AHCY,HS3ST3B1,PIEZO1,CENPE,PLOD3,REEP4,SLC27A3,RASGRP1,PARP9 |
| 3.777e-02 | -3.28 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | 191 | 27 | 17758 | 1761 |
FBLIM1,MBP,MRPS33,GOLIM4,CNOT8,PDCL,NDUFA4,ARHGDIB,GGH,DPP8,DHX32,FAM111A,CDK19,RAB11FIP2,CD9,AKR1B1,MDH1,CTSA,GLA,PHKA2,BTBD3,CRTAP,S100A6,RAB3IL1,MCCC2,MELK,NXT2 |
| 3.777e-02 | -3.28 | GSE22886_TH1_VS_TH2_12H_ACT_UP | MSigDB lists | GSE22886_TH1_VS_TH2_12H_ACT_UP | 191 | 27 | 17758 | 1761 |
TGIF1,PAPSS2,SERPINE2,PRSS23,AKT1,PLSCR1,RPS6KA1,XYLT1,CTDSPL,IER3,B3GALNT1,MDM1,AP1M2,MID1IP1,RPL12,ACADSB,PTEN,DPYSL2,FUT8,NR4A3,OTUB2,TWIST1,DIXDC1,GLB1L2,EPB41L4B,TMEM131,MAPK12 |
| 3.777e-02 | -3.28 | ALONSO_METASTASIS_UP | MSigDB lists | ALONSO_METASTASIS_UP | 191 | 27 | 17758 | 1761 |
HMMR,CD63,ANO6,MMADHC,AK4,PDE5A,GGH,GLO1,NPC2,ANLN,SEPP1,LHFPL2,KIF11,TP53I3,WEE1,ATP6V0B,APLP2,IDE,DCK,FAM114A1,SERINC2,MDH1,ITGAV,FHL1,FAIM,HSPB1,WBP5 |
| 3.777e-02 | -3.28 | GSE17721_LPS_VS_POLYIC_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_24H_BMDM_DN | 191 | 27 | 17758 | 1761 |
LAMP2,SIRT1,GCA,ZNF395,IFITM3,FZD4,PSME2,IQGAP1,PTTG1,ARL4C,CBX6,KCTD12,PSME1,FNDC3A,RND3,SLC16A6,DOLPP1,SPINT2,RAP2C,FAM13B,IRF2,ARRB1,PRIMA1,PLCB2,L1CAM,CTDSP2,JARID2 |
| 3.782e-02 | -3.28 | PAS | pfam domains | PF00989 | 19 | 5 | 16629 | 1696 |
AHRR,NCOA3,EPAS1,AHR,NCOA2 |
| 3.782e-02 | -3.28 | FG-GAP | pfam domains | PF01839 | 19 | 5 | 16629 | 1696 |
ITGAV,ITGA3,ITGA7,ITGA6,GPLD1 |
| 3.784e-02 | -3.27 | soft_tissue-fat-liposarcoma | COSMIC cancer mutations | soft_tissue-fat-liposarcoma | 26 | 6 | 17775 | 1757 |
ERBB2,SS18,AKT1,IDH1,PIK3CA,TP53 |
| 3.784e-02 | -3.27 | soft_tissue-nerve_sheath-schwannoma | COSMIC cancer mutations | soft_tissue-nerve_sheath-schwannoma | 26 | 6 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN,RET,PIK3CA |
| 3.784e-02 | -3.27 | glomus_tumour | COSMIC cancer mutations | glomus_tumour | 26 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.784e-02 | -3.27 | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | 26 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.784e-02 | -3.27 | adenosquamous_carcinoma | COSMIC cancer mutations | adenosquamous_carcinoma | 26 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.784e-02 | -3.27 | soft_tissue-blood_vessel-glomus_tumour | COSMIC cancer mutations | soft_tissue-blood_vessel-glomus_tumour | 26 | 6 | 17775 | 1757 |
ERBB2,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.786e-02 | -3.27 | V$STAT4_01 | MSigDB lists | V$STAT4_01 | 251 | 34 | 17758 | 1761 |
RUNX2,CPEB4,FAM81A,ETS1,TNFRSF19,ZNF385B,MECOM,TFAP4,CD109,NPNT,PHTF1,MITF,SGK1,TWIST1,PDE4D,NCAM1,CITED2,TRIM62,DOCK4,PCDH1,NR4A1,PBK,RUNX3,PITX2,CXXC4,PTK7,ABCB1,NRG1,OSR1,ARPC2,NDFIP1,HIPK3,AFAP1,HOXC13 |
| 3.788e-02 | -3.27 | cell-type specific apoptotic process | biological process | GO:0097285 | 90 | 15 | 16441 | 1675 |
CTSL,CASP3,RPS6KA2,AKT1,SIVA1,CASP9,TP53,BAX,DAB2IP,ERBB3,BCL2L1,PKN1,ARF6,SCN2A,FAS |
| 3.788e-02 | -3.27 | regulation of axon extension | biological process | GO:0030516 | 90 | 15 | 16441 | 1675 |
SEMA6B,SEMA4D,DPYSL2,LIMK1,MEGF8,TNFRSF12A,NRG1,CTTN,SEMA3G,PLXNA1,WNT3A,SEMA3A,L1CAM,CDK5R1,SEMA3B |
| 3.788e-02 | -3.27 | vacuolar transport | biological process | GO:0007034 | 90 | 15 | 16441 | 1675 |
LAMP1,ZFYVE16,MTM1,SCARB2,SORT1,GNPTAB,SORL1,SNX16,SPTBN5,KIF13A,ARSB,NDFIP1,HOOK1,HMGXB4,M6PR |
| 3.788e-02 | -3.27 | CD63 (CD63 molecule) | protein interactions | 967 | 24 | 6 | 16036 | 1726 |
LGALS3,PTGFRN,SDC1,CD82,ITGA6,CD9 |
| 3.788e-02 | -3.27 | ETV1 (ets variant 1) | protein interactions | 2115 | 24 | 6 | 16036 | 1726 |
MAPKAPK2,NCOA3,PRKACA,RPS6KA1,NCOA2,TP53 |
| 3.788e-02 | -3.27 | CKS2 (CDC28 protein kinase regulatory subunit 2) | protein interactions | 1164 | 24 | 6 | 16036 | 1726 |
CAMK1D,CCNB1,CCNB2,CDK1,ESPL1,CKS2 |
| 3.788e-02 | -3.27 | ART3 (ADP-ribosyltransferase 3) | protein interactions | 419 | 24 | 6 | 16036 | 1726 |
GALNT7,ALCAM,ARSK,ITGA7,MGAT5,HSPA12A |
| 3.788e-02 | -3.27 | RHOD (ras homolog family member D) | protein interactions | 29984 | 24 | 6 | 16036 | 1726 |
DIAPH2,ADCK5,TGFBR1,PLXNA1,SPTB,PCBP3 |
| 3.788e-02 | -3.27 | AHCYL2 (adenosylhomocysteinase-like 2) | protein interactions | 23382 | 24 | 6 | 16036 | 1726 |
GRN,DHX8,UNKL,PITX2,MSL1,DOK4 |
| 3.788e-02 | -3.27 | INS (insulin) | protein interactions | 3630 | 24 | 6 | 16036 | 1726 |
NOV,SYTL4,IDE,IGF1R,HSPB1,RGS20 |
| 3.788e-02 | -3.27 | MDK (midkine (neurite growth-promoting factor 2)) | protein interactions | 4192 | 24 | 6 | 16036 | 1726 |
MDK,NCAM1,TSPAN1,JAK1,SDC1,SDC4 |
| 3.788e-02 | -3.27 | NQO1 (NAD(P)H dehydrogenase, quinone 1) | protein interactions | 1728 | 24 | 6 | 16036 | 1726 |
GOT1,DAZAP1,ING1,NQO1,FOS,TP53 |
| 3.788e-02 | -3.27 | ERO1A (endoplasmic reticulum oxidoreductase alpha) | protein interactions | 30001 | 24 | 6 | 16036 | 1726 |
PDIA3,FBXO6,PELI2,APPBP2,ERO1A,PDIA4 |
| 3.788e-02 | -3.27 | TXNIP (thioredoxin interacting protein) | protein interactions | 10628 | 24 | 6 | 16036 | 1726 |
HDAC1,CDKN1B,FHL1,TXN,ITCH,TP53 |
| 3.788e-02 | -3.27 | SPC24 (SPC24, NDC80 kinetochore complex component) | protein interactions | 147841 | 24 | 6 | 16036 | 1726 |
BUB1,NUF2,ZWINT,SPC25,ASPM,NDC80 |
| 3.800e-02 | -3.27 | zonula adherens | cellular component | GO:0005915 | 8 | 3 | 17570 | 1756 |
CAMSAP3,SORBS1,PVRL2 |
| 3.800e-02 | -3.27 | apical cortex | cellular component | GO:0045179 | 8 | 3 | 17570 | 1756 |
MYO5B,SPTBN5,GM2A |
| 3.802e-02 | -3.27 | IDH1 (isocitrate dehydrogenase 1 (NADP+)) | protein interactions | 3417 | 50 | 10 | 16036 | 1726 |
RCN1,SLC2A4,DAZAP1,DCK,RANBP1,EFHD2,CAB39,GOT1,LTA4H,ARF4 |
| 3.803e-02 | -3.27 | SPRY2 (sprouty RTK signaling antagonist 2) | protein interactions | 10253 | 115 | 19 | 16036 | 1726 |
TCAF1,LASP1,PLSCR1,VANGL1,TESK1,UBASH3B,GNE,ADAMTSL4,NUBP1,SH3KBP1,C19orf66,ZFP36,CAB39,EGLN3,FAIM,SPRY2,EGLN1,MDFI,FRS3 |
| 3.814e-02 | -3.27 | Mitotic Anaphase | REACTOME pathways | R-HSA-68882 | 172 | 26 | 8202 | 867 |
PLK1,ZWINT,CENPA,PSMB4,SPC25,PSME2,CENPI,PTTG1,CDC20,NDC80,CDCA8,PSMD10,PSME1,NUF2,CENPN,PSMA4,LMNA,PSMD1,PPP2R5A,CDCA5,BUB1,CENPE,NDE1,UBE2C,ESPL1,NUP85 |
| 3.816e-02 | -3.27 | circadian regulation of gene expression | biological process | GO:0032922 | 60 | 11 | 16441 | 1675 |
SIRT1,GFPT1,LGR4,BHLHE41,PPARA,PRKCDBP,HDAC1,CRY2,PER3,AHR,NCOA2 |
| 3.816e-02 | -3.27 | apoptotic mitochondrial changes | biological process | GO:0008637 | 60 | 11 | 16441 | 1675 |
PPIF,GCLM,SLC25A4,AKT1,DNM1L,GCLC,TP53,BAX,BCL2L1,AIFM2,IFI6 |
| 3.817e-02 | -3.27 | organic substance catabolic process | biological process | GO:1901575 | 1534 | 177 | 16441 | 1675 |
CASP3,GAA,HSPG2,AASS,CRYM,GNPDA1,CPT2,CNOT8,DNAJC3,CUL4B,HEXB,FBXO2,PSME1,CCNB1,OAT,HDAC6,SDC1,CALM2,TYMP,CYP1A1,PSMD1,ZFP36,FUT1,TINAGL1,ACOX2,APOBEC3G,ERAP2,CYP1B1,PLK1,FBXL16,SPATA18,ITCH,USP18,CDA,AGO4,CCNF,RNF19B,CYP4F3,CDK1,TRIM9,PLCH1,ENPP1,PLCG1,NEIL1,HPSE,DHTKD1,GLA,CAPN1,ALDH6A1,DNAJB2,CALM3,GNS,RPL39,BDH1,NEK2,PCYOX1,AHCY,ZRANB1,NCEH1,MYLIP,GAD1,PLCB2,MCCC2,CYP26B1,PRODH,CALM1,PYM1,PDE5A,TP53INP2,PSMA4,AMDHD1,DCP2,NUDT16,H1F0,FAAH,AURKA,YOD1,CTSA,PLD1,RNF146,XDH,USP43,PLA2G4A,UPF3B,PSME2,PTTG1,MVB12B,LPIN3,PRKACA,CYP39A1,CYP26A1,RAD23A,CYP4F11,KIF14,FABP6,PLCG2,DAB2IP,GOT1,ECE1,PDE4D,PHKA2,LGMN,NAGA,GM2A,CHP1,CTH,SIRT1,ENPP4,SEC61B,ERLEC1,AKT1,CDC20,SAT1,DNAJC10,ALDH3B1,IDE,ALDH5A1,ABHD12,WFS1,PEX2,PNPLA6,LTA4H,PINK1,ENO2,CIT,HAL,SDC4,BLVRB,ERI2,PSMD10,CTSZ,APOBEC3H,NOTUM,FBXO6,DNAJB9,WWP2,SGPL1,FUT2,ADORA1,RNF128,CTSC,PTEN,GALNS,FUT8,UBE2J1,ECI2,WWP1,ALDH7A1,ABCD1,CNOT6L,FAH,HMMR,PGM1,SHMT1,ALDH2,PSMB4,GUSB,AMFR,NUB1,UBE2A,OGDHL,FBXO9,BLVRA,RNPEP,CTSL,FUCA1,RPL12,ACADSB,CTSV,ERAP1,ARRB1,PGM2L1,ARSB,NDFIP1,UBE2C,ACOT7,DIS3L |
| 3.820e-02 | -3.26 | SOCS3 (suppressor of cytokine signaling 3) | protein interactions | 9021 | 71 | 13 | 16036 | 1726 |
IRS2,IGF1R,JAK1,IL6ST,NFKBIA,MAPK11,YES1,MAP3K5,TXNDC11,JAK3,LEPR,MAPK8IP1,RASA1 |
| 3.821e-02 | -3.26 | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 125 | 19 | 17775 | 1757 |
AMOTL2,ARAP3,TNIP1,EPAS1,TBC1D8B,TP53,ERBB2,PSME1,OTUD1,ZNF687,CARD8,SP100,COL6A1,GRIN2D,PLD1,PIM1,PIKFYVE,EPB41L4A,AHR |
| 3.831e-02 | -3.26 | Dlg4 (discs, large homolog 4 (Drosophila)) | protein interactions | 13385 | 272 | 39 | 16036 | 1726 |
CFAP61,NCKAP5,CDK17,AASS,ADCK5,SH3KBP1,SUSD2,PIK3AP1,A4GALT,ZDHHC12,FRAS1,RTKN2,SCN2A,PIKFYVE,MYRIP,SYTL3,RASGRP1,RIMS2,ARAP2,KIFC2,RAPGEF2,SNTB2,STRADB,DIAPH2,RUNX3,PYGO1,GALNT7,ABR,CACHD1,ENPP1,COQ10A,TMEM54,JAK1,AGBL5,PTBP3,IRF7,ZMIZ1,RAP1GAP,GAB1 |
| 3.836e-02 | -3.26 | GK/Ca_channel_bsu | interpro domains | IPR008145 | 26 | 6 | 18293 | 1814 |
MPP5,TJP3,DLG3,CACNB4,MPP1,DLG1 |
| 3.836e-02 | -3.26 | V$HIF1_Q5 | MSigDB lists | V$HIF1_Q5 | 234 | 32 | 17758 | 1761 |
LTBP1,DAP,CACNA2D2,GRK6,PHLPP1,PDGFB,HPCAL4,WEE1,BHLHE41,BCL6,TWIST1,KLF9,PIM1,CITED2,TIAM1,BTBD3,ITCH,PDK3,C15orf39,PRDX4,PTPRF,PITX2,ONECUT1,PTPRJ,FAM114A1,KLF11,PRIMA1,HMGA1,ATP1B3,ARPC2,USF2,AIFM3 |
| 3.836e-02 | -3.26 | V$MYOD_Q6 | MSigDB lists | V$MYOD_Q6 | 234 | 32 | 17758 | 1761 |
EMX1,FBLIM1,FRMD4A,ITGA6,SELL,PRKACA,PDGFB,SPTB,BEX2,CYP26A1,EPDR1,HDAC9,RNF220,CDH1,GATA2,FUT8,ERBB3,NEB,RIMS2,PCDH1,BCL9,ATP1B1,ITPR3,GNAS,PRKAG2,PTPRJ,ACADSB,SCG2,NR4A3,HMGA1,OSR1,DEF6 |
| 3.836e-02 | -3.26 | ST_INTERLEUKIN_4_PATHWAY | MSigDB lists | ST_INTERLEUKIN_4_PATHWAY | 26 | 6 | 17758 | 1761 |
IL13RA1,JAK1,AKT1,JAK3,INPP5D,PIK3CA |
| 3.836e-02 | -3.26 | VALK_AML_CLUSTER_1 | MSigDB lists | VALK_AML_CLUSTER_1 | 26 | 6 | 17758 | 1761 |
NR4A2,IRF7,FHL1,BHLHE41,LTBP3,MECOM |
| 3.836e-02 | -3.26 | BIOCARTA_VIP_PATHWAY | MSigDB lists | BIOCARTA_VIP_PATHWAY | 26 | 6 | 17758 | 1761 |
CALM2,CALM3,PLCG1,PRKAR2B,CALM1,NFKBIA |
| 3.836e-02 | -3.26 | YANG_BREAST_CANCER_ESR1_BULK_UP | MSigDB lists | YANG_BREAST_CANCER_ESR1_BULK_UP | 26 | 6 | 17758 | 1761 |
TMBIM6,TSPAN13,BLVRA,TSPAN1,COX6C,ABCG1 |
| 3.836e-02 | -3.26 | PID_RXR_VDR_PATHWAY | MSigDB lists | PID_RXR_VDR_PATHWAY | 26 | 6 | 17758 | 1761 |
THRB,NR4A1,THRA,ABCA1,RARG,PPARA |
| 3.839e-02 | -3.26 | pancreas-ampulla_of_Vater-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-ampulla_of_Vater-carcinoma-ductal_carcinoma | 47 | 9 | 17775 | 1757 |
GNAS,MAN2B2,CDH1,IQCE,PIK3CA,TP53,ANXA9,BLVRA,SCN3A |
| 3.839e-02 | -3.26 | soft_tissue-sarcoma | COSMIC cancer mutations | soft_tissue-sarcoma | 47 | 9 | 17775 | 1757 |
GNAS,CDKN2C,SS18,AKT1,RET,PIK3CA,TP53,ERBB2,IDH1 |
| 3.847e-02 | -3.26 | V$AP1FJ_Q2 | MSigDB lists | V$AP1FJ_Q2 | 260 | 35 | 17758 | 1761 |
CMAS,SORT1,IGFBP6,SCOC,TRIP10,CAMKK1,BLVRB,ETV5,CALM3,SLC20A1,PRKACA,S100A2,LTBP3,SIX4,ZNF385B,LMNA,CALM2,ITGB8,SHC3,KCNN4,SLC16A6,TAGLN2,WBP5,MDFI,SMARCA2,TRIM8,CALM1,FOS,MAP2,CORO1C,S100A5,GRIN2D,HS3ST3B1,UBE2C,TOB1 |
| 3.849e-02 | -3.26 | lower_leg | COSMIC cancer mutations | lower_leg | 175 | 25 | 17775 | 1757 |
ADAMTS2,AKT1,TACC1,RET,PIK3R1,TP53,ERBB2,COL7A1,TNS1,IDH1,AIP,GNA11,LMNA,HLA-A,KIF5B,EPHA10,PLCH1,PTPRJ,PTEN,FGFR2,PTK7,PIK3CA,PTPRE,ALDH3A2,MYO5A |
| 3.853e-02 | -3.26 | SFN (stratifin) | protein interactions | 2810 | 256 | 37 | 16036 | 1726 |
ARHGAP11A,LMO7,PPP1R2,DCAF7,PPFIBP2,TP53,PKP2,KIF23,ARHGEF16,HDAC9,KIF5B,WEE1,APLP2,ST5,RALGPS2,CYR61,OSBPL3,MKRN3,ZFP36,BAX,PLK4,TRIM62,ING1,AKT1,NR3C1,ITCH,SAV1,BCAR1,CDK1,IRS2,H1F0,SHROOM3,RND3,SIPA1L1,SH3BP4,PIK3C2B,MAP3K5 |
| 3.855e-02 | -3.26 | UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII) | protein interactions | 27089 | 57 | 11 | 16036 | 1726 |
ATP1A1,DDOST,CPT2,ATP5H,IQGAP1,NRG1,ATP1B1,LMAN1,ALDH3A2,OPTN,SGPL1 |
| 3.855e-02 | -3.26 | TMEM185A (transmembrane protein 185A) | protein interactions | 84548 | 57 | 11 | 16036 | 1726 |
CD109,CPNE2,EFR3A,TSPAN6,CSNK1G1,OSTF1,YES1,NCAM1,GNA11,STX3,NCS1 |
| 3.855e-02 | -3.26 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1451 | 168 | 16441 | 1675 |
LGR4,EPAS1,HEXB,RET,MORF4L2,CAMK1D,PDGFB,EPCAM,HSF2,GRHL1,NPNT,IL31RA,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,AHRR,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,TFAP4,CYR61,GATA2,MDFIC,MYDGF,WNT3A,NUP85,ELK3,RGMB,SALL4,STAT4,MYBL2,ELK1,TP53INP2,NFIB,NCOA3,ONECUT1,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,RARG,TMEM173,KLF7,GRHL2,ARMCX3,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CTH,SIRT1,AKT1,RIPK2,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,NRG1,IRF7,KLF5,GLIS3,ANXA3,NKX3-1,PINK1,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,TOX2,GTF2F2,TFAP2A,TRIM21,CITED2,TRIM62,NCOA2,NFE2L3,HES1,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,NR1D2,ACVRL1,NR4A3,ARRB1,HMGA1,GPER1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 3.856e-02 | -3.26 | USP20 (ubiquitin specific peptidase 20) | protein interactions | 10868 | 64 | 12 | 16036 | 1726 |
PLK1,FECH,SUN2,CALM1,N4BP3,ECI2,SYTL4,RAD17,PRKACA,SPRY2,CBX7,MDFI |
| 3.856e-02 | -3.26 | MARK2 (MAP/microtubule affinity-regulating kinase 2) | protein interactions | 2011 | 64 | 12 | 16036 | 1726 |
MAP3K3,FUCA1,KIF5B,RHOA,PINK1,AKT1,RAB11FIP2,SNTB2,KIF13B,UTRN,PHLPP1,GAB1 |
| 3.859e-02 | -3.25 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6791 | 706 | 17775 | 1757 |
ACACB,ADD1,IL15RA,MRPS15,AASS,AK7,SLC25A13,HEXB,RET,CACNA2D2,FBXO2,DHX8,NRG2,TGOLN2,SYTL4,ISOC2,DPP8,CA8,BARD1,CARD10,GRM5,CALM2,CDKN2C,MUC4,KIAA1107,UBE2T,CYP2S1,FUT1,SEMA3G,PIK3CD,TIAM1,MGAT5,NWD1,SPEF2,MTRF1L,TMEM151A,TFAP2C,PRKAR2B,LOXL2,F12,CYP4F3,COL12A1,ABR,PLCG1,DNM1L,ANKRD6,ATP7B,LIMK1,TRAF3IP1,NOD2,SERPINB6,GAB1,SCN5A,GGA1,ITGA6,MTL5,RAB23,SLC36A4,COX6C,MERTK,TTYH3,ELF3,GNS,TFAP4,FRY,FAM189A1,MEGF8,FLRT3,FAM13B,CADPS2,ALPK1,PANX2,SLC37A1,KIF20A,SALL4,STAT4,ELK1,SFXN5,GNA11,CYB5A,PTPRF,CACHD1,NCOA3,SLC4A4,ETS2,ITPR1,CLMN,NDE1,DRP2,SERPINB1,ZNF502,ADAMTS16,DOCK9,GRHL2,ACTR8,RGS20,PKP2,PRSS22,NUF2,MUC16,ST5,CDH1,SH3BP1,RTKN2,ARL4D,RASGEF1A,RAB27B,CDKN2D,SCN3A,MX1,CAMSAP3,SEC61B,COL6A2,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,ZNF618,IRS2,CORO1C,SLC9A6,AXL,INPP4B,PNPLA6,ISOC1,TNRC6C,ESRP1,OSGIN2,CTSZ,ANO9,PLPPR4,ETS1,NEO1,PDIA4,ADD3,ITGB8,IGSF9,SLC27A6,ANKS1B,CALD1,MGAT4A,ALG13,ZFAND4,PLEKHF1,ADAM15,WWP1,MAPK11,TPCN1,AMOTL2,PVRL4,PLSCR1,FAM160A1,FMN1,TACC1,RAPGEF2,PIK3R1,MRS2,EIF5A2,ELOVL3,CXorf57,SNTB1,CRISPLD2,GALNT3,PITX2,PLOD2,RAB11FIP2,SYT7,CENPE,ITGAV,OSR1,CMPK2,TLL2,TMEM131,UNKL,KIAA1462,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,HDAC6,NUP62CL,SPTB,SUSD2,RPS6KA2,SHC3,IL6ST,SLC44A1,MITF,ABCA2,DUSP10,NTN4,ANO4,TLN2,MYBL1,DDX59,NEB,CCDC38,ZNF462,PCGF5,MCTP1,CELSR2,CR2,ANLN,IDH1,SESN1,DZIP1L,PLEKHG6,HS6ST1,PLCH1,KCNMB4,MAP2,P4HA2,DOLPP1,KLF11,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PARP12,ZCCHC24,DNAJB2,ASAH1,CNTNAP2,NCKAP1,IL18R1,ANO1,TNS3,IGF1R,GATA2,FRAS1,KIF13B,EXOC8,MPHOSPH9,ABCC1,C9orf9,CYP26B1,CHSY3,PCDH1,RGMB,PCBP3,CORO2A,ZNF320,MGAT4B,G2E3,RASGRP2,FOXD2,EPN3,COQ10A,PVRL2,KBTBD2,ITGA7,PHLPP2,PRPS2,LTBP2,ATP1B3,SEMA3A,RNF146,USP43,NF2,UGP2,UPF3B,CTDSPL,TP53,ERBB2,SLC7A2,FAM198B,LPIN3,EMP2,STIL,CYP26A1,SYTL2,TTC21B,WDR44,LHX6,ZDHHC23,BCL6,CDH3,NOTCH3,OAS3,MINPP1,EGLN3,LMAN1,SCN2A,CTH,SULF2,CPD,SIRT1,TMTC1,ERLEC1,AKT1,CDC20,ACO1,DAG1,ATP13A2,DNAJC10,DUOX1,PRRT4,ABHD12,PTK7,ADAMTS14,IRF7,AIFM3,ZNF701,NDST3,ZMAT1,BIN1,COL9A3,PACSIN2,CDH22,MACC1,GABRG2,SELL,PSMD10,GDF15,LBR,VPS26A,H1FX,SH2D4A,CD109,ALPP,TFAP2A,FAM63A,SYK,TLE6,IGDCC4,HMMR,HES1,PSMB4,IFITM3,GUSB,AMFR,PPARA,MAML2,COL7A1,FNDC3A,BCAR1,BANK1,SERPINA1,FAT4,SCG2,CDCA7L,TMC5,HIPK3,ARHGEF9,PKIA,GOLGB1,DIS3L,SUN1,GAA,PPP4R4,HSPG2,SSH1,LGR4,VANGL1,ATP8A1,TAP1,PLXNA1,CENPN,SLC9A7,ANKS6,ELMO2,STIM1,PRICKLE3,PIK3CA,KCNS3,STEAP2,AOX1,ATRNL1,SNX16,IRF2,SMYD5,XKR8,ORAI2,SGCE,CASP9,KIF13A,TNS1,CCNF,ZFAND5,TP53I3,POR,ARHGEF26,PRIM1,AHRR,GDE1,PLK2,NKD1,BMP1,PRDM5,UNC5B,TANC2,LZTS1,FGD1,CDK17,MRC2,FRMD4A,TBC1D1,DGKQ,CALB2,SLC25A27,ISYNA1,S100A2,TNFRSF19,PSIP1,MECOM,DOPEY2,PIK3AP1,BDH1,AIM1,RUNDC3B,DAPK1,ADCK2,TMEM51,PRKG1,SORL1,CD70,CACNA1D,PIKFYVE,GPR161,RIMS2,TRAK2,IGSF3,GFPT1,FADS2,PRODH,B3GNT7,PRSS23,TBC1D8B,CALM1,ANO6,VEZT,ATP8B3,RASA1,FRMD4B,FAS,SLCO4A1,PRKAG2,FAAH,PELI2,MATN2,SLC4A3,AGBL5,FAM83D,SFMBT1,PCDH19,NR4A2,CDK18,CABIN1,PER3,PLIN3,MAP3K5,HOOK1,IFIH1,FRMPD3,PLA2G4A,SPRED1,TCTN2,REPS2,DLGAP5,CEP70,TRIP10,ST14,IQGAP1,RPS6KA1,CCDC110,ATP2C2,ZFYVE9,EPS8L2,APLP2,FAM46A,TRANK1,DAB2IP,PDE4D,EPHB4,PHKA2,MED30,ATG4D,MYO5B,DOCK4,COG2,CAPN6,LYRM1,UTRN,TMEM144,PRKCQ,PYGO1,ATP1B1,C15orf39,ALCAM,ATP10D,SP4,FZD7,ZNF469,NIN,NRG1,NR3C2,COBL,DENND5B,WASF3,NUDT6,DEPDC1,ATP9A,EPS8,PBX3,DNAH3,EFNB1,TEAD3,E2F7,PHF7,PTEN,FUT8,CD9,ATP8B1,ERBB3,CNPY3,SPRY2,SLC16A5,NCOA2,FARP2,RASGRF1,PDGFC,ZWINT,ALDH2,B3GNT2,ARAP2,ERMAP,ZKSCAN2,DIAPH2,FBXO9,LRRC1,GPLD1,CDK5RAP1,MAMDC4,FGFR2,TBX18,AMMECR1,ABCB1,ERAP1,PGM2L1,GRIN2D,ETAA1,WDR62,SLC25A38,NCAPG2,ARSB,ESPL1,OCLN,JARID2,ESYT2,EXPH5,CRYM,MPP5,ERP29,TRIM68,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,ZCCHC12,CEP78,ANKFN1,PHTF1,DLG1,POF1B,ANKRD12,SUN3,CTTN,MYH14,MYRIP,BTBD3,CYP1B1,TRIM8,ITCH,RGAG1,ARHGDIB,ROR1,ADRBK2,EDNRA,MAN2A2,ARHGEF19,CAPN1,PCSK5,NR2C2,ARAP3,PPP1R2,ZNF395,PYROXD2,ETV5,ABCG2,PM20D2,SAMD9,PHLPP1,ADAMTSL4,ZNF432,AIM1L,CA2,COL6A1,LIMCH1,C10orf54,NCEH1,ETV7,ALS2CL,CCDC88A,SNX7,ELK3,OXR1,GYLTL1B,RNF113A,HEATR5A,NUBP1,PDIK1L,C3orf58,MUM1L1,SOX13,GLCE,GNAS,ONECUT1,CGREF1,ALPK3,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,SNX30,KLF7,LMO7,NCKAP5,SORBS1,MORC4,COL18A1,IL27RA,MRAS,OSR2,ARHGEF16,SS18,ZNF687,CYP4F11,KIF14,FRYL,F2R,PDIA6,SCYL3,MAP3K3,GCA,PTPRU,ERBB2IP,CD40,DOCK5,ARHGAP35,BFSP1,PEX2,TLE1,SPTBN5,CYP2U1,ABCA1,LNP1,LIFR,GLIS3,FBLIM1,GCLM,SORT1,ARHGEF11,TGFBR1,AES,COL4A5,NOTUM,INTS8,TRMT2B,SBF1,HDAC9,KIF5B,LLGL2,A4GALT,BMP7,TOX2,RRBP1,KIAA0319,IQGAP3,CLIP2,MYO5A,PHF20L1,ASPM,RC3H2,MBNL3,LRRC66,TTC7A,RUNX3,LEPR,ARHGAP24,SWAP70,DHRS2,ARRB1,GRAMD1C,ZMIZ1,AHR,ABCG1,CD33 |
| 3.864e-02 | -3.25 | development of primary sexual characteristics | biological process | GO:0045137 | 203 | 29 | 16441 | 1675 |
SIRT1,REC8,COL9A3,NKX3-1,FZD4,ASPM,CENPI,SOX9,TFAP2C,TGFBR1,BCL2L1,FNDC3A,IDH1,SDC1,SIX4,PRDX4,SGPL1,CCND1,PITX2,LRRC6,HOXA9,CTSV,CST3,TOX2,BAX,ARRB1,OSR1,SOX8,TIPARP |
| 3.867e-02 | -3.25 | odontogenesis of dentin-containing tooth | biological process | GO:0042475 | 75 | 13 | 16441 | 1675 |
PITX2,SCN5A,RUNX2,CA2,NF2,STIM1,BMP7,ITGA6,LRP4,PPARA,BAX,CNNM4,HDAC1 |
| 3.867e-02 | -3.25 | toll-like receptor 9 signaling pathway | biological process | GO:0034162 | 75 | 13 | 16441 | 1675 |
MAPKAPK2,RPS6KA2,RIPK2,PIK3AP1,PELI2,RPS6KA1,NFKBIA,NOD2,IRF7,MAPK11,ELK1,DUSP4,FOS |
| 3.868e-02 | -3.25 | antigen processing and presentation of exogenous peptide antigen | biological process | GO:0002478 | 170 | 25 | 16441 | 1675 |
SEC23A,SEC61B,PSMB4,HLA-E,PSME2,HLA-F,TAP1,PDIA3,KIF23,PSMD10,PSME1,KIF11,PSMA4,HLA-A,DCTN6,CTSL,HLA-B,TAPBP,PSMD1,AP1M2,CTSV,ITGAV,HLA-C,CENPE,LGMN |
| 3.874e-02 | -3.25 | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | WikiPathways | WP732 | 17 | 5 | 4455 | 516 |
MAPKAPK2,RASGRF1,ELK1,ITPR1,RASGRP1 |
| 3.875e-02 | -3.25 | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | 77 | 13 | 17758 | 1761 |
PLK1,PSMD1,PSMB4,PSME2,PTTG1,CDC20,AURKA,PSMD10,PSME1,CCNB1,UBE2C,CDK1,PSMA4 |
| 3.875e-02 | -3.25 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | 77 | 13 | 17758 | 1761 |
CALM2,PCOLCE,COL6A2,GUSB,NPNT,COL6A1,CALM1,TP53,PRKCDBP,ADAM15,CALM3,COL18A1,CRTAP |
| 3.875e-02 | -3.25 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | 77 | 13 | 17758 | 1761 |
MDK,ALDH2,S100A11,SLC39A8,PLEKHO1,AHCY,GGH,PSME1,NTAN1,IDH1,LGALS3BP,RBMS2,CKS2 |
| 3.877e-02 | -3.25 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | 183 | 26 | 17758 | 1761 |
ARHGAP11A,FADS2,PAPSS2,CDC20,LITAF,FBXO2,CBX6,LOXL2,KIF11,STIL,NRP2,FZD6,PRIM1,TOP2A,PRRT4,TIMP3,CYR61,PAQR5,CDCA5,DBI,NEK2,CLMN,NCAPG2,ETV4,ESPL1,E2F8 |
| 3.877e-02 | -3.25 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 183 | 26 | 17758 | 1761 |
ARHGAP11A,CCNE2,DDB2,PCOLCE,FBXL16,CPT2,S100A4,CENPI,ANO6,RNF113A,NPC2,CCNF,BARD1,STIL,PRDX4,STIM1,ANKRD6,SPINT2,AURKA,MDFIC,ZMIZ1,MPHOSPH9,ACOT7,MYO5A,NXT2,CKS2 |
| 3.892e-02 | -3.25 | - | gene3d domains | 3.30.1520.10 | 50 | 10 | 9988 | 1080 |
SNX18,SGK3,SNX16,PIK3C2B,PLD1,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 3.897e-02 | -3.24 | leukotriene metabolic process | biological process | GO:0006691 | 32 | 7 | 16441 | 1675 |
MAPKAPK2,MGST2,LTA4H,RNPEP,SYK,CYP4F3,ABCC1 |
| 3.897e-02 | -3.24 | regulation of myelination | biological process | GO:0031641 | 32 | 7 | 16441 | 1675 |
WASF3,NRG1,AKT1,PTEN,KIF14,RARG,DLG1 |
| 3.897e-02 | -3.24 | metanephric nephron development | biological process | GO:0072210 | 32 | 7 | 16441 | 1675 |
HES1,OSR1,SOX8,LGR4,FMN1,PDGFB,SOX9 |
| 3.897e-02 | -3.24 | regulation of protein oligomerization | biological process | GO:0032459 | 32 | 7 | 16441 | 1675 |
SORL1,IDE,BMF,DNM1L,FAS,TP53,BAX |
| 3.907e-02 | -3.24 | MODULE_72 | MSigDB lists | MODULE_72 | 304 | 40 | 17758 | 1761 |
MYL9,PCOLCE,DNAJB2,ITGA6,PTTG1,CALB2,SOX9,TMX4,TRIB2,HMGXB4,SAC3D1,CHPF,TOP2A,BTG3,ST5,MDM1,HSF2,CDK16,PPP4R1,NEK2,IGFBP2,CKS2,GFPT1,PLK1,SMARCA2,SGCE,COL6A2,ZWINT,SEPT6,CDC20,PKMYT1,GTF2A2,ITPR3,PSMA4,PLCG1,GPRC5B,WFS1,TCEAL4,CCNB2,JARID2 |
| 3.908e-02 | -3.24 | REGULATION_OF_PHOSPHORYLATION | MSigDB lists | REGULATION_OF_PHOSPHORYLATION | 47 | 9 | 17758 | 1761 |
CCND1,CDKN2C,NF2,IL31RA,CDKN1B,RAD17,BARD1,CDKN2D,CCDC88A |
| 3.908e-02 | -3.24 | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | MSigDB lists | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | 47 | 9 | 17758 | 1761 |
SIVA1,IL6ST,NAT1,SELL,SLC20A1,HOOK1,TRIM68,NFIX,FAM69A |
| 3.908e-02 | -3.24 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | MSigDB lists | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | 47 | 9 | 17758 | 1761 |
CHSY3,B3GALT6,HSPG2,SDC4,HEXB,DSE,SDC1,ARSB,CHPF |
| 3.908e-02 | -3.24 | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | MSigDB lists | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | 47 | 9 | 17758 | 1761 |
GCLM,MBP,TXN,NQO1,GCLC,CDKN2D,GPX4,ABCC1,PRDX4 |
| 3.908e-02 | -3.24 | KENNY_CTNNB1_TARGETS_UP | MSigDB lists | KENNY_CTNNB1_TARGETS_UP | 47 | 9 | 17758 | 1761 |
SORBS1,CYR61,CTSC,PLK4,ETAA1,LOXL2,CCNB1,PKN1,GNA11 |
| 3.908e-02 | -3.24 | DELACROIX_RAR_TARGETS_UP | MSigDB lists | DELACROIX_RAR_TARGETS_UP | 47 | 9 | 17758 | 1761 |
PRSS8,CTGF,SAT1,AOX1,TNFRSF12A,PRSS22,HMGA1,CRABP2,DHRS3 |
| 3.908e-02 | -3.24 | MICROTUBULE_ASSOCIATED_COMPLEX | MSigDB lists | MICROTUBULE_ASSOCIATED_COMPLEX | 47 | 9 | 17758 | 1761 |
KIF5B,MAP2,KIF23,KIF11,CLIP2,RANBP9,APPBP2,ATG4A,ATG4D |
| 3.908e-02 | -3.24 | V$STAT5A_03 | MSigDB lists | V$STAT5A_03 | 243 | 33 | 17758 | 1761 |
SPRED1,HSPG2,VANGL1,KLHL13,CD274,DHRS3,MNS1,TMC1,PPP2R3A,NEO1,NPNT,DPYSL2,LMO4,FLRT3,TBCD,FAM63A,BCL6,PCYOX1,TINAGL1,PIM1,MYT1,TGIF1,LONRF3,S100A4,FBXO9,BCAR3,EPN3,PELI2,ITGA7,PTK7,NR4A3,C1orf43,TOB1 |
| 3.910e-02 | -3.24 | regulation of intracellular protein transport | biological process | GO:0033157 | 365 | 48 | 16441 | 1675 |
DDX58,TCAF1,TXN,PINK1,NFKBIE,THRA,RAB23,ERBB2,PSMD10,TGFBR1,IL18,PRKACA,BARD1,APC2,IL18R1,BCAP31,NOV,CDH1,SP100,DACT1,BMP7,CABP1,FAM20B,UBE2J1,SORL1,DAB2IP,MDFIC,WNT3A,MDFI,CHP1,SIRT1,HES1,RHOA,ERLEC1,PIK3R1,LITAF,NBPF3,PRKCQ,FZD7,CDK5R1,NUCB1,TMEM30A,NFKBIA,NRG1,YOD1,FZD5,TMEM173,PKIA |
| 3.914e-02 | -3.24 | potassium channel regulator activity | molecular function | GO:0015459 | 46 | 9 | 16491 | 1673 |
PIAS3,KCNMB4,KCNIP3,DLG1,SGK3,KCNS3,SGK1,RASA1,CHP1 |
| 3.917e-02 | -3.24 | Cyclin_N | pfam domains | PF00134 | 32 | 7 | 16629 | 1696 |
CCNE2,CCNI,CCNJL,CCND1,CCNF,CCNB1,CCNB2 |
| 3.925e-02 | -3.24 | IB | smart domains | SM00121 | 18 | 5 | 9131 | 997 |
NOV,IGFBP2,IGFBP6,CTGF,CYR61 |
| 3.929e-02 | -3.24 | LENAOUR_DENDRITIC_CELL_MATURATION_DN | MSigDB lists | LENAOUR_DENDRITIC_CELL_MATURATION_DN | 125 | 19 | 17758 | 1761 |
PPIF,ELK3,PLSCR1,PLAUR,S100A4,DHX8,ARHGDIB,SLC1A3,LHFPL2,IER3,MAPKAPK2,SERPINA1,ITPR1,NFKBIA,SORL1,IRF7,GLA,LGMN,LTA4H |
| 3.929e-02 | -3.24 | ZHU_CMV_ALL_DN | MSigDB lists | ZHU_CMV_ALL_DN | 125 | 19 | 17758 | 1761 |
COL6A2,NR3C1,ACO1,FBLN1,LMNA,CCND1,TFAP4,WEE1,TIMP3,IGF1R,FAM46A,TSPAN6,IL6ST,MITF,TFAP2A,SERPINB6,IGFBP2,AHR,CYP1B1 |
| 3.933e-02 | -3.24 | regulation of cellular response to oxidative stress | biological process | GO:1900407 | 53 | 10 | 16441 | 1675 |
SIRT1,TXN,PINK1,FBLN5,AKT1,STK26,BMP7,NR4A3,HDAC6,HSPB1 |
| 3.936e-02 | -3.24 | RB in Cancer | WikiPathways | WP2446 | 87 | 16 | 4455 | 516 |
CCNE2,SMARCA2,TP53,ANLN,CCNB1,BARD1,CDK1,PRIM1,CCND1,TOP2A,WEE1,DCK,PLK4,HDAC1,CDKN1B,CCNB2 |
| 3.936e-02 | -3.23 | ZBTB16 (zinc finger and BTB domain containing 16) | protein interactions | 7704 | 123 | 20 | 16036 | 1726 |
MX1,MAP3K3,CASP3,CCDC109B,LMTK3,CEP70,PLSCR1,NR3C1,GNE,TP53,HDAC6,FAM101B,CDK1,SH2D4A,HDAC9,GATA2,ATP7B,BCL6,HDAC1,SPRY2 |
| 3.937e-02 | -3.23 | small_intestine-duodenum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-duodenum-carcinoma-adenocarcinoma | 33 | 7 | 17775 | 1757 |
GNAS,CDKN2C,ERBB2,AKT1,RET,PIK3CA,TP53 |
| 3.937e-02 | -3.23 | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | 33 | 7 | 17775 | 1757 |
ERBB2,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53 |
| 3.943e-02 | -3.23 | Leptin signaling pathway | WikiPathways | WP2034 | 60 | 12 | 4455 | 516 |
CCND1,PLCG1,RHOA,AKT1,JAK1,PIK3R1,BAX,ERBB2,BCL2L1,ELK1,LEPR,SOCS3 |
| 3.946e-02 | -3.23 | NOD1/2 Signaling Pathway | REACTOME pathways | R-HSA-168638 | 31 | 7 | 8202 | 867 |
MAPK11,RIPK2,CASP4,ITCH,CASP9,MAPK12,NOD2 |
| 3.950e-02 | -3.23 | protein phosphatase activator activity | molecular function | GO:0072542 | 8 | 3 | 16491 | 1673 |
CALM3,CALM2,CALM1 |
| 3.950e-02 | -3.23 | cAMP-dependent protein kinase inhibitor activity | molecular function | GO:0004862 | 8 | 3 | 16491 | 1673 |
PRKAR2B,PRKAG2,PKIA |
| 3.950e-02 | -3.23 | neurotrophin TRK receptor binding | molecular function | GO:0005167 | 8 | 3 | 16491 | 1673 |
EFNA5,PLCG1,PIK3R1 |
| 3.950e-02 | -3.23 | cytidine deaminase activity | molecular function | GO:0004126 | 8 | 3 | 16491 | 1673 |
APOBEC3H,APOBEC3G,CDA |
| 3.955e-02 | -3.23 | human chr14q32.1 | chromosome location | human chr14q32.1 | 11 | 3 | 26250 | 1887 |
FBLN5,SERPINA1,LGMN |
| 3.955e-02 | -3.23 | human chr4q31.1 | chromosome location | human chr4q31.1 | 11 | 3 | 26250 | 1887 |
GALNT7,SCOC,NR3C2 |
| 3.955e-02 | -3.23 | human chr8q21 | chromosome location | human chr8q21 | 11 | 3 | 26250 | 1887 |
WWP1,RIPK2,OSGIN2 |
| 3.956e-02 | -3.23 | ER to Golgi transport vesicle | cellular component | GO:0030134 | 69 | 12 | 17570 | 1756 |
HLA-B,SEC23A,SERPINA1,CTSC,HLA-E,HLA-F,CTSZ,COL7A1,HLA-C,LMAN1,MCFD2,HLA-A |
| 3.956e-02 | -3.23 | V$E2F_Q4_01 | MSigDB lists | V$E2F_Q4_01 | 226 | 31 | 17758 | 1761 |
ARHGAP11A,IER5L,ADAMTS2,DDB2,FBXO9,ERBB2IP,PKMYT1,NRP2,PRIM1,WEE1,E2F7,ZNF687,GPRC5B,DPYSL2,DCK,ZNF367,HOXA9,BMP7,RANBP1,PLK4,SFMBT1,AGFG2,KLF5,HMGA1,WDR62,CITED2,TIAM1,ETV4,NR3C2,E2F8,MELK |
| 3.958e-02 | -3.23 | MODULE_98 | MSigDB lists | MODULE_98 | 384 | 49 | 17758 | 1761 |
CCNE2,FOXM1,PTTG1,SOX9,NDC80,KIF23,PSMD10,CCNB1,BARD1,PHLDA1,H1FX,RAD23A,TOP2A,CDKN2C,WEE1,APLP2,HSF2,TFAP2A,GTF2F2,NEK2,BUB1,RFX5,CITED2,MYT1,PLK1,TGIF1,ZWINT,CENPA,AKT1,BCL9,MYBL2,UBE2A,RUNX3,GTF2A2,FOS,CDK1,PSMA4,PRIM1,FOXD2,MAP2,HNRNPH2,DCK,STK38,TLE1,CSTF2,HDAC1,CENPE,CCNB2,ESPL1 |
| 3.958e-02 | -3.23 | Mito_carr | pfam domains | PF00153 | 53 | 10 | 16629 | 1696 |
SLC25A48,SLC25A24,SLC25A4,SLC25A13,SLC25A27,SLC25A5,SLC25A30,SLC25A43,SLC25A38,SLC25A36 |
| 3.965e-02 | -3.23 | PX | smart domains | SM00312 | 43 | 9 | 9131 | 997 |
SNX18,SGK3,SNX16,PIK3C2B,PLD1,SNX10,SNX12,SNX30,SNX7 |
| 3.968e-02 | -3.23 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | 117 | 18 | 17758 | 1761 |
PCOLCE,ARHGEF11,ARHGDIB,LPIN3,DDR1,CASP4,SH3KBP1,LGALS3BP,PRICKLE3,COL6A1,CAB39,TRIM21,DAB2IP,FHL1,IFIT1,SNX10,OSGIN1,XDH |
| 3.968e-02 | -3.23 | ENZYME_INHIBITOR_ACTIVITY | MSigDB lists | ENZYME_INHIBITOR_ACTIVITY | 117 | 18 | 17758 | 1761 |
TIMP2,PPP1R2,CDKN1C,IQGAP1,DNAJC3,MAPK8IP1,SOCS3,CDKN2C,CABP1,SPINT2,CST3,ARRB1,CDKN1B,TWIST1,SERPINI1,SERPINB6,CDKN2D,PKIA |
| 3.968e-02 | -3.23 | ANTI_APOPTOSIS | MSigDB lists | ANTI_APOPTOSIS | 117 | 18 | 17758 | 1761 |
GCLC,HTATIP2,GLO1,BCL2L1,GSTP1,CDK1,RASA1,FAS,SOCS3,IER3,IGF1R,SEMA4D,BAX,HDAC1,HSPB1,CDKN2D,HIPK3,IFI6 |
| 3.973e-02 | -3.23 | Neural Crest Differentiation | WikiPathways | WP2064 | 101 | 18 | 4455 | 516 |
HES1,MBP,HDAC11,SOX9,HDAC6,ETS1,FGF19,HDAC9,CDH1,FGFR2,BMP7,MITF,TFAP2A,HDAC1,TWIST1,NOTCH3,WNT3A,DVL2 |
| 3.975e-02 | -3.23 | V$POU3F2_02 | MSigDB lists | V$POU3F2_02 | 252 | 34 | 17758 | 1761 |
FRMD4A,CHCHD7,GABRG2,PBX3,HPCAL4,TEAD3,LMNA,NEO1,HDAC9,PDGFA,FOXP2,MDM1,ADD3,PTEN,CYR61,XYLT2,LMO4,LHX6,MITF,DIXDC1,SCN2A,MYT1,DGKG,SMARCA2,ING1,PIK3R1,OGDHL,TFAP2C,NFIX,TAPBP,SP6,MAL2,SEMA3A,NXT2 |
| 3.975e-02 | -3.23 | V$LYF1_01 | MSigDB lists | V$LYF1_01 | 252 | 34 | 17758 | 1761 |
ENO2,IGFBP6,RASA2,NRG2,TNFRSF19,ATP6V0B,IGF1R,RALGPS2,CALD1,XYLT2,FUT8,EPB41L4B,PLCB2,NCOA2,ZNF462,HES1,SLC39A8,PANK1,SYNE2,SERTAD3,FURIN,PRICKLE1,TFAP2C,PELI3,PTPRF,PITX2,ITGA7,BMP1,SERPINI1,ANXA9,NRGN,RARG,NR3C2,JARID2 |
| 3.976e-02 | -3.22 | monovalent inorganic cation homeostasis | biological process | GO:0055067 | 114 | 18 | 16441 | 1675 |
CLCN3,ATP1B1,RAB38,SLC9A2,SLC9A7,ATP6V0B,SCNN1A,ATP1A1,CA2,SLC4A4,SLC9A6,SLC4A3,SGK3,SGK1,RAB20,ATP1B3,SLC12A2,CHP1 |
| 3.976e-02 | -3.22 | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | 175 | 25 | 17758 | 1761 |
IER5L,LZTFL1,MBP,REPS2,ZNF395,TESK2,TNS1,PTGFRN,MERTK,POR,TMCC3,CD109,CPNE2,SLC6A6,SWAP70,RPS6KA2,IGF1R,LRRC6,ITGB8,NGFRAP1,PPM1H,WWP1,TSPAN13,GEM,C1orf43 |
| 3.976e-02 | -3.22 | GSE13411_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_NAIVE_VS_MEMORY_BCELL_UP | 175 | 25 | 17758 | 1761 |
RASGRF1,RUNX2,NQO1,SPC25,ZNF395,TSC22D3,C3orf52,EPHA4,EIF5A2,C5orf30,STMN3,NCKAP1,CD40,MFAP3L,SLC6A6,PTPRJ,H1F0,KLF3,PLK4,CCDC82,LIFR,NDST3,HIPK3,NEB,RBMS2 |
| 3.976e-02 | -3.22 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 175 | 25 | 17758 | 1761 |
ADD1,SEPT6,SYNE2,SYBU,EZR,CR2,AES,GTF3A,TRIB2,ITPR3,OPTN,PRIM1,STK17A,CCDC92,BANK1,GNB5,AKR1B1,TLE1,FAM117A,TSPAN13,PIK3C2B,TRAF5,RASGRP1,SMAGP,FAM69A |
| 3.981e-02 | -3.22 | superpathway of melatonin degradation | BIOCYC pathways | HUMAN_PWY-6402 | 11 | 4 | 907 | 115 |
CYP2U1,POR,CYP2S1,CYP1B1 |
| 3.988e-02 | -3.22 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | MSigDB lists | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | 62 | 11 | 17758 | 1761 |
PLK1,CEP70,CNTRL,NEK2,PLK4,TUBG1,PRKAR2B,CCNB1,CEP41,PRKACA,CDK1 |
| 3.988e-02 | -3.22 | BRUNO_HEMATOPOIESIS | MSigDB lists | BRUNO_HEMATOPOIESIS | 62 | 11 | 17758 | 1761 |
RCN1,NOV,CD55,CTSC,H1F0,CD9,SESN1,REPS1,DAG1,S100A6,PRDX4 |
| 3.988e-02 | -3.22 | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP | MSigDB lists | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP | 62 | 11 | 17758 | 1761 |
GALNT3,ACACB,PHF20L1,CLCN3,ZNF823,COQ10B,FOSB,NR4A2,KLF11,MAFF,FRMD4B |
| 3.993e-02 | -3.22 | digestive tract development | biological process | GO:0048565 | 138 | 21 | 16441 | 1675 |
EPB41L5,PDGFC,LGR4,THRA,ITGA6,RET,NCKAP1,SAV1,CCNB1,NPHP3,FOXL1,PDGFA,CYP1A1,FAT4,FGFR2,GATA2,DACT1,MEGF8,KLF5,COBL,PCSK5 |
| 3.994e-02 | -3.22 | regulation of glomerular mesangial cell proliferation | biological process | GO:0072124 | 8 | 3 | 16441 | 1675 |
PDGFA,PDGFB,BMP7 |
| 3.994e-02 | -3.22 | platelet dense granule organization | biological process | GO:0060155 | 8 | 3 | 16441 | 1675 |
RAB38,F2R,ABCA1 |
| 3.994e-02 | -3.22 | regulation of protein heterodimerization activity | biological process | GO:0043497 | 8 | 3 | 16441 | 1675 |
DAB2IP,NRG1,BAX |
| 3.994e-02 | -3.22 | positive regulation of protein exit from endoplasmic reticulum | biological process | GO:0070863 | 8 | 3 | 16441 | 1675 |
SORL1,BCAP31,TMEM30A |
| 3.994e-02 | -3.22 | intracellular sterol transport | biological process | GO:0032366 | 8 | 3 | 16441 | 1675 |
NPC2,ABCA1,ABCG1 |
| 3.994e-02 | -3.22 | sebaceous gland development | biological process | GO:0048733 | 8 | 3 | 16441 | 1675 |
TFAP2C,CBX7,ZDHHC21 |
| 3.994e-02 | -3.22 | positive regulation of natural killer cell differentiation | biological process | GO:0032825 | 8 | 3 | 16441 | 1675 |
IL15,AXL,RASGRP1 |
| 3.994e-02 | -3.22 | regulation of T cell anergy | biological process | GO:0002667 | 8 | 3 | 16441 | 1675 |
HLA-B,PHLPP1,ITCH |
| 3.994e-02 | -3.22 | positive regulation of male gonad development | biological process | GO:2000020 | 8 | 3 | 16441 | 1675 |
CITED2,SEMA3A,SOX9 |
| 3.994e-02 | -3.22 | pyrimidine dimer repair | biological process | GO:0006290 | 8 | 3 | 16441 | 1675 |
SIRT1,CRY2,DDB2 |
| 3.994e-02 | -3.22 | regulation of macrophage apoptotic process | biological process | GO:2000109 | 8 | 3 | 16441 | 1675 |
SIRT1,IRF7,NOD2 |
| 3.994e-02 | -3.22 | regulation of lymphocyte anergy | biological process | GO:0002911 | 8 | 3 | 16441 | 1675 |
HLA-B,PHLPP1,ITCH |
| 3.994e-02 | -3.22 | negative regulation of immunoglobulin production | biological process | GO:0002638 | 8 | 3 | 16441 | 1675 |
TMBIM6,NDFIP1,BCL6 |
| 3.994e-02 | -3.22 | regulation of gamma-delta T cell activation | biological process | GO:0046643 | 8 | 3 | 16441 | 1675 |
SYK,SOX13,NOD2 |
| 3.994e-02 | -3.22 | amino sugar biosynthetic process | biological process | GO:0046349 | 8 | 3 | 16441 | 1675 |
GFPT1,UAP1,GNE |
| 3.994e-02 | -3.22 | regulation of high voltage-gated calcium channel activity | biological process | GO:1901841 | 8 | 3 | 16441 | 1675 |
CALM3,CALM2,CALM1 |
| 3.994e-02 | -3.22 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | biological process | GO:0008635 | 8 | 3 | 16441 | 1675 |
CASP3,CASP9,BAX |
| 3.994e-02 | -3.22 | heparin biosynthetic process | biological process | GO:0030210 | 8 | 3 | 16441 | 1675 |
NDST3,XYLT2,GLCE |
| 3.994e-02 | -3.22 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | GO:0031659 | 8 | 3 | 16441 | 1675 |
PIM1,AKT1,RGCC |
| 3.994e-02 | -3.22 | negative regulation of fatty acid transport | biological process | GO:2000192 | 8 | 3 | 16441 | 1675 |
IRS2,ACSL4,AKT1 |
| 3.994e-02 | -3.22 | negative regulation of cAMP-dependent protein kinase activity | biological process | GO:2000480 | 8 | 3 | 16441 | 1675 |
SIRT1,PRKAR2B,PKIA |
| 3.994e-02 | -3.22 | negative regulation of platelet aggregation | biological process | GO:0090331 | 8 | 3 | 16441 | 1675 |
SERPINE2,UBASH3B,PRKG1 |
| 3.994e-02 | -3.22 | forebrain neuroblast division | biological process | GO:0021873 | 8 | 3 | 16441 | 1675 |
WNT3A,FGFR2,ASPM |
| 3.994e-02 | -3.22 | nail development | biological process | GO:0035878 | 8 | 3 | 16441 | 1675 |
ITGA6,HOXC13,FZD6 |
| 3.994e-02 | -3.22 | positive regulation of double-strand break repair | biological process | GO:2000781 | 8 | 3 | 16441 | 1675 |
NUDT16,FOXM1,KDM4D |
| 3.994e-02 | -3.22 | negative regulation of fatty acid oxidation | biological process | GO:0046322 | 8 | 3 | 16441 | 1675 |
ACACB,AKT1,PLIN5 |
| 3.996e-02 | -3.22 | GSE14308_TH17_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH17_VS_INDUCED_TREG_UP | 192 | 27 | 17758 | 1761 |
SPEF2,ERLEC1,NFKBIE,TACC1,ZCCHC24,ITCH,BLVRB,HABP4,ABCG2,TIPRL,B4GALNT1,CCDC92,H1F0,XYLT2,FAM13B,AIM1,CCDC82,PLEKHF1,RHOBTB2,YOD1,CENPE,ETAA1,LRIF1,ST3GAL1,NEB,ZBTB33,ATP2B1 |
| 3.996e-02 | -3.22 | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDM_UP | 192 | 27 | 17758 | 1761 |
COL9A3,GNPDA1,RC3H2,MTL5,PTGER4,CBX6,COL7A1,OAT,DOCK5,SLC20A1,CHPF,TMEM63A,ARHGAP35,SOX13,RPS6KA2,C19orf66,DPYSL2,MKRN3,NFKBIA,NR4A3,TRPC1,BUB1,TMOD2,PIM1,DDX59,JARID2,TMEM131 |
| 3.996e-02 | -3.22 | GSE17580_TREG_VS_TEFF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_DN | 192 | 27 | 17758 | 1761 |
SLC37A1,EPAS1,TBC1D1,DAP,SYNE2,ARL4C,TCF7,ATP1B1,DOCK5,TXNDC11,STK17B,DENND2D,RASGRP2,ATP6V0B,DOPEY2,CDH1,ACVRL1,KBTBD2,STK38,SETD3,OTUB2,TAGLN2,C10orf54,FZD5,CDKN2D,SMAGP,ATG4D |
| 3.996e-02 | -3.22 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_UP | 192 | 27 | 17758 | 1761 |
ENPP4,HPS3,NFKBIE,ACTR8,STAT4,PIK3R1,ALCAM,RNF19B,SAC3D1,ATP13A2,TAF1B,C19orf66,SEMA4D,RBL1,CST3,ABCB1,TRIM21,ERAP1,RAB20,TAGLN2,ACOX2,PIM1,CTTN,HLA-C,ITPKA,SGCB,ST3GAL1 |
| 3.996e-02 | -3.22 | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDM_UP | 192 | 27 | 17758 | 1761 |
CASP3,MBP,HPS3,SHMT1,HJURP,CAPN6,PIK3R1,HMG20B,DIAPH2,DENND2D,BMP2K,ATP13A2,CDKN2C,DNAJC10,ONECUT1,ENPP1,DAZAP1,SESN3,ZNF704,CCDC82,EGFL7,ECE1,OAS3,SERPINB1,L1CAM,ACOT7,FAH |
| 3.996e-02 | -3.22 | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | 192 | 27 | 17758 | 1761 |
CENPA,KIF20A,PLSCR1,TMEM41B,PTGER4,ACO1,FBXO9,CDCA2,GPSM2,CCNF,ANLN,VASH1,CDK1,TNFSF9,SH3KBP1,BMP2K,ZDHHC21,WEE1,MSL1,CTSC,PLK4,CSTF2,ARF6,TIAM1,ESPL1,TRAK2,NR2C2 |
| 3.996e-02 | -3.22 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP | 192 | 27 | 17758 | 1761 |
FIGNL1,SWI5,KIF23,PRICKLE1,TNS1,TCF7,HMGN3,MGST2,DUSP4,FAM81A,MNS1,FANCI,DGKE,CD83,OPTN,EPCAM,WEE1,GDE1,NETO2,BCL6,TUBG1,AURKA,MAPK11,CEP41,TBC1D4,ZNF365,HOOK1 |
| 3.996e-02 | -3.22 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | 192 | 27 | 17758 | 1761 |
SIRT1,ACACB,COQ10B,CAST,HLA-F,PPFIBP2,ARL4C,PTGER4,TCF7,FOS,KBTBD11,FAM46C,GABARAPL1,PLCH1,MSL1,SLC16A6,GNPTAB,MGAT4A,ZFP36,TPST1,RYK,ARRB1,FAM117A,KLF11,TOB1,SMAGP,XKR8 |
| 3.996e-02 | -3.22 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 192 | 27 | 17758 | 1761 |
PODXL2,PTPRU,FOXJ2,SELL,AES,NENF,TP53I11,ATP10D,H1FX,CD83,MAN2A2,HLA-B,NUCB1,DOPEY2,RNF220,MSL1,PAIP2B,KLF3,PRKCDBP,GLB1L2,TAGLN2,PHKA2,CNPY3,HSPB1,JARID2,XKR8,FARP2 |
| 3.996e-02 | -3.22 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | 192 | 27 | 17758 | 1761 |
CCNI,SCN5A,DHX8,ARHGDIB,NUCB2,PSIP1,B4GALNT1,GPRC5B,FRY,ARTN,GATA2,RBL1,STIM1,PEX2,PLCG2,SRR,AOX1,ABCB1,MDH1,NRG1,HMGA1,PLOD3,CNPY3,MED22,RUSC1,KDELR1,ARHGEF4 |
| 3.996e-02 | -3.22 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | 192 | 27 | 17758 | 1761 |
PPIF,MBP,ADD1,ATP8A1,DAP,SEPT6,SELL,GLO1,ISYNA1,MORF4L2,RAD17,SNTB1,FAM101B,SESN1,RABGGTA,ANKRD10,SS18,ATP6V0B,RALGPS2,KCNN4,PHTF1,NR4A3,SGK1,FAM102A,PIK3CD,LMAN1,GM2A |
| 3.996e-02 | -3.22 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 27 | 17758 | 1761 |
MX1,CENPA,ADD1,TACC1,RPS6KA1,CDA,NDRG2,BCL2L1,CRABP2,SDC1,TEAD3,RHEB,CD83,BCAR3,ITGA3,KLF12,ARTN,IGF1R,KIF13B,PLCG2,VAT1,SERPINB6,LGMN,PLOD3,SMYD5,LTA4H,ALDH3A2 |
| 3.996e-02 | -3.22 | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDM_UP | 192 | 27 | 17758 | 1761 |
HMMR,PGM1,TIMP2,PARP12,HLA-E,DNAJC3,LPGAT1,FAM134A,CBX6,PDIA3,AES,TNS1,TEX2,CAMK1D,MCFD2,IFIT3,RASSF8,SYT7,NR1D2,CDCA7L,PLCG2,RANBP1,HDAC1,TSPAN13,S100A13,PRR15,RAB3IL1 |
| 3.996e-02 | -3.22 | GSE22886_NAIVE_VS_MEMORY_TCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_MEMORY_TCELL_UP | 192 | 27 | 17758 | 1761 |
REC8,PHF20L1,CD55,PINK1,NLRX1,ST14,CACNA2D2,BTN3A1,AES,TCF7,CACNB4,PHLDA1,EPN3,PGF,DCTN6,DAPK2,COL6A1,TRIOBP,ATP8B1,TLE1,CABIN1,NDE1,SULT2B1,MPHOSPH9,C9orf9,XDH,TLL2 |
| 3.996e-02 | -3.22 | SCHOEN_NFKB_SIGNALING | MSigDB lists | SCHOEN_NFKB_SIGNALING | 33 | 7 | 17758 | 1761 |
CDKN1B,CTGF,CYR61,NFKBIA,TPST1,PTGER4,BCL6 |
| 3.996e-02 | -3.22 | chr12p11 | MSigDB lists | chr12p11 | 33 | 7 | 17758 | 1761 |
PKP2,PRICKLE1,TMTC1,ITPR2,FAR2,BHLHE41,DENND5B |
| 3.996e-02 | -3.22 | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | 33 | 7 | 17758 | 1761 |
AMOTL2,PGM1,EGLN3,SLC20A1,RND3,RAPGEF2,EGLN1 |
| 3.996e-02 | -3.22 | SMALL_GTPASE_BINDING | MSigDB lists | SMALL_GTPASE_BINDING | 33 | 7 | 17758 | 1761 |
FGD6,DOCK4,ABCA1,RANBP9,RALBP1,RANBP1,FGD1 |
| 3.996e-02 | -3.22 | DUTTA_APOPTOSIS_VIA_NFKB | MSigDB lists | DUTTA_APOPTOSIS_VIA_NFKB | 33 | 7 | 17758 | 1761 |
FTH1,CD274,BCL2L1,FAS,IER3,TP53,BAX |
| 3.996e-02 | -3.22 | MODULE_522 | MSigDB lists | MODULE_522 | 33 | 7 | 17758 | 1761 |
TXN,SEC61B,GRK6,IL15RA,LGALS3,TRIP10,DNAJC3 |
| 3.996e-02 | -3.22 | FIRESTEIN_CTNNB1_PATHWAY | MSigDB lists | FIRESTEIN_CTNNB1_PATHWAY | 33 | 7 | 17758 | 1761 |
DGKH,PLK1,DAPK2,PDK3,PKN1,RPS6KA1,PLK4 |
| 3.999e-02 | -3.22 | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | MSigDB lists | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | 40 | 8 | 17758 | 1761 |
PLA2G4A,CD55,EPAS1,KCNK1,PLAUR,SDC4,IL18R1,IER3 |
| 3.999e-02 | -3.22 | TOMLINS_PROSTATE_CANCER_UP | MSigDB lists | TOMLINS_PROSTATE_CANCER_UP | 40 | 8 | 17758 | 1761 |
UAP1,GUSB,BDH1,DAPK1,CACNA1D,MANF,F2R,MCCC2 |
| 3.999e-02 | -3.22 | NEGATIVE_REGULATION_OF_GROWTH | MSigDB lists | NEGATIVE_REGULATION_OF_GROWTH | 40 | 8 | 17758 | 1761 |
CDKN2C,SERTAD3,BCL6,TP53,CDA,CDKN1B,CDKN2D,OSGIN1 |
| 3.999e-02 | -3.22 | WINNEPENNINCKX_MELANOMA_METASTASIS_DN | MSigDB lists | WINNEPENNINCKX_MELANOMA_METASTASIS_DN | 40 | 8 | 17758 | 1761 |
CTNNBIP1,DPYSL2,HOXA9,SPINT2,CST3,CRY2,ALDH3A2,PROM2 |
| 4.003e-02 | -3.22 | NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH | MSigDB lists | NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH | 150 | 22 | 17758 | 1761 |
CASP3,GCLC,HTATIP2,GLO1,BCL2L1,GSTP1,BARD1,CDK1,RASA1,FAS,SOCS3,IER3,IGF1R,SCG2,SEMA4D,BAX,HDAC1,PIM1,HSPB1,CDKN2D,IFI6,HIPK3 |
| 4.003e-02 | -3.22 | PSAT1 (phosphoserine aminotransferase 1) | protein interactions | 29968 | 37 | 8 | 16036 | 1726 |
DAZAP1,HSPG2,PSMD10,CAB39,TAGLN2,HSPB1,ARF4,SGPL1 |
| 4.003e-02 | -3.22 | GNA12 (guanine nucleotide binding protein (G protein) alpha 12) | protein interactions | 2768 | 37 | 8 | 16036 | 1726 |
GNAS,ARHGEF28,CDH1,ARHGEF11,RASA2,TEC,MAP3K5,F2R |
| 4.006e-02 | -3.22 | PTEN_C2 | pfam domains | PF10409 | 8 | 3 | 16629 | 1696 |
TNS3,TNS1,PTEN |
| 4.006e-02 | -3.22 | PI3K_C2 | pfam domains | PF00792 | 8 | 3 | 16629 | 1696 |
PIK3C2B,PIK3CD,PIK3CA |
| 4.006e-02 | -3.22 | regulation of focal adhesion assembly | biological process | GO:0051893 | 46 | 9 | 16441 | 1675 |
EPB41L5,PTPRJ,ACVRL1,PTEN,FMN1,CORO1C,SDC4,EFNA5,COL16A1 |
| 4.006e-02 | -3.22 | regulated secretory pathway | biological process | GO:0045055 | 46 | 9 | 16441 | 1675 |
ANXA3,GATA2,RAB11FIP2,STEAP2,RAB11FIP1,NR4A3,PIK3CD,S100A13,RASGRP1 |
| 4.006e-02 | -3.22 | response to antibiotic | biological process | GO:0046677 | 46 | 9 | 16441 | 1675 |
PLA2G4A,CASP3,CYP1A1,JAK1,CASP9,TP53,CDKN1B,SLC1A3,ETS1 |
| 4.006e-02 | -3.22 | regulation of cell-substrate junction assembly | biological process | GO:0090109 | 46 | 9 | 16441 | 1675 |
EPB41L5,PTPRJ,ACVRL1,PTEN,FMN1,CORO1C,SDC4,EFNA5,COL16A1 |
| 4.008e-02 | -3.22 | positive regulation of stress fiber assembly | biological process | GO:0051496 | 39 | 8 | 16441 | 1675 |
RHOA,NF2,CTGF,LIMK1,SDC4,RGCC,PRKCQ,EPHA1 |
| 4.008e-02 | -3.22 | regulation of lipid storage | biological process | GO:0010883 | 39 | 8 | 16441 | 1675 |
ACACB,NFKBIA,PPARA,ITGAV,ABCA1,PLIN5,EHD1,ABCG1 |
| 4.008e-02 | -3.22 | regulation of axon guidance | biological process | GO:1902667 | 39 | 8 | 16441 | 1675 |
SEMA6B,SEMA4D,MEGF8,SEMA3G,PLXNA1,WNT3A,SEMA3A,SEMA3B |
| 4.010e-02 | -3.22 | regulation of transmembrane transport | biological process | GO:0034762 | 383 | 50 | 16441 | 1675 |
SCN5A,TCAF1,LGALS3,FXYD3,CACNA2D2,CALM3,ANO9,PRKACA,CACNB4,PDGFB,ANO1,WWP2,CALM2,SNTA1,CA2,GNB5,STIM1,CABP1,PLCG2,KCNS3,DAPK1,DLG1,FXYD5,TWIST1,TSPAN13,PDE4D,TMEM37,CACNA1D,SCN2A,TPCN1,SCN3A,MYO5A,CHP1,PPIF,CLCN3,KCNJ12,RASGRF1,KCNIP3,AKT1,CALM1,ANO6,GRIN1,UTRN,ATP1B1,IRS2,NETO2,CAB39,STK39,FHL1,ATP1B3 |
| 4.016e-02 | -3.21 | regulation of fibroblast proliferation | biological process | GO:0048145 | 83 | 14 | 16441 | 1675 |
PDGFA,TGIF1,PDGFC,PEX2,TP53,BAX,DAB2IP,FTH1,CCNB1,ZMIZ1,PDGFB,GSTP1,FBLN1,S100A6 |
| 4.033e-02 | -3.21 | BDNF signaling pathway | WikiPathways | WP2380 | 144 | 24 | 4455 | 516 |
PRKAA2,CASP3,RASGRF1,ACACB,SORT1,AKT1,RPS6KA1,PIK3R1,GRIN1,ELK1,FOS,RANBP9,SIRPA,CDK5R1,PTPRF,IRS2,PLCG1,SHC3,DPYSL2,NFKBIA,DLG1,NCAM1,TIAM1,FRS3 |
| 4.052e-02 | -3.21 | FYN (FYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 2534 | 209 | 31 | 16036 | 1726 |
CASP3,CD55,IFITM3,NR3C1,PLAUR,ITCH,EPHA4,PIK3R1,GRIN1,PRKCQ,YES1,BCAR1,CDK1,DAG1,SH3KBP1,FAS,PTPRF,CNTNAP1,PLCG1,CDH1,FGFR2,MAP2,DOK4,PLCG2,ITPR1,ANKRD12,ADAM15,PDE4D,NCAM1,PTPRE,SYK |
| 4.053e-02 | -3.21 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | GO:0000982 | 324 | 43 | 16491 | 1673 |
RUNX2,EPAS1,SOX9,TP53,SIX4,ELF3,TFAP4,GRHL1,GATA2,BHLHE41,MITF,FOSB,TFAP2A,MYBL1,ETV4,NR2C1,NFE2L3,TGIF1,HES1,ELK3,KCNIP3,PLSCR1,NR3C1,FOXJ2,NR4A1,MYBL2,PPARA,TFAP2C,ELK1,FOS,NFIB,PITX2,NCOA3,ONECUT1,ETS2,PRDM5,NR4A3,OVOL1,IRF7,NR4A2,KLF5,E2F8,HOXC13 |
| 4.056e-02 | -3.20 | Mitotic Metaphase and Anaphase | REACTOME pathways | R-HSA-2555396 | 173 | 26 | 8202 | 867 |
PLK1,ZWINT,CENPA,PSMB4,SPC25,PSME2,CENPI,PTTG1,CDC20,NDC80,CDCA8,PSMD10,PSME1,NUF2,CENPN,PSMA4,LMNA,PSMD1,PPP2R5A,CDCA5,BUB1,CENPE,NDE1,UBE2C,ESPL1,NUP85 |
| 4.057e-02 | -3.20 | cytoplasmic vesicle part | cellular component | GO:0044433 | 561 | 69 | 17570 | 1756 |
SUN1,LAMP1,IL15RA,ATP8A1,BCL2L1,SYTL4,PDGFB,PHLDA1,APPBP2,SH3KBP1,PDGFA,ATP6V0B,AP1M2,N4BP3,RAB20,LMAN1,PACSIN1,RAB27B,MYRIP,SMAGP,LAMP3,MYO5B,LAMP2,SEC23A,CLCN3,FZD4,SNTB2,RAB38,MCFD2,GABARAPL1,GPRC5B,DNM1L,RAB11FIP1,NRGN,ARFGEF3,ANXA3,PACSIN2,CD63,HLA-F,HLA-E,RAB23,HLA-A,FZD6,MARCH8,ZNRF2,SNX18,CD9,CADPS2,HLA-C,WNT3A,GAD1,GPR161,KDELR1,SNX7,SYPL1,RAB3B,ATP8B3,C3orf58,HLA-B,SERPINA1,SYT7,RAB11FIP2,TMEM30A,ITPR1,ARRB1,GPER1,FZD5,TBC1D4,TMEM173 |
| 4.059e-02 | -3.20 | Asparagine N-linked glycosylation | REACTOME pathways | R-HSA-446203 | 181 | 27 | 8202 | 867 |
GFPT1,SEC23A,CMAS,GNE,MGAT4B,PDIA3,COL7A1,CTSZ,NANS,MCFD2,B4GALT4,MAN2A2,FUCA1,UAP1,DDOST,SERPINA1,CTSC,ALG13,MGAT4A,DOLPP1,FUT8,RPN2,CTSA,LMAN1,ST3GAL1,PPP6R1,MGAT5 |
| 4.061e-02 | -3.20 | developmental cell growth | biological process | GO:0048588 | 68 | 12 | 16441 | 1675 |
EMX1,FLRT3,IQGAP1,SLC9A6,SOX9,AURKA,EFNA5,ALCAM,SEMA3A,COBL,RARG,NRP2 |
| 4.061e-02 | -3.20 | aminoglycan catabolic process | biological process | GO:0006026 | 68 | 12 | 16441 | 1675 |
HMMR,GNS,FUCA1,HPSE,HSPG2,GUSB,GALNS,HEXB,SDC4,ARSB,SDC1,CHP1 |
| 4.061e-02 | -3.20 | nephron epithelium morphogenesis | biological process | GO:0072088 | 68 | 12 | 16441 | 1675 |
CTNNBIP1,HES1,FAT4,LGR4,FMN1,NPNT,SOX9,DLG1,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 4.072e-02 | -3.20 | Trafficking and processing of endosomal TLR | REACTOME pathways | R-HSA-1679131 | 13 | 4 | 8202 | 867 |
CTSL,LGMN,CNPY3,CTSV |
| 4.072e-02 | -3.20 | Repression of WNT target genes | REACTOME pathways | R-HSA-4641265 | 13 | 4 | 8202 | 867 |
HDAC1,TLE1,AES,TCF7 |
| 4.075e-02 | -3.20 | GSE22045_TREG_VS_TCONV_DN | MSigDB lists | GSE22045_TREG_VS_TCONV_DN | 167 | 24 | 17758 | 1761 |
HEBP1,GALNT12,NUB1,PDIA5,HMGN3,TMEM170B,SNTB1,SLC20A1,AMDHD1,LGALS3BP,STX3,PPP2R3A,SCML1,PLEKHG6,PRKAG2,ATP1A1,KIAA1107,COQ10A,TSPAN6,SECTM1,SPINT2,CTTN,PDE4D,HMGA1 |
| 4.075e-02 | -3.20 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | 167 | 24 | 17758 | 1761 |
EXPH5,TIMP2,CD55,SERPINE2,KLHL13,MPP1,TMEM41B,ITGA6,SLC11A2,TMEM170B,NUCB2,DDR1,STK17A,SCML1,HSF2,IGF1R,GPRC5B,CADPS2,PIK3CD,CEP41,NDFIP1,BTBD3,SNPH,PCSK5 |
| 4.076e-02 | -3.20 | FG_GAP | prosite domains | PS51470 | 19 | 5 | 11866 | 1235 |
ITGAV,ITGA3,ITGA7,ITGA6,GPLD1 |
| 4.077e-02 | -3.20 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176814 | 73 | 13 | 8202 | 867 |
PLK1,PSMD1,PSMB4,PSME2,PTTG1,CDC20,NEK2,PSMD10,PSME1,CCNB1,UBE2C,CDK1,PSMA4 |
| 4.077e-02 | -3.20 | Recruitment of mitotic centrosome proteins and complexes | REACTOME pathways | R-HSA-380270 | 73 | 13 | 8202 | 867 |
PLK1,CEP70,CNTRL,CEP78,NEK2,PLK4,TUBG1,PRKAR2B,NDE1,CCNB1,CEP41,PRKACA,CDK1 |
| 4.077e-02 | -3.20 | Centrosome maturation | REACTOME pathways | R-HSA-380287 | 73 | 13 | 8202 | 867 |
PLK1,CEP70,CNTRL,CEP78,NEK2,PLK4,TUBG1,PRKAR2B,NDE1,CCNB1,CEP41,PRKACA,CDK1 |
| 4.080e-02 | -3.20 | PDGF_ERK_DN.V1_DN | MSigDB lists | PDGF_ERK_DN.V1_DN | 142 | 21 | 17758 | 1761 |
MAP3K3,LTBP1,TGIF1,BCL9,PHLPP1,CCNF,APC2,ARHGEF16,DNAJB9,SAC3D1,LRRC6,CNTRL,NFKBIA,IRF2,FAM102A,CDKN1B,ARF6,PPP6R1,MAFF,SPRY2,CKS2 |
| 4.097e-02 | -3.19 | divalent metal ion transport | biological process | GO:0070838 | 263 | 36 | 16441 | 1675 |
CCDC109B,ATP2C2,CACNA2D2,ITPR2,CACNB4,SLC8B1,TMC1,NCS1,CTGF,STIM1,KCNN4,PLCG2,TRPC1,CNNM4,SELK,CACNA1D,TMEM37,SLC39A10,F2R,TPCN1,ATP2B1,ORAI2,SLC39A8,MRS2,ERO1A,ANO6,GRIN1,SLC11A2,ITPR3,CACHD1,ITPR1,SARAF,ITGAV,MCUR1,NIPA1,DENND5B |
| 4.098e-02 | -3.19 | Kit Receptor Signaling Pathway | WikiPathways | WP304 | 67 | 13 | 4455 | 516 |
SPRED1,PLCG1,AKT1,PTPRU,INPP5D,RPS6KA1,PIK3R1,MITF,YES1,TEC,SH3KBP1,RASA1,SOCS5 |
| 4.100e-02 | -3.19 | late endosome | cellular component | GO:0005770 | 191 | 27 | 17570 | 1756 |
LAMP2,LAMP1,MTM1,CLCN3,MMD,IFITM3,CD63,TMEM55B,RAPGEF2,SLC11A2,MVB12B,PARM1,M6PR,AP1AR,RNF128,ATP7B,SLC9A6,EXOC8,SNX16,PLD1,PIKFYVE,LGMN,RAB27B,F2R,TMEM9,MYO5A,STARD3NL |
| 4.101e-02 | -3.19 | Fc gamma R-mediated phagocytosis | KEGG pathways | hsa04666 | 92 | 16 | 6908 | 758 |
BIN1,PLA2G4A,WASF3,AKT1,INPP5D,PIK3R1,PLCG1,LIMK1,PLPP3,PLCG2,PIK3CA,PIK3CD,PLD1,ARPC2,ARF6,SYK |
| 4.101e-02 | -3.19 | Fc gamma R-mediated phagocytosis | KEGG pathways | ko04666 | 92 | 16 | 6908 | 758 |
BIN1,PLA2G4A,WASF3,AKT1,INPP5D,PIK3R1,PLCG1,LIMK1,PLPP3,PLCG2,PIK3CA,PIK3CD,PLD1,ARPC2,ARF6,SYK |
| 4.105e-02 | -3.19 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 184 | 26 | 17758 | 1761 |
LASP1,MRPS15,MPP1,ATP8A1,ITCH,CASP9,SELL,YES1,MGST2,ATP8B3,PTGFRN,ADRBK2,PDGFA,PPP2R5A,ETS2,RGS3,IMPAD1,DHTKD1,DIXDC1,CTTN,GEM,SERPINB1,BTBD3,SLC16A5,MCCC2,CPPED1 |
| 4.105e-02 | -3.19 | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | 184 | 26 | 17758 | 1761 |
SYPL1,CCDC109B,FBLN5,ENO2,AES,NENF,PRKRA,ERP29,AIP,PSIP1,EPS8L2,TMEM63A,KCNN4,PASK,FABP6,SPINT2,INPP4B,MDFIC,RGS14,TMEM159,SMYD5,TBC1D4,NDFIP1,TOB1,PKIA,ABCC1 |
| 4.105e-02 | -3.19 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | 184 | 26 | 17758 | 1761 |
SYPL1,CMAS,MRPL44,RHOA,PBK,C1GALT1C1,PSMD10,NDUFA4,SLC25A5,CDK1,DNAJB9,PRDX4,EPDR1,ATP1A1,UBE2T,TSPAN6,ALG13,DBI,BAX,CAB39,PPP2R3C,MANF,CITED2,PDIA6,CCNB2,SNX7 |
| 4.105e-02 | -3.19 | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 184 | 26 | 17758 | 1761 |
LASP1,SLC2A4,SORBS1,HSPG2,AKT1,EPAS1,PEX6,ADCK3,ACVR1C,KIF1C,TNS1,ZFAND5,ETS1,MAPK8IP1,PLIN5,EDNRA,APLP2,CARHSP1,WEE1,CYR61,BMP1,FAM195A,FHL1,PER3,GM2A,EHD1 |
| 4.106e-02 | -3.19 | V$AREB6_02 | MSigDB lists | V$AREB6_02 | 244 | 33 | 17758 | 1761 |
SCN5A,BMF,CAMKK1,IL13RA1,BCL2L1,FAM81A,DDR1,NRP2,WWP2,IRF2BPL,ITGA3,LLGL2,BCL6,VAT1,TAGLN2,ERBB3,EGLN3,DGKG,PVRL4,DOCK4,PCDH1,PIK3R1,TMEM151A,KIF13A,FOS,PITX2,PGM2L1,OSR1,DRP2,MAP3K5,SEMA3A,OCLN,RGMA |
| 4.127e-02 | -3.19 | skin-other-keratoacanthoma | COSMIC cancer mutations | skin-other-keratoacanthoma | 20 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 4.127e-02 | -3.19 | central_nervous_system-brain-glioma-oligodendroglioma | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma | 20 | 5 | 17775 | 1757 |
CDKN2C,NF2,IDH1,PTEN,TP53 |
| 4.127e-02 | -3.19 | keratoacanthoma | COSMIC cancer mutations | keratoacanthoma | 20 | 5 | 17775 | 1757 |
ERBB2,FGFR2,RET,PIK3CA,TP53 |
| 4.127e-02 | -3.19 | skin-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-Merkel_cell_carcinoma | 20 | 5 | 17775 | 1757 |
NF2,AKT1,PTEN,PIK3CA,TP53 |
| 4.163e-02 | -3.18 | CACTTTG,MIR-520G,MIR-520H | MSigDB lists | CACTTTG,MIR-520G,MIR-520H | 227 | 31 | 17758 | 1761 |
UNKL,DPYSL5,SPRED1,ARAP2,RUNX2,GRHL2,CELSR2,EPAS1,THRA,FURIN,ARL4C,TGOLN2,FNDC3A,ETS1,TP53INP2,EFNB1,VPS26A,NIN,DAPK2,NCOA3,KLF12,PLOD2,LIMK1,FLRT3,FAM13B,MAP3K9,NR4A3,FAM83D,SORL1,NR4A2,ABCA1 |
| 4.171e-02 | -3.18 | SRC_UP.V1_DN | MSigDB lists | SRC_UP.V1_DN | 159 | 23 | 17758 | 1761 |
SEMA6B,NFKBIE,PTGER4,PKP2,MAP3K6,STK17B,HOXB2,SPNS3,FRMD4B,SCRN2,RNF220,LYPD3,SLC2A6,PLK4,PCDH19,PIK3C2B,IFIT1,ACSL4,TMEM14A,IFI6,COBL,E2F8,CPPED1 |
| 4.171e-02 | -3.18 | CYTOSKELETAL_PROTEIN_BINDING | MSigDB lists | CYTOSKELETAL_PROTEIN_BINDING | 159 | 23 | 17758 | 1761 |
SUN2,SORBS1,ADD1,SSH1,ARFGEF1,EZR,ANLN,SPTB,MAPK8IP1,ATG4A,GABARAPL1,KIF5B,SHROOM3,CALD1,DLG1,FXYD5,ESPN,TMOD2,NDE1,MYLIP,SHROOM2,CCDC88A,ATG4D |
| 4.176e-02 | -3.18 | Semaphorin | interpro domains | IPR027231 | 20 | 5 | 18293 | 1814 |
SEMA6B,SEMA3G,SEMA3A,SEMA4D,SEMA3B |
| 4.176e-02 | -3.18 | IGFBP-like | interpro domains | IPR000867 | 20 | 5 | 18293 | 1814 |
IGFBP2,NOV,IGFBP6,CTGF,CYR61 |
| 4.176e-02 | -3.18 | CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_DN | MSigDB lists | CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_DN | 20 | 5 | 17758 | 1761 |
CALM2,CALM3,PDLIM3,ITPR1,CALM1 |
| 4.176e-02 | -3.18 | MANN_RESPONSE_TO_AMIFOSTINE_UP | MSigDB lists | MANN_RESPONSE_TO_AMIFOSTINE_UP | 20 | 5 | 17758 | 1761 |
DDB2,GDF15,S100A4,CASP4,RAD23A |
| 4.176e-02 | -3.18 | MODULE_439 | MSigDB lists | MODULE_439 | 20 | 5 | 17758 | 1761 |
PLK1,CCNB1,DNAJC3,MYBL2,IER3 |
| 4.176e-02 | -3.18 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | MSigDB lists | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | 20 | 5 | 17758 | 1761 |
ITPR2,ITPR3,ITPKA,DAG1,ITPR1 |
| 4.176e-02 | -3.18 | BIOCARTA_IGF1MTOR_PATHWAY | MSigDB lists | BIOCARTA_IGF1MTOR_PATHWAY | 20 | 5 | 17758 | 1761 |
IGF1R,AKT1,PTEN,PIK3R1,PIK3CA |
| 4.176e-02 | -3.18 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | 20 | 5 | 17758 | 1761 |
DUSP4,TRIB2,PHLDA1,PLK2,PKIA |
| 4.176e-02 | -3.18 | PID_WNT_CANONICAL_PATHWAY | MSigDB lists | PID_WNT_CANONICAL_PATHWAY | 20 | 5 | 17758 | 1761 |
PPP2R5A,FZD5,WNT3A,CSNK1G1,DVL2 |
| 4.176e-02 | -3.18 | ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM | MSigDB lists | ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM | 20 | 5 | 17758 | 1761 |
ATP1A1,ATP1B3,ATP1B1,ATP7B,ATP2B1 |
| 4.176e-02 | -3.18 | REACTOME_HS_GAG_DEGRADATION | MSigDB lists | REACTOME_HS_GAG_DEGRADATION | 20 | 5 | 17758 | 1761 |
HPSE,HSPG2,SDC1,GUSB,SDC4 |
| 4.176e-02 | -3.18 | DING_LUNG_CANCER_BY_MUTATION_RATE | MSigDB lists | DING_LUNG_CANCER_BY_MUTATION_RATE | 20 | 5 | 17758 | 1761 |
LMTK3,DDR1,ACVRL1,MAST4,TP53 |
| 4.176e-02 | -3.18 | MODULE_310 | MSigDB lists | MODULE_310 | 20 | 5 | 17758 | 1761 |
GCLM,MGST2,IDH1,GSTP1,GCLC |
| 4.180e-02 | -3.17 | phosphoprotein phosphatase activity | molecular function | GO:0004721 | 172 | 25 | 16491 | 1673 |
SSH3,MTM1,DLGAP5,SSH1,PPM1J,PTPRU,UBASH3B,PTPN9,CTDSPL,DUSP4,PHLPP1,SBF1,PTPRF,PTPRJ,PTEN,PLPP3,PHLPP2,PALD1,PPP4R1,DLG1,PPM1H,DUSP10,PTPRE,CTDSP2,CPPED1 |
| 4.186e-02 | -3.17 | TGANNYRGCA_V$TCF11MAFG_01 | MSigDB lists | TGANNYRGCA_V$TCF11MAFG_01 | 288 | 38 | 17758 | 1761 |
UNKL,CMAS,CAMKK1,IQGAP1,FBXO2,RNF182,RAB6A,GSTP1,VPS26A,FOXP2,ANKS1B,SLC16A6,TOX2,BCL6,TSPAN13,PIM1,DLG3,CLIP2,SNX10,DOCK4,ATL1,SEC23A,SMARCA2,SERTAD4,SNTB2,CBX6,ACO1,ATP1B1,SPTLC2,ARF4,GABARAPL1,NR4A3,PIK3C2B,NRG1,DRP2,RARG,TOB1,MAPK12 |
| 4.191e-02 | -3.17 | Apoptotic cleavage of cellular proteins | REACTOME pathways | R-HSA-111465 | 38 | 8 | 8202 | 867 |
CASP3,ADD1,CDH1,STK26,PRKCQ,BCAP31,LMNA,OCLN |
| 4.191e-02 | -3.17 | Collagen degradation | REACTOME pathways | R-HSA-1442490 | 38 | 8 | 8202 | 867 |
CTSL,MMP15,COL9A3,COL13A1,FURIN,COL18A1,COL16A1,COL12A1 |
| 4.198e-02 | -3.17 | SCARA3 (scavenger receptor class A, member 3) | protein interactions | 51435 | 44 | 9 | 16036 | 1726 |
SUN1,SUN2,LGALS3,LRIG1,GRAMD1C,TXNDC11,CMTM6,DNAJB9,HLA-A |
| 4.203e-02 | -3.17 | G0 and Early G1 | REACTOME pathways | R-HSA-1538133 | 25 | 6 | 8202 | 867 |
TOP2A,CCNE2,HDAC1,RBL1,CDK1,MYBL2 |
| 4.204e-02 | -3.17 | sensory perception of mechanical stimulus | biological process | GO:0050954 | 155 | 23 | 16441 | 1675 |
THRB,TPRN,CASP3,SERPINE2,FZD4,CRYM,HEXB,SLC1A3,TMC1,WFS1,LRIG1,TBX18,TFAP2A,ATP8B1,CDKN1B,SERPINB6,ESPN,ALDH7A1,MYH14,CACNA1D,SLC12A2,CDKN2D,SPRY2 |
| 4.207e-02 | -3.17 | DELASERNA_MYOD_TARGETS_DN | MSigDB lists | DELASERNA_MYOD_TARGETS_DN | 55 | 10 | 17758 | 1761 |
ADAMTS2,PTEN,CAPN6,DPYSL2,VASN,ERBB2IP,ITPR2,TTYH3,CYB5A,PRDX4 |
| 4.207e-02 | -3.17 | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | MSigDB lists | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | 55 | 10 | 17758 | 1761 |
MFI2,IL15,CTSC,HAPLN3,GNE,ELF5,ALDH1A3,SECTM1,ITPR2,XDH |
| 4.207e-02 | -3.17 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | MSigDB lists | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | 55 | 10 | 17758 | 1761 |
PLK1,CEP70,CNTRL,NEK2,PLK4,TUBG1,PRKAR2B,CEP41,PRKACA,CDK1 |
| 4.207e-02 | -3.17 | AGTTCTC,MIR-146A,MIR-146B | MSigDB lists | AGTTCTC,MIR-146A,MIR-146B | 55 | 10 | 17758 | 1761 |
DLGAP1,THRB,PHF20L1,PCDH1,VASN,PTGFRN,PRX,NRP2,STX3,KLF7 |
| 4.213e-02 | -3.17 | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | MSigDB lists | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | 126 | 19 | 17758 | 1761 |
IL15,USP18,PLAUR,LITAF,SELL,TNFSF9,CASP4,SOCS3,NFKBIA,RAB20,NFKBIZ,IRF7,IFIT1,OAS3,GEM,CMPK2,ST3GAL1,IFIH1,MAFF |
| 4.213e-02 | -3.17 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | MSigDB lists | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | 126 | 19 | 17758 | 1761 |
DOCK4,KIF20A,TP53,HMG20B,KIF23,PRKAR2B,DOCK5,PRKACA,KIF11,KIF5B,WEE1,GATA2,KLC3,IRF2,HDAC1,IRF7,MAFF,EHD1,DOCK9 |
| 4.215e-02 | -3.17 | LEE_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_UP | 176 | 25 | 17758 | 1761 |
UNKL,PINK1,FAM169A,ADCK3,CPT2,AMFR,OGDHL,C6orf106,NDRG2,ITPR2,F12,PHLPP1,AMDHD1,SGPL1,CYP4F11,CGREF1,BDH1,ENPP5,RUNDC3B,AOX1,CABIN1,ANXA9,ACOX2,MYRIP,DENND5B |
| 4.220e-02 | -3.17 | PPASE_TENSIN | prosite domains | PS51181 | 8 | 3 | 11866 | 1235 |
TNS1,TNS3,PTEN |
| 4.220e-02 | -3.17 | C2_TENSIN | prosite domains | PS51182 | 8 | 3 | 11866 | 1235 |
TNS1,TNS3,PTEN |
| 4.220e-02 | -3.17 | PI3K_C2 | prosite domains | PS51547 | 8 | 3 | 11866 | 1235 |
PIK3C2B,PIK3CD,PIK3CA |
| 4.221e-02 | -3.17 | histone acetyltransferase binding | molecular function | GO:0035035 | 26 | 6 | 16491 | 1673 |
CITED2,EPAS1,ETS1,TRIM68,TP53,NR4A3 |
| 4.224e-02 | -3.16 | GSE17721_12H_VS_24H_PAM3CSK4_BMDM_DN | MSigDB lists | GSE17721_12H_VS_24H_PAM3CSK4_BMDM_DN | 193 | 27 | 17758 | 1761 |
LAMP2,MBP,GCLC,STAT4,LPGAT1,UTRN,NDUFA4,MRAS,POMGNT1,HDAC6,MRPS36,ZFAND5,TCEAL8,PHLDA1,CYB5A,SNTA1,CTNNBIP1,CDK5RAP1,FAM111A,HLF,SESN3,BDH1,DBI,TSPAN13,MDH1,MAPK11,OSGIN1 |
| 4.224e-02 | -3.16 | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | 193 | 27 | 17758 | 1761 |
CCNI,ZWINT,PSMB4,PTPRU,GUSB,DAP,TMX4,PARP4,CDA,BTN3A2,VASH1,SLC25A5,GSTP1,GNA11,RABGGTA,FUCA1,MAPKAPK2,NUCB1,TAPBP,H1F0,STIM1,ATP5H,STK38,PLCG2,NEK2,ADAM15,USF2 |
| 4.224e-02 | -3.16 | PENG_RAPAMYCIN_RESPONSE_UP | MSigDB lists | PENG_RAPAMYCIN_RESPONSE_UP | 193 | 27 | 17758 | 1761 |
HMMR,OPLAH,ALDH2,TBC1D1,HLA-F,DRAP1,NDC80,TP53,HMG20B,AES,CD40,RNPEP,RNF19B,H1FX,TOP2A,FUCA1,PPP2R5A,TRANK1,JAK1,BCL6,UBE2J1,SORL1,IFIT1,CTTN,USF2,CTDSP2,TMEM131 |
| 4.224e-02 | -3.16 | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | 193 | 27 | 17758 | 1761 |
TIMP2,CCDC109B,CENPA,S100A11,SEPT6,ITGA6,EPS8,EZR,TNS1,NANS,NFIX,NOV,SH3BP1,TIMM8A,DOLPP1,PPP4R1,NR4A3,ABCD1,TMEM37,RGS14,PLCB2,NDUFA12,MYL12B,S100A6,RAB3IL1,JARID2,GCNT1 |
| 4.224e-02 | -3.16 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDM_DN | 193 | 27 | 17758 | 1761 |
EPB41L5,MFSD3,SYPL1,PARP12,TCTN2,RIPK2,MPP1,STAT4,USP18,SPATA13,TCF7,SAV1,BCAR3,DNAJC10,AP1M2,UAP1,TSPAN6,ITPR1,RAP2C,FAM13B,IRF2,TSPAN13,OAS3,RGS14,CMPK2,SNX10,PTGES |
| 4.224e-02 | -3.16 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | 193 | 27 | 17758 | 1761 |
ENPP4,MX1,SUN2,NFKBIE,IL15,TBC1D1,TAP1,COL18A1,SNN,OAT,HERC6,SLC20A1,ETS1,MERTK,PHLDA1,ANTXR1,PSMA4,GLCE,RPS6KA2,ARSG,CSF1,SLC2A6,ZRANB1,F2R,RNF146,KDELR1,TRAK2 |
| 4.224e-02 | -3.16 | GSE7764_NKCELL_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_DN | 193 | 27 | 17758 | 1761 |
CLCN3,ZNF395,PLEKHO1,SERTAD3,KIF23,EIF2AK1,CCNF,TRIB2,GTF2A2,MERTK,CYP4F3,RANBP9,AMZ2,TOP2A,PLCG1,BDH1,NEK2,ADAM15,GOT1,TMEM64,TECR,LGMN,PLIN3,CEP41,APOL2,SNX30,MYO5A |
| 4.224e-02 | -3.16 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 193 | 27 | 17758 | 1761 |
MAN2B2,SUN2,DDB2,SEC61B,ST14,DAP,BLVRB,CDA,NDRG2,CRABP2,CD83,BCAR3,FUCA1,RPL12,RPS6KA2,ITGA3,GNB5,PRCP,PLCG2,AKR1B1,VAT1,SERPINB6,PIM1,CTTN,LTA4H,GAB1,ALDH3A2 |
| 4.224e-02 | -3.16 | GSE17721_CTRL_VS_POLYIC_4H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_4H_BMDM_DN | 193 | 27 | 17758 | 1761 |
SHMT1,FBLN5,PARP12,NR3C1,CD82,NUB1,PARP4,TAP1,PDK3,DENND2D,TNFSF9,CASP4,CMTM6,PSMA4,ABR,MAPKAPK2,ENDOD1,CARHSP1,DOPEY2,PPP2R5A,ETS2,PIK3AP1,MITF,CDH3,OSTF1,GLCCI1,EHD1 |
| 4.224e-02 | -3.16 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | 193 | 27 | 17758 | 1761 |
DOCK4,ALDH2,EPAS1,TSPAN15,AMFR,CORO2A,RAPGEF2,DNAJC3,PYROXD2,NDRG2,FAM198B,CAMK1D,ETS1,ANTXR1,SPNS3,ANKRD29,ATP10D,TMCC3,RPS6KA2,SERPINA1,SLC16A6,BCL6,CD9,SGK1,LGMN,SERPINB1,PCSK5 |
| 4.238e-02 | -3.16 | regulation of ion transmembrane transport | biological process | GO:0034765 | 367 | 48 | 16441 | 1675 |
SCN5A,TCAF1,LGALS3,FXYD3,CACNA2D2,CALM3,ANO9,PRKACA,CACNB4,PDGFB,ANO1,WWP2,CALM2,SNTA1,GNB5,STIM1,CABP1,PLCG2,KCNS3,DAPK1,DLG1,FXYD5,TSPAN13,PDE4D,TMEM37,CACNA1D,SCN2A,TPCN1,MYO5A,SCN3A,CHP1,PPIF,CLCN3,KCNJ12,RASGRF1,KCNIP3,AKT1,CALM1,ANO6,GRIN1,UTRN,ATP1B1,IRS2,NETO2,CAB39,STK39,FHL1,ATP1B3 |
| 4.240e-02 | -3.16 | V$CMYB_01 | MSigDB lists | V$CMYB_01 | 236 | 32 | 17758 | 1761 |
SCN5A,ALDH6A1,CPEB4,HEBP1,CALM3,MORF4L2,PDGFB,SH3KBP1,VPS26A,B4GALNT1,CALM2,ADD3,PHF7,PIK3AP1,FAM13B,RANBP1,FAM63A,KLF9,MANF,CITED2,ETV4,DVL2,ZNF462,CALM1,CBX6,PITX2,SPINT2,AGBL5,KLF5,ARF6,NRGN,NR3C2 |
| 4.243e-02 | -3.16 | ER-associated ubiquitin-dependent protein catabolic process | biological process | GO:0030433 | 61 | 11 | 16441 | 1675 |
DNAJC10,SEC61B,ERLEC1,DNAJB2,AMFR,WFS1,UBE2J1,FBXO2,YOD1,FBXO6,DNAJB9 |
| 4.244e-02 | -3.16 | NEGATIVE_REGULATION_OF_CELL_CYCLE | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_CYCLE | 78 | 13 | 17758 | 1761 |
CDK5RAP1,CDKN2C,BTG3,CDKN1C,DHRS2,BMP7,DLG1,TP53,CDKN1B,RUNX3,CDKN2D,SESN1,MAPK12 |
| 4.244e-02 | -3.16 | DUAN_PRDM5_TARGETS | MSigDB lists | DUAN_PRDM5_TARGETS | 78 | 13 | 17758 | 1761 |
CD99,APOBEC3B,PIAS3,RUNX2,ENO2,ETS2,TP53,NLRC5,OVOL1,TINAGL1,S100A2,EDNRA,SOCS3 |
| 4.244e-02 | -3.16 | REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | REGULATION_OF_HYDROLASE_ACTIVITY | 78 | 13 | 17758 | 1761 |
CARD8,RALBP1,CASP9,TP53,BAX,FGD6,CDKN2D,PLCB2,AIFM3,F2R,IFI6,FGD1,EDNRA |
| 4.247e-02 | -3.16 | Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | GO:0038096 | 76 | 13 | 16441 | 1675 |
PLCG1,ELMO2,LIMK1,ITPR1,PIK3R1,PLCG2,PIK3CA,ITPR2,NCKAP1,YES1,ITPR3,ARPC2,SYK |
| 4.247e-02 | -3.16 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | biological process | GO:0002433 | 76 | 13 | 16441 | 1675 |
PLCG1,ELMO2,LIMK1,ITPR1,PIK3R1,PLCG2,PIK3CA,ITPR2,NCKAP1,YES1,ITPR3,ARPC2,SYK |
| 4.247e-02 | -3.16 | central_nervous_system-brain-glioma-ependymoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_II | 14 | 4 | 17775 | 1757 |
NF2,AKT1,IDH1,PTEN |
| 4.247e-02 | -3.16 | bone-chordoma | COSMIC cancer mutations | bone-chordoma | 14 | 4 | 17775 | 1757 |
SS18,IDH1,PIK3CA,TP53 |
| 4.247e-02 | -3.16 | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 4 | 17775 | 1757 |
AKT1,PTEN,PIK3CA,TP53 |
| 4.247e-02 | -3.16 | soft_tissue-small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-small_round_cell_tumour | 14 | 4 | 17775 | 1757 |
ERBB2,SS18,PIK3CA,TP53 |
| 4.247e-02 | -3.16 | endometriosis | COSMIC cancer mutations | endometriosis | 14 | 4 | 17775 | 1757 |
AKT1,PTEN,PIK3CA,TP53 |
| 4.247e-02 | -3.16 | small_round_cell_tumour | COSMIC cancer mutations | small_round_cell_tumour | 14 | 4 | 17775 | 1757 |
ERBB2,SS18,PIK3CA,TP53 |
| 4.247e-02 | -3.16 | adrenal_cortical_hyperplasia | COSMIC cancer mutations | adrenal_cortical_hyperplasia | 14 | 4 | 17775 | 1757 |
GNAS,ATP1A1,CACNA1D,AMER1 |
| 4.247e-02 | -3.16 | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 4 | 17775 | 1757 |
AKT1,PTEN,PIK3CA,TP53 |
| 4.254e-02 | -3.16 | protein import into nucleus | biological process | GO:0006606 | 107 | 17 | 16441 | 1675 |
HES1,SEC61B,AKT1,PIK3R1,TP53,PRICKLE1,PDIA3,DAG1,ZFYVE9,LMNA,NFKBIA,BCL6,F2R,JAK3,NUP85,TOB1,SYK |
| 4.254e-02 | -3.16 | single-organism nuclear import | biological process | GO:1902593 | 107 | 17 | 16441 | 1675 |
HES1,SEC61B,AKT1,PIK3R1,TP53,PRICKLE1,PDIA3,DAG1,ZFYVE9,LMNA,NFKBIA,BCL6,F2R,JAK3,NUP85,TOB1,SYK |
| 4.254e-02 | -3.16 | protein targeting to nucleus | biological process | GO:0044744 | 107 | 17 | 16441 | 1675 |
HES1,SEC61B,AKT1,PIK3R1,TP53,PRICKLE1,PDIA3,DAG1,ZFYVE9,LMNA,NFKBIA,BCL6,F2R,JAK3,NUP85,TOB1,SYK |
| 4.264e-02 | -3.15 | GROSS_HYPOXIA_VIA_ELK3_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_DN | 151 | 22 | 17758 | 1761 |
LAMP2,TGIF1,ITGA6,SAT1,PTGER4,VWA1,IL13RA1,DUSP4,FOS,ETS1,SLC20A1,ACAP2,CTGF,CYR61,ZFP36,PLK2,NFKBIA,FGD6,PRKCDBP,ACSL4,SPRY2,CTH |
| 4.266e-02 | -3.15 | CCTNTMAGA_UNKNOWN | MSigDB lists | CCTNTMAGA_UNKNOWN | 118 | 18 | 17758 | 1761 |
ZNF462,SDC4,FBXO2,CBX6,PRICKLE1,TGFBR1,OSR2,VASH1,LMNA,MMP15,ADD3,ITGA3,AXL,PELI2,DLG1,RFX5,KLF7,GCNT1 |
| 4.270e-02 | -3.15 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 202 | 30 | 16036 | 1726 |
MAP3K3,MBP,ARHGEF28,LGALS3,EPAS1,CALM1,CASP9,PIK3R1,TP53,PSMD10,TGFBR1,CCNB1,HDAC6,ZFAND5,SESN1,CDK1,DCP2,OPTN,GABARAPL1,FAS,RAD23A,ENPP1,LLGL2,CEP78,PIK3CA,NOD2,TRIM21,EGLN3,HSPB1,DVL2 |
| 4.288e-02 | -3.15 | transition metal ion homeostasis | biological process | GO:0055076 | 131 | 20 | 16441 | 1675 |
MFI2,EPAS1,ABCG2,ACO1,TTC7A,EIF2AK1,SLC11A2,FTH1,NUBP1,SFXN5,STEAP1,NEO1,FECH,ATP6V0B,APLP2,ATP7B,STEAP2,SLC39A10,NDFIP1,CYBRD1 |
| 4.291e-02 | -3.15 | Tyr_kinase_ephrin_rcpt | interpro domains | IPR016257 | 14 | 4 | 18293 | 1814 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.291e-02 | -3.15 | Ephrin_rcpt_lig-bd_dom | interpro domains | IPR001090 | 14 | 4 | 18293 | 1814 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.291e-02 | -3.15 | Neurexin-like | interpro domains | IPR003585 | 14 | 4 | 18293 | 1814 |
CNTNAP1,CNTNAP2,SDC1,SDC4 |
| 4.291e-02 | -3.15 | Eph_TM | interpro domains | IPR027936 | 14 | 4 | 18293 | 1814 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.291e-02 | -3.15 | Cyt_B5-like_heme/steroid-bd | interpro domains | IPR001199 | 14 | 4 | 18293 | 1814 |
FADS2,NENF,CYB5A,PGRMC1 |
| 4.291e-02 | -3.15 | Tyr_kinase_rcpt_V_CS | interpro domains | IPR001426 | 14 | 4 | 18293 | 1814 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.291e-02 | -3.15 | MATZUK_OVULATION | MSigDB lists | MATZUK_OVULATION | 14 | 4 | 17758 | 1761 |
SIRT1,PDE4D,IL6ST,NR2C2 |
| 4.291e-02 | -3.15 | SABATES_COLORECTAL_ADENOMA_SIZE_DN | MSigDB lists | SABATES_COLORECTAL_ADENOMA_SIZE_DN | 14 | 4 | 17758 | 1761 |
C2orf72,PDE4D,RCAN3,GNPTAB |
| 4.291e-02 | -3.15 | BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN | 14 | 4 | 17758 | 1761 |
HLF,RUNDC3B,FAH,ABCG2 |
| 4.291e-02 | -3.15 | chr10p14 | MSigDB lists | chr10p14 | 14 | 4 | 17758 | 1761 |
DHTKD1,FRMD4A,OPTN,SEPHS1 |
| 4.291e-02 | -3.15 | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | MSigDB lists | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | 14 | 4 | 17758 | 1761 |
CD99,AES,CCNF,CITED2 |
| 4.291e-02 | -3.15 | APICAL_PLASMA_MEMBRANE | MSigDB lists | APICAL_PLASMA_MEMBRANE | 14 | 4 | 17758 | 1761 |
ATP8B1,SHROOM2,SHROOM3,STX3 |
| 4.291e-02 | -3.15 | HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN | MSigDB lists | HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN | 14 | 4 | 17758 | 1761 |
RPL12,CDKN2D,S100A13,ATP13A2 |
| 4.291e-02 | -3.15 | DEAMINASE_ACTIVITY | MSigDB lists | DEAMINASE_ACTIVITY | 14 | 4 | 17758 | 1761 |
GNPDA1,CRYM,APOBEC3G,CDA |
| 4.291e-02 | -3.15 | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | 14 | 4 | 17758 | 1761 |
TM2D2,MAFF,FGF19,ESRP1 |
| 4.291e-02 | -3.15 | LIPID_HOMEOSTASIS | MSigDB lists | LIPID_HOMEOSTASIS | 14 | 4 | 17758 | 1761 |
NPC2,ABCA1,ABCG1,ABCA2 |
| 4.291e-02 | -3.15 | HUMMEL_BURKITTS_LYMPHOMA_DN | MSigDB lists | HUMMEL_BURKITTS_LYMPHOMA_DN | 14 | 4 | 17758 | 1761 |
MDFIC,CD40,S100A11,NFKBIA |
| 4.291e-02 | -3.15 | INSOLUBLE_FRACTION | MSigDB lists | INSOLUBLE_FRACTION | 14 | 4 | 17758 | 1761 |
TMBIM6,PDE4D,FAAH,TP53 |
| 4.291e-02 | -3.15 | NIKOLSKY_BREAST_CANCER_21Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_21Q22_AMPLICON | 14 | 4 | 17758 | 1761 |
COL18A1,COL6A2,PCBP3,COL6A1 |
| 4.291e-02 | -3.15 | STEINER_ERYTHROCYTE_MEMBRANE_GENES | MSigDB lists | STEINER_ERYTHROCYTE_MEMBRANE_GENES | 14 | 4 | 17758 | 1761 |
ADD3,ERMAP,ADD1,SPTB |
| 4.291e-02 | -3.15 | DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX | MSigDB lists | DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX | 14 | 4 | 17758 | 1761 |
SGCE,SNTB1,SGCB,SNTB2 |
| 4.291e-02 | -3.15 | PROTEIN_TRANSPORTER_ACTIVITY | MSigDB lists | PROTEIN_TRANSPORTER_ACTIVITY | 14 | 4 | 17758 | 1761 |
ZFYVE16,SEC61B,COG2,ABCG1 |
| 4.291e-02 | -3.15 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | 14 | 4 | 17758 | 1761 |
B4GALT4,MGAT4A,MGAT5,MGAT4B |
| 4.291e-02 | -3.15 | ZHANG_ADIPOGENESIS_BY_BMP7 | MSigDB lists | ZHANG_ADIPOGENESIS_BY_BMP7 | 14 | 4 | 17758 | 1761 |
SGK1,MAP3K5,AKT1,PIK3R1 |
| 4.291e-02 | -3.15 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | MSigDB lists | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | 14 | 4 | 17758 | 1761 |
PRKAA2,CAB39,STRADB,PRKAG2 |
| 4.292e-02 | -3.15 | CYCLIN | smart domains | SM00385 | 37 | 8 | 9131 | 997 |
CCNE2,CCNI,CCND1,RBL1,CCNJL,CCNB1,CCNF,CCNB2 |
| 4.297e-02 | -3.15 | regulation of dendritic spine morphogenesis | biological process | GO:0061001 | 26 | 6 | 16441 | 1675 |
ITPKA,PTEN,BHLHB9,SIPA1L1,EPHA4,CDK5R1 |
| 4.297e-02 | -3.15 | T cell mediated immunity | biological process | GO:0002456 | 26 | 6 | 16441 | 1675 |
BTN3A2,CD55,CTSC,EMP2,MICB,DLG1 |
| 4.297e-02 | -3.15 | membrane lipid catabolic process | biological process | GO:0046466 | 26 | 6 | 16441 | 1675 |
GLA,NAGA,GM2A,HEXB,SGPL1,CYP1B1 |
| 4.297e-02 | -3.15 | establishment of spindle orientation | biological process | GO:0051294 | 26 | 6 | 16441 | 1675 |
CENPA,GPSM2,NDE1,LLGL2,SPRY2,NDC80 |
| 4.303e-02 | -3.15 | LIPID_BINDING | MSigDB lists | LIPID_BINDING | 86 | 14 | 17758 | 1761 |
ZFYVE16,ARAP2,MCTP1,ARAP3,ALDH6A1,PGRMC1,BAX,ANXA9,NPC2,SYTL4,APOL2,RASGRP1,ACOT7,CCDC88A |
| 4.303e-02 | -3.15 | BIOCARTA_MAPK_PATHWAY | MSigDB lists | BIOCARTA_MAPK_PATHWAY | 86 | 14 | 17758 | 1761 |
MAP3K3,MAPKAPK2,RPS6KA2,RPS6KA1,RAPGEF2,NFKBIA,MAP3K9,TGFBR1,MAPK11,MAP3K5,ELK1,FOS,MAP3K6,MAPK12 |
| 4.303e-02 | -3.15 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | 86 | 14 | 17758 | 1761 |
IL17RB,GALNT3,APLP2,CA2,CDH1,ISM1,SNTB2,CYB5R2,LYPD6,ELF5,PTGER4,SORL1,HOOK1,NR3C2 |
| 4.303e-02 | -3.15 | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | 86 | 14 | 17758 | 1761 |
CCND1,RBL1,GCLC,CTDSPL,ENPP5,HEXB,DLG1,PTGER4,SERPINB6,AHCY,SLC1A3,RAB6A,NRP2,FAM69A |
| 4.303e-02 | -3.15 | POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 86 | 14 | 17758 | 1761 |
MAP3K3,RHOA,RIPK2,TSPAN6,PLK2,SECTM1,LITAF,NOD2,SLC44A2,CD40,F2R,TRAF5,NDFIP1,SLC20A1 |
| 4.303e-02 | -3.15 | GGCCAGT,MIR-193A,MIR-193B | MSigDB lists | GGCCAGT,MIR-193A,MIR-193B | 86 | 14 | 17758 | 1761 |
IRF2BPL,MAP3K3,LAMP2,PTPRF,CELSR2,PTEN,ZC3H11A,TMEM30A,DCAF7,FLRT3,FHDC1,SCYL3,CBX7,SIX4 |
| 4.303e-02 | -3.15 | chr1p35 | MSigDB lists | chr1p35 | 86 | 14 | 17758 | 1761 |
TMEM200B,AIM1L,TMEM54,MRPS15,PTPRU,FAAH,SERINC2,PDIK1L,TRIM62,IFI6,COL16A1,BSDC1,XKR8,PAQR7 |
| 4.305e-02 | -3.15 | Prostate Cancer | WikiPathways | WP2263 | 109 | 19 | 4455 | 516 |
PLK1,CASP3,AKT1,CASP9,TP53,ELK1,FOS,BARD1,CDK1,RHEB,RASA1,CCND1,JAK1,PTEN,PIK3CA,BAX,ETV4,GAB1,SPRY2 |
| 4.308e-02 | -3.14 | MAGEA4 (MAGE family member A4) | protein interactions | 4103 | 31 | 7 | 16036 | 1726 |
AMOTL2,PSMD10,MDM1,TRIM69,IQGAP1,BEX2,HLA-A |
| 4.308e-02 | -3.14 | TSC22D3 (TSC22 domain family, member 3) | protein interactions | 1831 | 31 | 7 | 16036 | 1726 |
SGK1,HDAC1,ALDH3B1,FOS,TSC22D3,HPCAL4,TP53 |
| 4.309e-02 | -3.14 | single-organism membrane organization | biological process | GO:0044802 | 786 | 95 | 16441 | 1675 |
SUN1,ATP8A1,TP53,PKP2,MPP5,F11R,BCL2L1,SYTL4,CCNB1,EMP2,SPTB,SYTL2,RAB15,CDH1,ZDHHC12,REEP1,DLG1,ZDHHC23,RPN2,SUN3,RAB20,DLG3,PACSIN1,LMAN1,ANO4,TRAM1,XKR8,ATG4D,PLK1,PPIF,SEC23A,KCNIP3,SEC61B,AKT1,SYNE2,EZR,ARFRP1,KIF13A,ATP1B1,RAB38,ICMT,MCFD2,CDK1,ATP10D,OPTN,DDOST,DNM1L,SYT13,REEP4,ABCA1,PACSIN2,TSPAN15,ATP9A,LRP4,ETV5,CTSZ,ANO9,CNTNAP2,LMNA,ZDHHC21,ATG4A,ADORA1,CTSC,PTEN,A4GALT,RPL39,KCNN4,CD9,BAX,ATP8B1,PLEKHF1,SYTL3,NUP85,PPP6R1,MYO5A,SUN2,RAB3B,PLSCR1,CRB3,RAPGEF2,ANO6,COL7A1,ATP8B3,BBS2,RPL12,FAT4,SERPINA1,SYT7,TMEM30A,ZDHHC7,SPCS3,ATP1B3,GPER1,CCNB2,NUP58 |
| 4.310e-02 | -3.14 | V$ALPHACP1_01 | MSigDB lists | V$ALPHACP1_01 | 245 | 33 | 17758 | 1761 |
SORT1,UGP2,DLGAP5,TSC22D3,SLC25A13,DNAJB11,CDH1,SHC3,CALD1,FLRT3,NEK2,SELK,GLB1L2,RP2,DLG3,SPRY2,CKS2,HES1,ASPM,PANK1,ELK1,LDB2,SLC25A4,PRCP,DBI,TLE1,AGFG2,FAM117A,ETAA1,NRGN,UBE2C,AFAP1,JARID2 |
| 4.313e-02 | -3.14 | Platelet calcium homeostasis | REACTOME pathways | R-HSA-418360 | 19 | 5 | 8202 | 867 |
ITPR2,ITPR3,STIM1,ITPR1,ATP2B1 |
| 4.313e-02 | -3.14 | MAP4 (microtubule associated protein 4) | protein interactions | 4134 | 58 | 11 | 16036 | 1726 |
SNTA1,LASP1,ENO2,LGR4,TRAF3IP1,PPP4R1,CSTF2,ERBB2IP,CCNB1,CDK1,SH3KBP1 |
| 4.316e-02 | -3.14 | Guanylate_kin | pfam domains | PF00625 | 26 | 6 | 16629 | 1696 |
MPP5,TJP3,DLG3,CACNB4,MPP1,DLG1 |
| 4.318e-02 | -3.14 | Androgen receptor signaling pathway | WikiPathways | WP138 | 88 | 16 | 4455 | 516 |
SIRT1,RHOA,RUNX2,BMF,AKT1,PIK3R1,ETV5,AES,PIAS3,CCND1,NCOA3,PTEN,HDAC1,ZMIZ1,NCOA2,NR2C2 |
| 4.318e-02 | -3.14 | Apoptotic execution phase | REACTOME pathways | R-HSA-75153 | 52 | 10 | 8202 | 867 |
CASP3,ADD1,CDH1,STK26,H1F0,DNM1L,PRKCQ,BCAP31,LMNA,OCLN |
| 4.320e-02 | -3.14 | TAPBP (TAP binding protein (tapasin)) | protein interactions | 6892 | 13 | 4 | 16036 | 1726 |
PDIA3,HLA-C,HLA-A,TAP1 |
| 4.320e-02 | -3.14 | LIFR (leukemia inhibitory factor receptor alpha) | protein interactions | 3977 | 13 | 4 | 16036 | 1726 |
PLCG1,FBXO6,IL6ST,IL31RA |
| 4.320e-02 | -3.14 | WDR45B (WD repeat domain 45B) | protein interactions | 56270 | 13 | 4 | 16036 | 1726 |
GAS2L1,AK4,RCN1,ARRDC1 |
| 4.320e-02 | -3.14 | SPTLC1 (serine palmitoyltransferase, long chain base subunit 1) | protein interactions | 10558 | 13 | 4 | 16036 | 1726 |
FBXO6,SPTLC2,ABCA1,RGS20 |
| 4.320e-02 | -3.14 | ITPR2 (inositol 1,4,5-trisphosphate receptor, type 2) | protein interactions | 3709 | 13 | 4 | 16036 | 1726 |
TRPC1,BANK1,PRKACA,CA8 |
| 4.320e-02 | -3.14 | BDKRB2 (bradykinin receptor B2) | protein interactions | 624 | 13 | 4 | 16036 | 1726 |
GRK6,ADRBK1,GNA11,ADRBK2 |
| 4.320e-02 | -3.14 | RNF128 (ring finger protein 128, E3 ubiquitin protein ligase) | protein interactions | 79589 | 13 | 4 | 16036 | 1726 |
RNF128,UBE2T,APPBP2,TP53 |
| 4.320e-02 | -3.14 | DLGAP3 (discs, large (Drosophila) homolog-associated protein 3) | protein interactions | 58512 | 13 | 4 | 16036 | 1726 |
DLGAP1,DLG3,CUL4B,DLG1 |
| 4.320e-02 | -3.14 | CAMKK1 (calcium/calmodulin-dependent protein kinase kinase 1, alpha) | protein interactions | 84254 | 13 | 4 | 16036 | 1726 |
SGK1,CAMK1D,AKT1,CALM1 |
| 4.320e-02 | -3.14 | PXDN (peroxidasin) | protein interactions | 7837 | 13 | 4 | 16036 | 1726 |
FBXO6,SCARA3,CNPY3,PLAUR |
| 4.320e-02 | -3.14 | C1orf186 (chromosome 1 open reading frame 186) | protein interactions | 440712 | 13 | 4 | 16036 | 1726 |
PLD1,PKN1,SBF1,FIGNL1 |
| 4.320e-02 | -3.14 | CERCAM (cerebral endothelial cell adhesion molecule) | protein interactions | 51148 | 13 | 4 | 16036 | 1726 |
GGH,FBXO6,KLK5,PLAUR |
| 4.320e-02 | -3.14 | LGMN (legumain) | protein interactions | 5641 | 13 | 4 | 16036 | 1726 |
FBXO6,LGMN,HNRNPH2,PDIA5 |
| 4.320e-02 | -3.14 | NEU2 (sialidase 2 (cytosolic sialidase)) | protein interactions | 4759 | 13 | 4 | 16036 | 1726 |
TFAP4,FAM217B,ZWINT,NOTCH3 |
| 4.320e-02 | -3.14 | VMA21 (VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)) | protein interactions | 203547 | 13 | 4 | 16036 | 1726 |
ECE1,PLIN3,PLAUR,TMEM9 |
| 4.324e-02 | -3.14 | MOHANKUMAR_TLX1_TARGETS_DN | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_DN | 168 | 24 | 17758 | 1761 |
RAB3B,HLA-F,GALNT12,FXYD3,EPHA4,C3orf52,IL18,GDF15,FAM198B,ALCAM,STEAP1,CA2,ARHGEF37,BMP7,NMI,STEAP2,SGK1,PLD1,UNC5B,GAD1,PKIA,S100A6,IGSF3,ARHGEF4 |
| 4.325e-02 | -3.14 | human chr4q22.1 | chromosome location | human chr4q22.1 | 19 | 4 | 26250 | 1887 |
ARHGAP24,HERC5,CCSER1,HERC6 |
| 4.325e-02 | -3.14 | human chr10q24.1 | chromosome location | human chr10q24.1 | 19 | 4 | 26250 | 1887 |
KIF11,PIK3AP1,TLL2,FAS |
| 4.325e-02 | -3.14 | human chr19q13 | chromosome location | human chr19q13 | 19 | 4 | 26250 | 1887 |
KLK10,USF2,PLAUR,KLC3 |
| 4.328e-02 | -3.14 | REACTOME_SIGNALING_BY_NOTCH | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH | 94 | 15 | 17758 | 1761 |
CCND1,HES1,TNRC6C,HDAC11,TP53,FURIN,DTX4,TLE1,ARRB1,HDAC1,NOTCH3,RAB6A,HDAC6,DNER,HDAC9 |
| 4.328e-02 | -3.14 | MODULE_128 | MSigDB lists | MODULE_128 | 94 | 15 | 17758 | 1761 |
TIMP2,TIMP3,TBC1D8B,CYR61,IFITM3,CD63,S100A4,DAPK1,KCTD12,FTH1,LGMN,BBS2,MAPK12,IER3,CYP1B1 |
| 4.328e-02 | -3.14 | Epstein-Barr virus infection | KEGG pathways | ko05169 | 199 | 30 | 6908 | 758 |
DDX58,NFKBIE,AKT1,HLA-E,HLA-F,PIK3R1,TP53,CR2,EIF2AK1,CD40,PRKACA,CDK1,HLA-A,HLA-B,PLCG1,PSMD1,JAK1,NFKBIA,PLCG2,PIK3CA,CDKN1B,HDAC1,MAPK11,HLA-C,PIK3CD,TRAF5,HSPB1,JAK3,SYK,MAPK12 |
| 4.328e-02 | -3.14 | Epstein-Barr virus infection | KEGG pathways | hsa05169 | 199 | 30 | 6908 | 758 |
DDX58,NFKBIE,AKT1,HLA-E,HLA-F,PIK3R1,TP53,CR2,EIF2AK1,CD40,PRKACA,CDK1,HLA-A,HLA-B,PLCG1,PSMD1,JAK1,NFKBIA,PLCG2,PIK3CA,CDKN1B,HDAC1,MAPK11,HLA-C,PIK3CD,TRAF5,HSPB1,JAK3,SYK,MAPK12 |
| 4.328e-02 | -3.14 | cAMP signaling pathway | KEGG pathways | ko04024 | 199 | 30 | 6908 | 758 |
MYL9,ARAP3,RHOA,AKT1,SOX9,CALM1,PIK3R1,PPARA,GRIN1,CALM3,ATP1B1,PRKACA,FOS,EDNRA,HTR1D,GNAS,CALM2,ATP1A1,ADORA1,NFKBIA,PIK3CA,GRIN2D,ATP1B3,PIK3CD,CACNA1D,PLD1,PDE4D,F2R,TIAM1,ATP2B1 |
| 4.328e-02 | -3.14 | cAMP signaling pathway | KEGG pathways | hsa04024 | 199 | 30 | 6908 | 758 |
MYL9,ARAP3,RHOA,AKT1,SOX9,CALM1,PIK3R1,PPARA,GRIN1,CALM3,ATP1B1,PRKACA,FOS,EDNRA,HTR1D,GNAS,CALM2,ATP1A1,ADORA1,NFKBIA,PIK3CA,GRIN2D,ATP1B3,PIK3CD,CACNA1D,PLD1,PDE4D,F2R,TIAM1,ATP2B1 |
| 4.344e-02 | -3.14 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | 185 | 26 | 17758 | 1761 |
UGP2,TNIP1,TRIP10,SLC1A3,OSR2,BCL2L1,RNF19B,STK17B,CMTM6,SIRPA,DCP2,NIN,SGPL1,PTPRJ,ITGB8,PIK3AP1,PVRL2,STK38,SLC2A6,FJX1,RAP2C,ARRB1,NFKBIZ,SERPINB1,KLF7,EHD1 |
| 4.344e-02 | -3.14 | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_UP | 185 | 26 | 17758 | 1761 |
MAP3K3,SIGIRR,SLC37A1,TSPAN15,FOXJ2,AMFR,CASP9,GNE,TAP1,DHX8,KIF1C,IL18,TEX2,NUF2,RAD17,SESN1,C3orf58,EPDR1,TMEM63A,ZDHHC12,TMEM51,ERAP1,IRF2,FAM117A,EIF4EBP2,FAIM |
| 4.344e-02 | -3.14 | GSE3982_EOSINOPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_UP | 185 | 26 | 17758 | 1761 |
ORAI2,MTM1,PRODH,REPS2,LGR4,ASAH1,FTH1,CAMK1D,SNN,SNTB1,CMTM6,TEAD3,HLA-B,SLC6A6,SWAP70,CYP1A1,LHX6,BCL6,FAM102A,SGK1,C2orf72,ZMIZ1,AHR,CKAP4,EGLN1,RRAGD |
| 4.350e-02 | -3.13 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular function | GO:0001228 | 317 | 42 | 16491 | 1673 |
RUNX2,GRHL2,EPAS1,SOX9,ETV5,TP53,PBX3,OSR2,SIX4,ELF3,TFAP4,HSF2,GRHL1,GATA2,MITF,ELF5,FOSB,TFAP2A,IRF2,MYBL1,ETV4,ELK3,PLSCR1,NR3C1,FOXJ2,NR4A1,NFE2L1,MYBL2,PPARA,TFAP2C,ELK1,FOS,NFIB,PITX2,NCOA3,ONECUT1,NR4A3,KLF5,NR4A2,HMGA1,MAFF,HOXC13 |
| 4.353e-02 | -3.13 | TGTATGA,MIR-485-3P | MSigDB lists | TGTATGA,MIR-485-3P | 143 | 21 | 17758 | 1761 |
SIRT1,ZMAT1,SYPL1,PPP4R4,RHOA,RUNX2,NR3C1,SOX9,C6orf106,ATP1B1,TRIB2,ZFAND5,MAPKAPK2,RNF220,CDK16,ANKS1B,TMEM30A,DAPK1,PIK3C2B,PDE4D,SNPH |
| 4.356e-02 | -3.13 | Pulmonary function(PMID:21946350) | GWAS genes | Pulmonary function(PMID:21946350) | 18 | 5 | 2389 | 269 |
MMP15,PPP1R14C,MICB,CCDC38,MECOM |
| 4.361e-02 | -3.13 | antigen receptor-mediated signaling pathway | biological process | GO:0050851 | 172 | 25 | 16441 | 1675 |
RIPK2,PSMB4,THEMIS2,INPP5D,PSME2,PIK3R1,BTN3A1,PSMD10,PSME1,PRKCQ,TEC,CACNB4,BCAR1,PSMA4,PLCG1,PTPRJ,PSMD1,PTEN,NFKBIA,PLCG2,BAX,PIK3CA,PIK3CD,PDE4D,SYK |
| 4.374e-02 | -3.13 | NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | 254 | 34 | 17758 | 1761 |
GLIS3,SIGIRR,RUNX2,NF2,S100A11,NKRF,CDKN2C,PAIP2B,FOSB,BCL6,ATP8B1,CDKN1B,IRF2,TWIST1,WWP1,CDKN2D,MDFI,SIRT1,TGIF1,ELK3,GCLC,DRAP1,CDA,FURIN,EIF2AK1,RAD17,ARHGAP35,MID1IP1,KLF12,TLE1,IRF7,KLF11,NRG1,GLA |
| 4.378e-02 | -3.13 | MULLIGHAN_MLL_SIGNATURE_1_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_DN | 228 | 31 | 17758 | 1761 |
CD99,BIN1,SERPINE2,STAT4,CTDSPL,C5orf30,PRKCQ,ISYNA1,YES1,ATP1B1,LHFPL2,HOXB2,TSPAN7,PGF,MDK,BTG3,TIMP3,HLF,JAK1,FUT2,SIPA1L1,ABCB1,DAPK1,FAM117A,CLMN,EGFL7,IFIT1,ITGAV,MAST4,ISOC1,FAH |
| 4.385e-02 | -3.13 | negative regulation of developmental growth | biological process | GO:0048640 | 84 | 14 | 16441 | 1675 |
GNAS,SEMA6B,PTEN,SEMA4D,NKD1,MAPK11,SEMA3G,WNT3A,SAV1,LGMN,SEMA3A,BBS2,CDK5R1,SEMA3B |
| 4.385e-02 | -3.13 | myelination | biological process | GO:0042552 | 84 | 14 | 16441 | 1675 |
CNTNAP1,MBP,UGT8,AKT1,PTEN,HEXB,CD9,ERBB2,KLK6,MPP5,SCN2A,PIKFYVE,DAG1,MYO5A |
| 4.385e-02 | -3.13 | metanephros development | biological process | GO:0001656 | 84 | 14 | 16441 | 1675 |
HES1,NKX3-1,LGR4,FMN1,BMP7,FRAS1,RET,SOX9,OSR2,GDF11,OSR1,SOX8,PDGFB,SIX4 |
| 4.388e-02 | -3.13 | L-lysine degradation II (L-pipecolate pathway) | BIOCYC pathways | META_PWY66-425 | 3 | 2 | 907 | 115 |
ALDH7A1,CRYM |
| 4.388e-02 | -3.13 | L-aspartate degradation II | BIOCYC pathways | META_MALATE-ASPARTATE-SHUTTLE-PWY | 3 | 2 | 907 | 115 |
GOT1,MDH1 |
| 4.388e-02 | -3.13 | putrescine degradation III | BIOCYC pathways | META_PWY-0 | 3 | 2 | 907 | 115 |
ALDH2,ALDH3A2 |
| 4.390e-02 | -3.13 | Sema4D mediated inhibition of cell attachment and migration | REACTOME pathways | R-HSA-416550 | 8 | 3 | 8202 | 867 |
RHOA,SEMA4D,ARHGAP35 |
| 4.390e-02 | -3.13 | Linoleic acid (LA) metabolism | REACTOME pathways | R-HSA-2046105 | 8 | 3 | 8202 | 867 |
FADS2,ABCD1,ELOVL3 |
| 4.391e-02 | -3.13 | metal ion homeostasis | biological process | GO:0055065 | 482 | 61 | 16441 | 1675 |
CCDC109B,EPAS1,CALB2,ATP2C2,HEXB,MTL5,ABCG2,SLC25A27,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,NEO1,ATP6V0B,APLP2,SCNN1A,GATA2,PLCG2,STEAP2,SGK3,BAX,SGK1,TRPC1,TMBIM6,CNNM4,TMEM64,SLC39A10,F2R,SLC12A2,ATP2B1,CD55,MFI2,ERO1A,GRIN1,ACO1,TTC7A,EIF2AK1,SLC11A2,ATP1B1,ITPR3,CD40,NUBP1,SFXN5,STEAP1,EDNRA,ATP13A2,FECH,SWAP70,ATP1A1,WFS1,ATP7B,ITPR1,INPP4B,GPER1,MCUR1,ATP1B3,NDFIP1,F2RL1,JAK3,CYBRD1 |
| 4.399e-02 | -3.12 | intrinsic component of the cytoplasmic side of the plasma membrane | cellular component | GO:0031235 | 14 | 4 | 17570 | 1756 |
DAB2IP,SPTB,RASA2,RASA1 |
| 4.399e-02 | -3.12 | other organism | cellular component | GO:0044215 | 14 | 4 | 17570 | 1756 |
IFIT1,LMAN1,AXL,TAP1 |
| 4.399e-02 | -3.12 | other organism cell | cellular component | GO:0044216 | 14 | 4 | 17570 | 1756 |
IFIT1,LMAN1,AXL,TAP1 |
| 4.399e-02 | -3.12 | other organism part | cellular component | GO:0044217 | 14 | 4 | 17570 | 1756 |
IFIT1,LMAN1,AXL,TAP1 |
| 4.399e-02 | -3.12 | compact myelin | cellular component | GO:0043218 | 14 | 4 | 17570 | 1756 |
AKR1B1,MPP5,MBP,PTEN |
| 4.403e-02 | -3.12 | ABC_transporter-like | interpro domains | IPR003439 | 48 | 9 | 18293 | 1814 |
ABCG2,ABCB1,TAP1,ABCA2,ABCD1,ABCA1,ABCG1,ABCC1,ABCD4 |
| 4.403e-02 | -3.12 | MARCHINI_TRABECTEDIN_RESISTANCE_DN | MSigDB lists | MARCHINI_TRABECTEDIN_RESISTANCE_DN | 48 | 9 | 17758 | 1761 |
MARCH8,HLA-B,BCAM,RND3,RUSC2,NOTCH3,CITED2,PKN1,SIRPA |
| 4.403e-02 | -3.12 | chr2p25 | MSigDB lists | chr2p25 | 48 | 9 | 17758 | 1761 |
TAF1B,PQLC3,GRHL1,CYS1,FAM110C,KLF11,CMPK2,TRIB2,PDIA6 |
| 4.415e-02 | -3.12 | REACTOME_GLUCOSE_METABOLISM | MSigDB lists | REACTOME_GLUCOSE_METABOLISM | 63 | 11 | 17758 | 1761 |
CALM2,PGM1,UGP2,ENO2,SLC25A13,CALM1,CALM3,GOT1,MDH1,PHKA2,PRKACA |
| 4.415e-02 | -3.12 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | 63 | 11 | 17758 | 1761 |
NUCB1,GAA,CLCN3,ELK3,TIMP3,NF2,HSPG2,CSF1,THRA,ATP7B,IRF2 |
| 4.415e-02 | -3.12 | PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | PROTEIN_TYROSINE_KINASE_ACTIVITY | 63 | 11 | 17758 | 1761 |
IGF1R,PTK7,AXL,NR4A3,RYK,ERBB2,ROR1,ERBB3,MERTK,DDR1,NRP2 |
| 4.420e-02 | -3.12 | cellular response to acid chemical | biological process | GO:0071229 | 164 | 24 | 16441 | 1675 |
PRKAA2,PDGFC,SHMT1,CPEB4,AKT1,FZD4,SOX9,RET,PDK3,BCL2L1,YES1,CCNB1,PDGFB,FZD7,GNAS,PTK7,COL6A1,SH3BP4,WNT3A,OSR1,COL16A1,RARG,ABCA1,RRAGD |
| 4.422e-02 | -3.12 | RGAGGAARY_V$PU1_Q6 | MSigDB lists | RGAGGAARY_V$PU1_Q6 | 477 | 59 | 17758 | 1761 |
PLA2G4A,IER5L,SEMA6B,CPEB4,POC1B,ARFGEF1,CCDC68,HMGN3,CAMK1D,ITPR2,PKN1,FAM81A,DPP8,PSIP1,IRF2BPL,TFAP4,CD109,ADD3,ADORA1,PIK3AP1,CYR61,NPNT,RINL,SLC16A6,VASN,ATP5H,ADAM15,TWIST1,RAB20,ACSL4,ERBB3,CACNA1D,CNOT6L,NCAM1,PLCB2,LAMP2,PRICKLE1,PPP1R14C,GLT8D2,ATP13A2,PITX2,PTPRJ,ACVRL1,SYT7,PTK7,CSF1,CORO1C,PRDM5,VSIG10,CTSA,ATP1B3,LEMD1,NDFIP1,ZNF502,NR3C2,AHR,ACOT7,ARHGEF4,PCSK5 |
| 4.430e-02 | -3.12 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 211 | 29 | 17758 | 1761 |
PGM1,CLCN3,ARAP2,SERPINE2,PQLC3,IFITM3,ST14,DDIT4L,TAP1,KBTBD11,PHLDA1,IER3,TFAP4,CPNE2,CTGF,WIPI1,PLOD2,PTK7,P4HA2,SIVA1,CGREF1,TMEM143,DAPK1,SP6,EGLN3,ZNF365,ETV4,DEF6,EGLN1 |
| 4.437e-02 | -3.12 | PENG_LEUCINE_DEPRIVATION_UP | MSigDB lists | PENG_LEUCINE_DEPRIVATION_UP | 135 | 20 | 17758 | 1761 |
ALDH2,ATP8A1,PCBP3,NFE2L1,MGST2,TRIB2,DCP2,H1FX,GPLD1,SWAP70,RIMS3,BMP7,AIM1,BMP1,ALPK3,SORL1,IRF2,USF2,APOBEC3G,TMEM131 |
| 4.440e-02 | -3.11 | phosphatidylinositol-3,4,5-trisphosphate binding | molecular function | GO:0005547 | 33 | 7 | 16491 | 1673 |
ZFYVE16,ARAP2,ARAP3,AKT1,NRGN,FAM21C,IQGAP1 |
| 4.443e-02 | -3.11 | SOLCAR | prosite domains | PS50920 | 53 | 10 | 11866 | 1235 |
SLC25A48,SLC25A24,SLC25A4,SLC25A13,SLC25A27,SLC25A30,SLC25A43,SLC25A5,SLC25A38,SLC25A36 |
| 4.444e-02 | -3.11 | peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | peripheral_T_cell_lymphoma_unspecified | 169 | 24 | 17775 | 1757 |
NCKAP5,RHOA,CPEB4,RUSC2,EPS8,TP53,KIF23,ITPR2,IDH1,S100A2,ADRBK2,SOX13,SOCS3,CDKN2C,PLCG1,PTEN,SLC9A6,TMEM30A,NKD1,PIK3CA,AKR1B1,LIMCH1,EPHB4,SYTL3 |
| 4.447e-02 | -3.11 | negative regulation of transcription, DNA-templated | biological process | GO:0045892 | 1162 | 136 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,ZFP36,SIVA1,MITF,FOSB,DLG1,IRF2,CRY2,ZBTB18,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,ITCH,CBX6,TFAP2C,EZR,LOXL2,AHRR,KLF12,PRDM5,NOD2,HDAC1,KLF11,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,TFAP4,IGF1R,GATA2,BHLHE41,MDFIC,PIM1,RFX5,ETV7,MDFI,ELK3,SALL4,NFIB,CDK5R1,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,RARG,EGLN1,FOXM1,THRA,TP53,OSR2,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,TWIST1,DAB2IP,NOTCH3,NR2C1,CHP1,SIRT1,DRAP1,ERBB2IP,H2AFV,NFIX,ARHGAP35,RBL1,WFS1,PEX2,OVOL1,TLE1,NRG1,IRF7,KLF5,CBX7,GLIS3,NKX3-1,DEPDC1,DAP,PSMD10,NKRF,AES,FZD6,SIX4,HDAC9,WWP2,FOXP2,IRF2BPL,CTNNBIP1,E2F7,TAF1B,BMP7,TFAP2A,TRIM21,TMBIM6,ATP8B1,WWP1,CITED2,NCOA2,NFE2L3,TGIF1,HES1,GCLC,PPARA,PRICKLE1,RUNX3,PITX2,NR1D2,FGFR2,TBX18,NR4A3,ARRB1,HMGA1,OSR1,SOX8,AHR,PKIA,ZBTB33,JARID2 |
| 4.449e-02 | -3.11 | IL6-mediated signaling events | Pathway Interaction DB | il6_7pathway | 43 | 11 | 2227 | 331 |
PIAS3,JAK1,AKT1,IL6ST,LMO4,PIK3R1,MITF,PIK3CA,MAPK11,FOS,SOCS3 |
| 4.449e-02 | -3.11 | MODULE_24 | MSigDB lists | MODULE_24 | 441 | 55 | 17758 | 1761 |
GCLM,BCAM,PCOLCE,HSPG2,EPAS1,BLVRB,PTTG1,CYB561,GDF15,BCL2L1,SEPP1,DHRS3,SDC1,CARD10,ARHGEF16,IER3,CCND1,CDH1,CYR61,LLGL2,COL6A1,TBCD,FUT1,GOT1,IGFBP2,IFIT1,ACSL4,PIM1,LGMN,CITED2,CKS2,FADS2,SHMT1,COL6A2,GCLC,MPP1,S100A4,CDC20,ACO1,AK4,TCF7,F12,CDK5R1,CYB5A,FUCA1,TIMP3,SERPINA1,AGPAT2,ETS2,ACADSB,PVRL2,ANXA9,UBE2C,JAK3,ABCA1 |
| 4.461e-02 | -3.11 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | 194 | 27 | 17758 | 1761 |
SEC23A,PGM1,NQO1,DNAJB2,PIP4K2C,LITAF,SPATA13,UBE2A,MORC4,NUSAP1,INTS8,IFIT3,SLC20A1,TYSND1,FZD6,CCND1,SWAP70,CTSC,SYT7,METTL7A,TIMM8A,FOSB,CD70,IRF7,SELK,NCOA2,DVL2 |
| 4.461e-02 | -3.11 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | 194 | 27 | 17758 | 1761 |
GRN,GCA,TRIM8,TIMP2,LGALS3,S100A11,RPS6KA1,S100A4,HEXB,ASAH1,EFHD2,KCTD12,ABR,GNS,ATP1A1,RBM47,SERPINA1,SEMA4D,SLC16A6,NOD2,PNPLA6,SGK1,SERPINB6,ZMIZ1,PTPRE,SLC27A3,CKAP4 |
| 4.461e-02 | -3.11 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | 194 | 27 | 17758 | 1761 |
B3GALT6,LAMP1,MBP,TNIP1,TESK1,CHCHD7,PSME2,USP18,STAT4,ARL4C,DIAPH2,SELL,SLC11A2,TCF7,NCKAP1,ITPR2,FAM101B,PDGFB,SESN1,TSEN34,ANKRD10,SIPA1L2,RPL39,IL6ST,ABCA2,TRAF5,PAQR7 |
| 4.461e-02 | -3.11 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | 194 | 27 | 17758 | 1761 |
TMEM68,TXN,PLSCR1,TBC1D1,FOXJ2,RC3H2,NFE2L1,EZR,MORF4L2,DSE,APPBP2,CDS1,CA2,SNX18,XYLT2,ITPR1,FAM114A1,PPP4R1,CABIN1,RFX5,MTMR11,ZDBF2,ALPK1,CACNA1D,PIKFYVE,ARMCX6,NRBP1 |
| 4.462e-02 | -3.11 | human chrXq11.1 | chromosome location | human chrXq11.1 | 5 | 2 | 26250 | 1887 |
SPIN4,ARHGEF9 |
| 4.462e-02 | -3.11 | human chr5q13.1 | chromosome location | human chr5q13.1 | 5 | 2 | 26250 | 1887 |
OCLN,PIK3R1 |
| 4.462e-02 | -3.11 | human chr5q12 | chromosome location | human chr5q12 | 5 | 2 | 26250 | 1887 |
PDE4D,CCNB1 |
| 4.464e-02 | -3.11 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | 177 | 25 | 17758 | 1761 |
BIN1,SUN2,LTBP1,RASGRF1,TBC1D8B,CHCHD7,HLA-F,TSC22D3,SYNE2,ERBB2,SLC35C1,SESN1,EDNRA,FAS,OPTN,PLCG1,ADD3,JAK1,TLE1,MAP3K5,NR3C2,CTDSP2,RASGRP1,CRTAP,WBP5 |
| 4.472e-02 | -3.11 | skull | COSMIC cancer mutations | skull | 27 | 6 | 17775 | 1757 |
GNAS,AKT1,IDH1,PTEN,PIK3CA,TP53 |
| 4.478e-02 | -3.11 | hippocampus development | biological process | GO:0021766 | 69 | 12 | 16441 | 1675 |
MDK,ANXA3,CASP3,NF2,PTEN,KIF14,PHLPP2,NR4A3,ZBTB18,WNT3A,BBS2,CDK5R1 |
| 4.478e-02 | -3.11 | microtubule bundle formation | biological process | GO:0001578 | 69 | 12 | 16441 | 1675 |
PLK1,GAS2L1,SPEF2,LRRC6,KIF20A,CAPN6,AK7,CFAP46,MAP2,BBS2,DNAAF3,CHP1 |
| 4.478e-02 | -3.11 | nephron morphogenesis | biological process | GO:0072028 | 69 | 12 | 16441 | 1675 |
CTNNBIP1,HES1,FAT4,LGR4,FMN1,NPNT,SOX9,DLG1,TACSTD2,OSR1,SOX8,ADAMTS16 |
| 4.478e-02 | -3.11 | positive regulation of phospholipase C activity | biological process | GO:0010863 | 69 | 12 | 16441 | 1675 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,EDNRA |
| 4.489e-02 | -3.10 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 642 | 77 | 17758 | 1761 |
SUN1,SIGIRR,SPRED1,AVPI1,FAM92A1,RET,TP53I11,SYTL4,ERP29,KREMEN1,DENND2D,NCS1,ZNF275,TTC21B,RGS3,OSBPL3,EPB41L4B,EGLN3,DLG3,SMYD5,CAMSAP3,RAB38,SESN1,DAG1,ARHGAP35,MAN2A2,ALDH5A1,KLF12,C19orf66,DNM1L,NGFRAP1,HOXA9,PNPLA6,PRDM5,ZNF704,DHTKD1,NFKBIZ,NRGN,RUNX2,ITGA6,UBASH3B,ISYNA1,HES2,LGALS3BP,FZD6,DNAJB9,PARM1,SLC25A36,IRF2BPL,ITGB8,PAIP2B,GATA2,LYPD6,FUT8,DAPK1,PLEKHF1,MAPK11,C8orf58,TLE6,KDELR1,ABCC1,C9orf9,FADS2,TGIF1,PDGFC,PGM1,CORO2A,NUB1,LRRC1,BCAR1,PRKAG2,ITPR1,PGRMC1,CLIP4,ZMIZ1,SNX30,DCBLD1 |
| 4.490e-02 | -3.10 | PX | prosite domains | PS50195 | 46 | 9 | 11866 | 1235 |
SNX18,SGK3,SNX16,PIK3C2B,PLD1,SNX10,SNX12,SNX30,SNX7 |
| 4.507e-02 | -3.10 | positive regulation of lymphocyte activation | biological process | GO:0051251 | 248 | 34 | 16441 | 1675 |
LAMP1,IL15,INPP5D,HLA-E,IL18,CD274,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,PIK3CA,IGFBP2,WNT3A,SLC39A10,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,AKT1,RIPK2,PIK3R1,PRKCQ,YES1,CD40,CD83,IRS2,AXL,NOD2,PPP2R3C,ICOSLG,JAK3 |
| 4.513e-02 | -3.10 | GAL_LEUKEMIC_STEM_CELL_UP | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_UP | 127 | 19 | 17758 | 1761 |
BIN1,NF2,HJURP,CPT2,FBXO9,CTSZ,COL7A1,B4GALT4,HDAC6,ETS1,CCND1,IGF1R,COL6A1,AGFG2,ANXA9,UNC5B,DLG3,ALS2CL,MPHOSPH9 |
| 4.513e-02 | -3.10 | ACTIN_CYTOSKELETON | MSigDB lists | ACTIN_CYTOSKELETON | 127 | 19 | 17758 | 1761 |
MYL9,BIN1,LASP1,BMF,SORBS1,IQGAP1,EZR,ANLN,AIF1L,SPTB,DAG1,KLHL2,CDH1,CORO1C,DAPK1,ESPN,ARPC2,SHROOM2,NEB |
| 4.513e-02 | -3.10 | TPR-contain_dom | interpro domains | IPR013026 | 127 | 19 | 18293 | 1814 |
TTC8,TMTC1,LONRF3,CEP70,DNAJC3,TTC7A,EMC2,GPSM2,IFIT3,NPHP3,AIP,APPBP2,TTC21B,TRANK1,P4HA2,KLC3,CABIN1,IFIT1,TANC2 |
| 4.524e-02 | -3.10 | regulation of NF-kappaB import into nucleus | biological process | GO:0042345 | 47 | 9 | 16441 | 1675 |
NOV,RHOA,BMP7,NFKBIA,LITAF,PSMD10,PRKCQ,IL18,IL18R1 |
| 4.524e-02 | -3.10 | tissue regeneration | biological process | GO:0042246 | 47 | 9 | 16441 | 1675 |
NOV,TIMP3,BCL9,ADAM15,KLK6,PRKCQ,TEC,CCNB1,FZD7 |
| 4.524e-02 | -3.10 | positive regulation of actin filament bundle assembly | biological process | GO:0032233 | 47 | 9 | 16441 | 1675 |
RHOA,SWAP70,NF2,CTGF,LIMK1,SDC4,RGCC,PRKCQ,EPHA1 |
| 4.524e-02 | -3.10 | endothelial cell development | biological process | GO:0001885 | 47 | 9 | 16441 | 1675 |
RAPGEF2,RAP2C,EZR,COL18A1,F11R,PDE4D,PLOD3,F2RL1,ARHGEF26 |
| 4.524e-02 | -3.10 | regulation of mitotic sister chromatid separation | biological process | GO:0010965 | 47 | 9 | 16441 | 1675 |
PLK1,DLGAP5,PTEN,CIT,PTTG1,CDC20,BUB1,UBE2C,ESPL1 |
| 4.524e-02 | -3.10 | positive regulation of phagocytosis | biological process | GO:0050766 | 47 | 9 | 16441 | 1675 |
GATA2,ANO6,NOD2,ITGAV,CAMK1D,F2RL1,MERTK,RAP1GAP,ABR |
| 4.527e-02 | -3.10 | negative regulation of B cell activation | biological process | GO:0050869 | 33 | 7 | 16441 | 1675 |
CASP3,BANK1,PKN1,NDFIP1,INPP5D,FAS,BCL6 |
| 4.527e-02 | -3.10 | sodium ion homeostasis | biological process | GO:0055078 | 33 | 7 | 16441 | 1675 |
SGK1,ATP1B1,ATP1A1,ATP1B3,SCNN1A,SLC12A2,SGK3 |
| 4.529e-02 | -3.09 | blood circulation | biological process | GO:0008015 | 308 | 41 | 16441 | 1675 |
GAA,SCN5A,GCLM,F11R,CTSZ,PDGFB,EMP2,HOXB2,HTR1D,IER3,CTNNBIP1,RPS6KA2,ADORA1,ADRBK1,PRKG1,PIK3CA,SGK1,ECE1,PDE4D,F2R,ERAP2,GCLC,PPARA,YES1,ATP1B1,RNPEP,BBS2,ABR,EDNRA,ARHGAP35,ATP1A1,PTPRJ,ACVRL1,DNM1L,PRCP,ERAP1,STK39,PLOD3,F2RL1,ADAMTS16,PCSK5 |
| 4.529e-02 | -3.09 | Wnt signaling network | Pathway Interaction DB | wnt_signaling_pathway | 28 | 8 | 2227 | 331 |
CTHRC1,FZD4,RYK,WNT3A,FZD5,KREMEN1,FZD7,FZD6 |
| 4.531e-02 | -3.09 | DLD (dihydrolipoamide dehydrogenase) | protein interactions | 1738 | 80 | 14 | 16036 | 1726 |
SLC2A4,HNRNPH2,PCBP3,OGDHL,SORL1,DHTKD1,GGH,ISYNA1,PDK3,ATP1B1,ATP1B3,MRPS36,SNX12,CTH |
| 4.532e-02 | -3.09 | S100_Ca-bd_sub | interpro domains | IPR013787 | 27 | 6 | 18293 | 1814 |
S100A11,S100A2,S100A4,S100A13,S100A6,S100A5 |
| 4.533e-02 | -3.09 | GNF2_CASP8 | MSigDB lists | GNF2_CASP8 | 27 | 6 | 17758 | 1761 |
BTN3A2,DDX58,BTN3A1,HECA,SEMA4D,STK38 |
| 4.533e-02 | -3.09 | GENTILE_UV_LOW_DOSE_UP | MSigDB lists | GENTILE_UV_LOW_DOSE_UP | 27 | 6 | 17758 | 1761 |
GDF15,PLK2,TOB1,EFNB1,SAT1,TAP1 |
| 4.533e-02 | -3.09 | OLSSON_E2F3_TARGETS_UP | MSigDB lists | OLSSON_E2F3_TARGETS_UP | 27 | 6 | 17758 | 1761 |
FAM102A,ECE1,FAM46A,TMPRSS4,DAG1,ELF3 |
| 4.533e-02 | -3.09 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | MSigDB lists | ST_GRANULE_CELL_SURVIVAL_PATHWAY | 27 | 6 | 17758 | 1761 |
ASAH1,CASP3,ITPKA,FOS,DAG1,MAPK8IP1 |
| 4.533e-02 | -3.09 | LIPID_TRANSPORTER_ACTIVITY | MSigDB lists | LIPID_TRANSPORTER_ACTIVITY | 27 | 6 | 17758 | 1761 |
ATP8B1,PITPNA,PLSCR1,PCTP,ABCA1,ABCG1 |
| 4.533e-02 | -3.09 | GNF2_LYN | MSigDB lists | GNF2_LYN | 27 | 6 | 17758 | 1761 |
SELL,LTA4H,ERP29,CNPY3,SYK,CMTM6 |
| 4.533e-02 | -3.09 | KEGG_O_GLYCAN_BIOSYNTHESIS | MSigDB lists | KEGG_O_GLYCAN_BIOSYNTHESIS | 27 | 6 | 17758 | 1761 |
C1GALT1C1,GALNT3,GALNT7,ST3GAL1,GALNT12,GCNT1 |
| 4.533e-02 | -3.09 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | MSigDB lists | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | 27 | 6 | 17758 | 1761 |
CDKN1B,PHLPP1,AKT1,PTEN,NR4A1,CASP9 |
| 4.533e-02 | -3.09 | BOYAULT_LIVER_CANCER_SUBCLASS_G2 | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G2 | 27 | 6 | 17758 | 1761 |
RPN2,MCTP1,EPHA1,ARHGEF40,KIF14,SLC2A6 |
| 4.533e-02 | -3.09 | BIOCARTA_CREB_PATHWAY | MSigDB lists | BIOCARTA_CREB_PATHWAY | 27 | 6 | 17758 | 1761 |
GNAS,PRKAR2B,AKT1,RPS6KA1,PIK3R1,PIK3CA |
| 4.537e-02 | -3.09 | Tight junction | KEGG pathways | ko04530 | 138 | 22 | 6908 | 758 |
MYL9,RHOA,RAB3B,AKT1,CRB3,MRAS,F11R,MPP5,PRKCQ,YES1,MYL12A,TJP3,LLGL2,SHROOM3,PTEN,CLDN4,MYH14,CTTN,SHROOM2,PPP2R2D,MYL12B,OCLN |
| 4.537e-02 | -3.09 | Tight junction | KEGG pathways | hsa04530 | 138 | 22 | 6908 | 758 |
MYL9,RHOA,RAB3B,AKT1,CRB3,MRAS,F11R,MPP5,PRKCQ,YES1,MYL12A,TJP3,LLGL2,SHROOM3,PTEN,CLDN4,MYH14,CTTN,SHROOM2,PPP2R2D,MYL12B,OCLN |
| 4.537e-02 | -3.09 | ATGTTTC,MIR-494 | MSigDB lists | ATGTTTC,MIR-494 | 152 | 22 | 17758 | 1761 |
TGIF1,PCOLCE,MMD,NF2,TACC1,FOXJ2,SYNE2,ELOVL3,EIF5A2,GALNT7,MORF4L2,SP4,DPYSL3,PITX2,IRF2BPL,ANKS1B,FGFR2,WDR44,ZNRF2,PTER,FUT8,MYLIP |
| 4.542e-02 | -3.09 | Signaling events regulated by Ret tyrosine kinase | Pathway Interaction DB | ret_pathway | 38 | 10 | 2227 | 331 |
IRS2,RHOA,DOK4,PIK3R1,RET,PIK3CA,BCAR1,PRKACA,GAB1,RASA1 |
| 4.542e-02 | -3.09 | peptidase activator activity involved in apoptotic process | molecular function | GO:0016505 | 20 | 5 | 16491 | 1673 |
CDKN1B,CARD8,NKX3-1,CTSC,NGFRAP1 |
| 4.542e-02 | -3.09 | ankyrin binding | molecular function | GO:0030506 | 20 | 5 | 16491 | 1673 |
SCN5A,ATP1A1,CACNA1D,CDH1,SPTB |
| 4.542e-02 | -3.09 | histone kinase activity | molecular function | GO:0035173 | 20 | 5 | 16491 | 1673 |
PRKAA2,AURKA,PKN1,CCNB1,CDK1 |
| 4.542e-02 | -3.09 | phosphatidylinositol bisphosphate phosphatase activity | molecular function | GO:0034593 | 20 | 5 | 16491 | 1673 |
MTM1,PIKFYVE,PTEN,TMEM55B,INPP4B |
| 4.543e-02 | -3.09 | negative regulation of nitrogen compound metabolic process | biological process | GO:0051172 | 1487 | 171 | 16441 | 1675 |
SIGIRR,TXN,LGR4,CRYM,TSC22D3,LMCD1,MORF4L2,HDAC6,PDGFB,BARD1,ZFP36,SIVA1,MITF,FOSB,DLG1,IRF2,CRY2,ZBTB18,APOBEC3G,CYP1B1,PLK1,THRB,SMARCA2,KCNIP3,TRIM8,ITCH,CDA,CBX6,TFAP2C,EZR,AGO4,LOXL2,PIF1,EDNRA,AHRR,NEIL1,KLF12,PRDM5,NOD2,HDAC1,EIF4EBP2,KLF11,GLA,E2F8,RUNX2,CDKN1C,SOX9,HES2,MECOM,ELF3,TFAP4,IGF1R,PAIP2B,GATA2,BHLHE41,DAPK1,SORL1,MDFIC,RFX5,PIM1,ETV7,MDFI,ELK3,SALL4,EIF2AK1,NFIB,CDK5R1,NUDT16,ETS2,SEMA4D,NFKBIA,NLRC5,SFMBT1,NR4A2,PER3,TOB1,RARG,EGLN1,NF2,S100A11,FOXM1,THRA,TP53,OSR2,IER3,CCND1,SETDB2,SP100,DACT1,BCL6,CDKN1B,DAB2IP,TWIST1,NOTCH3,NR2C1,CHP1,SIRT1,PPIF,APOBEC3D,DRAP1,ERBB2IP,RAD17,H2AFV,ARHGAP35,NFIX,RBL1,WFS1,PEX2,PTBP3,OVOL1,TLE1,NRG1,IRF7,KLF5,CBX7,GLIS3,NKX3-1,TNRC6C,DEPDC1,CPEB4,DAP,PSMD10,NKRF,APOBEC3H,AES,SIX4,FZD6,HDAC9,WWP2,CTNNBIP1,IRF2BPL,FOXP2,E2F7,TAF1B,BMP7,TFAP2A,ATP8B1,TRIM21,TMBIM6,WWP1,CITED2,CNOT6L,TRIM62,NCOA2,NFE2L3,TGIF1,HES1,RHOA,IFITM3,GCLC,PPARA,PRICKLE1,RUNX3,PITX2,BANK1,FGFR2,ACVRL1,NR1D2,TBX18,NR4A3,ARRB1,HMGA1,GPER1,OSR1,SOX8,NDFIP1,CPEB2,AHR,PKIA,ZBTB33,JARID2 |
| 4.546e-02 | -3.09 | SH2B2 (SH2B adaptor protein 2) | protein interactions | 10603 | 25 | 6 | 16036 | 1726 |
ERBB2,SORBS1,JAK1,AKT1,JAK3,SYK |
| 4.546e-02 | -3.09 | SNTB2 (syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)) | protein interactions | 6645 | 25 | 6 | 16036 | 1726 |
KCNJ12,SCN5A,SAV1,SNTB2,ABCA1,UTRN |
| 4.546e-02 | -3.09 | CD19 (CD19 molecule) | protein interactions | 930 | 25 | 6 | 16036 | 1726 |
CR2,SYK,CD82,PLCG2,PIK3R1,CD9 |
| 4.546e-02 | -3.09 | HEY2 (hes-related family bHLH transcription factor with YRPW motif 2) | protein interactions | 23493 | 25 | 6 | 16036 | 1726 |
HDAC1,SIRT1,CASP3,HES1,PLSCR1,HDAC9 |
| 4.546e-02 | -3.09 | FLT1 (fms-related tyrosine kinase 1) | protein interactions | 2321 | 25 | 6 | 16036 | 1726 |
PGF,PLCG1,YES1,PLCG2,NRP2,PIK3R1 |
| 4.546e-02 | -3.09 | FRS3 (fibroblast growth factor receptor substrate 3) | protein interactions | 10817 | 25 | 6 | 16036 | 1726 |
ERBB2,AES,PLSCR1,ADAMTSL4,SPRY2,SH3KBP1 |
| 4.546e-02 | -3.09 | CARHSP1 (calcium regulated heat stable protein 1) | protein interactions | 23589 | 25 | 6 | 16036 | 1726 |
SGK1,PIAS3,DAZAP1,AKT1,HSPB1,RPS6KA1 |
| 4.546e-02 | -3.09 | HMOX1 (heme oxygenase 1) | protein interactions | 3162 | 25 | 6 | 16036 | 1726 |
NRG1,HLA-C,UGT8,AKT1,POR,BLVRB |
| 4.546e-02 | -3.09 | ARNTL (aryl hydrocarbon receptor nuclear translocator-like) | protein interactions | 406 | 25 | 6 | 16036 | 1726 |
SIRT1,CRY2,HLF,PER3,EPAS1,AHR |
| 4.546e-02 | -3.09 | ADAM10 (ADAM metallopeptidase domain 10) | protein interactions | 102 | 25 | 6 | 16036 | 1726 |
PDIA3,B3GNT2,FBXO6,TSPAN15,AXL,DLG1 |
| 4.546e-02 | -3.09 | ciliary basal body | cellular component | GO:0036064 | 86 | 14 | 17570 | 1756 |
TTC8,PIFO,LCA5,AKT1,POC1B,TRAF3IP1,CCSAP,TUBG1,EZR,RP2,CFAP20,CEP41,BBS2,DZIP1L |
| 4.549e-02 | -3.09 | negative regulation of inflammatory response | biological process | GO:0050728 | 100 | 16 | 16441 | 1675 |
PSMB4,NLRX1,PBK,PTGER4,PPARA,ETS1,GSTP1,ABR,IER3,SOCS3,NOV,ADORA1,NOD2,DUSP10,GPER1,NDFIP1 |
| 4.550e-02 | -3.09 | hexose metabolic process | biological process | GO:0019318 | 181 | 26 | 16441 | 1675 |
MAN2B2,PGM1,GAA,ENO2,UGP2,AKT1,SLC25A13,CALM1,CALM3,PDK3,PRKACA,IRS2,CALM2,FUCA1,MAN2A2,ONECUT1,ALDH5A1,FUT2,FUT8,FUT1,PIK3CA,AKR1B1,PGM2L1,MDH1,GOT1,PHKA2 |
| 4.553e-02 | -3.09 | REGULATION_OF_MITOSIS | MSigDB lists | REGULATION_OF_MITOSIS | 41 | 8 | 17758 | 1761 |
ZWINT,NEK2,NUSAP1,BUB1,RAD17,PKMYT1,ANLN,UBE2C |
| 4.553e-02 | -3.09 | KEGG_LYSINE_DEGRADATION | MSigDB lists | KEGG_LYSINE_DEGRADATION | 41 | 8 | 17758 | 1761 |
ALDH2,SETDB2,AASS,PLOD2,OGDHL,ALDH7A1,PLOD3,ALDH3A2 |
| 4.553e-02 | -3.09 | ZHAN_MULTIPLE_MYELOMA_LB_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_UP | 41 | 8 | 17758 | 1761 |
PCGF5,CGREF1,CTTN,RELL1,PLXNA1,MAST4,CYBRD1,RASGRP1 |
| 4.553e-02 | -3.09 | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | 41 | 8 | 17758 | 1761 |
NFE2L3,SLC44A1,DDR1,NR2C1,CDK1,CYB5A,NFIX,FAS |
| 4.553e-02 | -3.09 | KEGG_BLADDER_CANCER | MSigDB lists | KEGG_BLADDER_CANCER | 41 | 8 | 17758 | 1761 |
CCND1,PGF,DAPK2,TYMP,CDH1,DAPK1,TP53,ERBB2 |
| 4.554e-02 | -3.09 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 71 | 12 | 17758 | 1761 |
CPD,NR1D2,EPS8,AOX1,GEM,NCAM1,TMEM159,SESN1,LIFR,CASP4,ABCA1,GABARAPL1 |
| 4.554e-02 | -3.09 | BURTON_ADIPOGENESIS_2 | MSigDB lists | BURTON_ADIPOGENESIS_2 | 71 | 12 | 17758 | 1761 |
SLC6A6,AVPI1,NF2,KCNN4,GNPTAB,LIMK1,TLE1,ST3GAL1,SDC1,MAP3K6,PTGES,XDH |
| 4.554e-02 | -3.09 | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | MSigDB lists | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | 71 | 12 | 17758 | 1761 |
MFAP3L,SPEF2,MLPH,PLCG2,MATN2,TWIST1,CABIN1,RUNX3,CD274,PTGES,ZNF275,CD33 |
| 4.555e-02 | -3.09 | G1 to S cell cycle control | WikiPathways | WP45 | 68 | 13 | 4455 | 516 |
CCND1,CCNE2,CDKN2C,WEE1,CDKN1C,RBL1,TP53,CDKN1B,CCNB1,CDKN2D,MYT1,CDK1,PRIM1 |
| 4.570e-02 | -3.09 | ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN | 352 | 45 | 17758 | 1761 |
IER5L,AVPI1,ARAP3,FRMD4A,ZNF395,CNOT8,NDRG2,INTS8,SLC20A1,SDC1,ARHGEF40,CDS1,HDAC9,SLC25A36,C7orf49,SETDB2,SNX18,TBCD,ECI2,SGK1,TACSTD2,C10orf54,ARMCX6,SPRY2,MBP,MFI2,PIK3R1,PDE5A,RNF113A,MCFD2,FOS,FANCE,DAG1,STEAP1,FAM64A,KLF12,PLK2,OTUB2,RHOBTB2,NRG1,HOXB13,FHL1,F2RL1,SLC25A30,TOB1 |
| 4.573e-02 | -3.09 | synaptic membrane | cellular component | GO:0097060 | 253 | 34 | 17570 | 1756 |
LRP4,EPHA4,GABRG2,ERBB2,KCTD12,PJA2,SRPX2,NCS1,SNTA1,ADORA1,ITGA3,PTEN,ANKS1B,ZNRF2,CABP1,FLRT3,DLG1,DLG3,F2R,RIMS2,DLGAP1,UTRN,GRIN1,SCRIB,DAG1,GABRD,SIPA1L1,ARRB1,GRIN2D,GPER1,RGS14,L1CAM,LZTS1,RUSC1 |
| 4.579e-02 | -3.08 | N-cadherin signaling events | Pathway Interaction DB | ncadherinpathway | 33 | 9 | 2227 | 331 |
KIF5B,CALM2,PLCG1,RHOA,CALM1,PIK3R1,PIK3CA,CALM3,CTTN |
| 4.579e-02 | -3.08 | long-chain fatty acid transport | biological process | GO:0015909 | 40 | 8 | 16441 | 1675 |
PLA2G4A,PRKAA2,ACACB,PRKAG2,SLC27A6,CPT2,ABCD1,SLC27A1 |
| 4.579e-02 | -3.08 | regulation of substrate adhesion-dependent cell spreading | biological process | GO:1900024 | 40 | 8 | 16441 | 1675 |
AP1AR,MFI2,CORO1C,TRIOBP,TACSTD2,ARPC2,FAM21C,FBLN1 |
| 4.579e-02 | -3.08 | positive regulation of kidney development | biological process | GO:0090184 | 40 | 8 | 16441 | 1675 |
PDGFA,HOXB7,LGR4,SOX9,RET,SOX8,PDGFB,SIX4 |
| 4.584e-02 | -3.08 | V$NFKB_C | MSigDB lists | V$NFKB_C | 255 | 34 | 17758 | 1761 |
LASP1,BMF,LRRFIP2,NDRG2,IL27RA,NOTUM,BCL2L1,TRIB2,DDR1,IL18R1,SPTB,CTGF,ITGB8,AKR1B1,CD70,TINAGL1,SEMA3B,SUN2,RHOA,TNIP1,FOXJ2,CD40,FOS,CYB5A,FOXD2,PTPRJ,RAP2C,NFKBIA,UACA,FAM117A,SP6,GRIN2D,JAK3,PTGES |
| 4.588e-02 | -3.08 | SH2 | pfam domains | PF00017 | 100 | 16 | 16629 | 1696 |
INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,BCAR3,PLCG1,TNS3,SHC3,PLCG2,SYK,SOCS5 |
| 4.589e-02 | -3.08 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | 221 | 30 | 17775 | 1757 |
ZNF462,MX1,ARHGEF3,ATP9A,CUL4B,PIK3R1,TP53,CNTNAP2,PM20D2,IDH1,DOCK5,PRRG4,FAS,DIRAS3,UBE2Q2,PTEN,ISM1,TMEM30A,BMP7,NFKBIA,FAM102A,CLMN,ARRDC1,PIM1,FAIM,SNX10,TBC1D4,SYK,ABCA1,RIMS2 |
| 4.589e-02 | -3.08 | regulation of actin polymerization or depolymerization | biological process | GO:0008064 | 132 | 20 | 16441 | 1675 |
SSH3,RHOA,SSH1,ADD1,FMN1,EPS8,ARFGEF1,SPTB,RASA1,PLEKHH2,SWAP70,DLG1,TRIOBP,SPTBN5,TMOD2,CTTN,ARPC2,ARF6,SHROOM2,F2RL1 |
| 4.592e-02 | -3.08 | CYCLIN_D1_KE_.V1_UP | MSigDB lists | CYCLIN_D1_KE_.V1_UP | 186 | 26 | 17758 | 1761 |
CASP3,HSPG2,DAP,BCL9,DCAF7,RASSF7,COL18A1,KLK6,DUSP4,PKN1,KCTD2,S100A2,CDS1,MMP15,MAN2A2,ETS2,RGS3,CGREF1,TFAP2A,GOT1,NRG1,FZD5,PLCB2,ALDH3A2,MGAT5,AHR |
| 4.592e-02 | -3.08 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_UP | 186 | 26 | 17758 | 1761 |
RMND5A,PRODH,ING1,ERLEC1,AVPI1,ALDH2,MOSPD2,RPS6KA1,PCBP3,ITCH,SLC35C1,COL4A5,GGH,TMEM63A,PLS3,ADD3,IMPAD1,BMP7,SLC44A1,SLC44A2,TSPAN13,LIMCH1,OSR1,RAB27B,PTPRE,EHD1 |
| 4.592e-02 | -3.08 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | 186 | 26 | 17758 | 1761 |
SUSD3,GLIS3,TNIP1,RUSC2,USP18,BLVRB,COL7A1,ATP8B3,IFIT3,CD40,ITPR3,ATP10D,TTYH3,BSDC1,SYTL2,GABRD,COQ10A,FOSB,ANKRD12,FAM102A,CMPK2,ARSB,TRAF5,ST3GAL1,SLC16A5,PAQR7 |
| 4.592e-02 | -3.08 | GSE3982_MAST_CELL_VS_TH2_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_UP | 186 | 26 | 17758 | 1761 |
RMND5A,CLCN3,SORBS1,LPGAT1,CAST,ZCCHC24,CCDC68,ASAH1,NDRG2,BLVRA,MCFD2,ZFYVE9,DNAJB9,RHEB,GALNT3,GNS,TIMP3,COL13A1,TSPAN6,PAPSS1,DUSP10,ZDHHC7,RP2,SPRY2,CRTAP,SOCS5 |
| 4.599e-02 | -3.08 | positive regulation of leukocyte activation | biological process | GO:0002696 | 274 | 37 | 16441 | 1675 |
LAMP1,IL15,INPP5D,HLA-E,IL18,CD274,TNFSF9,EFNB1,HLA-A,IL6ST,BCL6,PIK3CA,IGFBP2,WNT3A,SLC39A10,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,AKT1,RIPK2,PIK3R1,PRKCQ,YES1,CD40,CD83,IRS2,PVRL2,AXL,NR4A3,NOD2,PPP2R3C,ICOSLG,JAK3,F2RL1 |
| 4.604e-02 | -3.08 | PCYT1A (phosphate cytidylyltransferase 1, choline, alpha) | protein interactions | 5130 | 8 | 3 | 16036 | 1726 |
PDIA6,BARD1,S100A13 |
| 4.604e-02 | -3.08 | KIAA0391 (KIAA0391) | protein interactions | 9692 | 8 | 3 | 16036 | 1726 |
RP2,F12,PLAUR |
| 4.604e-02 | -3.08 | CREG1 (cellular repressor of E1A-stimulated genes 1) | protein interactions | 8804 | 8 | 3 | 16036 | 1726 |
FBXO6,RBL1,CAPN1 |
| 4.604e-02 | -3.08 | GAS6 (growth arrest-specific 6) | protein interactions | 2621 | 8 | 3 | 16036 | 1726 |
MERTK,HLA-E,AXL |
| 4.604e-02 | -3.08 | NDST2 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2) | protein interactions | 8509 | 8 | 3 | 16036 | 1726 |
RCN1,HLA-E,PLAUR |
| 4.604e-02 | -3.08 | Casc5 (cancer susceptibility candidate 5) | protein interactions | 76464 | 8 | 3 | 16036 | 1726 |
NUF2,ZWINT,NDC80 |
| 4.604e-02 | -3.08 | ABCG8 (ATP binding cassette subfamily G member 8) | protein interactions | 64241 | 8 | 3 | 16036 | 1726 |
MAL2,AGPAT2,NR4A1 |
| 4.604e-02 | -3.08 | Melk (maternal embryonic leucine zipper kinase) | protein interactions | 17279 | 8 | 3 | 16036 | 1726 |
TXN,MAP3K5,TP53 |
| 4.604e-02 | -3.08 | MPP2 (membrane protein, palmitoylated 2) | protein interactions | 4355 | 8 | 3 | 16036 | 1726 |
PLK1,ERBB2IP,DLG1 |
| 4.604e-02 | -3.08 | RHOH (ras homolog family member H) | protein interactions | 399 | 8 | 3 | 16036 | 1726 |
ARHGDIB,TGFBR1,LRIF1 |
| 4.604e-02 | -3.08 | TSPAN4 (tetraspanin 4) | protein interactions | 7106 | 8 | 3 | 16036 | 1726 |
ITGA3,ITGA6,CD9 |
| 4.604e-02 | -3.08 | STK17B (serine/threonine kinase 17b) | protein interactions | 9262 | 8 | 3 | 16036 | 1726 |
STK17B,TMEM30A,CHP1 |
| 4.604e-02 | -3.08 | SCHIP1 (schwannomin interacting protein 1) | protein interactions | 29970 | 8 | 3 | 16036 | 1726 |
SCOC,NF2,FOS |
| 4.604e-02 | -3.08 | DGKQ (diacylglycerol kinase theta) | protein interactions | 1609 | 8 | 3 | 16036 | 1726 |
EZR,RHOA,EHD1 |
| 4.604e-02 | -3.08 | ITM2C (integral membrane protein 2C) | protein interactions | 81618 | 8 | 3 | 16036 | 1726 |
MVB12B,FURIN,RYK |
| 4.604e-02 | -3.08 | MAP3K6 (mitogen-activated protein kinase kinase kinase 6) | protein interactions | 9064 | 8 | 3 | 16036 | 1726 |
PRKAA2,MAP3K5,MAP3K6 |
| 4.604e-02 | -3.08 | QSOX1 (quiescin Q6 sulfhydryl oxidase 1) | protein interactions | 5768 | 8 | 3 | 16036 | 1726 |
RP2,LYPD3,GLT8D2 |
| 4.604e-02 | -3.08 | SIX3 (SIX homeobox 3) | protein interactions | 6496 | 8 | 3 | 16036 | 1726 |
TLE1,AES,NR4A3 |
| 4.604e-02 | -3.08 | CAB39L (calcium binding protein 39-like) | protein interactions | 81617 | 8 | 3 | 16036 | 1726 |
CAB39,MX1,ACOT7 |
| 4.604e-02 | -3.08 | Gorasp1 (golgi reassembly stacking protein 1) | protein interactions | 74498 | 8 | 3 | 16036 | 1726 |
LRRFIP2,KIF14,LGALS3BP |
| 4.604e-02 | -3.08 | HIVEP3 (human immunodeficiency virus type I enhancer binding protein 3) | protein interactions | 59269 | 8 | 3 | 16036 | 1726 |
WWP1,FHL1,RUNX2 |
| 4.604e-02 | -3.08 | UFSP2 (UFM1-specific peptidase 2) | protein interactions | 55325 | 8 | 3 | 16036 | 1726 |
HLA-C,CAPN1,FAS |
| 4.604e-02 | -3.08 | MORC2 (MORC family CW-type zinc finger 2) | protein interactions | 22880 | 8 | 3 | 16036 | 1726 |
DHX8,NCOA3,RRBP1 |
| 4.604e-02 | -3.08 | TCEAL2 (transcription elongation factor A (SII)-like 2) | protein interactions | 140597 | 8 | 3 | 16036 | 1726 |
AURKA,CUL4B,TCEAL4 |
| 4.604e-02 | -3.08 | TSEN15 (TSEN15 tRNA splicing endonuclease subunit) | protein interactions | 116461 | 8 | 3 | 16036 | 1726 |
LMO4,TSEN34,NBPF3 |
| 4.604e-02 | -3.08 | TAS2R41 (taste receptor, type 2, member 41) | protein interactions | 259287 | 8 | 3 | 16036 | 1726 |
LASP1,SCRN2,SEPHS1 |
| 4.604e-02 | -3.08 | NPTN (neuroplastin) | protein interactions | 27020 | 8 | 3 | 16036 | 1726 |
FBXO6,LGALS3,SLC25A5 |
| 4.604e-02 | -3.08 | KCNQ2 (potassium channel, voltage gated KQT-like subfamily Q, member 2) | protein interactions | 3785 | 8 | 3 | 16036 | 1726 |
CALM2,CALM3,CALM1 |
| 4.607e-02 | -3.08 | Activation of Kainate Receptors upon glutamate binding | REACTOME pathways | R-HSA-451326 | 32 | 7 | 8202 | 867 |
CALM3,CALM2,GNB5,DLG3,PLCB2,CALM1,DLG1 |
| 4.610e-02 | -3.08 | TNFSF11 (tumor necrosis factor (ligand) superfamily, member 11) | protein interactions | 8600 | 38 | 8 | 16036 | 1726 |
PLK1,FAM213B,AKT1,LMO4,NFKBIA,GALNT7,SBF1,DNAJB9 |
| 4.612e-02 | -3.08 | SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY | MSigDB lists | SUBSTRATE_SPECIFIC_TRANSPORTER_ACTIVITY | 388 | 49 | 17758 | 1761 |
LASP1,SCN5A,SLC2A4,FXYD3,SLC25A13,SLC1A3,SLC7A2,ITPR2,CACNB4,SLC20A1,SLC9A2,SLC9A7,ZFYVE16,KCNN4,SLC16A6,KCNS3,ATP8B1,TRPC1,CACNA1D,SCN2A,SLC12A2,ATP2B1,CLCN3,KCNJ12,SEC61B,PLSCR1,COG2,SLC11A2,ATP1B1,ITPR3,SLC25A5,PCTP,CYB5A,TAPBP,SLC6A6,ATP1A1,KCNMB4,SLC25A4,SLC4A4,KCNK1,ATP7B,SLC9A6,ITPR1,SLC4A3,PITPNA,ATP1B3,SHROOM2,ABCA1,ABCG1 |
| 4.614e-02 | -3.08 | metanephric epithelium development | biological process | GO:0072207 | 20 | 5 | 16441 | 1675 |
HES1,OSR1,SOX8,LGR4,SOX9 |
| 4.614e-02 | -3.08 | N-glycan processing | biological process | GO:0006491 | 20 | 5 | 16441 | 1675 |
MAN2A2,MGAT4A,GNPTAB,MGAT4B,FUT8 |
| 4.614e-02 | -3.08 | mitochondrion morphogenesis | biological process | GO:0070584 | 20 | 5 | 16441 | 1675 |
MTM1,MYH14,BCL2L1,DNM1L,BAX |
| 4.614e-02 | -3.08 | negative regulation of nucleoside metabolic process | biological process | GO:0045978 | 20 | 5 | 16441 | 1675 |
PPIF,RHOA,PPARA,TP53,IER3 |
| 4.614e-02 | -3.08 | establishment of mitotic spindle orientation | biological process | GO:0000132 | 20 | 5 | 16441 | 1675 |
CENPA,GPSM2,NDE1,SPRY2,NDC80 |
| 4.614e-02 | -3.08 | wound healing, spreading of cells | biological process | GO:0044319 | 20 | 5 | 16441 | 1675 |
ARHGAP24,RHOA,CYR61,ACVRL1,DDR1 |
| 4.614e-02 | -3.08 | positive regulation of branching involved in ureteric bud morphogenesis | biological process | GO:0090190 | 20 | 5 | 16441 | 1675 |
SOX8,HOXB7,LGR4,SOX9,SIX4 |
| 4.614e-02 | -3.08 | positive regulation of protein oligomerization | biological process | GO:0032461 | 20 | 5 | 16441 | 1675 |
IDE,BMF,FAS,TP53,BAX |
| 4.614e-02 | -3.08 | negative regulation of toll-like receptor signaling pathway | biological process | GO:0034122 | 20 | 5 | 16441 | 1675 |
DAB2IP,LGR4,PIK3AP1,F2RL1,NOD2 |
| 4.614e-02 | -3.08 | positive regulation of focal adhesion assembly | biological process | GO:0051894 | 20 | 5 | 16441 | 1675 |
EPB41L5,PTPRJ,FMN1,COL16A1,SDC4 |
| 4.614e-02 | -3.08 | negative regulation of ATP metabolic process | biological process | GO:1903579 | 20 | 5 | 16441 | 1675 |
PPIF,RHOA,PPARA,TP53,IER3 |
| 4.614e-02 | -3.08 | endoplasmic reticulum calcium ion homeostasis | biological process | GO:0032469 | 20 | 5 | 16441 | 1675 |
TMBIM6,BCAP31,WFS1,ITPR1,BAX |
| 4.614e-02 | -3.08 | epiboly involved in wound healing | biological process | GO:0090505 | 20 | 5 | 16441 | 1675 |
ARHGAP24,RHOA,CYR61,ACVRL1,DDR1 |
| 4.614e-02 | -3.08 | coenzyme binding | molecular function | GO:0050662 | 182 | 26 | 16491 | 1673 |
ACBD5,SIRT1,PRODH,ALDH6A1,CRYM,GCLC,OGDHL,AIFM2,IDH1,SPR,TP53I3,POR,DUOX1,ACADSB,ALDH1A3,DBI,AOX1,ECI2,DHTKD1,MDH1,AHCY,CRY2,ACOX2,AIFM3,ACOT7,XDH |
| 4.618e-02 | -3.08 | Znf_FYVE-rel | interpro domains | IPR017455 | 34 | 7 | 18293 | 1814 |
ZFYVE16,FGD6,PLEKHF1,PIKFYVE,ZFYVE9,RIMS2,FGD1 |
| 4.618e-02 | -3.08 | PAS | interpro domains | IPR000014 | 34 | 7 | 18293 | 1814 |
AHRR,NCOA3,PER3,EPAS1,AHR,NCOA2,PASK |
| 4.618e-02 | -3.08 | PID_HDAC_CLASSII_PATHWAY | MSigDB lists | PID_HDAC_CLASSII_PATHWAY | 34 | 7 | 17758 | 1761 |
HDAC6,ADRBK1,NR3C1,GATA2,HDAC11,HDAC9,BCL6 |
| 4.618e-02 | -3.08 | BIOCARTA_BCR_PATHWAY | MSigDB lists | BIOCARTA_BCR_PATHWAY | 34 | 7 | 17758 | 1761 |
CALM2,CALM3,PLCG1,ELK1,FOS,SYK,CALM1 |
| 4.618e-02 | -3.08 | VIRAL_REPRODUCTIVE_PROCESS | MSigDB lists | VIRAL_REPRODUCTIVE_PROCESS | 34 | 7 | 17758 | 1761 |
TOP2A,WWP1,MDFIC,TNIP1,APOBEC3G,ITCH,WWP2 |
| 4.618e-02 | -3.08 | STEARMAN_TUMOR_FIELD_EFFECT_UP | MSigDB lists | STEARMAN_TUMOR_FIELD_EFFECT_UP | 34 | 7 | 17758 | 1761 |
SCARB2,NOV,CTSZ,IQGAP1,SIRPA,SAT1,SOCS3 |
| 4.621e-02 | -3.07 | MTIF2 (mitochondrial translational initiation factor 2) | protein interactions | 4528 | 19 | 5 | 16036 | 1726 |
DIRAS3,NUDT6,TTC39B,HSPB1,ARHGEF26 |
| 4.621e-02 | -3.07 | RHOBTB3 (Rho-related BTB domain containing 3) | protein interactions | 22836 | 19 | 5 | 16036 | 1726 |
RHOBTB2,NRG1,PLIN3,CCNB1,FAS |
| 4.621e-02 | -3.07 | CNOT10 (CCR4-NOT transcription complex subunit 10) | protein interactions | 25904 | 19 | 5 | 16036 | 1726 |
TNRC6C,CNOT6L,EPAS1,CNOT8,PPP6R1 |
| 4.621e-02 | -3.07 | RFX1 (regulatory factor X, 1 (influences HLA class II expression)) | protein interactions | 5989 | 19 | 5 | 16036 | 1726 |
HDAC1,NCOA3,ADD1,NFIB,NFIX |
| 4.621e-02 | -3.07 | TRPC5 (transient receptor potential cation channel, subfamily C, member 5) | protein interactions | 7224 | 19 | 5 | 16036 | 1726 |
STMN3,MX1,TRPC1,ITPR3,ITPR1 |
| 4.629e-02 | -3.07 | ABC transporters | KEGG pathways | hsa02010 | 44 | 9 | 6908 | 758 |
ABCG2,ABCA2,ABCB1,TAP1,ABCD1,ABCA1,ABCG1,ABCD4,ABCC1 |
| 4.629e-02 | -3.07 | ABC transporters | KEGG pathways | ko02010 | 44 | 9 | 6908 | 758 |
ABCB1,ABCG2,ABCA2,TAP1,ABCD1,ABCA1,ABCG1,ABCD4,ABCC1 |
| 4.632e-02 | -3.07 | RasGEF_N | pfam domains | PF00618 | 20 | 5 | 16629 | 1696 |
RASGRF1,RASGEF1A,RAPGEF2,RASGRP1,RASGRP2 |
| 4.632e-02 | -3.07 | IGFBP | pfam domains | PF00219 | 20 | 5 | 16629 | 1696 |
NOV,IGFBP2,IGFBP6,CTGF,CYR61 |
| 4.638e-02 | -3.07 | LEIN_CEREBELLUM_MARKERS | MSigDB lists | LEIN_CEREBELLUM_MARKERS | 79 | 13 | 17758 | 1761 |
EXPH5,ARHGEF37,DNAJC3,CALB2,SYNE2,NEK2,COL18A1,RNF182,ICMT,DHRS3,ETV4,TRIM62,SYTL3 |
| 4.649e-02 | -3.07 | SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone) | protein interactions | 10910 | 73 | 13 | 16036 | 1726 |
LRRC42,NLRP4,PLK1,LLGL2,NR4A1,S100A4,HDAC11,NOD2,PHLPP1,IDH1,AIP,S100A6,SEPHS1 |
| 4.649e-02 | -3.07 | TARS (threonyl-tRNA synthetase) | protein interactions | 6897 | 73 | 13 | 16036 | 1726 |
BCAR3,GFPT1,HLA-B,PRKAG2,UGP2,CORO1C,FAM114A1,AURKA,HSPB1,DVL2,VPS26A,DCP2,ELF3 |
| 4.656e-02 | -3.07 | - | gene3d domains | 3.90.290.10 | 8 | 3 | 9988 | 1080 |
LTBP1,LTBP2,LTBP3 |
| 4.671e-02 | -3.06 | EGF-like_Ca-bd_dom | interpro domains | IPR001881 | 103 | 16 | 18293 | 1814 |
LTBP1,FBLN5,CELSR2,LRP4,DNER,FBLN1,LTBP3,FAT4,NPNT,MEGF8,MATN2,BMP1,EGFL7,NOTCH3,LTBP2,TLL2 |
| 4.673e-02 | -3.06 | negative regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000515 | 14 | 4 | 16441 | 1675 |
C10orf54,JAK3,BCL6,SOCS5 |
| 4.673e-02 | -3.06 | nonribosomal peptide biosynthetic process | biological process | GO:0019184 | 14 | 4 | 16441 | 1675 |
OPLAH,GCLM,MGST2,GCLC |
| 4.673e-02 | -3.06 | bone maturation | biological process | GO:0070977 | 14 | 4 | 16441 | 1675 |
RHOA,FAT4,SEMA4D,ANO6 |
| 4.673e-02 | -3.06 | positive regulation of cholesterol efflux | biological process | GO:0010875 | 14 | 4 | 16441 | 1675 |
SIRT1,ABCA1,NFKBIA,ABCG1 |
| 4.673e-02 | -3.06 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | GO:0006978 | 14 | 4 | 16441 | 1675 |
TFAP4,SP100,FOXM1,TP53 |
| 4.673e-02 | -3.06 | cerebellar granular layer development | biological process | GO:0021681 | 14 | 4 | 16441 | 1675 |
MDK,SERPINE2,KIF14,NFIX |
| 4.673e-02 | -3.06 | response to muramyl dipeptide | biological process | GO:0032495 | 14 | 4 | 16441 | 1675 |
ERBB2IP,RIPK2,NFKBIA,NOD2 |
| 4.673e-02 | -3.06 | regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032645 | 14 | 4 | 16441 | 1675 |
DDX58,IL18,SYK,RASGRP1 |
| 4.673e-02 | -3.06 | regulation of energy homeostasis | biological process | GO:2000505 | 14 | 4 | 16441 | 1675 |
PRKAA2,NR1D2,PASK,NR4A3 |
| 4.673e-02 | -3.06 | regulation of non-canonical Wnt signaling pathway | biological process | GO:2000050 | 14 | 4 | 16441 | 1675 |
NPHP3,ANKRD6,DACT1,NKD1 |
| 4.673e-02 | -3.06 | regulation of monocyte differentiation | biological process | GO:0045655 | 14 | 4 | 16441 | 1675 |
CTNNBIP1,IRF7,INPP5D,CSF1 |
| 4.675e-02 | -3.06 | V$MYCMAX_03 | MSigDB lists | V$MYCMAX_03 | 238 | 32 | 17758 | 1761 |
LAMP1,ALDH6A1,HOXB7,TESK2,PKN1,NUP62CL,CDKN2C,TFAP4,BMP7,PLCG2,BAX,SNX16,MANF,CITED2,CLIP2,SOCS5,SIRT1,PHF20L1,PLEKHA6,SHMT1,LONRF3,CBX6,OGDHL,GNAS,ALDH3B1,TIMM8A,KBTBD2,HOXA9,CTSA,C1orf43,RAB3IL1,RNF146 |
| 4.679e-02 | -3.06 | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN | MSigDB lists | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN | 87 | 14 | 17758 | 1761 |
TOP2A,APLP2,TXN,S100A4,RANBP1,IGFBP2,HMGA1,PKMYT1,ITPKA,UBE2C,PLCB2,BARD1,LBR,TMEM131 |
| 4.679e-02 | -3.06 | HALLMARK_IL6_JAK_STAT3_SIGNALING | MSigDB lists | HALLMARK_IL6_JAK_STAT3_SIGNALING | 87 | 14 | 17758 | 1761 |
IL17RB,PDGFC,IL15RA,ACVRL1,IL6ST,CSF1,CD9,TNFRSF12A,IL13RA1,PIM1,IL18R1,LEPR,FAS,SOCS3 |
| 4.679e-02 | -3.06 | KEGG_ERBB_SIGNALING_PATHWAY | MSigDB lists | KEGG_ERBB_SIGNALING_PATHWAY | 87 | 14 | 17758 | 1761 |
PLCG1,AKT1,SHC3,PLCG2,PIK3R1,PIK3CA,CDKN1B,ERBB2,NRG2,NRG1,ERBB3,PIK3CD,ELK1,GAB1 |
| 4.685e-02 | -3.06 | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | MSigDB lists | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | 56 | 10 | 17758 | 1761 |
HMMR,CDKN2C,CENPA,FOXM1,CDC20,NDC80,MYBL2,AURKA,LBR,CDK1 |
| 4.685e-02 | -3.06 | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | MSigDB lists | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | 56 | 10 | 17758 | 1761 |
EPCAM,MID1IP1,EPAS1,SPINT2,HTATIP2,IL13RA1,ARMCX6,S100A2,ABCA1,LZTS1 |
| 4.687e-02 | -3.06 | beta-Alanine metabolism | KEGG pathways | ko00410 | 31 | 7 | 6908 | 758 |
ALDH7A1,ALDH3B1,ALDH2,ALDH6A1,GAD1,ALDH3A2,ALDH1A3 |
| 4.687e-02 | -3.06 | beta-Alanine metabolism | KEGG pathways | hsa00410 | 31 | 7 | 6908 | 758 |
ALDH7A1,ALDH3B1,ALDH2,ALDH6A1,GAD1,ALDH3A2,ALDH1A3 |
| 4.688e-02 | -3.06 | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | 95 | 15 | 17758 | 1761 |
BIN1,GNAS,POPDC3,CDKN1C,SYNE2,SPINT2,CACNA2D2,NDRG2,ALPK3,ERBB3,NCAM1,COBL,PKIA,IGSF3,RRAGD |
| 4.689e-02 | -3.06 | EphA2_TM | pfam domains | PF14575 | 14 | 4 | 16629 | 1696 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.689e-02 | -3.06 | Cyt-b5 | pfam domains | PF00173 | 14 | 4 | 16629 | 1696 |
NENF,FADS2,CYB5A,PGRMC1 |
| 4.689e-02 | -3.06 | Ephrin_lbd | pfam domains | PF01404 | 14 | 4 | 16629 | 1696 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.693e-02 | -3.06 | positive regulation of Wnt signaling pathway | biological process | GO:0030177 | 165 | 24 | 16441 | 1675 |
LGR4,PSMB4,ASPM,PSME2,AMER1,PSMD10,PSME1,PSMA4,PPP2R3A,PSMD1,RNF220,GPRC5B,FGFR2,ANKRD6,DACT1,NKD1,DIXDC1,LRRK1,WNT3A,FZD5,ZRANB1,DVL2,RNF146,SULF2 |
| 4.694e-02 | -3.06 | multi-multicellular organism process | biological process | GO:0044706 | 215 | 30 | 16441 | 1675 |
THRB,GRN,SERPINE2,AKT1,THRA,HEXB,GRIN1,UBE2A,FOS,ETS1,DDR1,FBLN1,EMP2,TEAD3,GNAS,DAZAP1,CYP1A1,ITGA3,PTEN,CTSV,CST3,FOSB,AKR1B1,CLDN4,IGFBP2,ACSL4,MAFF,APOL2,COL16A1,PCSK5 |
| 4.695e-02 | -3.06 | human chr17q23.3 | chromosome location | human chr17q23.3 | 28 | 5 | 26250 | 1887 |
MAP3K3,TEX2,CYB561,TANC2,DCAF7 |
| 4.703e-02 | -3.06 | regulation of cartilage development | biological process | GO:0061035 | 62 | 11 | 16441 | 1675 |
RUNX2,CTGF,CYR61,ACVRL1,SOX9,BMP1,TGFBR1,LOXL2,FAM101B,RARG,POR |
| 4.703e-02 | -3.06 | oligodendrocyte differentiation | biological process | GO:0048709 | 62 | 11 | 16441 | 1675 |
CDKN2C,WASF3,PTPRJ,PTEN,HDAC11,SOX9,CD9,DUSP10,ERBB2,NRG1,SOX8 |
| 4.703e-02 | -3.06 | regulation of osteoclast differentiation | biological process | GO:0045670 | 62 | 11 | 16441 | 1675 |
GNAS,CA2,INPP5D,UBASH3B,CSF1,PIK3R1,MITF,INPP4B,FAM213A,TMEM64,FOS |
| 4.708e-02 | -3.06 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | 195 | 27 | 17758 | 1761 |
ALDH2,TXN,IL15RA,GNPDA1,TAP1,PDIA5,UBE2A,AK4,IL13RA1,CD40,IER3,LRRC42,FUCA1,RCN1,TNS3,TYMP,SLCO4A1,CORO1C,DAPK1,CSTF2,TUBG1,GOT1,LRRK1,GLA,LGMN,BTBD3,LAMP3 |
| 4.708e-02 | -3.06 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | 195 | 27 | 17758 | 1761 |
MRC2,ST14,TACC1,RPS6KA1,HLA-E,DRAP1,INPP5D,XYLT1,TMX4,MRS2,AES,SEPP1,GSTP1,ERP29,ALDH5A1,UTP14C,TRAF3IP1,MDFIC,MAP3K5,ZMIZ1,ARF6,USF2,ALDH3A2,PPP6R1,CBX7,ATP2B1,TMEM131 |
| 4.708e-02 | -3.06 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 27 | 17758 | 1761 |
CPD,LASP1,MMD,CAMKK1,PRKCQ,NCKAP1,LDB2,BSDC1,SH3KBP1,ATP6V0B,SCNN1A,BANK1,IGF1R,ARSG,GATA2,FAM13B,COL6A1,SPINT2,ATP8B1,EPHB4,PLD1,RASGEF1A,LRP11,EGLN3,LTA4H,F2R,EHD1 |
| 4.708e-02 | -3.06 | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | 195 | 27 | 17758 | 1761 |
DDX58,SLC25A24,PARP12,CEP70,ZCCHC24,GRIN1,EFHD2,HMGN3,DUSP4,EDNRA,NFIX,SOX13,RND3,PLK2,IL6ST,PAPL,SRR,RAB11FIP1,SGK3,DUSP10,NR4A2,OAS3,AHR,ISOC1,CPPED1,JARID2,EHD1 |
| 4.709e-02 | -3.06 | intrinsic component of organelle membrane | cellular component | GO:0031300 | 271 | 36 | 17570 | 1756 |
SUN1,CCDC109B,PINK1,ARMCX3,HLA-E,HLA-F,TAP1,SLC8B1,LBR,BCAP31,HLA-A,SGPL1,B4GALNT1,PQLC2,STIM1,A4GALT,RRBP1,STEAP2,ABCD1,ECE1,HLA-C,TECR,SUN2,SYPL1,AMFR,EMC2,HLA-B,TAPBP,WFS1,DOLPP1,PEX2,SARAF,TRABD2A,MCUR1,ST3GAL1,ESYT2 |
| 4.717e-02 | -3.05 | divalent inorganic cation transport | biological process | GO:0072511 | 266 | 36 | 16441 | 1675 |
CCDC109B,ATP2C2,CACNA2D2,ITPR2,CACNB4,SLC8B1,TMC1,NCS1,CTGF,STIM1,KCNN4,PLCG2,TRPC1,CNNM4,SELK,CACNA1D,TMEM37,SLC39A10,F2R,TPCN1,ATP2B1,ORAI2,SLC39A8,MRS2,ERO1A,ANO6,GRIN1,SLC11A2,ITPR3,CACHD1,ITPR1,SARAF,ITGAV,MCUR1,NIPA1,DENND5B |
| 4.724e-02 | -3.05 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 178 | 25 | 17758 | 1761 |
GCLM,CDK17,CD55,IL15RA,FOXM1,UBE2A,RUNX3,MORF4L2,DUSP4,CASP4,OPTN,ARHGEF10L,TOP2A,PSMD1,GLA,PIM1,TMEM120A,NCAM1,SERPINB1,JAK3,COL16A1,CKAP4,LAMP3,ATG4D,EHD1 |
| 4.729e-02 | -3.05 | ossification | biological process | GO:0001503 | 249 | 34 | 16441 | 1675 |
CTHRC1,MRC2,RUNX2,SORT1,HSPG2,LGR4,THRA,SOX9,CTGF,CYR61,BMP7,IMPAD1,RRBP1,COL6A1,SUCO,TWIST1,OSTF1,WNT3A,MINPP1,RHOA,AKT1,FIGNL1,ANO6,RUNX3,TP53INP2,GPLD1,GNAS,FAT4,TWSG1,SEMA4D,COL13A1,FGFR2,BMP1,SOX8 |
| 4.731e-02 | -3.05 | p75 NTR receptor-mediated signalling | REACTOME pathways | R-HSA-193704 | 82 | 14 | 8202 | 867 |
CASP3,ARHGEF3,RHOA,RIPK2,ARHGEF11,NGFRAP1,NFKBIA,HDAC1,TIAM1,ARHGEF9,ABR,ARHGEF16,ARHGEF4,FGD1 |
| 4.736e-02 | -3.05 | AACATTC,MIR-409-3P | MSigDB lists | AACATTC,MIR-409-3P | 136 | 20 | 17758 | 1761 |
CDK17,KCNIP3,MMD,AMFR,OSGIN2,KCTD12,TGFBR1,GRK6,FZD7,PTPRF,FRAS1,CSNK1G1,FOSB,UBE2J1,TWIST1,NR4A2,HS3ST3B1,MAL2,SLC39A10,CITED2 |
| 4.738e-02 | -3.05 | nicotine degradation III | BIOCYC pathways | HUMAN_PWY66-221 | 7 | 3 | 907 | 115 |
CYP2U1,CYP2S1,AOX1 |
| 4.743e-02 | -3.05 | organic substance transport | biological process | GO:0071702 | 1891 | 214 | 16441 | 1675 |
EXPH5,SLC35D2,ACACB,CRYM,CPT2,SLC25A13,ATP8A1,ARFGEF1,TAP1,SYTL4,HDAC6,CACNB4,NUP62CL,ERP29,ZFYVE16,RAB15,PQLC2,AP1M2,OSBPL3,SLC44A1,SERINC2,ABCA2,SNX16,RAB20,RP2,CTTN,ANO4,TRAM1,MYRIP,S100A13,LAMP2,SLC35C1,EZR,ARFRP1,KIF13A,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,ARF4,OPTN,EDNRA,SLC25A4,UEVLD,GNPTAB,RAB11FIP1,NOD2,ARF6,F2RL1,NXT2,PCSK5,PRKAA2,NFKBIE,GGA1,PEX6,SLC22A31,ABCG2,RAB23,SLC36A4,RAB6A,SLC1A3,FAM21C,LMNA,ATG4A,DOPEY2,CA2,SNX18,RINL,FRAS1,RPL39,KCNN4,SLC16A6,KIF13B,EXOC8,SORL1,CADPS2,SYTL3,NUP85,RIMS2,SNX7,KDELR1,TRAK2,PMPCB,SLC37A1,KIF20A,ANO6,BTN3A2,STRADB,NPC2,ATP8B3,PCTP,SFXN5,STX3,GNAS,SLCO4A1,AP1AR,SCARB2,SLC6A6,PRKAG2,SLC4A4,TIMM8A,MFSD2A,TMEM30A,SLC2A6,NFKBIA,SH3BP4,SLC4A3,ZDHHC7,PITPNA,CTSA,LTBP2,HOOK1,JAK3,TOB1,APOL2,NUP58,SNX30,EHD1,PLA2G4A,MTM1,SLC25A24,SORBS1,SLC2A4,UPF3B,C5orf30,TP53,SLC7A2,MVB12B,BCAP31,ZFYVE9,APPBP2,SYTL2,ATP6V0B,SVBP,ZDHHC12,FABP6,BCL6,ZDHHC23,RPN2,IFIT1,ACSL4,LMAN1,RAB27B,ARL4D,SNX10,F2R,GM2A,CHP1,ATG4D,MYO5B,SEC23A,SEC61B,AKT1,COG2,FZD4,SLC11A2,ATP1B1,RAB38,SNX12,ATP10D,DAG1,TAPBP,DDOST,PEX2,SLC27A1,ABCA1,TTC8,SORT1,CD63,ATP9A,BTN3A1,PDIA3,ANO9,AIP,VPS26A,SLC25A36,ZDHHC21,M6PR,PDIA4,ADORA1,MLPH,SLC27A6,CDK16,RRBP1,ATP8B1,SLC44A2,ABCD1,SYK,SLC16A5,MYO5A,NCOA2,HES1,RAB3B,LCA5,ZC3H11A,PIK3R1,EIF5A2,PPARA,PRICKLE1,YES1,NEURL1B,BBS2,CPTP,RPL12,MAMDC4,RAB11FIP2,SCG2,ARRB1,SPCS3,CEP41,RAB3IL1,ESYT2,ABCG1 |
| 4.744e-02 | -3.05 | NRG1 (neuregulin 1) | protein interactions | 3084 | 66 | 12 | 16036 | 1726 |
HS6ST1,TMEM164,B3GNT2,LIMK1,ATP7B,GYLTL1B,NETO2,ERBB2,C1GALT1C1,ERBB3,DSE,SPTLC2 |
| 4.755e-02 | -3.05 | Hippo signaling pathway | KEGG pathways | ko04390 | 154 | 24 | 6908 | 758 |
NF2,FZD4,FRMD6,TCF7,TGFBR1,SCRIB,MPP5,SAV1,APC2,TEAD3,FZD6,FZD7,CCND1,CTGF,CDH1,LLGL2,BMP7,NKD1,DLG1,FZD5,WNT3A,DLG3,PPP2R2D,DVL2 |
| 4.755e-02 | -3.05 | Hippo signaling pathway | KEGG pathways | hsa04390 | 154 | 24 | 6908 | 758 |
NF2,FZD4,FRMD6,TCF7,TGFBR1,SCRIB,MPP5,SAV1,APC2,TEAD3,FZD6,FZD7,CCND1,CTGF,CDH1,LLGL2,BMP7,NKD1,DLG1,FZD5,WNT3A,DLG3,PPP2R2D,DVL2 |
| 4.759e-02 | -3.05 | Amyotrophic lateral sclerosis (ALS) | KEGG pathways | ko05014 | 51 | 10 | 6908 | 758 |
CASP3,CASP9,TP53,GRIN1,BAX,MAPK11,GRIN2D,BCL2L1,MAP3K5,MAPK12 |
| 4.759e-02 | -3.05 | Amyotrophic lateral sclerosis (ALS) | KEGG pathways | hsa05014 | 51 | 10 | 6908 | 758 |
CASP3,CASP9,TP53,GRIN1,BAX,MAPK11,GRIN2D,BCL2L1,MAP3K5,MAPK12 |
| 4.761e-02 | -3.04 | epithelial cell differentiation | biological process | GO:0030855 | 511 | 64 | 16441 | 1675 |
EXPH5,CASP3,EMX1,GRHL2,NF2,ST14,THRA,IQGAP1,COL18A1,F11R,SDC1,PDGFB,TMC1,PLS3,CYP1A1,MITF,ELF5,CDH3,PDE4D,THRB,AKT1,EZR,TFAP2C,SAV1,CDK1,FZD7,ARHGEF26,BFSP1,SHROOM3,PTK7,PTER,HDAC1,KLF5,NRG1,LTA4H,F2RL1,E2F8,LGALS3,FRMD6,SOX9,GPSM2,ELF3,E2F7,BMP7,CST3,TAGLN2,MYO5A,EPB41L5,HES1,RAPGEF2,SCRIB,FNDC3A,NFIB,PITX2,ONECUT1,ACVRL1,FGFR2,RAP2C,SPINT2,CTSV,HOXB13,SOX8,PLOD3,RARG |
| 4.763e-02 | -3.04 | VIM (vimentin) | protein interactions | 7431 | 228 | 33 | 16036 | 1726 |
PLA2G4A,CASP3,MRPL44,TXN,PINK1,LGALS3,HABP4,ASB9,TP53,PDIA3,PSME1,FBXO6,PKN1,PRKACA,TRIM68,RAD23A,SLC27A6,LRIF1,NUP85,AKT1,CASP9,HMG20B,CDK1,MAN2A2,BFSP1,DNM1L,RYK,TRIOBP,NOD2,ARRB1,HDAC1,HSPB1,CAPN1 |
| 4.765e-02 | -3.04 | HES1 (hes family bHLH transcription factor 1) | protein interactions | 3280 | 45 | 9 | 16036 | 1726 |
SIRT1,HES1,RUNX2,NR4A1,TLE1,HDAC1,FHL1,HDAC6,FANCE |
| 4.765e-02 | -3.04 | PPM1A (protein phosphatase, Mg2+/Mn2+ dependent, 1A) | protein interactions | 5494 | 45 | 9 | 16036 | 1726 |
AKT1,FGFR2,NR4A1,PIK3R1,ARRB1,PRSS22,PKN1,HSPB1,DVL2 |
| 4.765e-02 | -3.04 | GTF3C4 (general transcription factor IIIC subunit 4) | protein interactions | 9329 | 45 | 9 | 16036 | 1726 |
PLCG1,PAPSS2,HEXB,TP53,EZR,BARD1,PPP6R1,EHD1,RAD23A |
| 4.767e-02 | -3.04 | GNAI2 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2) | protein interactions | 2771 | 118 | 19 | 16036 | 1726 |
GCLM,CCDC109B,PLSCR1,NLRX1,PTPRU,ITCH,RGS20,GPSM2,EDNRA,NUCB1,ADORA1,IGF1R,CORO1C,RGS3,ADIPOR1,RGS14,F2R,CCDC88A,MDFI |
| 4.769e-02 | -3.04 | Vinorelbine Action Pathway | SMPDB pathways | SMP00439 | 11 | 4 | 978 | 131 |
RALBP1,ABCB1,ABCC1,TP53 |
| 4.769e-02 | -3.04 | Vinblastine Action Pathway | SMPDB pathways | SMP00436 | 11 | 4 | 978 | 131 |
RALBP1,ABCC1,ABCB1,TP53 |
| 4.774e-02 | -3.04 | PI3K_C2 | smart domains | SM00142 | 8 | 3 | 9131 | 997 |
PIK3C2B,PIK3CD,PIK3CA |
| 4.774e-02 | -3.04 | ORANGE | smart domains | SM00511 | 8 | 3 | 9131 | 997 |
HES1,HES2,BHLHE41 |
| 4.775e-02 | -3.04 | regulation of protein targeting | biological process | GO:1903533 | 292 | 39 | 16441 | 1675 |
DDX58,TCAF1,TXN,PINK1,NFKBIE,THRA,RAB23,ERBB2,PSMD10,TGFBR1,IL18,APC2,IL18R1,NOV,CDH1,DACT1,BMP7,CABP1,FAM20B,DAB2IP,MDFIC,WNT3A,MDFI,CHP1,SIRT1,HES1,RHOA,PIK3R1,LITAF,NBPF3,PRKCQ,FZD7,CDK5R1,NUCB1,NFKBIA,NRG1,FZD5,PKIA,TMEM173 |
| 4.778e-02 | -3.04 | Signaling events mediated by focal adhesion kinase | Pathway Interaction DB | fak_pathway | 54 | 13 | 2227 | 331 |
CCND1,PLCG1,RHOA,ARHGEF28,ARHGEF11,PIK3R1,PIK3CA,ITGAV,YES1,BCAR1,ETS1,RASA1,ARHGAP35 |
| 4.794e-02 | -3.04 | calcium-dependent phospholipid binding | molecular function | GO:0005544 | 55 | 10 | 16491 | 1673 |
PLA2G4A,ANXA3,MCTP1,SYT7,ANXA9,SYT13,SYTL4,SYTL3,SYTL2,ESYT2 |
| 4.794e-02 | -3.04 | regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050730 | 207 | 29 | 16441 | 1675 |
HES1,PDGFC,NF2,RIPK2,IL15,TP53,IL18,TEC,YES1,CD40,PDGFB,PDGFA,APLP2,GPRC5B,ADORA1,SEMA4D,IL6ST,PLPP3,IL31RA,RAP2C,NOD2,EFNA5,NRG1,LRRK1,ERBB3,WNT3A,SYK,DVL2,SOCS5 |
| 4.806e-02 | -3.04 | TRAF5 (TNF receptor-associated factor 5) | protein interactions | 7188 | 59 | 11 | 16036 | 1726 |
DGKH,TRIM8,RIPK2,NGFRAP1,NMI,TNFRSF12A,MAP3K5,CD40,TRAF5,TNFRSF19,RAD23A |
| 4.813e-02 | -3.03 | Signaling mediated by p38-gamma and p38-delta | Pathway Interaction DB | p38gammadeltapathway | 10 | 4 | 2227 | 331 |
SNTA1,CCND1,PKN1,MAPK12 |
| 4.813e-02 | -3.03 | dephosphorylation | biological process | GO:0016311 | 275 | 37 | 16441 | 1675 |
MTM1,SSH1,DLGAP5,PPM1J,INPP5D,TMEM55B,UBASH3B,CTDSPL,PLPPR4,PHLPP1,SBF1,LPIN3,PPP2R3A,PTEN,ALPP,IMPAD1,PALD1,PAPL,PPP4R1,DLG1,DUSP10,MINPP1,PTPRE,CTDSP2,SSH3,PTPRU,PTPN9,DUSP4,PTPRF,NUDT16,ATP1A1,PTPRJ,PLPP3,PHLPP2,INPP4B,PPM1H,CPPED1 |
| 4.820e-02 | -3.03 | trans-Golgi network | cellular component | GO:0005802 | 177 | 25 | 17570 | 1756 |
CPD,PIFO,SCOC,ATP9A,ARFGEF1,RGS20,FURIN,TGOLN2,ARFRP1,SLC11A2,KIF13A,RAB6A,RAB38,SLC9A7,OPTN,GNAS,NUCB1,AP1M2,CDH1,WIPI1,ATP7B,SORL1,GPER1,GCNT1,ARFGEF3 |
| 4.825e-02 | -3.03 | NCOR1 (nuclear receptor corepressor 1) | protein interactions | 9611 | 149 | 23 | 16036 | 1726 |
THRB,SIRT1,SMARCA2,NR3C1,THRA,CD82,CORO2A,PPARA,TP53,MYBL2,ERBB2,KIF11,ETS1,HMGXB4,HDAC9,NCOA3,ETS2,NR1D2,NFKBIA,BCL6,KLF5,RARG,ZBTB33 |
| 4.833e-02 | -3.03 | V$SP1_01 | MSigDB lists | V$SP1_01 | 230 | 31 | 17758 | 1761 |
CYP26B1,GGA1,CAMKK1,GYLTL1B,NFE2L1,KIF1C,MPP5,PDIK1L,MAP3K6,SIX4,SP4,PPP2R3A,COL12A1,MECOM,PIAS3,ARHGEF19,COL13A1,ZFP36,BHLHE41,NFKBIA,CDCA7L,SLC44A1,SRR,BCL6,SERINC2,ECE1,HMGA1,CITED2,GAD1,NCOA2,FRS3 |
| 4.833e-02 | -3.03 | V$HFH1_01 | MSigDB lists | V$HFH1_01 | 230 | 31 | 17758 | 1761 |
CYP26B1,TRIM8,NR4A1,SLC39A8,SERTAD4,ETV5,RGAG1,ARFGEF1,KCTD12,NFIB,PPP2R3A,NIN,NEO1,PITX2,FOXP2,KLF12,TIMM8A,DPYSL2,SLC16A6,LMO4,BDH1,NR4A2,EIF4EBP2,TACSTD2,EFNA5,CACNA1D,PIM1,CITED2,NCAM1,CLIP2,TOB1 |
| 4.850e-02 | -3.03 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | 187 | 26 | 17758 | 1761 |
CHCHD7,PPM1J,TMX4,NDRG2,IL13RA1,ERBB2IP,MGST2,PDK3,ICMT,SLC25A5,ADRBK2,MARCH8,FAM111A,ABHD12,METTL7A,PRCP,PCYOX1,SGK1,C10orf54,LTA4H,NRGN,NDUFA12,SGCB,CRTAP,KLF7,CD33 |
| 4.850e-02 | -3.03 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | 187 | 26 | 17758 | 1761 |
MBP,CPEB4,NR3C1,CAMKK1,TGFBR1,CNTNAP2,RAD17,ITPR2,NCKAP1,TRIB2,PHLDA1,CARD10,SH3KBP1,CYB5A,EDNRA,ARHGEF10L,EPCAM,PTPRF,PPP2R5A,ETS2,POPDC3,AXL,TPST1,EPB41L4A,RGS14,TMEM131 |
| 4.850e-02 | -3.03 | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | 187 | 26 | 17758 | 1761 |
MYL9,PLA2G4A,SPRED1,PDGFC,SORT1,ASAH1,IL18,PRKAR2B,IL13RA1,TMEM170B,DOCK5,ADRBK2,TTYH3,BMP2K,CRISPLD2,NUDT16,SWAP70,CA2,SLC2A6,MTMR11,LTA4H,NRGN,CYBRD1,CPPED1,CCDC88A,CYP1B1 |
| 4.850e-02 | -3.03 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | 187 | 26 | 17758 | 1761 |
NFE2L3,SHMT1,CD82,SLC39A8,C1GALT1C1,IGSF8,NENF,XRCC6BP1,SLC25A43,PHLDA1,MAP3K6,ADRBK2,SNX12,BCAP31,PRIM1,CD109,CPNE2,AGPAT2,BDH1,DBI,FAM83D,MRPS28,TMEM120A,SGCB,C12orf75,RUSC1 |
| 4.850e-02 | -3.03 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | 187 | 26 | 17758 | 1761 |
ORAI2,MRPL44,PPFIBP2,CBX6,BTN3A2,CR2,SLC35C1,EIF2AK1,RNPEP,TNFSF9,AIP,CYP39A1,RBM47,KLF12,ELMO2,CTSC,LMO4,FUT8,DRAM1,STK39,LGMN,ZMIZ1,HOOK1,SYK,FAH,ABCC1 |
| 4.850e-02 | -3.03 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | 187 | 26 | 17758 | 1761 |
GCLM,KIF20A,HJURP,GUSB,DAP,KCTD12,MRAS,RAB38,RAB6A,DHRS3,STK17B,SNX12,GLCE,ATP6V0B,PTPRJ,RNF128,XYLT2,SLC44A1,OPN3,UBE2J1,KLF9,IQGAP3,TRAM1,SERPINB1,ZBTB33,S100A6 |
| 4.854e-02 | -3.03 | midbrain | COSMIC cancer mutations | midbrain | 49 | 9 | 17775 | 1757 |
GNAS,AKT1,FGFR2,RET,PIK3CA,TP53,IDH1,GNA11,PARM1 |
| 4.857e-02 | -3.02 | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | 170 | 24 | 17758 | 1761 |
COL9A3,TBC1D8B,STAU2,CD82,PDCL,COL18A1,CR2,TAPBP,BANK1,ADD3,RALGPS2,GNB5,ACVRL1,FGFR2,CSF1,BDH1,PRKG1,HDAC1,ANXA9,FHL1,GDF11,DLG3,HIPK3,RUSC1 |
| 4.857e-02 | -3.02 | Insulin signaling pathway | KEGG pathways | hsa04910 | 139 | 22 | 6908 | 758 |
PRKAA2,ACACB,SORBS1,SLC2A4,AKT1,TRIP10,PIK3R1,CALM1,CALM3,PRKAR2B,ELK1,PRKACA,RHEB,SOCS3,CALM2,PTPRF,IRS2,PRKAG2,SHC3,PIK3CA,PIK3CD,PHKA2 |
| 4.857e-02 | -3.02 | Insulin signaling pathway | KEGG pathways | ko04910 | 139 | 22 | 6908 | 758 |
PRKAA2,ACACB,SORBS1,SLC2A4,AKT1,TRIP10,PIK3R1,CALM1,CALM3,PRKAR2B,ELK1,PRKACA,RHEB,SOCS3,CALM2,PTPRF,IRS2,PRKAG2,SHC3,PIK3CA,PIK3CD,PHKA2 |
| 4.863e-02 | -3.02 | axis specification | biological process | GO:0009798 | 93 | 15 | 16441 | 1675 |
TTC8,CXXC4,EPB41L5,PITX2,SETDB2,ETS2,TBX18,AURKA,NCKAP1,FZD5,CITED2,STIL,MNS1,COBL,MDFI |
| 4.863e-02 | -3.02 | FRI | smart domains | SM00063 | 19 | 5 | 9131 | 997 |
COL18A1,FZD5,FZD4,FZD7,FZD6 |
| 4.863e-02 | -3.02 | Int_alpha | smart domains | SM00191 | 19 | 5 | 9131 | 997 |
ITGAV,ITGA3,ITGA7,ITGA6,GPLD1 |
| 4.874e-02 | -3.02 | FATTY_ACID_METABOLIC_PROCESS | MSigDB lists | FATTY_ACID_METABOLIC_PROCESS | 64 | 11 | 17758 | 1761 |
FADS2,ALDH5A1,SLC27A6,ACADSB,FAAH,PPARA,ECI2,ADIPOR1,LTA4H,PTGES,CYP4F3 |
| 4.874e-02 | -3.02 | WILCOX_RESPONSE_TO_PROGESTERONE_DN | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_DN | 64 | 11 | 17758 | 1761 |
MYL9,CCND1,FRMD4A,IGF1R,COL6A1,IGFBP2,PIEZO1,LOXL2,L1CAM,COL16A1,METAP2 |
| 4.874e-02 | -3.02 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | MSigDB lists | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | 64 | 11 | 17758 | 1761 |
PLK1,PSMD1,PSMB4,PSME2,CDC20,PTTG1,AURKA,PSMD10,PSME1,UBE2C,PSMA4 |
| 4.876e-02 | -3.02 | Erlotinib Action Pathway | SMPDB pathways | SMP00472 | 3 | 2 | 978 | 131 |
ABCB1,ABCG2 |
| 4.897e-02 | -3.02 | EP450IV | prints domains | PR00465 | 9 | 3 | 4759 | 462 |
CYP26B1,CYP39A1,CYP26A1 |
| 4.897e-02 | -3.02 | NAHEXCHNGR | prints domains | PR01084 | 9 | 3 | 4759 | 462 |
SLC9A6,SLC9A7,SLC9A2 |
| 4.898e-02 | -3.02 | negative regulation of neuron differentiation | biological process | GO:0045665 | 174 | 25 | 16441 | 1675 |
SEMA6B,HES1,RHOA,ASPM,CIT,RAPGEF2,LRP4,EPHA4,SOX9,CDK5R1,DPYSL3,PTEN,SEMA4D,BMP7,PLK2,KIAA0319,DIXDC1,NOTCH3,SEMA3G,GDF11,WNT3A,ARF6,SOX8,SEMA3A,SEMA3B |
| 4.905e-02 | -3.01 | generation of precursor metabolites and energy | biological process | GO:0006091 | 397 | 51 | 16441 | 1675 |
PRKAA2,ACACB,GAA,PINK1,PPP1R2,ENO2,UGP2,GNPDA1,SLC25A13,IQGAP1,CACNA2D2,SLC25A27,CALM3,NDUFA4,CYB561,ITPR2,SLC1A3,COX6C,PRKACA,CALM2,IL6ST,ATP5H,KCNS3,BAX,CACNA1D,PHKA2,NDUFA12,GFPT1,PGM1,PMPCB,AKT1,CALM1,ACO1,OGDHL,PRKAR2B,ITPR3,SLC25A5,IDH1,LEPR,COX20,FECH,GNAS,ENPP1,PRKAG2,ALDH5A1,SLC25A4,ITPR1,NR4A3,PGM2L1,DHTKD1,MDH1 |
| 4.908e-02 | -3.01 | YAGI_AML_SURVIVAL | MSigDB lists | YAGI_AML_SURVIVAL | 120 | 18 | 17758 | 1761 |
PEX6,CORO2A,STAU2,NPC2,LEPR,LBR,APPBP2,SLC9A7,APOBEC3B,ENPP1,TYMP,ATP6V0B,APLP2,SLC25A4,NFKBIA,GTF2F2,VAT1,CLIP2 |
| 4.908e-02 | -3.01 | RB_DN.V1_DN | MSigDB lists | RB_DN.V1_DN | 120 | 18 | 17758 | 1761 |
SEC23A,PSME2,USP18,FURIN,COL18A1,PSME1,PDGFB,KIAA1161,TMCC3,CTSC,CD9,FAM102A,FHL1,LMAN1,SERPINB1,F2RL1,LIFR,STARD3NL |
| 4.909e-02 | -3.01 | V$CHX10_01 | MSigDB lists | V$CHX10_01 | 213 | 29 | 17758 | 1761 |
PLEKHA6,HOXB7,THRA,SYNE2,LDB2,PRKACA,FGF19,NFIB,LTBP3,FZD7,GRM5,NEO1,PITX2,CDKN2C,FOXP2,ADD3,CA2,GRHL1,ELMO2,FLRT3,BHLHE41,MITF,FOSB,BCL6,BMP1,OVOL1,DIXDC1,WNT3A,BTBD3 |
| 4.910e-02 | -3.01 | WHTH_DNA-bd_dom | interpro domains | IPR011991 | 213 | 29 | 18293 | 1814 |
ELK3,DEPDC1,FOXM1,DEPDC4,FOXJ2,ETV5,CUL4B,ELK1,ETS1,FOXL1,H1FX,FOXD2,ELF3,FOXP2,E2F7,HSF2,ETS2,H1F0,ELF5,GTF2F2,IRF2,IRF7,RFX5,PIKFYVE,ETV7,ETV4,E2F8,DVL2,METAP2 |
| 4.916e-02 | -3.01 | negative regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000134 | 101 | 16 | 16441 | 1675 |
PSMB4,PSME2,CTDSPL,TP53,PSMD10,PSME1,PSMA4,JADE1,CCND1,E2F7,PSMD1,PTEN,DACT1,CDKN1B,FHL1,CTDSP2 |
| 4.925e-02 | -3.01 | renal tubule morphogenesis | biological process | GO:0061333 | 70 | 12 | 16441 | 1675 |
CTNNBIP1,HES1,FAT4,LGR4,FMN1,NPNT,SOX9,DLG1,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 4.925e-02 | -3.01 | cytochrome P450 | WikiPathways | WP43 | 62 | 12 | 4455 | 516 |
CYP26B1,CYP1A1,CYP4F11,CYB5R2,CYP2S1,CYP2U1,POR,CYP4F3,CYP39A1,CYP26A1,CYB5A,CYP1B1 |
| 4.938e-02 | -3.01 | PID_FOXO_PATHWAY | MSigDB lists | PID_FOXO_PATHWAY | 49 | 9 | 17758 | 1761 |
SIRT1,PLK1,AKT1,CSNK1G1,BCL6,CDKN1B,SGK1,CCNB1,ZFAND5 |
| 4.938e-02 | -3.01 | MCCLUNG_DELTA_FOSB_TARGETS_8WK | MSigDB lists | MCCLUNG_DELTA_FOSB_TARGETS_8WK | 49 | 9 | 17758 | 1761 |
CALM2,MID1IP1,IMPAD1,CALM1,GRIN1,NFE2L1,CALM3,CRY2,SLC25A5 |
| 4.938e-02 | -3.01 | PID_ARF6_TRAFFICKING_PATHWAY | MSigDB lists | PID_ARF6_TRAFFICKING_PATHWAY | 49 | 9 | 17758 | 1761 |
BIN1,SLC2A4,ITGA3,CDH1,ITGA7,ITGA6,PLD1,ITGAV,ARF6 |
| 4.938e-02 | -3.01 | BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP | 49 | 9 | 17758 | 1761 |
CCNE2,CENPA,UPF3B,DDOST,DLGAP5,NEK2,TUBG1,RRAGD,ABCG1 |
| 4.938e-02 | -3.01 | HALMOS_CEBPA_TARGETS_UP | MSigDB lists | HALMOS_CEBPA_TARGETS_UP | 49 | 9 | 17758 | 1761 |
PLCG1,UAP1,ETS2,EPHA4,KLF5,SERPINI1,CKAP4,BMP2K,FAS |
| 4.939e-02 | -3.01 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 145 | 21 | 17758 | 1761 |
PRSS23,SSH1,LGALS3,S100A4,DIAPH2,TP53I3,NOV,TIMP3,RPS6KA2,TAF1B,PTEN,COL13A1,ATP5H,CALD1,HOXA9,N4BP3,PRKG1,MTMR11,SGCB,ARHGEF9,ABCC1 |
| 4.942e-02 | -3.01 | JANUSKINASE | prints domains | PR01823 | 4 | 2 | 4759 | 462 |
JAK1,JAK3 |
| 4.942e-02 | -3.01 | P38MAPKINASE | prints domains | PR01773 | 4 | 2 | 4759 | 462 |
MAPK11,MAPK12 |
| 4.942e-02 | -3.01 | PROTEASEAR | prints domains | PR01428 | 4 | 2 | 4759 | 462 |
F2R,F2RL1 |
| 4.942e-02 | -3.01 | ADPTRNSLCASE | prints domains | PR00927 | 4 | 2 | 4759 | 462 |
SLC25A4,SLC25A5 |
| 4.942e-02 | -3.01 | THYROIDHORMR | prints domains | PR00546 | 4 | 2 | 4759 | 462 |
THRB,THRA |
| 4.951e-02 | -3.01 | pulmonary_blastoma | COSMIC cancer mutations | pulmonary_blastoma | 666 | 79 | 17775 | 1757 |
ILDR1,NCKAP5,SLC2A4,CUL4B,ARFGEF1,TP53,FTH1,KREMEN1,TMPRSS4,SLC9A7,CPNE2,SIPA1L2,MUC16,RNF220,AP1M2,CYP4F11,MKRN3,ANKRD12,CTTN,ANO4,TLN2,TSPAN1,TRAM1,ZNF462,CLCN3,PTPRU,HSPA12A,C15orf39,SP4,ANKRD10,JAK1,SHROOM3,UEVLD,MAP2,SIPA1L1,TRAF3IP1,TLE1,TANC2,FGD1,TNRC6C,ARAP3,GGA1,CNTNAP2,B4GALT4,SBF1,BEX2,PARM1,NRP2,DIRAS3,TOP2A,BHLHE41,KIF13B,ABCD1,MAPK11,CADPS2,CACNA1D,PIKFYVE,MYLIP,ATP2B1,RIMS2,NCOA2,CHSY3,ACBD5,OXR1,SYBU,ZKSCAN2,DCP2,FAT4,SERPINA1,SYT7,FAAH,ZNF214,SLC4A3,CSTF2,ALPK3,CABIN1,GRAMD1C,PTGES,ABCG1 |
| 4.951e-02 | -3.01 | pleura-pulmonary_blastoma | COSMIC cancer mutations | pleura-pulmonary_blastoma | 666 | 79 | 17775 | 1757 |
ILDR1,NCKAP5,SLC2A4,CUL4B,ARFGEF1,TP53,FTH1,KREMEN1,TMPRSS4,SLC9A7,CPNE2,SIPA1L2,MUC16,RNF220,AP1M2,CYP4F11,MKRN3,ANKRD12,CTTN,ANO4,TLN2,TSPAN1,TRAM1,ZNF462,CLCN3,PTPRU,HSPA12A,C15orf39,SP4,ANKRD10,JAK1,SHROOM3,UEVLD,MAP2,SIPA1L1,TRAF3IP1,TLE1,TANC2,FGD1,TNRC6C,ARAP3,GGA1,CNTNAP2,B4GALT4,SBF1,BEX2,PARM1,NRP2,DIRAS3,TOP2A,BHLHE41,KIF13B,ABCD1,MAPK11,CADPS2,CACNA1D,PIKFYVE,MYLIP,ATP2B1,RIMS2,NCOA2,CHSY3,ACBD5,OXR1,SYBU,ZKSCAN2,DCP2,FAT4,SERPINA1,SYT7,FAAH,ZNF214,SLC4A3,CSTF2,ALPK3,CABIN1,GRAMD1C,PTGES,ABCG1 |
| 4.953e-02 | -3.01 | pigment granule | cellular component | GO:0048770 | 103 | 16 | 17570 | 1756 |
LAMP1,SYPL1,CD63,PDIA3,GGH,RAB38,ERP29,SYTL2,PDIA4,ATP1A1,AHCY,ATP1B3,RAB27B,PDIA6,MYRIP,MYO5A |
| 4.953e-02 | -3.01 | melanosome | cellular component | GO:0042470 | 103 | 16 | 17570 | 1756 |
LAMP1,SYPL1,CD63,PDIA3,GGH,RAB38,ERP29,SYTL2,PDIA4,ATP1A1,AHCY,ATP1B3,RAB27B,PDIA6,MYRIP,MYO5A |
| 4.959e-02 | -3.00 | LIM | pfam domains | PF00412 | 70 | 12 | 16629 | 1696 |
LMO7,FBLIM1,LASP1,PDLIM3,LMO4,LIMK1,PRICKLE3,LHX6,LMCD1,PRICKLE1,LIMCH1,FHL1 |
| 4.968e-02 | -3.00 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | 390 | 49 | 17758 | 1761 |
EXPH5,MRC2,PINK1,NQO1,CDKN1C,NUAK1,CRYM,FXYD3,CALB2,ATP2C2,PKP2,PLXNA1,SNN,DDR1,PDGFB,PHLDA1,HPCAL4,NRP2,ARHGEF16,LMNA,TMEM63A,SNTA1,SCNN1A,MLPH,MITF,RRBP1,PIK3CD,EPHB4,ARL4D,MAST4,ETV7,FADS2,MBP,PCDH1,NR4A1,PLAUR,FURIN,FBXO9,ARFRP1,GNA11,PRX,ALDH3B1,PVRL2,TRIOBP,RAB11FIP1,ARRB1,NRG1,LTBP2,PTGES |
| 4.970e-02 | -3.00 | V$E12_Q6 | MSigDB lists | V$E12_Q6 | 248 | 33 | 17758 | 1761 |
FBLIM1,SORT1,HOXB7,KLHL13,ITGA6,SELL,CAMK1D,PKN1,SPTB,CYP26A1,EPDR1,RNF220,GATA2,MEGF8,FUT8,ARVCF,MYH14,NR4A1,CORO2A,PPARA,C1GALT1C1,IGSF8,ARHGAP24,GNAS,PTPRJ,PRKAG2,SMTNL2,COQ10A,SCG2,HMGA1,OSR1,DEF6,EGLN1 |
| 4.977e-02 | -3.00 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1697 | 193 | 16441 | 1675 |
LGR4,EPAS1,CNOT8,HEXB,RET,MORF4L2,CAMK1D,CCNB1,PDGFB,CALM2,EPCAM,HSF2,GRHL1,NPNT,ZFP36,IL31RA,MITF,FOSB,ELF5,IRF2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,NFE2L1,TFAP2C,LDB2,SAV1,ARF4,EDNRA,KDM4D,AHRR,MDK,KLF12,NOD2,HDAC1,TRAF5,F2RL1,E2F8,MAFF,HOXC13,NR2C2,DDX58,PRKAA2,RUNX2,CDKN1C,ITGA6,SOX9,ETV5,CALM3,PSIP1,LMNA,MECOM,ELF3,TFAP4,DAZAP1,IGF1R,CYR61,GATA2,NEK2,MDFIC,MYDGF,WNT3A,NUP85,GPR161,ELK3,RGMB,SALL4,STAT4,CALM1,MYBL2,ELK1,TP53INP2,NFIB,GNAS,NUDT16,ONECUT1,NCOA3,ETS2,PLPP3,SETD3,NFKBIA,NLRC5,NR4A2,TOB1,RARG,TMEM173,KLF7,GRHL2,ARMCX3,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,LPIN3,PDGFA,SS18,CDH1,SP100,LMO4,DAB2IP,TWIST1,NOTCH3,ETV4,F2R,MED30,DVL2,CTH,SIRT1,TIMP2,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,FZD7,NFIX,JADE1,RBL1,WFS1,NRG1,IRF7,KLF5,ABCA1,GLIS3,ANXA3,PINK1,NKX3-1,TNRC6C,CKAP2,ARHGEF11,PBX3,TGFBR1,HMGN3,ETS1,PARM1,TEAD3,SIX4,WWP2,IRF2BPL,TOP2A,E2F7,PTEN,BMP7,CST3,TOX2,GTF2F2,TFAP2A,BAX,TRIM21,CITED2,TRIM62,NCOA2,NFE2L3,PDGFC,HES1,PLSCR1,NR3C1,BCL9,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,RUNX3,YES1,FOS,PITX2,FGFR2,NR1D2,ACVRL1,NR4A3,ARRB1,HMGA1,GPER1,OSR1,FZD5,ZMIZ1,SOX8,USF2,AHR,RGMA |
| 4.978e-02 | -3.00 | ATPASE_ACTIVITY | MSigDB lists | ATPASE_ACTIVITY | 112 | 17 | 17758 | 1761 |
PEX6,RALBP1,ABCG2,DHX8,ATP1B1,PIF1,ABCD4,TOP2A,TAPBP,ATP1A1,ATP7B,ABCA2,ATP8B1,ATP1B3,ATP2B1,ABCC1,ABCG1 |
| 4.978e-02 | -3.00 | I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 112 | 17 | 17758 | 1761 |
MAP3K3,RHOA,RIPK2,LITAF,CD40,SLC20A1,CARD10,PRDX4,CARD8,PLK2,TSPAN6,SECTM1,NOD2,SLC44A2,NDFIP1,TRAF5,F2R |
| 4.978e-02 | -3.00 | phosphatidylinositol phosphate phosphatase activity | molecular function | GO:0052866 | 27 | 6 | 16491 | 1673 |
MTM1,PIKFYVE,PTEN,TMEM55B,INPP5D,INPP4B |
| 4.985e-02 | -3.00 | IGFBP_N_2 | prosite domains | PS51323 | 20 | 5 | 11866 | 1235 |
NOV,IGFBP2,IGFBP6,CTGF,CYR61 |
| 4.989e-02 | -3.00 | APC (adenomatous polyposis coli) | protein interactions | 324 | 134 | 21 | 16036 | 1726 |
DLGAP1,EXPH5,NCKAP5,EPAS1,IQGAP1,SCRIB,ERBB2IP,PRKACA,RANBP9,KIF5B,PSMD1,PPP2R5A,TFAP2A,TRIM21,BUB1,DLG3,ZRANB1,NUP58,NEB,RNF146,ARHGEF4 |
| 4.990e-02 | -3.00 | PENG_GLUCOSE_DEPRIVATION_DN | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_DN | 162 | 23 | 17758 | 1761 |
MICB,GTF2A2,H2AFV,SLC25A5,KIF11,CDK1,ARF4,FANCI,DAPK2,WEE1,ATP6V0B,HLF,PPP2R5A,ARTN,DPYSL2,PAPSS1,RRBP1,BMP1,AURKA,TMBIM6,TRAF5,ESPL1,EHD1 |
| 4.990e-02 | -3.00 | POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 162 | 23 | 17758 | 1761 |
RALBP1,CASP9,TP53,ERBB2,STRADB,PKN1,MAP3K6,CARD10,EDNRA,CCND1,GNAS,CARD8,MADD,MAP3K9,BAX,SERINC2,MDFIC,MAP3K5,PLCB2,AIFM3,F2R,CCDC88A,MDFI |
| 4.990e-02 | -3.00 | oligodendroglioma | COSMIC cancer mutations | oligodendroglioma | 21 | 5 | 17775 | 1757 |
CDKN2C,NF2,IDH1,PTEN,TP53 |
| 4.990e-02 | -3.00 | Merkel_cell_carcinoma | COSMIC cancer mutations | Merkel_cell_carcinoma | 21 | 5 | 17775 | 1757 |
NF2,AKT1,PTEN,PIK3CA,TP53 |
| 4.990e-02 | -3.00 | salivary_gland-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-mucoepidermoid_carcinoma | 21 | 5 | 17775 | 1757 |
ERBB2,CHCHD7,PTEN,PIK3CA,TP53 |
| 4.992e-02 | -3.00 | LEIN_OLIGODENDROCYTE_MARKERS | MSigDB lists | LEIN_OLIGODENDROCYTE_MARKERS | 72 | 12 | 17758 | 1761 |
MBP,UGT8,CA2,SLC44A1,ABCA2,SGK1,TMBIM6,ANLN,SEPP1,SERPINB1,FRMD4B,TMEM63A |
| 4.992e-02 | -3.00 | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | MSigDB lists | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | 72 | 12 | 17758 | 1761 |
MAPKAPK2,RPS6KA2,RIPK2,RPS6KA1,NFKBIA,NOD2,IRF7,MAPK11,DUSP4,ELK1,FOS,CDK1 |
| 4.992e-02 | -3.00 | CTCAAGA,MIR-526B | MSigDB lists | CTCAAGA,MIR-526B | 72 | 12 | 17758 | 1761 |
AKIRIN1,ONECUT1,NF2,ARRB1,TWIST1,TGFBR1,PRKCQ,NPHP3,PDIA6,DNER,CNPY3,CPEB2 |
| 4.992e-02 | -3.00 | Znf_LIM | interpro domains | IPR001781 | 72 | 12 | 18293 | 1814 |
LMO7,FBLIM1,LASP1,PDLIM3,PRICKLE3,LMO4,LIMK1,LHX6,LMCD1,PRICKLE1,LIMCH1,FHL1 |
| 4.993e-02 | -3.00 | Kinesins | REACTOME pathways | R-HSA-983189 | 26 | 6 | 8202 | 867 |
KIF23,KIF5B,CENPE,KIF20A,KIF11,KLC3 |
| 4.994e-02 | -3.00 | SULFATASE_2 | prosite domains | PS00149 | 14 | 4 | 11866 | 1235 |
GNS,ARSB,ARSG,GALNS |
| 4.994e-02 | -3.00 | RECEPTOR_TYR_KIN_V_1 | prosite domains | PS00790 | 14 | 4 | 11866 | 1235 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.994e-02 | -3.00 | RECEPTOR_TYR_KIN_V_2 | prosite domains | PS00791 | 14 | 4 | 11866 | 1235 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.994e-02 | -3.00 | EPH_LBD | prosite domains | PS51550 | 14 | 4 | 11866 | 1235 |
EPHA10,EPHB4,EPHA1,EPHA4 |
| 4.995e-02 | -3.00 | GSE3982_DC_VS_MAC_UP | MSigDB lists | GSE3982_DC_VS_MAC_UP | 179 | 25 | 17758 | 1761 |
NFE2L3,ING1,LRRFIP2,UGP2,ADCK3,DAP,CORO2A,ARL4C,ABCG2,TRIB2,HDAC9,SLC25A36,CCDC92,PDGFA,RAB15,C19orf66,SETD3,RIMS3,SERINC2,OPN3,NR4A3,TACSTD2,RFX5,IGSF3,LAMP3 |
| 4.995e-02 | -3.00 | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | 179 | 25 | 17758 | 1761 |
TXN,TSPAN15,ANO6,EPS8,ERBB2IP,RAB6A,VASH1,MRPS36,ZFAND5,TXNDC11,EFNB1,GNS,DPYSL2,CORO1C,FRAS1,SETD3,PHTF1,LRIG1,MADD,NETO2,ANKRD12,CNNM4,RP2,NCOA2,MELK |
| 4.995e-02 | -3.00 | BENPORATH_MYC_TARGETS_WITH_EBOX | MSigDB lists | BENPORATH_MYC_TARGETS_WITH_EBOX | 222 | 30 | 17758 | 1761 |
PLA2G4A,SIRT1,PLK1,HES1,SLC2A4,ALDH2,TXN,MFI2,CD63,FOXM1,EIF5A2,CCNB1,ELK1,GSTP1,LBR,LMNA,ARF4,MAN2A2,CCND1,WEE1,ETS2,PTEN,DCK,GALNS,DBI,BAX,IRF2,GLA,ARSB,FAH |
| 4.999e-02 | -3.00 | human chr3q25.31 | chromosome location | human chr3q25.31 | 12 | 3 | 26250 | 1887 |
PLCH1,LINC00886,TIPARP |
| 4.999e-02 | -3.00 | human chr8p11.22 | chromosome location | human chr8p11.22 | 12 | 3 | 26250 | 1887 |
TM2D2,TACC1,RAB11FIP1 |